pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6634-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 2,638E-09 6,443E-06 ! spindle organization GO:0007051 50 32 5,000 9,603E-09 1,173E-05 ! natural killer cell mediated immunity GO:0002228 19 10 3,000 1,087E-07 8,852E-05 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 28 12 3,000 2,543E-07 1,553E-04 ! cell killing GO:0001906 32 15 3,000 6,933E-07 3,387E-04 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 2,000 1,106E-06 4,502E-04 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 3,000 2,415E-06 8,427E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 2,415E-06 7,374E-04 ! positive regulation of intracellular transport GO:0032388 42 22 3,000 3,618E-06 9,822E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 6,126E-06 1,496E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 1,303E-05 2,894E-03 ! regulation of fat cell differentiation GO:0045598 18 10 2,000 1,303E-05 2,653E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 2,372E-05 4,458E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 2,372E-05 4,14E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of caspase activity GO:0043281 136 74 4,000 3,078E-05 5,014E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 3,437E-05 5,248E-03 ! regulation of endopeptidase activity GO:0052548 141 77 4,000 3,732E-05 5,363E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 3,897E-05 5,289E-03 ! actin cytoskeleton reorganization GO:0031532 38 15 2,000 4,854E-05 6,242E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 2,000 4,854E-05 5,93E-03 ! regulation of peptidase activity GO:0052547 150 82 4,000 5,054E-05 5,879E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 5,953E-05 6,611E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis by intracellular signals GO:0008629 95 45 3,000 6,757E-05 7,177E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 7,203E-05 7,332E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 7,373E-05 7,205E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 7,373E-05 6,928E-03 ! regulation of gene-specific transcription GO:0032583 102 46 3,000 7,373E-05 6,671E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 8,028E-05 7,005E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 8,613E-05 7,256E-03 ! negative regulation of protein catabolic process GO:0042177 42 18 2,000 8,613E-05 7,014E-03 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 9,465E-05 7,459E-03 ! regulation of membrane potential GO:0042391 179 94 4,000 9,703E-05 7,408E-03 ! regulation of action potential GO:0001508 102 50 3,000 1,025E-04 7,588E-03 ! activation of caspase activity GO:0006919 95 50 3,000 1,025E-04 7,365E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 1,126E-04 7,86E-03 ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,195E-04 8,108E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 1,289E-04 8,508E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,389E-04 8,929E-03 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 1,389E-04 8,701E-03 ! response to UV GO:0009411 120 55 3,000 1,49E-04 9,098E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 1,598E-04 9,523E-03 ! microtubule-based transport GO:0010970 59 22 2,000 1,603E-04 9,321E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 1,603E-04 9,105E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,712E-04 9,507E-03 ! positive regulation of caspase activity GO:0043280 108 57 3,000 1,712E-04 9,296E-03 GO:0010952|positive regulation of peptidase activity, ! regulation of intracellular transport GO:0032386 108 57 3,000 1,712E-04 9,094E-03 ! aging GO:0007568 112 58 3,000 1,832E-04 9,524E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 1,832E-04 9,325E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 2,000 1,836E-04 9,156E-03 ! fatty acid transport GO:0015908 47 23 2,000 1,836E-04 8,973E-03 ! nuclear export GO:0051168 110 59 3,000 1,958E-04 9,38E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 2,091E-04 9,825E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 2,091E-04 9,64E-03 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 2,091E-04 9,461E-03 ! negative regulation of catabolic process GO:0009895 52 24 2,000 2,091E-04 9,289E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,306E-04 0,01005958 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 2,306E-04 9,883E-03 ! Notch receptor processing GO:0007220 11 5 1,000 2,306E-04 9,713E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,306E-04 9,548E-03 ! lymph vessel development GO:0001945 10 5 1,000 2,306E-04 9,389E-03 ! anagen GO:0042640 7 5 1,000 2,306E-04 9,235E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,306E-04 9,086E-03 ! microvillus organization GO:0032528 8 5 1,000 2,306E-04 8,942E-03 GO:0030033|microvillus assembly, ! polyol biosynthetic process GO:0046173 6 5 1,000 2,306E-04 8,802E-03 ! sister chromatid cohesion GO:0007062 15 5 1,000 2,306E-04 8,667E-03 ! positive regulation of filopodium assembly GO:0051491 16 5 1,000 2,306E-04 8,535E-03 GO:0051489|regulation of filopodium assembly, ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,306E-04 8,408E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,306E-04 8,284E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,306E-04 8,164E-03 ! decidualization GO:0046697 11 5 1,000 2,306E-04 8,048E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,306E-04 7,934E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 2,306E-04 7,824E-03 GO:0051930|regulation of sensory perception of pain, ! protein insertion into membrane GO:0051205 17 5 1,000 2,306E-04 7,717E-03 ! receptor biosynthetic process GO:0032800 7 5 1,000 2,306E-04 7,613E-03 ! stem cell division GO:0017145 11 5 1,000 2,306E-04 7,511E-03 GO:0048103|somatic stem cell division, ! negative regulation of DNA replication GO:0008156 45 25 2,000 2,368E-04 7,612E-03 ! receptor metabolic process GO:0043112 53 25 2,000 2,368E-04 7,513E-03 ! protein tetramerization GO:0051262 57 25 2,000 2,368E-04 7,417E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 2,667E-04 8,249E-03 GO:0045936|negative regulation of phosphate metabolic process, ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 2,683E-04 8,192E-03 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 2,683E-04 8,091E-03 ! lymphocyte mediated immunity GO:0002449 122 65 3,000 2,848E-04 8,485E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 2,848E-04 8,382E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 2,99E-04 8,696E-03 ! response to toxin GO:0009636 49 27 2,000 2,99E-04 8,594E-03 ! regulation of chromosome organization GO:0033044 49 27 2,000 2,99E-04 8,494E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 2,99E-04 8,396E-03 ! negative regulation of cell growth GO:0030308 142 67 3,000 3,2E-04 8,884E-03 ! chromosome segregation GO:0007059 127 67 3,000 3,2E-04 8,784E-03 ! spliceosomal snRNP biogenesis GO:0000387 40 28 2,000 3,337E-04 9,058E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 3,337E-04 8,959E-03 ! regulation of smooth muscle cell differentiation GO:0051150 12 6 1,000 3,448E-04 9,156E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 3,448E-04 9,057E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 3,448E-04 8,961E-03 GO:0051653|spindle localization, ! hair follicle maturation GO:0048820 8 6 1,000 3,448E-04 8,866E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 3,448E-04 8,774E-03 ! cytoplasmic microtubule organization GO:0031122 18 6 1,000 3,448E-04 8,684E-03 ! maternal placenta development GO:0001893 12 6 1,000 3,448E-04 8,595E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 3,448E-04 8,508E-03 ! negative regulation of cell size GO:0045792 144 69 3,000 3,582E-04 8,751E-03 ! cellular iron ion homeostasis GO:0006879 57 29 2,000 3,709E-04 8,971E-03 ! cell cycle checkpoint GO:0000075 145 71 3,000 3,996E-04 9,571E-03 ! negative regulation of transcription regulator activity GO:0090048 57 30 2,000 4,106E-04 9,74E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 2,000 4,106E-04 9,646E-03 ! iron ion homeostasis GO:0055072 60 31 2,000 4,53E-04 0,01054043 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 4,53E-04 0,010441 ! ensheathment of neurons GO:0007272 64 31 2,000 4,53E-04 0,01034342 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 4,53E-04 0,01024765 ! regulation of helicase activity GO:0051095 16 7 1,000 4,812E-04 0,01078426 ! sleep GO:0030431 16 7 1,000 4,812E-04 0,01068622 ! prostate gland development GO:0030850 14 7 1,000 4,812E-04 0,01058995 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 4,812E-04 0,0104954 ! mRNA stabilization GO:0048255 18 7 1,000 4,812E-04 0,01040252 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 4,812E-04 0,01031127 ! lipoprotein transport GO:0042953 14 7 1,000 4,812E-04 0,0102216 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 4,812E-04 0,01013349 ! male sex determination GO:0030238 15 7 1,000 4,812E-04 0,01004688 ! monocyte differentiation GO:0030224 16 7 1,000 4,812E-04 9,962E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 4,812E-04 9,878E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 4,812E-04 9,796E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 4,812E-04 9,715E-03 ! lymphocyte activation during immune response GO:0002285 11 7 1,000 4,812E-04 9,635E-03 ! regulation of transcription factor activity GO:0051090 137 75 3,000 4,924E-04 9,781E-03 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 3,000 4,924E-04 9,702E-03 ! regulation of catabolic process GO:0009894 173 77 3,000 5,442E-04 0,01063525 ! positive regulation of gene-specific transcription GO:0043193 70 33 2,000 5,46E-04 0,01058615 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 6,395E-04 0,01230177 ! male meiosis GO:0007140 9 8 1,000 6,395E-04 0,01220566 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 6,395E-04 0,01211104 ! T-helper 1 type immune response GO:0042088 12 8 1,000 6,395E-04 0,01201788 ! endothelial cell differentiation GO:0045446 17 8 1,000 6,395E-04 0,01192614 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 6,395E-04 0,01183579 ! ER overload response GO:0006983 13 8 1,000 6,395E-04 0,0117468 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 6,395E-04 0,01165914 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 6,395E-04 0,01157277 ! regulation of vascular permeability GO:0043114 12 8 1,000 6,395E-04 0,01148768 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 6,395E-04 0,01140383 ! response to tumor cell GO:0002347 16 8 1,000 6,395E-04 0,01132119 ! regulation of respiratory burst GO:0060263 12 8 1,000 6,395E-04 0,01123974 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 6,395E-04 0,01115946 ! positive regulation of smooth muscle contraction GO:0045987 15 8 1,000 6,395E-04 0,01108032 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 6,395E-04 0,01100229 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 6,395E-04 0,01092535 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 6,503E-04 0,01103314 ! placenta development GO:0001890 53 35 2,000 6,503E-04 0,01095705 ! meiosis GO:0007126 143 81 3,000 6,591E-04 0,01102786 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 3,000 6,903E-04 0,01147146 ! meiotic cell cycle GO:0051321 144 82 3,000 6,903E-04 0,01139395 ! negative regulation of DNA binding GO:0043392 67 36 2,000 7,069E-04 0,01159106 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 7,666E-04 0,01248535 ! negative regulation of cell activation GO:0050866 69 37 2,000 7,666E-04 0,01240267 ! negative regulation of growth GO:0045926 168 85 3,000 7,901E-04 0,01269945 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 7,901E-04 0,01261645 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 8,196E-04 0,01300203 ! induction of positive chemotaxis GO:0050930 17 9 1,000 8,196E-04 0,01291814 ! regulation of glycolysis GO:0006110 20 9 1,000 8,196E-04 0,01283534 ! middle ear morphogenesis GO:0042474 14 9 1,000 8,196E-04 0,01275358 ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 8,196E-04 0,01267286 ! receptor clustering GO:0043113 20 9 1,000 8,196E-04 0,01259316 ! response to amine stimulus GO:0014075 13 9 1,000 8,196E-04 0,01251445 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 8,196E-04 0,01243672 ! regulation of telomere maintenance GO:0032204 17 9 1,000 8,196E-04 0,01235995 ! DNA integrity checkpoint GO:0031570 82 38 2,000 8,294E-04 0,01243025 ! regulation of protein stability GO:0031647 77 38 2,000 8,294E-04 0,01235446 ! mitochondrion organization GO:0007005 159 87 3,000 8,621E-04 0,0127649 ! negative regulation of binding GO:0051100 71 39 2,000 8,953E-04 0,01317595 ! carbohydrate homeostasis GO:0033500 59 39 2,000 8,953E-04 0,01309705 GO:0042593|glucose homeostasis, ! regulation of DNA binding GO:0051101 167 89 3,000 9,386E-04 0,01364942 ! learning GO:0007612 82 40 2,000 9,645E-04 0,01394191 ! nucleus organization GO:0006997 73 40 2,000 9,645E-04 0,0138599 ! regulation of action potential in neuron GO:0019228 80 40 2,000 9,645E-04 0,01377885 ! regulation of developmental growth GO:0048638 16 10 1,000 1,021E-03 0,01450541 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,021E-03 0,01442156 ! lung alveolus development GO:0048286 26 10 1,000 1,021E-03 0,01433868 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,021E-03 0,01425675 ! motor axon guidance GO:0008045 22 10 1,000 1,021E-03 0,01417574 ! regulation of bone resorption GO:0045124 25 10 1,000 1,021E-03 0,01409565 ! protein heterooligomerization GO:0051291 17 10 1,000 1,021E-03 0,01401646 ! DNA ligation GO:0006266 18 10 1,000 1,021E-03 0,01393816 ! leukocyte activation during immune response GO:0002366 15 10 1,000 1,021E-03 0,01386073 GO:0002263|cell activation during immune response, ! protein sumoylation GO:0016925 17 10 1,000 1,021E-03 0,01378415 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 1,021E-03 0,01370841 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,021E-03 0,0136335 GO:0043470|regulation of carbohydrate catabolic process, ! blastocyst formation GO:0001825 18 10 1,000 1,021E-03 0,01355941 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,021E-03 0,01348611 ! RNA export from nucleus GO:0006405 61 41 2,000 1,037E-03 0,01361938 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,106E-03 0,01444591 ! alcohol biosynthetic process GO:0046165 65 42 2,000 1,113E-03 0,01445968 ! regulation of T cell differentiation GO:0045580 78 42 2,000 1,113E-03 0,01438317 ! glucose transport GO:0015758 66 43 2,000 1,192E-03 0,01532615 ! monocarboxylic acid transport GO:0015718 93 43 2,000 1,192E-03 0,01524591 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 2,000 1,192E-03 0,0151665 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,192E-03 0,01508792 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,244E-03 0,01566838 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,244E-03 0,01558803 ! keratinocyte proliferation GO:0043616 19 11 1,000 1,244E-03 0,0155085 ! blood vessel remodeling GO:0001974 30 11 1,000 1,244E-03 0,01542978 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,244E-03 0,01535185 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,244E-03 0,0152747 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,244E-03 0,01519833 ! regulation of intracellular pH GO:0051453 21 11 1,000 1,244E-03 0,01512271 ! positive regulation of muscle contraction GO:0045933 19 11 1,000 1,244E-03 0,01504785 ! nitric oxide metabolic process GO:0046209 17 11 1,000 1,244E-03 0,01497372 GO:0006809|nitric oxide biosynthetic process, ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,244E-03 0,01490032 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 1,244E-03 0,01482764 ! sequestering of metal ion GO:0051238 15 11 1,000 1,244E-03 0,01475566 ! regulation of embryonic development GO:0045995 35 11 1,000 1,244E-03 0,01468438 ! hexose transport GO:0008645 68 44 2,000 1,275E-03 0,01497112 GO:0015749|monosaccharide transport, ! leukocyte differentiation GO:0002521 232 98 3,000 1,343E-03 0,01569484 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 1,343E-03 0,0156201 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,361E-03 0,01575654 ! B cell differentiation GO:0030183 124 45 2,000 1,361E-03 0,01568221 ! maintenance of location in cell GO:0051651 101 45 2,000 1,361E-03 0,01560859 ! cell growth GO:0016049 90 46 2,000 1,451E-03 0,01656081 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,488E-03 0,01691166 ! virus-host interaction GO:0019048 30 12 1,000 1,488E-03 0,01683337 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 1,488E-03 0,01675579 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,488E-03 0,01667893 ! regulation of cell projection assembly GO:0060491 33 12 1,000 1,488E-03 0,01660277 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,488E-03 0,01652731 ! focal adhesion formation GO:0048041 37 12 1,000 1,488E-03 0,01645252 ! mitotic spindle organization GO:0007052 23 12 1,000 1,488E-03 0,01637841 ! histone acetylation GO:0016573 27 12 1,000 1,488E-03 0,01630497 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,488E-03 0,01623218 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,488E-03 0,01616003 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,488E-03 0,01608853 ! localization within membrane GO:0051668 26 12 1,000 1,488E-03 0,01601765 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,641E-03 0,01758576 ! cellular component disassembly GO:0022411 89 48 2,000 1,641E-03 0,01750897 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 1,742E-03 0,0185042 ! endocrine pancreas development GO:0031018 25 13 1,000 1,753E-03 0,01854307 ! indolalkylamine metabolic process GO:0006586 19 13 1,000 1,753E-03 0,01846314 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 1,000 1,753E-03 0,0183839 ! membrane protein proteolysis GO:0033619 33 13 1,000 1,753E-03 0,01830534 GO:0006509|membrane protein ectodomain proteolysis, ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,753E-03 0,01822745 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,753E-03 0,01815021 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,753E-03 0,01807363 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 1,753E-03 0,01799769 ! negative regulation of immune system process GO:0002683 101 51 2,000 1,955E-03 0,01998619 ! embryo implantation GO:0007566 30 14 1,000 2,039E-03 0,02075621 ! regulation of cellular pH GO:0030641 27 14 1,000 2,039E-03 0,02067008 ! response to gamma radiation GO:0010332 30 14 1,000 2,039E-03 0,02058467 ! regulation of RNA stability GO:0043487 33 14 1,000 2,039E-03 0,02049996 ! regulation of muscle contraction GO:0006937 94 54 2,000 2,304E-03 0,02307122 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,345E-03 0,02338624 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,345E-03 0,02329117 ! phospholipid catabolic process GO:0009395 27 15 1,000 2,345E-03 0,02319687 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 1,000 2,345E-03 0,02310334 ! glycoprotein catabolic process GO:0006516 33 15 1,000 2,345E-03 0,02301055 ! G1/S transition checkpoint GO:0031575 37 15 1,000 2,345E-03 0,02291851 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 2,345E-03 0,0228272 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,345E-03 0,02273662 ! muscle maintenance GO:0046716 26 15 1,000 2,345E-03 0,02264675 ! dopamine metabolic process GO:0042417 35 15 1,000 2,345E-03 0,02255759 ! positive regulation of calcium ion transport GO:0051928 21 15 1,000 2,345E-03 0,02246913 ! regulation of protein catabolic process GO:0042176 126 56 2,000 2,557E-03 0,02440193 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,672E-03 0,02539832 ! positive regulation of ion transport GO:0043270 23 16 1,000 2,672E-03 0,02529988 ! startle response GO:0001964 28 16 1,000 2,672E-03 0,0252022 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 2,672E-03 0,02510527 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! intermediate filament-based process GO:0045103 36 16 1,000 2,672E-03 0,02500908 ! axon cargo transport GO:0008088 46 16 1,000 2,672E-03 0,02491362 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,672E-03 0,02481889 ! DNA replication initiation GO:0006270 28 16 1,000 2,672E-03 0,02472488 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 2,672E-03 0,02463158 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,672E-03 0,02453898 ! heart morphogenesis GO:0003007 105 57 2,000 2,69E-03 0,02460938 ! maintenance of location GO:0051235 124 58 2,000 2,826E-03 0,02576377 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,019E-03 0,02741346 ! signal complex assembly GO:0007172 47 17 1,000 3,019E-03 0,02731193 ! endothelial cell migration GO:0043542 31 17 1,000 3,019E-03 0,02721115 ! regulation of muscle cell differentiation GO:0051147 36 17 1,000 3,019E-03 0,02711111 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 3,019E-03 0,0270118 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,019E-03 0,02691322 ! regulation of striated muscle contraction GO:0006942 23 17 1,000 3,019E-03 0,02681535 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 3,019E-03 0,02671819 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 3,019E-03 0,02662174 ! DNA catabolic process GO:0006308 94 60 2,000 3,112E-03 0,02735111 ! heart looping GO:0001947 34 18 1,000 3,385E-03 0,02964049 ! cell-substrate junction assembly GO:0007044 56 18 1,000 3,385E-03 0,02953463 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 3,385E-03 0,02942953 ! long-chain fatty acid transport GO:0015909 32 18 1,000 3,385E-03 0,02932517 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 3,385E-03 0,02922154 ! regulation of homeostatic process GO:0032844 148 62 2,000 3,416E-03 0,02938187 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 3,736E-03 0,03202804 ! inositol metabolic process GO:0006020 33 19 1,000 3,771E-03 0,03221437 ! memory GO:0007613 34 19 1,000 3,771E-03 0,03210212 ! regulation of postsynaptic membrane potential GO:0060078 38 19 1,000 3,771E-03 0,03199066 ! neuromuscular junction development GO:0007528 43 19 1,000 3,771E-03 0,03187996 ! response to lipopolysaccharide GO:0032496 34 19 1,000 3,771E-03 0,03177003 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 3,771E-03 0,03166086 