pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6622-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 3,000 2,178E-07 5,01E-04 ! positive regulation of intracellular transport GO:0032388 29 19 3,000 3,531E-07 4,06E-04 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 3,000 3,531E-07 2,707E-04 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 3,000 1,339E-06 7,701E-04 ! regulation of microtubule-based process GO:0032886 58 30 3,000 2,432E-06 1,119E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 2,000 3,677E-06 1,41E-03 ! regulation of intracellular protein transport GO:0033157 59 35 3,000 4,591E-06 1,509E-03 ! positive regulation of protein transport GO:0051222 55 40 3,000 7,919E-06 2,277E-03 ! positive regulation of protein import into nucleus GO:0042307 23 13 2,000 8,704E-06 2,224E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 9,653E-06 2,22E-03 ! negative regulation of microtubule depolymerization GO:0007026 31 14 2,000 1,105E-05 2,311E-03 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 2,000 1,378E-05 2,642E-03 ! calcium ion transport GO:0006816 167 99 4,000 1,598E-05 2,828E-03 ! divalent metal ion transport GO:0070838 171 100 4,000 1,678E-05 2,757E-03 ! regulation of intracellular transport GO:0032386 78 49 3,000 1,797E-05 2,756E-03 ! phosphatidylinositol metabolic process GO:0046488 22 17 2,000 2,051E-05 2,948E-03 ! calcium-independent cell-cell adhesion GO:0016338 21 19 2,000 2,909E-05 3,936E-03 ! phosphoinositide metabolic process GO:0030384 87 60 3,000 4,029E-05 5,149E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 3,000 4,029E-05 4,878E-03 ! negative regulation of ligase activity GO:0051352 91 61 3,000 4,302E-05 4,947E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 3,000 4,302E-05 4,712E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 3,000 4,588E-05 4,796E-03 ! regulation of transcription factor import into nucleus GO:0042990 46 23 2,000 5,269E-05 5,269E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 3,000 5,528E-05 5,298E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 3,000 5,528E-05 5,086E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 6,008E-05 5,315E-03 ! positive regulation of ligase activity GO:0051351 99 69 3,000 6,992E-05 5,956E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 3,000 7,822E-05 6,425E-03 ! regulation of ligase activity GO:0051340 114 75 3,000 9,692E-05 7,687E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,002E-04 7,679E-03 ! early endosome to late endosome transport GO:0045022 11 5 1,000 1,002E-04 7,431E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,002E-04 7,199E-03 ! regulation of protein transport GO:0051223 114 76 3,000 1,021E-04 7,113E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of protein import into nucleus GO:0042306 53 29 2,000 1,072E-04 7,254E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 3,000 1,246E-04 8,19E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of protein export from nucleus GO:0046825 6 6 1,000 1,499E-04 9,579E-03 ! ER overload response GO:0006983 7 6 1,000 1,499E-04 9,32E-03 ! male sex determination GO:0030238 9 6 1,000 1,499E-04 9,075E-03 ! midbrain development GO:0030901 6 6 1,000 1,499E-04 8,842E-03 ! regulation of protein localization GO:0032880 132 85 3,000 1,577E-04 9,066E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 1,736E-04 9,74E-03 ! carbohydrate phosphorylation GO:0046835 8 7 1,000 2,095E-04 0,0114714 ! microtubule bundle formation GO:0001578 8 7 1,000 2,095E-04 0,01120462 ! protein heterooligomerization GO:0051291 10 7 1,000 2,095E-04 0,01094997 ! glycerophospholipid metabolic process GO:0006650 130 92 3,000 2,14E-04 0,01093735 ! regulation of cytoskeleton organization GO:0051493 154 93 3,000 2,231E-04 0,01115397 ! negative regulation of protein complex disassembly GO:0043242 67 39 2,000 2,622E-04 0,01283055 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 2,787E-04 0,01335576 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 2,787E-04 0,0130832 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 2,787E-04 0,01282153 ! regulation of embryonic development GO:0045995 16 8 1,000 2,787E-04 0,01257013 ! response to insulin stimulus GO:0032868 63 43 2,000 3,509E-04 0,0155186 ! regulation of developmental growth GO:0048638 13 9 1,000 3,576E-04 0,01551974 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 3,576E-04 0,01523234 ! regulation of glycolysis GO:0006110 15 9 1,000 3,576E-04 0,01495538 ! receptor clustering GO:0043113 15 9 1,000 3,576E-04 0,01468832 ! postreplication repair GO:0006301 11 9 1,000 3,576E-04 0,01443063 ! regulation of RNA splicing GO:0043484 14 9 1,000 3,576E-04 0,01418183 ! regulation of protein complex disassembly GO:0043244 77 46 2,000 4,286E-04 0,01670983 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 4,461E-04 0,01710114 GO:0043470|regulation of carbohydrate catabolic process, ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 4,461E-04 0,01682079 ! integrin-mediated signaling pathway GO:0007229 81 49 2,000 5,167E-04 0,01916869 ! virus-host interaction GO:0019048 17 11 1,000 5,441E-04 0,01986516 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 5,441E-04 0,01955477 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 5,441E-04 0,01925393 ! negative regulation of cytoskeleton organization GO:0051494 84 50 2,000 5,485E-04 0,01911298 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 6,516E-04 0,02236894 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 6,516E-04 0,02203999 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! intermediate filament cytoskeleton organization GO:0045104 23 13 1,000 7,685E-04 0,02561701 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 8,059E-04 0,02647944 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 8,948E-04 0,02898496 ! inositol metabolic process GO:0006020 20 14 1,000 8,948E-04 0,02858239 ! intermediate filament-based process GO:0045103 24 14 1,000 8,948E-04 0,02819085 ! axon cargo transport GO:0008088 27 14 1,000 8,948E-04 0,0278099 ! lipid phosphorylation GO:0046834 23 15 1,000 1,03E-03 0,03159546 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 1,03E-03 0,03117973 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,175E-03 0,03509897 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,175E-03 0,03464898 ! protein oligomerization GO:0051259 100 65 2,000 1,181E-03 0,03439756 ! signal complex assembly GO:0007172 29 17 1,000 1,329E-03 0,03820851 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 1,329E-03 0,0377368 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 1,329E-03 0,0372766 ! peptidyl-serine modification GO:0018209 27 17 1,000 1,329E-03 0,03682748 ! regulation of catabolic process GO:0009894 106 70 2,000 1,464E-03 0,0400856 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,492E-03 0,04037302 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 1,492E-03 0,03990357 ! negative regulation of organelle organization GO:0010639 115 72 2,000 1,588E-03 0,04197768 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 1,664E-03 0,04349506 GO:0010675|regulation of cellular carbohydrate metabolic process, ! sex determination GO:0007530 29 19 1,000 1,664E-03 0,04300635 ! protein stabilization GO:0050821 26 19 1,000 1,664E-03 0,04252851 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 1,718E-03 0,04342422 ! microtubule-based transport GO:0010970 37 20 1,000 1,845E-03 0,04613178 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 1,845E-03 0,04563574 ! dendrite development GO:0016358 35 21 1,000 2,035E-03 0,04980054 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,035E-03 0,04927632 ! protein tetramerization GO:0051262 39 22 1,000 2,234E-03 0,05352932 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 2,442E-03 0,05790396 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 2,442E-03 0,0573131 ! interaction with host GO:0051701 37 23 1,000 2,442E-03 0,05673418 ! negative regulation of catabolic process GO:0009895 34 23 1,000 2,442E-03 0,05616684 ! liver development GO:0001889 40 23 1,000 2,442E-03 0,05561073 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 2,469E-03 0,05567395 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 2,659E-03 0,05936631 ! receptor metabolic process GO:0043112 37 24 1,000 2,659E-03 0,05879548 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 2,884E-03 0,06316974 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 3,295E-03 0,07149442 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 3,36E-03 0,07223021 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 1,000 3,36E-03 0,07156142 ! BMP signaling pathway GO:0030509 40 28 1,000 3,611E-03 0,0762027 ! neural tube formation GO:0001841 41 28 1,000 3,611E-03 0,07550995 ! positive regulation of catabolic process GO:0009896 40 28 1,000 3,611E-03 0,07482968 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 3,929E-03 0,08068805 ! hindbrain development GO:0030902 45 30 1,000 4,139E-03 0,08424332 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 4,139E-03 0,08350435 ! maintenance of protein location in cell GO:0032507 60 31 1,000 4,415E-03 0,08830594 ! regulation of protein stability GO:0031647 48 32 1,000 4,7E-03 0,09318988 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 4,7E-03 0,09239339 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 4,993E-03 0,09732121 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 4,993E-03 0,09650338 ! carbohydrate homeostasis GO:0033500 39 33 1,000 4,993E-03 0,09569919 GO:0042593|glucose homeostasis, ! negative regulation of DNA binding GO:0043392 54 33 1,000 4,993E-03 0,09490829 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 5,294E-03 0,09980891 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 5,294E-03 0,09899745 ! polyol metabolic process GO:0019751 44 34 1,000 5,294E-03 0,09819909 ! maintenance of protein location GO:0045185 65 35 1,000 5,604E-03 0,10310604 ! glycogen metabolic process GO:0005977 48 35 1,000 5,604E-03 0,10228774 ! protein homooligomerization GO:0051260 52 35 1,000 5,604E-03 0,10148232 ! negative regulation of binding GO:0051100 58 36 1,000 5,921E-03 0,10639441 ! neural tube development GO:0021915 50 36 1,000 5,921E-03 0,10556965 ! glucan metabolic process GO:0044042 49 36 1,000 5,921E-03 0,10475758 GO:0006073|cellular glucan metabolic process, ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 6,58E-03 0,11553007 ! maintenance of location in cell GO:0051651 69 38 1,000 6,58E-03 0,11465484 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 6,922E-03 0,11969865 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 7,271E-03 0,12480281 ! energy reserve metabolic process GO:0006112 59 41 1,000 7,628E-03 0,12996509 ! endosome transport GO:0016197 71 41 1,000 7,628E-03 0,12900947 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 8,366E-03 0,14045544 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 8,366E-03 0,13943764 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 9,135E-03 0,15115318 ! response to UV GO:0009411 75 46 1,000 9,531E-03 0,15657495 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,0103447 0,16874336 ! heart morphogenesis GO:0003007 65 48 1,000 0,0103447 0,16755502 ! regulation of DNA replication GO:0006275 75 48 1,000 0,0103447 0,16638331 ! maintenance of location GO:0051235 84 49 1,000 0,01076291 0,17190764 ! lipid modification GO:0030258 73 50 1,000 0,01118852 0,17747301 ! positive regulation of growth GO:0045927 67 50 1,000 0,01118852 0,17625744 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,01162146 0,18183234 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,01162146 0,18060374 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,01389455 0,21447962 ! viral reproductive process GO:0022415 87 58 1,000 0,01485345 0,22775288 ! activation of MAPK activity GO:0000187 84 59 1,000 0,01534335 0,23370662 ! actin filament organization GO:0007015 95 59 1,000 0,01534335 0,23216908 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,01584015 0,23811987 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,015916 0,2377065 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,015916 0,23617291 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,015916 0,23465898 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,015916 0,23316434 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,015916 0,23168862 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,015916 0,23023145 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,015916 0,22879251 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,015916 0,22737144 ! sleep GO:0030431 11 5 0,000 0,015916 0,22596791 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,015916 0,2245816 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,015916 0,2232122 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,015916 0,2218594 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,015916 0,2205229 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,015916 0,2192024 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,015916 0,21789763 ! tongue development GO:0043586 6 5 0,000 0,015916 0,21660829 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,015916 0,21533413 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,015916 0,21407486 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,015916 0,21283024 ! cobalt ion transport GO:0006824 9 5 0,000 0,015916 0,21160001 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,015916 0,21038392 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,015916 0,20918172 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,015916 0,20799319 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,015916 0,20681809 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,015916 0,20565619 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,015916 0,20450727 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,015916 0,20337112 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,015916 0,20224752 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,015916 0,20113627 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,015916 0,20003717 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,015916 0,19895001 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,015916 0,1978746 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,015916 0,19681076 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,015916 0,1957583 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,015916 0,19471703 ! malate metabolic process GO:0006108 7 5 0,000 0,015916 0,19368678 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,015916 0,19266738 ! behavioral response to pain GO:0048266 7 5 0,000 0,015916 0,19165865 ! clathrin coat assembly GO:0048268 11 5 0,000 0,015916 0,19066042 ! phototransduction, visible light GO:0007603 6 5 0,000 0,015916 0,18967255 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,015916 0,18869485 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,015916 0,18772719 ! mating behavior GO:0007617 6 5 0,000 0,015916 0,18676939 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,015916 0,18582133 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,015916 0,18488283 ! rhythmic behavior GO:0007622 12 5 0,000 0,015916 0,18395378 ! copulation GO:0007620 7 5 0,000 0,015916 0,18303401 ! glial cell fate commitment GO:0021781 12 5 0,000 0,015916 0,18212339 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,015916 0,18122179 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,015916 0,18032907 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,015916 0,1794451 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,015916 0,17856976 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,015916 0,17770292 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,015916 0,17684445 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,015916 0,17599424 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,015916 0,17515216 ! response to protozoan GO:0001562 9 5 0,000 0,015916 0,1743181 ! lymph vessel development GO:0001945 7 5 0,000 0,015916 0,17349195 ! endochondral ossification GO:0001958 12 5 0,000 0,015916 0,17267359 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,015916 0,17186292 ! parathyroid gland development GO:0060017 8 5 0,000 0,015916 0,17105982 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,015916 0,17026419 ! anagen GO:0042640 6 5 0,000 0,015916 0,16947593 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,015916 0,16869494 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,015916 0,16792111 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,015916 0,16715434 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,015916 0,16639455 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,015916 0,16564163 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,015916 0,1648955 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,015916 0,16415606 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,015916 0,16342322 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,015916 0,16269689 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,015916 0,161977 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,015916 0,16126344 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,015916 0,16055615 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,015916 0,15985503 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,015916 0,15916001 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,015916 0,158471 ! ovulation GO:0030728 6 5 0,000 0,015916 0,15778794 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,015916 0,15711074 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,015916 0,15643932 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,015916 0,15577362 ! response to pH GO:0009268 9 5 0,000 0,015916 0,15511356 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,015916 0,15445908 ! proline biosynthetic process GO:0006561 6 5 0,000 0,015916 0,15381009 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,015916 0,15316653 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,015916 0,15252834 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,015916 0,15189544 ! polyol catabolic process GO:0046174 7 5 0,000 0,015916 0,15126777 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,015916 0,15064527 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,015916 0,15002787 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,015916 0,14941552 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,015916 0,14880814 ! nerve growth factor processing GO:0032455 7 5 0,000 0,015916 0,14820567 ! urea metabolic process GO:0019627 6 5 0,000 0,015916 0,14760807 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,015916 0,14701527 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,015916 0,14642721 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,015916 0,14584383 ! neutrophil activation GO:0042119 5 5 0,000 0,015916 0,14526508 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,015916 0,14469091 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,015916 0,14412126 ! response to food GO:0032094 5 5 0,000 0,015916 0,14355608 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,015916 0,14299532 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,015916 0,14243892 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,015916 0,14188683 ! forebrain neuron development GO:0021884 7 5 0,000 0,015916 0,141339 ! melanosome organization GO:0032438 7 5 0,000 0,015916 0,14079539 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,015916 0,14025594 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,015916 0,13972062 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,015916 0,13918936 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,015916 0,13866213 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,015916 0,13813887 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,015916 0,13761955 ! nucleoside transport GO:0015858 6 5 0,000 0,015916 0,13710412 ! nucleoside salvage GO:0043174 7 5 0,000 0,015916 0,13659254 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,015916 0,13608476 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,015916 0,13558075 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,015916 0,13508045 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,015916 0,13458383 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,015916 0,13409085 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,015916 0,13360146 ! depyrimidination GO:0045008 8 5 0,000 0,015916 0,13311564 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,015916 0,13263334 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,015916 0,13215452 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,015916 0,13167914 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,015916 