pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6614-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 6 6 4,000 2,411E-11 5,546E-08 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 4,000 9,957E-10 1,145E-06 ! cell cycle checkpoint GO:0000075 108 64 7,000 1,784E-09 1,368E-06 ! negative regulation of peptide secretion GO:0002792 6 5 3,000 3,903E-09 2,244E-06 GO:0046676|negative regulation of insulin secretion, ! DNA damage checkpoint GO:0000077 53 31 5,000 1,358E-08 6,248E-06 ! DNA damage response, signal transduction GO:0042770 96 56 6,000 1,938E-08 7,43E-06 ! DNA integrity checkpoint GO:0031570 57 34 5,000 2,449E-08 8,047E-06 ! organ growth GO:0035265 11 7 3,000 2,71E-08 7,79E-06 ! regulation of growth hormone secretion GO:0060123 11 7 3,000 2,71E-08 6,925E-06 ! apoptotic mitochondrial changes GO:0008637 29 18 4,000 3,272E-08 7,526E-06 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 3,000 5,397E-08 1,128E-05 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 3,000 1,606E-07 3,078E-05 GO:0010812|negative regulation of cell-substrate adhesion, ! oxygen transport GO:0015671 15 11 3,000 2,513E-07 4,446E-05 ! negative regulation of mast cell proliferation GO:0070667 17 11 3,000 2,513E-07 4,129E-05 GO:0042130|negative regulation of T cell proliferation, ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 3,047E-07 4,673E-05 ! cell cycle arrest GO:0007050 150 86 6,000 3,94E-07 5,664E-05 ! gas transport GO:0015669 18 13 3,000 5,4E-07 7,306E-05 ! regulation of protein stability GO:0031647 48 32 4,000 7,247E-07 9,26E-05 ! inositol metabolic process GO:0006020 20 14 3,000 7,529E-07 9,114E-05 ! release of cytochrome c from mitochondria GO:0001836 23 14 3,000 7,529E-07 8,658E-05 ! negative regulation of hormone secretion GO:0046888 20 15 3,000 1,022E-06 1,12E-04 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 3,000 1,022E-06 1,069E-04 ! negative regulation of leukocyte proliferation GO:0070664 25 15 3,000 1,022E-06 1,022E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of intracellular protein transport GO:0033157 59 35 4,000 1,154E-06 1,105E-04 ! endothelial cell migration GO:0043542 22 16 3,000 1,358E-06 1,249E-04 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 2,000 1,494E-06 1,321E-04 ! positive regulation of hormone secretion GO:0046887 24 17 3,000 1,768E-06 1,506E-04 ! negative regulation of T cell activation GO:0050868 25 18 3,000 2,264E-06 1,86E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 2,289E-06 1,815E-04 ! cell structure disassembly during apoptosis GO:0006921 24 19 3,000 2,856E-06 2,19E-04 ! apoptotic nuclear changes GO:0030262 24 19 3,000 2,856E-06 2,119E-04 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 4,000 2,934E-06 2,109E-04 ! regulation of helicase activity GO:0051095 11 6 2,000 2,976E-06 2,074E-04 ! negative regulation of focal adhesion formation GO:0051895 16 6 2,000 2,976E-06 2,013E-04 ! negative regulation of B cell activation GO:0050869 9 6 2,000 2,976E-06 1,956E-04 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 3,000 4,374E-06 2,794E-04 ! regulation of insulin secretion GO:0050796 26 21 3,000 4,374E-06 2,719E-04 ! regulation of focal adhesion formation GO:0051893 17 7 2,000 5,188E-06 3,14E-04 ! regulation of cell-matrix adhesion GO:0001952 51 22 3,000 5,324E-06 3,14E-04 GO:0010810|regulation of cell-substrate adhesion, ! regulation of intracellular transport GO:0032386 78 49 4,000 6,385E-06 3,671E-04 ! regulation of DNA metabolic process GO:0051052 135 85 5,000 6,391E-06 3,585E-04 ! positive regulation of MAP kinase activity GO:0043406 121 85 5,000 6,391E-06 3,5E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 8,268E-06 4,422E-04 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 8,268E-06 4,322E-04 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 2,000 8,268E-06 4,226E-04 ! regulation of peptide secretion GO:0002791 34 25 3,000 9,093E-06 4,547E-04 ! negative regulation of lymphocyte activation GO:0051250 37 25 3,000 9,093E-06 4,45E-04 ! negative regulation of leukocyte activation GO:0002695 39 27 3,000 1,251E-05 5,995E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 4,000 1,355E-05 6,362E-04 ! triglyceride metabolic process GO:0006641 34 28 3,000 1,454E-05 6,687E-04 ! negative regulation of kinase activity GO:0033673 100 58 4,000 1,477E-05 6,66E-04 ! regulation of B cell proliferation GO:0030888 15 10 2,000 1,758E-05 7,775E-04 ! meiosis GO:0007126 96 61 4,000 1,893E-05 8,216E-04 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of transferase activity GO:0051348 105 61 4,000 1,893E-05 8,064E-04 ! negative regulation of cell activation GO:0050866 44 30 3,000 1,93E-05 8,07E-04 ! meiotic cell cycle GO:0051321 97 62 4,000 2,051E-05 8,422E-04 ! negative regulation of secretion GO:0051048 49 31 3,000 2,207E-05 8,904E-04 ! meiosis I GO:0007127 52 32 3,000 2,511E-05 9,959E-04 ! neutral lipid metabolic process GO:0006638 41 32 3,000 2,511E-05 9,791E-04 GO:0006639|acylglycerol metabolic process, ! negative regulation of cell adhesion GO:0007162 67 33 3,000 2,846E-05 1,091E-03 ! carbohydrate homeostasis GO:0033500 39 33 3,000 2,846E-05 1,073E-03 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 3,000 2,846E-05 1,056E-03 ! glycerol ether metabolic process GO:0006662 44 34 3,000 3,212E-05 1,173E-03 ! polyol metabolic process GO:0019751 44 34 3,000 3,212E-05 1,154E-03 ! regulation of hormone secretion GO:0046883 48 36 3,000 4,047E-05 1,432E-03 ! organic ether metabolic process GO:0018904 46 36 3,000 4,047E-05 1,41E-03 ! hormone-mediated signaling GO:0009755 49 36 3,000 4,047E-05 1,389E-03 ! negative regulation of transport GO:0051051 116 73 4,000 4,543E-05 1,537E-03 ! mitochondrion organization GO:0007005 104 73 4,000 4,543E-05 1,514E-03 ! cellular response to hormone stimulus GO:0032870 109 74 4,000 4,852E-05 1,594E-03 ! regulation of T cell proliferation GO:0042129 58 38 3,000 5,03E-05 1,629E-03 ! regulation of protein transport GO:0051223 114 76 4,000 5,518E-05 1,763E-03 GO:0070201|regulation of establishment of protein localization, ! cardiac muscle tissue development GO:0048738 23 15 2,000 6,537E-05 2,059E-03 ! cellular component disassembly GO:0022411 64 42 3,000 7,503E-05 2,332E-03 ! activation of caspase activity GO:0006919 65 43 3,000 8,238E-05 2,526E-03 ! regulation of cell adhesion GO:0030155 159 83 4,000 8,419E-05 2,548E-03 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 9,025E-05 2,696E-03 ! regulation of protein localization GO:0032880 132 85 4,000 9,431E-05 2,781E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 9,865E-05 2,872E-03 ! response to UV GO:0009411 75 46 3,000 1,076E-04 3,093E-03 ! negative regulation of immune system process GO:0002683 73 47 3,000 1,171E-04 3,326E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 1,171E-04 3,285E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of caspase activity GO:0043280 72 48 3,000 1,273E-04 3,526E-03 GO:0010952|positive regulation of peptidase activity, ! regulation of multicellular organism growth GO:0040014 65 50 3,000 1,494E-04 4,09E-03 ! positive regulation of secretion GO:0051047 71 51 3,000 1,614E-04 4,368E-03 ! aging GO:0007568 79 52 3,000 1,742E-04 4,658E-03 ! regulation of DNA recombination GO:0000018 40 21 2,000 1,866E-04 4,934E-03 ! DNA catabolic process GO:0006308 67 54 3,000 2,018E-04 5,274E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 2,153E-04 5,563E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 2,466E-04 6,302E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 2,466E-04 6,233E-03 ! multicellular organism reproduction GO:0032504 83 57 3,000 2,49E-04 6,224E-03 GO:0048609|reproductive process in a multicellular organism, ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 2,831E-04 7E-03 ! epithelial cell proliferation GO:0050673 6 5 1,000 2,831E-04 6,926E-03 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 2,831E-04 6,853E-03 ! induction of apoptosis by oxidative stress GO:0008631 5 5 1,000 2,831E-04 6,782E-03 ! centrosome duplication GO:0051298 5 5 1,000 2,831E-04 6,712E-03 ! determination of adult lifespan GO:0008340 8 5 1,000 2,831E-04 6,643E-03 ! activation of MAPK activity GO:0000187 84 59 3,000 2,845E-04 6,61E-03 ! regulation of chromosome organization GO:0033044 35 25 2,000 3,178E-04 7,309E-03 ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 3,178E-04 7,237E-03 ! urogenital system development GO:0001655 101 61 3,000 3,236E-04 7,296E-03 ! negative regulation of cell growth GO:0030308 106 62 3,000 3,445E-04 7,692E-03 ! negative regulation of protein kinase cascade GO:0010741 51 26 2,000 3,578E-04 7,914E-03 ! negative regulation of cell size GO:0045792 108 64 3,000 3,891E-04 8,524E-03 ! regulation of caspase activity GO:0043281 97 65 3,000 4,13E-04 8,96E-03 ! prostate gland development GO:0030850 9 6 1,000 4,231E-04 9,095E-03 ! activation of MAPKKK activity GO:0000185 10 6 1,000 4,231E-04 9,01E-03 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 4,231E-04 8,928E-03 ! ER overload response GO:0006983 7 6 1,000 4,231E-04 8,847E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 4,231E-04 8,767E-03 ! neuron apoptosis GO:0051402 8 6 1,000 4,231E-04 8,689E-03 ! negative regulation of DNA recombination GO:0045910 9 6 1,000 4,231E-04 8,612E-03 ! anterograde axon cargo transport GO:0008089 8 6 1,000 4,231E-04 8,536E-03 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 4,231E-04 8,462E-03 ! dendrite morphogenesis GO:0048813 9 6 1,000 4,231E-04 8,389E-03 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 4,231E-04 8,317E-03 ! regulation of B cell activation GO:0050864 42 28 2,000 4,474E-04 8,72E-03 ! regulation of endopeptidase activity GO:0052548 99 67 3,000 4,637E-04 8,962E-03 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 1,000 5,903E-04 0,01131339 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of lipid kinase activity GO:0043550 12 7 1,000 5,903E-04 0,01121989 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 5,903E-04 0,01112793 ! central nervous system neuron axonogenesis GO:0021955 14 7 1,000 5,903E-04 0,01103745 GO:0021952|central nervous system projection neuron axonogenesis, ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 5,903E-04 0,01094844 ! B cell lineage commitment GO:0002326 17 7 1,000 5,903E-04 0,01086085 ! multicellular organismal aging GO:0010259 11 7 1,000 5,903E-04 0,01077466 ! T cell lineage commitment GO:0002360 12 7 1,000 5,903E-04 0,01068982 ! response to tumor cell GO:0002347 12 7 1,000 5,903E-04 0,0106063 ! regulation of peptidase activity GO:0052547 106 72 3,000 6,098E-04 0,01087201 ! negative regulation of DNA metabolic process GO:0051053 48 32 2,000 6,669E-04 0,01179893 ! negative regulation of growth GO:0045926 123 75 3,000 7,116E-04 0,01249422 ! axon extension GO:0048675 11 8 1,000 7,843E-04 0,01366518 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 7,843E-04 0,01356243 ! middle ear morphogenesis GO:0042474 9 8 1,000 7,843E-04 0,01346122 ! polyamine biosynthetic process GO:0006596 9 8 1,000 7,843E-04 0,01336151 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 7,843E-04 0,01326326 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 7,843E-04 0,01316645 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 7,843E-04 0,01307104 ! regulation of telomere maintenance GO:0032204 10 8 1,000 7,843E-04 0,01297701 ! sex differentiation GO:0007548 105 77 3,000 7,859E-04 0,0129107 ! development of primary male sexual characteristics GO:0046546 44 34 2,000 7,983E-04 0,01302269 ! regulation of cell cycle process GO:0010564 122 81 3,000 9,505E-04 0,01539531 ! regulation of activated T cell proliferation GO:0046006 15 9 1,000 1,005E-03 0,01616125 ! motor axon guidance GO:0008045 14 9 1,000 1,005E-03 0,01604902 ! pigmentation GO:0043473 74 38 2,000 1,108E-03 0,01757718 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 1,189E-03 0,01872544 ! male sex differentiation GO:0046661 53 39 2,000 1,196E-03 0,0187101 ! pathogenesis GO:0009405 13 10 1,000 1,252E-03 0,01945078 ! polyamine metabolic process GO:0006595 14 10 1,000 1,252E-03 0,01932023 ! response to X-ray GO:0010165 16 10 1,000 1,252E-03 0,01919143 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 1,252E-03 0,01906434 ! interphase GO:0051325 159 88 3,000 1,295E-03 0,01959023 ! reproductive developmental process GO:0003006 127 89 3,000 1,35E-03 0,02029505 ! regulation of T cell activation GO:0050863 128 89 3,000 1,35E-03 0,02016326 ! regulation of T cell differentiation GO:0045580 59 41 2,000 1,384E-03 0,02053759 ! hormone metabolic process GO:0042445 121 90 3,000 1,407E-03 0,02074572 ! detection of mechanical stimulus GO:0050982 15 11 1,000 1,524E-03 0,022332 ! T cell proliferation GO:0042098 20 11 1,000 1,524E-03 0,02219065 ! regulation of mRNA processing GO:0050684 18 11 1,000 1,524E-03 0,02205109 ! focal adhesion formation GO:0048041 24 11 1,000 1,524E-03 0,02191327 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,524E-03 0,02177716 ! T cell homeostasis GO:0043029 20 11 1,000 1,524E-03 0,02164274 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 1,000 1,524E-03 0,02150996 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! male genitalia development GO:0030539 13 11 1,000 1,524E-03 0,0213788 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,59E-03 0,02216262 ! glycolysis GO:0006096 53 44 2,000 1,7E-03 0,0235495 ! negative regulation of cell migration GO:0030336 92 44 2,000 1,7E-03 0,02340848 ! response to light stimulus GO:0009416 153 96 3,000 1,785E-03 0,02443912 ! immunoglobulin production during immune response GO:0002381 20 12 1,000 1,823E-03 0,02480851 ! response to gamma radiation GO:0010332 20 12 1,000 1,823E-03 0,02466258 ! induction of apoptosis via death domain receptors GO:0008625 15 13 1,000 2,147E-03 0,02887497 ! genitalia development GO:0048806 15 13 1,000 2,147E-03 0,02870709 ! regulation of cellular pH GO:0030641 20 13 1,000 2,147E-03 0,02854116 ! lymphocyte homeostasis GO:0002260 24 13 1,000 2,147E-03 0,02837713 ! regulation of DNA replication GO:0006275 75 48 2,000 2,186E-03 0,02872407 ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 2,186E-03 0,02856086 ! lipid modification GO:0030258 73 50 2,000 2,458E-03 0,03193429 ! cellular response to starvation GO:0009267 21 14 1,000 2,496E-03 0,03224962 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 2,496E-03 0,03206946 ! axon cargo transport GO:0008088 27 14 1,000 2,496E-03 0,03189129 ! activation of MAPKK activity GO:0000186 21 14 1,000 2,496E-03 0,0317151 ! G1/S transition checkpoint GO:0031575 33 14 1,000 2,496E-03 0,03154084 ! positive regulation of cell migration GO:0030335 92 51 2,000 2,601E-03 0,03269091 ! regulation of protein catabolic process GO:0042176 77 51 2,000 2,601E-03 0,03251325 ! negative regulation of cell motion GO:0051271 104 51 2,000 2,601E-03 0,0323375 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 2,87E-03 0,03548627 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 2,87E-03 0,03529651 ! centrosome cycle GO:0007098 16 15 1,000 2,87E-03 0,03510876 ! regulation of survival gene product expression GO:0045884 20 15 1,000 2,87E-03 0,034923 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 2,87E-03 0,0347392 ! kidney development GO:0001822 90 53 2,000 2,903E-03 0,03496201 ! regulation of mitosis GO:0007088 84 54 2,000 3,062E-03 0,0366836 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 2,000 3,062E-03 0,03649353 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 1,000 3,268E-03 0,03874762 ! G1 phase GO:0051318 27 16 1,000 3,268E-03 0,03854891 ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 1,000 3,268E-03 0,03835223 ! positive regulation of cell motion GO:0051272 99 56 2,000 3,396E-03 0,03964782 ! cell-substrate junction assembly GO:0007044 39 17 1,000 3,691E-03 0,04287669 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 3,691E-03 0,04266123 ! actin filament bundle formation GO:0051017 26 17 1,000 3,691E-03 0,04244792 ! neuromuscular junction development GO:0007528 23 17 1,000 3,691E-03 0,04223674 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 3,691E-03 0,04202765 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 3,691E-03 0,04182061 ! phosphoinositide metabolic process GO:0030384 87 60 2,000 4,128E-03 0,04654024 ! positive regulation of DNA replication GO:0045740 29 18 1,000 4,138E-03 0,04642669 ! pigmentation during development GO:0048066 31 18 1,000 4,138E-03 0,04620132 ! central nervous system neuron development GO:0021954 30 18 1,000 4,138E-03 0,04597813 ! cellular response to nutrient levels GO:0031669 27 18 1,000 4,138E-03 0,04575708 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 4,138E-03 0,04553814 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 4,138E-03 0,0453213 ! homeostasis of number of cells GO:0048872 84 61 2,000 4,325E-03 0,04714122 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 4,609E-03 0,05000043 ! response to alkaloid GO:0043279 32 19 1,000 4,609E-03 0,04976568 ! sex determination GO:0007530 29 19 1,000 4,609E-03 0,04953313 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 4,609E-03 0,04930274 ! somatic diversification of immunoglobulins GO:0016445 29 19 1,000 4,609E-03 0,04907449 ! protein stabilization GO:0050821 26 19 1,000 4,609E-03 0,04884834 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 4,609E-03 0,04862427 ! reciprocal meiotic recombination GO:0007131 31 19 1,000 4,609E-03 0,04840224 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 4,609E-03 0,04818223 ! response to starvation GO:0042594 30 19 1,000 4,609E-03 0,04796421 ! regulation of transcription factor activity GO:0051090 97 63 2,000 4,735E-03 0,04905752 GO:0090046|regulation of transcription regulator activity, ! hexose catabolic process GO:0019320 82 64 2,000 4,949E-03 0,05104199 ! microtubule-based transport GO:0010970 37 20 1,000 5,103E-03 0,05239658 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 5,103E-03 0,0521637 ! central nervous system neuron differentiation GO:0021953 33 20 1,000 5,103E-03 0,05193289 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 5,103E-03 0,05170411 ! reproductive structure development GO:0048608 90 65 2,000 5,168E-03 0,05213669 ! B cell activation GO:0042113 104 65 2,000 5,168E-03 0,05190902 ! axon guidance GO:0007411 99 66 2,000 5,394E-03 0,05393597 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 1,000 5,62E-03 0,05596148 GO:0016444|somatic cell DNA recombination, ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 5,62E-03 0,05572026 ! dendrite development GO:0016358 35 21 1,000 5,62E-03 0,05548112 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 5,62E-03 0,05524402 ! cell aging GO:0007569 32 21 1,000 5,62E-03 0,05500894 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 5,62E-03 0,05477585 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,62E-03 0,05454473 ! immunoglobulin production GO:0002377 33 21 1,000 5,62E-03 0,05431555 GO:0002440|production of molecular mediator of immune response, ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,62E-03 0,05408829 ! development of primary sexual characteristics GO:0045137 92 68 2,000 5,862E-03 0,05617406 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 6,161E-03 0,05879791 ! regulation of anti-apoptosis GO:0045767 36 22 1,000 6,161E-03 0,05855495 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 6,161E-03 0,05831398 ! vasculogenesis GO:0001570 33 22 1,000 6,161E-03 0,05807499 ! microtubule organizing center organization GO:0031023 28 22 1,000 6,161E-03 0,05783795 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 6,161E-03 0,05760283 ! leukocyte homeostasis GO:0001776 33 22 1,000 6,161E-03 0,05736962 ! protein tetramerization GO:0051262 39 22 1,000 6,161E-03 0,05713829 ! regulation of catabolic process GO:0009894 106 70 2,000 6,353E-03 0,05868512 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 6,608E-03 0,06079437 ! monosaccharide catabolic process GO:0046365 91 71 2,000 6,608E-03 0,06055216 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 6,724E-03 0,06137234 ! myelination GO:0042552 35 23 1,000 6,724E-03 0,06112976 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 6,724E-03 0,0608891 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 6,724E-03 0,06065031 ! negative regulation of DNA replication GO:0008156 35 23 1,000 6,724E-03 0,0604134 ! lymphocyte proliferation GO:0046651 36 23 1,000 6,724E-03 0,06017833 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 6,724E-03 0,05994508 ! somatic diversification of immune receptors GO:0002200 35 23 1,000 6,724E-03 0,05971363 ! negative regulation of catabolic process GO:0009895 34 23 1,000 6,724E-03 0,05948396 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 7,31E-03 0,06441806 ! mitochondrial membrane organization GO:0007006 39 24 1,000 7,31E-03 0,06417219 ! negative regulation of cell development GO:0010721 56 24 1,000 7,31E-03 0,06392819 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 7,31E-03 0,06368604 ! glutathione metabolic process GO:0006749 29 24 1,000 7,31E-03 0,06344571 ! protein import into nucleus GO:0006606 118 74 2,000 7,409E-03 0,06405977 ! regulation of ligase activity GO:0051340 