pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6630-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 93 45 6,000 2,082E-08 5,008E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 6,000 2,441E-08 2,937E-05 ! response to UV GO:0009411 104 53 6,000 6,755E-08 5,418E-05 ! regulation of DNA metabolic process GO:0051052 178 97 7,000 3,209E-07 1,931E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 3,519E-07 1,693E-04 ! negative regulation of kinase activity GO:0033673 131 68 6,000 3,901E-07 1,564E-04 ! sex determination GO:0007530 47 23 4,000 4,037E-07 1,388E-04 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 5,072E-07 1,525E-04 ! negative regulation of transferase activity GO:0051348 140 72 6,000 5,794E-07 1,549E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 7,764E-07 1,868E-04 GO:0045936|negative regulation of phosphate metabolic process, ! C21-steroid hormone biosynthetic process GO:0006700 23 15 3,000 2,581E-06 5,645E-04 ! negative regulation of DNA metabolic process GO:0051053 61 35 4,000 3,647E-06 7,312E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 6,000 3,814E-06 7,058E-04 ! interphase GO:0051325 213 98 6,000 4,694E-06 8,067E-04 ! cell cycle arrest GO:0007050 213 100 6,000 5,37E-06 8,614E-04 ! C21-steroid hormone metabolic process GO:0008207 33 20 3,000 8,921E-06 1,342E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 8,921E-06 1,263E-03 ! regulation of helicase activity GO:0051095 15 7 2,000 1,035E-05 1,384E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 1,035E-05 1,311E-03 ! inactivation of MAPK activity GO:0000188 39 21 3,000 1,096E-05 1,319E-03 ! apoptotic nuclear changes GO:0030262 32 22 3,000 1,333E-05 1,527E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 1,648E-05 1,803E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,648E-05 1,724E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,648E-05 1,652E-03 ! negative regulation of DNA replication GO:0008156 42 25 3,000 2,269E-05 2,183E-03 ! induction of positive chemotaxis GO:0050930 15 9 2,000 2,46E-05 2,276E-03 ! motor axon guidance GO:0008045 16 9 2,000 2,46E-05 2,192E-03 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 2,667E-05 2,292E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 3,114E-05 2,584E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 3,497E-05 2,804E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 3,497E-05 2,714E-03 ! regulation of DNA replication GO:0006275 101 56 4,000 3,826E-05 2,877E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 4,171E-05 3,041E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 4,784E-05 3,385E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 4,784E-05 3,289E-03 GO:0010829|negative regulation of glucose transport, ! T cell receptor signaling pathway GO:0050852 23 11 2,000 4,784E-05 3,197E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 3,000 6,215E-05 4,041E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 6,347E-05 4,019E-03 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 6,347E-05 3,916E-03 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 6,347E-05 3,818E-03 GO:0042130|negative regulation of T cell proliferation, ! response to X-ray GO:0010165 25 13 2,000 8,21E-05 4,818E-03 ! actin filament organization GO:0007015 148 66 4,000 8,477E-05 4,856E-03 ! negative regulation of cell growth GO:0030308 132 67 4,000 9,11E-05 5,098E-03 ! hormone biosynthetic process GO:0042446 57 36 3,000 9,968E-05 5,451E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 1,04E-04 5,559E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 1,04E-04 5,438E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 1,049E-04 5,368E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 1,049E-04 5,256E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 1,112E-04 5,459E-03 ! nucleus organization GO:0006997 67 38 3,000 1,236E-04 5,948E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,293E-04 6,101E-03 ! protein polyubiquitination GO:0000209 34 16 2,000 1,584E-04 7,328E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,584E-04 7,19E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! T cell differentiation GO:0030217 81 41 3,000 1,669E-04 7,437E-03 ! signal complex assembly GO:0007172 41 17 2,000 1,914E-04 8,371E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,914E-04 8,222E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,914E-04 8,078E-03 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 2,000 1,914E-04 7,938E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 1,992E-04 8,122E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 2,24E-04 8,981E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to insulin stimulus GO:0032868 95 46 3,000 2,62E-04 0,01033389 ! negative regulation of growth GO:0045926 155 84 4,000 2,655E-04 0,01030276 ! proximal/distal pattern formation GO:0009954 32 19 2,000 2,7E-04 0,01031128 ! activation of caspase activity GO:0006919 84 48 3,000 3,091E-04 0,01162162 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 3,091E-04 0,01144282 ! regulation of glucose import GO:0046324 29 20 2,000 3,161E-04 0,01152212 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 3,161E-04 0,01135015 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 3,669E-04 0,01298246 ! positive regulation of locomotion GO:0040017 39 21 2,000 3,669E-04 0,01279431 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 3,669E-04 0,01261153 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 3,908E-04 0,01324379 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of chemotaxis GO:0050920 40 22 2,000 4,227E-04 0,01412687 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 4,227E-04 0,01393335 ! cellular response to reactive oxygen species GO:0034614 31 22 2,000 4,227E-04 0,01374507 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 4,227E-04 0,0135618 ! positive regulation of helicase activity GO:0051096 11 5 1,000 4,461E-04 0,01412256 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 4,461E-04 0,01393915 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 4,461E-04 0,01376044 ! epithelial cell proliferation GO:0050673 9 5 1,000 4,461E-04 0,01358626 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 4,461E-04 0,01341643 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 4,461E-04 0,01325079 ! microvillus organization GO:0032528 7 5 1,000 4,461E-04 0,0130892 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,461E-04 0,0129315 ! peptidyl-histidine phosphorylation GO:0018106 9 5 1,000 4,461E-04 0,01277755 ! early endosome to late endosome transport GO:0045022 12 5 1,000 4,461E-04 0,01262723 ! stem cell division GO:0017145 11 5 1,000 4,461E-04 0,0124804 GO:0048103|somatic stem cell division, ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 2,000 4,838E-04 0,01337831 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! positive regulation of caspase activity GO:0043280 95 55 3,000 5,223E-04 0,01427998 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 3,000 5,223E-04 0,01411953 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 5,501E-04 0,01470669 ! regulation of behavior GO:0050795 43 24 2,000 5,501E-04 0,01454508 ! nucleotide-excision repair GO:0006289 83 56 3,000 5,595E-04 0,01463284 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 6,22E-04 0,01609301 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 6,22E-04 0,01592181 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 1,000 6,662E-04 0,01687178 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 6,662E-04 0,01669603 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 6,662E-04 0,01652391 ! determination of adult lifespan GO:0008340 15 6 1,000 6,662E-04 0,0163553 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 6,662E-04 0,01619009 ! negative regulation of B cell activation GO:0050869 13 6 1,000 6,662E-04 0,01602819 ! DNA catabolic process GO:0006308 86 59 3,000 6,825E-04 0,01625868 ! integrin-mediated signaling pathway GO:0007229 135 59 3,000 6,825E-04 0,01609928 ! cellular response to oxidative stress GO:0034599 39 26 2,000 6,997E-04 0,01634462 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 7,744E-04 0,01791591 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 7,833E-04 0,01794825 ! base-excision repair GO:0006284 41 27 2,000 7,833E-04 0,01777893 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 7,833E-04 0,01761277 ! negative regulation of protein modification process GO:0031400 60 28 2,000 8,729E-04 0,01944703 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 8,729E-04 0,01926862 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 9,285E-04 0,02030894 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 9,285E-04 0,02012598 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 9,285E-04 0,01994628 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 9,285E-04 0,01976976 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 9,285E-04 0,01959635 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 9,285E-04 0,01942594 ! B cell lineage commitment GO:0002326 21 7 1,000 9,285E-04 0,01925848 ! T cell lineage commitment GO:0002360 16 7 1,000 9,285E-04 0,01909387 ! response to tumor cell GO:0002347 13 7 1,000 9,285E-04 0,01893206 ! peptidyl-histidine modification GO:0018202 16 7 1,000 9,285E-04 0,01877297 ! immune response-activating signal transduction GO:0002757 47 29 2,000 9,688E-04 0,01942535 GO:0002764|immune response-regulating signal transduction, ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 9,688E-04 0,01926481 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 9,688E-04 0,0191069 ! embryonic limb morphogenesis GO:0030326 125 65 3,000 9,839E-04 0,01924564 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 3,000 9,839E-04 0,01909043 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 1,071E-03 0,020618 ! regulation of B cell activation GO:0050864 50 30 2,000 1,071E-03 0,02045437 ! cellular hormone metabolic process GO:0034754 113 67 3,000 1,102E-03 0,02088207 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 1,102E-03 0,02071893 ! erythrocyte differentiation GO:0030218 55 31 2,000 1,18E-03 0,02201001 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 1,18E-03 0,0218407 GO:0043433|negative regulation of transcription factor activity, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 1,000 1,233E-03 0,02263684 GO:0016446|somatic hypermutation of immunoglobulin genes, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,233E-03 0,02246535 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,233E-03 0,02229644 ! ER overload response GO:0006983 12 8 1,000 1,233E-03 0,02213005 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,233E-03 0,02196612 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,233E-03 0,0218046 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 1,000 1,233E-03 0,02164545 ! DNA topological change GO:0006265 12 8 1,000 1,233E-03 0,0214886 ! multicellular organismal aging GO:0010259 18 8 1,000 1,233E-03 0,021334 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 1,233E-03 0,02118162 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 1,233E-03 0,02103139 GO:0000076|DNA replication checkpoint, ! response to ionizing radiation GO:0010212 65 32 2,000 1,296E-03 0,02195452 ! appendage morphogenesis GO:0035107 135 70 3,000 1,298E-03 0,02183954 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 3,000 1,368E-03 0,0228628 GO:0060173|limb development, ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,418E-03 0,02353358 GO:0060326|cell chemotaxis, ! regulation of caspase activity GO:0043281 122 72 3,000 1,441E-03 0,02375156 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 1,441E-03 0,02358998 ! microtubule bundle formation GO:0001578 21 9 1,000 1,578E-03 0,02564716 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,578E-03 0,02547504 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 1,578E-03 0,0253052 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,578E-03 0,02513762 ! receptor clustering GO:0043113 18 9 1,000 1,578E-03 0,02497224 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,578E-03 0,02480902 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,578E-03 0,02464792 ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,595E-03 0,02476172 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,595E-03 0,02460299 ! cell-matrix adhesion GO:0007160 163 75 3,000 1,676E-03 0,02568896 ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 1,676E-03 0,02552638 ! lymphocyte differentiation GO:0030098 167 75 3,000 1,676E-03 0,02536583 ! regulation of microtubule-based process GO:0032886 78 35 2,000 1,685E-03 0,02533236 ! steroid biosynthetic process GO:0006694 131 76 3,000 1,76E-03 0,02630467 ! DNA integrity checkpoint GO:0031570 75 36 2,000 1,829E-03 0,02715953 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,829E-03 0,02699291 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,829E-03 0,02682832 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,963E-03 0,02862844 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,963E-03 0,02845598 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,963E-03 0,02828558 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,963E-03 0,02811722 ! DNA ligation GO:0006266 19 10 1,000 1,963E-03 0,02795084 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 1,963E-03 0,02778643 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 1,963E-03 0,02762393 ! detection of calcium ion GO:0005513 23 10 1,000 1,963E-03 0,02746333 ! localization within membrane GO:0051668 20 10 1,000 1,963E-03 0,02730458 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,98E-03 0,02738197 ! regulation of protein stability GO:0031647 73 37 2,000 1,98E-03 0,0272255 ! glycogen metabolic process GO:0005977 61 37 2,000 1,98E-03 0,02707081 ! regulation of peptidase activity GO:0052547 134 79 3,000 2,029E-03 0,02758537 ! erythrocyte homeostasis GO:0034101 64 38 2,000 2,139E-03 0,02891772 ! glucan metabolic process GO:0044042 62 38 2,000 2,139E-03 0,02875617 GO:0006073|cellular glucan metabolic process, ! T cell activation GO:0042110 168 81 3,000 2,224E-03 0,02972469 ! cell-substrate adhesion GO:0031589 171 81 3,000 2,224E-03 0,02956047 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 2,326E-03 0,03074483 ! negative regulation of muscle development GO:0048635 20 11 1,000 2,389E-03 0,03140887 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,389E-03 0,03123817 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,389E-03 0,03106931 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 2,389E-03 0,03090227 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,389E-03 0,03073702 ! regulation of intracellular pH GO:0051453 19 11 1,000 2,389E-03 0,03057352 ! DNA methylation GO:0006306 19 11 1,000 2,389E-03 0,03041176 GO:0006305|DNA alkylation, ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 2,389E-03 0,0302517 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! negative regulation of binding GO:0051100 72 40 2,000 2,481E-03 0,03125232 ! negative regulation of transport GO:0051051 153 84 3,000 2,539E-03 0,03181651 ! regulation of T cell proliferation GO:0042129 71 41 2,000 2,664E-03 0,0332059 ! regulation of T cell differentiation GO:0045580 70 41 2,000 2,664E-03 0,03303474 ! mitochondrion organization GO:0007005 148 86 3,000 2,765E-03 0,03412006 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,854E-03 0,03503492 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,854E-03 0,03485708 ! focal adhesion formation GO:0048041 35 12 1,000 2,854E-03 0,03468103 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 2,854E-03 0,03450676 ! histone acetylation GO:0016573 26 12 1,000 2,854E-03 0,03433422 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,854E-03 0,0341634 ! response to reactive oxygen species GO:0000302 67 42 2,000 2,854E-03 0,03399877 ! positive regulation of protein modification process GO:0031401 136 88 3,000 3,005E-03 0,03561779 ! regulation of DNA binding GO:0051101 155 88 3,000 3,005E-03 0,0354432 ! energy reserve metabolic process GO:0006112 74 43 2,000 3,053E-03 0,03583664 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 3,053E-03 0,03566267 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,053E-03 0,03549039 ! double-strand break repair GO:0006302 81 44 2,000 3,261E-03 0,03771771 ! regulation of DNA repair GO:0006282 21 13 1,000 3,358E-03 0,03865763 ! regulation of cellular pH GO:0030641 22 13 1,000 3,358E-03 0,03847355 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,358E-03 0,03829121 ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 3,358E-03 0,03811059 ! actin filament polymerization GO:0030041 24 13 1,000 3,358E-03 0,03793167 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 3,358E-03 0,03775442 ! Golgi organization GO:0007030 24 13 1,000 3,358E-03 0,03757881 ! leukocyte migration GO:0050900 68 45 2,000 3,476E-03 0,03872377 ! phospholipid biosynthetic process GO:0008654 167 92 3,000 3,527E-03 0,03910209 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 3,666E-03 0,04046094 ! pigmentation GO:0043473 100 46 2,000 3,701E-03 0,04065714 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,9E-03 0,04265602 ! regulation of S phase GO:0033261 23 14 1,000 3,9E-03 0,04246301 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,9E-03 0,04227173 ! response to gamma radiation GO:0010332 28 14 1,000 3,9E-03 0,04208217 ! positive regulation of defense response GO:0031349 76 47 2,000 3,934E-03 0,04225119 ! response to calcium ion GO:0051592 81 47 2,000 3,934E-03 0,04206341 ! leukocyte differentiation GO:0002521 202 96 3,000 4,106E-03 0,04371771 ! positive regulation of cell cycle GO:0045787 89 48 2,000 4,175E-03 0,04425389 ! cellular component disassembly GO:0022411 86 48 2,000 4,175E-03 0,04405979 ! regulation of inflammatory response GO:0050727 75 48 2,000 4,175E-03 0,04386739 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 4,175E-03 0,04367666 ! hormone metabolic process GO:0042445 157 97 3,000 4,261E-03 0,04437972 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 4,426E-03 0,04589759 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 4,481E-03 0,04626694 ! regulation of exocytosis GO:0017157 22 15 1,000 4,481E-03 0,04606922 ! G1/S transition checkpoint GO:0031575 40 15 1,000 4,481E-03 0,04587318 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 4,481E-03 0,0456788 ! negative regulation of immune system process GO:0002683 95 50 2,000 4,685E-03 0,0475625 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 5,098E-03 0,05153692 ! intermediate filament-based process GO:0045103 32 16 1,000 5,098E-03 0,05132129 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 5,098E-03 0,05110745 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,098E-03 0,05089538 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 5,098E-03 0,05068507 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 5,098E-03 0,05047649 GO:0031114|regulation of microtubule depolymerization, ! axon cargo transport GO:0008088 43 16 1,000 5,098E-03 0,05026962 ! regulation of muscle contraction GO:0006937 81 52 2,000 5,231E-03 0,0513702 ! cartilage development GO:0051216 90 52 2,000 5,231E-03 0,05116137 ! endothelial cell migration GO:0043542 28 17 1,000 5,752E-03 0,05603172 ! regulation of viral genome replication GO:0045069 28 17 1,000 5,752E-03 0,05580579 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 5,752E-03 0,05558167 ! regulation of survival gene product expression GO:0045884 33 17 1,000 5,752E-03 0,05535934 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 5,752E-03 0,05513879 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 5,752E-03 0,05491998 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 5,752E-03 0,05470291 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 6,119E-03 0,0579602 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,443E-03 0,06078861 ! cell-substrate junction assembly GO:0007044 54 18 1,000 6,443E-03 0,06055115 ! positive regulation of cell migration GO:0030335 126 57 2,000 6,758E-03 0,06326434 ! lipid modification GO:0030258 97 57 2,000 6,758E-03 0,06301913 ! lipid phosphorylation GO:0046834 35 19 1,000 7,169E-03 0,06659586 ! forelimb morphogenesis GO:0035136 32 19 1,000 7,169E-03 0,06633972 ! pigmentation during development GO:0048066 41 19 1,000 7,169E-03 0,06608555 ! cellular response to unfolded protein GO:0034620 33 19 1,000 7,169E-03 0,06583331 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 7,169E-03 0,065583 ! neuromuscular junction development GO:0007528 34 19 1,000 7,169E-03 0,06533458 ! prostaglandin metabolic process GO:0006693 37 19 1,000 7,169E-03 0,06508803 GO:0006692|prostanoid metabolic process, ! G1 phase GO:0051318 40 19 1,000 7,169E-03 0,06484334 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 7,169E-03 0,06460048 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 7,169E-03 0,06435943 ! skeletal system morphogenesis GO:0048705 105 59 2,000 7,435E-03 0,0664978 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 7,788E-03 0,06939725 ! regulation of heart contraction GO:0008016 110 60 2,000 7,788E-03 0,06914118 ! camera-type eye development GO:0043010 116 60 2,000 7,788E-03 0,06888698 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 7,788E-03 0,06863465 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 7,788E-03 0,06838416 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 7,93E-03 0,06938296 ! protein amino acid acetylation GO:0006473 39 20 1,000 7,93E-03 0,06913157 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 7,93E-03 0,068882 ! response to alkaloid GO:0043279 38 20 1,000 7,93E-03 0,06863422 ! cellular response to starvation GO:0009267 33 20 1,000 7,93E-03 0,06838822 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 7,93E-03 0,06814398 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 7,93E-03 0,06790147 ! fatty acid beta-oxidation