0,13120717 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,015916 0,13073858 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,015916 0,13027331 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,015916 0,12981135 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,015916 0,12935265 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,015916 0,12889719 ! monocyte differentiation GO:0030224 8 5 0,000 0,015916 0,12844492 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,015916 0,12799581 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,015916 0,12754983 ! centrosome duplication GO:0051298 5 5 0,000 0,015916 0,12710695 ! response to UV-C GO:0010225 6 5 0,000 0,015916 0,12666713 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,015916 0,12623035 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,015916 0,12579657 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,015916 0,12536576 ! regulation of dendrite development GO:0050773 12 5 0,000 0,015916 0,12493789 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,015916 0,12451293 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,015916 0,12409085 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,015916 0,12367163 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,015916 0,12325522 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,015916 0,12284162 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,015916 0,12243077 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,015916 0,12202267 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,015916 0,12161728 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,015916 0,12121457 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,015916 0,12081453 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,015916 0,12041711 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,015916 0,1200223 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,015916 0,11963007 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,015916 0,1192404 ! neural tube patterning GO:0021532 6 5 0,000 0,015916 0,11885325 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,015916 0,11846861 ! histone demethylation GO:0016577 9 5 0,000 0,015916 0,11808646 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,015916 0,11770676 ! regulation of sterol transport GO:0032371 7 5 0,000 0,015916 0,11732949 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,015916 0,11695464 ! enteric nervous system development GO:0048484 8 5 0,000 0,015916 0,11658217 ! establishment of planar polarity GO:0001736 6 5 0,000 0,015916 0,11621207 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,015916 0,11584431 ! muscle cell proliferation GO:0033002 8 5 0,000 0,015916 0,11547887 ! transcription termination GO:0006353 8 5 0,000 0,015916 0,11511573 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,015916 0,11475486 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,015916 0,11439625 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,015916 0,11403988 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,015916 0,11368572 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,015916 0,11333375 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,015916 0,11298395 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,015916 0,11263631 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,015916 0,1122908 ! apical protein localization GO:0045176 6 5 0,000 0,015916 0,1119474 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,015916 0,1116061 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,015916 0,11126687 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,015916 0,1109297 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,015916 0,11059457 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,015916 0,11026145 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,015916 0,10993033 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,015916 0,1096012 ! glial cell migration GO:0008347 10 5 0,000 0,015916 0,10927403 ! determination of adult lifespan GO:0008340 8 5 0,000 0,015916 0,10894881 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,015916 0,10862552 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,015916 0,10830415 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,015916 0,10798466 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,015916 0,10766706 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,015916 0,10735132 ! neural plate development GO:0001840 6 5 0,000 0,015916 0,10703743 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,015916 0,10672537 ! regulation of sensory perception GO:0051931 6 5 0,000 0,015916 0,10641512 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,015916 0,10610667 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,015916 0,1058 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,015916 0,1054951 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,015916 0,10519196 ! sensory cilium assembly GO:0035058 6 5 0,000 0,015916 0,10489055 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,015916 0,10459086 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,015916 0,10429288 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,015916 0,10399659 ! spindle assembly GO:0051225 5 5 0,000 0,015916 0,10370199 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,015916 0,10340904 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,015916 0,10311775 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,015916 0,10282809 ! organ regeneration GO:0031100 7 5 0,000 0,015916 0,10254006 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,015916 0,10225363 ! carnitine metabolic process GO:0009437 5 5 0,000 0,015916 0,10196881 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,015916 0,10168556 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,015916 0,10140388 GO:0055081|anion homeostasis, ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,01737149 0,11037133 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,01737149 0,11006727 ! viral reproduction GO:0016032 92 63 1,000 0,01737149 0,10976489 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,01789542 0,11276567 ! regulation of caspase activity GO:0043281 97 65 1,000 0,01842602 0,11579195 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,01896324 0,11884322 ! tRNA transcription GO:0009304 11 6 0,000 0,01906921 0,11918258 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01906921 0,1188596 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01906921 0,11853835 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01906921 0,11821884 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01906921 0,11790105 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01906921 0,11758496 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01906921 0,11727056 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01906921 0,11695784 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01906921 0,11664679 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01906921 0,11633738 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01906921 0,11602961 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01906921 0,11572346 ! prostate gland development GO:0030850 9 6 0,000 0,01906921 0,11541892 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01906921 0,11511599 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01906921 0,11481464 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01906921 0,11451486 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01906921 0,11421664 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01906921 0,11391998 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01906921 0,11362485 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01906921 0,11333124 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01906921 0,11303915 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01906921 0,11274856 ! neuron adhesion GO:0007158 9 6 0,000 0,01906921 0,11245946 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01906921 0,11217184 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01906921 0,11188569 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01906921 0,111601 ! signal peptide processing GO:0006465 8 6 0,000 0,01906921 0,11131774 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01906921 0,11103593 ! mRNA stabilization GO:0048255 15 6 0,000 0,01906921 0,11075553 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01906921 0,11047655 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01906921 0,11019897 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01906921 0,10992279 ! opsonization GO:0008228 8 6 0,000 0,01906921 0,10964798 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01906921 0,10937454 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01906921 0,10910247 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01906921 0,10883174 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01906921 0,10856235 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01906921 0,1082943 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01906921 0,10802756 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01906921 0,10776214 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01906921 0,10749802 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01906921 0,10723519 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01906921 0,10697364 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01906921 0,10671336 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01906921 0,10645435 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01906921 0,10619659 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01906921 0,10594008 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01906921 0,1056848 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01906921 0,10543075 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01906921 0,10517792 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01906921 0,10492629 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01906921 0,10467587 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01906921 0,10442665 ! thymic T cell selection GO:0045061 12 6 0,000 0,01906921 0,1041786 ! protein lipoylation GO:0009249 10 6 0,000 0,01906921 0,10393173 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01906921 0,10368603 ! pigment granule organization GO:0048753 11 6 0,000 0,01906921 0,10344149 ! drug transport GO:0015893 6 6 0,000 0,01906921 0,1031981 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01906921 0,10295585 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01906921 0,10271473 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01906921 0,10247475 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01906921 0,10223588 ! histidine metabolic process GO:0006547 6 6 0,000 0,01906921 0,10199812 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01906921 0,10176146 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01906921 0,10152591 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01906921 0,10129143 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01906921 0,10105804 ! adenohypophysis development GO:0021984 10 6 0,000 0,01906921 0,10082573 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01906921 0,10059448 ! hyperosmotic response GO:0006972 8 6 0,000 0,01906921 0,10036428 ! microtubule nucleation GO:0007020 10 6 0,000 0,01906921 0,10013514 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01906921 0,09990704 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01906921 0,09967998 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01906921 0,09945395 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01906921 0,09922894 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01906921 0,09900495 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01906921 0,09878196 ! response to dietary excess GO:0002021 7 6 0,000 0,01906921 0,09855998 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01906921 0,09833899 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01906921 0,098119 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01906921 0,09789998 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01906921 0,09768194 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01906921 0,09746487 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01906921 0,09724876 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01906921 0,09703361 ! neuron apoptosis GO:0051402 8 6 0,000 0,01906921 0,09681941 ! organic alcohol transport GO:0015850 9 6 0,000 0,01906921 0,09660615 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01906921 0,09639383 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01906921 0,09618244 ! carnitine transport GO:0015879 8 6 0,000 0,01906921 0,09597197 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01906921 0,09576243 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01906921 0,09555379 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01906921 0,09534607 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01906921 0,09513924 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01906921 0,09493331 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01906921 0,09472827 ! parturition GO:0007567 12 6 0,000 0,01906921 0,09452412 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01906921 0,09432084 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01906921 0,09411844 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01906921 0,0939169 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01906921 0,09371622 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01906921 0,0935164 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01906921 0,09331743 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01906921 0,0931193 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01906921 0,09292202 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01906921 0,09272556 ! macrophage differentiation GO:0030225 10 6 0,000 0,01906921 0,09252994 ! astrocyte development GO:0014002 14 6 0,000 0,01906921 0,09233514 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01906921 0,09214116 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01906921 0,09194799 ! interaction with symbiont GO:0051702 8 6 0,000 0,01906921 0,09175563 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01906921 0,09156407 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01906921 0,09137332 ! eating behavior GO:0042755 6 6 0,000 0,01906921 0,09118335 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01906921 0,09099417 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01906921 0,09080578 ! response to copper ion GO:0046688 9 6 0,000 0,01906921 0,09061816 ! DNA topological change GO:0006265 8 6 0,000 0,01906921 0,09043132 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01906921 0,09024525 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01906921 0,09005994 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01906921 0,08987539 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01906921 0,0896916 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01906921 0,08950855 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01906921 0,08932626 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01906921 0,0891447 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01906921 0,08896388 ! gas homeostasis GO:0033483 11 6 0,000 0,01906921 0,08878379 ! hair follicle maturation GO:0048820 7 6 0,000 0,01906921 0,08860443 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01906921 0,08842579 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01906921 0,08824787 ! Schwann cell development GO:0014044 14 6 0,000 0,01906921 0,08807067 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01906921 0,08789417 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01906921 0,08771838 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01906921 0,0875433 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01906921 0,08736891 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01906921 0,08719521 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01906921 0,0870222 ! histone ubiquitination GO:0016574 7 6 0,000 0,01906921 0,08684988 ! regulation of meiosis GO:0040020 10 6 0,000 0,01906921 0,08667824 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01906921 0,08650728 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01906921 0,08633699 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01906921 0,08616737 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01906921 0,08599841 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01906921 0,08583012 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01906921 0,08566248 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01906921 0,0854955 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01906921 0,08532917 ! receptor internalization GO:0031623 9 6 0,000 0,01906921 0,08516348 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01906921 0,08499843 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01906921 0,08483403 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01906921 0,08467025 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01906921 0,08450711 ! protein deubiquitination GO:0016579 8 6 0,000 0,01906921 0,0843446 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01906921 0,08418271 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01906921 0,08402144 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01906921 0,08386079 ! axonal fasciculation GO:0007413 9 6 0,000 0,01906921 0,08370075 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01906921 0,08354132 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01906921 0,08338249 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01906921 0,08322427 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01906921 0,08306665 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01906921 0,08290962 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01906921 0,08275319 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01906921 0,08259735 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01906921 0,08244209 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01906921 0,08228741 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01906921 0,08213332 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01906921 0,0819798 ! adult feeding behavior GO:0008343 6 6 0,000 0,01906921 0,08182685 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01906921 0,08167447 ! blastocyst growth GO:0001832 15 6 0,000 0,01906921 0,08152266 ! pigment granule transport GO:0051904 12 6 0,000 0,01906921 0,08137141 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01906921 0,08122072 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01906921 0,08107059 ! catecholamine transport GO:0051937 7 6 0,000 0,01906921 0,08092102 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01906921 0,08077199 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01906921 0,08062351 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01906921 0,08047558 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01906921 0,08032819 ! protein prenylation GO:0018342 10 6 0,000 0,01906921 0,08018134 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01906921 0,08003502 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01906921 0,07988924 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01906921 0,07974398 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01906921 0,07959926 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01906921 0,07945506 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,01950704 0,08113235 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,02117741 0,08792064 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,0222125 0,09205181 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0222125 0,09188625 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0222125 0,09172129 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0222125 0,09155691 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0222125 0,09139312 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0222125 0,09122992 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0222125 0,0910673 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0222125 0,09090526 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0222125 0,0907438 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0222125 0,0905829 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0222125 0,09042258 ! reproductive behavior GO:0019098 12 7 0,000 0,0222125 0,09026282 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0222125 0,09010363 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,0222125 0,08994499 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0222125 