pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6634-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 3,361E-09 8,086E-06 ! spindle organization GO:0007051 46 32 5,000 1,368E-08 1,646E-05 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 1,383E-07 1,11E-04 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 3,235E-07 1,946E-04 ! cell killing GO:0001906 29 15 3,000 8,814E-07 4,241E-04 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 2,000 1,327E-06 5,321E-04 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 3,000 3,066E-06 1,054E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 3,066E-06 9,222E-04 ! positive regulation of intracellular transport GO:0032388 37 22 3,000 4,593E-06 1,228E-03 ! regulation of fat cell differentiation GO:0045598 15 8 2,000 7,347E-06 1,768E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 7,347E-06 1,607E-03 ! cell cycle arrest GO:0007050 213 100 5,000 1,349E-05 2,705E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,562E-05 2,892E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 2,843E-05 4,886E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 2,843E-05 4,56E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of caspase activity GO:0043281 122 72 4,000 3,586E-05 5,393E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 3,905E-05 5,526E-03 ! regulation of endopeptidase activity GO:0052548 125 74 4,000 4,095E-05 5,474E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 4,668E-05 5,911E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 4,668E-05 5,616E-03 ! regulation of peptidase activity GO:0052547 134 79 4,000 5,612E-05 6,43E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 2,000 5,813E-05 6,358E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 7,128E-05 7,456E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 8,532E-05 8,553E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 8,623E-05 8,298E-03 ! negative regulation of protein catabolic process GO:0042177 40 17 2,000 8,623E-05 7,979E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 8,623E-05 7,684E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 9,307E-05 7,997E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 9,307E-05 7,721E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 9,307E-05 7,464E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 9,307E-05 7,223E-03 ! activation of caspase activity GO:0006919 84 48 3,000 1,101E-04 8,277E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,101E-04 8,027E-03 ! regulation of action potential GO:0001508 95 49 3,000 1,194E-04 8,449E-03 ! regulation of membrane potential GO:0042391 164 93 4,000 1,221E-04 8,397E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 1,397E-04 9,337E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,429E-04 9,294E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,429E-04 9,049E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 1,49E-04 9,191E-03 ! response to UV GO:0009411 104 53 3,000 1,624E-04 9,768E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 1,661E-04 9,748E-03 ! positive regulation of caspase activity GO:0043280 95 55 3,000 1,876E-04 0,01074944 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 3,000 1,876E-04 0,01049945 ! nuclear export GO:0051168 97 55 3,000 1,876E-04 0,01026083 ! microtubule-based transport GO:0010970 54 22 2,000 1,916E-04 0,01024527 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,916E-04 0,01002255 ! apoptotic nuclear changes GO:0030262 32 22 2,000 1,916E-04 9,809E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 2,013E-04 0,01008895 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 2,156E-04 0,01058662 ! positive regulation of cell migration GO:0030335 126 57 3,000 2,156E-04 0,01037489 ! regulation of intracellular transport GO:0032386 101 57 3,000 2,156E-04 0,01017146 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 2,000 2,195E-04 0,01015759 ! fatty acid transport GO:0015908 44 23 2,000 2,195E-04 9,966E-03 ! negative regulation of catabolic process GO:0009895 50 23 2,000 2,195E-04 9,781E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 2,499E-04 0,01093411 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 2,499E-04 0,01073886 ! protein tetramerization GO:0051262 52 24 2,000 2,499E-04 0,01055046 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,605E-04 0,01080668 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,605E-04 0,01062352 ! Notch receptor processing GO:0007220 8 5 1,000 2,605E-04 0,01044646 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,605E-04 0,01027521 ! lymph vessel development GO:0001945 10 5 1,000 2,605E-04 0,01010948 ! anagen GO:0042640 6 5 1,000 2,605E-04 9,949E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,605E-04 9,794E-03 ! microvillus organization GO:0032528 7 5 1,000 2,605E-04 9,643E-03 GO:0030033|microvillus assembly, ! polyol biosynthetic process GO:0046173 5 5 1,000 2,605E-04 9,497E-03 ! sister chromatid cohesion GO:0007062 12 5 1,000 2,605E-04 9,355E-03 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 2,605E-04 9,217E-03 GO:0051489|regulation of filopodium assembly, ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,605E-04 9,084E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,605E-04 8,954E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 2,605E-04 8,828E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,605E-04 8,705E-03 ! decidualization GO:0046697 11 5 1,000 2,605E-04 8,586E-03 ! lymphocyte activation during immune response GO:0002285 9 5 1,000 2,605E-04 8,47E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,605E-04 8,357E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 2,605E-04 8,247E-03 GO:0051930|regulation of sensory perception of pain, ! receptor biosynthetic process GO:0032800 7 5 1,000 2,605E-04 8,14E-03 ! stem cell division GO:0017145 11 5 1,000 2,605E-04 8,036E-03 GO:0048103|somatic stem cell division, ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 2,63E-04 8,01E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 2,803E-04 8,431E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 2,83E-04 8,405E-03 ! receptor metabolic process GO:0043112 46 25 2,000 2,83E-04 8,303E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 3,187E-04 9,237E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 3,187E-04 9,127E-03 GO:0045936|negative regulation of phosphate metabolic process, ! lymphocyte mediated immunity GO:0002449 114 64 3,000 3,373E-04 9,546E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 3,373E-04 9,435E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 3,571E-04 9,877E-03 ! spliceosomal snRNP biogenesis GO:0000387 36 27 2,000 3,571E-04 9,765E-03 ! response to toxin GO:0009636 47 27 2,000 3,571E-04 9,655E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 3,571E-04 9,548E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 3,571E-04 9,443E-03 ! sleep GO:0030431 13 6 1,000 3,894E-04 0,01018479 ! male meiosis GO:0007140 7 6 1,000 3,894E-04 0,01007528 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 1,000 3,894E-04 9,968E-03 ! male sex determination GO:0030238 15 6 1,000 3,894E-04 9,863E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 3,894E-04 9,76E-03 GO:0051653|spindle localization, ! monocyte differentiation GO:0030224 12 6 1,000 3,894E-04 9,66E-03 ! hair follicle maturation GO:0048820 7 6 1,000 3,894E-04 9,561E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 3,894E-04 9,465E-03 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 3,894E-04 9,37E-03 ! maternal placenta development GO:0001893 12 6 1,000 3,894E-04 9,277E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,894E-04 9,186E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 4,02E-04 9,391E-03 ! chromosome segregation GO:0007059 113 67 3,000 4,02E-04 9,3E-03 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 4,428E-04 0,01014665 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 4,428E-04 0,01005092 ! cell cycle checkpoint GO:0000075 137 69 3,000 4,498E-04 0,01011479 ! negative regulation of cell size GO:0045792 134 69 3,000 4,498E-04 0,01002113 ! ensheathment of neurons GO:0007272 57 30 2,000 4,902E-04 0,01081946 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 4,902E-04 0,0107211 ! regulation of B cell activation GO:0050864 50 30 2,000 4,902E-04 0,01062451 ! iron ion homeostasis GO:0055072 54 31 2,000 5,406E-04 0,01161397 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 5,406E-04 0,01151119 GO:0043433|negative regulation of transcription factor activity, ! regulation of helicase activity GO:0051095 15 7 1,000 5,434E-04 0,01146812 ! prostate gland development GO:0030850 13 7 1,000 5,434E-04 0,01136839 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 5,434E-04 0,01127039 ! mRNA stabilization GO:0048255 18 7 1,000 5,434E-04 0,01117406 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,434E-04 0,01107937 ! lipoprotein transport GO:0042953 14 7 1,000 5,434E-04 0,01098626 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 5,434E-04 0,01089471 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 5,434E-04 0,01080467 ! B cell lineage commitment GO:0002326 21 7 1,000 5,434E-04 0,01071611 ! T cell lineage commitment GO:0002360 16 7 1,000 5,434E-04 0,01062899 ! response to tumor cell GO:0002347 13 7 1,000 5,434E-04 0,01054327 ! regulation of respiratory burst GO:0060263 11 7 1,000 5,434E-04 0,01045892 ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 5,434E-04 0,01037592 ! regulation of transcription factor activity GO:0051090 126 74 3,000 5,869E-04 0,01111892 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 3,000 5,869E-04 0,01103205 GO:0051327|M phase of meiotic cell cycle, ! leukocyte mediated immunity GO:0002443 128 74 3,000 5,869E-04 0,01094653 ! meiotic cell cycle GO:0051321 122 75 3,000 6,175E-04 0,01142873 ! regulation of catabolic process GO:0009894 161 76 3,000 6,492E-04 0,01192404 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 6,513E-04 0,01187126 ! placenta development GO:0001890 53 34 2,000 7,116E-04 0,01287361 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 7,221E-04 0,01296464 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,221E-04 0,0128686 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,221E-04 0,01277398 ! endothelial cell differentiation GO:0045446 17 8 1,000 7,221E-04 0,01268074 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,221E-04 0,01258885 ! ER overload response GO:0006983 12 8 1,000 7,221E-04 0,01249828 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,221E-04 0,01240901 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,221E-04 0,012321 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,221E-04 0,01223424 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 7,221E-04 0,01214868 ! leukocyte activation during immune response GO:0002366 13 8 1,000 7,221E-04 0,01206432 GO:0002263|cell activation during immune response, ! trophectodermal cell differentiation GO:0001829 13 8 1,000 7,221E-04 0,01198111 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 7,221E-04 0,01189905 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 7,221E-04 0,01181811 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 7,754E-04 0,01260588 ! cell-substrate adhesion GO:0031589 171 81 3,000 8,253E-04 0,0133273 ! DNA integrity checkpoint GO:0031570 75 36 2,000 8,427E-04 0,01351752 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 8,427E-04 0,013428 ! negative regulation of cell activation GO:0050866 65 36 2,000 8,427E-04 0,01333966 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 8,642E-04 0,01359034 ! RNA export from nucleus GO:0006405 56 37 2,000 9,137E-04 0,01427433 ! negative regulation of DNA binding GO:0043392 68 37 2,000 9,137E-04 0,01418224 ! regulation of protein stability GO:0031647 73 37 2,000 9,137E-04 0,01409133 ! regulation of developmental growth GO:0048638 15 9 1,000 9,252E-04 0,01417882 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,252E-04 0,01408908 ! induction of positive chemotaxis GO:0050930 15 9 1,000 9,252E-04 0,01400047 ! regulation of glycolysis GO:0006110 21 9 1,000 9,252E-04 0,01391297 ! keratinocyte proliferation GO:0043616 14 9 1,000 9,252E-04 0,01382655 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,252E-04 0,0137412 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 9,252E-04 0,0136569 ! receptor clustering GO:0043113 18 9 1,000 9,252E-04 0,01357363 ! motor axon guidance GO:0008045 16 9 1,000 9,252E-04 0,01349136 ! protein heterooligomerization GO:0051291 16 9 1,000 9,252E-04 0,01341009 ! response to amine stimulus GO:0014075 13 9 1,000 9,252E-04 0,01332979 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 9,252E-04 0,01325044 ! regulation of telomere maintenance GO:0032204 14 9 1,000 9,252E-04 0,01317204 ! negative regulation of growth GO:0045926 155 84 3,000 9,458E-04 0,01338634 ! carbohydrate homeostasis GO:0033500 53 38 2,000 9,882E-04 0,0139047 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 2,000 9,882E-04 0,01382386 ! mitochondrion organization GO:0007005 148 86 3,000 1,033E-03 0,0143626 ! learning GO:0007612 77 39 2,000 1,067E-03 0,01474813 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,067E-03 0,01466385 ! regulation of DNA binding GO:0051101 155 88 3,000 1,125E-03 0,01538021 ! negative regulation of binding GO:0051100 72 40 2,000 1,149E-03 0,01561484 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,153E-03 0,01557975 ! lung alveolus development GO:0048286 26 10 1,000 1,153E-03 0,01549271 ! positive regulation of muscle contraction GO:0045933 14 10 1,000 1,153E-03 0,01540664 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,153E-03 0,01532152 ! regulation of bone resorption GO:0045124 25 10 1,000 1,153E-03 0,01523734 ! DNA ligation GO:0006266 19 10 1,000 1,153E-03 0,01515407 ! protein sumoylation GO:0016925 15 10 1,000 1,153E-03 0,01507171 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 1,153E-03 0,01499024 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,153E-03 0,01490965 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,153E-03 0,01482992 GO:0043470|regulation of carbohydrate catabolic process, ! blastocyst formation GO:0001825 17 10 1,000 1,153E-03 0,01475104 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,153E-03 0,01467299 ! localization within membrane GO:0051668 20 10 1,000 1,153E-03 0,01459576 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,235E-03 0,01555409 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,235E-03 0,01547308 ! monocarboxylic acid transport GO:0015718 85 42 2,000 1,325E-03 0,01651478 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 2,000 1,325E-03 0,01642965 ! alcohol biosynthetic process GO:0046165 59 42 2,000 1,325E-03 0,0163454 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,381E-03 0,01695261 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,404E-03 0,0171473 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,404E-03 0,01706069 ! blood vessel remodeling GO:0001974 29 11 1,000 1,404E-03 0,01697496 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,404E-03 0,01689009 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,404E-03 0,01680606 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,404E-03 0,01672286 ! indolalkylamine metabolic process GO:0006586 17 11 1,000 1,404E-03 0,01664048 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of intracellular pH GO:0051453 19 11 1,000 1,404E-03 0,01655891 ! nitric oxide metabolic process GO:0046209 15 11 1,000 1,404E-03 0,01647813 GO:0006809|nitric oxide biosynthetic process, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,404E-03 0,01639814 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 1,404E-03 0,01631893 ! sequestering of metal ion GO:0051238 14 11 1,000 1,404E-03 0,01624047 ! regulation of embryonic development GO:0045995 27 11 1,000 1,404E-03 0,01616276 ! glucose transport GO:0015758 65 43 2,000 1,419E-03 0,016255 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,419E-03 0,01617796 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 1,494E-03 0,01695427 ! hexose transport GO:0008645 67 44 2,000 1,517E-03 0,01713419 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 107 44 2,000 1,517E-03 0,01705412 ! maintenance of location in cell GO:0051651 97 44 2,000 1,517E-03 0,0169748 ! leukocyte differentiation GO:0002521 202 96 3,000 1,553E-03 0,01729508 ! cell growth GO:0016049 84 45 2,000 1,619E-03 0,0179521 ! interphase GO:0051325 213 98 3,000 1,675E-03 0,01848687 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,679E-03 0,01844722 ! virus-host interaction GO:0019048 29 12 1,000 1,679E-03 0,01836337 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 1,679E-03 0,01828028 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,679E-03 0,01819793 ! regulation of cell projection assembly GO:0060491 30 12 1,000 1,679E-03 0,01811633 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,679E-03 0,01803545 ! focal adhesion formation GO:0048041 35 12 1,000 1,679E-03 0,01795529 ! mitotic spindle organization GO:0007052 21 12 1,000 1,679E-03 0,01787584 ! membrane protein proteolysis GO:0033619 25 12 1,000 1,679E-03 0,0177971 GO:0006509|membrane protein ectodomain proteolysis, ! histone acetylation GO:0016573 26 12 1,000 1,679E-03 0,01771904 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,679E-03 0,01764166 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,679E-03 0,01756496 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,951E-03 0,02032516 ! cellular component disassembly GO:0022411 86 48 2,000 1,951E-03 0,02023755 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 1,951E-03 0,0201507 ! endocrine pancreas development GO:0031018 22 13 1,000 1,978E-03 0,02033491 ! response to X-ray GO:0010165 25 13 1,000 1,978E-03 0,02024838 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,978E-03 0,02016258 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 1,978E-03 0,02007751 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,978E-03 0,01999315 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,978E-03 0,01990949 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 1,978E-03 0,01982654 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,195E-03 0,02191189 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,3E-03 0,02286244 ! embryo implantation GO:0007566 30 14 1,000 2,3E-03 0,02276836 ! response to gamma radiation GO:0010332 28 14 1,000 2,3E-03 0,02267505 ! regulation of RNA stability GO:0043487 32 14 1,000 2,3E-03 0,02258249 ! regulation of muscle contraction GO:0006937 81 52 2,000 2,456E-03 0,02402371 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 2,644E-03 0,02575862 ! phospholipid catabolic process GO:0009395 22 15 1,000 2,644E-03 0,02565476 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 1,000 2,644E-03 0,02555172 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 2,644E-03 0,02544952 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! glycoprotein catabolic process GO:0006516 26 15 1,000 2,644E-03 0,02534812 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,644E-03 0,02524754 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 2,644E-03 0,02514774 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,644E-03 0,02504874 ! muscle maintenance GO:0046716 26 15 1,000 2,644E-03 0,02495051 ! dopamine metabolic process GO:0042417 35 15 1,000 2,644E-03 0,02485304 ! positive regulation of calcium ion transport GO:0051928 19 15 1,000 2,644E-03 0,02475634 ! regulation of protein catabolic process GO:0042176 116 55 2,000 2,883E-03 0,02688811 ! heart morphogenesis GO:0003007 97 55 2,000 2,883E-03 0,0267843 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,012E-03 0,02787227 ! positive regulation of ion transport GO:0043270 21 16 1,000 3,012E-03 0,02776548 ! startle response GO:0001964 28 16 1,000 3,012E-03 0,02765951 ! intermediate filament-based process GO:0045103 32 16 1,000 3,012E-03 0,02755434 ! axon cargo transport GO:0008088 43 16 1,000 3,012E-03 0,02744997 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,012E-03 0,02734638 ! DNA replication initiation GO:0006270 27 16 1,000 3,012E-03 0,02724358 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,012E-03 0,02714154 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,012E-03 0,02704027 ! maintenance of location GO:0051235 118 57 2,000 3,192E-03 0,02854743 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,402E-03 0,03031618 ! signal complex assembly GO:0007172 41 17 1,000 3,402E-03 0,03020431 ! endothelial cell migration GO:0043542 28 17 1,000 3,402E-03 0,03009327 ! inositol metabolic process GO:0006020 28 17 1,000 3,402E-03 0,02998304 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 3,402E-03 0,02987361 ! heart looping GO:0001947 30 17 1,000 3,402E-03 0,02976498 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 3,402E-03 0,02965713 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,402E-03 0,02955007 ! regulation of striated muscle contraction GO:0006942 21 17 1,000 3,402E-03 0,02944377 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 3,402E-03 0,02933824 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 3,402E-03 0,02923346 ! DNA catabolic process GO:0006308 86 59 2,000 3,52E-03 0,0301363 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 3,52E-03 0,03002943 ! memory GO:0007613 31 18 1,000 3,814E-03 0,03242947 ! cell-substrate junction assembly GO:0007044 54 18 1,000 3,814E-03 0,03231528 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 3,814E-03 0,03220189 ! long-chain fatty acid transport GO:0015909 31 18 1,000 3,814E-03 0,0320893 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 3,814E-03 0,03197749 ! regulation of homeostatic process GO:0032844 134 62 2,000 4,049E-03 0,03382564 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 4,236E-03 0,03526188 ! regulation of postsynaptic membrane potential GO:0060078 32 