pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6635-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 52 51 7,000 4,081E-10 7,521E-07 GO:0051325|interphase, ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 6,000 9,276E-10 8,547E-07 ! androgen receptor signaling pathway GO:0030521 24 24 4,000 2,285E-07 1,404E-04 ! gland development GO:0048732 51 49 5,000 3,544E-07 1,633E-04 ! G1 phase GO:0051318 13 12 3,000 5,192E-07 1,914E-04 ! regulation of epithelial cell proliferation GO:0050678 29 29 4,000 6,247E-07 1,919E-04 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 3,000 7,467E-07 1,966E-04 ! prostate gland development GO:0030850 5 5 2,000 1,949E-06 4,489E-04 ! negative regulation of protein kinase activity GO:0006469 37 37 4,000 2,214E-06 4,534E-04 ! negative regulation of kinase activity GO:0033673 38 38 4,000 2,538E-06 4,678E-04 ! urogenital system development GO:0001655 38 38 4,000 2,538E-06 4,253E-04 ! steroid hormone receptor signaling pathway GO:0030518 38 38 4,000 2,538E-06 3,899E-04 ! negative regulation of transferase activity GO:0051348 40 40 4,000 3,299E-06 4,677E-04 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 4,000 3,299E-06 4,343E-04 ! regulation of lipid kinase activity GO:0043550 6 6 2,000 3,881E-06 4,769E-04 ! negative regulation of T cell proliferation GO:0042130 6 6 2,000 3,881E-06 4,471E-04 GO:0070667|negative regulation of mast cell proliferation, ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 3,881E-06 4,208E-04 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 3,000 6,039E-06 6,183E-04 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 2,000 6,764E-06 6,561E-04 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! negative regulation of T cell activation GO:0050868 7 7 2,000 6,764E-06 6,233E-04 ! gliogenesis GO:0042063 24 24 3,000 1,058E-05 9,288E-04 ! heart development GO:0007507 90 87 5,000 1,083E-05 9,077E-04 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 1,255E-05 1,005E-03 ! negative regulation of cell cycle GO:0045786 92 91 5,000 1,405E-05 1,079E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 1,726E-05 1,272E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 2,005E-05 1,421E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 3,041E-05 2,076E-03 ! G1 phase of mitotic cell cycle GO:0000080 12 11 2,000 3,136E-05 2,064E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 3,136E-05 1,993E-03 GO:0032388|positive regulation of intracellular transport, ! spinal cord development GO:0021510 11 11 2,000 3,136E-05 1,927E-03 ! negative regulation of lymphocyte activation GO:0051250 11 11 2,000 3,136E-05 1,864E-03 ! muscle tissue development GO:0060537 72 70 4,000 5,322E-05 3,065E-03 ! negative regulation of phosphorylation GO:0042326 13 13 2,000 5,391E-05 3,011E-03 ! negative regulation of leukocyte activation GO:0002695 13 13 2,000 5,391E-05 2,922E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 2,000 5,391E-05 2,839E-03 GO:0001952|regulation of cell-matrix adhesion, ! camera-type eye morphogenesis GO:0048593 13 13 2,000 5,391E-05 2,76E-03 ! lung development GO:0030324 38 37 3,000 6,22E-05 3,098E-03 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 2,000 6,833E-05 3,314E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 6,833E-05 3,229E-03 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 2,000 6,833E-05 3,148E-03 GO:0045936|negative regulation of phosphate metabolic process, ! collagen fibril organization GO:0030199 14 14 2,000 6,833E-05 3,072E-03 ! respiratory tube development GO:0030323 40 39 3,000 7,68E-05 3,37E-03 ! respiratory system development GO:0060541 40 39 3,000 7,68E-05 3,292E-03 ! negative regulation of cell activation GO:0050866 15 15 2,000 8,506E-05 3,563E-03 ! cell cycle checkpoint GO:0000075 42 41 3,000 9,375E-05 3,839E-03 ! learning GO:0007612 16 16 2,000 1,043E-04 4,177E-03 ! positive regulation of cell adhesion GO:0045785 17 17 2,000 1,261E-04 4,944E-03 ! myelination GO:0042552 17 17 2,000 1,261E-04 4,841E-03 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 1,356E-04 5,099E-03 ! meiosis I GO:0007127 18 18 2,000 1,507E-04 5,553E-03 ! telencephalon development GO:0021537 19 18 2,000 1,507E-04 5,444E-03 ! ensheathment of neurons GO:0007272 18 18 2,000 1,507E-04 5,34E-03 GO:0008366|axon ensheathment, ! glial cell differentiation GO:0010001 19 19 2,000 1,782E-04 6,196E-03 ! metanephros development GO:0001656 19 19 2,000 1,782E-04 6,081E-03 ! peripheral nervous system development GO:0007422 19 19 2,000 1,782E-04 5,97E-03 ! eye morphogenesis GO:0048592 19 19 2,000 1,782E-04 5,864E-03 ! ossification GO:0001503 50 49 3,000 1,895E-04 6,127E-03 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 3,000 1,895E-04 6,021E-03 ! response to light stimulus GO:0009416 53 52 3,000 2,39E-04 7,467E-03 ! regulation of cell growth GO:0001558 97 96 4,000 2,399E-04 7,369E-03 ! mammary gland development GO:0030879 23 21 2,000 2,425E-04 7,328E-03 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 2,425E-04 7,209E-03 ! regulation of action potential in neuron GO:0019228 21 21 2,000 2,425E-04 7,095E-03 ! regulation of protein transport GO:0051223 53 53 3,000 2,574E-04 7,413E-03 GO:0070201|regulation of establishment of protein localization, ! odontogenesis GO:0042476 22 22 2,000 2,797E-04 7,93E-03 ! spindle organization GO:0007051 22 22 2,000 2,797E-04 7,809E-03 ! muscle organ development GO:0007517 102 100 4,000 2,904E-04 7,987E-03 ! microtubule cytoskeleton organization GO:0000226 55 55 3,000 2,973E-04 8,057E-03 ! regulation of cell adhesion GO:0030155 56 55 3,000 2,973E-04 7,94E-03 ! extracellular structure organization GO:0043062 56 56 3,000 3,188E-04 8,392E-03 ! cell projection assembly GO:0030031 25 23 2,000 3,203E-04 8,314E-03 ! regulation of protein localization GO:0032880 58 57 3,000 3,413E-04 8,737E-03 ! neuron fate specification GO:0048665 5 5 1,000 3,426E-04 8,65E-03 ! forebrain regionalization GO:0021871 5 5 1,000 3,426E-04 8,533E-03 ! filopodium assembly GO:0046847 7 5 1,000 3,426E-04 8,419E-03 GO:0030035|microspike assembly, ! adrenal gland development GO:0030325 5 5 1,000 3,426E-04 8,308E-03 ! astrocyte differentiation GO:0048708 5 5 1,000 3,426E-04 8,2E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 3,426E-04 8,095E-03 ! Schwann cell differentiation GO:0014037 5 5 1,000 3,426E-04 7,993E-03 ! regulation of gliogenesis GO:0014013 5 5 1,000 3,426E-04 7,893E-03 GO:0045685|regulation of glial cell differentiation, ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 3,426E-04 7,795E-03 ! spinal cord motor neuron differentiation GO:0021522 5 5 1,000 3,426E-04 7,7E-03 GO:0021517|ventral spinal cord development, ! cellular response to nutrient GO:0031670 5 5 1,000 3,426E-04 7,608E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 3,426E-04 7,517E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 3,426E-04 7,429E-03 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 3,426E-04 7,342E-03 GO:0007439|ectodermal gut development, ! embryonic gut development GO:0048566 5 5 1,000 3,426E-04 7,258E-03 ! nucleus localization GO:0051647 5 5 1,000 3,426E-04 7,175E-03 ! regulation of action potential GO:0001508 24 24 2,000 3,645E-04 7,549E-03 ! glucan metabolic process GO:0044042 25 24 2,000 3,645E-04 7,465E-03 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of T cell proliferation GO:0042129 25 25 2,000 4,125E-04 8,355E-03 ! negative regulation of immune system process GO:0002683 25 25 2,000 4,125E-04 8,264E-03 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 2,000 4,644E-04 9,203E-03 ! negative regulation of cellular component organization GO:0051129 65 63 3,000 5,016E-04 9,835E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 5,12E-04 9,932E-03 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of B cell proliferation GO:0030888 6 6 1,000 5,12E-04 9,829E-03 ! regulation of activated T cell proliferation GO:0046006 6 6 1,000 5,12E-04 9,727E-03 ! artery development GO:0060840 6 6 1,000 5,12E-04 9,628E-03 GO:0048844|artery morphogenesis, ! oligodendrocyte differentiation GO:0048709 6 6 1,000 5,12E-04 9,531E-03 ! ER overload response GO:0006983 6 6 1,000 5,12E-04 9,436E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 5,12E-04 9,342E-03 ! bone mineralization GO:0030282 6 6 1,000 5,12E-04 9,251E-03 GO:0031214|biomineral formation, ! regulation of bone resorption GO:0045124 6 6 1,000 5,12E-04 9,161E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 5,12E-04 9,073E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 5,12E-04 8,986E-03 ! negative regulation of BMP signaling pathway GO:0030514 6 6 1,000 5,12E-04 8,902E-03 ! localization within membrane GO:0051668 6 6 1,000 5,12E-04 8,818E-03 ! energy reserve metabolic process GO:0006112 28 27 2,000 5,203E-04 8,879E-03 ! learning or memory GO:0007611 28 27 2,000 5,203E-04 8,797E-03 ! developmental growth GO:0048589 28 28 2,000 5,803E-04 9,723E-03 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 5,803E-04 9,636E-03 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 5,992E-04 9,86E-03 ! striated muscle tissue development GO:0014706 69 67 3,000 6,345E-04 0,01034817 ! negative regulation of cell differentiation GO:0045596 68 67 3,000 6,345E-04 0,0102574 ! positive regulation of cell cycle GO:0045787 29 29 2,000 6,446E-04 0,01033076 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 6,446E-04 0,01024171 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 6,446E-04 0,01015417 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! positive regulation of protein transport GO:0051222 29 29 2,000 6,446E-04 0,01006812 ! response to UV GO:0009411 29 29 2,000 6,446E-04 9,984E-03 ! response to radiation GO:0009314 70 68 3,000 6,712E-04 0,01030918 ! regulation of cell size GO:0008361 68 68 3,000 6,712E-04 0,01022398 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 7,095E-04 0,01071805 ! establishment of organelle localization GO:0051656 31 30 2,000 7,133E-04 0,01068777 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 7,141E-04 0,01061292 ! visual behavior GO:0007632 7 7 1,000 7,141E-04 0,01052802 GO:0008542|visual learning, ! digestive system development GO:0055123 7 7 1,000 7,141E-04 0,01044446 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! cell differentiation in spinal cord GO:0021515 7 7 1,000 7,141E-04 0,01036222 ! cranial nerve development GO:0021545 7 7 1,000 7,141E-04 0,01028127 ! autonomic nervous system development GO:0048483 7 7 1,000 7,141E-04 0,01020157 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 7,141E-04 0,0101231 ! growth GO:0040007 70 70 3,000 7,493E-04 0,01054127 ! camera-type eye development GO:0043010 31 31 2,000 7,865E-04 0,01098061 ! extracellular matrix organization GO:0030198 31 31 2,000 7,865E-04 0,01089805 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 7,865E-04 0,01081672 ! negative regulation of cell growth GO:0030308 32 32 2,000 8,642E-04 0,01179841 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 8,642E-04 0,01171165 ! kidney development GO:0001822 32 32 2,000 8,642E-04 0,01162617 ! negative regulation of cell size GO:0045792 33 33 2,000 9,467E-04 0,01264375 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 9,485E-04 0,01257589 ! negative regulation of microtubule depolymerization GO:0007026 8 8 1,000 9,485E-04 0,01248606 GO:0031114|regulation of microtubule depolymerization, ! fructose metabolic process GO:0006000 8 8 1,000 9,485E-04 0,01239751 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 9,485E-04 0,0123102 ! T cell homeostasis GO:0043029 8 8 1,000 9,485E-04 0,01222412 ! peptidyl-serine modification GO:0018209 8 8 1,000 9,485E-04 0,01213923 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 1,000 9,485E-04 0,01205551 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 9,485E-04 0,01197294 ! regulation of angiogenesis GO:0045765 35 34 2,000 1,034E-03 0,01296464 ! regulation of bone remodeling GO:0046850 34 34 2,000 1,034E-03 0,01287704 ! cellular polysaccharide metabolic process GO:0044264 35 34 2,000 1,034E-03 0,01279061 ! regulation of lipid metabolic process GO:0019216 34 34 2,000 1,034E-03 0,01270534 ! regulation of tissue remodeling GO:0034103 35 35 2,000 1,126E-03 0,01374753 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,215E-03 0,01473036 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,215E-03 0,01463408 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,215E-03 0,01453905 ! cerebral cortex development GO:0021987 9 9 1,000 1,215E-03 0,01444525 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,215E-03 0,01435266 GO:0060675|ureteric bud morphogenesis, ! regulation of dephosphorylation GO:0035303 9 9 1,000 1,215E-03 0,01426124 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 1,215E-03 0,01417098 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,215E-03 0,01408185 ! histone acetylation GO:0016573 9 9 1,000 1,215E-03 0,01399384 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 1,215E-03 0,01390692 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,215E-03 0,01382108 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 1,000 1,215E-03 0,01373628 ! tube development GO:0035295 83 81 3,000 1,297E-03 0,01457392 ! meiosis GO:0007126 37 37 2,000 1,326E-03 0,01481295 GO:0051327|M phase of meiotic cell cycle, ! eye development GO:0001654 37 37 2,000 1,326E-03 0,01472371 ! negative regulation of growth GO:0045926 37 37 2,000 1,326E-03 0,01463555 ! ncRNA processing GO:0034470 83 83 3,000 1,42E-03 0,01557952 ! meiotic cell cycle GO:0051321 38 38 2,000 1,434E-03 0,01563727 ! regulation of homeostatic process GO:0032844 38 38 2,000 1,434E-03 0,01554529 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 1,513E-03 0,01630535 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,513E-03 0,01621055 ! glial cell development GO:0021782 10 10 1,000 1,513E-03 0,01611685 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 1,513E-03 0,01602423 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,513E-03 0,01593266 ! centrosome cycle GO:0007098 10 10 1,000 1,513E-03 0,01584213 ! induction of apoptosis via death domain receptors GO:0008625 10 10 1,000 1,513E-03 0,01575263 ! epidermis morphogenesis GO:0048730 10 10 1,000 1,513E-03 0,01566413 ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 1,513E-03 0,01557662 ! neuromuscular junction development GO:0007528 10 10 1,000 1,513E-03 0,01549009 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 1,513E-03 0,01540451 ! regulation of BMP signaling pathway GO:0030510 10 10 1,000 1,513E-03 0,01531987 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 1,000 1,513E-03 0,01523615 ! lymphocyte homeostasis GO:0002260 10 10 1,000 1,513E-03 0,01515334 ! nerve development GO:0021675 10 10 1,000 1,513E-03 0,01507143 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 1,513E-03 0,01499041 ! gut development GO:0048565 10 10 1,000 1,513E-03 0,01491024 ! embryonic organ morphogenesis GO:0048562 10 10 1,000 1,513E-03 0,01483093 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,513E-03 0,01475246 ! protein stabilization GO:0050821 10 10 1,000 1,513E-03 0,01467482 ! regulation of cellular localization GO:0060341 86 85 3,000 1,551E-03 0,01497017 ! DNA catabolic process GO:0006308 41 40 2,000 1,666E-03 0,01598753 ! myeloid cell differentiation GO:0030099 42 40 2,000 1,666E-03 0,01590469 ! organelle localization GO:0051640 41 40 2,000 1,666E-03 0,01582271 ! positive regulation of transferase activity GO:0051347 91 88 3,000 1,764E-03 0,01667116 GO:0033674|positive regulation of kinase activity, ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 1,842E-03 0,0173213 ! skin development GO:0043588 11 11 1,000 1,842E-03 0,01723337 ! protein amino acid acetylation GO:0006473 11 11 1,000 1,842E-03 0,01714634 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 1,000 1,842E-03 0,01706017 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 1,842E-03 0,01697487 ! mitotic spindle organization GO:0007052 11 11 1,000 1,842E-03 0,01689042 ! apoptotic nuclear changes GO:0030262 11 11 1,000 1,842E-03 0,01680681 ! G1/S transition checkpoint GO:0031575 12 11 1,000 1,842E-03 0,01672401 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,842E-03 0,01664203 ! proximal/distal pattern formation GO:0009954 11 11 1,000 1,842E-03 0,01656085 ! forebrain development GO:0030900 43 42 2,000 1,919E-03 0,01717181 ! reproductive structure development GO:0048608 43 43 2,000 2,055E-03 0,01829488 ! homeostasis of number of cells GO:0048872 44 43 2,000 2,055E-03 0,01820693 ! tissue morphogenesis GO:0048729 94 93 3,000 2,162E-03 0,01906243 ! negative regulation of organelle organization GO:0010639 45 44 2,000 2,196E-03 0,01927339 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 2,202E-03 0,01923517 ! microtubule organizing center organization GO:0031023 12 12 1,000 2,202E-03 0,01914444 GO:0051297|centrosome organization, ! osteoblast differentiation GO:0001649 12 12 1,000 2,202E-03 0,01905456 ! pallium development GO:0021543 