pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6614-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cell cycle checkpoint GO:0000075 145 71 8,000 9,978E-12 2,438E-08 ! regulation of protein export from nucleus GO:0046825 10 7 4,000 1,775E-11 2,168E-08 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 5,000 3,832E-11 3,12E-08 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 7,000 6,274E-11 3,832E-08 ! DNA damage checkpoint GO:0000077 78 35 6,000 7,369E-11 3,601E-08 ! apoptotic mitochondrial changes GO:0008637 42 20 5,000 1,189E-10 4,84E-08 ! DNA damage response, signal transduction GO:0042770 136 62 7,000 1,263E-10 4,407E-08 ! DNA integrity checkpoint GO:0031570 82 38 6,000 1,37E-10 4,182E-08 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 4,000 3,857E-10 1,047E-07 GO:0010812|negative regulation of cell-substrate adhesion, ! phospholipid dephosphorylation GO:0046839 12 5 3,000 1,116E-09 2,727E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 3,339E-09 7,415E-07 ! endothelial cell migration GO:0043542 31 17 4,000 5,069E-09 1,032E-06 ! cardiac muscle tissue development GO:0048738 34 17 4,000 5,069E-09 9,526E-07 ! organ growth GO:0035265 15 7 3,000 7,767E-09 1,355E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 7,767E-09 1,265E-06 GO:0046676|negative regulation of insulin secretion, ! negative regulation of focal adhesion formation GO:0051895 21 7 3,000 7,767E-09 1,186E-06 ! regulation of protein stability GO:0031647 77 38 5,000 7,99E-09 1,148E-06 ! inositol metabolic process GO:0006020 33 19 4,000 9,466E-09 1,285E-06 ! regulation of focal adhesion formation GO:0051893 23 8 3,000 1,549E-08 1,991E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 1,549E-08 1,892E-06 ! regulation of cell-matrix adhesion GO:0001952 81 23 4,000 2,705E-08 3,147E-06 GO:0010810|regulation of cell-substrate adhesion, ! nerve growth factor receptor signaling pathway GO:0048011 20 9 3,000 2,779E-08 3,086E-06 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 3,000 4,618E-08 4,905E-06 ! positive regulation of MAP kinase activity GO:0043406 174 93 6,000 8,598E-08 8,752E-06 ! negative regulation of mast cell proliferation GO:0070667 24 12 3,000 1,082E-07 1,057E-05 GO:0042130|negative regulation of T cell proliferation, ! oxygen transport GO:0015671 22 14 3,000 2,175E-07 2,043E-05 ! release of cytochrome c from mitochondria GO:0001836 31 14 3,000 2,175E-07 1,968E-05 ! negative regulation of cell adhesion GO:0007162 94 37 4,000 3,353E-07 2,926E-05 ! meiosis I GO:0007127 74 38 4,000 3,849E-07 3,243E-05 ! negative regulation of leukocyte proliferation GO:0070664 32 16 3,000 3,93E-07 3,2E-05 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of hormone secretion GO:0046888 26 17 3,000 5,123E-07 4,038E-05 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 3,000 5,123E-07 3,911E-05 ! gas transport GO:0015669 26 17 3,000 5,123E-07 3,793E-05 ! regulation of intracellular protein transport GO:0033157 86 42 4,000 6,442E-07 4,629E-05 ! meiosis GO:0007126 143 81 5,000 8,184E-07 5,712E-05 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of hormone secretion GO:0046887 35 19 3,000 8,293E-07 5,628E-05 ! meiotic cell cycle GO:0051321 144 82 5,000 8,802E-07 5,812E-05 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 9,166E-07 5,893E-05 ! polyol metabolic process GO:0019751 77 45 4,000 9,166E-07 5,741E-05 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 4,000 1,025E-06 6,261E-05 ! negative regulation of T cell activation GO:0050868 41 20 3,000 1,034E-06 6,158E-05 ! negative regulation of B cell activation GO:0050869 14 6 2,000 1,16E-06 6,75E-05 ! mitochondrion organization GO:0007005 159 87 5,000 1,249E-06 7,097E-05 ! cell structure disassembly during apoptosis GO:0006921 32 21 3,000 1,273E-06 7,067E-05 ! apoptotic nuclear changes GO:0030262 34 22 3,000 1,551E-06 8,42E-05 ! regulation of cell adhesion GO:0030155 241 92 5,000 1,736E-06 9,219E-05 ! regulation of helicase activity GO:0051095 16 7 2,000 2,025E-06 1,053E-04 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 3,000 2,239E-06 1,14E-04 ! regulation of DNA metabolic process GO:0051052 188 97 5,000 2,367E-06 1,18E-04 ! regulation of insulin secretion GO:0050796 42 25 3,000 2,658E-06 1,299E-04 ! regulation of intracellular transport GO:0032386 108 57 4,000 3,025E-06 1,449E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 3,231E-06 1,518E-04 ! dendrite morphogenesis GO:0048813 14 8 2,000 3,231E-06 1,489E-04 ! negative regulation of lymphocyte activation GO:0051250 55 27 3,000 3,665E-06 1,658E-04 ! axon extension GO:0048675 16 9 2,000 4,832E-06 2,146E-04 ! regulation of peptide secretion GO:0002791 52 29 3,000 4,93E-06 2,151E-04 ! negative regulation of protein kinase cascade GO:0010741 72 30 3,000 5,671E-06 2,431E-04 ! negative regulation of leukocyte activation GO:0002695 60 31 3,000 6,492E-06 2,734E-04 ! activation of MAPK activity GO:0000187 124 67 4,000 6,762E-06 2,8E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 6,883E-06 2,803E-04 ! central nervous system neuron axonogenesis GO:0021955 23 10 2,000 6,883E-06 2,757E-04 GO:0021952|central nervous system projection neuron axonogenesis, ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 7,82E-06 3,081E-04 ! triglyceride metabolic process GO:0006641 46 33 3,000 8,391E-06 3,254E-04 ! negative regulation of kinase activity GO:0033673 145 70 4,000 8,395E-06 3,205E-04 ! negative regulation of secretion GO:0051048 68 35 3,000 1,067E-05 4,011E-04 ! negative regulation of transferase activity GO:0051348 155 74 4,000 1,103E-05 4,084E-04 ! regulation of B cell proliferation GO:0030888 22 12 2,000 1,255E-05 4,575E-04 ! negative regulation of cell activation GO:0050866 69 37 3,000 1,338E-05 4,807E-04 ! neutral lipid metabolic process GO:0006638 54 38 3,000 1,491E-05 5,279E-04 GO:0006639|acylglycerol metabolic process, ! carbohydrate homeostasis GO:0033500 59 39 3,000 1,656E-05 5,78E-04 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 73 40 3,000 1,835E-05 6,313E-04 ! glycerol ether metabolic process GO:0006662 57 40 3,000 1,835E-05 6,225E-04 ! regulation of hormone secretion GO:0046883 69 41 3,000 2,027E-05 6,783E-04 ! negative regulation of transport GO:0051051 164 85 4,000 2,171E-05 7,167E-04 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 2,171E-05 7,071E-04 ! organic ether metabolic process GO:0018904 59 42 3,000 2,233E-05 7,179E-04 ! regulation of protein transport GO:0051223 165 87 4,000 2,43E-05 7,71E-04 GO:0070201|regulation of establishment of protein localization, ! hormone-mediated signaling GO:0009755 84 43 3,000 2,455E-05 7,689E-04 ! regulation of T cell proliferation GO:0042129 80 43 3,000 2,455E-05 7,592E-04 ! negative regulation of cell migration GO:0030336 122 46 3,000 3,217E-05 9,824E-04 ! cellular component disassembly GO:0022411 89 48 3,000 3,813E-05 1,15E-03 ! regulation of protein localization GO:0032880 188 97 4,000 4,108E-05 1,224E-03 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 4,139E-05 1,218E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 4,315E-05 1,255E-03 ! activation of caspase activity GO:0006919 95 50 3,000 4,485E-05 1,289E-03 ! negative regulation of immune system process GO:0002683 101 51 3,000 4,852E-05 1,378E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 5,652E-05 1,587E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of multicellular organism growth GO:0040014 90 55 3,000 6,543E-05 1,816E-03 ! response to UV GO:0009411 120 55 3,000 6,543E-05 1,796E-03 ! negative regulation of cell motion GO:0051271 142 55 3,000 6,543E-05 1,776E-03 ! positive regulation of caspase activity GO:0043280 108 57 3,000 7,532E-05 2,022E-03 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 112 58 3,000 8,065E-05 2,142E-03 ! reciprocal meiotic recombination GO:0007131 44 22 2,000 8,535E-05 2,242E-03 ! central nervous system neuron development GO:0021954 47 22 2,000 8,535E-05 2,218E-03 ! DNA catabolic process GO:0006308 94 60 3,000 9,214E-05 2,369E-03 ! lipid modification GO:0030258 112 60 3,000 9,214E-05 2,345E-03 ! regulation of DNA recombination GO:0000018 51 23 2,000 9,787E-05 2,465E-03 ! positive regulation of secretion GO:0051047 110 61 3,000 9,831E-05 2,451E-03 ! central nervous system neuron differentiation GO:0021953 51 24 2,000 1,115E-04 2,752E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 1,186E-04 2,898E-03 ! multicellular organism reproduction GO:0032504 123 65 3,000 1,26E-04 3,048E-03 GO:0048609|reproductive process in a multicellular organism, ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 1,264E-04 3,027E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 1,264E-04 2,997E-03 ! negative regulation of cell growth GO:0030308 142 67 3,000 1,418E-04 3,331E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 1,425E-04 3,314E-03 ! positive regulation of helicase activity GO:0051096 12 5 1,000 1,507E-04 3,472E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,507E-04 3,44E-03 ! skeletal myofibril assembly GO:0014866 12 5 1,000 1,507E-04 3,408E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,507E-04 3,377E-03 ! cardiac muscle fiber development GO:0048739 12 5 1,000 1,507E-04 3,346E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 1,507E-04 3,316E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 1,507E-04 3,286E-03 ! B cell homeostasis GO:0001782 13 5 1,000 1,507E-04 3,257E-03 ! stem cell division GO:0017145 11 5 1,000 1,507E-04 3,229E-03 GO:0048103|somatic stem cell division, ! negative regulation of cell size GO:0045792 144 69 3,000 1,59E-04 3,377E-03 ! urogenital system development GO:0001655 149 69 3,000 1,59E-04 3,348E-03 ! regulation of chromosome organization GO:0033044 49 27 2,000 1,598E-04 3,337E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 1,785E-04 3,695E-03 ! dendrite development GO:0016358 67 28 2,000 1,785E-04 3,664E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 1,785E-04 3,633E-03 ! regulation of caspase activity GO:0043281 136 74 3,000 2,084E-04 4,208E-03 ! regulation of B cell activation GO:0050864 55 30 2,000 2,199E-04 4,404E-03 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 2,254E-04 4,477E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 2,254E-04 4,441E-03 ! neuron apoptosis GO:0051402 15 6 1,000 2,254E-04 4,406E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 2,254E-04 4,371E-03 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 2,254E-04 4,336E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 2,254E-04 4,302E-03 ! determination of adult lifespan GO:0008340 17 6 1,000 2,254E-04 4,269E-03 ! phosphoinositide metabolic process GO:0030384 146 77 3,000 2,429E-04 4,565E-03 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 2,429E-04 4,53E-03 ! regulation of peptidase activity GO:0052547 150 82 3,000 3,092E-04 5,723E-03 ! prostate gland development GO:0030850 14 7 1,000 3,148E-04 5,782E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 3,148E-04 5,739E-03 ! induction of apoptosis by oxidative stress GO:0008631 9 7 1,000 3,148E-04 5,696E-03 ! negative regulation of DNA recombination GO:0045910 16 7 1,000 3,148E-04 5,654E-03 ! centrosome duplication GO:0051298 14 7 1,000 3,148E-04 5,613E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 3,148E-04 5,573E-03 ! anterograde axon cargo transport GO:0008089 18 7 1,000 3,148E-04 5,532E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 3,148E-04 5,493E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 3,148E-04 5,454E-03 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 3,495E-04 6,013E-03 ! negative regulation of growth GO:0045926 168 85 3,000 3,548E-04 6,061E-03 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 1,000 4,186E-04 7,102E-03 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of lipid kinase activity GO:0043550 17 8 1,000 4,186E-04 7,053E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 