19 1,000 4,249E-03 0,0352508 ! actin filament bundle formation GO:0051017 42 19 1,000 4,249E-03 0,03512966 ! neuromuscular junction development GO:0007528 34 19 1,000 4,249E-03 0,03500936 ! response to lipopolysaccharide GO:0032496 30 19 1,000 4,249E-03 0,03488987 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 4,249E-03 0,0347712 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 4,249E-03 0,03465333 ! visual learning GO:0008542 36 19 1,000 4,249E-03 0,03453626 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 4,705E-03 0,03811577 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,705E-03 0,03798786 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 4,705E-03 0,03786081 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 4,705E-03 0,03773461 ! pancreas development GO:0031016 35 20 1,000 4,705E-03 0,03760924 ! cellular response to starvation GO:0009267 33 20 1,000 4,705E-03 0,03748471 ! fatty acid beta-oxidation GO:0006635 34 20 1,000 4,705E-03 0,037361 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 4,705E-03 0,0372381 ! actin filament organization GO:0007015 148 66 2,000 4,826E-03 0,03807219 ! developmental maturation GO:0021700 116 66 2,000 4,826E-03 0,03794777 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 5,034E-03 0,03944949 ! lung development GO:0030324 144 67 2,000 5,034E-03 0,0393214 ! cell aging GO:0007569 44 21 1,000 5,183E-03 0,04035576 ! positive regulation of locomotion GO:0040017 39 21 1,000 5,183E-03 0,04022558 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! vitamin A metabolic process GO:0006776 33 21 1,000 5,183E-03 0,04009624 ! response to cytokine stimulus GO:0034097 63 21 1,000 5,183E-03 0,03996773 ! negative regulation of kinase activity GO:0033673 131 68 2,000 5,246E-03 0,04032817 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 5,246E-03 0,04019974 ! regulation of chemotaxis GO:0050920 40 22 1,000 5,682E-03 0,04339943 ! glutamate signaling pathway GO:0007215 41 22 1,000 5,682E-03 0,04326209 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 5,682E-03 0,04312561 ! positive regulation of B cell activation GO:0050871 38 22 1,000 5,682E-03 0,04299 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 5,682E-03 0,04285523 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 5,682E-03 0,04272131 ! protein stabilization GO:0050821 39 22 1,000 5,682E-03 0,04258822 ! respiratory tube development GO:0030323 150 70 2,000 5,688E-03 0,0424993 ! B cell activation GO:0042113 160 71 2,000 5,917E-03 0,04407206 ! carbohydrate transport GO:0008643 110 72 2,000 6,151E-03 0,04567551 ! negative regulation of transferase activity GO:0051348 140 72 2,000 6,151E-03 0,04553497 ! respiratory system development GO:0060541 153 72 2,000 6,151E-03 0,0453953 ! positive regulation of DNA replication GO:0045740 43 23 1,000 6,202E-03 0,04563455 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,202E-03 0,04549542 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 6,202E-03 0,04535714 ! gluconeogenesis GO:0006094 33 23 1,000 6,202E-03 0,04521969 ! visual behavior GO:0007632 42 23 1,000 6,202E-03 0,04508308 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,202E-03 0,04494728 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 1,000 6,202E-03 0,04481231 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 6,202E-03 0,04467814 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 6,202E-03 0,04454477 ! sex determination GO:0007530 47 23 1,000 6,202E-03 0,0444122 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 6,202E-03 0,04428041 ! learning or memory GO:0007611 147 73 2,000 6,391E-03 0,04549002 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 6,743E-03 0,04785964 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 6,743E-03 0,04771888 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 6,743E-03 0,04757894 ! regulation of transmembrane transport GO:0034762 38 24 1,000 6,743E-03 0,04743982 ! regulation of behavior GO:0050795 43 24 1,000 6,743E-03 0,04730151 ! membrane depolarization GO:0051899 39 24 1,000 6,743E-03 0,04716401 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 6,743E-03 0,0470273 ! cell-matrix adhesion GO:0007160 163 75 2,000 6,887E-03 0,04788718 ! lymphocyte differentiation GO:0030098 167 75 2,000 6,887E-03 0,04774918 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 7,305E-03 0,05050585 ! myelination GO:0042552 45 25 1,000 7,305E-03 0,05036114 ! vasculogenesis GO:0001570 46 25 1,000 7,305E-03 0,05021725 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 7,305E-03 0,05007418 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 7,305E-03 0,04993192 ! response to starvation GO:0042594 42 25 1,000 7,305E-03 0,04979047 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 7,305E-03 0,04964982 ! negative regulation of cell development GO:0010721 73 25 1,000 7,305E-03 0,04950996 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 7,305E-03 0,04937089 ! somitogenesis GO:0001756 43 25 1,000 7,305E-03 0,0492326 ! cellular response to nutrient levels GO:0031669 41 25 1,000 7,305E-03 0,04909508 ! protein oligomerization GO:0051259 139 78 2,000 7,672E-03 0,05141947 ! pyruvate metabolic process GO:0006090 38 26 1,000 7,887E-03 0,05271337 ! molting cycle process GO:0022404 50 26 1,000 7,887E-03 0,05256735 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 7,887E-03 0,05242214 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 7,887E-03 0,05227773 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 7,887E-03 0,05213411 ! positive regulation of nuclear division GO:0051785 40 26 1,000 7,887E-03 0,05199127 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 7,887E-03 0,05184922 ! cellular lipid catabolic process GO:0044242 134 80 2,000 8,224E-03 0,05391793 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 8,49E-03 0,05550602 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 8,49E-03 0,0553556 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 8,49E-03 0,05520599 ! protein amino acid acylation GO:0043543 55 27 1,000 8,49E-03 0,05505718 ! fat cell differentiation GO:0045444 50 27 1,000 8,49E-03 0,05490918 ! mitochondrial membrane organization GO:0007006 57 27 1,000 8,49E-03 0,05476197 ! base-excision repair GO:0006284 41 27 1,000 8,49E-03 0,05461555 ! fat-soluble vitamin metabolic process GO:0006775 40 27 1,000 8,49E-03 0,05446991 ! response to hypoxia GO:0001666 171 81 2,000 8,509E-03 0,05444834 ! response to drug GO:0042493 143 82 2,000 8,799E-03 0,05615664 ! response to oxygen levels GO:0070482 176 83 2,000 9,095E-03 0,05789252 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 9,112E-03 0,0578462 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 9,112E-03 0,05769397 ! lipid oxidation GO:0034440 43 28 1,000 9,112E-03 0,05754254 GO:0019395|fatty acid oxidation, ! regulation of pH GO:0006885 43 29 1,000 9,754E-03 0,06143657 ! catechol metabolic process GO:0009712 54 29 1,000 9,754E-03 0,06127616 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! immune response-activating signal transduction GO:0002757 47 29 1,000 9,754E-03 0,06111659 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 60 29 1,000 9,754E-03 0,06095784 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 9,754E-03 0,06079992 ! phenol metabolic process GO:0018958 55 30 1,000 0,01041599 0,06475678 ! cell junction assembly GO:0034329 78 30 1,000 0,01041599 0,06458988 ! response to heat GO:0009408 50 30 1,000 0,01041599 0,06442384 ! gland development GO:0048732 206 88 2,000 0,01066268 0,06578052 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,0109937 0,06764922 ! fatty acid catabolic process GO:0009062 48 31 1,000 0,01109705 0,06811097 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01133062 0,06936761 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01179723 0,07204096 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01179723 0,07185858 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01179723 0,07167712 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01179723 0,07149657 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01179723 0,07131693 ! regulation of calcium ion transport GO:0051924 53 32 1,000 0,01179723 0,07113819 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01179723 0,07096035 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01251632 0,07509795 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01251632 0,07491114 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01273759 0,07604624 ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,01325412 0,07893418 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01325412 0,07873928 ! mRNA transport GO:0051028 169 96 2,000 0,01347686 0,07986533 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,0140104 0,08282316 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,0140104 0,08262017 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,0140104 0,08241816 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,0140104 0,08221714 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,0140104 0,0820171 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,0140104 0,08181803 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01463081 0,08523421 GO:0060538|skeletal muscle organ development, ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01478497 0,08592425 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01478497 0,0857172 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 86 36 1,000 0,01478497 0,08551115 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01478497 0,08530609 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01478497 0,08510201 ! meiosis I GO:0007127 65 37 1,000 0,01557762 0,08945047 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01557762 0,0892375 ! tissue remodeling GO:0048771 76 37 1,000 0,01557762 0,08902553 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01557762 0,08881457 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01638814 0,0932148 ! regulation of metal ion transport GO:0010959 63 38 1,000 0,01638814 0,09299496 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01638814 0,09277614 ! lipid homeostasis GO:0055088 67 38 1,000 0,01638814 0,09255836 ! isoprenoid metabolic process GO:0006720 66 38 1,000 0,01638814 0,0923416 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01638814 0,09212584 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,01721633 0,09655593 ! ear morphogenesis GO:0042471 60 39 1,000 0,01721633 0,09633138 ! segmentation GO:0035282 67 39 1,000 0,01721633 0,09610787 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,01721633 0,0958854 ! feeding behavior GO:0007631 59 40 1,000 0,01806199 0,10036296 ! maintenance of protein location GO:0045185 91 40 1,000 0,01806199 0,1001317 ! cytokinesis GO:0000910 72 40 1,000 0,01806199 0,09990152 ! T cell differentiation GO:0030217 81 41 1,000 0,01892493 0,10443436 ! polyol metabolic process GO:0019751 66 41 1,000 0,01892493 0,10419538 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01980494 0,10879151 GO:0090047|positive regulation of transcription regulator activity, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01980494 0,1085437 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02070183 0,11320135 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02070183 0,11294465 ! double-strand break repair GO:0006302 81 44 1,000 0,02161539 0,11766208 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02161539 0,11739648 ! developmental growth GO:0048589 82 44 1,000 0,02161539 0,11713207 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02254545 0,12189744 ! pigmentation GO:0043473 100 46 1,000 0,02349181 0,12672937 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02349181 0,12644586 ! endosome transport GO:0016197 108 47 1,000 0,02445428 0,13133257 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02445428 0,13104007 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02445428 0,13074887 ! JNK cascade GO:0007254 91 47 1,000 0,02445428 0,13045896 ! mitochondrial transport GO:0006839 82 48 1,000 0,02543266 0,13537829 ! Notch signaling pathway GO:0007219 96 48 1,000 0,02543266 0,13507944 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02547113 0,13498579 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02547113 0,13468912 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02547113 0,13439375 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02547113 0,13409967 ! neuron fate determination GO:0048664 7 5 0,000 0,02547113 0,13380688 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02547113 0,13351536 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02547113 0,13322511 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02547113 0,13293611 ! polyol transport GO:0015791 12 5 0,000 0,02547113 0,13264837 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02547113 0,13236188 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02547113 0,13207661 ! response to superoxide GO:0000303 10 5 0,000 0,02547113 0,13179258 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02547113 0,13150976 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02547113 0,13122816 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02547113 0,13094775 ! female meiosis GO:0007143 7 5 0,000 0,02547113 0,13066855 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02547113 0,13039053 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02547113 0,13011369 ! cobalt ion transport GO:0006824 11 5 0,000 0,02547113 0,12983803 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02547113 0,12956353 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02547113 0,12929019 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02547113 0,129018 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02547113 0,12874695 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02547113 0,12847704 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02547113 0,12820826 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02547113 0,1279406 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02547113 0,12767406 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02547113 0,12740863 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02547113 0,12714429 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02547113 0,12688105 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02547113 0,1266189 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02547113 0,12635783 ! negative chemotaxis GO:0050919 14 5 0,000 0,02547113 0,12609784 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02547113 0,12583891 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02547113 0,12558104 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02547113 0,12532423 ! behavioral response to pain GO:0048266 9 5 0,000 0,02547113 0,12506847 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02547113 0,12481374 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02547113 0,12456006 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02547113 0,1243074 ! micturition GO:0060073 9 5 0,000 0,02547113 0,12405577 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02547113 0,12380515 ! copulation GO:0007620 9 5 0,000 0,02547113 0,12355554 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02547113 0,12330694 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02547113 0,12305933 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02547113 0,12281272 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02547113 0,1225671 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02547113 0,12232245 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02547113 0,12207878 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02547113 0,12183608 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02547113 0,12159434 ! grooming behavior GO:0007625 6 5 0,000 0,02547113 0,12135356 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02547113 0,12111373 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02547113 0,12087485 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02547113 0,12063691 ! response to protozoan GO:0001562 10 5 0,000 0,02547113 0,1203999 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02547113 0,12016382 ! endochondral ossification GO:0001958 16 5 0,000 0,02547113 0,11992867 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02547113 0,11969443 ! parathyroid gland development GO:0060017 13 5 0,000 0,02547113 0,11946111 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02547113 0,11922869 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02547113 0,11899718 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02547113 0,11876657 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02547113 0,11853684 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02547113 0,11830801 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02547113 0,11808006 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02547113 0,11785298 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02547113 0,11762677 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02547113 0,11740143 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02547113 0,11717696 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02547113 0,11695334 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02547113 0,11673057 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02547113 0,11650865 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02547113 0,11628757 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02547113 0,11606733 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02547113 0,11584792 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02547113 0,11562934 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02547113 0,11541158 ! histidine catabolic process GO:0006548 6 5 0,000 0,02547113 0,11519464 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02547113 0,11497852 ! valine metabolic process GO:0006573 10 5 0,000 0,02547113 0,1147632 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02547113 0,11454869 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02547113 0,11433498 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02547113 0,11412206 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02547113 0,11390994 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02547113 0,11369861 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02547113 0,11348805 ! polyol catabolic process GO:0046174 7 5 0,000 0,02547113 0,11327828 GO:0019405|alditol catabolic process, ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02547113 0,11306928 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02547113 0,11286105 ! muscle cell migration GO:0014812 8 5 0,000 0,02547113 0,11265358 ! mitochondrial fission GO:0000266 8 5 0,000 0,02547113 0,11244688 ! mRNA transcription GO:0009299 9 5 0,000 0,02547113 0,11224093 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02547113 0,11203574 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02547113 0,11183129 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02547113 0,11162759 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02547113 0,11142463 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02547113 0,11122241 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02547113 0,11102092 ! response to food GO:0032094 6 5 0,000 0,02547113 0,11082016 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02547113 0,11062012 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02547113 0,11042081 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02547113 0,11022221 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02547113 0,11002432 ! forebrain neuron development GO:0021884 13 5 0,000 0,02547113 0,10982715 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02547113 0,10963068 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02547113 0,10943491 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02547113 0,10923984 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02547113 0,10904546 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02547113 0,10885177 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02547113 0,10865877 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02547113 0,10846646 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02547113 0,10827482 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02547113 0,10808386 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02547113 0,10789357 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02547113 0,10770395 ! basic amino acid transport GO:0015802 11 5 0,000 0,02547113 0,107515 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02547113 0,10732671 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02547113 0,10713907 ! depyrimidination GO:0045008 10 5 0,000 0,02547113 0,10695209 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02547113 0,10676576 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02547113 0,10658008 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02547113 0,10639505 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02547113 0,10621066 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02547113 0,1060269 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02547113 0,10584378 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02547113 0,10566129 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02547113 0,10547943 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02547113 0,10529819 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02547113 0,10511758 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02547113 0,10493758 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02547113 0,1047582 ! response to arsenic GO:0046685 10 5 0,000 0,02547113 0,10457943 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02547113 0,10440128 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02547113 0,10422372 