13 12 1,000 2,202E-03 0,01896552 ! regulation of chromosome organization GO:0033044 12 12 1,000 2,202E-03 0,0188773 ! somitogenesis GO:0001756 13 12 1,000 2,202E-03 0,01878991 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 2,202E-03 0,01870332 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 2,202E-03 0,01861752 ! blood vessel development GO:0001568 95 94 3,000 2,248E-03 0,01891925 ! vasculature development GO:0001944 97 96 3,000 2,428E-03 0,02034079 ! tube morphogenesis GO:0035239 47 46 2,000 2,496E-03 0,02081882 ! regulation of membrane potential GO:0042391 46 46 2,000 2,496E-03 0,02072504 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 2,593E-03 0,02142819 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 2,593E-03 0,02133253 ! ureteric bud development GO:0001657 13 13 1,000 2,593E-03 0,02123772 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,593E-03 0,02114374 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 2,593E-03 0,0210506 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 2,593E-03 0,02095827 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 2,593E-03 0,02086675 ! cell-cell junction organization GO:0045216 13 13 1,000 2,593E-03 0,02077603 ! blastocyst development GO:0001824 13 13 1,000 2,593E-03 0,02068609 ! anti-apoptosis GO:0006916 100 99 3,000 2,716E-03 0,02157831 ! hemopoiesis GO:0030097 104 100 3,000 2,817E-03 0,02228524 ! skeletal muscle tissue development GO:0007519 50 49 2,000 2,993E-03 0,0235708 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 2,993E-03 0,0234705 ! neuron fate commitment GO:0048663 14 14 1,000 3,014E-03 0,02353352 ! protein amino acid acylation GO:0043543 14 14 1,000 3,014E-03 0,02343423 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 3,171E-03 0,02455252 ! rRNA metabolic process GO:0016072 51 51 2,000 3,355E-03 0,0258711 GO:0006364|rRNA processing, ! protein import into nucleus, translocation GO:0000060 15 15 1,000 3,464E-03 0,02660101 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 3,464E-03 0,02649063 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 3,464E-03 0,02638117 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 3,464E-03 0,0262726 ! striated muscle cell differentiation GO:0051146 16 15 1,000 3,464E-03 0,02616493 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 3,464E-03 0,02605813 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 3,464E-03 0,0259522 ! leukocyte homeostasis GO:0001776 15 15 1,000 3,464E-03 0,02584713 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 3,464E-03 0,02574291 ! cell fate commitment GO:0045165 52 52 2,000 3,546E-03 0,02624412 ! response to hypoxia GO:0001666 53 53 2,000 3,743E-03 0,02759362 ! regulation of T cell activation GO:0050863 53 53 2,000 3,743E-03 0,02748369 ! positive regulation of mitosis GO:0045840 16 16 1,000 3,944E-03 0,02884456 GO:0051785|positive regulation of nuclear division, ! segmentation GO:0035282 17 16 1,000 3,944E-03 0,02873055 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 3,944E-03 0,02861743 ! cell fate specification GO:0001708 16 16 1,000 3,944E-03 0,02850521 ! cellular response to nutrient levels GO:0031669 16 16 1,000 3,944E-03 0,02839386 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 3,944E-03 0,02828338 ! response to oxygen levels GO:0070482 55 54 2,000 3,947E-03 0,02819451 ! reproductive developmental process GO:0003006 56 56 2,000 4,375E-03 0,03113011 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 4,453E-03 0,03156548 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 1,000 4,453E-03 0,03144454 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 4,453E-03 0,03132452 ! negative regulation of cell development GO:0010721 18 17 1,000 4,453E-03 0,03120542 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 4,453E-03 0,03108722 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 4,453E-03 0,03096991 ! pigmentation GO:0043473 17 17 1,000 4,453E-03 0,03085348 ! embryonic organ development GO:0048568 17 17 1,000 4,453E-03 0,03073792 ! liver development GO:0001889 17 17 1,000 4,453E-03 0,03062323 ! regulation of cell projection organization GO:0031344 19 18 1,000 4,991E-03 0,03419403 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 4,991E-03 0,03406739 ! negative regulation of MAP kinase activity GO:0043407 18 18 1,000 4,991E-03 0,03394168 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 4,991E-03 0,03381689 ! regulation of microtubule-based process GO:0032886 18 18 1,000 4,991E-03 0,03369302 ! negative regulation of catabolic process GO:0009895 18 18 1,000 4,991E-03 0,03357005 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 5,068E-03 0,03396235 ! DNA damage checkpoint GO:0000077 19 19 1,000 5,557E-03 0,03710762 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 5,557E-03 0,03697366 ! regulation of protein stability GO:0031647 19 19 1,000 5,557E-03 0,03684066 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 5,557E-03 0,03670862 ! response to heat GO:0009408 19 19 1,000 5,557E-03 0,03657751 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 5,823E-03 0,03819307 GO:0060429|epithelium development, ! regulation of lymphocyte activation GO:0051249 62 62 2,000 5,823E-03 0,03805763 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 6,151E-03 0,0400598 ! neural tube development GO:0021915 21 20 1,000 6,151E-03 0,03991875 ! nucleus organization GO:0006997 20 20 1,000 6,151E-03 0,03977868 ! regulation of B cell activation GO:0050864 20 20 1,000 6,151E-03 0,0396396 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 6,643E-03 0,04265949 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 6,773E-03 0,04334456 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 1,000 6,773E-03 0,04319458 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! DNA integrity checkpoint GO:0031570 21 21 1,000 6,773E-03 0,04304563 ! negative regulation of protein transport GO:0051224 21 21 1,000 6,773E-03 0,04289771 ! polysaccharide metabolic process GO:0005976 69 66 2,000 6,931E-03 0,04374556 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 6,931E-03 0,04359625 ! Ras protein signal transduction GO:0007265 69 67 2,000 7,226E-03 0,04529815 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 7,423E-03 0,04637293 GO:0090047|positive regulation of transcription regulator activity, ! sister chromatid segregation GO:0000819 22 22 1,000 7,423E-03 0,04621627 ! cell junction organization GO:0034330 23 22 1,000 7,423E-03 0,04606066 ! embryonic skeletal system development GO:0048706 22 22 1,000 7,423E-03 0,04590609 ! cell chemotaxis GO:0060326 23 22 1,000 7,423E-03 0,04575256 GO:0030595|leukocyte chemotaxis, ! erythrocyte differentiation GO:0030218 23 22 1,000 7,423E-03 0,04560005 ! cytokinesis GO:0000910 23 22 1,000 7,423E-03 0,04544856 ! regionalization GO:0003002 70 69 2,000 7,839E-03 0,04783602 ! regulation of leukocyte activation GO:0002694 69 69 2,000 7,839E-03 0,04767814 ! epithelial cell differentiation GO:0030855 23 23 1,000 8,099E-03 0,04910084 ! negative regulation of protein complex disassembly GO:0043242 23 23 1,000 8,099E-03 0,04893986 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 8,099E-03 0,04877992 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 8,099E-03 0,04862103 ! endocrine system development GO:0035270 23 23 1,000 8,099E-03 0,04846317 ! calcium-mediated signaling GO:0019722 23 23 1,000 8,099E-03 0,04830633 ! Rho protein signal transduction GO:0007266 24 23 1,000 8,099E-03 0,04815051 ! positive regulation of transport GO:0051050 71 70 2,000 8,156E-03 0,0483328 ! wound healing GO:0042060 74 70 2,000 8,156E-03 0,04817789 ! regulation of cell migration GO:0030334 71 71 2,000 8,481E-03 0,0499373 ! ribosome biogenesis GO:0042254 71 71 2,000 8,481E-03 0,04977826 ! negative regulation of signal transduction GO:0009968 71 71 2,000 8,481E-03 0,04962023 ! regulation of cell activation GO:0050865 71 71 2,000 8,481E-03 0,04946321 ! glucose homeostasis GO:0042593 24 24 1,000 8,802E-03 0,05117524 GO:0033500|carbohydrate homeostasis, ! erythrocyte homeostasis GO:0034101 25 24 1,000 8,802E-03 0,05101431 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 8,802E-03 0,05085439 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 8,813E-03 0,05075989 ! sensory organ development GO:0007423 72 72 2,000 8,813E-03 0,05060176 ! cellular component disassembly GO:0022411 26 25 1,000 9,532E-03 0,0545562 ! positive regulation of DNA binding GO:0043388 26 25 1,000 9,532E-03 0,05438729 ! negative regulation of cell communication GO:0010648 76 76 2,000 0,0102197 0,05813241 ! positive regulation of binding GO:0051099 27 26 1,000 0,01028741 0,05833752 ! glycolysis GO:0006096 26 26 1,000 0,01028741 0,05815857 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 0,01028741 0,05798072 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01028741 0,05780395 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01028741 0,05762825 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01028741 0,05745362 ! synapse organization GO:0050808 26 26 1,000 0,01028741 0,05728004 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,0105905 0,05879005 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01106878 0,06126053 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! cell growth GO:0016049 27 27 1,000 0,01106878 0,06107712 ! regulation of locomotion GO:0040012 79 79 2,000 0,01135543 0,06247182 ! regulation of cell motion GO:0051270 79 79 2,000 0,01135543 0,06228589 ! histone modification GO:0016570 28 28 1,000 0,01187558 0,06494569 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01187558 0,06475354 ! leukocyte migration GO:0050900 30 29 1,000 0,0127075 0,06908534 ! tRNA processing GO:0008033 29 29 1,000 0,0127075 0,06888215 ! covalent chromatin modification GO:0016569 29 29 1,000 0,0127075 0,06868015 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,01297935 0,06994425 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01356423 0,07288304 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 1,000 0,01356423 0,07267117 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,01356423 0,07246053 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01356423 0,07225111 ! regulation of ossification GO:0030278 30 30 1,000 0,01356423 0,07204289 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 0,01428037 0,07562854 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,01428037 0,07541184 ! regulation of translational initiation GO:0006446 31 31 1,000 0,01444546 0,07606566 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01444546 0,07584895 ! negative regulation of cytoskeleton organization GO:0051494 32 31 1,000 0,01444546 0,07563347 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01444546 0,07541921 ! regulation of DNA replication GO:0006275 32 31 1,000 0,01444546 0,07520616 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,01444546 0,07499432 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01444546 0,07478366 ! muscle fiber development GO:0048747 32 32 1,000 0,01535087 0,07924835 ! glucose catabolic process GO:0006007 32 32 1,000 0,01535087 0,07902699 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01535087 0,07880686 ! cell maturation GO:0048469 32 32 1,000 0,01535087 0,07858795 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01535087 0,07837025 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01535087 0,07815376 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01535087 0,07793846 ! brain development GO:0007420 91 90 2,000 0,01612696 0,08165382 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,01628017 0,08220373 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,01628017 0,08197913 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 0,01709852 0,0858653 ! muscle cell differentiation GO:0042692 35 34 1,000 0,01723305 0,08630576 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,01723305 0,08607187 ! viral reproduction GO:0016032 34 34 1,000 0,01723305 0,08583924 ! pattern specification process GO:0007389 96 94 2,000 0,0181024 0,08992646 ! epidermis development GO:0008544 94 94 2,000 0,0181024 0,08968472 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01820922 0,08997209 ! regulation of mitosis GO:0007088 37 36 1,000 0,01920837 0,09465514 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 1,000 0,01920837 0,09440272 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,01920837 0,09415165 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01920837 0,09390191 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 0,01920837 0,09365349 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,01920837 0,09340639 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01920837 0,09316058 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,02020748 0,09774907 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02023021 0,0976028 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,02023021 0,09734797 GO:0090046|regulation of transcription regulator activity, ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,02023021 0,09709446 ! ectoderm development GO:0007398 99 99 2,000 0,02075408 0,09935007 ! chromosome segregation GO:0007059 38 38 1,000 0,02127445 0,10157721 ! hexose catabolic process GO:0019320 38 38 1,000 0,02127445 0,10131474 ! RNA elongation GO:0006354 38 38 1,000 0,02127445 0,10105362 ! axon guidance GO:0007411 39 38 1,000 0,02127445 0,10079384 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,02130883 0,10069786 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,02234079 0,10530456 ! response to unfolded protein GO:0006986 39 39 1,000 0,02234079 0,10503593 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,02234079 0,10476866 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,02234079 0,10450275 ! developmental maturation GO:0021700 39 39 1,000 0,02234079 0,10423818 ! limb development GO:0060173 39 39 1,000 0,02234079 0,10397496 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! positive regulation of cell motion GO:0051272 39 39 1,000 0,02234079 0,10371305 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,02342896 0,10849141 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,02453867 0,1133453 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 0,02453867 0,11306194 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,02453867 0,11277999 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,02566964 0,11768444 ! response to protein stimulus GO:0051789 42 42 1,000 0,02566964 0,11739242 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,02566964 0,11710184 ! mitochondrion organization GO:0007005 44 43 1,000 0,02682158 0,12205475 ! alcohol catabolic process GO:0046164 43 43 1,000 0,02682158 0,12175412 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,02682158 0,12145497 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,02799422 0,1264543 ! protein import into nucleus GO:0006606 44 44 1,000 0,02799422 0,12614512 ! regulation of DNA binding GO:0051101 47 45 1,000 0,02918729 0,13120043 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,02918729 0,13088121 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,02918729 0,13056353 ! nuclear import GO:0051170 45 45 1,000 0,02918729 0,1302474 ! rRNA transcription GO:0009303 5 5 0,000 0,02945195 0,13111097 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02945195 0,13079504 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02945195 0,13048063 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02945195 0,13016773 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02945195 0,12985632 ! reproductive cellular process GO:0048610 5 5 0,000 0,02945195 0,1295464 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,02945195 0,12923796 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02945195 0,12893098 ! metencephalon development GO:0022037 5 5 0,000 0,02945195 0,12862546 ! water transport GO:0006833 5 5 0,000 0,02945195 0,12832138 GO:0042044|fluid transport, ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02945195 0,12801873 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02945195 0,12771751 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02945195 0,12741771 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02945195 0,1271193 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02945195 0,1268223 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02945195 0,12652667 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02945195 0,12623243 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02945195 0,12593954 ! CTP metabolic process GO:0046036 5 5 0,000 0,02945195 0,12564802 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02945195 0,12535784 ! GTP metabolic process GO:0046039 5 5 0,000 0,02945195 0,12506899 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02945195 0,12478148 ! mRNA stabilization GO:0048255 5 5 0,000 0,02945195 0,12449528 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02945195 0,1242104 