pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6630-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 95 45 6,000 1,905E-08 4,654E-05 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 6,000 2,234E-08 2,729E-05 ! response to UV GO:0009411 120 55 6,000 8,052E-08 6,557E-05 ! regulation of DNA metabolic process GO:0051052 188 97 7,000 2,916E-07 1,781E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 6,000 3,956E-07 1,933E-04 ! negative regulation of kinase activity GO:0033673 145 70 6,000 4,371E-07 1,78E-04 ! sex determination GO:0007530 48 24 4,000 4,742E-07 1,655E-04 ! negative regulation of phosphorylation GO:0042326 52 24 4,000 4,742E-07 1,448E-04 ! negative regulation of transferase activity GO:0051348 155 74 6,000 6,416E-07 1,742E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 4,000 7,26E-07 1,774E-04 GO:0045936|negative regulation of phosphate metabolic process, ! C21-steroid hormone biosynthetic process GO:0006700 26 16 3,000 3,239E-06 7,193E-04 ! negative regulation of DNA metabolic process GO:0051053 65 35 4,000 3,413E-06 6,948E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 6,000 4,31E-06 8,099E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 8,444E-06 1,473E-03 ! regulation of helicase activity GO:0051095 16 7 2,000 9,918E-06 1,615E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 9,918E-06 1,514E-03 ! C21-steroid hormone metabolic process GO:0008207 38 21 3,000 1,038E-05 1,491E-03 ! inactivation of MAPK activity GO:0000188 45 22 3,000 1,262E-05 1,712E-03 ! apoptotic nuclear changes GO:0030262 34 22 3,000 1,262E-05 1,622E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 1,579E-05 1,929E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 1,579E-05 1,837E-03 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 1,579E-05 1,754E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,579E-05 1,677E-03 ! response to calcium ion GO:0051592 94 49 4,000 1,859E-05 1,892E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 4,000 2,054E-05 2,007E-03 ! negative regulation of DNA replication GO:0008156 45 25 3,000 2,148E-05 2,018E-03 ! induction of positive chemotaxis GO:0050930 17 9 2,000 2,357E-05 2,133E-03 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 2,949E-05 2,573E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 3,351E-05 2,823E-03 ! motor axon guidance GO:0008045 22 10 2,000 3,351E-05 2,729E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 3,351E-05 2,641E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 3,000 3,422E-05 2,613E-03 ! regulation of DNA replication GO:0006275 105 56 4,000 3,585E-05 2,654E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 3,908E-05 2,808E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 4,585E-05 3,2E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 4,585E-05 3,111E-03 GO:0010829|negative regulation of glucose transport, ! T cell receptor signaling pathway GO:0050852 29 11 2,000 4,585E-05 3,027E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 6,083E-05 3,911E-03 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 6,083E-05 3,81E-03 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 6,083E-05 3,715E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of MAP kinase activity GO:0043407 78 34 3,000 7,513E-05 4,477E-03 ! response to X-ray GO:0010165 28 13 2,000 7,869E-05 4,577E-03 ! negative regulation of cell growth GO:0030308 142 67 4,000 8,542E-05 4,853E-03 ! negative regulation of cell size GO:0045792 144 69 4,000 9,834E-05 5,46E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 9,966E-05 5,41E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 9,966E-05 5,293E-03 ! hormone biosynthetic process GO:0042446 62 37 3,000 1,053E-04 5,475E-03 ! cell cycle checkpoint GO:0000075 145 71 4,000 1,127E-04 5,736E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 1,171E-04 5,839E-03 ! actin filament organization GO:0007015 167 72 4,000 1,205E-04 5,886E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 1,24E-04 5,938E-03 ! nucleus organization GO:0006997 73 40 3,000 1,435E-04 6,742E-03 ! protein polyubiquitination GO:0000209 41 16 2,000 1,518E-04 6,998E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 1,518E-04 6,869E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! T cell differentiation GO:0030217 93 42 3,000 1,739E-04 7,726E-03 ! signal complex assembly GO:0007172 47 17 2,000 1,835E-04 8,003E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 1,835E-04 7,863E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 1,835E-04 7,727E-03 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 2,000 1,835E-04 7,596E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 2,102E-04 8,558E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 2,356E-04 9,437E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 4,000 2,492E-04 9,819E-03 ! proximal/distal pattern formation GO:0009954 33 19 2,000 2,589E-04 0,01003852 ! negative regulation of growth GO:0045926 168 85 4,000 2,634E-04 0,01005275 ! response to insulin stimulus GO:0032868 98 47 3,000 2,701E-04 0,01015101 ! regulation of glucose import GO:0046324 30 20 2,000 3,031E-04 0,01121805 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 3,031E-04 0,01105061 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 3,175E-04 0,01140717 ! activation of caspase activity GO:0006919 95 50 3,000 3,433E-04 0,01215617 ! response to inorganic substance GO:0010035 173 90 4,000 3,435E-04 0,01198852 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 3,518E-04 0,01210655 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 3,518E-04 0,0119384 ! positive regulation of locomotion GO:0040017 44 22 2,000 4,054E-04 0,01356739 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 4,298E-04 0,01418963 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of helicase activity GO:0051096 12 5 1,000 4,332E-04 0,01411216 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 4,332E-04 0,01392648 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 4,332E-04 0,01374561 ! epithelial cell proliferation GO:0050673 9 5 1,000 4,332E-04 0,01356939 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 4,332E-04 0,01339762 ! microvillus organization GO:0032528 8 5 1,000 4,332E-04 0,01323015 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,332E-04 0,01306682 ! peptidyl-histidine phosphorylation GO:0018106 10 5 1,000 4,332E-04 0,01290747 ! protein insertion into membrane GO:0051205 17 5 1,000 4,332E-04 0,01275195 ! stem cell division GO:0017145 11 5 1,000 4,332E-04 0,01260014 GO:0048103|somatic stem cell division, ! regulation of chemotaxis GO:0050920 45 23 2,000 4,639E-04 0,0133343 ! cellular response to reactive oxygen species GO:0034614 35 23 2,000 4,639E-04 0,01317925 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 5,276E-04 0,01481612 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 5,276E-04 0,01464775 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 2,000 5,276E-04 0,01448317 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 5,276E-04 0,01432225 ! positive regulation of caspase activity GO:0043280 108 57 3,000 5,679E-04 0,0152461 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 3,000 5,679E-04 0,01508038 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 5,967E-04 0,01567334 ! regulation of behavior GO:0050795 48 25 2,000 5,967E-04 0,0155066 ! aging GO:0007568 112 58 3,000 6,068E-04 0,01560491 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 1,000 6,47E-04 0,01646522 ! regulation of retroviral genome replication GO:0045091 8 6 1,000 6,47E-04 0,01629547 ! early endosome to late endosome transport GO:0045022 16 6 1,000 6,47E-04 0,01612919 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 6,47E-04 0,01596627 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 6,47E-04 0,01580661 ! determination of adult lifespan GO:0008340 17 6 1,000 6,47E-04 0,01565011 ! cytoplasmic microtubule organization GO:0031122 18 6 1,000 6,47E-04 0,01549668 ! negative regulation of B cell activation GO:0050869 14 6 1,000 6,47E-04 0,01534622 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 6,712E-04 0,01576633 ! DNA catabolic process GO:0006308 94 60 3,000 6,903E-04 0,01606018 ! cellular response to oxidative stress GO:0034599 43 27 2,000 7,514E-04 0,01731751 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 7,514E-04 0,01715566 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 8,375E-04 0,01894353 ! negative regulation of protein modification process GO:0031400 66 28 2,000 8,375E-04 0,01876973 ! base-excision repair GO:0006284 41 28 2,000 8,375E-04 0,0185991 ! integrin-mediated signaling pathway GO:0007229 160 64 3,000 8,81E-04 0,01938936 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 8,81E-04 0,01921624 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 9,019E-04 0,01949764 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 9,019E-04 0,01932661 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 9,019E-04 0,01915855 ! negative regulation of DNA recombination GO:0045910 16 7 1,000 9,019E-04 0,01899339 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 9,019E-04 0,01883105 ! B cell lineage commitment GO:0002326 21 7 1,000 9,019E-04 0,01867147 ! T cell lineage commitment GO:0002360 16 7 1,000 9,019E-04 0,01851456 ! peptidyl-histidine modification GO:0018202 17 7 1,000 9,019E-04 0,01836028 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 9,295E-04 0,01876722 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 9,89E-04 0,01980481 ! immune response-activating signal transduction GO:0002757 58 30 2,000 1,028E-03 0,02041336 GO:0002764|immune response-regulating signal transduction, ! negative regulation of transcription regulator activity GO:0090048 57 30 2,000 1,028E-03 0,02024874 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 2,000 1,028E-03 0,02008675 ! embryonic limb morphogenesis GO:0030326 139 67 3,000 1,046E-03 0,02028846 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 126 67 3,000 1,046E-03 0,02012871 ! erythrocyte differentiation GO:0030218 62 31 2,000 1,132E-03 0,02161179 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 1,132E-03 0,02144426 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 1,132E-03 0,0212793 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 1,132E-03 0,02111687 ! cellular hormone metabolic process GO:0034754 120 69 3,000 1,168E-03 0,0216183 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 1,168E-03 0,02145575 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 1,000 1,197E-03 0,02182675 GO:0016446|somatic hypermutation of immunoglobulin genes, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,197E-03 0,02166507 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,197E-03 0,02150577 ! ER overload response GO:0006983 13 8 1,000 1,197E-03 0,02134879 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,197E-03 0,02119409 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 1,000 1,197E-03 0,02104162 ! DNA topological change GO:0006265 12 8 1,000 1,197E-03 0,02089132 ! multicellular organismal aging GO:0010259 20 8 1,000 1,197E-03 0,02074315 ! response to tumor cell GO:0002347 16 8 1,000 1,197E-03 0,02059707 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 1,197E-03 0,02045304 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 1,197E-03 0,020311 GO:0000076|DNA replication checkpoint, ! response to ionizing radiation GO:0010212 74 33 2,000 1,361E-03 0,0229316 ! leukocyte chemotaxis GO:0030595 55 33 2,000 1,361E-03 0,02277453 GO:0060326|cell chemotaxis, ! appendage morphogenesis GO:0035107 150 72 3,000 1,369E-03 0,02274624 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 151 73 3,000 1,441E-03 0,02377917 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 3,000 1,515E-03 0,02484072 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 1,515E-03 0,02467511 ! microtubule bundle formation GO:0001578 22 9 1,000 1,533E-03 0,0247946 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,533E-03 0,02463148 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 1,000 1,533E-03 0,02447049 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,533E-03 0,02431159 ! receptor clustering GO:0043113 20 9 1,000 1,533E-03 0,02415474 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,533E-03 0,0239999 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,533E-03 0,02384704 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,533E-03 0,02369611 ! regulation of transcription factor activity GO:0051090 137 75 3,000 1,592E-03 0,02446329 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 3,000 1,592E-03 0,0243104 ! cell-matrix adhesion GO:0007160 181 76 3,000 1,672E-03 0,02537035 ! lymphocyte differentiation GO:0030098 193 76 3,000 1,672E-03 0,02521375 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 1,755E-03 0,02629616 ! negative regulation of DNA binding GO:0043392 67 36 2,000 1,755E-03 0,02614706 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,901E-03 0,02814409 ! regulation of microtubule-based process GO:0032886 86 37 2,000 1,901E-03 0,02797455 ! negative regulation of cell activation GO:0050866 69 37 2,000 1,901E-03 0,02780703 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,907E-03 0,02773522 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 1,907E-03 0,0275711 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 1,907E-03 0,02740892 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,907E-03 0,02724863 ! DNA ligation GO:0006266 18 10 1,000 1,907E-03 0,02709021 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 1,907E-03 0,02693362 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 1,907E-03 0,02677883 ! detection of calcium ion GO:0005513 24 10 1,000 1,907E-03 0,02662581 ! steroid biosynthetic process GO:0006694 146 79 3,000 1,928E-03 0,0267619 ! DNA integrity checkpoint GO:0031570 82 38 2,000 2,054E-03 0,02834625 ! regulation of protein stability GO:0031647 77 38 2,000 2,054E-03 0,028187 ! glycogen metabolic process GO:0005977 63 38 2,000 2,054E-03 0,02802954 ! regulation of peptidase activity GO:0052547 150 82 3,000 2,21E-03 0,02999384 ! cell-substrate adhesion GO:0031589 189 82 3,000 2,21E-03 0,02982813 ! negative regulation of binding GO:0051100 71 39 2,000 2,214E-03 0,02971957 ! erythrocyte homeostasis GO:0034101 75 39 2,000 2,214E-03 0,02955717 ! glucan metabolic process GO:0044042 64 39 2,000 2,214E-03 0,02939653 GO:0006073|cellular glucan metabolic process, ! negative regulation of muscle development GO:0048635 27 11 1,000 2,321E-03 0,03064905 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,321E-03 0,03048427 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,321E-03 0,03032125 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 2,321E-03 0,03015997 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,321E-03 0,03000039 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,321E-03 0,0298425 ! DNA methylation GO:0006306 19 11 1,000 2,321E-03 0,02968625 GO:0006305|DNA alkylation, ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 1,000 2,321E-03 0,02953164 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! T cell activation GO:0042110 189 84 3,000 2,413E-03 0,03054312 ! negative regulation of transport GO:0051051 164 85 3,000 2,519E-03 0,03172244 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 2,519E-03 0,03155976 ! regulation of T cell differentiation GO:0045580 78 42 2,000 2,741E-03 0,03416284 ! mitochondrion organization GO:0007005 159 87 3,000 2,741E-03 0,03399043 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,773E-03 0,03421398 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,773E-03 0,03404205 ! focal adhesion formation GO:0048041 37 12 1,000 2,773E-03 0,03387184 ! immunoglobulin production during immune response GO:0002381 24 12 1,000 2,773E-03 0,03370332 ! histone acetylation GO:0016573 27 12 1,000 2,773E-03 0,03353647 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,773E-03 0,03337127 ! localization within membrane GO:0051668 26 12 1,000 2,773E-03 0,03320769 ! regulation of T cell proliferation GO:0042129 80 43 2,000 2,932E-03 0,03494221 ! regulation of DNA binding GO:0051101 167 89 3,000 2,976E-03 0,03529075 ! positive regulation of protein modification process GO:0031401 156 90 3,000 3,098E-03 0,0365652 ! response to reactive oxygen species GO:0000302 75 44 2,000 3,131E-03 0,03677868 ! energy reserve metabolic process GO:0006112 76 44 2,000 3,131E-03 0,0366027 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 3,131E-03 0,03642841 ! double-strand break repair GO:0006302 85 44 2,000 3,131E-03 0,03625576 ! Golgi organization GO:0007030 25 13 1,000 3,263E-03 0,03759961 ! regulation of DNA repair GO:0006282 23 13 1,000 3,263E-03 0,03742309 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,263E-03 0,03724822 ! regulation of fatty acid oxidation GO:0046320 34 13 1,000 3,263E-03 0,03707497 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 3,263E-03 0,03690333 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 3,339E-03 0,03758807 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 3,486E-03 0,03906641 ! leukocyte migration GO:0050900 75 46 2,000 3,554E-03 0,03964996 ! pigmentation GO:0043473 103 46 2,000 3,554E-03 0,03946974 ! phospholipid biosynthetic process GO:0008654 188 95 3,000 3,762E-03 0,04158839 ! regulation of S phase GO:0033261 26 14 1,000 3,79E-03 0,04170747 ! regulation of cellular pH GO:0030641 27 14 1,000 3,79E-03 0,04152045 ! response to gamma radiation GO:0010332 30 14 1,000 3,79E-03 0,04133509 ! positive regulation of cell cycle GO:0045787 96 48 2,000 4,011E-03 0,04354677 ! positive regulation of defense response GO:0031349 88 48 2,000 4,011E-03 0,04335408 ! cellular component disassembly GO:0022411 89 48 2,000 4,011E-03 0,04316309 ! regulation of inflammatory response GO:0050727 84 48 2,000 4,011E-03 0,04297378 ! leukocyte differentiation GO:0002521 232 98 3,000 4,204E-03 0,04484441 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 4,252E-03 0,04515841 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,354E-03 0,04604735 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 4,354E-03 0,04584887 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 4,354E-03 0,04565209 ! regulation of exocytosis GO:0017157 26 15 1,000 4,354E-03 0,045457 ! G1/S transition checkpoint GO:0031575 37 15 1,000 4,354E-03 0,04526357 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 4,354E-03 0,04507177 ! actin filament polymerization GO:0030041 27 15 1,000 4,354E-03 0,0448816 ! hormone metabolic process GO:0042445 171 100 3,000 4,517E-03 0,0463606 ! negative regulation of immune system process GO:0002683 101 51 2,000 4,759E-03 0,04864649 ! intermediate filament-based process GO:0045103 36 16 1,000 4,954E-03 0,05043131 ! axon cargo transport GO:0008088 46 16 1,000 4,954E-03 0,05022205 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 4,954E-03 0,05001452 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 4,954E-03 0,0498087 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,954E-03 0,04960456 ! cartilage development GO:0051216 99 53 2,000 5,302E-03 0,05286656 ! regulation of muscle contraction GO:0006937 94 54 2,000 5,587E-03 0,05547904 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 5,59E-03 0,05529375 ! endothelial cell migration GO:0043542 31 17 1,000 5,59E-03 0,0550708 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 5,59E-03 0,05484963 ! regulation of survival gene product expression GO:0045884 38 17 1,000 5,59E-03 0,05463023 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 5,59E-03 0,05441258 GO:0031114|regulation of microtubule depolymerization, ! regulation of viral genome replication GO:0045069 30 18 1,000 6,262E-03 0,06070577 ! cell-substrate junction assembly GO:0007044 56 18 1,000 6,262E-03 0,06046582 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 6,262E-03 0,06022777 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 6,262E-03 0,05999158 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 6,262E-03 0,05975724 ! positive regulation of cell migration GO:0030335 137 58 2,000 6,816E-03 0,06479317 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 6,816E-03 0,06454204 ! pigmentation during development GO:0048066 42 19 1,000 6,968E-03 0,06572663 ! neuromuscular junction development GO:0007528 43 19 1,000 6,968E-03 0,06547384 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 1,000 6,968E-03 0,06522298 ! lipid modification GO:0030258 112 60 2,000 7,486E-03 0,06980651 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 7,709E-03 0,07160608 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,709E-03 0,07133484 ! protein amino acid acetylation GO:0006473 41 20 1,000 7,709E-03 0,07106565 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 7,709E-03 0,07079849 ! forelimb morphogenesis GO:0035136 35 20 1,000 7,709E-03 0,07053333 ! response to alkaloid GO:0043279 38 20 1,000 7,709E-03 0,07027014 ! cellular response to unfolded protein GO:0034620 35 20 1,000 7,709E-03 0,07000892 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 1,000 7,709E-03 0,06974962 ! fatty acid beta-oxidation GO:0006635 36 20 1,000 7,709E-03 0,06949225 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 7,709E-03 0,06923676 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 7,709E-03 0,06898314 ! regulation of heart contraction GO:0008016 123 61 2,000 7,836E-03 0,06986292 ! camera-type eye development GO:0043010 126 61 2,000 7,836E-03 0,06960887 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 7,836E-03 0,06935667 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 8,194E-03 0,07226969 ! lipid phosphorylation GO:0046834 43 21 1,000 8,483E-03 0,07454775 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 8,483E-03 0,07428056 ! prostaglandin metabolic process GO:0006693 43 21 1,000 8,483E-03 0,07401527 GO:0006692|prostanoid metabolic process, ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 8,483E-03 0,07375187 ! skeletal system morphogenesis GO:0048705 118 63 2,000 8,563E-03 0,07417812 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 8,94E-03 0,07717721 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 1,000 9,291E-03 0,07992134 ! microtubule-based transport GO:0010970 59 22 1,000 9,291E-03 0,07964092 ! hindlimb morphogenesis GO:0035137 47 22 1,000 9,291E-03 0,07936245 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 