pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6634-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! actin cytoskeleton reorganization GO:0031532 5 5 2,000 2,255E-06 4,156E-03 ! cellular response to insulin stimulus GO:0032869 23 21 3,000 7,33E-06 6,754E-03 ! regulation of gene-specific transcription GO:0032583 25 25 3,000 1,521E-05 9,346E-03 ! response to insulin stimulus GO:0032868 28 26 3,000 1,79E-05 8,247E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 2,429E-05 8,954E-03 ! microtubule-based transport GO:0010970 11 11 2,000 3,624E-05 0,01113278 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 3,624E-05 9,542E-03 GO:0032388|positive regulation of intracellular transport, ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 3,624E-05 8,35E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 2,000 3,624E-05 7,422E-03 ! regulation of DNA replication GO:0006275 32 31 3,000 3,682E-05 6,787E-03 ! response to peptide hormone stimulus GO:0043434 36 34 3,000 5,354E-05 8,971E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 6,228E-05 9,565E-03 ! negative regulation of DNA replication GO:0008156 13 13 2,000 6,228E-05 8,829E-03 ! receptor metabolic process GO:0043112 14 13 2,000 6,228E-05 8,198E-03 ! negative regulation of protein catabolic process GO:0042177 13 13 2,000 6,228E-05 7,652E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 2,000 6,228E-05 7,173E-03 ! protein tetramerization GO:0051262 13 13 2,000 6,228E-05 6,751E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 6,739E-05 6,9E-03 ! meiosis GO:0007126 37 37 3,000 7,522E-05 7,296E-03 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 7,892E-05 7,272E-03 ! chromosome segregation GO:0007059 38 38 3,000 8,369E-05 7,345E-03 ! meiotic cell cycle GO:0051321 38 38 3,000 8,369E-05 7,011E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 9,283E-05 7,438E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 9,821E-05 7,542E-03 ! fatty acid transport GO:0015908 16 16 2,000 1,204E-04 8,872E-03 ! cell-substrate adhesion GO:0031589 43 42 3,000 1,246E-04 8,833E-03 ! glucose transport GO:0015758 17 17 2,000 1,455E-04 9,932E-03 ! response to toxin GO:0009636 18 17 2,000 1,455E-04 9,577E-03 ! hexose transport GO:0008645 18 18 2,000 1,738E-04 0,01104837 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 18 18 2,000 1,738E-04 0,01068009 ! ensheathment of neurons GO:0007272 18 18 2,000 1,738E-04 0,01033557 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 2,000 1,738E-04 0,01001259 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 1,784E-04 9,964E-03 ! regulation of membrane potential GO:0042391 46 46 3,000 1,784E-04 9,671E-03 ! heart development GO:0007507 90 87 4,000 1,899E-04 0,01000134 ! regulation of catabolic process GO:0009894 48 47 3,000 1,941E-04 9,938E-03 ! negative regulation of DNA metabolic process GO:0051053 19 19 2,000 2,055E-04 0,01023846 ! placenta development GO:0001890 19 19 2,000 2,055E-04 9,969E-03 ! leukocyte differentiation GO:0002521 50 49 3,000 2,285E-04 0,01079921 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 2,285E-04 0,01052923 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 2,000 2,408E-04 0,01082282 ! positive regulation of gene-specific transcription GO:0043193 20 20 2,000 2,408E-04 0,01056513 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 2,473E-04 0,0105982 ! DNA integrity checkpoint GO:0031570 21 21 2,000 2,797E-04 0,01171454 ! regulation of action potential in neuron GO:0019228 21 21 2,000 2,797E-04 0,01145422 ! response to light stimulus GO:0009416 53 52 3,000 2,881E-04 0,01154093 ! spindle organization GO:0007051 22 22 2,000 3,224E-04 0,01264319 ! microtubule cytoskeleton organization GO:0000226 55 55 3,000 3,58E-04 0,01374517 ! response to hormone stimulus GO:0009725 102 100 4,000 3,645E-04 0,01370918 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 3,771E-04 0,01389867 ! prostate gland development GO:0030850 5 5 1,000 3,771E-04 0,01362615 ! mRNA stabilization GO:0048255 5 5 1,000 3,771E-04 0,01336411 GO:0043489|RNA stabilization, ! memory GO:0007613 5 5 1,000 3,771E-04 0,01311196 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 3,771E-04 0,01286914 ! response to lipid GO:0033993 5 5 1,000 3,771E-04 0,01263516 ! amyloid precursor protein catabolic process GO:0042987 5 5 1,000 3,771E-04 0,01240953 ! heart looping GO:0001947 5 5 1,000 3,771E-04 0,01219182 ! endocrine pancreas development GO:0031018 5 5 1,000 3,771E-04 0,01198162 ! indolalkylamine metabolic process GO:0006586 5 5 1,000 3,771E-04 0,01177854 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! sister chromatid cohesion GO:0007062 5 5 1,000 3,771E-04 0,01158223 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 3,771E-04 0,01139236 ! receptor clustering GO:0043113 5 5 1,000 3,771E-04 0,01120861 ! protein heterooligomerization GO:0051291 5 5 1,000 3,771E-04 0,01103069 ! response to amine stimulus GO:0014075 5 5 1,000 3,771E-04 0,01085834 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 1,000 3,771E-04 0,01069129 ! decidualization GO:0046697 5 5 1,000 3,771E-04 0,0105293 ! hair follicle maturation GO:0048820 5 5 1,000 3,771E-04 0,01037214 ! T cell lineage commitment GO:0002360 5 5 1,000 3,771E-04 0,01021961 ! regulation of DNA replication initiation GO:0030174 5 5 1,000 3,771E-04 0,0100715 ! peptidyl-lysine modification GO:0018205 5 5 1,000 3,771E-04 9,928E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 3,771E-04 9,788E-03 ! lymphocyte activation during immune response GO:0002285 5 5 1,000 3,771E-04 9,652E-03 ! blastocyst formation GO:0001825 5 5 1,000 3,771E-04 9,52E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 3,771E-04 9,391E-03 ! positive regulation of smooth muscle contraction GO:0045987 5 5 1,000 3,771E-04 9,266E-03 ! regulation of action potential GO:0001508 24 24 2,000 4,201E-04 0,01018701 ! glucose homeostasis GO:0042593 24 24 2,000 4,201E-04 0,01005471 GO:0033500|carbohydrate homeostasis, ! androgen receptor signaling pathway GO:0030521 24 24 2,000 4,201E-04 9,926E-03 ! heart morphogenesis GO:0003007 25 25 2,000 4,753E-04 0,01108815 ! alcohol biosynthetic process GO:0046165 25 25 2,000 4,753E-04 0,01094955 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 5,634E-04 0,01281806 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 5,634E-04 0,01266174 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 5,634E-04 0,01250919 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 5,634E-04 0,01236027 ! ER overload response GO:0006983 6 6 1,000 5,634E-04 0,01221486 ! focal adhesion formation GO:0048041 7 6 1,000 5,634E-04 0,01207282 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 5,634E-04 0,01193406 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 5,634E-04 0,01179844 ! regulation of bone resorption GO:0045124 6 6 1,000 5,634E-04 0,01166587 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 5,634E-04 0,01153625 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 5,634E-04 0,01140948 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 1,000 5,634E-04 0,01128547 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 5,634E-04 0,01116412 ! nitric oxide metabolic process GO:0046209 6 6 1,000 5,634E-04 0,01104535 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 1,000 5,634E-04 0,01092908 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 5,634E-04 0,01081524 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! maternal placenta development GO:0001893 6 6 1,000 5,634E-04 0,01070374 ! regulation of embryonic development GO:0045995 6 6 1,000 5,634E-04 0,01059452 ! localization within membrane GO:0051668 6 6 1,000 5,634E-04 0,0104875 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 5,992E-04 0,01104338 ! monocarboxylic acid transport GO:0015718 27 27 2,000 5,992E-04 0,01093404 ! angiogenesis GO:0001525 65 64 3,000 6,403E-04 0,01156902 ! carbohydrate transport GO:0008643 28 28 2,000 6,682E-04 0,01195618 ! positive regulation of cellular component organization GO:0051130 65 65 3,000 6,792E-04 0,01203596 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 7,197E-04 0,01263314 ! positive regulation of cell cycle GO:0045787 29 29 2,000 7,421E-04 0,01290204 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 7,421E-04 0,01278146 ! response to UV GO:0009411 29 29 2,000 7,421E-04 0,01266312 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 7,856E-04 0,01328257 ! visual behavior GO:0007632 7 7 1,000 7,856E-04 0,01316182 GO:0008542|visual learning, ! startle response GO:0001964 7 7 1,000 7,856E-04 0,01304325 ! amyloid precursor protein metabolic process GO:0042982 7 7 1,000 7,856E-04 0,01292679 ! response to X-ray GO:0010165 7 7 1,000 7,856E-04 0,01281239 ! regulation of intracellular pH GO:0051453 7 7 1,000 7,856E-04 0,0127 ! response to gamma radiation GO:0010332 8 7 1,000 7,856E-04 0,01258957 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 7,856E-04 0,01248104 ! dopamine metabolic process GO:0042417 7 7 1,000 7,856E-04 0,01237436 ! regulation of mRNA stability GO:0043488 7 7 1,000 7,856E-04 0,0122695 ! negative regulation of T cell activation GO:0050868 7 7 1,000 7,856E-04 0,01216639 ! keratinocyte proliferation GO:0043616 7 7 1,000 7,856E-04 0,012065 ! membrane protein ectodomain proteolysis GO:0006509 7 7 1,000 7,856E-04 0,01196529 GO:0033619|membrane protein proteolysis, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 7,856E-04 0,01186722 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 7,856E-04 0,01177074 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 1,000 7,856E-04 0,01167581 ! axon cargo transport GO:0008088 7 7 1,000 7,856E-04 0,0115824 ! leukocyte activation during immune response GO:0002366 7 7 1,000 7,856E-04 0,01149048 GO:0002263|cell activation during immune response, ! response to radiation GO:0009314 70 68 3,000 8,059E-04 0,01169578 ! positive regulation of transport GO:0051050 71 70 3,000 8,992E-04 0,01294739 ! wound healing GO:0042060 74 70 3,000 8,992E-04 0,01284703 ! B cell activation GO:0042113 31 31 2,000 9,049E-04 0,0128293 ! aging GO:0007568 32 31 2,000 9,049E-04 0,01273137 ! regulation of intracellular transport GO:0032386 31 31 2,000 9,049E-04 0,01263492 ! regulation of cell migration GO:0030334 71 71 3,000 9,486E-04 0,01314496 ! nuclear export GO:0051168 32 32 2,000 9,942E-04 0,01367428 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,043E-03 0,01424255 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 1,000 1,043E-03 0,01413783 ! pancreas development GO:0031016 8 8 1,000 1,043E-03 0,01403463 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,043E-03 0,01393293 ! sex determination GO:0007530 8 8 1,000 1,043E-03 0,01383269 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,043E-03 0,01373389 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,043E-03 0,01363648 ! regulation of RNA stability GO:0043487 8 8 1,000 1,043E-03 0,01354045 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,043E-03 0,01344576 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,043E-03 0,01335239 ! positive regulation of calcium ion transport GO:0051928 8 8 1,000 1,043E-03 0,0132603 GO:0043270|positive regulation of ion transport, ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,043E-03 0,01316948 ! regulation of protein catabolic process GO:0042176 35 34 2,000 1,189E-03 0,01490819 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,336E-03 0,01663715 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,336E-03 0,01652549 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,336E-03 0,01641532 ! phospholipid catabolic process GO:0009395 9 9 1,000 1,336E-03 0,01630661 ! regulation of postsynaptic membrane potential GO:0060078 9 9 1,000 1,336E-03 0,01619933 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,336E-03 0,01609345 ! response to ethanol GO:0045471 9 9 1,000 1,336E-03 0,01598895 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,336E-03 0,0158858 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,336E-03 0,01578397 ! DNA replication initiation GO:0006270 9 9 1,000 1,336E-03 0,01568343 ! regulation of cellular pH GO:0030641 9 9 1,000 1,336E-03 0,01558417 ! histone acetylation GO:0016573 9 9 1,000 1,336E-03 0,01548615 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,336E-03 0,01538937 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,336E-03 0,01529378 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,336E-03 0,01519937 ! microtubule-based movement GO:0007018 82 78 3,000 1,349E-03 0,01525526 ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 1,407E-03 0,01580628 ! regulation of locomotion GO:0040012 79 79 3,000 1,415E-03 0,01580249 ! nuclear transport GO:0051169 79 79 3,000 1,415E-03 0,0157073 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 3,000 1,415E-03 0,01561324 ! regulation of transcription factor activity GO:0051090 38 37 2,000 1,524E-03 0,01671859 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 2,000 1,524E-03 0,01661967 ! lung development GO:0030324 38 37 2,000 1,524E-03 0,0165219 ! cell-matrix adhesion GO:0007160 39 38 2,000 1,647E-03 0,01775586 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 1,647E-03 0,01765262 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 1,663E-03 0,01772067 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,663E-03 0,01761882 ! inositol metabolic process GO:0006020 10 10 1,000 1,663E-03 0,01751814 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,663E-03 0,01741861 ! fat cell differentiation GO:0045444 10 10 1,000 1,663E-03 0,0173202 ! cell-substrate junction assembly GO:0007044 11 10 1,000 1,663E-03 0,01722289 ! neuromuscular junction development GO:0007528 10 10 1,000 1,663E-03 0,01712668 ! embryo implantation GO:0007566 11 10 1,000 1,663E-03 0,01703153 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 1,663E-03 0,01693743 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,663E-03 0,01684437 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 1,663E-03 0,01675232 ! protein stabilization GO:0050821 10 10 1,000 1,663E-03 0,01666128 ! blood vessel morphogenesis GO:0048514 84 83 3,000 1,699E-03 0,01692881 ! respiratory tube development GO:0030323 40 39 2,000 1,777E-03 0,01760761 ! respiratory system development GO:0060541 40 39 2,000 1,777E-03 0,01751345 ! developmental maturation GO:0021700 39 39 2,000 1,777E-03 0,01742029 ! lymphocyte differentiation GO:0030098 39 39 2,000 1,777E-03 0,01732812 ! protein oligomerization GO:0051259 39 39 2,000 1,777E-03 0,01723692 ! positive regulation of cell differentiation GO:0045597 87 85 3,000 1,856E-03 0,01790454 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 1,913E-03 0,01836049 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 1,937E-03 0,01849956 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 2,025E-03 0,01923759 ! signal complex assembly GO:0007172 11 11 1,000 2,025E-03 0,01913894 ! endothelial cell migration GO:0043542 11 11 1,000 2,025E-03 0,01904129 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,025E-03 0,01894463 ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 2,025E-03 0,01884895 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! cellular response to starvation GO:0009267 11 11 1,000 2,025E-03 0,01875423 ! mitotic spindle organization GO:0007052 11 11 1,000 2,025E-03 0,01866046 ! response to lipopolysaccharide GO:0032496 11 11 1,000 2,025E-03 0,01856763 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,025E-03 0,01847571 ! intermediate filament-based process GO:0045103 11 11 1,000 2,025E-03 0,01838469 ! interaction with host GO:0051701 11 11 1,000 2,025E-03 0,01829457 ! membrane depolarization GO:0051899 11 11 1,000 2,025E-03 0,01820533 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,025E-03 0,01811695 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 2,025E-03 0,01802943 GO:0006109|regulation of carbohydrate metabolic process, ! muscle maintenance GO:0046716 12 11 1,000 2,025E-03 0,01794275 ! vitamin A metabolic process GO:0006776 11 11 1,000 2,025E-03 0,0178569 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,025E-03 0,01777187 ! cell cycle checkpoint GO:0000075 42 41 2,000 2,055E-03 0,01794806 ! positive regulation of transferase activity GO:0051347 91 88 3,000 2,108E-03 0,01832751 GO:0033674|positive regulation of kinase activity, ! negative regulation of cell cycle GO:0045786 92 91 3,000 2,384E-03 0,02062588 ! xenobiotic metabolic process GO:0006805 12 12 1,000 2,42E-03 0,02084475 ! glutamate signaling pathway GO:0007215 12 12 1,000 2,42E-03 0,0207478 ! regulation of muscle cell differentiation GO:0051147 13 12 1,000 2,42E-03 0,02065174 ! glycoprotein catabolic process GO:0006516 13 12 1,000 2,42E-03 0,02055657 ! regulation of chromosome organization GO:0033044 12 12 1,000 2,42E-03 0,02046228 ! somitogenesis GO:0001756 13 12 1,000 2,42E-03 0,02036884 ! fat-soluble vitamin metabolic process GO:0006775 12 12 1,000 2,42E-03 0,02027626 