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02945195 0,12392681 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02945195 0,12364452 ! social behavior GO:0035176 5 5 0,000 0,02945195 0,12336351 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02945195 0,12308377 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02945195 0,1228053 ! memory GO:0007613 5 5 0,000 0,02945195 0,12252809 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02945195 0,12225212 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02945195 0,1219774 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02945195 0,12170391 ! response to lipid GO:0033993 5 5 0,000 0,02945195 0,12143164 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02945195 0,12116059 ! hippocampus development GO:0021766 6 5 0,000 0,02945195 0,12089074 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02945195 0,1206221 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02945195 0,12035464 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02945195 0,12008837 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02945195 0,11982327 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02945195 0,11955935 ! heart looping GO:0001947 5 5 0,000 0,02945195 0,11929658 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02945195 0,11903496 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02945195 0,11877449 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02945195 0,11851516 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02945195 0,11825696 ! pH reduction GO:0045851 5 5 0,000 0,02945195 0,11799988 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02945195 0,11774391 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02945195 0,11748905 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02945195 0,1172353 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02945195 0,11698264 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02945195 0,11673106 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02945195 0,11648056 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02945195 0,11623114 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02945195 0,11598278 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02945195 0,11573549 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02945195 0,11548924 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02945195 0,11524404 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02945195 0,11499988 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02945195 0,11475675 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02945195 0,11451465 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02945195 0,11427356 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02945195 0,11403349 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02945195 0,11379443 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02945195 0,11355637 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02945195 0,1133193 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02945195 0,11308321 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02945195 0,11284811 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02945195 0,11261399 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02945195 0,11238083 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02945195 0,11214864 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02945195 0,11191741 ! response to ATP GO:0033198 5 5 0,000 0,02945195 0,11168713 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02945195 0,11145779 ! regulation of appetite GO:0032098 5 5 0,000 0,02945195 0,11122939 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02945195 0,11100193 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02945195 0,11077539 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02945195 0,11054978 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02945195 0,11032509 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02945195 0,1101013 ! receptor clustering GO:0043113 5 5 0,000 0,02945195 0,10987843 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02945195 0,10965645 ! fear response GO:0042596 5 5 0,000 0,02945195 0,10943537 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02945195 0,10921518 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02945195 0,10899587 ! retinol metabolic process GO:0042572 5 5 0,000 0,02945195 0,10877744 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02945195 0,10855989 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02945195 0,1083432 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02945195 0,10812738 ! parturition GO:0007567 5 5 0,000 0,02945195 0,10791241 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02945195 0,1076983 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02945195 0,10748504 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02945195 0,10727261 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02945195 0,10706103 ! protein heterooligomerization GO:0051291 5 5 0,000 0,02945195 0,10685028 ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02945195 0,10664036 ! response to UV-B GO:0010224 5 5 0,000 0,02945195 0,10643126 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02945195 0,10622298 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02945195 0,10601551 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02945195 0,10580886 ! interaction with symbiont GO:0051702 5 5 0,000 0,02945195 0,105603 ! cellular extravasation GO:0045123 5 5 0,000 0,02945195 0,10539795 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02945195 0,10519369 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02945195 0,10499022 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02945195 0,10478754 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02945195 0,10458563 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02945195 0,10438451 ! response to amine stimulus GO:0014075 5 5 0,000 0,02945195 0,10418415 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02945195 0,10398457 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02945195 0,10378574 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02945195 0,10358768 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02945195 0,10339037 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02945195 0,10319381 ! neuron recognition GO:0008038 5 5 0,000 0,02945195 0,10299799 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02945195 0,10280292 ! decidualization GO:0046697 5 5 0,000 0,02945195 0,10260859 ! hair follicle maturation GO:0048820 5 5 0,000 0,02945195 0,10241499 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02945195 0,10222212 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02945195 0,10202997 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02945195 0,10183854 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02945195 0,10164783 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02945195 0,10145784 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02945195 0,10126855 ! postreplication repair GO:0006301 5 5 0,000 0,02945195 0,10107997 ! cellular pigmentation GO:0033059 5 5 0,000 0,02945195 0,10089209 ! histone methylation GO:0016571 5 5 0,000 0,02945195 0,1007049 ! DNA methylation GO:0006306 5 5 0,000 0,02945195 0,10051841 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02945195 0,10033261 ! T cell lineage commitment GO:0002360 5 5 0,000 0,02945195 0,1001475 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02945195 0,09996306 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02945195 0,09977931 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02945195 0,09959623 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02945195 0,09941382 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02945195 0,09923207 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02945195 0,09905099 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02945195 0,09887057 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02945195 0,09869081 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02945195 0,09851169 ! sterol catabolic process GO:0016127 5 5 0,000 0,02945195 0,09833323 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02945195 0,09815541 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02945195 0,09797824 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02945195 0,0978017 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02945195 0,0976258 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02945195 0,09745053 ! zymogen activation GO:0031638 5 5 0,000 0,02945195 0,09727588 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02945195 0,09710187 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02945195 0,09692847 GO:0002820|negative regulation of adaptive immune response, ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02945195 0,09675569 ! nucleosome positioning GO:0016584 5 5 0,000 0,02945195 0,09658353 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02945195 0,09641198 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02945195 0,09624103 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02945195 0,0960707 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02945195 0,09590096 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02945195 0,09573182 ! NADPH regeneration GO:0006740 5 5 0,000 0,02945195 0,09556328 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02945195 0,09539533 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02945195 0,09522797 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02945195 0,0950612 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02945195 0,09489501 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02945195 0,09472939 ! sarcomere organization GO:0045214 5 5 0,000 0,02945195 0,09456436 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02945195 0,0943999 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02945195 0,09423601 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02945195 0,09407269 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02945195 0,09390994 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02945195 0,09374774 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02945195 0,09358611 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02945195 0,09342503 ! spleen development GO:0048536 5 5 0,000 0,02945195 0,09326451 ! male genitalia development GO:0030539 5 5 0,000 0,02945195 0,09310453 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02945195 0,09294511 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02945195 0,09278623 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02945195 0,09262789 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02945195 0,09247009 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02945195 0,09231283 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02945195 0,0921561 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02945195 0,0919999 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02945195 0,09184424 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02945195 0,09168909 ! ATP catabolic process GO:0006200 5 5 0,000 0,02945195 0,09153447 ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02945195 0,09138038 ! blastocyst formation GO:0001825 5 5 0,000 0,02945195 0,0912268 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02945195 0,09107373 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02945195 0,09092118 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02945195 0,09076914 ! activation of innate immune response GO:0002218 5 5 0,000 0,02945195 0,0906176 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02945195 0,09046657 ! catecholamine transport GO:0051937 5 5 0,000 0,02945195 0,09031605 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02945195 0,09016602 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02945195 0,09001649 ! muscle adaptation GO:0043500 5 5 0,000 0,02945195 0,08986746 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02945195 0,08971891 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02945195 0,08957086 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02945195 0,0894233 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02945195 0,08927622 ! defense response to fungus GO:0050832 5 5 0,000 0,02945195 0,08912963 ! lysogeny GO:0030069 5 5 0,000 0,02945195 0,08898351 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02945195 0,08883788 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02945195 0,08869272 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02945195 0,08854803 ! response to nicotine GO:0035094 5 5 0,000 0,02945195 0,08840382 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02945195 0,08826007 ! mitochondrion localization GO:0051646 5 5 0,000 0,02945195 0,08811679 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02945195 0,08797398 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,03040051 0,09066042 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,03040051 0,09051396 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,03040051 0,09036797 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,03163361 0,09388204 ! regulation of blood pressure GO:0008217 48 47 1,000 0,03163361 0,09373111 ! sex differentiation GO:0007548 47 47 1,000 0,03163361 0,09358066 ! regulation of catabolic process GO:0009894 48 47 1,000 0,03163361 0,09343069 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,03288633 0,09697521 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,03288633 0,0968203 ! protein localization in nucleus GO:0034504 48 48 1,000 0,03288633 0,09666588 ! DNA recombination GO:0006310 48 48 1,000 0,03288633 0,09651196 ! leukocyte differentiation GO:0002521 50 49 1,000 0,0341584 0,10008574 ! response to nutrient GO:0007584 49 49 1,000 0,0341584 0,09992688 ! regulation of ligase activity GO:0051340 50 49 1,000 0,0341584 0,09976851 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03523995 0,10276459 ! axon extension GO:0048675 7 6 0,000 0,03523995 0,10260224 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03523995 0,10244041 ! tRNA modification GO:0006400 6 6 0,000 0,03523995 0,10227909 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03523995 0,10211827 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03523995 0,10195796 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03523995 0,10179815 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03523995 0,10163884 ! virus-host interaction GO:0019048 6 6 0,000 0,03523995 0,10148003 ! regulation of S phase GO:0033261 6 6 0,000 0,03523995 0,10132171 ! myotube differentiation GO:0014902 6 6 0,000 0,03523995 0,10116389 ! bone remodeling GO:0046849 6 6 0,000 0,03523995 0,10100656 ! N-glycan processing GO:0006491 6 6 0,000 0,03523995 0,10084972 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03523995 0,10069336 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03523995 0,10053749 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03523995 0,1003821 ! RNA methylation GO:0001510 6 6 0,000 0,03523995 0,10022719 ! cartilage condensation GO:0001502 7 6 0,000 0,03523995 0,10007276 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,03523995 0,0999188 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,03523995 0,09976531 ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03523995 0,0996123 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03523995 0,09945975 ! androgen metabolic process GO:0008209 6 6 0,000 0,03523995 0,09930767 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03523995 0,09915606 ! limbic system development GO:0021761 7 6 0,000 0,03523995 0,09900491 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03523995 0,09885421 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,03523995 0,09870398 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03523995 0,0985542 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03523995 0,09840488 ! pathogenesis GO:0009405 6 6 0,000 0,03523995 0,098256 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03523995 0,09810758 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03523995 0,09795961 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03523995 0,09781208 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03523995 0,09766499 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03523995 0,09751835 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03523995 0,09737214 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03523995 0,09722638 ! arginine metabolic process GO:0006525 6 6 0,000 0,03523995 0,09708105 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03523995 0,09693615 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03523995 0,09679168 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03523995 0,09664765 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03523995 0,09650404 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03523995 0,09636086 