0,08978692 ! oligopeptide transport GO:0006857 11 7 0,000 0,0222125 0,0896294 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0222125 0,08947243 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0222125 0,08931601 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0222125 0,08916013 ! RNA methylation GO:0001510 11 7 0,000 0,0222125 0,0890048 ! pericardium development GO:0060039 8 7 0,000 0,0222125 0,08885001 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0222125 0,08869576 ! fibril organization GO:0043206 13 7 0,000 0,0222125 0,08854204 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,0222125 0,08838885 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0222125 0,08823619 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,0222125 0,08808406 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0222125 0,08793246 ! lipoprotein transport GO:0042953 9 7 0,000 0,0222125 0,08778137 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0222125 0,0876308 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0222125 0,08748075 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0222125 0,08733121 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0222125 0,08718218 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0222125 0,08703366 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0222125 0,08688564 ! chemosensory behavior GO:0007635 9 7 0,000 0,0222125 0,08673813 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0222125 0,08659111 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0222125 0,0864446 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0222125 0,08629858 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0222125 0,08615305 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0222125 0,08600801 ! reflex GO:0060004 12 7 0,000 0,0222125 0,08586346 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0222125 0,08571939 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0222125 0,08557581 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0222125 0,0854327 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0222125 0,08529008 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0222125 0,08514793 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0222125 0,08500625 ! spinal cord patterning GO:0021511 7 7 0,000 0,0222125 0,08486504 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0222125 0,08472431 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0222125 0,08458403 ! adrenal gland development GO:0030325 17 7 0,000 0,0222125 0,08444423 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0222125 0,08430488 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0222125 0,08416599 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0222125 0,08402756 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0222125 0,08388958 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0222125 0,08375206 ! endosome organization GO:0007032 10 7 0,000 0,0222125 0,08361499 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0222125 0,08347836 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0222125 0,08334218 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0222125 0,08320644 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0222125 0,08307115 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0222125 0,08293629 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0222125 0,08280187 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0222125 0,08266789 ! galactose metabolic process GO:0006012 10 7 0,000 0,0222125 0,08253434 ! vesicle fusion GO:0006906 15 7 0,000 0,0222125 0,08240122 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0222125 0,08226853 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0222125 0,08213626 ! organ growth GO:0035265 11 7 0,000 0,0222125 0,08200442 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0222125 0,08187301 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0222125 0,08174201 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0222125 0,08161143 ! retinol metabolic process GO:0042572 9 7 0,000 0,0222125 0,08148127 ! behavioral fear response GO:0001662 13 7 0,000 0,0222125 0,08135152 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0222125 0,08122219 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0222125 0,08109326 ! rRNA modification GO:0000154 12 7 0,000 0,0222125 0,08096475 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0222125 0,08083664 ! response to UV-B GO:0010224 11 7 0,000 0,0222125 0,08070894 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0222125 0,08058164 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0222125 0,08045473 ! intermediate filament organization GO:0045109 11 7 0,000 0,0222125 0,08032823 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0222125 0,08020213 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0222125 0,08007642 ! fibrinolysis GO:0042730 9 7 0,000 0,0222125 0,07995111 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0222125 0,07982618 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0222125 0,07970165 ! B cell lineage commitment GO:0002326 17 7 0,000 0,0222125 0,0795775 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0222125 0,07945374 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0222125 0,07933037 ! response to tropane GO:0014073 13 7 0,000 0,0222125 0,07920737 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0222125 0,07908476 ! melanosome localization GO:0032400 10 7 0,000 0,0222125 0,07896253 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0222125 0,07884067 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0222125 0,07871919 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0222125 0,07859809 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0222125 0,07847735 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0222125 0,07835699 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0222125 0,07823699 ! mast cell activation GO:0045576 9 7 0,000 0,0222125 0,07811736 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0222125 0,0779981 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0222125 0,0778792 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0222125 0,07776066 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0222125 0,07764249 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0222125 0,07752467 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0222125 0,07740721 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0222125 0,0772901 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0222125 0,07717335 ! T cell lineage commitment GO:0002360 12 7 0,000 0,0222125 0,07705695 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0222125 0,0769409 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0222125 0,0768252 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0222125 0,07670984 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0222125 0,07659484 ! response to tumor cell GO:0002347 12 7 0,000 0,0222125 0,07648017 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0222125 0,07636585 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0222125 0,07625188 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0222125 0,07613824 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0222125 0,07602494 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0222125 0,07591197 ! diuresis GO:0030146 12 7 0,000 0,0222125 0,07579934 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0222125 0,07568705 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0222125 0,07557508 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0222125 0,07546345 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0222125 0,07535215 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0222125 0,07524117 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0222125 0,07513052 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0222125 0,0750202 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0222125 0,0749102 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0222125 0,07480052 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0222125 0,07469116 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0222125 0,07458213 ! lymph node development GO:0048535 9 7 0,000 0,0222125 0,07447341 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0222125 0,074365 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0222125 0,07425691 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0222125 0,07414914 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0222125 0,07404168 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0222125 0,07393452 ! ATP catabolic process GO:0006200 10 7 0,000 0,0222125 0,07382768 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0222125 0,07372115 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0222125 0,07361492 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0222125 0,073509 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0222125 0,07340339 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0222125 0,07329807 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0222125 0,07319306 ! muscle adaptation GO:0043500 12 7 0,000 0,0222125 0,07308835 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0222125 0,07298394 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0222125 0,07287982 ! retina homeostasis GO:0001895 9 7 0,000 0,0222125 0,07277601 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0222125 0,07267248 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0222125 0,07256926 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0222125 0,07246632 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0222125 0,07236368 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0222125 0,07226132 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0222125 0,07215926 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0222125 0,07205748 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,02232301 0,07231399 ! negative regulation of transport GO:0051051 116 73 1,000 0,02290529 0,07409588 ! tube morphogenesis GO:0035239 118 73 1,000 0,02290529 0,07399181 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,02529652 0,08160167 ! regulation of DNA binding GO:0051101 119 77 1,000 0,02529652 0,08148738 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,0253459 0,08153226 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,0253459 0,08141839 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,0253459 0,08130484 ! axon extension GO:0048675 11 8 0,000 0,0253459 0,0811916 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,0253459 0,08107868 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,0253459 0,08096607 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,0253459 0,08085377 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,0253459 0,08074178 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,0253459 0,08063011 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,0253459 0,08051874 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,0253459 0,08040768 ! phosphate transport GO:0006817 10 8 0,000 0,0253459 0,08029693 ! N-glycan processing GO:0006491 12 8 0,000 0,0253459 0,08018648 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,0253459 0,08007633 ! UTP metabolic process GO:0046051 8 8 0,000 0,0253459 0,07996649 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,0253459 0,07985694 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,0253459 0,0797477 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,0253459 0,07963875 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,0253459 0,07953011 ! succinate metabolic process GO:0006105 14 8 0,000 0,0253459 0,07942175 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,0253459 0,0793137 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0253459 0,07920593 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,0253459 0,07909846 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,0253459 0,07899128 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,0253459 0,0788844 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,0253459 0,07877779 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,0253459 0,07867148 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0253459 0,07856546 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,0253459 0,07845971 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,0253459 0,07835426 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,0253459 0,07824908 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,0253459 0,07814419 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,0253459 0,07803958 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,0253459 0,07793525 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,0253459 0,0778312 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,0253459 0,07772742 ! astrocyte differentiation GO:0048708 16 8 0,000 0,0253459 0,07762393 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,0253459 0,0775207 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,0253459 0,07741775 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,0253459 0,07731508 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,0253459 0,07721267 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,0253459 0,07711054 ! melanin metabolic process GO:0006582 12 8 0,000 0,0253459 0,07700868 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,0253459 0,07690708 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0253459 0,07680576 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,0253459 0,07670469 ! macrophage activation GO:0042116 12 8 0,000 0,0253459 0,0766039 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,0253459 0,07650337 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,0253459 0,0764031 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,0253459 0,0763031 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,0253459 0,07620336 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0253459 0,07610387 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,0253459 0,07600465 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,0253459 0,07590569 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,0253459 0,07580698 ! ruffle organization GO:0031529 11 8 0,000 0,0253459 0,07570853 ! osteoblast development GO:0002076 13 8 0,000 0,0253459 0,07561033 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,0253459 0,07551239 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,0253459 0,07541471 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,0253459 0,07531727 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,0253459 0,07522009 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,0253459 0,07512315 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,0253459 0,07502647 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,0253459 0,07493004 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,0253459 0,07483385 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,0253459 0,07473791 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,0253459 0,07464221 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,0253459 0,07454676 ! oligodendrocyte development GO:0014003 8 8 0,000 0,0253459 0,07445156 ! segment specification GO:0007379 10 8 0,000 0,0253459 0,07435659 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,0253459 0,07426187 ! cellular extravasation GO:0045123 11 8 0,000 0,0253459 0,07416739 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,0253459 0,07407315 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,0253459 0,07397915 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,0253459 0,07388538 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,0253459 0,07379186 ! snRNA metabolic process GO:0016073 10 8 0,000 0,0253459 0,07369857 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,0253459 0,07360552 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,0253459 0,0735127 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,0253459 0,07342011 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,0253459 0,07332776 ! nucleosome disassembly GO:0006337 12 8 0,000 0,0253459 0,07323564 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,0253459 0,07314375 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,0253459 0,07305209 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,0253459 0,07296066 ! icosanoid secretion GO:0032309 12 8 0,000 0,0253459 0,07286946 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,0253459 0,07277849 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0253459 0,07268774 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,0253459 0,07259722 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,0253459 0,07250693 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,0253459 0,07241685 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,0253459 0,07232701 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,0253459 0,07223738 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,0253459 0,07214798 ! sterol catabolic process GO:0016127 9 8 0,000 0,0253459 0,0720588 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,0253459 0,07196984 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,0253459 0,0718811 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,0253459 0,07179257 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,0253459 0,07170427 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0253459 0,07161618 ! prophase GO:0051324 11 8 0,000 0,0253459 0,0715283 ! S phase GO:0051320 8 8 0,000 0,0253459 0,07144065 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,0253459 0,0713532 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,0253459 0,07126598 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,0253459 0,07117896 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,0253459 0,07109216 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,0253459 0,07100556 ! hormone catabolic process GO:0042447 13 8 0,000 0,0253459 0,07091918 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,0253459 0,07083301 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,0253459 0,07074705 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,0253459 0,07066129 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,0253459 0,07057575 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,0253459 0,07049041 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,0253459 0,07040528 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,0253459 0,07032035 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0253459 0,07023562 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,0253459 0,0701511 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,0253459 0,07006679 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,0253459 0,06998267 ! lamellipodium assembly GO:0030032 9 8 0,000 0,0253459 0,06989876 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0253459 0,06981505 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,0253459 0,06973154 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,0253459 0,06964823 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,02590963 0,07111235 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,02652878 0,07272491 ! regulation of lyase activity GO:0051339 133 79 1,000 0,02652878 0,07263833 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,02778501 0,07598755 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02846943 0,07776686 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02846943 0,07767461 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,02846943 0,07758258 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02846943 0,07749076 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02846943 0,07739917 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02846943 0,07730779 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02846943 0,07721662 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02846943 0,07712567 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02846943 0,07703494 ! GTP metabolic process GO:0046039 9 9 0,000 0,02846943 0,07694441 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02846943 0,0768541 ! social behavior GO:0035176 14 9 0,000 0,02846943 0,076764 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02846943 0,07667412 ! artery development GO:0060840 19 9 0,000 0,02846943 0,07658444 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02846943 0,07649497 ! response to pain GO:0048265 16 9 0,000 0,02846943 0,07640571 ! protein complex disassembly GO:0043241 17 9 0,000 0,02846943 0,07631666 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02846943 0,07622782 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02846943 0,07613918 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02846943 0,07605075 ! lung alveolus development