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02547113 0,10404677 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02547113 0,10387042 ! response to cadmium ion GO:0046686 7 5 0,000 0,02547113 0,10369467 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02547113 0,10351951 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02547113 0,10334494 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02547113 0,10317096 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02547113 0,10299756 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02547113 0,10282475 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02547113 0,10265251 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02547113 0,10248085 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02547113 0,10230976 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02547113 0,10213925 ! neural tube patterning GO:0021532 7 5 0,000 0,02547113 0,1019693 ! embryonic cleavage GO:0040016 6 5 0,000 0,02547113 0,10179991 ! peroxisome fission GO:0016559 5 5 0,000 0,02547113 0,10163109 ! histone demethylation GO:0016577 10 5 0,000 0,02547113 0,10146283 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02547113 0,10129512 ! mitotic recombination GO:0006312 9 5 0,000 0,02547113 0,10112797 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02547113 0,10096137 ! metaphase plate congression GO:0051310 7 5 0,000 0,02547113 0,10079531 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02547113 0,1006298 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02547113 0,10046483 ! enteric nervous system development GO:0048484 8 5 0,000 0,02547113 0,10030041 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02547113 0,10013652 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02547113 0,09997316 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02547113 0,09981034 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02547113 0,09964805 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02547113 0,09948628 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02547113 0,09932504 ! plasminogen activation GO:0031639 5 5 0,000 0,02547113 0,09916432 ! B cell homeostasis GO:0001782 13 5 0,000 0,02547113 0,09900412 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02547113 0,09884443 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02547113 0,09868526 ! metaphase GO:0051323 8 5 0,000 0,02547113 0,09852661 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02547113 0,09836846 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02547113 0,09821082 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02547113 0,09805368 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02547113 0,09789704 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02547113 0,09774091 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02547113 0,09758527 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02547113 0,09743013 ! response to redox state GO:0051775 5 5 0,000 0,02547113 0,09727547 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02547113 0,09712131 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02547113 0,09696764 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02547113 0,09681445 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02547113 0,09666175 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02547113 0,09650953 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02547113 0,09635778 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02547113 0,09620651 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02547113 0,09605572 ! striatum development GO:0021756 9 5 0,000 0,02547113 0,0959054 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02547113 0,09575554 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02547113 0,09560616 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02547113 0,09545724 ! glial cell migration GO:0008347 11 5 0,000 0,02547113 0,09530879 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02547113 0,09516079 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02547113 0,09501325 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02547113 0,09486617 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02547113 0,09471955 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02547113 0,09457338 ! neuroprotection GO:0043526 6 5 0,000 0,02547113 0,09442766 ! neural plate development GO:0001840 8 5 0,000 0,02547113 0,09428238 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02547113 0,09413756 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02547113 0,09399317 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02547113 0,09384923 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02547113 0,09370573 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02547113 0,09356267 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02547113 0,09342004 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02547113 0,09327785 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02547113 0,09313609 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02547113 0,09299476 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 6 5 0,000 0,02547113 0,09285386 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02547113 0,09271339 ! organ regeneration GO:0031100 7 5 0,000 0,02547113 0,09257334 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02547113 0,09243371 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02547113 0,0922945 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02547113 0,09215571 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,02642678 0,09546972 ! regulation of ion transport GO:0043269 77 49 1,000 0,02642678 0,09532659 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,02642678 0,09518388 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02642678 0,0950416 ! endocrine system development GO:0035270 104 49 1,000 0,02642678 0,09489975 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,02642678 0,09475832 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,02642678 0,09461731 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,02743644 0,09808631 ! neuromuscular process GO:0050905 99 50 1,000 0,02743644 0,09794078 ! histone modification GO:0016570 91 50 1,000 0,02743644 0,09779568 ! positive regulation of binding GO:0051099 78 51 1,000 0,02846147 0,10129926 ! regulation of cell shape GO:0008360 125 51 1,000 0,02846147 0,10114963 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,02950168 0,1046918 ! positive regulation of growth GO:0045927 90 52 1,000 0,02950168 0,10453761 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02950168 0,10438388 ! synapse organization GO:0050808 85 52 1,000 0,02950168 0,1042306 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03048747 0,10755551 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03048747 0,10739804 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03048747 0,10724102 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03048747 0,10708446 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03048747 0,10692836 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03048747 0,10677272 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03048747 0,10661753 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03048747 0,10646278 ! response to oxygen radical GO:0000305 11 6 0,000 0,03048747 0,10630849 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03048747 0,10615464 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03048747 0,10600124 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03048747 0,10584828 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03048747 0,10569576 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03048747 0,10554368 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03048747 0,10539204 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03048747 0,10524083 ! forebrain regionalization GO:0021871 8 6 0,000 0,03048747 0,10509005 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03048747 0,10493971 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03048747 0,1047898 ! response to zinc ion GO:0010043 9 6 0,000 0,03048747 0,10464031 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03048747 0,10449125 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03048747 0,10434262 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03048747 0,1041944 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03048747 0,10404661 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03048747 0,10389923 ! malate metabolic process GO:0006108 11 6 0,000 0,03048747 0,10375227 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03048747 0,10360573 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03048747 0,1034596 ! protein refolding GO:0042026 15 6 0,000 0,03048747 0,10331389 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03048747 0,10316858 ! opsonization GO:0008228 8 6 0,000 0,03048747 0,10302368 ! mating behavior GO:0007617 7 6 0,000 0,03048747 0,10287918 ! neuron remodeling GO:0016322 15 6 0,000 0,03048747 0,1027351 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03048747 0,10259141 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03048747 0,10244813 ! equilibrioception GO:0050957 14 6 0,000 0,03048747 0,10230524 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03048747 0,10216276 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03048747 0,10202067 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03048747 0,10187897 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03048747 0,10173767 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03048747 0,10159676 ! toxin metabolic process GO:0009404 11 6 0,000 0,03048747 0,10145624 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03048747 0,1013161 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03048747 0,10117636 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03048747 0,10103699 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03048747 0,10089802 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03048747 0,10075942 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03048747 0,1006212 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03048747 0,10048337 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03048747 0,10034591 ! thymic T cell selection GO:0045061 12 6 0,000 0,03048747 0,10020882 ! protein lipoylation GO:0009249 10 6 0,000 0,03048747 0,10007211 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03048747 0,09993577 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03048747 0,09979981 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03048747 0,09966421 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03048747 0,09952898 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03048747 0,09939412 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03048747 0,09925962 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03048747 0,09912548 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03048747 0,09899171 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03048747 0,0988583 ! hyperosmotic response GO:0006972 9 6 0,000 0,03048747 0,09872525 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03048747 0,09859255 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03048747 0,09846021 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03048747 0,09832823 ! urea metabolic process GO:0019627 7 6 0,000 0,03048747 0,0981966 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03048747 0,09806532 ! neutrophil activation GO:0042119 8 6 0,000 0,03048747 0,09793439 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03048747 0,09780381 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03048747 0,09767358 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03048747 0,09754369 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03048747 0,09741415 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03048747 0,09728496 ! neuron apoptosis GO:0051402 9 6 0,000 0,03048747 0,0971561 ! nucleoside salvage GO:0043174 9 6 0,000 0,03048747 0,09702759 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03048747 0,09689942 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03048747 0,09677158 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03048747 0,09664408 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03048747 0,09651692 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03048747 0,09639009 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03048747 0,09626359 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03048747 0,09613743 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03048747 0,09601159 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03048747 0,09588609 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03048747 0,09576091 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03048747 0,09563606 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03048747 0,09551153 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03048747 0,09538733 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03048747 0,09526345 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03048747 0,09513989 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03048747 0,09501666 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 0,000 0,03048747 0,09489374 ! response to UV-C GO:0010225 11 6 0,000 0,03048747 0,09477113 ! astrocyte development GO:0014002 15 6 0,000 0,03048747 0,09464885 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03048747 0,09452688 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03048747 0,09440522 ! interaction with symbiont GO:0051702 13 6 0,000 0,03048747 0,09428388 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03048747 0,09416285 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03048747 0,09404213 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03048747 0,09392171 ! response to copper ion GO:0046688 10 6 0,000 0,03048747 0,09380161 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03048747 0,09368181 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03048747 0,09356232 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03048747 0,09344313 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03048747 0,09332425 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03048747 0,09320567 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03048747 0,09308738 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03048747 0,0929694 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03048747 0,09285172 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03048747 0,09273433 ! Schwann cell development GO:0014044 15 6 0,000 0,03048747 0,09261725 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03048747 0,09250045 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03048747 0,09238395 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03048747 0,09226775 ! subpallium development GO:0021544 10 6 0,000 0,03048747 0,09215183 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03048747 0,09203621 ! histone ubiquitination GO:0016574 8 6 0,000 0,03048747 0,09192088 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03048747 0,09180583 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03048747 0,09169107 ! G2 phase GO:0051319 16 6 0,000 0,03048747 0,0915766 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03048747 0,09146242 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03048747 0,09134852 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03048747 0,0912349 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03048747 0,09112156 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03048747 0,09100851 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03048747 0,09089574 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03048747 0,09078324 ! receptor internalization GO:0031623 10 6 0,000 0,03048747 0,09067102 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03048747 0,09055908 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03048747 0,09044742 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03048747 0,09033603 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03048747 0,09022492 ! protein deubiquitination GO:0016579 14 6 0,000 0,03048747 0,09011408 ! protein destabilization GO:0031648 9 6 0,000 0,03048747 0,09000351 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03048747 0,08989321 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03048747 0,08978318 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03048747 0,08967342 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03048747 0,08956393 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03048747 0,08945471 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03048747 0,08934575 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03048747 0,08923705 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03048747 0,08912862 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03048747 0,08902046 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03048747 0,08891256 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03048747 0,08880491 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03048747 0,08869753 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03048747 0,08859041 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03048747 0,08848354 ! catecholamine transport GO:0051937 9 6 0,000 0,03048747 0,08837694 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03048747 0,08827059 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03048747 0,08816449 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03048747 0,08805865 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03048747 0,08795307 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03048747 0,08784773 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03048747 0,08774265 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03048747 0,08763782 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03048747 0,08753324 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03048747 0,08742891 ! regulation of translational initiation GO:0006446 82 53 1,000 0,03055689 0,08752365 ! cell maturation GO:0048469 100 53 1,000 0,03055689 0,08741958 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03055689 0,08731576 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03162691 0,09026613 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03271158 0,09325125 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03381071 0,09627048 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,03381071 0,09615669 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03381071 0,09604316 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,03492412 0,09908897 ! muscle fiber development GO:0048747 112 57 1,000 0,03492412 0,09897225 ! lipid modification GO:0030258 97 57 1,000 0,03492412 0,09885581 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03492412 0,09873965 ! tRNA transcription GO:0009304 14 7 0,000 0,03547815 0,10018831 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03547815 0,10007086 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03547815 0,09995368 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03547815 0,09983677 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03547815 0,09972014 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03547815 0,09960378 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03547815 0,09948769 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03547815 0,09937187 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03547815 0,09925633 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03547815 0,09914105 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03547815 0,09902603 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03547815 0,09891129 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03547815 0,09879681 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03547815 0,09868259 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03547815 0,09856864 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03547815 0,09845495 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03547815 0,09834152 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03547815 0,09822836 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03547815 0,09811545 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03547815 0,0980028 ! glycolipid transport GO:0046836 10 7 0,000 0,03547815 0,09789041 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03547815 0,09777828 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03547815 0,09766641 ! neuron adhesion GO:0007158 12 7 0,000 0,03547815 0,09755479 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03547815 0,09744343 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03547815 0,09733232 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03547815 0,09722146 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03547815 0,09711085 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03547815 0,0970005 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03547815 0,0968904 ! pericardium development GO:0060039 14 7 0,000 0,03547815 0,09678054 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03547815 0,09667094 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03547815 0,09656158 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03547815 0,09645248 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03547815 0,09634361 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03547815 0,09623499 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03547815 0,09612662 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03547815 0,09601849 ! rhythmic behavior GO:0007622 15 7 0,000 0,03547815 0,09591061 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03547815 0,09580296 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03547815 0,09569556 