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03523995 0,0962181 ! V(D)J recombination GO:0033151 6 6 0,000 0,03523995 0,09607577 ! focal adhesion formation GO:0048041 7 6 0,000 0,03523995 0,09593385 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03523995 0,09579236 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03523995 0,09565128 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03523995 0,09551062 ! regulation of heart rate GO:0002027 6 6 0,000 0,03523995 0,09537037 ! lipid digestion GO:0044241 6 6 0,000 0,03523995 0,09523053 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03523995 0,0950911 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03523995 0,09495207 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03523995 0,09481346 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03523995 0,09467525 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,03523995 0,09453744 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03523995 0,09440003 ! ruffle organization GO:0031529 6 6 0,000 0,03523995 0,09426302 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03523995 0,0941264 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03523995 0,09399019 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03523995 0,09385436 ! L-amino acid transport GO:0015807 6 6 0,000 0,03523995 0,09371893 ! rRNA modification GO:0000154 6 6 0,000 0,03523995 0,09358389 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03523995 0,09344924 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03523995 0,09331497 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03523995 0,09318109 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03523995 0,09304759 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,03523995 0,09291448 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03523995 0,09278174 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03523995 0,09264939 ! regulation of organ growth GO:0046620 6 6 0,000 0,03523995 0,09251741 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03523995 0,0923858 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03523995 0,09225457 ! response to dsRNA GO:0043331 6 6 0,000 0,03523995 0,09212372 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03523995 0,09199323 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03523995 0,09186311 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03523995 0,09173336 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03523995 0,09160398 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03523995 0,09147496 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03523995 0,0913463 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03523995 0,091218 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03523995 0,09109007 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03523995 0,09096249 ! erythrocyte development GO:0048821 6 6 0,000 0,03523995 0,09083527 ! renal water homeostasis GO:0003091 6 6 0,000 0,03523995 0,09070841 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03523995 0,0905819 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03523995 0,09045574 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03523995 0,09032993 ! ribosome assembly GO:0042255 6 6 0,000 0,03523995 0,09020447 ! diencephalon development GO:0021536 6 6 0,000 0,03523995 0,09007936 ! fucose catabolic process GO:0019317 6 6 0,000 0,03523995 0,0899546 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03523995 0,08983018 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03523995 0,0897061 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03523995 0,08958237 ! regulation of cell division GO:0051302 6 6 0,000 0,03523995 0,08945898 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03523995 0,08933593 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03523995 0,08921321 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03523995 0,08909084 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03523995 0,08896879 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03523995 0,08884709 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03523995 0,08872571 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03523995 0,08860466 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03523995 0,08848395 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03523995 0,08836356 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03523995 0,0882435 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03523995 0,08812377 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03523995 0,08800436 ! thymus development GO:0048538 6 6 0,000 0,03523995 0,08788528 ! lymph node development GO:0048535 6 6 0,000 0,03523995 0,08776651 ! organic cation transport GO:0015695 6 6 0,000 0,03523995 0,08764807 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03523995 0,08752994 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,03523995 0,08741214 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03523995 0,08729465 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03523995 0,08717748 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03523995 0,08706062 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03523995 0,08694407 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03523995 0,08682783 ! alditol metabolic process GO:0019400 6 6 0,000 0,03523995 0,08671191 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03523995 0,08659629 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03523995 0,08648098 ! maternal placenta development GO:0001893 6 6 0,000 0,03523995 0,08636598 ! regulation of embryonic development GO:0045995 6 6 0,000 0,03523995 0,08625129 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03523995 0,0861369 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,03544956 0,08653448 ! negative regulation of transport GO:0051051 51 50 1,000 0,03544956 0,08642002 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,03544956 0,08630586 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,03544956 0,086192 ! transcription initiation GO:0006352 50 50 1,000 0,03544956 0,08607844 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,03544956 0,08596518 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,03808809 0,09224225 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,03808809 0,0921212 ! tRNA metabolic process GO:0006399 53 53 1,000 0,03943496 0,09525377 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,03943496 0,09512909 ! hormone metabolic process GO:0042445 55 54 1,000 0,04079988 0,09829305 ! respiratory burst GO:0045730 7 7 0,000 0,04099426 0,0986324 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04099426 0,09850381 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04099426 0,09837555 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04099426 0,09824762 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04099426 0,09812003 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04099426 0,09799277 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04099426 0,09786583 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04099426 0,09773923 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04099426 0,09761295 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04099426 0,097487 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04099426 0,09736137 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04099426 0,09723606 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04099426 0,09711108 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04099426 0,09698642 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04099426 0,09686208 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04099426 0,09673806 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04099426 0,09661435 ! axis specification GO:0009798 7 7 0,000 0,04099426 0,09649096 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04099426 0,09636789 ! startle response GO:0001964 7 7 0,000 0,04099426 0,09624512 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04099426 0,09612267 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04099426 0,09600054 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04099426 0,09587871 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04099426 0,09575719 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04099426 0,09563598 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04099426 0,09551507 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04099426 0,09539447 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04099426 0,09527418 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04099426 0,09515418 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04099426 0,09503449 ! protein targeting to ER GO:0045047 8 7 0,000 0,04099426 0,0949151 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04099426 0,09479601 ! endoderm development GO:0007492 7 7 0,000 0,04099426 0,09467722 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04099426 0,09455873 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04099426 0,09444053 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,04099426 0,09432262 ! response to hexose stimulus GO:0009746 7 7 0,000 0,04099426 0,09420501 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04099426 0,0940877 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04099426 0,09397067 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04099426 0,09385394 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04099426 0,0937375 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04099426 0,09362134 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04099426 0,09350547 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04099426 0,09338989 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04099426 0,0932746 ! response to X-ray GO:0010165 7 7 0,000 0,04099426 0,09315958 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04099426 0,09304485 ! UV protection GO:0009650 7 7 0,000 0,04099426 0,09293041 ! DNA integration GO:0015074 7 7 0,000 0,04099426 0,09281624 ! myofibril assembly GO:0030239 7 7 0,000 0,04099426 0,09270236 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04099426 0,09258875 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04099426 0,09247542 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04099426 0,09236237 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04099426 0,0922496 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04099426 0,0921371 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04099426 0,09202487 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04099426 0,09191292 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04099426 0,09180124 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04099426 0,09168983 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04099426 0,09157869 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04099426 0,09146782 ! axon cargo transport GO:0008088 7 7 0,000 0,04099426 0,09135722 ! eating behavior GO:0042755 7 7 0,000 0,04099426 0,09124689 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04099426 0,09113682 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04099426 0,09102701 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04099426 0,09091748 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04099426 0,0908082 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04099426 0,09069919 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04099426 0,09059043 ! induction of an organ GO:0001759 7 7 0,000 0,04099426 0,09048194 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04099426 0,09037371 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04099426 0,09026574 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04099426 0,09015802 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04099426 0,09005056 ! platelet activation GO:0030168 8 7 0,000 0,04099426 0,08994336 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04099426 0,08983641 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04099426 0,08972972 ! natural killer cell activation GO:0030101 7 7 0,000 0,04099426 0,08962328 ! response to gamma radiation GO:0010332 8 7 0,000 0,04099426 0,08951709 ! NADP metabolic process GO:0006739 7 7 0,000 0,04099426 0,08941115 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04099426 0,08930546 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04099426 0,08920003 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04099426 0,08909484 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04099426 0,0889899 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04099426 0,0888852 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04099426 0,08878075 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04099426 0,08867655 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04099426 0,08857259 ! cell-cell recognition GO:0009988 8 7 0,000 0,04099426 0,08846888 ! hormone catabolic process GO:0042447 7 7 0,000 0,04099426 0,08836541 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04099426 0,08826218 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04099426 0,08815919 ! oxygen transport GO:0015671 7 7 0,000 0,04099426 0,08805644 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04099426 0,08795393 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,04099426 0,08785165 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04099426 0,08774962 ! regulation of axon extension GO:0030516 7 7 0,000 0,04099426 0,08764782 ! cell killing GO:0001906 7 7 0,000 0,04099426 0,08754626 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04099426 0,08744493 ! adult feeding behavior GO:0008343 7 7 0,000 0,04099426 0,08734384 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04099426 0,08724298 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04099426 0,08714236 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04099426 0,08704196 ! response to cold GO:0009409 7 7 0,000 0,04099426 0,0869418 ! in utero embryonic development GO:0001701 55 55 1,000 0,04218261 0,08935926 ! regulation of nervous system development GO:0051960 57 56 1,000 0,04358291 0,09221963 ! regulation of binding GO:0051098 60 57 1,000 0,04500051 0,09511002 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04671509 0,09862074 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04671509 0,0985079 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04671509 0,09839532 ! positive regulation of translation GO:0045727 8 8 0,000 0,04671509 0,098283 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04671509 0,09817093 ! superoxide anion generation GO:0042554 8 8 0,000 0,04671509 0,09805912 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04671509 0,09794756 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04671509 0,09783625 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04671509 0,0977252 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04671509 0,0976144 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04671509 0,09750385 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04671509 0,09739356 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,04671509 0,09728351 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04671509 0,09717371 ! zinc ion transport GO:0006829 8 8 0,000 0,04671509 0,09706415 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04671509 0,09695485 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04671509 0,09684579 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04671509 0,09673697 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04671509 0,0966284 ! lipid localization GO:0010876 8 8 0,000 0,04671509 0,09652007 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04671509 0,09641199 ! response to cAMP GO:0051591 8 8 0,000 0,04671509 0,09630414 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04671509 0,09619654 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04671509 0,09608918 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04671509 0,09598206 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04671509 0,09587517 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04671509 0,09576852 ! sensory perception of taste GO:0050909 8 8 0,000 0,04671509 0,09566212 ! organelle fusion GO:0048284 8 8 0,000 0,04671509 0,09555594 ! pancreas development GO:0031016 8 8 0,000 0,04671509 0,09545 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04671509 0,0953443 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,04671509 0,09523883 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04671509 0,0951336 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04671509 0,09502859 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04671509 0,09492382 ! sperm motility GO:0030317 8 8 0,000 0,04671509 0,09481928 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04671509 0,09471497 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04671509 0,09461088 