4,186E-04 7,005E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,186E-04 6,957E-03 ! ER overload response GO:0006983 13 8 1,000 4,186E-04 6,91E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 4,186E-04 6,864E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 4,186E-04 6,818E-03 ! multicellular organismal aging GO:0010259 20 8 1,000 4,186E-04 6,773E-03 ! response to tumor cell GO:0002347 16 8 1,000 4,186E-04 6,728E-03 ! regulation of cell cycle process GO:0010564 161 90 3,000 4,41E-04 7,041E-03 ! regulation of activated T cell proliferation GO:0046006 19 9 1,000 5,369E-04 8,517E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 5,369E-04 8,462E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 5,369E-04 8,407E-03 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 5,369E-04 8,354E-03 ! regulation of telomere maintenance GO:0032204 17 9 1,000 5,369E-04 8,301E-03 ! sex differentiation GO:0007548 171 96 3,000 5,63E-04 8,651E-03 ! regulation of T cell activation GO:0050863 175 96 3,000 5,63E-04 8,597E-03 ! regulation of T cell differentiation GO:0045580 78 42 2,000 6,009E-04 9,117E-03 ! striated muscle cell differentiation GO:0051146 91 43 2,000 6,441E-04 9,713E-03 ! development of primary male sexual characteristics GO:0046546 80 43 2,000 6,441E-04 9,653E-03 ! neuron migration GO:0001764 85 43 2,000 6,441E-04 9,594E-03 ! hormone metabolic process GO:0042445 171 100 3,000 6,567E-04 9,723E-03 ! elastic fiber assembly GO:0048251 17 10 1,000 6,694E-04 9,851E-03 ! pathogenesis GO:0009405 17 10 1,000 6,694E-04 9,792E-03 ! polyamine biosynthetic process GO:0006596 13 10 1,000 6,694E-04 9,734E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 6,694E-04 9,676E-03 ! motor axon guidance GO:0008045 22 10 1,000 6,694E-04 9,619E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 7,855E-04 0,01122207 ! glycolysis GO:0006096 71 46 2,000 7,855E-04 0,01115682 ! pigmentation GO:0043473 103 46 2,000 7,855E-04 0,01109233 ! detection of mechanical stimulus GO:0050982 22 11 1,000 8,16E-04 0,01145686 ! regulation of intracellular pH GO:0051453 21 11 1,000 8,16E-04 0,01139139 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 1,000 8,16E-04 0,01132666 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! endosome transport GO:0016197 127 48 2,000 8,899E-04 0,01228265 ! male sex differentiation GO:0046661 93 48 2,000 8,899E-04 0,01221364 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 9,452E-04 0,01290066 ! T cell proliferation GO:0042098 32 12 1,000 9,767E-04 0,01325589 ! focal adhesion formation GO:0048041 37 12 1,000 9,767E-04 0,01318266 ! immunoglobulin production during immune response GO:0002381 24 12 1,000 9,767E-04 0,01311022 ! T cell homeostasis GO:0043029 28 12 1,000 9,767E-04 0,01303858 ! polyamine metabolic process GO:0006595 18 12 1,000 9,767E-04 0,01296772 ! response to X-ray GO:0010165 28 13 1,000 1,151E-03 0,0152036 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 2,000 1,323E-03 0,01737893 ! regulation of cellular pH GO:0030641 27 14 1,000 1,34E-03 0,01750288 ! response to gamma radiation GO:0010332 30 14 1,000 1,34E-03 0,01740978 ! male genitalia development GO:0030539 26 14 1,000 1,34E-03 0,01731767 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 1,34E-03 0,01722652 ! glucose catabolic process GO:0006007 88 56 2,000 1,394E-03 0,01783108 ! regulation of protein catabolic process GO:0042176 126 56 2,000 1,394E-03 0,01773821 ! regulation of DNA replication GO:0006275 105 56 2,000 1,394E-03 0,01764631 ! regulation of mRNA processing GO:0050684 26 15 1,000 1,542E-03 0,01941708 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,542E-03 0,01931751 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,542E-03 0,01921895 ! lymphocyte homeostasis GO:0002260 33 15 1,000 1,542E-03 0,01912139 ! regulation of actin filament length GO:0030832 118 58 2,000 1,543E-03 0,0190379 ! positive regulation of cell migration GO:0030335 137 58 2,000 1,543E-03 0,01894223 ! positive regulation of organelle organization GO:0010638 108 58 2,000 1,543E-03 0,01884752 ! kidney development GO:0001822 133 60 2,000 1,701E-03 0,02068027 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 1,758E-03 0,02125755 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 1,000 1,758E-03 0,02115283 ! axon cargo transport GO:0008088 46 16 1,000 1,758E-03 0,02104914 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,758E-03 0,02094646 ! regulation of cellular component size GO:0032535 125 61 2,000 1,784E-03 0,02116173 ! camera-type eye development GO:0043010 126 61 2,000 1,784E-03 0,0210595 ! regulation of mitosis GO:0007088 112 63 2,000 1,958E-03 0,02299392 GO:0051783|regulation of nuclear division, ! negative regulation of cell cycle process GO:0010948 35 17 1,000 1,987E-03 0,0232254 ! activation of MAPKK activity GO:0000186 43 17 1,000 1,987E-03 0,0231148 ! regulation of survival gene product expression GO:0045884 38 17 1,000 1,987E-03 0,02300525 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 1,987E-03 0,02289674 ! genitalia development GO:0048806 32 17 1,000 1,987E-03 0,02278924 ! positive regulation of cell motion GO:0051272 157 65 2,000 2,141E-03 0,02444355 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 2,23E-03 0,02533443 ! centrosome cycle GO:0007098 26 18 1,000 2,23E-03 0,02521714 ! cell-substrate junction assembly GO:0007044 56 18 1,000 2,23E-03 0,02510094 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 2,23E-03 0,02498579 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 2,23E-03 0,0248717 ! hexose catabolic process GO:0019320 113 68 2,000 2,436E-03 0,02704865 ! extracellular matrix organization GO:0030198 146 68 2,000 2,436E-03 0,02692626 ! pigmentation during development GO:0048066 42 19 1,000 2,486E-03 0,02735201 ! neuromuscular junction development GO:0007528 43 19 1,000 2,486E-03 0,02722936 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 1,000 2,486E-03 0,0271078 ! homeostasis of number of cells GO:0048872 131 69 2,000 2,539E-03 0,02757128 ! response to alkaloid GO:0043279 38 20 1,000 2,755E-03 0,02977691 ! actin filament bundle formation GO:0051017 47 20 1,000 2,755E-03 0,02964573 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 2,755E-03 0,02951571 ! B cell activation GO:0042113 179 72 2,000 2,866E-03 0,03057449 ! smooth muscle contraction GO:0006939 48 21 1,000 3,037E-03 0,0322563 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 3,037E-03 0,03211666 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 3,037E-03 0,03197823 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 3,037E-03 0,03184098 ! regulation of transcription factor activity GO:0051090 137 75 2,000 3,217E-03 0,03358977 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 2,000 3,217E-03 0,03344683 ! eye development GO:0001654 155 75 2,000 3,217E-03 0,03330511 ! axon guidance GO:0007411 162 75 2,000 3,217E-03 0,03316458 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 3,332E-03 0,03420165 ! microtubule-based transport GO:0010970 59 22 1,000 3,332E-03 0,03405855 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 3,332E-03 0,03391664 ! cellular response to starvation GO:0009267 37 22 1,000 3,332E-03 0,03377591 ! cell aging GO:0007569 48 22 1,000 3,332E-03 0,03363634 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 3,332E-03 0,03349792 ! G1 phase GO:0051318 44 22 1,000 3,332E-03 0,03336063 ! activation of JUN kinase activity GO:0007257 47 22 1,000 3,332E-03 0,03322446 ! somatic diversification of immunoglobulins GO:0016445 55 22 1,000 3,332E-03 0,03308941 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 3,332E-03 0,03295544 ! protein stabilization GO:0050821 41 22 1,000 3,332E-03 0,03282256 ! regulation of actin cytoskeleton organization GO:0032956 167 76 2,000 3,34E-03 0,0327704 ! monosaccharide catabolic process GO:0046365 125 77 2,000 3,466E-03 0,03386631 ! regulation of catabolic process GO:0009894 173 77 2,000 3,466E-03 0,03373138 ! positive regulation of DNA replication GO:0045740 44 23 1,000 3,64E-03 0,03528754 ! regulation of anti-apoptosis GO:0045767 62 23 1,000 3,64E-03 0,03514806 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 3,64E-03 0,03500969 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 3,64E-03 0,03487239 ! regulation of actin filament-based process GO:0032970 170 79 2,000 3,725E-03 0,03555093 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 3,725E-03 0,0354126 ! development of primary sexual characteristics GO:0045137 143 80 2,000 3,86E-03 0,03654592 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 1,000 3,961E-03 0,03735944 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 3,961E-03 0,03721575 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 3,961E-03 0,03707316 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 3,961E-03 0,03693166 ! sex determination GO:0007530 48 24 1,000 3,961E-03 0,03679124 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 3,961E-03 0,03665188 ! negative regulation of catabolic process GO:0009895 52 24 1,000 3,961E-03 0,03651357 ! muscle cell differentiation GO:0042692 178 81 2,000 3,997E-03 0,03670591 ! protein import into nucleus GO:0006606 174 82 2,000 4,137E-03 0,03784966 ! nuclear import GO:0051170 177 83 2,000 4,28E-03 0,03901177 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 4,294E-03 0,03899869 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 4,294E-03 0,03885425 ! vasculogenesis GO:0001570 49 25 1,000 4,294E-03 0,03871088 ! negative regulation of DNA replication GO:0008156 45 25 1,000 4,294E-03 0,03856856 ! lymphocyte proliferation GO:0046651 55 25 1,000 4,294E-03 0,03842728 ! immunoglobulin production GO:0002377 62 25 1,000 4,294E-03 0,03828704 GO:0002440|production of molecular mediator of immune response, ! leukocyte homeostasis GO:0001776 50 25 1,000 4,294E-03 0,03814781 ! protein tetramerization GO:0051262 57 25 1,000 4,294E-03 0,0380096 ! T cell activation GO:0042110 189 84 2,000 4,426E-03 0,03903141 ! regulation of ligase activity GO:0051340 147 84 2,000 4,426E-03 0,03889101 ! myelination GO:0042552 50 26 1,000 4,64E-03 0,04063035 ! microtubule organizing center organization GO:0031023 42 26 1,000 4,64E-03 0,04048524 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 4,64E-03 0,04034117 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,64E-03 0,04019811 ! negative regulation of cell development GO:0010721 83 26 1,000 4,64E-03 0,04005607 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 1,000 4,64E-03 0,03991503 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 1,000 4,64E-03 0,03977498 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 4,64E-03 0,0396359 ! alcohol catabolic process GO:0046164 142 87 2,000 4,881E-03 0,04155152 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 4,999E-03 0,04240106 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 4,999E-03 0,04225435 ! mitochondrial membrane organization GO:0007006 60 27 1,000 4,999E-03 0,04210864 ! response to starvation GO:0042594 47 27 1,000 4,999E-03 0,04196394 ! cellular response to nutrient levels GO:0031669 45 27 1,000 4,999E-03 0,04182023 ! leukocyte proliferation GO:0070661 59 27 1,000 4,999E-03 0,04167749 GO:0032943|mononuclear cell proliferation, ! regulation of DNA binding GO:0051101 167 89 2,000 5,2E-03 0,0432133 ! protein localization in nucleus GO:0034504 192 89 2,000 5,2E-03 0,04306681 ! base-excision repair GO:0006284 41 28 1,000 5,369E-03 0,04431525 ! glutathione metabolic process GO:0006749 42 28 1,000 5,369E-03 0,04416604 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 5,369E-03 0,04401783 ! gland development GO:0048732 220 91 2,000 5,532E-03 0,04519778 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 5,752E-03 0,04684349 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 5,752E-03 0,04668787 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 