GO:0048286 17 9 0,000 0,02846943 0,07596252 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02846943 0,0758745 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02846943 0,07578668 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02846943 0,07569907 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02846943 0,07561166 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02846943 0,07552445 ! protein targeting to ER GO:0045047 19 9 0,000 0,02846943 0,07543744 ! T cell selection GO:0045058 18 9 0,000 0,02846943 0,07535063 ! endoderm development GO:0007492 12 9 0,000 0,02846943 0,07526402 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02846943 0,07517761 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02846943 0,07509139 ! arginine catabolic process GO:0006527 10 9 0,000 0,02846943 0,07500538 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02846943 0,07491956 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02846943 0,07483394 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02846943 0,07474851 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02846943 0,07466328 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02846943 0,07457824 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02846943 0,0744934 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02846943 0,07440875 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02846943 0,07432429 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02846943 0,07424002 ! mannose metabolic process GO:0006013 9 9 0,000 0,02846943 0,07415594 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02846943 0,07407205 ! epithelial cell development GO:0002064 10 9 0,000 0,02846943 0,07398836 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02846943 0,07390485 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02846943 0,07382153 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02846943 0,0737384 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02846943 0,07365545 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02846943 0,07357269 ! motor axon guidance GO:0008045 14 9 0,000 0,02846943 0,07349012 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02846943 0,07340773 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02846943 0,07332553 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02846943 0,07324351 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02846943 0,07316167 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02846943 0,07308002 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02846943 0,07299855 ! DNA ligation GO:0006266 14 9 0,000 0,02846943 0,07291726 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02846943 0,07283615 ! response to amine stimulus GO:0014075 13 9 0,000 0,02846943 0,07275522 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02846943 0,07267447 ! erythrocyte development GO:0048821 11 9 0,000 0,02846943 0,0725939 ! renal water homeostasis GO:0003091 14 9 0,000 0,02846943 0,07251351 ! mRNA cleavage GO:0006379 13 9 0,000 0,02846943 0,07243329 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02846943 0,07235326 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02846943 0,07227339 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02846943 0,07219371 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02846943 0,0721142 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02846943 0,07203487 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02846943 0,07195571 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02846943 0,07187672 ! acid secretion GO:0046717 14 9 0,000 0,02846943 0,07179791 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02846943 0,07171927 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02846943 0,07164081 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02846943 0,07156251 ! purine base metabolic process GO:0006144 18 9 0,000 0,02846943 0,07148438 ! oocyte differentiation GO:0009994 12 9 0,000 0,02846943 0,07140643 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02846943 0,07132864 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02846943 0,07125103 ! spleen development GO:0048536 15 9 0,000 0,02846943 0,07117358 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02846943 0,0710963 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02846943 0,07101919 ! detection of calcium ion GO:0005513 13 9 0,000 0,02846943 0,07094225 ! blastocyst formation GO:0001825 12 9 0,000 0,02846943 0,07086547 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02846943 0,07078886 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02846943 0,07071241 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02846943 0,07063613 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02846943 0,07056002 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02846943 0,07048406 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02846943 0,07040828 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02846943 0,07033265 ! prepulse inhibition GO:0060134 14 9 0,000 0,02846943 0,07025718 ! embryonic placenta development GO:0001892 12 9 0,000 0,02846943 0,07018188 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,02846943 0,07010674 ! insulin secretion GO:0030073 17 9 0,000 0,02846943 0,07003176 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02846943 0,06995694 ! response to nicotine GO:0035094 16 9 0,000 0,02846943 0,06988228 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02846943 0,06980778 ! nucleus localization GO:0051647 15 9 0,000 0,02846943 0,06973344 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02846943 0,06965925 ! localization within membrane GO:0051668 15 9 0,000 0,02846943 0,06958522 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,02906487 0,07096518 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,030368 0,0740683 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,030368 0,07398984 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,030368 0,07391154 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,0310282 0,07543853 ! cell cycle arrest GO:0007050 150 86 1,000 0,0310282 0,07535887 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03158313 0,07662575 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03158313 0,07654501 ! neuron fate specification GO:0048665 11 10 0,000 0,03158313 0,07646443 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03158313 0,07638403 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03158313 0,07630379 ! thyroid gland development GO:0030878 19 10 0,000 0,03158313 0,07622373 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03158313 0,07614383 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03158313 0,07606409 ! synapsis GO:0007129 13 10 0,000 0,03158313 0,07598453 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03158313 0,07590513 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03158313 0,0758259 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03158313 0,07574683 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03158313 0,07566793 ! sulfate transport GO:0008272 12 10 0,000 0,03158313 0,07558919 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03158313 0,07551061 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03158313 0,0754322 ! androgen metabolic process GO:0008209 13 10 0,000 0,03158313 0,07535395 ! phospholipid efflux GO:0033700 16 10 0,000 0,03158313 0,07527587 ! hippocampus development GO:0021766 19 10 0,000 0,03158313 0,07519794 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03158313 0,07512018 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03158313 0,07504257 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03158313 0,07496513 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03158313 0,07488785 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03158313 0,07481072 ! pathogenesis GO:0009405 13 10 0,000 0,03158313 0,07473376 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03158313 0,07465695 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03158313 0,0745803 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03158313 0,07450381 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,03158313 0,07442747 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03158313 0,07435129 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03158313 0,07427527 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03158313 0,0741994 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03158313 0,07412368 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03158313 0,07404812 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03158313 0,07397272 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03158313 0,07389747 ! response to X-ray GO:0010165 16 10 0,000 0,03158313 0,07382237 ! B cell proliferation GO:0042100 14 10 0,000 0,03158313 0,07374742 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03158313 0,07367263 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03158313 0,07359798 ! forebrain cell migration GO:0021885 17 10 0,000 0,03158313 0,07352349 ! lipid digestion GO:0044241 15 10 0,000 0,03158313 0,07344915 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03158313 0,07337496 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03158313 0,07330092 ! UV protection GO:0009650 14 10 0,000 0,03158313 0,07322703 ! entry into host cell GO:0030260 20 10 0,000 0,03158313 0,07315328 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03158313 0,07307969 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03158313 0,07300624 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03158313 0,07293294 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03158313 0,07285979 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03158313 0,07278678 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03158313 0,07271392 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03158313 0,07264121 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03158313 0,07256864 ! regulation of organ growth GO:0046620 11 10 0,000 0,03158313 0,07249622 ! response to dsRNA GO:0043331 18 10 0,000 0,03158313 0,07242394 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03158313 0,0723518 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03158313 0,07227981 ! embryonic axis specification GO:0000578 12 10 0,000 0,03158313 0,07220796 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03158313 0,07213626 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03158313 0,07206469 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03158313 0,07199327 ! cranial nerve development GO:0021545 12 10 0,000 0,03158313 0,07192199 ! fucose catabolic process GO:0019317 16 10 0,000 0,03158313 0,07185085 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03158313 0,07177985 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03158313 0,07170899 ! protein sumoylation GO:0016925 12 10 0,000 0,03158313 0,07163827 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03158313 0,07156769 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03158313 0,07149725 ! zymogen activation GO:0031638 14 10 0,000 0,03158313 0,07142695 ! salivary gland development GO:0007431 22 10 0,000 0,03158313 0,07135679 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03158313 0,07128676 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03158313 0,07121687 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03158313 0,07114712 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03158313 0,0710775 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03158313 0,07100803 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03158313 0,07093868 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03158313 0,07086947 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03158313 0,0708004 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03158313 0,07073146 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03158313 0,07066266 ! detection of bacterium GO:0016045 10 10 0,000 0,03158313 0,07059398 ! embryonic gut development GO:0048566 11 10 0,000 0,03158313 0,07052545 ! activation of innate immune response GO:0002218 10 10 0,000 0,03158313 0,07045704 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03158313 0,07038877 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03158313 0,07032063 ! developmental induction GO:0031128 13 10 0,000 0,03158313 0,07025262 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03158313 0,07018474 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03158313 0,070117 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03158313 0,07004938 ! female pregnancy GO:0007565 130 87 1,000 0,03169408 0,07022774 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,03169408 0,07016015 ! reproductive developmental process GO:0003006 127 89 1,000 0,03304277 0,07307535 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,03304277 0,07300516 ! rRNA transcription GO:0009303 17 11 0,000 0,03468703 0,07656447 ! respiratory burst GO:0045730 14 11 0,000 0,03468703 0,07649106 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03468703 0,0764178 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03468703 0,07634467 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03468703 0,07627168 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,03468703 0,07619884 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03468703 0,07612613 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03468703 0,07605356 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03468703 0,07598112 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03468703 0,07590883 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,03468703 0,07583667 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03468703 0,07576465 ! mating GO:0007618 14 11 0,000 0,03468703 0,07569277 ! T cell proliferation GO:0042098 20 11 0,000 0,03468703 0,07562102 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03468703 0,07554941 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,03468703 0,07547794 ! bone resorption GO:0045453 16 11 0,000 0,03468703 0,0754066 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03468703 0,07533539 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03468703 0,07526432 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03468703 0,07519338 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03468703 0,07512258 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03468703 0,07505191 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03468703 0,07498137 ! syncytium formation GO:0006949 15 11 0,000 0,03468703 0,07491097 ! plasma membrane organization GO:0007009 18 11 0,000 0,03468703 0,07484069 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03468703 0,07477055 ! focal adhesion formation GO:0048041 24 11 0,000 0,03468703 0,07470054 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03468703 0,07463066 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03468703 0,07456092 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03468703 0,0744913 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03468703 0,07442181 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03468703 0,07435245 ! adult heart development GO:0007512 11 11 0,000 0,03468703 0,07428322 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03468703 0,07421412 ! temperature homeostasis GO:0001659 16 11 0,000 0,03468703 0,07414515 ! L-glutamate transport GO:0015813 16 11 0,000 0,03468703 0,0740763 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03468703 0,07400759 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03468703 0,073939 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03468703 0,07387054 ! stem cell development GO:0048864 29 11 0,000 0,03468703 0,0738022 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03468703 0,07373399 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03468703 0,07366591 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03468703 0,07359795 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03468703 0,07353012 ! vasoconstriction GO:0042310 15 11 0,000 0,03468703 0,07346241 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03468703 0,07339483 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03468703 0,07332737 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03468703 0,07326004 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03468703 0,07319283 ! ribosome assembly GO:0042255 13 11 0,000 0,03468703 0,07312574 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03468703 0,07305877 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03468703 0,07299193 ! chromatin silencing GO:0006342 19 11 0,000 0,03468703 0,07292521 ! nucleosome positioning GO:0016584 13 11 0,000 0,03468703 0,07285861 ! T cell homeostasis GO:0043029 20 11 0,000 0,03468703 0,07279214 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03468703 0,07272578 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,03468703 0,07265955 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03468703 0,07259343 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03468703 0,07252744 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03468703 0,07246156 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03468703 0,07239581 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03468703 0,07233017 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03468703 0,07226466 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03468703 0,07219926 ! male genitalia development GO:0030539 13 11 0,000 0,03468703 0,07213398 ! cholesterol efflux GO:0033344 19 11 0,000 0,03468703 0,07206882 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03468703 0,07200377 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03468703 0,07193885 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03468703 0,07187404 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03468703 0,07180934 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03468703 0,07174477 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03468703 0,07168031 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,03468703 0,07161596 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,03468703 0,07155173 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03468703 0,07148762 ! lysogeny GO:0030069 18 11 0,000 0,03468703 0,07142362 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03468703 0,07135973 ! acrosome reaction GO:0007340 13 11 0,000 0,03468703 0,07129596 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03468703 0,0712323 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,03510746 0,07203136 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,03580664 0,07340041 ! regulation of binding GO:0051098 151 95 1,000 0,03722116 0,07623212 ! lactation GO:0007595 20 12 0,000 0,03778116 0,07731021 ! reproductive cellular process GO:0048610 14 12 0,000 0,03778116 0,07724149 ! tRNA modification GO:0006400 14 12 0,000 0,03778116 0,07717289 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03778116 0,07710442 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,03778116 0,07703606 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03778116 0,07696783 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03778116 0,07689971 ! non-recombinational repair GO:0000726 19 12 0,000 0,03778116 0,07683172 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03778116 0,07676385 ! peroxisomal transport GO:0043574 21 12 0,000 0,03778116 0,0766961 ! cartilage condensation GO:0001502 18 12 0,000 0,03778116 0,07662846 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03778116 0,07656095 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03778116 0,07649355 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03778116 0,07642628 ! heart looping GO:0001947 15 12 0,000 0,03778116 0,07635912 ! palate development GO:0060021 15 12 0,000 0,03778116 0,07629208 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03778116 0,07622516 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03778116 0,07615835 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03778116 0,07609166 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03778116 0,07602509 ! arginine metabolic process GO:0006525 13 12 0,000 0,03778116 0,07595863 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,03778116 0,07589229 ! methionine metabolic process GO:0006555 13 12 0,000 0,03778116 0,07582607 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03778116 0,07575996 ! Golgi organization GO:0007030 18 12 0,000 0,03778116 0,07569397 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03778116 0,07562809 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,03778116 0,07556233 ! monoamine transport GO:0015844 13 12 0,000 0,03778116 0,07549668 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03778116 0,07543114 