pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6622-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 3,000 2,55E-08 4,7E-05 GO:0032388|positive regulation of intracellular transport, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 2,000 5,642E-07 5,199E-04 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 9,493E-07 5,832E-04 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 1,312E-06 6,043E-04 ! positive regulation of protein transport GO:0051222 29 29 3,000 1,768E-06 6,515E-04 ! regulation of intracellular transport GO:0032386 31 31 3,000 2,332E-06 7,162E-04 ! positive regulation of protein import into nucleus GO:0042307 9 9 2,000 2,355E-06 6,2E-04 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 2,000 6,129E-06 1,412E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 1,26E-05 2,58E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 2,000 1,547E-05 2,852E-03 ! regulation of protein transport GO:0051223 53 53 3,000 2,072E-05 3,472E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of microtubule-based process GO:0032886 18 18 2,000 2,245E-05 3,448E-03 ! regulation of protein localization GO:0032880 58 57 3,000 2,772E-05 3,93E-03 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 3,637E-05 4,788E-03 ! positive regulation of transport GO:0051050 71 70 3,000 6,261E-05 7,692E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 9,705E-05 0,01117907 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 9,705E-05 0,01052148 ! receptor clustering GO:0043113 5 5 1,000 9,705E-05 9,937E-03 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 9,705E-05 9,414E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 9,705E-05 8,943E-03 ! postreplication repair GO:0006301 5 5 1,000 9,705E-05 8,517E-03 ! regulation of cellular localization GO:0060341 86 85 3,000 1,34E-04 0,0112225 ! virus-host interaction GO:0019048 6 6 1,000 1,453E-04 0,01164251 ! ER overload response GO:0006983 6 6 1,000 1,453E-04 0,01115741 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 1,453E-04 0,01071111 ! regulation of RNA splicing GO:0043484 6 6 1,000 1,453E-04 0,01029915 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,453E-04 9,918E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 1,453E-04 9,563E-03 ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 1,893E-04 0,01202832 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 2,03E-04 0,01247209 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 2,03E-04 0,01206976 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! axon cargo transport GO:0008088 7 7 1,000 2,03E-04 0,01169258 ! protein oligomerization GO:0051259 39 39 2,000 2,408E-04 0,01344587 ! negative regulation of microtubule depolymerization GO:0007026 8 8 1,000 2,702E-04 0,01464462 GO:0031114|regulation of microtubule depolymerization, ! sex determination GO:0007530 8 8 1,000 2,702E-04 0,0142262 ! peptidyl-serine modification GO:0018209 8 8 1,000 2,702E-04 0,01383103 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 2,702E-04 0,01345722 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 2,702E-04 0,01310308 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 1,000 3,467E-04 0,01638305 ! regulation of catabolic process GO:0009894 48 47 2,000 4,201E-04 0,01935804 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 4,325E-04 0,01944212 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 4,325E-04 0,01897921 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 4,325E-04 0,01853784 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 4,325E-04 0,01811652 ! protein stabilization GO:0050821 10 10 1,000 4,325E-04 0,01771393 ! phosphatidylinositol metabolic process GO:0046488 11 11 1,000 5,276E-04 0,02113869 ! signal complex assembly GO:0007172 11 11 1,000 5,276E-04 0,02068893 ! microtubule-based transport GO:0010970 11 11 1,000 5,276E-04 0,02025791 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 5,276E-04 0,01984448 ! intermediate filament-based process GO:0045103 11 11 1,000 5,276E-04 0,01944759 ! interaction with host GO:0051701 11 11 1,000 5,276E-04 0,01906627 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 5,276E-04 0,01869961 GO:0006109|regulation of carbohydrate metabolic process, ! positive regulation of DNA replication GO:0045740 14 13 1,000 7,453E-04 0,02591843 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 7,453E-04 0,02543846 ! receptor metabolic process GO:0043112 14 13 1,000 7,453E-04 0,02497594 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 7,453E-04 0,02452994 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 7,453E-04 0,02409959 ! protein tetramerization GO:0051262 13 13 1,000 7,453E-04 0,02368408 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 8,216E-04 0,02566607 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 9,995E-04 0,03070048 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 9,995E-04 0,03019719 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 9,995E-04 0,02971014 GO:0090048|negative regulation of transcription regulator activity, ! protein homooligomerization GO:0051260 15 15 1,000 9,995E-04 0,02923855 ! regulation of cytoskeleton organization GO:0051493 66 64 2,000 1,042E-03 0,03001174 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 1,14E-03 0,03232094 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 1,14E-03 0,03183488 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of synaptic plasticity GO:0048167 16 16 1,000 1,14E-03 0,03135973 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,14E-03 0,03089856 ! liver development GO:0001889 17 17 1,000 1,29E-03 0,03444408 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 1,448E-03 0,03812213 ! negative regulation of DNA binding GO:0043392 19 18 1,000 1,448E-03 0,03758519 ! negative regulation of catabolic process GO:0009895 18 18 1,000 1,448E-03 0,03706318 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 1,448E-03 0,03655546 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 1,615E-03 0,04022603 ! regulation of protein stability GO:0031647 19 19 1,000 1,615E-03 0,03968969 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 1,791E-03 0,04343522 ! negative regulation of binding GO:0051100 21 20 1,000 1,791E-03 0,04287113 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 1,791E-03 0,0423215 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 1,791E-03 0,04178578 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 1,976E-03 0,04551879 ! negative regulation of protein transport GO:0051224 21 21 1,000 1,976E-03 0,04495683 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 2,169E-03 0,04875498 ! maintenance of protein location in cell GO:0032507 23 22 1,000 2,169E-03 0,04816757 ! negative regulation of protein complex disassembly GO:0043242 23 23 1,000 2,371E-03 0,05202615 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 2,371E-03 0,05141407 ! positive regulation of growth GO:0045927 23 23 1,000 2,371E-03 0,05081624 ! glucose homeostasis GO:0042593 24 24 1,000 2,582E-03 0,05469277 GO:0033500|carbohydrate homeostasis, ! maintenance of protein location GO:0045185 25 24 1,000 2,582E-03 0,05407126 ! glucan metabolic process GO:0044042 25 24 1,000 2,582E-03 0,05346372 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of gene-specific transcription GO:0032583 25 25 1,000 2,801E-03 0,05735597 ! endosome transport GO:0016197 25 25 1,000 2,801E-03 0,05672569 ! heart morphogenesis GO:0003007 25 25 1,000 2,801E-03 0,0561091 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 3,028E-03 0,06001506 ! response to insulin stimulus GO:0032868 28 26 1,000 3,028E-03 0,0593766 ! maintenance of location in cell GO:0051651 27 26 1,000 3,028E-03 0,05875158 ! energy reserve metabolic process GO:0006112 28 27 1,000 3,264E-03 0,06266943 ! cAMP-mediated signaling GO:0019933 27 27 1,000 3,264E-03 0,06202335 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 3,509E-03 0,06598508 ! viral reproductive process GO:0022415 29 29 1,000 3,761E-03 0,07002146 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 3,761E-03 0,06932124 ! response to UV GO:0009411 29 29 1,000 3,761E-03 0,06863489 ! regulation of protein complex disassembly GO:0043244 30 30 1,000 4,022E-03 0,07267579 ! negative regulation of cytoskeleton organization GO:0051494 32 31 1,000 4,291E-03 0,07678509 ! regulation of DNA replication GO:0006275 32 31 1,000 4,291E-03 0,07604677 ! maintenance of location GO:0051235 33 32 1,000 4,569E-03 0,08018889 ! regulation of neuron differentiation GO:0045664 34 33 1,000 4,854E-03 0,08439381 ! regulation of synaptic transmission GO:0050804 33 33 1,000 4,854E-03 0,08360509 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 5,147E-03 0,08783802 ! regulation of protein catabolic process GO:0042176 35 34 1,000 5,147E-03 0,08703216 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 5,147E-03 0,08624096 ! viral reproduction GO:0016032 34 34 1,000 5,147E-03 0,08546402 ! positive regulation of cell migration GO:0030335 36 36 1,000 5,758E-03 0,09475192 ! female pregnancy GO:0007565 37 36 1,000 5,758E-03 0,09391341 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 5,758E-03 0,0930896 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 6,075E-03 0,09736505 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 1,000 6,075E-03 0,09652569 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 6,075E-03 0,09570069 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 6,075E-03 0,09488967 ! negative regulation of kinase activity GO:0033673 38 38 1,000 6,401E-03 0,09912801 ! regulation of neurological system process GO:0031644 38 38 1,000 6,401E-03 0,09830194 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 6,734E-03 0,10256102 ! activation of MAPK activity GO:0000187 39 39 1,000 6,734E-03 0,10172035 ! positive regulation of cell motion GO:0051272 39 39 1,000 6,734E-03 0,10089336 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 7,074E-03 0,10514387 ! negative regulation of transferase activity GO:0051348 40 40 1,000 7,074E-03 0,10430272 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 7,423E-03 0,10857155 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 1,000 7,423E-03 0,10771666 ! regulation of caspase activity GO:0043281 41 41 1,000 7,423E-03 0,10687512 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 7,779E-03 0,11113427 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 7,779E-03 0,11027939 ! negative regulation of ligase activity GO:0051352 43 42 1,000 7,779E-03 0,10943756 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 7,779E-03 0,10860849 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 8,143E-03 0,11283208 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 8,143E-03 0,11199005 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 8,514E-03 0,11622937 ! negative regulation of organelle organization GO:0010639 45 44 1,000 8,514E-03 0,11537474 ! homophilic cell adhesion GO:0007156 45 45 1,000 8,893E-03 0,11962868 ! regulation of DNA binding GO:0051101 47 45 1,000 8,893E-03 0,11876181 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 8,893E-03 0,11790741 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 8,893E-03 0,11706521 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 9,279E-03 0,1212842 ! regulation of peptidase activity GO:0052547 46 46 1,000 9,279E-03 0,12043008 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 9,279E-03 0,11958791 ! positive regulation of ligase activity GO:0051351 47 46 1,000 9,279E-03 0,11875744 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 9,279E-03 0,11793842 ! actin filament organization GO:0007015 50 48 1,000 0,01007376 0,12716399 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,01007376 0,12629893 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,01007376 0,12544556 ! cell cycle arrest GO:0007050 49 49 1,000 0,0104822 0,1296557 ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 0,0104822 0,12879133 ! regulation of ligase activity GO:0051340 50 49 1,000 0,0104822 0,1279384 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,01089793 0,13213742 ! negative regulation of transport GO:0051051 51 50 1,000 0,01089793 0,13127378 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,01089793 0,13042135 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01089793 0,12957992 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01089793 0,12874928 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,01175107 0,13794409 ! response to light stimulus GO:0009416 53 52 1,000 0,01175107 0,13707102 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,01308429 0,15166253 ! reproductive developmental process GO:0003006 56 56 1,000 0,01354278 0,15599591 ! regulation of nervous system development GO:0051960 57 56 1,000 0,01354278 0,15502699 ! regulation of binding GO:0051098 60 57 1,000 0,01400824 0,15936537 ! regulation of cell development GO:0060284 60 59 1,000 0,01495989 0,1691477 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,01544598 0,17357896 ! rRNA transcription GO:0009303 5 5 0,000 0,01589104 0,17749808 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,01589104 0,17642881 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,01589104 0,17537235 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,01589104 0,17432847 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,01589104 0,17329694 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,01589104 0,17227755 ! reproductive cellular process GO:0048610 5 5 0,000 0,01589104 0,17127008 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,01589104 0,17027432 ! prostate gland development GO:0030850 5 5 0,000 0,01589104 0,16929007 ! metencephalon development GO:0022037 5 5 0,000 0,01589104 0,16831714 ! water transport GO:0006833 5 5 0,000 0,01589104 0,16735533 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,01589104 0,16640445 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,01589104 0,16546431 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,01589104 0,16453474 ! glycerol metabolic process GO:0006071 5 5 0,000 0,01589104 0,16361555 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,01589104 0,16270657 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,01589104 0,16180764 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,01589104 0,16091859 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,01589104 0,16003925 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,01589104 0,15916947 ! filopodium assembly GO:0046847 7 5 0,000 0,01589104 0,1583091 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,01589104 0,15745797 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,01589104 0,15661595 ! GTP metabolic process GO:0046039 5 5 0,000 0,01589104 0,15578289 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,01589104 0,15495864 ! mRNA stabilization GO:0048255 5 5 0,000 0,01589104 0,15414307 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,01589104 0,15333604 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,01589104 0,15253741 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,01589104 0,15174706 ! social behavior GO:0035176 5 5 0,000 0,01589104 0,15096486 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,01589104 0,15019068 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,01589104 0,1494244 ! memory GO:0007613 5 5 0,000 0,01589104 0,1486659 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,01589104 0,14791507 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,01589104 0,14717177 ! response to lipid GO:0033993 5 5 0,000 0,01589104 0,14643591 ! erythrocyte maturation GO:0043249 5 5 0,000 0,01589104 0,14570738 ! hippocampus development GO:0021766 6 5 0,000 0,01589104 0,14498605 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,01589104 0,14427184 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,01589104 0,14356462 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,01589104 0,14286431 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,01589104 0,14217079 ! mechanosensory behavior GO:0007638 5 5 0,000 0,01589104 0,14148398 ! heart looping GO:0001947 5 5 0,000 0,01589104 0,14080376 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,01589104 0,14013006 ! response to interferon-gamma GO:0034341 5 5 0,000 0,01589104 0,13946278 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,01589104 0,13880181 ! endocrine pancreas development GO:0031018 5 5 0,000 0,01589104 0,13814709 ! pH reduction GO:0045851 5 5 0,000 0,01589104 0,13749851 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,01589104 0,13685599 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,01589104 0,13621946 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,01589104 0,13558881 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,01589104 0,13496398 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,01589104 