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 3,771E-03 0,03155243 ! visual learning GO:0008542 38 19 1,000 3,771E-03 0,03144474 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 4,075E-03 0,03386042 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 4,177E-03 0,0345918 ! protein amino acid acetylation GO:0006473 41 20 1,000 4,177E-03 0,03447493 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 4,177E-03 0,03435885 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 4,177E-03 0,03424356 ! pancreas development GO:0031016 40 20 1,000 4,177E-03 0,03412903 ! actin filament bundle formation GO:0051017 47 20 1,000 4,177E-03 0,03401527 ! fatty acid beta-oxidation GO:0006635 36 20 1,000 4,177E-03 0,03390226 ! vitamin A metabolic process GO:0006776 35 21 1,000 4,602E-03 0,03722857 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 4,602E-03 0,0371057 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 4,617E-03 0,03709995 ! lung development GO:0030324 165 69 2,000 4,617E-03 0,03697831 ! developmental maturation GO:0021700 128 69 2,000 4,617E-03 0,03685747 ! negative regulation of kinase activity GO:0033673 145 70 2,000 4,806E-03 0,03824751 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 5,001E-03 0,0396654 ! glutamate signaling pathway GO:0007215 48 22 1,000 5,046E-03 0,03989702 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 5,046E-03 0,03976832 ! cellular response to starvation GO:0009267 37 22 1,000 5,046E-03 0,03964045 ! cell aging GO:0007569 48 22 1,000 5,046E-03 0,0395134 ! positive regulation of locomotion GO:0040017 44 22 1,000 5,046E-03 0,03938716 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of B cell activation GO:0050871 42 22 1,000 5,046E-03 0,03926172 ! response to cytokine stimulus GO:0034097 69 22 1,000 5,046E-03 0,03913708 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 5,046E-03 0,03901323 ! protein stabilization GO:0050821 41 22 1,000 5,046E-03 0,03889016 ! carbohydrate transport GO:0008643 114 72 2,000 5,2E-03 0,03994762 ! respiratory tube development GO:0030323 171 72 2,000 5,2E-03 0,03982239 ! actin filament organization GO:0007015 167 72 2,000 5,2E-03 0,03969794 ! B cell activation GO:0042113 179 72 2,000 5,2E-03 0,03957427 ! positive regulation of DNA replication GO:0045740 44 23 1,000 5,509E-03 0,0417999 ! gluconeogenesis GO:0006094 38 23 1,000 5,509E-03 0,04167048 ! regulation of chemotaxis GO:0050920 45 23 1,000 5,509E-03 0,04154187 ! visual behavior GO:0007632 46 23 1,000 5,509E-03 0,04141405 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 5,509E-03 0,04128701 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 1,000 5,509E-03 0,04116075 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 5,509E-03 0,04103526 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 5,509E-03 0,04091054 ! negative regulation of transferase activity GO:0051348 155 74 2,000 5,612E-03 0,04154773 ! respiratory system development GO:0060541 175 74 2,000 5,612E-03 0,04142221 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 5,991E-03 0,0440865 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 5,991E-03 0,04395411 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 5,991E-03 0,04382251 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! sex determination GO:0007530 48 24 1,000 5,991E-03 0,0436917 ! membrane depolarization GO:0051899 45 24 1,000 5,991E-03 0,04356166 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 5,991E-03 0,0434324 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 5,991E-03 0,0433039 ! cell-matrix adhesion GO:0007160 181 76 2,000 6,044E-03 0,04355396 ! learning or memory GO:0007611 161 76 2,000 6,044E-03 0,04342586 ! lymphocyte differentiation GO:0030098 193 76 2,000 6,044E-03 0,04329851 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 6,492E-03 0,04637185 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 6,492E-03 0,04623665 ! myeloid leukocyte differentiation GO:0002573 46 25 1,000 6,492E-03 0,04610224 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 6,492E-03 0,04596861 ! regulation of transmembrane transport GO:0034762 39 25 1,000 6,492E-03 0,04583576 ! vasculogenesis GO:0001570 49 25 1,000 6,492E-03 0,04570367 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 6,492E-03 0,04557233 ! regulation of behavior GO:0050795 48 25 1,000 6,492E-03 0,04544175 ! interaction with host GO:0051701 66 25 1,000 6,492E-03 0,04531192 ! protein oligomerization GO:0051259 149 79 2,000 6,727E-03 0,04682185 ! myelination GO:0042552 50 26 1,000 7,01E-03 0,04865473 ! pyruvate metabolic process GO:0006090 43 26 1,000 7,01E-03 0,0485169 ! molting cycle process GO:0022404 52 26 1,000 7,01E-03 0,04837985 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 7,01E-03 0,04824357 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 7,01E-03 0,04810805 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 7,01E-03 0,0479733 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 7,01E-03 0,04783929 ! negative regulation of cell development GO:0010721 83 26 1,000 7,01E-03 0,04770603 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 1,000 7,01E-03 0,04757352 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 50 26 1,000 7,01E-03 0,04744174 ! response to hypoxia GO:0001666 178 81 2,000 7,207E-03 0,04863926 ! positive regulation of cell projection organization GO:0031346 66 27 1,000 7,547E-03 0,05079379 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 7,547E-03 0,05065424 ! mitochondrial membrane organization GO:0007006 60 27 1,000 7,547E-03 0,05051546 ! response to starvation GO:0042594 47 27 1,000 7,547E-03 0,05037744 ! cellular response to nutrient levels GO:0031669 45 27 1,000 7,547E-03 0,05024018 ! fat-soluble vitamin metabolic process GO:0006775 42 27 1,000 7,547E-03 0,05010365 ! response to drug GO:0042493 149 83 2,000 7,707E-03 0,05102648 ! response to oxygen levels GO:0070482 183 83 2,000 7,707E-03 0,05088857 ! cellular lipid catabolic process GO:0044242 150 83 2,000 7,707E-03 0,05075141 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 8,102E-03 0,05320901 ! protein amino acid acylation GO:0043543 59 28 1,000 8,102E-03 0,05306636 ! fat cell differentiation GO:0045444 57 28 1,000 8,102E-03 0,05292447 ! base-excision repair GO:0006284 41 28 1,000 8,102E-03 0,05278334 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 8,102E-03 0,05264296 ! lipid oxidation GO:0034440 48 28 1,000 8,102E-03 0,05250332 GO:0019395|fatty acid oxidation, ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 8,675E-03 0,05606571 ! catechol metabolic process GO:0009712 55 29 1,000 8,675E-03 0,05591778 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 8,675E-03 0,05577063 ! somitogenesis GO:0001756 52 29 1,000 8,675E-03 0,05562425 ! phenol metabolic process GO:0018958 56 30 1,000 9,265E-03 0,05925381 ! immune response-activating signal transduction GO:0002757 58 30 1,000 9,265E-03 0,0590991 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 64 30 1,000 9,265E-03 0,05894519 ! regulation of cell cycle process GO:0010564 161 90 2,000 9,616E-03 0,06101569 ! cell junction assembly GO:0034329 85 31 1,000 9,873E-03 0,06248616 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 9,873E-03 0,0623247 ! fatty acid catabolic process GO:0009062 54 31 1,000 9,873E-03 0,06216407 ! response to heat GO:0009408 54 31 1,000 9,873E-03 0,06200426 ! gland development GO:0048732 220 91 2,000 9,909E-03 0,06206907 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01020689 0,06377349 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01049796 0,06542477 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01049796 0,06525829 ! hexose biosynthetic process GO:0019319 53 32 1,000 0,01049796 0,06509266 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01049796 0,06492787 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,01049796 0,06476391 ! regulation of pH GO:0006885 56 33 1,000 0,01114002 0,06855181 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01114002 0,06837957 ! regulation of calcium ion transport GO:0051924 60 33 1,000 0,01114002 0,06820819 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01114002 0,06803767 ! regulation of T cell activation GO:0050863 175 96 2,000 0,01145157 0,06976606 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01179898 0,07170373 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,01247465 0,07562177 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01247465 0,07543459 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01247465 0,07524833 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01277998 0,07690023 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 2,000 0,01277998 0,07671129 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01316687 0,07883986 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01316687 0,0786471 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,01316687 0,07845527 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01387546 0,08247625 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01387546 0,08227607 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01387546 0,08207685 ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,01387546 0,0818786 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01387546 0,0816813 ! cell junction organization GO:0034330 96 37 1,000 0,01387546 0,08148495 ! tissue remodeling GO:0048771 78 37 1,000 0,01387546 0,08128954 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01387546 0,08109507 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01387546 0,08090153 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01460024 0,08492473 ! meiosis I GO:0007127 74 38 1,000 0,01460024 0,084723 ! regulation of metal ion transport GO:0010959 71 39 1,000 0,01534105 0,08881085 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01534105 0,08860089 ! isoprenoid metabolic process GO:0006720 70 39 1,000 0,01534105 0,08839193 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01534105 0,08818395 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 0,01609771 0,09231621 ! lipid homeostasis GO:0055088 75 40 1,000 0,01609771 0,09210001 ! feeding behavior GO:0007631 69 41 1,000 0,01687006 0,09629334 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01687006 0,09606888 ! maintenance of protein location GO:0045185 95 41 1,000 0,01687006 0,09584547 ! ear morphogenesis GO:0042471 64 42 1,000 0,01765792 0,10008888 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01765792 0,09985719 ! T cell differentiation GO:0030217 93 42 1,000 0,01765792 0,09962658 ! cytokinesis GO:0000910 84 42 1,000 0,01765792 0,09939702 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,01765792 0,09916852 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01846114 0,10344167 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,01846114 0,10320496 ! segmentation GO:0035282 78 43 1,000 0,01846114 0,10296933 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,01927954 0,10728913 ! double-strand break repair GO:0006302 85 44 1,000 0,01927954 0,10704529 ! polyol metabolic process GO:0019751 77 45 1,000 0,02011297 0,11141948 ! developmental growth GO:0048589 88 45 1,000 0,02011297 0,11116739 ! pigmentation GO:0043473 103 46 1,000 0,02096126 0,11559447 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,02096126 0,11533412 ! mitochondrial transport GO:0006839 94 48 1,000 0,02270176 0,12463013 ! endosome transport GO:0016197 127 48 1,000 0,02270176 0,12435069 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02270176 0,1240725 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02270176 0,12379555 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,02270176 0,12351984 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02359366 0,12808738 ! JNK cascade GO:0007254 106 49 1,000 0,02359366 0,12780337 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02396366 0,12952042 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02396366 0,1292345 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02396366 0,12894984 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02396366 0,12866644 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02396366 0,12838427 ! neuron fate determination GO:0048664 7 5 0,000 0,02396366 0,12810335 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02396366 0,12782364 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02396366 0,12754516 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02396366 0,12726789 ! polyol transport GO:0015791 12 5 0,000 0,02396366 0,12699182 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02396366 0,12671695 ! response to superoxide GO:0000303 10 5 0,000 0,02396366 0,12644326 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02396366 0,12617075 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02396366 0,12589942 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02396366 0,12562925 ! female meiosis GO:0007143 10 5 0,000 0,02396366 0,12536023 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02396366 0,12509237 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02396366 0,12482565 ! hypothalamus development GO:0021854 9 5 0,000 0,02396366 0,12456006 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02396366 0,1242956 ! cobalt ion transport GO:0006824 11 5 0,000 0,02396366 0,12403226 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02396366 0,12377004 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02396366 0,12350892 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02396366 0,1232489 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02396366 0,12298998 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02396366 0,12273214 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02396366 0,12247537 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02396366 0,12221968 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02396366 0,12196506 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02396366 0,12171149 ! transposition GO:0032196 9 5 0,000 0,02396366 0,12145898 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02396366 0,12120751 ! negative chemotaxis GO:0050919 16 5 0,000 0,02396366 0,12095708 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02396366 0,12070769 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02396366 0,12045932 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02396366 0,12021197 ! behavioral response to pain GO:0048266 10 5 0,000 0,02396366 0,11996563 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02396366 0,1197203 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02396366 0,11947598 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02396366 0,11923265 ! micturition GO:0060073 9 5 0,000 0,02396366 0,1189903 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02396366 0,11874894 ! copulation GO:0007620 9 5 0,000 0,02396366 0,11850856 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02396366 0,11826915 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02396366 0,1180307 ! bioluminescence GO:0008218 9 5 0,000 0,02396366 0,11779322 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02396366 0,11755668 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02396366 0,1173211 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02396366 0,11708646 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02396366 0,11685275 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02396366 0,11661998 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02396366 0,11638813 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02396366 0,1161572 ! grooming behavior GO:0007625 6 5 0,000 0,02396366 0,11592719 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02396366 0,11569808 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02396366 0,11546988 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02396366 0,11524258 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02396366 0,11501617 ! response to protozoan GO:0001562 13 5 0,000 0,02396366 0,11479064 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02396366 0,11456601 ! endochondral ossification GO:0001958 17 5 0,000 0,02396366 0,11434224 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02396366 0,11411935 ! single strand break repair GO:0000012 8 5 0,000 0,02396366 0,11389733 ! parathyroid gland development GO:0060017 14 5 0,000 0,02396366 0,11367617 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02396366 0,11345587 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02396366 0,11323642 ! cytokine secretion GO:0050663 15 5 0,000 0,02396366 0,11301782 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02396366 0,11280006 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02396366 0,11258313 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02396366 0,11236704 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02396366 0,11215178 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02396366 0,11193734 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02396366 0,11172372 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02396366 0,11151091 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02396366 0,11129891 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02396366 0,11108772 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02396366 0,11087733 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02396366 0,11066773 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02396366 0,11045892 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02396366 0,1102509 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02396366 0,11004366 ! valine metabolic process GO:0006573 12 5 0,000 0,02396366 0,1098372 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02396366 0,10963151 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02396366 0,1094266 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02396366 0,10922244 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02396366 0,10901905 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02396366 0,10881641 ! polyol catabolic process GO:0046174 9 5 0,000 0,02396366 0,10861452 GO:0019405|alditol catabolic process, ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02396366 0,10841339 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02396366 0,10821299 ! muscle cell migration GO:0014812 8 5 0,000 0,02396366 0,10801334 ! mitochondrial fission GO:0000266 8 5 0,000 0,02396366 0,10781442 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02396366 0,10761623 ! mRNA transcription GO:0009299 10 5 0,000 0,02396366 0,10741877 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02396366 0,10722203 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02396366 0,10702601 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02396366 0,10683071 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02396366 0,10663612 ! monocyte activation GO:0042117 10 5 0,000 0,02396366 0,10644223 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02396366 0,10624905 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02396366 0,10605657 ! response to food GO:0032094 6 5 0,000 0,02396366 0,10586479 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02396366 0,1056737 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02396366 0,1054833 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02396366 0,10529358 ! forebrain neuron development GO:0021884 13 5 0,000 0,02396366 0,10510454 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02396366 0,10491618 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02396366 0,1047285 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02396366 0,10454148 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02396366 0,10435513 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02396366 0,10416945 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02396366 0,10398442 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02396366 0,10380005 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02396366 0,10361633 ! lipid glycosylation GO:0030259 7 5 0,000 0,02396366 0,10343327 ! nucleobase transport GO:0015851 6 5 0,000 0,02396366 0,10325084 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02396366 0,10306906 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02396366 0,10288792 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02396366 0,10270742 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02396366 0,10252755 ! basic amino acid transport GO:0015802 12 5 0,000 0,02396366 0,1023483 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02396366 0,10216968 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02396366 0,10199169 ! actin nucleation GO:0045010 11 5 0,000 0,02396366 0,10181431 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02396366 0,10163755 ! depurination GO:0045007 5 5 0,000 0,02396366 0,1014614 ! depyrimidination GO:0045008 10 5 0,000 0,02396366 0,10128586 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02396366 0,10111093 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02396366 0,1009366 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02396366 0,10076287 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02396366 0,10058974 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02396366 0,1004172 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02396366 0,10024525 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02396366 0,1000739 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02396366 0,09990312 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02396366 0,09973293 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02396366 0,09956331 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02396366 0,09939428 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02396366 0,09922581 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02396366 0,09905792 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02396366 0,09889059 ! response to arsenic GO:0046685 11 5 0,000 0,02396366 0,09872383 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02396366 0,09855762 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02396366 0,09839198 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02396366 0,09822689 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02396366 0,09806236 