6,148E-03 0,04973001 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 6,148E-03 0,04956588 GO:0048871|multicellular organismal homeostasis, ! myofibril assembly GO:0030239 50 30 1,000 6,148E-03 0,04940284 GO:0055002|striated muscle cell development, ! cell junction assembly GO:0034329 85 31 1,000 6,555E-03 0,05250267 ! male gonad development GO:0008584 56 31 1,000 6,555E-03 0,05233109 ! iron ion homeostasis GO:0055072 60 31 1,000 6,555E-03 0,05216063 ! erythrocyte differentiation GO:0030218 62 31 1,000 6,555E-03 0,05199128 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 6,555E-03 0,05182302 ! ensheathment of neurons GO:0007272 64 31 1,000 6,555E-03 0,05165585 GO:0008366|axon ensheathment, ! forebrain development GO:0030900 210 98 2,000 6,79E-03 0,05333666 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 6,974E-03 0,05460693 ! spindle organization GO:0007051 50 32 1,000 6,974E-03 0,05443247 ! metanephros development GO:0001656 81 32 1,000 6,974E-03 0,05425911 ! response to mechanical stimulus GO:0009612 60 32 1,000 6,974E-03 0,05408686 ! muscle cell development GO:0055001 52 32 1,000 6,974E-03 0,0539157 ! peripheral nervous system development GO:0007422 68 32 1,000 6,974E-03 0,05374562 ! positive regulation of catabolic process GO:0009896 72 32 1,000 6,974E-03 0,05357661 ! regulation of pH GO:0006885 56 33 1,000 7,405E-03 0,05670961 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 7,405E-03 0,05653239 ! response to ionizing radiation GO:0010212 74 33 1,000 7,405E-03 0,05635628 ! negative regulation of protein transport GO:0051224 74 33 1,000 7,405E-03 0,05618126 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 7,848E-03 0,0593563 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 8,302E-03 0,06259965 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 8,768E-03 0,06590994 ! negative regulation of DNA binding GO:0043392 67 36 1,000 8,768E-03 0,06570776 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 8,768E-03 0,06550682 ! sister chromatid segregation GO:0000819 65 37 1,000 9,246E-03 0,06886336 ! odontogenesis GO:0042476 74 37 1,000 9,246E-03 0,06865405 ! actomyosin structure organization GO:0031032 68 37 1,000 9,246E-03 0,06844601 ! cell junction organization GO:0034330 96 37 1,000 9,246E-03 0,06823922 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 9,246E-03 0,06803368 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 9,735E-03 0,07141565 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 9,735E-03 0,07120183 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 9,735E-03 0,07098928 ! negative regulation of binding GO:0051100 71 39 1,000 0,01023462 0,07441423 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01023462 0,07419342 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01023462 0,07397391 ! mammary gland development GO:0030879 93 40 1,000 0,01074591 0,07744032 ! mismatch repair GO:0006298 58 40 1,000 0,01074591 0,07721255 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01074591 0,07698612 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01126829 0,08049251 ! ear morphogenesis GO:0042471 64 42 1,000 0,01180166 0,08405675 ! T cell differentiation GO:0030217 93 42 1,000 0,01180166 0,0838124 ! cytokinesis GO:0000910 84 42 1,000 0,01180166 0,08356947 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01234594 0,08717087 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,01234594 0,08691966 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,01234594 0,08666989 ! regulation of tube size GO:0035150 76 43 1,000 0,01234594 0,08642155 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 1,000 0,01234594 0,08617464 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,01234594 0,08592912 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,01234594 0,08568501 ! hexose transport GO:0008645 68 44 1,000 0,01290102 0,08928381 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 1,000 0,01290102 0,0890316 ! double-strand break repair GO:0006302 85 44 1,000 0,01290102 0,0887808 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,01346681 0,09241412 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,01346681 0,09215526 ! B cell differentiation GO:0030183 124 45 1,000 0,01346681 0,09189784 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,01404324 0,09556443 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01404324 0,09529897 ! cell growth GO:0016049 90 46 1,000 0,01404324 0,09503499 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,0146302 0,09873362 ! response to insulin stimulus GO:0032868 98 47 1,000 0,0146302 0,09846163 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,0152276 0,10220063 ! mitochondrial transport GO:0006839 94 48 1,000 0,0152276 0,10192063 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,0152276 0,10164216 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,0152276 0,1013652 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,0152276 0,10108975 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,01583536 0,10483953 ! JNK cascade GO:0007254 106 49 1,000 0,01583536 0,10455618 ! regulation of action potential GO:0001508 102 50 1,000 0,01645339 0,10834401 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,01645339 0,10805276 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,01645339 0,10776308 GO:0019724|B cell mediated immunity, ! epidermal cell differentiation GO:0009913 87 50 1,000 0,01645339 0,10747494 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,01708159 0,11128089 ! peptide metabolic process GO:0006518 80 51 1,000 0,01708159 0,11098493 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,01708159 0,11069054 ! positive regulation of binding GO:0051099 88 52 1,000 0,01771989 0,114523 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,01836819 0,11839971 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,01836819 0,11808813 ! synapse organization GO:0050808 102 53 1,000 0,01836819 0,11777819 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,01902641 0,12167935 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01940198 0,12375727 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01940198 0,12343498 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01940198 0,12311437 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01940198 0,12279542 ! neuron fate determination GO:0048664 7 5 0,000 0,01940198 0,12247812 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01940198 0,12216246 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01940198 0,12184841 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01940198 0,12153598 ! polyol transport GO:0015791 12 5 0,000 0,01940198 0,12122515 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01940198 0,1209159 ! response to superoxide GO:0000303 10 5 0,000 0,01940198 0,12060823 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01940198 0,12030211 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01940198 0,11999755 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01940198 0,11969453 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01940198 0,11939303 ! female meiosis GO:0007143 10 5 0,000 0,01940198 0,11909305 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01940198 0,11879457 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01940198 0,11849758 ! hypothalamus development GO:0021854 9 5 0,000 0,01940198 0,11820208 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01940198 0,11790804 ! cobalt ion transport GO:0006824 11 5 0,000 0,01940198 0,11761547 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01940198 0,11732434 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01940198 0,11703465 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01940198 0,11674639 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01940198 0,11645954 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01940198 0,1161741 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01940198 0,11589006 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01940198 0,1156074 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01940198 0,11532611 ! transposition GO:0032196 9 5 0,000 0,01940198 0,1150462 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01940198 0,11476763 ! negative chemotaxis GO:0050919 16 5 0,000 0,01940198 0,11449042 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01940198 0,11421454 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01940198 0,11393998 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01940198 0,11366675 ! behavioral response to pain GO:0048266 10 5 0,000 0,01940198 0,11339482 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01940198 0,11312418 ! Notch receptor processing GO:0007220 11 5 0,000 0,01940198 0,11285484 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01940198 0,11258678 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01940198 0,11231998 ! micturition GO:0060073 9 5 0,000 0,01940198 0,11205445 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01940198 0,11179017 ! copulation GO:0007620 9 5 0,000 0,01940198 0,11152714 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01940198 0,11126534 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01940198 0,11100476 ! bioluminescence GO:0008218 9 5 0,000 0,01940198 0,1107454 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01940198 0,11048726 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01940198 0,11023031 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01940198 0,10997455 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01940198 0,10971998 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01940198 0,10946659 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01940198 0,10921436 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01940198 0,10896329 ! grooming behavior GO:0007625 6 5 0,000 0,01940198 0,10871338 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01940198 0,10846461 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01940198 0,10821697 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01940198 0,10797046 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01940198 0,10772508 ! response to protozoan GO:0001562 13 5 0,000 0,01940198 0,1074808 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01940198 0,10723763 ! lymph vessel development GO:0001945 10 5 0,000 0,01940198 0,10699556 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01940198 0,10675458 ! endochondral ossification GO:0001958 17 5 0,000 0,01940198 0,10651468 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01940198 0,10627586 ! single strand break repair GO:0000012 8 5 0,000 0,01940198 0,10603811 ! parathyroid gland development GO:0060017 14 5 0,000 0,01940198 0,10580141 ! anagen GO:0042640 7 5 0,000 0,01940198 0,10556578 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01940198 0,10533118 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01940198 0,10509763 ! cytokine secretion GO:0050663 15 5 0,000 0,01940198 0,10486512 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01940198 0,10463363 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01940198 0,10440316 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01940198 0,1041737 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01940198 0,10394525 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01940198 0,1037178 GO:0046516|hypusine metabolic process, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01940198 0,10349134 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01940198 0,10326587 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01940198 0,10304138 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01940198 0,10281786 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01940198 0,10259531 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01940198 0,10237372 ! microvillus