pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6614-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! oxygen transport GO:0015671 7 7 3,000 3,751E-08 6,913E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 3,000 1,339E-07 1,234E-04 ! gas transport GO:0015669 9 9 3,000 1,339E-07 8,225E-05 ! meiosis GO:0007126 37 37 4,000 2,214E-06 1,02E-03 GO:0051327|M phase of meiotic cell cycle, ! DNA damage response, signal transduction GO:0042770 37 37 4,000 2,214E-06 8,161E-04 ! meiotic cell cycle GO:0051321 38 38 4,000 2,538E-06 7,797E-04 ! meiosis I GO:0007127 18 18 3,000 3,128E-06 8,235E-04 ! cell cycle checkpoint GO:0000075 42 41 4,000 3,74E-06 8,617E-04 ! negative regulation of T cell proliferation GO:0042130 6 6 2,000 3,881E-06 7,948E-04 GO:0070667|negative regulation of mast cell proliferation, ! DNA damage checkpoint GO:0000077 19 19 3,000 3,945E-06 7,27E-04 ! DNA integrity checkpoint GO:0031570 21 21 3,000 6,039E-06 1,012E-03 ! neuron projection development GO:0031175 85 80 5,000 6,648E-06 1,021E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 2,000 6,764E-06 9,589E-04 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! negative regulation of T cell activation GO:0050868 7 7 2,000 6,764E-06 8,904E-04 ! cell cycle arrest GO:0007050 49 49 4,000 9,191E-06 1,129E-03 ! regulation of DNA metabolic process GO:0051052 51 50 4,000 1,017E-05 1,171E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 1,078E-05 1,168E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 3,000 1,476E-05 1,512E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 2,005E-05 1,944E-03 ! inositol metabolic process GO:0006020 10 10 2,000 2,29E-05 2,111E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 2,29E-05 2,01E-03 ! response to UV GO:0009411 29 29 3,000 2,315E-05 1,94E-03 ! axonogenesis GO:0007409 66 62 4,000 2,947E-05 2,361E-03 ! endothelial cell migration GO:0043542 11 11 2,000 3,136E-05 2,408E-03 ! negative regulation of lymphocyte activation GO:0051250 11 11 2,000 3,136E-05 2,312E-03 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 4,000 4,302E-05 3,05E-03 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! response to radiation GO:0009314 70 68 4,000 4,624E-05 3,156E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 4,974E-05 3,274E-03 ! cell part morphogenesis GO:0032990 75 70 4,000 5,322E-05 3,382E-03 ! regulation of DNA recombination GO:0000018 13 13 2,000 5,391E-05 3,312E-03 ! negative regulation of leukocyte activation GO:0002695 13 13 2,000 5,391E-05 3,205E-03 ! negative regulation of protein kinase activity GO:0006469 37 37 3,000 6,22E-05 3,582E-03 ! negative regulation of kinase activity GO:0033673 38 38 3,000 6,922E-05 3,866E-03 ! cell morphogenesis involved in differentiation GO:0000904 82 77 4,000 8,426E-05 4,567E-03 ! negative regulation of transferase activity GO:0051348 40 40 3,000 8,496E-05 4,474E-03 ! negative regulation of cell activation GO:0050866 15 15 2,000 8,506E-05 4,355E-03 ! polyol metabolic process GO:0019751 16 16 2,000 1,043E-04 5,193E-03 ! regulation of fibroblast proliferation GO:0048145 17 17 2,000 1,261E-04 6,114E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 1,428E-04 6,747E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 1,507E-04 6,942E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 1,592E-04 7,157E-03 GO:0033674|positive regulation of kinase activity, ! negative regulation of DNA metabolic process GO:0051053 19 19 2,000 1,782E-04 7,818E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 1,782E-04 7,636E-03 ! regulation of protein stability GO:0031647 19 19 2,000 1,782E-04 7,463E-03 ! negative regulation of cell cycle GO:0045786 92 91 4,000 1,865E-04 7,64E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 1,895E-04 7,592E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 2,087E-04 8,185E-03 ! response to light stimulus GO:0009416 53 52 3,000 2,39E-04 9,178E-03 ! prostate gland development GO:0030850 5 5 1,000 3,426E-04 0,01288625 ! central nervous system neuron axonogenesis GO:0021955 6 5 1,000 3,426E-04 0,01262853 GO:0021952|central nervous system projection neuron axonogenesis, ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 3,426E-04 0,01238091 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 3,426E-04 0,01214282 ! T cell lineage commitment GO:0002360 5 5 1,000 3,426E-04 0,01191371 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 3,426E-04 0,01169308 ! male genitalia development GO:0030539 5 5 1,000 3,426E-04 0,01148048 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 4,125E-04 0,0135765 ! regulation of T cell proliferation GO:0042129 25 25 2,000 4,125E-04 0,01333831 ! negative regulation of immune system process GO:0002683 25 25 2,000 4,125E-04 0,01310834 ! axon extension GO:0048675 7 6 1,000 5,12E-04 0,0159926 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 1,000 5,12E-04 0,01572606 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of B cell proliferation GO:0030888 6 6 1,000 5,12E-04 0,01546825 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 5,12E-04 0,01521876 ! regulation of activated T cell proliferation GO:0046006 6 6 1,000 5,12E-04 0,0149772 ! pathogenesis GO:0009405 6 6 1,000 5,12E-04 0,01474318 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 5,12E-04 0,01451636 ! ER overload response GO:0006983 6 6 1,000 5,12E-04 0,01429641 ! focal adhesion formation GO:0048041 7 6 1,000 5,12E-04 0,01408303 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 5,12E-04 0,01387593 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 5,12E-04 0,01367483 ! genitalia development GO:0048806 6 6 1,000 5,12E-04 0,01347948 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 5,12E-04 0,01328962 ! multicellular organismal aging GO:0010259 6 6 1,000 5,12E-04 0,01310505 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 5,12E-04 0,01292552 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 5,203E-04 0,01295831 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 5,803E-04 0,01426069 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 5,992E-04 0,01452981 ! striated muscle tissue development GO:0014706 69 67 3,000 6,345E-04 0,01518628 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 6,446E-04 0,01523126 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of cell size GO:0008361 68 68 3,000 6,712E-04 0,01565951 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 7,095E-04 0,01634502 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 7,141E-04 0,01624694 ! regulation of mRNA processing GO:0050684 7 7 1,000 7,141E-04 0,01604881 ! cardiac muscle tissue development GO:0048738 7 7 1,000 7,141E-04 0,01585545 ! polyamine biosynthetic process GO:0006596 7 7 1,000 7,141E-04 0,0156667 ! response to X-ray GO:0010165 7 7 1,000 7,141E-04 0,01548238 ! regulation of intracellular pH GO:0051453 7 7 1,000 7,141E-04 0,01530235 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 1,000 7,141E-04 0,01512646 ! response to gamma radiation GO:0010332 8 7 1,000 7,141E-04 0,01495457 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 7,141E-04 0,01478654 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 7,141E-04 0,01462225 GO:0001953|negative regulation of cell-matrix adhesion, ! muscle tissue development GO:0060537 72 70 3,000 7,493E-04 0,0151748 ! B cell activation GO:0042113 31 31 2,000 7,865E-04 0,01575478 ! aging GO:0007568 32 31 2,000 7,865E-04 0,01558538 ! regulation of DNA replication GO:0006275 32 31 2,000 7,865E-04 0,01541957 ! regulation of intracellular transport GO:0032386 31 31 2,000 7,865E-04 0,01525726 ! regulation of cell migration GO:0030334 71 71 3,000 7,906E-04 0,01517789 ! negative regulation of cell growth GO:0030308 32 32 2,000 8,642E-04 0,01642046 ! negative regulation of cell size GO:0045792 33 33 2,000 9,467E-04 0,01780446 ! polyamine metabolic process GO:0006595 8 8 1,000 9,485E-04 0,01765706 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 9,485E-04 0,01748049 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 9,485E-04 0,01730742 ! immunoglobulin production during immune response GO:0002381 8 8 1,000 9,485E-04 0,01713774 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! T cell homeostasis GO:0043029 8 8 1,000 9,485E-04 0,01697135 ! regulation of protein catabolic process GO:0042176 35 34 2,000 1,034E-03 0,01832501 ! regulation of locomotion GO:0040012 79 79 3,000 1,181E-03 0,02073424 ! regulation of cell motion GO:0051270 79 79 3,000 1,181E-03 0,02053863 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,215E-03 0,02092537 ! pigmentation during development GO:0048066 9 9 1,000 1,215E-03 0,02073162 ! central nervous system neuron development GO:0021954 10 9 1,000 1,215E-03 0,02054142 ! regulation of cellular pH GO:0030641 9 9 1,000 1,215E-03 0,02035468 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 1,215E-03 0,0201713 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 1,000 1,215E-03 0,0199912 ! regulation of mitosis GO:0007088 37 36 2,000 1,224E-03 0,01995803 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 2,000 1,224E-03 0,01978296 ! lymphocyte activation GO:0046649 82 81 3,000 1,297E-03 0,02078368 ! negative regulation of growth GO:0045926 37 37 2,000 1,326E-03 0,02107014 ! urogenital system development GO:0001655 38 38 2,000 1,434E-03 0,02258717 ! axon guidance GO:0007411 39 38 2,000 1,434E-03 0,02239576 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 1,513E-03 0,02343038 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,513E-03 0,02323513 ! centrosome cycle GO:0007098 10 10 1,000 1,513E-03 0,0230431 ! induction of apoptosis via death domain receptors GO:0008625 10 10 1,000 1,513E-03 0,02285422 ! cell-substrate junction assembly GO:0007044 11 10 1,000 1,513E-03 0,02266842 ! central nervous system neuron differentiation GO:0021953 11 10 1,000 1,513E-03 0,02248561 ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 1,513E-03 0,02230572 ! neuromuscular junction development GO:0007528 10 10 1,000 1,513E-03 0,02212869 ! mismatch repair GO:0006298 10 10 1,000 1,513E-03 0,02195445 ! lymphocyte homeostasis GO:0002260 10 10 1,000 1,513E-03 0,02178293 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,513E-03 0,02161407 ! protein stabilization GO:0050821 10 10 1,000 1,513E-03 0,02144781 ! positive regulation of cell motion GO:0051272 39 39 2,000 1,547E-03 0,02176434 ! heart development GO:0007507 90 87 3,000 1,691E-03 0,02360946 ! positive regulation of hormone secretion GO:0046887 11 11 1,000 1,842E-03 0,02552612 ! dendrite development GO:0016358 11 11 1,000 1,842E-03 0,02533563 ! T cell proliferation GO:0042098 11 11 1,000 1,842E-03 0,02514796 ! activation of MAPKK activity GO:0000186 12 11 1,000 1,842E-03 0,02496305 ! cellular response to starvation GO:0009267 11 11 1,000 1,842E-03 0,02478084 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 1,842E-03 0,02460127 ! apoptotic nuclear changes GO:0030262 11 11 1,000 1,842E-03 0,02442428 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 1,842E-03 0,02424982 ! G1/S transition checkpoint GO:0031575 12 11 1,000 1,842E-03 0,02407783 ! somatic diversification of immunoglobulins GO:0016445 11 11 1,000 1,842E-03 0,02390827 ! mitochondrion organization GO:0007005 44 43 2,000 2,055E-03 0,0264828 ! homeostasis of number of cells GO:0048872 44 43 2,000 2,055E-03 0,02629889 ! protein import into nucleus GO:0006606 44 44 2,000 2,196E-03 0,02791319 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 2,202E-03 0,02779877 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 2,202E-03 0,02760966 ! microtubule organizing center organization GO:0031023 12 12 1,000 2,202E-03 0,02742311 GO:0051297|centrosome organization, ! regulation of insulin secretion GO:0050796 12 12 1,000 2,202E-03 0,02723906 ! regulation of chromosome organization GO:0033044 12 12 1,000 2,202E-03 0,02705747 ! G1 phase GO:0051318 13 12 1,000 2,202E-03 0,02687828 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 2,202E-03 0,02670145 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 2,202E-03 0,02652693 ! nuclear import GO:0051170 45 45 2,000 2,343E-03 0,02804329 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 2,496E-03 0,0296836 ! positive regulation of DNA replication GO:0045740 14 13 1,000 2,593E-03 0,03063132 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 1,000 2,593E-03 0,03043622 GO:0016444|somatic cell DNA recombination, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 2,593E-03 0,03024358 ! negative regulation of hormone secretion GO:0046888 13 13 1,000 2,593E-03 0,03005337 ! mitochondrial membrane organization GO:0007006 13 13 1,000 2,593E-03 0,02986554 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 2,593E-03 0,02968004 ! negative regulation of DNA replication GO:0008156 13 13 1,000 2,593E-03 0,02949683 ! actin filament bundle formation GO:0051017 13 13 1,000 2,593E-03 0,02931587 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 2,593E-03 0,02913711 ! cell aging GO:0007569 13 13 1,000 2,593E-03 0,02896052 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 2,593E-03 0,02878606 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 2,593E-03 0,02861369 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 2,593E-03 0,02844337 ! regulation of peptide secretion GO:0002791 13 13 1,000 2,593E-03 0,02827507 ! immunoglobulin production GO:0002377 13 13 1,000 2,593E-03 0,02810874 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 2,593E-03 0,02794436 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 2,593E-03 0,0277819 GO:0001952|regulation of cell-matrix adhesion, ! tissue homeostasis GO:0001894 13 13 1,000 2,593E-03 0,02762131 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 2,593E-03 0,02746256 ! sex differentiation GO:0007548 47 47 2,000 2,656E-03 0,02796823 ! regulation of catabolic process GO:0009894 48 47 2,000 2,656E-03 0,02780932 ! muscle organ development GO:0007517 102 100 3,000 2,817E-03 0,02933594 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 2,817E-03 0,02917113 ! hemopoiesis GO:0030097 104 100 3,000 2,817E-03 0,02900816 ! regulation of cell cycle process GO:0010564 50 48 2,000 2,821E-03 0,02888479 ! protein localization in nucleus GO:0034504 48 48 2,000 2,821E-03 0,02872521 ! DNA recombination GO:0006310 48 48 2,000 2,821E-03 0,02856738 ! gland development GO:0048732 51 49 2,000 2,993E-03 0,03013972 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 3,014E-03 0,0301843 ! base-excision repair GO:0006284 14 14 1,000 3,014E-03 0,03002115 ! negative regulation of transport GO:0051051 51 50 2,000 3,171E-03 0,03141666 ! T cell activation GO:0042110 51 50 2,000 3,171E-03 0,03124866 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 3,355E-03 0,03288933 GO:0051325|interphase, ! protein import into nucleus, translocation GO:0000060 15 15 1,000 3,464E-03 0,03377906 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 3,464E-03 0,03360128 ! striated muscle cell differentiation GO:0051146 16 15 1,000 3,464E-03 0,03342535 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 3,464E-03 0,03325126 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 3,464E-03 0,03307898 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 3,464E-03 0,03290847 ! response to starvation GO:0042594 15 15 1,000 3,464E-03 0,0327397 ! response to ionizing radiation GO:0010212 16 15 1,000 3,464E-03 0,03257266 ! leukocyte homeostasis GO:0001776 15 15 1,000 3,464E-03 0,03240732 ! glutathione metabolic process GO:0006749 16 15 1,000 3,464E-03 0,03224365 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 3,464E-03 0,03208162 ! somatic diversification of immune receptors GO:0002200 15 15 1,000 3,464E-03 0,03192121 ! cell fate commitment GO:0045165 52 52 2,000 3,546E-03 0,03251137 ! regulation of T cell activation GO:0050863 53 53 2,000 3,743E-03 0,03415052 ! regulation of protein transport GO:0051223 53 53 2,000 3,743E-03 0,03398229 GO:0070201|regulation of establishment of protein localization, ! positive regulation of mitosis GO:0045840 16 16 1,000 3,944E-03 0,03563151 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 3,944E-03 0,0354577 ! triglyceride metabolic process GO:0006641 16 16 1,000 3,944E-03 0,03528557 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 3,944E-03 0,03511511 ! lymphocyte proliferation GO:0046651 16 16 1,000 3,944E-03 0,03494629 ! cellular response to nutrient levels GO:0031669 16 16 1,000 3,944E-03 0,03477908 ! positive regulation of catabolic process GO:0009896 16 16 1,000 3,944E-03 0,03461347 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 3,947E-03 0,0344748 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 4,157E-03 0,03614264 ! regulation of cell adhesion GO:0030155 56 55 2,000 4,157E-03 0,03597296 ! reproductive developmental process GO:0003006 56 56 2,000 4,375E-03 0,03767616 ! extracellular structure organization GO:0043062 56 56 2,000 4,375E-03 0,03750093 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 