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02396366 0,09789838 ! response to mercury ion GO:0046689 8 5 0,000 0,02396366 0,09773494 ! response to cadmium ion GO:0046686 7 5 0,000 0,02396366 0,09757205 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02396366 0,0974097 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02396366 0,09724789 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02396366 0,09708661 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02396366 0,09692588 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02396366 0,09676567 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02396366 0,09660599 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02396366 0,09644683 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02396366 0,09628821 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02396366 0,0961301 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02396366 0,09597251 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02396366 0,09581543 ! embryonic cleavage GO:0040016 6 5 0,000 0,02396366 0,09565887 ! peroxisome fission GO:0016559 5 5 0,000 0,02396366 0,09550282 ! histone demethylation GO:0016577 13 5 0,000 0,02396366 0,09534728 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02396366 0,09519224 ! mitotic recombination GO:0006312 9 5 0,000 0,02396366 0,09503771 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02396366 0,09488368 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02396366 0,09473014 ! metaphase plate congression GO:0051310 7 5 0,000 0,02396366 0,09457711 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02396366 0,09442456 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02396366 0,09427251 ! enteric nervous system development GO:0048484 8 5 0,000 0,02396366 0,09412095 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02396366 0,09396987 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02396366 0,09381928 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02396366 0,09366917 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02396366 0,09351953 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02396366 0,09337038 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02396366 0,0932217 ! B cell homeostasis GO:0001782 13 5 0,000 0,02396366 0,0930735 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02396366 0,09292576 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02396366 0,09277849 ! metaphase GO:0051323 11 5 0,000 0,02396366 0,09263169 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02396366 0,09248535 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02396366 0,09233948 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02396366 0,09219406 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02396366 0,0920491 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02396366 0,0919046 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02396366 0,09176055 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02396366 0,09161695 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02396366 0,0914738 ! response to redox state GO:0051775 6 5 0,000 0,02396366 0,09133109 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02396366 0,09118883 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02396366 0,09104701 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02396366 0,09090563 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02396366 0,0907647 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02396366 0,09062419 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02396366 0,09048412 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02396366 0,09034449 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02396366 0,09020528 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02396366 0,09006651 ! striatum development GO:0021756 14 5 0,000 0,02396366 0,08992815 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02396366 0,08979023 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02396366 0,08965272 ! glial cell migration GO:0008347 10 5 0,000 0,02396366 0,08951564 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02396366 0,08937898 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02396366 0,08924273 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02396366 0,08910689 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02396366 0,08897147 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02396366 0,08883646 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02396366 0,08870186 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02396366 0,08856767 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02396366 0,08843388 ! neuroprotection GO:0043526 8 5 0,000 0,02396366 0,0883005 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02396366 0,08816751 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02396366 0,08803493 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02396366 0,08790275 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02396366 0,08777096 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02396366 0,08763956 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02396366 0,08750856 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02396366 0,08737795 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02396366 0,08724773 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02396366 0,0871179 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02396366 0,08698845 GO:0022011|myelination in the peripheral nervous system, ! protein palmitoylation GO:0018345 12 5 0,000 0,02396366 0,08685939 ! drug metabolic process GO:0017144 7 5 0,000 0,02396366 0,08673071 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02396366 0,08660241 ! organ regeneration GO:0031100 7 5 0,000 0,02396366 0,08647449 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02396366 0,08634695 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02396366 0,08621978 ! regulation of ion transport GO:0043269 86 50 1,000 0,02449978 0,08801908 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,02449978 0,08788983 ! endocrine system development GO:0035270 109 50 1,000 0,02449978 0,08776096 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,02541997 0,09092384 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,02541997 0,09079091 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02541997 0,09065837 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02541997 0,09052621 ! positive regulation of binding GO:0051099 88 52 1,000 0,02635406 0,09371612 ! Notch signaling pathway GO:0007219 111 52 1,000 0,02635406 0,0935799 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,02635406 0,09344408 ! histone modification GO:0016570 104 52 1,000 0,02635406 0,09330866 ! positive regulation of growth GO:0045927 96 53 1,000 0,02730191 0,09652469 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,02730191 0,0963852 ! synapse organization GO:0050808 102 53 1,000 0,02730191 0,09624612 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,02826335 0,0994919 ! regulation of translational initiation GO:0006446 87 54 1,000 0,02826335 0,09934874 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,02826335 0,099206 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,02826335 0,09906367 ! covalent chromatin modification GO:0016569 115 54 1,000 0,02826335 0,09892174 ! regulation of cell shape GO:0008360 142 54 1,000 0,02826335 0,09878022 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02868744 0,10011916 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02868744 0,09997634 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02868744 0,09983392 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02868744 0,09969191 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02868744 0,0995503 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02868744 0,09940909 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02868744 0,09926829 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02868744 0,09912788 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02868744 0,09898787 ! response to oxygen radical GO:0000305 11 6 0,000 0,02868744 0,09884825 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02868744 0,09870903 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02868744 0,0985702 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02868744 0,09843176 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02868744 0,09829371 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02868744 0,09815604 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02868744 0,09801876 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02868744 0,09788186 ! forebrain regionalization GO:0021871 9 6 0,000 0,02868744 0,09774534 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02868744 0,09760921 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02868744 0,09747345 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02868744 0,09733807 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02868744 0,09720307 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02868744 0,09706844 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02868744 0,09693418 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02868744 0,09680029 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02868744 0,09666677 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02868744 0,09653363 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02868744 0,09640084 ! malate metabolic process GO:0006108 13 6 0,000 0,02868744 0,09626842 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02868744 0,09613637 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02868744 0,09600467 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02868744 0,09587334 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02868744 0,09574237 ! protein refolding GO:0042026 15 6 0,000 0,02868744 0,09561175 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02868744 0,09548149 ! opsonization GO:0008228 8 6 0,000 0,02868744 0,09535158 ! mating behavior GO:0007617 7 6 0,000 0,02868744 0,09522203 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02868744 0,09509282 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02868744 0,09496397 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02868744 0,09483547 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02868744 0,09470731 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02868744 0,0945795 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02868744 0,09445204 ! toxin metabolic process GO:0009404 11 6 0,000 0,02868744 0,09432491 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02868744 0,09419813 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02868744 0,09407169 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02868744 0,09394559 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02868744 0,09381983 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02868744 0,0936944 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02868744 0,09356931 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02868744 0,09344455 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02868744 0,09332012 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02868744 0,09319603 ! thymic T cell selection GO:0045061 16 6 0,000 0,02868744 0,09307226 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02868744 0,09294882 ! protein lipoylation GO:0009249 10 6 0,000 0,02868744 0,09282571 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02868744 0,09270293 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02868744 0,09258046 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02868744 0,09245833 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02868744 0,09233651 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02868744 0,09221502 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02868744 0,09209384 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02868744 0,09197298 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02868744 0,09185244 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02868744 0,09173221 ! hyperosmotic response GO:0006972 10 6 0,000 0,02868744 0,0916123 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02868744 0,0914927 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02868744 0,09137342 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02868744 0,09125444 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02868744 0,09113578 ! urea metabolic process GO:0019627 7 6 0,000 0,02868744 0,09101742 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02868744 0,09089937 ! neutrophil activation GO:0042119 7 6 0,000 0,02868744 0,09078162 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02868744 0,09066418 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02868744 0,09054704 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02868744 0,09043021 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02868744 0,09031368 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02868744 0,09019744 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02868744 0,09008151 ! neuron apoptosis GO:0051402 15 6 0,000 0,02868744 0,08996587 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02868744 0,08985053 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02868744 0,08973548 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02868744 0,08962073 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02868744 0,08950627 ! carnitine transport GO:0015879 10 6 0,000 0,02868744 0,08939211 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02868744 0,08927823 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02868744 0,08916465 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02868744 0,08905135 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02868744 0,08893834 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02868744 0,08882562 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02868744 0,08871318 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02868744 0,08860103 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02868744 0,08848916 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02868744 0,08837757 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02868744 0,08826626 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02868744 0,08815524 ! response to UV-C GO:0010225 14 6 0,000 0,02868744 0,08804449 ! astrocyte development GO:0014002 16 6 0,000 0,02868744 0,08793402 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02868744 0,08782382 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02868744 0,08771391 ! interaction with symbiont GO:0051702 14 6 0,000 0,02868744 0,08760426 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02868744 0,0874949 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02868744 0,0873858 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02868744 0,08727698 ! response to copper ion GO:0046688 10 6 0,000 0,02868744 0,08716842 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02868744 0,08706014 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02868744 0,08695212 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02868744 0,08684438 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02868744 0,0867369 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02868744 0,08662968 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02868744 0,08652273 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02868744 0,08641604 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02868744 0,08630962 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02868744 0,08620346 ! Schwann cell development GO:0014044 15 6 0,000 0,02868744 0,08609756 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02868744 0,08599192 ! response to pheromone GO:0019236 6 6 0,000 0,02868744 0,08588653 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02868744 0,08578141 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02868744 0,08567654 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02868744 0,08557193 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02868744 0,08546758 ! subpallium development GO:0021544 15 6 0,000 0,02868744 0,08536347 ! neural tube patterning GO:0021532 8 6 0,000 0,02868744 0,08525963 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02868744 0,08515603 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02868744 0,08505268 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02868744 0,08494959 ! G2 phase GO:0051319 16 6 0,000 0,02868744 0,08484675 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02868744 0,08474415 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02868744 0,0846418 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02868744 0,0845397 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02868744 0,08443785 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02868744 0,08433624 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02868744 0,08423487 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02868744 0,08413375 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02868744 0,08403287 ! receptor internalization GO:0031623 11 6 0,000 0,02868744 0,08393223 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02868744 0,08383183 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02868744 0,08373167 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02868744 0,08363176 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02868744 0,08353208 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02868744 0,08343263 ! protein deubiquitination GO:0016579 16 6 0,000 0,02868744 0,08333343 ! protein destabilization GO:0031648 9 6 0,000 0,02868744 0,08323446 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02868744 0,08313572 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02868744 0,08303722 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02868744 0,08293895 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02868744 0,08284091 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02868744 0,08274311 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02868744 0,08264553 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02868744 0,08254819 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02868744 0,08245107 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02868744 0,08235419 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02868744 0,08225753 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02868744 0,08216109 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02868744 0,08206489 ! neural plate development GO:0001840 9 6 0,000 0,02868744 0,0819689 ! catecholamine transport GO:0051937 9 6 0,000 0,02868744 0,08187314 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02868744 0,08177761 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02868744 0,0816823 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02868744 0,08158721 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02868744 0,08149234 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02868744 0,08139769 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02868744 0,08130326 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02868744 0,08120905 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02868744 0,08111506 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02868744 0,08102129 GO:0055081|anion homeostasis, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,02923825 0,08248158 ! cell maturation GO:0048469 107 55 1,000 0,02923825 0,08238644 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03022644 0,08507281 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,03122778 0,08778995 ! muscle fiber development GO:0048747 131 57 1,000 0,03122778 0,08768905 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03122778 0,08758837 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,03122778 0,08748793 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,03224212 0,09022623 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,03224212 0,090123 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,03224212 0,09002 ! establishment of organelle localization GO:0051656 122 59 1,000 0,03326931 0,09278187 ! tRNA transcription GO:0009304 17 7 0,000 0,03338848 0,09300806 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03338848 0,09290213 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03338848 0,09279644 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03338848 0,09269098 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03338848 0,09258577 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03338848 0,0924808 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03338848 0,09237607 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03338848 0,09227157 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03338848 0,09216731 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03338848 0,09206328 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03338848 0,09195949 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03338848 0,09185593 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03338848 0,09175261 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03338848 0,09164951 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03338848 0,09154665 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03338848 0,09144402 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03338848 0,09134162 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03338848 0,09123945 ! glycolipid transport GO:0046836 11 7 0,000 0,03338848 0,0911375 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03338848 0,09103579 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03338848 0,0909343 ! neuron adhesion GO:0007158 14 7 0,000 0,03338848 0,09083304 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03338848 0,090732 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03338848 0,09063118 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03338848 0,0905306 ! pericardium development GO:0060039 16 7 0,000 0,03338848 0,09043023 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03338848 0,09033008 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03338848 0,09023016 