0,13434488 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,01589104 0,13373143 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,01589104 0,13312356 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,01589104 0,13252119 ! adrenal gland development GO:0030325 5 5 0,000 0,01589104 0,13192425 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,01589104 0,13133266 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,01589104 0,13074635 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,01589104 0,13016526 ! astrocyte differentiation GO:0048708 5 5 0,000 0,01589104 0,1295893 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,01589104 0,12901843 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,01589104 0,12845256 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,01589104 0,12789163 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,01589104 0,12733558 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,01589104 0,12678434 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,01589104 0,12623786 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,01589104 0,12569606 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,01589104 0,1251589 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,01589104 0,12462631 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,01589104 0,12409823 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,01589104 0,12357461 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,01589104 0,12305539 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,01589104 0,12254051 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,01589104 0,12202993 ! response to ATP GO:0033198 5 5 0,000 0,01589104 0,12152358 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,01589104 0,12102142 ! regulation of appetite GO:0032098 5 5 0,000 0,01589104 0,12052339 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,01589104 0,12002944 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,01589104 0,11953952 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,01589104 0,11905359 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,01589104 0,11857159 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,01589104 0,11809348 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01589104 0,11761921 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,01589104 0,11714873 ! fear response GO:0042596 5 5 0,000 0,01589104 0,116682 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,01589104 0,11621898 ! retinol metabolic process GO:0042572 5 5 0,000 0,01589104 0,11575962 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,01589104 0,11530387 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,01589104 0,1148517 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,01589104 0,11440306 ! parturition GO:0007567 5 5 0,000 0,01589104 0,11395791 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01589104 0,11351621 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,01589104 0,11307793 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,01589104 0,11264301 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,01589104 0,11221143 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,01589104 0,11178314 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,01589104 0,11135811 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,01589104 0,1109363 ! response to UV-B GO:0010224 5 5 0,000 0,01589104 0,11051767 ! oligodendrocyte development GO:0014003 5 5 0,000 0,01589104 0,11010219 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,01589104 0,10968982 ! activated T cell proliferation GO:0050798 5 5 0,000 0,01589104 0,10928053 ! interaction with symbiont GO:0051702 5 5 0,000 0,01589104 0,10887429 ! cellular extravasation GO:0045123 5 5 0,000 0,01589104 0,10847105 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,01589104 0,10807079 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,01589104 0,10767347 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,01589104 0,10727906 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,01589104 0,10688753 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,01589104 0,10649885 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,01589104 0,10611298 ! response to amine stimulus GO:0014075 5 5 0,000 0,01589104 0,1057299 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,01589104 0,10534958 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,01589104 0,10497198 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,01589104 0,10459708 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,01589104 0,10422485 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,01589104 0,10385526 ! neuron recognition GO:0008038 5 5 0,000 0,01589104 0,10348828 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,01589104 0,10312388 ! decidualization GO:0046697 5 5 0,000 0,01589104 0,10276205 ! hair follicle maturation GO:0048820 5 5 0,000 0,01589104 0,10240274 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,01589104 0,10204593 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,01589104 0,10169161 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,01589104 0,10133973 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,01589104 0,10099029 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,01589104 0,10064324 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,01589104 0,10029857 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,01589104 0,09995626 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,01589104 0,09961627 ! histone methylation GO:0016571 5 5 0,000 0,01589104 0,09927859 ! DNA methylation GO:0006306 5 5 0,000 0,01589104 0,09894319 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01589104 0,09861004 ! T cell lineage commitment GO:0002360 5 5 0,000 0,01589104 0,09827914 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,01589104 0,09795044 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,01589104 0,09762394 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,01589104 0,09729961 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,01589104 0,09697743 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,01589104 0,09665737 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,01589104 0,09633942 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,01589104 0,09602355 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,01589104 0,09570975 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,01589104 0,09539799 ! sterol catabolic process GO:0016127 5 5 0,000 0,01589104 0,09508826 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,01589104 0,09478053 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,01589104 0,09447478 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,01589104 0,09417101 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,01589104 0,09386918 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,01589104 0,09356927 ! zymogen activation GO:0031638 5 5 0,000 0,01589104 0,09327128 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,01589104 0,09297518 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,01589104 0,09268096 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,01589104 0,09238859 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,01589104 0,09209806 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,01589104 0,09180935 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,01589104 0,09152245 ! nucleosome positioning GO:0016584 5 5 0,000 0,01589104 0,09123733 ! regulation of isotype switching GO:0045191 5 5 0,000 0,01589104 0,09095398 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,01589104 0,09067239 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,01589104 0,09039254 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,01589104 0,09011441 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,01589104 0,08983798 ! NADPH regeneration GO:0006740 5 5 0,000 0,01589104 0,08956325 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,01589104 0,08929019 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,01589104 0,08901879 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,01589104 0,08874904 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,01589104 0,08848092 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,01589104 0,08821441 ! sarcomere organization GO:0045214 5 5 0,000 0,01589104 0,0879495 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,01589104 0,08768618 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,01589104 0,08742443 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,01589104 0,08716423 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,01589104 0,08690559 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,01589104 0,08664847 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,01589104 0,08639287 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,01589104 0,08613877 ! spleen development GO:0048536 5 5 0,000 0,01589104 0,08588617 ! male genitalia development GO:0030539 5 5 0,000 0,01589104 0,08563504 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,01589104 0,08538537 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,01589104 0,08513716 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,01589104 0,08489039 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,01589104 0,08464504 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,01589104 0,0844011 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,01589104 0,08415857 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,01589104 0,08391743 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,01589104 0,08367767 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,01589104 0,08343927 ! ATP catabolic process GO:0006200 5 5 0,000 0,01589104 0,08320222 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01589104 0,08296652 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,01589104 0,08273216 ! blastocyst formation GO:0001825 5 5 0,000 0,01589104 0,08249911 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,01589104 0,08226737 ! embryonic gut development GO:0048566 5 5 0,000 0,01589104 0,08203693 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,01589104 0,08180777 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,01589104 0,0815799 ! activation of innate immune response GO:0002218 5 5 0,000 0,01589104 0,08135329 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,01589104 0,08112793 ! catecholamine transport GO:0051937 5 5 0,000 0,01589104 0,08090382 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,01589104 0,08068094 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,01589104 0,08045929 ! muscle adaptation GO:0043500 5 5 0,000 0,01589104 0,08023886 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,01589104 0,08001963 ! embryonic heart tube development GO:0035050 5 5 0,000 0,01589104 0,07980159 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,01589104 0,07958474 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,01589104 0,07936906 ! defense response to fungus GO:0050832 5 5 0,000 0,01589104 0,07915455 ! lysogeny GO:0030069 5 5 0,000 0,01589104 0,07894119 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,01589104 0,07872899 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,01589104 0,07851792 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,01589104 0,07830798 ! response to nicotine GO:0035094 5 5 0,000 0,01589104 0,07809915 ! establishment of cell polarity GO:0030010 5 5 0,000 0,01589104 0,07789144 ! mitochondrion localization GO:0051646 5 5 0,000 0,01589104 0,07768484 ! nucleus localization GO:0051647 5 5 0,000 0,01589104 0,07747932 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,01589104 0,07727489 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,01593887 0,07730352 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,01694483 0,08196673 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,01745782 0,08422713 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,01850359 0,08903949 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,01850359 0,08880761 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,01904019 0,09114562 ! axon extension GO:0048675 7 6 0,000 0,01904019 0,09090949 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,01904019 0,09067458 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,01904019 0,09044089 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,01904019 0,09020839 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,01904019 0,08997709 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,01904019 0,08974697 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,01904019 0,08951802 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,01904019 0,08929024 ! regulation of S phase GO:0033261 6 6 0,000 0,01904019 0,08906361 ! myotube differentiation GO:0014902 6 6 0,000 0,01904019 0,08883814 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,01904019 0,0886138 ! bone remodeling GO:0046849 6 6 0,000 0,01904019 0,08839059 ! N-glycan processing GO:0006491 6 6 0,000 0,01904019 0,0881685 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,01904019 0,08794753 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,01904019 0,08772766 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,01904019 0,08750889 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,01904019 0,0872912 ! RNA methylation GO:0001510 6 6 0,000 0,01904019 0,0870746 ! cartilage condensation GO:0001502 7 6 0,000 0,01904019 0,08685907 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,01904019 0,0866446 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,01904019 0,08643119 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,01904019 0,08621883 ! artery development GO:0060840 6 6 0,000 0,01904019 0,08600751 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,01904019 0,08579722 ! bile acid metabolic process GO:0008206 6 6 0,000 0,01904019 0,08558796 ! androgen metabolic process GO:0008209 6 6 0,000 0,01904019 0,08537972 ! estrogen metabolic process GO:0008210 6 6 0,000 0,01904019 0,08517249 ! limbic system development GO:0021761 7 6 0,000 0,01904019 0,08496626 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,01904019 0,08476102 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,01904019 0,08455678 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,01904019 0,08435352 ! pathogenesis GO:0009405 6 6 0,000 0,01904019 0,08415123 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,01904019 0,08394991 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,01904019 0,08374956 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,01904019 0,08355015 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,01904019 0,0833517 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,01904019 0,08315418 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,01904019 0,0829576 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,01904019 0,08276194 ! arginine metabolic process GO:0006525 6 6 0,000 0,01904019 0,08256721 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,01904019 0,08237339 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,01904019 0,08218048 ! glutamate catabolic process GO:0006538 7 6 0,000 0,01904019 0,08198847 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,01904019 0,08179735 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,01904019 0,08160713 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,01904019 0,08141778 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,01904019 0,08122931 ! V(D)J recombination GO:0033151 6 6 0,000 0,01904019 0,08104172 ! focal adhesion formation GO:0048041 7 6 0,000 0,01904019 0,08085499 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,01904019 0,08066911 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,01904019 0,08048409 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,01904019 0,08029992 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,01904019 0,08011658 ! regulation of heart rate GO:0002027 6 6 0,000 0,01904019 0,07993409 ! lipid digestion GO:0044241 6 6 0,000 0,01904019 0,07975242 ! asymmetric protein localization GO:0008105 6 6 0,000 0,01904019 0,07957157 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,01904019 0,07939155 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,01904019 0,07921233 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,01904019 0,07903393 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,01904019 0,07885632 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,01904019 0,07867952 ! ruffle organization GO:0031529 6 6 0,000 0,01904019 0,0785035 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,01904019 0,07832827 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,01904019 0,07815382 ! neutral amino acid transport GO:0015804 6 6 0,000 0,01904019 