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03778116 0,07536572 ! L-amino acid transport GO:0015807 20 12 0,000 0,03778116 0,07530041 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03778116 0,07523522 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03778116 0,07517014 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03778116 0,07510517 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03778116 0,07504031 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03778116 0,07497556 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,03778116 0,07491093 ! cerebellum development GO:0021549 13 12 0,000 0,03778116 0,07484641 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,03778116 0,07478199 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03778116 0,07471769 ! histone acetylation GO:0016573 23 12 0,000 0,03778116 0,0746535 ! histone methylation GO:0016571 15 12 0,000 0,03778116 0,07458942 ! autonomic nervous system development GO:0048483 23 12 0,000 0,03778116 0,07452545 ! gland morphogenesis GO:0022612 23 12 0,000 0,03778116 0,07446159 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03778116 0,07439784 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,03778116 0,0743342 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03778116 0,07427066 ! response to gamma radiation GO:0010332 20 12 0,000 0,03778116 0,07420724 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03778116 0,07414392 ! intestinal absorption GO:0050892 19 12 0,000 0,03778116 0,07408071 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03778116 0,07401761 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03778116 0,07395462 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,03778116 0,07389173 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03778116 0,07382895 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,03778116 0,07376628 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03778116 0,07370371 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03778116 0,07364125 ! microspike assembly GO:0030035 23 12 0,000 0,03778116 0,0735789 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03778116 0,07351665 ! response to cold GO:0009409 14 12 0,000 0,03778116 0,0734545 ! response to light stimulus GO:0009416 153 96 1,000 0,03793643 0,07369408 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,03865698 0,07503043 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,04084995 0,07921997 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,04084995 0,07915324 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,04086555 0,07911681 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04086555 0,07905027 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04086555 0,07898384 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04086555 0,07891752 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04086555 0,07885132 ! water transport GO:0006833 17 13 0,000 0,04086555 0,07878522 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04086555 0,07871924 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04086555 0,07865336 ! lipid localization GO:0010876 24 13 0,000 0,04086555 0,0785876 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04086555 0,07852195 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04086555 0,0784564 ! organelle fusion GO:0048284 28 13 0,000 0,04086555 0,07839097 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04086555 0,07832564 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04086555 0,07826042 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04086555 0,07819532 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04086555 0,07813031 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04086555 0,07806542 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04086555 0,07800064 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04086555 0,07793596 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04086555 0,07787139 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04086555 0,07780693 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04086555 0,07774257 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04086555 0,07767832 ! NAD metabolic process GO:0019674 21 13 0,000 0,04086555 0,07761418 ! exocrine system development GO:0035272 27 13 0,000 0,04086555 0,07755014 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04086555 0,07748621 ! bone mineralization GO:0030282 15 13 0,000 0,04086555 0,07742238 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04086555 0,07735866 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04086555 0,07729504 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04086555 0,07723153 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04086555 0,07716812 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04086555 0,07710481 ! genitalia development GO:0048806 15 13 0,000 0,04086555 0,07704161 ! regulation of cellular pH GO:0030641 20 13 0,000 0,04086555 0,07697852 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,04086555 0,07691552 ! cellular pigmentation GO:0033059 24 13 0,000 0,04086555 0,07685263 ! tissue regeneration GO:0042246 21 13 0,000 0,04086555 0,07678984 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04086555 0,07672716 ! cofactor transport GO:0051181 19 13 0,000 0,04086555 0,07666457 ! NADP metabolic process GO:0006739 18 13 0,000 0,04086555 0,07660209 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04086555 0,07653971 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04086555 0,07647744 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04086555 0,07641526 ! gas transport GO:0015669 18 13 0,000 0,04086555 0,07635318 ! regulation of RNA stability GO:0043487 28 13 0,000 0,04086555 0,07629121 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04086555 0,07622933 ! regulation of axon extension GO:0030516 23 13 0,000 0,04086555 0,07616756 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04086555 0,07610589 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04086555 0,07604431 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04086555 0,07598284 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04086555 0,07592146 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04086555 0,07586018 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04086555 0,07579901 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04394023 0,08143636 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,04394023 0,08137079 ! superoxide anion generation GO:0042554 18 14 0,000 0,04394023 0,08130533 ! neuron maturation GO:0042551 21 14 0,000 0,04394023 0,08123997 ! regulation of S phase GO:0033261 18 14 0,000 0,04394023 0,08117472 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04394023 0,08110957 ! myotube differentiation GO:0014902 21 14 0,000 0,04394023 0,08104453 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,04394023 0,08097959 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04394023 0,08091475 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04394023 0,08085002 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04394023 0,08078539 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04394023 0,08072087 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04394023 0,08065644 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04394023 0,08059213 ! response to cAMP GO:0051591 19 14 0,000 0,04394023 0,08052791 ! limbic system development GO:0021761 25 14 0,000 0,04394023 0,08046379 ! startle response GO:0001964 21 14 0,000 0,04394023 0,08039978 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04394023 0,08033587 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04394023 0,08027206 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,04394023 0,08020835 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04394023 0,08014475 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04394023 0,08008124 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04394023 0,08001783 ! glycine metabolic process GO:0006544 22 14 0,000 0,04394023 0,07995453 ! pituitary gland development GO:0021983 23 14 0,000 0,04394023 0,07989132 ! cellular response to starvation GO:0009267 21 14 0,000 0,04394023 0,07982822 ! lysosomal transport GO:0007041 20 14 0,000 0,04394023 0,07976521 ! regulation of heart rate GO:0002027 23 14 0,000 0,04394023 0,07970231 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04394023 0,0796395 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04394023 0,07957679 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04394023 0,07951418 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04394023 0,07945167 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,04394023 0,07938926 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,04394023 0,07932694 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04394023 0,07926473 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04394023 0,07920261 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04394023 0,07914058 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04394023 0,07907866 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04394023 0,07901683 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04394023 0,0789551 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04394023 0,07889346 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04394023 0,07883192 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04394023 0,07877048 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04394023 0,07870913 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04394023 0,07864788 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04394023 0,07858672 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04394023 0,07852566 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,04394023 0,07846469 ! muscle maintenance GO:0046716 19 14 0,000 0,04394023 0,07840382 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04394023 0,07834304 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04394023 0,07828236 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04394023 0,07822177 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04394023 0,07816127 ! cell killing GO:0001906 20 14 0,000 0,04394023 0,07810087 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,04394023 0,07804056 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,04394023 0,07798034 ! cilium assembly GO:0042384 20 14 0,000 0,04394023 0,07792022 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04394023 0,07786019 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,04700522 0,08322711 ! positive regulation of cell size GO:0045793 20 15 0,000 0,04700522 0,08316309 ! metencephalon development GO:0022037 19 15 0,000 0,04700522 0,08309917 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,04700522 0,08303534 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,04700522 0,08297162 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,04700522 0,08290799 ! skin development GO:0043588 25 15 0,000 0,04700522 0,08284446 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,04700522 0,08278102 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,04700522 0,08271769 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,04700522 0,08265445 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,04700522 0,0825913 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,04700522 0,08252826 ! bile acid metabolic process GO:0008206 22 15 0,000 0,04700522 0,08246531 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,04700522 0,08240245 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,04700522 0,08233969 ! adult walking behavior GO:0007628 25 15 0,000 0,04700522 0,08227703 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,04700522 0,08221446 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,04700522 0,08215199 ! myoblast differentiation GO:0045445 27 15 0,000 0,04700522 0,08208961 ! centrosome cycle GO:0007098 16 15 0,000 0,04700522 0,08202733 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,04700522 0,08196514 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,04700522 0,08190304 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,04700522 0,08184104 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,04700522 0,08177913 ! cerebral cortex development GO:0021987 29 15 0,000 0,04700522 0,08171732 ! response to osmotic stress GO:0006970 22 15 0,000 0,04700522 0,0816556 ! vesicle coating GO:0006901 25 15 0,000 0,04700522 0,08159397 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,04700522 0,08153244 ! DNA integration GO:0015074 22 15 0,000 0,04700522 0,081471 ! peptide secretion GO:0002790 27 15 0,000 0,04700522 0,08140965 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,04700522 0,08134839 ! regulation of vasodilation GO:0042312 24 15 0,000 0,04700522 0,08128723 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,04700522 0,08122616 ! neuron recognition GO:0008038 22 15 0,000 0,04700522 0,08116518 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,04700522 0,08110429 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,04700522 0,08104349 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,04700522 0,08098278 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,04700522 0,08092217 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,04700522 0,08086164 ! biomineral formation GO:0031214 18 15 0,000 0,04700522 0,08080121 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,04700522 0,08074086 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,04700522 0,08068061 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,04700522 0,08062044 ! dopamine metabolic process GO:0042417 30 15 0,000 0,04700522 0,08056037 ! organic cation transport GO:0015695 19 15 0,000 0,04700522 0,08050038 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,04700522 0,08044049 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,04700522 0,08038068 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,04700522 0,08032096 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,04700522 0,08026133 ! defense response to virus GO:0051607 27 15 0,000 0,04700522 0,08020179 ! peptide hormone processing GO:0016486 19 15 0,000 0,04700522 0,08014234 ! protein secretion GO:0009306 27 16 0,000 0,05006057 0,08528838 ! hormone secretion GO:0046879 25 16 0,000 0,05006057 0,08522525 ! bone remodeling GO:0046849 24 16 0,000 0,05006057 0,08516221 ! endothelial cell migration GO:0043542 22 16 0,000 0,05006057 0,08509927 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05006057 0,08503642 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,05006057 0,08497366 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05006057 0,08491099 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05006057 0,08484842 ! glial cell development GO:0021782 24 16 0,000 0,05006057 0,08478594 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05006057 0,08472355 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05006057 0,08466126 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,05006057 0,08459905 ! protein polyubiquitination GO:0000209 26 16 0,000 0,05006057 0,08453694 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,05006057 0,08447491 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,05006057 0,08441298 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,05006057 0,08435114 ! fructose metabolic process GO:0006000 20 16 0,000 0,05006057 0,08428939 ! regulation of protein binding GO:0043393 27 16 0,000 0,05006057 0,08422773 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05006057 0,08416616 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,05006057 0,08410468 ! protein export from nucleus GO:0006611 24 16 0,000 0,05006057 0,08404329 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05006057 0,08398199 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,05006057 0,08392078 ! DNA replication initiation GO:0006270 25 16 0,000 0,05006057 0,08385966 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05006057 0,08379862 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,05006057 0,08373768 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05006057 0,08367682 ! diencephalon development GO:0021536 25 16 0,000 0,05006057 0,08361606 ! oogenesis GO:0048477 23 16 0,000 0,05006057 0,08355538 ! neural crest cell migration GO:0001755 24 16 0,000 0,05006057 0,08349479 ! G1 phase GO:0051318 27 16 0,000 0,05006057 0,08343428 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,05006057 0,08337387 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05006057 0,08331354 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05006057 0,0832533 ! steroid catabolic process GO:0006706 22 16 0,000 0,05006057 0,08319314 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05006057 0,08313308 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05006057 0,08307309 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05006057 0,0830132 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05006057 0,08295339 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05006057 0,08289367 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,05006057 0,08283404 ! nerve development GO:0021675 18 16 0,000 0,05006057 0,08277449 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,05006057 0,08271502 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05006057 0,08265564 ! negative regulation of translation GO:0017148 22 16 0,000 0,05006057 0,08259635 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,05310629 0,08755876 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,05310629 0,08749604 ! negative regulation of defense response GO:0031348 19 17 0,000 0,05310629 0,08743341 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,05310629 0,08737087 ! glycerol metabolic process GO:0006071 20 17 0,000 0,05310629 0,08730842 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,05310629 0,08724605 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,05310629 0,08718378 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,05310629 0,08712159 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,05310629 0,0870595 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,05310629 0,08699749 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,05310629 0,08693557 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,05310629 0,08687374 ! memory GO:0007613 25 17 0,000 0,05310629 0,08681199 ! keratinization GO:0031424 17 17 0,000 0,05310629 0,08675034 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,05310629 0,08668877 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,05310629 0,08662729 ! retinoid metabolic process GO:0001523 22 17 0,000 0,05310629 0,08656589 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,05310629 0,08650458 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,05310629 0,08644336 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,05310629 0,08638223 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,05310629 0,08632118 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,05310629 0,08626022 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,05310629 0,08619935 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,05310629 0,08613856 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,05310629 0,08607785 ! membrane budding GO:0006900 29 17 0,000 0,05310629 0,08601723 ! heme metabolic process GO:0042168 27 17 0,000 0,05310629 0,0859567 ! actin filament bundle formation GO:0051017 26 17 0,000 0,05310629 0,08589625 ! neuromuscular junction development GO:0007528 23 17 0,000 0,05310629 0,08583589 ! body fluid secretion GO:0007589 27 17 0,000 0,05310629 0,08577561 ! stem cell differentiation GO:0048863 36 17 0,000 0,05310629 0,08571542 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,05310629 0,08565531 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,05310629 0,08559529 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,05310629 0,08553535 ! sensory perception of pain GO:0019233 23 17 0,000 0,05310629 0,08547549 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,05310629 0,08541572 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,05310629 0,08535603 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,05310629 0,08529642 ! synaptogenesis GO:0007416 24 17 0,000 0,05310629 0,0852369 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,05310629 0,08517746 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,05310629 0,0851181 ! cell-cell junction organization GO:0045216 25 17 0,000 0,05310629 0,08505883 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,05310629 0,08499963 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,05310629 0,08494052 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,05310629 0,0848815 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,05310629 0,08482255 