114 75 2,000 7,688E-03 0,06622359 ! nuclear import GO:0051170 121 75 2,000 7,688E-03 0,06597648 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 7,918E-03 0,06770099 GO:0045936|negative regulation of phosphate metabolic process, ! male gonad development GO:0008584 33 25 1,000 7,918E-03 0,06745025 ! iron ion homeostasis GO:0055072 39 25 1,000 7,918E-03 0,06720136 ! positive regulation of nuclear division GO:0051785 39 25 1,000 7,918E-03 0,06695429 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 1,000 7,918E-03 0,06670904 GO:0032943|mononuclear cell proliferation, ! regulation of DNA binding GO:0051101 119 77 2,000 8,264E-03 0,06937143 ! gland development GO:0048732 148 77 2,000 8,264E-03 0,06911917 ! regulation of pH GO:0006885 36 26 1,000 8,548E-03 0,0712341 ! T cell activation GO:0042110 134 79 2,000 8,866E-03 0,0736135 ! alcohol catabolic process GO:0046164 104 80 2,000 9,176E-03 0,075914 ! protein localization in nucleus GO:0034504 133 80 2,000 9,176E-03 0,07564191 ! response to ionizing radiation GO:0010212 47 27 1,000 9,2E-03 0,07557027 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 9,2E-03 0,07530134 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 1,000 9,2E-03 0,07503431 ! cell junction assembly GO:0034329 56 28 1,000 9,873E-03 0,08024096 ! erythrocyte differentiation GO:0030218 38 28 1,000 9,873E-03 0,07995842 ! ensheathment of neurons GO:0007272 43 28 1,000 9,873E-03 0,07967787 GO:0008366|axon ensheathment, ! positive regulation of catabolic process GO:0009896 40 28 1,000 9,873E-03 0,07939927 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,01047908 0,08397869 ! mismatch repair GO:0006298 34 29 1,000 0,01056765 0,08439443 ! tissue homeostasis GO:0001894 42 29 1,000 0,01056765 0,0841024 GO:0048871|multicellular organismal homeostasis, ! rRNA metabolic process GO:0016072 107 85 2,000 0,01082083 0,08582034 GO:0006364|rRNA processing, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 1,000 0,01128319 0,08917982 ! spindle organization GO:0007051 37 30 1,000 0,01128319 0,08887441 ! mammary gland development GO:0030879 57 31 1,000 0,01201949 0,09435097 ! odontogenesis GO:0042476 50 31 1,000 0,01201949 0,09403005 ! metanephros development GO:0001656 58 31 1,000 0,01201949 0,0937113 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01201949 0,09339471 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,01201949 0,09308025 ! biogenic amine biosynthetic process GO:0042401 44 31 1,000 0,01201949 0,0927679 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,01277633 0,09827948 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01277633 0,09795189 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01277633 0,09762646 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,01277633 0,0973032 ! glycerophospholipid metabolic process GO:0006650 130 92 2,000 0,01339346 0,1016665 ! cell fate commitment GO:0045165 141 92 2,000 0,01339346 0,10133207 ! DNA recombination GO:0006310 146 92 2,000 0,01339346 0,10099984 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,01355347 0,10187247 ! sister chromatid segregation GO:0000819 46 33 1,000 0,01355347 0,10154064 ! ear morphogenesis GO:0042471 42 33 1,000 0,01355347 0,10121096 ! cell junction organization GO:0034330 63 33 1,000 0,01355347 0,10088342 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,01355347 0,10055799 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,01355347 0,10023465 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,01355347 0,09991339 ! cytokinesis GO:0000910 52 33 1,000 0,01355347 0,09959417 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 0,01378696 0,1009873 ! carbohydrate catabolic process GO:0016052 121 93 2,000 0,01378696 0,10066671 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,01435066 0,10445103 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,01435066 0,10412153 ! neuron migration GO:0001764 46 34 1,000 0,01435066 0,1037941 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,01435066 0,10346873 ! regulation of binding GO:0051098 151 95 2,000 0,01459362 0,10489163 ! angiogenesis GO:0001525 149 95 2,000 0,01459362 0,10456487 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 0,0150068 0,1071914 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,01516768 0,10800518 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,01516768 0,10767183 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,0160043 0,11326121 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 0,0160043 0,11291378 ! extracellular structure organization GO:0043062 156 99 2,000 0,01628587 0,11454891 ! protein import GO:0017038 156 99 2,000 0,01628587 0,11419968 ! protein localization in organelle GO:0033365 161 100 2,000 0,01672544 0,11692555 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,0177354 0,12361039 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,01862943 0,12944924 ! cell growth GO:0016049 61 39 1,000 0,01862943 0,12905934 ! synapse organization GO:0050808 55 39 1,000 0,01862943 0,12867177 ! regulation of tube size GO:0035150 60 40 1,000 0,01954215 0,13457172 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,01954215 0,13417001 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 0,01954215 0,1337707 ! peptide metabolic process GO:0006518 56 40 1,000 0,01954215 0,13337375 ! T cell differentiation GO:0030217 65 40 1,000 0,01954215 0,13297915 ! double-strand break repair GO:0006302 67 40 1,000 0,01954215 0,13258689 ! B cell differentiation GO:0030183 62 40 1,000 0,01954215 0,13219692 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,01954215 0,13180925 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,01954215 0,13142384 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,02047334 0,13728478 ! glucose transport GO:0015758 52 41 1,000 0,02047334 0,13688569 ! endosome transport GO:0016197 71 41 1,000 0,02047334 0,13648892 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,02047334 0,13609445 ! mitochondrial transport GO:0006839 60 42 1,000 0,02142277 0,14199529 ! hexose transport GO:0008645 54 42 1,000 0,02142277 0,14158726 GO:0015749|monosaccharide transport, ! positive regulation of binding GO:0051099 59 43 1,000 0,02239022 0,14755735 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,02239022 0,14713576 ! response to insulin stimulus GO:0032868 63 43 1,000 0,02239022 0,14671657 ! regulation of action potential GO:0001508 71 44 1,000 0,02337549 0,15273757 ! induction of apoptosis by extracellular signals GO:0008624 74 44 1,000 0,02337549 0,15230488 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,02337549 0,15187464 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,02437835 0,15794423 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,02437835 0,15750056 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,026436 0,17031595 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02660024 0,1708954 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02660024 0,17041936 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02660024 0,16994598 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02660024 0,16947521 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02660024 0,16900705 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02660024 0,16854146 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02660024 0,16807844 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02660024 0,16761795 ! sleep GO:0030431 11 5 0,000 0,02660024 0,16715998 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02660024 0,1667045 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02660024 0,1662515 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02660024 0,16580095 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02660024 0,16535284 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02660024 0,16490715 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02660024 0,16446385 ! tongue development GO:0043586 6 5 0,000 0,02660024 0,16402293 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02660024 0,16358436 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02660024 0,16314814 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02660024 0,16271423 ! cobalt ion transport GO:0006824 9 5 0,000 0,02660024 0,16228263 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02660024 0,16185331 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02660024 0,16142626 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02660024 0,16100145 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02660024 0,16057888 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02660024 0,16015851 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02660024 0,15974034 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02660024 0,15932435 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02660024 0,15891052 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02660024 0,15849884 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02660024 0,15808928 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02660024 0,15768183 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02660024 0,15727648 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02660024 0,15687321 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02660024 0,156472 ! malate metabolic process GO:0006108 7 5 0,000 0,02660024 0,15607284 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02660024 0,1556757 ! behavioral response to pain GO:0048266 7 5 0,000 0,02660024 0,15528059 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02660024 0,15488747 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02660024 0,15449634 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02660024 0,15410718 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02660024 0,15371998 ! mating behavior GO:0007617 6 5 0,000 0,02660024 0,15333472 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02660024 0,15295138 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02660024 0,15256995 ! rhythmic behavior GO:0007622 12 5 0,000 0,02660024 0,15219043 ! copulation GO:0007620 7 5 0,000 0,02660024 0,15181278 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02660024 0,15143701 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02660024 0,15106309 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02660024 0,15069101 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02660024 0,15032077 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02660024 0,14995233 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02660024 0,1495857 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02660024 0,14922086 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02660024 0,14885779 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02660024 0,14849648 ! response to protozoan GO:0001562 9 5 0,000 0,02660024 0,14813693 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02660024 0,14777911 ! lymph vessel development GO:0001945 7 5 0,000 0,02660024 0,14742302 ! endochondral ossification GO:0001958 12 5 0,000 0,02660024 0,14706863 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02660024 0,14671595 ! parathyroid gland development GO:0060017 8 5 0,000 0,02660024 0,14636496 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02660024 0,14601564 ! anagen GO:0042640 6 5 0,000 0,02660024 0,14566798 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02660024 0,14532198 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02660024 0,14497761 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02660024 0,14463487 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02660024 0,14429375 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02660024 0,14395424 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02660024 0,14361632 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02660024 0,14327998 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02660024 0,14294521 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02660024 0,14261201 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02660024 0,14228035 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02660024 0,14195024 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02660024 0,14162165 ! ovulation GO:0030728 6 5 0,000 0,02660024 0,14129458 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02660024 0,14096901 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02660024 0,14064495 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02660024 0,14032237 ! response to pH GO:0009268 9 5 0,000 0,02660024 0,14000126 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02660024 0,13968163 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02660024 0,13936344 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02660024 0,13904671 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02660024 0,13873141 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02660024 0,13841754 ! polyol catabolic process GO:0046174 7 5 0,000 0,02660024 0,13810508 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02660024 0,13779404 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02660024 0,13748439 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02660024 0,13717613 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02660024 0,13686924 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02660024 0,13656373 ! urea metabolic process GO:0019627 6 5 0,000 0,02660024 0,13625958 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02660024 0,13595678 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02660024 0,13565533 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02660024 0,1353552 ! neutrophil activation GO:0042119 5 5 0,000 0,02660024 0,13505641 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02660024 0,13475892 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02660024 0,13446275 ! response to food GO:0032094 5 5 0,000 0,02660024 0,13416788 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02660024 0,13387429 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02660024 0,13358199 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02660024 0,13329096 ! forebrain neuron development GO:0021884 7 5 0,000 0,02660024 0,1330012 ! melanosome organization GO:0032438 7 5 0,000 0,02660024 0,13271269 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02660024 0,13242544 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02660024 0,13213942 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02660024 0,13185464 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02660024 0,13157108 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02660024 0,13128874 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02660024 0,13100761 ! nucleoside transport GO:0015858 6 5 0,000 0,02660024 0,13072767 ! nucleoside salvage GO:0043174 7 5 0,000 0,02660024 0,13044894 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02660024 0,13017139 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02660024 0,12989501 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02660024 0,12961981 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02660024 0,12934578 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02660024 0,12907289 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02660024 0,12880116 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02660024 0,12853057 ! depyrimidination GO:0045008 8 5 0,000 0,02660024 0,12826111 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02660024 0,12799279 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02660024 0,12772558 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02660024 0,12745948 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02660024 0,12719449 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02660024 0,12693061 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02660024 0,12666781 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02660024 0,1264061 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02660024 0,12614547 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02660024 0,12588591 ! monocyte differentiation GO:0030224 8 5 0,000 0,02660024 0,12562742 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02660024 0,12536998 ! response to UV-C GO:0010225 6 5 0,000 0,02660024 0,1251136 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02660024 0,12485827 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02660024 0,12460398 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02660024 0,12435071 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02660024 0,12409848 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02660024 0,12384727 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02660024 0,12359707 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02660024 0,12334789 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02660024 0,1230997 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02660024 0,12285251 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02660024 0,12260632 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02660024 0,1223611 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02660024 0,12211687 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02660024 0,12187361 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02660024 0,12163132 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02660024 0,12138998 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02660024 0,12114961 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02660024 0,12091018 ! neural tube patterning GO:0021532 6 5 0,000 0,02660024 0,1206717 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02660024 0,12043416 ! histone demethylation GO:0016577 9 5 0,000 0,02660024 0,12019755 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02660024 0,11996187 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02660024 0,11972711 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02660024 0,11949327 ! enteric nervous system development GO:0048484 8 5 0,000 0,02660024 0,11926033 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02660024 0,11902831 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02660024 0,11879719 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02660024 0,11856696 ! transcription termination GO:0006353 8 5 0,000 0,02660024 0,11833762 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02660024 0,11810917 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02660024 0,1178816 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02660024 0,11765491 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02660024 0,11742908 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02660024 0,11720412 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02660024 0,11698002 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02660024 0,11675678 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02660024 0,11653438 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02660024 0,11631284 ! apical protein localization GO:0045176 6 5 0,000 0,02660024 0,11609213 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02660024 0,11587226 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02660024 0,11565322 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02660024 0,115435 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02660024 0,11521761 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02660024 0,11500104 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02660024 0,11478528 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02660024 0,11457032 ! glial cell migration GO:0008347 10 5 0,000 0,02660024 0,11435617 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02660024 0,11414282 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02660024 0,11393026 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02660024 0,1137185 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02660024 0,11350752 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02660024 0,11329732 ! neural plate development GO:0001840 6 5 0,000 0,02660024 0,1130879 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02660024 0,11287925 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02660024 0,11267137 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02660024 0,11246425 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02660024 0,11225789 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02660024 0,11205229 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02660024 0,11184744 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02660024 0,11164334 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02660024 0,11143998 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02660024 0,11123737 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02660024 0,11103548 ! spindle assembly GO:0051225 5 5 0,000 0,02660024 0,11083433 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02660024 0,11063391 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02660024 0,11043421 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02660024 0,11023523 ! organ regeneration GO:0031100 7 5 0,000 0,02660024 0,11003696 