0,07798014 ! L-amino acid transport GO:0015807 6 6 0,000 0,01904019 0,07780724 ! bone mineralization GO:0030282 6 6 0,000 0,01904019 0,0776351 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,01904019 0,07746372 ! negative regulation of ossification GO:0030279 6 6 0,000 0,01904019 0,07729309 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,01904019 0,07712322 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,01904019 0,07695409 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,01904019 0,0767857 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,01904019 0,07661804 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,01904019 0,07645112 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,01904019 0,07628492 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,01904019 0,07611944 ! regulation of organ growth GO:0046620 6 6 0,000 0,01904019 0,07595468 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,01904019 0,07579063 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,01904019 0,07562729 ! response to dsRNA GO:0043331 6 6 0,000 0,01904019 0,07546465 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,01904019 0,07530271 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,01904019 0,07514146 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,01904019 0,07498091 ! genitalia development GO:0048806 6 6 0,000 0,01904019 0,07482103 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,01904019 0,07466184 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,01904019 0,07450332 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,01904019 0,07434547 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,01904019 0,0741883 ! multicellular organismal aging GO:0010259 6 6 0,000 0,01904019 0,07403178 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,01904019 0,07387592 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,01904019 0,07372072 ! erythrocyte development GO:0048821 6 6 0,000 0,01904019 0,07356617 ! renal water homeostasis GO:0003091 6 6 0,000 0,01904019 0,07341227 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,01904019 0,07325901 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,01904019 0,07310638 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,01904019 0,07295439 ! ribosome assembly GO:0042255 6 6 0,000 0,01904019 0,07280304 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,01904019 0,07265231 ! diencephalon development GO:0021536 6 6 0,000 0,01904019 0,0725022 ! fucose catabolic process GO:0019317 6 6 0,000 0,01904019 0,07235271 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,01904019 0,07220384 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,01904019 0,07205557 ! regulation of lipid transport GO:0032368 6 6 0,000 0,01904019 0,07190792 ! regulation of cell division GO:0051302 6 6 0,000 0,01904019 0,07176087 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,01904019 0,07161442 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,01904019 0,07146856 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,01904019 0,0713233 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,01904019 0,07117863 ! neuroblast proliferation GO:0007405 6 6 0,000 0,01904019 0,07103454 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,01904019 0,07089104 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,01904019 0,07074811 ! regulation of glucose transport GO:0010827 6 6 0,000 0,01904019 0,07060576 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,01904019 0,07046398 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,01904019 0,07032277 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,01904019 0,07018213 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,01904019 0,07004204 ! thymus development GO:0048538 6 6 0,000 0,01904019 0,06990252 ! lymph node development GO:0048535 6 6 0,000 0,01904019 0,06976355 ! organic cation transport GO:0015695 6 6 0,000 0,01904019 0,06962513 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,01904019 0,06948726 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,01904019 0,06934993 ! sperm-egg recognition GO:0035036 7 6 0,000 0,01904019 0,06921314 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,01904019 0,0690769 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,01904019 0,06894119 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,01904019 0,06880601 ! alditol metabolic process GO:0019400 6 6 0,000 0,01904019 0,06867136 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,01904019 0,06853723 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,01904019 0,06840363 ! maternal placenta development GO:0001893 6 6 0,000 0,01904019 0,06827055 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,01904019 0,06813799 ! localization within membrane GO:0051668 6 6 0,000 0,01904019 0,06800594 ! response to radiation GO:0009314 70 68 1,000 0,01957548 0,0697826 ! sensory perception of sound GO:0007605 71 69 1,000 0,0201211 0,07158916 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,0201211 0,07145123 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,0201211 0,07131382 ! regulation of cell migration GO:0030334 71 71 1,000 0,0212315 0,0751049 ! respiratory burst GO:0045730 7 7 0,000 0,02217971 0,07830884 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02217971 0,07815911 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02217971 0,07800995 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02217971 0,07786136 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02217971 0,07771333 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02217971 0,07756587 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02217971 0,07741897 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02217971 0,07727262 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02217971 0,07712682 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02217971 0,07698157 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02217971 0,07683687 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02217971 0,07669271 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02217971 0,07654909 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02217971 0,07640601 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02217971 0,07626346 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02217971 0,07612144 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02217971 0,07597995 ! axis specification GO:0009798 7 7 0,000 0,02217971 0,07583899 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02217971 0,07569854 ! visual behavior GO:0007632 7 7 0,000 0,02217971 0,07555862 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02217971 0,07541921 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02217971 0,07528032 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02217971 0,07514194 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02217971 0,07500406 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02217971 0,07486669 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02217971 0,07472982 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02217971 0,07459346 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02217971 0,07445758 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02217971 0,07432221 ! digestive system development GO:0055123 7 7 0,000 0,02217971 0,07418732 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02217971 0,07405292 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02217971 0,07391901 ! protein targeting to ER GO:0045047 8 7 0,000 0,02217971 0,07378559 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02217971 0,07365264 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02217971 0,07352017 ! endoderm development GO:0007492 7 7 0,000 0,02217971 0,07338818 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02217971 0,07325666 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02217971 0,07312561 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02217971 0,07299503 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02217971 0,07286491 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02217971 0,07273526 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02217971 0,07260606 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02217971 0,07247733 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,02217971 0,07234905 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02217971 0,07222123 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02217971 0,07209385 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02217971 0,07196693 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02217971 0,07184045 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02217971 0,07171441 ! response to X-ray GO:0010165 7 7 0,000 0,02217971 0,07158882 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,02217971 0,07146366 ! UV protection GO:0009650 7 7 0,000 0,02217971 0,07133894 ! DNA integration GO:0015074 7 7 0,000 0,02217971 0,07121466 ! myofibril assembly GO:0030239 7 7 0,000 0,02217971 0,07109081 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02217971 0,07096739 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02217971 0,07084439 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02217971 0,07072182 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02217971 0,07059968 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02217971 0,07047796 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02217971 0,07035665 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02217971 0,07023576 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02217971 0,07011529 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02217971 0,06999523 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02217971 0,06987558 ! eating behavior GO:0042755 7 7 0,000 0,02217971 0,06975634 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02217971 0,0696375 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02217971 0,06951907 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02217971 0,06940104 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02217971 0,06928341 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02217971 0,06916618 ! cranial nerve development GO:0021545 7 7 0,000 0,02217971 0,06904935 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02217971 0,06893291 ! induction of an organ GO:0001759 7 7 0,000 0,02217971 0,06881686 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02217971 0,0687012 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02217971 0,06858593 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02217971 0,06847105 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02217971 0,06835655 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02217971 0,06824243 ! platelet activation GO:0030168 8 7 0,000 0,02217971 0,06812869 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02217971 0,06801533 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02217971 0,06790235 ! natural killer cell activation GO:0030101 7 7 0,000 0,02217971 0,06778974 ! response to gamma radiation GO:0010332 8 7 0,000 0,02217971 0,06767751 ! NADP metabolic process GO:0006739 7 7 0,000 0,02217971 0,06756564 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02217971 0,06745415 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02217971 0,06734302 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02217971 0,06723226 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02217971 0,06712186 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02217971 0,06701183 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02217971 0,06690215 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02217971 0,06679283 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02217971 0,06668387 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02217971 0,06657527 ! cell-cell recognition GO:0009988 8 7 0,000 0,02217971 0,06646701 ! hormone catabolic process GO:0042447 7 7 0,000 0,02217971 0,06635911 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02217971 0,06625156 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02217971 0,06614436 ! oxygen transport GO:0015671 7 7 0,000 0,02217971 0,0660375 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02217971 0,06593099 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02217971 0,06582482 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02217971 0,06571899 ! regulation of axon extension GO:0030516 7 7 0,000 0,02217971 0,06561351 ! cell killing GO:0001906 7 7 0,000 0,02217971 0,06550836 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02217971 0,06540354 ! adult feeding behavior GO:0008343 7 7 0,000 0,02217971 0,06529906 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02217971 0,06519492 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02217971 0,06509111 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02217971 0,06498762 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,02217971 0,06488447 ! response to cold GO:0009409 7 7 0,000 0,02217971 0,06478164 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02530965 0,07380646 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02530965 0,07368987 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02530965 0,07357364 ! positive regulation of translation GO:0045727 8 8 0,000 0,02530965 0,07345777 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02530965 0,07334227 ! superoxide anion generation GO:0042554 8 8 0,000 0,02530965 0,07322714 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02530965 0,07311236 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02530965 0,07299794 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02530965 0,07288388 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02530965 0,07277018 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02530965 0,07265683 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02530965 0,07254383 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,02530965 0,07243119 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02530965 0,07231889 ! zinc ion transport GO:0006829 8 8 0,000 0,02530965 0,07220694 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02530965 0,07209534 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02530965 0,07198408 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02530965 0,07187317 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02530965 0,07176259 ! lipid localization GO:0010876 8 8 0,000 0,02530965 0,07165236 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02530965 0,07154246 ! response to cAMP GO:0051591 8 8 0,000 0,02530965 0,0714329 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02530965 0,07132368 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02530965 0,07121479 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02530965 0,07110623 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02530965 0,070998 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02530965 0,0708901 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02530965 0,07078253 ! sensory perception of taste GO:0050909 8 8 0,000 0,02530965 0,07067528 ! organelle fusion GO:0048284 8 8 0,000 0,02530965 0,07056836 ! pancreas development GO:0031016 8 8 0,000 0,02530965 0,07046176 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02530965 0,07035548 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02530965 0,07024953 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02530965 0,07014389 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02530965 0,07003857 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02530965 0,06993356 ! sperm motility GO:0030317 8 8 0,000 0,02530965 0,06982887 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02530965 0,06972449 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02530965 0,06962043 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02530965 0,06951667 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02530965 0,06941322 ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02530965 0,06931008 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02530965 0,06920725 ! Golgi organization GO:0007030 8 8 0,000 0,02530965 0,06910472 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02530965 0,06900249 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02530965 0,06890057 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,02530965 0,06879895 ! fructose metabolic process GO:0006000 8 8 0,000 0,02530965 0,06869762 ! mannose metabolic process GO:0006013 9 8 0,000 0,02530965 0,0685966 ! NAD metabolic process GO:0019674 8 8 0,000 0,02530965 0,06849587 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02530965 0,06839543 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02530965 0,06829529 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,02530965 