9,291E-03 0,07908593 ! cellular response to starvation GO:0009267 37 22 1,000 9,291E-03 0,07881132 ! actin polymerization or depolymerization GO:0008154 52 22 1,000 9,291E-03 0,07853862 ! cell aging GO:0007569 48 22 1,000 9,291E-03 0,0782678 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 9,291E-03 0,07799884 ! G1 phase GO:0051318 44 22 1,000 9,291E-03 0,07773172 ! detection of chemical stimulus GO:0009593 42 22 1,000 9,291E-03 0,07746642 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 9,291E-03 0,07720293 ! positive regulation of B cell activation GO:0050871 42 22 1,000 9,291E-03 0,07694122 ! somatic diversification of immunoglobulins GO:0016445 55 22 1,000 9,291E-03 0,07668129 ! protein stabilization GO:0050821 41 22 1,000 9,291E-03 0,0764231 ! positive regulation of cell motion GO:0051272 157 65 2,000 9,328E-03 0,0764684 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 9,725E-03 0,07945702 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 0,01013156 0,08250466 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 1,000 0,01013156 0,08223056 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 0,01013156 0,08195827 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 0,01013156 0,08168779 ! DNA modification GO:0006304 36 23 1,000 0,01013156 0,08141908 ! homeostasis of number of cells GO:0048872 131 69 2,000 0,01097451 0,08790406 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 1,000 0,01100464 0,08785733 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 0,01100464 0,08757115 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 1,000 0,01100464 0,08728683 ! regulation of viral reproduction GO:0050792 41 24 1,000 0,01100464 0,08700435 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 0,01100464 0,08672369 ! negative regulation of catabolic process GO:0009895 52 24 1,000 0,01100464 0,08644484 ! activation of immune response GO:0002253 120 70 2,000 0,01141072 0,08934743 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 0,01185681 0,09254376 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 0,01190969 0,09266039 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 0,01190969 0,09236623 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 0,01190969 0,09207394 ! vasculogenesis GO:0001570 49 25 1,000 0,01190969 0,09178348 ! receptor metabolic process GO:0043112 53 25 1,000 0,01190969 0,09149485 ! chromosome condensation GO:0030261 48 25 1,000 0,01190969 0,09120804 ! immunoglobulin production GO:0002377 62 25 1,000 0,01190969 0,09092301 GO:0002440|production of molecular mediator of immune response, ! protein tetramerization GO:0051262 57 25 1,000 0,01190969 0,09063976 ! B cell activation GO:0042113 179 72 2,000 0,01231282 0,09341683 ! myelination GO:0042552 50 26 1,000 0,01284623 0,09716203 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 0,01284623 0,09686215 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 0,01284623 0,09656411 ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 0,01284623 0,0962679 ! negative regulation of cell development GO:0010721 83 26 1,000 0,01284623 0,0959735 GO:0050768|negative regulation of neurogenesis, ! somatic diversification of immune receptors GO:0002200 63 26 1,000 0,01284623 0,0956809 ! neural tube closure GO:0001843 58 26 1,000 0,01284623 0,09539008 GO:0060606|tube closure, ! eye development GO:0001654 155 75 2,000 0,01374064 0,10172241 ! axon guidance GO:0007411 162 75 2,000 0,01374064 0,10141509 ! tube lumen formation GO:0035148 59 27 1,000 0,01381382 0,10164804 ! mitochondrial membrane organization GO:0007006 60 27 1,000 0,01381382 0,10134279 ! response to starvation GO:0042594 47 27 1,000 0,01381382 0,10103937 ! regulation of chromosome organization GO:0033044 49 27 1,000 0,01381382 0,10073776 ! cellular response to nutrient levels GO:0031669 45 27 1,000 0,01381382 0,10043795 ! learning or memory GO:0007611 161 76 2,000 0,01423662 0,10320492 ! neurotransmitter transport GO:0006836 142 77 2,000 0,01474265 0,10655707 ! protein amino acid acylation GO:0043543 59 28 1,000 0,014812 0,1067425 ! dendrite development GO:0016358 67 28 1,000 0,014812 0,10642855 ! fat cell differentiation GO:0045444 57 28 1,000 0,014812 0,10611645 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 0,014812 0,10580616 ! glutathione metabolic process GO:0006749 42 28 1,000 0,014812 0,10549769 ! lipid oxidation GO:0034440 48 28 1,000 0,014812 0,10519101 GO:0019395|fatty acid oxidation, ! protein oligomerization GO:0051259 149 79 2,000 0,01578498 0,11177593 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01584033 0,1118437 ! primary neural tube formation GO:0014020 61 29 1,000 0,01584033 0,11152139 ! somitogenesis GO:0001756 52 29 1,000 0,01584033 0,11120092 ! neurotransmitter secretion GO:0007269 55 30 1,000 0,01689837 0,11828857 ! cell junction assembly GO:0034329 85 31 1,000 0,01798568 0,12554004 ! male gonad development GO:0008584 56 31 1,000 0,01798568 0,12518238 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01798568 0,12482675 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01798568 0,12447313 GO:0008366|axon ensheathment, ! fatty acid catabolic process GO:0009062 54 31 1,000 0,01798568 0,12412151 ! response to heat GO:0009408 54 31 1,000 0,01798568 0,12377187 ! response to drug GO:0042493 149 83 2,000 0,01799121 0,12346212 ! metanephros development GO:0001656 81 32 1,000 0,01910183 0,13071646 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01910183 0,13035133 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01910183 0,12998824 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01910183 0,12962716 ! regulation of pH GO:0006885 56 33 1,000 0,0202464 0,13701371 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,0202464 0,13663522 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,0202464 0,13625882 ! response to unfolded protein GO:0006986 139 90 2,000 0,02224422 0,14929292 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,02224422 0,1488839 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,02261908 0,15097927 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,02261908 0,15056788 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,02261908 0,15015873 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,02355126 0,15592338 ! regulation of muscle development GO:0048634 82 36 1,000 0,02384636 0,15745045 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,02384636 0,15702605 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,02510039 0,16483941 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,02510039 0,16439748 ! cell junction organization GO:0034330 96 37 1,000 0,02510039 0,16395791 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,02510039 0,16352069 ! regulation of defense response GO:0031347 171 95 2,000 0,02558839 0,16625651 ! response to protein stimulus GO:0051789 158 96 2,000 0,02628784 0,17034798 ! regulation of T cell activation GO:0050863 175 96 2,000 0,02628784 0,16989732 ! meiosis I GO:0007127 74 38 1,000 0,02638076 0,17004803 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,02638076 0,16960053 ! neural tube formation GO:0001841 79 38 1,000 0,02638076 0,16915539 ! transcription initiation GO:0006352 171 97 2,000 0,02699747 0,17265658 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,02768707 0,17660447 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,02768707 0,17614456 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 0,02901892 0,18413823 ! learning GO:0007612 82 40 1,000 0,02901892 0,18366119 ! mismatch repair GO:0006298 58 40 1,000 0,02901892 0,18318661 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,02901892 0,18271448 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,02918737 0,1833027 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 2,000 0,02918737 0,1828327 ! feeding behavior GO:0007631 69 41 1,000 0,03037591 0,1897912 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,03037591 0,18930703 ! maintenance of protein location GO:0045185 95 41 1,000 0,03037591 0,18882534 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,03037591 0,18834609 ! ear morphogenesis GO:0042471 64 42 1,000 0,03175767 0,19641514 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,03175767 0,19591914 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03276218 0,20160704 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03276218 0,20110049 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,03276218 0,20059648 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03276218 0,20009499 ! neuron fate determination GO:0048664 7 5 0,000 0,03276218 0,199596 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03276218 0,19909949 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03276218 0,19860544 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,03276218 0,19811385 ! polyol transport GO:0015791 12 5 0,000 0,03276218 0,19762468 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03276218 0,19713792 ! response to superoxide GO:0000303 10 5 0,000 0,03276218 0,19665355 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03276218 0,19617155 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03276218 0,19569192 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03276218 0,19521462 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03276218 0,19473965 ! female meiosis GO:0007143 10 5 0,000 0,03276218 0,19426698 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,03276218 0,1937966 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03276218 0,19332849 ! hypothalamus development GO:0021854 9 5 0,000 0,03276218 0,19286264 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03276218 0,19239902 ! cobalt ion transport GO:0006824 11 5 0,000 0,03276218 0,19193764 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03276218 0,19147846 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03276218 0,19102147 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03276218 0,19056665 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03276218 0,190114 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03276218 0,18966349 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,03276218 0,18921512 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03276218 0,18876885 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03276218 0,18832469 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,03276218 0,18788262 ! transposition GO:0032196 9 5 0,000 0,03276218 0,18744261 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,03276218 0,18700466 ! negative chemotaxis GO:0050919 16 5 0,000 0,03276218 0,18656875 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03276218 0,18613487 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03276218 0,185703 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03276218 0,18527313 ! behavioral response to pain GO:0048266 10 5 0,000 0,03276218 0,18484525 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03276218 0,18441934 ! Notch receptor processing GO:0007220 11 5 0,000 0,03276218 0,18399539 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03276218 0,18357338 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,03276218 0,1831533 ! micturition GO:0060073 9 5 0,000 0,03276218 0,18273515 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03276218 0,18231889 ! copulation GO:0007620 9 5 0,000 0,03276218 0,18190453 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03276218 0,18149205 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03276218 0,18108144 ! bioluminescence GO:0008218 9 5 0,000 0,03276218 0,18067267 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03276218 0,18026575 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03276218 0,17986066 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03276218 0,17945739 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,03276218 0,17905592 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03276218 0,17865624 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03276218 0,17825834 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03276218 0,17786221 ! grooming behavior GO:0007625 6 5 0,000 0,03276218 0,17746784 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03276218 0,17707521 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03276218 0,17668431 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03276218 0,17629514 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03276218 0,17590768 ! response to protozoan GO:0001562 13 5 0,000 0,03276218 0,17552192 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,03276218 0,17513784 ! lymph vessel development GO:0001945 10 5 0,000 0,03276218 0,17475545 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,03276218 0,17437472 ! endochondral ossification GO:0001958 17 5 0,000 0,03276218 0,17399564 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03276218 0,17361821 ! single strand break repair GO:0000012 8 5 0,000 0,03276218 0,17324241 ! parathyroid gland development GO:0060017 14 5 0,000 0,03276218 0,17286824 ! anagen GO:0042640 7 5 0,000 0,03276218 0,17249568 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03276218 0,17212472 ! cytokine secretion GO:0050663 15 5 0,000 0,03276218 0,17175535 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03276218 0,17138757 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03276218 0,17102136 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,03276218 0,1706567 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,03276218 0,1702936 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03276218 0,16993205 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03276218 0,16957202 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,03276218 0,16921352 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03276218 0,16885653 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03276218 0,16850104 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,03276218 0,16814705 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03276218 0,16779454 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03276218 0,1674435 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03276218 0,16709393 ! valine metabolic process GO:0006573 12 5 0,000 0,03276218 0,16674582 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03276218 0,16639916 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,03276218 0,16605393 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03276218 0,16571013 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03276218 0,16536776 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03276218 0,16502679 ! polyol catabolic process GO:0046174 9 5 0,000 0,03276218 0,16468723 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03276218 0,16434906 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03276218 0,16401228 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03276218 0,16367688 ! muscle cell migration GO:0014812 8 5 0,000 0,03276218 0,16334285 ! mitochondrial fission GO:0000266 8 5 0,000 0,03276218 0,16301017 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,03276218 0,16267885 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03276218 0,16234887 ! mRNA transcription GO:0009299 10 5 0,000 0,03276218 0,16202023 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03276218 0,16169292 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03276218 0,16136692 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03276218 0,16104224 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03276218 0,16071886 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03276218 0,16039678 ! monocyte activation GO:0042117 10 5 0,000 0,03276218 0,16007599 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03276218 0,15975648 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03276218 0,15943824 ! response to food GO:0032094 6 5 0,000 0,03276218 0,15912126 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03276218 0,15880554 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03276218 0,15849108 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,03276218 0,15817785 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03276218 0,15786587 ! forebrain neuron development GO:0021884 13 5 0,000 0,03276218 0,15755511 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03276218 0,15724557 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,03276218 0,15693724 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03276218 0,15663013 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03276218 0,15632421 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03276218 0,15601948 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03276218 0,15571594 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03276218 0,15541358 ! lipid glycosylation GO:0030259 7 5 0,000 0,03276218 0,15511239 ! nucleobase transport GO:0015851 6 5 0,000 0,03276218 0,15481237 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03276218 0,1545135 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03276218 0,15421579 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03276218 0,15391922 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03276218 0,15362379 ! basic amino acid transport GO:0015802 12 5 0,000 0,03276218 0,15332949 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03276218 0,15303632 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03276218 0,15274426 ! actin nucleation GO:0045010 11 5 0,000 0,03276218 0,15245332 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03276218 0,15216349 ! depurination GO:0045007 5 5 0,000 0,03276218 0,15187475 ! depyrimidination GO:0045008 10 5 0,000 0,03276218 0,15158711 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03276218 0,15130056 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03276218 0,15101508 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03276218 0,15073069 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03276218 0,15044736 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03276218 0,15016509 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,03276218 0,14988388 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03276218 0,14960373 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03276218 0,14932462 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03276218 0,14904654 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03276218 0,14876951 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03276218 0,1484935 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03276218 0,14821851 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03276218 0,14794454 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03276218 0,14767158 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03276218 0,14739962 ! response to arsenic GO:0046685 11 5 0,000 0,03276218 0,14712867 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,03276218 0,14685871 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03276218 0,14658973 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03276218 0,14632174 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03276218 0,14605473 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,03276218 0,1457887 ! response to mercury ion GO:0046689 8 5 0,000 0,03276218 0,14552363 ! response to cadmium ion GO:0046686 7 5 0,000 0,03276218 0,14525952 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03276218 0,14499637 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03276218 0,14473417 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03276218 0,14447291 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03276218 0,1442126 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03276218 0,14395323 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03276218 0,14369478 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03276218 0,14343727 ! decidualization GO:0046697 11 5 0,000 0,03276218 0,14318067 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03276218 0,14292499 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03276218 0,14267022 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03276218 0,14241636 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,03276218 0,1421634 ! embryonic cleavage GO:0040016 6 5 0,000 0,03276218 0,14191134 ! peroxisome fission GO:0016559 5 5 0,000 0,03276218 0,14166017 ! histone demethylation GO:0016577 13 5 0,000 0,03276218 0,14140988 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03276218 0,14116048 ! mitotic recombination GO:0006312 9 5 0,000 0,03276218 0,14091196 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03276218 0,14066431 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03276218 0,14041753 ! metaphase plate congression GO:0051310 7 5 0,000 0,03276218 0,14017162 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03276218 0,13992656 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03276218 0,13968236 ! enteric nervous system development GO:0048484 8 5 0,000 0,03276218 0,13943901 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,03276218 0,13919651 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03276218 0,13895485 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03276218 0,13871403 ! muscle cell proliferation GO:0033002 12 5 0,000 0,03276218 0,13847404 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03276218 0,13823488 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,03276218 0,13799654 ! B cell homeostasis GO:0001782 13 5 0,000 0,03276218 0,13775903 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,03276218 0,13752233 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03276218 0,13728644 ! metaphase GO:0051323 11 5 0,000 0,03276218 0,13705136 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03276218 0,13681708 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03276218 0,13658361 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03276218 0,13635093 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03276218 0,13611904 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03276218 0,13588794 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03276218 0,13565762 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03276218 0,13542808 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,03276218 0,13519931 ! response to redox state GO:0051775 6 5 0,000 0,03276218 0,13497132 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,03276218 