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02660024 0,10983941 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02660024 0,10964257 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02660024 0,10944643 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02660024 0,10925099 GO:0055081|anion homeostasis, ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,02749037 0,1127056 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,02749037 0,11250505 GO:0019724|B cell mediated immunity, ! regulation of angiogenesis GO:0045765 94 49 1,000 0,02856148 0,11668102 ! germ cell development GO:0007281 68 49 1,000 0,02856148 0,11647414 ! regulation of actin filament length GO:0030832 72 50 1,000 0,02964915 0,12069565 ! ear development GO:0043583 72 50 1,000 0,02964915 0,1204824 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,02964915 0,12026991 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 1,000 0,02964915 0,12005817 ! muscle fiber development GO:0048747 74 51 1,000 0,03075315 0,12430975 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,03075315 0,12409167 ! tRNA transcription GO:0009304 11 6 0,000 0,03183567 0,12823474 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03183567 0,12801055 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03183567 0,12778715 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03183567 0,12756452 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03183567 0,12734267 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03183567 0,12712159 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03183567 0,12690128 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03183567 0,12668172 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03183567 0,12646293 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03183567 0,12624489 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03183567 0,1260276 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03183567 0,12581106 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03183567 0,12559526 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03183567 0,1253802 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,03183567 0,12516587 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03183567 0,12495228 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03183567 0,12473941 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03183567 0,12452727 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03183567 0,12431585 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03183567 0,12410515 ! neuron adhesion GO:0007158 9 6 0,000 0,03183567 0,12389515 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,03183567 0,12368587 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03183567 0,1234773 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03183567 0,12326942 ! signal peptide processing GO:0006465 8 6 0,000 0,03183567 0,12306225 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03183567 0,12285577 ! mRNA stabilization GO:0048255 15 6 0,000 0,03183567 0,12264998 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03183567 0,12244488 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03183567 0,12224046 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03183567 0,12203673 ! opsonization GO:0008228 8 6 0,000 0,03183567 0,12183367 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03183567 0,12163129 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03183567 0,12142958 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03183567 0,12122854 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03183567 0,12102816 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03183567 0,12082844 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03183567 0,12062938 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03183567 0,12043098 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03183567 0,12023323 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03183567 0,12003613 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03183567 0,11983967 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03183567 0,11964385 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03183567 0,11944867 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03183567 0,11925413 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03183567 0,11906022 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03183567 0,11886694 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03183567 0,11867429 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03183567 0,11848226 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03183567 0,11829085 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03183567 0,11810006 ! thymic T cell selection GO:0045061 12 6 0,000 0,03183567 0,11790988 ! protein lipoylation GO:0009249 10 6 0,000 0,03183567 0,11772032 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03183567 0,11753136 ! pigment granule organization GO:0048753 11 6 0,000 0,03183567 0,11734301 ! drug transport GO:0015893 6 6 0,000 0,03183567 0,11715526 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03183567 0,11696811 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03183567 0,11678156 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03183567 0,1165956 ! histidine metabolic process GO:0006547 6 6 0,000 0,03183567 0,11641023 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03183567 0,11622545 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03183567 0,11604126 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03183567 0,11585765 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03183567 0,11567462 ! adenohypophysis development GO:0021984 10 6 0,000 0,03183567 0,11549217 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03183567 0,11531029 ! hyperosmotic response GO:0006972 8 6 0,000 0,03183567 0,11512899 ! microtubule nucleation GO:0007020 10 6 0,000 0,03183567 0,11494825 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03183567 0,11476808 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03183567 0,11458848 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03183567 0,11440943 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03183567 0,11423095 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03183567 0,11405302 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,03183567 0,11387564 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03183567 0,11369881 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03183567 0,11352254 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03183567 0,11334681 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03183567 0,11317162 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03183567 0,11299697 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03183567 0,11282286 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03183567 0,11264929 ! organic alcohol transport GO:0015850 9 6 0,000 0,03183567 0,11247625 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03183567 0,11230374 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03183567 0,11213176 ! male sex determination GO:0030238 9 6 0,000 0,03183567 0,1119603 ! carnitine transport GO:0015879 8 6 0,000 0,03183567 0,11178937 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03183567 0,11161896 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03183567 0,11144907 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03183567 0,11127969 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03183567 0,11111083 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03183567 0,11094248 ! parturition GO:0007567 12 6 0,000 0,03183567 0,11077464 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03183567 0,11060731 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03183567 0,11044048 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03183567 0,11027415 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03183567 0,11010833 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03183567 0,109943 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03183567 0,10977817 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03183567 0,10961383 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03183567 0,10944998 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03183567 0,10928662 ! macrophage differentiation GO:0030225 10 6 0,000 0,03183567 0,10912375 ! astrocyte development GO:0014002 14 6 0,000 0,03183567 0,10896136 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03183567 0,10879946 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03183567 0,10863804 ! interaction with symbiont GO:0051702 8 6 0,000 0,03183567 0,10847709 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03183567 0,10831662 ! eating behavior GO:0042755 6 6 0,000 0,03183567 0,10815663 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03183567 0,1079971 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03183567 0,10783805 ! response to copper ion GO:0046688 9 6 0,000 0,03183567 0,10767947 ! DNA topological change GO:0006265 8 6 0,000 0,03183567 0,10752135 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03183567 0,10736369 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03183567 0,1072065 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03183567 0,10704976 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03183567 0,10689348 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03183567 0,10673766 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03183567 0,10658229 ! gas homeostasis GO:0033483 11 6 0,000 0,03183567 0,10642738 ! hair follicle maturation GO:0048820 7 6 0,000 0,03183567 0,10627291 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03183567 0,10611889 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03183567 0,10596532 ! Schwann cell development GO:0014044 14 6 0,000 0,03183567 0,10581219 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03183567 0,1056595 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03183567 0,10550726 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03183567 0,10535545 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03183567 0,10520408 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03183567 0,10505314 ! histone ubiquitination GO:0016574 7 6 0,000 0,03183567 0,10490263 ! regulation of meiosis GO:0040020 10 6 0,000 0,03183567 0,10475256 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03183567 0,10460291 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03183567 0,10445369 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03183567 0,1043049 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03183567 0,10415652 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03183567 0,10400857 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03183567 0,10386104 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03183567 0,10371393 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03183567 0,10356724 ! receptor internalization GO:0031623 9 6 0,000 0,03183567 0,10342096 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03183567 0,10327509 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03183567 0,10312963 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03183567 0,10298458 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03183567 0,10283994 ! protein deubiquitination GO:0016579 8 6 0,000 0,03183567 0,1026957 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03183567 0,10255187 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03183567 0,10240844 ! axonal fasciculation GO:0007413 9 6 0,000 0,03183567 0,10226541 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03183567 0,10212278 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03183567 0,10198055 ! midbrain development GO:0030901 6 6 0,000 0,03183567 0,10183872 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03183567 0,10169727 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03183567 0,10155622 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03183567 0,10141556 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03183567 0,10127529 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03183567 0,10113541 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03183567 0,10099591 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03183567 0,1008568 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03183567 0,10071807 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03183567 0,10057972 ! adult feeding behavior GO:0008343 6 6 0,000 0,03183567 0,10044175 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03183567 0,10030416 ! blastocyst growth GO:0001832 15 6 0,000 0,03183567 0,10016694 ! pigment granule transport GO:0051904 12 6 0,000 0,03183567 0,1000301 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03183567 0,09989364 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03183567 0,09975754 ! catecholamine transport GO:0051937 7 6 0,000 0,03183567 0,09962182 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03183567 0,09948646 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03183567 0,09935147 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03183567 0,09921685 ! protein prenylation GO:0018342 10 6 0,000 0,03183567 0,09908259 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03183567 0,0989487 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,03183567 0,09881516 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03183567 0,09868199 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03183567 0,09854917 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03183567 0,09841672 ! regulation of cellular component size GO:0032535 74 52 1,000 0,03187329 0,09840077 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,03187329 0,09826886 ! establishment of organelle localization GO:0051656 85 52 1,000 0,03187329 0,09813731 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,03300937 0,10149939 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,03416118 0,10490082 ! detection of external stimulus GO:0009581 66 54 1,000 0,03416118 0,10476095 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,03651122 0,11181864 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,03704324 0,11329713 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03704324 0,11314667 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03704324 0,11299661 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03704324 0,11284694 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03704324 0,11269767 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03704324 0,1125488 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03704324 0,11240032 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03704324 0,11225223 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03704324 0,11210453 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03704324 0,11195722 ! reproductive behavior GO:0019098 12 7 0,000 0,03704324 0,11181029 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03704324 0,11166375 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03704324 0,11151759 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03704324 0,11137182 ! oligopeptide transport GO:0006857 11 7 0,000 0,03704324 0,11122642 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03704324 0,11108141 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03704324 0,11093677 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03704324 0,11079251 ! RNA methylation GO:0001510 11 7 0,000 0,03704324 0,11064863 ! pericardium development GO:0060039 8 7 0,000 0,03704324 0,11050511 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03704324 0,11036197 ! fibril organization GO:0043206 13 7 0,000 0,03704324 0,1102192 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03704324 0,1100768 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03704324 0,10993476 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03704324 0,10979309 ! lipoprotein transport GO:0042953 9 7 0,000 0,03704324 0,10965179 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03704324 0,10951085 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03704324 0,10937027 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03704324 0,10923005 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03704324 0,10909019 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03704324 0,10895069 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03704324 0,10881155 ! chemosensory behavior GO:0007635 9 7 0,000 0,03704324 0,10867276 ! microtubule bundle formation GO:0001578 8 7 0,000 0,03704324 0,10853432 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,03704324 0,10839624 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03704324 0,1082585 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03704324 0,10812112 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03704324 0,10798408 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03704324 0,10784739 ! reflex GO:0060004 12 7 0,000 0,03704324 0,10771105 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03704324 0,10757505 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03704324 0,1074394 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03704324 0,10730408 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03704324 0,10716911 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03704324 0,10703447 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03704324 0,10690018 ! spinal cord patterning GO:0021511 7 7 0,000 0,03704324 0,10676622 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03704324 0,10663259 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03704324 0,1064993 ! adrenal gland development GO:0030325 17 7 0,000 0,03704324 0,10636634 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03704324 0,10623372 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03704324 0,10610142 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03704324 0,10596945 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03704324 0,10583782 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03704324 0,1057065 ! endosome organization GO:0007032 10 7 0,000 0,03704324 0,10557552 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03704324 0,10544485 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03704324 0,10531451 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03704324 0,1051845 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03704324 0,1050548 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03704324 0,10492542 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03704324 0,10479636 ! galactose metabolic process GO:0006012 10 7 0,000 0,03704324 0,10466762 ! vesicle fusion GO:0006906 15 7 0,000 0,03704324 0,10453919 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03704324 0,10441108 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03704324 0,10428328 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03704324 0,1041558 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03704324 0,10402862 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03704324 0,10390176 ! retinol metabolic process GO:0042572 9 7 0,000 0,03704324 0,1037752 ! behavioral fear response GO:0001662 13 7 0,000 0,03704324 0,10364896 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03704324 0,10352302 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03704324 0,10339738 ! rRNA modification GO:0000154 12 7 0,000 0,03704324 0,10327205 ! protein heterooligomerization GO:0051291 10 7 0,000 0,03704324 0,10314702 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03704324 0,1030223 ! response to UV-B GO:0010224 11 7 0,000 0,03704324 0,10289788 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03704324 0,10277375 ! intermediate filament organization GO:0045109 11 7 0,000 0,03704324 0,10264993 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03704324 0,1025264 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03704324 0,10240317 ! fibrinolysis GO:0042730 9 7 0,000 0,03704324 0,10228024 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03704324 0,1021576 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03704324 0,10203526 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03704324 0,10191321 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03704324 0,10179145 ! response to tropane GO:0014073 13 7 0,000 0,03704324 0,10166998 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03704324 0,1015488 ! melanosome localization GO:0032400 10 7 0,000 0,03704324 0,10142791 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03704324 0,1013073 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03704324 0,10118699 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03704324 0,10106695 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03704324 0,10094721 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03704324 0,10082774 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03704324 0,10070856 ! mast cell activation GO:0045576 9 7 0,000 0,03704324 0,10058966 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03704324 0,10047104 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03704324 