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 2,42E-03 0,02018451 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 2,42E-03 0,02009359 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 2,42E-03 0,02000348 ! blood vessel development GO:0001568 95 94 3,000 2,683E-03 0,02207724 ! regulation of DNA binding GO:0051101 47 45 2,000 2,688E-03 0,02201929 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 2,688E-03 0,02192186 ! positive regulation of DNA replication GO:0045740 14 13 1,000 2,849E-03 0,02313198 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 2,849E-03 0,02303052 ! phenol metabolic process GO:0018958 13 13 1,000 2,849E-03 0,02292995 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 1,000 2,849E-03 0,02283025 ! vasculogenesis GO:0001570 13 13 1,000 2,849E-03 0,02273142 ! mitochondrial membrane organization GO:0007006 13 13 1,000 2,849E-03 0,02263344 ! actin filament bundle formation GO:0051017 13 13 1,000 2,849E-03 0,0225363 ! cell aging GO:0007569 13 13 1,000 2,849E-03 0,02243999 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,849E-03 0,0223445 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 2,849E-03 0,02224982 ! positive regulation of locomotion GO:0040017 13 13 1,000 2,849E-03 0,02215594 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! long-chain fatty acid transport GO:0015909 13 13 1,000 2,849E-03 0,02206285 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,849E-03 0,02197054 ! response to cytokine stimulus GO:0034097 13 13 1,000 2,849E-03 0,02187899 ! blastocyst development GO:0001824 13 13 1,000 2,849E-03 0,02178821 ! vasculature development GO:0001944 97 96 3,000 2,897E-03 0,02206084 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 3,122E-03 0,02367543 ! actin filament organization GO:0007015 50 48 2,000 3,234E-03 0,02442916 ! pyruvate metabolic process GO:0006090 14 14 1,000 3,311E-03 0,02490563 ! protein amino acid acylation GO:0043543 14 14 1,000 3,311E-03 0,02480438 ! hair cycle GO:0042633 14 14 1,000 3,311E-03 0,02470396 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! regulation of behavior GO:0050795 14 14 1,000 3,311E-03 0,02460435 ! base-excision repair GO:0006284 14 14 1,000 3,311E-03 0,02450554 ! response to molecule of bacterial origin GO:0002237 14 14 1,000 3,311E-03 0,02440751 ! muscle organ development GO:0007517 102 100 3,000 3,358E-03 0,02465763 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 3,358E-03 0,02455978 ! hemopoiesis GO:0030097 104 100 3,000 3,358E-03 0,02446271 ! gland development GO:0048732 51 49 2,000 3,43E-03 0,02488972 ! cell cycle arrest GO:0007050 49 49 2,000 3,43E-03 0,02479212 ! cellular lipid catabolic process GO:0044242 50 49 2,000 3,43E-03 0,02469527 ! skeletal muscle tissue development GO:0007519 50 49 2,000 3,43E-03 0,02459918 GO:0060538|skeletal muscle organ development, ! protein import into nucleus, translocation GO:0000060 15 15 1,000 3,805E-03 0,02718132 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 3,805E-03 0,02707638 ! regulation of smooth muscle contraction GO:0006940 15 15 1,000 3,805E-03 0,02697224 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 3,805E-03 0,02686889 ! response to starvation GO:0042594 15 15 1,000 3,805E-03 0,02676634 ! response to ionizing radiation GO:0010212 16 15 1,000 3,805E-03 0,02666457 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 3,805E-03 0,02656357 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 3,805E-03 0,02646333 ! cell fate commitment GO:0045165 52 52 2,000 4,062E-03 0,02814066 ! response to hypoxia GO:0001666 53 53 2,000 4,287E-03 0,02958892 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 4,331E-03 0,02978701 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of synaptic plasticity GO:0048167 16 16 1,000 4,331E-03 0,02967628 ! spliceosomal snRNP biogenesis GO:0000387 16 16 1,000 4,331E-03 0,02956637 ! learning GO:0007612 16 16 1,000 4,331E-03 0,02945727 ! positive regulation of mitosis GO:0045840 16 16 1,000 4,331E-03 0,02934897 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 4,331E-03 0,02924146 ! segmentation GO:0035282 17 16 1,000 4,331E-03 0,02913474 ! fatty acid beta-oxidation GO:0006635 16 16 1,000 4,331E-03 0,0290288 ! cellular response to nutrient levels GO:0031669 16 16 1,000 4,331E-03 0,02892362 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 4,331E-03 0,02881921 ! polyol metabolic process GO:0019751 16 16 1,000 4,331E-03 0,02871554 ! positive regulation of catabolic process GO:0009896 16 16 1,000 4,331E-03 0,02861262 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 4,331E-03 0,02851043 ! response to oxygen levels GO:0070482 55 54 2,000 4,519E-03 0,0296399 ! in utero embryonic development GO:0001701 55 55 2,000 4,759E-03 0,03110375 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 4,89E-03 0,03184294 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 4,89E-03 0,03173082 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 4,89E-03 0,03161949 ! myelination GO:0042552 17 17 1,000 4,89E-03 0,03150893 ! regulation of transmembrane transport GO:0034762 17 17 1,000 4,89E-03 0,03139914 ! cell junction assembly GO:0034329 18 17 1,000 4,89E-03 0,03129012 ! tissue remodeling GO:0048771 17 17 1,000 4,89E-03 0,03118185 ! negative regulation of cell development GO:0010721 18 17 1,000 4,89E-03 0,03107432 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 4,89E-03 0,03096754 ! regulation of calcium ion transport GO:0051924 17 17 1,000 4,89E-03 0,03086148 ! reproductive developmental process GO:0003006 56 56 2,000 5,007E-03 0,03149388 ! regulation of binding GO:0051098 60 57 2,000 5,262E-03 0,03298737 ! regulation of cell projection organization GO:0031344 19 18 1,000 5,479E-03 0,03423033 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 5,479E-03 0,03411469 ! meiosis I GO:0007127 18 18 1,000 5,479E-03 0,03399982 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 5,479E-03 0,03388573 ! regulation of metal ion transport GO:0010959 18 18 1,000 5,479E-03 0,0337724 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 5,479E-03 0,03365982 ! negative regulation of DNA binding GO:0043392 19 18 1,000 5,479E-03 0,033548 ! hexose biosynthetic process GO:0019319 18 18 1,000 5,479E-03 0,03343691 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 5,479E-03 0,03332656 ! regulation of microtubule-based process GO:0032886 18 18 1,000 5,479E-03 0,03321693 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 5,479E-03 0,03310802 ! carboxylic acid transport GO:0046942 59 59 2,000 5,796E-03 0,03490956 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 2,000 5,796E-03 0,03479585 ! DNA damage checkpoint GO:0000077 19 19 1,000 6,099E-03 0,03649797 ! regulation of pH GO:0006885 19 19 1,000 6,099E-03 0,03637985 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 6,099E-03 0,03626249 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 6,099E-03 0,0361459 ! peripheral nervous system development GO:0007422 19 19 1,000 6,099E-03 0,03603004 ! regulation of protein stability GO:0031647 19 19 1,000 6,099E-03 0,03591493 ! regulation of cell shape GO:0008360 21 19 1,000 6,099E-03 0,03580055 ! response to heat GO:0009408 19 19 1,000 6,099E-03 0,0356869 ! lipid transport GO:0006869 62 62 2,000 6,656E-03 0,03882056 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 6,656E-03 0,0386981 ! negative regulation of binding GO:0051100 21 20 1,000 6,75E-03 0,03912299 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 6,75E-03 0,03900035 ! lipid oxidation GO:0034440 20 20 1,000 6,75E-03 0,03887847 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 1,000 6,75E-03 0,03875736 ! glucose metabolic process GO:0006006 63 63 2,000 6,959E-03 0,03982949 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 7,432E-03 0,04240385 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 7,432E-03 0,04227298 ! mammary gland development GO:0030879 23 21 1,000 7,432E-03 0,04214291 ! Notch signaling pathway GO:0007219 22 21 1,000 7,432E-03 0,04201363 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 7,432E-03 0,04188515 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 7,432E-03 0,04175745 ! negative regulation of protein transport GO:0051224 21 21 1,000 7,432E-03 0,04163053 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 7,916E-03 0,04420705 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 8,143E-03 0,04533736 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 1,000 8,143E-03 0,0452008 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 8,143E-03 0,04506506 ! sister chromatid segregation GO:0000819 22 22 1,000 8,143E-03 0,04493014 ! regulation of ion transport GO:0043269 22 22 1,000 8,143E-03 0,04479602 ! cell junction organization GO:0034330 23 22 1,000 8,143E-03 0,0446627 ! maintenance of protein location in cell GO:0032507 23 22 1,000 8,143E-03 0,04453017 ! fatty acid catabolic process GO:0009062 23 22 1,000 8,143E-03 0,04439842 ! cytokinesis GO:0000910 23 22 1,000 8,143E-03 0,04426745 ! striated muscle tissue development GO:0014706 69 67 2,000 8,251E-03 0,04472449 ! regulation of cell size GO:0008361 68 68 2,000 8,594E-03 0,04645045 ! epithelial cell differentiation GO:0030855 23 23 1,000 8,883E-03 0,04786864 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 8,883E-03 0,04772908 ! endocrine system development GO:0035270 23 23 1,000 8,883E-03 0,04759033 ! positive regulation of growth GO:0045927 23 23 1,000 8,883E-03 0,04745239 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 8,883E-03 0,04731524 ! lipid homeostasis GO:0055088 23 23 1,000 8,883E-03 0,04717889 ! calcium-mediated signaling GO:0019722 23 23 1,000 8,883E-03 0,04704331 ! cell projection assembly GO:0030031 25 23 1,000 8,883E-03 0,04690852 ! response to nutrient levels GO:0031667 69 69 2,000 8,946E-03 0,04710925 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 8,946E-03 0,04697503 ! growth GO:0040007 70 70 2,000 9,307E-03 0,04872815 ! muscle tissue development GO:0060537 72 70 2,000 9,307E-03 0,04859011 ! mitochondrial transport GO:0006839 24 24 1,000 9,652E-03 0,05025133 ! T cell differentiation GO:0030217 24 24 1,000 9,652E-03 0,05010977 ! maintenance of protein location GO:0045185 25 24 1,000 9,652E-03 0,04996902 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,01005267 0,05189658 ! response to extracellular stimulus GO:0009991 72 72 2,000 0,01005267 0,05175162 ! endosome transport GO:0016197 25 25 1,000 0,01045017 0,05364809 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01045017 0,05349907 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01045017 0,05335087 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01045017 0,0532035 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01045017 0,05305693 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01045017 0,05291117 ! positive regulation of binding GO:0051099 27 26 1,000 0,01127644 0,0569383 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01127644 0,05678273 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01127644 0,05662801 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01127644 0,05647413 ! double-strand break repair GO:0006302 27 26 1,000 0,01127644 0,05632108 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01127644 0,05616886 ! synapse organization GO:0050808 26 26 1,000 0,01127644 0,05601746 ! learning or memory GO:0007611 28 27 1,000 0,01213062 0,06009873 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,01213062 0,05993761 ! activation of caspase activity GO:0006919 27 27 1,000 0,01213062 0,05977735 ! isoprenoid metabolic process GO:0006720 27 27 1,000 0,01213062 0,05961794 ! cell growth GO:0016049 27 27 1,000 0,01213062 0,05945939 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 0,01249556 0,0610857 ! neuromuscular process GO:0050905 28 28 1,000 0,01301234 0,06344378 ! regulation of muscle contraction GO:0006937 28 28 1,000 0,01301234 0,06327638 ! histone modification GO:0016570 28 28 1,000 0,01301234 0,06310986 ! developmental growth GO:0048589 28 28 1,000 0,01301234 0,06294422 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01301234 0,06277944 ! tube development GO:0035295 83 81 2,000 0,01383395 0,06656909 ! lymphocyte activation GO:0046649 82 81 2,000 0,01383395 0,06639574 ! lipid catabolic process GO:0016042 82 81 2,000 0,01383395 0,06622328 ! viral reproductive process GO:0022415 29 29 1,000 0,01392125 0,06646857 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01392125 0,06629682 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,01392125 0,06612595 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01392125 0,06595596 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01392125 0,06578684 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01485699 0,07002924 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01485699 0,06985059 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01485699 0,06967286 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01485699 0,06949602 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01485699 0,06932008 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01485699 0,06914503 ! regulation of cellular localization GO:0060341 86 85 2,000 0,01574136 0,0730764 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,0158192 0,07325323 ! regulation of translational initiation GO:0006446 31 31 1,000 0,0158192 0,07306964 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,0158192 0,07288696 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,0162403 0,0746406 ! hexose metabolic process GO:0019318 87 86 2,000 0,0162403 0,07445493 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,01680753 0,07686422 ! muscle fiber development GO:0048747 32 32 1,000 0,01680753 0,07667396 ! lipid modification GO:0030258 32 32 1,000 0,01680753 0,07648465 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01680753 0,07629626 ! cell maturation GO:0048469 32 32 1,000 0,01680753 0,0761088 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01680753 0,07592226 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01680753 0,07573663 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01680753 0,07555191 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 0,01680753 0,07536808 ! maintenance of location GO:0051235 33 32 1,000 0,01680753 0,07518515 ! negative regulation of cell size GO:0045792 33 33 1,000 0,01782164 0,07952852 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,01782164 0,07933642 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,01782164 0,07914525 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,01886117 0,08356043 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,01886117 0,08336004 ! viral reproduction GO:0016032 34 34 1,000 0,01886117 0,08316062 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,01992579 0,08764495 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,01992579 0,08743627 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01992579 0,08722858 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,01992579 0,08702188 ! regulation of mitosis GO:0007088 37 36 1,000 0,02101516 0,09156251 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,02101516 0,09134656 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,02101516 0,09113162 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,02101516 0,0909177 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,02101516 0,09070478 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02101516 0,09049285 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02212894 0,09506676 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! negative regulation of growth GO:0045926 37 37 1,000 0,02212894 0,09484567 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,02212894 0,09462561 ! adaptive immune response GO:0002250 37 37 1,000 0,02212894 0,09440657 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! blood circulation GO:0008015 99 98 2,000 0,02292326 0,09756942 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 2,000 0,02292326 0,09734461 ! urogenital system development GO:0001655 38 38 1,000 0,0232668 0,09857636 ! axon guidance GO:0007411 39 38 1,000 0,0232668 0,09835026 ! regulation of neurological system process GO:0031644 38 38 1,000 0,0232668 0,09812521 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,0232668 0,09790118 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,02442841 0,10255481 ! activation of MAPK activity GO:0000187 39 39 1,000 0,02442841 0,10232174 ! response to unfolded protein GO:0006986 39 39 1,000 0,02442841 0,10208971 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,02442841 0,10185874 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,02442841 0,10162881 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,02561345 0,10631888 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,02561345 0,10607996 ! organelle localization GO:0051640 41 40 1,000 0,02561345 0,10584211 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,02682158 