0,06819545 ! response to fungus GO:0009620 8 8 0,000 0,02530965 0,06809589 ! stem cell differentiation GO:0048863 8 8 0,000 0,02530965 0,06799663 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02530965 0,06789765 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02530965 0,06779896 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02530965 0,06770056 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02530965 0,06760244 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02530965 0,06750461 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02530965 0,06740706 ! vasoconstriction GO:0042310 8 8 0,000 0,02530965 0,06730979 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02530965 0,0672128 ! muscle cell development GO:0055001 8 8 0,000 0,02530965 0,06711609 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02530965 0,06701966 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02530965 0,06692351 ! sensory perception of pain GO:0019233 8 8 0,000 0,02530965 0,06682763 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02530965 0,06673202 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02530965 0,06663669 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02530965 0,06654163 ! chromatin silencing GO:0006342 8 8 0,000 0,02530965 0,06644684 ! tissue regeneration GO:0042246 8 8 0,000 0,02530965 0,06635233 ! salivary gland development GO:0007431 8 8 0,000 0,02530965 0,06625808 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02530965 0,06616409 ! T cell homeostasis GO:0043029 8 8 0,000 0,02530965 0,06607038 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02530965 0,06597692 ! water homeostasis GO:0030104 8 8 0,000 0,02530965 0,06588374 ! cofactor transport GO:0051181 8 8 0,000 0,02530965 0,06579081 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02530965 0,06569815 ! acid secretion GO:0046717 8 8 0,000 0,02530965 0,06560575 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02530965 0,0655136 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02530965 0,06542172 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02530965 0,06533009 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02530965 0,06523872 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02530965 0,0651476 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02530965 0,06505674 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02530965 0,06496614 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02530965 0,06487578 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02530965 0,06478567 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,02530965 0,06469582 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02530965 0,06460621 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02530965 0,06451685 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02530965 0,06442774 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02530965 0,06433888 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02530965 0,06425026 ! developmental induction GO:0031128 8 8 0,000 0,02530965 0,06416188 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02530965 0,06407374 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02530965 0,06398585 ! actin filament polymerization GO:0030041 9 8 0,000 0,02530965 0,0638982 ! peptide hormone processing GO:0016486 8 8 0,000 0,02530965 0,06381079 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02530965 0,06372361 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02530965 0,06363668 ! microtubule-based movement GO:0007018 82 78 1,000 0,02531456 0,06356232 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,02531456 0,06347584 ! regulation of locomotion GO:0040012 79 79 1,000 0,02592228 0,06491135 ! regulation of cell motion GO:0051270 79 79 1,000 0,02592228 0,06482328 ! MAPKKK cascade GO:0000165 82 81 1,000 0,02715561 0,06781542 ! lactation GO:0007595 10 9 0,000 0,02843002 0,07090193 ! embryonic pattern specification GO:0009880 10 9 0,000 0,02843002 0,07080612 ! positive regulation of cell size GO:0045793 9 9 0,000 0,02843002 0,07071056 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,02843002 0,07061527 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,02843002 0,07052023 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,02843002 0,07042544 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,02843002 0,07033091 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,02843002 0,07023663 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,02843002 0,07014261 ! viral genome replication GO:0019079 9 9 0,000 0,02843002 0,07004883 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,02843002 0,06995531 ! copper ion transport GO:0006825 9 9 0,000 0,02843002 0,06986204 ! lipid phosphorylation GO:0046834 9 9 0,000 0,02843002 0,06976901 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,02843002 0,06967623 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,02843002 0,0695837 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,02843002 0,06949142 ! RNA polyadenylation GO:0043631 9 9 0,000 0,02843002 0,06939938 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,02843002 0,06930758 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,02843002 0,06921602 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,02843002 0,06912471 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,02843002 0,06903363 ! phospholipid efflux GO:0033700 9 9 0,000 0,02843002 0,0689428 ! response to alkaloid GO:0043279 10 9 0,000 0,02843002 0,06885221 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,02843002 0,06876185 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,02843002 0,06867173 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,02843002 0,06858184 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,02843002 0,06849219 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,02843002 0,06840278 ! response to ethanol GO:0045471 9 9 0,000 0,02843002 0,0683136 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,02843002 0,06822465 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,02843002 0,06813593 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,02843002 0,06804744 ! methionine metabolic process GO:0006555 9 9 0,000 0,02843002 0,06795918 ! glutamine metabolic process GO:0006541 9 9 0,000 0,02843002 0,06787115 ! cerebral cortex development GO:0021987 9 9 0,000 0,02843002 0,06778335 ! response to osmotic stress GO:0006970 9 9 0,000 0,02843002 0,06769577 ! pigmentation during development GO:0048066 9 9 0,000 0,02843002 0,06760842 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,02843002 0,0675213 ! central nervous system neuron development GO:0021954 10 9 0,000 0,02843002 0,0674344 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,02843002 0,06734772 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,02843002 0,06726127 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,02843002 0,06717504 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,02843002 0,06708902 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,02843002 0,06700323 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,02843002 0,06691766 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,02843002 0,06683231 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,02843002 0,06674717 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,02843002 0,06666225 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,02843002 0,06657755 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,02843002 0,06649306 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,02843002 0,06640878 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,02843002 0,06632472 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,02843002 0,06624087 ! DNA replication initiation GO:0006270 9 9 0,000 0,02843002 0,06615723 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,02843002 0,06607381 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,02843002 0,06599059 ! regulation of cellular pH GO:0030641 9 9 0,000 0,02843002 0,06590758 ! histone acetylation GO:0016573 9 9 0,000 0,02843002 0,06582478 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,02843002 0,06574219 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,02843002 0,06565981 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,02843002 0,06557763 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,02843002 0,06549566 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,02843002 0,06541389 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,02843002 0,06533233 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,02843002 0,06525097 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,02843002 0,06516981 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,02843002 0,06508886 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,02843002 0,0650081 ! collagen catabolic process GO:0030574 9 9 0,000 0,02843002 0,06492754 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,02843002 0,06484719 ! purine base metabolic process GO:0006144 9 9 0,000 0,02843002 0,06476703 ! gas transport GO:0015669 9 9 0,000 0,02843002 0,06468707 ! cholesterol efflux GO:0033344 9 9 0,000 0,02843002 0,06460731 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,02843002 0,06452774 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,02843002 0,06444837 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,02843002 0,0643692 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,02843002 0,06429022 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,02843002 0,06421143 ! defense response to virus GO:0051607 9 9 0,000 0,02843002 0,06413284 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,02843002 0,06405444 ! actin filament-based movement GO:0030048 9 9 0,000 0,02843002 0,06397623 ! positive regulation of protein kinase activity GO:0045860 89 86 1,000 0,03034148 0,06819432 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,03034148 0,06811125 GO:0006644|phospholipid metabolic process, ! heart development GO:0007507 90 87 1,000 0,03099591 0,06949569 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03154085 0,07063159 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03154085 0,07054587 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03154085 0,07046036 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03154085 0,07037505 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03154085 0,07028996 ! neuron maturation GO:0042551 10 10 0,000 0,03154085 0,07020507 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03154085 0,07012038 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03154085 0,0700359 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03154085 0,06995162 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03154085 0,06986754 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03154085 0,06978367 ! hormone secretion GO:0046879 10 10 0,000 0,03154085 0,06969999 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03154085 0,06961652 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03154085 0,06953325 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,03154085 0,06945017 ! inositol metabolic process GO:0006020 10 10 0,000 0,03154085 0,0693673 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03154085 0,06928462 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03154085 0,06920214 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03154085 0,06911985 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03154085 0,06903776 ! glial cell development GO:0021782 10 10 0,000 0,03154085 0,06895587 ! phototransduction GO:0007602 11 10 0,000 0,03154085 0,06887416 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03154085 0,06879266 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,03154085 0,06871134 ! fat cell differentiation GO:0045444 10 10 0,000 0,03154085 0,06863022 ! myoblast differentiation GO:0045445 10 10 0,000 0,03154085 0,06854929 ! centrosome cycle GO:0007098 10 10 0,000 0,03154085 0,06846855 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03154085 0,06838799 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03154085 0,06830763 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03154085 0,06822746 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03154085 0,06814747 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03154085 0,06806768 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03154085 0,06798806 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03154085 0,06790864 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03154085 0,0678294 ! plasma membrane organization GO:0007009 10 10 0,000 0,03154085 0,06775034 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03154085 0,06767147 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03154085 0,06759279 ! lysosomal transport GO:0007041 10 10 0,000 0,03154085 0,06751428 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03154085 0,06743596 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03154085 0,06735782 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03154085 0,06727986 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03154085 0,06720208 ! exocrine system development GO:0035272 10 10 0,000 0,03154085 0,06712447 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03154085 0,06704705 ! neuromuscular junction development GO:0007528 10 10 0,000 0,03154085 0,06696981 ! embryo implantation GO:0007566 11 10 0,000 0,03154085 0,06689274 ! regulation of protein binding GO:0043393 11 10 0,000 0,03154085 0,06681586 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03154085 0,06673914 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03154085 0,06666261 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03154085 0,06658625 ! protein export from nucleus GO:0006611 10 10 0,000 0,03154085 0,06651006 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03154085 0,06643405 ! cytolysis GO:0019835 10 10 0,000 0,03154085 0,06635821 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03154085 0,06628255 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03154085 0,06620706 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03154085 0,06613174 ! histone deacetylation GO:0016575 10 10 0,000 0,03154085 0,06605659 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03154085 0,06598161 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03154085 0,0659068 ! gland morphogenesis GO:0022612 10 10 0,000 0,03154085 0,06583216 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03154085 0,06575769 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03154085 0,06568338 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03154085 0,06560925 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03154085 0,06553528 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03154085 0,06546148 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03154085 0,06538785 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03154085 0,06531438 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03154085 0,06524107 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03154085 0,06516793 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03154085 0,06509496 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03154085 0,06502214 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03154085 0,06494949 ! nerve development GO:0021675 10 10 0,000 0,03154085 0,064877 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,03154085 0,06480468 ! gut development GO:0048565 10 10 0,000 0,03154085 0,06473251 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03154085 0,06466051 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,03154085 0,06458866 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03154085 0,06451698 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03154085 0,06444545 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03154085 0,06437408 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03154085 0,06430287 ! positive regulation of transferase activity GO:0051347 91 88 1,000 0,031656 0,06446631 GO:0033674|positive regulation of kinase activity, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,03299301 0,06711493 ! DNA replication GO:0006260 91 91 1,000 0,03366985 0,06841625 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,0343522 0,06972588 ! protein secretion GO:0009306 11 11 0,000 0,03464218 0,07023711 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,03464218 0,07015993 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,03464218 0,07008292 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,03464218 0,07000607 ! negative regulation of defense response GO:0031348 11 11 0,000 0,03464218 0,06992939 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,03464218 0,06985288 