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03547815 0,0955884 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03547815 0,09548148 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03547815 0,09537479 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03547815 0,09526835 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03547815 0,09516214 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03547815 0,09505617 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03547815 0,09495043 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03547815 0,09484493 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03547815 0,09473967 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03547815 0,09463463 ! spinal cord patterning GO:0021511 13 7 0,000 0,03547815 0,09452983 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03547815 0,09442527 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03547815 0,09432093 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03547815 0,09421682 ! adrenal gland development GO:0030325 17 7 0,000 0,03547815 0,09411294 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03547815 0,0940093 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03547815 0,09390588 ! ovulation GO:0030728 9 7 0,000 0,03547815 0,09380268 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03547815 0,09369972 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03547815 0,09359697 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03547815 0,09349446 ! microtubule nucleation GO:0007020 20 7 0,000 0,03547815 0,09339217 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03547815 0,0932901 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03547815 0,09318825 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03547815 0,09308663 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03547815 0,09298523 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03547815 0,09288405 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03547815 0,09278309 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03547815 0,09268235 ! galactose metabolic process GO:0006012 13 7 0,000 0,03547815 0,09258182 ! vesicle fusion GO:0006906 17 7 0,000 0,03547815 0,09248152 ! response to dietary excess GO:0002021 8 7 0,000 0,03547815 0,09238143 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03547815 0,09228156 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03547815 0,0921819 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03547815 0,09208246 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03547815 0,09198323 ! organ growth GO:0035265 15 7 0,000 0,03547815 0,09188422 ! purine salvage GO:0043101 10 7 0,000 0,03547815 0,09178542 ! nucleoside transport GO:0015858 8 7 0,000 0,03547815 0,09168683 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03547815 0,09158846 ! parturition GO:0007567 14 7 0,000 0,03547815 0,09149029 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03547815 0,09139233 ! rRNA modification GO:0000154 14 7 0,000 0,03547815 0,09129459 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03547815 0,09119705 ! spindle checkpoint GO:0031577 15 7 0,000 0,03547815 0,09109972 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03547815 0,0910026 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03547815 0,09090569 ! macrophage differentiation GO:0030225 11 7 0,000 0,03547815 0,09080898 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03547815 0,09071248 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03547815 0,09061618 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03547815 0,09052009 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03547815 0,0904242 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03547815 0,09032851 ! fibrinolysis GO:0042730 10 7 0,000 0,03547815 0,09023302 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03547815 0,09013774 ! eating behavior GO:0042755 7 7 0,000 0,03547815 0,09004266 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03547815 0,08994778 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03547815 0,0898531 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03547815 0,08975861 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03547815 0,08966433 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03547815 0,08957024 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03547815 0,08947635 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03547815 0,08938266 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03547815 0,08928916 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03547815 0,08919586 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03547815 0,08910276 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03547815 0,08900984 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03547815 0,08891713 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03547815 0,0888246 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03547815 0,08873227 ! regulation of meiosis GO:0040020 12 7 0,000 0,03547815 0,08864013 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03547815 0,08854817 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03547815 0,08845642 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03547815 0,08836485 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03547815 0,08827346 ! transcription termination GO:0006353 13 7 0,000 0,03547815 0,08818227 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03547815 0,08809127 ! anaphase GO:0051322 17 7 0,000 0,03547815 0,08800045 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03547815 0,08790983 ! axonal fasciculation GO:0007413 18 7 0,000 0,03547815 0,08781938 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03547815 0,08772913 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03547815 0,08763906 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03547815 0,08754917 ! diuresis GO:0030146 12 7 0,000 0,03547815 0,08745947 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03547815 0,08736995 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03547815 0,08728061 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03547815 0,08719146 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03547815 0,08710249 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03547815 0,0870137 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03547815 0,08692509 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03547815 0,08683666 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03547815 0,08674842 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03547815 0,08666035 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03547815 0,08657245 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03547815 0,08648474 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03547815 0,08639721 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03547815 0,08630985 ! lymph node development GO:0048535 10 7 0,000 0,03547815 0,08622267 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03547815 0,08613566 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03547815 0,08604883 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03547815 0,08596218 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03547815 0,08587569 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03547815 0,08578939 ! adult feeding behavior GO:0008343 9 7 0,000 0,03547815 0,08570325 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03547815 0,08561729 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03547815 0,0855315 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03547815 0,08544589 ! muscle adaptation GO:0043500 14 7 0,000 0,03547815 0,08536044 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03547815 0,08527517 ! retina homeostasis GO:0001895 12 7 0,000 0,03547815 0,08519006 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03547815 0,08510513 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03547815 0,08502036 ! protein prenylation GO:0018342 18 7 0,000 0,03547815 0,08493576 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03547815 0,08485133 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03547815 0,08476707 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03547815 0,08468298 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,03605166 0,08596659 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03605166 0,08588147 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,03719313 0,08851303 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,03719313 0,08842556 ! establishment of organelle localization GO:0051656 109 59 1,000 0,03719313 0,08833827 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,03834837 0,09099229 ! regulation of heart contraction GO:0008016 110 60 1,000 0,03834837 0,09090265 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04044331 0,09577422 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04044331 0,09568005 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04044331 0,09558606 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04044331 0,09549226 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04044331 0,09539864 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04044331 0,0953052 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04044331 0,09521195 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04044331 0,09511887 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04044331 0,09502599 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04044331 0,09493328 ! meiotic prophase I GO:0007128 13 8 0,000 0,04044331 0,09484075 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04044331 0,0947484 ! oligopeptide transport GO:0006857 15 8 0,000 0,04044331 0,09465623 ! UTP metabolic process GO:0046051 8 8 0,000 0,04044331 0,09456425 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04044331 0,09447244 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04044331 0,0943808 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04044331 0,09428935 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04044331 0,09419807 ! succinate metabolic process GO:0006105 14 8 0,000 0,04044331 0,09410697 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04044331 0,09401605 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04044331 0,0939253 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04044331 0,09383472 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04044331 0,09374432 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04044331 0,0936541 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04044331 0,09356405 ! reflex GO:0060004 16 8 0,000 0,04044331 0,09347417 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04044331 0,09338446 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04044331 0,09329493 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04044331 0,09320556 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04044331 0,09311637 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04044331 0,09302735 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04044331 0,0929385 ! pigment granule organization GO:0048753 16 8 0,000 0,04044331 0,09284982 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04044331 0,09276131 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04044331 0,09267296 ! histidine metabolic process GO:0006547 16 8 0,000 0,04044331 0,09258478 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04044331 0,09249678 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04044331 0,09240894 ! glycine catabolic process GO:0006546 13 8 0,000 0,04044331 0,09232126 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04044331 0,09223375 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04044331 0,09214641 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04044331 0,09205923 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04044331 0,09197222 ! melanin metabolic process GO:0006582 15 8 0,000 0,04044331 0,09188537 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04044331 0,09179869 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04044331 0,09171217 ! macrophage activation GO:0042116 12 8 0,000 0,04044331 0,09162581 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04044331 0,09153961 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04044331 0,09145358 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04044331 0,09136771 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04044331 0,091282 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04044331 0,09119645 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04044331 0,09111106 ! osteoblast development GO:0002076 16 8 0,000 0,04044331 0,09102583 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04044331 0,09094076 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04044331 0,09085584 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04044331 0,09077109 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04044331 0,09068649 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04044331 0,09060206 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04044331 0,09051778 ! response to UV-B GO:0010224 16 8 0,000 0,04044331 0,09043365 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04044331 0,09034968 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04044331 0,09026587 ! intermediate filament organization GO:0045109 12 8 0,000 0,04044331 0,09018221 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04044331 0,09009871 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04044331 0,09001536 ! cellular extravasation GO:0045123 12 8 0,000 0,04044331 0,08993217 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04044331 0,08984913 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04044331 0,08976624 ! response to antibiotic GO:0046677 11 8 0,000 0,04044331 0,08968351 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04044331 0,08960093 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04044331 0,0895185 ! DNA topological change GO:0006265 12 8 0,000 0,04044331 0,08943622 ! response to tropane GO:0014073 15 8 0,000 0,04044331 0,08935409 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04044331 0,08927212 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04044331 0,08919029 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04044331 0,08910862 ! mast cell activation GO:0045576 14 8 0,000 0,04044331 0,08902709 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04044331 0,08894571 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04044331 0,08886448 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04044331 0,0887834 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04044331 0,08870247 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04044331 0,08862168 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04044331 0,08854105 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04044331 0,08846055 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04044331 0,08838021 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04044331 0,08830001 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04044331 0,08821995 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04044331 0,08814004 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04044331 0,08806028 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04044331 0,08798066 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04044331 0,08790118 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04044331 0,08782185 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04044331 0,08774266 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04044331 0,08766361 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04044331 0,08758471 ! hormone catabolic process GO:0042447 17 8 0,000 0,04044331 0,08750594 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04044331 0,08742732 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04044331 0,08734884 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04044331 0,0872705 ! ATP catabolic process GO:0006200 11 8 0,000 0,04044331 0,0871923 ! blastocyst growth GO:0001832 19 8 0,000 0,04044331 0,08711424 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04044331 0,08703632 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04044331 0,08695854 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04044331 0,0868809 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04044331 0,0868034 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04044331 0,08672603 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04044331 0,08664881 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04044331 0,08657172 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04044331 0,08649476 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04044331 0,08641795 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04044331 0,08634127 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04044331 0,08626472 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04044331 0,08618832 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04044331 0,08611204 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04044331 0,08603591 ! ear development GO:0043583 103 62 1,000 0,04069949 0,0865044 ! viral reproductive process GO:0022415 126 62 1,000 0,04069949 0,08642805 ! regulation of mitosis GO:0007088 105 63 1,000 0,04189503 0,0888884 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,04189503 0,08881009 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,04432524 0,09387899 ! axon extension GO:0048675 15 9 0,000 0,04538307 0,0960349 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04538307 0,09595051 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04538307 0,09586626 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04538307 0,09578217 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04538307 0,09569823 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04538307 0,09561443 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04538307 0,09553077 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04538307 0,09544727 ! phosphate transport GO:0006817 19 9 0,000 0,04538307 0,09536391 ! reproductive behavior GO:0019098 19 9 0,000 0,04538307 0,09528069 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04538307 0,09519762 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04538307 0,0951147 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04538307 0,09503192 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04538307 0,09494928 ! GTP metabolic process GO:0046039 9 9 0,000 0,04538307 0,09486679 ! RNA methylation GO:0001510 15 9 0,000 0,04538307 0,09478444 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04538307 0,09470223 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04538307 0,09462017 ! artery development GO:0060840 24 9 0,000 0,04538307 0,09453825 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04538307 0,09445647 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04538307 0,09437483 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04538307 0,09429333 ! chemosensory behavior GO:0007635 20 9 0,000 0,04538307 0,09421197 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04538307 0,09413075 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04538307 0,09404968 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04538307 0,09396874 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04538307 0,09388794 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04538307 0,09380728 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04538307 0,09372676 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04538307 0,09364638 ! protein targeting to ER GO:0045047 22 9 0,000 0,04538307 0,09356613 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04538307 0,09348602 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04538307 0,09340605 ! T cell selection GO:0045058 23 9 0,000 0,04538307 0,09332622 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,04538307 0,09324652 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04538307 0,09316696 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04538307 0,09308753 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04538307 0,09300824 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04538307 0,09292909 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04538307 0,09285006 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04538307 0,09277118 ! mannose metabolic process GO:0006013 13 9 0,000 0,04538307 0,09269242 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04538307 0,0926138 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04538307 0,09253532 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04538307 0,09245697 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04538307 0,09237874 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04538307 0,09230066 ! ruffle organization GO:0031529 15 9 0,000 0,04538307 0,0922227 ! retinol metabolic process GO:0042572 18 9 0,000 0,04538307 0,09214487 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04538307 0,09206718 ! behavioral fear response GO:0001662 22 9 0,000 0,04538307 0,09198962 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04538307 0,09191218 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04538307 0,09183488 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04538307 0,09175771 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04538307 0,09168067 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04538307 0,09160375 ! segment specification GO:0007379 13 9 0,000 0,04538307 0,09152697 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04538307 0,09145031 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04538307 0,09137379 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04538307 0,09129739 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04538307 0,09122112 