0,11058652 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of caspase activity GO:0043281 41 41 1,000 0,02682158 0,11033967 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,0280525 0,11514643 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,0280525 0,11489055 ! response to protein stimulus GO:0051789 42 42 1,000 0,0280525 0,11463581 ! reproductive structure development GO:0048608 43 43 1,000 0,02930587 0,11949274 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,02930587 0,11922896 ! mitochondrion organization GO:0007005 44 43 1,000 0,02930587 0,11896634 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,02930587 0,11870488 ! mRNA transport GO:0051028 44 44 1,000 0,03058139 0,1235998 ! protein import into nucleus GO:0006606 44 44 1,000 0,03058139 0,12332934 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,03058139 0,12306006 ! vitamin metabolic process GO:0006766 44 44 1,000 0,03058139 0,12279196 ! rRNA transcription GO:0009303 5 5 0,000 0,03087067 0,12368402 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03087067 0,12341572 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03087067 0,12314859 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03087067 0,12288261 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03087067 0,12261778 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03087067 0,12235408 ! reproductive cellular process GO:0048610 5 5 0,000 0,03087067 0,12209152 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03087067 0,12183008 ! metencephalon development GO:0022037 5 5 0,000 0,03087067 0,12156976 ! water transport GO:0006833 5 5 0,000 0,03087067 0,12131055 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03087067 0,12105244 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03087067 0,12079543 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03087067 0,12053951 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03087067 0,12028467 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03087067 0,1200309 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03087067 0,11977821 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03087067 0,11952657 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03087067 0,11927599 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03087067 0,11902646 ! filopodium assembly GO:0046847 7 5 0,000 0,03087067 0,11877797 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03087067 0,11853052 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03087067 0,11828409 ! GTP metabolic process GO:0046039 5 5 0,000 0,03087067 0,11803869 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03087067 0,1177943 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03087067 0,11755093 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03087067 0,11730855 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03087067 0,11706718 ! social behavior GO:0035176 5 5 0,000 0,03087067 0,11682679 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03087067 0,11658739 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03087067 0,11634897 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03087067 0,11611153 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03087067 0,11587505 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03087067 0,11563953 ! hippocampus development GO:0021766 6 5 0,000 0,03087067 0,11540497 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03087067 0,11517135 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03087067 0,11493868 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03087067 0,11470695 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03087067 0,11447615 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03087067 0,11424628 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03087067 0,11401733 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03087067 0,1137893 ! pH reduction GO:0045851 5 5 0,000 0,03087067 0,11356217 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03087067 0,11333595 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03087067 0,11311063 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03087067 0,11288621 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03087067 0,11266267 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03087067 0,11244002 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03087067 0,11221824 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03087067 0,11199734 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03087067 0,11177731 ! adrenal gland development GO:0030325 5 5 0,000 0,03087067 0,11155813 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03087067 0,11133982 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03087067 0,11112236 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03087067 0,11090575 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03087067 0,11068998 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03087067 0,11047505 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03087067 0,11026095 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03087067 0,11004768 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03087067 0,10983523 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03087067 0,1096236 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03087067 0,10941279 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03087067 0,10920278 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03087067 0,10899358 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03087067 0,10878518 ! muscle cell migration GO:0014812 5 5 0,000 0,03087067 0,10857757 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03087067 0,10837076 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03087067 0,10816473 GO:0021952|central nervous system projection neuron axonogenesis, ! response to ATP GO:0033198 5 5 0,000 0,03087067 0,10795948 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03087067 0,10775502 ! regulation of appetite GO:0032098 5 5 0,000 0,03087067 0,10755132 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03087067 0,10734839 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03087067 0,10714623 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03087067 0,10694483 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03087067 0,10674418 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03087067 0,10654429 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03087067 0,10634514 ! fear response GO:0042596 5 5 0,000 0,03087067 0,10614673 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03087067 0,10594907 ! retinol metabolic process GO:0042572 5 5 0,000 0,03087067 0,10575213 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03087067 0,10555593 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03087067 0,10536046 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03087067 0,10516571 ! parturition GO:0007567 5 5 0,000 0,03087067 0,10497168 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03087067 0,10477836 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03087067 0,10458575 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03087067 0,10439385 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03087067 0,10420265 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03087067 0,10401215 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03087067 0,10382235 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03087067 0,10363324 ! response to UV-B GO:0010224 5 5 0,000 0,03087067 0,10344482 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03087067 0,10325708 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03087067 0,10307002 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03087067 0,10288363 ! interaction with symbiont GO:0051702 5 5 0,000 0,03087067 0,10269792 ! cellular extravasation GO:0045123 5 5 0,000 0,03087067 0,10251288 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03087067 0,1023285 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03087067 0,10214479 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03087067 0,10196174 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03087067 0,10177934 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03087067 0,10159759 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03087067 0,10141649 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03087067 0,10123603 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03087067 0,10105621 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03087067 0,10087704 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03087067 0,10069849 ! neuron recognition GO:0008038 5 5 0,000 0,03087067 0,10052058 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03087067 0,1003433 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03087067 0,10016663 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03087067 0,09999059 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03087067 0,09981517 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03087067 0,09964036 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03087067 0,09946617 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03087067 0,09929258 ! postreplication repair GO:0006301 5 5 0,000 0,03087067 0,0991196 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03087067 0,09894721 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03087067 0,09877543 ! histone methylation GO:0016571 5 5 0,000 0,03087067 0,09860424 ! DNA methylation GO:0006306 5 5 0,000 0,03087067 0,09843365 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03087067 0,09826364 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03087067 0,09809422 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03087067 0,09792538 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03087067 0,09775713 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03087067 0,09758945 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03087067 0,09742234 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03087067 0,09725581 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03087067 0,09708984 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03087067 0,09692444 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03087067 0,09675961 ! sterol catabolic process GO:0016127 5 5 0,000 0,03087067 0,09659533 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03087067 0,09643161 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03087067 0,09626844 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03087067 0,09610582 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03087067 0,09594376 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! zymogen activation GO:0031638 5 5 0,000 0,03087067 0,09578224 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03087067 0,09562126 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03087067 0,09546082 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03087067 0,09530092 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03087067 0,09514155 ! nucleosome positioning GO:0016584 5 5 0,000 0,03087067 0,09498272 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03087067 0,09482441 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03087067 0,09466664 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03087067 0,09450938 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03087067 0,09435265 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03087067 0,09419644 ! NADPH regeneration GO:0006740 5 5 0,000 0,03087067 0,09404074 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03087067 0,09388556 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03087067 0,09373089 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03087067 0,09357672 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03087067 0,09342307 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03087067 0,09326992 ! sarcomere organization GO:0045214 5 5 0,000 0,03087067 0,09311726 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03087067 0,09296511 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03087067 0,09281346 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03087067 0,09266229 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03087067 0,09251162 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03087067 0,09236144 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03087067 0,09221175 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03087067 0,09206254 ! spleen development GO:0048536 5 5 0,000 0,03087067 0,09191381 ! male genitalia development GO:0030539 5 5 0,000 0,03087067 0,09176556 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03087067 0,09161779 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03087067 0,0914705 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03087067 0,09132367 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03087067 0,09117732 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03087067 0,09103144 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03087067 0,09088602 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03087067 0,09074107 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03087067 0,09059657 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03087067 0,09045254 ! ATP catabolic process GO:0006200 5 5 0,000 0,03087067 0,09030897 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03087067 0,09016585 GO:0007439|ectodermal gut development, ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03087067 0,09002318 ! embryonic gut development GO:0048566 5 5 0,000 0,03087067 0,08988096 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03087067 0,08973919 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03087067 0,08959787 ! activation of innate immune response GO:0002218 5 5 0,000 0,03087067 0,08945699 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03087067 0,08931656 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03087067 0,08917656 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03087067 0,08903701 ! muscle adaptation GO:0043500 5 5 0,000 0,03087067 0,08889789 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03087067 0,0887592 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03087067 0,08862095 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03087067 0,08848312 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03087067 0,08834573 ! defense response to fungus GO:0050832 5 5 0,000 0,03087067 0,08820876 ! lysogeny GO:0030069 5 5 0,000 0,03087067 0,08807221 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03087067 0,08793609 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03087067 0,08780038 ! response to nicotine GO:0035094 5 5 0,000 0,03087067 0,0876651 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03087067 0,08753023 ! mitochondrion localization GO:0051646 5 5 0,000 0,03087067 0,08739577 ! nucleus localization GO:0051647 5 5 0,000 0,03087067 0,08726173 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03087067 0,0871281 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,03187875 0,08983569 ! nuclear import GO:0051170 45 45 1,000 0,03187875 0,08969853 ! protein processing GO:0016485 45 45 1,000 0,03187875 0,0895618 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,03319764 0,09312518 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,03319764 0,09298365 ! regulation of blood pressure GO:0008217 48 47 1,000 0,03453774 0,09659037 ! sex differentiation GO:0007548 47 47 1,000 0,03453774 0,09644403 ! calcium ion transport GO:0006816 48 48 1,000 0,03589876 0,10009292 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,03589876 0,09994172 ! protein localization in nucleus GO:0034504 48 48 1,000 0,03589876 0,09979098 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03693214 0,10250892 ! axon extension GO:0048675 7 6 0,000 0,03693214 0,10235478 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03693214 0,10220109 ! tRNA modification GO:0006400 6 6 0,000 0,03693214 0,10204786 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03693214 0,1018951 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03693214 0,10174279 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03693214 0,10159093 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03693214 0,10143953 ! regulation of S phase GO:0033261 6 6 0,000 0,03693214 0,10128858 ! myotube differentiation GO:0014902 6 6 0,000 0,03693214 0,10113808 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03693214 0,10098802 ! bone remodeling GO:0046849 6 6 0,000 0,03693214 0,10083841 ! N-glycan processing GO:0006491 6 6 0,000 0,03693214 0,10068924 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,03693214 0,10054051 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03693214 0,10039222 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03693214 0,10024437 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03693214 