pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6614-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cell cycle checkpoint GO:0000075 137 69 8,000 2,055E-11 4,943E-08 ! regulation of protein export from nucleus GO:0046825 10 7 4,000 3,125E-11 3,759E-08 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 5,000 7,519E-11 6,03E-08 ! DNA damage checkpoint GO:0000077 71 33 6,000 1,028E-10 6,183E-08 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 7,000 1,516E-10 7,295E-08 ! DNA integrity checkpoint GO:0031570 75 36 6,000 1,987E-10 7,967E-08 ! DNA damage response, signal transduction GO:0042770 128 60 7,000 2,322E-10 7,98E-08 ! apoptotic mitochondrial changes GO:0008637 41 20 5,000 2,33E-10 7,006E-08 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 4,000 6,779E-10 1,812E-07 GO:0010812|negative regulation of cell-substrate adhesion, ! phospholipid dephosphorylation GO:0046839 12 5 3,000 1,757E-09 4,227E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 5,252E-09 1,149E-06 ! endothelial cell migration GO:0043542 28 17 4,000 8,89E-09 1,782E-06 ! inositol metabolic process GO:0006020 28 17 4,000 8,89E-09 1,645E-06 ! cardiac muscle tissue development GO:0048738 31 17 4,000 8,89E-09 1,528E-06 ! organ growth GO:0035265 15 7 3,000 1,221E-08 1,959E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 1,221E-08 1,837E-06 GO:0046676|negative regulation of insulin secretion, ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 1,221E-08 1,729E-06 ! regulation of protein stability GO:0031647 73 37 5,000 1,315E-08 1,757E-06 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 2,434E-08 3,083E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 2,434E-08 2,929E-06 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 4,367E-08 5,003E-06 ! regulation of cell-matrix adhesion GO:0001952 78 23 4,000 4,733E-08 5,176E-06 GO:0010810|regulation of cell-substrate adhesion, ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 7,254E-08 7,588E-06 ! negative regulation of mast cell proliferation GO:0070667 23 12 3,000 1,698E-07 1,702E-05 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 1,833E-07 1,764E-05 ! cell cycle arrest GO:0007050 213 100 6,000 3,019E-07 2,794E-05 ! oxygen transport GO:0015671 21 14 3,000 3,411E-07 3,039E-05 ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 3,411E-07 2,931E-05 ! negative regulation of cell adhesion GO:0007162 81 35 4,000 4,378E-07 3,632E-05 ! meiosis I GO:0007127 65 37 4,000 5,837E-07 4,681E-05 ! negative regulation of leukocyte proliferation GO:0070664 31 16 3,000 6,16E-07 4,781E-05 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of hormone secretion GO:0046888 25 17 3,000 8,027E-07 6,036E-05 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 3,000 8,027E-07 5,853E-05 ! gas transport GO:0015669 25 17 3,000 8,027E-07 5,681E-05 ! meiosis GO:0007126 121 74 5,000 9,174E-07 6,306E-05 GO:0051327|M phase of meiotic cell cycle, ! polyol metabolic process GO:0019751 66 41 4,000 9,895E-07 6,613E-05 ! meiotic cell cycle GO:0051321 122 75 5,000 9,936E-07 6,461E-05 ! regulation of intracellular protein transport GO:0033157 80 42 4,000 1,119E-06 7,087E-05 ! positive regulation of hormone secretion GO:0046887 32 19 3,000 1,298E-06 8,011E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 1,591E-06 9,568E-05 ! negative regulation of T cell activation GO:0050868 40 20 3,000 1,618E-06 9,492E-05 ! negative regulation of B cell activation GO:0050869 13 6 2,000 1,63E-06 9,339E-05 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 4,000 1,778E-06 9,951E-05 ! cell structure disassembly during apoptosis GO:0006921 30 21 3,000 1,991E-06 1,089E-04 ! mitochondrion organization GO:0007005 148 86 5,000 2,23E-06 1,192E-04 ! apoptotic nuclear changes GO:0030262 32 22 3,000 2,426E-06 1,269E-04 ! regulation of cell adhesion GO:0030155 212 89 5,000 2,727E-06 1,396E-04 ! regulation of helicase activity GO:0051095 15 7 2,000 2,844E-06 1,425E-04 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 3,000 3,5E-06 1,718E-04 ! regulation of insulin secretion GO:0050796 37 25 3,000 4,152E-06 1,998E-04 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 4,507E-06 2,126E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 4,535E-06 2,098E-04 ! dendrite morphogenesis GO:0048813 13 8 2,000 4,535E-06 2,059E-04 ! regulation of intracellular transport GO:0032386 101 57 4,000 5,227E-06 2,329E-04 ! negative regulation of lymphocyte activation GO:0051250 53 27 3,000 5,722E-06 2,503E-04 ! axon extension GO:0048675 15 9 2,000 6,781E-06 2,913E-04 ! regulation of peptide secretion GO:0002791 47 29 3,000 7,691E-06 3,246E-04 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 8,844E-06 3,669E-04 ! negative regulation of leukocyte activation GO:0002695 56 30 3,000 8,844E-06 3,606E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 9,656E-06 3,872E-04 ! central nervous system neuron axonogenesis GO:0021955 22 10 2,000 9,656E-06 3,809E-04 GO:0021952|central nervous system projection neuron axonogenesis, ! triglyceride metabolic process GO:0006641 43 31 3,000 1,012E-05 3,927E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 1,164E-05 4,445E-04 ! activation of MAPK activity GO:0000187 115 67 4,000 1,164E-05 4,376E-04 ! negative regulation of kinase activity GO:0033673 131 68 4,000 1,252E-05 4,634E-04 ! negative regulation of transferase activity GO:0051348 140 72 4,000 1,657E-05 6,041E-04 ! negative regulation of secretion GO:0051048 63 35 3,000 1,661E-05 5,966E-04 ! neutral lipid metabolic process GO:0006638 50 35 3,000 1,661E-05 5,878E-04 GO:0006639|acylglycerol metabolic process, ! regulation of B cell proliferation GO:0030888 20 12 2,000 1,759E-05 6,133E-04 ! negative regulation of cell activation GO:0050866 65 36 3,000 1,863E-05 6,402E-04 ! glycerol ether metabolic process GO:0006662 53 37 3,000 2,081E-05 7,053E-04 ! carbohydrate homeostasis GO:0033500 53 38 3,000 2,318E-05 7,747E-04 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 3,000 2,318E-05 7,641E-04 ! organic ether metabolic process GO:0018904 55 39 3,000 2,574E-05 8,37E-04 ! regulation of hormone secretion GO:0046883 62 40 3,000 2,851E-05 9,145E-04 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 3,12E-05 9,878E-04 ! hormone-mediated signaling GO:0009755 74 41 3,000 3,148E-05 9,837E-04 ! regulation of T cell proliferation GO:0042129 71 41 3,000 3,148E-05 9,711E-04 ! negative regulation of transport GO:0051051 153 84 4,000 3,506E-05 1,068E-03 ! regulation of protein transport GO:0051223 154 87 4,000 4,152E-05 1,249E-03 GO:0070201|regulation of establishment of protein localization, ! negative regulation of cell migration GO:0030336 115 46 3,000 4,988E-05 1,482E-03 ! cellular component disassembly GO:0022411 86 48 3,000 5,907E-05 1,733E-03 ! activation of caspase activity GO:0006919 84 48 3,000 5,907E-05 1,712E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 5,907E-05 1,692E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 6,331E-05 1,792E-03 ! negative regulation of immune system process GO:0002683 95 50 3,000 6,944E-05 1,943E-03 ! regulation of protein localization GO:0032880 176 97 4,000 6,993E-05 1,934E-03 ! interphase GO:0051325 213 98 4,000 7,343E-05 2,008E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 7,51E-05 2,03E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! response to UV GO:0009411 104 53 3,000 8,741E-05 2,337E-03 ! positive regulation of caspase activity GO:0043280 95 55 3,000 1,011E-04 2,673E-03 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 3,000 1,011E-04 2,644E-03 ! regulation of multicellular organism growth GO:0040014 85 55 3,000 1,011E-04 2,616E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 1,011E-04 2,588E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 1,033E-04 2,616E-03 ! lipid modification GO:0030258 97 57 3,000 1,163E-04 2,915E-03 ! central nervous system neuron development GO:0021954 46 22 2,000 1,192E-04 2,958E-03 ! positive regulation of secretion GO:0051047 95 59 3,000 1,331E-04 3,268E-03 ! DNA catabolic process GO:0006308 86 59 3,000 1,331E-04 3,235E-03 ! regulation of DNA recombination GO:0000018 48 23 2,000 1,367E-04 3,289E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 1,421E-04 3,386E-03 ! central nervous system neuron differentiation GO:0021953 50 24 2,000 1,557E-04 3,673E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 1,764E-04 4,12E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 1,764E-04 4,08E-03 ! multicellular organism reproduction GO:0032504 111 64 3,000 1,827E-04 4,187E-03 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of helicase activity GO:0051096 11 5 1,000 1,89E-04 4,29E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,89E-04 4,25E-03 ! skeletal myofibril assembly GO:0014866 10 5 1,000 1,89E-04 4,211E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,89E-04 4,172E-03 ! cardiac muscle fiber development GO:0048739 10 5 1,000 1,89E-04 4,134E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,89E-04 4,097E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 1,89E-04 4,06E-03 ! B cell homeostasis GO:0001782 13 5 1,000 1,89E-04 4,024E-03 ! stem cell division GO:0017145 11 5 1,000 1,89E-04 3,989E-03 GO:0048103|somatic stem cell division, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 1,987E-04 4,158E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 2,182E-04 4,526E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 2,229E-04 4,583E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 2,229E-04 4,544E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 2,444E-04 4,942E-03 ! urogenital system development GO:0001655 137 69 3,000 2,444E-04 4,901E-03 ! dendrite development GO:0016358 59 28 2,000 2,488E-04 4,948E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 2,488E-04 4,907E-03 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 2,827E-04 5,53E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 2,827E-04 5,485E-03 ! neuron apoptosis GO:0051402 9 6 1,000 2,827E-04 5,441E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 2,827E-04 5,398E-03 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 2,827E-04 5,356E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,827E-04 5,314E-03 ! determination of adult lifespan GO:0008340 15 6 1,000 2,827E-04 5,273E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 2,88E-04 5,33E-03 ! phosphoinositide metabolic process GO:0030384 128 72 3,000 2,88E-04 5,289E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 3,064E-04 5,585E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 3,199E-04 5,787E-03 ! prostate gland development GO:0030850 13 7 1,000 3,946E-04 7,086E-03 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 3,946E-04 7,033E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 3,946E-04 6,982E-03 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 3,946E-04 6,931E-03 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 3,946E-04 6,88E-03 ! centrosome duplication GO:0051298 13 7 1,000 3,946E-04 6,831E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 3,946E-04 6,782E-03 ! anterograde axon cargo transport GO:0008089 18 7 1,000 3,946E-04 6,734E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 3,946E-04 6,687E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 3,946E-04 6,64E-03 ! response to tumor cell GO:0002347 13 7 1,000 3,946E-04 6,594E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 4,107E-04 6,815E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 4,861E-04 8,011E-03 ! negative regulation of growth GO:0045926 155 84 3,000 5,186E-04 8,489E-03 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 1,000 5,247E-04 8,53E-03 GO:0016446|somatic hypermutation of immunoglobulin genes, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 5,247E-04 8,472E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 5,247E-04 8,416E-03 ! ER overload response GO:0006983 12 8 1,000 5,247E-04 8,36E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 5,247E-04 8,305E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 5,247E-04 8,251E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,247E-04 8,197E-03 ! multicellular organismal aging GO:0010259 18 8 1,000 5,247E-04 8,144E-03 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 6,701E-04 0,01033529 ! elastic fiber assembly GO:0048251 15 9 1,000 6,726E-04 0,01030818 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 6,726E-04 0,01024294 ! middle ear morphogenesis GO:0042474 14 9 1,000 6,726E-04 0,01017852 ! motor axon guidance GO:0008045 16 9 1,000 6,726E-04 0,0101149 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 6,726E-04 0,01005208 ! regulation of telomere maintenance GO:0032204 14 9 1,000 6,726E-04 9,99E-03 ! regulation of cell cycle process GO:0010564 149 90 3,000 6,731E-04 9,935E-03 ! sex differentiation GO:0007548 145 90 3,000 6,731E-04 9,874E-03 ! regulation of T cell differentiation GO:0045580 70 41 2,000 7,767E-04 0,01132521 ! regulation of T cell activation GO:0050863 158 94 3,000 7,925E-04 0,01148668 ! neuron migration GO:0001764 79 42 2,000 8,337E-04 0,01201189 ! pathogenesis GO:0009405 13 10 1,000 8,384E-04 0,01200698 ! polyamine biosynthetic process GO:0006596 12 10 1,000 8,384E-04 0,01193593 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 8,384E-04 0,01186572 ! hormone metabolic process GO:0042445 157 97 3,000 8,914E-04 0,01254213 ! striated muscle cell differentiation GO:0051146 82 43 2,000 8,934E-04 0,01249743 ! male sex differentiation GO:0046661 76 44 2,000 9,557E-04 0,01329184 ! glycolysis GO:0006096 65 45 2,000 1,021E-03 0,01411427 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,022E-03 0,01404775 ! T cell proliferation GO:0042098 26 11 1,000 1,022E-03 0,01396794 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,022E-03 0,01388902 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 1,022E-03 0,013811 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,088E-03 0,01463046 ! pigmentation GO:0043473 100 46 2,000 1,088E-03 0,01454918 ! endosome transport GO:0016197 108 47 2,000 1,159E-03 0,01540606 ! polyamine metabolic process GO:0006595 17 12 1,000 1,223E-03 0,01616244 ! focal adhesion formation GO:0048041 35 12 1,000 1,223E-03 0,01607412 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 1,223E-03 0,01598676 ! T cell homeostasis GO:0043029 25 12 1,000 1,223E-03 0,01590035 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 1,232E-03 0,01594044 ! response to X-ray GO:0010165 25 13 1,000 1,441E-03 0,01853702 ! regulation of cellular pH GO:0030641 22 13 1,000 1,441E-03 0,01843842 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 1,441E-03 0,01834087 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 2,000 1,643E-03 0,02080116 ! regulation of mRNA processing GO:0050684 24 14 1,000 1,676E-03 0,02111291 ! response to gamma radiation GO:0010332 28 14 1,000 1,676E-03 0,02100295 ! male genitalia development GO:0030539 24 14 1,000 1,676E-03 0,02089412 ! glucose catabolic process GO:0006007 82 55 2,000 1,828E-03 0,02267016 ! regulation of protein catabolic process GO:0042176 116 55 2,000 1,828E-03 0,0225539 ! regulation of actin filament length GO:0030832 105 56 2,000 1,925E-03 0,02363355 ! regulation of DNA replication GO:0006275 101 56 2,000 1,925E-03 0,02351358 ! positive regulation of organelle organization GO:0010638 100 56 2,000 1,925E-03 0,02339482 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,928E-03 0,02331469 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,928E-03 0,02319812 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,928E-03 0,02308271 ! positive regulation of cell migration GO:0030335 126 57 2,000 2,026E-03 0,02412856 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 2,198E-03 0,02604549 ! activation of MAPKK activity GO:0000186 35 16 1,000 2,198E-03 0,02591782 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 2,198E-03 0,02579139 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 2,198E-03 0,02566619 ! axon cargo transport GO:0008088 43 16 1,000 2,198E-03 0,0255422 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,198E-03 0,0254194 ! regulation of cellular component size GO:0032535 109 59 2,000 2,236E-03 0,02574544 ! camera-type eye development GO:0043010 116 60 2,000 2,347E-03 0,02688569 ! kidney development GO:0001822 122 60 2,000 2,347E-03 0,02675827 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 2,483E-03 0,02818413 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,483E-03 0,02805181 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,483E-03 0,02792073 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,483E-03 0,02779086 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 2,483E-03 0,0276622 ! genitalia development GO:0048806 30 17 1,000 2,483E-03 0,02753473 ! regulation of mitosis GO:0007088 105 63 2,000 2,697E-03 0,02976935 GO:0051783|regulation of nuclear division, ! centrosome cycle GO:0007098 25 18 1,000 2,786E-03 0,03060579 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,786E-03 0,03046668 ! positive regulation of cell motion GO:0051272 146 64 2,000 2,821E-03 0,0307116 ! extracellular matrix organization GO:0030198 133 66 2,000 3,079E-03 0,03336607 ! actin filament bundle formation GO:0051017 42 19 1,000 3,105E-03 0,03349675 ! pigmentation during development GO:0048066 41 19 1,000 3,105E-03 0,03334721 ! neuromuscular junction development GO:0007528 34 19 1,000 3,105E-03 0,033199 ! G1 phase GO:0051318 40 19 1,000 3,105E-03 0,03305211 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 3,105E-03 0,0329065 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 3,105E-03 0,03276217 ! homeostasis of number of cells GO:0048872 114 67 2,000 3,213E-03 0,03375491 ! hexose catabolic process GO:0019320 104 67 2,000 3,213E-03 0,03360815 ! response to alkaloid GO:0043279 38 20 1,000 3,44E-03 0,03582685 ! cellular response to starvation GO:0009267 33 20 1,000 3,44E-03 0,03567242 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 3,44E-03 0,03551932 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 3,44E-03 0,03536753 ! reproductive structure development GO:0048608 113 71 2,000 3,785E-03 0,03874887 ! B cell activation GO:0042113 160 71 2,000 3,785E-03 0,03858468 ! smooth muscle contraction GO:0006939 46 21 1,000 3,791E-03 0,03848522 ! cell aging GO:0007569 44 21 1,000 3,791E-03 0,03832352 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 3,791E-03 0,03816317 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 3,791E-03 0,03800415 ! axon guidance GO:0007411 139 73 2,000 4,092E-03 0,04085642 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 4,158E-03 0,04134053 ! microtubule-based transport GO:0010970 54 22 1,000 4,158E-03 0,0411704 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,158E-03 0,04100167 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 4,158E-03 0,04083432 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 4,158E-03 0,04066833 ! activation of JUN kinase activity GO:0007257 42 22 1,000 4,158E-03 0,04050368 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 4,158E-03 0,04034035 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 4,158E-03 0,04017835 ! protein stabilization GO:0050821 39 22 1,000 4,158E-03 0,04001763 ! regulation of transcription factor activity GO:0051090 126 74 2,000 4,252E-03 0,04075665 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 149 74 2,000 4,252E-03 0,04059492 ! eye development GO:0001654 143 74 2,000 4,252E-03 0,04043446 ! positive regulation of DNA replication GO:0045740 43 23 1,000 4,541E-03 0,04301531 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 4,541E-03 0,04284662 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 4,541E-03 0,04267925 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 4,541E-03 0,04251319 ! sex determination GO:0007530 47 23 1,000 4,541E-03 0,04234841 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 4,541E-03 0,0421849 ! negative regulation of catabolic process GO:0009895 50 23 1,000 4,541E-03 0,04202265 ! development of primary sexual characteristics GO:0045137 124 76 2,000 4,582E-03 0,0422372 ! monosaccharide catabolic process GO:0046365 115 76 2,000 4,582E-03 0,04207599 ! regulation of catabolic process GO:0009894 161 76 2,000 4,582E-03 0,041916 ! regulation of actin filament-based process GO:0032970 152 77 2,000 4,752E-03 0,04331248 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 4,94E-03 0,04484941 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,94E-03 0,0446808 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 4,94E-03 0,04451346 GO:0016444|somatic cell DNA recombination, ! lymphocyte proliferation GO:0046651 48 24 1,000 4,94E-03 0,04434736 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,94E-03 0,0441825 ! leukocyte homeostasis GO:0001776 44 24 1,000 4,94E-03 0,04401887 ! protein tetramerization GO:0051262 52 24 1,000 4,94E-03 0,04385643 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 5,105E-03 0,0451586 ! muscle cell differentiation GO:0042692 159 80 2,000 5,287E-03 0,04659821 ! protein import into nucleus GO:0006606 158 80 2,000 5,287E-03 0,04642814 ! myelination GO:0042552 45 25 1,000 5,354E-03 0,04684247 ! vasculogenesis GO:0001570 46 25 1,000 5,354E-03 0,04667275 ! negative regulation of DNA replication GO:0008156 42 25 1,000 5,354E-03 0,04650426 ! response to starvation GO:0042594 42 25 1,000 5,354E-03 0,04633697 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,354E-03 0,04617089 ! negative regulation of cell development GO:0010721 73 25 1,000 5,354E-03 0,046006 GO:0050768|negative regulation of neurogenesis, ! immunoglobulin production GO:0002377 55 25 1,000 5,354E-03 0,04584227 GO:0002440|production of molecular mediator of immune response, ! cellular response to nutrient levels GO:0031669 41 25 1,000 5,354E-03 0,04567971 ! T cell activation GO:0042110 168 81 2,000 5,473E-03 0,04653282 ! nuclear import GO:0051170 161 81 