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,05310629 0,08476369 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,05310629 0,08470491 ! positive regulation of translation GO:0045727 28 18 0,000 0,05614242 0,0894855 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,05614242 0,08942353 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,05614242 0,08936165 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,05614242 0,08929985 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,05614242 0,08923813 ! cAMP metabolic process GO:0046058 33 18 0,000 0,05614242 0,0891765 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,05614242 0,08911496 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,05614242 0,0890535 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,05614242 0,08899213 ! axis specification GO:0009798 26 18 0,000 0,05614242 0,08893084 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,05614242 0,08886963 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,05614242 0,08880851 ! pancreas development GO:0031016 26 18 0,000 0,05614242 0,08874748 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,05614242 0,08868652 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,05614242 0,08862565 ! glutamine metabolic process GO:0006541 23 18 0,000 0,05614242 0,08856487 ! response to retinoic acid GO:0032526 25 18 0,000 0,05614242 0,08850417 ! pigmentation during development GO:0048066 31 18 0,000 0,05614242 0,08844355 ! central nervous system neuron development GO:0021954 30 18 0,000 0,05614242 0,08838301 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,05614242 0,08832256 ! fucose metabolic process GO:0006004 26 18 0,000 0,05614242 0,08826219 ! response to fungus GO:0009620 19 18 0,000 0,05614242 0,0882019 ! peptide cross-linking GO:0018149 31 18 0,000 0,05614242 0,08814169 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,05614242 0,08808157 ! heart process GO:0003015 27 18 0,000 0,05614242 0,08802152 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,05614242 0,08796156 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,05614242 0,08790169 ! visual learning GO:0008542 35 18 0,000 0,05614242 0,08784189 ! somitogenesis GO:0001756 24 18 0,000 0,05614242 0,08778217 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,05614242 0,08772254 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,05614242 0,08766299 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,05614242 0,08760351 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,05614242 0,08754412 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,05614242 0,08748481 ! vitamin transport GO:0051180 24 18 0,000 0,05614242 0,08742558 ! hormone transport GO:0009914 27 18 0,000 0,05614242 0,08736643 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,05614242 0,08730735 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,05614242 0,08724836 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,05614242 0,08718945 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,05614242 0,08713062 ! cell-cell recognition GO:0009988 20 18 0,000 0,05614242 0,08707187 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,05614242 0,08701319 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,05614242 0,0869546 ! regulation of glucose import GO:0046324 21 18 0,000 0,05614242 0,08689608 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,05614242 0,08683764 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,05614242 0,08677929 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,05614242 0,08672101 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,05614242 0,0866628 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,059169 0,09127343 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,059169 0,09121226 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,059169 0,09115116 ! positive regulation of ossification GO:0045778 30 19 0,000 0,059169 0,09109015 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,059169 0,09102922 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,059169 0,09096837 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,059169 0,09090761 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,059169 0,09084692 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,059169 0,09078632 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,059169 0,09072579 ! regeneration GO:0031099 32 19 0,000 0,059169 0,09066535 ! response to alkaloid GO:0043279 32 19 0,000 0,059169 0,09060499 ! sensory perception of taste GO:0050909 23 19 0,000 0,059169 0,0905447 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,059169 0,0904845 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,059169 0,09042438 ! smooth muscle contraction GO:0006939 36 19 0,000 0,059169 0,09036434 ! peroxisome organization GO:0007031 29 19 0,000 0,059169 0,09030437 ! digestive system process GO:0022600 30 19 0,000 0,059169 0,09024449 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,059169 0,09018468 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,059169 0,09012496 ! response to vitamin A GO:0033189 26 19 0,000 0,059169 0,09006531 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,059169 0,09000575 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,059169 0,08994626 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,059169 0,08988685 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,059169 0,08982752 ! response to starvation GO:0042594 30 19 0,000 0,059169 0,08976826 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,059169 0,08970909 ! plasma membrane fusion GO:0045026 23 19 0,000 0,059169 0,08964999 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,059169 0,08959097 ! cytolysis GO:0019835 20 19 0,000 0,059169 0,08953203 ! renal system process GO:0003014 35 19 0,000 0,059169 0,08947317 ! vasodilation GO:0042311 33 19 0,000 0,059169 0,08941438 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,059169 0,08935567 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,059169 0,08929704 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,059169 0,08923848 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,059169 0,08918001 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,059169 0,0891216 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,059169 0,08906328 ! sarcomere organization GO:0045214 23 19 0,000 0,059169 0,08900503 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,059169 0,08894686 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,059169 0,08888876 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,059169 0,08883074 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,059169 0,08877279 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,059169 0,08871492 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,059169 0,08865713 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,059169 0,08859941 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,06218603 0,09305652 ! iron ion transport GO:0006826 37 20 0,000 0,06218603 0,09299602 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,06218603 0,09293559 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,06218603 0,09287524 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,06218603 0,09281498 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,06218603 0,09275478 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,06218603 0,09269467 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,06218603 0,09263464 ! spinal cord development GO:0021510 31 20 0,000 0,06218603 0,09257468 ! response to ethanol GO:0045471 37 20 0,000 0,06218603 0,0925148 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,06218603 0,09245499 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,06218603 0,09239527 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,06218603 0,09233562 ! chromosome condensation GO:0030261 31 20 0,000 0,06218603 0,09227605 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,06218603 0,09221655 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,06218603 0,09215714 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,06218603 0,0920978 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,06218603 0,09203853 ! pallium development GO:0021543 38 20 0,000 0,06218603 0,09197934 ! DNA modification GO:0006304 28 20 0,000 0,06218603 0,09192023 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,06218603 0,09186119 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,06218603 0,09180223 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,06218603 0,09174335 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,06218603 0,09168454 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,06218603 0,0916258 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,06218603 0,09156714 ! collagen catabolic process GO:0030574 25 20 0,000 0,06218603 0,09150856 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,06218603 0,09145005 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,06218603 0,09139161 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,06218603 0,09133325 ! alditol metabolic process GO:0019400 24 20 0,000 0,06218603 0,09127497 ! actin filament-based movement GO:0030048 34 20 0,000 0,06218603 0,09121676 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,06519357 0,09556737 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,06519357 0,0955065 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,06519357 0,09544571 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,06519357 0,09538499 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,06519357 0,09532435 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,06519357 0,09526379 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,06519357 0,09520331 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,06519357 0,0951429 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,06519357 0,09508257 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,06519357 0,09502231 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,06519357 0,09496213 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,06519357 0,09490203 ! protein amino acid acylation GO:0043543 37 21 0,000 0,06519357 0,094842 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,06519357 0,09478205 ! vesicle docking GO:0048278 27 21 0,000 0,06519357 0,09472218 ! phototransduction GO:0007602 25 21 0,000 0,06519357 0,09466238 ! visual behavior GO:0007632 39 21 0,000 0,06519357 0,09460265 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,06519357 0,09454301 ! ovarian follicle development GO:0001541 30 21 0,000 0,06519357 0,09448343 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,06519357 0,09442393 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,06519357 0,09436451 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,06519357 0,09430516 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,06519357 0,09424589 ! cell aging GO:0007569 32 21 0,000 0,06519357 0,09418669 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,06519357 0,09412756 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,06519357 0,09406851 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,06519357 0,09400953 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,06519357 0,09395063 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,06519357 0,0938918 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,06519357 0,09383305 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,06519357 0,09377436 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,06519357 0,09371575 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,06519357 0,09365722 ! fatty acid transport GO:0015908 30 21 0,000 0,06519357 0,09359876 ! immunoglobulin production GO:0002377 33 21 0,000 0,06519357 0,09354037 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,06519357 0,09348205 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,06519357 0,09342381 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,06519357 0,09336563 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,06519357 0,09330753 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,06519357 0,09324951 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,06519357 0,09319155 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,06519357 0,09313367 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,06519357 0,09307586 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,06519357 0,09301812 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,06519357 0,09296045 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,06519357 0,09290285 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,06519357 0,09284533 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,06519357 0,09278788 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,06519357 0,09273049 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,06519357 0,09267318 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,06819163 0,09687508 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,06819163 0,09681528 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,06819163 0,09675555 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,06819163 0,0966959 ! viral genome replication GO:0019079 29 22 0,000 0,06819163 0,09663632 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,06819163 0,09657682 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,06819163 0,09651738 ! leukocyte adhesion GO:0007159 38 22 0,000 0,06819163 0,09645803 ! molting cycle process GO:0022404 40 22 0,000 0,06819163 0,09639874 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,06819163 0,09633953 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,06819163 0,09628039 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,06819163 0,09622132 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,06819163 0,09616232 ! vasculogenesis GO:0001570 33 22 0,000 0,06819163 0,0961034 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,06819163 0,09604455 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,06819163 0,09598577 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,06819163 0,09592706 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,06819163 0,09586843 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,06819163 0,09580987 ! lysosome organization GO:0007040 37 22 0,000 0,06819163 0,09575137 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,06819163 0,09569295 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,06819163 0,0956346 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,06819163 0,09557633 ! regulation of behavior GO:0050795 38 22 0,000 0,06819163 0,09551812 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,06819163 0,09545998 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,06819163 0,09540192 ! membrane depolarization GO:0051899 35 22 0,000 0,06819163 0,09534392 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,06819163 0,095286 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,06819163 0,09522814 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,06819163 0,09517036 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,06819163 0,09511264 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,06819163 0,095055 ! blastocyst development GO:0001824 37 22 0,000 0,06819163 0,09499743 ! neural tube closure GO:0001843 33 22 0,000 0,06819163 0,09493992 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,06819163 0,09488249 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,07118025 0,098981 ! neuron fate commitment GO:0048663 32 23 0,000 0,07118025 0,09892119 ! embryonic pattern specification GO:0009880 31 23 0,000 0,07118025 0,09886146 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,07118025 0,09880179 ! myelination GO:0042552 35 23 0,000 0,07118025 0,0987422 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,07118025 0,09868268 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,07118025 0,09862324 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,07118025 0,09856386 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,07118025 0,09850456 ! vesicle targeting GO:0006903 32 23 0,000 0,07118025 0,09844532 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,07118025 0,09838616 ! osteoblast differentiation GO:0001649 40 23 0,000 0,07118025 0,09832707 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,07118025 0,09826805 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,07118025 0,0982091 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,07118025 0,09815022 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,07118025 0,09809141 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,07118025 0,09803268 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,07118025 0,09797401 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,07118025 0,09791541 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,07118025 0,09785689 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,07118025 0,09779843 ! cell fate determination GO:0001709 45 23 0,000 0,07118025 0,09774004 ! pentose metabolic process GO:0019321 31 23 0,000 0,07118025 0,09768173 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,07118025 0,09762348 ! spermatid development GO:0007286 33 23 0,000 0,07118025 0,0975653 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,07118025 0,09750719 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,07118025 0,09744915 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,07118025 0,09739118 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,07118025 0,09733328 ! telomere organization GO:0032200 32 23 0,000 0,07118025 0,09727544 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,07118025 0,09721768 ! regulation of amine transport GO:0051952 38 23 0,000 0,07118025 0,09715998 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,07415945 0,10116651 ! initiation of viral infection GO:0019059 42 24 0,000 0,07415945 0,10110654 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,07415945 0,10104665 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,07415945 0,10098682 ! superoxide metabolic process GO:0006801 32 24 0,000 0,07415945 0,10092706 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,07415945 0,10086738 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,07415945 0,10080777 ! fat cell differentiation GO:0045444 37 24 0,000 0,07415945 0,10074822 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,07415945 0,10068875 ! sperm motility GO:0030317 27 24 0,000 0,07415945 0,10062934 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,07415945 0,10057001 ! vacuole organization GO:0007033 39 24 0,000 0,07415945 0,10051075 ! neural crest cell development GO:0014032 39 24 0,000 0,07415945 0,10045155 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,07415945 0,10039243 ! primary neural tube formation GO:0014020 35 24 0,000 0,07415945 0,10033338 ! negative regulation of cell development GO:0010721 56 24 0,000 0,07415945 0,10027439 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,07415945 0,10021548 ! base-excision repair GO:0006284 31 24 0,000 0,07415945 0,10015663 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,07415945 0,10009785 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,07415945 0,10003914 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,07415945 0,0999805 ! glutathione metabolic process GO:0006749 29 24 0,000 0,07415945 0,09992193 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,07415945 0,09986343 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,07415945 0,099805 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,07415945 0,09974663 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,07712927 0,10368049 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,07712927 0,10361993 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,07712927 0,10355944 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,07712927 0,10349902 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,07712927 0,10343867 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,07712927 0,10337839 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,07712927 0,10331818 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,07712927 0,10325804 ! peptide transport GO:0015833 43 25 0,000 0,07712927 0,10319797 ! male gonad development GO:0008584 33 25 0,000 0,07712927 0,10313798 ! iron ion homeostasis GO:0055072 39 25 0,000 0,07712927 0,10307805 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,07712927 0,10301819 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,07712927 0,1029584 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,07712927 0,10289868 ! phospholipid transport GO:0015914 35 25 0,000 0,07712927 0,10283903 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,07712927 0,10277944 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,07712927 0,10271993 ! detection of light stimulus GO:0009583 30 25 