0,1347441 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03276218 0,13451764 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03276218 0,13429194 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03276218 0,13406699 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03276218 0,1338428 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03276218 0,13361936 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03276218 0,13339666 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03276218 0,1331747 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,03276218 0,13295348 ! striatum development GO:0021756 14 5 0,000 0,03276218 0,13273299 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03276218 0,13251324 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03276218 0,13229421 ! glial cell migration GO:0008347 10 5 0,000 0,03276218 0,1320759 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03276218 0,13185831 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03276218 0,13164144 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,03276218 0,13142528 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03276218 0,13120983 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03276218 0,13099508 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03276218 0,13078104 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03276218 0,13056769 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03276218 0,13035504 ! neuroprotection GO:0043526 8 5 0,000 0,03276218 0,13014308 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03276218 0,12993181 ! regulation of sensory perception GO:0051931 8 5 0,000 0,03276218 0,12972122 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03276218 0,12951132 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03276218 0,12930209 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03276218 0,12909354 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03276218 0,12888566 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03276218 0,12867845 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03276218 0,1284719 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03276218 0,12826602 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03276218 0,12806079 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03276218 0,12785622 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03276218 0,1276523 ! spindle assembly GO:0051225 6 5 0,000 0,03276218 0,12744904 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03276218 0,12724641 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03276218 0,12704444 ! protein palmitoylation GO:0018345 12 5 0,000 0,03276218 0,1268431 ! drug metabolic process GO:0017144 7 5 0,000 0,03276218 0,1266424 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03276218 0,12644233 ! organ regeneration GO:0031100 7 5 0,000 0,03276218 0,12624289 ! carnitine metabolic process GO:0009437 8 5 0,000 0,03276218 0,12604409 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03276218 0,1258459 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,03316379 0,12718861 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,03316379 0,12698925 ! glucose transport GO:0015758 66 43 1,000 0,03316379 0,12679052 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,03316379 0,12659241 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,03316379 0,12639492 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,03316379 0,12619804 ! segmentation GO:0035282 78 43 1,000 0,03316379 0,12600178 ! neuron migration GO:0001764 85 43 1,000 0,03316379 0,12580612 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,03316379 0,12561107 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,03459391 0,13082494 ! hexose transport GO:0008645 68 44 1,000 0,03459391 0,13062274 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 91 45 1,000 0,03604763 0,1359018 ! B cell differentiation GO:0030183 124 45 1,000 0,03604763 0,1356924 ! maintenance of location in cell GO:0051651 101 45 1,000 0,03604763 0,13548364 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,0375246 0,14081812 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,0375246 0,14060214 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,0375246 0,14038682 ! neural tube development GO:0021915 91 47 1,000 0,03902443 0,14577476 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03918521 0,14615185 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03918521 0,14592906 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03918521 0,14570694 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03918521 0,1454855 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03918521 0,14526474 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03918521 0,14504464 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03918521 0,14482521 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03918521 0,14460644 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03918521 0,14438833 ! response to oxygen radical GO:0000305 11 6 0,000 0,03918521 0,14417087 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03918521 0,14395408 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03918521 0,14373793 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03918521 0,14352243 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03918521 0,14330758 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03918521 0,14309336 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03918521 0,14287979 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03918521 0,14266686 ! forebrain regionalization GO:0021871 9 6 0,000 0,03918521 0,14245455 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03918521 0,14224288 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03918521 0,14203184 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03918521 0,14182142 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03918521 0,14161163 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03918521 0,14140245 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03918521 0,1411939 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03918521 0,14098595 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03918521 0,14077862 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03918521 0,1405719 ! malate metabolic process GO:0006108 13 6 0,000 0,03918521 0,14036578 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03918521 0,14016026 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03918521 0,13995535 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03918521 0,13975104 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03918521 0,13954732 ! protein refolding GO:0042026 15 6 0,000 0,03918521 0,13934419 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03918521 0,13914166 ! opsonization GO:0008228 8 6 0,000 0,03918521 0,13893971 ! mating behavior GO:0007617 7 6 0,000 0,03918521 0,13873835 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03918521 0,13853757 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03918521 0,13833737 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03918521 0,13813775 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03918521 0,1379387 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03918521 0,13774023 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03918521 0,13754233 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03918521 0,13734499 ! toxin metabolic process GO:0009404 11 6 0,000 0,03918521 0,13714822 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03918521 0,13695202 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03918521 0,13675637 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03918521 0,13656129 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03918521 0,13636675 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03918521 0,13617278 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03918521 0,13597935 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03918521 0,13578647 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03918521 0,13559414 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03918521 0,13540235 ! thymic T cell selection GO:0045061 16 6 0,000 0,03918521 0,1352111 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03918521 0,1350204 ! protein lipoylation GO:0009249 10 6 0,000 0,03918521 0,13483023 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03918521 0,13464059 GO:0070633|transepithelial transport, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03918521 0,13445149 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03918521 0,13426292 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03918521 0,13407488 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03918521 0,13388736 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03918521 0,13370036 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03918521 0,13351389 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03918521 0,13332794 ! hyperosmotic response GO:0006972 10 6 0,000 0,03918521 0,1331425 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03918521 0,13295758 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03918521 0,13277318 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03918521 0,13258928 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03918521 0,13240589 ! urea metabolic process GO:0019627 7 6 0,000 0,03918521 0,13222301 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03918521 0,13204064 ! neutrophil activation GO:0042119 7 6 0,000 0,03918521 0,13185876 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03918521 0,13167739 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03918521 0,13149651 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03918521 0,13131613 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03918521 0,13113625 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03918521 0,13095685 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03918521 0,13077795 ! neuron apoptosis GO:0051402 15 6 0,000 0,03918521 0,13059954 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03918521 0,13042161 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03918521 0,13024416 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03918521 0,1300672 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03918521 0,12989072 ! carnitine transport GO:0015879 10 6 0,000 0,03918521 0,12971472 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03918521 0,12953919 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03918521 0,12936414 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03918521 0,12918956 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03918521 0,12901545 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03918521 0,1288418 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03918521 0,12866863 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03918521 0,12849592 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03918521 0,12832367 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03918521 0,12815189 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03918521 0,12798056 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03918521 0,12780969 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03918521 0,12763928 ! response to UV-C GO:0010225 14 6 0,000 0,03918521 0,12746932 ! astrocyte development GO:0014002 16 6 0,000 0,03918521 0,12729982 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03918521 0,12713076 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03918521 0,12696215 ! interaction with symbiont GO:0051702 14 6 0,000 0,03918521 0,12679399 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03918521 0,12662627 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03918521 0,126459 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03918521 0,12629216 ! response to copper ion GO:0046688 10 6 0,000 0,03918521 0,12612577 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03918521 0,12595982 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03918521 0,1257943 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03918521 0,12562921 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03918521 0,12546456 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03918521 0,12530034 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03918521 0,12513655 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03918521 0,12497319 ! hair follicle maturation GO:0048820 8 6 0,000 0,03918521 0,12481025 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03918521 0,12464774 ! Schwann cell development GO:0014044 15 6 0,000 0,03918521 0,12448564 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03918521 0,12432398 ! response to pheromone GO:0019236 6 6 0,000 0,03918521 0,12416272 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03918521 0,12400189 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03918521 0,12384148 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03918521 0,12368147 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03918521 0,12352189 ! subpallium development GO:0021544 15 6 0,000 0,03918521 0,12336271 ! neural tube patterning GO:0021532 8 6 0,000 0,03918521 0,12320394 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03918521 0,12304558 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03918521 0,12288763 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03918521 0,12273008 ! G2 phase GO:0051319 16 6 0,000 0,03918521 0,12257293 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03918521 0,12241619 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03918521 0,12225985 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03918521 0,1221039 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03918521 0,12194836 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03918521 0,12179321 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03918521 0,12163845 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03918521 0,12148409 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03918521 0,12133012 ! receptor internalization GO:0031623 11 6 0,000 0,03918521 0,12117653 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03918521 0,12102334 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03918521 0,12087053 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03918521 0,12071811 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03918521 0,12056607 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03918521 0,12041442 ! protein deubiquitination GO:0016579 16 6 0,000 0,03918521 0,12026314 ! protein destabilization GO:0031648 9 6 0,000 0,03918521 0,12011225 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03918521 0,11996173 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03918521 0,11981159 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03918521 0,11966183 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03918521 0,11951244 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03918521 0,11936342 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03918521 0,11921477 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03918521 0,11906649 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03918521 0,11891859 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03918521 0,11877104 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03918521 0,11862387 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03918521 0,11847706 ! neural plate development GO:0001840 9 6 0,000 0,03918521 0,11833061 ! catecholamine transport GO:0051937 9 6 0,000 0,03918521 0,11818452 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03918521 0,11803879 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03918521 0,11789342 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03918521 0,11774841 ! maternal placenta development GO:0001893 12 6 0,000 0,03918521 0,11760376 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03918521 0,11745946 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03918521 0,11731552 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03918521 0,11717192 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03918521 0,11702868 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03918521 0,11688579 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03918521 0,11674325 GO:0055081|anion homeostasis, ! mitochondrial transport GO:0006839 94 48 1,000 0,04054677 0,12065258 ! endosome transport GO:0016197 127 48 1,000 0,04054677 0,1205058 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,04054677 0,12035938 ! male sex differentiation GO:0046661 93 48 1,000 0,04054677 0,12021331 ! icosanoid metabolic process GO:0006690 92 48 1,000 0,04054677 0,1200676 ! methylation GO:0032259 97 48 1,000 0,04054677 0,11992224 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,04209125 0,1243397 ! protein homooligomerization GO:0051260 84 49 1,000 0,04209125 0,12418953 ! regulation of action potential GO:0001508 102 50 1,000 0,04365751 0,12865538 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,04365751 0,12850037 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,04365751 0,12834574 ! peptide metabolic process GO:0006518 80 51 1,000 0,0452452 0,13285341 ! response to temperature stimulus GO:0009266 84 51 1,000 0,0452452 0,13269392 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,0452452 0,13253481 ! tRNA transcription GO:0009304 17 7 0,000 0,04556577 0,13331397 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04556577 0,1331545 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04556577 0,13299542 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04556577 0,13283671 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,04556577 0,13267839 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04556577 0,13252044 ! sleep GO:0030431 16 7 0,000 0,04556577 0,13236286 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04556577 0,13220566 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04556577 0,13204883 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04556577 0,13189238 ! prostate gland development GO:0030850 14 7 0,000 0,04556577 0,13173629 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04556577 0,13158057 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04556577 0,13142522 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04556577 0,13127024 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04556577 0,13111562 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04556577 0,13096137 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04556577 0,13080748 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04556577 0,13065395 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04556577 0,13050078 ! glycolipid transport GO:0046836 11 7 0,000 0,04556577 0,13034797 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04556577 0,13019552 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04556577 0,13004342 ! neuron adhesion GO:0007158 14 7 0,000 0,04556577 0,12989168 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04556577 0,12974029 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04556577 0,12958925 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,04556577 0,12943856 ! mRNA stabilization GO:0048255 18 7 0,000 0,04556577 0,12928823 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,04556577 0,12913824 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,04556577 0,1289886 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,04556577 0,12883931 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,04556577 0,12869036 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04556577 0,12854176 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04556577 0,1283935 ! lipoprotein transport GO:0042953 14 7 0,000 0,04556577 0,12824558 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04556577 0,128098 ! rhythmic behavior GO:0007622 17 7 0,000 0,04556577 0,12795077 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04556577 0,12780386 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,04556577 0,1276573 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04556577 0,12751107 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,04556577 0,12736518 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04556577 0,12721962 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,04556577 0,12707439 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04556577 0,12692949 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,04556577 0,12678493 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04556577 0,12664069 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,04556577 0,12649678 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04556577 0,1263532 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,04556577 0,12620994 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04556577 0,12606701 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04556577 0,1259244 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04556577 0,12578211 ! spinal cord patterning GO:0021511 14 7 0,000 0,04556577 0,12564014 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04556577 0,1254985 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04556577 0,12535717 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04556577 0,12521616 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,04556577 0,12507547 ! adrenal gland development GO:0030325 17 7 0,000 0,04556577 0,12493509 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04556577 0,12479503 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04556577 0,12465528 ! ovulation GO:0030728 10 7 0,000 0,04556577 0,12451585 ! adenohypophysis development GO:0021984 11 7 0,000 0,04556577 0,12437672 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,04556577 0,12423791 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,04556577 0,1240994 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,04556577 0,12396121 ! microtubule nucleation GO:0007020 21 7 0,000 0,04556577 0,12382332 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04556577 0,12368574 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,04556577 0,12354846 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04556577 0,12341149 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04556577 0,12327482 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04556577 