2,000 5,473E-03 0,04636897 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 5,784E-03 0,04882563 ! microtubule organizing center organization GO:0031023 39 26 1,000 5,784E-03 0,04865491 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 1,000 5,784E-03 0,04848538 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,784E-03 0,04831703 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 5,784E-03 0,04814984 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 56 26 1,000 5,784E-03 0,04798381 ! leukocyte proliferation GO:0070661 52 26 1,000 5,784E-03 0,04781891 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 5,784E-03 0,04765515 ! regulation of ligase activity GO:0051340 142 84 2,000 6,055E-03 0,04971867 ! mitochondrial membrane organization GO:0007006 57 27 1,000 6,228E-03 0,05097153 ! male gonad development GO:0008584 44 27 1,000 6,228E-03 0,05079875 ! base-excision repair GO:0006284 41 27 1,000 6,228E-03 0,05062713 ! glutathione metabolic process GO:0006749 39 27 1,000 6,228E-03 0,05045667 ! alcohol catabolic process GO:0046164 130 86 2,000 6,462E-03 0,052173 ! protein localization in nucleus GO:0034504 176 87 2,000 6,672E-03 0,05368539 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,688E-03 0,05364107 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 6,688E-03 0,05346286 ! regulation of DNA binding GO:0051101 155 88 2,000 6,885E-03 0,05485416 ! gland development GO:0048732 206 88 2,000 6,885E-03 0,05467312 ! regulation of pH GO:0006885 43 29 1,000 7,163E-03 0,05669421 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 7,163E-03 0,05650833 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 7,163E-03 0,05632366 ! tissue homeostasis GO:0001894 48 29 1,000 7,163E-03 0,0561402 GO:0048871|multicellular organismal homeostasis, ! cell junction assembly GO:0034329 78 30 1,000 7,653E-03 0,05978396 ! myofibril assembly GO:0030239 47 30 1,000 7,653E-03 0,05959048 GO:0055002|striated muscle cell development, ! ensheathment of neurons GO:0007272 57 30 1,000 7,653E-03 0,05939825 GO:0008366|axon ensheathment, ! iron ion homeostasis GO:0055072 54 31 1,000 8,158E-03 0,06311011 ! erythrocyte differentiation GO:0030218 55 31 1,000 8,158E-03 0,06290784 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 8,158E-03 0,06270685 GO:0043433|negative regulation of transcription factor activity, ! forebrain development GO:0030900 188 95 2,000 8,495E-03 0,06508896 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 8,677E-03 0,06627324 ! spindle organization GO:0007051 46 32 1,000 8,677E-03 0,06606351 ! metanephros development GO:0001656 74 32 1,000 8,677E-03 0,06585511 ! response to ionizing radiation GO:0010212 65 32 1,000 8,677E-03 0,06564802 ! response to mechanical stimulus GO:0009612 57 32 1,000 8,677E-03 0,06544223 ! muscle cell development GO:0055001 49 32 1,000 8,677E-03 0,06523772 ! peripheral nervous system development GO:0007422 64 32 1,000 8,677E-03 0,06503449 ! positive regulation of catabolic process GO:0009896 64 32 1,000 8,677E-03 0,06483252 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 9,21E-03 0,06860561 ! negative regulation of protein transport GO:0051224 69 33 1,000 9,21E-03 0,06839386 ! mismatch repair GO:0006298 46 34 1,000 9,758E-03 0,07223859 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 9,758E-03 0,072017 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 9,758E-03 0,07179676 ! odontogenesis GO:0042476 66 35 1,000 0,01031984 0,07569982 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01031984 0,07546973 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,0108958 0,07944028 ! cell junction organization GO:0034330 86 36 1,000 0,0108958 0,07920028 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,0108958 0,07896173 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01148565 0,08298642 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01148565 0,08273795 ! actomyosin structure organization GO:0031032 62 37 1,000 0,01148565 0,08249098 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01148565 0,08224547 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01148565 0,08200142 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,01148565 0,08175881 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01208927 0,08580171 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01208927 0,08554935 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01208927 0,08529847 ! mammary gland development GO:0030879 86 39 1,000 0,01270652 0,08939148 ! ear morphogenesis GO:0042471 60 39 1,000 0,01270652 0,08913086 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01270652 0,08887176 ! negative regulation of binding GO:0051100 72 40 1,000 0,01333728 0,093013 ! cytokinesis GO:0000910 72 40 1,000 0,01333728 0,09274418 ! T cell differentiation GO:0030217 81 41 1,000 0,01398141 0,09694315 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01398141 0,09666457 ! regulation of tube size GO:0035150 71 42 1,000 0,01463879 0,10091959 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,01463879 0,10063125 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01463879 0,10034455 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01463879 0,10005948 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 79 43 1,000 0,0153093 0,1043461 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,0153093 0,10405134 ! glucose transport GO:0015758 65 43 1,000 0,0153093 0,10375824 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,0153093 0,10346678 ! striated muscle contraction GO:0006941 77 43 1,000 0,0153093 0,10317696 ! hexose transport GO:0008645 67 44 1,000 0,0159928 0,10748236 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 1,000 0,0159928 0,10718296 ! B cell differentiation GO:0030183 107 44 1,000 0,0159928 0,10688523 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,01668918 0,11123037 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01668918 0,1109231 ! cell growth GO:0016049 84 45 1,000 0,01668918 0,11061753 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,0173983 0,11500086 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,0173983 0,11468579 ! response to insulin stimulus GO:0032868 95 46 1,000 0,0173983 0,11437244 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01812005 0,11879247 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01812005 0,11846967 ! JNK cascade GO:0007254 91 47 1,000 0,01812005 0,11814861 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01812005 0,11782929 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,0188543 0,12227343 ! mitochondrial transport GO:0006839 82 48 1,000 0,0188543 0,12194474 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,0188543 0,12161781 ! regulation of action potential GO:0001508 95 49 1,000 0,01960093 0,12609582 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,01960093 0,12575956 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,01960093 0,12542509 ! peptide metabolic process GO:0006518 76 49 1,000 0,01960093 0,1250924 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,01960093 0,12476147 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01960093 0,12443228 ! positive regulation of binding GO:0051099 78 51 1,000 0,02113085 0,13379163 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,02113085 0,13344047 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0217247 0,13683152 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0217247 0,13647426 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0217247 0,13611885 ! neuron fate determination GO:0048664 7 5 0,000 0,0217247 0,1357653 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0217247 0,13541357 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0217247 0,13506367 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0217247 0,13471557 ! polyol transport GO:0015791 12 5 0,000 0,0217247 0,13436925 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0217247 0,13402472 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0217247 0,13368194 ! response to superoxide GO:0000303 10 5 0,000 0,0217247 0,13334092 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0217247 0,13300163 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0217247 0,13266406 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0217247 0,1323282 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0217247 0,13199404 ! female meiosis GO:0007143 7 5 0,000 0,0217247 0,13166156 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0217247 0,13133075 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0217247 0,1310016 ! cobalt ion transport GO:0006824 11 5 0,000 0,0217247 0,1306741 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0217247 0,13034823 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0217247 0,13002398 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0217247 0,12970134 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0217247 0,1293803 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0217247 0,12906084 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0217247 0,12874296 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0217247 0,12842663 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0217247 0,12811186 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0217247 0,12779863 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0217247 0,12748693 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0217247 0,12717674 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0217247 0,12686806 ! negative chemotaxis GO:0050919 14 5 0,000 0,0217247 0,12656087 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0217247 0,12625517 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0217247 0,12595094 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0217247 0,12564817 ! behavioral response to pain GO:0048266 9 5 0,000 0,0217247 0,12534686 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0217247 0,12504699 ! Notch receptor processing GO:0007220 8 5 0,000 0,0217247 0,12474854 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0217247 0,12445152 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0217247 0,12415591 ! micturition GO:0060073 9 5 0,000 0,0217247 0,12386171 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0217247 0,12356889 ! copulation GO:0007620 9 5 0,000 0,0217247 0,12327745 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0217247 0,12298739 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0217247 0,12269868 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0217247 0,12241133 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0217247 0,12212533 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0217247 0,12184065 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0217247 0,1215573 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0217247 0,12127527 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0217247 0,12099454 ! grooming behavior GO:0007625 6 5 0,000 0,0217247 0,1207151 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0217247 0,12043696 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0217247 0,12016009 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0217247 0,11988449 ! response to protozoan GO:0001562 10 5 0,000 0,0217247 0,11961016 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,0217247 0,11933708 ! lymph vessel development GO:0001945 10 5 0,000 0,0217247 0,11906524 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0217247 0,11879464 ! endochondral ossification GO:0001958 16 5 0,000 0,0217247 0,11852526 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0217247 0,1182571 ! parathyroid gland development GO:0060017 13 5 0,000 0,0217247 0,11799016 ! anagen GO:0042640 6 5 0,000 0,0217247 0,11772441 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0217247 0,11745986 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0217247 0,1171965 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0217247 0,11693432 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0217247 0,1166733 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0217247 0,11641345 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0217247 0,11615476 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0217247 0,11589721 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0217247 0,1156408 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0217247 0,11538552 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0217247 0,11513137 GO:0046516|hypusine metabolic process, ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0217247 0,11487833 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0217247 0,1146264 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0217247 0,11437558 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0217247 0,11412585 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0217247 0,11387721 ! histidine catabolic process GO:0006548 6 5 0,000 0,0217247 0,11362965 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0217247 0,11338317 ! microvillus organization GO:0032528 7 5 0,000 0,0217247 0,11313775 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,0217247 0,11289339 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0217247 0,11265009 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0217247 0,11240783 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0217247 0,11216661 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0217247 0,11192642 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0217247 0,11168726 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0217247 0,11144913 ! polyol catabolic process GO:0046174 7 5 0,000 0,0217247 0,111212 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0217247 0,11097588 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0217247 0,11074076 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0217247 0,11050664 ! muscle cell migration GO:0014812 8 5 0,000 0,0217247 0,1102735 ! mitochondrial fission GO:0000266 8 5 0,000 0,0217247 0,11004135 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0217247 0,10981017 ! mRNA transcription GO:0009299 9 5 0,000 0,0217247 0,10957996 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0217247 0,10935071 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0217247 0,10912242 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0217247 0,10889508 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0217247 0,10866869 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0217247 0,10844324 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0217247 0,10821872 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0217247 0,10799512 ! response to food GO:0032094 6 5 0,000 0,0217247 0,10777245 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0217247 0,1075507 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0217247 0,10732986 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0217247 0,10710992 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0217247 0,10689088 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0217247 0,10667273 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,0217247 0,10645548 ! forebrain neuron development GO:0021884 13 5 0,000 0,0217247 0,10623911 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0217247 0,10602361 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0217247 0,10580899 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0217247 0,10559523 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0217247 0,10538234 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0217247 0,1051703 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0217247 0,10495912 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0217247 0,10474878 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0217247 0,10453928 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0217247 0,10433062 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0217247 0,10412279 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0217247 0,10391578 ! basic amino acid transport GO:0015802 11 5 0,000 0,0217247 0,1037096 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0217247 0,10350424 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,0217247 0,10329968 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0217247 0,10309594 ! depyrimidination GO:0045008 10 5 0,000 0,0217247 0,10289299 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0217247 0,10269084 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0217247 0,10248949 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0217247 0,10228892 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0217247 0,10208914 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0217247 0,10189014 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0217247 0,10169191 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0217247 0,10149445 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0217247 0,10129775 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0217247 0,10110182 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0217247 0,10090664 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0217247 0,10071222 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0217247 0,10051854 ! response to arsenic GO:0046685 10 5 0,000 0,0217247 0,1003256 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0217247 0,10013341 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0217247 0,09994195 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0217247 0,09975122 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0217247 0,09956122 ! response to cadmium ion GO:0046686 7 5 0,000 0,0217247 0,09937194 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0217247 0,09918338 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0217247 0,09899553 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0217247 0,09880839 ! decidualization GO:0046697 11 5 0,000 0,0217247 0,09862196 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0217247 0,09843623 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0217247 0,0982512 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0217247 0,09806687 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0217247 0,09788322 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0217247 0,09770026 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0217247 0,09751798 ! neural tube patterning GO:0021532 7 5 0,000 0,0217247 0,09733639 ! embryonic cleavage GO:0040016 6 5 0,000 0,0217247 0,09715546 ! peroxisome fission GO:0016559 5 5 0,000 0,0217247 0,09697521 ! histone demethylation GO:0016577 10 5 0,000 0,0217247 0,09679563 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0217247 0,09661671 ! mitotic recombination GO:0006312 9 5 0,000 0,0217247 0,09643845 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0217247 0,09626085 ! metaphase plate congression GO:0051310 7 5 0,000 0,0217247 0,0960839 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0217247 0,0959076 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0217247 0,09573194 ! enteric nervous system development GO:0048484 8 5 0,000 0,0217247 0,09555693 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0217247 0,09538255 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0217247 0,09520882 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0217247 0,09503571 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0217247 0,09486323 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0217247 0,09469138 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0217247 0,09452014 ! plasminogen activation GO:0031639 5 5 0,000 0,0217247 0,09434953 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0217247 0,09417953 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0217247 0,09401014 ! metaphase GO:0051323 8 5 0,000 0,0217247 0,09384136 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0217247 0,09367319 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0217247 0,09350562 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0217247 0,09333864 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0217247 0,09317226 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0217247 0,09300648 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0217247 0,09284128 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0217247 0,09267667 ! response to redox state GO:0051775 5 5 0,000 0,0217247 0,09251264 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0217247 0,09234919 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0217247 0,09218631 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0217247 0,09202401 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0217247 0,09186228 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0217247 0,09170112 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0217247 0,09154052 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0217247 0,09138049 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0217247 0,09122101 ! striatum development GO:0021756 9 5 0,000 0,0217247 0,09106209 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0217247 0,09090372 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0217247 0,0907459 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0217247 0,09058863 ! glial cell migration GO:0008347 11 5 0,000 0,0217247 0,0904319 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0217247 0,09027572 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0217247 0,09012007 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0217247 0,08996496 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0217247 0,08981038 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0217247 0,08965633 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0217247 0,08950281 ! neuroprotection GO:0043526 6 5 0,000 0,0217247 0,08934981 ! neural plate development GO:0001840 8 5 0,000 0,0217247 0,08919734 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0217247 