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04538307 0,09114497 ! erythrocyte development GO:0048821 15 9 0,000 0,04538307 0,09106895 ! gas homeostasis GO:0033483 16 9 0,000 0,04538307 0,09099306 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04538307 0,0909173 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04538307 0,09084166 ! renal water homeostasis GO:0003091 14 9 0,000 0,04538307 0,09076615 ! postreplication repair GO:0006301 22 9 0,000 0,04538307 0,09069076 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04538307 0,0906155 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04538307 0,09054036 ! icosanoid secretion GO:0032309 15 9 0,000 0,04538307 0,09046535 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04538307 0,09039046 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04538307 0,0903157 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04538307 0,09024105 ! regulation of cell division GO:0051302 15 9 0,000 0,04538307 0,09016654 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04538307 0,09009214 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04538307 0,09001787 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04538307 0,08994372 ! sterol catabolic process GO:0016127 11 9 0,000 0,04538307 0,08986969 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04538307 0,08979579 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04538307 0,089722 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04538307 0,08964834 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04538307 0,0895748 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04538307 0,08950137 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04538307 0,08942807 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04538307 0,08935489 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04538307 0,08928183 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04538307 0,08920889 ! purine base metabolic process GO:0006144 21 9 0,000 0,04538307 0,08913606 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04538307 0,08906336 ! pigment granule transport GO:0051904 17 9 0,000 0,04538307 0,08899077 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04538307 0,0889183 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04538307 0,08884595 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04538307 0,08877372 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04538307 0,0887016 ! mitochondrion localization GO:0051646 15 9 0,000 0,04538307 0,08862961 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,04555959 0,08890216 ! cell projection assembly GO:0030031 120 66 1,000 0,04555959 0,08883012 ! activation of MAPK activity GO:0000187 115 67 1,000 0,04680654 0,09118747 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,04680654 0,0911137 ! adaptive immune response GO:0002250 119 67 1,000 0,04680654 0,09104004 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,04680654 0,0909665 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,04806594 0,0933387 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,04806594 0,09326342 ! regulation of lipase activity GO:0060191 130 68 1,000 0,04806594 0,09318827 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,04806594 0,09311324 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,04933763 0,09549986 ! urogenital system development GO:0001655 137 69 1,000 0,04933763 0,09542309 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05029757 0,09720157 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05029757 0,09712356 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05029757 0,09704567 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05029757 0,09696791 ! synapsis GO:0007129 13 10 0,000 0,05029757 0,09689027 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05029757 0,09681276 ! N-glycan processing GO:0006491 20 10 0,000 0,05029757 0,09673537 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05029757 0,09665811 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05029757 0,09658097 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05029757 0,09650395 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05029757 0,09642705 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05029757 0,09635028 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05029757 0,09627363 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05029757 0,0961971 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05029757 0,09612069 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05029757 0,09604441 ! androgen metabolic process GO:0008209 17 10 0,000 0,05029757 0,09596824 ! phospholipid efflux GO:0033700 16 10 0,000 0,05029757 0,0958922 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05029757 0,09581627 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05029757 0,09574047 ! pathogenesis GO:0009405 13 10 0,000 0,05029757 0,09566478 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05029757 0,09558922 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05029757 0,09551377 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05029757 0,09543845 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05029757 0,09536324 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05029757 0,09528815 ! endoderm development GO:0007492 16 10 0,000 0,05029757 0,09521318 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05029757 0,09513833 ! arginine catabolic process GO:0006527 13 10 0,000 0,05029757 0,09506359 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05029757 0,09498897 ! proline metabolic process GO:0006560 13 10 0,000 0,05029757 0,09491447 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05029757 0,09484009 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05029757 0,09476582 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05029757 0,09469167 ! V(D)J recombination GO:0033151 28 10 0,000 0,05029757 0,09461763 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05029757 0,09454371 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05029757 0,09446991 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05029757 0,09439622 ! B cell proliferation GO:0042100 18 10 0,000 0,05029757 0,09432264 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05029757 0,09424918 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05029757 0,09417584 ! multicellular organism growth GO:0035264 18 10 0,000 0,05029757 0,09410261 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05029757 0,09402949 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05029757 0,09395648 ! epithelial cell development GO:0002064 20 10 0,000 0,05029757 0,09388359 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05029757 0,09381082 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05029757 0,09373815 ! macroautophagy GO:0016236 17 10 0,000 0,05029757 0,0936656 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05029757 0,09359316 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05029757 0,09352083 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05029757 0,09344861 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05029757 0,09337651 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05029757 0,09330451 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05029757 0,09323263 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05029757 0,09316086 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05029757 0,09308919 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05029757 0,09301764 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05029757 0,0929462 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05029757 0,09287487 ! response to dsRNA GO:0043331 20 10 0,000 0,05029757 0,09280364 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05029757 0,09273253 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05029757 0,09266152 ! melanosome localization GO:0032400 16 10 0,000 0,05029757 0,09259063 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05029757 0,09251984 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05029757 0,09244916 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05029757 0,09237859 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05029757 0,09230812 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05029757 0,09223777 ! mRNA cleavage GO:0006379 17 10 0,000 0,05029757 0,09216752 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05029757 0,09209738 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05029757 0,09202734 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05029757 0,09195741 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05029757 0,09188759 ! salivary gland development GO:0007431 27 10 0,000 0,05029757 0,09181787 ! prophase GO:0051324 15 10 0,000 0,05029757 0,09174826 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05029757 0,09167875 ! apical protein localization GO:0045176 15 10 0,000 0,05029757 0,09160935 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05029757 0,09154005 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05029757 0,09147086 ! midbrain development GO:0030901 13 10 0,000 0,05029757 0,09140178 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05029757 0,09133279 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05029757 0,09126392 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05029757 0,09119514 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05029757 0,09112647 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05029757 0,0910579 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05029757 0,09098944 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05029757 0,09092108 ! detection of calcium ion GO:0005513 23 10 0,000 0,05029757 0,09085282 ! oocyte development GO:0048599 17 10 0,000 0,05029757 0,09078466 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05029757 0,09071661 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05029757 0,09064865 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05029757 0,0905808 ! activation of innate immune response GO:0002218 12 10 0,000 0,05029757 0,09051305 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05029757 0,0904454 ! response to nicotine GO:0035094 20 10 0,000 0,05029757 0,09037786 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05029757 0,09031041 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05029757 0,09024307 ! reproductive structure development GO:0048608 113 71 1,000 0,05191724 0,09307964 ! regulation of blood pressure GO:0008217 125 73 1,000 0,05454413 0,09771643 ! axon guidance GO:0007411 139 73 1,000 0,05454413 0,09764373 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05518693 0,098721 ! respiratory burst GO:0045730 17 11 0,000 0,05518693 0,09864766 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05518693 0,09857442 ! neuron fate specification GO:0048665 17 11 0,000 0,05518693 0,09850129 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05518693 0,09842828 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05518693 0,09835537 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05518693 0,09828256 ! thyroid gland development GO:0030878 26 11 0,000 0,05518693 0,09820987 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05518693 0,09813728 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05518693 0,0980648 ! response to pain GO:0048265 24 11 0,000 0,05518693 0,09799243 ! T cell proliferation GO:0042098 26 11 0,000 0,05518693 0,09792017 ! bone resorption GO:0045453 16 11 0,000 0,05518693 0,09784801 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05518693 0,09777595 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05518693 0,09770401 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05518693 0,09763217 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05518693 0,09756043 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05518693 0,0974888 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05518693 0,09741727 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05518693 0,09734585 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05518693 0,09727454 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,05518693 0,09720333 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05518693 0,09713222 ! UV protection GO:0009650 19 11 0,000 0,05518693 0,09706122 ! adult heart development GO:0007512 14 11 0,000 0,05518693 0,09699032 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05518693 0,09691952 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05518693 0,09684883 ! temperature homeostasis GO:0001659 17 11 0,000 0,05518693 0,09677824 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05518693 0,09670775 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05518693 0,09663737 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05518693 0,09656709 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05518693 0,09649691 ! regulation of organ growth GO:0046620 13 11 0,000 0,05518693 0,09642683 ! pigment granule localization GO:0051875 20 11 0,000 0,05518693 0,09635685 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05518693 0,09628698 ! vasoconstriction GO:0042310 18 11 0,000 0,05518693 0,09621721 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05518693 0,09614753 ! embryonic axis specification GO:0000578 18 11 0,000 0,05518693 0,09607796 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05518693 0,09600849 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05518693 0,09593912 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05518693 0,09586985 ! DNA methylation GO:0006306 19 11 0,000 0,05518693 0,09580068 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05518693 0,09573161 ! zymogen activation GO:0031638 15 11 0,000 0,05518693 0,09566264 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05518693 0,09559377 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05518693 0,095525 ! nucleosome positioning GO:0016584 15 11 0,000 0,05518693 0,09545632 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05518693 0,09538775 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05518693 0,09531927 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05518693 0,09525089 ! acid secretion GO:0046717 18 11 0,000 0,05518693 0,09518261 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05518693 0,09511443 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05518693 0,09504635 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05518693 0,09497836 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05518693 0,09491047 ! oocyte differentiation GO:0009994 18 11 0,000 0,05518693 0,09484267 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05518693 0,09477498 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05518693 0,09470738 ! cholesterol efflux GO:0033344 19 11 0,000 0,05518693 0,09463988 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05518693 0,09457247 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05518693 0,09450516 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05518693 0,09443794 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,05518693 0,09437082 ! embryonic gut development GO:0048566 15 11 0,000 0,05518693 0,0943038 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05518693 0,09423687 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05518693 0,09417003 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05518693 0,09410329 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05518693 0,09403665 ! defense response to fungus GO:0050832 13 11 0,000 0,05518693 0,0939701 ! developmental induction GO:0031128 19 11 0,000 0,05518693 0,09390364 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05518693 0,09383728 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05518693 0,09377101 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05518693 0,09370483 ! nucleus localization GO:0051647 19 11 0,000 0,05518693 0,09363875 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05518693 0,09357276 ! organelle localization GO:0051640 136 74 1,000 0,05587491 0,09467257 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,05721706 0,09687843 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,05857042 0,09910016 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,05993484 0,10133747 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06005127 0,10146304 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06005127 0,10139183 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06005127 0,10132073 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06005127 0,10124973 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06005127 0,10117883 ! cartilage condensation GO:0001502 20 12 0,000 0,06005127 0,10110802 ! mating GO:0007618 17 12 0,000 0,06005127 0,10103732 ! protein complex disassembly GO:0043241 27 12 0,000 0,06005127 0,10096671 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,06005127 0,1008962 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06005127 0,10082579 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06005127 0,10075548 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06005127 0,10068527 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06005127 0,10061516 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06005127 0,10054514 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06005127 0,10047522 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06005127 0,10040539 ! drug transport GO:0015893 16 12 0,000 0,06005127 0,10033567 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06005127 0,10026604 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06005127 0,10019651 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06005127 0,10012707 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06005127 0,10005773 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06005127 0,09998849 ! forebrain cell migration GO:0021885 21 12 0,000 0,06005127 0,09991934 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06005127 0,09985029 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06005127 0,09978133 ! entry into host cell GO:0030260 32 12 0,000 0,06005127 0,09971247 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06005127 0,0996437 ! monoamine transport GO:0015844 18 12 0,000 0,06005127 0,09957503 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06005127 0,09950645 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06005127 0,09943797 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06005127 0,09936958 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06005127 0,09930128 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06005127 0,09923308 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06005127 0,09916497 ! protein homotetramerization GO:0051289 21 12 0,000 0,06005127 0,09909696 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06005127 0,09902904 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06005127 0,09896121 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06005127 0,09889347 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06005127 0,09882583 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06005127 0,09875828 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06005127 0,09869082 ! cranial nerve development GO:0021545 20 12 0,000 0,06005127 0,09862346 ! fucose catabolic process GO:0019317 22 12 0,000 0,06005127 0,09855618 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06005127 0,098489 ! histone methylation GO:0016571 26 12 0,000 0,06005127 0,09842191 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06005127 0,09835491 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06005127 0,098288 ! gland morphogenesis GO:0022612 29 12 0,000 0,06005127 0,09822119 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06005127 0,09815446 ! T cell homeostasis GO:0043029 25 12 0,000 0,06005127 0,09808782 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06005127 0,09802128 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06005127 0,09795482 ! spleen development GO:0048536 22 12 0,000 0,06005127 0,09788846 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06005127 0,09782218 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06005127 0,097756 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06005127 0,0976899 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06005127 0,09762389 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06005127 0,09755798 ! response to cold GO:0009409 17 12 0,000 0,06005127 0,09749215 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06005127 0,09742641 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06005127 0,09736076 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,06131017 0,09933486 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,06269626 0,10151225 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,06269626 0,10144398 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,06269626 0,10137581 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,06409298 0,10356461 ! protein import into nucleus GO:0006606 158 80 1,000 0,06409298 0,1034951 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06489074 0,10471302 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06489074 0,10464284 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06489074 0,10457275 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06489074 0,10450275 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06489074 0,10443285 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06489074 0,10436304 ! lipid localization GO:0010876 28 13 0,000 0,06489074 0,10429333 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06489074 0,10422371 ! organelle fusion GO:0048284 32 13 0,000 0,06489074 0,10415418 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06489074 0,10408474 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06489074 0,1040154 