0,12313846 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04556577 0,12300239 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04556577 0,12286663 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04556577 0,12273116 ! galactose metabolic process GO:0006012 13 7 0,000 0,04556577 0,122596 ! vesicle fusion GO:0006906 20 7 0,000 0,04556577 0,12246113 ! response to dietary excess GO:0002021 8 7 0,000 0,04556577 0,12232656 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04556577 0,12219228 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04556577 0,1220583 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04556577 0,12192461 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,04556577 0,12179121 ! organ growth GO:0035265 15 7 0,000 0,04556577 0,1216581 ! nucleoside transport GO:0015858 11 7 0,000 0,04556577 0,12152529 ! nucleoside salvage GO:0043174 11 7 0,000 0,04556577 0,12139277 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04556577 0,12126053 ! male sex determination GO:0030238 15 7 0,000 0,04556577 0,12112858 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04556577 0,12099692 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! parturition GO:0007567 16 7 0,000 0,04556577 0,12086554 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,04556577 0,12073445 ! rRNA modification GO:0000154 14 7 0,000 0,04556577 0,12060365 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04556577 0,12047312 ! spindle checkpoint GO:0031577 16 7 0,000 0,04556577 0,12034288 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,04556577 0,12021292 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04556577 0,12008324 ! monocyte differentiation GO:0030224 16 7 0,000 0,04556577 0,11995384 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04556577 0,11982472 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04556577 0,11969588 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,04556577 0,11956731 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04556577 0,11943902 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04556577 0,119311 ! fibrinolysis GO:0042730 11 7 0,000 0,04556577 0,11918326 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04556577 0,11905579 ! eating behavior GO:0042755 8 7 0,000 0,04556577 0,1189286 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04556577 0,11880167 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04556577 0,11867502 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04556577 0,11854863 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04556577 0,11842252 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,04556577 0,11829667 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04556577 0,11817109 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,04556577 0,11804577 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,04556577 0,11792073 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,04556577 0,11779594 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04556577 0,11767142 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04556577 0,11754717 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04556577 0,11742317 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04556577 0,11729944 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04556577 0,11717596 ! histone ubiquitination GO:0016574 9 7 0,000 0,04556577 0,11705275 ! regulation of meiosis GO:0040020 12 7 0,000 0,04556577 0,1169298 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,04556577 0,1168071 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04556577 0,11668466 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04556577 0,11656248 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04556577 0,11644055 ! transcription termination GO:0006353 14 7 0,000 0,04556577 0,11631888 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04556577 0,11619746 ! anaphase GO:0051322 18 7 0,000 0,04556577 0,11607629 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 19 7 0,000 0,04556577 0,11595538 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,04556577 0,11583472 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,04556577 0,11571431 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04556577 0,11559415 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,04556577 0,11547424 ! diuresis GO:0030146 12 7 0,000 0,04556577 0,11535458 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04556577 0,11523516 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04556577 0,11511599 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04556577 0,11499707 ! antibiotic transport GO:0042891 9 7 0,000 0,04556577 0,1148784 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04556577 0,11475996 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04556577 0,11464178 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,04556577 0,11452383 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04556577 0,11440613 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04556577 0,11428867 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04556577 0,11417145 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,04556577 0,11405447 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04556577 0,11393773 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04556577 0,11382123 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04556577 0,11370497 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04556577 0,11358894 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,04556577 0,11347316 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04556577 0,1133576 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04556577 0,11324228 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04556577 0,1131272 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04556577 0,11301235 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04556577 0,11289773 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04556577 0,11278335 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04556577 0,1126692 ! muscle adaptation GO:0043500 13 7 0,000 0,04556577 0,11255527 ! embryonic heart tube development GO:0035050 14 7 0,000 0,04556577 0,11244158 ! retina homeostasis GO:0001895 12 7 0,000 0,04556577 0,11232812 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04556577 0,11221488 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04556577 0,11210188 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,04556577 0,1119891 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,04556577 0,11187655 ! positive regulation of binding GO:0051099 88 52 1,000 0,04685397 0,11492395 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,04685397 0,11480868 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,04685397 0,11469364 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 0,04685397 0,11457883 ! histone modification GO:0016570 104 52 1,000 0,04685397 0,11446425 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,04848347 0,11832679 ! synapse organization GO:0050808 102 53 1,000 0,04848347 0,1182087 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,05013335 0,12210945 ! regulation of translational initiation GO:0006446 87 54 1,000 0,05013335 0,12198783 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,05013335 0,12186644 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 1,000 0,05013335 0,1217453 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,05013335 0,12162441 ! covalent chromatin modification GO:0016569 115 54 1,000 0,05013335 0,12150375 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,05013335 0,12138333 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,05180328 0,12530239 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,05190413 0,12542215 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,05190413 0,12529821 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,05190413 0,12517452 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,05190413 0,12505108 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05190413 0,12492787 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05190413 0,12480491 ! male meiosis GO:0007140 9 8 0,000 0,05190413 0,12468219 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,05190413 0,12455972 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,05190413 0,12443748 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,05190413 0,12431548 ! meiotic prophase I GO:0007128 14 8 0,000 0,05190413 0,12419372 ! response to zinc ion GO:0010043 12 8 0,000 0,05190413 0,1240722 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05190413 0,12395092 ! oligopeptide transport GO:0006857 16 8 0,000 0,05190413 0,12382987 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,05190413 0,12370906 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,05190413 0,12358849 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,05190413 0,12346815 ! signal peptide processing GO:0006465 12 8 0,000 0,05190413 0,12334805 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,05190413 0,12322817 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,05190413 0,12310854 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05190413 0,12298913 ! succinate metabolic process GO:0006105 17 8 0,000 0,05190413 0,12286995 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,05190413 0,12275101 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,05190413 0,12263229 ! estrogen metabolic process GO:0008210 17 8 0,000 0,05190413 0,12251381 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,05190413 0,12239555 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,05190413 0,12227752 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,05190413 0,12215972 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05190413 0,12204215 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05190413 0,1219248 ! reflex GO:0060004 17 8 0,000 0,05190413 0,12180768 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05190413 0,12169078 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,05190413 0,1215741 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,05190413 0,12145765 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05190413 0,12134143 ! pigment granule organization GO:0048753 17 8 0,000 0,05190413 0,12122542 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,05190413 0,12110964 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,05190413 0,12099408 ! astrocyte differentiation GO:0048708 19 8 0,000 0,05190413 0,12087873 ! histidine catabolic process GO:0006548 10 8 0,000 0,05190413 0,12076361 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05190413 0,12064871 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,05190413 0,12053402 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,05190413 0,12041956 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,05190413 0,1203053 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,05190413 0,12019127 ! melanin metabolic process GO:0006582 17 8 0,000 0,05190413 0,12007745 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,05190413 0,11996385 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,05190413 0,11985046 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,05190413 0,11973729 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,05190413 0,11962433 ! macrophage activation GO:0042116 13 8 0,000 0,05190413 0,11951158 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05190413 0,11939905 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,05190413 0,11928673 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,05190413 0,11917462 ! purine salvage GO:0043101 12 8 0,000 0,05190413 0,11906271 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,05190413 0,11895102 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05190413 0,11883954 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,05190413 0,11872827 ! osteoblast development GO:0002076 17 8 0,000 0,05190413 0,1186172 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,05190413 0,11850635 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,05190413 0,1183957 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,05190413 0,11828525 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,05190413 0,11817502 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05190413 0,11806498 ! response to UV-B GO:0010224 17 8 0,000 0,05190413 0,11795515 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,05190413 0,11784553 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05190413 0,11773611 ! intermediate filament organization GO:0045109 12 8 0,000 0,05190413 0,11762689 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,05190413 0,11751788 ! cellular extravasation GO:0045123 13 8 0,000 0,05190413 0,11740907 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,05190413 0,11730045 ! response to antibiotic GO:0046677 11 8 0,000 0,05190413 0,11719204 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,05190413 0,11708383 ! response to tropane GO:0014073 15 8 0,000 0,05190413 0,11697582 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,05190413 0,11686801 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,05190413 0,1167604 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05190413 0,11665298 ! mast cell activation GO:0045576 14 8 0,000 0,05190413 0,11654576 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,05190413 0,11643874 ! gas homeostasis GO:0033483 14 8 0,000 0,05190413 0,11633192 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,05190413 0,11622529 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,05190413 0,11611886 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,05190413 0,11601262 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05190413 0,11590657 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05190413 0,11580072 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,05190413 0,11569507 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05190413 0,1155896 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,05190413 0,11548433 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,05190413 0,11537925 ! intracellular lipid transport GO:0032365 16 8 0,000 0,05190413 0,11527436 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05190413 0,11516966 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,05190413 0,11506515 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,05190413 0,11496083 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,05190413 0,1148567 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05190413 0,11475275 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,05190413 0,114649 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,05190413 0,11454543 ! hormone catabolic process GO:0042447 17 8 0,000 0,05190413 0,11444205 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,05190413 0,11433886 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,05190413 0,11423585 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,05190413 0,11413303 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,05190413 0,11403039 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05190413 0,11392793 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,05190413 0,11382567 ! adult feeding behavior GO:0008343 10 8 0,000 0,05190413 0,11372358 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,05190413 0,11362168 ! ATP catabolic process GO:0006200 11 8 0,000 0,05190413 0,11351996 ! blastocyst growth GO:0001832 19 8 0,000 0,05190413 0,11341842 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05190413 0,11331706 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05190413 0,11321589 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,05190413 0,11311489 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05190413 0,11301407 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,05190413 0,11291344 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,05190413 0,11281298 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,05190413 0,1127127 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,05190413 0,1126126 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,05190413 0,11251268 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05190413 0,11241294 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,05190413 0,11231337 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,05190413 0,11221397 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05190413 0,11211476 ! protein prenylation GO:0018342 21 8 0,000 0,05190413 0,11201572 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,05190413 0,11191685 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,05190413 0,11181816 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,05190413 0,11171964 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,05190413 0,1116213 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,05349292 0,11493685 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,05349292 0,11483585 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,05349292 0,11473503 ! muscle fiber development GO:0048747 131 57 1,000 0,05520194 0,11829678 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,05520194 0,1181931 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,05520194 0,1180896 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,05693 0,12167978 ! maintenance of location GO:0051235 124 58 1,000 0,05693 0,12157342 ! axon extension GO:0048675 16 9 0,000 0,05820058 0,12417818 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05820058 0,12406982 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05820058 0,12396165 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05820058 0,12385367 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05820058 0,12374588 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05820058 0,12363828 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05820058 0,12353086 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05820058 0,12342363 ! reproductive behavior GO:0019098 22 9 0,000 0,05820058 0,12331658 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05820058 0,12320972 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05820058 0,12310305 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05820058 0,12299655 ! UTP metabolic process GO:0046051 10 9 0,000 0,05820058 0,12289025 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05820058 0,12278413 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05820058 0,12267819 ! artery development GO:0060840 25 9 0,000 0,05820058 0,12257243 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05820058 0,12246685 ! regulation of glycolysis GO:0006110 20 9 0,000 0,05820058 0,12236146 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05820058 0,12225625 ! equilibrioception GO:0050957 20 9 0,000 0,05820058 0,12215122 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05820058 0,12204637 ! chemosensory behavior GO:0007635 21 9 0,000 0,05820058 0,1219417 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05820058 0,1218372 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05820058 0,12173289 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05820058 0,12162876 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05820058 0,1215248 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05820058 0,12142102 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05820058 0,12131742 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05820058 0,121214 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05820058 0,12111075 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05820058 0,12100767 ! protein targeting to ER GO:0045047 25 9 0,000 0,05820058 0,12090478 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05820058 0,12080205 ! T cell selection GO:0045058 27 9 0,000 0,05820058 0,12069951 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05820058 0,12059713 ! glycine catabolic process GO:0006546 15 9 0,000 0,05820058 0,12049493 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05820058 0,1203929 ! endosome organization GO:0007032 20 9 0,000 0,05820058 0,12029105 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05820058 0,12018936 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05820058 0,12008785 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05820058 0,11998651 ! mannose metabolic process GO:0006013 13 9 0,000 0,05820058 0,11988534 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05820058 0,11978434 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05820058 0,11968352 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05820058 0,11958286 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05820058 0,11948237 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05820058 0,11938205 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05820058 0,11928189 ! retinol metabolic process GO:0042572 20 9 0,000 0,05820058 0,11918191 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05820058 0,11908209 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05820058 0,11898244 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05820058 0,11888296 ! macrophage differentiation GO:0030225 15 9 0,000 0,05820058 0,11878364 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05820058 0,11868449 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05820058 0,1185855 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05820058 0,11848668 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05820058 0,11838802 ! response to amine stimulus GO:0014075 13 9 0,000 0,05820058 0,11828953 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05820058 0,1181912 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05820058 0,11809304 ! erythrocyte development GO:0048821 17 9 0,000 0,05820058 0,11799504 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05820058 0,1178972 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05820058 0,11779952 ! renal water homeostasis GO:0003091 15 9 0,000 0,05820058 0,117702 ! postreplication repair GO:0006301 25 9 0,000 0,05820058 0,11760465 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05820058 0,11750745 ! icosanoid secretion GO:0032309 15 9 0,000 0,05820058 0,11741042 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05820058 0,11731355 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05820058 