organization GO:0032528 8 5 0,000 0,01940198 0,10215309 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01940198 0,1019334 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01940198 0,10171466 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01940198 0,10149686 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01940198 0,10127999 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01940198 0,10106404 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01940198 0,10084901 ! polyol catabolic process GO:0046174 9 5 0,000 0,01940198 0,10063489 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01940198 0,10042168 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01940198 0,10020937 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01940198 0,09999796 ! muscle cell migration GO:0014812 8 5 0,000 0,01940198 0,09978744 ! mitochondrial fission GO:0000266 8 5 0,000 0,01940198 0,0995778 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01940198 0,09936904 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01940198 0,09916116 ! mRNA transcription GO:0009299 10 5 0,000 0,01940198 0,09895414 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01940198 0,09874799 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01940198 0,09854269 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01940198 0,09833824 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01940198 0,09813464 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01940198 0,09793189 ! monocyte activation GO:0042117 10 5 0,000 0,01940198 0,09772997 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01940198 0,09752887 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01940198 0,09732861 ! response to food GO:0032094 6 5 0,000 0,01940198 0,09712917 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01940198 0,09693054 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01940198 0,09673272 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01940198 0,09653571 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01940198 0,0963395 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01940198 0,09614408 ! forebrain neuron development GO:0021884 13 5 0,000 0,01940198 0,09594946 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01940198 0,09575562 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01940198 0,09556257 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01940198 0,09537029 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01940198 0,09517878 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01940198 0,09498804 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01940198 0,09479807 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01940198 0,09460885 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01940198 0,09442038 ! lipid glycosylation GO:0030259 7 5 0,000 0,01940198 0,09423267 ! nucleobase transport GO:0015851 6 5 0,000 0,01940198 0,0940457 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01940198 0,09385947 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01940198 0,09367398 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01940198 0,09348922 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01940198 0,09330518 ! basic amino acid transport GO:0015802 12 5 0,000 0,01940198 0,09312187 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01940198 0,09293928 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01940198 0,0927574 ! actin nucleation GO:0045010 11 5 0,000 0,01940198 0,09257624 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01940198 0,09239578 ! depurination GO:0045007 5 5 0,000 0,01940198 0,09221602 ! depyrimidination GO:0045008 10 5 0,000 0,01940198 0,09203696 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01940198 0,09185859 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01940198 0,09168092 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01940198 0,09150393 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01940198 0,09132762 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01940198 0,09115199 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01940198 0,09097703 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01940198 0,09080275 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01940198 0,09062913 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01940198 0,09045617 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01940198 0,09028387 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01940198 0,09011223 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01940198 0,08994124 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01940198 0,0897709 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01940198 0,0896012 ! response to arsenic GO:0046685 11 5 0,000 0,01940198 0,08943214 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01940198 0,08926372 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01940198 0,08909593 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01940198 0,08892877 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01940198 0,08876223 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01940198 0,08859632 ! response to mercury ion GO:0046689 8 5 0,000 0,01940198 0,08843103 ! response to cadmium ion GO:0046686 7 5 0,000 0,01940198 0,08826636 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01940198 0,08810229 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01940198 0,08793884 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01940198 0,08777599 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01940198 0,08761374 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01940198 0,08745209 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01940198 0,08729104 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01940198 0,08713058 ! decidualization GO:0046697 11 5 0,000 0,01940198 0,0869707 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01940198 0,08681142 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01940198 0,08665271 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01940198 0,08649459 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01940198 0,08633704 ! embryonic cleavage GO:0040016 6 5 0,000 0,01940198 0,08618006 ! peroxisome fission GO:0016559 5 5 0,000 0,01940198 0,08602365 ! histone demethylation GO:0016577 13 5 0,000 0,01940198 0,08586781 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01940198 0,08571254 ! mitotic recombination GO:0006312 9 5 0,000 0,01940198 0,08555782 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01940198 0,08540366 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01940198 0,08525006 ! metaphase plate congression GO:0051310 7 5 0,000 0,01940198 0,08509701 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01940198 0,0849445 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01940198 0,08479255 ! enteric nervous system development GO:0048484 8 5 0,000 0,01940198 0,08464113 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01940198 0,08449026 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01940198 0,08433992 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01940198 0,08419011 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01940198 0,08404084 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01940198 0,08389209 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01940198 0,08374387 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01940198 0,08359618 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01940198 0,083449 ! metaphase GO:0051323 11 5 0,000 0,01940198 0,08330234 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01940198 0,0831562 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01940198 0,08301057 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01940198 0,08286544 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01940198 0,08272083 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01940198 0,08257671 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01940198 0,0824331 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01940198 0,08228999 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01940198 0,08214737 ! response to redox state GO:0051775 6 5 0,000 0,01940198 0,08200525 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01940198 0,08186362 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01940198 0,08172247 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01940198 0,08158181 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01940198 0,08144164 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01940198 0,08130194 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01940198 0,08116273 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01940198 0,08102399 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01940198 0,08088572 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01940198 0,08074793 ! striatum development GO:0021756 14 5 0,000 0,01940198 0,0806106 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01940198 0,08047374 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01940198 0,08033734 ! glial cell migration GO:0008347 10 5 0,000 0,01940198 0,08020141 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01940198 0,08006593 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01940198 0,07993092 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01940198 0,07979635 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01940198 0,07966224 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01940198 0,07952858 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01940198 0,07939537 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01940198 0,0792626 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01940198 0,07913027 ! neuroprotection GO:0043526 8 5 0,000 0,01940198 0,07899839 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01940198 0,07886694 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01940198 0,07873594 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01940198 0,07860536 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01940198 0,07847522 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01940198 0,07834551 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01940198 0,07821623 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01940198 0,07808737 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01940198 0,07795894 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01940198 0,07783092 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01940198 0,07770333 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01940198 0,07757616 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01940198 0,0774494 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01940198 0,07732306 ! spindle assembly GO:0051225 6 5 0,000 0,01940198 0,07719712 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01940198 0,0770716 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01940198 0,07694648 ! protein palmitoylation GO:0018345 12 5 0,000 0,01940198 0,07682177 ! drug metabolic process GO:0017144 7 5 0,000 0,01940198 0,07669746 ! phospholipid scrambling GO:0017121 8 5 0,000 0,01940198 0,07657356 ! organ regeneration GO:0031100 7 5 0,000 0,01940198 0,07645005 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01940198 0,07632695 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01940198 0,07620423 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,01969445 0,07722882 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,02037225 0,07975865 ! muscle fiber development GO:0048747 131 57 1,000 0,0210597 0,08231814 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,0210597 0,08218665 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,02175672 0,08477141 ! establishment of organelle localization GO:0051656 122 59 1,000 0,02246324 0,08738486 