0,08904538 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0217247 0,08889395 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0217247 0,08874302 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0217247 0,08859261 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0217247 0,08844271 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0217247 0,08829331 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0217247 0,08814442 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0217247 0,08799603 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0217247 0,08784813 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0217247 0,08770074 ! spindle assembly GO:0051225 6 5 0,000 0,0217247 0,08755384 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0217247 0,08740742 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0217247 0,0872615 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0217247 0,08711607 ! drug metabolic process GO:0017144 6 5 0,000 0,0217247 0,08697111 ! phospholipid scrambling GO:0017121 8 5 0,000 0,0217247 0,08682664 ! organ regeneration GO:0031100 7 5 0,000 0,0217247 0,08668265 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0217247 0,08653914 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0217247 0,0863961 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0217247 0,08625353 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,0219139 0,08686134 ! synapse organization GO:0050808 85 52 1,000 0,0219139 0,08671848 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02270885 0,08971673 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,02270885 0,08956965 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,02351558 0,09259982 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02516394 0,09892881 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02516394 0,09876743 ! muscle fiber development GO:0048747 112 57 1,000 0,02600533 0,1019036 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02601311 0,10176835 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02601311 0,10160314 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02601311 0,10143847 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02601311 0,10127433 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02601311 0,10111072 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02601311 0,10094763 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02601311 0,10078508 ! sleep GO:0030431 13 6 0,000 0,02601311 0,10062304 ! response to oxygen radical GO:0000305 11 6 0,000 0,02601311 0,10046153 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02601311 0,10030053 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02601311 0,10014005 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02601311 0,09998009 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02601311 0,09982063 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02601311 0,09966168 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02601311 0,09950323 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02601311 0,09934529 ! forebrain regionalization GO:0021871 8 6 0,000 0,02601311 0,09918785 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02601311 0,09903091 ! male meiosis GO:0007140 7 6 0,000 0,02601311 0,09887446 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02601311 0,09871851 ! response to zinc ion GO:0010043 9 6 0,000 0,02601311 0,09856304 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02601311 0,09840807 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02601311 0,09825358 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02601311 0,09809958 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02601311 0,09794606 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02601311 0,09779302 ! malate metabolic process GO:0006108 11 6 0,000 0,02601311 0,09764046 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02601311 0,09748837 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02601311 0,09733675 ! protein refolding GO:0042026 15 6 0,000 0,02601311 0,09718561 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02601311 0,09703494 ! opsonization GO:0008228 8 6 0,000 0,02601311 0,09688473 ! mating behavior GO:0007617 7 6 0,000 0,02601311 0,09673498 ! neuron remodeling GO:0016322 15 6 0,000 0,02601311 0,0965857 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02601311 0,09643688 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02601311 0,09628851 ! equilibrioception GO:0050957 14 6 0,000 0,02601311 0,0961406 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02601311 0,09599315 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02601311 0,09584615 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02601311 0,09569959 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02601311 0,09555349 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02601311 0,09540783 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02601311 0,09526261 ! toxin metabolic process GO:0009404 11 6 0,000 0,02601311 0,09511783 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02601311 0,0949735 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02601311 0,0948296 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02601311 0,09468613 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02601311 0,0945431 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02601311 0,0944005 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02601311 0,09425833 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02601311 0,09411659 ! thymic T cell selection GO:0045061 12 6 0,000 0,02601311 0,09397528 ! protein lipoylation GO:0009249 10 6 0,000 0,02601311 0,09383438 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02601311 0,09369391 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02601311 0,09355386 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02601311 0,09341423 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02601311 0,09327501 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02601311 0,09313621 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02601311 0,09299782 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02601311 0,09285984 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02601311 0,09272227 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02601311 0,09258511 ! hyperosmotic response GO:0006972 9 6 0,000 0,02601311 0,09244835 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02601311 0,092312 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02601311 0,09217604 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02601311 0,09204049 ! urea metabolic process GO:0019627 7 6 0,000 0,02601311 0,09190534 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02601311 0,09177058 ! neutrophil activation GO:0042119 8 6 0,000 0,02601311 0,09163621 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02601311 0,09150224 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02601311 0,09136866 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02601311 0,09123547 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02601311 0,09110267 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02601311 0,09097025 ! nucleoside salvage GO:0043174 9 6 0,000 0,02601311 0,09083822 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02601311 0,09070657 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02601311 0,0905753 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02601311 0,09044441 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02601311 0,0903139 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02601311 0,09018377 ! carnitine transport GO:0015879 10 6 0,000 0,02601311 0,090054 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02601311 0,08992462 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02601311 0,0897956 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02601311 0,08966695 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02601311 0,08953867 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02601311 0,08941076 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02601311 0,08928321 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02601311 0,08915603 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02601311 0,08902921 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02601311 0,08890275 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02601311 0,08877664 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02601311 0,0886509 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02601311 0,08852551 ! neural nucleus development GO:0048857 14 6 0,000 0,02601311 0,08840047 ! response to UV-C GO:0010225 11 6 0,000 0,02601311 0,08827579 ! astrocyte development GO:0014002 15 6 0,000 0,02601311 0,08815146 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02601311 0,08802747 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02601311 0,08790384 ! interaction with symbiont GO:0051702 13 6 0,000 0,02601311 0,08778055 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02601311 0,08765761 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02601311 0,08753501 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02601311 0,08741276 ! response to copper ion GO:0046688 10 6 0,000 0,02601311 0,08729084 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02601311 0,08716927 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02601311 0,08704803 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02601311 0,08692713 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02601311 0,08680656 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02601311 0,08668633 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02601311 0,08656644 ! hair follicle maturation GO:0048820 7 6 0,000 0,02601311 0,08644687 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02601311 0,08632763 ! Schwann cell development GO:0014044 15 6 0,000 0,02601311 0,08620872 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02601311 0,08609014 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02601311 0,08597189 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02601311 0,08585396 ! subpallium development GO:0021544 10 6 0,000 0,02601311 0,08573635 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02601311 0,08561906 ! histone ubiquitination GO:0016574 8 6 0,000 0,02601311 0,08550209 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02601311 0,08538545 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02601311 0,08526912 ! G2 phase GO:0051319 16 6 0,000 0,02601311 0,08515311 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02601311 0,08503741 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02601311 0,08492203 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02601311 0,08480696 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02601311 0,0846922 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02601311 0,08457775 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02601311 0,08446361 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02601311 0,08434978 ! receptor internalization GO:0031623 10 6 0,000 0,02601311 0,08423625 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02601311 0,08412303 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02601311 0,08401011 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02601311 0,0838975 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02601311 0,08378519 ! protein deubiquitination GO:0016579 14 6 0,000 0,02601311 0,08367317 ! protein destabilization GO:0031648 9 6 0,000 0,02601311 0,08356146 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02601311 0,08345004 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02601311 0,08333893 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02601311 0,0832281 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02601311 0,08311757 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02601311 0,08300734 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02601311 0,08289739 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02601311 0,08278774 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02601311 0,08267838 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02601311 0,08256931 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02601311 0,08246052 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02601311 0,08235202 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02601311 0,0822438 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02601311 0,08213587 ! catecholamine transport GO:0051937 9 6 0,000 0,02601311 0,08202822 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02601311 0,08192085 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02601311 0,08181377 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02601311 0,08170696 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02601311 0,08160043 ! maternal placenta development GO:0001893 12 6 0,000 0,02601311 0,08149418 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02601311 0,08138821 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02601311 0,08128251 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02601311 0,08117709 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02601311 0,08107193 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02601311 0,08096705 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02601311 0,08086245 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02772195 0,08606325 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,02772195 0,08595234 ! establishment of organelle localization GO:0051656 109 59 1,000 0,02772195 0,08584172 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,02948296 0,09117737 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,02948296 0,09106032 ! tRNA transcription GO:0009304 14 7 0,000 0,03028285 0,09341095 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03028285 0,09329134 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03028285 0,09317204 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03028285 0,09305305 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03028285 0,09293436 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03028285 0,09281597 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03028285 0,09269789 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03028285 0,0925801 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03028285 0,09246261 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03028285 0,09234542 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03028285 0,09222853 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03028285 0,09211193 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03028285 0,09199563 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03028285 0,09187962 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03028285 0,0917639 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03028285 0,09164848 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03028285 0,09153334 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03028285 0,09141849 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03028285 0,09130393 ! glycolipid transport GO:0046836 10 7 0,000 0,03028285 0,09118966 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03028285 0,09107567 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03028285 0,09096197 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,03028285 0,09084855 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03028285 0,09073541 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03028285 0,09062256 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03028285 0,09050999 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03028285 0,09039769 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03028285 0,09028567 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03028285 0,09017393 ! mRNA stabilization GO:0048255 18 7 0,000 0,03028285 0,09006247 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03028285 0,08995128 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03028285 0,08984037 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03028285 0,08972973 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03028285 0,08961936 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03028285 0,08950926 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03028285 0,08939943 ! lipoprotein transport GO:0042953 14 7 0,000 0,03028285 0,08928987 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03028285 0,08918059 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03028285 0,08907156 ! rhythmic behavior GO:0007622 15 7 0,000 0,03028285 0,08896281 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03028285 0,08885431 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03028285 0,08874609 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03028285 0,08863812 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03028285 0,08853042 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03028285 0,08842298 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03028285 0,0883158 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03028285 0,08820888 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03028285 0,08810222 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03028285 0,08799582 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03028285 0,08788967 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03028285 0,08778378 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03028285 0,08767814 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03028285 0,08757276 ! spinal cord patterning GO:0021511 13 7 0,000 0,03028285 0,08746763 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03028285 0,08736276 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03028285 0,08725813 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03028285 0,08715375 ! adrenal gland development GO:0030325 17 7 0,000 0,03028285 0,08704963 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03028285 0,08694575 ! ovulation GO:0030728 9 7 0,000 0,03028285 0,08684212 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03028285 0,08673874 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03028285 0,0866356 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03028285 0,08653271 ! microtubule nucleation GO:0007020 20 7 0,000 0,03028285 0,08643006 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03028285 0,08632765 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03028285 0,08622549 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03028285 0,08612357 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03028285 0,08602189 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03028285 0,08592045 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03028285 0,08581924 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03028285 0,08571828 ! galactose metabolic process GO:0006012 13 7 0,000 0,03028285 0,08561755 ! vesicle fusion GO:0006906 17 7 0,000 0,03028285 0,08551706 ! response to dietary excess GO:0002021 8 7 0,000 0,03028285 0,08541681 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03028285 0,08531679 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03028285 0,085217 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03028285 0,08511745 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03028285 0,08501813 ! purine salvage GO:0043101 10 7 0,000 0,03028285 0,08491904 ! nucleoside transport GO:0015858 8 7 0,000 0,03028285 0,08482018 ! parturition GO:0007567 14 7 0,000 0,03028285 0,08472156 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03028285 0,08462316 ! rRNA modification GO:0000154 14 7 0,000 0,03028285 0,08452499 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03028285 0,08442704 ! spindle checkpoint GO:0031577 15 7 0,000 0,03028285 0,08432933 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03028285 0,08423184 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03028285 0,08413457 ! macrophage differentiation GO:0030225 11 7 0,000 0,03028285 0,08403753 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03028285 0,08394071 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03028285 0,08384412 ! fibrinolysis GO:0042730 10 7 0,000 0,03028285 0,08374774 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03028285 0,08365159 ! eating behavior GO:0042755 7 7 0,000 0,03028285 0,08355566 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03028285 0,08345995 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03028285 0,08336446 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03028285 0,08326919 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03028285 0,08317413 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03028285 0,08307929 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03028285 0,08298467 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03028285 0,08289026 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03028285 0,08279607 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03028285 0,08270209 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03028285 0,08260832 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03028285 0,08251477 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03028285 0,08242142 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03028285 0,08232829 ! regulation of meiosis GO:0040020 12 7 0,000 0,03028285 0,08223537 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03028285 0,08214266 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03028285 0,08205016 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03028285 0,08195786 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03028285 0,08186577 ! transcription termination GO:0006353 13 7 0,000 0,03028285 0,08177389 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03028285 