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04671509 0,09450703 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04671509 0,0944034 ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04671509 0,0943 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04671509 0,09419683 ! Golgi organization GO:0007030 8 8 0,000 0,04671509 0,09409388 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04671509 0,09399116 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04671509 0,09388866 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,04671509 0,09378639 ! mannose metabolic process GO:0006013 9 8 0,000 0,04671509 0,09368433 ! NAD metabolic process GO:0019674 8 8 0,000 0,04671509 0,0935825 ! sex determination GO:0007530 8 8 0,000 0,04671509 0,09348089 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04671509 0,09337951 ! plasma membrane fusion GO:0045026 8 8 0,000 0,04671509 0,09327834 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,04671509 0,09317739 ! response to fungus GO:0009620 8 8 0,000 0,04671509 0,09307665 ! stem cell differentiation GO:0048863 8 8 0,000 0,04671509 0,09297614 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04671509 0,09287584 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04671509 0,09277576 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04671509 0,09267589 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04671509 0,09257624 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04671509 0,0924768 ! vasoconstriction GO:0042310 8 8 0,000 0,04671509 0,09237758 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04671509 0,09227857 ! muscle cell development GO:0055001 8 8 0,000 0,04671509 0,09217977 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04671509 0,09208118 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04671509 0,0919828 ! sensory perception of pain GO:0019233 8 8 0,000 0,04671509 0,09188464 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04671509 0,09178668 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04671509 0,09168893 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04671509 0,09159139 ! chromatin silencing GO:0006342 8 8 0,000 0,04671509 0,09149405 ! tissue regeneration GO:0042246 8 8 0,000 0,04671509 0,09139693 ! salivary gland development GO:0007431 8 8 0,000 0,04671509 0,0913 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04671509 0,09120329 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04671509 0,09110678 ! water homeostasis GO:0030104 8 8 0,000 0,04671509 0,09101047 ! cofactor transport GO:0051181 8 8 0,000 0,04671509 0,09091437 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04671509 0,09081846 ! acid secretion GO:0046717 8 8 0,000 0,04671509 0,09072276 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,04671509 0,09062727 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04671509 0,09053197 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04671509 0,09043687 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04671509 0,09034198 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04671509 0,09024728 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04671509 0,09015278 ! regulation of RNA stability GO:0043487 8 8 0,000 0,04671509 0,09005848 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,04671509 0,08996437 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04671509 0,08987046 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04671509 0,08977675 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04671509 0,08968323 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04671509 0,08958991 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04671509 0,08949678 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04671509 0,08940385 ! developmental induction GO:0031128 8 8 0,000 0,04671509 0,0893111 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04671509 0,08921855 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04671509 0,08912619 ! actin filament polymerization GO:0030041 9 8 0,000 0,04671509 0,08903403 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,04671509 0,08894205 ! peptide hormone processing GO:0016486 8 8 0,000 0,04671509 0,08885026 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04671509 0,08875866 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04671509 0,08866725 ! regulation of cell development GO:0060284 60 59 1,000 0,04788667 0,09079746 ! protein localization in organelle GO:0033365 59 59 1,000 0,04788667 0,09070414 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,04935474 0,09338891 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,05083917 0,09609906 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,05083917 0,0960006 ! axonogenesis GO:0007409 66 62 1,000 0,0523397 0,09873292 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,0523397 0,09863196 ! protein import GO:0017038 62 62 1,000 0,0523397 0,09853122 ! lactation GO:0007595 10 9 0,000 0,05240261 0,09854899 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05240261 0,09844854 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05240261 0,09834828 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05240261 0,09824823 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05240261 0,09814839 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05240261 0,09804875 ! viral genome replication GO:0019079 9 9 0,000 0,05240261 0,09794931 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05240261 0,09785007 ! copper ion transport GO:0006825 9 9 0,000 0,05240261 0,09775103 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05240261 0,09765219 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05240261 0,09755355 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05240261 0,09745511 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05240261 0,09735687 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05240261 0,09725883 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05240261 0,09716098 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05240261 0,09706333 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,05240261 0,09696588 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05240261 0,09686862 ! phospholipid efflux GO:0033700 9 9 0,000 0,05240261 0,09677156 ! response to alkaloid GO:0043279 10 9 0,000 0,05240261 0,09667469 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05240261 0,09657801 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05240261 0,09648153 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,05240261 0,09638524 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05240261 0,09628915 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05240261 0,09619324 ! response to ethanol GO:0045471 9 9 0,000 0,05240261 0,09609753 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,05240261 0,096002 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05240261 0,09590667 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,05240261 0,09581152 ! methionine metabolic process GO:0006555 9 9 0,000 0,05240261 0,09571657 ! glutamine metabolic process GO:0006541 9 9 0,000 0,05240261 0,0956218 ! response to osmotic stress GO:0006970 9 9 0,000 0,05240261 0,09552722 ! pigmentation during development GO:0048066 9 9 0,000 0,05240261 0,09543282 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05240261 0,09533861 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05240261 0,09524459 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05240261 0,09515075 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,05240261 0,0950571 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05240261 0,09496363 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05240261 0,09487035 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05240261 0,09477725 ! L-glutamate transport GO:0015813 9 9 0,000 0,05240261 0,09468433 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,05240261 0,09459159 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05240261 0,09449904 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05240261 0,09440666 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05240261 0,09431447 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05240261 0,09422245 ! DNA replication initiation GO:0006270 9 9 0,000 0,05240261 0,09413062 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05240261 0,09403896 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,05240261 0,09394749 ! regulation of cellular pH GO:0030641 9 9 0,000 0,05240261 0,09385619 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05240261 0,09376506 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05240261 0,09367412 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05240261 0,09358335 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05240261 0,09349275 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05240261 0,09340234 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,05240261 0,09331209 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05240261 0,09322202 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,05240261 0,09313213 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05240261 0,0930424 ! collagen catabolic process GO:0030574 9 9 0,000 0,05240261 0,09295285 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05240261 0,09286348 ! purine base metabolic process GO:0006144 9 9 0,000 0,05240261 0,09277427 ! gas transport GO:0015669 9 9 0,000 0,05240261 0,09268524 ! cholesterol efflux GO:0033344 9 9 0,000 0,05240261 0,09259637 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05240261 0,09250768 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05240261 0,09241915 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05240261 0,0923308 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05240261 0,09224261 ! defense response to virus GO:0051607 9 9 0,000 0,05240261 0,09215459 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05240261 0,09206674 ! actin filament-based movement GO:0030048 9 9 0,000 0,05240261 0,09197906 ! glucose metabolic process GO:0006006 63 63 1,000 0,0538561 0,09444034 ! angiogenesis GO:0001525 65 64 1,000 0,05538815 0,09703456 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,05538815 0,09694241 ! regulation of hormone levels GO:0010817 66 65 1,000 0,05693561 0,09955629 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,05805703 0,10142095 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,05805703 0,10132491 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,05805703 0,10122905 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,05805703 0,10113337 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,05805703 0,10103787 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,05805703 0,10094255 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,05805703 0,10084741 ! neuron maturation GO:0042551 10 10 0,000 0,05805703 0,10075245 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,05805703 0,10065767 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,05805703 0,10056307 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,05805703 0,10046864 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,05805703 0,10037439 ! hormone secretion GO:0046879 10 10 0,000 0,05805703 0,10028032 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,05805703 0,10018643 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,05805703 0,10009271 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,05805703 0,09999916 ! cAMP metabolic process GO:0046058 10 10 0,000 0,05805703 0,09990579 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,05805703 0,0998126 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,05805703 0,09971957 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,05805703 0,09962673 ! phototransduction GO:0007602 11 10 0,000 0,05805703 0,09953405 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,05805703 0,09944155 ! fat cell differentiation GO:0045444 10 10 0,000 0,05805703 0,09934921 ! myoblast differentiation GO:0045445 10 10 0,000 0,05805703 0,09925705 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,05805703 0,09916506 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,05805703 0,09907324 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,05805703 0,09898159 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,05805703 0,09889011 ! protein polyubiquitination GO:0000209 10 10 0,000 0,05805703 0,0987988 ! glutamate metabolic process GO:0006536 11 10 0,000 0,05805703 0,09870766 ! plasma membrane organization GO:0007009 10 10 0,000 0,05805703 0,09861669 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,05805703 0,09852588 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,05805703 0,09843524 ! lysosomal transport GO:0007041 10 10 0,000 0,05805703 0,09834476 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,05805703 0,09825446 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,05805703 0,09816432 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,05805703 0,09807434 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,05805703 0,09798453 ! exocrine system development GO:0035272 10 10 0,000 0,05805703 0,09789488 ! embryo implantation GO:0007566 11 10 0,000 0,05805703 0,0978054 ! regulation of protein binding GO:0043393 11 10 0,000 0,05805703 0,09771608 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,05805703 0,09762692 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,05805703 0,09753793 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,05805703 0,09744909 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,05805703 0,09736042 ! protein export from nucleus GO:0006611 10 10 0,000 0,05805703 0,09727191 ! negative regulation of immune response GO:0050777 10 10 0,000 0,05805703 0,09718356 ! cytolysis GO:0019835 10 10 0,000 0,05805703 0,09709538 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,05805703 0,09700735 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,05805703 0,09691948 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,05805703 0,09683177 ! histone deacetylation GO:0016575 10 10 0,000 0,05805703 0,09674422 ! mRNA splice site selection GO:0006376 11 10 0,000 0,05805703 0,09665682 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,05805703 0,09656959 ! gland morphogenesis GO:0022612 10 10 0,000 0,05805703 0,09648251 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,05805703 0,09639559 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,05805703 0,09630882 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,05805703 0,09622222 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,05805703 0,09613576 ! regulation of epidermis development GO:0045682 10 10 0,000 0,05805703 0,09604946 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,05805703 0,09596332 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,05805703 0,09587733 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,05805703 0,0957915 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,05805703 0,09570582 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,05805703 0,09562029 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,05805703 0,09553491 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,05805703 0,09544969 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,06007586 0,09868076 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! regulation of translation GO:0006417 69 69 1,000 0,06327506 0,10384322 ! sensory perception of sound GO:0007605 71 69 1,000 0,06327506 0,10375083 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 1,000 0,06327506 0,10365861 ! protein secretion GO:0009306 11 11 0,000 0,06367852 0,10422692 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06367852 0,10413444 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,06367852 0,10404212 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06367852 0,10394997 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06367852 0,10385798 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,06367852 0,10376615 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,06367852 0,10367448 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06367852 0,10358298 ! signal complex assembly GO:0007172 11 11 0,000 0,06367852 0,10349164 ! microtubule-based transport GO:0010970 11 11 0,000 0,06367852 0,10340046 ! endothelial cell migration GO:0043542 11 11 0,000 0,06367852 0,10330943 ! peroxisomal transport GO:0043574 11 11 0,000 0,06367852 0,10321857 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06367852 0,10312787 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,06367852 0,10303733 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,06367852 0,10294694 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,06367852 0,10285672 ! T cell proliferation GO:0042098 11 11 0,000 0,06367852 0,10276665 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,06367852 0,10267674 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! regulation of viral genome replication