GO:0006635 34 20 1,000 7,93E-03 0,06766069 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 7,93E-03 0,0674216 ! detection of chemical stimulus GO:0009593 37 20 1,000 7,93E-03 0,0671842 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 7,93E-03 0,06694847 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 8,726E-03 0,07341203 ! hindlimb morphogenesis GO:0035137 43 21 1,000 8,726E-03 0,07315624 ! cell aging GO:0007569 44 21 1,000 8,726E-03 0,07290222 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 8,726E-03 0,07264997 ! DNA modification GO:0006304 34 21 1,000 8,726E-03 0,07239945 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 8,905E-03 0,07363064 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 8,905E-03 0,07337848 ! positive regulation of cell motion GO:0051272 146 64 2,000 9,298E-03 0,07634966 ! microtubule-based transport GO:0010970 54 22 1,000 9,557E-03 0,0782099 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 9,557E-03 0,07794478 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 9,557E-03 0,07768146 ! positive regulation of B cell activation GO:0050871 38 22 1,000 9,557E-03 0,0774199 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 9,557E-03 0,0771601 ! protein stabilization GO:0050821 39 22 1,000 9,557E-03 0,07690204 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 0,01042092 0,0835758 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 0,01042092 0,08329814 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 0,01042092 0,08302232 ! regulation of viral reproduction GO:0050792 38 23 1,000 0,01042092 0,08274831 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 0,01042092 0,08247612 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 0,01042092 0,0822057 ! negative regulation of catabolic process GO:0009895 50 23 1,000 0,01042092 0,08193706 ! homeostasis of number of cells GO:0048872 114 67 2,000 0,0105347 0,08256189 ! activation of immune response GO:0002253 105 67 2,000 0,0105347 0,08229383 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 0,01096715 0,08539471 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01131827 0,08784436 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01131827 0,0875619 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 0,01131827 0,08728126 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 0,01131827 0,0870024 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 0,01131827 0,08672532 ! protein tetramerization GO:0051262 52 24 1,000 0,01131827 0,08645001 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01224837 0,09325819 ! myelination GO:0042552 45 25 1,000 0,01224837 0,092964 ! vasculogenesis GO:0001570 46 25 1,000 0,01224837 0,09267166 ! receptor metabolic process GO:0043112 46 25 1,000 0,01224837 0,09238115 ! chromosome condensation GO:0030261 45 25 1,000 0,01224837 0,09209246 ! response to starvation GO:0042594 42 25 1,000 0,01224837 0,09180557 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01224837 0,09152046 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 0,01224837 0,09123711 ! immunoglobulin production GO:0002377 55 25 1,000 0,01224837 0,09095551 GO:0002440|production of molecular mediator of immune response, ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01224837 0,09067565 ! neural tube closure GO:0001843 49 25 1,000 0,01224837 0,09039751 GO:0060606|tube closure, ! B cell activation GO:0042113 160 71 2,000 0,01232548 0,09068837 ! tube lumen formation GO:0035148 50 26 1,000 0,01321076 0,09690578 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01321076 0,09661123 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01321076 0,09631847 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 0,01321076 0,09602748 ! somatic diversification of immune receptors GO:0002200 56 26 1,000 0,01321076 0,09573824 ! learning or memory GO:0007611 147 73 2,000 0,01328221 0,09596695 ! axon guidance GO:0007411 139 73 2,000 0,01328221 0,09567963 ! neurotransmitter transport GO:0006836 123 74 2,000 0,01377603 0,09894065 ! eye development GO:0001654 143 74 2,000 0,01377603 0,09864619 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01420496 0,10141584 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01420496 0,10111579 ! male gonad development GO:0008584 44 27 1,000 0,01420496 0,10081751 ! primary neural tube formation GO:0014020 51 27 1,000 0,01420496 0,10052099 ! fat cell differentiation GO:0045444 50 27 1,000 0,01420496 0,10022621 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01420496 0,09993315 ! glutathione metabolic process GO:0006749 39 27 1,000 0,01420496 0,0996418 ! dendrite development GO:0016358 59 28 1,000 0,0152305 0,10652496 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,0152305 0,10621619 ! lipid oxidation GO:0034440 43 28 1,000 0,0152305 0,10590921 GO:0019395|fatty acid oxidation, ! protein oligomerization GO:0051259 139 78 2,000 0,01585493 0,10993358 ! regulation of pH GO:0006885 43 29 1,000 0,01628692 0,1126044 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01628692 0,11228175 ! response to metal ion GO:0010038 140 80 2,000 0,01695687 0,11656634 ! cell junction assembly GO:0034329 78 30 1,000 0,01737376 0,11909192 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01737376 0,11875359 GO:0008366|axon ensheathment, ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01737376 0,11841718 ! response to heat GO:0009408 50 30 1,000 0,01737376 0,11808267 ! response to drug GO:0042493 143 82 2,000 0,01810066 0,12267656 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01849056 0,12496713 ! fatty acid catabolic process GO:0009062 48 31 1,000 0,01849056 0,12461708 ! metanephros development GO:0001656 74 32 1,000 0,01963689 0,13197304 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01963689 0,13160543 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01963689 0,13123986 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01963689 0,13087631 ! response to unfolded protein GO:0006986 131 85 2,000 0,01989503 0,13223052 ! response to inorganic substance GO:0010035 153 86 2,000 0,02051418 0,13597 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,02081228 0,13756689 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,02081228 0,13718999 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,02081228 0,13681516 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,02201631 0,14433579 ! mismatch repair GO:0006298 46 34 1,000 0,02201631 0,14394358 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,02243475 0,14628184 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,02309599 0,15018633 ! regulation of muscle development GO:0048634 70 35 1,000 0,02324853 0,1507708 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,02324853 0,1503655 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,02324853 0,14996238 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02324853 0,14956141 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,02324853 0,14916258 ! neural tube formation GO:0001841 67 35 1,000 0,02324853 0,14876587 ! response to protein stimulus GO:0051789 149 91 2,000 0,02376775 0,15168489 ! regulation of defense response GO:0031347 149 92 2,000 0,02445003 0,15562639 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,02450852 0,15558708 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 86 36 1,000 0,02450852 0,15517764 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02450852 0,15477035 ! meiosis I GO:0007127 65 37 1,000 0,02579585 0,16247335 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,02579585 0,16204914 ! transcription initiation GO:0006352 153 94 2,000 0,02584614 0,16194223 ! regulation of T cell activation GO:0050863 158 94 2,000 0,02584614 0,1615216 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,0271101 0,16898161 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,0271101 0,16854496 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,0271101 0,16811057 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of immune response GO:0050778 156 96 2,000 0,02728426 0,1687556 ! detection of stimulus GO:0051606 151 96 2,000 0,02728426 0,16832289 ! protein ubiquitination GO:0016567 217 97 2,000 0,02801905 0,17241388 ! mammary gland development GO:0030879 86 39 1,000 0,02845085 0,17462434 ! learning GO:0007612 77 39 1,000 0,02845085 0,17418001 ! ear morphogenesis GO:0042471 60 39 1,000 0,02845085 0,17373793 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02845085 0,17329808 ! segmentation GO:0035282 67 39 1,000 0,02845085 0,17286046 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02845085 0,17242504 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02952002 0,17845522 GO:0060538|skeletal muscle organ development, ! feeding behavior GO:0007631 59 40 1,000 0,02981769 0,17980288 ! maintenance of protein location GO:0045185 91 40 1,000 0,02981769 0,17935338 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03262799 0,19576793 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,03262799 0,19528095 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,03262799 0,19479638 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,03262799 0,19431421 ! neuron migration GO:0001764 79 42 1,000 0,03262799 0,19383442 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,03262799 0,193357 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0332528 0,19657552 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0332528 0,19609371 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0332528 0,19561427 ! neuron fate determination GO:0048664 7 5 0,000 0,0332528 0,19513716 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0332528 0,19466237 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0332528 0,19418989 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0332528 0,1937197 ! polyol transport GO:0015791 12 5 0,000 0,0332528 0,19325178 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0332528 0,19278611 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0332528 0,19232268 ! response to superoxide GO:0000303 10 5 0,000 0,0332528 0,19186148 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0332528 0,19140248 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0332528 0,19094567 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0332528 0,19049104 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0332528 0,19003856 ! female meiosis GO:0007143 7 5 0,000 0,0332528 0,18958824 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0332528 0,18914004 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0332528 0,18869395 ! cobalt ion transport GO:0006824 11 5 0,000 0,0332528 0,18824997 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0332528 0,18780806 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0332528 0,18736823 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0332528 0,18693046 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0332528 0,18649472 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0332528 0,18606101 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0332528 0,18562932 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0332528 0,18519962 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0332528 0,18477191 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0332528 0,18434616 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0332528 0,18392238 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0332528 0,18350054 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0332528 0,18308063 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0332528 0,18266264 ! negative chemotaxis GO:0050919 14 5 0,000 0,0332528 0,18224655 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0332528 0,18183235 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0332528 0,18142003 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0332528 0,18100958 ! behavioral response to pain GO:0048266 9 5 0,000 0,0332528 0,18060098 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0332528 0,18019422 ! Notch receptor processing GO:0007220 8 5 0,000 0,0332528 0,17978929 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0332528 0,17938618 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0332528 0,17898487 ! micturition GO:0060073 9 5 0,000 0,0332528 0,17858535 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0332528 0,17818761 ! copulation GO:0007620 9 5 0,000 0,0332528 0,17779163 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0332528 0,17739742 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0332528 0,17700495 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0332528 0,17661421 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0332528 0,17622519 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0332528 0,17583788 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0332528 0,17545227 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0332528 0,17506835 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0332528 0,1746861 ! grooming behavior GO:0007625 6 5 0,000 0,0332528 0,17430552 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0332528 0,1739266 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0332528 0,17354932 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0332528 0,17317367 ! response to protozoan GO:0001562 10 5 0,000 0,0332528 0,17279964 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,0332528 0,17242723 ! lymph vessel development GO:0001945 10 5 0,000 0,0332528 0,17205642 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0332528 0,1716872 ! endochondral ossification GO:0001958 16 5 0,000 0,0332528 0,17131956 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0332528 0,17095349 ! parathyroid gland development GO:0060017 13 5 0,000 0,0332528 0,17058899 ! anagen GO:0042640 6 5 0,000 0,0332528 0,17022603 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0332528 0,16986462 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0332528 0,16950474 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0332528 0,16914637 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0332528 0,16878953 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0332528 0,16843418 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0332528 0,16808033 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0332528 0,16772796 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0332528 0,16737706 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0332528 0,16702763 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0332528 0,16667966 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0332528 0,16633313 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0332528 0,16598804 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0332528 0,16564438 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0332528 0,16530214 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0332528 0,16496131 ! histidine catabolic process GO:0006548 6 5 0,000 0,0332528 0,16462188 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0332528 0,16428385 ! valine metabolic process GO:0006573 10 5 0,000 0,0332528 0,1639472 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0332528 0,16361193 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0332528 0,16327803 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0332528 0,16294549 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0332528 0,1626143 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0332528 0,16228445 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0332528 0,16195594 ! polyol catabolic process GO:0046174 7 5 0,000 0,0332528 0,16162876 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0332528 0,16130289 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0332528 0,16097834 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0332528 0,16065509 ! muscle cell migration GO:0014812 8 5 0,000 0,0332528 0,16033314 ! mitochondrial fission GO:0000266 8 5 0,000 0,0332528 0,16001247 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0332528 0,15969308 ! mRNA transcription GO:0009299 9 5 0,000 0,0332528 0,15937497 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0332528 0,15905812 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0332528 0,15874253 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0332528 0,15842819 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0332528 0,15811509 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0332528 0,15780323 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0332528 0,15749259 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0332528 0,15718317 ! response to food GO:0032094 6 5 0,000 0,0332528 0,15687497 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0332528 0,15656798 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0332528 0,15626218 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0332528 0,15595757 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0332528 0,15565415 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0332528 0,15535191 ! forebrain neuron development GO:0021884 13 5 0,000 0,0332528 0,15505084 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0332528 0,15475094 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0332528 0,15445219 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0332528 0,1541546 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0332528 0,15385814 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0332528 0,15356283 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0332528 0,15326865 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0332528 0,15297559 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0332528 0,15268366 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0332528 0,15239283 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0332528 0,15210311 ! basic amino acid transport GO:0015802 11 5 0,000 0,0332528 0,15181449 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0332528 0,15152696 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0332528 0,15124052 ! depyrimidination GO:0045008 10 5 0,000 0,0332528 0,15095516 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0332528 0,15067088 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0332528 0,15038766 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0332528 0,15010551 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0332528 0,14982441 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,0332528 0,14954437 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0332528 0,14926536 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0332528 0,1489874 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0332528 0,14871047 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0332528 0,14843457 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0332528 0,1481597 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0332528 0,14788583 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0332528 0,14761298 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0332528 0,14734113 ! response to arsenic GO:0046685 10 5 0,000 0,0332528 0,14707029 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0332528 0,14680043 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0332528 0,14653157 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0332528 0,14626368 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0332528 0,14599678 ! response to cadmium ion GO:0046686 7 5 0,000 0,0332528 0,14573085 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0332528 0,14546588 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0332528 0,14520188 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0332528 0,14493883 ! decidualization GO:0046697 11 5 0,000 0,0332528 0,14467674 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0332528 0,14441559 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0332528 0,14415538 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0332528 0,14389611 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0332528 0,14363777 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0332528 0,14338035 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0332528 0,14312386 ! neural tube patterning GO:0021532 7 5 0,000 0,0332528 0,14286828 ! embryonic cleavage GO:0040016 6 5 0,000 0,0332528 0,14261361 ! peroxisome fission GO:0016559 5 5 0,000 0,0332528 0,14235985 ! histone demethylation GO:0016577 10 5 0,000 0,0332528 0,14210699 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0332528 0,14185503 ! mitotic recombination GO:0006312 9 5 0,000 0,0332528 0,14160396 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0332528 0,14135377 ! metaphase plate congression GO:0051310 7 5 0,000 0,0332528 0,14110447 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0332528 0,14085605 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0332528 0,1406085 ! enteric nervous system development GO:0048484 8 5 0,000 0,0332528 0,14036182 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0332528 0,140116 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0332528 0,13987104 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0332528 0,13962694 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0332528 0,13938369 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0332528 0,13914128 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0332528 0,13889971 ! plasminogen activation GO:0031639 5 5 0,000 0,0332528 0,13865899 ! B cell homeostasis GO:0001782 13 5 0,000 0,0332528 0,13841909 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0332528 0,13818003 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0332528 0,13794179 ! metaphase GO:0051323 8 5 0,000 0,0332528 0,13770436 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0332528 0,13746776 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0332528 0,13723196 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0332528 0,13699698 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0332528 