0,08168222 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03028285 0,08159075 ! anaphase GO:0051322 17 7 0,000 0,03028285 0,08149948 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03028285 0,08140842 ! axonal fasciculation GO:0007413 18 7 0,000 0,03028285 0,08131756 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03028285 0,08122691 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03028285 0,08113646 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03028285 0,0810462 ! diuresis GO:0030146 12 7 0,000 0,03028285 0,08095615 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03028285 0,0808663 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03028285 0,08077665 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03028285 0,0806872 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03028285 0,08059794 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03028285 0,08050888 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03028285 0,08042002 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03028285 0,08033135 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03028285 0,08024288 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03028285 0,08015461 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03028285 0,08006653 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03028285 0,07997864 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03028285 0,07989094 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03028285 0,07980344 ! lymph node development GO:0048535 10 7 0,000 0,03028285 0,07971612 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03028285 0,079629 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03028285 0,07954207 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03028285 0,07945533 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03028285 0,07936878 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03028285 0,07928241 ! adult feeding behavior GO:0008343 9 7 0,000 0,03028285 0,07919624 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03028285 0,07911025 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03028285 0,07902444 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03028285 0,07893883 ! muscle adaptation GO:0043500 14 7 0,000 0,03028285 0,0788534 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03028285 0,07876815 ! retina homeostasis GO:0001895 12 7 0,000 0,03028285 0,07868309 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03028285 0,07859821 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03028285 0,07851351 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03028285 0,078429 ! protein prenylation GO:0018342 18 7 0,000 0,03028285 0,07834466 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03028285 0,07826051 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03028285 0,07817654 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03028285 0,07809275 ! ear development GO:0043583 103 62 1,000 0,03037982 0,07825893 ! gonad development GO:0008406 98 62 1,000 0,03037982 0,07817523 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,03037982 0,07809171 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,03128744 0,08033894 ! detection of external stimulus GO:0009581 91 63 1,000 0,03128744 0,08025329 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,03128744 0,08016782 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,03220572 0,08243293 ! germ cell development GO:0007281 118 65 1,000 0,03313453 0,08472017 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,03313453 0,08463023 ! actin filament organization GO:0007015 148 66 1,000 0,03407378 0,08693691 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03453402 0,08801785 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03453402 0,08792471 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,03453402 0,08783176 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03453402 0,08773902 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03453402 0,08764646 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03453402 0,08755411 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03453402 0,08746195 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03453402 0,08736998 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03453402 0,0872782 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03453402 0,08718662 ! meiotic prophase I GO:0007128 13 8 0,000 0,03453402 0,08709523 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03453402 0,08700403 ! oligopeptide transport GO:0006857 15 8 0,000 0,03453402 0,08691302 ! UTP metabolic process GO:0046051 8 8 0,000 0,03453402 0,0868222 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03453402 0,08673157 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03453402 0,08664113 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03453402 0,08655088 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03453402 0,08646082 ! succinate metabolic process GO:0006105 14 8 0,000 0,03453402 0,08637094 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03453402 0,08628125 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03453402 0,08619175 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03453402 0,08610243 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03453402 0,0860133 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03453402 0,08592435 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03453402 0,08583559 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03453402 0,085747 ! reflex GO:0060004 16 8 0,000 0,03453402 0,08565861 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03453402 0,08557039 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03453402 0,08548235 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03453402 0,0853945 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03453402 0,08530683 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03453402 0,08521933 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03453402 0,08513202 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03453402 0,08504488 ! pigment granule organization GO:0048753 16 8 0,000 0,03453402 0,08495792 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03453402 0,08487114 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03453402 0,08478454 ! histidine metabolic process GO:0006547 16 8 0,000 0,03453402 0,08469811 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03453402 0,08461186 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03453402 0,08452579 ! glycine catabolic process GO:0006546 13 8 0,000 0,03453402 0,08443989 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03453402 0,08435416 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03453402 0,08426861 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03453402 0,08418323 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03453402 0,08409802 ! melanin metabolic process GO:0006582 15 8 0,000 0,03453402 0,08401299 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03453402 0,08392813 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03453402 0,08384344 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03453402 0,08375892 ! macrophage activation GO:0042116 12 8 0,000 0,03453402 0,08367457 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03453402 0,08359039 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03453402 0,08350638 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03453402 0,08342254 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03453402 0,08333886 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03453402 0,08325536 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03453402 0,08317202 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03453402 0,08308885 ! osteoblast development GO:0002076 16 8 0,000 0,03453402 0,08300584 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03453402 0,082923 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03453402 0,08284033 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03453402 0,08275782 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03453402 0,08267547 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03453402 0,08259329 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03453402 0,08251127 ! response to UV-B GO:0010224 16 8 0,000 0,03453402 0,08242941 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03453402 0,08234772 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03453402 0,08226619 ! intermediate filament organization GO:0045109 12 8 0,000 0,03453402 0,08218481 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03453402 0,0821036 ! cellular extravasation GO:0045123 12 8 0,000 0,03453402 0,08202255 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03453402 0,08194166 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03453402 0,08186093 ! response to antibiotic GO:0046677 11 8 0,000 0,03453402 0,08178036 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03453402 0,08169995 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03453402 0,08161969 ! DNA topological change GO:0006265 12 8 0,000 0,03453402 0,0815396 ! response to tropane GO:0014073 15 8 0,000 0,03453402 0,08145965 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03453402 0,08137987 ! melanosome transport GO:0032402 13 8 0,000 0,03453402 0,08130024 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03453402 0,08122077 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03453402 0,08114145 ! mast cell activation GO:0045576 14 8 0,000 0,03453402 0,08106229 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03453402 0,08098328 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03453402 0,08090443 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03453402 0,08082573 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03453402 0,08074718 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03453402 0,08066878 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03453402 0,08059054 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03453402 0,08051245 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03453402 0,08043451 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03453402 0,08035672 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03453402 0,08027908 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03453402 0,08020159 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03453402 0,08012425 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03453402 0,08004706 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03453402 0,07997002 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03453402 0,07989312 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03453402 0,07981638 ! hormone catabolic process GO:0042447 17 8 0,000 0,03453402 0,07973978 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03453402 0,07966332 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03453402 0,07958702 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03453402 0,07951086 ! ATP catabolic process GO:0006200 11 8 0,000 0,03453402 0,07943484 ! blastocyst growth GO:0001832 19 8 0,000 0,03453402 0,07935898 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03453402 0,07928325 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03453402 0,07920767 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03453402 0,07913224 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03453402 0,07905694 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03453402 0,07898179 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03453402 0,07890679 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03453402 0,07883192 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03453402 0,0787572 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03453402 0,07868262 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03453402 0,07860818 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03453402 0,07853388 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03453402 0,07845972 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03453402 0,07838571 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03453402 0,07831183 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03453402 0,07823809 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03453402 0,07816449 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,03502335 0,07919753 ! lung development GO:0030324 144 67 1,000 0,03502335 0,07912316 ! chromosome segregation GO:0007059 113 67 1,000 0,03502335 0,07904894 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,03502335 0,07897485 ! adaptive immune response GO:0002250 119 67 1,000 0,03502335 0,07890091 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,03598313 0,08098729 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,03598313 0,0809116 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,03598313 0,08083606 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,03695303 0,08293749 ! respiratory tube development GO:0030323 150 70 1,000 0,03793293 0,08505745 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03876669 0,08684605 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03876669 0,08676526 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03876669 0,08668462 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03876669 0,08660414 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03876669 0,0865238 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03876669 0,08644361 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03876669 0,08636357 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03876669 0,08628368 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03876669 0,08620393 ! phosphate transport GO:0006817 19 9 0,000 0,03876669 0,08612434 ! reproductive behavior GO:0019098 19 9 0,000 0,03876669 0,08604489 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03876669 0,08596558 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03876669 0,08588642 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03876669 0,08580741 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03876669 0,08572854 ! GTP metabolic process GO:0046039 9 9 0,000 0,03876669 0,08564982 ! RNA methylation GO:0001510 15 9 0,000 0,03876669 0,08557124 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03876669 0,08549281 ! artery development GO:0060840 24 9 0,000 0,03876669 0,08541452 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03876669 0,08533637 ! regulation of glycolysis GO:0006110 21 9 0,000 0,03876669 0,08525837 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03876669 0,08518051 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03876669 0,08510279 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03876669 0,08502521 ! chemosensory behavior GO:0007635 20 9 0,000 0,03876669 0,08494777 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03876669 0,08487048 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03876669 0,08479332 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03876669 0,08471631 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03876669 0,08463943 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03876669 0,0845627 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03876669 0,0844861 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03876669 0,08440964 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03876669 0,08433332 ! protein targeting to ER GO:0045047 22 9 0,000 0,03876669 0,08425714 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03876669 0,0841811 ! T cell selection GO:0045058 23 9 0,000 0,03876669 0,08410519 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,03876669 0,08402942 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03876669 0,08395379 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03876669 0,08387829 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03876669 0,08380293 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03876669 0,0837277 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03876669 0,08365261 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03876669 0,08357765 ! mannose metabolic process GO:0006013 13 9 0,000 0,03876669 0,08350283 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03876669 0,08342814 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03876669 0,08335358 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03876669 0,08327916 ! receptor clustering GO:0043113 18 9 0,000 0,03876669 0,08320487 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03876669 0,08313071 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03876669 0,08305668 ! ruffle organization GO:0031529 15 9 0,000 0,03876669 0,08298279 ! retinol metabolic process GO:0042572 18 9 0,000 0,03876669 0,08290903 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03876669 0,0828354 ! behavioral fear response GO:0001662 22 9 0,000 0,03876669 0,0827619 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03876669 0,08268852 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03876669 0,08261528 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03876669 0,08254217 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,03876669 0,08246919 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03876669 0,08239634 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03876669 0,08232361 ! segment specification GO:0007379 13 9 0,000 0,03876669 0,08225102 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03876669 0,08217855 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03876669 0,08210621 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03876669 0,082034 ! response to amine stimulus GO:0014075 13 9 0,000 0,03876669 0,08196191 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03876669 0,08188995 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03876669 0,08181812 ! erythrocyte development GO:0048821 15 9 0,000 0,03876669 0,08174641 ! gas homeostasis GO:0033483 16 9 0,000 0,03876669 0,08167483 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03876669 0,08160337 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03876669 0,08153204 ! renal water homeostasis GO:0003091 14 9 0,000 0,03876669 0,08146083 ! postreplication repair GO:0006301 22 9 0,000 0,03876669 0,08138975 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03876669 0,08131879 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03876669 0,08124796 ! icosanoid secretion GO:0032309 15 9 0,000 0,03876669 0,08117725 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03876669 0,08110666 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03876669 0,08103619 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03876669 0,08096585 ! regulation of cell division GO:0051302 15 9 0,000 0,03876669 0,08089563 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03876669 0,08082552 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03876669 0,08075555 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03876669 0,08068569 ! sterol catabolic process GO:0016127 11 9 0,000 0,03876669 0,08061595 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03876669 0,08054633 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03876669 0,08047684 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03876669 0,08040746 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03876669 0,0803382 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03876669 0,08026907 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03876669 0,08020005 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03876669 0,08013115 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03876669 0,08006237 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03876669 0,0799937 ! purine base metabolic process GO:0006144 21 9 0,000 0,03876669 0,07992515 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03876669 0,07985673 ! pigment granule transport GO:0051904 17 9 0,000 0,03876669 0,07978841 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03876669 0,07972022 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03876669 0,07965214 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03876669 0,07958418 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03876669 0,07951633 ! mitochondrion localization GO:0051646 15 9 0,000 0,03876669 0,0794486 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,03892274 0,07970052 ! carbohydrate transport GO:0008643 110 72 1,000 0,03992234 0,08167785 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,03992234 0,08160845 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,03992234 0,08153917 ! respiratory system development GO:0060541 153 72 1,000 0,03992234 0,08147001 ! regulation of blood pressure GO:0008217 125 73 1,000 0,04093163 0,0834589 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,04195051 0,08546396 ! organelle localization GO:0051640 136 74 1,000 0,04195051 0,08539166 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,04297889 0,08741099 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,04297889 0,08733716 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,04297889 0,08726346 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04298095 0,08719406 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04298095 0,0871206 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04298095 0,08704727 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04298095 0,08697406 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04298095 0,08690097 ! synapsis GO:0007129 13 10 0,000 0,04298095 0,086828 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04298095 0,08675516 ! N-glycan processing GO:0006491 20 10 0,000 0,04298095 0,08668244 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04298095 0,08660984 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04298095 0,08653737 