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03338848 0,09013046 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03338848 0,09003098 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03338848 0,08993172 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03338848 0,08983267 ! rhythmic behavior GO:0007622 17 7 0,000 0,03338848 0,08973385 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03338848 0,08963524 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03338848 0,08953685 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03338848 0,08943867 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03338848 0,08934071 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03338848 0,08924296 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03338848 0,08914543 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03338848 0,08904811 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03338848 0,088951 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03338848 0,0888541 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03338848 0,08875742 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03338848 0,08866094 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03338848 0,08856468 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03338848 0,08846862 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03338848 0,08837277 ! spinal cord patterning GO:0021511 14 7 0,000 0,03338848 0,08827713 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03338848 0,08818169 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03338848 0,08808646 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03338848 0,08799144 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03338848 0,08789662 ! adrenal gland development GO:0030325 17 7 0,000 0,03338848 0,08780201 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03338848 0,0877076 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03338848 0,08761339 ! ovulation GO:0030728 10 7 0,000 0,03338848 0,08751938 ! adenohypophysis development GO:0021984 11 7 0,000 0,03338848 0,08742558 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03338848 0,08733198 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03338848 0,08723857 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03338848 0,08714537 ! microtubule nucleation GO:0007020 21 7 0,000 0,03338848 0,08705237 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03338848 0,08695956 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03338848 0,08686695 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03338848 0,08677454 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03338848 0,08668232 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03338848 0,0865903 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03338848 0,08649848 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03338848 0,08640685 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03338848 0,08631541 ! galactose metabolic process GO:0006012 13 7 0,000 0,03338848 0,08622417 ! vesicle fusion GO:0006906 20 7 0,000 0,03338848 0,08613312 ! response to dietary excess GO:0002021 8 7 0,000 0,03338848 0,08604226 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03338848 0,0859516 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03338848 0,08586112 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03338848 0,08577084 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03338848 0,08568074 ! organ growth GO:0035265 15 7 0,000 0,03338848 0,08559084 ! nucleoside transport GO:0015858 11 7 0,000 0,03338848 0,08550112 ! nucleoside salvage GO:0043174 11 7 0,000 0,03338848 0,08541159 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03338848 0,08532225 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03338848 0,08523309 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03338848 0,08514412 ! parturition GO:0007567 16 7 0,000 0,03338848 0,08505534 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03338848 0,08496674 ! rRNA modification GO:0000154 14 7 0,000 0,03338848 0,08487832 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03338848 0,08479009 ! spindle checkpoint GO:0031577 16 7 0,000 0,03338848 0,08470204 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03338848 0,08461418 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03338848 0,08452649 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03338848 0,08443899 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03338848 0,08435167 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03338848 0,08426453 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03338848 0,08417757 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03338848 0,08409079 ! fibrinolysis GO:0042730 11 7 0,000 0,03338848 0,08400419 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03338848 0,08391776 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03338848 0,08383152 ! eating behavior GO:0042755 8 7 0,000 0,03338848 0,08374545 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03338848 0,08365956 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03338848 0,08357384 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03338848 0,0834883 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03338848 0,08340293 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03338848 0,08331774 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03338848 0,08323272 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03338848 0,08314788 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03338848 0,0830632 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03338848 0,0829787 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03338848 0,08289438 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03338848 0,08281022 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03338848 0,08272623 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03338848 0,08264242 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03338848 0,08255877 ! histone ubiquitination GO:0016574 9 7 0,000 0,03338848 0,08247529 ! regulation of meiosis GO:0040020 12 7 0,000 0,03338848 0,08239199 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03338848 0,08230885 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03338848 0,08222587 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03338848 0,08214307 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03338848 0,08206043 ! transcription termination GO:0006353 14 7 0,000 0,03338848 0,08197796 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03338848 0,08189565 ! anaphase GO:0051322 18 7 0,000 0,03338848 0,08181351 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03338848 0,08173153 ! axonal fasciculation GO:0007413 19 7 0,000 0,03338848 0,08164972 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03338848 0,08156807 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03338848 0,08148658 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03338848 0,08140526 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03338848 0,08132409 ! diuresis GO:0030146 12 7 0,000 0,03338848 0,08124309 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03338848 0,08116226 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03338848 0,08108158 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03338848 0,08100106 ! antibiotic transport GO:0042891 9 7 0,000 0,03338848 0,0809207 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03338848 0,0808405 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03338848 0,08076046 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03338848 0,08068058 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03338848 0,08060086 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03338848 0,08052129 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03338848 0,08044188 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03338848 0,08036263 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03338848 0,08028353 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03338848 0,08020459 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03338848 0,0801258 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03338848 0,08004717 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03338848 0,07996869 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03338848 0,07989037 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03338848 0,0798122 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03338848 0,07973418 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03338848 0,07965631 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03338848 0,0795786 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03338848 0,07950104 ! muscle adaptation GO:0043500 13 7 0,000 0,03338848 0,07942363 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03338848 0,07934637 ! retina homeostasis GO:0001895 12 7 0,000 0,03338848 0,07926926 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03338848 0,0791923 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03338848 0,07911549 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03338848 0,07903882 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03338848 0,07896231 ! lipid modification GO:0030258 112 60 1,000 0,0343092 0,0810613 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,03536165 0,08346717 ! regulation of heart contraction GO:0008016 123 61 1,000 0,03536165 0,0833866 ! viral reproductive process GO:0022415 132 62 1,000 0,03642652 0,08581484 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,03642652 0,08573217 ! regulation of mitosis GO:0007088 112 63 1,000 0,03750366 0,08818233 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,03750366 0,08809754 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03806691 0,08933473 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03806691 0,089249 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03806691 0,08916343 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03806691 0,08907802 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03806691 0,08899278 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03806691 0,0889077 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03806691 0,08882279 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03806691 0,08873803 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03806691 0,08865344 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03806691 0,08856901 ! meiotic prophase I GO:0007128 14 8 0,000 0,03806691 0,08848474 ! response to zinc ion GO:0010043 12 8 0,000 0,03806691 0,08840063 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03806691 0,08831667 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03806691 0,08823288 ! oligopeptide transport GO:0006857 16 8 0,000 0,03806691 0,08814925 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03806691 0,08806577 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03806691 0,08798246 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03806691 0,0878993 ! signal peptide processing GO:0006465 12 8 0,000 0,03806691 0,0878163 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03806691 0,08773345 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03806691 0,08765076 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03806691 0,08756823 ! succinate metabolic process GO:0006105 17 8 0,000 0,03806691 0,08748585 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03806691 0,08740363 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03806691 0,08732156 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03806691 0,08723964 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03806691 0,08715788 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03806691 0,08707627 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03806691 0,08699482 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03806691 0,08691351 ! reflex GO:0060004 17 8 0,000 0,03806691 0,08683236 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03806691 0,08675136 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03806691 0,08667051 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03806691 0,08658981 ! pigment granule organization GO:0048753 17 8 0,000 0,03806691 0,08650926 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03806691 0,08642886 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03806691 0,08634861 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03806691 0,08626851 ! histidine catabolic process GO:0006548 10 8 0,000 0,03806691 0,08618856 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03806691 0,08610876 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03806691 0,0860291 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03806691 0,08594959 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03806691 0,08587023 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03806691 0,08579101 ! melanin metabolic process GO:0006582 17 8 0,000 0,03806691 0,08571194 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03806691 0,08563302 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03806691 0,08555424 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03806691 0,0854756 ! macrophage activation GO:0042116 13 8 0,000 0,03806691 0,08539711 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03806691 0,08531877 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03806691 0,08524057 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03806691 0,08516251 ! purine salvage GO:0043101 12 8 0,000 0,03806691 0,08508459 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03806691 0,08500682 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03806691 0,08492919 ! osteoblast development GO:0002076 17 8 0,000 0,03806691 0,0848517 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03806691 0,08477435 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03806691 0,08469714 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03806691 0,08462007 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03806691 0,08454314 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03806691 0,08446636 ! response to UV-B GO:0010224 17 8 0,000 0,03806691 0,08438971 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03806691 0,0843132 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03806691 0,08423683 ! intermediate filament organization GO:0045109 12 8 0,000 0,03806691 0,0841606 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03806691 0,0840845 ! cellular extravasation GO:0045123 13 8 0,000 0,03806691 0,08400854 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03806691 0,08393272 ! response to antibiotic GO:0046677 11 8 0,000 0,03806691 0,08385704 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03806691 0,08378149 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03806691 0,08370608 ! DNA topological change GO:0006265 12 8 0,000 0,03806691 0,08363081 ! response to tropane GO:0014073 15 8 0,000 0,03806691 0,08355567 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03806691 0,08348066 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03806691 0,08340579 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03806691 0,08333106 ! mast cell activation GO:0045576 14 8 0,000 0,03806691 0,08325645 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03806691 0,08318198 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03806691 0,08310765 ! gas homeostasis GO:0033483 14 8 0,000 0,03806691 0,08303344 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03806691 0,08295937 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03806691 0,08288543 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03806691 0,08281163 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03806691 0,08273795 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03806691 0,08266441 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03806691 0,08259099 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03806691 0,08251771 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03806691 0,08244456 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03806691 0,08237153 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03806691 0,08229864 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03806691 0,08222587 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03806691 0,08215323 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03806691 0,08208072 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03806691 0,08200834 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03806691 0,08193609 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03806691 0,08186396 ! hormone catabolic process GO:0042447 17 8 0,000 0,03806691 0,08179196 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03806691 0,08172009 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03806691 0,08164834 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03806691 0,08157672 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03806691 0,08150522 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03806691 0,08143385 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03806691 0,08136261 ! adult feeding behavior GO:0008343 10 8 0,000 0,03806691 0,08129148 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03806691 0,08122049 ! ATP catabolic process GO:0006200 11 8 0,000 0,03806691 0,08114961 ! blastocyst growth GO:0001832 19 8 0,000 0,03806691 0,08107886 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03806691 0,08100824 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03806691 0,08093774 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03806691 0,08086735 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03806691 0,0807971 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03806691 0,08072696 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03806691 0,08065695 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03806691 0,08058705 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03806691 0,08051728 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03806691 0,08044763 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03806691 0,0803781 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03806691 0,08030869 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03806691 0,08023939 ! protein prenylation GO:0018342 21 8 0,000 0,03806691 0,08017022 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03806691 0,08010117 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03806691 0,08003224 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03806691 0,07996342 ! ear development GO:0043583 114 66 1,000 0,04080728 0,08564621 ! activation of MAPK activity GO:0000187 124 67 1,000 0,04193209 0,08793142 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,04193209 0,08785601 ! axon extension GO:0048675 16 9 0,000 0,04272282 0,08943603 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04272282 0,08935946 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04272282 0,08928302 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04272282 0,08920671 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04272282 0,08913053 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04272282 0,08905448 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04272282 0,08897856 ! reproductive behavior GO:0019098 22 9 0,000 0,04272282 0,08890277 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04272282 0,08882711 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04272282 0,08875157 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04272282 0,08867617 ! UTP metabolic process GO:0046051 10 9 0,000 0,04272282 0,08860089 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04272282 0,08852574 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04272282 0,08845072 ! artery development GO:0060840 25 9 0,000 0,04272282 0,08837583 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04272282 0,08830106 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04272282 0,08822642 ! equilibrioception GO:0050957 20 9 0,000 0,04272282 0,0881519 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04272282 0,08807751 ! chemosensory behavior GO:0007635 21 9 0,000 0,04272282 0,08800325 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04272282 0,08792911 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04272282 0,08785509 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04272282 0,0877812 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04272282 0,08770744 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04272282 0,0876338 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04272282 0,08756028 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04272282 0,08748688 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04272282 0,08741361 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04272282 0,08734046 ! protein targeting to ER GO:0045047 25 9 0,000 0,04272282 0,08726743 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04272282 0,08719453 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04272282 0,08712175 ! T cell selection GO:0045058 27 9 0,000 0,04272282 0,08704908 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,04272282 0,08697654 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04272282 0,08690412 ! glycine catabolic process GO:0006546 15 9 0,000 0,04272282 0,08683182 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04272282 0,08675964 ! endosome organization GO:0007032 20 9 0,000 0,04272282 0,08668758 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04272282 0,08661564 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04272282 0,08654382 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04272282 0,08647212 ! mannose metabolic process GO:0006013 13 9 0,000 0,04272282 0,08640054 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04272282 0,08632907 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04272282 0,08625773 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04272282 0,0861865 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04272282 0,08611539 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04272282 0,0860444 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04272282 0,08597352 ! retinol metabolic process GO:0042572 20 9 0,000 0,04272282 0,08590276 