1,000 4,453E-03 0,03799549 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 4,453E-03 0,03782039 ! myelination GO:0042552 17 17 1,000 4,453E-03 0,0376469 ! glucose transport GO:0015758 17 17 1,000 4,453E-03 0,037475 ! cell junction assembly GO:0034329 18 17 1,000 4,453E-03 0,03730466 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 4,453E-03 0,03713586 ! negative regulation of cell development GO:0010721 18 17 1,000 4,453E-03 0,03696858 GO:0050768|negative regulation of neurogenesis, ! pigmentation GO:0043473 17 17 1,000 4,453E-03 0,0368028 ! regulation of protein localization GO:0032880 58 57 2,000 4,599E-03 0,03783784 ! mononuclear cell proliferation GO:0032943 18 18 1,000 4,991E-03 0,04088087 GO:0070661|leukocyte proliferation, ! hexose transport GO:0008645 18 18 1,000 4,991E-03 0,04069998 GO:0015749|monosaccharide transport, ! neutral lipid metabolic process GO:0006638 18 18 1,000 4,991E-03 0,04052068 GO:0006639|acylglycerol metabolic process, ! B cell differentiation GO:0030183 18 18 1,000 4,991E-03 0,04034296 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 4,991E-03 0,04016679 ! ensheathment of neurons GO:0007272 18 18 1,000 4,991E-03 0,03999215 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 4,991E-03 0,03981902 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 4,991E-03 0,03964739 ! dephosphorylation GO:0016311 60 59 2,000 5,068E-03 0,04008432 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 5,068E-03 0,03991302 ! protein localization in organelle GO:0033365 59 59 2,000 5,068E-03 0,03974317 ! regulation of pH GO:0006885 19 19 1,000 5,557E-03 0,04339705 ! peripheral nervous system development GO:0007422 19 19 1,000 5,557E-03 0,04321394 ! biogenic amine biosynthetic process GO:0042401 20 19 1,000 5,557E-03 0,04303237 ! protein import GO:0017038 62 62 2,000 5,823E-03 0,04490482 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 5,823E-03 0,04471772 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 6,089E-03 0,04656697 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 6,151E-03 0,0468468 ! organic ether metabolic process GO:0018904 20 20 1,000 6,151E-03 0,04665401 GO:0006662|glycerol ether metabolic process, ! nucleus organization GO:0006997 20 20 1,000 6,151E-03 0,04646281 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 6,151E-03 0,04627316 ! regulation of B cell activation GO:0050864 20 20 1,000 6,151E-03 0,04608506 ! glycerolipid metabolic process GO:0046486 65 64 2,000 6,363E-03 0,04747483 ! angiogenesis GO:0001525 65 64 2,000 6,363E-03 0,0472834 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 6,773E-03 0,05013347 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 6,773E-03 0,04993294 ! mammary gland development GO:0030879 23 21 1,000 6,773E-03 0,049734 ! regulation of action potential in neuron GO:0019228 21 21 1,000 6,773E-03 0,04953664 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 6,773E-03 0,04934085 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 6,773E-03 0,04914659 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 6,773E-03 0,04895386 ! negative regulation of protein transport GO:0051224 21 21 1,000 6,773E-03 0,04876263 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 7,423E-03 0,05322963 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 7,423E-03 0,05302332 ! sister chromatid segregation GO:0000819 22 22 1,000 7,423E-03 0,05281859 ! odontogenesis GO:0042476 22 22 1,000 7,423E-03 0,05261544 ! cell junction organization GO:0034330 23 22 1,000 7,423E-03 0,05241385 ! hormone-mediated signaling GO:0009755 22 22 1,000 7,423E-03 0,0522138 ! spindle organization GO:0007051 22 22 1,000 7,423E-03 0,05201527 ! erythrocyte differentiation GO:0030218 23 22 1,000 7,423E-03 0,05181824 ! male sex differentiation GO:0046661 22 22 1,000 7,423E-03 0,0516227 ! neuron migration GO:0001764 22 22 1,000 7,423E-03 0,05142863 ! cytokinesis GO:0000910 23 22 1,000 7,423E-03 0,05123601 ! sensory perception of sound GO:0007605 71 69 2,000 7,839E-03 0,05390476 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 2,000 7,839E-03 0,05370437 ! regulation of hormone secretion GO:0046883 23 23 1,000 8,099E-03 0,05528391 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 8,099E-03 0,05507991 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 8,099E-03 0,05487741 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 8,099E-03 0,0546764 ! growth GO:0040007 70 70 2,000 8,156E-03 0,0548595 ! regulation of cell activation GO:0050865 71 71 2,000 8,481E-03 0,05683772 ! mitochondrial transport GO:0006839 24 24 1,000 8,802E-03 0,05877736 ! regulation of action potential GO:0001508 24 24 1,000 8,802E-03 0,05856516 ! glucose homeostasis GO:0042593 24 24 1,000 8,802E-03 0,0583545 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 8,802E-03 0,05814534 ! erythrocyte homeostasis GO:0034101 25 24 1,000 8,802E-03 0,05793768 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 8,802E-03 0,0577315 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 8,813E-03 0,05759988 ! negative regulation of secretion GO:0051048 26 25 1,000 9,532E-03 0,06207454 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 9,532E-03 0,06185597 ! cellular component disassembly GO:0022411 26 25 1,000 9,532E-03 0,06163893 ! endosome transport GO:0016197 25 25 1,000 9,532E-03 0,06142341 ! positive regulation of DNA binding GO:0043388 26 25 1,000 9,532E-03 0,06120939 ! positive regulation of binding GO:0051099 27 26 1,000 0,01028741 0,06583227 ! glycolysis GO:0006096 26 26 1,000 0,01028741 0,06560448 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01028741 0,06537826 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01028741 0,06515359 ! double-strand break repair GO:0006302 27 26 1,000 0,01028741 0,06493046 ! regulation of blood vessel size GO:0050880 27 26 1,000 0,01028741 0,06470886 GO:0035150|regulation of tube size, ! response to insulin stimulus GO:0032868 28 26 1,000 0,01028741 0,06448876 ! synapse organization GO:0050808 26 26 1,000 0,01028741 0,06427015 ! peptide metabolic process GO:0006518 29 27 1,000 0,01106878 0,0689181 ! activation of caspase activity GO:0006919 27 27 1,000 0,01106878 0,06868605 ! cell growth GO:0016049 27 27 1,000 0,01106878 0,06845556 ! nuclear transport GO:0051169 79 79 2,000 0,01135543 0,06999351 GO:0006913|nucleocytoplasmic transport, ! carbohydrate transport GO:0008643 28 28 1,000 0,01187558 0,07295565 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01187558 0,07271328 ! MAPKKK cascade GO:0000165 82 81 2,000 0,01215164 0,0741572 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,0127075 0,0772935 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,0127075 0,07703924 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 0,0127075 0,07678666 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,01297935 0,07817299 ! cellular amino acid derivative metabolic process GO:0006575 87 84 2,000 0,01340507 0,08047408 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01356423 0,0811652 GO:0043280|positive regulation of caspase activity, ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01356423 0,08090253 ! immunoglobulin mediated immune response GO:0016064 30 30 1,000 0,01356423 0,08064156 GO:0019724|B cell mediated immunity, ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 1,000 0,01356423 0,08038226 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01356423 0,08012462 ! regulation of cellular localization GO:0060341 86 85 2,000 0,01383874 0,08148497 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01444546 0,08478657 ! extracellular matrix organization GO:0030198 31 31 1,000 0,01444546 0,0845174 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,01444546 0,08424994 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,01444546 0,08398417 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01444546 0,08372007 ! muscle fiber development GO:0048747 32 32 1,000 0,01535087 0,0886886 ! glucose catabolic process GO:0006007 32 32 1,000 0,01535087 0,08841144 ! lipid modification GO:0030258 32 32 1,000 0,01535087 0,08813602 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01535087 0,0878623 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01535087 0,08759028 ! kidney development GO:0001822 32 32 1,000 0,01535087 0,08731994 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,01628017 0,09232111 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 0,01628017 0,09203791 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,01628017 0,09175645 ! DNA replication GO:0006260 91 91 2,000 0,0166087 0,09332269 ! regulation of actin filament length GO:0030832 34 34 1,000 0,01723305 0,09653654 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,01723305 0,096244 ! muscle cell differentiation GO:0042692 35 34 1,000 0,01723305 0,09595323 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,01723305 0,09566422 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,01723305 0,09537694 ! blood vessel development GO:0001568 95 94 2,000 0,0181024 0,09988837 ! regulation of cellular component size GO:0032535 35 35 1,000 0,01820922 0,10017788 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,01820922 0,09987973 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell growth GO:0001558 97 96 2,000 0,01913869 0,10466651 ! vasculature development GO:0001944 97 96 2,000 0,01913869 0,10435684 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,01920837 0,10442779 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,02020748 0,10953645 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,02023021 0,10933804 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 1,000 0,02023021 0,10901834 ! lung development GO:0030324 38 37 1,000 0,02023021 0,1087005 ! lymphocyte mediated immunity GO:0002449 37 37 1,000 0,02023021 0,10838451 ! adaptive immune response GO:0002250 37 37 1,000 0,02023021 0,10807035 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 1,000 0,02127445 0,11332024 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,02127445 0,11299367 ! chromosome segregation GO:0007059 38 38 1,000 0,02127445 0,11266897 ! hexose catabolic process GO:0019320 38 38 1,000 0,02127445 0,11234614 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,02127445 0,11202515 ! response to hormone stimulus GO:0009725 102 100 2,000 0,02130883 0,11188652 ! activation of MAPK activity GO:0000187 39 39 1,000 0,02234079 0,11697183 ! respiratory tube development GO:0030323 40 39 1,000 0,02234079 0,11664046 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,02234079 0,11631097 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,02234079 0,11598333 ! respiratory system development GO:0060541 40 39 1,000 0,02234079 0,11565754 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,02234079 0,11533356 ! protein oligomerization GO:0051259 39 39 1,000 0,02234079 0,1150114 ! DNA catabolic process GO:0006308 41 40 1,000 0,02342896 0,12027739 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,02342896 0,11994328 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,02342896 0,11961103 ! organelle localization GO:0051640 41 40 1,000 0,02342896 0,11928061 ! regulation of caspase activity GO:0043281 41 41 1,000 0,02453867 0,12458616 ! leukocyte mediated immunity GO:0002443 41 41 1,000 0,02453867 0,12424389 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,02453867 0,12390349 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,02566964 0,12925996 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,02566964 0,12890775 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,02566964 0,12855746 ! protein ubiquitination GO:0016567 43 42 1,000 0,02566964 0,12820906 ! forebrain development GO:0030900 43 42 1,000 0,02566964 0,12786255 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,02566964 0,12751791 ! reproductive structure development GO:0048608 43 43 1,000 0,02682158 0,13288219 ! alcohol catabolic process GO:0046164 43 43 1,000 0,02682158 0,13252594 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,02799422 0,13795014 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,02799422 0,13758227 ! amine biosynthetic process GO:0009309 46 45 1,000 0,02918729 0,1430643 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,02918729 0,14268482 ! regulation of DNA binding GO:0051101 47 45 1,000 0,02918729 0,14230734 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,02918729 0,14193186 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,02918729 0,14155836 ! rRNA transcription GO:0009303 5 5 0,000 0,02945195 0,14246704 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02945195 0,14209409 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02945195 0,14172309 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02945195 0,14135402 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02945195 0,14098687 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02945195 0,14062161 ! reproductive cellular process GO:0048610 5 5 0,000 0,02945195 0,14025825 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,02945195 0,13989676 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02945195 0,13953713 ! metencephalon development GO:0022037 5 5 0,000 0,02945195 0,13917934 ! water transport GO:0006833 5 5 0,000 0,02945195 0,13882338 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02945195 0,13846924 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02945195 0,1381169 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02945195 0,13776635 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02945195 0,13741758 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02945195 0,13707056 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02945195 0,1367253 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02945195 0,13638177 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02945195 0,13603996 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02945195 0,13569986 ! filopodium assembly GO:0046847 7 5 0,000 0,02945195 0,13536145 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02945195 0,13502473 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02945195 0,13468969 ! GTP metabolic process GO:0046039 5 5 0,000 0,02945195 0,1343563 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02945195 0,13402455 ! mRNA stabilization GO:0048255 5 5 0,000 0,02945195 0,13369444 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02945195 0,13336595 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02945195 0,13303908 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02945195 0,1327138 ! social behavior GO:0035176 5 5 0,000 0,02945195 0,13239011 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02945195 0,13206799 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02945195 0,13174743 ! memory GO:0007613 5 5 0,000 0,02945195 0,13142843 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02945195 0,13111097 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02945195 0,13079504 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02945195 0,13048063 ! response to lipid GO:0033993 5 5 0,000 0,02945195 0,13016773 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02945195 0,12985632 ! hippocampus development GO:0021766 6 5 0,000 0,02945195 0,1295464 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02945195 0,12923796 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02945195 0,12893098 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02945195 0,12862546 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02945195 0,12832138 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02945195 0,12801873 ! heart looping GO:0001947 5 5 0,000 0,02945195 0,12771751 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02945195 0,12741771 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02945195 0,1271193 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02945195 0,1268223 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02945195 0,12652667 ! pH reduction GO:0045851 5 5 0,000 0,02945195 0,12623243 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02945195 0,12593954 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02945195 0,12564802 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02945195 0,12535784 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02945195 0,12506899 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02945195 0,12478148 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02945195 0,12449528 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02945195 0,1242104 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02945195 0,12392681 ! adrenal gland development GO:0030325 5 5 0,000 0,02945195 0,12364452 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02945195 0,12336351 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02945195 0,12308377 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02945195 0,1228053 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02945195 