GO:0045069 11 11 0,000 0,06367852 0,10258699 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,06367852 0,10249739 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06367852 0,10240796 ! cellular response to starvation GO:0009267 11 11 0,000 0,06367852 0,10231867 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,06367852 0,10222954 ! digestive system process GO:0022600 11 11 0,000 0,06367852 0,10214057 ! fucose metabolic process GO:0006004 11 11 0,000 0,06367852 0,10205175 ! membrane budding GO:0006900 11 11 0,000 0,06367852 0,10196309 ! monoamine transport GO:0015844 11 11 0,000 0,06367852 0,10187458 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06367852 0,10178622 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,06367852 0,10169802 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,06367852 0,10160997 ! body fluid secretion GO:0007589 11 11 0,000 0,06367852 0,10152207 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,06367852 0,10143433 ! intermediate filament-based process GO:0045103 11 11 0,000 0,06367852 0,10134673 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06367852 0,10125929 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,06367852 0,101172 ! membrane depolarization GO:0051899 11 11 0,000 0,06367852 0,10108486 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,06367852 0,10099786 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06367852 0,10091102 ! oogenesis GO:0048477 11 11 0,000 0,06367852 0,10082433 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,06367852 0,10073778 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06367852 0,10065139 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,06367852 0,10056514 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,06367852 0,10047904 ! muscle maintenance GO:0046716 12 11 0,000 0,06367852 0,10039309 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,06367852 0,10030728 ! hindbrain development GO:0030902 11 11 0,000 0,06367852 0,10022162 ! steroid catabolic process GO:0006706 11 11 0,000 0,06367852 0,10013611 ! endocrine process GO:0050886 11 11 0,000 0,06367852 0,10005074 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,06367852 0,09996552 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,06367852 0,09988044 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06367852 0,09979551 ! cell part morphogenesis GO:0032990 75 70 1,000 0,06489621 0,10161743 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,06818052 0,10666952 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,06926728 0,10827786 ! translational initiation GO:0006413 12 12 0,000 0,06926728 0,1081861 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,06926728 0,10809449 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06926728 0,10800304 ! initiation of viral infection GO:0019059 12 12 0,000 0,06926728 0,10791175 ! iron ion transport GO:0006826 13 12 0,000 0,06926728 0,10782061 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06926728 0,10772962 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06926728 0,10763878 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06926728 0,1075481 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,06926728 0,10745757 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06926728 0,1073672 ! collagen metabolic process GO:0032963 12 12 0,000 0,06926728 0,10727697 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06926728 0,1071869 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06926728 0,10709698 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06926728 0,10700721 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06926728 0,10691759 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06926728 0,10682812 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06926728 0,10673879 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,06926728 0,10664962 ! actomyosin structure organization GO:0031032 12 12 0,000 0,06926728 0,1065606 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,06926728 0,10647172 ! retinoid metabolic process GO:0001523 12 12 0,000 0,06926728 0,106383 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06926728 0,10629442 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06926728 0,10620599 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06926728 0,1061177 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06926728 0,10602957 ! acute-phase response GO:0006953 12 12 0,000 0,06926728 0,10594158 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06926728 0,10585373 ! vacuolar transport GO:0007034 12 12 0,000 0,06926728 0,10576603 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06926728 0,10567848 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06926728 0,10559107 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06926728 0,1055038 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06926728 0,10541668 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,06926728 0,1053297 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,06926728 0,10524287 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06926728 0,10515618 ! renal system process GO:0003014 12 12 0,000 0,06926728 0,10506963 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06926728 0,10498322 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06926728 0,10489696 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,06926728 0,10481084 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06926728 0,10472485 ! cell fate determination GO:0001709 12 12 0,000 0,06926728 0,10463901 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,06926728 0,10455332 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06926728 0,10446776 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06926728 0,10438234 ! detection of light stimulus GO:0009583 13 12 0,000 0,06926728 0,10429706 ! synaptogenesis GO:0007416 12 12 0,000 0,06926728 0,10421192 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06926728 0,10412692 ! hormone transport GO:0009914 12 12 0,000 0,06926728 0,10404205 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06926728 0,10395733 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06926728 0,10387274 ! spermatid differentiation GO:0048515 13 12 0,000 0,06926728 0,10378829 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06926728 0,10370398 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06926728 0,1036198 ! neural tube closure GO:0001843 13 12 0,000 0,06926728 0,10353576 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,06926728 0,10345186 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,06926728 0,1033681 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,07482349 0,11156933 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,07482349 0,11147914 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,07482349 0,11138909 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,07482349 0,11129919 ! phenol metabolic process GO:0018958 13 13 0,000 0,07482349 0,11120943 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,07482349 0,11111982 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,07482349 0,11103035 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,07482349 0,11094102 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,07482349 0,11085184 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,07482349 0,1107628 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,07482349 0,11067391 ! regeneration GO:0031099 13 13 0,000 0,07482349 0,11058516 ! keratinization GO:0031424 13 13 0,000 0,07482349 0,11049655 ! post-embryonic development GO:0009791 14 13 0,000 0,07482349 0,11040808 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,07482349 0,11031975 ! patterning of blood vessels GO:0001569 13 13 0,000 0,07482349 0,11023157 ! vasculogenesis GO:0001570 13 13 0,000 0,07482349 0,11014352 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,07482349 0,11005562 ! regulation of innate immune response GO:0045088 13 13 0,000 0,07482349 0,10996786 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,07482349 0,10988023 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,07482349 0,10979275 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,07482349 0,1097054 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,07482349 0,1096182 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,07482349 0,10953113 ! autophagy GO:0006914 13 13 0,000 0,07482349 0,1094442 ! receptor metabolic process GO:0043112 14 13 0,000 0,07482349 0,10935741 ! actin filament bundle formation GO:0051017 13 13 0,000 0,07482349 0,10927075 ! cell aging GO:0007569 13 13 0,000 0,07482349 0,10918424 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,07482349 0,10909786 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,07482349 0,10901161 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,07482349 0,10892551 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,07482349 0,10883954 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,07482349 0,1087537 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,07482349 0,108668 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,07482349 0,10858243 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,07482349 0,108497 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,07482349 0,10841171 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,07482349 0,10832654 ! vasodilation GO:0042311 14 13 0,000 0,07482349 0,10824152 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,07482349 0,10815662 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,07482349 0,10807186 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,07482349 0,10798723 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,07482349 0,10790273 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,07482349 0,10781837 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,07482349 0,10773413 ! immunoglobulin production GO:0002377 13 13 0,000 0,07482349 0,10765003 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,07482349 0,10756606 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,07482349 0,10748222 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,07482349 0,10739851 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,07482349 0,10731493 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,07482349 0,10723149 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,07482349 0,10714817 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,07482349 0,10706498 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,07482349 0,10698192 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,07482349 0,10689899 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,07482349 0,10681618 ! telomere organization GO:0032200 13 13 0,000 0,07482349 0,10673351 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,07482349 0,10665096 ! regulation of amine transport GO:0051952 13 13 0,000 0,07482349 0,10656854 ! tissue homeostasis GO:0001894 13 13 0,000 0,07482349 0,10648625 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,07482349 0,10640408 ! protein tetramerization GO:0051262 13 13 0,000 0,07482349 0,10632204 ! regulation of protein modification process GO:0031399 79 78 1,000 0,07835426 0,1112534 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,07835426 0,11116775 ! nuclear transport GO:0051169 79 79 1,000 0,08009449 0,11354935 GO:0006913|nucleocytoplasmic transport, ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,08034733 0,11382024 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,08034733 0,11373282 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,08034733 0,11364554 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,08034733 0,11355839 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,08034733 0,11347137 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,08034733 0,11338448 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,08034733 0,11329773 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,08034733 0,11321111 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,08034733 0,11312463 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,08034733 0,11303827 ! vesicle docking GO:0048278 14 14 0,000 0,08034733 0,11295205 ! superoxide metabolic process GO:0006801 15 14 0,000 0,08034733 0,11286596 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,08034733 0,11278 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,08034733 0,11269417 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,08034733 0,11260847 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,08034733 0,1125229 ! hair cycle GO:0042633 14 14 0,000 0,08034733 0,11243746 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,08034733 0,11235215 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,08034733 0,11226697 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,08034733 0,11218192 ! lysosome organization GO:0007040 14 14 0,000 0,08034733 0,112097 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,08034733 0,11201221 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,08034733 0,11192754 ! peptide transport GO:0015833 14 14 0,000 0,08034733 0,111843 ! primary neural tube formation GO:0014020 15 14 0,000 0,08034733 0,11175859 ! peptide cross-linking GO:0018149 14 14 0,000 0,08034733 0,11167431 ! regulation of behavior GO:0050795 14 14 0,000 0,08034733 0,11159015 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,08034733 0,11150613 ! base-excision repair GO:0006284 14 14 0,000 0,08034733 0,11142222 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,08034733 0,11133845 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,08034733 0,1112548 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,08034733 0,11117127 ! formation of primary germ layer GO:0001704 14 14 0,000 0,08034733 0,11108787 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,08034733 0,1110046 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,08034733 0,11092145 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,08034733 0,11083842 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,08034733 0,11075552 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,08034733 0,11067275 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,08034733 0,11059009 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,08034733 0,11050756 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,08034733 0,11042516 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,08034733 0,11034287 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,08034733 0,11026071 ! neuron projection development GO:0031175 85 80 1,000 0,08184693 0,11223503 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,085839 0,11762176 ! positive regulation of ossification GO:0045778 15 15 0,000 0,085839 0,11753438 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,085839 0,11744712 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,085839 0,11735999 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,085839 0,117273 ! response to vitamin GO:0033273 15 15 0,000 0,085839 0,11718613 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,085839 0,11709939 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,085839 0,11701277 ! ovarian follicle development GO:0001541 15 15 0,000 0,085839 0,11692629 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,085839 0,11683993 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,085839 0,11675371 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,085839 0,1166676 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,085839 0,11658163 ! heme metabolic process GO:0042168 15 15 0,000 0,085839 0,11649578 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,085839 0,11641006 ! chromosome condensation GO:0030261 15 15 0,000 0,085839 0,11632446 ! response to starvation GO:0042594 15 15 0,000 0,085839 0,11623899 ! response to ionizing radiation GO:0010212 16 15 0,000 0,085839 0,11615365 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,085839 0,11606843 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,085839 0,11598334 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,085839 0,11589837 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,085839 0,11581352 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,085839 0,1157288 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,085839 0,1156442 ! phospholipid transport GO:0015914 15 15 0,000 0,085839 0,11555973 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,085839 0,11547538 ! glutathione metabolic process GO:0006749 16 15 0,000 0,085839 0,11539115 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,085839 0,11530705 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,085839 0,11522307 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,085839 0,11513921 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,085839 0,11505547 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,085839 0,11497185 ! protein homooligomerization GO:0051260 15 15 0,000 0,085839 