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04272282 0,08583211 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04272282 0,08576159 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04272282 0,08569118 ! macrophage differentiation GO:0030225 15 9 0,000 0,04272282 0,08562088 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04272282 0,0855507 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04272282 0,08548063 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04272282 0,08541068 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04272282 0,08534084 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04272282 0,08527112 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04272282 0,08520151 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04272282 0,08513202 ! erythrocyte development GO:0048821 17 9 0,000 0,04272282 0,08506263 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04272282 0,08499336 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04272282 0,08492421 ! renal water homeostasis GO:0003091 15 9 0,000 0,04272282 0,08485516 ! postreplication repair GO:0006301 25 9 0,000 0,04272282 0,08478623 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04272282 0,08471741 ! icosanoid secretion GO:0032309 15 9 0,000 0,04272282 0,0846487 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04272282 0,08458011 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04272282 0,08451162 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04272282 0,08444325 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04272282 0,08437498 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04272282 0,08430683 ! sterol catabolic process GO:0016127 14 9 0,000 0,04272282 0,08423878 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04272282 0,08417085 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04272282 0,08410302 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04272282 0,08403531 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04272282 0,0839677 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04272282 0,0839002 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04272282 0,08383281 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04272282 0,08376553 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04272282 0,08369836 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04272282 0,08363129 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04272282 0,08356433 ! purine base metabolic process GO:0006144 25 9 0,000 0,04272282 0,08349748 ! pigment granule transport GO:0051904 17 9 0,000 0,04272282 0,08343074 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04272282 0,0833641 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04272282 0,08329757 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04272282 0,08323114 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04272282 0,08316482 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04272282 0,08309861 ! mitochondrion localization GO:0051646 18 9 0,000 0,04272282 0,0830325 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,04306848 0,08363775 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,04306848 0,08357132 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,04306848 0,08350499 ! viral reproduction GO:0016032 142 68 1,000 0,04306848 0,08343877 ! regulation of lipase activity GO:0060191 137 68 1,000 0,04306848 0,08337265 ! adaptive immune response GO:0002250 126 68 1,000 0,04306848 0,08330664 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,04306848 0,08324073 ! urogenital system development GO:0001655 149 69 1,000 0,04421629 0,08539162 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,04421629 0,08532417 ! activation of immune response GO:0002253 120 70 1,000 0,04537541 0,08749181 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,04537541 0,08742281 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,04654569 0,08960687 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04735633 0,09109568 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04735633 0,091024 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04735633 0,09095244 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04735633 0,090881 ! associative learning GO:0008306 21 10 0,000 0,04735633 0,09080966 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04735633 0,09073844 ! phosphate transport GO:0006817 24 10 0,000 0,04735633 0,09066733 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04735633 0,09059633 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04735633 0,09052544 ! CTP metabolic process GO:0046036 11 10 0,000 0,04735633 0,09045466 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04735633 0,09038399 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04735633 0,09031343 ! GTP metabolic process GO:0046039 11 10 0,000 0,04735633 0,09024299 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04735633 0,09017265 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04735633 0,09010242 ! social behavior GO:0035176 29 10 0,000 0,04735633 0,0900323 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04735633 0,08996229 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04735633 0,08989239 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04735633 0,0898226 ! androgen metabolic process GO:0008209 17 10 0,000 0,04735633 0,08975292 ! phospholipid efflux GO:0033700 19 10 0,000 0,04735633 0,08968334 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04735633 0,08961387 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04735633 0,08954451 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04735633 0,08947526 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04735633 0,08940611 ! pathogenesis GO:0009405 17 10 0,000 0,04735633 0,08933707 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04735633 0,08926814 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04735633 0,08919931 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04735633 0,08913059 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04735633 0,08906198 ! endoderm development GO:0007492 18 10 0,000 0,04735633 0,08899347 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04735633 0,08892506 ! arginine catabolic process GO:0006527 17 10 0,000 0,04735633 0,08885677 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04735633 0,08878857 ! proline metabolic process GO:0006560 13 10 0,000 0,04735633 0,08872048 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04735633 0,0886525 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04735633 0,08858462 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04735633 0,08851684 ! V(D)J recombination GO:0033151 34 10 0,000 0,04735633 0,08844917 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04735633 0,0883816 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04735633 0,08831413 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04735633 0,08824677 ! B cell proliferation GO:0042100 19 10 0,000 0,04735633 0,0881795 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04735633 0,08811235 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04735633 0,08804529 ! multicellular organism growth GO:0035264 19 10 0,000 0,04735633 0,08797833 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04735633 0,08791148 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04735633 0,08784473 ! ruffle organization GO:0031529 17 10 0,000 0,04735633 0,08777808 ! epithelial cell development GO:0002064 21 10 0,000 0,04735633 0,08771153 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04735633 0,08764508 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04735633 0,08757874 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04735633 0,08751249 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04735633 0,08744634 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04735633 0,08738029 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04735633 0,08731435 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,04735633 0,0872485 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04735633 0,08718275 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04735633 0,0871171 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04735633 0,08705155 ! segment specification GO:0007379 15 10 0,000 0,04735633 0,0869861 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04735633 0,08692074 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,04735633 0,08685549 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04735633 0,08679033 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04735633 0,08672527 ! response to dsRNA GO:0043331 23 10 0,000 0,04735633 0,08666031 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04735633 0,08659544 ! melanosome localization GO:0032400 16 10 0,000 0,04735633 0,08653067 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04735633 0,086466 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04735633 0,08640143 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04735633 0,08633695 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04735633 0,08627256 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04735633 0,08620828 ! induction of an organ GO:0001759 17 10 0,000 0,04735633 0,08614409 ! mRNA cleavage GO:0006379 18 10 0,000 0,04735633 0,08607999 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04735633 0,08601599 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04735633 0,08595209 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04735633 0,08588828 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04735633 0,08582456 ! salivary gland development GO:0007431 28 10 0,000 0,04735633 0,08576094 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04735633 0,08569741 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04735633 0,08563398 ! midbrain development GO:0030901 14 10 0,000 0,04735633 0,08557064 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04735633 0,0855074 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04735633 0,08544425 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04735633 0,08538119 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04735633 0,08531822 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04735633 0,08525535 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04735633 0,08519257 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04735633 0,08512988 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04735633 0,08506729 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04735633 0,08500478 ! detection of calcium ion GO:0005513 24 10 0,000 0,04735633 0,08494237 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04735633 0,08488005 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04735633 0,08481782 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04735633 0,08475568 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04735633 0,08469364 ! response to nicotine GO:0035094 20 10 0,000 0,04735633 0,08463168 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04735633 0,08456982 ! organelle localization GO:0051640 155 74 1,000 0,05012217 0,08944373 ! reproductive structure development GO:0048608 131 75 1,000 0,05133578 0,09154256 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,05133578 0,09147579 ! axon guidance GO:0007411 162 75 1,000 0,05133578 0,09140911 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05196754 0,09246664 ! respiratory burst GO:0045730 17 11 0,000 0,05196754 0,09239934 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05196754 0,09233214 ! neuron fate specification GO:0048665 18 11 0,000 0,05196754 0,09226504 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05196754 0,09219803 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05196754 0,09213113 ! thyroid gland development GO:0030878 26 11 0,000 0,05196754 0,09206432 ! synapsis GO:0007129 14 11 0,000 0,05196754 0,0919976 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05196754 0,09193099 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05196754 0,09186447 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,05196754 0,09179804 ! response to pain GO:0048265 27 11 0,000 0,05196754 0,09173171 ! bone resorption GO:0045453 16 11 0,000 0,05196754 0,09166548 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05196754 0,09159935 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05196754 0,0915333 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05196754 0,09146736 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05196754 0,09140151 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05196754 0,09133575 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05196754 0,09127009 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05196754 0,09120452 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05196754 0,09113905 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05196754 0,09107367 ! UV protection GO:0009650 20 11 0,000 0,05196754 0,09100838 ! adult heart development GO:0007512 16 11 0,000 0,05196754 0,09094319 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05196754 0,09087809 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05196754 0,09081309 ! macroautophagy GO:0016236 19 11 0,000 0,05196754 0,09074817 ! temperature homeostasis GO:0001659 18 11 0,000 0,05196754 0,09068335 ! behavioral fear response GO:0001662 27 11 0,000 0,05196754 0,09061862 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 0,000 0,05196754 0,09055399 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05196754 0,09048945 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05196754 0,090425 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05196754 0,09036064 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05196754 0,09029637 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05196754 0,09023219 ! regulation of organ growth GO:0046620 14 11 0,000 0,05196754 0,09016811 ! pigment granule localization GO:0051875 20 11 0,000 0,05196754 0,09010411 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05196754 0,09004021 ! vasoconstriction GO:0042310 20 11 0,000 0,05196754 0,0899764 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05196754 0,08991267 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05196754 0,08984904 ! embryonic axis specification GO:0000578 19 11 0,000 0,05196754 0,0897855 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05196754 0,08972204 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05196754 0,08965868 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05196754 0,08959541 ! DNA methylation GO:0006306 19 11 0,000 0,05196754 0,08953222 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05196754 0,08946913 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05196754 0,08940612 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05196754 0,0893432 ! prophase GO:0051324 17 11 0,000 0,05196754 0,08928038 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05196754 0,08921763 ! nucleosome positioning GO:0016584 15 11 0,000 0,05196754 0,08915498 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05196754 0,08909242 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05196754 0,08902994 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05196754 0,08896755 ! apical protein localization GO:0045176 18 11 0,000 0,05196754 0,08890525 ! acid secretion GO:0046717 20 11 0,000 0,05196754 0,08884303 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05196754 0,0887809 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05196754 0,08871886 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05196754 0,08865691 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05196754 0,08859504 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05196754 0,08853326 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05196754 0,08847156 ! cholesterol efflux GO:0033344 21 11 0,000 0,05196754 0,08840995 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05196754 0,08834843 ! oocyte development GO:0048599 20 11 0,000 0,05196754 0,08828699 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05196754 0,08822564 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,05196754 0,08816437 ! embryonic gut development GO:0048566 19 11 0,000 0,05196754 0,08810319 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05196754 0,08804209 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05196754 0,08798108 ! activation of innate immune response GO:0002218 16 11 0,000 0,05196754 0,08792015 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05196754 0,0878593 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05196754 0,08779854 ! lysogeny GO:0030069 22 11 0,000 0,05196754 0,08773787 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05196754 0,08767727 ! nucleus localization GO:0051647 22 11 0,000 0,05196754 0,08761677 ! regulation of blood pressure GO:0008217 134 76 1,000 0,05255989 0,08855435 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,05503911 0,0926675 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,05629396 0,09471498 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,05629396 0,09464979 ! steroid biosynthetic process GO:0006694 146 79 1,000 0,05629396 0,0945847 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05655656 0,09496059 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05655656 0,09489537 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05655656 0,09483024 ! mating GO:0007618 17 12 0,000 0,05655656 0,0947652 ! protein complex disassembly GO:0043241 28 12 0,000 0,05655656 0,09470025 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 29 12 0,000 0,05655656 0,09463539 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05655656 0,09457061 ! T cell proliferation GO:0042098 32 12 0,000 0,05655656 0,09450593 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05655656 0,09444133 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05655656 0,09437682 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05655656 0,0943124 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05655656 0,09424807 ! drug transport GO:0015893 16 12 0,000 0,05655656 0,09418382 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05655656 0,09411966 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05655656 0,09405559 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05655656 0,09399161 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05655656 0,09392771 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05655656 0,0938639 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05655656 0,09380018 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05655656 0,09373654 ! lipid digestion GO:0044241 21 12 0,000 0,05655656 0,09367299 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05655656 0,09360953 ! entry into host cell GO:0030260 34 12 0,000 0,05655656 0,09354615 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05655656 0,09348286 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05655656 0,09341965 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05655656 0,09335653 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05655656 0,09329349 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05655656 0,09323054 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05655656 0,09316768 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05655656 0,0931049 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05655656 0,0930422 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05655656 0,09297959 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05655656 0,09291706 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05655656 0,09285461 ! cranial nerve development GO:0021545 23 12 0,000 0,05655656 0,09279225 ! fucose catabolic process GO:0019317 25 12 0,000 0,05655656 0,09272998 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05655656 0,09266778 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05655656 0,09260567 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05655656 0,09254365 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05655656 0,0924817 ! zymogen activation GO:0031638 18 12 0,000 0,05655656 0,09241984 ! T cell homeostasis GO:0043029 28 12 0,000 0,05655656 0,09235806 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05655656 0,09229637 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05655656 0,09223476 ! oocyte differentiation GO:0009994 21 12 0,000 0,05655656 0,09217323 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05655656 0,09211178 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05655656 0,09205041 ! defense response to fungus GO:0050832 15 12 0,000 0,05655656 0,09198912 ! developmental induction GO:0031128 22 12 0,000 0,05655656 0,09192792 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,05655656 0,0918668 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05655656 0,09180576 ! response to cold GO:0009409 17 12 0,000 0,05655656 0,0917448 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05655656 0,09168392 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05655656 0,09162312 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,05755881 0,09318501 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,05883354 0,09518565 ! protein import into nucleus GO:0006606 174 82 1,000 0,060118 0,09719939 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06112349 0,09875971 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06112349 0,09869444 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06112349 0,09862925 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06112349 0,09856415 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06112349 0,09849913 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06112349 0,0984342 ! peroxisomal transport GO:0043574 28 13 0,000 0,06112349 0,09836936 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06112349 0,0983046 ! cartilage condensation GO:0001502 22 13 0,000 0,06112349 0,09823992 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06112349 0,09817533 ! organelle fusion GO:0048284 36 13 0,000 0,06112349 0,09811083 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06112349 0,09804641 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06112349 0,09798208 