0,1003527 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03704324 0,10023464 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03704324 0,10011685 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,03704324 0,09999934 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03704324 0,09988211 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03704324 0,09976515 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03704324 0,09964847 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03704324 0,09953206 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03704324 0,09941592 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03704324 0,09930005 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03704324 0,09918445 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03704324 0,09906912 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03704324 0,09895406 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03704324 0,09883926 ! diuresis GO:0030146 12 7 0,000 0,03704324 0,09872473 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03704324 0,09861046 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03704324 0,09849646 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03704324 0,09838273 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03704324 0,09826925 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03704324 0,09815604 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03704324 0,09804309 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03704324 0,09793039 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03704324 0,09781796 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03704324 0,09770578 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03704324 0,09759386 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03704324 0,0974822 ! lymph node development GO:0048535 9 7 0,000 0,03704324 0,09737079 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03704324 0,09725964 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03704324 0,09714874 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03704324 0,09703809 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03704324 0,09692769 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03704324 0,09681755 ! ATP catabolic process GO:0006200 10 7 0,000 0,03704324 0,09670765 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03704324 0,09659801 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03704324 0,09648861 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03704324 0,09637946 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03704324 0,09627056 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03704324 0,0961619 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03704324 0,09605349 ! muscle adaptation GO:0043500 12 7 0,000 0,03704324 0,09594532 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03704324 0,09583739 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03704324 0,09572971 ! retina homeostasis GO:0001895 9 7 0,000 0,03704324 0,09562227 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03704324 0,09551507 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03704324 0,09540811 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03704324 0,09530139 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03704324 0,09519491 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03704324 0,09508866 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03704324 0,09498265 ! carbohydrate transport GO:0008643 74 57 1,000 0,03770905 0,0965822 ! chromosome segregation GO:0007059 83 57 1,000 0,03770905 0,09647477 ! camera-type eye development GO:0043010 88 57 1,000 0,03770905 0,09636757 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,03770905 0,09626062 ! gonad development GO:0008406 79 57 1,000 0,03770905 0,0961539 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,03892184 0,09913647 ! lung development GO:0030324 94 59 1,000 0,04014939 0,10214999 ! actin filament organization GO:0007015 95 59 1,000 0,04014939 0,10203712 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,04014939 0,10192449 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,04139151 0,10496192 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04222309 0,10695276 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04222309 0,1068351 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,04222309 0,1067177 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04222309 0,10660055 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04222309 0,10648367 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04222309 0,10636704 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04222309 0,10625066 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04222309 0,10613454 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,04222309 0,10601867 ! phosphate transport GO:0006817 10 8 0,000 0,04222309 0,10590306 ! N-glycan processing GO:0006491 12 8 0,000 0,04222309 0,10578769 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04222309 0,10567258 ! UTP metabolic process GO:0046051 8 8 0,000 0,04222309 0,10555772 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04222309 0,10544311 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04222309 0,10532875 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,04222309 0,10521463 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04222309 0,10510076 ! succinate metabolic process GO:0006105 14 8 0,000 0,04222309 0,10498714 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,04222309 0,10487376 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04222309 0,10476063 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04222309 0,10464774 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04222309 0,1045351 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04222309 0,10442269 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04222309 0,10431053 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04222309 0,10419861 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04222309 0,10408693 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04222309 0,10397549 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04222309 0,10386428 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04222309 0,10375332 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04222309 0,10364259 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04222309 0,10353209 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04222309 0,10342184 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,04222309 0,10331181 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04222309 0,10320202 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04222309 0,10309247 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04222309 0,10298314 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04222309 0,10287405 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04222309 0,10276519 GO:0006559|L-phenylalanine catabolic process, ! melanin metabolic process GO:0006582 12 8 0,000 0,04222309 0,10265656 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04222309 0,10254816 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04222309 0,10243998 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,04222309 0,10233204 ! macrophage activation GO:0042116 12 8 0,000 0,04222309 0,10222432 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04222309 0,10211683 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04222309 0,10200956 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,04222309 0,10190252 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04222309 0,10179571 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04222309 0,10168911 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04222309 0,10158274 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04222309 0,1014766 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04222309 0,10137067 ! ruffle organization GO:0031529 11 8 0,000 0,04222309 0,10126497 ! osteoblast development GO:0002076 13 8 0,000 0,04222309 0,10115948 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04222309 0,10105422 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04222309 0,10094917 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04222309 0,10084434 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04222309 0,10073973 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04222309 0,10063534 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04222309 0,10053116 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04222309 0,1004272 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04222309 0,10032345 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04222309 0,10021992 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,04222309 0,1001166 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,04222309 0,1000135 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04222309 0,0999106 ! segment specification GO:0007379 10 8 0,000 0,04222309 0,09980792 ! cellular extravasation GO:0045123 11 8 0,000 0,04222309 0,09970545 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04222309 0,09960318 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04222309 0,09950113 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04222309 0,09939929 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04222309 0,09929765 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04222309 0,09919622 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04222309 0,099095 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04222309 0,09899399 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04222309 0,09889318 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04222309 0,09879258 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04222309 0,09869218 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04222309 0,09859198 ! icosanoid secretion GO:0032309 12 8 0,000 0,04222309 0,09849199 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04222309 0,0983922 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04222309 0,09829262 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04222309 0,09819323 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04222309 0,09809404 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04222309 0,09799506 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04222309 0,09789627 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04222309 0,09779769 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04222309 0,0976993 ! sterol catabolic process GO:0016127 9 8 0,000 0,04222309 0,09760111 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04222309 0,09750312 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04222309 0,09740532 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04222309 0,09730772 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04222309 0,09721031 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04222309 0,0971131 ! prophase GO:0051324 11 8 0,000 0,04222309 0,09701609 ! S phase GO:0051320 8 8 0,000 0,04222309 0,09691927 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04222309 0,09682264 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04222309 0,0967262 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04222309 0,09662995 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04222309 0,0965339 ! hormone catabolic process GO:0042447 13 8 0,000 0,04222309 0,09643804 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04222309 0,09634236 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04222309 0,09624688 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04222309 0,09615159 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04222309 0,09605648 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04222309 0,09596157 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04222309 0,09586684 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04222309 0,09577229 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04222309 0,09567793 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04222309 0,09558376 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04222309 0,09548978 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04222309 0,09539598 ! regulation of embryonic development GO:0045995 16 8 0,000 0,04222309 0,09530236 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04222309 0,09520893 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04222309 0,09511567 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,04222309 0,09502261 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,04264801 0,09588506 ! extracellular matrix organization GO:0030198 103 61 1,000 0,04264801 0,09579143 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,04264801 0,09569797 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,04264801 0,0956047 ! respiratory tube development GO:0030323 99 62 1,000 0,04391871 0,09835738 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,04391871 0,0982617 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,04391871 0,09816621 ! organelle localization GO:0051640 96 62 1,000 0,04391871 0,0980709 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,04520341 0,10084176 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,04520341 0,10074404 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,04650195 0,10353774 ! respiratory system development GO:0060541 100 64 1,000 0,04650195 0,1034376 ! adaptive immune response GO:0002250 94 64 1,000 0,04650195 0,10333766 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,04737537 0,10517699 ! regulation of developmental growth GO:0048638 13 9 0,000 0,04737537 0,10507556 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,04737537 0,10497433 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04737537 0,1048733 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,04737537 0,10477246 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04737537 0,10467182 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04737537 0,10457136 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,04737537 0,1044711 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04737537 0,10437103 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04737537 0,10427116 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,04737537 0,10417147 ! GTP metabolic process GO:0046039 9 9 0,000 0,04737537 0,10407198 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04737537 0,10397267 ! social behavior GO:0035176 14 9 0,000 0,04737537 0,10387356 ! artery development GO:0060840 19 9 0,000 0,04737537 0,10377463 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04737537 0,10367589 ! regulation of glycolysis GO:0006110 15 9 0,000 0,04737537 0,10357734 ! response to pain GO:0048265 16 9 0,000 0,04737537 0,10347897 ! protein complex disassembly GO:0043241 17 9 0,000 0,04737537 0,1033808 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04737537 0,10328281 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04737537 0,103185 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,04737537 0,10308738 ! lung alveolus development GO:0048286 17 9 0,000 0,04737537 0,10298994 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04737537 0,10289269 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,04737537 0,10279562 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04737537 0,10269874 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04737537 0,10260203 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04737537 0,10250551 ! protein targeting to ER GO:0045047 19 9 0,000 0,04737537 0,10240917 ! T cell selection GO:0045058 18 9 0,000 0,04737537 0,10231301 ! endoderm development GO:0007492 12 9 0,000 0,04737537 0,10221704 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04737537 0,10212124 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,04737537 0,10202562 ! arginine catabolic process GO:0006527 10 9 0,000 0,04737537 0,10193018 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04737537 0,10183492 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04737537 0,10173983 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,04737537 0,10164493 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04737537 0,1015502 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,04737537 0,10145564 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,04737537 0,10136126 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04737537 0,10126706 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04737537 0,10117304 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04737537 0,10107918 ! mannose metabolic process GO:0006013 9 9 0,000 0,04737537 0,1009855 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04737537 0,100892 ! receptor clustering GO:0043113 15 9 0,000 0,04737537 0,10079867 ! epithelial cell development GO:0002064 10 9 0,000 0,04737537 0,10070551 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04737537 0,10061252 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04737537 0,1005197 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,04737537 0,10042706 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04737537 0,10033459 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04737537 0,10024228 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04737537 0,10015015 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,04737537 0,10005818 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,04737537 0,09996638 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,04737537 0,09987476 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04737537 0,0997833 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04737537 0,099692 ! DNA ligation GO:0006266 14 9 0,000 0,04737537 0,09960088 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04737537 0,09950992 ! response to amine stimulus GO:0014075 13 9 0,000 0,04737537 0,09941912 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04737537 0,0993285 ! erythrocyte development GO:0048821 11 9 0,000 0,04737537 0,09923803 ! renal water homeostasis GO:0003091 14 9 0,000 0,04737537 0,09914773 ! postreplication repair GO:0006301 11 9 0,000 0,04737537 0,0990576 ! mRNA cleavage GO:0006379 13 9 0,000 0,04737537 0,09896763 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04737537 0,09887782 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,04737537 0,09878818 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,04737537 0,0986987 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04737537 0,09860938 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04737537 0,09852022 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04737537 0,09843122 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,04737537 0,09834238 ! acid secretion GO:0046717 14 9 0,000 0,04737537 0,09825371 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04737537 0,09816519 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04737537 0,09807683 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04737537 0,09798863 ! purine base metabolic process GO:0006144 18 9 0,000 0,04737537 0,09790059 ! oocyte differentiation GO:0009994 12 9 0,000 0,04737537 0,09781271 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,04737537 0,09772499 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,04737537 0,09763742 ! spleen development GO:0048536 15 9 0,000 0,04737537 0,09755001 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,04737537 0,09746275 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04737537 0,09737566 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04737537 0,09728871 ! detection of calcium ion GO:0005513 13 9 0,000 0,04737537 0,09720193 ! blastocyst formation GO:0001825 12 9 0,000 0,04737537 0,09711529 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04737537 0,09702882 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,04737537 0,09694249 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04737537 0,09685632 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04737537 0,0967703 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04737537 0,09668444 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04737537 0,09659872 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04737537 0,09651316 ! prepulse inhibition GO:0060134 14 9 0,000 0,04737537 0,09642775 ! embryonic placenta development GO:0001892 12 9 0,000 0,04737537 0,09634249 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,04737537 0,09625738 ! insulin secretion GO:0030073 17 9 0,000 0,04737537 0,09617243 ! sequestering of metal ion GO:0051238 11 9 0,000 0,04737537 0,09608762 ! response to nicotine GO:0035094 16 9 0,000 0,04737537 0,09600296 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04737537 0,09591845 ! nucleus localization GO:0051647 15 9 0,000 0,04737537 0,09583409 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04737537 0,09574988 ! localization within membrane GO:0051668 15 9 0,000 0,04737537 0,09566581 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,04781413 0,0964671 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,04781413 