0,11721683 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05820058 0,11712028 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05820058 0,11702388 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05820058 0,11692765 ! sterol catabolic process GO:0016127 14 9 0,000 0,05820058 0,11683157 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05820058 0,11673565 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05820058 0,11663988 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05820058 0,11654428 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05820058 0,11644883 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05820058 0,11635353 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05820058 0,1162584 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05820058 0,11616341 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05820058 0,11606859 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05820058 0,11597391 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05820058 0,11587939 ! purine base metabolic process GO:0006144 25 9 0,000 0,05820058 0,11578503 ! pigment granule transport GO:0051904 17 9 0,000 0,05820058 0,11569082 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05820058 0,11559676 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05820058 0,11550286 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05820058 0,1154091 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05820058 0,1153155 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05820058 0,11522206 ! mitochondrion localization GO:0051646 18 9 0,000 0,05820058 0,11512876 ! nuclear export GO:0051168 110 59 1,000 0,05867679 0,11597685 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,06044197 0,11936923 ! kidney development GO:0001822 133 60 1,000 0,06044197 0,11927281 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,06222524 0,1226927 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,06402627 0,12614207 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,06445539 0,12688519 ! regulation of developmental growth GO:0048638 16 10 0,000 0,06445539 0,12678303 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,06445539 0,12668103 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06445539 0,12657919 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,06445539 0,12647752 ! associative learning GO:0008306 21 10 0,000 0,06445539 0,12637602 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06445539 0,12627467 ! phosphate transport GO:0006817 24 10 0,000 0,06445539 0,12617349 ! cell volume homeostasis GO:0006884 17 10 0,000 0,06445539 0,12607247 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,06445539 0,12597161 ! CTP metabolic process GO:0046036 11 10 0,000 0,06445539 0,12587092 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,06445539 0,12577038 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06445539 0,12567001 ! GTP metabolic process GO:0046039 11 10 0,000 0,06445539 0,12556979 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,06445539 0,12546973 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,06445539 0,12536984 ! social behavior GO:0035176 29 10 0,000 0,06445539 0,1252701 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,06445539 0,12517052 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,06445539 0,1250711 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,06445539 0,12497184 ! androgen metabolic process GO:0008209 17 10 0,000 0,06445539 0,12487273 ! phospholipid efflux GO:0033700 19 10 0,000 0,06445539 0,12477379 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06445539 0,12467499 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,06445539 0,12457636 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,06445539 0,12447788 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,06445539 0,12437956 ! lung alveolus development GO:0048286 26 10 0,000 0,06445539 0,12428139 ! pathogenesis GO:0009405 17 10 0,000 0,06445539 0,12418337 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06445539 0,12408551 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,06445539 0,12398781 ! endoderm development GO:0007492 18 10 0,000 0,06445539 0,12389026 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,06445539 0,12379286 ! arginine catabolic process GO:0006527 17 10 0,000 0,06445539 0,12369561 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06445539 0,12359852 ! proline metabolic process GO:0006560 13 10 0,000 0,06445539 0,12350158 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06445539 0,12340479 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,06445539 0,12330816 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,06445539 0,12321167 ! V(D)J recombination GO:0033151 34 10 0,000 0,06445539 0,12311534 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,06445539 0,12301915 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,06445539 0,12292312 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,06445539 0,12282724 ! B cell proliferation GO:0042100 19 10 0,000 0,06445539 0,1227315 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,06445539 0,12263592 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,06445539 0,12254048 ! multicellular organism growth GO:0035264 19 10 0,000 0,06445539 0,12244519 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,06445539 0,12235005 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,06445539 0,12225506 ! ruffle organization GO:0031529 17 10 0,000 0,06445539 0,12216022 ! epithelial cell development GO:0002064 21 10 0,000 0,06445539 0,12206552 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,06445539 0,12197097 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06445539 0,12187656 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,06445539 0,1217823 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,06445539 0,12168819 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,06445539 0,12159422 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,06445539 0,1215004 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,06445539 0,12140672 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06445539 0,12131319 ! protein heterooligomerization GO:0051291 17 10 0,000 0,06445539 0,1212198 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06445539 0,12112655 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06445539 0,12103345 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,06445539 0,12094049 ! segment specification GO:0007379 15 10 0,000 0,06445539 0,12084767 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,06445539 0,120755 ! blastoderm segmentation GO:0007350 19 10 0,000 0,06445539 0,12066247 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,06445539 0,12057007 ! response to dsRNA GO:0043331 23 10 0,000 0,06445539 0,12047783 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,06445539 0,12038572 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06445539 0,12029375 ! melanosome localization GO:0032400 16 10 0,000 0,06445539 0,12020192 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,06445539 0,12011023 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,06445539 0,12001869 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,06445539 0,11992728 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06445539 0,11983601 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,06445539 0,11974488 ! induction of an organ GO:0001759 17 10 0,000 0,06445539 0,11965389 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,06445539 0,11956304 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,06445539 0,11947232 ! protein sumoylation GO:0016925 17 10 0,000 0,06445539 0,11938174 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,06445539 0,1192913 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06445539 0,119201 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06445539 0,11911083 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,06445539 0,1190208 ! salivary gland development GO:0007431 28 10 0,000 0,06445539 0,1189309 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,06445539 0,11884115 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,06445539 0,11875152 ! midbrain development GO:0030901 14 10 0,000 0,06445539 0,11866203 ! musculoskeletal movement GO:0050881 16 10 0,000 0,06445539 0,11857268 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,06445539 0,11848346 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,06445539 0,11839437 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,06445539 0,11830542 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,06445539 0,1182166 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,06445539 0,11812792 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06445539 0,11803937 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06445539 0,11795095 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,06445539 0,11786266 GO:0043470|regulation of carbohydrate catabolic process, ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06445539 0,11777451 ! blastocyst formation GO:0001825 18 10 0,000 0,06445539 0,11768649 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,06445539 0,11759859 ! cerebellar cortex development GO:0021695 16 10 0,000 0,06445539 0,11751083 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,06445539 0,1174232 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,06445539 0,11733571 ! response to nicotine GO:0035094 20 10 0,000 0,06445539 0,11724834 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,06445539 0,1171611 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06445539 0,11707399 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,06953284 0,12620263 ! respiratory burst GO:0045730 17 11 0,000 0,07066883 0,12816924 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,07066883 0,12807416 ! neuron fate specification GO:0048665 18 11 0,000 0,07066883 0,12797922 ! telencephalon cell migration GO:0022029 23 11 0,000 0,07066883 0,12788442 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,07066883 0,12778976 ! thyroid gland development GO:0030878 26 11 0,000 0,07066883 0,12769524 ! synapsis GO:0007129 14 11 0,000 0,07066883 0,12760086 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,07066883 0,12750662 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,07066883 0,12741252 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,07066883 0,12731856 ! response to pain GO:0048265 27 11 0,000 0,07066883 0,12722473 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,07066883 0,12713105 ! blood vessel remodeling GO:0001974 30 11 0,000 0,07066883 0,1270375 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,07066883 0,12694409 ! bone resorption GO:0045453 16 11 0,000 0,07066883 0,12685082 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,07066883 0,12675768 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07066883 0,12666468 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07066883 0,12657182 ! melanocyte differentiation GO:0030318 20 11 0,000 0,07066883 0,12647909 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,07066883 0,1263865 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,07066883 0,12629405 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,07066883 0,12620173 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,07066883 0,12610954 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,07066883 0,12601749 ! UV protection GO:0009650 20 11 0,000 0,07066883 0,12592557 ! adult heart development GO:0007512 16 11 0,000 0,07066883 0,12583379 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07066883 0,12574214 ! macroautophagy GO:0016236 19 11 0,000 0,07066883 0,12565063 ! temperature homeostasis GO:0001659 18 11 0,000 0,07066883 0,12555924 ! behavioral fear response GO:0001662 27 11 0,000 0,07066883 0,125468 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,07066883 0,12537688 ! negative regulation of ossification GO:0030279 27 11 0,000 0,07066883 0,12528589 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,07066883 0,12519504 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,07066883 0,12510432 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,07066883 0,12501373 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,07066883 0,12492327 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,07066883 0,12483294 ! regulation of organ growth GO:0046620 14 11 0,000 0,07066883 0,12474275 ! pigment granule localization GO:0051875 20 11 0,000 0,07066883 0,12465268 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,07066883 0,12456274 ! vasoconstriction GO:0042310 20 11 0,000 0,07066883 0,12447294 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,07066883 0,12438326 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07066883 0,12429371 ! embryonic axis specification GO:0000578 19 11 0,000 0,07066883 0,12420429 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,07066883 0,124115 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07066883 0,12402583 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,07066883 0,1239368 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,07066883 0,12384789 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,07066883 0,12375911 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,07066883 0,12367046 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,07066883 0,12358193 ! prophase GO:0051324 17 11 0,000 0,07066883 0,12349353 ! neuroblast proliferation GO:0007405 25 11 0,000 0,07066883 0,12340526 ! nucleosome positioning GO:0016584 15 11 0,000 0,07066883 0,12331712 ! regulation of isotype switching GO:0045191 24 11 0,000 0,07066883 0,12322909 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,07066883 0,1231412 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,07066883 0,12305343 ! apical protein localization GO:0045176 18 11 0,000 0,07066883 0,12296578 ! acid secretion GO:0046717 20 11 0,000 0,07066883 0,12287826 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07066883 0,12279087 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,07066883 0,1227036 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,07066883 0,12261645 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,07066883 0,12252943 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,07066883 0,12244253 ! thymus development GO:0048538 29 11 0,000 0,07066883 0,12235575 ! cholesterol efflux GO:0033344 21 11 0,000 0,07066883 0,12226909 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07066883 0,12218256 ! oocyte development GO:0048599 20 11 0,000 0,07066883 0,12209615 ! germ cell migration GO:0008354 26 11 0,000 0,07066883 0,12200987 ! embryonic gut development GO:0048566 19 11 0,000 0,07066883 0,1219237 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,07066883 0,12183766 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,07066883 0,12175174 ! activation of innate immune response GO:0002218 16 11 0,000 0,07066883 0,12166593 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,07066883 0,12158025 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,07066883 0,1214947 ! lysogeny GO:0030069 22 11 0,000 0,07066883 0,12140926 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07066883 0,12132394 ! sequestering of metal ion GO:0051238 15 11 0,000 0,07066883 0,12123874 ! regulation of embryonic development GO:0045995 35 11 0,000 0,07066883 0,12115366 ! nucleus localization GO:0051647 22 11 0,000 0,07066883 0,1210687 ! ear development GO:0043583 114 66 1,000 0,07140185 0,12223876 ! gonad development GO:0008406 115 66 1,000 0,07140185 0,12215316 ! chromosome segregation GO:0007059 127 67 1,000 0,07328708 0,12529066 ! fatty acid biosynthetic process GO:0006633 139 67 1,000 0,07328708 0,12520304 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,07518826 0,12836124 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,07518826 0,1282716 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,07518826 0,12818209 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,07518826 0,1280927 ! regulation of lipase activity GO:0060191 137 68 1,000 0,07518826 0,12800344 ! adaptive immune response GO:0002250 126 68 1,000 0,07518826 0,1279143 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,07518826 0,12782528 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,07684119 0,13054452 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,07684119 0,1304538 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,07684119 0,13036321 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,07684119 0,13027274 ! virus-host interaction GO:0019048 30 12 0,000 0,07684119 0,1301824 ! mating GO:0007618 17 12 0,000 0,07684119 0,13009218 ! protein complex disassembly GO:0043241 28 12 0,000 0,07684119 0,13000209 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,07684119 0,12991212 ! hippocampus development GO:0021766 29 12 0,000 0,07684119 0,12982228 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,07684119 0,12973256 ! T cell proliferation GO:0042098 32 12 0,000 0,07684119 0,12964297 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07684119 0,1295535 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,07684119 0,12946415 ! ventral spinal cord development GO:0021517 25 12 0,000 0,07684119 0,12937492 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,07684119 0,12928582 ! drug transport GO:0015893 16 12 0,000 0,07684119 0,12919684 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,07684119 0,12910799 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,07684119 0,12901925 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,07684119 0,12893064 ! polyamine metabolic process GO:0006595 18 12 0,000 0,07684119 0,12884215 ! mitotic spindle organization GO:0007052 23 12 0,000 0,07684119 0,12875378 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,07684119 0,12866554 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,07684119 0,12857741 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,07684119 0,1284894 ! lipid digestion GO:0044241 21 12 0,000 0,07684119 0,12840152 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,07684119 0,12831375 ! entry into host cell GO:0030260 34 12 0,000 0,07684119 0,1282261 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07684119 0,12813858 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,07684119 0,12805117 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,07684119 0,12796388 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07684119 0,12787671 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,07684119 0,12778966 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,07684119 0,12770273 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,07684119 0,12761592 ! snRNA metabolic process GO:0016073 30 12 0,000 0,07684119 0,12752922 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,07684119 0,12744264 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,07684119 0,12735618 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07684119 0,12726984 ! cranial nerve development GO:0021545 23 12 0,000 0,07684119 0,12718361 ! fucose catabolic process GO:0019317 25 12 0,000 0,07684119 0,12709751 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 24 12 0,000 0,07684119 0,12701151 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07684119 0,12692564 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,07684119 0,12683988 ! zymogen activation GO:0031638 18 12 0,000 0,07684119 0,12675423 ! T cell homeostasis GO:0043029 28 12 0,000 0,07684119 0,1266687 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,07684119 0,12658329 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,07684119 0,12649799 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,07684119 0,12641281 ! oocyte differentiation GO:0009994 21 12 0,000 0,07684119 0,12632774 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,07684119 0,12624278 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,07684119 0,12615794 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,07684119 0,12607321 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,07684119 0,1259886 ! defense response to fungus GO:0050832 15 12 0,000 0,07684119 0,1259041 ! developmental induction GO:0031128 22 12 0,000 0,07684119 0,12581972 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,07684119 0,12573544 ! lamellipodium assembly GO:0030032 24 12 0,000 0,07684119 0,12565128 ! response to cold GO:0009409 17 12 0,000 0,07684119 0,12556723 ! establishment of cell polarity GO:0030010 21 12 0,000 0,07684119 0,1254833 ! regulation of synapse organization GO:0050807 18 12 0,000 0,07684119 0,12539948 ! lung development GO:0030324 165 69 1,000 0,07710509 0,12574616 ! urogenital system development GO:0001655 149 69 1,000 0,07710509 0,12566227 ! germ cell development GO:0007281 133 70 1,000 0,07903728 0,12872538 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,08098454 0,13180895 ! carbohydrate transport GO:0008643 114 72 1,000 0,08294659 0,13491246 ! respiratory tube development GO:0030323 171 72 1,000 0,08294659 0,1348227 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,08297271 0,13477549 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08297271 0,13468594 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,08297271 0,13459651 ! regulation of chemokine production GO:0032642 18 13 0,000 0,08297271 0,13450719 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08297271 0,134418 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,08297271 0,13432892 ! peroxisomal transport GO:0043574 28 13 0,000 0,08297271 0,13423996 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,08297271 0,13415112 ! cartilage condensation GO:0001502 22 13 0,000 0,08297271 0,13406239 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,08297271 0,13397379 ! organelle fusion GO:0048284 36 13 0,000 0,08297271 0,1338853 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,08297271 0,13379692 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,08297271 0,13370867 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,08297271 0,13362053 ! endocrine pancreas development GO:0031018 25 13 0,000 0,08297271 0,1335325 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,08297271 0,1334446 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,08297271 0,1333568 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,08297271 