0,1367628 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0332528 0,13652941 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0332528 0,13629682 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0332528 0,13606503 ! response to redox state GO:0051775 5 5 0,000 0,0332528 0,13583402 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0332528 0,13560379 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0332528 0,13537434 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0332528 0,13514567 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0332528 0,13491777 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0332528 0,13469063 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0332528 0,13446426 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0332528 0,13423865 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0332528 0,13401379 ! striatum development GO:0021756 9 5 0,000 0,0332528 0,13378969 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0332528 0,13356634 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0332528 0,13334373 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0332528 0,13312186 ! glial cell migration GO:0008347 11 5 0,000 0,0332528 0,13290072 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0332528 0,13268032 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0332528 0,13246065 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0332528 0,13224171 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0332528 0,13202349 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0332528 0,13180599 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0332528 0,1315892 ! neuroprotection GO:0043526 6 5 0,000 0,0332528 0,13137313 ! neural plate development GO:0001840 8 5 0,000 0,0332528 0,13115776 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0332528 0,1309431 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0332528 0,13072914 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0332528 0,13051588 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0332528 0,13030331 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0332528 0,13009144 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0332528 0,12988025 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0332528 0,12966975 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0332528 0,12945993 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0332528 0,12925078 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0332528 0,12904232 ! spindle assembly GO:0051225 6 5 0,000 0,0332528 0,12883452 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0332528 0,12862739 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0332528 0,12842092 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0332528 0,12821512 ! drug metabolic process GO:0017144 6 5 0,000 0,0332528 0,12800998 ! phospholipid scrambling GO:0017121 8 5 0,000 0,0332528 0,12780549 ! organ regeneration GO:0031100 7 5 0,000 0,0332528 0,12760165 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0332528 0,12739846 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0332528 0,12719592 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0332528 0,12699402 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,03407065 0,12991123 ! glucose transport GO:0015758 65 43 1,000 0,03407065 0,12970567 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,03407065 0,12950077 ! neural tube development GO:0021915 77 43 1,000 0,03407065 0,12929651 ! male sex differentiation GO:0046661 76 44 1,000 0,03553779 0,13465185 ! biopolymer methylation GO:0043414 84 44 1,000 0,03553779 0,13444013 ! B cell differentiation GO:0030183 107 44 1,000 0,03553779 0,13422908 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03553779 0,13401869 ! hexose transport GO:0008645 67 44 1,000 0,03553779 0,13380896 GO:0015749|monosaccharide transport, ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03702902 0,13920596 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,03702902 0,13898879 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,03854394 0,14444971 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,03854394 0,14422506 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,03854394 0,14400111 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03977012 0,14835181 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03977012 0,14812217 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03977012 0,14789323 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03977012 0,147665 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03977012 0,14743747 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03977012 0,14721064 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03977012 0,14698451 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03977012 0,14675908 ! sleep GO:0030431 13 6 0,000 0,03977012 0,14653433 ! response to oxygen radical GO:0000305 11 6 0,000 0,03977012 0,14631027 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03977012 0,1460869 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03977012 0,14586421 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03977012 0,14564219 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03977012 0,14542085 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03977012 0,14520018 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03977012 0,14498018 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03977012 0,14476085 ! forebrain regionalization GO:0021871 8 6 0,000 0,03977012 0,14454217 ! male meiosis GO:0007140 7 6 0,000 0,03977012 0,14432416 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03977012 0,14410681 ! response to zinc ion GO:0010043 9 6 0,000 0,03977012 0,1438901 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03977012 0,14367405 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03977012 0,14345865 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03977012 0,14324389 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03977012 0,14302977 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03977012 0,1428163 ! malate metabolic process GO:0006108 11 6 0,000 0,03977012 0,14260346 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03977012 0,14239125 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03977012 0,14217967 ! protein refolding GO:0042026 15 6 0,000 0,03977012 0,14196872 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03977012 0,1417584 ! opsonization GO:0008228 8 6 0,000 0,03977012 0,1415487 ! mating behavior GO:0007617 7 6 0,000 0,03977012 0,14133961 ! neuron remodeling GO:0016322 15 6 0,000 0,03977012 0,14113115 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03977012 0,1409233 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03977012 0,14071606 ! equilibrioception GO:0050957 14 6 0,000 0,03977012 0,14050943 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03977012 0,1403034 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03977012 0,14009798 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03977012 0,13989316 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03977012 0,13968893 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03977012 0,1394853 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03977012 0,13928227 ! toxin metabolic process GO:0009404 11 6 0,000 0,03977012 0,13907982 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03977012 0,13887797 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03977012 0,13867669 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03977012 0,138476 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03977012 0,13827589 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03977012 0,13807636 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03977012 0,1378774 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03977012 0,13767902 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03977012 0,1374812 ! thymic T cell selection GO:0045061 12 6 0,000 0,03977012 0,13728396 ! protein lipoylation GO:0009249 10 6 0,000 0,03977012 0,13708728 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03977012 0,13689116 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03977012 0,1366956 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03977012 0,1365006 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03977012 0,13630615 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03977012 0,13611226 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03977012 0,13591892 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03977012 0,13572613 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03977012 0,13553388 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03977012 0,13534218 ! hyperosmotic response GO:0006972 9 6 0,000 0,03977012 0,13515101 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03977012 0,13496039 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03977012 0,13477031 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03977012 0,13458076 ! urea metabolic process GO:0019627 7 6 0,000 0,03977012 0,13439174 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03977012 0,13420325 ! neutrophil activation GO:0042119 8 6 0,000 0,03977012 0,13401529 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03977012 0,13382786 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03977012 0,13364095 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03977012 0,13345456 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03977012 0,13326869 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03977012 0,13308334 ! neuron apoptosis GO:0051402 9 6 0,000 0,03977012 0,1328985 ! nucleoside salvage GO:0043174 9 6 0,000 0,03977012 0,13271417 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03977012 0,13253036 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03977012 0,13234705 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03977012 0,13216425 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03977012 0,13198196 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03977012 0,13180016 ! carnitine transport GO:0015879 10 6 0,000 0,03977012 0,13161887 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03977012 0,13143808 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03977012 0,13125778 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03977012 0,13107797 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03977012 0,13089866 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03977012 0,13071983 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03977012 0,1305415 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03977012 0,13036365 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03977012 0,13018628 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03977012 0,1300094 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03977012 0,129833 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03977012 0,12965707 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03977012 0,12948162 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03977012 0,12930665 ! neural nucleus development GO:0048857 14 6 0,000 0,03977012 0,12913214 ! response to UV-C GO:0010225 11 6 0,000 0,03977012 0,12895811 ! astrocyte development GO:0014002 15 6 0,000 0,03977012 0,12878455 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03977012 0,12861145 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03977012 0,12843882 ! interaction with symbiont GO:0051702 13 6 0,000 0,03977012 0,12826665 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03977012 0,12809494 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03977012 0,12792369 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03977012 0,1277529 ! response to copper ion GO:0046688 10 6 0,000 0,03977012 0,12758256 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03977012 0,12741267 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03977012 0,12724324 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03977012 0,12707426 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03977012 0,12690573 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03977012 0,12673764 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03977012 0,12657 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03977012 0,1264028 ! hair follicle maturation GO:0048820 7 6 0,000 0,03977012 0,12623604 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03977012 0,12606972 ! Schwann cell development GO:0014044 15 6 0,000 0,03977012 0,12590384 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03977012 0,1257384 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03977012 0,12557338 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03977012 0,12540881 ! subpallium development GO:0021544 10 6 0,000 0,03977012 0,12524466 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03977012 0,12508094 ! histone ubiquitination GO:0016574 8 6 0,000 0,03977012 0,12491765 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03977012 0,12475478 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03977012 0,12459234 ! G2 phase GO:0051319 16 6 0,000 0,03977012 0,12443032 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03977012 0,12426873 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03977012 0,12410755 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03977012 0,12394679 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03977012 0,12378644 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03977012 0,12362651 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03977012 0,12346699 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03977012 0,12330788 ! receptor internalization GO:0031623 10 6 0,000 0,03977012 0,12314919 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03977012 0,1229909 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03977012 0,12283301 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03977012 0,12267554 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03977012 0,12251846 ! protein deubiquitination GO:0016579 14 6 0,000 0,03977012 0,12236179 ! protein destabilization GO:0031648 9 6 0,000 0,03977012 0,12220552 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03977012 0,12204964 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03977012 0,12189416 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03977012 0,12173908 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03977012 0,12158439 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03977012 0,1214301 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03977012 0,1212762 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03977012 0,12112268 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03977012 0,12096956 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03977012 0,12081682 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03977012 0,12066446 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03977012 0,12051249 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03977012 0,1203609 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03977012 0,1202097 ! catecholamine transport GO:0051937 9 6 0,000 0,03977012 0,12005887 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03977012 0,11990842 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03977012 0,11975835 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03977012 0,11960865 ! maternal placenta development GO:0001893 12 6 0,000 0,03977012 0,11945932 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03977012 0,11931037 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03977012 0,11916179 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03977012 0,11901358 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03977012 0,11886574 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03977012 0,11871826 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03977012 0,11857115 ! endosome transport GO:0016197 108 47 1,000 0,04008218 0,11935361 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,04008218 0,11920607 ! methylation GO:0032259 90 47 1,000 0,04008218 0,11905891 ! protein homooligomerization GO:0051260 76 47 1,000 0,04008218 0,1189121 ! mitochondrial transport GO:0006839 82 48 1,000 0,04164335 0,12339149 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,04164335 0,12323972 ! regulation of action potential GO:0001508 95 49 1,000 0,04322708 0,12776947 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,04322708 0,12761269 ! peptide metabolic process GO:0006518 76 49 1,000 0,04322708 0,1274563 ! response to temperature stimulus GO:0009266 76 49 1,000 0,04322708 0,1273003 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,04322708 0,12714468 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,04322708 0,12698943 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,04322708 0,12683457 ! histone modification GO:0016570 91 50 1,000 0,04483299 0,13138633 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,04483299 0,1312265 ! tRNA transcription GO:0009304 14 7 0,000 0,04624373 0,13519126 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04624373 0,13502719 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04624373 0,13486352 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04624373 0,13470025 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04624373 0,13453737 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04624373 0,13437489 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04624373 0,1342128 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04624373 0,13405109 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04624373 0,13388978 ! prostate gland development GO:0030850 13 7 0,000 0,04624373 0,13372886 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04624373 0,13356832 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04624373 0,13340816 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04624373 0,13324839 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04624373 0,133089 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04624373 0,13293 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04624373 0,13277137 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04624373 0,13261312 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04624373 0,13245525 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04624373 0,13229775 ! glycolipid transport GO:0046836 10 7 0,000 0,04624373 0,13214063 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04624373 0,13198388 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04624373 0,1318275 ! neuron adhesion GO:0007158 12 7 0,000 0,04624373 0,13167149 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04624373 0,13151585 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04624373 0,13136058 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04624373 0,13120567 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04624373 0,13105113 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04624373 0,13089695 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04624373 0,13074313 ! mRNA stabilization GO:0048255 18 7 0,000 0,04624373 0,13058968 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04624373 0,13043659 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04624373 0,13028385 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04624373 0,13013147 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04624373 0,12997945 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04624373 0,12982778 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04624373 0,12967647 ! lipoprotein transport GO:0042953 14 7 0,000 0,04624373 0,1295255 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04624373 0,12937489 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04624373 0,12922463 ! rhythmic behavior GO:0007622 15 7 0,000 0,04624373 0,12907472 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04624373 0,12892515 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04624373 0,12877593 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04624373 0,12862706 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04624373 0,12847853 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04624373 0,12833034 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04624373 0,1281825 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04624373 0,12803499 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04624373 0,12788783 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04624373 0,127741 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04624373 0,1275945 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04624373 0,12744835 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04624373 0,12730253 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04624373 0,12715704 ! spinal cord patterning GO:0021511 13 7 0,000 0,04624373 0,12701188 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04624373 0,12686706 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04624373 0,12672256 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04624373 0,12657839 ! adrenal gland development GO:0030325 17 7 0,000 0,04624373 0,12643455 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04624373 0,12629104 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04624373 0,12614785 ! ovulation GO:0030728 9 7 0,000 0,04624373 0,12600499 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04624373 0,12586245 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04624373 0,12572023 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04624373 0,12557834 ! microtubule nucleation GO:0007020 20 7 0,000 0,04624373 0,12543676 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04624373 0,1252955 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04624373 0,12515456 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04624373 0,12501394 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04624373 