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06112349 0,09791782 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06112349 0,09785366 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06112349 0,09778958 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06112349 0,09772558 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06112349 0,09766166 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06112349 0,09759783 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06112349 0,09753408 ! methionine metabolic process GO:0006555 31 13 0,000 0,06112349 0,09747042 ! plasma membrane organization GO:0007009 27 13 0,000 0,06112349 0,09740684 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06112349 0,09734334 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06112349 0,09727992 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06112349 0,09721659 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06112349 0,09715334 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06112349 0,09709017 ! exocrine system development GO:0035272 34 13 0,000 0,06112349 0,09702708 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06112349 0,09696408 ! monoamine transport GO:0015844 21 13 0,000 0,06112349 0,09690116 ! L-glutamate transport GO:0015813 30 13 0,000 0,06112349 0,09683832 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06112349 0,09677556 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06112349 0,09671288 ! protein homotetramerization GO:0051289 24 13 0,000 0,06112349 0,09665028 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06112349 0,09658776 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06112349 0,09652533 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06112349 0,09646297 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06112349 0,0964007 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06112349 0,09633851 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06112349 0,09627639 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06112349 0,09621436 ! histone methylation GO:0016571 29 13 0,000 0,06112349 0,0961524 ! chromatin silencing GO:0006342 29 13 0,000 0,06112349 0,09609053 ! gland morphogenesis GO:0022612 31 13 0,000 0,06112349 0,09602873 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06112349 0,09596702 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06112349 0,09590538 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06112349 0,09584383 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06112349 0,09578235 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06112349 0,09572095 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06112349 0,09565963 ! spleen development GO:0048536 24 13 0,000 0,06112349 0,09559839 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06112349 0,09553723 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06112349 0,09547614 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06112349 0,09541513 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06112349 0,0953542 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06112349 0,09529335 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06112349 0,09523258 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06112349 0,09517188 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06112349 0,09511126 ! insulin secretion GO:0030073 24 13 0,000 0,06112349 0,09505072 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06112349 0,09499026 ! acrosome reaction GO:0007340 19 13 0,000 0,06112349 0,09492987 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06112349 0,09486956 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06112349 0,09480932 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,0614121 0,09519654 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,0614121 0,09513618 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,0614121 0,09507589 ! T cell activation GO:0042110 189 84 1,000 0,06271569 0,09703258 ! response to nutrient GO:0007584 135 84 1,000 0,06271569 0,09697116 ! regulation of ligase activity GO:0051340 147 84 1,000 0,06271569 0,09690983 ! negative regulation of transport GO:0051051 164 85 1,000 0,06402867 0,09887613 ! cholesterol metabolic process GO:0008203 148 85 1,000 0,06402867 0,09881367 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,06402867 0,09875129 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,06402867 0,09868898 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,06535091 0,10066347 ! regulation of lyase activity GO:0051339 169 86 1,000 0,06535091 0,10060004 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,06535091 0,10053669 GO:0002696|positive regulation of leukocyte activation, ! rRNA transcription GO:0009303 28 14 0,000 0,06566844 0,10096161 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06566844 0,10089812 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,06566844 0,1008347 ! water transport GO:0006833 21 14 0,000 0,06566844 0,10077136 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06566844 0,1007081 ! non-recombinational repair GO:0000726 29 14 0,000 0,06566844 0,10064492 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06566844 0,10058182 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06566844 0,1005188 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06566844 0,10045586 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06566844 0,10039299 ! lipid localization GO:0010876 32 14 0,000 0,06566844 0,10033021 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,06566844 0,1002675 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,06566844 0,10020488 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06566844 0,10014233 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06566844 0,10007985 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06566844 0,10001746 ! arginine metabolic process GO:0006525 21 14 0,000 0,06566844 0,09995514 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06566844 0,09989291 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06566844 0,09983074 ! regulation of heart rate GO:0002027 25 14 0,000 0,06566844 0,09976866 ! fear response GO:0042596 34 14 0,000 0,06566844 0,09970665 ! organic alcohol transport GO:0015850 29 14 0,000 0,06566844 0,09964472 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,06566844 0,09958287 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,06566844 0,0995211 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 28 14 0,000 0,06566844 0,0994594 ! bone mineralization GO:0030282 18 14 0,000 0,06566844 0,09939777 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06566844 0,09933623 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06566844 0,09927476 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06566844 0,09921336 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,06566844 0,09915204 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06566844 0,0990908 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06566844 0,09902963 ! ribosome assembly GO:0042255 18 14 0,000 0,06566844 0,09896854 ! cerebellum development GO:0021549 23 14 0,000 0,06566844 0,09890752 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06566844 0,09884658 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06566844 0,09878572 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06566844 0,09872493 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06566844 0,09866421 ! NADP metabolic process GO:0006739 24 14 0,000 0,06566844 0,09860357 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06566844 0,098543 ! oxygen transport GO:0015671 22 14 0,000 0,06566844 0,09848251 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06566844 0,09842209 ! male genitalia development GO:0030539 26 14 0,000 0,06566844 0,09836174 ! regulation of axon extension GO:0030516 43 14 0,000 0,06566844 0,09830147 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06566844 0,09824128 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,06566844 0,09818115 ! regulation of protein transport GO:0051223 165 87 1,000 0,06668229 0,09963598 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,069372 0,10359156 ! protein localization in nucleus GO:0034504 192 89 1,000 0,069372 0,10352828 ! regulation of neurological system process GO:0031644 175 89 1,000 0,069372 0,10346507 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07019152 0,10462348 ! lactation GO:0007595 30 15 0,000 0,07019152 0,10455969 ! reproductive cellular process GO:0048610 22 15 0,000 0,07019152 0,10449597 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07019152 0,10443233 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07019152 0,10436877 ! superoxide anion generation GO:0042554 22 15 0,000 0,07019152 0,10430529 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07019152 0,10424188 ! copper ion transport GO:0006825 22 15 0,000 0,07019152 0,10417855 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07019152 0,10411529 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07019152 0,10405212 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07019152 0,10398902 ! sulfate transport GO:0008272 27 15 0,000 0,07019152 0,10392599 ! response to cAMP GO:0051591 25 15 0,000 0,07019152 0,10386305 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07019152 0,10380018 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,07019152 0,10373738 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07019152 0,10367466 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07019152 0,10361202 ! vesicle coating GO:0006901 38 15 0,000 0,07019152 0,10354945 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,07019152 0,10348696 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07019152 0,10342454 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07019152 0,1033622 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07019152 0,10329993 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07019152 0,10323774 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07019152 0,10317563 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07019152 0,10311358 ! histone deacetylation GO:0016575 24 15 0,000 0,07019152 0,10305162 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07019152 0,10298972 ! water homeostasis GO:0030104 28 15 0,000 0,07019152 0,1029279 ! cofactor transport GO:0051181 30 15 0,000 0,07019152 0,10286616 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07019152 0,10280449 ! intestinal absorption GO:0050892 31 15 0,000 0,07019152 0,10274289 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07019152 0,10268137 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07019152 0,10261992 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,07019152 0,10255855 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07019152 0,10249724 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07019152 0,10243602 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07019152 0,10237486 ! actin filament polymerization GO:0030041 27 15 0,000 0,07019152 0,10231378 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07019152 0,10225277 ! response to unfolded protein GO:0006986 139 90 1,000 0,0707301 0,10297594 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,07209687 0,10490331 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,07209687 0,10484086 ! bone development GO:0060348 206 92 1,000 0,0734722 0,10677727 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,07469283 0,10848668 ! positive regulation of cell size GO:0045793 29 16 0,000 0,07469283 0,10842222 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07469283 0,10835783 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07469283 0,10829353 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07469283 0,10822929 ! bone remodeling GO:0046849 28 16 0,000 0,07469283 0,10816514 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,07469283 0,10810106 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,07469283 0,10803706 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07469283 0,10797313 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07469283 0,10790928 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07469283 0,1078455 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,07469283 0,1077818 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07469283 0,10771818 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07469283 0,10765463 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07469283 0,10759115 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07469283 0,10752775 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07469283 0,10746442 ! pituitary gland development GO:0021983 30 16 0,000 0,07469283 0,10740117 ! response to osmotic stress GO:0006970 27 16 0,000 0,07469283 0,10733799 ! lysosomal transport GO:0007041 31 16 0,000 0,07469283 0,10727489 ! fructose metabolic process GO:0006000 25 16 0,000 0,07469283 0,10721186 ! L-amino acid transport GO:0015807 33 16 0,000 0,07469283 0,10714891 ! stem cell development GO:0048864 46 16 0,000 0,07469283 0,10708603 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07469283 0,10702322 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07469283 0,10696049 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07469283 0,10689783 ! negative regulation of immune response GO:0050777 38 16 0,000 0,07469283 0,10683524 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07469283 0,10677273 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,07469283 0,10671029 ! neuron recognition GO:0008038 40 16 0,000 0,07469283 0,10664792 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07469283 0,10658563 ! tissue regeneration GO:0042246 27 16 0,000 0,07469283 0,1065234 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07469283 0,10646125 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07469283 0,10639918 ! biomineral formation GO:0031214 22 16 0,000 0,07469283 0,10633717 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07469283 0,10627524 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07469283 0,10621338 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07469283 0,10615159 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07469283 0,10608988 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07469283 0,10602823 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07469283 0,10596666 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07469283 0,10590516 ! peptide hormone processing GO:0016486 27 16 0,000 0,07469283 0,10584373 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,07485598 0,10601343 ! vitamin metabolic process GO:0006766 153 93 1,000 0,07485598 0,105952 ! female pregnancy GO:0007565 166 94 1,000 0,07624809 0,10785992 ! sterol metabolic process GO:0016125 166 94 1,000 0,07624809 0,10779751 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,07624809 0,10773516 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,07764843 0,10965035 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,07764843 0,109587 ! sex differentiation GO:0007548 171 96 1,000 0,07905687 0,11151035 ! response to protein stimulus GO:0051789 158 96 1,000 0,07905687 0,11144601 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,07917248 0,11154462 ! metencephalon development GO:0022037 32 17 0,000 0,07917248 0,11148033 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,07917248 0,11141611 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,07917248 0,11135197 ! filopodium assembly GO:0046847 42 17 0,000 0,07917248 0,1112879 ! gene silencing by RNA GO:0031047 38 17 0,000 0,07917248 0,1112239 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,07917248 0,11115998 ! glial cell development GO:0021782 28 17 0,000 0,07917248 0,11109613 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,07917248 0,11103236 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,07917248 0,11096865 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,07917248 0,11090503 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,07917248 0,11084147 ! myoblast differentiation GO:0045445 50 17 0,000 0,07917248 0,11077799 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,07917248 0,11071458 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,07917248 0,11065124 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,07917248 0,11058797 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,07917248 0,11052478 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,07917248 0,11046166 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,07917248 0,11039861 ! membrane budding GO:0006900 42 17 0,000 0,07917248 0,11033563 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,07917248 0,11027273 ! regulation of protein binding GO:0043393 33 17 0,000 0,07917248 0,11020989 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,07917248 0,11014713 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,07917248 0,11008444 ! genitalia development GO:0048806 32 17 0,000 0,07917248 0,11002182 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,07917248 0,10995927 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,07917248 0,1098968 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,07917248 0,10983439 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,07917248 0,10977206 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,07917248 0,10970979 ! steroid catabolic process GO:0006706 34 17 0,000 0,07917248 0,1096476 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,07917248 0,10958548 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,07917248 0,10952342 ! gas transport GO:0015669 26 17 0,000 0,07917248 0,10946144 ! organic cation transport GO:0015695 32 17 0,000 0,07917248 0,10939953 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,07917248 0,10933768 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,08047331 0,11107136 ! transcription initiation GO:0006352 171 97 1,000 0,08047331 0,11100864 ! regulation of protein localization GO:0032880 188 97 1,000 0,08047331 0,110946 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,08189765 0,112846 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,08363056 0,11516881 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,08363056 0,11510392 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08363056 0,11503911 ! limbic system development GO:0021761 40 18 0,000 0,08363056 0,11497437 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08363056 0,11490971 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08363056 0,11484512 ! adult walking behavior GO:0007628 36 18 0,000 0,08363056 0,1147806 ! patterning of blood vessels GO:0001569 43 18 0,000 0,08363056 0,11471615 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08363056 0,11465177 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,08363056 0,11458747 ! centrosome cycle GO:0007098 26 18 0,000 0,08363056 0,11452324 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,08363056 0,11445908 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08363056 0,114395 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,08363056 0,11433098 ! glycine metabolic process GO:0006544 30 18 0,000 0,08363056 0,11426704 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08363056 0,11420316 ! response to retinoic acid GO:0032526 31 18 0,000 0,08363056 0,11413936 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,08363056 0,11407563 ! DNA integration GO:0015074 32 18 0,000 0,08363056 0,11401198 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,08363056 0,11394839 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08363056 0,11388487 ! neural crest cell migration GO:0001755 41 18 0,000 0,08363056 0,11382143 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08363056 0,11375805 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,08363056 0,11369475 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08363056 0,11363151 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,08363056 0,11356835 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,08363056 0,11350526 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08363056 0,11344223 ! detection of bacterium GO:0016045 22 18 0,000 0,08363056 0,11337928 ! nerve development GO:0021675 34 18 0,000 0,08363056 0,1133164 ! defense response to virus GO:0051607 43 18 0,000 0,08363056 0,11325358 ! microspike assembly GO:0030035 46 18 0,000 0,08363056 0,11319084 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08363056 0,11312816 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,08363056 0,11306556 ! positive regulation of immune response GO:0050778 175 100 1,000 0,08476956 0,11454205 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,08806719 0,11893208 ! positive regulation of translation GO:0045727 31 19 0,000 0,08806719 0,11886637 ! negative regulation of defense response GO:0031348 27 19 0,000 0,08806719 0,11880074 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,08806719 0,11873518 ! neuron maturation GO:0042551 46 19 0,000 0,08806719 0,11866968 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,08806719 0,11860427 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,08806719 0,11853892 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,08806719 0,11847364 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,08806719 0,11840844 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,08806719 0,11834331 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08806719 0,11827825 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,08806719 0,11821326 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,08806719 0,11814835 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,08806719 0,1180835 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,08806719 0,11801873 ! cerebral cortex development GO:0021987 40 19 0,000 0,08806719 0,11795402 ! pigmentation during development GO:0048066 42 19 0,000 0,08806719 0,11788939 ! response to vitamin A GO:0033189 32 19 0,000 0,08806719 0,11782483 ! heme metabolic process GO:0042168 40 19 0,000 0,08806719 0,11776034 ! response to fungus GO:0009620 26 19 0,000 0,08806719 0,11769592 ! peptide cross-linking GO:0018149 39 19 0,000 0,08806719 0,11763157 ! protein export from nucleus GO:0006611 40 19 0,000 0,08806719 0,11756729 ! heart