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,03464218 0,06977654 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,03464218 0,06970037 ! skin development GO:0043588 11 11 0,000 0,03464218 0,06962436 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,03464218 0,06954852 ! endothelial cell migration GO:0043542 11 11 0,000 0,03464218 0,06947284 ! peroxisomal transport GO:0043574 11 11 0,000 0,03464218 0,06939732 ! protein amino acid methylation GO:0006479 11 11 0,000 0,03464218 0,06932197 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,03464218 0,06924679 ! heart contraction GO:0060047 11 11 0,000 0,03464218 0,06917176 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,03464218 0,0690969 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,03464218 0,0690222 ! T cell proliferation GO:0042098 11 11 0,000 0,03464218 0,06894766 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,03464218 0,06887329 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,03464218 0,06879907 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,03464218 0,06872501 ! spinal cord development GO:0021510 11 11 0,000 0,03464218 0,06865111 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,03464218 0,06857738 ! smooth muscle contraction GO:0006939 11 11 0,000 0,03464218 0,06850379 ! cellular response to starvation GO:0009267 11 11 0,000 0,03464218 0,06843037 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,03464218 0,06835711 ! digestive system process GO:0022600 11 11 0,000 0,03464218 0,068284 ! mitotic spindle organization GO:0007052 11 11 0,000 0,03464218 0,06821104 ! fucose metabolic process GO:0006004 11 11 0,000 0,03464218 0,06813825 ! membrane budding GO:0006900 11 11 0,000 0,03464218 0,0680656 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,03464218 0,06799312 ! monoamine transport GO:0015844 11 11 0,000 0,03464218 0,06792078 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,03464218 0,0678486 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,03464218 0,06777658 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,03464218 0,0677047 ! body fluid secretion GO:0007589 11 11 0,000 0,03464218 0,06763298 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,03464218 0,06756141 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,03464218 0,06749 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,03464218 0,06741873 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,03464218 0,06734761 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,03464218 0,06727665 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,03464218 0,06720583 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,03464218 0,06713516 ! oogenesis GO:0048477 11 11 0,000 0,03464218 0,06706464 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,03464218 0,06699427 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,03464218 0,06692404 ! vitamin transport GO:0051180 11 11 0,000 0,03464218 0,06685397 ! muscle maintenance GO:0046716 12 11 0,000 0,03464218 0,06678403 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,03464218 0,06671425 ! hindbrain development GO:0030902 11 11 0,000 0,03464218 0,06664461 ! steroid catabolic process GO:0006706 11 11 0,000 0,03464218 0,06657512 ! endocrine process GO:0050886 11 11 0,000 0,03464218 0,06650577 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,03464218 0,06643656 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,03464218 0,0663675 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,03464218 0,06629858 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,03464218 0,06622981 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,03464218 0,06616118 ! pattern specification process GO:0007389 96 94 1,000 0,03573324 0,0681743 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,03773402 0,07191707 ! translational initiation GO:0006413 12 12 0,000 0,03773402 0,07184277 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,03773402 0,07176863 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,03773402 0,07169464 ! initiation of viral infection GO:0019059 12 12 0,000 0,03773402 0,07162081 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,03773402 0,07154712 ! iron ion transport GO:0006826 13 12 0,000 0,03773402 0,07147359 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,03773402 0,07140021 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,03773402 0,07132698 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,03773402 0,0712539 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,03773402 0,07118097 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,03773402 0,07110818 ! collagen metabolic process GO:0032963 12 12 0,000 0,03773402 0,07103555 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,03773402 0,07096307 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,03773402 0,07089073 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,03773402 0,07081854 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,03773402 0,07074649 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,03773402 0,0706746 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,03773402 0,07060285 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,03773402 0,07053124 ! actomyosin structure organization GO:0031032 12 12 0,000 0,03773402 0,07045978 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,03773402 0,07038847 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,03773402 0,07031729 ! retinoid metabolic process GO:0001523 12 12 0,000 0,03773402 0,07024627 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,03773402 0,07017538 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,03773402 0,07010464 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,03773402 0,07003404 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,03773402 0,06996359 ! acute-phase response GO:0006953 12 12 0,000 0,03773402 0,06989327 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,03773402 0,0698231 ! vacuolar transport GO:0007034 12 12 0,000 0,03773402 0,06975306 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,03773402 0,06968317 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,03773402 0,06961342 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,03773402 0,0695438 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,03773402 0,06947433 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,03773402 0,06940499 ! male gonad development GO:0008584 12 12 0,000 0,03773402 0,0693358 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,03773402 0,06926674 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,03773402 0,06919782 ! renal system process GO:0003014 12 12 0,000 0,03773402 0,06912903 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,03773402 0,06906038 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,03773402 0,06899187 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,03773402 0,06892349 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,03773402 0,06885525 ! pallium development GO:0021543 13 12 0,000 0,03773402 0,06878715 ! cell fate determination GO:0001709 12 12 0,000 0,03773402 0,06871917 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,03773402 0,06865134 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,03773402 0,06858363 ! somitogenesis GO:0001756 13 12 0,000 0,03773402 0,06851606 ! G1 phase GO:0051318 13 12 0,000 0,03773402 0,06844863 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,03773402 0,06838132 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,03773402 0,06831415 ! detection of light stimulus GO:0009583 13 12 0,000 0,03773402 0,06824711 ! synaptogenesis GO:0007416 12 12 0,000 0,03773402 0,0681802 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,03773402 0,06811342 ! hormone transport GO:0009914 12 12 0,000 0,03773402 0,06804678 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,03773402 0,06798026 ! heme biosynthetic process GO:0006783 12 12 0,000 0,03773402 0,06791387 ! spermatid differentiation GO:0048515 13 12 0,000 0,03773402 0,06784761 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,03773402 0,06778149 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,03773402 0,06771549 ! neural tube closure GO:0001843 13 12 0,000 0,03773402 0,06764961 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,03773402 0,06758387 ! negative regulation of translation GO:0017148 12 12 0,000 0,03773402 0,06751826 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,03773402 0,06745277 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,0385597 0,06886195 ! regulation of system process GO:0044057 98 98 1,000 0,0385597 0,06879529 ! response to hormone stimulus GO:0009725 102 100 1,000 0,04000451 0,07130398 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,04081641 0,07268082 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04081641 0,07261066 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04081641 0,07254064 ! phenol metabolic process GO:0018958 13 13 0,000 0,04081641 0,07247076 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04081641 0,07240101 ! gluconeogenesis GO:0006094 13 13 0,000 0,04081641 0,07233139 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04081641 0,07226191 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04081641 0,07219256 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04081641 0,07212334 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04081641 0,07205426 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04081641 0,07198531 ! regeneration GO:0031099 13 13 0,000 0,04081641 0,07191649 ! keratinization GO:0031424 13 13 0,000 0,04081641 0,0718478 ! post-embryonic development GO:0009791 14 13 0,000 0,04081641 0,07177924 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04081641 0,07171082 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04081641 0,07164252 ! vasculogenesis GO:0001570 13 13 0,000 0,04081641 0,07157436 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04081641 0,07150632 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04081641 0,07143841 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,04081641 0,07137063 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,04081641 0,07130298 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04081641 0,07123546 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04081641 0,07116807 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04081641 0,0711008 ! autophagy GO:0006914 13 13 0,000 0,04081641 0,07103366 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04081641 0,07096665 ! ureteric bud development GO:0001657 13 13 0,000 0,04081641 0,07089976 ! cell aging GO:0007569 13 13 0,000 0,04081641 0,070833 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,04081641 0,07076637 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,04081641 0,07069986 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04081641 0,07063347 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04081641 0,07056721 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04081641 0,07050108 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04081641 0,07043506 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04081641 0,07036918 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04081641 0,07030341 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04081641 0,07023777 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04081641 0,07017225 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04081641 0,07010685 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04081641 0,07004157 ! vasodilation GO:0042311 14 13 0,000 0,04081641 0,06997642 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04081641 0,06991138 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04081641 0,06984647 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04081641 0,06978168 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04081641 0,069717 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04081641 0,06965245 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04081641 0,06958802 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04081641 0,0695237 ! immunoglobulin production GO:0002377 13 13 0,000 0,04081641 0,06945951 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04081641 0,06939543 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,04081641 0,06933147 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,04081641 0,06926763 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04081641 0,06920391 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,04081641 0,0691403 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04081641 0,06907681 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04081641 0,06901344 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04081641 0,06895018 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04081641 0,06888704 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04081641 0,06882401 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04081641 0,0687611 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04081641 0,06869831 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04081641 0,06863563 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04081641 0,06857306 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04081641 0,06851061 ! blastocyst development GO:0001824 13 13 0,000 0,04081641 0,06844827 ! telomere organization GO:0032200 13 13 0,000 0,04081641 0,06838604 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04081641 0,06832393 ! regulation of amine transport GO:0051952 13 13 0,000 0,04081641 0,06826193 ! tissue homeostasis GO:0001894 13 13 0,000 0,04081641 0,06820004 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04081641 0,06813827 ! neuron fate commitment GO:0048663 14 14 0,000 0,04388938 0,07320192 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,04388938 0,07313573 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,04388938 0,07306967 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,04388938 0,07300372 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,04388938 0,07293789 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,04388938 0,07287218 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,04388938 0,07280659 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,04388938 0,07274111 ! protein amino acid acylation GO:0043543 14 14 0,000 0,04388938 0,07267576 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,04388938 0,07261052 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,04388938 0,0725454 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,04388938 0,07248039 ! vesicle docking GO:0048278 14 14 0,000 0,04388938 0,07241551 ! superoxide metabolic process GO:0006801 15 14 0,000 0,04388938 0,07235073 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,04388938 0,07228608 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,04388938 0,07222154 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,04388938 0,07215711 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,04388938 0,0720928 ! hair cycle GO:0042633 14 14 0,000 0,04388938 0,0720286 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,04388938 0,07196452 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,04388938 0,07190055 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,04388938 0,0718367 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,04388938 0,07177295 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,04388938 0,07170933 ! lysosome organization GO:0007040 14 14 0,000 0,04388938 0,07164581 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,04388938 0,07158241 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,04388938 0,07151912 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,04388938 0,07145594 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,04388938 0,07139287 ! primary neural tube formation GO:0014020 15 14 0,000 0,04388938 0,07132991 ! peptide cross-linking GO:0018149 14 14 0,000 0,04388938 0,07126707 ! regulation of behavior GO:0050795 14 14 0,000 0,04388938 0,07120433 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,04388938 0,07114171 ! base-excision repair GO:0006284 14 14 0,000 0,04388938 0,07107919 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,04388938 0,07101679 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,04388938 0,07095449 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,04388938 0,0708923 ! formation of primary germ layer GO:0001704 14 14 0,000 0,04388938 0,07083023 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,04388938 0,07076826 ! collagen fibril organization GO:0030199 14 14 0,000 0,04388938 0,0707064 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,04388938 0,07064465 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,04388938 0,070583 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,04388938 