0,12487363 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04624373 0,12473364 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04624373 0,12459396 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04624373 0,12445459 ! galactose metabolic process GO:0006012 13 7 0,000 0,04624373 0,12431554 ! vesicle fusion GO:0006906 17 7 0,000 0,04624373 0,12417679 ! response to dietary excess GO:0002021 8 7 0,000 0,04624373 0,12403836 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04624373 0,12390023 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04624373 0,12376241 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04624373 0,1236249 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04624373 0,12348769 ! organ growth GO:0035265 15 7 0,000 0,04624373 0,12335078 ! purine salvage GO:0043101 10 7 0,000 0,04624373 0,12321418 ! nucleoside transport GO:0015858 8 7 0,000 0,04624373 0,12307788 ! parturition GO:0007567 14 7 0,000 0,04624373 0,12294189 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04624373 0,12280619 ! rRNA modification GO:0000154 14 7 0,000 0,04624373 0,12267079 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04624373 0,12253569 ! spindle checkpoint GO:0031577 15 7 0,000 0,04624373 0,12240089 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04624373 0,12226638 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04624373 0,12213217 ! macrophage differentiation GO:0030225 11 7 0,000 0,04624373 0,12199825 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04624373 0,12186463 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04624373 0,1217313 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04624373 0,12159826 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04624373 0,12146551 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04624373 0,12133305 ! fibrinolysis GO:0042730 10 7 0,000 0,04624373 0,12120088 ! eating behavior GO:0042755 7 7 0,000 0,04624373 0,121069 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04624373 0,1209374 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04624373 0,12080609 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04624373 0,12067506 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04624373 0,12054432 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04624373 0,12041386 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04624373 0,12028368 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04624373 0,12015379 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04624373 0,12002417 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04624373 0,11989484 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04624373 0,11976578 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04624373 0,119637 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04624373 0,11950849 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04624373 0,11938027 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04624373 0,11925231 ! regulation of meiosis GO:0040020 12 7 0,000 0,04624373 0,11912463 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04624373 0,11899723 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04624373 0,11887009 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04624373 0,11874323 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04624373 0,11861664 ! transcription termination GO:0006353 13 7 0,000 0,04624373 0,11849032 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04624373 0,11836426 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04624373 0,11823848 ! anaphase GO:0051322 17 7 0,000 0,04624373 0,11811296 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 18 7 0,000 0,04624373 0,11798771 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04624373 0,11786272 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04624373 0,117738 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04624373 0,11761354 ! diuresis GO:0030146 12 7 0,000 0,04624373 0,11748934 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04624373 0,11736541 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04624373 0,11724174 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04624373 0,11711832 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04624373 0,11699517 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04624373 0,11687228 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04624373 0,11674964 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04624373 0,11662726 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04624373 0,11650514 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04624373 0,11638327 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04624373 0,11626166 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04624373 0,1161403 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04624373 0,11601919 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04624373 0,11589834 ! lymph node development GO:0048535 10 7 0,000 0,04624373 0,11577774 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04624373 0,11565739 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04624373 0,11553729 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04624373 0,11541744 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04624373 0,11529783 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04624373 0,11517848 ! adult feeding behavior GO:0008343 9 7 0,000 0,04624373 0,11505937 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04624373 0,1149405 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04624373 0,11482189 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04624373 0,11470351 ! muscle adaptation GO:0043500 14 7 0,000 0,04624373 0,11458538 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04624373 0,1144675 ! retina homeostasis GO:0001895 12 7 0,000 0,04624373 0,11434985 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04624373 0,11423245 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04624373 0,11411529 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04624373 0,11399837 ! protein prenylation GO:0018342 18 7 0,000 0,04624373 0,11388169 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04624373 0,11376524 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04624373 0,11364904 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04624373 0,11353307 ! positive regulation of binding GO:0051099 78 51 1,000 0,04646073 0,11394955 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,04646073 0,11383351 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,04646073 0,11371771 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,04810992 0,11763462 ! covalent chromatin modification GO:0016569 101 52 1,000 0,04810992 0,11751519 ! synapse organization GO:0050808 85 52 1,000 0,04810992 0,11739601 ! regulation of translational initiation GO:0006446 82 53 1,000 0,0497802 0,1213487 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,0497802 0,12122588 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,05147123 0,12521717 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,05147123 0,12509068 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,05147123 0,12496446 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0526739 0,12775545 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0526739 0,12762679 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0526739 0,1274984 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0526739 0,12737026 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0526739 0,12724237 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0526739 0,12711475 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0526739 0,12698738 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0526739 0,12686027 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0526739 0,12673341 ! meiotic prophase I GO:0007128 13 8 0,000 0,0526739 0,1266068 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0526739 0,12648044 ! oligopeptide transport GO:0006857 15 8 0,000 0,0526739 0,12635434 ! UTP metabolic process GO:0046051 8 8 0,000 0,0526739 0,12622849 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0526739 0,12610289 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0526739 0,12597754 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0526739 0,12585244 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0526739 0,12572758 ! succinate metabolic process GO:0006105 14 8 0,000 0,0526739 0,12560298 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0526739 0,12547862 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0526739 0,12535451 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0526739 0,12523064 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0526739 0,12510701 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0526739 0,12498363 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0526739 0,1248605 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0526739 0,1247376 ! reflex GO:0060004 16 8 0,000 0,0526739 0,12461495 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0526739 0,12449254 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0526739 0,12437037 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0526739 0,12424844 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0526739 0,12412674 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0526739 0,12400529 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0526739 0,12388407 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0526739 0,12376309 ! pigment granule organization GO:0048753 16 8 0,000 0,0526739 0,12364235 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0526739 0,12352184 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0526739 0,12340156 ! histidine metabolic process GO:0006547 16 8 0,000 0,0526739 0,12328152 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0526739 0,12316172 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0526739 0,12304214 ! glycine catabolic process GO:0006546 13 8 0,000 0,0526739 0,1229228 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0526739 0,12280369 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0526739 0,12268481 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0526739 0,12256616 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0526739 0,12244773 ! melanin metabolic process GO:0006582 15 8 0,000 0,0526739 0,12232954 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0526739 0,12221158 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0526739 0,12209384 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0526739 0,12197633 ! macrophage activation GO:0042116 12 8 0,000 0,0526739 0,12185904 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0526739 0,12174198 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0526739 0,12162515 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0526739 0,12150854 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0526739 0,12139215 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0526739 0,12127599 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0526739 0,12116004 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0526739 0,12104432 ! osteoblast development GO:0002076 16 8 0,000 0,0526739 0,12092882 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0526739 0,12081354 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0526739 0,12069848 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0526739 0,12058364 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0526739 0,12046902 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0526739 0,12035461 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0526739 0,12024042 ! response to UV-B GO:0010224 16 8 0,000 0,0526739 0,12012645 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0526739 0,12001269 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0526739 0,11989915 ! intermediate filament organization GO:0045109 12 8 0,000 0,0526739 0,11978583 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0526739 0,11967272 ! cellular extravasation GO:0045123 12 8 0,000 0,0526739 0,11955982 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0526739 0,11944713 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0526739 0,11933466 ! response to antibiotic GO:0046677 11 8 0,000 0,0526739 0,11922239 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0526739 0,11911034 ! response to tropane GO:0014073 15 8 0,000 0,0526739 0,1189985 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0526739 0,11888687 ! melanosome transport GO:0032402 13 8 0,000 0,0526739 0,11877545 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0526739 0,11866424 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0526739 0,11855323 ! mast cell activation GO:0045576 14 8 0,000 0,0526739 0,11844243 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0526739 0,11833184 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0526739 0,11822146 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0526739 0,11811128 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0526739 0,11800131 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0526739 0,11789154 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0526739 0,11778198 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0526739 0,11767261 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0526739 0,11756346 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0526739 0,1174545 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0526739 0,11734575 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0526739 0,11723719 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0526739 0,11712884 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0526739 0,11702069 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0526739 0,11691274 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0526739 0,11680498 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0526739 0,11669743 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0526739 0,11659007 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0526739 0,11648291 ! hormone catabolic process GO:0042447 17 8 0,000 0,0526739 0,11637595 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0526739 0,11626918 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0526739 0,11616261 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0526739 0,11605623 ! ATP catabolic process GO:0006200 11 8 0,000 0,0526739 0,11595005 ! blastocyst growth GO:0001832 19 8 0,000 0,0526739 0,11584406 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0526739 0,11573827 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0526739 0,11563267 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0526739 0,11552726 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0526739 0,11542204 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0526739 0,11531702 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0526739 0,11521219 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0526739 0,11510754 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0526739 0,11500309 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0526739 0,11489883 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0526739 0,11479475 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0526739 0,11469086 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0526739 0,11458717 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0526739 0,11448365 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0526739 0,11438033 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0526739 0,11427719 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,05318264 0,11527697 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,05318264 0,11517321 ! nuclear export GO:0051168 97 55 1,000 0,05318264 0,11506963 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,05491409 0,11870916 ! muscle fiber development GO:0048747 112 57 1,000 0,05666523 0,12238469 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,05666523 0,12227493 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,05666523 0,12216537 ! maintenance of location GO:0051235 118 57 1,000 0,05666523 0,122056 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,05843573 0,12575703 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05906093 0,12698893 ! axon extension GO:0048675 15 9 0,000 0,05906093 0,12687554 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05906093 0,12676236 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05906093 0,12664938 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05906093 0,12653661 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05906093 0,12642403 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05906093 0,12631165 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05906093 0,12619947 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05906093 0,1260875 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05906093 0,12597572 ! phosphate transport GO:0006817 19 9 0,000 0,05906093 0,12586413 ! reproductive behavior GO:0019098 19 9 0,000 0,05906093 0,12575275 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05906093 0,12564156 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05906093 0,12553057 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05906093 0,12541978 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05906093 0,12530918 ! GTP metabolic process GO:0046039 9 9 0,000 0,05906093 0,12519877 ! RNA methylation GO:0001510 15 9 0,000 0,05906093 0,12508856 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05906093 0,12497855 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05906093 0,12486872 ! artery development GO:0060840 24 9 0,000 0,05906093 0,12475909 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05906093 0,12464966 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05906093 0,12454041 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05906093 0,12443136 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05906093 0,12432249 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05906093 0,12421382 ! chemosensory behavior GO:0007635 20 9 0,000 0,05906093 0,12410533 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05906093 0,12399704 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05906093 0,12388893 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05906093 0,12378102 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05906093 0,12367329 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05906093 0,12356575 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05906093 0,12345839 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05906093 0,12335122 ! protein targeting to ER GO:0045047 22 9 0,000 0,05906093 0,12324424 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05906093 0,12313744 ! T cell selection GO:0045058 23 9 0,000 0,05906093 0,12303083 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05906093 0,1229244 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05906093 0,12281816 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05906093 0,1227121 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05906093 0,12260622 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05906093 0,12250052 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05906093 0,12239501 ! mannose metabolic process GO:0006013 13 9 0,000 0,05906093 0,12228968 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05906093 0,12218453 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05906093 0,12207956 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05906093 0,12197477 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05906093 0,12187016 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05906093 0,12176573 ! ruffle organization GO:0031529 15 9 0,000 0,05906093 0,12166148 ! retinol metabolic process GO:0042572 18 9 0,000 0,05906093 0,12155741 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05906093 0,12145351 ! behavioral fear response GO:0001662 22 9 0,000 0,05906093 0,12134979 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05906093 0,12124625 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05906093 0,12114289 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05906093 0,1210397 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05906093 0,12093669 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05906093 0,12083385 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05906093 0,12073119 ! segment specification GO:0007379 13 9 0,000 0,05906093 0,1206287 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05906093 0,12052639 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05906093 0,12042424 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05906093 0,12032228 ! response to amine stimulus GO:0014075 13 9 0,000 0,05906093 0,12022048 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05906093 0,12011886 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05906093 0,12001741 ! erythrocyte development GO:0048821 15 9 0,000 0,05906093 0,11991613 ! gas homeostasis GO:0033483 16 9 0,000 0,05906093 0,11981502 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05906093 0,11971408 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05906093 0,11961331 ! renal water homeostasis GO:0003091 14 9 0,000 0,05906093 0,11951271 ! postreplication repair GO:0006301 22 9 0,000 0,05906093 0,11941228 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05906093 0,11931201 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05906093 0,11921192 ! icosanoid secretion GO:0032309 15 9 0,000 0,05906093 0,11911199 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05906093 0,11901223 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05906093 0,11891264 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05906093 0,11881322 ! regulation of cell division GO:0051302 15 9 0,000 0,05906093 0,11871396 