process GO:0003015 32 19 0,000 0,08806719 0,11750308 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,08806719 0,11743894 ! cellular pigmentation GO:0033059 37 19 0,000 0,08806719 0,11737487 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,08806719 0,11731087 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,08806719 0,11724694 ! vitamin transport GO:0051180 31 19 0,000 0,08806719 0,11718308 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,08806719 0,11711929 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,08806719 0,11705557 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,08806719 0,11699192 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,08806719 0,11692834 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,08806719 0,11686482 ! cilium assembly GO:0042384 38 19 0,000 0,08806719 0,11680138 ! peptide hormone secretion GO:0030072 32 19 0,000 0,08806719 0,116738 ! protein secretion GO:0009306 45 20 0,000 0,09248246 0,12252421 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,09248246 0,1224578 ! positive regulation of ossification GO:0045778 50 20 0,000 0,09248246 0,12239146 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,09248246 0,1223252 ! skin development GO:0043588 42 20 0,000 0,09248246 0,122259 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,09248246 0,12219288 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,09248246 0,12212683 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,09248246 0,12206085 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,09248246 0,12199495 ! response to vitamin GO:0033273 36 20 0,000 0,09248246 0,12192911 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,09248246 0,12186334 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,09248246 0,12179765 ! bile acid metabolic process GO:0008206 34 20 0,000 0,09248246 0,12173203 ! retinoid metabolic process GO:0001523 34 20 0,000 0,09248246 0,12166647 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,09248246 0,12160099 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,09248246 0,12153558 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,09248246 0,12147024 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,09248246 0,12140497 ! body fluid secretion GO:0007589 33 20 0,000 0,09248246 0,12133976 ! peptide secretion GO:0002790 38 20 0,000 0,09248246 0,12127463 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,09248246 0,12120957 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,09248246 0,12114458 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,09248246 0,12107966 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,09248246 0,1210148 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,09248246 0,12095002 ! cell-cell junction organization GO:0045216 43 20 0,000 0,09248246 0,12088531 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,09248246 0,12082066 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,09248246 0,12075609 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,09248246 0,12069158 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,09248246 0,12062714 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,09248246 0,12056277 ! regulation of glucose import GO:0046324 30 20 0,000 0,09248246 0,12049847 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,09248246 0,12043424 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,09248246 0,12037008 ! negative regulation of translation GO:0017148 32 20 0,000 0,09248246 0,12030599 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,09248246 0,12024196 ! regulation of cell killing GO:0031341 46 21 0,000 0,09687647 0,12588788 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,09687647 0,12582096 ! hormone secretion GO:0046879 39 21 0,000 0,09687647 0,1257541 ! lipid phosphorylation GO:0046834 43 21 0,000 0,09687647 0,12568732 ! cAMP metabolic process GO:0046058 41 21 0,000 0,09687647 0,12562061 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,09687647 0,12555396 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,09687647 0,12548739 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,09687647 0,12542089 ! ovarian follicle development GO:0001541 39 21 0,000 0,09687647 0,12535446 ! smooth muscle contraction GO:0006939 48 21 0,000 0,09687647 0,1252881 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,09687647 0,12522181 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,09687647 0,12515559 ! plasma membrane fusion GO:0045026 33 21 0,000 0,09687647 0,12508944 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,09687647 0,12502336 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,09687647 0,12495735 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,09687647 0,12489141 ! sensory perception of pain GO:0019233 33 21 0,000 0,09687647 0,12482554 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,09687647 0,12475974 ! diencephalon development GO:0021536 36 21 0,000 0,09687647 0,124694 ! collagen fibril organization GO:0030199 62 21 0,000 0,09687647 0,12462834 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,09687647 0,12456275 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,09687647 0,12449722 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,09687647 0,12443177 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,09687647 0,12436638 ! collagen catabolic process GO:0030574 29 21 0,000 0,09687647 0,12430106 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,09687647 0,12423581 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,09687647 0,12417063 ! sperm-egg recognition GO:0035036 23 21 0,000 0,09687647 0,12410552 ! actin filament-based movement GO:0030048 47 21 0,000 0,09687647 0,12404047 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,10124934 0,12957157 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,10124934 0,12950373 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,10124934 0,12943596 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,10124934 0,12936827 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,10124934 0,12930064 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,10124934 0,12923309 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,10124934 0,1291656 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,10124934 0,12909819 ! vacuolar transport GO:0007034 41 22 0,000 0,10124934 0,12903084 ! central nervous system neuron development GO:0021954 47 22 0,000 0,10124934 0,12896357 ! fucose metabolic process GO:0006004 44 22 0,000 0,10124934 0,12889637 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,10124934 0,12882923 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,10124934 0,12876217 ! ureteric bud development GO:0001657 50 22 0,000 0,10124934 0,12869518 ! stem cell differentiation GO:0048863 57 22 0,000 0,10124934 0,12862825 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,10124934 0,1285614 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,10124934 0,12849461 ! cytolysis GO:0019835 27 22 0,000 0,10124934 0,1284279 ! renal system process GO:0003014 42 22 0,000 0,10124934 0,12836125 ! vasodilation GO:0042311 40 22 0,000 0,10124934 0,12829467 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,10124934 0,12822816 ! G1 phase GO:0051318 44 22 0,000 0,10124934 0,12816172 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,10124934 0,12809535 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,10124934 0,12802905 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,10124934 0,12796282 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,10124934 0,12789665 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,10124934 0,12783056 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,10124934 0,12776453 ! sarcomere organization GO:0045214 32 22 0,000 0,10124934 0,12769857 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,10124934 0,12763268 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,10124934 0,12756685 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,10124934 0,1275011 ! gut development GO:0048565 44 22 0,000 0,10124934 0,12743541 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,10124934 0,12736979 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,10124934 0,12730423 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,10560115 0,13270762 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,10560115 0,13263939 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,10560115 0,13257123 ! glycerol metabolic process GO:0006071 40 23 0,000 0,10560115 0,13250314 ! viral genome replication GO:0019079 44 23 0,000 0,10560115 0,13243512 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,10560115 0,13236717 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,10560115 0,13229929 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,10560115 0,13223147 ! regeneration GO:0031099 42 23 0,000 0,10560115 0,13216373 ! axis specification GO:0009798 43 23 0,000 0,10560115 0,13209606 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,10560115 0,13202846 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,10560115 0,13196092 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,10560115 0,13189346 ! peroxisome organization GO:0007031 43 23 0,000 0,10560115 0,13182606 ! lysosome organization GO:0007040 47 23 0,000 0,10560115 0,13175874 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,10560115 0,13169148 ! vesicle targeting GO:0006903 49 23 0,000 0,10560115 0,13162429 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,10560115 0,13155717 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,10560115 0,13149012 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,10560115 0,13142313 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,10560115 0,13135622 ! DNA modification GO:0006304 36 23 0,000 0,10560115 0,13128937 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,10560115 0,13122259 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,10560115 0,13115588 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,10560115 0,13108923 ! hormone transport GO:0009914 41 23 0,000 0,10560115 0,13102265 ! cell-cell recognition GO:0009988 28 23 0,000 0,10560115 0,13095615 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,10560115 0,1308897 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,10560115 0,13082333 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,10993201 0,13611957 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,10993201 0,13605061 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,10993201 0,13598173 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,10993201 0,13591291 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,10993201 0,13584416 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,10993201 0,13577548 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,10993201 0,13570688 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,10993201 0,13563834 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,10993201 0,13556987 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,10993201 0,13550147 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,10993201 0,13543314 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,10993201 0,13536487 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,10993201 0,13529668 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,10993201 0,13522855 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,10993201 0,1351605 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,10993201 0,13509251 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,10993201 0,13502459 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,10993201 0,13495674 ! pallium development GO:0021543 56 24 0,000 0,10993201 0,13488895 ! oogenesis GO:0048477 44 24 0,000 0,10993201 0,13482124 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,10993201 0,13475359 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,10993201 0,13468601 ! platelet activation GO:0030168 41 24 0,000 0,10993201 0,1346185 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,10993201 0,13455106 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,10993201 0,13448368 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,10993201 0,13441637 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,10993201 0,13434913 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,10993201 0,13428195 ! regulation of amine transport GO:0051952 41 24 0,000 0,10993201 0,13421485 ! leukocyte adhesion GO:0007159 55 25 0,000 0,11424203 0,13940723 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,11424203 0,13933763 ! phototransduction GO:0007602 37 25 0,000 0,11424203 0,1392681 ! keratinization GO:0031424 37 25 0,000 0,11424203 0,13919864 ! vacuole organization GO:0007033 49 25 0,000 0,11424203 0,13912925 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,11424203 0,13905993 ! chromosome condensation GO:0030261 48 25 0,000 0,11424203 0,13899067 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,11424203 0,13892149 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,11424203 0,13885237 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,11424203 0,13878333 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,11424203 0,13871435 ! immunoglobulin production GO:0002377 62 25 0,000 0,11424203 0,13864544 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,11424203 0,1385766 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,11424203 0,13850783 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,11424203 0,13843912 ! liver development GO:0001889 55 25 0,000 0,11424203 0,13837049 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,11853129 0,14349452 ! initiation of viral infection GO:0019059 60 26 0,000 0,11853129 0,14342345 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,11853129 0,14335245 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,11853129 0,14328152 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,11853129 0,14321065 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,11853129 0,14313986 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,11853129 0,14306914 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,11853129 0,14299849 ! digestive system process GO:0022600 49 26 0,000 0,11853129 0,14292791 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,11853129 0,1428574 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,11853129 0,14278695 ! osteoblast differentiation GO:0001649 63 26 0,000 0,11853129 0,14271658 ! neural crest cell development GO:0014032 59 26 0,000 0,11853129 0,14264628 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,11853129 0,14257604 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,11853129 0,14250588 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,11853129 0,14243578 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,11853129 0,14236575 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,11853129 0,1422958 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,11853129 0,14222591 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,11853129 0,14215608 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,11853129 0,14208633 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,11853129 0,14201665 ! telomere organization GO:0032200 46 26 0,000 0,11853129 0,14194703 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,11853129 0,14187748 ! neural tube closure GO:0001843 58 26 0,000 0,11853129 0,141808 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,11853129 0,14173859 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,11853129 0,14166925 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,11853129 0,14159997 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1227999 0,14662765 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1227999 0,14655602 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,1227999 0,14648446 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,1227999 0,14641297 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1227999 0,14634154 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1227999 0,14627019 ! iron ion transport GO:0006826 65 27 0,000 0,1227999 0,14619891 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1227999 0,1461277 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1227999 0,14605656 ! tube lumen formation GO:0035148 59 27 0,000 0,1227999 0,14598548 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1227999 0,14591448 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1227999 0,14584354 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1227999 0,14577268 ! leukocyte proliferation GO:0070661 59 27 0,000 0,1227999 0,14570188 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,12704797 0,15066902 ! vesicle docking GO:0048278 55 28 0,000 0,12704797 0,15059592 ! circadian rhythm GO:0007623 56 28 0,000 0,12704797 0,15052288 ! dendrite development GO:0016358 67 28 0,000 0,12704797 0,15044992 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,12704797 0,15037703 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,12704797 0,1503042 ! sperm motility GO:0030317 37 28 0,000 0,12704797 0,15023145 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,12704797 0,15015877 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,12704797 0,15008616 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,12704797 0,15001362 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,12704797 0,14994115 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,12704797 0,14986875 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,12704797 0,14979642 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,12704797 0,14972416 ! glutathione metabolic process GO:0006749 42 28 0,000 0,12704797 0,14965197 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,12704797 0,14957985 ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,12704797 0,14950779 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,12704797 0,14943581 ! translational initiation GO:0006413 66 29 0,000 0,13127557 0,15433409 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,13127557 0,15425985 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,13127557 0,15418569 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,13127557 0,1541116 ! primary neural tube formation GO:0014020 61 29 0,000 0,13127557 0,15403757 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,13127557 0,15396362 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,13127557 0,15388975 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,13127557 0,15381594 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,13127557 0,1537422 ! synaptogenesis GO:0007416 46 29 0,000 0,13127557 0,15366853 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,13127557 0,15359494 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,13127557 0,15352141 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,13127557 0,15344796 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,13127557 0,15337457 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,13548283 0,15821441 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,13548283 0,15813882 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,13548283 0,1580633 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,13548283 0,15798785 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,13548283 0,15791248 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,13548283 0,15783717 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,13548283 0,15776194 ! acute-phase response GO:0006953 50 30 0,000 0,13548283 0,15768678 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,13548283 0,15761169 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,13548283 0,15753667 ! myofibril assembly GO:0030239 50 30 0,000 0,13548283 0,15746173 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,13548283 0,15738685 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,13548283 0,15731205 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,13548283 0,15723732 ! phospholipid transport GO:0015914 65 30 0,000 0,13548283 0,15716265 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,13548283 0,15708806 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,13548283 0,15701354 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,13548283 0,15693909 ! tissue homeostasis GO:0001894 50 30 0,000 0,13548283 0,15686472 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,13548283 0,15679041 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,13966982 0,16155937 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,13966982 0,16148291 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,13966982 0,16140652 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,13966982 0,1613302 ! regulation of innate immune response GO:0045088 57 31 0,000 0,13966982 0,16125396 ! ovulation cycle process GO:0022602 55 31 0,000 0,13966982 0,16117779 ! peptide transport GO:0015833 60 31 0,000 0,13966982 0,16110169 ! male gonad development GO:0008584 56 31 0,000 0,13966982 0,16102566 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,13966982 0,16094971 ! detection of light stimulus GO:0009583 44 31 0,000 0,13966982 0,16087382 ! natural killer cell activation GO:0030101 50 31 0,000 0,13966982 0,16079801 ! cofactor catabolic process GO:0051187 54 31 0,000 0,13966982 0,16072227 ! eye morphogenesis GO:0048592 65 31 0,000 0,13966982 0,1606466 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,13966982 0,160571 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,14383666 0,16528361 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,14383666 0,1652059 ! collagen metabolic process GO:0032963 49 32 0,000 0,14383666 0,16512827 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,14383666 0,16505071 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,14383666 0,16497322 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,14383666 0,1648958 ! metanephros development GO:0001656 81 32 0,000 0,14383666 0,16481846 ! muscle cell development GO:0055001 52 32 0,000 0,14383666 0,16474119 ! mesoderm formation GO:0001707 73 32 0,000 0,14383666 0,16466399 ! ovulation cycle GO:0042698 57 32 0,000 0,14383666 0,16458686 ! BMP signaling pathway GO:0030509 71 32 0,000 0,14383666 0,16450981 ! hindbrain development GO:0030902 65 32 0,000 0,14383666 0,16443283 