0,09638255 ! protein oligomerization GO:0051259 100 65 1,000 0,04781413 0,09629815 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,04913977 0,09888142 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,04913977 0,09879499 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,05250024 0,10545899 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05250024 0,10536697 ! neuron fate specification GO:0048665 11 10 0,000 0,05250024 0,1052751 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05250024 0,1051834 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05250024 0,10509186 ! thyroid gland development GO:0030878 19 10 0,000 0,05250024 0,10500047 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05250024 0,10490925 ! synapsis GO:0007129 13 10 0,000 0,05250024 0,10481818 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05250024 0,10472727 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05250024 0,10463652 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05250024 0,10454592 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05250024 0,10445549 ! sulfate transport GO:0008272 12 10 0,000 0,05250024 0,10436521 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05250024 0,10427508 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,05250024 0,10418511 ! androgen metabolic process GO:0008209 13 10 0,000 0,05250024 0,1040953 ! phospholipid efflux GO:0033700 16 10 0,000 0,05250024 0,10400564 ! hippocampus development GO:0021766 19 10 0,000 0,05250024 0,10391613 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,05250024 0,10382678 ! blood vessel remodeling GO:0001974 21 10 0,000 0,05250024 0,10373758 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05250024 0,10364853 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05250024 0,10355964 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05250024 0,1034709 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05250024 0,10338231 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05250024 0,10329388 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05250024 0,10320559 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,05250024 0,10311746 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,05250024 0,10302947 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05250024 0,10294164 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05250024 0,10285395 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05250024 0,10276642 GO:0005978|glycogen biosynthetic process, ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05250024 0,10267903 ! B cell proliferation GO:0042100 14 10 0,000 0,05250024 0,10259179 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05250024 0,1025047 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05250024 0,10241776 ! forebrain cell migration GO:0021885 17 10 0,000 0,05250024 0,10233097 ! lipid digestion GO:0044241 15 10 0,000 0,05250024 0,10224432 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05250024 0,10215782 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05250024 0,10207146 ! UV protection GO:0009650 14 10 0,000 0,05250024 0,10198526 ! entry into host cell GO:0030260 20 10 0,000 0,05250024 0,10189919 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05250024 0,10181327 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05250024 0,1017275 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05250024 0,10164187 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05250024 0,10155639 ! regulation of bone resorption GO:0045124 24 10 0,000 0,05250024 0,10147104 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,05250024 0,10138585 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05250024 0,10130079 ! regulation of organ growth GO:0046620 11 10 0,000 0,05250024 0,10121588 ! response to dsRNA GO:0043331 18 10 0,000 0,05250024 0,10113111 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05250024 0,10104648 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05250024 0,10096199 ! embryonic axis specification GO:0000578 12 10 0,000 0,05250024 0,10087765 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05250024 0,10079344 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05250024 0,10070938 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05250024 0,10062545 ! cranial nerve development GO:0021545 12 10 0,000 0,05250024 0,10054167 ! fucose catabolic process GO:0019317 16 10 0,000 0,05250024 0,10045802 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,05250024 0,10037452 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05250024 0,10029115 ! protein sumoylation GO:0016925 12 10 0,000 0,05250024 0,10020792 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05250024 0,10012483 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05250024 0,10004187 ! zymogen activation GO:0031638 14 10 0,000 0,05250024 0,09995906 ! salivary gland development GO:0007431 22 10 0,000 0,05250024 0,09987638 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05250024 0,09979384 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05250024 0,09971143 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05250024 0,09962916 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05250024 0,09954703 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,05250024 0,09946503 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05250024 0,09938316 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05250024 0,09930143 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05250024 0,09921984 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05250024 0,09913838 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,05250024 0,09905705 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05250024 0,09897585 ! detection of bacterium GO:0016045 10 10 0,000 0,05250024 0,09889479 ! embryonic gut development GO:0048566 11 10 0,000 0,05250024 0,09881386 ! activation of innate immune response GO:0002218 10 10 0,000 0,05250024 0,09873307 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05250024 0,0986524 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05250024 0,09857187 ! developmental induction GO:0031128 13 10 0,000 0,05250024 0,09849147 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,05250024 0,0984112 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,05250024 0,09833106 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05250024 0,09825105 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05250024 0,09817117 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,05319569 0,09939081 ! response to drug GO:0042493 108 69 1,000 0,05319569 0,09931013 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,05319569 0,09922959 ! eye development GO:0001654 111 70 1,000 0,05457341 0,10171704 ! muscle cell differentiation GO:0042692 104 71 1,000 0,0559637 0,1042239 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,0559637 0,10413958 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,0559637 0,10405539 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,0559637 0,10397134 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,05736641 0,10649132 ! rRNA transcription GO:0009303 17 11 0,000 0,05759782 0,10683466 ! respiratory burst GO:0045730 14 11 0,000 0,05759782 0,10674858 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,05759782 0,10666263 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05759782 0,10657682 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,05759782 0,10649114 ! virus-host interaction GO:0019048 17 11 0,000 0,05759782 0,10640561 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,05759782 0,10632021 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,05759782 0,10623495 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,05759782 0,10614983 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05759782 0,10606484 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05759782 0,10597999 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,05759782 0,10589527 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,05759782 0,10581069 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05759782 0,10572624 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05759782 0,10564193 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,05759782 0,10555776 ! bone resorption GO:0045453 16 11 0,000 0,05759782 0,10547371 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05759782 0,1053898 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05759782 0,10530603 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05759782 0,10522239 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05759782 0,10513888 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05759782 0,1050555 ! syncytium formation GO:0006949 15 11 0,000 0,05759782 0,10497225 ! plasma membrane organization GO:0007009 18 11 0,000 0,05759782 0,10488914 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05759782 0,10480616 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05759782 0,10472331 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05759782 0,10464059 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05759782 0,104558 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05759782 0,10447554 ! adult heart development GO:0007512 11 11 0,000 0,05759782 0,10439321 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,05759782 0,10431101 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,05759782 0,10422894 ! temperature homeostasis GO:0001659 16 11 0,000 0,05759782 0,104147 ! L-glutamate transport GO:0015813 16 11 0,000 0,05759782 0,10406519 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05759782 0,1039835 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05759782 0,10390195 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05759782 0,10382052 ! stem cell development GO:0048864 29 11 0,000 0,05759782 0,10373922 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05759782 0,10365805 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05759782 0,103577 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,05759782 0,10349608 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05759782 0,10341529 ! vasoconstriction GO:0042310 15 11 0,000 0,05759782 0,10333462 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05759782 0,10325408 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05759782 0,10317366 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05759782 0,10309337 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05759782 0,10301321 ! ribosome assembly GO:0042255 13 11 0,000 0,05759782 0,10293317 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05759782 0,10285325 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05759782 0,10277346 ! chromatin silencing GO:0006342 19 11 0,000 0,05759782 0,10269379 ! nucleosome positioning GO:0016584 13 11 0,000 0,05759782 0,10261424 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05759782 0,10253482 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,05759782 0,10245552 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05759782 0,10237634 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05759782 0,10229729 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05759782 0,10221835 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,05759782 0,10213954 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05759782 0,10206085 ! cholesterol efflux GO:0033344 19 11 0,000 0,05759782 0,10198228 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05759782 0,10190383 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,05759782 0,10182551 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05759782 0,1017473 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,05759782 0,10166921 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,05759782 0,10159125 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05759782 0,1015134 ! defense response to fungus GO:0050832 12 11 0,000 0,05759782 0,10143567 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05759782 0,10135806 ! lysogeny GO:0030069 18 11 0,000 0,05759782 0,10128057 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05759782 0,1012032 ! acrosome reaction GO:0007340 13 11 0,000 0,05759782 0,10112594 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05759782 0,10104881 ! regulation of blood pressure GO:0008217 107 73 1,000 0,05878136 0,1030466 ! lactation GO:0007595 20 12 0,000 0,06266827 0,10977686 ! reproductive cellular process GO:0048610 14 12 0,000 0,06266827 0,10969331 ! tRNA modification GO:0006400 14 12 0,000 0,06266827 0,1096099 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,06266827 0,10952661 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06266827 0,10944344 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,06266827 0,10936041 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06266827 0,10927749 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06266827 0,10919471 ! non-recombinational repair GO:0000726 19 12 0,000 0,06266827 0,10911205 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06266827 0,10902951 ! peroxisomal transport GO:0043574 21 12 0,000 0,06266827 0,1089471 ! cartilage condensation GO:0001502 18 12 0,000 0,06266827 0,10886482 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,06266827 0,10878265 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06266827 0,10870062 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,06266827 0,1086187 ! heart looping GO:0001947 15 12 0,000 0,06266827 0,10853691 ! palate development GO:0060021 15 12 0,000 0,06266827 0,10845524 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,06266827 0,1083737 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,06266827 0,10829227 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,06266827 0,10821097 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06266827 0,10812979 ! arginine metabolic process GO:0006525 13 12 0,000 0,06266827 0,10804874 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06266827 0,1079678 ! methionine metabolic process GO:0006555 13 12 0,000 0,06266827 0,10788699 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06266827 0,10780629 ! Golgi organization GO:0007030 18 12 0,000 0,06266827 0,10772572 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,06266827 0,10764527 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06266827 0,10756494 ! monoamine transport GO:0015844 13 12 0,000 0,06266827 0,10748472 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06266827 0,10740463 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,06266827 0,10732466 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06266827 0,1072448 ! L-amino acid transport GO:0015807 20 12 0,000 0,06266827 0,10716507 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06266827 0,10708545 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06266827 0,10700595 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06266827 0,10692657 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06266827 0,10684731 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06266827 0,10676816 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06266827 0,10668913 ! cerebellum development GO:0021549 13 12 0,000 0,06266827 0,10661022 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06266827 0,10653142 ! histone acetylation GO:0016573 23 12 0,000 0,06266827 0,10645274 ! histone methylation GO:0016571 15 12 0,000 0,06266827 0,10637418 ! autonomic nervous system development GO:0048483 23 12 0,000 0,06266827 0,10629573 ! gland morphogenesis GO:0022612 23 12 0,000 0,06266827 0,1062174 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06266827 0,10613919 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,06266827 0,10606109 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06266827 0,1059831 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06266827 0,10590523 ! intestinal absorption GO:0050892 19 12 0,000 0,06266827 0,10582747 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06266827 0,10574983 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06266827 0,1056723 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,06266827 0,10559488 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,06266827 0,10551758 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,06266827 0,10544039 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06266827 0,10536332 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06266827 0,10528635 ! microspike assembly GO:0030035 23 12 0,000 0,06266827 0,1052095 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06266827 0,10513276 ! response to cold GO:0009409 14 12 0,000 0,06266827 0,10505613 ! amine biosynthetic process GO:0009309 97 76 1,000 0,06309797 0,10569943 ! protein ubiquitination GO:0016567 125 77 1,000 0,0645602 0,1080702 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,06771172 0,11326325 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06771172 0,11318093 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06771172 0,11309874 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06771172 0,11301667 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06771172 0,11293471 ! water transport GO:0006833 17 13 0,000 0,06771172 0,11285287 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06771172 0,11277116 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06771172 0,11268956 ! lipid localization GO:0010876 24 13 0,000 0,06771172 0,11260807 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06771172 0,11252671 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06771172 0,11244546 ! organelle fusion GO:0048284 28 13 0,000 0,06771172 0,11236433 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06771172 0,11228332 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06771172 0,11220242 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,06771172 0,11212165 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06771172 0,11204098 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06771172 0,11196044 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06771172 0,11188 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glutamate metabolic process GO:0006536 18 13 0,000 0,06771172 0,11179969 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06771172 0,11171949 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06771172 0,1116394 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06771172 0,11155943 ! NAD metabolic process GO:0019674 21 13 0,000 0,06771172 0,11147957 ! exocrine system development GO:0035272 27 13 0,000 0,06771172 0,11139983 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06771172 0,1113202 ! bone mineralization GO:0030282 15 13 0,000 0,06771172 0,11124069 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06771172 0,11116129 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,06771172 0,111082 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06771172 0,11100283 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06771172 0,11092376 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06771172 0,11084482 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,06771172 0,11076598 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,06771172 0,11068725 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,06771172 0,11060864 ! cellular pigmentation GO:0033059 24 13 0,000 0,06771172 0,11053014 ! tissue regeneration GO:0042246 21 13 0,000 0,06771172 0,11045175 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06771172 0,11037347 ! cofactor transport GO:0051181 19 13 0,000 0,06771172 0,1102953 ! NADP metabolic process GO:0006739 18 13 0,000 0,06771172 0,11021724 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06771172 0,1101393 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06771172 0,11006146 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06771172 0,10998373 ! regulation of RNA stability GO:0043487 28 13 0,000 0,06771172 0,10990612 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06771172 0,10982861 ! regulation of axon extension GO:0030516 23 13 0,000 0,06771172 0,10975121 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06771172 0,10967392 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06771172 0,10959674 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06771172 0,10951967 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06771172 0,1094427 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06771172 0,10936585 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,0690147 0,11139215 GO:0010498|proteasomal protein catabolic process, ! forebrain development GO:0030900 131 80 1,000 0,0690147 0,11131404 ! detection of stimulus GO:0051606 108 82 1,000 0,07203928 0,11611096 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,07272833 0,11713947 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,07272833 0,11705749 ! superoxide anion generation GO:0042554 18 14 0,000 0,07272833 0,11697564 ! neuron maturation GO:0042551 21 14 0,000 0,07272833 0,11689389 ! regulation of S phase GO:0033261 18 14 0,000 0,07272833 0,11681226 