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05906093 0,11861487 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05906093 0,11851594 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05906093 0,11841717 ! sterol catabolic process GO:0016127 11 9 0,000 0,05906093 0,11831857 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05906093 0,11822014 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05906093 0,11812187 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05906093 0,11802376 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05906093 0,11792582 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05906093 0,11782803 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05906093 0,11773041 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05906093 0,11763295 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05906093 0,11753566 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05906093 0,11743852 ! purine base metabolic process GO:0006144 21 9 0,000 0,05906093 0,11734154 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05906093 0,11724473 ! pigment granule transport GO:0051904 17 9 0,000 0,05906093 0,11714807 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05906093 0,11705157 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05906093 0,11695523 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05906093 0,11685905 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05906093 0,11676303 ! mitochondrion localization GO:0051646 15 9 0,000 0,05906093 0,11666717 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,06022524 0,1188695 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,06203343 0,12233805 ! kidney development GO:0001822 122 60 1,000 0,06203343 0,12223786 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06540512 0,12877636 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06540512 0,12867106 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06540512 0,12856594 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06540512 0,12846099 ! synapsis GO:0007129 13 10 0,000 0,06540512 0,12835621 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06540512 0,1282516 ! N-glycan processing GO:0006491 20 10 0,000 0,06540512 0,12814716 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06540512 0,12804289 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06540512 0,12793879 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06540512 0,12783486 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06540512 0,1277311 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06540512 0,1276275 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,06540512 0,12752408 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06540512 0,12742082 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06540512 0,12731773 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06540512 0,1272148 ! androgen metabolic process GO:0008209 17 10 0,000 0,06540512 0,12711204 ! phospholipid efflux GO:0033700 16 10 0,000 0,06540512 0,12700945 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06540512 0,12690702 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06540512 0,12680476 ! lung alveolus development GO:0048286 26 10 0,000 0,06540512 0,12670267 ! pathogenesis GO:0009405 13 10 0,000 0,06540512 0,12660073 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06540512 0,12649896 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06540512 0,12639736 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06540512 0,12629592 ! endoderm development GO:0007492 16 10 0,000 0,06540512 0,12619464 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06540512 0,12609352 ! arginine catabolic process GO:0006527 13 10 0,000 0,06540512 0,12599256 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06540512 0,12589177 ! proline metabolic process GO:0006560 13 10 0,000 0,06540512 0,12579114 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06540512 0,12569066 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06540512 0,12559035 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06540512 0,1254902 ! V(D)J recombination GO:0033151 28 10 0,000 0,06540512 0,12539021 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06540512 0,12529037 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06540512 0,1251907 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06540512 0,12509118 ! B cell proliferation GO:0042100 18 10 0,000 0,06540512 0,12499183 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06540512 0,12489263 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06540512 0,12479358 ! multicellular organism growth GO:0035264 18 10 0,000 0,06540512 0,1246947 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06540512 0,12459597 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06540512 0,1244974 ! epithelial cell development GO:0002064 20 10 0,000 0,06540512 0,12439898 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06540512 0,12430072 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06540512 0,12420261 ! macroautophagy GO:0016236 17 10 0,000 0,06540512 0,12410466 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06540512 0,12400686 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06540512 0,12390922 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06540512 0,12381173 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06540512 0,12371439 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06540512 0,12361721 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06540512 0,12352018 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06540512 0,1234233 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06540512 0,12332658 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06540512 0,12323 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06540512 0,12313358 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06540512 0,1230373 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06540512 0,12294118 ! response to dsRNA GO:0043331 20 10 0,000 0,06540512 0,12284521 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06540512 0,12274938 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06540512 0,12265371 ! melanosome localization GO:0032400 16 10 0,000 0,06540512 0,12255819 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06540512 0,12246281 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06540512 0,12236758 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06540512 0,1222725 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06540512 0,12217757 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06540512 0,12208279 ! mRNA cleavage GO:0006379 17 10 0,000 0,06540512 0,12198815 ! protein sumoylation GO:0016925 15 10 0,000 0,06540512 0,12189366 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06540512 0,12179931 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06540512 0,12170511 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06540512 0,12161106 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06540512 0,12151715 ! salivary gland development GO:0007431 27 10 0,000 0,06540512 0,12142339 ! prophase GO:0051324 15 10 0,000 0,06540512 0,12132977 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06540512 0,12123629 ! apical protein localization GO:0045176 15 10 0,000 0,06540512 0,12114296 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06540512 0,12104978 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06540512 0,12095673 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,06540512 0,12086383 ! midbrain development GO:0030901 13 10 0,000 0,06540512 0,12077107 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06540512 0,12067846 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06540512 0,12058598 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06540512 0,12049365 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06540512 0,12040146 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06540512 0,12030941 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06540512 0,1202175 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,06540512 0,12012573 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 0,000 0,06540512 0,1200341 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06540512 0,11994261 ! blastocyst formation GO:0001825 17 10 0,000 0,06540512 0,11985126 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06540512 0,11976005 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06540512 0,11966898 ! activation of innate immune response GO:0002218 12 10 0,000 0,06540512 0,11957805 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06540512 0,11948725 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06540512 0,11939659 ! response to nicotine GO:0035094 20 10 0,000 0,06540512 0,11930607 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06540512 0,11921569 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06540512 0,11912544 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06540512 0,11903533 ! ear development GO:0043583 103 62 1,000 0,06570453 0,11948987 ! gonad development GO:0008406 98 62 1,000 0,06570453 0,11939963 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,06570453 0,11930951 ! detection of external stimulus GO:0009581 91 63 1,000 0,0675668 0,12259858 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,06944644 0,1259142 ! germ cell development GO:0007281 118 65 1,000 0,07134315 0,12925574 ! respiratory burst GO:0045730 17 11 0,000 0,07170673 0,1298167 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,07170673 0,1297191 ! neuron fate specification GO:0048665 17 11 0,000 0,07170673 0,12962164 ! telencephalon cell migration GO:0022029 20 11 0,000 0,07170673 0,12952432 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,07170673 0,12942716 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,07170673 0,12933013 ! thyroid gland development GO:0030878 26 11 0,000 0,07170673 0,12923326 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,07170673 0,12913653 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,07170673 0,12903994 ! response to pain GO:0048265 24 11 0,000 0,07170673 0,1289435 ! T cell proliferation GO:0042098 26 11 0,000 0,07170673 0,1288472 ! blood vessel remodeling GO:0001974 29 11 0,000 0,07170673 0,12875104 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,07170673 0,12865503 ! bone resorption GO:0045453 16 11 0,000 0,07170673 0,12855916 ! ventral spinal cord development GO:0021517 21 11 0,000 0,07170673 0,12846344 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07170673 0,12836786 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07170673 0,12827242 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,07170673 0,12817712 ! melanocyte differentiation GO:0030318 21 11 0,000 0,07170673 0,12808196 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,07170673 0,12798694 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,07170673 0,12789207 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,07170673 0,12779733 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,07170673 0,12770274 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,07170673 0,12760828 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,07170673 0,12751397 ! UV protection GO:0009650 19 11 0,000 0,07170673 0,12741979 ! adult heart development GO:0007512 14 11 0,000 0,07170673 0,12732576 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07170673 0,12723186 ! temperature homeostasis GO:0001659 17 11 0,000 0,07170673 0,1271381 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,07170673 0,12704448 ! negative regulation of ossification GO:0030279 26 11 0,000 0,07170673 0,12695099 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,07170673 0,12685765 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,07170673 0,12676444 ! regulation of organ growth GO:0046620 13 11 0,000 0,07170673 0,12667136 ! pigment granule localization GO:0051875 20 11 0,000 0,07170673 0,12657843 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,07170673 0,12648563 ! vasoconstriction GO:0042310 18 11 0,000 0,07170673 0,12639297 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07170673 0,12630044 ! embryonic axis specification GO:0000578 18 11 0,000 0,07170673 0,12620805 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,07170673 0,12611579 ! snRNA metabolic process GO:0016073 24 11 0,000 0,07170673 0,12602367 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07170673 0,12593168 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,07170673 0,12583982 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,07170673 0,1257481 ! zymogen activation GO:0031638 15 11 0,000 0,07170673 0,12565652 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,07170673 0,12556506 ! neuroblast proliferation GO:0007405 24 11 0,000 0,07170673 0,12547374 ! nucleosome positioning GO:0016584 15 11 0,000 0,07170673 0,12538256 ! regulation of isotype switching GO:0045191 22 11 0,000 0,07170673 0,1252915 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,07170673 0,12520058 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,07170673 0,12510979 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,07170673 0,12501913 ! acid secretion GO:0046717 18 11 0,000 0,07170673 0,1249286 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07170673 0,1248382 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,07170673 0,12474794 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,07170673 0,1246578 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,07170673 0,1245678 ! oocyte differentiation GO:0009994 18 11 0,000 0,07170673 0,12447792 ! thymus development GO:0048538 27 11 0,000 0,07170673 0,12438818 ! cholesterol efflux GO:0033344 19 11 0,000 0,07170673 0,12429856 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,07170673 0,12420907 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07170673 0,12411971 ! germ cell migration GO:0008354 25 11 0,000 0,07170673 0,12403048 ! embryonic gut development GO:0048566 15 11 0,000 0,07170673 0,12394138 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,07170673 0,1238524 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,07170673 0,12376356 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,07170673 0,12367484 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,07170673 0,12358625 ! defense response to fungus GO:0050832 13 11 0,000 0,07170673 0,12349778 ! developmental induction GO:0031128 19 11 0,000 0,07170673 0,12340944 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,07170673 0,12332123 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07170673 0,12323314 ! sequestering of metal ion GO:0051238 14 11 0,000 0,07170673 0,12314518 ! lamellipodium assembly GO:0030032 20 11 0,000 0,07170673 0,12305735 ! regulation of embryonic development GO:0045995 27 11 0,000 0,07170673 0,12296964 ! nucleus localization GO:0051647 19 11 0,000 0,07170673 0,12288205 ! regulation of synapse organization GO:0050807 17 11 0,000 0,07170673 0,12279459 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,07325662 0,12535947 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,07325662 0,12527038 ! cell projection assembly GO:0030031 120 66 1,000 0,07325662 0,1251814 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,07518652 0,12838805 ! lung development GO:0030324 144 67 1,000 0,07518652 0,128297 ! chromosome segregation GO:0007059 113 67 1,000 0,07518652 0,12820607 ! adaptive immune response GO:0002250 119 67 1,000 0,07518652 0,12811528 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,07713256 0,13133825 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 1,000 0,07713256 0,13124536 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07796607 0,13256986 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07796607 0,13247624 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07796607 0,13238275 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,07796607 0,13228939 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07796607 0,13219617 ! virus-host interaction GO:0019048 29 12 0,000 0,07796607 0,13210307 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07796607 0,1320101 ! cartilage condensation GO:0001502 20 12 0,000 0,07796607 0,13191727 ! mating GO:0007618 17 12 0,000 0,07796607 0,13182457 ! protein complex disassembly GO:0043241 27 12 0,000 0,07796607 0,13173199 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07796607 0,13163955 ! hippocampus development GO:0021766 26 12 0,000 0,07796607 0,13154724 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07796607 0,13145505 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07796607 0,131363 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07796607 0,13127107 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07796607 0,13117927 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07796607 0,1310876 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07796607 0,13099606 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07796607 0,13090465 ! drug transport GO:0015893 16 12 0,000 0,07796607 0,13081336 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07796607 0,1307222 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07796607 0,13063117 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07796607 0,13054026 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07796607 0,13044948 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07796607 0,13035883 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07796607 0,1302683 ! forebrain cell migration GO:0021885 21 12 0,000 0,07796607 0,1301779 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07796607 0,13008763 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07796607 0,12999748 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07796607 0,12990745 ! entry into host cell GO:0030260 32 12 0,000 0,07796607 0,12981755 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,07796607 0,12972777 ! monoamine transport GO:0015844 18 12 0,000 0,07796607 0,12963812 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07796607 0,12954859 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07796607 0,12945918 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07796607 0,1293699 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07796607 0,12928074 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07796607 0,12919171 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07796607 0,12910279 ! protein homotetramerization GO:0051289 21 12 0,000 0,07796607 0,129014 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07796607 0,12892533 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07796607 0,12883678 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07796607 0,12874836 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07796607 0,12866005 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07796607 0,12857187 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07796607 0,12848381 ! cranial nerve development GO:0021545 20 12 0,000 0,07796607 0,12839586 ! fucose catabolic process GO:0019317 22 12 0,000 0,07796607 0,12830804 GO:0042355|L-fucose catabolic process, ! histone methylation GO:0016571 26 12 0,000 0,07796607 0,12822034 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07796607 0,12813276 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07796607 0,1280453 ! gland morphogenesis GO:0022612 29 12 0,000 0,07796607 0,12795795 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07796607 0,12787073 ! T cell homeostasis GO:0043029 25 12 0,000 0,07796607 0,12778362 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07796607 0,12769664 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07796607 0,12760977 ! spleen development GO:0048536 22 12 0,000 0,07796607 0,12752302 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,07796607 0,12743638 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07796607 0,12734987 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07796607 0,12726347 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07796607 0,12717719 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07796607 0,12709103 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,07796607 0,12700498 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07796607 0,12691905 ! response to cold GO:0009409 17 12 0,000 0,07796607 0,12683324 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07796607 0,12674754 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07796607 0,12666196 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,07909444 0,12840838 ! urogenital system development GO:0001655 137 69 1,000 0,07909444 0,12832179 ! respiratory tube development GO:0030323 150 70 1,000 0,08107185 0,13144128 ! reproductive structure development GO:0048608 113 71 1,000 0,0830645 0,13458126 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0841834 0,13630233 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0841834 0,13621067 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0841834 0,13611913 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0841834 0,13602772 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,0841834 0,13593642 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0841834 0,13584525 ! lipid localization GO:0010876 28 13 0,000 0,0841834 0,1357542 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,0841834 0,13566327 ! organelle fusion GO:0048284 32 13 0,000 0,0841834 0,13557247 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0841834 0,13548178 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0841834 0,13539122 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0841834 0,13530078 ! endocrine pancreas development GO:0031018 22 13 0,000 0,0841834 0,13521046 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0841834 0,13512026 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0841834 0,13503018 