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04298095 0,08646501 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04298095 0,08639278 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04298095 0,08632066 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04298095 0,08624867 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04298095 0,08617679 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04298095 0,08610504 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04298095 0,08603341 ! androgen metabolic process GO:0008209 17 10 0,000 0,04298095 0,08596189 ! phospholipid efflux GO:0033700 16 10 0,000 0,04298095 0,08589049 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04298095 0,08581921 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04298095 0,08574805 ! lung alveolus development GO:0048286 26 10 0,000 0,04298095 0,08567701 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04298095 0,08560609 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04298095 0,08553528 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04298095 0,08546459 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04298095 0,08539402 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04298095 0,08532356 ! endoderm development GO:0007492 16 10 0,000 0,04298095 0,08525322 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04298095 0,08518299 ! arginine catabolic process GO:0006527 13 10 0,000 0,04298095 0,08511288 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04298095 0,08504289 ! proline metabolic process GO:0006560 13 10 0,000 0,04298095 0,08497301 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04298095 0,08490325 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04298095 0,0848336 ! V(D)J recombination GO:0033151 28 10 0,000 0,04298095 0,08476406 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04298095 0,08469464 ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04298095 0,08462533 ! B cell proliferation GO:0042100 18 10 0,000 0,04298095 0,08455614 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04298095 0,08448705 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04298095 0,08441808 ! multicellular organism growth GO:0035264 18 10 0,000 0,04298095 0,08434923 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04298095 0,08428048 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04298095 0,08421185 ! epithelial cell development GO:0002064 20 10 0,000 0,04298095 0,08414333 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04298095 0,08407492 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04298095 0,08400662 ! macroautophagy GO:0016236 17 10 0,000 0,04298095 0,08393844 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04298095 0,08387036 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04298095 0,08380239 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04298095 0,08373454 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04298095 0,08366679 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04298095 0,08359915 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04298095 0,08353163 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04298095 0,08346421 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04298095 0,0833969 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04298095 0,0833297 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04298095 0,0832626 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04298095 0,08319562 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04298095 0,08312874 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04298095 0,08306197 ! response to dsRNA GO:0043331 20 10 0,000 0,04298095 0,08299531 ! DNA ligation GO:0006266 19 10 0,000 0,04298095 0,08292875 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04298095 0,0828623 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04298095 0,08279596 ! melanosome localization GO:0032400 16 10 0,000 0,04298095 0,08272972 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04298095 0,08266359 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04298095 0,08259757 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04298095 0,08253165 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04298095 0,08246583 ! mRNA cleavage GO:0006379 17 10 0,000 0,04298095 0,08240012 ! protein sumoylation GO:0016925 15 10 0,000 0,04298095 0,08233452 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04298095 0,08226902 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04298095 0,08220362 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04298095 0,08213833 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04298095 0,08207314 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04298095 0,08200805 ! salivary gland development GO:0007431 27 10 0,000 0,04298095 0,08194307 ! prophase GO:0051324 15 10 0,000 0,04298095 0,08187819 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04298095 0,08181341 ! apical protein localization GO:0045176 15 10 0,000 0,04298095 0,08174874 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04298095 0,08168417 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04298095 0,0816197 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04298095 0,08155533 ! midbrain development GO:0030901 13 10 0,000 0,04298095 0,08149106 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04298095 0,08142689 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04298095 0,08136283 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04298095 0,08129886 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04298095 0,081235 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04298095 0,08117124 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04298095 0,08110757 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04298095 0,08104401 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04298095 0,08098054 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04298095 0,08091718 ! oocyte development GO:0048599 17 10 0,000 0,04298095 0,08085391 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04298095 0,08079075 ! blastocyst formation GO:0001825 17 10 0,000 0,04298095 0,08072768 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04298095 0,08066471 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04298095 0,08060183 ! activation of innate immune response GO:0002218 12 10 0,000 0,04298095 0,08053906 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04298095 0,08047638 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04298095 0,08041381 ! response to nicotine GO:0035094 20 10 0,000 0,04298095 0,08035132 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04298095 0,08028894 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04298095 0,08022665 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04298095 0,08016446 ! localization within membrane GO:0051668 20 10 0,000 0,04298095 0,08010237 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,04506369 0,08391891 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,04611992 0,08581943 ! protein oligomerization GO:0051259 139 78 1,000 0,04611992 0,08575311 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04717686 0,08765061 ! respiratory burst GO:0045730 17 11 0,000 0,04717686 0,08758297 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04717686 0,08751545 ! neuron fate specification GO:0048665 17 11 0,000 0,04717686 0,08744802 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04717686 0,0873807 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04717686 0,08731349 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04717686 0,08724637 ! thyroid gland development GO:0030878 26 11 0,000 0,04717686 0,08717937 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,04717686 0,08711246 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04717686 0,08704565 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04717686 0,08697895 ! response to pain GO:0048265 24 11 0,000 0,04717686 0,08691235 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04717686 0,08684586 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04717686 0,08677946 ! bone resorption GO:0045453 16 11 0,000 0,04717686 0,08671317 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,04717686 0,08664697 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04717686 0,08658088 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04717686 0,08651489 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04717686 0,086449 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04717686 0,08638321 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04717686 0,08631752 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04717686 0,08625193 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04717686 0,08618643 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04717686 0,08612104 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04717686 0,08605575 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,04717686 0,08599056 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04717686 0,08592546 ! UV protection GO:0009650 19 11 0,000 0,04717686 0,08586046 ! adult heart development GO:0007512 14 11 0,000 0,04717686 0,08579557 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04717686 0,08573077 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04717686 0,08566606 ! temperature homeostasis GO:0001659 17 11 0,000 0,04717686 0,08560146 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04717686 0,08553695 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04717686 0,08547254 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04717686 0,08540823 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04717686 0,08534401 ! regulation of organ growth GO:0046620 13 11 0,000 0,04717686 0,08527989 ! pigment granule localization GO:0051875 20 11 0,000 0,04717686 0,08521587 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04717686 0,08515194 ! vasoconstriction GO:0042310 18 11 0,000 0,04717686 0,08508811 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04717686 0,08502437 ! embryonic axis specification GO:0000578 18 11 0,000 0,04717686 0,08496073 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04717686 0,08489718 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04717686 0,08483373 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04717686 0,08477038 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04717686 0,08470711 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04717686 0,08464395 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04717686 0,08458087 ! zymogen activation GO:0031638 15 11 0,000 0,04717686 0,0845179 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04717686 0,08445501 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04717686 0,08439222 ! nucleosome positioning GO:0016584 15 11 0,000 0,04717686 0,08432952 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04717686 0,08426691 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04717686 0,0842044 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04717686 0,08414198 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04717686 0,08407965 ! acid secretion GO:0046717 18 11 0,000 0,04717686 0,08401742 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04717686 0,08395528 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04717686 0,08389323 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04717686 0,08383127 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04717686 0,0837694 ! oocyte differentiation GO:0009994 18 11 0,000 0,04717686 0,08370762 ! thymus development GO:0048538 27 11 0,000 0,04717686 0,08364593 ! cholesterol efflux GO:0033344 19 11 0,000 0,04717686 0,08358434 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04717686 0,08352284 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04717686 0,08346142 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04717686 0,0834001 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04717686 0,08333886 ! embryonic gut development GO:0048566 15 11 0,000 0,04717686 0,08327772 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04717686 0,08321667 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04717686 0,0831557 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04717686 0,08309483 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04717686 0,08303404 ! defense response to fungus GO:0050832 13 11 0,000 0,04717686 0,08297334 ! developmental induction GO:0031128 19 11 0,000 0,04717686 0,08291273 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04717686 0,08285221 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04717686 0,08279178 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04717686 0,08273144 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04717686 0,08267118 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04717686 0,08261101 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04717686 0,08255093 ! nucleus localization GO:0051647 19 11 0,000 0,04717686 0,08249094 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04717686 0,08243103 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,04718524 0,08238583 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,04718524 0,08232609 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,04934274 0,08602799 ! response to drug GO:0042493 143 82 1,000 0,05043472 0,08786817 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05135452 0,08940592 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05135452 0,08934128 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05135452 0,08927672 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05135452 0,08921226 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05135452 0,0891479 ! virus-host interaction GO:0019048 29 12 0,000 0,05135452 0,08908362 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05135452 0,08901944 ! cartilage condensation GO:0001502 20 12 0,000 0,05135452 0,08895535 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05135452 0,08889136 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05135452 0,08882745 ! protein complex disassembly GO:0043241 27 12 0,000 0,05135452 0,08876364 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05135452 0,08869992 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05135452 0,08863629 ! hippocampus development GO:0021766 26 12 0,000 0,05135452 0,08857275 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,05135452 0,0885093 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05135452 0,08844595 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05135452 0,08838268 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05135452 0,0883195 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05135452 0,08825642 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05135452 0,08819342 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05135452 0,08813052 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05135452 0,0880677 ! drug transport GO:0015893 16 12 0,000 0,05135452 0,08800498 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05135452 0,08794234 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05135452 0,08787979 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05135452 0,08781733 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05135452 0,08775496 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05135452 0,08769268 ! forebrain cell migration GO:0021885 21 12 0,000 0,05135452 0,08763049 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05135452 0,08756838 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05135452 0,08750636 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05135452 0,08744443 ! entry into host cell GO:0030260 32 12 0,000 0,05135452 0,08738259 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05135452 0,08732084 ! monoamine transport GO:0015844 18 12 0,000 0,05135452 0,08725917 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05135452 0,08719759 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05135452 0,0871361 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05135452 0,08707469 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05135452 0,08701337 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05135452 0,08695214 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05135452 0,08689099 ! protein homotetramerization GO:0051289 21 12 0,000 0,05135452 0,08682993 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05135452 0,08676895 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05135452 0,08670806 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05135452 0,08664725 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05135452 0,08658653 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05135452 0,0865259 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05135452 0,08646535 ! cranial nerve development GO:0021545 20 12 0,000 0,05135452 0,08640488 ! fucose catabolic process GO:0019317 22 12 0,000 0,05135452 0,0863445 GO:0042355|L-fucose catabolic process, ! histone acetylation GO:0016573 26 12 0,000 0,05135452 0,08628421 ! histone methylation GO:0016571 26 12 0,000 0,05135452 0,086224 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05135452 0,08616387 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05135452 0,08610382 ! gland morphogenesis GO:0022612 29 12 0,000 0,05135452 0,08604386 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05135452 0,08598398 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05135452 0,08592419 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05135452 0,08586448 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05135452 0,08580485 ! spleen development GO:0048536 22 12 0,000 0,05135452 0,08574531 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05135452 0,08568584 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05135452 0,08562646 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05135452 0,08556716 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05135452 0,08550795 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05135452 0,08544881 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05135452 0,08538976 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05135452 0,08533079 ! response to cold GO:0009409 17 12 0,000 0,05135452 0,0852719 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05135452 0,08521309 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05135452 0,08515437 ! amine biosynthetic process GO:0009309 138 86 1,000 0,05488869 0,09095192 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05551401 0,09192478 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05551401 0,09186155 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05551401 0,09179842 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05551401 0,09173537 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05551401 0,09167241 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05551401 0,09160953 ! lipid localization GO:0010876 28 13 0,000 0,05551401 0,09154674 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05551401 0,09148404 ! organelle fusion GO:0048284 32 13 0,000 0,05551401 0,09142142 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05551401 0,09135889 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05551401 0,09129644 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05551401 0,09123408 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05551401 0,09117181 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05551401 0,09110962 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05551401 0,09104751 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05551401 0,09098549 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05551401 0,09092355 ! methionine metabolic process GO:0006555 27 13 0,000 0,05551401 0,0908617 ! plasma membrane organization GO:0007009 24 13 0,000 0,05551401 0,09079993 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05551401 0,09073825 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05551401 0,09067665 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05551401 0,09061513 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05551401 0,09055369 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05551401 0,09049234 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05551401 0,09043108 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05551401 0,09036989 ! exocrine system development GO:0035272 32 13 0,000 0,05551401 0,09030879 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05551401 0,09024777 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05551401 0,09018683 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05551401 0,09012598 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05551401 0,0900652 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05551401 0,09000451 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05551401 0,0899439 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05551401 0,08988338 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05551401 0,08982293 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05551401 0,08976257 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05551401 0,08970228 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05551401 0,08964208 ! ribosome assembly GO:0042255 17 13 0,000 0,05551401 0,08958196 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,05551401 0,08952192 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05551401 0,08946195 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05551401 0,08940207 ! chromatin silencing GO:0006342 26 13 0,000 0,05551401 0,08934227 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05551401 0,08928255 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05551401 0,08922291 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05551401 0,08916335 