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,07272833 0,11673075 ! myotube differentiation GO:0014902 21 14 0,000 0,07272833 0,11664934 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,07272833 0,11656806 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,07272833 0,11648688 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,07272833 0,11640582 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,07272833 0,11632487 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,07272833 0,11624403 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,07272833 0,11616331 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,07272833 0,11608269 ! gene silencing by RNA GO:0031047 20 14 0,000 0,07272833 0,11600219 ! response to cAMP GO:0051591 19 14 0,000 0,07272833 0,1159218 ! limbic system development GO:0021761 25 14 0,000 0,07272833 0,11584152 ! startle response GO:0001964 21 14 0,000 0,07272833 0,11576136 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,07272833 0,1156813 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,07272833 0,11560135 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,07272833 0,11552152 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,07272833 0,11544179 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,07272833 0,11536218 ! glycine metabolic process GO:0006544 22 14 0,000 0,07272833 0,11528267 ! pituitary gland development GO:0021983 23 14 0,000 0,07272833 0,11520328 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,07272833 0,11512399 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,07272833 0,11504481 ! regulation of heart rate GO:0002027 23 14 0,000 0,07272833 0,11496575 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,07272833 0,11488679 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,07272833 0,11480793 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,07272833 0,11472919 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,07272833 0,11465056 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,07272833 0,11457203 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,07272833 0,11449361 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,07272833 0,11441529 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,07272833 0,11433709 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,07272833 0,11425899 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,07272833 0,114181 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07272833 0,11410311 ! mRNA splice site selection GO:0006376 26 14 0,000 0,07272833 0,11402533 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,07272833 0,11394766 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,07272833 0,11387009 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,07272833 0,11379263 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,07272833 0,11371527 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,07272833 0,11363802 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,07272833 0,11356087 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,07272833 0,11348383 ! muscle maintenance GO:0046716 19 14 0,000 0,07272833 0,11340689 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,07272833 0,11333005 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,07272833 0,11325332 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,07272833 0,1131767 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,07272833 0,11310018 ! cell killing GO:0001906 20 14 0,000 0,07272833 0,11302376 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,07272833 0,11294744 ! cilium assembly GO:0042384 20 14 0,000 0,07272833 0,11287123 ! peptide hormone secretion GO:0030072 23 14 0,000 0,07272833 0,11279512 ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,07356756 0,11401981 ! transcription initiation GO:0006352 118 85 1,000 0,07665536 0,11872547 ! regulation of membrane potential GO:0042391 128 85 1,000 0,07665536 0,11864557 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,07771823 0,12020977 ! positive regulation of cell size GO:0045793 20 15 0,000 0,07771823 0,12012898 ! metencephalon development GO:0022037 19 15 0,000 0,07771823 0,1200483 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,07771823 0,11996774 ! skin development GO:0043588 25 15 0,000 0,07771823 0,11988727 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,07771823 0,11980692 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,07771823 0,11972667 ! lipid phosphorylation GO:0046834 23 15 0,000 0,07771823 0,11964654 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,07771823 0,11956651 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,07771823 0,11948658 ! bile acid metabolic process GO:0008206 22 15 0,000 0,07771823 0,11940676 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,07771823 0,11932705 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,07771823 0,11924745 ! adult walking behavior GO:0007628 25 15 0,000 0,07771823 0,11916795 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,07771823 0,11908856 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,07771823 0,11900927 ! myoblast differentiation GO:0045445 27 15 0,000 0,07771823 0,11893009 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,07771823 0,11885101 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,07771823 0,11877204 ! cerebral cortex development GO:0021987 29 15 0,000 0,07771823 0,11869318 ! response to osmotic stress GO:0006970 22 15 0,000 0,07771823 0,11861442 ! vesicle coating GO:0006901 25 15 0,000 0,07771823 0,11853576 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,07771823 0,11845721 ! DNA integration GO:0015074 22 15 0,000 0,07771823 0,11837876 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,07771823 0,11830041 ! peptide secretion GO:0002790 27 15 0,000 0,07771823 0,11822217 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,07771823 0,11814404 ! regulation of vasodilation GO:0042312 24 15 0,000 0,07771823 0,118066 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,07771823 0,11798807 ! neuron recognition GO:0008038 22 15 0,000 0,07771823 0,11791024 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,07771823 0,11783252 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,07771823 0,11775489 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,07771823 0,11767737 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,07771823 0,11759995 ! biomineral formation GO:0031214 18 15 0,000 0,07771823 0,11752263 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,07771823 0,11744542 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,07771823 0,1173683 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,07771823 0,11729129 ! dopamine metabolic process GO:0042417 30 15 0,000 0,07771823 0,11721438 ! organic cation transport GO:0015695 19 15 0,000 0,07771823 0,11713757 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,07771823 0,11706085 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,07771823 0,11698424 ! defense response to virus GO:0051607 27 15 0,000 0,07771823 0,11690773 ! peptide hormone processing GO:0016486 19 15 0,000 0,07771823 0,11683132 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,07771823 0,11675501 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,07978375 0,11977979 GO:0060538|skeletal muscle organ development, ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,08136281 0,12207075 ! protein processing GO:0016485 114 88 1,000 0,08136281 0,12199117 ! protein secretion GO:0009306 27 16 0,000 0,08268156 0,12388768 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,08268156 0,12380702 ! hormone secretion GO:0046879 25 16 0,000 0,08268156 0,12372647 ! bone remodeling GO:0046849 24 16 0,000 0,08268156 0,12364602 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,08268156 0,12356568 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,08268156 0,12348544 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08268156 0,12340531 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,08268156 0,12332528 ! glial cell development GO:0021782 24 16 0,000 0,08268156 0,12324536 ! patterning of blood vessels GO:0001569 24 16 0,000 0,08268156 0,12316553 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,08268156 0,12308582 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,08268156 0,1230062 ! protein polyubiquitination GO:0000209 26 16 0,000 0,08268156 0,12292669 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,08268156 0,12284728 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,08268156 0,12276797 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,08268156 0,12268876 ! fructose metabolic process GO:0006000 20 16 0,000 0,08268156 0,12260966 ! regulation of protein binding GO:0043393 27 16 0,000 0,08268156 0,12253066 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,08268156 0,12245176 ! protein export from nucleus GO:0006611 24 16 0,000 0,08268156 0,12237296 ! negative regulation of immune response GO:0050777 28 16 0,000 0,08268156 0,12229427 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,08268156 0,12221567 ! DNA replication initiation GO:0006270 25 16 0,000 0,08268156 0,12213718 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,08268156 0,12205878 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,08268156 0,12198049 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,08268156 0,1219023 ! diencephalon development GO:0021536 25 16 0,000 0,08268156 0,12182421 ! oogenesis GO:0048477 23 16 0,000 0,08268156 0,12174621 ! neural crest cell migration GO:0001755 24 16 0,000 0,08268156 0,12166832 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,08268156 0,12159053 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,08268156 0,12151283 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,08268156 0,12143524 ! steroid catabolic process GO:0006706 22 16 0,000 0,08268156 0,12135774 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,08268156 0,12128035 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,08268156 0,12120305 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,08268156 0,12112585 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,08268156 0,12104875 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,08268156 0,12097175 ! sperm-egg recognition GO:0035036 16 16 0,000 0,08268156 0,12089484 GO:0007339|binding of sperm to zona pellucida, ! nerve development GO:0021675 18 16 0,000 0,08268156 0,12081803 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,08268156 0,12074132 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,08268156 0,12066471 ! negative regulation of translation GO:0017148 22 16 0,000 0,08268156 0,1205882 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,08295156 0,12090531 ! leukocyte differentiation GO:0002521 143 90 1,000 0,08454987 0,12315687 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,08454987 0,12307892 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,08761846 0,12746519 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,08761846 0,12738461 ! negative regulation of defense response GO:0031348 19 17 0,000 0,08761846 0,12730414 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,08761846 0,12722378 ! glycerol metabolic process GO:0006071 20 17 0,000 0,08761846 0,12714351 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,08761846 0,12706334 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,08761846 0,12698328 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,08761846 0,12690331 ! signal complex assembly GO:0007172 29 17 0,000 0,08761846 0,12682345 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,08761846 0,12674369 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,08761846 0,12666402 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,08761846 0,12658446 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,08761846 0,126505 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,08761846 0,12642563 ! memory GO:0007613 25 17 0,000 0,08761846 0,12634637 ! keratinization GO:0031424 17 17 0,000 0,08761846 0,12626721 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,08761846 0,12618814 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,08761846 0,12610917 ! retinoid metabolic process GO:0001523 22 17 0,000 0,08761846 0,12603031 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,08761846 0,12595154 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,08761846 0,12587287 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,08761846 0,12579429 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,08761846 0,12571582 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,08761846 0,12563744 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,08761846 0,12555916 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,08761846 0,12548098 ! membrane budding GO:0006900 29 17 0,000 0,08761846 0,1254029 ! heme metabolic process GO:0042168 27 17 0,000 0,08761846 0,12532491 ! body fluid secretion GO:0007589 27 17 0,000 0,08761846 0,12524702 ! stem cell differentiation GO:0048863 36 17 0,000 0,08761846 0,12516923 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,08761846 0,12509153 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,08761846 0,12501393 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,08761846 0,12493643 ! sensory perception of pain GO:0019233 23 17 0,000 0,08761846 0,12485902 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,08761846 0,12478171 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,08761846 0,12470449 ! synaptogenesis GO:0007416 24 17 0,000 0,08761846 0,12462737 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,08761846 0,12455035 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,08761846 0,12447342 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,08761846 0,12439658 ! cell-cell junction organization GO:0045216 25 17 0,000 0,08761846 0,12431984 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,08761846 0,12424319 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,08761846 0,12416664 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,08761846 0,12409018 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,08761846 0,12401382 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,08761846 0,12393755 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,08761846 0,12386138 ! sulfur metabolic process GO:0006790 118 92 1,000 0,08777456 0,12400583 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,08940066 0,12622562 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,09252907 0,1305625 ! positive regulation of translation GO:0045727 28 18 0,000 0,09252907 0,13048245 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,09252907 0,13040249 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,09252907 0,13032264 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,09252907 0,13024288 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,09252907 0,13016322 ! cAMP metabolic process GO:0046058 33 18 0,000 0,09252907 0,13008366 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,09252907 0,1300042 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,09252907 0,12992483 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,09252907 0,12984556 ! axis specification GO:0009798 26 18 0,000 0,09252907 0,12976638 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,09252907 0,12968731 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,09252907 0,12960833 ! pancreas development GO:0031016 26 18 0,000 0,09252907 0,12952944 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,09252907 0,12945065 ! glutamine metabolic process GO:0006541 23 18 0,000 0,09252907 0,12937196 ! response to retinoic acid GO:0032526 25 18 0,000 0,09252907 0,12929336 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,09252907 0,12921486 ! fucose metabolic process GO:0006004 26 18 0,000 0,09252907 0,12913645 ! response to fungus GO:0009620 19 18 0,000 0,09252907 0,12905814 ! peptide cross-linking GO:0018149 31 18 0,000 0,09252907 0,12897992 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,09252907 0,1289018 ! heart process GO:0003015 27 18 0,000 0,09252907 0,12882377 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,09252907 0,12874584 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,09252907 0,128668 ! visual learning GO:0008542 35 18 0,000 0,09252907 0,12859025 ! somitogenesis GO:0001756 24 18 0,000 0,09252907 0,1285126 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,09252907 0,12843505 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,09252907 0,12835758 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,09252907 0,12828021 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,09252907 0,12820293 ! vitamin transport GO:0051180 24 18 0,000 0,09252907 0,12812575 ! hormone transport GO:0009914 27 18 0,000 0,09252907 0,12804866 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,09252907 0,12797166 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,09252907 0,12789475 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,09252907 0,12781794 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,09252907 0,12774122 ! cell-cell recognition GO:0009988 20 18 0,000 0,09252907 0,12766459 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,09252907 0,12758805 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,09252907 0,12751161 ! regulation of glucose import GO:0046324 21 18 0,000 0,09252907 0,12743525 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,09252907 0,12735899 ! in utero embryonic development GO:0001701 147 96 1,000 0,09433227 0,1297633 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,09433227 0,12968573 ! protein maturation GO:0051604 129 96 1,000 0,09433227 0,12960826 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,09599345 0,1318119 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,09741354 0,13368206 ! positive regulation of ossification GO:0045778 30 19 0,000 0,09741354 0,13360235 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,09741354 0,13352273 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,09741354 0,1334432 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,09741354 0,13336377 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,09741354 0,13328444 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,09741354 0,13320519 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,09741354 0,13312605 ! regeneration GO:0031099 32 19 0,000 0,09741354 0,13304699 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,09741354 0,13296803 ! sensory perception of taste GO:0050909 23 19 0,000 0,09741354 0,13288917 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,09741354 0,13281039 ! smooth muscle contraction GO:0006939 36 19 0,000 0,09741354 0,13273172 ! peroxisome organization GO:0007031 29 19 0,000 0,09741354 0,13265313 ! digestive system process GO:0022600 30 19 0,000 0,09741354 0,13257464 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,09741354 0,13249624 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,09741354 0,13241793 ! response to vitamin A GO:0033189 26 19 0,000 0,09741354 0,13233971 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,09741354 0,13226159 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,09741354 0,13218356 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,09741354 0,13210562 ! plasma membrane fusion GO:0045026 23 19 0,000 0,09741354 0,13202778 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,09741354 0,13195002 ! cytolysis GO:0019835 20 19 0,000 0,09741354 0,13187236 ! renal system process GO:0003014 35 19 0,000 0,09741354 0,13179479 ! vasodilation GO:0042311 33 19 0,000 0,09741354 0,13171731 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,09741354 0,13163992 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,09741354 0,13156262 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,09741354 0,13148541 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,09741354 0,13140829 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,09741354 0,13133126 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,09741354 0,13125433 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,09741354 0,13117748 ! sarcomere organization GO:0045214 23 19 0,000 0,09741354 0,13110072 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,09741354 0,13102406 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,09741354 0,13094748 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,09741354 0,13087099 GO:0043450|alkene biosynthetic process, ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,09741354 0,13079459 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,09741354 0,13071828 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,09741354 0,13064206 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,10102695 0,13540909 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,10227199 0,136998 ! iron ion transport GO:0006826 37 20 0,000 0,10227199 0,13691826 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,10227199 0,13683861 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,10227199 0,13675905 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,10227199 0,13667959 