0,10009695 ! RNA methylation GO:0001510 6 6 0,000 0,03693214 0,09994996 ! cartilage condensation GO:0001502 7 6 0,000 0,03693214 0,09980341 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03693214 0,09965728 ! succinate metabolic process GO:0006105 7 6 0,000 0,03693214 0,09951159 ! artery development GO:0060840 6 6 0,000 0,03693214 0,09936631 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03693214 0,09922147 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03693214 0,09907704 ! androgen metabolic process GO:0008209 6 6 0,000 0,03693214 0,09893303 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03693214 0,09878944 ! limbic system development GO:0021761 7 6 0,000 0,03693214 0,09864627 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03693214 0,09850351 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03693214 0,09836116 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03693214 0,09821923 ! pathogenesis GO:0009405 6 6 0,000 0,03693214 0,0980777 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03693214 0,09793658 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03693214 0,09779587 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03693214 0,09765556 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03693214 0,09751565 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03693214 0,09737615 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03693214 0,09723704 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03693214 0,09709832 ! arginine metabolic process GO:0006525 6 6 0,000 0,03693214 0,09696001 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03693214 0,09682208 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03693214 0,09668455 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03693214 0,09654741 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03693214 0,09641066 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03693214 0,09627429 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03693214 0,09613831 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03693214 0,09600272 ! V(D)J recombination GO:0033151 6 6 0,000 0,03693214 0,0958675 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03693214 0,09573267 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03693214 0,09559821 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03693214 0,09546413 ! regulation of heart rate GO:0002027 6 6 0,000 0,03693214 0,09533043 ! lipid digestion GO:0044241 6 6 0,000 0,03693214 0,0951971 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03693214 0,09506414 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03693214 0,09493156 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03693214 0,09479934 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03693214 0,09466749 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03693214 0,09453601 ! ruffle organization GO:0031529 6 6 0,000 0,03693214 0,09440489 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,03693214 0,09427414 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03693214 0,09414374 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03693214 0,09401371 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03693214 0,09388404 ! L-amino acid transport GO:0015807 6 6 0,000 0,03693214 0,09375472 ! bone mineralization GO:0030282 6 6 0,000 0,03693214 0,09362576 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03693214 0,09349715 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03693214 0,0933689 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03693214 0,09324099 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03693214 0,09311344 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03693214 0,09298624 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03693214 0,09285938 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03693214 0,09273287 ! regulation of organ growth GO:0046620 6 6 0,000 0,03693214 0,0926067 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03693214 0,09248088 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03693214 0,09235539 ! response to dsRNA GO:0043331 6 6 0,000 0,03693214 0,09223025 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03693214 0,09210545 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03693214 0,09198098 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03693214 0,09185685 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03693214 0,09173305 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03693214 0,09160959 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03693214 0,09148646 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03693214 0,09136366 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03693214 0,09124119 ! erythrocyte development GO:0048821 6 6 0,000 0,03693214 0,09111904 ! renal water homeostasis GO:0003091 6 6 0,000 0,03693214 0,09099723 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03693214 0,09087573 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03693214 0,09075457 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03693214 0,09063372 ! ribosome assembly GO:0042255 6 6 0,000 0,03693214 0,0905132 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03693214 0,090393 ! diencephalon development GO:0021536 6 6 0,000 0,03693214 0,09027311 ! fucose catabolic process GO:0019317 6 6 0,000 0,03693214 0,09015354 GO:0042355|L-fucose catabolic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,03693214 0,09003429 ! regulation of cell division GO:0051302 6 6 0,000 0,03693214 0,08991536 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03693214 0,08979674 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03693214 0,08967843 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03693214 0,08956043 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03693214 0,08944274 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03693214 0,08932536 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03693214 0,08920829 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03693214 0,08909153 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03693214 0,08897507 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03693214 0,08885891 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03693214 0,08874306 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03693214 0,08862751 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03693214 0,08851226 ! thymus development GO:0048538 6 6 0,000 0,03693214 0,08839731 ! lymph node development GO:0048535 6 6 0,000 0,03693214 0,08828265 ! organic cation transport GO:0015695 6 6 0,000 0,03693214 0,0881683 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03693214 0,08805424 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03693214 0,08794047 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03693214 0,087827 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03693214 0,08771382 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03693214 0,08760093 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03693214 0,08748834 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03693214 0,08737603 ! alditol metabolic process GO:0019400 6 6 0,000 0,03693214 0,08726401 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03693214 0,08715227 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03693214 0,08704083 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03693214 0,08692966 ! ossification GO:0001503 50 49 1,000 0,0372804 0,08763747 GO:0060348|bone development, ! divalent metal ion transport GO:0070838 49 49 1,000 0,0372804 0,08752583 ! response to nutrient GO:0007584 49 49 1,000 0,0372804 0,08741448 ! response to bacterium GO:0009617 50 49 1,000 0,0372804 0,0873034 ! negative regulation of transport GO:0051051 51 50 1,000 0,03868236 0,09047155 ! RNA transport GO:0050658 50 50 1,000 0,03868236 0,09035689 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 1,000 0,03868236 0,09024251 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,03868236 0,09012843 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,03868236 0,09001463 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,03868236 0,08990112 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,03868236 0,08978789 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,04010434 0,09297144 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,04010434 0,09285464 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,04010434 0,09273814 GO:0051325|interphase, ! protein maturation GO:0051604 51 51 1,000 0,04010434 0,09262192 ! RNA localization GO:0006403 52 52 1,000 0,04154605 0,0958315 ! cholesterol metabolic process GO:0008203 52 52 1,000 0,04154605 0,09571171 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,04154605 0,09559222 ! respiratory burst GO:0045730 7 7 0,000 0,04295656 0,0987144 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04295656 0,09859146 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04295656 0,09846884 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04295656 0,09834652 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04295656 0,0982245 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04295656 0,09810278 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04295656 0,09798137 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04295656 0,09786026 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04295656 0,09773944 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04295656 0,09761892 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04295656 0,0974987 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04295656 0,09737878 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04295656 0,09725915 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04295656 0,09713981 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04295656 0,09702077 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04295656 0,09690202 ! axis specification GO:0009798 7 7 0,000 0,04295656 0,09678355 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04295656 0,09666538 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04295656 0,0965475 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04295656 0,0964299 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04295656 0,09631259 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04295656 0,09619556 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04295656 0,09607882 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04295656 0,09596236 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04295656 0,09584618 ! digestive system development GO:0055123 7 7 0,000 0,04295656 0,09573029 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04295656 0,09561467 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04295656 0,09549933 ! protein targeting to ER GO:0045047 8 7 0,000 0,04295656 0,09538427 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04295656 0,09526949 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04295656 0,09515498 ! endoderm development GO:0007492 7 7 0,000 0,04295656 0,09504075 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04295656 0,09492679 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04295656 0,09481311 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,04295656 0,0946997 ! response to hexose stimulus GO:0009746 7 7 0,000 0,04295656 0,09458655 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04295656 0,09447368 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04295656 0,09436108 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04295656 0,09424875 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04295656 0,09413668 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04295656 0,09402488 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04295656 0,09391334 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04295656 0,09380207 ! UV protection GO:0009650 7 7 0,000 0,04295656 0,09369106 ! DNA integration GO:0015074 7 7 0,000 0,04295656 0,09358031 ! myofibril assembly GO:0030239 7 7 0,000 0,04295656 0,09346983 GO:0055002|striated muscle cell development, ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04295656 0,09335961 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04295656 0,09324964 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04295656 0,09313994 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04295656 0,09303049 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04295656 0,0929213 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04295656 0,09281236 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04295656 0,09270368 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04295656 0,09259526 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04295656 0,09248709 ! eating behavior GO:0042755 7 7 0,000 0,04295656 0,09237917 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04295656 0,0922715 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04295656 0,09216408 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04295656 0,09205691 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04295656 0,09195 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04295656 0,09184333 ! cranial nerve development GO:0021545 7 7 0,000 0,04295656 0,0917369 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04295656 0,09163072 ! induction of an organ GO:0001759 7 7 0,000 0,04295656 0,09152479 ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04295656 0,09141911 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04295656 0,09131366 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04295656 0,09120846 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04295656 0,09110351 ! platelet activation GO:0030168 8 7 0,000 0,04295656 0,09099879 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04295656 0,09089431 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04295656 0,09079008 ! natural killer cell activation GO:0030101 7 7 0,000 0,04295656 0,09068608 ! NADP metabolic process GO:0006739 7 7 0,000 0,04295656 0,09058232 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04295656 0,0904788 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04295656 0,09037551 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04295656 0,09027246 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04295656 0,09016964 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04295656 0,09006706 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04295656 0,08996471 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04295656 0,0898626 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04295656 0,08976071 ! cell-cell recognition GO:0009988 8 7 0,000 0,04295656 0,08965906 ! hormone catabolic process GO:0042447 7 7 0,000 0,04295656 0,08955763 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04295656 0,08945644 ! oxygen transport GO:0015671 7 7 0,000 0,04295656 0,08935547 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04295656 0,08925473 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04295656 0,08915422 ! regulation of axon extension GO:0030516 7 7 0,000 0,04295656 0,08905393 ! cell killing GO:0001906 7 7 0,000 0,04295656 0,08895387 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04295656 0,08885404 ! adult feeding behavior GO:0008343 7 7 0,000 0,04295656 0,08875442 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04295656 0,08865504 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04295656 0,08855587 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04295656 0,08845692 ! response to cold GO:0009409 7 7 0,000 0,04295656 0,0883582 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,0430072 0,08836374 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 0,0430072 0,08826534 ! regulation of T cell activation GO:0050863 53 53 1,000 0,0430072 0,08816716 ! regulation of protein transport GO:0051223 53 53 1,000 0,0430072 0,0880692 GO:0070201|regulation of establishment of protein localization, ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,04448751 0,09099943 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,04598669 0,09396173 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,04598669 0,09385767 ! extracellular structure organization GO:0043062 56 56 1,000 0,04750446 0,09684815 ! regulation of nervous system development GO:0051960 57 56 1,000 0,04750446 0,09674113 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04894418 0,09956304 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04894418 0,09945327 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04894418 0,09934374 ! positive regulation of translation GO:0045727 8 8 0,000 0,04894418 0,09923445 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04894418 0,0991254 ! superoxide anion generation GO:0042554 8 8 0,000 0,04894418 0,0990166 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04894418 0,09890802 