0,13326913 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,08297271 0,13318156 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,08297271 0,13309412 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,08297271 0,13300679 ! methionine metabolic process GO:0006555 31 13 0,000 0,08297271 0,13291957 ! plasma membrane organization GO:0007009 27 13 0,000 0,08297271 0,13283246 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,08297271 0,13274548 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,08297271 0,1326586 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,08297271 0,13257184 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,08297271 0,13248519 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,08297271 0,13239865 ! exocrine system development GO:0035272 34 13 0,000 0,08297271 0,13231223 ! asymmetric protein localization GO:0008105 24 13 0,000 0,08297271 0,13222592 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,08297271 0,13213973 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,08297271 0,13205364 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,08297271 0,13196767 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,08297271 0,13188181 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,08297271 0,13179606 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,08297271 0,13171042 ! protein homotetramerization GO:0051289 24 13 0,000 0,08297271 0,1316249 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,08297271 0,13153948 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,08297271 0,13145418 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,08297271 0,13136898 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,08297271 0,1312839 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08297271 0,13119893 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,08297271 0,13111406 ! histone methylation GO:0016571 29 13 0,000 0,08297271 0,13102931 ! chromatin silencing GO:0006342 29 13 0,000 0,08297271 0,13094466 ! gland morphogenesis GO:0022612 31 13 0,000 0,08297271 0,13086013 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,08297271 0,1307757 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,08297271 0,13069139 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08297271 0,13060718 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,08297271 0,13052308 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,08297271 0,13043909 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,08297271 0,1303552 ! spleen development GO:0048536 24 13 0,000 0,08297271 0,13027143 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,08297271 0,13018776 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,08297271 0,1301042 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,08297271 0,13002074 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,08297271 0,1299374 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,08297271 0,12985416 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08297271 0,12977102 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,08297271 0,129688 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,08297271 0,12960508 ! insulin secretion GO:0030073 24 13 0,000 0,08297271 0,12952226 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,08297271 0,12943955 ! acrosome reaction GO:0007340 19 13 0,000 0,08297271 0,12935695 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,08297271 0,12927445 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,08297271 0,12919206 ! respiratory system development GO:0060541 175 74 1,000 0,08691394 0,13524252 ! reproductive structure development GO:0048608 131 75 1,000 0,08891869 0,13827393 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,08891869 0,13818597 ! rRNA transcription GO:0009303 28 14 0,000 0,08906369 0,13832333 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,08906369 0,13823545 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,08906369 0,13814768 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,08906369 0,13806002 ! non-recombinational repair GO:0000726 29 14 0,000 0,08906369 0,13797247 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,08906369 0,13788504 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,08906369 0,13779772 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,08906369 0,1377105 ! RNA polyadenylation GO:0043631 32 14 0,000 0,08906369 0,1376234 ! lipid localization GO:0010876 32 14 0,000 0,08906369 0,13753641 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,08906369 0,13744952 ! regulated secretory pathway GO:0045055 24 14 0,000 0,08906369 0,13736275 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,08906369 0,13727608 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,08906369 0,13718953 ! arginine metabolic process GO:0006525 21 14 0,000 0,08906369 0,13710308 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,08906369 0,13701675 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,08906369 0,13693052 ! regulation of heart rate GO:0002027 25 14 0,000 0,08906369 0,1368444 ! fear response GO:0042596 34 14 0,000 0,08906369 0,13675839 ! organic alcohol transport GO:0015850 29 14 0,000 0,08906369 0,13667248 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,08906369 0,13658669 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,08906369 0,136501 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08906369 0,13641542 ! neutral amino acid transport GO:0015804 28 14 0,000 0,08906369 0,13632995 ! bone mineralization GO:0030282 18 14 0,000 0,08906369 0,13624458 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,08906369 0,13615932 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,08906369 0,13607417 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,08906369 0,13598912 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,08906369 0,13590418 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,08906369 0,13581935 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,08906369 0,13573462 ! ribosome assembly GO:0042255 18 14 0,000 0,08906369 0,13565 ! cerebellum development GO:0021549 23 14 0,000 0,08906369 0,13556548 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,08906369 0,13548107 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,08906369 0,13539676 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,08906369 0,13531256 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,08906369 0,13522846 ! NADP metabolic process GO:0006739 24 14 0,000 0,08906369 0,13514447 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,08906369 0,13506058 ! oxygen transport GO:0015671 22 14 0,000 0,08906369 0,13497679 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08906369 0,13489311 ! male genitalia development GO:0030539 26 14 0,000 0,08906369 0,13480954 ! regulation of RNA stability GO:0043487 33 14 0,000 0,08906369 0,13472606 ! regulation of axon extension GO:0030516 43 14 0,000 0,08906369 0,13464269 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,08906369 0,13455943 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,08906369 0,13447626 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,09296897 0,1402861 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,09296897 0,14019951 ! regulation of catabolic process GO:0009894 173 77 1,000 0,09296897 0,14011302 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,09501398 0,14310675 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,09511438 0,1431697 ! lactation GO:0007595 30 15 0,000 0,09511438 0,14308154 ! reproductive cellular process GO:0048610 22 15 0,000 0,09511438 0,14299349 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09511438 0,14290555 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,09511438 0,14281772 ! superoxide anion generation GO:0042554 22 15 0,000 0,09511438 0,14272999 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,09511438 0,14264237 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,09511438 0,14255486 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,09511438 0,14246746 ! copper ion transport GO:0006825 22 15 0,000 0,09511438 0,14238016 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,09511438 0,14229297 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,09511438 0,14220589 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,09511438 0,14211891 ! sulfate transport GO:0008272 27 15 0,000 0,09511438 0,14203204 ! response to cAMP GO:0051591 25 15 0,000 0,09511438 0,14194528 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,09511438 0,14185862 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,09511438 0,14177207 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,09511438 0,14168563 ! response to hexose stimulus GO:0009746 25 15 0,000 0,09511438 0,14159928 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,09511438 0,14151305 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,09511438 0,14142692 ! vesicle coating GO:0006901 38 15 0,000 0,09511438 0,14134089 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,09511438 0,14125497 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,09511438 0,14116915 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,09511438 0,14108344 ! regulation of vasodilation GO:0042312 27 15 0,000 0,09511438 0,14099783 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,09511438 0,14091233 ! histone deacetylation GO:0016575 24 15 0,000 0,09511438 0,14082692 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,09511438 0,14074163 ! water homeostasis GO:0030104 28 15 0,000 0,09511438 0,14065643 ! cofactor transport GO:0051181 30 15 0,000 0,09511438 0,14057134 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09511438 0,14048635 ! muscle maintenance GO:0046716 26 15 0,000 0,09511438 0,14040147 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,09511438 0,14031668 ! intestinal absorption GO:0050892 31 15 0,000 0,09511438 0,140232 ! dopamine metabolic process GO:0042417 35 15 0,000 0,09511438 0,14014742 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,09511438 0,14006294 ! heme biosynthetic process GO:0006783 33 15 0,000 0,09511438 0,13997857 ! cell killing GO:0001906 32 15 0,000 0,09511438 0,1398943 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,09511438 0,13981012 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,09511438 0,13972605 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,09511438 0,13964208 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,09511438 0,13955821 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,09511438 0,13947444 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,09511438 0,13939078 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,09707187 0,14217421 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,0991424 0,14511976 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,0991424 0,14503287 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,10112505 0,1478447 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,10112505 0,14775627 ! positive regulation of cell size GO:0045793 29 16 0,000 0,10112505 0,14766795 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,10112505 0,14757974 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,10112505 0,14749163 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,10112505 0,14740363 ! bone remodeling GO:0046849 28 16 0,000 0,10112505 0,14731573 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,10112505 0,14722794 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,10112505 0,14714025 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,10112505 0,14705267 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,10112505 0,14696519 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,10112505 0,14687782 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,10112505 0,14679054 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,10112505 0,14670338 ! startle response GO:0001964 28 16 0,000 0,10112505 0,14661631 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,10112505 0,14652935 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,10112505 0,14644249 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,10112505 0,14635574 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,10112505 0,14626909 ! glutamate metabolic process GO:0006536 25 16 0,000 0,10112505 0,14618254 ! pituitary gland development GO:0021983 30 16 0,000 0,10112505 0,14609609 ! response to osmotic stress GO:0006970 27 16 0,000 0,10112505 0,14600974 ! lysosomal transport GO:0007041 31 16 0,000 0,10112505 0,1459235 ! fructose metabolic process GO:0006000 25 16 0,000 0,10112505 0,14583736 ! L-amino acid transport GO:0015807 33 16 0,000 0,10112505 0,14575132 ! stem cell development GO:0048864 46 16 0,000 0,10112505 0,14566538 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10112505 0,14557954 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,10112505 0,14549381 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,10112505 0,14540817 ! negative regulation of immune response GO:0050777 38 16 0,000 0,10112505 0,14532264 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,10112505 0,14523721 ! DNA replication initiation GO:0006270 28 16 0,000 0,10112505 0,14515187 ! neuron recognition GO:0008038 40 16 0,000 0,10112505 0,14506664 ! mRNA splice site selection GO:0006376 44 16 0,000 0,10112505 0,14498151 ! tissue regeneration GO:0042246 27 16 0,000 0,10112505 0,14489647 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,10112505 0,14481154 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,10112505 0,14472671 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,10112505 0,14464197 ! biomineral formation GO:0031214 22 16 0,000 0,10112505 0,14455734 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,10112505 0,1444728 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,10112505 0,14438836 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10112505 0,14430402 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,10112505 0,14421978 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,10112505 0,14413564 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,10112505 0,1440516 ! peptide hormone processing GO:0016486 27 16 0,000 0,10112505 0,14396765 ! meiosis GO:0007126 143 81 1,000 0,1012253 0,14402645 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 1,000 0,1012253 0,14394262 ! response to hypoxia GO:0001666 178 81 1,000 0,1012253 0,14385888 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,1012253 0,14377524 ! protein import into nucleus GO:0006606 174 82 1,000 0,10332033 0,14666563 ! meiotic cell cycle GO:0051321 144 82 1,000 0,10332033 0,14658046 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,10542722 0,1494827 ! response to oxygen levels GO:0070482 183 83 1,000 0,10542722 0,14939599 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,10542722 0,14930939 ! nuclear import GO:0051170 177 83 1,000 0,10542722 0,14922288 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,10709596 0,15149706 ! metencephalon development GO:0022037 32 17 0,000 0,10709596 0,15140939 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,10709596 0,15132182 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,10709596 0,15123435 ! filopodium assembly GO:0046847 42 17 0,000 0,10709596 0,15114698 ! gene silencing by RNA GO:0031047 38 17 0,000 0,10709596 0,15105971 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,10709596 0,15097254 ! glial cell development GO:0021782 28 17 0,000 0,10709596 0,15088548 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,10709596 0,15079851 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,10709596 0,15071165 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,10709596 0,15062488 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,10709596 0,15053822 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,10709596 0,15045165 ! myoblast differentiation GO:0045445 50 17 0,000 0,10709596 0,15036518 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,10709596 0,15027882 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,10709596 0,15019255 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,10709596 0,15010638 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,10709596 0,15002031 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,10709596 0,14993434 ! NAD metabolic process GO:0019674 33 17 0,000 0,10709596 0,14984846 ! membrane budding GO:0006900 42 17 0,000 0,10709596 0,14976269 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,10709596 0,14967701 ! regulation of protein binding GO:0043393 33 17 0,000 0,10709596 0,14959143 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,10709596 0,14950595 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,10709596 0,14942057 ! genitalia development GO:0048806 32 17 0,000 0,10709596 0,14933528 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,10709596 0,1492501 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,10709596 0,14916501 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,10709596 0,14908001 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,10709596 0,14899511 ! steroid catabolic process GO:0006706 34 17 0,000 0,10709596 0,14891031 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,10709596 0,14882561 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,10709596 0,148741 ! gas transport GO:0015669 26 17 0,000 0,10709596 0,14865649 ! organic cation transport GO:0015695 32 17 0,000 0,10709596 0,14857207 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,10709596 0,14848775 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,10709596 0,14840353 ! regulation of ligase activity GO:0051340 147 84 1,000 0,10754573 0,1489423 ! hemostasis GO:0007599 165 85 1,000 0,10967562 0,15180597 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,10967562 0,15172001 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,11181664 0,15459426 ! regulation of lyase activity GO:0051339 169 86 1,000 0,11181664 0,15450682 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,11181664 0,15441948 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,11302737 0,15600331 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,11302737 0,15591523 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,11302737 0,15582724 ! limbic system development GO:0021761 40 18 0,000 0,11302737 0,15573935 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11302737 0,15565156 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,11302737 0,15556387 ! adult walking behavior GO:0007628 36 18 0,000 0,11302737 0,15547627 ! patterning of blood vessels GO:0001569 43 18 0,000 0,11302737 0,15538878 ! heart looping GO:0001947 34 18 0,000 0,11302737 0,15530139 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,11302737 0,15521409 ! centrosome cycle GO:0007098 26 18 0,000 0,11302737 0,15512689 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,11302737 0,15503979 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,11302737 0,15495279 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,11302737 0,15486588 ! glycine metabolic process GO:0006544 30 18 0,000 0,11302737 0,15477907 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11302737 0,15469236 ! response to retinoic acid GO:0032526 31 18 0,000 0,11302737 0,15460575 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,11302737 0,15451923 ! DNA integration GO:0015074 32 18 0,000 0,11302737 0,15443281 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,11302737 0,15434649 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,11302737 0,15426026 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,11302737 0,15417413 ! neural crest cell migration GO:0001755 41 18 0,000 0,11302737 0,15408809 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,11302737 0,15400216 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,11302737 0,15391631 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,11302737 0,15383057 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,11302737 0,15374491 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,11302737 0,15365936 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,11302737 0,1535739 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,11302737 0,15348853 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,11302737 0,15340326 ! detection of bacterium GO:0016045 22 18 0,000 0,11302737 0,15331808 ! nerve development GO:0021675 34 18 0,000 0,11302737 0,153233 ! defense response to virus GO:0051607 43 18 0,000 0,11302737 0,15314801 ! microspike assembly GO:0030035 46 18 0,000 0,11302737 0,15306312 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,11302737 0,15297832 ! regulation of protein transport GO:0051223 165 87 1,000 0,11396856 0,15416677 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,11613113 0,15700517 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,11830412 0,15985451 ! tube morphogenesis GO:0035239 194 89 1,000 0,11830412 0,15976615 ! protein localization in nucleus GO:0034504 192 89 1,000 0,11830412 0,15967788 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,11891955 0,16041991 ! positive regulation of translation GO:0045727 31 19 0,000 0,11891955 0,16033138 ! negative regulation of defense response GO:0031348 27 19 0,000 0,11891955 0,16024294 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,11891955 0,16015461 ! neuron maturation GO:0042551 46 19 0,000 0,11891955 0,16006637 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,11891955 0,15997823 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,11891955 0,15989018 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,11891955 0,15980223 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,11891955 0,15971438 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,11891955 0,15962662 ! inositol metabolic process GO:0006020 33 19 0,000 0,11891955 0,15953897 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11891955 0,1594514 ! memory GO:0007613 34 19 0,000 0,11891955 0,15936394 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,11891955 0,15927657 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,11891955 0,15918929 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,11891955 0,15910211 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,11891955 0,15901503 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,11891955 0,15892804 ! cerebral cortex development