0,000 0,07712927 0,10266049 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,07712927 0,10260111 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,07712927 0,1025418 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,07712927 0,10248256 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,08008973 0,10635472 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,08008973 0,10629335 ! translational initiation GO:0006413 43 26 0,000 0,08008973 0,10623205 ! regulation of pH GO:0006885 36 26 0,000 0,08008973 0,10617082 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,08008973 0,10610966 ! circadian rhythm GO:0007623 42 26 0,000 0,08008973 0,10604858 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,08008973 0,10598756 ! post-embryonic development GO:0009791 42 26 0,000 0,08008973 0,10592661 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,08008973 0,10586573 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,08008973 0,10580493 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,08008973 0,10574419 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,08008973 0,10568352 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,08008973 0,10562292 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,08008973 0,10556239 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,08008973 0,10550193 ! regulation of coagulation GO:0050818 39 26 0,000 0,08008973 0,10544154 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,08304086 0,10926429 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,08304086 0,10920182 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,08304086 0,10913942 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,08304086 0,10907709 ! membrane docking GO:0022406 39 27 0,000 0,08304086 0,10901483 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,08304086 0,10895264 ! catechol metabolic process GO:0009712 43 27 0,000 0,08304086 0,10889053 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,08304086 0,10882848 ! acute-phase response GO:0006953 42 27 0,000 0,08304086 0,10876651 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,08304086 0,1087046 ! myofibril assembly GO:0030239 36 27 0,000 0,08304086 0,10864277 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,08304086 0,108581 ! response to ionizing radiation GO:0010212 47 27 0,000 0,08304086 0,10851931 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,08304086 0,10845769 ! natural killer cell activation GO:0030101 35 27 0,000 0,08304086 0,10839613 ! lipid oxidation GO:0034440 38 27 0,000 0,08304086 0,10833465 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,08304086 0,10827323 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,08304086 0,10821189 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,08304086 0,10815061 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,08304086 0,10808941 ! gene silencing GO:0016458 41 27 0,000 0,08304086 0,10802827 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,0859827 0,11179209 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,0859827 0,11172893 ! phenol metabolic process GO:0018958 44 28 0,000 0,0859827 0,11166584 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,0859827 0,11160282 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,0859827 0,11153988 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,0859827 0,111477 ! cell junction assembly GO:0034329 56 28 0,000 0,0859827 0,1114142 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,0859827 0,11135146 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,0859827 0,1112888 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,0859827 0,11122621 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,0859827 0,11116369 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,0859827 0,11110124 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,0859827 0,11103886 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,0859827 0,11097654 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,0859827 0,1109143 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,0859827 0,11085213 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,0859827 0,11079003 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,0859827 0,110728 ! mesoderm formation GO:0001707 46 28 0,000 0,0859827 0,11066603 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,0859827 0,11060414 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,0859827 0,11054231 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,0859827 0,11048056 ! ensheathment of neurons GO:0007272 43 28 0,000 0,0859827 0,11041887 GO:0008366|axon ensheathment, ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,0859827 0,11035726 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,0859827 0,11029571 ! placenta development GO:0001890 37 28 0,000 0,0859827 0,11023423 ! regulation of B cell activation GO:0050864 42 28 0,000 0,0859827 0,11017281 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,08891526 0,11386698 ! regulation of innate immune response GO:0045088 38 29 0,000 0,08891526 0,11380362 ! ovulation cycle process GO:0022602 41 29 0,000 0,08891526 0,11374032 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,08891526 0,1136771 ! protein targeting to membrane GO:0006612 53 29 0,000 0,08891526 0,11361394 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,08891526 0,11355086 ! mismatch repair GO:0006298 34 29 0,000 0,08891526 0,11348785 ! muscle cell development GO:0055001 38 29 0,000 0,08891526 0,1134249 ! formation of primary germ layer GO:0001704 48 29 0,000 0,08891526 0,11336203 ! telencephalon development GO:0021537 52 29 0,000 0,08891526 0,11329922 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,08891526 0,11323649 ! eye morphogenesis GO:0048592 51 29 0,000 0,08891526 0,11317382 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,08891526 0,11311123 ! tissue homeostasis GO:0001894 42 29 0,000 0,08891526 0,1130487 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,09183858 0,11670096 ! collagen metabolic process GO:0032963 40 30 0,000 0,09183858 0,11663652 ! organic anion transport GO:0015711 51 30 0,000 0,09183858 0,11657215 ! cholesterol transport GO:0030301 46 30 0,000 0,09183858 0,11650785 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,09183858 0,11644363 ! spliceosome assembly GO:0000245 49 30 0,000 0,09183858 0,11637947 ! spindle organization GO:0007051 37 30 0,000 0,09183858 0,11631539 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,09183858 0,11625137 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,09183858 0,11618743 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,09183858 0,11612355 ! ceramide metabolic process GO:0006672 43 30 0,000 0,09183858 0,11605975 ! ovulation cycle GO:0042698 43 30 0,000 0,09183858 0,11599601 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,09183858 0,11593235 ! adult locomotory behavior GO:0008344 47 30 0,000 0,09183858 0,11586875 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,09183858 0,11580523 ! response to heat GO:0009408 41 30 0,000 0,09183858 0,11574178 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,09183858 0,11567839 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,09183858 0,11561507 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,09475269 0,11921838 ! negative regulation of secretion GO:0051048 49 31 0,000 0,09475269 0,11915319 ! mammary gland development GO:0030879 57 31 0,000 0,09475269 0,11908808 ! glial cell differentiation GO:0010001 55 31 0,000 0,09475269 0,11902304 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,09475269 0,11895807 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,09475269 0,11889318 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,09475269 0,11882835 ! odontogenesis GO:0042476 50 31 0,000 0,09475269 0,11876359 ! segmentation GO:0035282 41 31 0,000 0,09475269 0,11869891 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,09475269 0,11863429 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,09475269 0,11856975 ! metanephros development GO:0001656 58 31 0,000 0,09475269 0,11850527 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,09475269 0,11844086 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,09475269 0,11837653 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,09475269 0,11831226 ! cell fate specification GO:0001708 37 31 0,000 0,09475269 0,11824807 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,09475269 0,11818394 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,09475269 0,11811989 ! RNA modification GO:0009451 40 31 0,000 0,09475269 0,1180559 ! regulation of muscle development GO:0048634 48 32 0,000 0,09765762 0,12160938 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,09765762 0,12154357 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,09765762 0,12147784 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,09765762 0,12141217 ! meiosis I GO:0007127 52 32 0,000 0,09765762 0,12134658 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,09765762 0,12128106 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,09765762 0,12121561 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,09765762 0,12115023 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,09765762 0,12108492 ! peripheral nervous system development GO:0007422 53 32 0,000 0,09765762 0,12101968 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,09765762 0,12095451 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,09765762 0,12088941 ! cytokine production GO:0001816 44 32 0,000 0,09765762 0,12082438 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,09765762 0,12075942 ! vesicle localization GO:0051648 47 32 0,000 0,09765762 0,12069453 ! RNA export from nucleus GO:0006405 44 33 0,000 0,10055339 0,12420665 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,10055339 0,12413998 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,10055339 0,12407338 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,10055339 0,12400686 ! sister chromatid segregation GO:0000819 46 33 0,000 0,10055339 0,1239404 ! ear morphogenesis GO:0042471 42 33 0,000 0,10055339 0,12387402 ! actomyosin structure organization GO:0031032 43 33 0,000 0,10055339 0,1238077 ! cell junction organization GO:0034330 63 33 0,000 0,10055339 0,12374146 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,10055339 0,12367529 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,10055339 0,12360919 ! nucleus organization GO:0006997 49 33 0,000 0,10055339 0,12354316 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,10055339 0,1234772 ! female gonad development GO:0008585 49 33 0,000 0,10055339 0,12341131 ! positive regulation of cell development GO:0010720 54 33 0,000 0,10055339 0,12334549 ! lipid homeostasis GO:0055088 55 33 0,000 0,10055339 0,12327974 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,10055339 0,12321406 ! regulation of proteolysis GO:0030162 50 33 0,000 0,10055339 0,12314845 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,10055339 0,12308291 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,10055339 0,12301744 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,10055339 0,12295204 ! cytokinesis GO:0000910 52 33 0,000 0,10055339 0,12288671 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,10055339 0,12282145 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,10344003 0,12628029 ! mRNA catabolic process GO:0006402 48 34 0,000 0,10344003 0,1262133 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,10344003 0,12614638 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,10344003 0,12607953 ! feeding behavior GO:0007631 45 34 0,000 0,10344003 0,12601275 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,10344003 0,12594604 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,10344003 0,1258794 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,10344003 0,12581283 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,10344003 0,12574633 ! neuron migration GO:0001764 46 34 0,000 0,10344003 0,12567991 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,10344003 0,12561355 ! female gamete generation GO:0007292 43 34 0,000 0,10344003 0,12554726 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,10344003 0,12548105 ! aerobic respiration GO:0009060 47 34 0,000 0,10344003 0,1254149 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,10344003 0,12534882 ! embryonic organ development GO:0048568 45 34 0,000 0,10344003 0,12528281 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,10344003 0,12521688 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,10631757 0,12863252 ! Notch signaling pathway GO:0007219 56 35 0,000 0,10631757 0,12856489 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,10631757 0,12849733 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,10631757 0,12842984 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,10631757 0,12836242 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,10631757 0,12829507 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,10631757 0,1282278 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,10631757 0,12816059 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,10631757 0,12809346 ! pigment metabolic process GO:0042440 61 35 0,000 0,10631757 0,12802639 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,10631757 0,1279594 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,10918604 0,13134304 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,10918604 0,13127438 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,10918604 0,1312058 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,10918604 0,13113728 ! organic ether metabolic process GO:0018904 46 36 0,000 0,10918604 0,13106884 ! tissue remodeling GO:0048771 62 36 0,000 0,10918604 0,13100047 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,10918604 0,13093217 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,10918604 0,13086394 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,10918604 0,13079578 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,10918604 0,13072769 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,11204547 0,13408147 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,11204547 0,13401174 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,11204547 0,13394209 ! learning GO:0007612 67 37 0,000 0,11204547 0,13387251 ! ion transmembrane transport GO:0034220 56 37 0,000 0,11204547 0,133803 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,11204547 0,13373357 ! regulation of protein secretion GO:0050708 51 37 0,000 0,11204547 0,1336642 ! amino acid activation GO:0043038 52 37 0,000 0,11204547 0,13359491 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,11204547 0,13352569 ! gliogenesis GO:0042063 71 38 0,000 0,11489588 0,13685165 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,11489588 0,13678081 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,11489588 0,13671005 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,11489588 0,13663936 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,11489588 0,13656875 ! phagocytosis GO:0006909 60 38 0,000 0,11489588 0,13649821 ! mesenchymal cell development GO:0014031 64 38 0,000 0,11489588 0,13642774 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,11489588 0,13635734 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,11773731 0,13965746 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,11773731 0,13958547 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,11773731 0,13951355 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,11773731 0,13944171 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,11773731 0,13936995 ! male sex differentiation GO:0046661 53 39 0,000 0,11773731 0,13929826 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,11773731 0,13922664 ! chromatin remodeling GO:0006338 68 39 0,000 0,11773731 0,13915509 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,11773731 0,13908362 ! JNK cascade GO:0007254 54 39 0,000 0,11773731 0,13901222 ! developmental growth GO:0048589 62 39 0,000 0,11773731 0,1389409 ! cell growth GO:0016049 61 39 0,000 0,11773731 0,13886965 ! synapse organization GO:0050808 55 39 0,000 0,11773731 0,13879847 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,12056977 0,1420648 ! response to calcium ion GO:0051592 58 40 0,000 0,12056977 0,14199205 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,12056977 0,14191939 ! regulation of tube size GO:0035150 60 40 0,000 0,12056977 0,14184679 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,12056977 0,14177427 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,12056977 0,14170183 ! peptide metabolic process GO:0006518 56 40 0,000 0,12056977 0,14162946 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,12056977 0,14155716 ! inner ear development GO:0048839 57 40 0,000 0,12056977 0,14148494 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,12056977 0,14141279 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,12056977 0,14134071 ! double-strand break repair GO:0006302 67 40 0,000 0,12056977 0,14126871 ! B cell differentiation GO:0030183 62 40 0,000 0,12056977 0,14119678 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,12056977 0,14112493 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,12056977 0,14105314 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,12056977 0,14098143 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,12339331 0,14420966 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,12339331 0,14413642 ! glucose transport GO:0015758 52 41 0,000 0,12339331 0,14406325 ! striated muscle contraction GO:0006941 62 41 0,000 0,12339331 0,14399016 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,12339331 0,14391715 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,12339331 0,1438442 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,12339331 0,14377133 ! biopolymer methylation GO:0043414 62 41 0,000 0,12339331 0,14369854 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,12339331 0,14362582 ! mitochondrial transport GO:0006839 60 42 0,000 0,12620794 0,14682765 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,12620794 0,14675342 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,12620794 0,14667926 ! cellular component disassembly GO:0022411 64 42 0,000 0,12620794 0,14660518 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,12620794 0,14653118 ! hexose transport GO:0008645 54 42 0,000 0,12620794 0,14645725 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,12620794 0,14638339 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,12620794 0,14630961 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,12620794 0,1462359 ! excretion GO:0007588 63 42 0,000 0,12620794 0,14616227 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,12620794 0,14608871 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,12620794 0,14601522 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,12620794 0,14594181 ! regulation of cell shape GO:0008360 78 42 0,000 0,12620794 0,14586847 ! positive regulation of binding GO:0051099 59 43 0,000 0,12901369 0,14903641 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,12901369 0,14896159 ! leukocyte migration GO:0050900 60 43 0,000 0,12901369 0,14888685 ! neuromuscular process GO:0050905 79 43 0,000 0,12901369 0,14881219 ! activation of caspase activity GO:0006919 65 43 0,000 0,12901369 0,14873759 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,12901369 0,14866307 ! tRNA processing GO:0008033 49 43 0,000 0,12901369 0,14858863 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,12901369 0,14851426 ! vesicle organization GO:0016050 79 43 0,000 0,12901369 0,14843997 ! methylation GO:0032259 64 43 0,000 0,12901369 0,14836575 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,1318106 0,15150644 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,1318106 0,15143076 ! glycolysis GO:0006096 53 44 0,000 0,1318106 0,15135516 ! regulation of action potential GO:0001508 71 44 0,000 0,1318106 0,15127963 ! regulation of ion transport GO:0043269 57 44 0,000 0,1318106 0,15120418 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,1318106 0,1511288 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,1318106 0,1510535 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,1318106 0,15097828 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,1318106 0,15090313 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,1318106 0,15082805 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,1318106 0,15075305 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,1318106 0,15067812 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,1318106 0,15060327 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,13459868 0,1537125 ! RNA catabolic process GO:0006401 64 45 0,000 0,13459868 0,15363621 ! positive regulation of defense response GO:0031349 59 