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05551401 0,08910387 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05551401 0,08904447 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05551401 0,08898514 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05551401 0,0889259 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05551401 0,08886673 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05551401 0,08880765 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05551401 0,08874864 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05551401 0,08868971 ! embryonic placenta development GO:0001892 23 13 0,000 0,05551401 0,08863086 ! insulin secretion GO:0030073 23 13 0,000 0,05551401 0,08857208 ! actin filament polymerization GO:0030041 24 13 0,000 0,05551401 0,08851339 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05551401 0,08845477 ! acrosome reaction GO:0007340 18 13 0,000 0,05551401 0,08839623 ! rRNA transcription GO:0009303 25 14 0,000 0,05965539 0,09492782 ! lactation GO:0007595 26 14 0,000 0,05965539 0,09486508 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,05965539 0,09480242 ! reproductive cellular process GO:0048610 20 14 0,000 0,05965539 0,09473984 ! tRNA modification GO:0006400 20 14 0,000 0,05965539 0,09467735 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05965539 0,09461494 ! regulation of S phase GO:0033261 23 14 0,000 0,05965539 0,09455261 ! water transport GO:0006833 21 14 0,000 0,05965539 0,09449036 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05965539 0,0944282 ! non-recombinational repair GO:0000726 25 14 0,000 0,05965539 0,09436612 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05965539 0,09430411 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05965539 0,09424219 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05965539 0,09418036 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05965539 0,0941186 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05965539 0,09405692 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05965539 0,09399533 ! palate development GO:0060021 31 14 0,000 0,05965539 0,09393381 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05965539 0,09387238 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05965539 0,09381102 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05965539 0,09374975 ! arginine metabolic process GO:0006525 17 14 0,000 0,05965539 0,09368855 ! regulation of heart rate GO:0002027 24 14 0,000 0,05965539 0,09362744 ! organic alcohol transport GO:0015850 29 14 0,000 0,05965539 0,0935664 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05965539 0,09350545 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05965539 0,09344457 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05965539 0,09338378 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05965539 0,09332306 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05965539 0,09326242 ! L-amino acid transport GO:0015807 30 14 0,000 0,05965539 0,09320186 ! bone mineralization GO:0030282 17 14 0,000 0,05965539 0,09314138 ! stem cell development GO:0048864 43 14 0,000 0,05965539 0,09308097 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05965539 0,09302065 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05965539 0,0929604 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05965539 0,09290023 ! cerebellum development GO:0021549 21 14 0,000 0,05965539 0,09284014 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05965539 0,09278013 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05965539 0,0927202 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05965539 0,09266034 ! cofactor transport GO:0051181 26 14 0,000 0,05965539 0,09260056 ! NADP metabolic process GO:0006739 24 14 0,000 0,05965539 0,09254085 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,05965539 0,09248123 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05965539 0,09242168 ! intestinal absorption GO:0050892 25 14 0,000 0,05965539 0,0923622 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05965539 0,09230281 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05965539 0,09224349 ! regulation of RNA stability GO:0043487 32 14 0,000 0,05965539 0,09218424 ! regulation of axon extension GO:0030516 37 14 0,000 0,05965539 0,09212507 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05965539 0,09206598 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,0629998 0,09716508 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 164 93 1,000 0,0629998 0,09710283 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06377875 0,0982405 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06377875 0,09817765 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06377875 0,09811488 ! superoxide anion generation GO:0042554 20 15 0,000 0,06377875 0,09805218 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06377875 0,09798957 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06377875 0,09792704 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06377875 0,09786458 ! copper ion transport GO:0006825 20 15 0,000 0,06377875 0,09780221 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06377875 0,09773991 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06377875 0,0976777 ! sulfate transport GO:0008272 23 15 0,000 0,06377875 0,09761556 ! response to cAMP GO:0051591 22 15 0,000 0,06377875 0,09755351 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06377875 0,09749153 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06377875 0,09742963 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06377875 0,09736781 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06377875 0,09730607 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06377875 0,0972444 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06377875 0,09718282 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06377875 0,09712131 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06377875 0,09705988 ! pituitary gland development GO:0021983 29 15 0,000 0,06377875 0,09699852 ! vesicle coating GO:0006901 33 15 0,000 0,06377875 0,09693725 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06377875 0,09687605 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06377875 0,09681493 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06377875 0,09675389 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06377875 0,09669292 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06377875 0,09663203 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06377875 0,09657122 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06377875 0,09651048 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06377875 0,09644982 ! histone deacetylation GO:0016575 20 15 0,000 0,06377875 0,09638924 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06377875 0,09632873 ! tissue regeneration GO:0042246 26 15 0,000 0,06377875 0,0962683 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06377875 0,09620794 ! water homeostasis GO:0030104 27 15 0,000 0,06377875 0,09614766 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06377875 0,09608745 ! muscle maintenance GO:0046716 26 15 0,000 0,06377875 0,09602733 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06377875 0,09596727 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06377875 0,09590729 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06377875 0,09584739 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06377875 0,09578756 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06377875 0,0957278 ! cell killing GO:0001906 29 15 0,000 0,06377875 0,09566812 ! detection of bacterium GO:0016045 18 15 0,000 0,06377875 0,09560851 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06377875 0,09554898 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06377875 0,09548952 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06377875 0,09543014 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06377875 0,09537083 ! peptide hormone processing GO:0016486 23 15 0,000 0,06377875 0,09531159 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,06418996 0,09586657 ! transcription initiation GO:0006352 153 94 1,000 0,06418996 0,0958071 ! leukocyte differentiation GO:0002521 202 96 1,000 0,06659296 0,0993321 ! detection of stimulus GO:0051606 151 96 1,000 0,06659296 0,09927055 ! protein ubiquitination GO:0016567 217 97 1,000 0,06780563 0,10101569 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06788416 0,10107011 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06788416 0,1010076 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06788416 0,10094518 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06788416 0,10088283 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06788416 0,10082055 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06788416 0,10075836 ! bone remodeling GO:0046849 27 16 0,000 0,06788416 0,10069624 ! filopodium assembly GO:0046847 32 16 0,000 0,06788416 0,10063419 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06788416 0,10057223 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06788416 0,10051033 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06788416 0,10044852 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06788416 0,10038678 ! startle response GO:0001964 28 16 0,000 0,06788416 0,10032512 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06788416 0,10026353 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06788416 0,10020202 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06788416 0,10014059 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06788416 0,10007922 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06788416 0,10001794 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06788416 0,09995673 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06788416 0,09989559 ! response to osmotic stress GO:0006970 25 16 0,000 0,06788416 0,09983453 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06788416 0,09977355 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06788416 0,09971263 ! fructose metabolic process GO:0006000 25 16 0,000 0,06788416 0,0996518 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06788416 0,09959103 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06788416 0,09953034 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06788416 0,09946973 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06788416 0,09940919 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06788416 0,09934872 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06788416 0,09928832 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06788416 0,099228 ! DNA replication initiation GO:0006270 27 16 0,000 0,06788416 0,09916776 ! neuron recognition GO:0008038 35 16 0,000 0,06788416 0,09910758 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06788416 0,09904748 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06788416 0,09898745 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06788416 0,0989275 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06788416 0,09886761 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06788416 0,0988078 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06788416 0,09874806 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06788416 0,0986884 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06788416 0,0986288 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06788416 0,09856928 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06788416 0,09850983 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06788416 0,09845045 ! defense response to virus GO:0051607 37 16 0,000 0,06788416 0,09839114 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,07025285 0,101763 GO:0060538|skeletal muscle organ development, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07197171 0,10419009 ! metencephalon development GO:0022037 30 17 0,000 0,07197171 0,10412744 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07197171 0,10406487 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07197171 0,10400236 ! signal complex assembly GO:0007172 41 17 0,000 0,07197171 0,10393994 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07197171 0,10387759 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07197171 0,10381531 ! glial cell development GO:0021782 27 17 0,000 0,07197171 0,10375311 ! limbic system development GO:0021761 36 17 0,000 0,07197171 0,10369098 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07197171 0,10362893 ! adult walking behavior GO:0007628 33 17 0,000 0,07197171 0,10356695 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07197171 0,10350504 ! heart looping GO:0001947 30 17 0,000 0,07197171 0,10344321 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07197171 0,10338145 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07197171 0,10331977 ! myoblast differentiation GO:0045445 45 17 0,000 0,07197171 0,10325816 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07197171 0,10319662 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07197171 0,10313516 ! glycine metabolic process GO:0006544 28 17 0,000 0,07197171 0,10307377 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07197171 0,10301245 ! NAD metabolic process GO:0019674 29 17 0,000 0,07197171 0,10295121 ! membrane budding GO:0006900 37 17 0,000 0,07197171 0,10289004 ! DNA integration GO:0015074 29 17 0,000 0,07197171 0,10282894 ! regulation of protein binding GO:0043393 33 17 0,000 0,07197171 0,10276791 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07197171 0,10270696 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07197171 0,10264608 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07197171 0,10258527 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07197171 0,10252453 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07197171 0,10246387 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07197171 0,10240327 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07197171 0,10234275 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07197171 0,1022823 ! steroid catabolic process GO:0006706 31 17 0,000 0,07197171 0,10222192 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07197171 0,10216161 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07197171 0,10210138 ! organic cation transport GO:0015695 31 17 0,000 0,07197171 0,10204121 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07197171 0,10198112 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07197171 0,10192109 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07197171 0,10186114 ! microspike assembly GO:0030035 36 17 0,000 0,07197171 0,10180126 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07197171 0,10174144 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07197171 0,1016817 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07604147 0,10736841 ! neuron maturation GO:0042551 42 18 0,000 0,07604147 0,10730544 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07604147 0,10724254 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,07604147 0,10717972 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,07604147 0,10711696 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07604147 0,10705429 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07604147 0,10699168 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07604147 0,10692915 ! memory GO:0007613 31 18 0,000 0,07604147 0,10686669 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07604147 0,10680431 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07604147 0,10674199 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07604147 0,10667975 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07604147 0,10661758 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07604147 0,10655549 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,07604147 0,10649347 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07604147 0,10643152 ! response to retinoic acid GO:0032526 26 18 0,000 0,07604147 0,10636964 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,07604147 0,10630783 ! response to fungus GO:0009620 21 18 0,000 0,07604147 0,10624609 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07604147 0,10618443 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07604147 0,10612284 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07604147 0,10606132 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07604147 0,10599987 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07604147 0,10593849 ! vitamin transport GO:0051180 27 18 0,000 0,07604147 0,10587718 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07604147 0,10581595 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07604147 0,10575478 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,07604147 0,10569369 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,07604147 0,10563266 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07604147 0,10557171 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07604147 0,10551083 ! nerve development GO:0021675 28 18 0,000 0,07604147 0,10545001 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07604147 0,10538927 ! protein secretion GO:0009306 39 19 0,000 0,08009351 0,11094128 ! positive regulation of translation GO:0045727 30 19 0,000 0,08009351 0,11087744 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08009351 0,11081368 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08009351 0,11075 ! skin development GO:0043588 36 19 0,000 0,08009351 0,11068639 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08009351 0,11062285 ! lipid phosphorylation GO:0046834 35 19 0,000 0,08009351 0,11055938 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08009351 0,11049598 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,08009351 0,11043266 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08009351 0,11036941 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08009351 0,11030624 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08009351 0,11024313 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,08009351 0,1101801 ! cerebral cortex development GO:0021987 36 19 0,000 0,08009351 0,11011714 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,08009351 0,11005425 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,08009351 0,10999144 ! heme metabolic process GO:0042168 36 19 0,000 0,08009351 0,10992869 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08009351 0,10986602 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08009351 0,10980342 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,08009351 0,10974089 ! peptide cross-linking GO:0018149 37 19 0,000 0,08009351 0,10967843 ! protein export from nucleus GO:0006611 36 19 0,000 0,08009351 0,10961604 ! heart process GO:0003015 30 19 0,000 0,08009351 0,10955372 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08009351 0,10949148 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08009351 0,1094293 ! visual learning GO:0008542 36 19 0,000 0,08009351 0,10936719 ! cellular pigmentation GO:0033059 36 19 0,000 0,08009351 0,10930516 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08009351 0,1092432 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08009351 0,1091813 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08009351 0,10911948 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08009351 0,10905772 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,08009351 0,10899604 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08009351 0,10893442 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08009351 0,10887288 ! cilium assembly GO:0042384 37 19 0,000 0,08009351 0,1088114 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08009351 0,10875 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08412792 0,11416344 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08412792 0,11409909 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08412792 0,11403481 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08412792 0,1139706 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08412792 0,11390646 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,08412792 0,1138424 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,08412792 0,11377841 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08412792 0,11371449 ! response to vitamin GO:0033273 31 20 0,000 0,08412792 0,11365064 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08412792 0,11358686 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08412792 0,11352316 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08412792 0,11345952 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08412792 0,11339596 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08412792 0,11333247 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,08412792 0,11326905 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08412792 0,1132057 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08412792 0,11314242 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08412792 0,11307921 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08412792 0,11301607 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08412792 0,11295301 ! body fluid secretion GO:0007589 31 20 0,000 0,08412792 0,11289001 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08412792 0,11282708 ! peptide secretion GO:0002790 35 20 0,000 0,08412792 0,11276423 ! stem cell differentiation GO:0048863 53 20 0,000 0,08412792 0,11270144 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08412792 0,11263872 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08412792 0,11257608 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08412792 0,1125135 ! sensory perception of pain GO:0019233 30 20 0,000 0,08412792 0,11245099 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08412792 0,11238855 ! diencephalon development