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04894418 0,09879969 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04894418 0,0986916 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04894418 0,09858374 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04894418 0,09847611 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04894418 0,09836872 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04894418 0,09826157 ! zinc ion transport GO:0006829 8 8 0,000 0,04894418 0,09815464 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04894418 0,09804795 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04894418 0,0979415 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04894418 0,09783527 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04894418 0,09772927 ! lipid localization GO:0010876 8 8 0,000 0,04894418 0,0976235 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04894418 0,09751797 ! response to cAMP GO:0051591 8 8 0,000 0,04894418 0,09741265 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04894418 0,09730757 GO:0048200|Golgi transport vesicle coating, ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04894418 0,09720271 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04894418 0,09709808 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04894418 0,09699368 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04894418 0,09688949 ! sensory perception of taste GO:0050909 8 8 0,000 0,04894418 0,09678553 ! organelle fusion GO:0048284 8 8 0,000 0,04894418 0,0966818 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04894418 0,09657828 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,04894418 0,09647499 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04894418 0,09637192 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04894418 0,09626907 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04894418 0,09616644 ! sperm motility GO:0030317 8 8 0,000 0,04894418 0,09606402 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04894418 0,09596183 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04894418 0,09585985 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04894418 0,09575809 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04894418 0,09565654 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04894418 0,09555521 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04894418 0,09545409 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04894418 0,09535319 ! Golgi organization GO:0007030 8 8 0,000 0,04894418 0,0952525 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04894418 0,09515202 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04894418 0,09505176 ! fructose metabolic process GO:0006000 8 8 0,000 0,04894418 0,0949517 ! mannose metabolic process GO:0006013 9 8 0,000 0,04894418 0,09485186 ! NAD metabolic process GO:0019674 8 8 0,000 0,04894418 0,09475222 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04894418 0,0946528 ! plasma membrane fusion GO:0045026 8 8 0,000 0,04894418 0,09455358 ! response to fungus GO:0009620 8 8 0,000 0,04894418 0,09445457 ! stem cell differentiation GO:0048863 8 8 0,000 0,04894418 0,09435577 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04894418 0,09425718 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,04894418 0,09415879 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04894418 0,0940606 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04894418 0,09396262 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04894418 0,09386485 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04894418 0,09376727 ! vasoconstriction GO:0042310 8 8 0,000 0,04894418 0,0936699 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04894418 0,09357274 ! muscle cell development GO:0055001 8 8 0,000 0,04894418 0,09347577 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04894418 0,093379 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04894418 0,09328244 ! sensory perception of pain GO:0019233 8 8 0,000 0,04894418 0,09318607 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04894418 0,09308991 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04894418 0,09299394 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04894418 0,09289816 ! chromatin silencing GO:0006342 8 8 0,000 0,04894418 0,09280259 ! tissue regeneration GO:0042246 8 8 0,000 0,04894418 0,09270721 ! salivary gland development GO:0007431 8 8 0,000 0,04894418 0,09261203 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04894418 0,09251704 ! T cell homeostasis GO:0043029 8 8 0,000 0,04894418 0,09242225 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04894418 0,09232765 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,04894418 0,09223325 ! water homeostasis GO:0030104 8 8 0,000 0,04894418 0,09213904 ! cofactor transport GO:0051181 8 8 0,000 0,04894418 0,09204502 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04894418 0,09195119 ! acid secretion GO:0046717 8 8 0,000 0,04894418 0,09185755 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04894418 0,09176411 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04894418 0,09167085 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04894418 0,09157778 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04894418 0,09148491 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04894418 0,09139222 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04894418 0,09129971 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04894418 0,0912074 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04894418 0,09111527 ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04894418 0,09102333 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04894418 0,09093157 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04894418 0,09084 ! developmental induction GO:0031128 8 8 0,000 0,04894418 0,09074861 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04894418 0,09065741 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04894418 0,09056638 ! actin filament polymerization GO:0030041 9 8 0,000 0,04894418 0,09047554 ! peptide hormone processing GO:0016486 8 8 0,000 0,04894418 0,09038489 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04894418 0,09029441 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04894418 0,09020412 ! regulation of protein localization GO:0032880 58 57 1,000 0,04904055 0,09029143 ! innate immune response GO:0045087 58 58 1,000 0,05059466 0,09305984 ! regulation of cell development GO:0060284 60 59 1,000 0,05216654 0,09585536 ! sterol metabolic process GO:0016125 59 59 1,000 0,05216654 0,09575989 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,05216654 0,09566461 ! protein localization in organelle GO:0033365 59 59 1,000 0,05216654 0,09556951 ! protein polymerization GO:0051258 65 60 1,000 0,05375591 0,09838345 ! lactation GO:0007595 10 9 0,000 0,0548952 0,10036889 ! embryonic pattern specification GO:0009880 10 9 0,000 0,0548952 0,10026942 ! positive regulation of cell size GO:0045793 9 9 0,000 0,0548952 0,10017014 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,0548952 0,10007106 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,0548952 0,09997218 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,0548952 0,09987349 ! viral genome replication GO:0019079 9 9 0,000 0,0548952 0,099775 ! copper ion transport GO:0006825 9 9 0,000 0,0548952 0,0996767 ! lipid phosphorylation GO:0046834 9 9 0,000 0,0548952 0,09957859 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,0548952 0,09948067 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,0548952 0,09938295 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,0548952 0,09928542 ! RNA polyadenylation GO:0043631 9 9 0,000 0,0548952 0,09918808 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,0548952 0,09909094 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,0548952 0,09899398 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,0548952 0,09889721 ! phospholipid efflux GO:0033700 9 9 0,000 0,0548952 0,09880063 ! response to alkaloid GO:0043279 10 9 0,000 0,0548952 0,09870424 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,0548952 0,09860804 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,0548952 0,09851202 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,0548952 0,09841619 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,0548952 0,09832055 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,0548952 0,09822509 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,0548952 0,09812982 ! methionine metabolic process GO:0006555 9 9 0,000 0,0548952 0,09803473 ! glutamine metabolic process GO:0006541 9 9 0,000 0,0548952 0,09793983 ! cerebral cortex development GO:0021987 9 9 0,000 0,0548952 0,09784511 ! response to osmotic stress GO:0006970 9 9 0,000 0,0548952 0,09775058 ! pigmentation during development GO:0048066 9 9 0,000 0,0548952 0,09765622 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,0548952 0,09756205 ! central nervous system neuron development GO:0021954 10 9 0,000 0,0548952 0,09746806 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,0548952 0,09737425 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,0548952 0,09728062 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,0548952 0,09718717 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,0548952 0,0970939 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,0548952 0,09700081 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,0548952 0,0969079 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,0548952 0,09681516 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,0548952 0,09672261 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,0548952 0,09663022 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,0548952 0,09653802 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,0548952 0,09644599 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,0548952 0,09635414 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,0548952 0,09626246 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,0548952 0,09617096 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,0548952 0,09607963 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,0548952 0,09598847 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,0548952 0,09589748 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,0548952 0,09580667 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,0548952 0,09571603 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,0548952 0,09562556 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,0548952 0,09553526 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,0548952 0,09544514 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,0548952 0,09535518 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,0548952 0,09526539 ! collagen catabolic process GO:0030574 9 9 0,000 0,0548952 0,09517577 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,0548952 0,09508632 ! purine base metabolic process GO:0006144 9 9 0,000 0,0548952 0,09499704 ! gas transport GO:0015669 9 9 0,000 0,0548952 0,09490792 ! cholesterol efflux GO:0033344 9 9 0,000 0,0548952 0,09481897 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,0548952 0,09473019 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,0548952 0,09464158 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,0548952 0,09455313 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,0548952 0,09446484 ! defense response to virus GO:0051607 9 9 0,000 0,0548952 0,09437672 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,0548952 0,09428877 ! actin filament-based movement GO:0030048 9 9 0,000 0,0548952 0,09420097 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,0548952 0,09411334 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,05536249 0,09482628 ! carboxylic acid catabolic process GO:0046395 63 61 1,000 0,05536249 0,09473823 GO:0016054|organic acid catabolic process, ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,05698604 0,09742604 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,05698604 0,09733575 ! protein import GO:0017038 62 62 1,000 0,05698604 0,09724562 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,05698604 0,09715566 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,05698604 0,09706587 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,05862628 0,09976752 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,06028294 0,10249213 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,06028294 0,10239766 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06080984 0,10319754 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06080984 0,1031026 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06080984 0,10300784 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06080984 0,10291325 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06080984 0,10281884 ! neuron maturation GO:0042551 10 10 0,000 0,06080984 0,10272459 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06080984 0,10263052 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06080984 0,10253662 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06080984 0,1024429 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06080984 0,10234934 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,06080984 0,10225596 ! hormone secretion GO:0046879 10 10 0,000 0,06080984 0,10216274 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06080984 0,1020697 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06080984 0,10197683 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,06080984 0,10188412 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06080984 0,10179158 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06080984 0,10169921 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06080984 0,10160701 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06080984 0,10151497 ! glial cell development GO:0021782 10 10 0,000 0,06080984 0,10142311 ! phototransduction GO:0007602 11 10 0,000 0,06080984 0,1013314 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,06080984 0,10123987 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06080984 0,10114849 ! myoblast differentiation GO:0045445 10 10 0,000 0,06080984 0,10105729 ! centrosome cycle GO:0007098 10 10 0,000 0,06080984 0,10096624 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06080984 0,10087537 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06080984 0,10078465 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06080984 0,1006941 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06080984 0,10060371 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,06080984 0,10051348 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,06080984 0,10042341 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06080984 0,10033351 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06080984 0,10024377 ! plasma membrane organization GO:0007009 10 10 0,000 0,06080984 0,10015418 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06080984 0,10006476 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,06080984 0,0999755 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06080984 0,09988639 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06080984 0,09979745 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06080984 0,09970866 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06080984 0,09962003 ! exocrine system development GO:0035272 10 10 0,000 0,06080984 0,09953156 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,06080984 0,09944324 ! regulation of protein binding GO:0043393 11 10 0,000 0,06080984 0,09935508 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06080984 0,09926708 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06080984 0,09917923 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06080984 0,09909154 ! protein export from nucleus GO:0006611 10 10 0,000 0,06080984 0,099004 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06080984 0,09891662 ! cytolysis GO:0019835 10 10 0,000 0,06080984 0,09882939 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06080984 0,09874232 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06080984 0,0986554 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06080984 0,09856863 ! histone deacetylation GO:0016575 10 10 0,000 0,06080984 0,09848201 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06080984 0,09839555 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06080984 0,09830924 ! gland morphogenesis GO:0022612 10 10 0,000 0,06080984 0,09822308 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06080984 0,09813707 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06080984 0,09805121 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06080984 0,0979655 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06080984 0,09787994 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06080984 0,09779453 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06080984 