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,10227199 0,13660022 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,10227199 0,13652094 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,10227199 0,13644175 ! spinal cord development GO:0021510 31 20 0,000 0,10227199 0,13636265 ! response to ethanol GO:0045471 37 20 0,000 0,10227199 0,13628365 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,10227199 0,13620473 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,10227199 0,13612591 ! chromosome condensation GO:0030261 31 20 0,000 0,10227199 0,13604718 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,10227199 0,13596854 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,10227199 0,13588999 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,10227199 0,13581153 ! pallium development GO:0021543 38 20 0,000 0,10227199 0,13573316 ! DNA modification GO:0006304 28 20 0,000 0,10227199 0,13565489 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,10227199 0,1355767 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,10227199 0,1354986 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,10227199 0,13542059 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,10227199 0,13534268 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,10227199 0,13526485 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,10227199 0,13518711 ! collagen catabolic process GO:0030574 25 20 0,000 0,10227199 0,13510946 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,10227199 0,1350319 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,10227199 0,13495443 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,10227199 0,13487705 ! alditol metabolic process GO:0019400 24 20 0,000 0,10227199 0,13479976 ! actin filament-based movement GO:0030048 34 20 0,000 0,10227199 0,13472255 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,10710456 0,14100773 ! regulation of cell killing GO:0031341 34 21 0,000 0,10710456 0,14092706 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,10710456 0,14084648 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,10710456 0,140766 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,10710456 0,14068561 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,10710456 0,14060531 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,10710456 0,1405251 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,10710456 0,14044498 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,10710456 0,14036496 ! protein amino acid acylation GO:0043543 37 21 0,000 0,10710456 0,14028502 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,10710456 0,14020518 ! vesicle docking GO:0048278 27 21 0,000 0,10710456 0,14012542 ! phototransduction GO:0007602 25 21 0,000 0,10710456 0,14004576 ! visual behavior GO:0007632 39 21 0,000 0,10710456 0,13996619 ! ovarian follicle development GO:0001541 30 21 0,000 0,10710456 0,13988671 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,10710456 0,13980732 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,10710456 0,13972802 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,10710456 0,13964881 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,10710456 0,13956969 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,10710456 0,13949066 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,10710456 0,13941171 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,10710456 0,13933286 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,10710456 0,1392541 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,10710456 0,13917542 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,10710456 0,13909684 ! fatty acid transport GO:0015908 30 21 0,000 0,10710456 0,13901834 ! platelet activation GO:0030168 28 21 0,000 0,10710456 0,13893993 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,10710456 0,13886161 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,10710456 0,13878338 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,10710456 0,13870523 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,10710456 0,13862718 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,10710456 0,13854921 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,10710456 0,13847133 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,10710456 0,13839354 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,10710456 0,13831583 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,10710456 0,13823821 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,10710456 0,13816068 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,10710456 0,13808324 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,10710456 0,13800588 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,10710456 0,13792861 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,1119114 0,14403818 ! viral genome replication GO:0019079 29 22 0,000 0,1119114 0,14395762 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,1119114 0,14387715 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,1119114 0,14379677 ! leukocyte adhesion GO:0007159 38 22 0,000 0,1119114 0,14371648 ! molting cycle process GO:0022404 40 22 0,000 0,1119114 0,14363628 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,1119114 0,14355617 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,1119114 0,14347615 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,1119114 0,14339622 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,1119114 0,14331638 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,1119114 0,14323663 ! lysosome organization GO:0007040 37 22 0,000 0,1119114 0,14315696 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,1119114 0,14307739 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,1119114 0,1429979 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,1119114 0,1429185 ! regulation of behavior GO:0050795 38 22 0,000 0,1119114 0,14283919 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,1119114 0,14275997 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,1119114 0,14268083 ! membrane depolarization GO:0051899 35 22 0,000 0,1119114 0,14260178 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,1119114 0,14252282 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,1119114 0,14244395 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,1119114 0,14236517 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,1119114 0,14228647 ! blastocyst development GO:0001824 37 22 0,000 0,1119114 0,14220786 ! neural tube closure GO:0001843 33 22 0,000 0,1119114 0,14212933 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,1119114 0,14205089 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,11669263 0,14803809 ! neuron fate commitment GO:0048663 32 23 0,000 0,11669263 0,14795648 ! embryonic pattern specification GO:0009880 31 23 0,000 0,11669263 0,14787496 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,11669263 0,14779353 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,11669263 0,14771219 ! vesicle targeting GO:0006903 32 23 0,000 0,11669263 0,14763094 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,11669263 0,14754978 ! osteoblast differentiation GO:0001649 40 23 0,000 0,11669263 0,14746871 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,11669263 0,14738773 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,11669263 0,14730684 ! interaction with host GO:0051701 37 23 0,000 0,11669263 0,14722603 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,11669263 0,14714532 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,11669263 0,14706469 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,11669263 0,14698415 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,11669263 0,1469037 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,11669263 0,14682334 ! cell fate determination GO:0001709 45 23 0,000 0,11669263 0,14674306 ! pentose metabolic process GO:0019321 31 23 0,000 0,11669263 0,14666287 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,11669263 0,14658277 ! spermatid development GO:0007286 33 23 0,000 0,11669263 0,14650276 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,11669263 0,14642284 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,11669263 0,146343 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,11669263 0,14626325 ! telomere organization GO:0032200 32 23 0,000 0,11669263 0,14618358 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,11669263 0,146104 ! regulation of amine transport GO:0051952 38 23 0,000 0,11669263 0,14602451 ! liver development GO:0001889 40 23 0,000 0,11669263 0,14594511 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,1214484 0,1518105 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,1214484 0,15172804 ! initiation of viral infection GO:0019059 42 24 0,000 0,1214484 0,15164567 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,1214484 0,15156338 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,1214484 0,15148119 ! superoxide metabolic process GO:0006801 32 24 0,000 0,1214484 0,15139909 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,1214484 0,15131707 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,1214484 0,15123515 ! fat cell differentiation GO:0045444 37 24 0,000 0,1214484 0,15115331 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,1214484 0,15107156 ! sperm motility GO:0030317 27 24 0,000 0,1214484 0,1509899 ! vacuole organization GO:0007033 39 24 0,000 0,1214484 0,15090833 ! receptor metabolic process GO:0043112 37 24 0,000 0,1214484 0,15082684 ! neural crest cell development GO:0014032 39 24 0,000 0,1214484 0,15074545 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,1214484 0,15066414 ! primary neural tube formation GO:0014020 35 24 0,000 0,1214484 0,15058292 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,1214484 0,15050179 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,1214484 0,15042074 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,1214484 0,15033978 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,1214484 0,15025891 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,1214484 0,15017813 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,1214484 0,15009743 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,1214484 0,15001682 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,12617883 0,15577633 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,12617883 0,15569276 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,12617883 0,15560928 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,12617883 0,15552589 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,12617883 0,15544258 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,12617883 0,15535937 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,12617883 0,15527625 ! peptide transport GO:0015833 43 25 0,000 0,12617883 0,15519321 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,12617883 0,15511026 ! phospholipid transport GO:0015914 35 25 0,000 0,12617883 0,15502741 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,12617883 0,15494464 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,12617883 0,15486196 ! detection of light stimulus GO:0009583 30 25 0,000 0,12617883 0,15477936 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,13088406 0,16046553 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,13088406 0,16038004 ! translational initiation GO:0006413 43 26 0,000 0,13088406 0,16029464 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,13088406 0,16020933 ! circadian rhythm GO:0007623 42 26 0,000 0,13088406 0,16012411 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,13088406 0,16003899 ! post-embryonic development GO:0009791 42 26 0,000 0,13088406 0,15995395 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,13088406 0,159869 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,13088406 0,15978415 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,13088406 0,15969938 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,13088406 0,1596147 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,13088406 0,15953012 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,13088406 0,15944562 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,13088406 0,15936121 ! regulation of coagulation GO:0050818 39 26 0,000 0,13088406 0,1592769 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,13556422 0,16488509 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,13556422 0,16479794 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,13556422 0,16471088 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,13556422 0,16462392 ! membrane docking GO:0022406 39 27 0,000 0,13556422 0,16453705 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,13556422 0,16445027 ! catechol metabolic process GO:0009712 43 27 0,000 0,13556422 0,16436358 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,13556422 0,16427698 ! acute-phase response GO:0006953 42 27 0,000 0,13556422 0,16419047 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,13556422 0,16410405 ! myofibril assembly GO:0030239 36 27 0,000 0,13556422 0,16401773 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,13556422 0,16393149 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,13556422 0,16384535 ! natural killer cell activation GO:0030101 35 27 0,000 0,13556422 0,1637593 ! lipid oxidation GO:0034440 38 27 0,000 0,13556422 0,16367334 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,13556422 0,16358746 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,13556422 0,16350168 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,13556422 0,16341599 ! gene silencing GO:0016458 41 27 0,000 0,13556422 0,16333038 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,14021944 0,16885064 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,14021944 0,16876228 ! phenol metabolic process GO:0018958 44 28 0,000 0,14021944 0,16867402 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,14021944 0,16858585 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,14021944 0,16849777 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,14021944 0,16840978 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,14021944 0,16832188 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,14021944 0,16823408 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,14021944 0,16814636 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,14021944 0,16805874 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,14021944 0,16797121 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,14021944 0,16788377 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,14021944 0,16779642 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,14021944 0,16770916 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,14021944 0,167622 ! mesoderm formation GO:0001707 46 28 0,000 0,14021944 0,16753492 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,14021944 0,16744793 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,14021944 0,16736104 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,14021944 0,16727423 ! BMP signaling pathway GO:0030509 40 28 0,000 0,14021944 0,16718752 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,14021944 0,16710089 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,14021944 0,16701436 ! neural tube formation GO:0001841 41 28 0,000 0,14021944 0,16692791 ! placenta development GO:0001890 37 28 0,000 0,14021944 0,16684155 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,14484987 0,17226199 ! regulation of innate immune response GO:0045088 38 29 0,000 0,14484987 0,17217297 ! ovulation cycle process GO:0022602 41 29 0,000 0,14484987 0,17208403 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,14484987 0,17199519 ! protein targeting to membrane GO:0006612 53 29 0,000 0,14484987 0,17190645 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,14484987 0,17181779 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,14484987 0,17172922 ! muscle cell development GO:0055001 38 29 0,000 0,14484987 0,17164075 ! formation of primary germ layer GO:0001704 48 29 0,000 0,14484987 0,17155236 ! telencephalon development GO:0021537 52 29 0,000 0,14484987 0,17146407 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,14484987 0,17137587 ! eye morphogenesis GO:0048592 51 29 0,000 0,14484987 0,17128776 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,14484987 0,17119974 ! collagen metabolic process GO:0032963 40 30 0,000 0,14945561 0,1765526 ! organic anion transport GO:0015711 51 30 0,000 0,14945561 0,17646197 ! cholesterol transport GO:0030301 46 30 0,000 0,14945561 0,17637143 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,14945561 0,17628098 ! spliceosome assembly GO:0000245 49 30 0,000 0,14945561 0,17619063 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,14945561 0,17610036 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,14945561 0,17601019 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,14945561 0,17592012 ! ceramide metabolic process GO:0006672 43 30 0,000 0,14945561 0,17583013 ! ovulation cycle GO:0042698 43 30 0,000 0,14945561 0,17574024 ! hindbrain development GO:0030902 45 30 0,000 0,14945561 0,17565044 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,14945561 0,17556073 ! adult locomotory behavior GO:0008344 47 30 0,000 0,14945561 0,17547111 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,14945561 0,17538159 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,14945561 0,17529215 ! response to heat GO:0009408 41 30 0,000 0,14945561 0,17520281 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,14945561 0,17511356 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,14945561 0,17502439 ! glial cell differentiation GO:0010001 55 31 0,000 0,15403682 0,18029755 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,15403682 0,18020584 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,15403682 0,18011422 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,15403682 0,1800227 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,15403682 0,17993127 ! segmentation GO:0035282 41 31 0,000 0,15403682 0,17983994 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,15403682 0,1797487 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,15403682 0,17965755 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,15403682 0,17956649 ! cell fate specification GO:0001708 37 31 0,000 0,15403682 0,17947552 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,15403682 0,17938465 GO:0060326|cell chemotaxis, ! RNA modification GO:0009451 40 31 0,000 0,15403682 0,17929387 ! regulation of muscle development GO:0048634 48 32 0,000 0,15859361 0,18450445 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,15859361 0,18441117 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,15859361 0,18431799 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,15859361 0,1842249 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,15859361 0,1841319 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,15859361 0,184039 ! cytokine production GO:0001816 44 32 0,000 0,15859361 0,18394619 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,15859361 0,18385348 ! vesicle localization GO:0051648 47 32 0,000 0,15859361 0,18376085 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,16312611 0,18891745 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,16312611 0,18882237 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,16312611 0,18872739 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,16312611 0,18863251 ! actomyosin structure organization GO:0031032 43 33 0,000 0,16312611 0,18853772 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,16312611 0,18844302 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,16312611 0,18834842 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,16312611 0,18825392 ! female gonad development GO:0008585 49 33 0,000 0,16312611 0,18815951 ! positive regulation of cell development GO:0010720 54 33 0,000 0,16312611 0,18806519 ! lipid homeostasis GO:0055088 55 33 0,000 0,16312611 0,18797097 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,16312611 0,18787684 ! regulation of proteolysis GO:0030162 50 33 0,000 0,16312611 0,18778281 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,16312611 0,18768887 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,16312611 0,18759503 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,16763446 0,19268329 ! mRNA catabolic process GO:0006402 48 34 0,000 0,16763446 0,19258704 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,16763446 0,19249089 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,16763446 0,19239484 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,16763446 0,19229888 ! feeding behavior GO:0007631 45 34 0,000 0,16763446 0,19220302 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,16763446 0,19210725 ! female gamete generation GO:0007292 43 34 0,000 0,16763446 0,19201158 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,16763446 0,19191601 ! aerobic respiration GO:0009060 47 34 0,000 0,16763446 0,19182052 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,16763446 0,19172514 ! embryonic