0,12252809 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02945195 0,12225212 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02945195 0,1219774 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02945195 0,12170391 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02945195 0,12143164 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02945195 0,12116059 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02945195 0,12089074 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02945195 0,1206221 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02945195 0,12035464 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02945195 0,12008837 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02945195 0,11982327 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02945195 0,11955935 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02945195 0,11929658 ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02945195 0,11903496 ! response to ATP GO:0033198 5 5 0,000 0,02945195 0,11877449 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02945195 0,11851516 ! regulation of appetite GO:0032098 5 5 0,000 0,02945195 0,11825696 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02945195 0,11799988 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02945195 0,11774391 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,02945195 0,11748905 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02945195 0,1172353 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02945195 0,11698264 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02945195 0,11673106 ! receptor clustering GO:0043113 5 5 0,000 0,02945195 0,11648056 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02945195 0,11623114 ! fear response GO:0042596 5 5 0,000 0,02945195 0,11598278 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02945195 0,11573549 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02945195 0,11548924 ! retinol metabolic process GO:0042572 5 5 0,000 0,02945195 0,11524404 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02945195 0,11499988 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02945195 0,11475675 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02945195 0,11451465 ! parturition GO:0007567 5 5 0,000 0,02945195 0,11427356 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02945195 0,11403349 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02945195 0,11379443 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02945195 0,11355637 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02945195 0,1133193 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02945195 0,11308321 ! protein heterooligomerization GO:0051291 5 5 0,000 0,02945195 0,11284811 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02945195 0,11261399 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02945195 0,11238083 ! response to UV-B GO:0010224 5 5 0,000 0,02945195 0,11214864 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02945195 0,11191741 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02945195 0,11168713 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02945195 0,11145779 ! interaction with symbiont GO:0051702 5 5 0,000 0,02945195 0,11122939 ! cellular extravasation GO:0045123 5 5 0,000 0,02945195 0,11100193 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02945195 0,11077539 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02945195 0,11054978 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02945195 0,11032509 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02945195 0,1101013 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02945195 0,10987843 ! response to amine stimulus GO:0014075 5 5 0,000 0,02945195 0,10965645 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02945195 0,10943537 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02945195 0,10921518 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02945195 0,10899587 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02945195 0,10877744 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02945195 0,10855989 ! neuron recognition GO:0008038 5 5 0,000 0,02945195 0,1083432 ! decidualization GO:0046697 5 5 0,000 0,02945195 0,10812738 ! hair follicle maturation GO:0048820 5 5 0,000 0,02945195 0,10791241 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02945195 0,1076983 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02945195 0,10748504 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02945195 0,10727261 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02945195 0,10706103 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02945195 0,10685028 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02945195 0,10664036 ! postreplication repair GO:0006301 5 5 0,000 0,02945195 0,10643126 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02945195 0,10622298 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02945195 0,10601551 ! histone methylation GO:0016571 5 5 0,000 0,02945195 0,10580886 ! DNA methylation GO:0006306 5 5 0,000 0,02945195 0,105603 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02945195 0,10539795 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02945195 0,10519369 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02945195 0,10499022 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02945195 0,10478754 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02945195 0,10458563 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02945195 0,10438451 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02945195 0,10418415 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02945195 0,10398457 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02945195 0,10378574 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02945195 0,10358768 ! sterol catabolic process GO:0016127 5 5 0,000 0,02945195 0,10339037 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02945195 0,10319381 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02945195 0,10299799 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02945195 0,10280292 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02945195 0,10260859 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02945195 0,10241499 ! zymogen activation GO:0031638 5 5 0,000 0,02945195 0,10222212 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02945195 0,10202997 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02945195 0,10183854 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02945195 0,10164783 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,02945195 0,10145784 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02945195 0,10126855 ! nucleosome positioning GO:0016584 5 5 0,000 0,02945195 0,10107997 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02945195 0,10089209 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02945195 0,1007049 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02945195 0,10051841 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02945195 0,10033261 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02945195 0,1001475 ! NADPH regeneration GO:0006740 5 5 0,000 0,02945195 0,09996306 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02945195 0,09977931 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02945195 0,09959623 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02945195 0,09941382 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02945195 0,09923207 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02945195 0,09905099 ! sarcomere organization GO:0045214 5 5 0,000 0,02945195 0,09887057 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02945195 0,09869081 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02945195 0,09851169 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02945195 0,09833323 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02945195 0,09815541 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02945195 0,09797824 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02945195 0,0978017 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02945195 0,0976258 ! spleen development GO:0048536 5 5 0,000 0,02945195 0,09745053 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02945195 0,09727588 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02945195 0,09710187 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02945195 0,09692847 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02945195 0,09675569 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02945195 0,09658353 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02945195 0,09641198 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02945195 0,09624103 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02945195 0,0960707 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02945195 0,09590096 ! ATP catabolic process GO:0006200 5 5 0,000 0,02945195 0,09573182 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02945195 0,09556328 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02945195 0,09539533 ! blastocyst formation GO:0001825 5 5 0,000 0,02945195 0,09522797 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02945195 0,0950612 ! embryonic gut development GO:0048566 5 5 0,000 0,02945195 0,09489501 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02945195 0,09472939 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02945195 0,09456436 ! activation of innate immune response GO:0002218 5 5 0,000 0,02945195 0,0943999 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02945195 0,09423601 ! catecholamine transport GO:0051937 5 5 0,000 0,02945195 0,09407269 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02945195 0,09390994 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02945195 0,09374774 ! muscle adaptation GO:0043500 5 5 0,000 0,02945195 0,09358611 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02945195 0,09342503 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02945195 0,09326451 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02945195 0,09310453 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02945195 0,09294511 ! defense response to fungus GO:0050832 5 5 0,000 0,02945195 0,09278623 ! lysogeny GO:0030069 5 5 0,000 0,02945195 0,09262789 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02945195 0,09247009 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02945195 0,09231283 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02945195 0,0921561 ! response to nicotine GO:0035094 5 5 0,000 0,02945195 0,0919999 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02945195 0,09184424 ! mitochondrion localization GO:0051646 5 5 0,000 0,02945195 0,09168909 ! nucleus localization GO:0051647 5 5 0,000 0,02945195 0,09153447 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02945195 0,09138038 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,03040051 0,09416494 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,03040051 0,09400695 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,03040051 0,09384948 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,03040051 0,09369254 ! regulation of membrane potential GO:0042391 46 46 1,000 0,03040051 0,09353613 ! regulation of blood pressure GO:0008217 48 47 1,000 0,03163361 0,09716791 ! actin filament organization GO:0007015 50 48 1,000 0,03288633 0,10084777 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,03288633 0,10068025 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,03288633 0,10051328 ! leukocyte differentiation GO:0002521 50 49 1,000 0,0341584 0,10422836 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,0341584 0,10405609 GO:0060538|skeletal muscle organ development, ! regulation of ligase activity GO:0051340 50 49 1,000 0,0341584 0,10388438 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03523995 0,10699707 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03523995 0,10682108 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,03523995 0,10664568 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,03523995 0,10647085 ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03523995 0,10629659 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03523995 0,10612291 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03523995 0,10594979 ! virus-host interaction GO:0019048 6 6 0,000 0,03523995 0,10577723 ! regulation of S phase GO:0033261 6 6 0,000 0,03523995 0,10560523 ! myotube differentiation GO:0014902 6 6 0,000 0,03523995 0,1054338 ! bone remodeling GO:0046849 6 6 0,000 0,03523995 0,10526292 ! N-glycan processing GO:0006491 6 6 0,000 0,03523995 0,10509259 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03523995 0,10492281 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03523995 0,10475358 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03523995 0,10458489 ! RNA methylation GO:0001510 6 6 0,000 0,03523995 0,10441675 ! cartilage condensation GO:0001502 7 6 0,000 0,03523995 0,10424915 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,03523995 0,10408208 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,03523995 0,10391555 ! artery development GO:0060840 6 6 0,000 0,03523995 0,10374955 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03523995 0,10358408 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03523995 0,10341914 ! androgen metabolic process GO:0008209 6 6 0,000 0,03523995 0,10325472 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03523995 0,10309082 ! limbic system development GO:0021761 7 6 0,000 0,03523995 0,10292745 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03523995 0,10276459 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,03523995 0,10260224 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03523995 0,10244041 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03523995 0,10227909 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03523995 0,10211827 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03523995 0,10195796 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03523995 0,10179815 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03523995 0,10163884 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03523995 0,10148003 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03523995 0,10132171 ! arginine metabolic process GO:0006525 6 6 0,000 0,03523995 0,10116389 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03523995 0,10100656 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03523995 0,10084972 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03523995 0,10069336 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03523995 0,10053749 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03523995 0,1003821 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03523995 0,10022719 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03523995 0,10007276 ! V(D)J recombination GO:0033151 6 6 0,000 0,03523995 0,0999188 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03523995 0,09976531 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03523995 0,0996123 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03523995 0,09945975 ! regulation of heart rate GO:0002027 6 6 0,000 0,03523995 0,09930767 ! lipid digestion GO:0044241 6 6 0,000 0,03523995 0,09915606 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03523995 0,09900491 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03523995 0,09885421 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03523995 0,09870398 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03523995 0,0985542 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,03523995 0,09840488 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03523995 0,098256 ! ruffle organization GO:0031529 6 6 0,000 0,03523995 0,09810758 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,03523995 0,09795961 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03523995 0,09781208 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03523995 0,09766499 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03523995 0,09751835 ! L-amino acid transport GO:0015807 6 6 0,000 0,03523995 0,09737214 ! bone mineralization GO:0030282 6 6 0,000 0,03523995 0,09722638 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03523995 0,09708105 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03523995 0,09693615 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03523995 0,09679168 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,03523995 0,09664765 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03523995 0,09650404 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03523995 0,09636086 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03523995 0,0962181 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03523995 0,09607577 ! regulation of organ growth GO:0046620 6 6 0,000 0,03523995 0,09593385 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03523995 0,09579236 