0,09770927 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06080984 0,09762416 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06080984 0,09753919 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06080984 0,09745437 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06080984 0,09736971 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06080984 0,09728518 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,06080984 0,09720081 ! nerve development GO:0021675 10 10 0,000 0,06080984 0,09711658 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,06080984 0,09703249 ! gut development GO:0048565 10 10 0,000 0,06080984 0,09694856 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06080984 0,09686476 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06080984 0,09678111 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06080984 0,09669761 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,06080984 0,09661425 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,06534896 0,10373656 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,06534896 0,10364728 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,06534896 0,10355816 ! protein secretion GO:0009306 11 11 0,000 0,06668832 0,10558984 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06668832 0,10549921 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,06668832 0,10540873 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06668832 0,1053184 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,06668832 0,10522823 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06668832 0,10513822 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,06668832 0,10504835 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,06668832 0,10495865 ! skin development GO:0043588 11 11 0,000 0,06668832 0,10486909 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06668832 0,10477969 ! peroxisomal transport GO:0043574 11 11 0,000 0,06668832 0,10469044 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06668832 0,10460134 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,06668832 0,10451239 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,06668832 0,1044236 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,06668832 0,10433495 ! T cell proliferation GO:0042098 11 11 0,000 0,06668832 0,10424646 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,06668832 0,10415811 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,06668832 0,10406992 ! spinal cord development GO:0021510 11 11 0,000 0,06668832 0,10398187 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,06668832 0,10389398 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06668832 0,10380623 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,06668832 0,10371863 ! digestive system process GO:0022600 11 11 0,000 0,06668832 0,10363118 ! fucose metabolic process GO:0006004 11 11 0,000 0,06668832 0,10354387 ! membrane budding GO:0006900 11 11 0,000 0,06668832 0,10345671 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,06668832 0,1033697 ! monoamine transport GO:0015844 11 11 0,000 0,06668832 0,10328284 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06668832 0,10319612 ! body fluid secretion GO:0007589 11 11 0,000 0,06668832 0,10310954 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,06668832 0,10302311 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06668832 0,10293683 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,06668832 0,10285069 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06668832 0,10276469 ! oogenesis GO:0048477 11 11 0,000 0,06668832 0,10267884 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,06668832 0,10259313 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06668832 0,10250757 ! vitamin transport GO:0051180 11 11 0,000 0,06668832 0,10242215 ! hindbrain development GO:0030902 11 11 0,000 0,06668832 0,10233687 ! steroid catabolic process GO:0006706 11 11 0,000 0,06668832 0,10225173 ! endocrine process GO:0050886 11 11 0,000 0,06668832 0,10216673 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,06668832 0,10208187 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,06668832 0,10199716 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,06668832 0,10191258 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06668832 0,10182815 ! regionalization GO:0003002 70 69 1,000 0,06880379 0,10497135 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,06880379 0,10488453 ! regulation of translation GO:0006417 69 69 1,000 0,06880379 0,10479784 ! cell part morphogenesis GO:0032990 75 70 1,000 0,07055371 0,10737447 ! regulation of cell activation GO:0050865 71 71 1,000 0,07231829 0,10996915 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,07253086 0,11020146 ! translational initiation GO:0006413 12 12 0,000 0,07253086 0,11011069 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,07253086 0,11002006 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,07253086 0,10992958 ! initiation of viral infection GO:0019059 12 12 0,000 0,07253086 0,10983926 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,07253086 0,10974908 ! iron ion transport GO:0006826 13 12 0,000 0,07253086 0,10965904 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,07253086 0,10956916 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,07253086 0,10947942 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,07253086 0,10938983 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,07253086 0,10930039 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,07253086 0,10921109 ! collagen metabolic process GO:0032963 12 12 0,000 0,07253086 0,10912194 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,07253086 0,10903293 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,07253086 0,10894407 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,07253086 0,10885535 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,07253086 0,10876678 ! actomyosin structure organization GO:0031032 12 12 0,000 0,07253086 0,10867835 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,07253086 0,10859007 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,07253086 0,10850193 ! retinoid metabolic process GO:0001523 12 12 0,000 0,07253086 0,10841393 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,07253086 0,10832607 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,07253086 0,10823836 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,07253086 0,10815079 GO:0006505|GPI anchor metabolic process, ! acute-phase response GO:0006953 12 12 0,000 0,07253086 0,10806336 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,07253086 0,10797607 ! vacuolar transport GO:0007034 12 12 0,000 0,07253086 0,10788892 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,07253086 0,10780192 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,07253086 0,10771505 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,07253086 0,10762832 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,07253086 0,10754173 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,07253086 0,10745529 ! male gonad development GO:0008584 12 12 0,000 0,07253086 0,10736898 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,07253086 0,1072828 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,07253086 0,10719677 ! renal system process GO:0003014 12 12 0,000 0,07253086 0,10711088 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,07253086 0,10702512 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,07253086 0,1069395 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,07253086 0,10685402 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,07253086 0,10676867 ! pallium development GO:0021543 13 12 0,000 0,07253086 0,10668346 ! cell fate determination GO:0001709 12 12 0,000 0,07253086 0,10659838 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,07253086 0,10651345 ! G1 phase GO:0051318 13 12 0,000 0,07253086 0,10642864 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,07253086 0,10634397 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,07253086 0,10625944 ! detection of light stimulus GO:0009583 13 12 0,000 0,07253086 0,10617504 ! synaptogenesis GO:0007416 12 12 0,000 0,07253086 0,10609077 ! hormone transport GO:0009914 12 12 0,000 0,07253086 0,10600664 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,07253086 0,10592264 ! heme biosynthetic process GO:0006783 12 12 0,000 0,07253086 0,10583878 ! spermatid differentiation GO:0048515 13 12 0,000 0,07253086 0,10575504 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,07253086 0,10567144 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,07253086 0,10558797 ! neural tube closure GO:0001843 13 12 0,000 0,07253086 0,10550464 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,07253086 0,10542143 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,07833767 0,11377173 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,07833767 0,11368215 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,07833767 0,1135927 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,07833767 0,1135034 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,07833767 0,11341424 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,07833767 0,11332522 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,07833767 0,11323633 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,07833767 0,11314759 ! regeneration GO:0031099 13 13 0,000 0,07833767 0,11305899 ! keratinization GO:0031424 13 13 0,000 0,07833767 0,11297052 ! post-embryonic development GO:0009791 14 13 0,000 0,07833767 0,11288219 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,07833767 0,112794 ! patterning of blood vessels GO:0001569 13 13 0,000 0,07833767 0,11270595 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,07833767 0,11261804 ! regulation of innate immune response GO:0045088 13 13 0,000 0,07833767 0,11253026 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,07833767 0,11244262 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,07833767 0,11235512 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,07833767 0,11226775 ! autophagy GO:0006914 13 13 0,000 0,07833767 0,11218052 ! ureteric bud development GO:0001657 13 13 0,000 0,07833767 0,11209342 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,07833767 0,11200646 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,07833767 0,11191963 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,07833767 0,11183294 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,07833767 0,11174638 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,07833767 0,11165996 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,07833767 0,11157367 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,07833767 0,11148751 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,07833767 0,11140149 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,07833767 0,11131559 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,07833767 0,11122984 ! vasodilation GO:0042311 14 13 0,000 0,07833767 0,11114421 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,07833767 0,11105871 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,07833767 0,11097335 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,07833767 0,11088812 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,07833767 0,11080301 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,07833767 0,11071804 ! immunoglobulin production GO:0002377 13 13 0,000 0,07833767 0,1106332 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,07833767 0,11054849 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,07833767 0,11046391 ! cell-cell junction organization GO:0045216 13 13 0,000 0,07833767 0,11037945 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,07833767 0,11029513 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,07833767 0,11021094 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,07833767 0,11012687 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,07833767 0,11004293 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,07833767 0,10995912 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,07833767 0,10987544 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,07833767 0,10979188 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,07833767 0,10970845 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,07833767 0,10962515 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,07833767 0,10954198 ! telomere organization GO:0032200 13 13 0,000 0,07833767 0,10945893 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,07833767 0,109376 ! regulation of amine transport GO:0051952 13 13 0,000 0,07833767 0,10929321 ! tissue homeostasis GO:0001894 13 13 0,000 0,07833767 0,10921053 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,07833767 0,10912799 ! response to oxidative stress GO:0006979 76 75 1,000 0,07951857 0,11068937 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,08135294 0,11315734 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,08320057 0,11564001 ! neuron fate commitment GO:0048663 14 14 0,000 0,08410896 0,11681449 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,08410896 0,11672652 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,08410896 0,11663869 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,08410896 0,11655099 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,08410896 0,11646343 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,08410896 0,11637599 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,08410896 0,11628869 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,08410896 0,11620152 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,08410896 0,11611447 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,08410896 0,11602756 ! vesicle docking GO:0048278 14 14 0,000 0,08410896 0,11594078 ! superoxide metabolic process GO:0006801 15 14 0,000 0,08410896 0,11585413 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,08410896 0,1157676 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,08410896 0,11568121 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,08410896 0,11559495 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,08410896 0,11550881 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,08410896 0,1154228 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,08410896 0,11533692 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,08410896 0,11525117 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,08410896 0,11516554 ! lysosome organization GO:0007040 14 14 0,000 0,08410896 0,11508005 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,08410896 0,11499468 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,08410896 0,11490943 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,08410896 0,11482431 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,08410896 0,11473932 ! primary neural tube formation GO:0014020 15 14 0,000 0,08410896 0,11465445 ! peptide cross-linking GO:0018149 14 14 0,000 0,08410896 0,11456971 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,08410896 0,1144851 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,08410896 0,11440061 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,08410896 0,11431624 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,08410896 0,114232 ! formation of primary germ layer GO:0001704 14 14 0,000 0,08410896 0,11414788 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,08410896 0,11406389 ! collagen fibril organization GO:0030199 14 14 0,000 0,08410896 0,11398002 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,08410896 0,11389627 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,08410896 0,11381264 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,08410896 0,11372914 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,08410896 0,11364576 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,08410896 0,11356251 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,08410896 0,11347937 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,08410896 0,11339636 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,08410896 0,11331347 ! regulation of protein modification process GO:0031399 79 78 1,000 0,08506123 0,11451267 ! neuron projection development GO:0031175 85 80 1,000 0,08882073 0,11948658 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,08984496 0,12077626 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,08984496 0,12068823 ! positive regulation of ossification GO:0045778 15 15 0,000 0,08984496 0,12060033 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,08984496 0,12051256 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,08984496 0,12042491 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,08984496 0,12033739 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,08984496 0,12025 ! response to vitamin GO:0033273 15 15 0,000 0,08984496 0,12016274 