0,11488836 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,085839 0,11480499 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,09078525 0,12133228 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,09129866 0,12193002 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,09129866 0,12184173 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,09129866 0,12175357 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,09129866 0,12166553 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,09129866 0,12157763 ! circadian rhythm GO:0007623 16 16 0,000 0,09129866 0,12148984 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,09129866 0,12140219 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,09129866 0,12131466 ! vacuole organization GO:0007033 16 16 0,000 0,09129866 0,12122726 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,09129866 0,12113998 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,09129866 0,12105283 ! vesicle targeting GO:0006903 17 16 0,000 0,09129866 0,1209658 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,09129866 0,1208789 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,09129866 0,12079213 ! iron ion homeostasis GO:0055072 16 16 0,000 0,09129866 0,12070548 ! positive regulation of cell development GO:0010720 16 16 0,000 0,09129866 0,12061895 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,09129866 0,12053255 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,09129866 0,12044627 ! pentose metabolic process GO:0019321 16 16 0,000 0,09129866 0,12036011 ! fatty acid transport GO:0015908 16 16 0,000 0,09129866 0,12027408 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,09129866 0,12018817 ! cofactor catabolic process GO:0051187 16 16 0,000 0,09129866 0,12010238 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,09129866 0,12001671 ! polyol metabolic process GO:0019751 16 16 0,000 0,09129866 0,11993117 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,09129866 0,11984575 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,09129866 0,11976045 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,09129866 0,11967527 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,09129866 0,11959022 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,09129866 0,11950528 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,09129866 0,11942046 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,09129866 0,11933577 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,09129866 0,11925119 ! regulation of coagulation GO:0050818 17 16 0,000 0,09129866 0,11916674 ! hexose metabolic process GO:0019318 87 86 1,000 0,0926068 0,12078862 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,09672651 0,12607281 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,09672651 0,12598372 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,09672651 0,12589475 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,09672651 0,1258059 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,09672651 0,12571718 ! leukocyte adhesion GO:0007159 17 17 0,000 0,09672651 0,12562858 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,09672651 0,12554011 ! sensory perception of smell GO:0007608 17 17 0,000 0,09672651 0,12545177 ! glucose transport GO:0015758 17 17 0,000 0,09672651 0,12536354 ! cell junction assembly GO:0034329 18 17 0,000 0,09672651 0,12527545 ! tissue remodeling GO:0048771 17 17 0,000 0,09672651 0,12518747 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,09672651 0,12509962 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,09672651 0,12501189 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,09672651 0,12492429 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,09672651 0,12483681 ! neural crest cell development GO:0014032 19 17 0,000 0,09672651 0,12474945 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,09672651 0,12466221 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,09672651 0,12457509 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,09672651 0,1244881 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,09672651 0,12440123 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,09672651 0,12431448 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,09672651 0,12422785 ! adult locomotory behavior GO:0008344 17 17 0,000 0,09672651 0,12414134 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,09672651 0,12405495 ! gene silencing GO:0016458 17 17 0,000 0,09672651 0,12396868 ! chemotaxis GO:0006935 90 89 1,000 0,09813579 0,12568747 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,09999963 0,12798563 ! DNA replication GO:0006260 91 91 1,000 0,10187358 0,13029355 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,10212272 0,13052162 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,10212272 0,13043117 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,10212272 0,13034085 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,10212272 0,13025064 ! membrane docking GO:0022406 18 18 0,000 0,10212272 0,13016057 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,10212272 0,13007062 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,10212272 0,12998079 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,10212272 0,12989108 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,10212272 0,1298015 ! hexose transport GO:0008645 18 18 0,000 0,10212272 0,12971205 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,10212272 0,12962271 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,10212272 0,1295335 ! striated muscle contraction GO:0006941 18 18 0,000 0,10212272 0,12944442 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,10212272 0,12935545 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,10212272 0,12926661 ! ceramide metabolic process GO:0006672 18 18 0,000 0,10212272 0,12917789 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,10212272 0,12908929 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,10212272 0,12900081 ! B cell differentiation GO:0030183 18 18 0,000 0,10212272 0,12891245 ! BMP signaling pathway GO:0030509 18 18 0,000 0,10212272 0,12882422 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,10212272 0,1287361 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,10212272 0,12864811 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,10748748 0,13531382 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,10748748 0,13522145 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,10748748 0,13512921 ! regulation of pH GO:0006885 19 19 0,000 0,10748748 0,1350371 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,10748748 0,13494512 ! feeding behavior GO:0007631 19 19 0,000 0,10748748 0,13485325 ! peroxisome organization GO:0007031 19 19 0,000 0,10748748 0,13476152 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,10748748 0,1346699 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,10748748 0,13457842 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,10748748 0,13448705 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,10748748 0,13439581 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,10748748 0,1343047 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,10748748 0,13421371 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,10748748 0,13412284 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,10748748 0,13403209 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,10748748 0,13394147 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,10748748 0,13385097 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,10748748 0,13376059 ! regulation of cell shape GO:0008360 21 19 0,000 0,10748748 0,13367033 ! placenta development GO:0001890 19 19 0,000 0,10748748 0,13358019 ! vesicle localization GO:0051648 20 19 0,000 0,10748748 0,13349018 ! regulation of muscle development GO:0048634 21 20 0,000 0,11282096 0,14001955 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,11282096 0,13992533 ! negative regulation of binding GO:0051100 21 20 0,000 0,11282096 0,13983123 ! organic ether metabolic process GO:0018904 20 20 0,000 0,11282096 0,13973725 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,11282096 0,13964341 ! phagocytosis GO:0006909 21 20 0,000 0,11282096 0,13954969 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,11282096 0,13945609 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,11282096 0,13936262 ! protein targeting to membrane GO:0006612 22 20 0,000 0,11282096 0,13926928 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,11282096 0,13917606 ! chromatin remodeling GO:0006338 20 20 0,000 0,11282096 0,13908297 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,11282096 0,13899 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,11282096 0,13889715 ! lipid oxidation GO:0034440 20 20 0,000 0,11282096 0,13880443 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,11282096 0,13871183 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,11282096 0,13861936 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,11282096 0,13852701 ! RNA modification GO:0009451 20 20 0,000 0,11282096 0,13843478 ! single fertilization GO:0007338 21 20 0,000 0,11282096 0,13834267 ! blood circulation GO:0008015 99 98 1,000 0,11525966 0,14123906 GO:0003013|circulatory system process, ! mRNA catabolic process GO:0006402 21 21 0,000 0,11812334 0,14465204 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,11812334 0,14455599 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,11812334 0,14446007 ! Notch signaling pathway GO:0007219 22 21 0,000 0,11812334 0,14436427 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,11812334 0,1442686 ! ear morphogenesis GO:0042471 21 21 0,000 0,11812334 0,14417306 ! organic anion transport GO:0015711 21 21 0,000 0,11812334 0,14407765 ! cholesterol transport GO:0030301 21 21 0,000 0,11812334 0,14398236 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,11812334 0,14388719 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,11812334 0,14379216 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,11812334 0,14369724 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,11812334 0,14360246 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,11812334 0,14350779 ! regulation of proteolysis GO:0030162 21 21 0,000 0,11812334 0,14341326 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,11812334 0,14331884 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,11812334 0,14322456 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,11812334 0,14313039 ! RNA export from nucleus GO:0006405 22 22 0,000 0,1233948 0,1494196 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,1233948 0,14932149 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,1233948 0,14922351 ! regulation of ion transport GO:0043269 22 22 0,000 0,1233948 0,14912566 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,1233948 0,14902793 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,1233948 0,14893034 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,1233948 0,14883287 ! ovulation cycle process GO:0022602 22 22 0,000 0,1233948 0,14873553 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,1233948 0,14863832 ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,1233948 0,14854123 ! male sex differentiation GO:0046661 22 22 0,000 0,1233948 0,14844427 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,1233948 0,14834744 ! biopolymer methylation GO:0043414 22 22 0,000 0,1233948 0,14825073 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,1233948 0,14815415 ! detection of external stimulus GO:0009581 23 22 0,000 0,1233948 0,1480577 ! neuron migration GO:0001764 22 22 0,000 0,1233948 0,14796137 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,1233948 0,14786517 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,1233948 0,14776909 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,1233948 0,14767313 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,1233948 0,1475773 ! aerobic respiration GO:0009060 22 22 0,000 0,1233948 0,1474816 ! cytokine production GO:0001816 22 22 0,000 0,1233948 0,14738602 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,1233948 0,14729056 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,12863552 0,15344677 ! viral infectious cycle GO:0019058 23 23 0,000 0,12863552 0,15334752 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,12863552 0,15324839 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,12863552 0,15314939 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,12863552 0,15305052 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,12863552 0,15295178 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,12863552 0,15285317 ! positive regulation of growth GO:0045927 23 23 0,000 0,12863552 0,15275468 ! female gonad development GO:0008585 23 23 0,000 0,12863552 0,15265632 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,12863552 0,15255808 ! lipid homeostasis GO:0055088 23 23 0,000 0,12863552 0,15245997 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,12863552 0,15236199 ! mitochondrial transport GO:0006839 24 24 0,000 0,13384566 0,15843131 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,13384566 0,15832962 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,13384566 0,15822806 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,13384566 0,15812664 ! T cell differentiation GO:0030217 24 24 0,000 0,13384566 0,15802534 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,13384566 0,15792417 ! ovulation cycle GO:0042698 24 24 0,000 0,13384566 0,15782313 ! fertilization GO:0009566 25 24 0,000 0,13384566 0,15772222 ! maintenance of protein location GO:0045185 25 24 0,000 0,13384566 0,15762144 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,13384566 0,15752079 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,1390254 0,16351233 ! negative regulation of secretion GO:0051048 26 25 0,000 0,1390254 0,16340805 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,1390254 0,1633039 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,1390254 0,16319989 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,1390254 0,163096 ! endosome transport GO:0016197 25 25 0,000 0,1390254 0,16299225 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,1390254 0,16288863 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,1390254 0,16278515 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,1390254 0,16268179 ! excretion GO:0007588 25 25 0,000 0,1390254 0,16257857 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,1390254 0,16247547 ! gastrulation GO:0007369 25 25 0,000 0,1390254 0,16237251 ! heart morphogenesis GO:0003007 25 25 0,000 0,1390254 0,16226968 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,1390254 0,16216698 ! regulation of endocytosis GO:0030100 25 25 0,000 0,1390254 0,1620644 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,1390254 0,16196196 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,1390254 0,16185965 ! positive regulation of defense response GO:0031349 26 26 0,000 0,14417492 0,16774898 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,14417492 0,16764315 ! cellular defense response GO:0006968 26 26 0,000 0,14417492 0,16753744 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,14417492 0,16743188 ! double-strand break repair GO:0006302 27 26 0,000 0,14417492 0,16732644 ! regulation of protein secretion GO:0050708 26 26 0,000 0,14417492 0,16722114 ! germ cell development GO:0007281 27 26 0,000 0,14417492 0,16711597 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,14417492 0,16701093 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,14417492 0,16690602 ! response to insulin stimulus GO:0032868 28 26 0,000 0,14417492 0,16680125 ! maintenance of location in cell GO:0051651 27 26 0,000 0,14417492 0,1666966 ! chloride transport GO:0006821 27 27 0,000 0,14929439 0,17250756 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,14929439 0,17239948 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,14929439 0,17229152 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,14929439 0,17218371 ! peptide metabolic process GO:0006518 29 27 0,000 0,14929439 0,17207602 ! activation of caspase activity GO:0006919 27 27 0,000 0,14929439 0,17196848 ! inner ear development GO:0048839 27 27 0,000 0,14929439 0,17186106 ! defense response to bacterium GO:0042742 27 27 0,000 0,14929439 0,17175379 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,14929439 0,17164664 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,14929439 0,17153963 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,15438398 0,17727705 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,15438398 0,17716667 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,15438398 0,17705642 ! carbohydrate transport GO:0008643 28 28 0,000 0,15438398 0,17694631 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,15438398 0,17683634 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,15438398 0,1767265 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,15438398 