GO:0021536 34 20 0,000 0,08412792 0,11232619 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08412792 0,11226389 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08412792 0,11220166 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08412792 0,11213949 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,08412792 0,1120774 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08412792 0,11201538 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08412792 0,11195342 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08412792 0,11189153 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08412792 0,11182972 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08412792 0,11176797 ! regulation of glucose import GO:0046324 29 20 0,000 0,08412792 0,11170628 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08412792 0,11164467 ! actin filament-based movement GO:0030048 43 20 0,000 0,08412792 0,11158312 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,08412792 0,11152165 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08412792 0,11146023 ! negative regulation of translation GO:0017148 29 20 0,000 0,08412792 0,11139889 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08412792 0,11133762 ! regulation of cell killing GO:0031341 42 21 0,000 0,08814477 0,11658951 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08814477 0,11652545 ! hormone secretion GO:0046879 38 21 0,000 0,08814477 0,11646146 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08814477 0,11639754 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08814477 0,11633369 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08814477 0,11626992 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08814477 0,11620621 ! axis specification GO:0009798 38 21 0,000 0,08814477 0,11614257 ! ovarian follicle development GO:0001541 35 21 0,000 0,08814477 0,116079 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08814477 0,1160155 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08814477 0,11595206 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08814477 0,1158887 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08814477 0,11582541 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08814477 0,11576219 ! cytolysis GO:0019835 24 21 0,000 0,08814477 0,11569903 ! vasodilation GO:0042311 39 21 0,000 0,08814477 0,11563595 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08814477 0,11557293 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08814477 0,11550998 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08814477 0,1154471 ! oogenesis GO:0048477 36 21 0,000 0,08814477 0,11538429 ! DNA modification GO:0006304 34 21 0,000 0,08814477 0,11532155 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,08814477 0,11525887 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,08814477 0,11519627 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08814477 0,11513373 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08814477 0,11507126 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08814477 0,11500885 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08814477 0,11494652 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08814477 0,11488425 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08814477 0,11482205 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,08814477 0,11475992 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08814477 0,11469785 ! collagen catabolic process GO:0030574 28 21 0,000 0,08814477 0,11463585 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08814477 0,11457392 ! gut development GO:0048565 39 21 0,000 0,08814477 0,11451205 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09214414 0,11964317 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09214414 0,11957864 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09214414 0,11951418 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09214414 0,11944978 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09214414 0,11938546 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09214414 0,1193212 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09214414 0,11925702 ! regeneration GO:0031099 41 22 0,000 0,09214414 0,1191929 ! keratinization GO:0031424 28 22 0,000 0,09214414 0,11912885 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,09214414 0,11906488 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,09214414 0,11900096 ! sensory perception of taste GO:0050909 28 22 0,000 0,09214414 0,11893712 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09214414 0,11887335 ! vacuolar transport GO:0007034 36 22 0,000 0,09214414 0,11880965 ! lysosome organization GO:0007040 41 22 0,000 0,09214414 0,11874601 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09214414 0,11868244 ! fucose metabolic process GO:0006004 39 22 0,000 0,09214414 0,11861894 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09214414 0,11855551 ! ureteric bud development GO:0001657 43 22 0,000 0,09214414 0,11849214 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09214414 0,11842884 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,09214414 0,11836562 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09214414 0,11830245 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,09214414 0,11823936 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09214414 0,11817633 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09214414 0,11811337 ! sarcomere organization GO:0045214 30 22 0,000 0,09214414 0,11805048 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,09214414 0,11798765 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09214414 0,11792489 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,09214414 0,1178622 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09612609 0,12289021 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,09612609 0,12282495 ! gluconeogenesis GO:0006094 33 23 0,000 0,09612609 0,12275976 ! viral genome replication GO:0019079 41 23 0,000 0,09612609 0,12269463 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09612609 0,12262958 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09612609 0,12256459 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09612609 0,12249967 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09612609 0,12243483 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09612609 0,12237004 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09612609 0,12230533 ! visual behavior GO:0007632 42 23 0,000 0,09612609 0,12224069 ! response to ethanol GO:0045471 46 23 0,000 0,09612609 0,12217611 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09612609 0,12211161 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,09612609 0,12204717 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09612609 0,1219828 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09612609 0,12191849 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09612609 0,12185426 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09612609 0,12179009 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09612609 0,12172599 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09612609 0,12166196 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09612609 0,12159799 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09612609 0,1215341 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09612609 0,12147026 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09612609 0,1214065 ! fatty acid transport GO:0015908 44 23 0,000 0,09612609 0,1213428 ! platelet activation GO:0030168 37 23 0,000 0,09612609 0,12127917 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09612609 0,12121561 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09612609 0,12115211 ! hormone transport GO:0009914 40 23 0,000 0,09612609 0,12108868 ! cell-cell recognition GO:0009988 25 23 0,000 0,09612609 0,12102532 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09612609 0,12096202 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09612609 0,12089879 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09612609 0,12083562 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09612609 0,12077252 ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10009072 0,12568803 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10009072 0,12562247 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10009072 0,12555697 ! vesicle docking GO:0048278 47 24 0,000 0,10009072 0,12549154 ! spinal cord development GO:0021510 47 24 0,000 0,10009072 0,12542618 ! vacuole organization GO:0007033 43 24 0,000 0,10009072 0,12536089 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10009072 0,12529566 ! digestive system process GO:0022600 39 24 0,000 0,10009072 0,12523051 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10009072 0,12516542 ! regulation of behavior GO:0050795 43 24 0,000 0,10009072 0,1251004 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10009072 0,12503544 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10009072 0,12497056 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10009072 0,12490574 ! membrane depolarization GO:0051899 39 24 0,000 0,10009072 0,12484099 ! pallium development GO:0021543 49 24 0,000 0,10009072 0,1247763 ! pentose metabolic process GO:0019321 35 24 0,000 0,10009072 0,12471169 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,10009072 0,12464714 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10009072 0,12458265 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10009072 0,12451824 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10009072 0,12445388 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10009072 0,1243896 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10009072 0,12432538 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10009072 0,12426123 ! regulation of amine transport GO:0051952 40 24 0,000 0,10009072 0,12419715 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10403808 0,12902867 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10403808 0,1289622 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10403808 0,12889579 ! phototransduction GO:0007602 33 25 0,000 0,10403808 0,12882945 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10403808 0,12876318 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,10403808 0,12869698 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10403808 0,12863085 ! receptor metabolic process GO:0043112 46 25 0,000 0,10403808 0,12856478 ! chromosome condensation GO:0030261 45 25 0,000 0,10403808 0,12849878 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10403808 0,12843285 ! neural crest cell development GO:0014032 54 25 0,000 0,10403808 0,12836699 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10403808 0,12830119 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10403808 0,12823546 ! interaction with host GO:0051701 62 25 0,000 0,10403808 0,1281698 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10403808 0,12810421 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,10403808 0,12803868 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10403808 0,12797322 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,10403808 0,12790783 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10403808 0,1278425 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10403808 0,12777725 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10403808 0,12771205 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10403808 0,12764693 ! telomere organization GO:0032200 43 25 0,000 0,10403808 0,12758187 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10403808 0,12751687 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10403808 0,12745195 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10796826 0,13219931 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10796826 0,13213206 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,10796826 0,13206489 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,10796826 0,13199778 ! initiation of viral infection GO:0019059 57 26 0,000 0,10796826 0,13193075 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,10796826 0,13186378 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,10796826 0,13179687 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10796826 0,13173004 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10796826 0,13166327 ! molting cycle process GO:0022404 50 26 0,000 0,10796826 0,13159657 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,10796826 0,13152994 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,10796826 0,13146338 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,10796826 0,13139688 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,10796826 0,13133045 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,10796826 0,13126409 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,10796826 0,1311978 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,10796826 0,13113157 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,10796826 0,13106541 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10796826 0,13099931 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10796826 0,13093328 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,10796826 0,13086732 ! blastocyst development GO:0001824 49 26 0,000 0,10796826 0,13080143 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10796826 0,1307356 ! neuron fate commitment GO:0048663 48 27 0,000 0,11188133 0,13540568 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,11188133 0,1353376 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,11188133 0,13526959 ! iron ion transport GO:0006826 59 27 0,000 0,11188133 0,13520165 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,11188133 0,13513378 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,11188133 0,13506597 ! protein amino acid acylation GO:0043543 55 27 0,000 0,11188133 0,13499824 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,11188133 0,13493057 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,11188133 0,13486297 ! fat cell differentiation GO:0045444 50 27 0,000 0,11188133 0,13479544 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,11188133 0,13472797 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,11188133 0,13466057 ! autophagy GO:0006914 41 27 0,000 0,11188133 0,13459324 ! response to toxin GO:0009636 47 27 0,000 0,11188133 0,13452598 ! primary neural tube formation GO:0014020 51 27 0,000 0,11188133 0,13445878 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,11188133 0,13439165 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,11188133 0,13432459 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,11188133 0,1342576 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,11188133 0,13419067 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,11188133 0,13412381 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,11577737 0,13872527 ! circadian rhythm GO:0007623 50 28 0,000 0,11577737 0,13865622 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11577737 0,13858723 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11577737 0,13851832 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,11577737 0,13844947 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,11577737 0,1383807 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11577737 0,13831199 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,11577737 0,13824335 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,11577737 0,13817477 ! synaptogenesis GO:0007416 42 28 0,000 0,11577737 0,13810627 ! lipid oxidation GO:0034440 43 28 0,000 0,11577737 0,13803783 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11577737 0,13796946 ! translational initiation GO:0006413 65 29 0,000 0,11965644 0,14252148 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,11965644 0,14245096 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,11965644 0,14238051 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,11965644 0,14231013 ! catechol metabolic process GO:0009712 54 29 0,000 0,11965644 0,14223982 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,11965644 0,14216957 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,11965644 0,1420994 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,11965644 0,1420293 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,11965644 0,14195926 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,11965644 0,1418893 ! cell fate determination GO:0001709 60 29 0,000 0,11965644 0,1418194 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,11965644 0,14174958 ! detection of light stimulus GO:0009583 38 29 0,000 0,11965644 0,14167982 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,11965644 0,14161013 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,11965644 0,14154051 ! regulation of coagulation GO:0050818 46 29 0,000 0,11965644 0,14147095 ! phenol metabolic process GO:0018958 55 30 0,000 0,12351862 0,14596552 ! zinc ion transport GO:0006829 45 30 0,000 0,12351862 0,14589386 ! membrane docking GO:0022406 61 30 0,000 0,12351862 0,14582228 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,12351862 0,14575076 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12351862 0,14567931 ! acute-phase response GO:0006953 49 30 0,000 0,12351862 0,14560794 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12351862 0,14553663 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,12351862 0,14546539 ! phospholipid transport GO:0015914 51 30 0,000 0,12351862 0,14539423 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12351862 0,14532313 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12351862 0,1452521 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12351862 0,14518114 ! eye morphogenesis GO:0048592 60 30 0,000 0,12351862 0,14511025 ! response to heat GO:0009408 50 30 0,000 0,12351862 0,14503943 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12736399 0,14948183 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,12736399 0,14940895 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12736399 0,14933614 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12736399 0,1492634 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,12736399 0,14919073 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,12736399 0,14911813 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12736399 0,1490456 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,12736399 0,14897314 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12736399 0,14890075 ! ovulation cycle process GO:0022602 49 31 0,000 0,12736399 0,14882844 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,12736399 0,14875619 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,12736399 0,14868401 ! peptide transport GO:0015833 55 31 0,000 0,12736399 0,14861191 ! mesoderm formation GO:0001707 69 31 0,000 0,12736399 0,14853987 ! natural killer cell activation GO:0030101 45 31 0,000 0,12736399 0,1484679 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,12736399 0,14839601 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12736399 0,14832418 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,12736399 0,14825242 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,12736399 0,14818073 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,13119261 0,15256134 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13119261 0,15248764 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,13119261 0,15241401 ! cholesterol transport GO:0030301 56 32 0,000 0,13119261 0,15234045 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,13119261 0,15226696 ! spliceosome assembly GO:0000245 67 32 0,000 0,13119261 0,15219355 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13119261 0,1521202 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13119261 0,15204693 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,13119261 0,15197372 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,13119261 0,15190059 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,13119261 0,15182752 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13119261 0,15175453 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,13119261 0,1516816 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,13119261 0,15160875 ! ovulation cycle GO:0042698 51 32 0,000 0,13119261 0,15153597 ! BMP signaling pathway GO:0030509 64 32 0,000 0,13119261 0,15146325 ! hindbrain development GO:0030902 61 32 0,000 0,13119261 0,15139061 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,13119261 0,15131803 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13119261 0,15124553 ! gene silencing GO:0016458 65 32 0,000 0,13119261 0,15117309 ! post-embryonic development GO:0009791 69 33 0,000 0,13500456 0,15549113 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13500456 0,15541673 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13500456 0,15534241 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13500456 0,15526815 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13500456 0,15519397 ! cell fate specification GO:0001708 52 33 0,000 0,13500456 0,15511985 ! sterol transport GO:0015918 57 33 0,000 0,13500456 0,15504581 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,13500456 0,15497184 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13500456 0,15489794 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13500456 0,15482411 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13500456 0,15475035 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,13879991 0,15902504 ! glial cell differentiation GO:0010001 63 34 0,000 0,13879991 0,15894935 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,13879991 0,15887374 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,13879991 0,15879819 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,13879991 0,15872272 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,13879991 