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,08984496 0,1200756 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,08984496 0,11998859 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,08984496 0,1199017 ! ovarian follicle development GO:0001541 15 15 0,000 0,08984496 0,11981494 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,08984496 0,11972831 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,08984496 0,1196418 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,08984496 0,11955542 ! heme metabolic process GO:0042168 15 15 0,000 0,08984496 0,11946916 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,08984496 0,11938302 ! chromosome condensation GO:0030261 15 15 0,000 0,08984496 0,11929701 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,08984496 0,11921113 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,08984496 0,11912536 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,08984496 0,11903972 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,08984496 0,11895421 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,08984496 0,11886881 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,08984496 0,11878354 ! phospholipid transport GO:0015914 15 15 0,000 0,08984496 0,11869839 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,08984496 0,11861336 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,08984496 0,11852846 ! glutathione metabolic process GO:0006749 16 15 0,000 0,08984496 0,11844367 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,08984496 0,11835901 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,08984496 0,11827447 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,08984496 0,11819005 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,08984496 0,11810574 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,08984496 0,11802156 ! protein homooligomerization GO:0051260 15 15 0,000 0,08984496 0,1179375 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,08984496 0,11785356 ! MAPKKK cascade GO:0000165 82 81 1,000 0,09071913 0,11891562 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,09554585 0,12515352 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,09554585 0,12506464 ! circadian rhythm GO:0007623 16 16 0,000 0,09554585 0,12497588 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,09554585 0,12488724 ! vacuole organization GO:0007033 16 16 0,000 0,09554585 0,12479873 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,09554585 0,12471035 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,09554585 0,12462209 ! vesicle targeting GO:0006903 17 16 0,000 0,09554585 0,12453395 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,09554585 0,12444594 ! iron ion homeostasis GO:0055072 16 16 0,000 0,09554585 0,12435806 ! positive regulation of cell development GO:0010720 16 16 0,000 0,09554585 0,1242703 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,09554585 0,12418266 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,09554585 0,12409514 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,09554585 0,12400775 ! cell fate specification GO:0001708 16 16 0,000 0,09554585 0,12392049 ! pentose metabolic process GO:0019321 16 16 0,000 0,09554585 0,12383334 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,09554585 0,12374632 ! cofactor catabolic process GO:0051187 16 16 0,000 0,09554585 0,12365942 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,09554585 0,12357264 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,09554585 0,12348598 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,09554585 0,12339945 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,09554585 0,12331303 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,09554585 0,12322674 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,09554585 0,12314057 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,09554585 0,12305451 ! regulation of coagulation GO:0050818 17 16 0,000 0,09554585 0,12296858 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,0964863 0,12409229 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,09843196 0,12650635 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,09843196 0,12641819 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,1003889 0,12884175 GO:0006644|phospholipid metabolic process, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,10121187 0,12980757 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,10121187 0,1297173 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,10121187 0,12962715 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,10121187 0,12953714 ! leukocyte adhesion GO:0007159 17 17 0,000 0,10121187 0,12944724 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,10121187 0,12935747 ! sensory perception of smell GO:0007608 17 17 0,000 0,10121187 0,12926783 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,10121187 0,12917831 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,10121187 0,12908891 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,10121187 0,12899964 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,10121187 0,12891049 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,10121187 0,12882146 ! neural crest cell development GO:0014032 19 17 0,000 0,10121187 0,12873256 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,10121187 0,12864378 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,10121187 0,12855512 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,10121187 0,12846658 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,10121187 0,12837817 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,10121187 0,12828987 ! pigmentation GO:0043473 17 17 0,000 0,10121187 0,1282017 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,10121187 0,12811365 ! adult locomotory behavior GO:0008344 17 17 0,000 0,10121187 0,12802572 ! embryonic organ development GO:0048568 17 17 0,000 0,10121187 0,12793791 ! liver development GO:0001889 17 17 0,000 0,10121187 0,12785022 ! gene silencing GO:0016458 17 17 0,000 0,10121187 0,12776265 ! male gamete generation GO:0048232 90 88 1,000 0,10433581 0,13161594 GO:0007283|spermatogenesis, ! chemotaxis GO:0006935 90 89 1,000 0,10632536 0,13403395 GO:0042330|taxis, ! mRNA export from nucleus GO:0006406 18 18 0,000 0,10684321 0,13459469 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,10684321 0,13450276 ! membrane docking GO:0022406 18 18 0,000 0,10684321 0,13441095 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,10684321 0,13431926 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,10684321 0,1342277 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,10684321 0,13413626 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,10684321 0,13404495 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,10684321 0,13395377 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,10684321 0,1338627 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,10684321 0,13377176 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,10684321 0,13368095 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,10684321 0,13359025 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,10684321 0,13349969 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,10684321 0,13340924 ! BMP signaling pathway GO:0030509 18 18 0,000 0,10684321 0,13331891 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,10684321 0,13322871 ! DNA replication GO:0006260 91 91 1,000 0,11033564 0,13749059 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,11235597 0,13991354 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,11235597 0,13981907 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,11244008 0,13982933 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,11244008 0,13973505 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,11244008 0,13964088 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,11244008 0,13954685 ! feeding behavior GO:0007631 19 19 0,000 0,11244008 0,13945294 ! peroxisome organization GO:0007031 19 19 0,000 0,11244008 0,13935916 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,11244008 0,13926551 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,11244008 0,13917198 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,11244008 0,13907857 ! metanephros development GO:0001656 19 19 0,000 0,11244008 0,13898529 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,11244008 0,13889214 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,11244008 0,13879911 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,11244008 0,13870621 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,11244008 0,13861343 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,11244008 0,13852077 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,11244008 0,13842824 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,11244008 0,13833583 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,11244008 0,13824354 ! eye morphogenesis GO:0048592 19 19 0,000 0,11244008 0,13815138 ! vesicle localization GO:0051648 20 19 0,000 0,11244008 0,13805934 ! tissue morphogenesis GO:0048729 94 93 1,000 0,11438616 0,14035532 ! pattern specification process GO:0007389 96 94 1,000 0,11642602 0,14276325 ! epidermis development GO:0008544 94 94 1,000 0,11642602 0,14266833 ! regulation of muscle development GO:0048634 21 20 0,000 0,11800269 0,1445043 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,11800269 0,14440834 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,11800269 0,14431252 ! organic ether metabolic process GO:0018904 20 20 0,000 0,11800269 0,14421682 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,11800269 0,14412125 ! nucleus organization GO:0006997 20 20 0,000 0,11800269 0,1440258 ! phagocytosis GO:0006909 21 20 0,000 0,11800269 0,14393049 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,11800269 0,14383529 ! protein targeting to membrane GO:0006612 22 20 0,000 0,11800269 0,14374023 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,11800269 0,14364529 ! chromatin remodeling GO:0006338 20 20 0,000 0,11800269 0,14355047 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,11800269 0,14345578 ! female gamete generation GO:0007292 20 20 0,000 0,11800269 0,14336122 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,11800269 0,14326678 ! RNA modification GO:0009451 20 20 0,000 0,11800269 0,14317246 ! single fertilization GO:0007338 21 20 0,000 0,11800269 0,14307827 ! regulation of B cell activation GO:0050864 20 20 0,000 0,11800269 0,1429842 ! regulation of cell growth GO:0001558 97 96 1,000 0,12053399 0,14595542 ! mRNA catabolic process GO:0006402 21 21 0,000 0,12353125 0,1494866 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,12353125 0,14938851 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,12353125 0,14929055 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,12353125 0,14919272 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,12353125 0,14909502 ! ear morphogenesis GO:0042471 21 21 0,000 0,12353125 0,14899744 ! organic anion transport GO:0015711 21 21 0,000 0,12353125 0,14889999 ! cholesterol transport GO:0030301 21 21 0,000 0,12353125 0,14880267 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,12353125 0,14870548 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,12353125 0,14860841 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,12353125 0,14851148 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,12353125 0,14841466 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,12353125 0,14831797 ! regulation of proteolysis GO:0030162 21 21 0,000 0,12353125 0,14822141 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,12353125 0,14812498 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,12467835 0,14940325 ! anti-apoptosis GO:0006916 100 99 1,000 0,12676371 0,15180346 ! ectoderm development GO:0007398 99 99 1,000 0,12676371 0,15170488 ! response to other organism GO:0051707 101 100 1,000 0,12885761 0,15411069 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,12902595 0,15421195 ! odontogenesis GO:0042476 22 22 0,000 0,12902595 0,15411201 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,12902595 0,15401219 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,12902595 0,15391251 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,12902595 0,15381295 ! ovulation cycle process GO:0022602 22 22 0,000 0,12902595 0,15371353 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,12902595 0,15361423 ! cell chemotaxis GO:0060326 23 22 0,000 0,12902595 0,15351506 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,12902595 0,15341602 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,12902595 0,1533171 ! male sex differentiation GO:0046661 22 22 0,000 0,12902595 0,15321832 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,12902595 0,15311966 ! biopolymer methylation GO:0043414 22 22 0,000 0,12902595 0,15302112 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,12902595 0,15292272 ! detection of external stimulus GO:0009581 23 22 0,000 0,12902595 0,15282444 ! neuron migration GO:0001764 22 22 0,000 0,12902595 0,15272628 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,12902595 0,15262826 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,12902595 0,15253036 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,12902595 0,15243258 ! aerobic respiration GO:0009060 22 22 0,000 0,12902595 0,15233493 ! cytokine production GO:0001816 22 22 0,000 0,12902595 0,1522374 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,12902595 0,15214 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,134487 0,15847797 ! viral infectious cycle GO:0019058 23 23 0,000 0,134487 0,1583767 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,134487 0,15827557 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,134487 0,15817456 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,134487 0,15807369 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,134487 0,15797294 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,134487 0,15787232 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,134487 0,15777183 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,134487 0,15767146 ! female gonad development GO:0008585 23 23 0,000 0,134487 0,15757123 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,134487 0,15747112 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,134487 0,15737114 ! gliogenesis GO:0042063 24 24 0,000 0,1399146 0,16361841 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,1399146 0,16351465 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,1399146 0,16341103 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,1399146 0,16330754 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,1399146 0,16320418 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,1399146 0,16310096 ! ovulation cycle GO:0042698 24 24 0,000 0,1399146 0,16299786 ! fertilization GO:0009566 25 24 0,000 0,1399146 0,16289489 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,1399146 0,16279205 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,1399146 0,16268934 ! glucan metabolic process GO:0044042 25 24 0,000 0,1399146 0,16258677 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,14530895 0,16874883 ! negative regulation of secretion GO:0051048 26 25 0,000 0,14530895 0,16864257 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,14530895 0,16853644 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,14530895 0,16843044 ! cellular component disassembly GO:0022411 26 25 0,000 0,14530895 0,16832458 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,14530895 0,16821884 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,14530895 0,16811325 ! excretion GO:0007588 25 25 0,000 0,14530895 0,16800778 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,14530895 0,16790244 ! gastrulation GO:0007369 25 25 0,000 0,14530895 0,16779724 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,14530895 0,16769217 ! regulation of endocytosis GO:0030100 25 25 0,000 0,14530895 0,16758723 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,14530895 0,16748243 ! positive regulation of defense response GO:0031349 26 26 0,000 0,15067025 0,1735533 ! glycolysis GO:0006096 26 26 0,000 0,15067025 0,17344489 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,15067025 0,17333663 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,15067025 0,17322849 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,15067025 0,1731205 ! cellular defense response GO:0006968 26 26 0,000 0,15067025 0,17301263 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,15067025 0,1729049 ! regulation of protein secretion GO:0050708 26 26 0,000 0,15067025 0,17279731 ! germ cell development GO:0007281 27 26 0,000 0,15067025 0,17268985 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,15067025 0,17258252 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,15067025 0,17247533 ! chloride transport GO:0006821 27 27 0,000 0,1559987 0,17846406 