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03523995 0,09565128 ! response to dsRNA GO:0043331 6 6 0,000 0,03523995 0,09551062 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03523995 0,09537037 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03523995 0,09523053 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03523995 0,0950911 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03523995 0,09495207 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03523995 0,09481346 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03523995 0,09467525 ! erythrocyte development GO:0048821 6 6 0,000 0,03523995 0,09453744 ! renal water homeostasis GO:0003091 6 6 0,000 0,03523995 0,09440003 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03523995 0,09426302 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03523995 0,0941264 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03523995 0,09399019 ! ribosome assembly GO:0042255 6 6 0,000 0,03523995 0,09385436 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03523995 0,09371893 ! diencephalon development GO:0021536 6 6 0,000 0,03523995 0,09358389 ! fucose catabolic process GO:0019317 6 6 0,000 0,03523995 0,09344924 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03523995 0,09331497 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03523995 0,09318109 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03523995 0,09304759 ! regulation of cell division GO:0051302 6 6 0,000 0,03523995 0,09291448 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03523995 0,09278174 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03523995 0,09264939 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03523995 0,09251741 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03523995 0,0923858 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03523995 0,09225457 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03523995 0,09212372 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03523995 0,09199323 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03523995 0,09186311 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03523995 0,09173336 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03523995 0,09160398 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03523995 0,09147496 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03523995 0,0913463 ! thymus development GO:0048538 6 6 0,000 0,03523995 0,091218 ! lymph node development GO:0048535 6 6 0,000 0,03523995 0,09109007 ! organic cation transport GO:0015695 6 6 0,000 0,03523995 0,09096249 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03523995 0,09083527 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03523995 0,09070841 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,03523995 0,0905819 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03523995 0,09045574 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03523995 0,09032993 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03523995 0,09020447 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03523995 0,09007936 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03523995 0,0899546 ! alditol metabolic process GO:0019400 6 6 0,000 0,03523995 0,08983018 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03523995 0,0897061 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03523995 0,08958237 ! maternal placenta development GO:0001893 6 6 0,000 0,03523995 0,08945898 ! regulation of embryonic development GO:0045995 6 6 0,000 0,03523995 0,08933593 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03523995 0,08921321 ! localization within membrane GO:0051668 6 6 0,000 0,03523995 0,08909084 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,03544956 0,08949799 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,03544956 0,08937556 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,03544956 0,08925346 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,03675954 0,09242542 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,03675954 0,0922995 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,03808809 0,09550525 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,03943496 0,09874814 ! hormone metabolic process GO:0042445 55 54 1,000 0,04079988 0,10202739 ! sulfur metabolic process GO:0006790 55 54 1,000 0,04079988 0,10188914 ! respiratory burst GO:0045730 7 7 0,000 0,04099426 0,10223602 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04099426 0,10209787 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04099426 0,10196008 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04099426 0,10182267 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04099426 0,10168563 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04099426 0,10154895 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04099426 0,10141265 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04099426 0,10127671 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04099426 0,10114113 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04099426 0,10100591 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04099426 0,10087106 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04099426 0,10073656 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04099426 0,10060243 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04099426 0,10046865 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04099426 0,10033522 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04099426 0,10020215 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04099426 0,10006943 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04099426 0,09993707 ! axis specification GO:0009798 7 7 0,000 0,04099426 0,09980505 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04099426 0,09967338 ! visual behavior GO:0007632 7 7 0,000 0,04099426 0,09954206 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04099426 0,09941108 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04099426 0,09928045 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04099426 0,09915016 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04099426 0,09902021 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04099426 0,0988906 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04099426 0,09876134 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04099426 0,0986324 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04099426 0,09850381 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04099426 0,09837555 ! digestive system development GO:0055123 7 7 0,000 0,04099426 0,09824762 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04099426 0,09812003 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04099426 0,09799277 ! protein targeting to ER GO:0045047 8 7 0,000 0,04099426 0,09786583 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04099426 0,09773923 ! endoderm development GO:0007492 7 7 0,000 0,04099426 0,09761295 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04099426 0,097487 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04099426 0,09736137 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04099426 0,09723606 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04099426 0,09711108 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04099426 0,09698642 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04099426 0,09686208 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04099426 0,09673806 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04099426 0,09661435 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04099426 0,09649096 GO:0032309|icosanoid secretion, ! UV protection GO:0009650 7 7 0,000 0,04099426 0,09636789 ! DNA integration GO:0015074 7 7 0,000 0,04099426 0,09624512 ! myofibril assembly GO:0030239 7 7 0,000 0,04099426 0,09612267 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04099426 0,09600054 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04099426 0,09587871 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04099426 0,09575719 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04099426 0,09563598 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04099426 0,09551507 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04099426 0,09539447 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04099426 0,09527418 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04099426 0,09515418 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04099426 0,09503449 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04099426 0,0949151 ! axon cargo transport GO:0008088 7 7 0,000 0,04099426 0,09479601 ! eating behavior GO:0042755 7 7 0,000 0,04099426 0,09467722 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04099426 0,09455873 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04099426 0,09444053 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04099426 0,09432262 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04099426 0,09420501 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04099426 0,0940877 ! cranial nerve development GO:0021545 7 7 0,000 0,04099426 0,09397067 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04099426 0,09385394 ! induction of an organ GO:0001759 7 7 0,000 0,04099426 0,0937375 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04099426 0,09362134 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04099426 0,09350547 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04099426 0,09338989 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04099426 0,0932746 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04099426 0,09315958 ! platelet activation GO:0030168 8 7 0,000 0,04099426 0,09304485 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04099426 0,09293041 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04099426 0,09281624 ! natural killer cell activation GO:0030101 7 7 0,000 0,04099426 0,09270236 ! NADP metabolic process GO:0006739 7 7 0,000 0,04099426 0,09258875 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04099426 0,09247542 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04099426 0,09236237 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04099426 0,0922496 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04099426 0,0921371 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04099426 0,09202487 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04099426 0,09191292 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04099426 0,09180124 ! cell-cell recognition GO:0009988 8 7 0,000 0,04099426 0,09168983 ! hormone catabolic process GO:0042447 7 7 0,000 0,04099426 0,09157869 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04099426 0,09146782 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04099426 0,09135722 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04099426 0,09124689 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,04099426 0,09113682 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04099426 0,09102701 ! regulation of axon extension GO:0030516 7 7 0,000 0,04099426 0,09091748 ! cell killing GO:0001906 7 7 0,000 0,04099426 0,0908082 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04099426 0,09069919 ! adult feeding behavior GO:0008343 7 7 0,000 0,04099426 0,09059043 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04099426 0,09048194 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04099426 0,09037371 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04099426 0,09026574 ! response to cold GO:0009409 7 7 0,000 0,04099426 0,09015802 ! in utero embryonic development GO:0001701 55 55 1,000 0,04218261 0,09266098 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,04218261 0,09255066 ! regulation of nervous system development GO:0051960 57 56 1,000 0,04358291 0,09550927 ! regulation of binding GO:0051098 60 57 1,000 0,04500051 0,09849873 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04671509 0,10213037 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04671509 0,10200936 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04671509 0,10188864 ! positive regulation of translation GO:0045727 8 8 0,000 0,04671509 0,10176821 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04671509 0,10164806 ! superoxide anion generation GO:0042554 8 8 0,000 0,04671509 0,10152819 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04671509 0,1014086 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04671509 0,1012893 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04671509 0,10117027 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04671509 0,10105153 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04671509 0,10093306 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04671509 0,10081488 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,04671509 0,10069696 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04671509 0,10057933 ! zinc ion transport GO:0006829 8 8 0,000 0,04671509 0,10046196 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04671509 0,10034488 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04671509 0,10022806 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04671509 0,10011152 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04671509 0,09999524 ! lipid localization GO:0010876 8 8 0,000 0,04671509 0,09987924 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04671509 0,0997635 ! response to cAMP GO:0051591 8 8 0,000 0,04671509 0,09964804 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04671509 0,09953284 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04671509 0,0994179 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04671509 0,09930323 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04671509 0,09918883 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04671509 0,09907469 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04671509 0,09896081 ! sensory perception of taste GO:0050909 8 8 0,000 0,04671509 0,09884719 ! organelle fusion GO:0048284 8 8 0,000 0,04671509 0,09873383 ! pancreas development GO:0031016 8 8 0,000 0,04671509 0,09862074 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04671509 0,0985079 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,04671509 0,09839532 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04671509 0,098283 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04671509 0,09817093 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04671509 0,09805912 ! sperm motility GO:0030317 8 8 0,000 0,04671509 0,09794756 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04671509 0,09783625 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04671509 0,0977252 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04671509 0,0976144 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04671509 0,09750385 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04671509 0,09739356 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04671509 0,09728351 GO:0006600|creatine metabolic process, ! Golgi organization GO:0007030 8 8 0,000 0,04671509 0,09717371 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04671509 0,09706415 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04671509 0,09695485 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,04671509 0,09684579 ! fructose metabolic process GO:0006000 8 8 0,000 0,04671509 0,09673697 ! mannose metabolic process GO:0006013 9 8 0,000 0,04671509 0,0966284 ! NAD metabolic process GO:0019674 8 8 0,000 0,04671509 0,09652007 ! sex determination GO:0007530 8 8 0,000 0,04671509 0,09641199 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04671509 0,09630414 ! plasma membrane fusion GO:0045026 8 8 0,000 0,04671509 0,09619654 ! response to fungus GO:0009620 8 8 0,000 0,04671509 0,09608918 ! stem cell differentiation GO:0048863 8 8 0,000 0,04671509 0,09598206 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04671509 0,09587517 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04671509 0,09576852 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04671509 0,09566212 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04671509 0,09555594 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04671509 0,09545 ! vasoconstriction GO:0042310 8 8 0,000 0,04671509 0,0953443 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04671509 0,09523883 ! muscle cell development GO:0055001 8 8 0,000 0,04671509 0,0951336 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04671509 0,09502859 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04671509 0,09492382 ! sensory perception of pain GO:0019233 8 8 0,000 0,04671509 0,09481928 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04671509 0,09471497 ! mRNA cleavage GO:0006379 8 8 0,000 0,04671509 0,09461088 ! chromatin silencing GO:0006342 8 8 0,000 0,04671509 0,09450703 ! tissue regeneration GO:0042246 8 8 0,000 0,04671509 0,0944034 ! salivary gland development GO:0007431 8 8 0,000 0,04671509 0,0943 