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02323729 0,0902523 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02323729 0,09010905 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02323729 0,08996624 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02323729 0,08982389 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02323729 0,08968199 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02323729 0,08954053 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02323729 0,08939953 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02323729 0,08925896 ! response to oxygen radical GO:0000305 11 6 0,000 0,02323729 0,08911884 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02323729 0,08897915 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02323729 0,0888399 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02323729 0,08870109 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02323729 0,08856271 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02323729 0,08842476 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02323729 0,08828724 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02323729 0,08815015 ! forebrain regionalization GO:0021871 9 6 0,000 0,02323729 0,08801349 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02323729 0,08787724 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02323729 0,08774142 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02323729 0,08760602 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02323729 0,08747103 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02323729 0,08733646 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02323729 0,0872023 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02323729 0,08706856 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02323729 0,08693522 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02323729 0,08680229 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02323729 0,08666977 ! malate metabolic process GO:0006108 13 6 0,000 0,02323729 0,08653765 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02323729 0,08640593 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02323729 0,08627462 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02323729 0,0861437 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02323729 0,08601318 ! protein refolding GO:0042026 15 6 0,000 0,02323729 0,08588305 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02323729 0,08575332 ! opsonization GO:0008228 8 6 0,000 0,02323729 0,08562398 ! mating behavior GO:0007617 7 6 0,000 0,02323729 0,08549503 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02323729 0,08536646 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02323729 0,08523829 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02323729 0,08511049 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02323729 0,08498308 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02323729 0,08485605 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02323729 0,0847294 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02323729 0,08460313 ! toxin metabolic process GO:0009404 11 6 0,000 0,02323729 0,08447723 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02323729 0,08435171 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02323729 0,08422656 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02323729 0,08410178 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02323729 0,08397736 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02323729 0,08385332 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02323729 0,08372964 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02323729 0,08360633 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02323729 0,08348338 ! thymic T cell selection GO:0045061 16 6 0,000 0,02323729 0,08336079 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02323729 0,08323856 ! protein lipoylation GO:0009249 10 6 0,000 0,02323729 0,08311669 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02323729 0,08299517 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02323729 0,08287401 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02323729 0,0827532 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02323729 0,08263275 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02323729 0,08251264 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02323729 0,08239289 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02323729 0,08227348 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02323729 0,08215441 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02323729 0,08203569 ! hyperosmotic response GO:0006972 10 6 0,000 0,02323729 0,08191731 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02323729 0,08179928 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02323729 0,08168158 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02323729 0,08156422 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02323729 0,0814472 ! urea metabolic process GO:0019627 7 6 0,000 0,02323729 0,08133051 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02323729 0,08121416 ! neutrophil activation GO:0042119 7 6 0,000 0,02323729 0,08109814 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02323729 0,08098245 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02323729 0,08086709 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02323729 0,08075206 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02323729 0,08063736 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02323729 0,08052298 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02323729 0,08040892 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02323729 0,08029519 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02323729 0,08018178 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02323729 0,08006869 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02323729 0,07995591 ! carnitine transport GO:0015879 10 6 0,000 0,02323729 0,07984346 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02323729 0,07973132 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02323729 0,07961949 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02323729 0,07950798 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02323729 0,07939678 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02323729 0,07928589 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02323729 0,07917531 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02323729 0,07906504 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02323729 0,07895507 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02323729 0,07884541 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02323729 0,07873606 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02323729 0,07862701 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02323729 0,07851826 ! response to UV-C GO:0010225 14 6 0,000 0,02323729 0,0784098 ! astrocyte development GO:0014002 16 6 0,000 0,02323729 0,07830165 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02323729 0,0781938 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02323729 0,07808624 ! interaction with symbiont GO:0051702 14 6 0,000 0,02323729 0,07797898 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02323729 0,07787201 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02323729 0,07776534 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02323729 0,07765896 ! response to copper ion GO:0046688 10 6 0,000 0,02323729 0,07755287 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02323729 0,07744706 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02323729 0,07734155 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02323729 0,07723632 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02323729 0,07713138 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02323729 0,07702673 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02323729 0,07692236 ! hair follicle maturation GO:0048820 8 6 0,000 0,02323729 0,07681827 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02323729 0,07671446 ! Schwann cell development GO:0014044 15 6 0,000 0,02323729 0,07661093 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02323729 0,07650768 ! response to pheromone GO:0019236 6 6 0,000 0,02323729 0,07640471 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02323729 0,07630201 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02323729 0,0761996 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02323729 0,07609745 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02323729 0,07599558 ! subpallium development GO:0021544 15 6 0,000 0,02323729 0,07589398 ! neural tube patterning GO:0021532 8 6 0,000 0,02323729 0,07579265 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02323729 0,0756916 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02323729 0,07559081 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02323729 0,07549029 ! G2 phase GO:0051319 16 6 0,000 0,02323729 0,07539004 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02323729 0,07529005 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02323729 0,07519033 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02323729 0,07509087 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02323729 0,07499168 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02323729 0,07489274 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02323729 0,07479407 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02323729 0,07469566 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02323729 0,0745975 ! receptor internalization GO:0031623 11 6 0,000 0,02323729 0,0744996 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02323729 0,07440196 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02323729 0,07430458 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02323729 0,07420745 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02323729 0,07411057 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02323729 0,07401395 ! protein deubiquitination GO:0016579 16 6 0,000 0,02323729 0,07391758 ! protein destabilization GO:0031648 9 6 0,000 0,02323729 0,07382145 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02323729 0,07372558 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02323729 0,07362996 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02323729 0,07353458 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02323729 0,07343945 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02323729 0,07334457 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02323729 0,07324993 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02323729 0,07315554 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02323729 0,07306139 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02323729 0,07296748 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02323729 0,07287381 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02323729 0,07278038 ! neural plate development GO:0001840 9 6 0,000 0,02323729 0,07268719 ! catecholamine transport GO:0051937 9 6 0,000 0,02323729 0,07259424 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02323729 0,07250153 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02323729 0,07240905 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02323729 0,07231681 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02323729 0,07222481 ! maternal placenta development GO:0001893 12 6 0,000 0,02323729 0,07213303 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02323729 0,0720415 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02323729 0,07195019 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02323729 0,07185911 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02323729 0,07176827 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02323729 0,07167765 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02323729 