0,07052146 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,04388938 0,07046003 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,04388938 0,07039871 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,04388938 0,0703375 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,04388938 0,07027639 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,04388938 0,07021538 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,04388938 0,07015448 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,04695294 0,07498637 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,04695294 0,07492144 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,04695294 0,07485663 ! positive regulation of ossification GO:0045778 15 15 0,000 0,04695294 0,07479193 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,04695294 0,07472735 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,04695294 0,07466287 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,04695294 0,07459851 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,04695294 0,07453425 ! response to vitamin GO:0033273 15 15 0,000 0,04695294 0,07447011 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,04695294 0,07440608 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,04695294 0,07434216 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,04695294 0,07427834 ! ovarian follicle development GO:0001541 15 15 0,000 0,04695294 0,07421464 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,04695294 0,07415104 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,04695294 0,07408756 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,04695294 0,07402418 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,04695294 0,07396091 ! heme metabolic process GO:0042168 15 15 0,000 0,04695294 0,07389775 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,04695294 0,0738347 ! chromosome condensation GO:0030261 15 15 0,000 0,04695294 0,07377176 ! response to starvation GO:0042594 15 15 0,000 0,04695294 0,07370892 ! response to ionizing radiation GO:0010212 16 15 0,000 0,04695294 0,07364619 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,04695294 0,07358356 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,04695294 0,07352104 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,04695294 0,07345863 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,04695294 0,07339633 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,04695294 0,07333413 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,04695294 0,07327203 ! phospholipid transport GO:0015914 15 15 0,000 0,04695294 0,07321004 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,04695294 0,07314816 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,04695294 0,07308638 ! glutathione metabolic process GO:0006749 16 15 0,000 0,04695294 0,0730247 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,04695294 0,07296313 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,04695294 0,07290166 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,04695294 0,07284029 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,04695294 0,07277903 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,04695294 0,07271787 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,04695294 0,07265682 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,04695294 0,07259586 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,05000713 0,07725327 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05000713 0,07718856 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05000713 0,07712397 ! learning GO:0007612 16 16 0,000 0,05000713 0,07705949 ! circadian rhythm GO:0007623 16 16 0,000 0,05000713 0,07699511 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05000713 0,07693084 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,05000713 0,07686668 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,05000713 0,07680262 ! vacuole organization GO:0007033 16 16 0,000 0,05000713 0,07673867 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,05000713 0,07667483 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05000713 0,07661109 ! vesicle targeting GO:0006903 17 16 0,000 0,05000713 0,07654746 ! segmentation GO:0035282 17 16 0,000 0,05000713 0,07648394 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05000713 0,07642052 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,05000713 0,07635721 ! iron ion homeostasis GO:0055072 16 16 0,000 0,05000713 0,076294 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05000713 0,07623089 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05000713 0,07616789 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05000713 0,07610499 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05000713 0,0760422 ! cell fate specification GO:0001708 16 16 0,000 0,05000713 0,07597951 ! pentose metabolic process GO:0019321 16 16 0,000 0,05000713 0,07591692 ! fatty acid transport GO:0015908 16 16 0,000 0,05000713 0,07585444 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05000713 0,07579206 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,05000713 0,07572978 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05000713 0,07566761 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05000713 0,07560553 ! polyol metabolic process GO:0019751 16 16 0,000 0,05000713 0,07554356 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05000713 0,07548169 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05000713 0,07541992 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05000713 0,07535826 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05000713 0,07529669 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,05000713 0,07523522 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05000713 0,07517386 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05000713 0,07511259 ! regulation of coagulation GO:0050818 17 16 0,000 0,05000713 0,07505142 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,05305198 0,07955639 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,05305198 0,07949171 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,05305198 0,07942713 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,05305198 0,07936266 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,05305198 0,0792983 ! myelination GO:0042552 17 17 0,000 0,05305198 0,07923404 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,05305198 0,07916988 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,05305198 0,07910583 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,05305198 0,07904188 ! leukocyte adhesion GO:0007159 17 17 0,000 0,05305198 0,07897803 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,05305198 0,07891429 ! sensory perception of smell GO:0007608 17 17 0,000 0,05305198 0,07885065 ! glucose transport GO:0015758 17 17 0,000 0,05305198 0,07878711 ! cell junction assembly GO:0034329 18 17 0,000 0,05305198 0,07872367 ! tissue remodeling GO:0048771 17 17 0,000 0,05305198 0,07866034 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,05305198 0,07859711 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,05305198 0,07853398 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,05305198 0,07847095 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,05305198 0,07840802 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,05305198 0,07834519 ! neural crest cell development GO:0014032 19 17 0,000 0,05305198 0,07828247 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,05305198 0,07821984 ! negative regulation of cell development GO:0010721 18 17 0,000 0,05305198 0,07815732 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,05305198 0,07809489 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,05305198 0,07803256 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,05305198 0,07797034 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,05305198 0,07790821 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,05305198 0,07784618 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,05305198 0,07778425 ! pigmentation GO:0043473 17 17 0,000 0,05305198 0,07772242 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,05305198 0,07766069 ! adult locomotory behavior GO:0008344 17 17 0,000 0,05305198 0,07759905 ! embryonic organ development GO:0048568 17 17 0,000 0,05305198 0,07753751 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,05305198 0,07747607 ! gene silencing GO:0016458 17 17 0,000 0,05305198 0,07741473 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,05608751 0,0817795 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,05608751 0,08171485 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,05608751 0,08165031 ! meiosis I GO:0007127 18 18 0,000 0,05608751 0,08158586 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,05608751 0,08152152 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,05608751 0,08145728 ! membrane docking GO:0022406 18 18 0,000 0,05608751 0,08139314 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,05608751 0,0813291 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,05608751 0,08126516 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,05608751 0,08120133 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,05608751 0,08113759 ! hexose transport GO:0008645 18 18 0,000 0,05608751 0,08107395 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,05608751 0,08101041 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,05608751 0,08094698 ! striated muscle contraction GO:0006941 18 18 0,000 0,05608751 0,08088364 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,05608751 0,0808204 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,05608751 0,08075726 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,05608751 0,08069421 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,05608751 0,08063127 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,05608751 0,08056842 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,05608751 0,08050568 ! B cell differentiation GO:0030183 18 18 0,000 0,05608751 0,08044303 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,05608751 0,08038047 ! ensheathment of neurons GO:0007272 18 18 0,000 0,05608751 0,08031802 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,05608751 0,08025566 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,05608751 0,0801934 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,05911376 0,08445477 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,05911376 0,08438935 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,05911376 0,08432404 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,05911376 0,08425882 ! glial cell differentiation GO:0010001 19 19 0,000 0,05911376 0,0841937 ! regulation of pH GO:0006885 19 19 0,000 0,05911376 0,08412869 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,05911376 0,08406378 ! feeding behavior GO:0007631 19 19 0,000 0,05911376 0,08399896 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,05911376 0,08393425 ! peroxisome organization GO:0007031 19 19 0,000 0,05911376 0,08386963 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,05911376 0,08380512 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,05911376 0,0837407 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,05911376 0,08367638 ! metanephros development GO:0001656 19 19 0,000 0,05911376 0,08361217 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,05911376 0,08354805 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,05911376 0,08348403 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,05911376 0,0834201 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,05911376 0,08335628 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,05911376 0,08329255 ! peripheral nervous system development GO:0007422 19 19 0,000 0,05911376 0,08322892 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,05911376 0,08316538 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,05911376 0,08310195 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,05911376 0,08303861 ! eye morphogenesis GO:0048592 19 19 0,000 0,05911376 0,08297536 ! regulation of cell shape GO:0008360 21 19 0,000 0,05911376 0,08291222 ! placenta development GO:0001890 19 19 0,000 0,05911376 0,08284917 ! response to heat GO:0009408 19 19 0,000 0,05911376 0,08278621 ! vesicle localization GO:0051648 20 19 0,000 0,05911376 0,08272335 ! regulation of muscle development GO:0048634 21 20 0,000 0,06213074 0,08687932 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,06213074 0,08681345 ! organic ether metabolic process GO:0018904 20 20 0,000 0,06213074 0,08674769 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,06213074 0,08668202 ! nucleus organization GO:0006997 20 20 0,000 0,06213074 0,08661645 ! phagocytosis GO:0006909 21 20 0,000 0,06213074 0,08655098 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,06213074 0,08648561 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,06213074 0,08642034 ! protein targeting to membrane GO:0006612 22 20 0,000 0,06213074 0,08635516 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,06213074 0,08629009 ! chromatin remodeling GO:0006338 20 20 0,000 0,06213074 0,08622511 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,06213074 0,08616023 ! lipid oxidation GO:0034440 20 20 0,000 0,06213074 0,08609545 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,06213074 0,08603076 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,06213074 0,08596618 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,06213074 0,08590169 ! RNA modification GO:0009451 20 20 0,000 0,06213074 0,08583729 ! single fertilization GO:0007338 21 20 0,000 0,06213074 0,08577299 ! regulation of B cell activation GO:0050864 20 20 0,000 0,06213074 0,08570879 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,06513848 0,08979074 ! mRNA catabolic process GO:0006402 21 21 0,000 0,06513848 0,08972363 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,06513848 0,08965662 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,06513848 0,08958972 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,06513848 0,08952291 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,06513848 0,0894562 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,06513848 0,08938959 ! Notch signaling pathway GO:0007219 22 21 0,000 0,06513848 0,08932308 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,06513848 0,08925667 ! ear morphogenesis GO:0042471 21 21 0,000 0,06513848 0,08919036 ! organic anion transport GO:0015711 21 21 0,000 0,06513848 0,08912414 ! cholesterol transport GO:0030301 21 21 0,000 0,06513848 0,08905803 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,06513848 0,08899201 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,06513848 0,08892609 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,06513848 0,08886027 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,06513848 0,08879454 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,06513848 0,08872891 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,06513848 0,08866338 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,06513848 0,08859795 ! regulation of proteolysis GO:0030162 21 21 0,000 0,06513848 0,08853261 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,06513848 0,08846737 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,06513848 0,08840222 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,06813702 0,09240362 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,06813702 0,09233568 ! sister chromatid segregation GO:0000819 22 22 0,000 0,06813702 0,09226783 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,06813702 0,09220009 ! regulation of ion transport GO:0043269 22 22 0,000 0,06813702 0,09213244 ! odontogenesis GO:0042476 22 22 0,000 0,06813702 0,0920649 ! cell junction organization GO:0034330 23 22 0,000 0,06813702 0,09199745 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,06813702 0,0919301 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,06813702 0,09186285 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,06813702 0,0917957 ! ovulation cycle process GO:0022602 22 22 0,000 0,06813702 0,09172865 ! spindle organization GO:0007051 22 22 0,000 0,06813702 0,09166169 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,06813702 0,09159484 ! cell chemotaxis GO:0060326 23 22 0,000 0,06813702 0,09152808 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,06813702 0,09146141 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,06813702 0,09139485 ! male sex differentiation GO:0046661 22 22 0,000 0,06813702 0,09132838 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,06813702 0,09126201 ! biopolymer methylation GO:0043414 22 22 0,000 0,06813702 0,09119573 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,06813702 0,09112955 ! detection of external