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04671509 0,09419683 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04671509 0,09409388 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,04671509 0,09399116 ! water homeostasis GO:0030104 8 8 0,000 0,04671509 0,09388866 ! cofactor transport GO:0051181 8 8 0,000 0,04671509 0,09378639 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04671509 0,09368433 ! acid secretion GO:0046717 8 8 0,000 0,04671509 0,0935825 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,04671509 0,09348089 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04671509 0,09337951 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04671509 0,09327834 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04671509 0,09317739 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04671509 0,09307665 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04671509 0,09297614 ! regulation of RNA stability GO:0043487 8 8 0,000 0,04671509 0,09287584 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04671509 0,09277576 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,04671509 0,09267589 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04671509 0,09257624 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04671509 0,0924768 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04671509 0,09237758 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04671509 0,09227857 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04671509 0,09217977 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04671509 0,09208118 ! developmental induction GO:0031128 8 8 0,000 0,04671509 0,0919828 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04671509 0,09188464 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04671509 0,09178668 ! actin filament polymerization GO:0030041 9 8 0,000 0,04671509 0,09168893 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,04671509 0,09159139 ! peptide hormone processing GO:0016486 8 8 0,000 0,04671509 0,09149405 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04671509 0,09139693 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04671509 0,0913 ! regulation of cell development GO:0060284 60 59 1,000 0,04788667 0,0934906 ! immune effector process GO:0002252 59 59 1,000 0,04788667 0,09339167 ! protein polymerization GO:0051258 65 60 1,000 0,04935474 0,09615306 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,05083917 0,09894043 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,05083917 0,09883606 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,0523397 0,10164601 ! lactation GO:0007595 10 9 0,000 0,05240261 0,10166107 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05240261 0,10155417 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05240261 0,10144749 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,05240261 0,10134104 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05240261 0,10123482 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05240261 0,10112881 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05240261 0,10102303 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,05240261 0,10091747 ! viral genome replication GO:0019079 9 9 0,000 0,05240261 0,10081212 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05240261 0,100707 ! copper ion transport GO:0006825 9 9 0,000 0,05240261 0,1006021 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05240261 0,10049741 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05240261 0,10039295 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05240261 0,1002887 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05240261 0,10018466 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05240261 0,10008084 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05240261 0,09997724 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05240261 0,09987385 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,05240261 0,09977068 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05240261 0,09966771 ! phospholipid efflux GO:0033700 9 9 0,000 0,05240261 0,09956496 ! response to alkaloid GO:0043279 10 9 0,000 0,05240261 0,09946243 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05240261 0,0993601 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05240261 0,09925798 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,05240261 0,09915607 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05240261 0,09905437 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05240261 0,09895288 ! response to ethanol GO:0045471 9 9 0,000 0,05240261 0,0988516 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05240261 0,09875053 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,05240261 0,09864966 ! methionine metabolic process GO:0006555 9 9 0,000 0,05240261 0,09854899 ! glutamine metabolic process GO:0006541 9 9 0,000 0,05240261 0,09844854 ! cerebral cortex development GO:0021987 9 9 0,000 0,05240261 0,09834828 ! response to osmotic stress GO:0006970 9 9 0,000 0,05240261 0,09824823 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05240261 0,09814839 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05240261 0,09804875 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,05240261 0,09794931 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05240261 0,09785007 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05240261 0,09775103 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05240261 0,09765219 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,05240261 0,09755355 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,05240261 0,09745511 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,05240261 0,09735687 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,05240261 0,09725883 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05240261 0,09716098 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05240261 0,09706333 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05240261 0,09696588 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05240261 0,09686862 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,05240261 0,09677156 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,05240261 0,09667469 ! DNA replication initiation GO:0006270 9 9 0,000 0,05240261 0,09657801 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05240261 0,09648153 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,05240261 0,09638524 ! histone acetylation GO:0016573 9 9 0,000 0,05240261 0,09628915 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05240261 0,09619324 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05240261 0,09609753 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05240261 0,096002 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05240261 0,09590667 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05240261 0,09581152 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,05240261 0,09571657 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05240261 0,0956218 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,05240261 0,09552722 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05240261 0,09543282 ! collagen catabolic process GO:0030574 9 9 0,000 0,05240261 0,09533861 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05240261 0,09524459 ! purine base metabolic process GO:0006144 9 9 0,000 0,05240261 0,09515075 ! cholesterol efflux GO:0033344 9 9 0,000 0,05240261 0,0950571 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05240261 0,09496363 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05240261 0,09487035 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05240261 0,09477725 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,05240261 0,09468433 ! defense response to virus GO:0051607 9 9 0,000 0,05240261 0,09459159 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05240261 0,09449904 ! actin filament-based movement GO:0030048 9 9 0,000 0,05240261 0,09440666 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05240261 0,09431447 ! regulation of secretion GO:0051046 65 63 1,000 0,0538561 0,0968359 ! glucose metabolic process GO:0006006 63 63 1,000 0,0538561 0,09674152 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,05538815 0,09939665 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,05538815 0,09929996 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,05693561 0,10197506 ! regulation of hormone levels GO:0010817 66 65 1,000 0,05693561 0,10187605 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,05805703 0,10378187 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,05805703 0,1036813 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,05805703 0,10358093 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,05805703 0,10348076 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,05805703 0,10338078 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,05805703 0,10328099 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,05805703 0,10318139 ! neuron maturation GO:0042551 10 10 0,000 0,05805703 0,10308199 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,05805703 0,10298278 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,05805703 0,10288375 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,05805703 0,10278492 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,05805703 0,10268628 ! hormone secretion GO:0046879 10 10 0,000 0,05805703 0,10258783 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,05805703 0,10248956 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,05805703 0,10239149 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! cAMP metabolic process GO:0046058 10 10 0,000 0,05805703 0,1022936 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,05805703 0,1021959 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,05805703 0,10209838 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,05805703 0,10200105 ! glial cell development GO:0021782 10 10 0,000 0,05805703 0,10190391 ! phototransduction GO:0007602 11 10 0,000 0,05805703 0,10180695 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,05805703 0,10171017 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,05805703 0,10161358 ! fat cell differentiation GO:0045444 10 10 0,000 0,05805703 0,10151718 ! myoblast differentiation GO:0045445 10 10 0,000 0,05805703 0,10142095 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,05805703 0,10132491 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,05805703 0,10122905 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,05805703 0,10113337 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,05805703 0,10103787 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,05805703 0,10094255 ! protein polyubiquitination GO:0000209 10 10 0,000 0,05805703 0,10084741 ! glutamate metabolic process GO:0006536 11 10 0,000 0,05805703 0,10075245 ! plasma membrane organization GO:0007009 10 10 0,000 0,05805703 0,10065767 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,05805703 0,10056307 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,05805703 0,10046864 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,05805703 0,10037439 GO:0030968|endoplasmic reticulum unfolded protein response, ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,05805703 0,10028032 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,05805703 0,10018643 ! exocrine system development GO:0035272 10 10 0,000 0,05805703 0,10009271 ! embryo implantation GO:0007566 11 10 0,000 0,05805703 0,09999916 ! regulation of protein binding GO:0043393 11 10 0,000 0,05805703 0,09990579 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,05805703 0,0998126 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,05805703 0,09971957 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,05805703 0,09962673 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,05805703 0,09953405 ! protein export from nucleus GO:0006611 10 10 0,000 0,05805703 0,09944155 ! negative regulation of immune response GO:0050777 10 10 0,000 0,05805703 0,09934921 ! cytolysis GO:0019835 10 10 0,000 0,05805703 0,09925705 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,05805703 0,09916506 GO:0030501|positive regulation of bone mineralization, ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,05805703 0,09907324 ! histone deacetylation GO:0016575 10 10 0,000 0,05805703 0,09898159 ! mRNA splice site selection GO:0006376 11 10 0,000 0,05805703 0,09889011 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,05805703 0,0987988 ! gland morphogenesis GO:0022612 10 10 0,000 0,05805703 0,09870766 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,05805703 0,09861669 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,05805703 0,09852588 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,05805703 0,09843524 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,05805703 0,09834476 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,05805703 0,09825446 ! regulation of epidermis development GO:0045682 10 10 0,000 0,05805703 0,09816432 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,05805703 0,09807434 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,05805703 0,09798453 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,05805703 0,09789488 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,05805703 0,0978054 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,05805703 0,09771608 ! nerve development GO:0021675 10 10 0,000 0,05805703 0,09762692 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,05805703 0,09753793 ! gut development GO:0048565 10 10 0,000 0,05805703 0,09744909 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,05805703 0,09736042 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,05805703 0,09727191 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,05805703 0,09718356 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,05805703 0,09709538 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,05805703 0,09700735 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,05849826 0,09765606 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,06007586 0,10019893 ! response to nutrient levels GO:0031667 69 69 1,000 0,06327506 0,10543936 ! protein secretion GO:0009306 11 11 0,000 0,06367852 0,10601582 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06367852 0,10592014 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,06367852 0,10582463 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,06367852 0,10572929 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06367852 0,10563413 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,06367852 0,10553913 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06367852 0,10544431 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,06367852 0,10534966 ! skin development GO:0043588 11 11 0,000 0,06367852 0,10525517 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06367852 0,10516086 ! signal complex assembly GO:0007172 11 11 0,000 0,06367852 0,10506671 ! microtubule-based transport GO:0010970 11 11 0,000 0,06367852 0,10497273 ! peroxisomal transport GO:0043574 11 11 0,000 0,06367852 0,10487892 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06367852 0,10478528 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,06367852 0,10469181 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,06367852 0,1045985 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,06367852 0,10450536 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,06367852 0,10441238 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,06367852 0,10431957 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,06367852 0,10422692 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,06367852 0,10413444 ! spinal cord development GO:0021510 11 11 0,000 0,06367852 0,10404212 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06367852 0,10394997 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,06367852 0,10385798 ! digestive system process GO:0022600 11 11 0,000 0,06367852 0,10376615 ! mitotic spindle organization GO:0007052 11 11 0,000 0,06367852 0,10367448 ! fucose metabolic process GO:0006004 11 11 0,000 0,06367852 0,10358298 ! membrane budding GO:0006900 11 11 0,000 0,06367852 0,10349164 ! monoamine transport GO:0015844 11 11 0,000 0,06367852 0,10340046 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06367852 0,10330943 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,06367852 0,10321857 ! body fluid secretion GO:0007589 11 11 0,000 0,06367852 0,10312787 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,06367852 0,10303733 ! intermediate filament-based process GO:0045103 11 11 0,000 0,06367852 0,10294694 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06367852 0,10285672 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,06367852 0,10276665 ! membrane depolarization GO:0051899 11 11 0,000 0,06367852 0,10267674 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,06367852 0,10258699 