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0841834 0,13494022 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0841834 0,13485038 ! methionine metabolic process GO:0006555 27 13 0,000 0,0841834 0,13476066 ! plasma membrane organization GO:0007009 24 13 0,000 0,0841834 0,13467106 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,0841834 0,13458157 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,0841834 0,13449221 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0841834 0,13440296 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,0841834 0,13431384 ! cytokine metabolic process GO:0042107 22 13 0,000 0,0841834 0,13422483 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,0841834 0,13413594 ! exocrine system development GO:0035272 32 13 0,000 0,0841834 0,13404717 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,0841834 0,13395851 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,0841834 0,13386997 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0841834 0,13378155 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0841834 0,13369325 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,0841834 0,13360506 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0841834 0,13351699 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,0841834 0,13342903 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,0841834 0,13334119 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0841834 0,13325347 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0841834 0,13316586 ! ribosome assembly GO:0042255 17 13 0,000 0,0841834 0,13307836 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0841834 0,13299098 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,0841834 0,13290372 ! chromatin silencing GO:0006342 26 13 0,000 0,0841834 0,13281657 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,0841834 0,13272953 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0841834 0,13264261 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0841834 0,1325558 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,0841834 0,13246911 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,0841834 0,13238253 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,0841834 0,13229606 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0841834 0,1322097 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0841834 0,13212346 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0841834 0,13203733 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,0841834 0,13195131 ! embryonic placenta development GO:0001892 23 13 0,000 0,0841834 0,13186541 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,0841834 0,13177961 ! insulin secretion GO:0030073 23 13 0,000 0,0841834 0,13169393 ! acrosome reaction GO:0007340 18 13 0,000 0,0841834 0,13160836 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,08507209 0,13291133 ! carbohydrate transport GO:0008643 110 72 1,000 0,08507209 0,13282508 ! respiratory system development GO:0060541 153 72 1,000 0,08507209 0,13273894 ! meiosis GO:0007126 121 74 1,000 0,08913096 0,13898191 GO:0051327|M phase of meiotic cell cycle, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,08913096 0,1388919 ! rRNA transcription GO:0009303 25 14 0,000 0,09035902 0,14071443 ! lactation GO:0007595 26 14 0,000 0,09035902 0,14062342 ! reproductive cellular process GO:0048610 20 14 0,000 0,09035902 0,14053252 ! tRNA modification GO:0006400 20 14 0,000 0,09035902 0,14044173 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,09035902 0,14035107 ! water transport GO:0006833 21 14 0,000 0,09035902 0,14026052 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,09035902 0,14017009 ! non-recombinational repair GO:0000726 25 14 0,000 0,09035902 0,14007977 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,09035902 0,13998957 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,09035902 0,13989949 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,09035902 0,13980952 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,09035902 0,13971967 ! RNA polyadenylation GO:0043631 30 14 0,000 0,09035902 0,13962993 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,09035902 0,13954031 ! palate development GO:0060021 31 14 0,000 0,09035902 0,1394508 ! regulated secretory pathway GO:0045055 23 14 0,000 0,09035902 0,13936141 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,09035902 0,13927213 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,09035902 0,13918297 ! arginine metabolic process GO:0006525 17 14 0,000 0,09035902 0,13909392 ! regulation of heart rate GO:0002027 24 14 0,000 0,09035902 0,13900499 ! organic alcohol transport GO:0015850 29 14 0,000 0,09035902 0,13891617 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,09035902 0,13882746 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,09035902 0,13873887 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,09035902 0,13865038 ! neutral amino acid transport GO:0015804 26 14 0,000 0,09035902 0,13856202 ! L-amino acid transport GO:0015807 30 14 0,000 0,09035902 0,13847376 ! bone mineralization GO:0030282 17 14 0,000 0,09035902 0,13838562 ! stem cell development GO:0048864 43 14 0,000 0,09035902 0,13829758 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,09035902 0,13820966 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,09035902 0,13812186 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09035902 0,13803416 ! cerebellum development GO:0021549 21 14 0,000 0,09035902 0,13794657 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,09035902 0,1378591 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,09035902 0,13777174 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,09035902 0,13768449 ! cofactor transport GO:0051181 26 14 0,000 0,09035902 0,13759734 ! NADP metabolic process GO:0006739 24 14 0,000 0,09035902 0,13751031 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,09035902 0,13742339 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,09035902 0,13733658 ! intestinal absorption GO:0050892 25 14 0,000 0,09035902 0,13724987 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,09035902 0,13716328 ! oxygen transport GO:0015671 21 14 0,000 0,09035902 0,1370768 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,09035902 0,13699042 ! male genitalia development GO:0030539 24 14 0,000 0,09035902 0,13690416 ! regulation of RNA stability GO:0043487 32 14 0,000 0,09035902 0,136818 ! regulation of axon extension GO:0030516 37 14 0,000 0,09035902 0,13673195 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,09035902 0,13664601 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,09118167 0,13780345 ! meiotic cell cycle GO:0051321 122 75 1,000 0,09118167 0,13771694 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,09324618 0,14074674 ! regulation of catabolic process GO:0009894 161 76 1,000 0,09324618 0,1406585 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,09532422 0,14370305 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0964932 0,14537422 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0964932 0,14528325 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0964932 0,14519239 ! superoxide anion generation GO:0042554 20 15 0,000 0,0964932 0,14510164 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0964932 0,14501101 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0964932 0,14492049 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0964932 0,14483009 ! copper ion transport GO:0006825 20 15 0,000 0,0964932 0,14473979 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0964932 0,14464961 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0964932 0,14455955 ! sulfate transport GO:0008272 23 15 0,000 0,0964932 0,14446959 ! response to cAMP GO:0051591 22 15 0,000 0,0964932 0,14437975 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0964932 0,14429001 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0964932 0,14420039 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0964932 0,14411088 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0964932 0,14402148 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0964932 0,1439322 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0964932 0,14384302 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0964932 0,14375395 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0964932 0,14366499 ! pituitary gland development GO:0021983 29 15 0,000 0,0964932 0,14357615 ! vesicle coating GO:0006901 33 15 0,000 0,0964932 0,14348741 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0964932 0,14339878 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0964932 0,14331027 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0964932 0,14322186 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0964932 0,14313356 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0964932 0,14304537 ! histone deacetylation GO:0016575 20 15 0,000 0,0964932 0,14295729 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0964932 0,14286931 ! tissue regeneration GO:0042246 26 15 0,000 0,0964932 0,14278145 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0964932 0,14269369 ! water homeostasis GO:0030104 27 15 0,000 0,0964932 0,14260604 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0964932 0,1425185 ! muscle maintenance GO:0046716 26 15 0,000 0,0964932 0,14243106 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0964932 0,14234373 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0964932 0,14225651 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0964932 0,1421694 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0964932 0,14208239 ! cell killing GO:0001906 29 15 0,000 0,0964932 0,14199549 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0964932 0,1419087 ! detection of bacterium GO:0016045 18 15 0,000 0,0964932 0,14182201 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0964932 0,14173543 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0964932 0,14164895 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0964932 0,14156258 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0964932 0,14147631 ! peptide hormone processing GO:0016486 23 15 0,000 0,0964932 0,14139015 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,09741552 0,14265474 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,09741552 0,14256797 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,0995198 0,14555905 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,1016368 0,14856509 ! muscle cell differentiation GO:0042692 159 80 1,000 0,1016368 0,14847489 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,1016368 0,14838479 ! protein import into nucleus GO:0006606 158 80 1,000 0,1016368 0,14829481 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,10258621 0,14958935 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,10258621 0,14949874 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,10258621 0,14940824 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,10258621 0,14931786 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,10258621 0,14922758 ! bone remodeling GO:0046849 27 16 0,000 0,10258621 0,14913741 ! filopodium assembly GO:0046847 32 16 0,000 0,10258621 0,14904736 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,10258621 0,14895741 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,10258621 0,14886756 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,10258621 0,14877783 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,10258621 0,14868821 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,10258621 0,14859869 ! startle response GO:0001964 28 16 0,000 0,10258621 0,14850928 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,10258621 0,14841998 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,10258621 0,14833078 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,10258621 0,14824169 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,10258621 0,14815271 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,10258621 0,14806384 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,10258621 0,14797507 ! glutamate metabolic process GO:0006536 22 16 0,000 0,10258621 0,14788641 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,10258621 0,14779786 ! response to osmotic stress GO:0006970 25 16 0,000 0,10258621 0,14770941 ! lysosomal transport GO:0007041 26 16 0,000 0,10258621 0,14762106 ! fructose metabolic process GO:0006000 25 16 0,000 0,10258621 0,14753283 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10258621 0,1474447 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,10258621 0,14735667 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,10258621 0,14726875 ! negative regulation of immune response GO:0050777 35 16 0,000 0,10258621 0,14718093 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,10258621 0,14709322 ! DNA replication initiation GO:0006270 27 16 0,000 0,10258621 0,14700561 ! neuron recognition GO:0008038 35 16 0,000 0,10258621 0,14691811 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,10258621 0,14683071 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,10258621 0,14674341 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,10258621 0,14665622 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,10258621 0,14656913 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,10258621 0,14648215 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,10258621 0,14639527 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,10258621 0,14630849 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,10258621 0,14622181 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10258621 0,14613524 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,10258621 0,14604877 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,10258621 0,1459624 ! defense response to virus GO:0051607 37 16 0,000 0,10258621 0,14587614 ! response to hypoxia GO:0001666 171 81 1,000 0,10376625 0,14746698 ! nuclear import GO:0051170 161 81 1,000 0,10376625 0,14737993 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,10590789 0,15033297 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,10590789 0,15024433 ! response to oxygen levels GO:0070482 176 83 1,000 0,10806146 0,15320912 ! regulation of lyase activity GO:0051339 160 83 1,000 0,10806146 0,15311889 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,10863833 0,15384569 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,10863833 0,1537552 ! metencephalon development GO:0022037 30 17 0,000 0,10863833 0,1536648 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10863833 0,15357452 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,10863833 0,15348434 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10863833 0,15339427 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10863833 0,1533043 ! inositol metabolic process GO:0006020 28 17 0,000 0,10863833 0,15321444 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10863833 0,15312468 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10863833 0,15303503 ! glial cell development GO:0021782 27 17 0,000 0,10863833 0,15294548 ! limbic system development GO:0021761 36 17 0,000 0,10863833 0,15285604 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10863833 0,1527667 ! adult walking behavior GO:0007628 33 17 0,000 0,10863833 0,15267747 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10863833 0,15258834 ! heart looping GO:0001947 30 17 0,000 0,10863833 0,15249932 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,10863833 0,1524104 ! myoblast differentiation GO:0045445 45 17 0,000 0,10863833 0,15232158 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,10863833 0,15223287 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,10863833 0,15214426 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10863833 0,15205575 ! glycine metabolic process GO:0006544 28 17 0,000 0,10863833 0,15196734 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,10863833 0,15187904 ! NAD metabolic process GO:0019674 29 17 0,000 0,10863833 0,15179084 ! membrane budding GO:0006900 37 17 0,000 0,10863833 0,15170275 ! DNA integration GO:0015074 29 17 0,000 0,10863833 0,15161475 ! regulation of protein binding GO:0043393 33 17 0,000 0,10863833 0,15152686 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10863833 0,15143907 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10863833 0,15135138 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,10863833 0,15126379 ! genitalia development GO:0048806 30 17 0,000 0,10863833 0,15117631 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10863833 0,15108892 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,10863833 0,15100164 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10863833 0,15091445 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,10863833 0,15082737 ! steroid catabolic process GO:0006706 31 17 0,000 0,10863833 0,15074039 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,10863833 0,15065351 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,10863833 0,15056672 ! gas transport GO:0015669 25 17 0,000 0,10863833 0,15048004 ! organic cation transport GO:0015695 31 17 0,000 0,10863833 0,15039346 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,10863833 0,15030698 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,10863833 0,15022059 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,10863833 0,15013431 ! microspike assembly GO:0030035 36 17 0,000 0,10863833 0,15004812 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,1102267 0,15215459 ! hemostasis GO:0007599 158 84 1,000 0,1102267 0,15206735 ! regulation of ligase activity GO:0051340 142 84 1,000 0,1102267 0,1519802 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,11240337 0,15489262 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,11240337 0,15480396 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,11459121 0,1577268 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,11464984 0,15771728 ! neuron maturation GO:0042551 42 18 0,000 0,11464984 0,15762716 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,11464984 0,15753713 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,11464984 0,15744722 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,11464984 0,1573574 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,11464984 0,15726769 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,11464984 0,15717808 ! memory GO:0007613 31 18 0,000 0,11464984 0,15708857 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11464984 0,15699916 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,11464984 0,15690985 ! patterning of blood vessels GO:0001569 39 18 0,000 0,11464984 0,15682065 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,11464984 0,15673155 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,11464984 0,15664255 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,11464984 0,15655364 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,11464984 0,15646485 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11464984 0,15637615 ! response to retinoic acid GO:0032526 26 18 0,000 0,11464984 0,15628755 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,11464984 0,15619905 ! response to fungus GO:0009620 21 18 0,000 0,11464984 0,15611065 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,11464984 0,15602235 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,11464984 0,15593416 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,11464984 0,15584606 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,11464984 0,15575806 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,11464984 0,15567016 ! vitamin transport GO:0051180 27 18 0,000 0,11464984 0,15558236 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,11464984 0,15549466 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,11464984 0,15540705 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,11464984 0,15531955 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,11464984 0,15523215 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,11464984 0,15514484 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,11464984 0,15505763 ! nerve development GO:0021675 28 18 0,000 0,11464984 0,15497052 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,11464984 0,15488351 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,11678997 0,15768612 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,11678997 0,15759768 ! regulation of protein transport GO:0051223 154 87 1,000 0,11678997 0,15750934 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 206 88 1,000 0,11899941 0,16039921 ! protein secretion GO:0009306 39 19 0,000 0,12062101 0,16249392 ! positive regulation of translation GO:0045727 30 19 0,000 0,12062101 0,16240299 ! negative regulation of defense response GO:0031348 25 19 0,000 0,12062101 0,16231216 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,12062101 0,16222143 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,12062101 0,16213081 ! skin development GO:0043588 36 19 0,000 0,12062101 0,16204028 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,12062101 0,16194986 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,12062101 0,16185953 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,12062101 0,16176931 ! bile acid metabolic process GO:0008206 29 19 0,000 0,12062101 0,16167919 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,12062101 0,16158917 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,12062101 0,16149925 ! cerebral cortex development GO:0021987 36 19 0,000 0,12062101 0,16140942 ! response to vitamin A GO:0033189 27 19 0,000 0,12062101 0,1613197 ! heme metabolic process GO:0042168 36 19 0,000 0,12062101 0,16123008 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,12062101 0,16114056 ! plasma membrane fusion GO:0045026 28 19 0,000 0,12062101 0,16105113 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,12062101 0,16096181 ! peptide cross-linking GO:0018149 37 