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06489074 0,10394615 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06489074 0,10387699 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06489074 0,10380792 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06489074 0,10373895 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06489074 0,10367006 ! methionine metabolic process GO:0006555 27 13 0,000 0,06489074 0,10360127 ! plasma membrane organization GO:0007009 24 13 0,000 0,06489074 0,10353257 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06489074 0,10346396 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06489074 0,10339544 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06489074 0,10332701 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06489074 0,10325867 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06489074 0,10319042 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06489074 0,10312227 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06489074 0,1030542 ! exocrine system development GO:0035272 32 13 0,000 0,06489074 0,10298622 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06489074 0,10291833 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06489074 0,10285054 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06489074 0,10278283 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06489074 0,10271521 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06489074 0,10264767 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06489074 0,10258023 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06489074 0,10251288 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06489074 0,10244561 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06489074 0,10237843 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06489074 0,10231135 ! ribosome assembly GO:0042255 17 13 0,000 0,06489074 0,10224434 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06489074 0,10217743 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06489074 0,1021106 ! chromatin silencing GO:0006342 26 13 0,000 0,06489074 0,10204386 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06489074 0,10197721 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06489074 0,10191065 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06489074 0,10184417 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06489074 0,10177778 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06489074 0,10171147 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06489074 0,10164526 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06489074 0,10157912 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06489074 0,10151308 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06489074 0,10144712 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06489074 0,10138124 ! embryonic placenta development GO:0001892 23 13 0,000 0,06489074 0,10131545 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06489074 0,10124975 ! insulin secretion GO:0030073 23 13 0,000 0,06489074 0,10118413 ! actin filament polymerization GO:0030041 24 13 0,000 0,06489074 0,1011186 ! acrosome reaction GO:0007340 18 13 0,000 0,06489074 0,10105315 ! T cell activation GO:0042110 168 81 1,000 0,06550017 0,10193622 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,06550017 0,10187033 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 1,000 0,06550017 0,10180452 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,06691769 0,10394058 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,06691769 0,10387352 ! response to nutrient GO:0007584 125 82 1,000 0,06691769 0,10380655 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,06691769 0,10373966 ! regulation of lyase activity GO:0051339 160 83 1,000 0,0683454 0,10588476 ! rRNA transcription GO:0009303 25 14 0,000 0,06970544 0,10792233 ! lactation GO:0007595 26 14 0,000 0,06970544 0,10785292 ! reproductive cellular process GO:0048610 20 14 0,000 0,06970544 0,10778361 ! tRNA modification GO:0006400 20 14 0,000 0,06970544 0,10771439 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06970544 0,10764525 ! regulation of S phase GO:0033261 23 14 0,000 0,06970544 0,1075762 ! water transport GO:0006833 21 14 0,000 0,06970544 0,10750724 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06970544 0,10743837 ! non-recombinational repair GO:0000726 25 14 0,000 0,06970544 0,10736959 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06970544 0,10730089 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06970544 0,10723229 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06970544 0,10716377 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06970544 0,10709534 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06970544 0,10702699 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06970544 0,10695874 ! palate development GO:0060021 31 14 0,000 0,06970544 0,10689057 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,06970544 0,10682248 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06970544 0,10675449 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06970544 0,10668658 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06970544 0,10661875 ! arginine metabolic process GO:0006525 17 14 0,000 0,06970544 0,10655101 ! regulation of heart rate GO:0002027 24 14 0,000 0,06970544 0,10648336 ! organic alcohol transport GO:0015850 29 14 0,000 0,06970544 0,1064158 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06970544 0,10634832 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06970544 0,10628092 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 26 14 0,000 0,06970544 0,10621361 ! L-amino acid transport GO:0015807 30 14 0,000 0,06970544 0,10614639 ! bone mineralization GO:0030282 17 14 0,000 0,06970544 0,10607925 ! stem cell development GO:0048864 43 14 0,000 0,06970544 0,1060122 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06970544 0,10594523 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06970544 0,10587834 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06970544 0,10581154 ! cerebellum development GO:0021549 21 14 0,000 0,06970544 0,10574483 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06970544 0,1056782 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06970544 0,10561165 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06970544 0,10554518 ! cofactor transport GO:0051181 26 14 0,000 0,06970544 0,1054788 ! NADP metabolic process GO:0006739 24 14 0,000 0,06970544 0,10541251 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06970544 0,10534629 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06970544 0,10528016 ! intestinal absorption GO:0050892 25 14 0,000 0,06970544 0,10521411 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06970544 0,10514815 ! oxygen transport GO:0015671 21 14 0,000 0,06970544 0,10508227 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06970544 0,10501647 ! male genitalia development GO:0030539 24 14 0,000 0,06970544 0,10495075 ! regulation of axon extension GO:0030516 37 14 0,000 0,06970544 0,10488511 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06970544 0,10481956 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,06978316 0,10487089 ! negative regulation of transport GO:0051051 153 84 1,000 0,06978316 0,10480542 ! regulation of ligase activity GO:0051340 142 84 1,000 0,06978316 0,10474004 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,06978316 0,10467474 ! response to unfolded protein GO:0006986 131 85 1,000 0,07123083 0,10677968 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,07123083 0,10671319 GO:0002696|positive regulation of leukocyte activation, ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,07415535 0,11102538 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,07415535 0,11095633 ! regulation of protein transport GO:0051223 154 87 1,000 0,07415535 0,11088737 GO:0070201|regulation of establishment of protein localization, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07449552 0,11132684 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07449552 0,11125774 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07449552 0,11118872 ! superoxide anion generation GO:0042554 20 15 0,000 0,07449552 0,11111979 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07449552 0,11105094 ! copper ion transport GO:0006825 20 15 0,000 0,07449552 0,11098218 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07449552 0,1109135 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07449552 0,11084491 ! sulfate transport GO:0008272 23 15 0,000 0,07449552 0,1107764 ! response to cAMP GO:0051591 22 15 0,000 0,07449552 0,11070798 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07449552 0,11063964 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07449552 0,11057139 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07449552 0,11050322 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07449552 0,11043513 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07449552 0,11036713 ! pituitary gland development GO:0021983 29 15 0,000 0,07449552 0,11029921 ! vesicle coating GO:0006901 33 15 0,000 0,07449552 0,11023138 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07449552 0,11016363 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07449552 0,11009596 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07449552 0,11002837 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07449552 0,10996087 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07449552 0,10989345 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07449552 0,10982612 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07449552 0,10975886 ! histone deacetylation GO:0016575 20 15 0,000 0,07449552 0,10969169 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07449552 0,1096246 ! tissue regeneration GO:0042246 26 15 0,000 0,07449552 0,10955759 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07449552 0,10949067 ! water homeostasis GO:0030104 27 15 0,000 0,07449552 0,10942382 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07449552 0,10935706 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07449552 0,10929038 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07449552 0,10922378 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07449552 0,10915726 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,07449552 0,10909082 ! detection of bacterium GO:0016045 18 15 0,000 0,07449552 0,10902446 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07449552 0,10895819 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07449552 0,10889199 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07449552 0,10882588 ! peptide hormone processing GO:0016486 23 15 0,000 0,07449552 0,10875984 ! regulation of neurological system process GO:0031644 148 88 1,000 0,07563193 0,11035198 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,07711786 0,11245187 ! ossification GO:0001503 188 90 1,000 0,07861303 0,11456266 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,07861303 0,11449331 ! sex differentiation GO:0007548 145 90 1,000 0,07861303 0,11442404 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07926109 0,11529757 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,07926109 0,1152279 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07926109 0,11515832 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07926109 0,11508882 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,07926109 0,11501941 ! bone remodeling GO:0046849 27 16 0,000 0,07926109 0,11495008 ! filopodium assembly GO:0046847 32 16 0,000 0,07926109 0,11488083 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07926109 0,11481167 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07926109 0,11474259 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07926109 0,11467359 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07926109 0,11460468 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07926109 0,11453585 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,07926109 0,1144671 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07926109 0,11439843 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07926109 0,11432985 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07926109 0,11426134 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07926109 0,11419292 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07926109 0,11412459 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07926109 0,11405633 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07926109 0,11398815 ! response to osmotic stress GO:0006970 25 16 0,000 0,07926109 0,11392006 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,07926109 0,11385205 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,07926109 0,11378412 ! fructose metabolic process GO:0006000 25 16 0,000 0,07926109 0,11371627 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07926109 0,1136485 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07926109 0,11358081 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07926109 0,1135132 ! negative regulation of immune response GO:0050777 35 16 0,000 0,07926109 0,11344568 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07926109 0,11337823 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07926109 0,11331086 ! neuron recognition GO:0008038 35 16 0,000 0,07926109 0,11324358 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07926109 0,11317637 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07926109 0,11310924 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07926109 0,11304219 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07926109 0,11297523 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07926109 0,11290834 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07926109 0,11284153 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07926109 0,1127748 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07926109 0,11270815 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07926109 0,11264157 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07926109 0,11257508 ! defense response to virus GO:0051607 37 16 0,000 0,07926109 0,11250866 ! bone development GO:0060348 189 91 1,000 0,08011729 0,11365695 ! sterol metabolic process GO:0016125 152 91 1,000 0,08011729 0,11358998 ! response to protein stimulus GO:0051789 149 91 1,000 0,08011729 0,11352308 ! vitamin metabolic process GO:0006766 139 92 1,000 0,08163051 0,11559918 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,08315257 0,11768534 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,08315257 0,11761616 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,08315257 0,11754705 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,08400228 0,1186785 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08400228 0,11860885 ! metencephalon development GO:0022037 30 17 0,000 0,08400228 0,11853929 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08400228 0,1184698 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08400228 0,1184004 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08400228 0,11833108 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08400228 0,11826184 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08400228 0,11819268 ! glial cell development GO:0021782 27 17 0,000 0,08400228 0,1181236 ! limbic system development GO:0021761 36 17 0,000 0,08400228 0,1180546 ! adult walking behavior GO:0007628 33 17 0,000 0,08400228 0,11798569 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,08400228 0,11791685 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08400228 0,1178481 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08400228 0,11777942 ! myoblast differentiation GO:0045445 45 17 0,000 0,08400228 0,11771082 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08400228 0,11764231 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,08400228 0,11757387 ! glycine metabolic process GO:0006544 28 17 0,000 0,08400228 0,11750551 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08400228 0,11743724 ! NAD metabolic process GO:0019674 29 17 0,000 0,08400228 0,11736904 ! membrane budding GO:0006900 37 17 0,000 0,08400228 0,11730092 ! DNA integration GO:0015074 29 17 0,000 0,08400228 0,11723288 ! regulation of protein binding GO:0043393 33 17 0,000 0,08400228 0,11716492 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08400228 0,11709704 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08400228 0,11702923 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08400228 0,11696151 ! genitalia development GO:0048806 30 17 0,000 0,08400228 0,11689386 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,08400228 0,11682629 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,08400228 0,1167588 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,08400228 0,11669139 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08400228 0,11662405 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08400228 0,1165568 ! steroid catabolic process GO:0006706 31 17 0,000 0,08400228 0,11648962 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08400228 0,11642251 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,08400228 0,11635549 ! gas transport GO:0015669 25 17 0,000 0,08400228 0,11628854 ! organic cation transport GO:0015695 31 17 0,000 0,08400228 0,11622167 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08400228 0,11615488 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08400228 0,11608816 ! microspike assembly GO:0030035 36 17 0,000 0,08400228 0,11602152 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,08400228 0,11595495 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,08468333 0,11682803 ! female pregnancy GO:0007565 164 94 1,000 0,08468333 0,11676108 ! transcription initiation GO:0006352 153 94 1,000 0,08468333 0,11669421 ! positive regulation of immune response GO:0050778 156 96 1,000 0,08777045 0,12087905 ! detection of stimulus GO:0051606 151 96 1,000 0,08777045 0,1208099 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08871921 0,12204598 ! neuron maturation GO:0042551 42 18 0,000 0,08871921 0,12197624 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08871921 0,12190658 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08871921 0,121837 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,08871921 0,1217675 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08871921 0,12169807 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08871921 0,12162873 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08871921 0,12155947 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08871921 0,12149028 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08871921 0,12142117 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08871921 0,12135214 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08871921 0,12128319 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08871921 0,12121432 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08871921 0,12114553 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08871921 0,12107681 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08871921 0,12100818 ! response to retinoic acid GO:0032526 26 18 0,000 0,08871921 0,12093962 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,08871921 0,12087113 ! response to fungus GO:0009620 21 18 0,000 0,08871921 0,12080273 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08871921 0,1207344 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08871921 0,12066615 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08871921 0,12059798 ! vitamin transport GO:0051180 27 18 0,000 0,08871921 0,12052988 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08871921 0,12046186 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08871921 0,12039392 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08871921 0,12032605 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08871921 0,12025827 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08871921 0,12019055 ! nerve development GO:0021675 28 18 0,000 0,08871921 0,12012292 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08871921 0,12005535 ! regulation of protein localization GO:0032880 176 97 1,000 0,08932655 0,12080927 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,09089085 0,12285584 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,09246322 0,12491101 ! protein secretion GO:0009306 39 19 0,000 0,09341201 0,12612194 ! positive regulation of translation GO:0045727 30 19 0,000 0,09341201 0,1260512 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09341201 0,12598055 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09341201 0,12590997 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09341201 0,12583947 ! skin development GO:0043588 36 19 0,000 0,09341201 0,12576905 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09341201 0,12569871 ! lipid phosphorylation GO:0046834 35 19 0,000 0,09341201 0,12562845 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09341201 0,12555826 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09341201 0,12548816 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09341201 0,12541813 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09341201 0,12534818 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09341201 0,12527831 ! cerebral cortex development GO:0021987 36 19 0,000 0,09341201 0,12520852 ! pigmentation during development GO:0048066 41 19 0,000 0,09341201 0,1251388 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09341201 0,12506917 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09341201 0,12499961 ! heme metabolic process GO:0042168 36 19 0,000 0,09341201 0,12493012 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09341201 0,12486072 ! peptide cross-linking GO:0018149 37 19 0,000 0,09341201 0,12479139 ! protein export from nucleus GO:0006611 36 19 0,000 0,09341201 0,12472214 ! heart process GO:0003015 30 19 0,000 0,09341201 0,12465296 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09341201 0,12458387 GO:0006692|prostanoid metabolic process, ! cellular pigmentation GO:0033059 36 19 0,000 0,09341201 0,12451484 ! G1 phase GO:0051318 40 19 0,000 0,09341201 0,1244459 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09341201 0,12437703 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09341201 0,12430824 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,09341201 0,12423952 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09341201 0,12417088 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09341201 0,12410232 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09341201 0,12403383 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09341201 0,12396541 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09341201 0,12389707 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09341201 0,12382881 ! cilium assembly GO:0042384 37 19 0,000 0,09341201 0,12376062 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09341201 0,12369251 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0980808 0,1298033 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0980808 0,12973194 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0980808 0,12966066 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0980808 0,12958945 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0980808 0,12951833 ! response to vitamin GO:0033273 31 20 0,000 0,0980808 0,12944728 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0980808 0,12937631 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0980808 0,12930542 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0980808 0,12923461 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0980808 0,12916387 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0980808 0,12909321 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0980808 0,12902263 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0980808 0,12895213 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0980808 0,1288817 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0980808 0,12881135 ! body fluid secretion GO:0007589 31 20 0,000 0,0980808 0,12874108 ! peptide secretion GO:0002790 35 20 0,000 0,0980808 0,12867088 ! stem cell differentiation GO:0048863 53 20 0,000 0,0980808 0,12860076 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0980808 0,12853072 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0980808 0,12846075 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0980808 0,12839086 ! sensory perception of pain GO:0019233 30 20 0,000 0,0980808 0,12832104 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0980808 0,1282513 ! diencephalon development GO:0021536 34 20 0,000 0,0980808 0,12818164 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0980808 0,12811205 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0980808 0,12804254 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0980808 0,1279731 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0980808 0,12790374 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0980808 0,12783445 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0980808 0,12776524 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0980808 0,1276961 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0980808 0,12762704 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0980808 0,12755805 ! regulation of glucose import GO:0046324 29 20 0,000 0,0980808 0,12748914 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0980808 0,1274203 ! actin filament-based movement GO:0030048 43 20 0,000 0,0980808 0,12735153 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0980808 0,12728284 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0980808 0,12721423 ! negative regulation of translation GO:0017148 29 20 0,000 0,0980808 0,12714569 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0980808 0,12707722 ! regulation of cell killing GO:0031341 42 21 0,000 0,10272569 0,13302369 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10272569 0,13295213 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10272569 0,13288065 ! hormone secretion GO:0046879 38 21 0,000 0,10272569 0,13280925 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10272569 0,13273792 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10272569 0,13266668 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10272569 0,1325955 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10272569 0,13252441 ! axis specification GO:0009798 38 21 0,000 0,10272569 0,13245338 ! ovarian follicle development GO:0001541 35 21 0,000 0,10272569 0,13238244 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,10272569 0,13231157 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10272569 0,13224078 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10272569 0,13217006 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10272569 0,13209942 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10272569 0,13202885 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10272569 0,13195836 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10272569 0,13188795 ! cytolysis GO:0019835 24 21 0,000 0,10272569 0,13181761 ! vasodilation GO:0042311 39 21 0,000 0,10272569 0,13174734 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10272569 0,13167715 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10272569 0,13160704 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10272569 0,131537 ! oogenesis GO:0048477 36 21 0,000 0,10272569 0,13146703 ! DNA modification GO:0006304 34 21 0,000 0,10272569 0,13139714 ! collagen fibril organization GO:0030199 59 21 0,000 0,10272569 0,13132732 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10272569 0,13125758 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10272569 0,13118791 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10272569 0,13111831 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,10272569 0,13104879 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10272569 0,13097934 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10272569 0,13090997 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10272569 0,13084066 ! collagen catabolic process GO:0030574 28 21 0,000 0,10272569 0,13077144 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10272569 0,13070228 ! gut development GO:0048565 39 21 0,000 0,10272569 0,1306332 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,10734682 0,13643764 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,10734682 0,1363656 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10734682 0,13629364 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10734682 0,13622176 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10734682 0,13614995 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10734682 0,13607822 ! regeneration GO:0031099 41 22 0,000 0,10734682 0,13600656 ! keratinization GO:0031424 28 22 0,000 0,10734682 0,13593498 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,10734682 0,13586347 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10734682 0,13579204 ! sensory perception of taste GO:0050909 28 22 0,000 0,10734682 0,13572068 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10734682 0,1356494 ! vacuolar transport GO:0007034 36 22 0,000 0,10734682 0,13557819 ! lysosome organization GO:0007040 41 22 0,000 0,10734682 0,13550706 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10734682 0,135436 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,10734682 0,13536502 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,10734682 0,13529411 ! fucose metabolic process GO:0006004 39 22 0,000 0,10734682 0,13522327 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10734682 0,13515251 ! ureteric bud development GO:0001657 43 22 0,000 0,10734682 0,13508183 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10734682 0,13501121 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,10734682 0,13494068 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,10734682 0,13487021 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,10734682 0,13479982 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10734682 0,1347295 ! sarcomere organization GO:0045214 30 22 0,000 0,10734682 0,13465926 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,10734682 0,13458908 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10734682 0,13451899 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10734682 0,13444896 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,1119443 0,14013423 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1119443 0,14006136 ! viral genome replication GO:0019079 41 23 0,000 0,1119443 0,13998856 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1119443 0,13991584 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1119443 0,1398432 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1119443 0,13977063 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1119443 0,13969813 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,1119443 0,13962571 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1119443 0,13955337 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,1119443 0,1394811 ! peroxisome organization GO:0007031 37 23 0,000 0,1119443 0,1394089 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1119443 0,13933678 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1119443 0,13926474 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,1119443 0,13919276 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1119443 0,13912087 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,1119443 0,13904904 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1119443 0,13897729 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1119443 0,13890562 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1119443 0,13883402 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1119443 0,13876249 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1119443 0,13869104 ! platelet activation GO:0030168 37 23 0,000 0,1119443 0,13861966 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1119443 0,13854835 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1119443 0,13847712 ! hormone transport GO:0009914 40 23 0,000 0,1119443 0,13840596 ! cell-cell recognition GO:0009988 25 23 0,000 0,1119443 0,13833487 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1119443 0,13826386 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1119443 0,13819292 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1119443 0,13812205 GO:0006099|tricarboxylic acid cycle, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,11651826 0,14369192 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,11651826 0,14361831 ! vesicle docking GO:0048278 47 24 0,000 0,11651826 0,14354477 ! spinal cord development GO:0021510 47 24 0,000 0,11651826 0,14347131 ! vacuole organization GO:0007033 43 24 0,000 0,11651826 0,14339792 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11651826 0,14332461 ! digestive system process GO:0022600 39 24 0,000 0,11651826 0,14325137 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,11651826 0,14317821 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,11651826 0,14310512 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,11651826 0,14303211 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,11651826 0,14295917 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,11651826 0,14288631 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,11651826 0,14281352 ! pallium development GO:0021543 49 24 0,000 0,11651826 0,1427408 ! pentose metabolic process GO:0019321 35 24 0,000 0,11651826 0,14266816 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,11651826 0,14259559 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,11651826 0,1425231 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11651826 0,14245068 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11651826 0,14237833 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11651826 0,14230606 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,11651826 0,14223386 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11651826 0,14216173 ! regulation of amine transport GO:0051952 40 24 0,000 0,11651826 0,14208968 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,12106881 0,14756411 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12106881 0,1474894 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,12106881 0,14741476 ! phototransduction GO:0007602 33 25 0,000 0,12106881 0,14734019 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12106881 0,1472657 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,12106881 0,14719129 ! chromosome condensation GO:0030261 45 25 0,000 0,12106881 0,14711695 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12106881 0,14704268 ! neural crest cell development GO:0014032 54 25 0,000 0,12106881 0,14696849 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12106881 0,14689438 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12106881 0,14682034 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12106881 0,14674638 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12106881 0,14667249 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,12106881 0,14659867 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12106881 0,14652493 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,12106881 0,14645126 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12106881 0,14637767 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12106881 0,14630415 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12106881 0,1462307 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12106881 0,14615733 ! telomere organization GO:0032200 43 25 0,000 0,12106881 0,14608403 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12106881 0,14601081 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,12106881 0,14593765 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,12559607 0,15131905 ! embryonic pattern specification GO:0009880 44 26 0,000 0,12559607 0,15124332 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,12559607 0,15116766 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,12559607 0,15109207 ! initiation of viral infection GO:0019059 57 26 0,000 0,12559607 0,15101656 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12559607 0,15094113 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,12559607 0,15086577 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,12559607 0,15079049 ! tube lumen formation GO:0035148 50 26 0,000 0,12559607 0,15071528 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12559607 0,15064015 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,12559607 0,1505651 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,12559607 0,15049011 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,12559607 0,1504152 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,12559607 0,15034037 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12559607 0,15026561 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,12559607 0,15019093 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12559607 0,15011632 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,12559607 0,15004178 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,12559607 0,14996732 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,12559607 0,14989293 ! leukocyte proliferation GO:0070661 52 26 0,000 0,12559607 0,14981861 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12559607 0,14974437 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,12559607 0,14967021 ! neuron fate commitment GO:0048663 48 27 0,000 0,13010016 0,15496089 ! iron ion transport GO:0006826 59 27 0,000 0,13010016 0,15488421 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13010016 0,15480761 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13010016 0,15473109 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13010016 0,15465464 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13010016 0,15457827 ! autophagy GO:0006914 41 27 0,000 0,13010016 0,15450197 ! male gonad development GO:0008584 44 27 0,000 0,13010016 0,15442575 ! primary neural tube formation GO:0014020 51 27 0,000 0,13010016 0,1543496 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13010016 0,15427353 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13010016 0,15419753 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13010016 0,15412161 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,13010016 0,15404576 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13010016 0,15396999 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,1345812 0,15919487 ! circadian rhythm GO:0007623 50 28 0,000 0,1345812 0,15911664 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,1345812 0,15903849 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,1345812 0,15896042 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,1345812 0,15888242 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,1345812 0,1588045 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,1345812 0,15872665 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,1345812 0,15864888 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,1345812 0,15857119 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,1345812 0,15849357 ! synaptogenesis GO:0007416 42 28 0,000 0,1345812 0,15841603 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,1345812 0,15833857 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,1345812 0,15826118 ! translational initiation GO:0006413 65 29 0,000 0,13903931 0,16342383 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,13903931 0,16334403 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,13903931 0,16326431 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,13903931 0,16318467 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,13903931 0,16310511 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,13903931 0,16302562 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,13903931 0,16294621 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,13903931 0,16286688 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,13903931 0,16278763 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,13903931 0,16270845 ! detection of light stimulus GO:0009583 38 29 0,000 0,13903931 0,16262935 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,13903931 0,16255033 ! tissue homeostasis GO:0001894 48 29 0,000 0,13903931 0,16247138 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,13903931 0,16239251 ! zinc ion transport GO:0006829 45 30 0,000 0,14347459 0,16749145 ! membrane docking GO:0022406 61 30 0,000 0,14347459 0,16741022 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14347459 0,16732907 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14347459 0,167248 ! acute-phase response GO:0006953 49 30 0,000 0,14347459 0,16716701 ! myofibril assembly GO:0030239 47 30 0,000 0,14347459 0,16708609 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,14347459 0,16700526 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14347459 0,1669245 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,14347459 0,16684382 ! phospholipid transport GO:0015914 51 30 0,000 0,14347459 0,16676322 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14347459 0,1666827 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,14347459 0,16660225 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14347459 0,16652189 ! eye morphogenesis GO:0048592 60 30 0,000 0,14347459 0,1664416 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,14788718 0,17147786 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,14788718 0,17139525 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,14788718 0,17131273 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,14788718 0,17123029 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,14788718 0,17114793 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,14788718 0,17106565 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,14788718 0,17098345 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,14788718 0,17090132 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,14788718 0,17081927 ! ovulation cycle process GO:0022602 49 31 0,000 0,14788718 0,17073731 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,14788718 0,17065542 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,14788718 0,17057361 ! peptide transport GO:0015833 55 31 0,000 0,14788718 0,17049188 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,14788718 0,17041022 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,14788718 0,17032865 ! mesoderm formation GO:0001707 69 31 0,000 0,14788718 0,17024715 ! natural killer cell activation GO:0030101 45 31 0,000 0,14788718 0,17016573 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,14788718 0,17008439 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,14788718 0,17000313 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,14788718 0,16992194 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15227718 0,17488252 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15227718 0,17479909 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15227718 0,17471573 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15227718 0,17463245 ! cholesterol transport GO:0030301 56 32 0,000 0,15227718 0,17454925 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15227718 0,17446614 ! spliceosome assembly GO:0000245 67 32 0,000 0,15227718 0,1743831 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15227718 0,17430014 ! metanephros development GO:0001656 74 32 0,000 0,15227718 0,17421725 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15227718 0,17413445 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15227718 0,17405173 ! muscle cell development