0,07158726 GO:0055081|anion homeostasis, ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,02390441 0,07354971 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,02463889 0,07571423 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,02538254 0,07790143 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,02538254 0,07780369 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,02613526 0,08001057 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,02689698 0,08223944 ! tRNA transcription GO:0009304 17 7 0,000 0,02705771 0,08262747 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02705771 0,08252432 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02705771 0,08242142 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02705771 0,08231878 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02705771 0,08221639 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02705771 0,08211426 ! sleep GO:0030431 16 7 0,000 0,02705771 0,08201238 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02705771 0,08191076 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02705771 0,08180938 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02705771 0,08170826 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02705771 0,08160738 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02705771 0,08150676 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02705771 0,08140638 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02705771 0,08130625 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02705771 0,08120636 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02705771 0,08110672 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02705771 0,08100733 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02705771 0,08090818 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02705771 0,08080927 ! glycolipid transport GO:0046836 11 7 0,000 0,02705771 0,0807106 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02705771 0,08061217 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02705771 0,08051398 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,02705771 0,08041603 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02705771 0,08031832 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02705771 0,08022085 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02705771 0,08012361 ! mRNA stabilization GO:0048255 18 7 0,000 0,02705771 0,08002661 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02705771 0,07992984 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02705771 0,07983331 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02705771 0,07973701 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02705771 0,07964094 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02705771 0,0795451 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02705771 0,07944949 ! lipoprotein transport GO:0042953 14 7 0,000 0,02705771 0,07935412 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02705771 0,07925897 ! rhythmic behavior GO:0007622 17 7 0,000 0,02705771 0,07916405 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02705771 0,07906935 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02705771 0,07897489 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02705771 0,07888064 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02705771 0,07878663 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02705771 0,07869283 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02705771 0,07859926 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02705771 0,07850591 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02705771 0,07841279 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02705771 0,07831988 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02705771 0,07822719 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02705771 0,07813473 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02705771 0,07804248 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02705771 0,07795045 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02705771 0,07785863 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02705771 0,07776704 ! spinal cord patterning GO:0021511 14 7 0,000 0,02705771 0,07767565 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02705771 0,07758448 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02705771 0,07749353 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02705771 0,07740279 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02705771 0,07731226 ! adrenal gland development GO:0030325 17 7 0,000 0,02705771 0,07722194 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02705771 0,07713183 ! ovulation GO:0030728 10 7 0,000 0,02705771 0,07704193 ! adenohypophysis development GO:0021984 11 7 0,000 0,02705771 0,07695225 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02705771 0,07686277 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02705771 0,0767735 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02705771 0,07668443 ! microtubule nucleation GO:0007020 21 7 0,000 0,02705771 0,07659557 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02705771 0,07650692 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02705771 0,07641847 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02705771 0,07633023 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02705771 0,07624219 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02705771 0,07615435 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02705771 0,07606672 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02705771 0,07597929 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02705771 0,07589205 ! galactose metabolic process GO:0006012 13 7 0,000 0,02705771 0,07580502 ! vesicle fusion GO:0006906 20 7 0,000 0,02705771 0,07571819 ! response to dietary excess GO:0002021 8 7 0,000 0,02705771 0,07563156 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02705771 0,07554512 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02705771 0,07545888 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02705771 0,07537284 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02705771 0,07528699 ! nucleoside transport GO:0015858 11 7 0,000 0,02705771 0,07520134 ! nucleoside salvage GO:0043174 11 7 0,000 0,02705771 0,07511589 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02705771 0,07503062 ! male sex determination GO:0030238 15 7 0,000 0,02705771 0,07494556 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02705771 0,07486068 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! parturition GO:0007567 16 7 0,000 0,02705771 0,074776 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02705771 0,0746915 ! rRNA modification GO:0000154 14 7 0,000 0,02705771 0,0746072 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02705771 0,07452309 ! spindle checkpoint GO:0031577 16 7 0,000 0,02705771 0,07443917 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02705771 0,07435543 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02705771 0,07427189 ! monocyte differentiation GO:0030224 16 7 0,000 0,02705771 0,07418853 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02705771 0,07410536 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02705771 0,07402237 ! fibrinolysis GO:0042730 11 7 0,000 0,02705771 0,07393957 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02705771 0,07385696 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02705771 0,07377453 ! eating behavior GO:0042755 8 7 0,000 0,02705771 0,07369229 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02705771 0,07361022 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02705771 0,07352834 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02705771 0,07344664 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02705771 0,07336513 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02705771 0,07328379 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02705771 0,07320264 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02705771 0,07312166 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02705771 0,07304086 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02705771 0,07296024 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02705771 0,0728798 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02705771 0,07279954 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02705771 0,07271945 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02705771 0,07263954 ! histone ubiquitination GO:0016574 9 7 0,000 0,02705771 0,0725598 ! regulation of meiosis GO:0040020 12 7 0,000 0,02705771 0,07248024 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02705771 0,07240085 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02705771 0,07232164 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02705771 0,0722426 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02705771 0,07216373 ! transcription termination GO:0006353 14 7 0,000 0,02705771 0,07208504 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02705771 0,07200651 ! anaphase GO:0051322 18 7 0,000 0,02705771 0,07192816 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02705771 0,07184998 ! axonal fasciculation GO:0007413 19 7 0,000 0,02705771 0,07177197 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02705771 0,07169412 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02705771 0,07161645 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02705771 0,07153894 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02705771 0,0714616 ! diuresis GO:0030146 12 7 0,000 0,02705771 0,07138443 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02705771 0,07130742 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02705771 0,07123058 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02705771 0,07115391 ! antibiotic transport GO:0042891 9 7 0,000 0,02705771 0,0710774 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02705771 0,07100105 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02705771 0,07092487 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02705771 0,07084885 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02705771 0,070773 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02705771 0,0706973 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02705771 0,07062177 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02705771 0,0705464 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02705771 0,07047119 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02705771 0,07039614 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02705771 0,07032126 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02705771 0,07024652 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02705771 0,07017195 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02705771 0,07009754 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02705771 0,07002328 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02705771 0,06994918 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02705771 0,06987524 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02705771 0,06980146 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02705771 0,06972783 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02705771 0,06965435 ! muscle adaptation GO:0043500 13 7 0,000 0,02705771 0,06958103 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02705771 0,06950787 ! retina homeostasis GO:0001895 12 7 0,000 0,02705771 0,06943485 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02705771 0,06936199 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02705771 0,06928929 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02705771 0,06921673 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02705771 0,06914433 ! ear development GO:0043583 114 66 1,000 0,02766761 0,07062901 