organ development GO:0048568 45 34 0,000 0,16763446 0,19162985 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,16763446 0,19153465 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,17211878 0,19656067 ! Notch signaling pathway GO:0007219 56 35 0,000 0,17211878 0,19646312 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,17211878 0,19636567 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,17211878 0,19626831 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,17211878 0,19617105 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,17211878 0,19607389 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,17211878 0,19597682 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,17211878 0,19587985 ! glycogen metabolic process GO:0005977 48 35 0,000 0,17211878 0,19578298 ! pigment metabolic process GO:0042440 61 35 0,000 0,17211878 0,1956862 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,17211878 0,19558952 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,17211878 0,19549293 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,17657919 0,20046009 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,17657919 0,20036119 ! tissue remodeling GO:0048771 62 36 0,000 0,17657919 0,20026239 ! neural tube development GO:0021915 50 36 0,000 0,17657919 0,20016369 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,17657919 0,20006509 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,17657919 0,19996659 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,17657919 0,19986818 ! glucan metabolic process GO:0044042 49 36 0,000 0,17657919 0,19976986 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,18101583 0,20468849 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,18101583 0,20458791 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,18101583 0,20448743 ! learning GO:0007612 67 37 0,000 0,18101583 0,20438704 ! ion transmembrane transport GO:0034220 56 37 0,000 0,18101583 0,20428675 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,18101583 0,20418656 ! regulation of protein secretion GO:0050708 51 37 0,000 0,18101583 0,20408647 ! amino acid activation GO:0043038 52 37 0,000 0,18101583 0,20398648 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,18101583 0,20388658 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,18542881 0,2087549 ! gliogenesis GO:0042063 71 38 0,000 0,18542881 0,20865277 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,18542881 0,20855074 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,18542881 0,20844881 ! phagocytosis GO:0006909 60 38 0,000 0,18542881 0,20834698 ! mesenchymal cell development GO:0014031 64 38 0,000 0,18542881 0,20824525 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 0,000 0,18542881 0,20814361 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,18981827 0,21296684 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,18981827 0,212863 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,18981827 0,21275927 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,18981827 0,21265563 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,18981827 0,2125521 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,18981827 0,21244867 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,18981827 0,21234534 ! chromatin remodeling GO:0006338 68 39 0,000 0,18981827 0,21224211 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,18981827 0,21213898 ! JNK cascade GO:0007254 54 39 0,000 0,18981827 0,21203595 ! developmental growth GO:0048589 62 39 0,000 0,18981827 0,21193302 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,19418432 0,21670254 ! response to calcium ion GO:0051592 58 40 0,000 0,19418432 0,21659745 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,19418432 0,21649246 ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,19418432 0,21638757 ! inner ear development GO:0048839 57 40 0,000 0,19418432 0,21628278 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,19418432 0,21617809 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! JAK-STAT cascade GO:0007259 53 40 0,000 0,19418432 0,21607351 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,19418432 0,21596902 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,1985271 0,22069228 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,1985271 0,22058566 ! striated muscle contraction GO:0006941 62 41 0,000 0,1985271 0,22047915 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,1985271 0,22037274 ! biopolymer methylation GO:0043414 62 41 0,000 0,1985271 0,22026643 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,1985271 0,22016023 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,20284671 0,22484214 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,20284671 0,22473383 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,20284671 0,22462563 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,20284671 0,22451754 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,20284671 0,22440954 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,20284671 0,22430165 ! excretion GO:0007588 63 42 0,000 0,20284671 0,22419387 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,20284671 0,22408619 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,20284671 0,22397861 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,20284671 0,22387113 ! regulation of cell shape GO:0008360 78 42 0,000 0,20284671 0,22376376 ! leukocyte migration GO:0050900 60 43 0,000 0,2071433 0,22839385 ! neuromuscular process GO:0050905 79 43 0,000 0,2071433 0,22828442 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,2071433 0,22817509 ! tRNA processing GO:0008033 49 43 0,000 0,2071433 0,22806586 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,2071433 0,22795674 ! vesicle organization GO:0016050 79 43 0,000 0,2071433 0,22784772 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,2071433 0,22773881 ! methylation GO:0032259 64 43 0,000 0,2071433 0,22763 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,21141697 0,23221539 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,21141697 0,23210455 ! regulation of ion transport GO:0043269 57 44 0,000 0,21141697 0,23199381 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,21141697 0,23188318 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,21141697 0,23177265 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,21141697 0,23166223 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,21141697 0,23155192 ! RNA catabolic process GO:0006401 64 45 0,000 0,21566784 0,23609521 ! positive regulation of defense response GO:0031349 59 45 0,000 0,21566784 0,23598289 ! regulation of translational initiation GO:0006446 64 45 0,000 0,21566784 0,23587068 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,21566784 0,23575857 ! cell recognition GO:0008037 58 45 0,000 0,21566784 0,23564658 ! cell maturation GO:0048469 60 45 0,000 0,21566784 0,23553468 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,21989605 0,2400384 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,21989605 0,23992453 ! cell redox homeostasis GO:0045454 63 46 0,000 0,21989605 0,23981077 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,21989605 0,23969712 ! regulation of ossification GO:0030278 71 46 0,000 0,21989605 0,23958357 ! histone modification GO:0016570 68 46 0,000 0,21989605 0,23947013 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,21989605 0,2393568 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,2241017 0,24381926 ! viral infectious cycle GO:0019058 71 47 0,000 0,2241017 0,24370398 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,2241017 0,24358881 ! endocrine system development GO:0035270 83 47 0,000 0,2241017 0,24347374 ! covalent chromatin modification GO:0016569 75 47 0,000 0,2241017 0,24335879 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,2241017 0,24324394 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,2241017 0,24312921 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,2241017 0,24301458 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,2241017 0,24290006 ! chloride transport GO:0006821 67 48 0,000 0,22828492 0,24731763 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,22828492 0,24720119 ! response to temperature stimulus GO:0009266 62 48 0,000 0,22828492 0,24708486 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,22828492 0,24696864 ! gastrulation GO:0007369 73 48 0,000 0,22828492 0,24685253 ! heart morphogenesis GO:0003007 65 48 0,000 0,22828492 0,24673652 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,22828492 0,24662063 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,22828492 0,24650485 ! regulation of endocytosis GO:0030100 63 48 0,000 0,22828492 0,24638917 ! nuclear export GO:0051168 69 48 0,000 0,22828492 0,2462736 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,22828492 0,24615814 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,23244583 0,25052737 ! sensory perception of smell GO:0007608 61 49 0,000 0,23244583 0,25041003 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,23244583 0,25029279 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,23244583 0,25017567 ! RNA elongation GO:0006354 62 49 0,000 0,23244583 0,25005865 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,23244583 0,24994175 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,23244583 0,24982496 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,23244583 0,24970827 ! cartilage development GO:0051216 70 49 0,000 0,23244583 0,24959169 ! maintenance of location GO:0051235 84 49 0,000 0,23244583 0,24947522 ! membrane fusion GO:0006944 80 50 0,000 0,23658454 0,25379871 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,23658454 0,25368039 ! positive regulation of growth GO:0045927 67 50 0,000 0,23658454 0,25356218 ! proton transport GO:0015992 75 50 0,000 0,23658454 0,25344408 ! hydrogen transport GO:0006818 77 51 0,000 0,24070116 0,25773402 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,24070116 0,25761409 GO:0010863|positive regulation of phospholipase C activity, ! adult behavior GO:0030534 80 51 0,000 0,24070116 0,25749427 ! transition metal ion transport GO:0000041 74 52 0,000 0,24479583 0,26175286 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,24479583 0,26163123 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,24479583 0,26150971 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,24886864 0,26573718 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,24886864 0,26561387 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,24886864 0,26549067 ! single fertilization GO:0007338 59 53 0,000 0,24886864 0,26536759 ! cell projection assembly GO:0030031 76 53 0,000 0,24886864 0,26524462 ! amino acid transport GO:0006865 84 54 0,000 0,25291973 0,26943741 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,25291973 0,26931267 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,25291973 0,26918805 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,25291973 0,26906354 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,25291973 0,26893915 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,25291973 0,26881487 ! exocytosis GO:0006887 74 55 0,000 0,25694919 0,27297143 ! mesoderm development GO:0007498 76 55 0,000 0,25694919 0,27284541 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,25694919 0,2727195 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,25694919 0,2725937 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,26095716 0,27671806 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,26494373 0,28081594 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,26494373 0,28068659 ! secondary metabolic process GO:0019748 84 57 0,000 0,26494373 0,28055736 ! developmental maturation GO:0021700 75 57 0,000 0,26494373 0,28042825 ! viral reproductive process GO:0022415 87 58 0,000 0,26890903 0,28449437 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,26890903 0,28436357 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,26890903 0,28423289 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,27285316 0,2882693 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,27285316 0,28813695 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,27677624 0,29214564 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,27677624 0,29201163 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,27677624 0,29187774 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,27677624 0,29174397 ! regulation of heart contraction GO:0008016 91 60 0,000 0,27677624 0,29161033 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,27677624 0,29147681 ! fertilization GO:0009566 68 60 0,000 0,27677624 0,29134341 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,28067838 0,29531577 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,28067838 0,29518073 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,28067838 0,29504582 ! amine catabolic process GO:0009310 90 62 0,000 0,28455968 0,29898916 ! neurotransmitter transport GO:0006836 81 62 0,000 0,28455968 0,29885263 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,28455968 0,29871623 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,28842027 0,30263075 ! viral reproduction GO:0016032 92 63 0,000 0,28842027 0,30249276 ! regulation of lipase activity GO:0060191 109 63 0,000 0,28842027 0,30235488 ! appendage morphogenesis GO:0035107 93 64 0,000 0,29226024 0,3062408 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,29226024 0,30610134 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,29226024 0,30596202 ! appendage development GO:0048736 94 65 0,000 0,29607971 0,30981953 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 0,000 0,29607971 0,30967864 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,29607971 0,30953788 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,29607971 0,30939724 ! activation of immune response GO:0002253 83 65 0,000 0,29607971 0,30925674 ! antigen processing and presentation GO:0019882 96 66 0,000 0,29987879 0,31308271 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,29987879 0,31294066 ! regulation of immune effector process GO:0002697 101 66 0,000 0,29987879 0,31279873 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,30365758 0,31659675 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,30365758 0,3164533 ! acute inflammatory response GO:0002526 92 68 0,000 0,30741619 0,32022519 ! learning or memory GO:0007611 123 68 0,000 0,30741619 0,32008023 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,30741619 0,3199354 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,30741619 0,31979069 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,30741619 0,31964612 ! rhythmic process GO:0048511 105 68 0,000 0,30741619 0,31950168 ! inorganic anion transport GO:0015698 93 68 0,000 0,30741619 0,31935737 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,31115472 0,3230952 ! response to metal ion GO:0010038 103 70 0,000 0,31487329 0,32680892 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,31487329 0,32666151 ! humoral immune response GO:0006959 86 70 0,000 0,31487329 0,32651423 ! amine transport GO:0015837 101 70 0,000 0,31487329 0,32636709 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,31487329 0,32622008 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,31487329 0,3260732 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,318572 0,329755 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,32225095 0,33341304 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,32225095 0,33326313 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,32225095 0,33311334 ! tube morphogenesis GO:0035239 118 73 0,000 0,32591025 0,33674465 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,32591025 0,33659344 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,32591025 0,33644236 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,32955 0,34004711 ! response to oxygen levels GO:0070482 137 74 0,000 0,32955 0,33989462 ! digestion GO:0007586 97 74 0,000 0,32955 0,33974227 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,32955 0,33959006 ! blood coagulation GO:0007596 116 75 0,000 0,33317031 0,34316691 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,33317031 0,3430133 ! response to nutrient GO:0007584 104 75 0,000 0,33317031 0,34285983 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,33317031 0,34270649 ! tRNA metabolic process GO:0006399 95 76 0,000 0,33677128 0,34625567 ! response to unfolded protein GO:0006986 99 76 0,000 0,33677128 0,34610095 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,33677128 0,34594637 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,340353 0,3494696 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,340353 0,34931365 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,340353 0,34915785 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,340353 0,34900218 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,340353 0,34884666 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,34391559 0,35234114 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,34391559 0,35218426 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,34391559 0,35202752 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,34745914 0,35549645 ! cellular respiration GO:0045333 107 79 0,000 0,34745914 0,35533838 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,34745914 0,35518045 ! regulation of lyase activity GO:0051339 133 79 0,000 0,34745914 0,35502266 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,34745914 0,35486501 ! chromatin assembly GO:0031497 102 80 0,000 0,35098375 0,35830565 GO:0006334|nucleosome assembly, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,35098375 0,35814668 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,35448953 0,3615636 ! hemostasis GO:0007599 125 81 0,000 0,35448953 0,36140333 ! mRNA transport GO:0051028 121 81 0,000 0,35448953 0,3612432 ! response to protein stimulus GO:0051789 111 81 0,000 0,35448953 0,36108322 ! regulation of neurological system process GO:0031644 122 81 0,000 0,35448953 0,36092338 ! vitamin metabolic process GO:0006766 103 81 0,000 0,35448953 0,36076368 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,35448953 0,36060412 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,35797657 0,36399032 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,36144497 0,36735459 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of defense response GO:0031347 117 84 0,000 0,36489483 0,37069705 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,36489483 0,37053338 ! sterol metabolic process GO:0016125 120 84 0,000 0,36489483 0,37036986 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,36832625 0,37368786 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,36832625 0,3735231 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,36832625 0,37335848 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,37173933 0,37665219 ! nucleosome organization GO:0034728 114 87 0,000 0,37513417 0,37992452 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,37513417 0,3797573 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,37513417 0,37959022 ! female pregnancy GO:0007565 130 87 0,000 0,37513417 0,3794233 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,37513417 0,37925652 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,37851085 0,38250217 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,37851085 0,38233419 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,37851085 0,38216635 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,38186948 0,38538824 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,38186948 0,38521921 ! RNA localization GO:0006403 135 91 0,000 0,38853295 0,39176931 ! ATP metabolic process GO:0046034 137 91 0,000 0,38853295 0,39159763 ! response to virus GO:0009615 122 91 0,000 0,38853295 0,3914261 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,39183799 0,39458291 ! positive regulation of immune response GO:0050778 121 92 0,000 0,39183799 0,39441023 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,39512535 0,39754519 ! electron transport chain GO:0022900 123 94 0,000 0,39839513 0,40065973 ! response to oxidative stress GO:0006979 141 94 0,000 0,39839513 0,40048462 ! carboxylic acid transport GO:0046942 147 95 0,000 0,40164742 0,40357758 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,40488232 0,40665037 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,40488232 0,40647287 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,40809991 0,40952435 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,41448355 0,41574887 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,41448355 0,41556764 ! regulation of translation GO:0006417 151 100 0,000 0,41764978 0,41855969 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,41764978 0,41837739 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,41764978 0,41819525 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,41764978 0,41801327 ! divalent metal ion transport GO:0070838 171 100 0,000 0,41764978 0,41783145 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,41764978 0,41764978