GO:0055001 49 32 0,000 0,15227718 0,17396908 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15227718 0,17388651 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15227718 0,17380403 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,15227718 0,17372161 ! ovulation cycle GO:0042698 51 32 0,000 0,15227718 0,17363928 ! BMP signaling pathway GO:0030509 64 32 0,000 0,15227718 0,17355703 ! hindbrain development GO:0030902 61 32 0,000 0,15227718 0,17347485 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15227718 0,17339275 ! gene silencing GO:0016458 65 32 0,000 0,15227718 0,17331073 ! post-embryonic development GO:0009791 69 33 0,000 0,1566447 0,17819724 ! protein targeting to membrane GO:0006612 68 33 0,000 0,1566447 0,17811302 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,1566447 0,17802889 ! ceramide metabolic process GO:0006672 64 33 0,000 0,1566447 0,17794483 ! formation of primary germ layer GO:0001704 72 33 0,000 0,1566447 0,17786086 ! cell fate specification GO:0001708 52 33 0,000 0,1566447 0,17777696 ! sterol transport GO:0015918 57 33 0,000 0,1566447 0,17769314 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,1566447 0,1776094 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,1566447 0,17752574 ! adult locomotory behavior GO:0008344 59 33 0,000 0,1566447 0,17744216 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,1566447 0,17735866 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,16098987 0,18219268 ! glial cell differentiation GO:0010001 63 34 0,000 0,16098987 0,18210702 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,16098987 0,18202144 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,16098987 0,18193595 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,16098987 0,18185053 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16098987 0,1817652 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16098987 0,18167994 ! mismatch repair GO:0006298 46 34 0,000 0,16098987 0,18159476 ! spermatid development GO:0007286 63 34 0,000 0,16098987 0,18150967 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,16098987 0,18142465 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16098987 0,18133972 ! regulation of muscle development GO:0048634 70 35 0,000 0,1653128 0,18612194 ! negative regulation of secretion GO:0051048 63 35 0,000 0,1653128 0,18603489 ! odontogenesis GO:0042476 66 35 0,000 0,1653128 0,18594791 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,1653128 0,18586102 ! female gonad development GO:0008585 58 35 0,000 0,1653128 0,18577421 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,1653128 0,18568748 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,1653128 0,18560084 ! cytokine production GO:0001816 59 35 0,000 0,1653128 0,18551427 ! neural tube formation GO:0001841 67 35 0,000 0,1653128 0,18542778 ! vesicle localization GO:0051648 64 35 0,000 0,1653128 0,18534137 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,16961359 0,19007466 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,16961359 0,18998617 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,16961359 0,18989777 ! positive regulation of cell development GO:0010720 80 36 0,000 0,16961359 0,18980944 ! regulation of proteolysis GO:0030162 72 36 0,000 0,16961359 0,1897212 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,16961359 0,18963304 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,16961359 0,18954496 ! aerobic respiration GO:0009060 55 36 0,000 0,16961359 0,18945697 ! embryonic organ development GO:0048568 57 36 0,000 0,16961359 0,18936905 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,17389237 0,19405614 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,17389237 0,19396618 ! actomyosin structure organization GO:0031032 62 37 0,000 0,17389237 0,19387629 ! organic anion transport GO:0015711 68 37 0,000 0,17389237 0,19378649 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17389237 0,19369678 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,17389237 0,19360715 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17389237 0,1935176 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,17389237 0,19342813 ! pigment metabolic process GO:0042440 80 37 0,000 0,17389237 0,19333874 ! spermatid differentiation GO:0048515 66 37 0,000 0,17389237 0,19324944 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,17814924 0,19788877 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,17814924 0,19779745 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,17814924 0,19770621 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,17814924 0,19761506 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 0,000 0,17814924 0,197524 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,17814924 0,19743301 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,17814924 0,19734211 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,17814924 0,1972513 ! glucan metabolic process GO:0044042 62 38 0,000 0,17814924 0,19716057 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,18238432 0,20175479 ! organic ether metabolic process GO:0018904 55 39 0,000 0,18238432 0,20166207 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,18238432 0,20156944 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18238432 0,20147689 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,18238432 0,20138443 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18238432 0,20129205 ! RNA modification GO:0009451 57 39 0,000 0,18238432 0,20119976 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,18659771 0,20575348 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,18659771 0,20565923 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18659771 0,20556506 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,18659771 0,20547098 ! mesenchymal cell development GO:0014031 87 40 0,000 0,18659771 0,20537699 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,18659771 0,20528308 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,19078953 0,20979872 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,19078953 0,20970288 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,19078953 0,20960713 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,19078953 0,20951146 ! gliogenesis GO:0042063 88 41 0,000 0,19078953 0,20941588 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,19078953 0,20932039 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,19078953 0,20922498 ! female gamete generation GO:0007292 61 41 0,000 0,19078953 0,20912966 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,19078953 0,20903443 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,19495989 0,21350637 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,19495989 0,21340923 ! regulation of tube size GO:0035150 71 42 0,000 0,19495989 0,21331218 GO:0050880|regulation of blood vessel size, ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,19495989 0,21321522 ! neuron migration GO:0001764 79 42 0,000 0,19495989 0,21311835 ! regulation of protein secretion GO:0050708 71 42 0,000 0,19495989 0,21302156 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,19495989 0,21292487 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,19910889 0,21735752 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,19910889 0,21725895 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,19910889 0,21716046 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,19910889 0,21706207 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,19910889 0,21696376 ! neural tube development GO:0021915 77 43 0,000 0,19910889 0,21686554 ! striated muscle contraction GO:0006941 77 43 0,000 0,19910889 0,21676741 ! phagocytosis GO:0006909 90 43 0,000 0,19910889 0,21666937 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,19910889 0,21657142 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,20323664 0,2209613 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,20323664 0,2208615 ! male sex differentiation GO:0046661 76 44 0,000 0,20323664 0,22076179 ! biopolymer methylation GO:0043414 84 44 0,000 0,20323664 0,22066217 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,20323664 0,22056263 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,20734326 0,22491789 ! glycolysis GO:0006096 65 45 0,000 0,20734326 0,22481653 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,20734326 0,22471526 ! leukocyte migration GO:0050900 68 45 0,000 0,20734326 0,22461409 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,20734326 0,224513 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,20734326 0,224412 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,20734326 0,2243111 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,20734326 0,22421028 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,20734326 0,22410956 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,20734326 0,22400893 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,21142885 0,22832038 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,21142885 0,22821795 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,21142885 0,22811561 ! positive regulation of defense response GO:0031349 76 47 0,000 0,21549351 0,23239686 ! response to calcium ion GO:0051592 81 47 0,000 0,21549351 0,23229274 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,21549351 0,23218871 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,21549351 0,23208478 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,21549351 0,23198094 ! methylation GO:0032259 90 47 0,000 0,21549351 0,23187719 ! protein homooligomerization GO:0051260 76 47 0,000 0,21549351 0,23177353 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,21953736 0,23601738 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,21953736 0,23591196 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,21953736 0,23580665 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,21953736 0,23570142 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,21953736 0,23559629 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,2235605 0,23980676 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,2235605 0,23969989 ! peptide metabolic process GO:0006518 76 49 0,000 0,2235605 0,23959312 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2235605 0,23948645 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,2235605 0,23937987 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,2235605 0,23927338 ! regulation of ossification GO:0030278 117 50 0,000 0,22756303 0,24344893 ! inner ear development GO:0048839 79 50 0,000 0,22756303 0,24334073 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,22756303 0,24323263 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,22756303 0,24312462 ! viral infectious cycle GO:0019058 99 51 0,000 0,23154506 0,24726916 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,23154506 0,24715946 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,23154506 0,24704985 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,23154506 0,24694034 ! excretion GO:0007588 83 51 0,000 0,23154506 0,24683093 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,23154506 0,24672162 ! chromatin remodeling GO:0006338 109 51 0,000 0,23154506 0,2466124 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,23154506 0,24650328 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,23154506 0,24639426 ! vesicle organization GO:0016050 107 51 0,000 0,23154506 0,24628533 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,23154506 0,2461765 ! membrane fusion GO:0006944 110 52 0,000 0,2355067 0,25027787 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,2355067 0,25016738 ! amino acid activation GO:0043038 92 52 0,000 0,2355067 0,25005698 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,2355067 0,24994667 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,23944804 0,25401763 ! RNA catabolic process GO:0006401 93 53 0,000 0,23944804 0,25390568 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,23944804 0,25379382 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,23944804 0,25368207 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,23944804 0,25357041 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,23944804 0,25345886 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,24336919 0,25749616 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,24336919 0,25738298 ! cell recognition GO:0008037 85 54 0,000 0,24336919 0,25726989 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,24336919 0,25715691 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,24336919 0,25704402 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,24336919 0,25693123 ! chloride transport GO:0006821 90 55 0,000 0,24727026 0,26093519 ! glucose catabolic process GO:0006007 82 55 0,000 0,24727026 0,2608208 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,24727026 0,2607065 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,24727026 0,26059231 ! gastrulation GO:0007369 112 55 0,000 0,24727026 0,26047821 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,24727026 0,26036422 ! RNA elongation GO:0006354 79 55 0,000 0,24727026 0,26025032 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,24727026 0,26013653 ! regulation of actin filament length GO:0030832 105 56 0,000 0,25115134 0,26410408 ! sensory perception of smell GO:0007608 80 56 0,000 0,25115134 0,2639887 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,25115134 0,26387342 ! proton transport GO:0015992 94 56 0,000 0,25115134 0,26375824 ! hydrogen transport GO:0006818 97 58 0,000 0,25885396 0,2717289 ! regulation of endocytosis GO:0030100 91 58 0,000 0,25885396 0,27161039 ! adult behavior GO:0030534 99 58 0,000 0,25885396 0,27149199 ! positive regulation of secretion GO:0051047 95 59 0,000 0,2626757 0,27538027 ! regulation of cellular component size GO:0032535 109 59 0,000 0,2626757 0,27526034 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,2626757 0,2751405 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,26647786 0,27900162 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,26647786 0,27888026 ! camera-type eye development GO:0043010 116 60 0,000 0,26647786 0,27875901 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,26647786 0,27863786 ! kidney development GO:0001822 122 60 0,000 0,26647786 0,27851682 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,27026053 0,28234774 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,27026053 0,28222519 ! mesoderm development GO:0007498 119 61 0,000 0,27026053 0,28210275 ! tRNA processing GO:0008033 89 61 0,000 0,27026053 0,28198042 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,27026053 0,28185819 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,27402383 0,28565916 ! gonad development GO:0008406 98 62 0,000 0,27402383 0,28553544 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,27776784 0,28931144 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,27776784 0,28918625 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,27776784 0,28906117 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,28149267 0,29281079 ! cell redox homeostasis GO:0045454 102 64 0,000 0,28149267 0,29268425 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,28149267 0,29255783 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,28149267 0,29243151 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,28519841 0,29615338 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,28519841 0,29602562 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,28519841 0,29589796 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,28519841 0,29577042 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,28888516 0,29946476 ! extracellular matrix organization GO:0030198 133 66 0,000 0,28888516 0,29933579 ! secondary metabolic process GO:0019748 116 66 0,000 0,28888516 0,29920693 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,29255302 0,30287546 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,29255302 0,30274519 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,29255302 0,30261503 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,29255302 0,30248499 ! hexose catabolic process GO:0019320 104 67 0,000 0,29255302 0,30235506 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,29255302 0,30222523 ! amino acid transport GO:0006865 125 68 0,000 0,29620208 0,30586361 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,29620208 0,30573239 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,29620208 0,30560129 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,29983244 0,30921425 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,29983244 0,30908177 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,29983244 0,3089494 ! antigen processing and presentation GO:0019882 104 69 0,000 0,29983244 0,30881715 ! appendage morphogenesis GO:0035107 135 70 0,000 0,3034442 0,31240339 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,30703744 0,31596753 ! appendage development GO:0048736 136 71 0,000 0,30703744 0,31583244 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,30703744 0,31569747 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,30703744 0,31556261 ! regulation of immune effector process GO:0002697 137 71 0,000 0,30703744 0,31542787 ! acute inflammatory response GO:0002526 113 72 0,000 0,31061226 0,31896419 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,31061226 0,31882812 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,31061226 0,31869216 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,31061226 0,31855631 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,31061226 0,31842058 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,31416876 0,32192932 ! fertilization GO:0009566 90 73 0,000 0,31416876 0,32179227 ! transition metal ion transport GO:0000041 126 74 0,000 0,31770704 0,32527793 ! neurotransmitter transport GO:0006836 123 74 0,000 0,31770704 0,32513957 ! exocytosis GO:0006887 133 74 0,000 0,31770704 0,32500133 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,31770704 0,32486321 ! eye development GO:0001654 143 74 0,000 0,31770704 0,3247252 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,32122717 0,32818368 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,32122717 0,32804439 ! rhythmic process GO:0048511 128 75 0,000 0,32122717 0,32790521 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,32472926 0,33133953 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,32472926 0,33119907 ! defense response to bacterium GO:0042742 89 76 0,000 0,32472926 0,33105873 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,32472926 0,33091851 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,3282134 0,33432745 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,3282134 0,33418597 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,3282134 0,3340446 ! blood coagulation GO:0007596 146 78 0,000 0,33167967 0,33742972 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,33167967 0,33728711 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,33167967 0,33714461 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,33512818 0,34050608 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,33512818 0,34036235 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,33512818 0,34021873 ! response to metal ion GO:0010038 140 80 0,000 0,338559 0,34355671 ! muscle cell differentiation GO:0042692 159 80 0,000 0,338559 0,34341187 ! inorganic anion transport GO:0015698 138 80 0,000 0,338559 0,34326716 ! digestion GO:0007586 112 81 0,000 0,34197224 0,34658181 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,34197224 0,34643588 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,34197224 0,34629007 ! hemostasis GO:0007599 158 84 0,000 0,3521073 0,3564031 ! nucleosome assembly GO:0006334 122 85 0,000 0,35545107 0,35963636 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,35545107 0,35948519 ! amine biosynthetic process GO:0009309 138 86 0,000 0,35877769 0,36269711 ! response to inorganic substance GO:0010035 153 86 0,000 0,35877769 0,36254478 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,35877769 0,36239258 ! chromatin assembly GO:0031497 124 86 0,000 0,35877769 0,3622405 ! tube morphogenesis GO:0035239 176 86 0,000 0,35877769 0,36208856 ! alcohol catabolic process GO:0046164 130 86 0,000 0,35877769 0,36193674 ! amine transport GO:0015837 155 86 0,000 0,35877769 0,36178505 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,36208725 0,36496939 ! cellular respiration GO:0045333 135 88 0,000 0,36537984 0,36813396 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,36537984 0,36797987 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,36537984 0,3678259 ! cellular defense response GO:0006968 114 89 0,000 0,36865555 0,37096832 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,37191445 0,37409121 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,37515664 0,37719468 ! regulation of defense response GO:0031347 149 92 0,000 0,3783822 0,38027886 ! nucleosome organization GO:0034728 138 92 0,000 0,3783822 0,38012008 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,3783822 0,37996143 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,38159122 0,38302398 GO:0010498|proteasomal protein catabolic process, ! forebrain development GO:0030900 188 95 0,000 0,38795996 0,38925424 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,38795996 0,38909198 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,39111985 0,39209765 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,39426353 0,39508457 ! protein ubiquitination GO:0016567 217 97 0,000 0,39426353 0,39492009 ! hormone metabolic process GO:0042445 157 97 0,000 0,39426353 0,39475575 ! response to virus GO:0009615 160 98 0,000 0,39739108 0,39772169 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,39739108 0,39755632 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,40050259 0,40050259