0,1766168 ! cartilage development GO:0051216 29 28 0,000 0,15438398 0,17650724 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,15944385 0,18217918 ! viral reproductive process GO:0022415 29 29 0,000 0,15944385 0,18206631 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,15944385 0,18195357 ! antigen processing and presentation GO:0019882 29 29 0,000 0,15944385 0,18184098 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,15944385 0,18172852 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,15944385 0,1816162 ! adult behavior GO:0030534 30 29 0,000 0,15944385 0,18150403 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,15944385 0,18139199 ! transition metal ion transport GO:0000041 31 30 0,000 0,16447418 0,18699933 ! RNA catabolic process GO:0006401 30 30 0,000 0,16447418 0,18688404 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,16447418 0,1867689 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,16447418 0,18665389 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,16447418 0,18653903 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,16447418 0,1864243 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,16447418 0,18630972 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,16447418 0,18619528 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,16447418 0,18608098 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,16447418 0,18596682 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,16447418 0,1858528 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,16447418 0,18573892 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,16447418 0,18562518 ! vesicle organization GO:0016050 30 30 0,000 0,16447418 0,18551158 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,16447418 0,18539812 ! membrane fusion GO:0006944 31 31 0,000 0,16947514 0,19091851 ! B cell activation GO:0042113 31 31 0,000 0,16947514 0,19080188 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,16947514 0,1906854 ! ion transmembrane transport GO:0034220 31 31 0,000 0,16947514 0,19056906 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,16947514 0,19045286 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,16947514 0,1903368 ! digestion GO:0007586 31 31 0,000 0,16947514 0,19022088 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,16947514 0,1901051 ! regulation of heart contraction GO:0008016 31 31 0,000 0,16947514 0,18998947 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,16947514 0,18987397 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,16947514 0,18975862 ! cell redox homeostasis GO:0045454 32 32 0,000 0,17444689 0,19520681 ! lipid modification GO:0030258 32 32 0,000 0,17444689 0,19508836 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,17444689 0,19497005 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,17444689 0,19485189 ! nuclear export GO:0051168 32 32 0,000 0,17444689 0,19473387 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,17444689 0,19461599 ! maintenance of location GO:0051235 33 32 0,000 0,17444689 0,19449826 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,1793896 0,19988817 ! amino acid transport GO:0006865 33 33 0,000 0,1793896 0,19976739 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,1793896 0,19964676 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,1793896 0,19952627 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,1793896 0,19940593 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,1793896 0,19928573 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,1793896 0,19916568 ! regulation of actin filament length GO:0030832 34 34 0,000 0,18430344 0,20449803 ! response to metal ion GO:0010038 34 34 0,000 0,18430344 0,20437499 ! ear development GO:0043583 34 34 0,000 0,18430344 0,20425209 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,18430344 0,20412935 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,18430344 0,20400675 ! secondary metabolic process GO:0019748 34 34 0,000 0,18430344 0,20388429 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,18430344 0,20376199 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,18430344 0,20363983 ! detection of stimulus GO:0051606 36 34 0,000 0,18430344 0,20351781 ! acute inflammatory response GO:0002526 35 35 0,000 0,18918856 0,20878713 ! regulation of cellular component size GO:0032535 35 35 0,000 0,18918856 0,20866219 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,18918856 0,20853739 ! mesoderm development GO:0007498 35 35 0,000 0,18918856 0,20841274 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,18918856 0,20828824 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,18918856 0,20816389 ! inorganic anion transport GO:0015698 35 35 0,000 0,18918856 0,20803969 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,18918856 0,20791563 ! regulation of immune effector process GO:0002697 35 35 0,000 0,18918856 0,20779173 ! hydrogen transport GO:0006818 36 36 0,000 0,19404514 0,21299892 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,19404514 0,21287213 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,19404514 0,2127455 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,19404514 0,21261902 ! female pregnancy GO:0007565 37 36 0,000 0,19404514 0,21249268 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,19404514 0,2123665 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,19404514 0,21224047 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,19404514 0,21211458 ! gonad development GO:0008406 36 36 0,000 0,19404514 0,21198885 ! activation of immune response GO:0002253 36 36 0,000 0,19404514 0,21186326 ! coagulation GO:0050817 39 36 0,000 0,19404514 0,21173783 GO:0007596|blood coagulation, ! response to drug GO:0042493 37 37 0,000 0,19887333 0,21687784 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,19887333 0,21674958 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,19887333 0,21662148 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,19887333 0,21649353 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,19887333 0,21636573 ! adaptive immune response GO:0002250 37 37 0,000 0,19887333 0,21623808 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,2036733 0,22132659 ! neurotransmitter transport GO:0006836 40 38 0,000 0,2036733 0,22119616 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,2036733 0,22106589 ! exocytosis GO:0006887 40 38 0,000 0,2036733 0,22093578 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,2036733 0,22080582 ! regulation of neurological system process GO:0031644 38 38 0,000 0,2036733 0,22067601 ! hemostasis GO:0007599 42 39 0,000 0,20844521 0,22571358 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,20844521 0,22558104 ! activation of MAPK activity GO:0000187 39 39 0,000 0,20844521 0,22544866 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,20844521 0,22531643 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,20844521 0,22518436 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,20844521 0,22505244 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,20844521 0,22492068 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,20844521 0,22478907 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,20844521 0,22465761 ! protein oligomerization GO:0051259 39 39 0,000 0,20844521 0,22452631 ! amine catabolic process GO:0009310 42 41 0,000 0,21790548 0,23457932 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,21790548 0,23444238 ! regulation of caspase activity GO:0043281 41 41 0,000 0,21790548 0,2343056 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,21790548 0,23416898 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,21790548 0,23403251 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,22259416 0,23892896 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,22259416 0,23878989 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,22259416 0,23865098 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,22259416 0,23851223 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,22259416 0,23837364 ! protein ubiquitination GO:0016567 43 42 0,000 0,22259416 0,23823521 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,22259416 0,23809694 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! one-carbon metabolic process GO:0006730 42 42 0,000 0,22259416 0,23795883 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,22725541 0,24280099 ! humoral immune response GO:0006959 44 44 0,000 0,23188939 0,24760843 ! mRNA transport GO:0051028 44 44 0,000 0,23188939 0,24746505 ! vitamin metabolic process GO:0006766 44 44 0,000 0,23188939 0,24732184 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,23188939 0,2471788 ! amine biosynthetic process GO:0009309 46 45 0,000 0,23649625 0,2519437 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,23649625 0,25179815 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,23649625 0,25165277 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,23649625 0,25150756 ! protein processing GO:0016485 45 45 0,000 0,23649625 0,25136251 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,24107616 0,25608263 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,24107616 0,25593512 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,24107616 0,25578777 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,24107616 0,2556406 ! amine transport GO:0015837 47 47 0,000 0,24562926 0,26031899 ! rhythmic process GO:0048511 47 47 0,000 0,24562926 0,26016938 ! calcium ion transport GO:0006816 48 48 0,000 0,2501557 0,26481158 ! actin filament organization GO:0007015 50 48 0,000 0,2501557 0,26465956 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,2501557 0,26450772 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,25465565 0,26911144 ! divalent metal ion transport GO:0070838 49 49 0,000 0,25465565 0,26895723 ! response to bacterium GO:0009617 50 49 0,000 0,25465565 0,26880318 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,25465565 0,26864932 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,25465565 0,26849563 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,25912924 0,27305614 ! chromatin assembly GO:0031497 50 50 0,000 0,25912924 0,27290011 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,25912924 0,27274426 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,25912924 0,27258858 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,25912924 0,27243308 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,26357664 0,27695082 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,26357664 0,27679301 ! positive regulation of immune response GO:0050778 51 51 0,000 0,26357664 0,27663539 ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,26357664 0,27647794 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,26357664 0,27632067 ! protein maturation GO:0051604 51 51 0,000 0,26357664 0,27616358 ! RNA localization GO:0006403 52 52 0,000 0,26799798 0,28063652 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,26799798 0,28047716 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,26799798 0,28031798 ! sodium ion transport GO:0006814 53 53 0,000 0,27239342 0,28475387 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,27239342 0,28459245 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,27239342 0,2844312 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,27676311 0,28883036 ! response to virus GO:0009615 54 54 0,000 0,27676311 0,2886669 ! sulfur metabolic process GO:0006790 55 54 0,000 0,27676311 0,28850363 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,27676311 0,28834054 ! nucleosome organization GO:0034728 55 55 0,000 0,28110719 0,29270088 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,28110719 0,29253561 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,28110719 0,29237052 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,28542582 0,29669474 ! ATP metabolic process GO:0046034 57 57 0,000 0,28971913 0,3009878 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,28971913 0,30081823 ! innate immune response GO:0045087 58 58 0,000 0,29398727 0,305078 ! dephosphorylation GO:0016311 60 59 0,000 0,29823038 0,30930703 ! carboxylic acid transport GO:0046942 59 59 0,000 0,29823038 0,30913307 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,29823038 0,3089593 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,29823038 0,30878573 ! immune effector process GO:0002252 59 59 0,000 0,29823038 0,30861235 ! potassium ion transport GO:0006813 60 60 0,000 0,30244861 0,31280179 ! protein polymerization GO:0051258 65 60 0,000 0,30244861 0,31262636 ! cellular respiration GO:0045333 62 61 0,000 0,3066421 0,31678329 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,3066421 0,31660582 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,3066421 0,31642855 ! lipid transport GO:0006869 62 62 0,000 0,31081099 0,32055101 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,31081099 0,32037174 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,31081099 0,32019266 ! regulation of secretion GO:0051046 65 63 0,000 0,31495543 0,32428092 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,31495543 0,32409986 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,31495543 0,323919 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,31907554 0,32797336 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,31907554 0,32779054 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,31907554 0,32760793 ! anion transport GO:0006820 65 65 0,000 0,32317148 0,33162864 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,32724338 0,33562022 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,32724338 0,33543356 ! DNA packaging GO:0006323 66 66 0,000 0,32724338 0,3352471 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,33129137 0,33920555 ! muscle contraction GO:0006936 67 67 0,000 0,33129137 0,33901721 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,33531559 0,34294486 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,33531559 0,34275465 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,34329329 0,35071482 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,34724703 0,3545575 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,34724703 0,35436117 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,34724703 0,35416507 GO:0006874|cellular calcium ion homeostasis, ! secretion by cell GO:0032940 75 72 0,000 0,35117755 0,35797578 ! muscle system process GO:0003012 72 72 0,000 0,35117755 0,3577779 ! regulation of cytokine production GO:0001817 72 72 0,000 0,35117755 0,35758023 ! electron transport chain GO:0022900 75 74 0,000 0,35896943 0,36531234 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,35896943 0,36511074 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,36283106 0,36883488 ! response to oxidative stress GO:0006979 76 75 0,000 0,36283106 0,36863155 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,36283106 0,36842845 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,36666999 0,37212158 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,37048635 0,37578775 ! microtubule-based movement GO:0007018 82 78 0,000 0,37428027 0,37942714 ! metal ion homeostasis GO:0055065 78 78 0,000 0,37428027 0,37921855 ! regulation of immune response GO:0050776 78 78 0,000 0,37428027 0,37901019 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,38180132 0,38641396 ! MAPKKK cascade GO:0000165 82 81 0,000 0,38552869 0,38997222 ! lymphocyte activation GO:0046649 82 81 0,000 0,38552869 0,3897583 ! lipid catabolic process GO:0016042 82 81 0,000 0,38552869 0,38954461 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,39291778 0,39679313 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,39657974 0,40027189 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,40022015 0,40372509 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,40022015 0,40350424 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,40383913 0,4069303 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,4110133 0,41393306 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,4110133 0,41370699 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,41456872 0,41705795 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,42161687 0,42391702 ! visual perception GO:0007601 93 92 0,000 0,42510983 0,42719597 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,42510983 0,42696317 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,42510983 0,42673062 ! regulation of response to stress GO:0080134 97 94 0,000 0,43203412 0,43344523 ! cofactor metabolic process GO:0051186 95 94 0,000 0,43203412 0,4332094 ! endocytosis GO:0006897 99 98 0,000 0,44563946 0,44660877 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,44563946 0,44636605 ! regulation of system process GO:0044057 98 98 0,000 0,44563946 0,44612359 ! response to hormone stimulus GO:0009725 102 100 0,000 0,45232237 0,45256793 ! response to other organism GO:0051707 101 100 0,000 0,45232237 0,45232237