stimulus GO:0009581 23 22 0,000 0,06813702 0,09106347 ! neuron migration GO:0001764 22 22 0,000 0,06813702 0,09099748 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,06813702 0,09093159 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,06813702 0,09086579 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,06813702 0,09080009 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,06813702 0,09073448 ! aerobic respiration GO:0009060 22 22 0,000 0,06813702 0,09066897 ! cytokine production GO:0001816 22 22 0,000 0,06813702 0,09060355 ! cytokinesis GO:0000910 23 22 0,000 0,06813702 0,09053823 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,06813702 0,090473 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,07112637 0,0943743 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,07112637 0,0943064 ! viral infectious cycle GO:0019058 23 23 0,000 0,07112637 0,0942386 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,07112637 0,0941709 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,07112637 0,0941033 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,07112637 0,09403579 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,07112637 0,09396839 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,07112637 0,09390107 ! endocrine system development GO:0035270 23 23 0,000 0,07112637 0,09383386 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,07112637 0,09376674 ! female gonad development GO:0008585 23 23 0,000 0,07112637 0,09369971 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,07112637 0,09363278 ! lipid homeostasis GO:0055088 23 23 0,000 0,07112637 0,09356595 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,07112637 0,09349921 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,07112637 0,09343257 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,07112637 0,09336602 ! cell projection assembly GO:0030031 25 23 0,000 0,07112637 0,09329957 ! mitochondrial transport GO:0006839 24 24 0,000 0,07410657 0,09713969 ! regulation of action potential GO:0001508 24 24 0,000 0,07410657 0,09707065 ! gliogenesis GO:0042063 24 24 0,000 0,07410657 0,09700171 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,07410657 0,09693286 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,07410657 0,09686412 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,07410657 0,09679547 ! T cell differentiation GO:0030217 24 24 0,000 0,07410657 0,09672691 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,07410657 0,09665846 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,07410657 0,0965901 ! ovulation cycle GO:0042698 24 24 0,000 0,07410657 0,09652184 ! fertilization GO:0009566 25 24 0,000 0,07410657 0,09645367 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,07410657 0,09638561 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,07410657 0,09631763 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,07410657 0,09624976 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,07707764 0,10003809 ! negative regulation of secretion GO:0051048 26 25 0,000 0,07707764 0,09996769 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,07707764 0,09989739 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,07707764 0,09982719 ! cellular component disassembly GO:0022411 26 25 0,000 0,07707764 0,09975708 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,07707764 0,09968708 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,07707764 0,09961717 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,07707764 0,09954736 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,07707764 0,09947765 ! excretion GO:0007588 25 25 0,000 0,07707764 0,09940804 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,07707764 0,09933852 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,07707764 0,0992691 ! gastrulation GO:0007369 25 25 0,000 0,07707764 0,09919978 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,07707764 0,09913055 ! regulation of endocytosis GO:0030100 25 25 0,000 0,07707764 0,09906143 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,07707764 0,09899239 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,07707764 0,09892346 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,07707764 0,09885462 ! positive regulation of binding GO:0051099 27 26 0,000 0,08003961 0,10258205 ! positive regulation of defense response GO:0031349 26 26 0,000 0,08003961 0,10251077 ! glycolysis GO:0006096 26 26 0,000 0,08003961 0,10243958 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,08003961 0,10236849 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,08003961 0,1022975 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,08003961 0,10222661 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,08003961 0,10215581 ! cellular defense response GO:0006968 26 26 0,000 0,08003961 0,10208512 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,08003961 0,10201452 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,08003961 0,10194402 ! double-strand break repair GO:0006302 27 26 0,000 0,08003961 0,10187361 ! regulation of protein secretion GO:0050708 26 26 0,000 0,08003961 0,10180331 ! germ cell development GO:0007281 27 26 0,000 0,08003961 0,1017331 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,08003961 0,10166299 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,08003961 0,10159297 ! synapse organization GO:0050808 26 26 0,000 0,08003961 0,10152305 ! chloride transport GO:0006821 27 27 0,000 0,0829925 0,10519613 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,0829925 0,10512383 ! learning or memory GO:0007611 28 27 0,000 0,0829925 0,10505163 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,0829925 0,10497953 ! peptide metabolic process GO:0006518 29 27 0,000 0,0829925 0,10490753 ! activation of caspase activity GO:0006919 27 27 0,000 0,0829925 0,10483562 ! mesenchymal cell development GO:0014031 29 27 0,000 0,0829925 0,10476382 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,0829925 0,10469211 ! defense response to bacterium GO:0042742 27 27 0,000 0,0829925 0,1046205 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,0829925 0,10454899 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,0829925 0,10447758 ! cell growth GO:0016049 27 27 0,000 0,0829925 0,10440626 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,08593634 0,10803593 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,08593634 0,10796229 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,08593634 0,10788875 ! carbohydrate transport GO:0008643 28 28 0,000 0,08593634 0,1078153 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,08593634 0,10774196 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,08593634 0,10766871 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,08593634 0,10759557 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,08593634 0,10752253 ! histone modification GO:0016570 28 28 0,000 0,08593634 0,10744958 ! developmental growth GO:0048589 28 28 0,000 0,08593634 0,10737673 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,08593634 0,10730398 ! cartilage development GO:0051216 29 28 0,000 0,08593634 0,10723133 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,08887116 0,11081837 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,08887116 0,11074345 ! leukocyte migration GO:0050900 30 29 0,000 0,08887116 0,11066862 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,08887116 0,11059389 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,08887116 0,11051927 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,08887116 0,11044474 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,08887116 0,11037032 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,08887116 0,110296 ! tRNA processing GO:0008033 29 29 0,000 0,08887116 0,11022177 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,08887116 0,11014765 ! covalent chromatin modification GO:0016569 29 29 0,000 0,08887116 0,11007363 ! adult behavior GO:0030534 30 29 0,000 0,08887116 0,1099997 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,08887116 0,10992588 ! transition metal ion transport GO:0000041 31 30 0,000 0,09179699 0,11346871 ! RNA catabolic process GO:0006401 30 30 0,000 0,09179699 0,11339266 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,09179699 0,11331671 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,09179699 0,11324087 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,09179699 0,11316512 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,09179699 0,11308947 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,09179699 0,11301393 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,09179699 0,11293849 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,09179699 0,11286314 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,09179699 0,1127879 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,09179699 0,11271276 ! response to temperature stimulus GO:0009266 30 30 0,000 0,09179699 0,11263772 ! regulation of ossification GO:0030278 30 30 0,000 0,09179699 0,11256278 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,09179699 0,11248793 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,09179699 0,11241319 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,09179699 0,11233855 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,09179699 0,112264 ! vesicle organization GO:0016050 30 30 0,000 0,09179699 0,11218956 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,09179699 0,11211521 ! establishment of organelle localization GO:0051656 31 30 0,000 0,09179699 0,11204096 ! regulation of translational initiation GO:0006446 31 31 0,000 0,09471385 0,11552457 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,09471385 0,11544816 ! membrane fusion GO:0006944 31 31 0,000 0,09471385 0,11537186 ! B cell activation GO:0042113 31 31 0,000 0,09471385 0,11529565 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,09471385 0,11521955 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,09471385 0,11514355 ! ion transmembrane transport GO:0034220 31 31 0,000 0,09471385 0,11506765 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,09471385 0,11499184 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,09471385 0,11491614 ! digestion GO:0007586 31 31 0,000 0,09471385 0,11484054 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,09471385 0,11476504 ! regulation of heart contraction GO:0008016 31 31 0,000 0,09471385 0,11468963 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,09471385 0,11461433 ! camera-type eye development GO:0043010 31 31 0,000 0,09471385 0,11453912 ! extracellular matrix organization GO:0030198 31 31 0,000 0,09471385 0,11446401 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,09471385 0,114389 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,09471385 0,11431409 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,09471385 0,11423928 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,09471385 0,11416457 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,09762176 0,11759275 ! cell redox homeostasis GO:0045454 32 32 0,000 0,09762176 0,11751594 ! muscle fiber development GO:0048747 32 32 0,000 0,09762176 0,11743923 ! glucose catabolic process GO:0006007 32 32 0,000 0,09762176 0,11736262 ! lipid modification GO:0030258 32 32 0,000 0,09762176 0,11728612 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,09762176 0,11720971 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,09762176 0,1171334 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,09762176 0,11705719 ! cell maturation GO:0048469 32 32 0,000 0,09762176 0,11698108 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,09762176 0,11690507 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,09762176 0,11682916 ! nuclear export GO:0051168 32 32 0,000 0,09762176 0,11675334 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,09762176 0,11667763 ! kidney development GO:0001822 32 32 0,000 0,09762176 0,11660201 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,09762176 0,11652649 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,09762176 0,11645107 ! negative regulation of cell size GO:0045792 33 33 0,000 0,10052076 0,11983166 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,10052076 0,1197542 ! amino acid transport GO:0006865 33 33 0,000 0,10052076 0,11967684 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,10052076 0,11959958 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,10052076 0,11952242 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,10052076 0,11944536 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,10052076 0,1193684 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,10052076 0,11929153 ! regulation of actin filament length GO:0030832 34 34 0,000 0,10341086 0,12264235 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,10341086 0,12256348 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,10341086 0,12248471 ! response to metal ion GO:0010038 34 34 0,000 0,10341086 0,12240605 ! ear development GO:0043583 34 34 0,000 0,10341086 0,12232748 ! muscle cell differentiation GO:0042692 35 34 0,000 0,10341086 0,12224901 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,10341086 0,12217065 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,10341086 0,12209239 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,10341086 0,12201422 ! secondary metabolic process GO:0019748 34 34 0,000 0,10341086 0,12193616 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,10341086 0,12185819 ! detection of stimulus GO:0051606 36 34 0,000 0,10341086 0,12178033 ! acute inflammatory response GO:0002526 35 35 0,000 0,1062921 0,12509345 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,1062921 0,12501362 ! regulation of cellular component size GO:0032535 35 35 0,000 0,1062921 0,12493389 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,1062921 0,12485426 ! mesoderm development GO:0007498 35 35 0,000 0,1062921 0,12477474 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,1062921 0,12469531 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,1062921 0,12461599 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,1062921 0,12453677 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,1062921 0,12445765 ! inorganic anion transport GO:0015698 35 35 0,000 0,1062921 0,12437863 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,1062921 0,12429971 ! regulation of immune effector process GO:0002697 35 35 0,000 0,1062921 0,12422089 ! hydrogen transport GO:0006818 36 36 0,000 0,1091645 0,12749694 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,1091645 0,12741619 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,1091645 0,12733555 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,1091645 0,12725501 ! regulation of mitosis GO:0007088 37 36 0,000 0,1091645 0,12717457 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,1091645 0,12709423 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,1091645 0,127014 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,1091645 0,12693386 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,1091645 0,12685383 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,1091645 0,12677389 ! gonad development GO:0008406 36 36 0,000 0,1091645 0,12669406 ! regulation of lipase activity GO:0060191 36 36 0,000 0,1091645 0,12661433 ! activation of immune response GO:0002253 36 36 0,000 0,1091645 0,1265347 ! coagulation GO:0050817 39 36 0,000 0,1091645 0,12645517 GO:0007596|blood coagulation, ! meiosis GO:0007126 37 37 0,000 0,11202808 0,1296908 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,11202808 0,12960939 ! lung development GO:0030324 38 37 0,000 0,11202808 0,12952808 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,11202808 0,12944687 ! eye development GO:0001654 37 37 0,000 0,11202808 0,12936576 ! negative regulation of growth GO:0045926 37 37 0,000 0,11202808 0,12928476 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,11202808 0,12920385 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,11202808 0,12912305 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,11202808 0,12904235 ! adaptive immune response GO:0002250 37 37 0,000 0,11202808 0,12896175 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,11488288 0,13216551 ! neurotransmitter transport GO:0006836 40 38 0,000 0,11488288 0,13208306 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,11488288 0,13200072 ! exocytosis GO:0006887 40 38 0,000 0,11488288 0,13191847 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,11488288 0,13183633 ! chromosome segregation GO:0007059 38 38 0,000 0,11488288 0,13175429 ! urogenital system development GO:0001655 38 38 0,000 0,11488288 0,13167236 ! hexose catabolic process GO:0019320 38 38 0,000 0,11488288 0,13159052 ! RNA elongation GO:0006354 38 38 0,000 0,11488288 0,13150879 ! meiotic