45 0,000 0,13459868 0,15356001 ! regulation of translational initiation GO:0006446 64 45 0,000 0,13459868 0,15348387 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,13459868 0,15340782 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,13459868 0,15333183 ! cell recognition GO:0008037 58 45 0,000 0,13459868 0,15325593 ! cell maturation GO:0048469 60 45 0,000 0,13459868 0,1531801 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,13737797 0,15626575 ! cell redox homeostasis GO:0045454 63 46 0,000 0,13737797 0,1561885 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,13737797 0,15611133 ! regulation of ossification GO:0030278 71 46 0,000 0,13737797 0,15603424 ! histone modification GO:0016570 68 46 0,000 0,13737797 0,15595723 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,13737797 0,15588029 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,1401485 0,15894553 ! viral infectious cycle GO:0019058 71 47 0,000 0,1401485 0,1588672 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,1401485 0,15878894 ! endocrine system development GO:0035270 83 47 0,000 0,1401485 0,15871075 ! covalent chromatin modification GO:0016569 75 47 0,000 0,1401485 0,15863265 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,1401485 0,15855462 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,1401485 0,15847667 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,1401485 0,15839879 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,1401485 0,15832099 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,1401485 0,15824327 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,1401485 0,15816562 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,1401485 0,15808805 ! chloride transport GO:0006821 67 48 0,000 0,14291028 0,16112433 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,14291028 0,16104539 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,14291028 0,16096652 ! response to temperature stimulus GO:0009266 62 48 0,000 0,14291028 0,16088773 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,14291028 0,16080902 ! gastrulation GO:0007369 73 48 0,000 0,14291028 0,16073039 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,14291028 0,16065183 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,14291028 0,16057335 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,14291028 0,16049494 ! regulation of endocytosis GO:0030100 63 48 0,000 0,14291028 0,16041661 ! nuclear export GO:0051168 69 48 0,000 0,14291028 0,16033836 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,14291028 0,16026019 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,14291028 0,16018209 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,14566335 0,16318836 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,14566335 0,16310891 ! sensory perception of smell GO:0007608 61 49 0,000 0,14566335 0,16302954 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,14566335 0,16295024 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,14566335 0,16287103 ! RNA elongation GO:0006354 62 49 0,000 0,14566335 0,16279189 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,14566335 0,16271282 ! germ cell development GO:0007281 68 49 0,000 0,14566335 0,16263384 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,14566335 0,16255493 ! cartilage development GO:0051216 70 49 0,000 0,14566335 0,16247609 ! regulation of actin filament length GO:0030832 72 50 0,000 0,14840773 0,165457 ! ear development GO:0043583 72 50 0,000 0,14840773 0,16537683 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,14840773 0,16529675 ! membrane fusion GO:0006944 80 50 0,000 0,14840773 0,16521674 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,14840773 0,16513681 ! proton transport GO:0015992 75 50 0,000 0,14840773 0,16505696 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,14840773 0,16497718 ! positive regulation of secretion GO:0051047 71 51 0,000 0,15114346 0,16793718 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,15114346 0,16785609 ! hydrogen transport GO:0006818 77 51 0,000 0,15114346 0,16777507 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,15114346 0,16769414 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,15114346 0,16761329 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,15114346 0,16753251 ! adult behavior GO:0030534 80 51 0,000 0,15114346 0,16745181 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,15114346 0,16737119 ! transition metal ion transport GO:0000041 74 52 0,000 0,15387055 0,17030908 ! regulation of cellular component size GO:0032535 74 52 0,000 0,15387055 0,17022716 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,15387055 0,17014532 ! aging GO:0007568 79 52 0,000 0,15387055 0,17006356 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,15387055 0,16998188 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,15387055 0,16990027 ! establishment of organelle localization GO:0051656 85 52 0,000 0,15387055 0,16981875 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,15658904 0,17273611 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,15658904 0,1726533 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,15658904 0,17257058 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,15658904 0,17248793 ! kidney development GO:0001822 90 53 0,000 0,15658904 0,17240536 ! single fertilization GO:0007338 59 53 0,000 0,15658904 0,17232287 ! cell projection assembly GO:0030031 76 53 0,000 0,15658904 0,17224046 ! amino acid transport GO:0006865 84 54 0,000 0,15929895 0,17513747 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,15929895 0,17505379 ! regulation of mitosis GO:0007088 84 54 0,000 0,15929895 0,17497019 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,15929895 0,17488668 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,15929895 0,17480324 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,15929895 0,17471988 ! DNA catabolic process GO:0006308 67 54 0,000 0,15929895 0,1746366 ! detection of external stimulus GO:0009581 66 54 0,000 0,15929895 0,1745534 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,15929895 0,17447028 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,15929895 0,17438724 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,15929895 0,17430427 ! exocytosis GO:0006887 74 55 0,000 0,16200031 0,1771758 ! mesoderm development GO:0007498 76 55 0,000 0,16200031 0,17709159 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,16200031 0,17700746 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,16200031 0,17692341 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,16469314 0,17977894 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,16469314 0,17969365 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,16469314 0,17960845 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,16737747 0,18244938 ! carbohydrate transport GO:0008643 74 57 0,000 0,16737747 0,18236295 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,16737747 0,1822766 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,16737747 0,18219034 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,16737747 0,18210416 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,16737747 0,18201806 ! camera-type eye development GO:0043010 88 57 0,000 0,16737747 0,18193204 ! secondary metabolic process GO:0019748 84 57 0,000 0,16737747 0,1818461 ! developmental maturation GO:0021700 75 57 0,000 0,16737747 0,18176024 ! gonad development GO:0008406 79 57 0,000 0,16737747 0,18167446 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,17005333 0,18449182 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,17005333 0,18440484 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,17005333 0,18431794 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,17005333 0,18423112 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,17272075 0,18703282 ! lung development GO:0030324 94 59 0,000 0,17272075 0,18694481 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,17272075 0,18685687 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,17272075 0,18676902 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,17537974 0,18955517 GO:0035113|embryonic appendage morphogenesis, ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,17537974 0,18946613 ! regulation of heart contraction GO:0008016 91 60 0,000 0,17537974 0,18937718 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,17537974 0,18928832 ! fertilization GO:0009566 68 60 0,000 0,17537974 0,18919953 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,17537974 0,18911083 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,17803034 0,191879 ! meiosis GO:0007126 96 61 0,000 0,17803034 0,19178912 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,17803034 0,19169933 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,17803034 0,19160963 ! urogenital system development GO:0001655 101 61 0,000 0,17803034 0,19152001 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,17803034 0,19143047 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,17803034 0,19134102 ! extracellular matrix organization GO:0030198 103 61 0,000 0,17803034 0,19125165 ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,17803034 0,19116236 ! amine catabolic process GO:0009310 90 62 0,000 0,18067257 0,19390896 ! neurotransmitter transport GO:0006836 81 62 0,000 0,18067257 0,19381852 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,18067257 0,19372816 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,18067257 0,19363789 ! respiratory tube development GO:0030323 99 62 0,000 0,18067257 0,1935477 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,18067257 0,19345759 ! meiotic cell cycle GO:0051321 97 62 0,000 0,18067257 0,19336757 ! organelle localization GO:0051640 96 62 0,000 0,18067257 0,19327763 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,18330646 0,19600412 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,18330646 0,19591304 ! regulation of lipase activity GO:0060191 109 63 0,000 0,18330646 0,19582204 ! negative regulation of cell size GO:0045792 108 64 0,000 0,18593203 0,19853466 ! appendage morphogenesis GO:0035107 93 64 0,000 0,18593203 0,19844254 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,18593203 0,19835049 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,18593203 0,19825854 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,18593203 0,19816667 ! hexose catabolic process GO:0019320 82 64 0,000 0,18593203 0,19807488 ! respiratory system development GO:0060541 100 64 0,000 0,18593203 0,19798318 ! adaptive immune response GO:0002250 94 64 0,000 0,18593203 0,19789156 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,18854931 0,20058437 ! appendage development GO:0048736 94 65 0,000 0,18854931 0,20049164 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,18854931 0,20039899 ! defense response to bacterium GO:0042742 73 65 0,000 0,18854931 0,20030643 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,18854931 0,20021395 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,18854931 0,20012156 ! activation of immune response GO:0002253 83 65 0,000 0,18854931 0,20002925 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,19115833 0,20270362 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,19115833 0,20261021 ! antigen processing and presentation GO:0019882 96 66 0,000 0,19115833 0,20251688 ! axon guidance GO:0007411 99 66 0,000 0,19115833 0,20242364 ! regulation of immune effector process GO:0002697 101 66 0,000 0,19115833 0,20233049 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,1937591 0,20498893 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,1937591 0,20489468 ! acute inflammatory response GO:0002526 92 68 0,000 0,19635167 0,20754082 ! learning or memory GO:0007611 123 68 0,000 0,19635167 0,20744549 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,19635167 0,20735025 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,19635167 0,20725509 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,19635167 0,20716002 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,19635167 0,20706503 ! rhythmic process GO:0048511 105 68 0,000 0,19635167 0,20697014 ! inorganic anion transport GO:0015698 93 68 0,000 0,19635167 0,20687533 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,19893604 0,20950224 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,19893604 0,20940636 ! response to drug GO:0042493 108 69 0,000 0,19893604 0,20931057 ! response to metal ion GO:0010038 103 70 0,000 0,20151225 0,21192418 ! humoral immune response GO:0006959 86 70 0,000 0,20151225 0,21182732 ! eye development GO:0001654 111 70 0,000 0,20151225 0,21173056 ! amine transport GO:0015837 101 70 0,000 0,20151225 0,21163387 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,20151225 0,21153728 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,20151225 0,21144078 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,20408033 0,21403774 ! muscle cell differentiation GO:0042692 104 71 0,000 0,20408033 0,21394018 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,20408033 0,21384271 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,20408033 0,21374534 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,20408033 0,21364805 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,20408033 0,21355084 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,20664029 0,21613127 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,20664029 0,21603303 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,20664029 0,21593488 ! regulation of blood pressure GO:0008217 107 73 0,000 0,20919217 0,21850226 ! mitochondrion organization GO:0007005 104 73 0,000 0,20919217 0,21840308 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,20919217 0,21830398 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,20919217 0,21820498 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,21173598 0,22075827 ! response to oxygen levels GO:0070482 137 74 0,000 0,21173598 0,22065825 ! digestion GO:0007586 97 74 0,000 0,21173598 0,22055831 ! protein import into nucleus GO:0006606 118 74 0,000 0,21173598 0,22045847 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,21173598 0,22035871 ! blood coagulation GO:0007596 116 75 0,000 0,21427175 0,2228969 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,21427175 0,22279613 ! negative regulation of growth GO:0045926 123 75 0,000 0,21427175 0,22269545 ! response to nutrient GO:0007584 104 75 0,000 0,21427175 0,22259487 ! nuclear import GO:0051170 121 75 0,000 0,21427175 0,22249437 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,21427175 0,22239397 ! amine biosynthetic process GO:0009309 97 76 0,000 0,21679952 0,22491605 ! tRNA metabolic process GO:0006399 95 76 0,000 0,21679952 0,22481465 ! response to unfolded protein GO:0006986 99 76 0,000 0,21679952 0,22471334 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,21679952 0,22461211 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,21931929 0,22712039 ! gland development GO:0048732 148 77 0,000 0,21931929 0,22701817 ! sex differentiation GO:0007548 105 77 0,000 0,21931929 0,22691605 ! protein ubiquitination GO:0016567 125 77 0,000 0,21931929 0,22681402 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,21931929 0,22671208 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,21931929 0,22661023 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,21931929 0,22650848 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,22183111 0,2289998 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,22183111 0,22889706 ! cellular respiration GO:0045333 107 79 0,000 0,22433498 0,23137689 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,22433498 0,23127318 ! T cell activation GO:0042110 134 79 0,000 0,22433498 0,23116956 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,22433498 0,23106604 ! chromatin assembly GO:0031497 102 80 0,000 0,22683095 0,23353231 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,22683095 0,23342782 ! protein localization in nucleus GO:0034504 133 80 0,000 0,22683095 0,23332343 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,22683095 0,23321912 ! forebrain development GO:0030900 131 80 0,000 0,22683095 0,23311491 ! hemostasis GO:0007599 125 81 0,000 0,22931902 0,23556666 ! mRNA transport GO:0051028 121 81 0,000 0,22931902 0,2354615 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,22931902 0,23535643 ! response to protein stimulus GO:0051789 111 81 0,000 0,22931902 0,23525145 ! regulation of neurological system process GO:0031644 122 81 0,000 0,22931902 0,23514657 ! vitamin metabolic process GO:0006766 103 81 0,000 0,22931902 0,23504178 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,22931902 0,23493708 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,23179923 0,23737232 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,23179923 0,23726668 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,2342716 0,2396907 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,2342716 0,23958412 ! regulation of defense response GO:0031347 117 84 0,000 0,23673616 0,24199696 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,23673616 0,24188945 ! sterol metabolic process GO:0016125 120 84 0,000 0,23673616 0,24178204 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,23919292 0,24418274 ! rRNA metabolic process GO:0016072 107 85 0,000 0,23919292 0,24407441 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,23919292 0,24396617 ! regulation of membrane potential GO:0042391 128 85 0,000 0,23919292 0,24385803 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,23919292 0,24374999 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,24164192 0,24613659 ! nucleosome organization GO:0034728 114 87 0,000 0,24408317 0,24851319 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,24408317 0,24840323 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,24408317 0,24829336 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,24408317 0,2481836 GO:0060538|skeletal muscle organ development, ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,24651671 0,25054725 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,24651671 0,25043658 ! interphase GO:0051325 159 88 0,000 0,24651671 0,25032602 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,24651671 0,25021554 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,24651671 0,25010517 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,24651671 0,2499949 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,24894255 0,2523437 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,24894255 0,25223254 ! regulation of T cell activation GO:0050863 128 89 0,000 0,24894255 0,25212147 ! leukocyte differentiation GO:0002521 143 90 0,000 0,25136072 0,25445847 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,25136072 0,25434652 ! hormone metabolic process GO:0042445 121 90 0,000 0,25136072 0,25423467 ! RNA localization GO:0006403 135 91 0,000 0,25377124 0,25655993 ! ATP metabolic process GO:0046034 137 91 0,000 0,25377124 0,25644721 ! response to virus GO:0009615 122 91 0,000 0,25377124 0,25633458 ! cell fate commitment GO:0045165 141 92 0,000 0,25617414 0,25864816 ! positive regulation of immune response GO:0050778 121 92 0,000 0,25617414 0,25853467 ! DNA recombination GO:0006310 146 92 0,000 0,25617414 0,25842128 ! sulfur metabolic process GO:0006790 118 92 0,000 0,25617414 0,25830799 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,25856944 0,26060898 ! electron transport chain GO:0022900 123 94 0,000 0,26095716 0,26290033 ! response to oxidative stress GO:0006979 141 94 0,000 0,26095716 0,26278523 ! angiogenesis GO:0001525 149 95 0,000 0,26333733 0,26506602 ! carboxylic acid transport GO:0046942 147 95 0,000 0,26333733 0,26495007 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,26570997 0,26722035 ! in utero embryonic development GO:0001701 147 96 0,000 0,26570997 0,26710355 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,26570997 0,26698686 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,26570997 0,26687027 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,26570997 0,26675379 ! protein maturation GO:0051604 129 96 0,000 0,26570997 0,2666374 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,2680751 0,26889348 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! extracellular structure organization GO:0043062 156 99 0,000 0,27278295 0,27349642 ! protein import GO:0017038 156 99 0,000 0,27278295 0,27337725 ! regulation of translation GO:0006417 151 100 0,000 0,27512571 0,27560502 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,27512571 0,27548504 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,27512571 0,27536516 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,27512571 0,27524538 ! protein localization in organelle GO:0033365 161 100 0,000 0,27512571 0,27512571