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,02766761 0,07055529 ! gonad development GO:0008406 115 66 1,000 0,02766761 0,07048171 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,02766761 0,0704083 ! chromosome segregation GO:0007059 127 67 1,000 0,02844707 0,07231654 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,02844707 0,07224137 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,02923529 0,07416596 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,02923529 0,07408902 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,02923529 0,07401225 ! adaptive immune response GO:0002250 126 68 1,000 0,02923529 0,07393563 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,02923529 0,07385917 ! lung development GO:0030324 165 69 1,000 0,03003219 0,07579404 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,03003219 0,07571582 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,03003219 0,07563777 ! germ cell development GO:0007281 133 70 1,000 0,03083768 0,07758645 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03086329 0,07757101 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03086329 0,07749128 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,03086329 0,07741172 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03086329 0,07733233 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03086329 0,07725309 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03086329 0,07717402 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03086329 0,07709511 ! male meiosis GO:0007140 9 8 0,000 0,03086329 0,07701636 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03086329 0,07693777 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03086329 0,07685934 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03086329 0,07678108 ! meiotic prophase I GO:0007128 14 8 0,000 0,03086329 0,07670297 ! response to zinc ion GO:0010043 12 8 0,000 0,03086329 0,07662502 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03086329 0,07654723 ! oligopeptide transport GO:0006857 16 8 0,000 0,03086329 0,07646959 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03086329 0,07639211 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03086329 0,07631479 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03086329 0,07623763 ! signal peptide processing GO:0006465 12 8 0,000 0,03086329 0,07616062 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03086329 0,07608377 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03086329 0,07600707 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03086329 0,07593053 ! succinate metabolic process GO:0006105 17 8 0,000 0,03086329 0,07585414 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03086329 0,07577791 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03086329 0,07570182 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03086329 0,0756259 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03086329 0,07555012 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03086329 0,07547449 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03086329 0,07539902 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03086329 0,07532369 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03086329 0,07524852 ! reflex GO:0060004 17 8 0,000 0,03086329 0,0751735 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03086329 0,07509862 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03086329 0,0750239 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03086329 0,07494932 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03086329 0,07487489 ! pigment granule organization GO:0048753 17 8 0,000 0,03086329 0,07480061 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03086329 0,07472648 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03086329 0,07465249 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03086329 0,07457865 ! histidine catabolic process GO:0006548 10 8 0,000 0,03086329 0,07450496 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03086329 0,07443141 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03086329 0,07435801 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03086329 0,07428475 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03086329 0,07421163 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03086329 0,07413866 ! melanin metabolic process GO:0006582 17 8 0,000 0,03086329 0,07406583 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03086329 0,07399315 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03086329 0,07392061 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03086329 0,07384821 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03086329 0,07377595 ! macrophage activation GO:0042116 13 8 0,000 0,03086329 0,07370383 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03086329 0,07363185 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03086329 0,07356002 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03086329 0,07348832 ! purine salvage GO:0043101 12 8 0,000 0,03086329 0,07341676 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03086329 0,07334535 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03086329 0,07327407 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03086329 0,07320293 ! osteoblast development GO:0002076 17 8 0,000 0,03086329 0,07313193 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03086329 0,07306106 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03086329 0,07299034 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03086329 0,07291975 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03086329 0,07284929 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03086329 0,07277897 ! response to UV-B GO:0010224 17 8 0,000 0,03086329 0,07270879 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03086329 0,07263875 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03086329 0,07256883 ! intermediate filament organization GO:0045109 12 8 0,000 0,03086329 0,07249906 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03086329 0,07242941 ! cellular extravasation GO:0045123 13 8 0,000 0,03086329 0,0723599 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03086329 0,07229052 ! response to antibiotic GO:0046677 11 8 0,000 0,03086329 0,07222128 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03086329 0,07215217 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03086329 0,07208319 ! DNA topological change GO:0006265 12 8 0,000 0,03086329 0,07201434 ! response to tropane GO:0014073 15 8 0,000 0,03086329 0,07194563 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03086329 0,07187704 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03086329 0,07180859 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03086329 0,07174026 ! mast cell activation GO:0045576 14 8 0,000 0,03086329 0,07167207 ! gas homeostasis GO:0033483 14 8 0,000 0,03086329 0,07160401 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03086329 0,07153607 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03086329 0,07146826 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03086329 0,07140058 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03086329 0,07133303 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03086329 0,07126561 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03086329 0,07119832 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03086329 0,07113115 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03086329 0,07106411 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03086329 0,07099719 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03086329 0,0709304 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03086329 0,07086374 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03086329 0,0707972 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03086329 0,07073079 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03086329 0,0706645 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03086329 0,07059833 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03086329 0,07053229 ! hormone catabolic process GO:0042447 17 8 0,000 0,03086329 0,07046637 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03086329 0,07040058 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03086329 0,0703349 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03086329 0,07026935 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03086329 0,07020393 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03086329 0,07013862 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03086329 0,07007344 ! adult feeding behavior GO:0008343 10 8 0,000 0,03086329 0,07000837 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03086329 0,06994343 ! ATP catabolic process GO:0006200 11 8 0,000 0,03086329 0,06987861 ! blastocyst growth GO:0001832 19 8 0,000 0,03086329 0,0698139 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03086329 0,06974932 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03086329 0,06968486 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03086329 0,06962051 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03086329 0,06955629 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03086329 0,06949218 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03086329 0,06942819 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03086329 0,06936432 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03086329 0,06930057 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03086329 0,06923693 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03086329 0,06917341 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03086329 0,06911001 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03086329 0,06904672 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03086329 0,06898355 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03086329 0,06892049 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03086329 0,06885755 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03086329 0,06879472 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03086329 0,06873201 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03086329 0,06866941 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03086329 0,06860693 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,03165169 0,07029552 ! carbohydrate transport GO:0008643 114 72 1,000 0,03247414 0,0720566 ! respiratory tube development GO:0030323 171 72 1,000 0,03247414 0,07199121 ! actin filament organization GO:0007015 167 72 1,000 0,03247414 0,07192594 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,03247414 0,07186079 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,03247414 0,07179576 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,03247414 0,07173085 ! respiratory system development GO:0060541 175 74 1,000 0,03414405 0,07535131 ! organelle localization GO:0051640 155 74 1,000 0,03414405 0,07528331 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03465409 0,076339 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03465409 0,07627023 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03465409 0,07620158 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03465409 0,07613305 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03465409 0,07606465 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03465409 0,07599637 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03465409 0,07592821 ! reproductive behavior GO:0019098 22 9 0,000 0,03465409 0,07586017 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03465409 0,07579226 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03465409 0,07572446 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03465409 0,07565679 ! UTP metabolic process GO:0046051 10 9 0,000 0,03465409 0,07558924 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03465409 0,07552181 