GO:0021987 40 19 0,000 0,11891955 0,15884115 ! response to vitamin A GO:0033189 32 19 0,000 0,11891955 0,15875435 ! heme metabolic process GO:0042168 40 19 0,000 0,11891955 0,15866764 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,11891955 0,15858104 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,11891955 0,15849452 ! response to fungus GO:0009620 26 19 0,000 0,11891955 0,1584081 ! peptide cross-linking GO:0018149 39 19 0,000 0,11891955 0,15832177 ! protein export from nucleus GO:0006611 40 19 0,000 0,11891955 0,15823554 ! heart process GO:0003015 32 19 0,000 0,11891955 0,1581494 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,11891955 0,15806336 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,11891955 0,15797741 ! visual learning GO:0008542 38 19 0,000 0,11891955 0,15789155 ! cellular pigmentation GO:0033059 37 19 0,000 0,11891955 0,15780579 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,11891955 0,15772012 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,11891955 0,15763454 ! vitamin transport GO:0051180 31 19 0,000 0,11891955 0,15754905 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,11891955 0,15746366 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,11891955 0,15737836 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,11891955 0,15729315 ! cilium assembly GO:0042384 38 19 0,000 0,11891955 0,15720804 ! peptide hormone secretion GO:0030072 32 19 0,000 0,11891955 0,15712302 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,12268044 0,16200449 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,12268044 0,16191697 ! gland development GO:0048732 220 91 1,000 0,12268044 0,16182954 ! protein secretion GO:0009306 45 20 0,000 0,12477275 0,16450072 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,12477275 0,16441199 ! positive regulation of ossification GO:0045778 50 20 0,000 0,12477275 0,16432336 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,12477275 0,16423482 ! skin development GO:0043588 42 20 0,000 0,12477275 0,16414638 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,12477275 0,16405803 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,12477275 0,16396978 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,12477275 0,16388163 ! response to vitamin GO:0033273 36 20 0,000 0,12477275 0,16379357 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,12477275 0,1637056 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,12477275 0,16361773 GO:0010675|regulation of cellular carbohydrate metabolic process, ! bile acid metabolic process GO:0008206 34 20 0,000 0,12477275 0,16352995 ! retinoid metabolic process GO:0001523 34 20 0,000 0,12477275 0,16344227 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,12477275 0,16335468 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,12477275 0,16326718 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,12477275 0,16317978 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,12477275 0,16309247 ! body fluid secretion GO:0007589 33 20 0,000 0,12477275 0,16300526 ! peptide secretion GO:0002790 38 20 0,000 0,12477275 0,16291813 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,12477275 0,1628311 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,12477275 0,16274417 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,12477275 0,16265733 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,12477275 0,16257058 ! cell-cell junction organization GO:0045216 43 20 0,000 0,12477275 0,16248392 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,12477275 0,16239735 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,12477275 0,16231088 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,12477275 0,1622245 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,12477275 0,16213821 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,12477275 0,16205201 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,12477275 0,1619659 ! negative regulation of translation GO:0017148 32 20 0,000 0,12477275 0,16187989 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,12477275 0,16179396 ! bone development GO:0060348 206 92 1,000 0,12488331 0,16185141 ! regulation of membrane potential GO:0042391 179 94 1,000 0,12931735 0,16750916 ! regulation of cell killing GO:0031341 46 21 0,000 0,13058723 0,16906444 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,13058723 0,1689749 ! hormone secretion GO:0046879 39 21 0,000 0,13058723 0,16888545 ! cAMP metabolic process GO:0046058 41 21 0,000 0,13058723 0,16879609 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,13058723 0,16870682 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,13058723 0,16861766 ! ovarian follicle development GO:0001541 39 21 0,000 0,13058723 0,16852858 ! smooth muscle contraction GO:0006939 48 21 0,000 0,13058723 0,1684396 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,13058723 0,16835072 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,13058723 0,16826192 ! plasma membrane fusion GO:0045026 33 21 0,000 0,13058723 0,16817322 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,13058723 0,16808462 ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,13058723 0,16799611 ! sensory perception of pain GO:0019233 33 21 0,000 0,13058723 0,16790769 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,13058723 0,16781936 ! diencephalon development GO:0021536 36 21 0,000 0,13058723 0,16773113 ! collagen fibril organization GO:0030199 62 21 0,000 0,13058723 0,16764299 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,13058723 0,16755494 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,13058723 0,16746698 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,13058723 0,16737912 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,13058723 0,16729135 ! collagen catabolic process GO:0030574 29 21 0,000 0,13058723 0,16720367 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,13058723 0,16711608 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,13058723 0,16702859 ! sperm-egg recognition GO:0035036 23 21 0,000 0,13058723 0,16694119 ! actin filament-based movement GO:0030048 47 21 0,000 0,13058723 0,16685387 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,13154808 0,1679937 ! sex differentiation GO:0007548 171 96 1,000 0,13378766 0,1707645 ! regulation of protein localization GO:0032880 188 97 1,000 0,13603587 0,17354341 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,13636325 0,17387026 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,13636325 0,17377956 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,13636325 0,17368895 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,13636325 0,17359844 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,13636325 0,17350803 GO:0034105|positive regulation of tissue remodeling, ! glutamate signaling pathway GO:0007215 48 22 0,000 0,13636325 0,17341771 ! vacuolar transport GO:0007034 41 22 0,000 0,13636325 0,17332748 ! central nervous system neuron development GO:0021954 47 22 0,000 0,13636325 0,17323734 ! fucose metabolic process GO:0006004 44 22 0,000 0,13636325 0,1731473 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,13636325 0,17305736 ! ureteric bud development GO:0001657 50 22 0,000 0,13636325 0,1729675 ! stem cell differentiation GO:0048863 57 22 0,000 0,13636325 0,17287774 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,13636325 0,17278808 ! cytolysis GO:0019835 27 22 0,000 0,13636325 0,1726985 ! renal system process GO:0003014 42 22 0,000 0,13636325 0,17260902 ! vasodilation GO:0042311 40 22 0,000 0,13636325 0,17251963 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,13636325 0,17243034 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,13636325 0,17234113 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,13636325 0,17225202 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,13636325 0,172163 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,13636325 0,17207408 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,13636325 0,17198524 ! sarcomere organization GO:0045214 32 22 0,000 0,13636325 0,1718965 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,13636325 0,17180785 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,13636325 0,17171928 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,13636325 0,17163082 ! gut development GO:0048565 44 22 0,000 0,13636325 0,17154244 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,13636325 0,17145415 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,13636325 0,17136595 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,13636325 0,17127785 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,13829251 0,17361182 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,14210105 0,17830142 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,14210105 0,17820989 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,14210105 0,17811845 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,14210105 0,17802711 ! gluconeogenesis GO:0006094 38 23 0,000 0,14210105 0,17793586 ! glycerol metabolic process GO:0006071 40 23 0,000 0,14210105 0,17784471 ! viral genome replication GO:0019079 44 23 0,000 0,14210105 0,17775364 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,14210105 0,17766268 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,14210105 0,1775718 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,14210105 0,17748102 ! regeneration GO:0031099 42 23 0,000 0,14210105 0,17739033 ! axis specification GO:0009798 43 23 0,000 0,14210105 0,17729973 ! visual behavior GO:0007632 46 23 0,000 0,14210105 0,17720922 ! response to ethanol GO:0045471 47 23 0,000 0,14210105 0,17711881 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,14210105 0,17702849 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,14210105 0,17693826 ! peroxisome organization GO:0007031 43 23 0,000 0,14210105 0,17684812 ! lysosome organization GO:0007040 47 23 0,000 0,14210105 0,17675808 ! vesicle targeting GO:0006903 49 23 0,000 0,14210105 0,17666813 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,14210105 0,17657826 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,14210105 0,17648849 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,14210105 0,17639882 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,14210105 0,17630923 ! fatty acid transport GO:0015908 47 23 0,000 0,14210105 0,17621973 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,14210105 0,17613032 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,14210105 0,17604101 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,14210105 0,17595178 ! hormone transport GO:0009914 41 23 0,000 0,14210105 0,17586265 ! cell-cell recognition GO:0009988 28 23 0,000 0,14210105 0,1757736 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,14210105 0,17568465 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,14210105 0,17559579 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,14210105 0,17550701 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,14780089 0,18245457 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,14780089 0,18236242 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,14780089 0,18227036 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,14780089 0,1821784 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,14780089 0,18208653 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,14780089 0,18199475 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,14780089 0,18190307 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,14780089 0,18181147 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,14780089 0,18171997 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,14780089 0,18162856 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,14780089 0,18153725 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,14780089 0,18144602 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,14780089 0,18135489 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,14780089 0,18126385 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,14780089 0,1811729 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,14780089 0,18108204 ! membrane depolarization GO:0051899 45 24 0,000 0,14780089 0,18099127 ! pallium development GO:0021543 56 24 0,000 0,14780089 0,18090059 ! oogenesis GO:0048477 44 24 0,000 0,14780089 0,18081001 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,14780089 0,18071951 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,14780089 0,18062911 ! platelet activation GO:0030168 41 24 0,000 0,14780089 0,18053879 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,14780089 0,18044857 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,14780089 0,18035843 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,14780089 0,18026839 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,14780089 0,18017844 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,14780089 0,18008857 ! regulation of amine transport GO:0051952 41 24 0,000 0,14780089 0,1799988 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,15346303 0,18680128 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,15346303 0,18670826 ! leukocyte adhesion GO:0007159 55 25 0,000 0,15346303 0,18661532 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,15346303 0,18652248 ! phototransduction GO:0007602 37 25 0,000 0,15346303 0,18642973 ! keratinization GO:0031424 37 25 0,000 0,15346303 0,18633707 ! vacuole organization GO:0007033 49 25 0,000 0,15346303 0,1862445 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,15346303 0,18615203 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,15346303 0,18605964 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,15346303 0,18596735 ! interaction with host GO:0051701 66 25 0,000 0,15346303 0,18587515 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,15346303 0,18578304 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,15346303 0,18569102 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,15346303 0,1855991 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,15346303 0,18550726 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,15346303 0,18541552 ! liver development GO:0001889 55 25 0,000 0,15346303 0,18532387 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,1590877 0,19202137 ! initiation of viral infection GO:0019059 60 26 0,000 0,1590877 0,19192654 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,1590877 0,19183181 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,1590877 0,19173717 ! molting cycle process GO:0022404 52 26 0,000 0,1590877 0,19164263 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,1590877 0,19154818 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,1590877 0,19145382 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,1590877 0,19135955 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,1590877 0,19126538 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,1590877 0,1911713 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,1590877 0,19107731 ! digestive system process GO:0022600 49 26 0,000 0,1590877 0,19098342 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,1590877 0,19088961 ! osteoblast differentiation GO:0001649 63 26 0,000 0,1590877 0,1907959 ! neural crest cell development GO:0014032 59 26 0,000 0,1590877 0,19070228 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,1590877 0,19060876 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,1590877 0,19051532 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,1590877 0,19042198 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,1590877 0,19032872 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,1590877 0,19023556 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,1590877 0,19014249 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,1590877 0,19004951 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,1590877 0,18995662 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,1590877 0,18986383 ! blastocyst development GO:0001824 50 26 0,000 0,1590877 0,18977112 ! telomere organization GO:0032200 46 26 0,000 0,1590877 0,1896785 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,1590877 0,18958598 ! alditol metabolic process GO:0019400 44 26 0,000 0,1590877 0,18949354 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,1590877 0,1894012 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,1590877 0,18930894 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,16467516 0,19586242 ! embryonic pattern specification GO:0009880 49 27 0,000 0,16467516 0,19576711 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,16467516 0,19567189 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,16467516 0,19557677 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,16467516 0,19548173 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,16467516 0,19538679 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,16467516 0,19529195 ! iron ion transport GO:0006826 65 27 0,000 0,16467516 0,19519719 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,16467516 0,19510253 ! superoxide metabolic process GO:0006801 41 27 0,000 0,16467516 0,19500795 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,16467516 0,19491347 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,16467516 0,19481908 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,16467516 0,19472479 ! response to toxin GO:0009636 49 27 0,000 0,16467516 0,19463058 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,16467516 0,19453647 ! leukocyte proliferation GO:0070661 59 27 0,000 0,16467516 0,19444244 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,17022565 0,20089916 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,17022565 0,20080215 ! vesicle docking GO:0048278 55 28 0,000 0,17022565 0,20070524 ! circadian rhythm GO:0007623 56 28 0,000 0,17022565 0,20060842 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,17022565 0,20051169 ! sperm motility GO:0030317 37 28 0,000 0,17022565 0,20041506 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,17022565 0,20031852 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,17022565 0,20022208 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,17022565 0,20012572 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,17022565 0,20002946 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,17022565 0,19993329 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,17022565 0,19983722 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,17022565 0,19974124 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,17022565 0,19964534 ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,17022565 0,19954954 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,17022565 0,19945384 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,17573941 0,20581561 ! translational initiation GO:0006413 66 29 0,000 0,17573941 0,205717 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,17573941 0,20561847 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,17573941 0,20552004 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,17573941 0,20542171 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,17573941 0,20532347 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,17573941 0,20522532 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,17573941 0,20512727 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,17573941 0,20502931 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,17573941 0,20493144 ! synaptogenesis GO:0007416 46 29 0,000 0,17573941 0,20483367 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,17573941 0,20473599 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,17573941 0,2046384 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,17573941 0,20454091 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,17573941 0,20444351 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,18121668 0,21071507 ! phenol metabolic process GO:0018958 56 30 0,000 0,18121668 0,21061482 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,18121668 0,21051467 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,18121668 0,21041462 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,18121668 0,21031466 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,18121668 0,2102148 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,18121668 0,21011503 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,18121668 0,21001535 ! acute-phase response GO:0006953 50 30 0,000 0,18121668 0,20991577 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,18121668 0,20981628 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,18121668 0,20971689 ! myofibril assembly GO:0030239 50 30 0,000 0,18121668 0,20961759 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,18121668 0,20951839 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,18121668 0,20941928 ! cell fate determination GO:0001709 64 30 0,000 0,18121668 0,20932026 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,18121668 0,20922134 ! phospholipid transport GO:0015914 65 30 0,000 0,18121668 0,20912251 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,18121668 0,20902378 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,18121668 0,20892513 GO:0046496|nicotinamide nucleotide metabolic process, ! tissue homeostasis GO:0001894 50 30 0,000 0,18121668 0,20882658 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,18121668 0,20872813 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,18665772 0,21489388 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,18665772 0,21479265 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,18665772 0,21469153 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,18665772 0,2145905 ! regulation of innate immune response GO:0045088 57 31 0,000 0,18665772 0,21448956 ! ovulation cycle process GO:0022602 55 31 0,000 0,18665772 0,21438872 ! peptide transport GO:0015833 60 31 0,000 0,18665772 0,21428797 ! detection of light stimulus GO:0009583 44 31 0,000 0,18665772 0,21418732 ! natural killer cell activation GO:0030101 50 31 0,000 0,18665772 0,21408676 ! cofactor catabolic process GO:0051187 54 31 0,000 0,18665772 0,2139863 ! eye morphogenesis GO:0048592 65 31 0,000 0,18665772 0,21388593 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,18665772 0,21378566 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,19206275 0,21987314 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,19206275 