19 0,000 0,12062101 0,16087259 ! protein export from nucleus GO:0006611 36 19 0,000 0,12062101 0,16078346 ! heart process GO:0003015 30 19 0,000 0,12062101 0,16069443 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,12062101 0,1606055 ! visual learning GO:0008542 36 19 0,000 0,12062101 0,16051667 ! cellular pigmentation GO:0033059 36 19 0,000 0,12062101 0,16042794 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,12062101 0,16033931 ! cell-cell junction organization GO:0045216 35 19 0,000 0,12062101 0,16025077 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,12062101 0,16016233 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,12062101 0,16007399 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,12062101 0,15998575 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,12062101 0,1598976 ! cilium assembly GO:0042384 37 19 0,000 0,12062101 0,15980955 ! peptide hormone secretion GO:0030072 31 19 0,000 0,12062101 0,1597216 ! ossification GO:0001503 188 90 1,000 0,12344936 0,16337688 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,12344936 0,16328706 ! sex differentiation GO:0007548 145 90 1,000 0,12344936 0,16319734 ! bone development GO:0060348 189 91 1,000 0,1256894 0,16606738 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,1265521 0,16711545 ! positive regulation of ossification GO:0045778 47 20 0,000 0,1265521 0,16702378 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,1265521 0,16693221 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,1265521 0,16684074 ! cAMP metabolic process GO:0046058 36 20 0,000 0,1265521 0,16674937 ! response to vitamin GO:0033273 31 20 0,000 0,1265521 0,1666581 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,1265521 0,16656693 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,1265521 0,16647586 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,1265521 0,16638489 ! retinoid metabolic process GO:0001523 32 20 0,000 0,1265521 0,16629402 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,1265521 0,16620325 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,1265521 0,16611257 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,1265521 0,166022 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,1265521 0,16593152 GO:0032392|DNA geometric change, ! D-ribose metabolic process GO:0006014 29 20 0,000 0,1265521 0,16584115 ! body fluid secretion GO:0007589 31 20 0,000 0,1265521 0,16575087 ! peptide secretion GO:0002790 35 20 0,000 0,1265521 0,16566069 ! stem cell differentiation GO:0048863 53 20 0,000 0,1265521 0,16557061 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,1265521 0,16548062 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,1265521 0,16539074 ! sensory perception of pain GO:0019233 30 20 0,000 0,1265521 0,16530095 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,1265521 0,16521126 ! diencephalon development GO:0021536 34 20 0,000 0,1265521 0,16512166 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,1265521 0,16503217 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,1265521 0,16494277 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,1265521 0,16485346 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,1265521 0,16476426 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,1265521 0,16467515 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,1265521 0,16458613 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,1265521 0,16449722 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,1265521 0,16440839 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,1265521 0,16431967 ! actin filament-based movement GO:0030048 43 20 0,000 0,1265521 0,16423104 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,1265521 0,1641425 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,1265521 0,16405407 ! negative regulation of translation GO:0017148 29 20 0,000 0,1265521 0,16396572 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,1265521 0,16387747 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,13019842 0,16850856 ! regulation of membrane potential GO:0042391 164 93 1,000 0,13019842 0,16841796 ! regulation of cell killing GO:0031341 42 21 0,000 0,13244338 0,17122986 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,13244338 0,1711379 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,13244338 0,17104604 ! hormone secretion GO:0046879 38 21 0,000 0,13244338 0,17095428 ! glycerol metabolic process GO:0006071 34 21 0,000 0,13244338 0,17086261 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,13244338 0,17077105 ! axis specification GO:0009798 38 21 0,000 0,13244338 0,17067958 ! ovarian follicle development GO:0001541 35 21 0,000 0,13244338 0,17058821 ! smooth muscle contraction GO:0006939 46 21 0,000 0,13244338 0,17049693 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,13244338 0,17040576 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,13244338 0,17031468 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,13244338 0,1702237 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,13244338 0,17013282 ! cytolysis GO:0019835 24 21 0,000 0,13244338 0,17004203 ! vasodilation GO:0042311 39 21 0,000 0,13244338 0,16995134 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,13244338 0,16986075 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,13244338 0,16977026 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,13244338 0,16967986 ! oogenesis GO:0048477 36 21 0,000 0,13244338 0,16958955 ! collagen fibril organization GO:0030199 59 21 0,000 0,13244338 0,16949935 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,13244338 0,16940924 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,13244338 0,16931922 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,13244338 0,1692293 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,13244338 0,16913948 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,13244338 0,16904975 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,13244338 0,16896011 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,13244338 0,16887057 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,13244338 0,16878113 ! collagen catabolic process GO:0030574 28 21 0,000 0,13244338 0,16869178 ! sperm-egg recognition GO:0035036 21 21 0,000 0,13244338 0,16860252 ! gut development GO:0048565 39 21 0,000 0,13244338 0,16851336 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,13829512 0,17586578 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,13829512 0,17577288 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,13829512 0,17568007 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,13829512 0,17558737 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,13829512 0,17549476 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,13829512 0,17540225 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,13829512 0,17530983 ! regeneration GO:0031099 41 22 0,000 0,13829512 0,17521751 ! keratinization GO:0031424 28 22 0,000 0,13829512 0,17512529 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,13829512 0,17503317 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,13829512 0,17494115 ! sensory perception of taste GO:0050909 28 22 0,000 0,13829512 0,17484922 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,13829512 0,17475738 ! vacuolar transport GO:0007034 36 22 0,000 0,13829512 0,17466565 ! lysosome organization GO:0007040 41 22 0,000 0,13829512 0,17457401 ! central nervous system neuron development GO:0021954 46 22 0,000 0,13829512 0,17448246 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,13829512 0,17439102 ! fucose metabolic process GO:0006004 39 22 0,000 0,13829512 0,17429966 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,13829512 0,17420841 ! ureteric bud development GO:0001657 43 22 0,000 0,13829512 0,17411725 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,13829512 0,17402618 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,13829512 0,17393521 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,13829512 0,17384434 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,13829512 0,17375356 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,13829512 0,17366287 ! sarcomere organization GO:0045214 30 22 0,000 0,13829512 0,17357228 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,13829512 0,17348178 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,13829512 0,17339138 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,13829512 0,17330107 ! regulation of protein localization GO:0032880 176 97 1,000 0,1393259 0,17450188 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,14162926 0,17729449 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 1,000 0,14394079 0,18009441 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,14394079 0,1800008 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,14410758 0,18011576 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,14410758 0,18002225 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,14410758 0,17992883 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,14410758 0,1798355 ! gluconeogenesis GO:0006094 33 23 0,000 0,14410758 0,17974227 ! viral genome replication GO:0019079 41 23 0,000 0,14410758 0,17964914 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,14410758 0,17955611 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,14410758 0,17946317 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,14410758 0,17937033 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,14410758 0,17927758 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,14410758 0,17918493 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,14410758 0,17909238 ! visual behavior GO:0007632 42 23 0,000 0,14410758 0,17899992 ! response to ethanol GO:0045471 46 23 0,000 0,14410758 0,17890756 ! peroxisome organization GO:0007031 37 23 0,000 0,14410758 0,17881529 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,14410758 0,17872312 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,14410758 0,17863104 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,14410758 0,17853906 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,14410758 0,17844717 GO:0051693|actin filament capping, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,14410758 0,17835537 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,14410758 0,17826367 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,14410758 0,17817207 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,14410758 0,17808056 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,14410758 0,17798914 ! fatty acid transport GO:0015908 44 23 0,000 0,14410758 0,17789782 ! platelet activation GO:0030168 37 23 0,000 0,14410758 0,17780659 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,14410758 0,17771545 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,14410758 0,17762441 ! hormone transport GO:0009914 40 23 0,000 0,14410758 0,17753346 ! cell-cell recognition GO:0009988 25 23 0,000 0,14410758 0,1774426 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,14410758 0,17735184 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,14410758 0,17726117 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,14410758 0,17717059 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,14410758 0,17708011 ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,14988103 0,18408053 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,14988103 0,18398661 ! vesicle docking GO:0048278 47 24 0,000 0,14988103 0,18389279 ! spinal cord development GO:0021510 47 24 0,000 0,14988103 0,18379906 ! vacuole organization GO:0007033 43 24 0,000 0,14988103 0,18370543 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,14988103 0,1836119 ! digestive system process GO:0022600 39 24 0,000 0,14988103 0,18351846 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,14988103 0,18342511 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,14988103 0,18333186 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,14988103 0,1832387 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,14988103 0,18314564 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,14988103 0,18305267 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,14988103 0,1829598 ! membrane depolarization GO:0051899 39 24 0,000 0,14988103 0,18286702 ! pallium development GO:0021543 49 24 0,000 0,14988103 0,18277434 ! pentose metabolic process GO:0019321 35 24 0,000 0,14988103 0,18268174 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,14988103 0,18258925 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,14988103 0,18249684 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,14988103 0,18240453 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,14988103 0,18231232 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,14988103 0,18222019 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,14988103 0,18212816 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,14988103 0,18203623 ! regulation of amine transport GO:0051952 40 24 0,000 0,14988103 0,18194438 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,15561573 0,18881061 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,15561573 0,18871544 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,15561573 0,18862037 ! phototransduction GO:0007602 33 25 0,000 0,15561573 0,1885254 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,15561573 0,18843052 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,15561573 0,18833573 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,15561573 0,18824104 ! osteoblast differentiation GO:0001649 60 25 0,000 0,15561573 0,18814645 ! neural crest cell development GO:0014032 54 25 0,000 0,15561573 0,18805195 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,15561573 0,18795755 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,15561573 0,18786324 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,15561573 0,18776903 ! interaction with host GO:0051701 62 25 0,000 0,15561573 0,18767491 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,15561573 0,18758088 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,15561573 0,18748695 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,15561573 0,18739311 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,15561573 0,18729937 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,15561573 0,18720572 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,15561573 0,18711216 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,15561573 0,1870187 ! telomere organization GO:0032200 43 25 0,000 0,15561573 0,18692533 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,15561573 0,18683206 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,16131193 0,19357431 ! embryonic pattern specification GO:0009880 44 26 0,000 0,16131193 0,19347781 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,16131193 0,19338141 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,16131193 0,19328511 ! initiation of viral infection GO:0019059 57 26 0,000 0,16131193 0,1931889 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,16131193 0,19309278 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,16131193 0,19299676 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,16131193 0,19290084 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,16131193 0,19280501 ! molting cycle process GO:0022404 50 26 0,000 0,16131193 0,19270928 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,16131193 0,19261364 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,16131193 0,1925181 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,16131193 0,19242265 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,16131193 0,1923273 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,16131193 0,19223204 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,16131193 0,19213688 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,16131193 0,19204181 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,16131193 0,19194683 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,16131193 0,19185195 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,16131193 0,19175716 ! blastocyst development GO:0001824 49 26 0,000 0,16131193 0,19166247 ! leukocyte proliferation GO:0070661 52 26 0,000 0,16131193 0,19156786 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,16131193 0,19147336 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,16131193 0,19137894 ! neuron fate commitment GO:0048663 48 27 0,000 0,16696989 0,19799386 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,16696989 0,19789633 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,16696989 0,19779889 ! iron ion transport GO:0006826 59 27 0,000 0,16696989 0,19770155 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,16696989 0,1976043 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,16696989 0,19750715 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,16696989 0,1974101 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,16696989 0,19731314 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,16696989 0,19721627 ! autophagy GO:0006914 41 27 0,000 0,16696989 0,1971195 ! response to toxin GO:0009636 47 27 0,000 0,16696989 0,19702283 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,16696989 0,19692625 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,16696989 0,19682976 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,16696989 0,19673337 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,16696989 0,19663708 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,16696989 0,19654087 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,17258986 0,20305683 ! circadian rhythm GO:0007623 50 28 0,000 0,17258986 0,20295758 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,17258986 0,20285843 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,17258986 0,20275938 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,17258986 0,20266042 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,17258986 0,20256157 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,17258986 0,2024628 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,17258986 0,20236414 ! synaptogenesis GO:0007416 42 28 0,000 0,17258986 0,20226557 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,17258986 0,20216709 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,17258986 0,20206872 ! translational initiation GO:0006413 65 29 0,000 0,17817211 0,20850297 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,17817211 0,2084016 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,17817211 0,20830034 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,17817211 0,20819917 ! catechol metabolic process GO:0009712 54 29 0,000 0,17817211 0,20809811 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,17817211 0,20799714 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,17817211 0,20789626 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,17817211 0,20779549 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,17817211 0,20769481 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,17817211 0,20759424 ! cell fate determination GO:0001709 60 29 0,000 0,17817211 0,20749376 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,17817211 0,20739337 ! detection of light stimulus GO:0009583 38 29 0,000 0,17817211 0,20729308 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,17817211 0,20719289 ! tissue homeostasis GO:0001894 48 29 0,000 0,17817211 0,2070928 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,17817211 0,2069928 ! phenol metabolic process GO:0018958 55 30 0,000 0,18371688 0,21333148 ! zinc ion transport GO:0006829 45 30 0,000 0,18371688 0,21322857 ! membrane docking GO:0022406 61 30 0,000 0,18371688 0,21312576 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,18371688 0,21302304 ! regulation of innate immune response GO:0045088 51 30 0,000 0,18371688 0,21292043 ! acute-phase response GO:0006953 49 30 0,000 0,18371688 0,21281792 ! myofibril assembly GO:0030239 47 30 0,000 0,18371688 0,2127155 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,18371688 0,21261319 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,18371688 0,21251097 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,18371688 0,21240885 ! phospholipid transport GO:0015914 51 30 0,000 0,18371688 0,21230683 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,18371688 0,2122049 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,18371688 0,21210308 ! eye morphogenesis GO:0048592 60 30 0,000 0,18371688 0,21200135 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,18922443 0,21825214 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,18922443 0,21814756 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,18922443 0,21804309 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,18922443 0,21793871 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,18922443 0,21783443 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,18922443 0,21773026 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,18922443 0,21762618 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,18922443 0,2175222 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,18922443 0,21741832 ! ovulation cycle process GO:0022602 49 31 0,000 0,18922443 0,21731454 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,18922443 0,21721086 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,18922443 0,21710728 ! peptide transport GO:0015833 55 31 0,000 0,18922443 0,2170038 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,18922443 0,21690041 ! mesoderm formation GO:0001707 69 31 0,000 0,18922443 0,21679713 ! natural killer cell activation GO:0030101 45 31 0,000 0,18922443 0,21669394 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,18922443 0,21659085 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,18922443 0,21648786 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,18922443 0,21638497 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,19469499 