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06367852 0,10249739 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,06367852 0,10240796 ! oogenesis GO:0048477 11 11 0,000 0,06367852 0,10231867 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,06367852 0,10222954 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06367852 0,10214057 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,06367852 0,10205175 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,06367852 0,10196309 ! muscle maintenance GO:0046716 12 11 0,000 0,06367852 0,10187458 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,06367852 0,10178622 ! hindbrain development GO:0030902 11 11 0,000 0,06367852 0,10169802 ! steroid catabolic process GO:0006706 11 11 0,000 0,06367852 0,10160997 ! endocrine process GO:0050886 11 11 0,000 0,06367852 0,10152207 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,06367852 0,10143433 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,06367852 0,10134673 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06367852 0,10125929 ! positive regulation of transport GO:0051050 71 70 1,000 0,06489621 0,10310665 ! wound healing GO:0042060 74 70 1,000 0,06489621 0,10301784 ! translational elongation GO:0006414 71 71 1,000 0,06653143 0,10552275 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,06653143 0,10543201 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,06818052 0,10795249 ! translational initiation GO:0006413 12 12 0,000 0,06926728 0,10957905 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,06926728 0,10948508 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06926728 0,10939126 ! initiation of viral infection GO:0019059 12 12 0,000 0,06926728 0,1092976 ! iron ion transport GO:0006826 13 12 0,000 0,06926728 0,1092041 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06926728 0,10911077 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06926728 0,10901759 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06926728 0,10892457 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,06926728 0,10883171 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06926728 0,10873901 ! collagen metabolic process GO:0032963 12 12 0,000 0,06926728 0,10864647 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06926728 0,10855408 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06926728 0,10846185 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06926728 0,10836978 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06926728 0,10827786 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06926728 0,1081861 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06926728 0,10809449 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,06926728 0,10800304 ! actomyosin structure organization GO:0031032 12 12 0,000 0,06926728 0,10791175 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,06926728 0,10782061 ! retinoid metabolic process GO:0001523 12 12 0,000 0,06926728 0,10772962 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06926728 0,10763878 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06926728 0,1075481 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06926728 0,10745757 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06926728 0,1073672 ! acute-phase response GO:0006953 12 12 0,000 0,06926728 0,10727697 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06926728 0,1071869 ! vacuolar transport GO:0007034 12 12 0,000 0,06926728 0,10709698 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06926728 0,10700721 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06926728 0,10691759 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06926728 0,10682812 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06926728 0,10673879 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,06926728 0,10664962 ! male gonad development GO:0008584 12 12 0,000 0,06926728 0,1065606 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06926728 0,10647172 ! renal system process GO:0003014 12 12 0,000 0,06926728 0,106383 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06926728 0,10629442 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06926728 0,10620599 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,06926728 0,1061177 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06926728 0,10602957 ! pallium development GO:0021543 13 12 0,000 0,06926728 0,10594158 ! cell fate determination GO:0001709 12 12 0,000 0,06926728 0,10585373 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,06926728 0,10576603 ! somitogenesis GO:0001756 13 12 0,000 0,06926728 0,10567848 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06926728 0,10559107 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06926728 0,1055038 ! detection of light stimulus GO:0009583 13 12 0,000 0,06926728 0,10541668 ! synaptogenesis GO:0007416 12 12 0,000 0,06926728 0,1053297 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06926728 0,10524287 ! hormone transport GO:0009914 12 12 0,000 0,06926728 0,10515618 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06926728 0,10506963 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06926728 0,10498322 ! spermatid differentiation GO:0048515 13 12 0,000 0,06926728 0,10489696 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06926728 0,10481084 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06926728 0,10472485 ! neural tube closure GO:0001843 13 12 0,000 0,06926728 0,10463901 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,06926728 0,10455332 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,06926728 0,10446776 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,07151942 0,1077762 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,07482349 0,11266315 ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,07482349 0,11257118 ! phenol metabolic process GO:0018958 13 13 0,000 0,07482349 0,11247936 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,07482349 0,11238769 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,07482349 0,11229617 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,07482349 0,11220479 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,07482349 0,11211357 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,07482349 0,11202249 ! regeneration GO:0031099 13 13 0,000 0,07482349 0,11193157 ! keratinization GO:0031424 13 13 0,000 0,07482349 0,11184079 ! post-embryonic development GO:0009791 14 13 0,000 0,07482349 0,11175015 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,07482349 0,11165967 ! patterning of blood vessels GO:0001569 13 13 0,000 0,07482349 0,11156933 ! vasculogenesis GO:0001570 13 13 0,000 0,07482349 0,11147914 ! regulation of innate immune response GO:0045088 13 13 0,000 0,07482349 0,11138909 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,07482349 0,11129919 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,07482349 0,11120943 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,07482349 0,11111982 ! autophagy GO:0006914 13 13 0,000 0,07482349 0,11103035 ! receptor metabolic process GO:0043112 14 13 0,000 0,07482349 0,11094102 ! ureteric bud development GO:0001657 13 13 0,000 0,07482349 0,11085184 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,07482349 0,1107628 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,07482349 0,11067391 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,07482349 0,11058516 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 13 13 0,000 0,07482349 0,11049655 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,07482349 0,11040808 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,07482349 0,11031975 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,07482349 0,11023157 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,07482349 0,11014352 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,07482349 0,11005562 ! vasodilation GO:0042311 14 13 0,000 0,07482349 0,10996786 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,07482349 0,10988023 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,07482349 0,10979275 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,07482349 0,1097054 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,07482349 0,1096182 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,07482349 0,10953113 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,07482349 0,1094442 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,07482349 0,10935741 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,07482349 0,10927075 ! cell-cell junction organization GO:0045216 13 13 0,000 0,07482349 0,10918424 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,07482349 0,10909786 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,07482349 0,10901161 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,07482349 0,10892551 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,07482349 0,10883954 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,07482349 0,1087537 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,07482349 0,108668 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,07482349 0,10858243 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,07482349 0,108497 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,07482349 0,10841171 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,07482349 0,10832654 ! blastocyst development GO:0001824 13 13 0,000 0,07482349 0,10824152 ! telomere organization GO:0032200 13 13 0,000 0,07482349 0,10815662 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,07482349 0,10807186 ! regulation of amine transport GO:0051952 13 13 0,000 0,07482349 0,10798723 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,07482349 0,10790273 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,07491122 0,10794478 ! regulation of protein modification process GO:0031399 79 78 1,000 0,07835426 0,1128179 ! microtubule-based movement GO:0007018 82 78 1,000 0,07835426 0,11272983 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,07835426 0,11264189 ! neuron fate commitment GO:0048663 14 14 0,000 0,08034733 0,1154171 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,08034733 0,11532721 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,08034733 0,11523746 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,08034733 0,11514785 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,08034733 0,11505838 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,08034733 0,11496905 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,08034733 0,11487986 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,08034733 0,1147908 ! protein amino acid acylation GO:0043543 14 14 0,000 0,08034733 0,11470189 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,08034733 0,11461311 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,08034733 0,11452447 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,08034733 0,11443596 ! vesicle docking GO:0048278 14 14 0,000 0,08034733 0,11434759 ! superoxide metabolic process GO:0006801 15 14 0,000 0,08034733 0,11425936 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,08034733 0,11417127 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,08034733 0,11408331 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,08034733 0,11399549 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,08034733 0,1139078 ! hair cycle GO:0042633 14 14 0,000 0,08034733 0,11382024 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,08034733 0,11373282 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,08034733 0,11364554 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,08034733 0,11355839 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,08034733 0,11347137 ! lysosome organization GO:0007040 14 14 0,000 0,08034733 0,11338448 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,08034733 0,11329773 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,08034733 0,11321111 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,08034733 0,11312463 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,08034733 0,11303827 ! primary neural tube formation GO:0014020 15 14 0,000 0,08034733 0,11295205 ! peptide cross-linking GO:0018149 14 14 0,000 0,08034733 0,11286596 ! regulation of behavior GO:0050795 14 14 0,000 0,08034733 0,11278 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,08034733 0,11269417 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,08034733 0,11260847 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,08034733 0,1125229 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,08034733 0,11243746 ! formation of primary germ layer GO:0001704 14 14 0,000 0,08034733 0,11235215 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,08034733 0,11226697 ! collagen fibril organization GO:0030199 14 14 0,000 0,08034733 0,11218192 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,08034733 0,112097 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,08034733 0,11201221 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,08034733 0,11192754 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,08034733 0,111843 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,08034733 0,11175859 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,08034733 0,11167431 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,08034733 0,11159015 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,08034733 0,11150613 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,08034733 0,11142222 ! tube development GO:0035295 83 81 1,000 0,08361136 0,11586146 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,085839 0,11885896 ! positive regulation of ossification GO:0045778 15 15 0,000 0,085839 0,11876972 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,085839 0,11868062 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,085839 0,11859166 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,085839 0,11850282 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,085839 0,11841412 ! response to vitamin GO:0033273 15 15 0,000 0,085839 0,11832556 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,085839 0,11823712 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,085839 0,11814882 ! ovarian follicle development GO:0001541 15 15 0,000 0,085839 0,11806065 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,085839 0,11797261 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,085839 0,1178847 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,085839 0,11779693 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,085839 0,11770928 ! heme metabolic process GO:0042168 15 15 0,000 0,085839 0,11762176 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,085839 0,11753438 ! chromosome condensation GO:0030261 15 15 0,000 0,085839 0,11744712 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,085839 0,11735999 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,085839 0,117273 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,085839 0,11718613 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,085839 0,11709939 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,085839 0,11701277 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,085839 0,11692629 ! phospholipid transport GO:0015914 15 15 0,000 0,085839 0,11683993 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,085839 0,11675371 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,085839 0,1166676 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,085839 0,11658163 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,085839 0,11649578 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,085839 0,11641006 GO:0090048|negative regulation of transcription regulator activity, ! protein homooligomerization GO:0051260 15 15 0,000 0,085839 0,11632446 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,085839 0,11623899 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,09078525 0,12284671 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,09078525 0,12275658 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,09129866 0,12336029 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,09129866 0,12326991 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,09129866 0,12317967 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,09129866 0,12308956 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,09129866 0,12299959 ! learning GO:0007612 16 16 0,000 0,09129866 0,12290974 ! circadian rhythm GO:0007623 16 16 0,000 0,09129866 0,12282002 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,09129866 0,12273044 ! vacuole organization GO:0007033 16 16 0,000 0,09129866 0,12264099 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,09129866 0,12255166 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,09129866 0,12246247 ! vesicle targeting GO:0006903 17 16 0,000 0,09129866 0,12237341 ! segmentation GO:0035282 17 16 0,000 0,09129866 0,12228447 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,09129866 0,12219567 ! iron ion homeostasis GO:0055072 16 16 0,000 0,09129866 0,12210699 ! positive regulation of cell development GO:0010720 16 16 0,000 0,09129866 0,12201844 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,09129866 0,12193002 ! cell fate specification GO:0001708 16 16 0,000 0,09129866 0,12184173 ! pentose metabolic process GO:0019321 16 16 0,000 0,09129866 0,12175357 ! fatty acid transport GO:0015908 16 16 0,000 0,09129866 0,12166553 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,09129866 0,12157763 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,09129866 0,12148984 ! cofactor catabolic process GO:0051187 16 16 0,000 0,09129866 0,12140219 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,09129866 0,12131466 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,09129866 0,12122726 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,09129866 0,12113998 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,09129866 0,12105283 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,09129866 0,1209658 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,09129866 0,1208789 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,09129866 0,12079213 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,09129866 0,12070548 ! regulation of coagulation GO:0050818 17 16 0,000 0,09129866 0,12061895 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,0926068 0,12225955 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,0926068 0,12217203 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 1,000 0,0926068 0,12208464 ! male gamete generation GO:0048232 90 88 1,000 0,09628225 0,12683931 GO:0007283|spermatogenesis, ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,09672651 0,12733354 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,09672651 0,12724265 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,09672651 0,1271519 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,09672651 0,12706127 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,09672651 0,12697077 ! leukocyte adhesion GO:0007159 17 17 0,000 0,09672651 0,1268804 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,09672651 0,12679016 ! sensory perception of smell GO:0007608 17 17 0,000 0,09672651 0,12670004 ! tissue remodeling GO:0048771 17 17 0,000 0,09672651 0,12661006 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,09672651 0,1265202 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,09672651 0,12643047 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,09672651 0,12634086 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,09672651 0,12625139 ! neural crest cell development GO:0014032 19 17 0,000 0,09672651 0,12616204 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,09672651 0,12607281 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,09672651 0,12598372 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,09672651 0,12589475 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,09672651 0,1258059 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,09672651 0,12571718 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,09672651 0,12562858 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,09672651 0,12554011 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,09672651 0,12545177 ! adult locomotory behavior GO:0008344 17 17 0,000 0,09672651 0,12536354 ! embryonic organ development GO:0048568 17 17 0,000 0,09672651 0,12527545 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,09672651 0,12518747 ! liver development GO:0001889 17 17 0,000 0,09672651 0,12509962 ! gene silencing GO:0016458 17 17 0,000 0,09672651 0,12501189 ! brain development GO:0007420 91 90 1,000 0,09999963 0,12915159 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,10212272 0,13180125 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,10212272 0,13170901 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,10212272 0,13161691 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,10212272 0,13152493 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,10212272 0,13143309 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,10212272 0,13134137 ! membrane docking GO:0022406 18 18 0,000 0,10212272 0,13124978 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,10212272 0,13115831 ! response to calcium ion GO:0051592 18 18 0,000 0,10212272 0,13106698 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,10212272 0,13097577 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,10212272 0,13088469 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,10212272 0,13079373 ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,10212272 0,1307029 ! ceramide metabolic process GO:0006672 18 18 0,000 0,10212272 0,1306122 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,10212272 0,13052162 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,10212272 0,13043117 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,10212272 0,13034085 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,10212272 0,13025064 ! BMP signaling pathway GO:0030509 18 18 0,000 0,10212272 0,13016057 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,10212272 0,13007062 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,10212272 0,12998079 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,10748748 0,13671458 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,10748748 0,1366203 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,10748748 0,13652614 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,10748748 0,13643211 ! feeding behavior GO:0007631 19 19 0,000 0,10748748 0,13633822 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,10748748 0,13624445 ! peroxisome organization GO:0007031 19 19 0,000 0,10748748 0,13615081 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,10748748 0,1360573 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,10748748 0,13596392 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,10748748 0,13587066 ! metanephros development GO:0001656 19 19 0,000 0,10748748 0,13577754 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,10748748 0,13568454 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,10748748 0,13559167 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,10748748 0,13549893 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,10748748 0,13540631 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,10748748 0,13531382 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,10748748 0,13522145 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,10748748 0,13512921 ! eye morphogenesis GO:0048592 19 19 0,000 0,10748748 0,1350371 ! regulation of cell shape GO:0008360 21 19 0,000 0,10748748 0,13494512 ! placenta development GO:0001890 19 19 0,000 0,10748748 0,13485325 ! response to heat GO:0009408 19 19 0,000 0,10748748 0,13476152 ! vesicle localization GO:0051648 20 19 0,000 0,10748748 0,1346699 ! epidermis development GO:0008544 94 94 1,000 0,10755435 0,13466214 ! cofactor metabolic process GO:0051186 95 94 1,000 0,10755435 0,13457072 ! regulation of muscle development GO:0048634 21 20 0,000 0,11282096 0,14106447 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,11282096 0,14096884 ! negative regulation of binding GO:0051100 21 20 0,000 0,11282096 0,14087333 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,11282096 0,14077795 ! neural tube development GO:0021915 21 20 0,000 0,11282096 0,1406827 ! phagocytosis GO:0006909 21 20 0,000 0,11282096 0,14058758 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,11282096 0,14049259 ! protein targeting to membrane GO:0006612 22 20 0,000 0,11282096 0,14039773 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,11282096 0,14030299 ! chromatin remodeling GO:0006338 20 20 0,000 0,11282096 0,14020838 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,11282096 0,1401139 ! lipid oxidation GO:0034440 20 20 0,000 0,11282096 0,14001955 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,11282096 0,13992533 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,11282096 0,13983123 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,11282096 0,13973725 ! RNA modification GO:0009451 20 20 0,000 0,11282096 0,13964341 ! single fertilization GO:0007338 21 20 0,000 0,11282096 0,13954969 ! blood circulation GO:0008015 99 98 1,000 0,11525966 0,14247053 GO:0003013|circulatory system process, ! anti-apoptosis GO:0006916 100 99 1,000 0,11720823 0,14478201 ! ectoderm development GO:0007398 99 99 1,000 0,11720823 0,14468504 ! mRNA catabolic process GO:0006402 21 21 0,000 0,11812334 0,14571708 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,11812334 0,14561962 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,11812334 0,14552228 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,11812334 0,14542507 ! Notch signaling pathway GO:0007219 22 21 0,000 0,11812334 0,14532799 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,11812334 0,14523104 ! ear morphogenesis GO:0042471 21 21 0,000 0,11812334 0,14513422 ! organic anion transport GO:0015711 21 21 0,000 0,11812334 0,14503752 ! cholesterol transport GO:0030301 21 21 0,000 0,11812334 0,14494096 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,11812334 0,14484453 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,11812334 0,14474822 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,11812334 0,14465204 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,11812334 0,14455599 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,11812334 0,14446007 ! regulation of proteolysis GO:0030162 21 21 0,000 0,11812334 0,14436427 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,11812334 0,1442686 ! RNA export from nucleus GO:0006405 22 22 0,000 0,1233948 0,15060704 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,1233948 0,15050736 ! regulation of ion transport GO:0043269 22 22 0,000 0,1233948 0,15040782 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,1233948 0,15030841 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 0,000 0,1233948 0,15020913 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,1233948 0,15010998 ! ovulation cycle process GO:0022602 22 22 0,000 0,1233948 0,15001097 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,1233948 0,14991208 ! cell chemotaxis GO:0060326 23 22 0,000 0,1233948 0,14981332 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,1233948 0,1497147 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,1233948 0,1496162 ! biopolymer methylation GO:0043414 22 22 0,000 0,1233948 0,14951783 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,1233948 0,1494196 ! detection of external stimulus GO:0009581 23 22 0,000 0,1233948 0,14932149 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,1233948 0,14922351 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,1233948 0,14912566 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,1233948 0,14902793 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,1233948 0,14893034 ! aerobic respiration GO:0009060 22 22 0,000 0,1233948 0,14883287 ! cytokine production GO:0001816 22 22 0,000 0,1233948 0,14873553 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,1233948 0,14863832 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,12863552 0,15484994 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,12863552 0,15474886 ! viral infectious cycle GO:0019058 23 23 0,000 0,12863552 0,15464792 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,12863552 0,15454711 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,12863552 0,15444642 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,12863552 0,15434587 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,12863552 0,15424545 ! endocrine system development GO:0035270 23 23 0,000 0,12863552 0,15414516 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,12863552 0,154045 ! positive regulation of growth GO:0045927 23 23 0,000 0,12863552 0,15394497 ! female gonad development GO:0008585 23 23 0,000 0,12863552 0,15384507 ! lipid homeostasis GO:0055088 23 23 0,000 0,12863552 0,1537453 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,12863552 0,15364566 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,12863552 0,15354615 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,12863552 0,15344677 ! cell projection assembly GO:0030031 25 23 0,000 0,12863552 0,15334752 ! gliogenesis GO:0042063 24 24 0,000 0,13384566 0,15945543 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,13384566 0,15935242 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,13384566 0,15924955 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,13384566 0,15914681 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,13384566 0,1590442 ! ovulation cycle GO:0042698 24 24 0,000 0,13384566 0,15894172 ! fertilization GO:0009566 25 24 0,000 0,13384566 0,15883938 ! maintenance of protein location GO:0045185 25 24 0,000 0,13384566 0,15873716 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,13384566 0,15863508 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,13384566 0,15853313 ! glucan metabolic process GO:0044042 25 24 0,000 0,13384566 0,15843131 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,1390254 0,16445688 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,1390254 0,16435139 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,1390254 0,16424604 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,1390254 0,16414082 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,1390254 0,16403574 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,1390254 0,16393079 ! excretion GO:0007588 25 25 0,000 0,1390254 0,16382597 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,1390254 0,16372129 ! gastrulation GO:0007369 25 25 0,000 0,1390254 0,16361674 ! heart morphogenesis GO:0003007 25 25 0,000 0,1390254 0,16351233 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,1390254 0,16340805 ! regulation of endocytosis GO:0030100 25 25 0,000 0,1390254 0,1633039 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,1390254 0,16319989 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,1390254 0,163096 ! positive regulation of defense response GO:0031349 26 26 0,000 0,14417492 0,16902951 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,14417492 0,16892205 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,14417492 0,16881473 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,14417492 0,16870755 ! cellular defense response GO:0006968 26 26 0,000 0,14417492 0,1686005 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,14417492 0,16849359 ! regulation of protein secretion GO:0050708 26 26 0,000 0,14417492 0,16838681 ! germ cell development GO:0007281 27 26 0,000 0,14417492 0,16828017 ! pigment metabolic process GO:0042440 26 26 0,000 0,14417492 0,16817366 ! maintenance of location in cell GO:0051651 27 26 0,000 0,14417492 0,16806729 ! chloride transport GO:0006821 27 27 0,000 0,14929439 0,17392514 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,14929439 0,17381526 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,14929439 0,17370553 ! learning or memory GO:0007611 28 27 0,000 0,14929439 0,17359594 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,14929439 0,17348648 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,14929439 0,17337717 ! mesenchymal cell development GO:0014031 29 27 0,000 0,14929439 0,17326799 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,14929439 0,17315895 ! defense response to bacterium GO:0042742 27 27 0,000 0,14929439 0,17305004 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,14929439 0,17294127 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,14929439 0,17283264 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,15438398 0,17861247 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,15438398 0,17850042 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,15438398 0,17838851 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,15438398 0,17827674 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,15438398 0,1781651 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,15438398 0,17805361 ! histone modification GO:0016570 28 28 0,000 0,15438398 0,17794226 ! developmental growth GO:0048589 28 28 0,000 0,15438398 0,17783104 ! cartilage development GO:0051216 29 28 0,000 0,15438398 0,17771997 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,15944385 0,1834301 ! viral reproductive process GO:0022415 29 29 0,000 0,15944385 0,18331567 ! leukocyte migration GO:0050900 30 29 0,000 0,15944385 0,18320138 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,15944385 0,18308724 ! antigen processing and presentation GO:0019882 29 29 0,000 0,15944385 0,18297324 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,15944385 0,18285938 ! tRNA processing GO:0008033 29 29 0,000 0,15944385 0,18274566 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,15944385 0,18263208 ! covalent chromatin modification GO:0016569 29 29 0,000 