0,21977016 ! collagen metabolic process GO:0032963 49 32 0,000 0,19206275 0,21966727 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,19206275 0,21956448 ! spindle organization GO:0007051 50 32 0,000 0,19206275 0,21946178 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,19206275 0,21935918 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,19206275 0,21925668 ! muscle cell development GO:0055001 52 32 0,000 0,19206275 0,21915427 ! mesoderm formation GO:0001707 73 32 0,000 0,19206275 0,21905196 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,19206275 0,21894974 ! ovulation cycle GO:0042698 57 32 0,000 0,19206275 0,21884762 ! BMP signaling pathway GO:0030509 71 32 0,000 0,19206275 0,21874559 ! hindbrain development GO:0030902 65 32 0,000 0,19206275 0,21864366 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,19206275 0,21854182 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,19206275 0,21844008 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,19206275 0,21833843 ! gene silencing GO:0016458 71 32 0,000 0,19206275 0,21823688 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,19743201 0,22423356 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,19743201 0,22412936 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,19743201 0,22402526 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,19743201 0,22392126 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,19743201 0,22381735 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,19743201 0,22371354 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,19743201 0,22360982 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,19743201 0,22350621 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,19743201 0,22340268 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,19743201 0,22329926 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,20276574 0,22922568 ! glial cell differentiation GO:0010001 67 34 0,000 0,20276574 0,22911965 ! post-embryonic development GO:0009791 76 34 0,000 0,20276574 0,22901373 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,20276574 0,2289079 ! cholesterol transport GO:0030301 62 34 0,000 0,20276574 0,22880217 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,20276574 0,22869653 ! spliceosome assembly GO:0000245 75 34 0,000 0,20276574 0,228591 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,20276574 0,22848556 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,20276574 0,22838022 ! formation of primary germ layer GO:0001704 76 34 0,000 0,20276574 0,22827497 ! cell fate specification GO:0001708 56 34 0,000 0,20276574 0,22816983 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,20276574 0,22806478 ! adult locomotory behavior GO:0008344 62 34 0,000 0,20276574 0,22795982 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,20276574 0,22785496 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,20806417 0,2337015 ! negative regulation of secretion GO:0051048 68 35 0,000 0,20806417 0,2335941 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,20806417 0,2334868 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,20806417 0,2333796 ! membrane docking GO:0022406 69 35 0,000 0,20806417 0,23327249 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,20806417 0,23316549 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,20806417 0,23305858 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,20806417 0,23295177 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,20806417 0,23284506 ! ceramide metabolic process GO:0006672 72 35 0,000 0,20806417 0,23273844 ! telencephalon development GO:0021537 81 35 0,000 0,20806417 0,23263193 ! sterol transport GO:0015918 63 35 0,000 0,20806417 0,23252551 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,20806417 0,23241919 ! placenta development GO:0001890 53 35 0,000 0,20806417 0,23231296 ! vesicle localization GO:0051648 70 35 0,000 0,20806417 0,23220683 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,21332753 0,23797222 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,21332753 0,23786361 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,21332753 0,23775509 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,21332753 0,23764668 ! positive regulation of cell development GO:0010720 85 36 0,000 0,21332753 0,23753836 ! protein targeting to membrane GO:0006612 75 36 0,000 0,21332753 0,23743014 ! regulation of proteolysis GO:0030162 77 36 0,000 0,21332753 0,23732202 ! aerobic respiration GO:0009060 56 36 0,000 0,21332753 0,237214 ! cytokine production GO:0001816 68 36 0,000 0,21332753 0,23710608 ! embryonic organ development GO:0048568 67 36 0,000 0,21332753 0,23699825 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,21332753 0,23689053 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,21332753 0,2367829 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,21855606 0,24247614 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,21855606 0,24236608 ! sister chromatid segregation GO:0000819 65 37 0,000 0,21855606 0,24225611 ! odontogenesis GO:0042476 74 37 0,000 0,21855606 0,24214624 ! actomyosin structure organization GO:0031032 68 37 0,000 0,21855606 0,24203648 ! tissue remodeling GO:0048771 78 37 0,000 0,21855606 0,24192681 ! female gonad development GO:0008585 71 37 0,000 0,21855606 0,24181724 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,22374999 0,24745189 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,22374999 0,24733992 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,22374999 0,24722805 ! organic anion transport GO:0015711 82 38 0,000 0,22374999 0,24711629 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,22374999 0,24700462 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,22374999 0,24689306 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,22374999 0,24678159 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,22374999 0,24667023 ! spermatid development GO:0007286 69 38 0,000 0,22374999 0,24655897 ! pigment metabolic process GO:0042440 87 38 0,000 0,22374999 0,2464478 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,22890954 0,25201713 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,22890954 0,25190361 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,22890954 0,25179019 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,22890954 0,25167687 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,22890954 0,25156366 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,22890954 0,25145054 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,22890954 0,25133753 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,23403494 0,25684967 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,23403494 0,25673434 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,23403494 0,2566191 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,23403494 0,25650398 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,23403494 0,25638895 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,23403494 0,25627403 ! RNA export from nucleus GO:0006405 61 41 0,000 0,23912642 0,26173201 ! mRNA catabolic process GO:0006402 79 41 0,000 0,23912642 0,2616148 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,23912642 0,26149769 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,23912642 0,26138069 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,23912642 0,26126379 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,23912642 0,261147 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,23912642 0,26103031 ! gliogenesis GO:0042063 91 41 0,000 0,23912642 0,26091373 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,23912642 0,26079725 ! mesenchymal cell development GO:0014031 94 41 0,000 0,23912642 0,26068087 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,23912642 0,2605646 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,23912642 0,26044843 ! RNA modification GO:0009451 64 41 0,000 0,23912642 0,26033237 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,24418419 0,26572026 ! organic ether metabolic process GO:0018904 59 42 0,000 0,24418419 0,26560195 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,24418419 0,26548375 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,24418419 0,26536565 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,24418419 0,26524766 ! regulation of protein secretion GO:0050708 77 42 0,000 0,24418419 0,26512977 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,24418419 0,26501199 ! cytokinesis GO:0000910 84 42 0,000 0,24418419 0,26489431 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,24418419 0,26477673 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,24920849 0,27010485 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,24920849 0,26998507 ! regulation of tube size GO:0035150 76 43 0,000 0,24920849 0,2698654 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,24920849 0,26974583 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,24920849 0,26962637 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,24920849 0,26950701 ! ion transmembrane transport GO:0034220 79 43 0,000 0,24920849 0,26938776 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,25419952 0,27466141 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,25419952 0,27453998 ! striated muscle contraction GO:0006941 85 44 0,000 0,25419952 0,27441866 ! phagocytosis GO:0006909 105 44 0,000 0,25419952 0,27429746 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,25419952 0,27417635 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,25915752 0,27940063 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,25915752 0,27927738 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,25915752 0,27915424 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,25915752 0,27903121 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,25915752 0,27890829 ! female gamete generation GO:0007292 71 45 0,000 0,25915752 0,27878548 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,25915752 0,27866278 ! polyol metabolic process GO:0019751 77 45 0,000 0,25915752 0,27854018 ! developmental growth GO:0048589 88 45 0,000 0,25915752 0,27841769 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,2640827 0,28358419 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,2640827 0,28345959 ! glycolysis GO:0006096 71 46 0,000 0,2640827 0,2833351 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,2640827 0,28321072 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,2640827 0,28308646 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,2640827 0,28296229 ! cell growth GO:0016049 90 46 0,000 0,2640827 0,28283824 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,26897527 0,28795205 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,27383545 0,29302672 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,27383545 0,29289843 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,27383545 0,29277024 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,27383545 0,29264217 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,27383545 0,29251421 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,27383545 0,29238637 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,27866345 0,29741145 ! JNK cascade GO:0007254 106 49 0,000 0,27866345 0,29728158 ! regulation of ion transport GO:0043269 86 50 0,000 0,28345949 0,30226606 ! endocrine system development GO:0035270 109 50 0,000 0,28345949 0,30213418 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,28345949 0,30200242 ! regulation of ossification GO:0030278 123 50 0,000 0,28345949 0,30187077 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,28345949 0,30173923 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,28345949 0,30160781 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,28345949 0,30147651 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,28822378 0,30641022 ! viral infectious cycle GO:0019058 104 51 0,000 0,28822378 0,30627694 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,28822378 0,30614378 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,29295652 0,31103554 ! Notch signaling pathway GO:0007219 111 52 0,000 0,29295652 0,31090043 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,29295652 0,31076543 ! excretion GO:0007588 87 52 0,000 0,29295652 0,31063055 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,29295652 0,31049578 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,29295652 0,31036114 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,29295652 0,31022661 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,29295652 0,31009219 ! amino acid activation GO:0043038 98 52 0,000 0,29295652 0,3099579 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,29765793 0,31479581 ! positive regulation of growth GO:0045927 96 53 0,000 0,29765793 0,31465959 ! inner ear development GO:0048839 89 53 0,000 0,29765793 0,31452349 ! chromatin remodeling GO:0006338 122 53 0,000 0,29765793 0,31438751 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,29765793 0,31425165 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,29765793 0,3141159 ! vesicle organization GO:0016050 127 53 0,000 0,29765793 0,31398027 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,3023282 0,31876901 ! neuromuscular process GO:0050905 107 54 0,000 0,3023282 0,31863149 ! membrane fusion GO:0006944 122 54 0,000 0,3023282 0,31849409 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,3023282 0,31835681 ! regulation of cell shape GO:0008360 142 54 0,000 0,3023282 0,31821964 ! RNA catabolic process GO:0006401 103 55 0,000 0,30696755 0,32296371 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,30696755 0,32282468 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,30696755 0,32268577 ! cell recognition GO:0008037 98 55 0,000 0,30696755 0,32254698 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,30696755 0,32240831 ! cell maturation GO:0048469 107 55 0,000 0,30696755 0,32226976 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,30696755 0,32213133 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,30696755 0,32199301 ! glucose catabolic process GO:0006007 88 56 0,000 0,31157618 0,32668696 ! RNA elongation GO:0006354 90 56 0,000 0,31157618 0,32654681 ! chloride transport GO:0006821 102 57 0,000 0,31615429 0,3312028 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,31615429 0,33106084 ! heart morphogenesis GO:0003007 105 57 0,000 0,31615429 0,330919 ! regulation of actin filament length GO:0030832 118 58 0,000 0,32070209 0,33553542 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,32070209 0,33539178 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,32070209 0,33524827 ! gastrulation GO:0007369 122 58 0,000 0,32070209 0,33510487 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,32070209 0,33496161 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,32070209 0,33481846 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,32070209 0,33467544 ! establishment of organelle localization GO:0051656 122 59 0,000 0,32521976 0,33924504 ! regulation of endocytosis GO:0030100 104 60 0,000 0,32970752 0,34377955 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,32970752 0,34363288 ! adult behavior GO:0030534 104 60 0,000 0,32970752 0,34348635 ! positive regulation of secretion GO:0051047 110 61 0,000 0,33416556 0,3479823 ! regulation of cellular component size GO:0032535 125 61 0,000 0,33416556 0,34783403 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,33416556 0,34768589 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,33416556 0,34753787 ! proton transport GO:0015992 117 61 0,000 0,33416556 0,34738999 ! viral reproductive process GO:0022415 132 62 0,000 0,33859407 0,35184403 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,33859407 0,35169444 ! tRNA processing GO:0008033 102 62 0,000 0,33859407 0,35154497 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,34299326 0,35596114 ! regulation of mitosis GO:0007088 112 63 0,000 0,34299326 0,35580999 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,34299326 0,35565897 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,34299326 0,35550807 ! hydrogen transport GO:0006818 121 64 0,000 0,3473633 0,35988488 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,3473633 0,35973232 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,3517044 0,36407367 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,3517044 0,36391947 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,3517044 0,36376539 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,3517044 0,36361145 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,35601675 0,3679141 ! activation of MAPK activity GO:0000187 124 67 0,000 0,36030053 0,3721836 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,36030053 0,37202629 ! secondary metabolic process GO:0019748 125 67 0,000 0,36030053 0,37186912 ! hexose catabolic process GO:0019320 113 68 0,000 0,36455594 0,37610226 ! extracellular matrix organization GO:0030198 146 68 0,000 0,36455594 0,3759435 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,36455594 0,37578488 ! viral reproduction GO:0016032 142 68 0,000 0,36455594 0,37562639 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,36455594 0,37546803 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,36878316 0,37966172 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,36878316 0,37950179 ! developmental maturation GO:0021700 128 69 0,000 0,36878316 0,379342 ! single fertilization GO:0007338 83 69 0,000 0,36878316 0,37918235 ! cell redox homeostasis GO:0045454 114 70 0,000 0,37298237 0,38333864 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,37298237 0,38317744 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,37715377 0,38729999 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,38129754 0,39139071 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,38129754 0,39122632 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,38129754 0,39106208 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,38129754 0,39089798 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,38129754 0,39073401 ! humoral immune response GO:0006959 115 73 0,000 0,38541385 0,39478659 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,38541385 0,39462113 ! regulation of immune effector process GO:0002697 156 73 0,000 0,38541385 0,39445581 ! acute inflammatory response GO:0002526 118 74 0,000 0,38950289 0,39847385 ! amino acid transport GO:0006865 148 74 0,000 0,38950289 0,39830705 ! organelle localization GO:0051640 155 74 0,000 0,38950289 0,3981404 ! transition metal ion transport GO:0000041 143 75 0,000 0,39356483 0,40212417 ! rhythmic process GO:0048511 142 75 0,000 0,39356483 0,40195606 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,39759987 0,40590743 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,39759987 0,40573788 ! regulation of blood pressure GO:0008217 134 76 0,000 0,39759987 0,40556847 ! amine catabolic process GO:0009310 136 77 0,000 0,40160817 0,40948613 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,40160817 0,4093153 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,40160817 0,40914461 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,40160817 0,40897406 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,40558992 0,41285673 ! antigen processing and presentation GO:0019882 117 78 0,000 0,40558992 0,41268478 ! fertilization GO:0009566 99 78 0,000 0,40558992 0,41251297 ! blood coagulation GO:0007596 151 79 0,000 0,40954527 0,41636251 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,40954527 0,41618931 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,40954527 0,41601626 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,40954527 0,41584335 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,41347442 0,4196585 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,41347442 0,41948423 ! exocytosis GO:0006887 153 83 0,000 0,42510634 0,43110618 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,42510634 0,4309273 ! inorganic anion transport GO:0015698 156 83 0,000 0,42510634 0,43074857 ! response to nutrient GO:0007584 135 84 0,000 0,42893238 0,43444519 ! digestion GO:0007586 130 84 0,000 0,42893238 0,43426514 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,43273305 0,43793158 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,43273305 0,43775025 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,43273305 0,43756906 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,440259 0,44499493 ! alcohol catabolic process GO:0046164 142 87 0,000 0,440259 0,4448109 ! nucleosome assembly GO:0006334 126 87 0,000 0,440259 0,44462701 ! cellular respiration GO:0045333 143 88 0,000 0,44398461 0,4482043 ! amine biosynthetic process GO:0009309 146 88 0,000 0,44398461 0,44801917 ! sensory perception of smell GO:0007608 117 88 0,000 0,44398461 0,44783419 ! chromatin assembly GO:0031497 128 88 0,000 0,44398461 0,44764936 ! cellular defense response GO:0006968 123 89 0,000 0,44768553 0,45119461 ! regulation of neurological system process GO:0031644 175 89 0,000 0,44768553 0,45100855 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,45136191 0,45452479 ! defense response to bacterium GO:0042742 112 91 0,000 0,45501393 0,45801361 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,45864174 0,46147519 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,4622455 0,46490974 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,4622455 0,46471842 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,4622455 0,46452725 ! vitamin metabolic process GO:0006766 153 93 0,000 0,4622455 0,46433625 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,46582537 0,46773998 ! female pregnancy GO:0007565 166 94 0,000 0,46582537 0,46754781 ! sterol metabolic process GO:0016125 166 94 0,000 0,46582537 0,4673558 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,46582537 0,46716395 ! nucleosome organization GO:0034728 143 95 0,000 0,46938151 0,47053715 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,46938151 0,47034415 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,46938151 0,4701513 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,46938151 0,46995862 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,47642323 0,47681358 ! forebrain development GO:0030900 210 98 0,000 0,47990911 0,48010563 ! mRNA transport GO:0051028 185 100 0,000 0,4868117 0,4868117