0,22253499 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,19469499 0,22242932 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,19469499 0,22232375 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,19469499 0,22221829 ! cholesterol transport GO:0030301 56 32 0,000 0,19469499 0,22211292 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,19469499 0,22200765 ! spliceosome assembly GO:0000245 67 32 0,000 0,19469499 0,22190249 ! spindle organization GO:0007051 46 32 0,000 0,19469499 0,22179742 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,19469499 0,22169245 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,19469499 0,22158758 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,19469499 0,22148281 ! muscle cell development GO:0055001 49 32 0,000 0,19469499 0,22137814 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,19469499 0,22127357 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,19469499 0,2211691 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,19469499 0,22106472 ! ovulation cycle GO:0042698 51 32 0,000 0,19469499 0,22096045 ! BMP signaling pathway GO:0030509 64 32 0,000 0,19469499 0,22085627 ! hindbrain development GO:0030902 61 32 0,000 0,19469499 0,22075219 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,19469499 0,22064821 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,19469499 0,22054433 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,19469499 0,22044054 ! gene silencing GO:0016458 65 32 0,000 0,19469499 0,22033685 ! post-embryonic development GO:0009791 69 33 0,000 0,20012883 0,22637986 ! protein targeting to membrane GO:0006612 68 33 0,000 0,20012883 0,22627347 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,20012883 0,22616719 ! ceramide metabolic process GO:0006672 64 33 0,000 0,20012883 0,22606101 ! formation of primary germ layer GO:0001704 72 33 0,000 0,20012883 0,22595493 ! cell fate specification GO:0001708 52 33 0,000 0,20012883 0,22584895 ! sterol transport GO:0015918 57 33 0,000 0,20012883 0,22574306 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,20012883 0,22563728 ! adult locomotory behavior GO:0008344 59 33 0,000 0,20012883 0,22553159 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,20012883 0,22542601 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,20552617 0,23139727 ! glial cell differentiation GO:0010001 63 34 0,000 0,20552617 0,23128904 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,20552617 0,23118091 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,20552617 0,23107289 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,20552617 0,23096496 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,20552617 0,23085713 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,20552617 0,23074941 ! spermatid development GO:0007286 63 34 0,000 0,20552617 0,23064178 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,20552617 0,23053425 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,20552617 0,23042683 ! placenta development GO:0001890 53 34 0,000 0,20552617 0,2303195 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,20552617 0,23021228 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,21088728 0,2361074 ! negative regulation of secretion GO:0051048 63 35 0,000 0,21088728 0,23599758 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,21088728 0,23588787 ! odontogenesis GO:0042476 66 35 0,000 0,21088728 0,23577825 ! female gonad development GO:0008585 58 35 0,000 0,21088728 0,23566874 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,21088728 0,23555933 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,21088728 0,23545002 ! cytokine production GO:0001816 59 35 0,000 0,21088728 0,23534082 ! vesicle localization GO:0051648 64 35 0,000 0,21088728 0,23523171 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,21621239 0,24105978 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,21621239 0,24094813 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,21621239 0,24083658 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,21621239 0,24072513 ! positive regulation of cell development GO:0010720 80 36 0,000 0,21621239 0,24061379 ! regulation of proteolysis GO:0030162 72 36 0,000 0,21621239 0,24050255 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,21621239 0,24039141 ! aerobic respiration GO:0009060 55 36 0,000 0,21621239 0,24028037 ! embryonic organ development GO:0048568 57 36 0,000 0,21621239 0,24016944 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,21621239 0,24005861 ! RNA export from nucleus GO:0006405 56 37 0,000 0,22150174 0,24581789 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,22150174 0,24570456 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,22150174 0,24559133 ! sister chromatid segregation GO:0000819 58 37 0,000 0,22150174 0,2454782 ! actomyosin structure organization GO:0031032 62 37 0,000 0,22150174 0,24536518 ! organic anion transport GO:0015711 68 37 0,000 0,22150174 0,24525227 ! tissue remodeling GO:0048771 76 37 0,000 0,22150174 0,24513946 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,22150174 0,24502675 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,22150174 0,24491415 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,22150174 0,24480164 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,22150174 0,24468925 ! spermatid differentiation GO:0048515 66 37 0,000 0,22150174 0,24457695 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,22675557 0,25026325 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,22675557 0,25014851 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,22675557 0,25003386 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,22675557 0,24991933 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,22675557 0,2498049 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,22675557 0,24969057 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,22675557 0,24957635 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,22675557 0,24946223 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,22675557 0,24934821 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,22675557 0,2492343 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,22675557 0,2491205 ! mRNA catabolic process GO:0006402 71 39 0,000 0,23197411 0,25473743 ! organic ether metabolic process GO:0018904 55 39 0,000 0,23197411 0,25462122 ! ion transmembrane transport GO:0034220 66 39 0,000 0,23197411 0,25450511 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,23197411 0,25438911 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,23197411 0,25427322 ! RNA modification GO:0009451 57 39 0,000 0,23197411 0,25415743 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,23197411 0,25404174 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,23715761 0,25960019 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,23715761 0,25948213 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,23715761 0,25936418 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,23715761 0,25924635 ! mesenchymal cell development GO:0014031 87 40 0,000 0,23715761 0,25912861 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,23715761 0,25901099 ! cytokinesis GO:0000910 72 40 0,000 0,23715761 0,25889347 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,24230629 0,26439408 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,24230629 0,26427423 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,24230629 0,26415448 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,24230629 0,26403485 ! gliogenesis GO:0042063 88 41 0,000 0,24230629 0,26391532 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,24230629 0,2637959 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,24230629 0,26367659 ! female gamete generation GO:0007292 61 41 0,000 0,24230629 0,26355739 ! polyol metabolic process GO:0019751 66 41 0,000 0,24230629 0,26343829 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,24230629 0,26331931 ! regulation of tube size GO:0035150 71 42 0,000 0,2474204 0,26875552 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,2474204 0,26863424 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,2474204 0,26851307 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,2474204 0,26839201 ! regulation of protein secretion GO:0050708 71 42 0,000 0,2474204 0,26827106 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,25250015 0,27365557 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,25250015 0,27353236 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,25250015 0,27340926 ! striated muscle contraction GO:0006941 77 43 0,000 0,25250015 0,27328627 ! phagocytosis GO:0006909 90 43 0,000 0,25250015 0,27316339 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,25250015 0,27304062 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,25754579 0,2783716 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,25754579 0,2782466 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,25754579 0,27812171 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,25754579 0,27799694 ! developmental growth GO:0048589 82 44 0,000 0,25754579 0,27787228 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,26255754 0,28315259 ! glycolysis GO:0006096 65 45 0,000 0,26255754 0,28302573 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,26255754 0,28289898 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,26255754 0,28277235 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,26255754 0,28264583 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,26255754 0,28251942 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,26255754 0,28239313 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,26255754 0,28226695 ! cell growth GO:0016049 84 45 0,000 0,26255754 0,28214088 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,26753562 0,28736192 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,26753562 0,28723369 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,26753562 0,28710557 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,27248026 0,29228154 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,27248026 0,29215129 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,27248026 0,29202116 ! JNK cascade GO:0007254 91 47 0,000 0,27248026 0,29189114 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,27248026 0,29176124 ! Notch signaling pathway GO:0007219 96 48 0,000 0,27739168 0,29688807 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,27739168 0,29675606 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,27739168 0,29662417 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,27739168 0,2964924 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,28227011 0,30157277 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,28227011 0,30143892 ! regulation of ion transport GO:0043269 77 49 0,000 0,28227011 0,30130518 ! endocrine system development GO:0035270 104 49 0,000 0,28227011 0,30117157 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,28227011 0,30103807 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,28227011 0,30090469 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,28711576 0,30593469 ! neuromuscular process GO:0050905 99 50 0,000 0,28711576 0,30579926 ! regulation of ossification GO:0030278 117 50 0,000 0,28711576 0,30566395 ! inner ear development GO:0048839 79 50 0,000 0,28711576 0,30552876 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,28711576 0,30539369 ! viral infectious cycle GO:0019058 99 51 0,000 0,29192887 0,31037598 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,29192887 0,31023889 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,29192887 0,31010192 ! excretion GO:0007588 83 51 0,000 0,29192887 0,30996507 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,29192887 0,30982834 ! chromatin remodeling GO:0006338 109 51 0,000 0,29192887 0,30969173 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,29192887 0,30955524 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,29192887 0,30941888 ! vesicle organization GO:0016050 107 51 0,000 0,29192887 0,30928263 ! regulation of cell shape GO:0008360 125 51 0,000 0,29192887 0,3091465 ! membrane fusion GO:0006944 110 52 0,000 0,29670963 0,31407099 ! positive regulation of growth GO:0045927 90 52 0,000 0,29670963 0,31393288 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,29670963 0,31379489 ! amino acid activation GO:0043038 92 52 0,000 0,29670963 0,31365702 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,30145827 0,31853694 ! RNA catabolic process GO:0006401 93 53 0,000 0,30145827 0,3183971 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,30145827 0,31825739 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,30145827 0,31811781 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,30145827 0,31797834 ! cell maturation GO:0048469 100 53 0,000 0,30145827 0,317839 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,30145827 0,31769978 ! cell recognition GO:0008037 85 54 0,000 0,30617501 0,32252937 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,30617501 0,32238821 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,30617501 0,32224719 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,30617501 0,32210628 ! chloride transport GO:0006821 90 55 0,000 0,31086005 0,32689217 ! glucose catabolic process GO:0006007 82 55 0,000 0,31086005 0,32674936 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,31086005 0,32660667 ! gastrulation GO:0007369 112 55 0,000 0,31086005 0,32646411 ! heart morphogenesis GO:0003007 97 55 0,000 0,31086005 0,32632168 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,31086005 0,32617937 ! RNA elongation GO:0006354 79 55 0,000 0,31086005 0,32603718 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,31086005 0,32589511 ! regulation of actin filament length GO:0030832 105 56 0,000 0,31551362 0,33062969 ! sensory perception of smell GO:0007608 80 56 0,000 0,31551362 0,33048575 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,31551362 0,33034193 ! proton transport GO:0015992 94 56 0,000 0,31551362 0,33019824 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,31551362 0,33005468 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,32013591 0,33474446 ! hydrogen transport GO:0006818 97 58 0,000 0,32472714 0,3393977 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,32472714 0,33925032 ! regulation of endocytosis GO:0030100 91 58 0,000 0,32472714 0,33910308 ! adult behavior GO:0030534 99 58 0,000 0,32472714 0,33895596 ! positive regulation of secretion GO:0051047 95 59 0,000 0,32928752 0,34356711 ! regulation of cellular component size GO:0032535 109 59 0,000 0,32928752 0,34341819 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,32928752 0,3432694 GO:0032313|regulation of Rab GTPase activity, ! establishment of organelle localization GO:0051656 109 59 0,000 0,32928752 0,34312073 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,33381725 0,34769017 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,33831653 0,35222396 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,33831653 0,35207162 ! mesoderm development GO:0007498 119 61 0,000 0,33831653 0,3519194 ! tRNA processing GO:0008033 89 61 0,000 0,33831653 0,35176732 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,33831653 0,35161537 ! viral reproductive process GO:0022415 126 62 0,000 0,34278558 0,35610627 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,34278558 0,35595257 ! regulation of mitosis GO:0007088 105 63 0,000 0,3472246 0,36040655 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,3472246 0,36025113 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,3472246 0,36009585 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,35163377 0,36451136 ! cell redox homeostasis GO:0045454 102 64 0,000 0,35163377 0,36435438 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,35163377 0,36419753 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,35163377 0,36404082 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,35601331 0,36841636 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,35601331 0,36825797 ! extracellular matrix organization GO:0030198 133 66 0,000 0,36036342 0,3725975 ! secondary metabolic process GO:0019748 116 66 0,000 0,36036342 0,37243745 ! developmental maturation GO:0021700 116 66 0,000 0,36036342 0,37227754 ! activation of MAPK activity GO:0000187 115 67 0,000 0,36468428 0,37657956 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,36468428 0,37641801 ! hexose catabolic process GO:0019320 104 67 0,000 0,36468428 0,37625659 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,36468428 0,37609532 ! amino acid transport GO:0006865 125 68 0,000 0,3689761 0,38035839 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,3689761 0,3801955 ! viral reproduction GO:0016032 134 68 0,000 0,3689761 0,38003274 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,3689761 0,37987013 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,3689761 0,37970765 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,37323906 0,38393039 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,37323906 0,38376632 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,37323906 0,38360239 ! antigen processing and presentation GO:0019882 104 69 0,000 0,37323906 0,38343859 ! amine catabolic process GO:0009310 117 71 0,000 0,38167921 0,39194203 ! humoral immune response GO:0006959 109 71 0,000 0,38167921 0,39177482 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,38167921 0,39160775 ! regulation of immune effector process GO:0002697 137 71 0,000 0,38167921 0,39144083 ! acute inflammatory response GO:0002526 113 72 0,000 0,38585678 0,39555663 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,38585678 0,39538816 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,38585678 0,39521984 ! regulation of blood pressure GO:0008217 125 73 0,000 0,39000625 0,39930002 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,39000625 0,39913018 ! fertilization GO:0009566 90 73 0,000 0,39000625 0,39896048 ! transition metal ion transport GO:0000041 126 74 0,000 0,39412783 0,40300534 ! exocytosis GO:0006887 133 74 0,000 0,39412783 0,40283414 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,39412783 0,40266309 ! organelle localization GO:0051640 136 74 0,000 0,39412783 0,40249218 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,3982217 0,40650039 ! rhythmic process GO:0048511 128 75 0,000 0,3982217 0,40632799 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,40228804 0,41030311 ! defense response to bacterium GO:0042742 89 76 0,000 0,40228804 0,41012925 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,40228804 0,40995554 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,40632704 0,41389621 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,40632704 0,41372106 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,40632704 0,41354605 ! blood coagulation GO:0007596 146 78 0,000 0,41033888 0,41745257 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,41033888 0,41727614 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,41432374 0,42115036 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,41432374 0,42097251 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,41432374 0,42079481 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,41432374 0,42061726 ! inorganic anion transport GO:0015698 138 80 0,000 0,4182818 0,42445635 ! digestion GO:0007586 112 81 0,000 0,42221324 0,4282652 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,42221324 0,42808473 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,42221324 0,42790441 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,42611825 0,43168021 ! response to nutrient GO:0007584 125 82 0,000 0,42611825 0,43149853 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,43384964 0,43914272 ! nucleosome assembly GO:0006334 122 85 0,000 0,43767638 0,44282985 ! amine biosynthetic process GO:0009309 138 86 0,000 0,44147739 0,44648785 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,44147739 0,44630025 ! chromatin assembly GO:0031497 124 86 0,000 0,44147739 0,44611281 ! alcohol catabolic process GO:0046164 130 86 0,000 0,44147739 0,44592552 ! amine transport GO:0015837 155 86 0,000 0,44147739 0,44573839 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,44525282 0,4493617 ! cellular respiration GO:0045333 135 88 0,000 0,44900286 0,45295634 ! regulation of neurological system process GO:0031644 148 88 0,000 0,44900286 0,45276651 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,44900286 0,45257683 ! cellular defense response GO:0006968 114 89 0,000 0,45272767 0,45614019 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,45272767 0,45594926 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,45642743 0,45948301 ! sterol metabolic process GO:0016125 152 91 0,000 0,4601023 0,46298876 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,4601023 0,4627952 ! nucleosome organization GO:0034728 138 92 0,000 0,46375244 0,46627178 ! vitamin metabolic process GO:0006766 139 92 0,000 0,46375244 0,46607702 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,46737803 0,46952465 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,46737803 0,46932869 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,46737803 0,46913289 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,47097922 0,47255046 ! female pregnancy GO:0007565 164 94 0,000 0,47097922 0,47235349 ! forebrain development GO:0030900 188 95 0,000 0,47455619 0,47574258 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,47455619 0,47554443 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,47810909 0,47890527 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,47810909 0,47870598 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,48163808 0,48203877 ! response to virus GO:0009615 160 98 0,000 0,48514332 0,48534505 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,48514332 0,48514332