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,14383666 0,16435592 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,14383666 0,16427908 ! gene silencing GO:0016458 71 32 0,000 0,14383666 0,16420232 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,14798343 0,16885732 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,14798343 0,16877848 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,14798343 0,16869973 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,14798343 0,16862104 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,14798343 0,16854243 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,14798343 0,16846389 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,14798343 0,16838543 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,14798343 0,16830704 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,14798343 0,16822872 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,14798343 0,16815047 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,15211023 0,17275932 ! glial cell differentiation GO:0010001 67 34 0,000 0,15211023 0,17267904 ! post-embryonic development GO:0009791 76 34 0,000 0,15211023 0,17259883 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,15211023 0,17251871 ! cholesterol transport GO:0030301 62 34 0,000 0,15211023 0,17243865 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,15211023 0,17235867 ! spliceosome assembly GO:0000245 75 34 0,000 0,15211023 0,17227876 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,15211023 0,17219893 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,15211023 0,17211917 ! formation of primary germ layer GO:0001704 76 34 0,000 0,15211023 0,17203949 ! cell fate specification GO:0001708 56 34 0,000 0,15211023 0,17195988 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,15211023 0,17188034 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,15211023 0,17180087 ! adult locomotory behavior GO:0008344 62 34 0,000 0,15211023 0,17172148 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,15621716 0,17627645 ! negative regulation of secretion GO:0051048 68 35 0,000 0,15621716 0,17619507 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,15621716 0,17611376 ! membrane docking GO:0022406 69 35 0,000 0,15621716 0,17603253 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,15621716 0,17595137 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,15621716 0,17587028 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,15621716 0,17578928 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,15621716 0,17570834 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,15621716 0,17562748 ! ceramide metabolic process GO:0006672 72 35 0,000 0,15621716 0,1755467 ! telencephalon development GO:0021537 81 35 0,000 0,15621716 0,17546599 ! sterol transport GO:0015918 63 35 0,000 0,15621716 0,17538535 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,15621716 0,17530479 ! vesicle localization GO:0051648 70 35 0,000 0,15621716 0,1752243 ! regulation of muscle development GO:0048634 82 36 0,000 0,16030431 0,17972622 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,16030431 0,17964377 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,16030431 0,17956141 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,16030431 0,17947911 ! positive regulation of cell development GO:0010720 85 36 0,000 0,16030431 0,1793969 ! protein targeting to membrane GO:0006612 75 36 0,000 0,16030431 0,17931476 ! regulation of proteolysis GO:0030162 77 36 0,000 0,16030431 0,17923269 ! aerobic respiration GO:0009060 56 36 0,000 0,16030431 0,1791507 ! cytokine production GO:0001816 68 36 0,000 0,16030431 0,17906878 ! embryonic organ development GO:0048568 67 36 0,000 0,16030431 0,17898694 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,16030431 0,17890517 ! odontogenesis GO:0042476 74 37 0,000 0,16437178 0,18336085 ! actomyosin structure organization GO:0031032 68 37 0,000 0,16437178 0,18327716 ! female gonad development GO:0008585 71 37 0,000 0,16437178 0,18319355 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,16437178 0,18311001 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,16841966 0,18753383 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,16841966 0,18744839 ! organic anion transport GO:0015711 82 38 0,000 0,16841966 0,18736303 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,16841966 0,18727775 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,16841966 0,18719255 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,16841966 0,18710742 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,16841966 0,18702237 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,16841966 0,1869374 ! spermatid development GO:0007286 69 38 0,000 0,16841966 0,18685251 ! glycogen metabolic process GO:0005977 63 38 0,000 0,16841966 0,18676769 ! pigment metabolic process GO:0042440 87 38 0,000 0,16841966 0,18668295 ! neural tube formation GO:0001841 79 38 0,000 0,16841966 0,18659829 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,17244804 0,19097487 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,17244804 0,19088834 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,17244804 0,19080189 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,17244804 0,19071551 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,17244804 0,19062922 ! glucan metabolic process GO:0044042 64 39 0,000 0,17244804 0,190543 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,17645702 0,1948845 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,17645702 0,19479643 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,17645702 0,19470845 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 0,000 0,17645702 0,19462055 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,17645702 0,19453272 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,17645702 0,19444498 ! mRNA catabolic process GO:0006402 79 41 0,000 0,1804467 0,19875171 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,1804467 0,19866214 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,1804467 0,19857265 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,1804467 0,19848324 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,1804467 0,19839392 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,1804467 0,19830467 ! gliogenesis GO:0042063 91 41 0,000 0,1804467 0,19821551 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,1804467 0,19812642 ! mesenchymal cell development GO:0014031 94 41 0,000 0,1804467 0,19803741 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,1804467 0,19794849 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,1804467 0,19785964 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,1804467 0,19777088 ! RNA modification GO:0009451 64 41 0,000 0,1804467 0,19768219 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,18441716 0,20194133 ! organic ether metabolic process GO:0018904 59 42 0,000 0,18441716 0,20185086 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,18441716 0,20176046 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,18441716 0,20167015 ! regulation of protein secretion GO:0050708 77 42 0,000 0,18441716 0,20157992 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,18441716 0,20148976 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,18836849 0,2057149 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,18836849 0,20562298 ! regulation of tube size GO:0035150 76 43 0,000 0,18836849 0,20553114 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,18836849 0,20543938 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,18836849 0,20534771 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,18836849 0,20525612 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,18836849 0,20516461 ! ion transmembrane transport GO:0034220 79 43 0,000 0,18836849 0,20507318 ! neuron migration GO:0001764 85 43 0,000 0,18836849 0,20498184 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,18836849 0,20489057 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,19230079 0,20907469 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,19230079 0,20898169 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,19230079 0,20888877 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,19230079 0,20879593 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,19230079 0,20870317 ! striated muscle contraction GO:0006941 85 44 0,000 0,19230079 0,20861049 ! phagocytosis GO:0006909 105 44 0,000 0,19230079 0,2085179 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,19230079 0,20842539 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,19621415 0,21257258 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,19621415 0,21247836 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,19621415 0,21238421 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,19621415 0,21229016 ! biopolymer methylation GO:0043414 91 45 0,000 0,19621415 0,21219618 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,19621415 0,21210229 ! female gamete generation GO:0007292 71 45 0,000 0,19621415 0,21200848 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,19621415 0,21191475 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,20010866 0,21602539 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,20010866 0,21592997 ! glycolysis GO:0006096 71 46 0,000 0,20010866 0,21583464 ! leukocyte migration GO:0050900 75 46 0,000 0,20010866 0,21573939 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,20010866 0,21564422 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,20010866 0,21554914 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,20010866 0,21545415 ! neural tube development GO:0021915 91 47 0,000 0,20398441 0,21953036 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,20398441 0,21943369 ! positive regulation of defense response GO:0031349 88 48 0,000 0,20784149 0,22348448 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,20784149 0,22338616 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,20784149 0,22328793 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,20784149 0,22318978 ! male sex differentiation GO:0046661 93 48 0,000 0,20784149 0,22309172 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,20784149 0,22299374 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,20784149 0,22289585 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,20784149 0,22279805 ! methylation GO:0032259 97 48 0,000 0,20784149 0,22270033 ! response to calcium ion GO:0051592 94 49 0,000 0,21167998 0,22671381 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,21167998 0,22661446 ! protein homooligomerization GO:0051260 84 49 0,000 0,21167998 0,2265152 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,21549999 0,23050195 ! regulation of ossification GO:0030278 123 50 0,000 0,21549999 0,23040108 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,21549999 0,23030029 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,21549999 0,23019959 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,21549999 0,23009898 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,21549999 0,22999846 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,21549999 0,22989802 ! viral infectious cycle GO:0019058 104 51 0,000 0,21930159 0,23385149 ! peptide metabolic process GO:0006518 80 51 0,000 0,21930159 0,23374947 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,22308487 0,2376783 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,22308487 0,23757469 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,22308487 0,23747117 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,22308487 0,23736774 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,22308487 0,23726441 ! excretion GO:0007588 87 52 0,000 0,22308487 0,23716116 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,22308487 0,237058 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,22308487 0,23695493 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,22308487 0,23685195 ! amino acid activation GO:0043038 98 52 0,000 0,22308487 0,23674906 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,22684993 0,2406402 ! inner ear development GO:0048839 89 53 0,000 0,22684993 0,24053575 ! chromatin remodeling GO:0006338 122 53 0,000 0,22684993 0,2404314 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,22684993 0,24032714 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,22684993 0,24022296 ! vesicle organization GO:0016050 127 53 0,000 0,22684993 0,24011888 ! cartilage development GO:0051216 99 53 0,000 0,22684993 0,24001489 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,23059684 0,24387363 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,23059684 0,2437681 ! membrane fusion GO:0006944 122 54 0,000 0,23059684 0,24366267 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,23059684 0,24355732 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,23059684 0,24345207 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,23059684 0,24334691 ! RNA catabolic process GO:0006401 103 55 0,000 0,23432571 0,24717517 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,23432571 0,24706849 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,23432571 0,24696191 ! cell recognition GO:0008037 98 55 0,000 0,23432571 0,24685541 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,23432571 0,24674901 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,23432571 0,2466427 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,23432571 0,24653648 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,2380366 0,25033294 ! glucose catabolic process GO:0006007 88 56 0,000 0,2380366 0,25022522 ! RNA elongation GO:0006354 90 56 0,000 0,2380366 0,2501176 ! chloride transport GO:0006821 102 57 0,000 0,24172962 0,25388885 ! regulation of actin filament length GO:0030832 118 58 0,000 0,24540484 0,25763817 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,24540484 0,2575275 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,24540484 0,25741692 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,24540484 0,25730644 ! gastrulation GO:0007369 122 58 0,000 0,24540484 0,25719606 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,24540484 0,25708577 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,25270223 0,26461704 ! regulation of endocytosis GO:0030100 104 60 0,000 0,25270223 0,26450366 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,25270223 0,26439038 ! adult behavior GO:0030534 104 60 0,000 0,25270223 0,2642772 ! kidney development GO:0001822 133 60 0,000 0,25270223 0,26416412 ! positive regulation of secretion GO:0051047 110 61 0,000 0,25632457 0,26783616 ! regulation of cellular component size GO:0032535 125 61 0,000 0,25632457 0,26772165 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,25632457 0,26760724 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,25632457 0,26749292 ! camera-type eye development GO:0043010 126 61 0,000 0,25632457 0,26737871 ! proton transport GO:0015992 117 61 0,000 0,25632457 0,26726459 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,25632457 0,26715057 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,25992946 0,27079218 ! tRNA processing GO:0008033 102 62 0,000 0,25992946 0,27067676 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,26351697 0,27429568 ! mesoderm development GO:0007498 128 63 0,000 0,26351697 0,27417886 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,26351697 0,27406214 ! hydrogen transport GO:0006818 121 64 0,000 0,26708719 0,27765703 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,26708719 0,27753893 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,27064021 0,28111141 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,27064021 0,28099194 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,27064021 0,28087257 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,27064021 0,28075331 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,2741761 0,2843006 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,2741761 0,28417998 ! gonad development GO:0008406 115 66 0,000 0,2741761 0,28405946 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,27769495 0,2875832 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,27769495 0,28746134 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,27769495 0,28733959 ! secondary metabolic process GO:0019748 125 67 0,000 0,27769495 0,28721794 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,28119684 0,29071683 ! hexose catabolic process GO:0019320 113 68 0,000 0,28119684 0,29059386 ! extracellular matrix organization GO:0030198 146 68 0,000 0,28119684 0,29047098 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,28119684 0,29034821 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,28119684 0,29022555 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,28468185 0,29369837 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,28468185 0,2935744 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,28468185 0,29345053 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,28468185 0,29332676 ! single fertilization GO:0007338 83 69 0,000 0,28468185 0,2932031 ! cell redox homeostasis GO:0045454 114 70 0,000 0,28815006 0,29665006 ! germ cell development GO:0007281 133 70 0,000 0,28815006 0,2965251 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,29160155 0,29995056 ! appendage morphogenesis GO:0035107 150 72 0,000 0,2950364 0,30335603 GO:0035108|limb morphogenesis, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,2950364 0,30322841 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,2950364 0,30310089 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,2950364 0,30297349 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,2950364 0,30284619 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,2950364 0,30271899 ! appendage development GO:0048736 151 73 0,000 0,29845469 0,30609774 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,29845469 0,30596929 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,29845469 0,30584095 ! regulation of immune effector process GO:0002697 156 73 0,000 0,29845469 0,30571271 ! acute inflammatory response GO:0002526 118 74 0,000 0,30185651 0,30906767 ! amino acid transport GO:0006865 148 74 0,000 0,30185651 0,30893819 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,30185651 0,30880882 ! transition metal ion transport GO:0000041 143 75 0,000 0,30524192 0,31214149 ! eye development GO:0001654 155 75 0,000 0,30524192 0,31201089 ! rhythmic process GO:0048511 142 75 0,000 0,30524192 0,31188039 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,30861102 0,31519093 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,30861102 0,31505922 ! amine catabolic process GO:0009310 136 77 0,000 0,31196387 0,31834909 ! neurotransmitter transport GO:0006836 142 77 0,000 0,31196387 0,31821617 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,31196387 0,31808336 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,31196387 0,31795066 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,31196387 0,31781807 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,31196387 0,31768559 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,31196387 0,31755322 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,31530055 0,32081602 ! antigen processing and presentation GO:0019882 117 78 0,000 0,31530055 0,32068245 ! fertilization GO:0009566 99 78 0,000 0,31530055 0,320549 ! blood coagulation GO:0007596 151 79 0,000 0,31862115 0,32379013 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,31862115 0,3236555 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,31862115 0,32352098 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,32192574 0,32674058 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,32192574 0,32660489 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,32192574 0,32646931 ! muscle cell differentiation GO:0042692 178 81 0,000 0,32521439 0,32966753 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,32521439 0,3295308 ! exocytosis GO:0006887 153 83 0,000 0,3317442 0,33600791 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,3317442 0,33586866 ! inorganic anion transport GO:0015698 156 83 0,000 0,3317442 0,33572953 ! response to metal ion GO:0010038 158 84 0,000 0,33498551 0,3388694 ! digestion GO:0007586 130 84 0,000 0,33498551 0,33872913 ! hemostasis GO:0007599 165 85 0,000 0,33821118 0,34184937 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,33821118 0,34170799 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,34461594 0,34803503 ! alcohol catabolic process GO:0046164 142 87 0,000 0,34461594 0,34789122 ! nucleosome assembly GO:0006334 126 87 0,000 0,34461594 0,34774752 ! cellular respiration GO:0045333 143 88 0,000 0,34779518 0,35081074 ! amine biosynthetic process GO:0009309 146 88 0,000 0,34779518 0,35066596 ! sensory perception of smell GO:0007608 117 88 0,000 0,34779518 0,35052129 ! chromatin assembly GO:0031497 128 88 0,000 0,34779518 0,35037675 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,34779518 0,35023232 ! tube morphogenesis GO:0035239 194 89 0,000 0,35095908 0,35327277 ! cellular defense response GO:0006968 123 89 0,000 0,35095908 0,35312727 ! response to inorganic substance GO:0010035 173 90 0,000 0,35410772 0,35614868 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,35410772 0,35600212 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,35410772 0,35585568 ! defense response to bacterium GO:0042742 112 91 0,000 0,35724117 0,35885698 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,36035951 0,36184064 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,36346281 0,36480676 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,36346281 0,36465694 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,36655114 0,36760445 ! regulation of defense response GO:0031347 171 95 0,000 0,36962457 0,3705346 ! nucleosome organization GO:0034728 143 95 0,000 0,36962457 0,37038262 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,36962457 0,37023076 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,36962457 0,37007903 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,36962457 0,36992742 ! forebrain development GO:0030900 210 98 0,000 0,3787562 0,3789113 ! hormone metabolic process GO:0042445 171 100 0,000 0,38477077 0,38477077