cell cycle GO:0051321 38 38 0,000 0,11488288 0,13142716 ! axon guidance GO:0007411 39 38 0,000 0,11488288 0,13134563 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,11488288 0,1312642 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,11488288 0,13118287 ! hemostasis GO:0007599 42 39 0,000 0,11772892 0,13434947 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,11772892 0,13426633 ! respiratory tube development GO:0030323 40 39 0,000 0,11772892 0,1341833 ! response to unfolded protein GO:0006986 39 39 0,000 0,11772892 0,13410037 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,11772892 0,13401754 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,11772892 0,13393481 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,11772892 0,13385219 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,11772892 0,13376966 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,11772892 0,13368724 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,11772892 0,13360492 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,11772892 0,1335227 ! respiratory system development GO:0060541 40 39 0,000 0,11772892 0,13344059 ! developmental maturation GO:0021700 39 39 0,000 0,11772892 0,13335857 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,11772892 0,13327666 ! limb development GO:0060173 39 39 0,000 0,11772892 0,13319484 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,12056622 0,13632119 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,12056622 0,13623761 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,12056622 0,13615413 ! organelle localization GO:0051640 41 40 0,000 0,12056622 0,13607075 ! amine catabolic process GO:0009310 42 41 0,000 0,1233948 0,13917786 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,1233948 0,13909274 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,1233948 0,13900772 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,1233948 0,1389228 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,1233948 0,13883799 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,1233948 0,13875328 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,12621471 0,14183763 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,12621471 0,14175119 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,12621471 0,14166486 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,12621471 0,14157864 ! protein ubiquitination GO:0016567 43 42 0,000 0,12621471 0,14149252 ! response to protein stimulus GO:0051789 42 42 0,000 0,12621471 0,14140651 ! forebrain development GO:0030900 43 42 0,000 0,12621471 0,1413206 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,12621471 0,14123479 ! reproductive structure development GO:0048608 43 43 0,000 0,12902595 0,14429298 ! mitochondrion organization GO:0007005 44 43 0,000 0,12902595 0,14420547 ! alcohol catabolic process GO:0046164 43 43 0,000 0,12902595 0,14411808 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,12902595 0,14403078 ! humoral immune response GO:0006959 44 44 0,000 0,13182856 0,14707024 ! mRNA transport GO:0051028 44 44 0,000 0,13182856 0,14698127 ! protein import into nucleus GO:0006606 44 44 0,000 0,13182856 0,1468924 ! vitamin metabolic process GO:0006766 44 44 0,000 0,13182856 0,14680364 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,13182856 0,146715 ! amine biosynthetic process GO:0009309 46 45 0,000 0,13462256 0,14973408 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,13462256 0,14964377 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,13462256 0,14955357 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,13462256 0,14946348 ! nuclear import GO:0051170 45 45 0,000 0,13462256 0,14937349 ! protein processing GO:0016485 45 45 0,000 0,13462256 0,14928362 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,13740797 0,15228075 ! tube morphogenesis GO:0035239 47 46 0,000 0,13740797 0,15218924 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,13740797 0,15209783 ! regulation of membrane potential GO:0042391 46 46 0,000 0,13740797 0,15200654 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,14018482 0,15498538 ! regulation of blood pressure GO:0008217 48 47 0,000 0,14018482 0,15489246 ! sex differentiation GO:0007548 47 47 0,000 0,14018482 0,15479966 ! amine transport GO:0015837 47 47 0,000 0,14018482 0,15470696 ! rhythmic process GO:0048511 47 47 0,000 0,14018482 0,15461438 ! calcium ion transport GO:0006816 48 48 0,000 0,14295314 0,15757335 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,14295314 0,15747917 ! protein localization in nucleus GO:0034504 48 48 0,000 0,14295314 0,15738509 ! DNA recombination GO:0006310 48 48 0,000 0,14295314 0,15729113 ! leukocyte differentiation GO:0002521 50 49 0,000 0,14571296 0,16023209 ! ossification GO:0001503 50 49 0,000 0,14571296 0,16013654 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,14571296 0,16004111 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,14571296 0,15994579 ! divalent metal ion transport GO:0070838 49 49 0,000 0,14571296 0,15985058 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,14571296 0,15975549 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,14571296 0,15966051 ! response to bacterium GO:0009617 50 49 0,000 0,14571296 0,15956564 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,14571296 0,15947089 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,14571296 0,15937625 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,14846428 0,16228925 ! chromatin assembly GO:0031497 50 50 0,000 0,14846428 0,16219305 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,14846428 0,16209696 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,14846428 0,16200099 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,14846428 0,16190513 ! transcription initiation GO:0006352 50 50 0,000 0,14846428 0,16180939 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,14846428 0,16171376 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,15120715 0,16460412 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,15120715 0,16450695 ! positive regulation of immune response GO:0050778 51 51 0,000 0,15120715 0,1644099 ! rRNA metabolic process GO:0016072 51 51 0,000 0,15120715 0,16431296 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,15120715 0,16421613 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,15120715 0,16411942 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,15120715 0,16402282 ! protein maturation GO:0051604 51 51 0,000 0,15120715 0,16392634 ! RNA localization GO:0006403 52 52 0,000 0,15394158 0,16679267 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,15394158 0,16669468 ! cell fate commitment GO:0045165 52 52 0,000 0,15394158 0,16659679 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,15394158 0,16649903 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,15394158 0,16640137 ! sodium ion transport GO:0006814 53 53 0,000 0,15666761 0,16924877 ! tRNA metabolic process GO:0006399 53 53 0,000 0,15666761 0,16914962 ! response to hypoxia GO:0001666 53 53 0,000 0,15666761 0,16905059 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,15666761 0,16895167 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,15666761 0,16885287 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,15666761 0,16875418 ! regulation of T cell activation GO:0050863 53 53 0,000 0,15666761 0,16865561 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,15938524 0,17148103 ! response to oxygen levels GO:0070482 55 54 0,000 0,15938524 0,17138098 ! response to virus GO:0009615 54 54 0,000 0,15938524 0,17128105 ! hormone metabolic process GO:0042445 55 54 0,000 0,15938524 0,17118124 ! sulfur metabolic process GO:0006790 55 54 0,000 0,15938524 0,17108154 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,15938524 0,17098196 ! nucleosome organization GO:0034728 55 55 0,000 0,16209452 0,1737872 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,16209452 0,17368616 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,16209452 0,17358524 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,16209452 0,17348444 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,16209452 0,17338375 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,16479546 0,17617056 ! extracellular structure organization GO:0043062 56 56 0,000 0,16479546 0,17606843 ! ATP metabolic process GO:0046034 57 57 0,000 0,16748809 0,17884157 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,16748809 0,17873802 ! innate immune response GO:0045087 58 58 0,000 0,17017243 0,18149757 ! dephosphorylation GO:0016311 60 59 0,000 0,17284851 0,18424512 ! carboxylic acid transport GO:0046942 59 59 0,000 0,17284851 0,18413862 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,17284851 0,18403224 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,17284851 0,18392598 ! protein localization in organelle GO:0033365 59 59 0,000 0,17284851 0,18381985 ! immune effector process GO:0002252 59 59 0,000 0,17284851 0,18371384 ! potassium ion transport GO:0006813 60 60 0,000 0,17551635 0,18644186 ! protein polymerization GO:0051258 65 60 0,000 0,17551635 0,18633447 ! cellular respiration GO:0045333 62 61 0,000 0,17817598 0,18904912 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,17817598 0,18894035 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,17817598 0,1888317 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,17817598 0,18872317 ! lipid transport GO:0006869 62 62 0,000 0,18082741 0,19142155 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,18082741 0,19131166 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,18082741 0,1912019 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,18082741 0,19109227 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,18082741 0,19098276 ! protein import GO:0017038 62 62 0,000 0,18082741 0,19087338 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,18082741 0,19076412 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,18082741 0,19065499 ! regulation of secretion GO:0051046 65 63 0,000 0,18347068 0,19333131 ! glucose metabolic process GO:0006006 63 63 0,000 0,18347068 0,19322083 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,18347068 0,19311048 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,18347068 0,19300026 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,1861058 0,19566058 ! angiogenesis GO:0001525 65 64 0,000 0,1861058 0,19554903 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,1861058 0,1954376 ! anion transport GO:0006820 65 65 0,000 0,18873281 0,19808346 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,18873281 0,19797072 ! regulation of hormone levels GO:0010817 66 65 0,000 0,18873281 0,19785811 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,19135172 0,20048961 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,19135172 0,20037569 ! DNA packaging GO:0006323 66 66 0,000 0,19135172 0,20026191 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,19396256 0,20287911 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,19396256 0,20276404 ! muscle contraction GO:0006936 67 67 0,000 0,19396256 0,20264909 ! striated muscle tissue development GO:0014706 69 67 0,000 0,19396256 0,20253427 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,19396256 0,20241959 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,19396256 0,20230503 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,19656535 0,20490381 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,19656535 0,20478798 ! regulation of cell size GO:0008361 68 68 0,000 0,19656535 0,20467228 ! regulation of translation GO:0006417 69 69 0,000 0,19916012 0,20725697 ! response to nutrient levels GO:0031667 69 69 0,000 0,19916012 0,20714001 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,19916012 0,20702318 ! cell part morphogenesis GO:0032990 75 70 0,000 0,20174689 0,20959386 ! wound healing GO:0042060 74 70 0,000 0,20174689 0,20947578 ! growth GO:0040007 70 70 0,000 0,20174689 0,20935783 ! muscle tissue development GO:0060537 72 70 0,000 0,20174689 0,20924002 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,20174689 0,20912234 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,20432568 0,21167635 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,20432568 0,21155743 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,20432568 0,21143864 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,20432568 0,21131999 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,20432568 0,21120147 ! regulation of cell activation GO:0050865 71 71 0,000 0,20432568 0,21108309 ! secretion by cell GO:0032940 75 72 0,000 0,20689652 0,2136192 ! muscle system process GO:0003012 72 72 0,000 0,20689652 0,2134996 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,20689652 0,21338012 ! sensory organ development GO:0007423 72 72 0,000 0,20689652 0,21326078 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,20689652 0,21314158 ! regulation of cytokine production GO:0001817 72 72 0,000 0,20689652 0,2130225 ! electron transport chain GO:0022900 75 74 0,000 0,21201442 0,21817006 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,21201442 0,21804832 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,21456154 0,22054485 ! response to oxidative stress GO:0006979 76 75 0,000 0,21456154 0,22042192 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,21456154 0,22029912 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,2171008 0,22278217 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,2171008 0,22265819 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,21963222 0,22512913 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,21963222 0,22500399 ! regulation of protein modification process GO:0031399 79 78 0,000 0,22215583 0,22746288 ! metal ion homeostasis GO:0055065 78 78 0,000 0,22215583 0,22733658 ! regulation of immune response GO:0050776 78 78 0,000 0,22215583 0,22721043 ! nuclear transport GO:0051169 79 79 0,000 0,22467164 0,22965604 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,22717969 0,232091 ! neuron projection development GO:0031175 85 80 0,000 0,22717969 0,23196242 ! tube development GO:0035295 83 81 0,000 0,22967999 0,2343855 ! lymphocyte activation GO:0046649 82 81 0,000 0,22967999 0,23425579 ! lipid catabolic process GO:0016042 82 81 0,000 0,22967999 0,23412623 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,23465744 0,23906781 ! ncRNA processing GO:0034470 83 83 0,000 0,23465744 0,23893573 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,23465744 0,23880379 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,23713465 0,24119159 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,23960419 0,24356896 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,23960419 0,24343469 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,23960419 0,24330057 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,24206611 0,24566511 ! hexose metabolic process GO:0019318 87 86 0,000 0,24206611 0,2455299 ! male gamete generation GO:0048232 90 88 0,000 0,24696713 0,25036327 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,24696713 0,25022563 ! chemotaxis GO:0006935 90 89 0,000 0,24940628 0,25255812 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,24940628 0,25241943 ! brain development GO:0007420 91 90 0,000 0,25183789 0,25474052 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,25426198 0,25705147 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,25426198 0,25691054 ! visual perception GO:0007601 93 92 0,000 0,25667857 0,2592102 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,25667857 0,25906824 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,25667857 0,25892644 ! tissue morphogenesis GO:0048729 94 93 0,000 0,25908769 0,26121368 ! regulation of response to stress GO:0080134 97 94 0,000 0,26148935 0,26349091 ! blood vessel development GO:0001568 95 94 0,000 0,26148935 0,26334692 ! epidermis development GO:0008544 94 94 0,000 0,26148935 0,26320309 ! cofactor metabolic process GO:0051186 95 94 0,000 0,26148935 0,26305942 ! regulation of cell growth GO:0001558 97 96 0,000 0,26627039 0,26772304 ! vasculature development GO:0001944 97 96 0,000 0,26627039 0,26757706 ! endocytosis GO:0006897 99 98 0,000 0,27102189 0,27220345 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,27102189 0,27205519 ! blood circulation GO:0008015 99 98 0,000 0,27102189 0,2719071 GO:0003013|circulatory system process, ! anti-apoptosis GO:0006916 100 99 0,000 0,2733866 0,27413031 ! ectoderm development GO:0007398 99 99 0,000 0,2733866 0,27398125 ! muscle organ development GO:0007517 102 100 0,000 0,275744 0,27619358 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,275744 0,27604356 ! response to other organism GO:0051707 101 100 0,000 0,275744 0,2758937 ! hemopoiesis GO:0030097 104 100 0,000 0,275744 0,275744