0,15864731 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,13879991 0,15857198 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,13879991 0,15849672 ! spermatid development GO:0007286 63 34 0,000 0,13879991 0,15842153 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,13879991 0,15834642 ! placenta development GO:0001890 53 34 0,000 0,13879991 0,15827137 ! regulation of muscle development GO:0048634 70 35 0,000 0,14257874 0,16250329 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,14257874 0,16242635 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,14257874 0,16234948 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,14257874 0,16227268 ! female gonad development GO:0008585 58 35 0,000 0,14257874 0,16219596 ! telencephalon development GO:0021537 68 35 0,000 0,14257874 0,1621193 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,14257874 0,16204272 ! cytokine production GO:0001816 59 35 0,000 0,14257874 0,16196622 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,14257874 0,16188978 ! neural tube formation GO:0001841 67 35 0,000 0,14257874 0,16181342 ! vesicle localization GO:0051648 64 35 0,000 0,14257874 0,16173713 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,14634111 0,16592682 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,14634111 0,16584866 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,14634111 0,16577058 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,14634111 0,16569257 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,14634111 0,16561463 ! positive regulation of cell development GO:0010720 80 36 0,000 0,14634111 0,16553677 ! regulation of proteolysis GO:0030162 72 36 0,000 0,14634111 0,16545898 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,14634111 0,16538126 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,14634111 0,16530362 ! aerobic respiration GO:0009060 55 36 0,000 0,14634111 0,16522605 ! embryonic organ development GO:0048568 57 36 0,000 0,14634111 0,16514855 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,14634111 0,16507113 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15008709 0,16921722 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,15008709 0,16913796 ! organic anion transport GO:0015711 68 37 0,000 0,15008709 0,16905878 ! tissue remodeling GO:0048771 76 37 0,000 0,15008709 0,16897967 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,15008709 0,16890063 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15008709 0,16882167 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,15008709 0,16874278 ! pigment metabolic process GO:0042440 80 37 0,000 0,15008709 0,16866397 ! spermatid differentiation GO:0048515 66 37 0,000 0,15008709 0,16858522 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,15381677 0,17269395 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,15381677 0,1726134 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,15381677 0,17253293 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,15381677 0,17245253 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,15381677 0,17237221 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,15381677 0,17229196 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,15381677 0,17221179 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,15381677 0,17213169 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,15381677 0,17205167 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,15381677 0,17197172 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,15381677 0,17189184 ! glucan metabolic process GO:0044042 62 38 0,000 0,15381677 0,17181204 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,15753019 0,17587826 ! learning GO:0007612 77 39 0,000 0,15753019 0,17579668 ! segmentation GO:0035282 67 39 0,000 0,15753019 0,17571518 ! ion transmembrane transport GO:0034220 66 39 0,000 0,15753019 0,17563376 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,15753019 0,17555241 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,15753019 0,17547113 ! RNA modification GO:0009451 57 39 0,000 0,15753019 0,17538993 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,15753019 0,17530881 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,16122745 0,17934038 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,16122745 0,1792575 ! feeding behavior GO:0007631 59 40 0,000 0,16122745 0,17917471 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,16122745 0,17909198 ! mesenchymal cell development GO:0014031 87 40 0,000 0,16122745 0,17900934 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,16122745 0,17892677 ! maintenance of protein location GO:0045185 91 40 0,000 0,16122745 0,17884428 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1649086 0,18284336 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,1649086 0,18275914 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,1649086 0,18267499 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1649086 0,18259093 ! gliogenesis GO:0042063 88 41 0,000 0,1649086 0,18250694 ! female gamete generation GO:0007292 61 41 0,000 0,1649086 0,18242303 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,1649086 0,18233919 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,16857372 0,18630609 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,16857372 0,18622055 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,16857372 0,18613509 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,16857372 0,18604971 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,16857372 0,1859644 ! regulation of protein secretion GO:0050708 71 42 0,000 0,16857372 0,18587918 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,17222287 0,18981595 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,17222287 0,18972904 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,17222287 0,18964221 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,17222287 0,18955545 ! neural tube development GO:0021915 77 43 0,000 0,17222287 0,18946878 ! phagocytosis GO:0006909 90 43 0,000 0,17222287 0,18938219 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,17222287 0,18929567 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,17585613 0,19320084 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,17585613 0,19311266 ! biopolymer methylation GO:0043414 84 44 0,000 0,17585613 0,19302456 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,17585613 0,19293654 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,17585613 0,1928486 ! developmental growth GO:0048589 82 44 0,000 0,17585613 0,19276075 ! maintenance of location in cell GO:0051651 97 44 0,000 0,17585613 0,19267297 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,17947356 0,19654683 ! leukocyte migration GO:0050900 68 45 0,000 0,17947356 0,19645741 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,17947356 0,19636807 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,17947356 0,19627881 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,17947356 0,19618963 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,17947356 0,19610053 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,17947356 0,19601152 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,17947356 0,19592258 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,18307523 0,19976372 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,18307523 0,19967316 ! positive regulation of defense response GO:0031349 76 47 0,000 0,18666121 0,20349201 ! response to calcium ion GO:0051592 81 47 0,000 0,18666121 0,20339985 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,18666121 0,20330777 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,18666121 0,20321578 ! methylation GO:0032259 90 47 0,000 0,18666121 0,20312387 ! protein homooligomerization GO:0051260 76 47 0,000 0,18666121 0,20303204 ! Notch signaling pathway GO:0007219 96 48 0,000 0,19023157 0,20682203 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,19023157 0,20672862 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,19023157 0,20663529 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,19023157 0,20654204 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,19023157 0,20644888 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,19378638 0,21021191 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,19378638 0,21011718 ! regulation of ion transport GO:0043269 77 49 0,000 0,19378638 0,21002253 ! response to temperature stimulus GO:0009266 76 49 0,000 0,19378638 0,20992797 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,19378638 0,20983349 ! endocrine system development GO:0035270 104 49 0,000 0,19378638 0,2097391 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,19378638 0,20964479 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,19378638 0,20955057 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,19732569 0,21328195 ! neuromuscular process GO:0050905 99 50 0,000 0,19732569 0,21318618 ! regulation of ossification GO:0030278 117 50 0,000 0,19732569 0,21309049 ! inner ear development GO:0048839 79 50 0,000 0,19732569 0,21299489 ! histone modification GO:0016570 91 50 0,000 0,19732569 0,21289938 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,19732569 0,21280395 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,19732569 0,21270861 ! viral infectious cycle GO:0019058 99 51 0,000 0,20084959 0,21641026 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,20084959 0,21631339 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,20084959 0,21621661 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,20084959 0,21611991 ! excretion GO:0007588 83 51 0,000 0,20084959 0,2160233 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,20084959 0,21592677 ! chromatin remodeling GO:0006338 109 51 0,000 0,20084959 0,21583033 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,20084959 0,21573398 ! vesicle organization GO:0016050 107 51 0,000 0,20084959 0,21563771 ! regulation of cell shape GO:0008360 125 51 0,000 0,20084959 0,21554153 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,20084959 0,21544544 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,20435813 0,21911126 ! membrane fusion GO:0006944 110 52 0,000 0,20435813 0,21901366 ! positive regulation of growth GO:0045927 90 52 0,000 0,20435813 0,21891615 ! covalent chromatin modification GO:0016569 101 52 0,000 0,20435813 0,21881872 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,20435813 0,21872138 ! amino acid activation GO:0043038 92 52 0,000 0,20435813 0,21862413 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,20435813 0,21852696 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,20785139 0,22216368 ! RNA catabolic process GO:0006401 93 53 0,000 0,20785139 0,22206503 ! regulation of translational initiation GO:0006446 82 53 0,000 0,20785139 0,22196646 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,20785139 0,22186799 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,20785139 0,2217696 ! cell maturation GO:0048469 100 53 0,000 0,20785139 0,22167129 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,21132942 0,22528072 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,21132942 0,22518095 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,21132942 0,22508127 ! cell recognition GO:0008037 85 54 0,000 0,21132942 0,22498168 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,21132942 0,22488217 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,21132942 0,22478275 ! chloride transport GO:0006821 90 55 0,000 0,2147923 0,22836512 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,2147923 0,22826426 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,2147923 0,22816348 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,2147923 0,22806279 ! gastrulation GO:0007369 112 55 0,000 0,2147923 0,22796219 ! heart morphogenesis GO:0003007 97 55 0,000 0,2147923 0,22786167 ! RNA elongation GO:0006354 79 55 0,000 0,2147923 0,22776125 ! nuclear export GO:0051168 97 55 0,000 0,2147923 0,22766091 ! sensory perception of smell GO:0007608 80 56 0,000 0,21824009 0,23121341 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,21824009 0,23111164 ! proton transport GO:0015992 94 56 0,000 0,21824009 0,23100997 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,22167285 0,23454041 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,22167285 0,23443731 ! maintenance of location GO:0051235 118 57 0,000 0,22167285 0,23433431 ! hydrogen transport GO:0006818 97 58 0,000 0,22509066 0,23784283 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,22509066 0,23773842 ! regulation of endocytosis GO:0030100 91 58 0,000 0,22509066 0,2376341 ! adult behavior GO:0030534 99 58 0,000 0,22509066 0,23752988 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,22509066 0,23742574 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,22849357 0,24090952 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,22849357 0,24080399 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,23188164 0,24426762 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,23188164 0,24416072 ! regulation of heart contraction GO:0008016 110 60 0,000 0,23188164 0,24405391 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,23188164 0,2439472 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,23525496 0,24738786 ! mesoderm development GO:0007498 119 61 0,000 0,23525496 0,24727978 ! tRNA processing GO:0008033 89 61 0,000 0,23525496 0,2471718 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,23525496 0,24706391 ! viral reproductive process GO:0022415 126 62 0,000 0,23861356 0,25048178 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,23861356 0,25037254 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,24195753 0,25377063 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,24195753 0,25366006 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,24528693 0,25703848 ! cell redox homeostasis GO:0045454 102 64 0,000 0,24528693 0,25692658 ! single fertilization GO:0007338 75 64 0,000 0,24528693 0,25681477 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,24860181 0,26017223 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,24860181 0,26005911 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,24860181 0,25994609 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,25190224 0,26328271 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,25190224 0,26316838 ! secondary metabolic process GO:0019748 116 66 0,000 0,25190224 0,26305416 ! developmental maturation GO:0021700 116 66 0,000 0,25190224 0,26294004 ! cell projection assembly GO:0030031 120 66 0,000 0,25190224 0,26282601 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,25518828 0,26613915 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,25518828 0,26602384 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,25518828 0,26590862 ! activation of immune response GO:0002253 105 67 0,000 0,25518828 0,26579351 ! amino acid transport GO:0006865 125 68 0,000 0,25846 0,26908471 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,25846 0,26896832 ! viral reproduction GO:0016032 134 68 0,000 0,25846 0,26885204 ! regulation of lipase activity GO:0060191 130 68 0,000 0,25846 0,26873585 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,25846 0,26861977 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,26171746 0,27188783 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,26171746 0,27177048 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,26171746 0,27165324 ! antigen processing and presentation GO:0019882 104 69 0,000 0,26171746 0,2715361 ! appendage morphogenesis GO:0035107 135 70 0,000 0,26496071 0,27478253 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,26818983 0,27801151 ! appendage development GO:0048736 136 71 0,000 0,26818983 0,27789178 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,26818983 0,27777216 ! regulation of immune effector process GO:0002697 137 71 0,000 0,26818983 0,27765263 ! acute inflammatory response GO:0002526 113 72 0,000 0,27140486 0,28086026 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,27140486 0,28073951 ! learning or memory GO:0007611 147 73 0,000 0,27460588 0,28392855 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,27460588 0,28380659 ! fertilization GO:0009566 90 73 0,000 0,27460588 0,28368473 ! transition metal ion transport GO:0000041 126 74 0,000 0,27779294 0,286854 ! neurotransmitter transport GO:0006836 123 74 0,000 0,27779294 0,28673093 ! exocytosis GO:0006887 133 74 0,000 0,27779294 0,28660798 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,2809661 0,28975758 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,2809661 0,28963344 ! rhythmic process GO:0048511 128 75 0,000 0,2809661 0,2895094 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,28412543 0,29263946 ! defense response to bacterium GO:0042742 89 76 0,000 0,28412543 0,29251424 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,28412543 0,29238913 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,28727098 0,29549977 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,28727098 0,29537349 ! blood coagulation GO:0007596 146 78 0,000 0,29040281 0,29846611 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,29040281 0,29833867 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,29040281 0,29821133 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,29352098 0,30128476 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,29352098 0,30115628 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,29352098 0,30102791 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,29662556 0,30408227 ! response to metal ion GO:0010038 140 80 0,000 0,29662556 0,30395276 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,29662556 0,30382337 ! inorganic anion transport GO:0015698 138 80 0,000 0,29662556 0,30369408 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,29971659 0,30672825 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,29971659 0,30659784 ! digestion GO:0007586 112 81 0,000 0,29971659 0,30646754 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,29971659 0,30633735 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,29971659 0,30620727 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,30279415 0,30922017 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,30279415 0,30908898 ! response to nutrient GO:0007584 125 82 0,000 0,30279415 0,3089579 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,30279415 0,30882693 ! response to oxygen levels GO:0070482 176 83 0,000 0,30585828 0,31181992 ! regulation of lyase activity GO:0051339 160 83 0,000 0,30585828 0,31168785 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,30890904 0,31466349 ! hemostasis GO:0007599 158 84 0,000 0,30890904 0,31453033 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,30890904 0,31439728 ! response to unfolded protein GO:0006986 131 85 0,000 0,3119465 0,31735445 ! nucleosome assembly GO:0006334 122 85 0,000 0,3119465 0,31722032 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,3119465 0,31708631 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,3119465 0,3169524 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 0,000 0,31497071 0,31989005 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,31497071 0,31975508 ! chromatin assembly GO:0031497 124 86 0,000 0,31497071 0,31962022 ! tube morphogenesis GO:0035239 176 86 0,000 0,31497071 0,31948547 ! amine transport GO:0015837 155 86 0,000 0,31497071 0,31935084 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,31798173 0,32226792 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,31798173 0,32213223 ! cellular respiration GO:0045333 135 88 0,000 0,32097961 0,32503239 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,32097961 0,32489564 ! regulation of neurological system process GO:0031644 148 88 0,000 0,32097961 0,32475902 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,32097961 0,32462251 ! cellular defense response GO:0006968 114 89 0,000 0,32396442 0,32750352 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,32396442 0,32736598 ! ossification GO:0001503 188 90 0,000 0,3269362 0,33023027 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,3269362 0,33009169 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,3269362 0,32995323 ! bone development GO:0060348 189 91 0,000 0,32989502 0,33279975 ! sterol metabolic process GO:0016125 152 91 0,000 0,32989502 0,33266027 ! response to protein stimulus GO:0051789 149 91 0,000 0,32989502 0,33252091 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,32989502 0,33238166 ! regulation of defense response GO:0031347 149 92 0,000 0,33284093 0,3352094 ! nucleosome organization GO:0034728 138 92 0,000 0,33284093 0,33506915 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,33284093 0,33492901 ! vitamin metabolic process GO:0006766 139 92 0,000 0,33284093 0,33478899 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,33577398 0,33759808 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,33577398 0,33745706 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,33577398 0,33731616 ! female pregnancy GO:0007565 164 94 0,000 0,33869424 0,34010782 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,34160176 0,34288437 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,34449659 0,34564587 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,34449659 0,34550179 ! positive regulation of immune response GO:0050778 156 96 0,000 0,34449659 0,34535783 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,34737878 0,34810219 ! response to virus GO:0009615 160 98 0,000 0,3502484 0,35083166 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,3502484 0,35068567 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,3502484 0,35053979 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,3531055 0,35325232 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,3531055 0,3531055