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,1559987 0,17835335 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,1559987 0,17824278 ! peptide metabolic process GO:0006518 29 27 0,000 0,1559987 0,17813235 ! mesenchymal cell development GO:0014031 29 27 0,000 0,1559987 0,17802205 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,1559987 0,17791188 ! defense response to bacterium GO:0042742 27 27 0,000 0,1559987 0,17780186 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,1559987 0,17769197 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,16129449 0,18361072 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,16129449 0,18349738 GO:0007254|JNK cascade, ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,16129449 0,18338418 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,16129449 0,18327111 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,16129449 0,18315819 ! cartilage development GO:0051216 29 28 0,000 0,16129449 0,18304541 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,16655782 0,18890219 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,16655782 0,18878602 ! leukocyte migration GO:0050900 30 29 0,000 0,16655782 0,18866998 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,16655782 0,18855409 ! antigen processing and presentation GO:0019882 29 29 0,000 0,16655782 0,18843835 ! tRNA processing GO:0008033 29 29 0,000 0,16655782 0,18832274 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,16655782 0,18820727 ! adult behavior GO:0030534 30 29 0,000 0,16655782 0,18809195 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,16655782 0,18797677 ! transition metal ion transport GO:0000041 31 30 0,000 0,17178888 0,19376188 ! RNA catabolic process GO:0006401 30 30 0,000 0,17178888 0,19364337 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,17178888 0,19352501 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,17178888 0,19340679 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,17178888 0,19328871 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,17178888 0,19317078 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,17178888 0,193053 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,17178888 0,19293535 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,17178888 0,19281785 ! regulation of ossification GO:0030278 30 30 0,000 0,17178888 0,1927005 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,17178888 0,19258328 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,17178888 0,19246621 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,17178888 0,19234928 ! vesicle organization GO:0016050 30 30 0,000 0,17178888 0,19223249 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,17178888 0,19211585 ! membrane fusion GO:0006944 31 31 0,000 0,17698787 0,19780998 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,17698787 0,19769009 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,17698787 0,19757035 ! ion transmembrane transport GO:0034220 31 31 0,000 0,17698787 0,19745076 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,17698787 0,19733131 ! digestion GO:0007586 31 31 0,000 0,17698787 0,197212 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,17698787 0,19709284 ! regulation of heart contraction GO:0008016 31 31 0,000 0,17698787 0,19697382 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,17698787 0,19685495 ! camera-type eye development GO:0043010 31 31 0,000 0,17698787 0,19673622 ! extracellular matrix organization GO:0030198 31 31 0,000 0,17698787 0,19661763 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,17698787 0,19649919 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,17698787 0,19638089 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,17698787 0,19626273 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,17698787 0,19614471 ! cell redox homeostasis GO:0045454 32 32 0,000 0,18215498 0,20174978 ! glucose catabolic process GO:0006007 32 32 0,000 0,18215498 0,20162861 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,18215498 0,20150758 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,18215498 0,2013867 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,18215498 0,20126597 ! kidney development GO:0001822 32 32 0,000 0,18215498 0,20114538 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,1872904 0,20669234 ! amino acid transport GO:0006865 33 33 0,000 0,1872904 0,20656864 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,1872904 0,2064451 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,1872904 0,2063217 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,1872904 0,20619845 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,1872904 0,20607535 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,1872904 0,20595239 ! regulation of actin filament length GO:0030832 34 34 0,000 0,19239431 0,21143871 ! response to metal ion GO:0010038 34 34 0,000 0,19239431 0,21131271 ! ear development GO:0043583 34 34 0,000 0,19239431 0,21118685 ! muscle cell differentiation GO:0042692 35 34 0,000 0,19239431 0,21106114 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,19239431 0,21093559 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,19239431 0,21081018 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,19239431 0,21068492 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,19239431 0,21055981 ! secondary metabolic process GO:0019748 34 34 0,000 0,19239431 0,21043485 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,19239431 0,21031004 ! detection of stimulus GO:0051606 36 34 0,000 0,19239431 0,21018537 ! acute inflammatory response GO:0002526 35 35 0,000 0,19746692 0,21559925 ! regulation of cellular component size GO:0032535 35 35 0,000 0,19746692 0,2154716 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,19746692 0,2153441 ! mesoderm development GO:0007498 35 35 0,000 0,19746692 0,21521675 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,19746692 0,21508956 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,19746692 0,21496251 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,19746692 0,21483561 ! regulation of immune effector process GO:0002697 35 35 0,000 0,19746692 0,21470887 ! hydrogen transport GO:0006818 36 36 0,000 0,2025084 0,22006072 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,2025084 0,21993104 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,2025084 0,21980152 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,2025084 0,21967215 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,2025084 0,21954293 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,2025084 0,21941386 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,2025084 0,21928495 ! gonad development GO:0008406 36 36 0,000 0,2025084 0,21915618 ! activation of immune response GO:0002253 36 36 0,000 0,2025084 0,21902757 ! coagulation GO:0050817 39 36 0,000 0,2025084 0,21889911 GO:0007596|blood coagulation, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,20751894 0,22418371 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,20751894 0,22405237 ! eye development GO:0001654 37 37 0,000 0,20751894 0,2239212 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,20751894 0,22379017 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,20751894 0,2236593 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,20751894 0,22352858 ! positive regulation of secretion GO:0051047 39 38 0,000 0,21249873 0,22875885 ! neurotransmitter transport GO:0006836 40 38 0,000 0,21249873 0,22862531 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,21249873 0,22849192 ! exocytosis GO:0006887 40 38 0,000 0,21249873 0,22835869 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,21249873 0,22822561 ! hexose catabolic process GO:0019320 38 38 0,000 0,21249873 0,22809269 ! RNA elongation GO:0006354 38 38 0,000 0,21249873 0,22795992 ! hemostasis GO:0007599 42 39 0,000 0,21744794 0,23313354 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,21744794 0,232998 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,21744794 0,23286262 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,21744794 0,23272739 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,21744794 0,23259232 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,21744794 0,2324574 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,21744794 0,23232264 ! limb development GO:0060173 39 39 0,000 0,21744794 0,23218804 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,22236678 0,23730282 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,22236678 0,23716549 ! amine catabolic process GO:0009310 42 41 0,000 0,22725541 0,24223928 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,22725541 0,24209926 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,22725541 0,2419594 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,22725541 0,2418197 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,22725541 0,24168016 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,22725541 0,24154078 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,23211401 0,24656261 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,23211401 0,24642058 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,23211401 0,24627872 ! protein ubiquitination GO:0016567 43 42 0,000 0,23211401 0,24613701 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,23211401 0,24599547 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,23211401 0,2458541 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,23211401 0,24571288 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,23211401 0,24557183 ! alcohol catabolic process GO:0046164 43 43 0,000 0,23694278 0,25053674 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,23694278 0,25039309 ! humoral immune response GO:0006959 44 44 0,000 0,24174188 0,25531822 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,24174188 0,25517199 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,24174188 0,25502592 ! amine biosynthetic process GO:0009309 46 45 0,000 0,2465115 0,25990886 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,2465115 0,25976026 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,2465115 0,25961182 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,2465115 0,25946356 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,2465115 0,25931546 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,25125181 0,26415122 ! tube morphogenesis GO:0035239 47 46 0,000 0,25125181 0,26400062 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,25125181 0,26385019 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,25125181 0,26369993 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,25125181 0,26354985 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,25596298 0,26833889 ! amine transport GO:0015837 47 47 0,000 0,25596298 0,26818634 ! rhythmic process GO:0048511 47 47 0,000 0,25596298 0,26803396 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,2606452 0,272782 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,2606452 0,27262719 ! DNA recombination GO:0006310 48 48 0,000 0,2606452 0,27247255 ! regulation of ligase activity GO:0051340 50 49 0,000 0,26529863 0,27717992 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,26529863 0,27702288 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,26529863 0,27686601 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,26992345 0,28153307 ! chromatin assembly GO:0031497 50 50 0,000 0,26992345 0,28137383 GO:0006334|nucleosome assembly, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,26992345 0,28121477 ! transcription initiation GO:0006352 50 50 0,000 0,26992345 0,28105589 ! positive regulation of immune response GO:0050778 51 51 0,000 0,27451984 0,28568044 ! rRNA metabolic process GO:0016072 51 51 0,000 0,27451984 0,28551922 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,27451984 0,28535818 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,27451984 0,28519733 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,27908795 0,28977977 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,27908795 0,28961661 ! sodium ion transport GO:0006814 53 53 0,000 0,28362797 0,29416226 ! tRNA metabolic process GO:0006399 53 53 0,000 0,28362797 0,29399682 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,28362797 0,29383156 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,28814005 0,29833826 ! response to virus GO:0009615 54 54 0,000 0,28814005 0,29817075 ! hormone metabolic process GO:0042445 55 54 0,000 0,28814005 0,29800343 ! sulfur metabolic process GO:0006790 55 54 0,000 0,28814005 0,29783629 ! nucleosome organization GO:0034728 55 55 0,000 0,29262437 0,30230197 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,29262437 0,30213261 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,2970811 0,30656241 ! ATP metabolic process GO:0046034 57 57 0,000 0,30151039 0,31095895 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,30151039 0,31078504 ! dephosphorylation GO:0016311 60 59 0,000 0,31028735 0,31965321 ! immune effector process GO:0002252 59 59 0,000 0,31028735 0,31947463 ! potassium ion transport GO:0006813 60 60 0,000 0,31463534 0,32377048 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,31463534 0,32358981 ! cellular respiration GO:0045333 62 61 0,000 0,31895656 0,32785105 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,31895656 0,3276683 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,31895656 0,32748576 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,32325115 0,3317104 ! regulation of secretion GO:0051046 65 63 0,000 0,3275193 0,33590321 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,3275193 0,33571639 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,3275193 0,33552978 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,33176114 0,33968655 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,33176114 0,33949794 ! anion transport GO:0006820 65 65 0,000 0,33597685 0,34362117 ! regulation of hormone levels GO:0010817 66 65 0,000 0,33597685 0,34343058 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,34016658 0,34752051 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,34016658 0,34732798 ! DNA packaging GO:0006323 66 66 0,000 0,34016658 0,34713566 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,34016658 0,34694356 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,34433048 0,35099617 ! muscle contraction GO:0006936 67 67 0,000 0,34433048 0,35080215 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,34846872 0,35482202 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,34846872 0,35462609 ! sensory perception of sound GO:0007605 71 69 0,000 0,35258144 0,35861346 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,3566688 0,36257065 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,36073095 0,36649787 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,36073095 0,36629594 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,36073095 0,36609424 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,36073095 0,36589275 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,36073095 0,36569149 ! secretion by cell GO:0032940 75 72 0,000 0,36476804 0,36958081 ! muscle system process GO:0003012 72 72 0,000 0,36476804 0,36937775 ! sensory organ development GO:0007423 72 72 0,000 0,36476804 0,3691749 ! regulation of cytokine production GO:0001817 72 72 0,000 0,36476804 0,36897228 ! electron transport chain GO:0022900 75 74 0,000 0,37276766 0,37685727 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,37276766 0,37665066 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,37673049 0,38044618 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,37673049 0,38023783 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,38066885 0,38400257 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,38458291 0,38773868 ! metal ion homeostasis GO:0055065 78 78 0,000 0,3884728 0,39144635 ! regulation of immune response GO:0050776 78 78 0,000 0,3884728 0,39123244 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,39618067 0,39877716 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,40756486 0,41001203 ! ncRNA processing GO:0034470 83 83 0,000 0,40756486 0,40978835 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,4260743 0,42816518 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,42970781 0,4315812 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,43331885 0,43497094 ! brain development GO:0007420 91 90 0,000 0,43331885 0,43473416 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,43690755 0,4380961 ! visual perception GO:0007601 93 92 0,000 0,44047406 0,44143213 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,44047406 0,44119222 ! regulation of response to stress GO:0080134 97 94 0,000 0,44754099 0,44802718 ! cofactor metabolic process GO:0051186 95 94 0,000 0,44754099 0,44778395 ! endocytosis GO:0006897 99 98 0,000 0,46141429 0,46141429 GO:0010324|membrane invagination,