0,15944385 0,18251864 ! adult behavior GO:0030534 30 29 0,000 0,15944385 0,18240535 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,15944385 0,18229219 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,15944385 0,18217918 ! transition metal ion transport GO:0000041 31 30 0,000 0,16447418 0,18781036 ! RNA catabolic process GO:0006401 30 30 0,000 0,16447418 0,18769407 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,16447418 0,18757792 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,16447418 0,18746192 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,16447418 0,18734606 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,16447418 0,18723034 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,16447418 0,18711476 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,16447418 0,18699933 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,16447418 0,18688404 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,16447418 0,1867689 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,16447418 0,18665389 ! response to temperature stimulus GO:0009266 30 30 0,000 0,16447418 0,18653903 ! regulation of ossification GO:0030278 30 30 0,000 0,16447418 0,1864243 ! regulation of inflammatory response GO:0050727 30 30 0,000 0,16447418 0,18630972 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,16447418 0,18619528 ! vesicle organization GO:0016050 30 30 0,000 0,16447418 0,18608098 ! regulation of translational initiation GO:0006446 31 31 0,000 0,16947514 0,19162128 ! membrane fusion GO:0006944 31 31 0,000 0,16947514 0,19150379 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,16947514 0,19138645 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,16947514 0,19126925 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,16947514 0,19115219 ! ion transmembrane transport GO:0034220 31 31 0,000 0,16947514 0,19103528 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,16947514 0,19091851 ! digestion GO:0007586 31 31 0,000 0,16947514 0,19080188 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,16947514 0,1906854 ! regulation of heart contraction GO:0008016 31 31 0,000 0,16947514 0,19056906 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,16947514 0,19045286 ! camera-type eye development GO:0043010 31 31 0,000 0,16947514 0,1903368 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,16947514 0,19022088 ! cell redox homeostasis GO:0045454 32 32 0,000 0,17444689 0,19568206 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,17444689 0,19556303 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,17444689 0,19544415 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,17444689 0,19532541 ! cell maturation GO:0048469 32 32 0,000 0,17444689 0,19520681 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,17444689 0,19508836 ! nuclear export GO:0051168 32 32 0,000 0,17444689 0,19497005 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,17444689 0,19485189 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,17444689 0,19473387 ! maintenance of location GO:0051235 33 32 0,000 0,17444689 0,19461599 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,1793896 0,2000091 ! amino acid transport GO:0006865 33 33 0,000 0,1793896 0,19988817 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,1793896 0,19976739 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,1793896 0,19964676 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,1793896 0,19952627 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,1793896 0,19940593 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,18430344 0,20474456 ! response to metal ion GO:0010038 34 34 0,000 0,18430344 0,20462122 ! ear development GO:0043583 34 34 0,000 0,18430344 0,20449803 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,18430344 0,20437499 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,18430344 0,20425209 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,18430344 0,20412935 ! secondary metabolic process GO:0019748 34 34 0,000 0,18430344 0,20400675 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,18430344 0,20388429 ! viral reproduction GO:0016032 34 34 0,000 0,18430344 0,20376199 ! detection of stimulus GO:0051606 36 34 0,000 0,18430344 0,20363983 ! acute inflammatory response GO:0002526 35 35 0,000 0,18918856 0,20891223 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,18918856 0,20878713 ! mesoderm development GO:0007498 35 35 0,000 0,18918856 0,20866219 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,18918856 0,20853739 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,18918856 0,20841274 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,18918856 0,20828824 ! inorganic anion transport GO:0015698 35 35 0,000 0,18918856 0,20816389 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,18918856 0,20803969 ! regulation of immune effector process GO:0002697 35 35 0,000 0,18918856 0,20791563 ! hydrogen transport GO:0006818 36 36 0,000 0,19404514 0,21312586 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,19404514 0,21299892 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,19404514 0,21287213 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,19404514 0,2127455 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,19404514 0,21261902 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,19404514 0,21249268 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,19404514 0,2123665 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,19404514 0,21224047 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,19404514 0,21211458 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,19404514 0,21198885 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,19404514 0,21186326 ! gonad development GO:0008406 36 36 0,000 0,19404514 0,21173783 ! regulation of lipase activity GO:0060191 36 36 0,000 0,19404514 0,21161254 ! activation of immune response GO:0002253 36 36 0,000 0,19404514 0,2114874 ! coagulation GO:0050817 39 36 0,000 0,19404514 0,2113624 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,19887333 0,21649353 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! eye development GO:0001654 37 37 0,000 0,19887333 0,21636573 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,19887333 0,21623808 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,19887333 0,21611058 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,19887333 0,21598323 ! neurotransmitter transport GO:0006836 40 38 0,000 0,2036733 0,22106589 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,2036733 0,22093578 ! exocytosis GO:0006887 40 38 0,000 0,2036733 0,22080582 ! RNA elongation GO:0006354 38 38 0,000 0,2036733 0,22067601 ! regulation of neurological system process GO:0031644 38 38 0,000 0,2036733 0,22054635 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,2036733 0,22041685 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,20844521 0,22544866 ! hemostasis GO:0007599 42 39 0,000 0,20844521 0,22531643 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,20844521 0,22518436 ! response to unfolded protein GO:0006986 39 39 0,000 0,20844521 0,22505244 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,20844521 0,22492068 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,20844521 0,22478907 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,20844521 0,22465761 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,20844521 0,22452631 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,20844521 0,22439516 ! developmental maturation GO:0021700 39 39 0,000 0,20844521 0,22426417 ! limb development GO:0060173 39 39 0,000 0,20844521 0,22413332 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,21318921 0,22910071 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,21790548 0,23403251 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,21790548 0,23389621 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,21790548 0,23376007 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,21790548 0,23362408 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,21790548 0,23348825 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,22259416 0,23837364 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,22259416 0,23823521 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,22259416 0,23809694 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,22259416 0,23795883 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,22259416 0,23782089 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,22259416 0,2376831 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,22725541 0,24251981 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,22725541 0,24237947 ! humoral immune response GO:0006959 44 44 0,000 0,23188939 0,2471788 ! mRNA transport GO:0051028 44 44 0,000 0,23188939 0,24703592 ! vitamin metabolic process GO:0006766 44 44 0,000 0,23188939 0,24689321 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,23188939 0,24675066 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,23649625 0,25150756 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,23649625 0,25136251 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,23649625 0,25121763 ! protein processing GO:0016485 45 45 0,000 0,23649625 0,25107292 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,24107616 0,25578777 ! tube morphogenesis GO:0035239 47 46 0,000 0,24107616 0,2556406 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,24107616 0,2554936 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,24562926 0,26016938 ! amine transport GO:0015837 47 47 0,000 0,24562926 0,26001994 ! rhythmic process GO:0048511 47 47 0,000 0,24562926 0,25987068 ! calcium ion transport GO:0006816 48 48 0,000 0,2501557 0,26450772 ! ossification GO:0001503 50 49 0,000 0,25465565 0,26911144 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,25465565 0,26895723 ! divalent metal ion transport GO:0070838 49 49 0,000 0,25465565 0,26880318 ! response to nutrient GO:0007584 49 49 0,000 0,25465565 0,26864932 ! response to bacterium GO:0009617 50 49 0,000 0,25465565 0,26849563 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,25465565 0,26834211 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,25465565 0,26818878 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,25912924 0,27274426 ! chromatin assembly GO:0031497 50 50 0,000 0,25912924 0,27258858 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,25912924 0,27243308 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,25912924 0,27227776 ! transcription initiation GO:0006352 50 50 0,000 0,25912924 0,27212262 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,25912924 0,27196765 ! positive regulation of immune response GO:0050778 51 51 0,000 0,26357664 0,27647794 ! rRNA metabolic process GO:0016072 51 51 0,000 0,26357664 0,27632067 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,26357664 0,27616358 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,26357664 0,27600667 ! protein maturation GO:0051604 51 51 0,000 0,26357664 0,27584994 ! RNA localization GO:0006403 52 52 0,000 0,26799798 0,28031798 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,26799798 0,28015898 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,26799798 0,28000016 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,26799798 0,27984152 ! sodium ion transport GO:0006814 53 53 0,000 0,27239342 0,28427015 ! tRNA metabolic process GO:0006399 53 53 0,000 0,27239342 0,28410927 ! response to hypoxia GO:0001666 53 53 0,000 0,27239342 0,28394857 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,27239342 0,28378806 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,27239342 0,28362773 ! response to oxygen levels GO:0070482 55 54 0,000 0,27676311 0,28801491 ! response to virus GO:0009615 54 54 0,000 0,27676311 0,28785238 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,27676311 0,28769002 ! nucleosome organization GO:0034728 55 55 0,000 0,28110719 0,2920409 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,28110719 0,29187637 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,28542582 0,29619357 ! ATP metabolic process GO:0046034 57 57 0,000 0,28971913 0,30047966 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,28971913 0,30031066 ! innate immune response GO:0045087 58 58 0,000 0,29398727 0,30456354 ! carboxylic acid transport GO:0046942 59 59 0,000 0,29823038 0,30878573 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,29823038 0,30861235 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,29823038 0,30843916 ! potassium ion transport GO:0006813 60 60 0,000 0,30244861 0,31262636 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,30244861 0,31245112 ! cellular respiration GO:0045333 62 61 0,000 0,3066421 0,31660582 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,3066421 0,31642855 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,3066421 0,31625148 ! lipid transport GO:0006869 62 62 0,000 0,31081099 0,32037174 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,31081099 0,32019266 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,31081099 0,32001378 GO:0060429|epithelium development, ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,31081099 0,3198351 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,31495543 0,323919 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,31495543 0,32373835 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,31907554 0,32779054 ! anion transport GO:0006820 65 65 0,000 0,32317148 0,33181339 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,32724338 0,33580709 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,32724338 0,33562022 ! DNA packaging GO:0006323 66 66 0,000 0,32724338 0,33543356 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,32724338 0,3352471 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,33129137 0,33920555 ! muscle contraction GO:0006936 67 67 0,000 0,33129137 0,33901721 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,33129137 0,33882907 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,33531559 0,34275465 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,33531559 0,34256466 ! regulation of translation GO:0006417 69 69 0,000 0,33931619 0,34645969 ! regionalization GO:0003002 70 69 0,000 0,33931619 0,34626785 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,34329329 0,35013256 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,34724703 0,35396918 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,34724703 0,35377351 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,34724703 0,35357806 ! secretion by cell GO:0032940 75 72 0,000 0,35117755 0,35738278 ! muscle system process GO:0003012 72 72 0,000 0,35117755 0,35718555 ! sensory organ development GO:0007423 72 72 0,000 0,35117755 0,35698854 ! regulation of cytokine production GO:0001817 72 72 0,000 0,35117755 0,35679174 ! electron transport chain GO:0022900 75 74 0,000 0,35896943 0,36450725 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,36283106 0,36822557 ! response to oxidative stress GO:0006979 76 75 0,000 0,36283106 0,36802292 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,36283106 0,36782048 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,36666999 0,37150786 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,37048635 0,37516832 ! metal ion homeostasis GO:0055065 78 78 0,000 0,37428027 0,37880206 ! regulation of immune response GO:0050776 78 78 0,000 0,37428027 0,37859415 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,38180132 0,38599003 ! lipid catabolic process GO:0016042 82 81 0,000 0,38552869 0,38954461 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,39291778 0,39679313 ! ncRNA processing GO:0034470 83 83 0,000 0,39291778 0,39657583 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,40022015 0,40372509 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,4110133 0,41438594 ! chemotaxis GO:0006935 90 89 0,000 0,41456872 0,41774202 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,41456872 0,41751375 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,41810321 0,42084337 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,42161687 0,42414841 ! visual perception GO:0007601 93 92 0,000 0,42510983 0,42742903 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,42510983 0,42719597 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,42510983 0,42696317 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,42510983 0,42673062 ! tissue morphogenesis GO:0048729 94 93 0,000 0,42858221 0,42998204 ! regulation of response to stress GO:0080134 97 94 0,000 0,43203412 0,4332094 ! pattern specification process GO:0007389 96 94 0,000 0,43203412 0,43297384 ! endocytosis GO:0006897 99 98 0,000 0,44563946 0,44636605 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,44563946 0,44612359 ! regulation of system process GO:0044057 98 98 0,000 0,44563946 0,4458814 ! response to other organism GO:0051707 101 100 0,000 0,45232237 0,45232237