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,03465409 0,0754545 ! artery development GO:0060840 25 9 0,000 0,03465409 0,07538731 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03465409 0,07532024 ! regulation of glycolysis GO:0006110 20 9 0,000 0,03465409 0,07525329 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03465409 0,07518646 ! equilibrioception GO:0050957 20 9 0,000 0,03465409 0,07511974 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03465409 0,07505315 ! chemosensory behavior GO:0007635 21 9 0,000 0,03465409 0,07498667 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03465409 0,07492031 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03465409 0,07485407 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03465409 0,07478794 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03465409 0,07472193 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03465409 0,07465604 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03465409 0,07459027 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03465409 0,0745246 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03465409 0,07445906 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03465409 0,07439363 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03465409 0,07432832 ! protein targeting to ER GO:0045047 25 9 0,000 0,03465409 0,07426311 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03465409 0,07419803 ! T cell selection GO:0045058 27 9 0,000 0,03465409 0,07413306 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,03465409 0,0740682 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03465409 0,07400345 ! glycine catabolic process GO:0006546 15 9 0,000 0,03465409 0,07393882 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03465409 0,0738743 ! endosome organization GO:0007032 20 9 0,000 0,03465409 0,0738099 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03465409 0,0737456 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03465409 0,07368142 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03465409 0,07361735 ! mannose metabolic process GO:0006013 13 9 0,000 0,03465409 0,07355339 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03465409 0,07348954 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03465409 0,0734258 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03465409 0,07336218 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03465409 0,07329866 ! receptor clustering GO:0043113 20 9 0,000 0,03465409 0,07323525 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03465409 0,07317195 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03465409 0,07310877 ! retinol metabolic process GO:0042572 20 9 0,000 0,03465409 0,07304569 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03465409 0,07298272 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03465409 0,07291985 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03465409 0,0728571 ! macrophage differentiation GO:0030225 15 9 0,000 0,03465409 0,07279445 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03465409 0,07273192 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03465409 0,07266949 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03465409 0,07260716 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03465409 0,07254495 ! response to amine stimulus GO:0014075 13 9 0,000 0,03465409 0,07248283 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03465409 0,07242083 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03465409 0,07235893 ! erythrocyte development GO:0048821 17 9 0,000 0,03465409 0,07229714 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03465409 0,07223545 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03465409 0,07217387 ! renal water homeostasis GO:0003091 15 9 0,000 0,03465409 0,07211239 ! postreplication repair GO:0006301 25 9 0,000 0,03465409 0,07205102 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03465409 0,07198975 ! icosanoid secretion GO:0032309 15 9 0,000 0,03465409 0,07192859 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03465409 0,07186753 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03465409 0,07180657 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03465409 0,07174572 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03465409 0,07168497 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03465409 0,07162432 ! sterol catabolic process GO:0016127 14 9 0,000 0,03465409 0,07156378 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03465409 0,07150334 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03465409 0,071443 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03465409 0,07138276 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03465409 0,07132262 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03465409 0,07126258 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03465409 0,07120265 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03465409 0,07114282 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03465409 0,07108308 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03465409 0,07102345 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03465409 0,07096392 ! purine base metabolic process GO:0006144 25 9 0,000 0,03465409 0,07090448 ! pigment granule transport GO:0051904 17 9 0,000 0,03465409 0,07084515 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03465409 0,07078591 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03465409 0,07072678 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03465409 0,07066774 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03465409 0,0706088 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03465409 0,07054996 ! mitochondrion localization GO:0051646 18 9 0,000 0,03465409 0,07049122 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,03499135 0,07111803 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,03499135 0,07105891 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,03584679 0,07273564 ! regulation of blood pressure GO:0008217 134 76 1,000 0,03584679 0,07267528 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,03584679 0,07261502 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,03671029 0,0743026 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03843018 0,0777193 ! regulation of developmental growth GO:0048638 16 10 0,000 0,03843018 0,07765502 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03843018 0,07759084 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03843018 0,07752677 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03843018 0,07746281 ! associative learning GO:0008306 21 10 0,000 0,03843018 0,07739894 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03843018 0,07733519 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03843018 0,07727154 ! phosphate transport GO:0006817 24 10 0,000 0,03843018 0,07720799 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03843018 0,07714455 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03843018 0,07708121 ! CTP metabolic process GO:0046036 11 10 0,000 0,03843018 0,07701798 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03843018 0,07695485 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03843018 0,07689183 ! GTP metabolic process GO:0046039 11 10 0,000 0,03843018 0,0768289 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03843018 0,07676608 GO:0007520|myoblast fusion, ! social behavior GO:0035176 29 10 0,000 0,03843018 0,07670337 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03843018 0,07664075 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03843018 0,07657824 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03843018 0,07651583 ! androgen metabolic process GO:0008209 17 10 0,000 0,03843018 0,07645352 ! phospholipid efflux GO:0033700 19 10 0,000 0,03843018 0,07639131 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03843018 0,0763292 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03843018 0,0762672 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03843018 0,07620529 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03843018 0,07614349 ! lung alveolus development GO:0048286 26 10 0,000 0,03843018 0,07608178 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03843018 0,07602018 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03843018 0,07595867 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03843018 0,07589727 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03843018 0,07583596 ! endoderm development GO:0007492 18 10 0,000 0,03843018 0,07577475 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03843018 0,07571364 ! arginine catabolic process GO:0006527 17 10 0,000 0,03843018 0,07565263 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03843018 0,07559172 ! proline metabolic process GO:0006560 13 10 0,000 0,03843018 0,07553091 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03843018 0,07547019 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03843018 0,07540957 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 34 10 0,000 0,03843018 0,07534905 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03843018 0,07528863 ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03843018 0,0752283 ! B cell proliferation GO:0042100 19 10 0,000 0,03843018 0,07516807 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03843018 0,07510794 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03843018 0,0750479 ! multicellular organism growth GO:0035264 19 10 0,000 0,03843018 0,07498796 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03843018 0,07492811 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03843018 0,07486836 ! ruffle organization GO:0031529 17 10 0,000 0,03843018 0,0748087 ! epithelial cell development GO:0002064 21 10 0,000 0,03843018 0,07474914 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03843018 0,07468967 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03843018 0,0746303 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03843018 0,07457102 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03843018 0,07451184 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03843018 0,07445275 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03843018 0,07439376 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,03843018 0,07433485 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03843018 0,07427604 ! protein heterooligomerization GO:0051291 17 10 0,000 0,03843018 0,07421733 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03843018 0,0741587 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03843018 0,07410017 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03843018 0,07404173 ! segment specification GO:0007379 15 10 0,000 0,03843018 0,07398339 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03843018 0,07392513 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03843018 0,07386697 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03843018 0,0738089 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03843018 0,07375092 ! response to dsRNA GO:0043331 23 10 0,000 0,03843018 0,07369303 ! DNA ligation GO:0006266 18 10 0,000 0,03843018 0,07363523 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03843018 0,07357752 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03843018 0,07351991 ! melanosome localization GO:0032400 16 10 0,000 0,03843018 0,07346238 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03843018 0,07340494 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03843018 0,07334759 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03843018 0,07329034 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03843018 0,07323317 ! induction of an organ GO:0001759 17 10 0,000 0,03843018 0,07317609 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03843018 0,0731191 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03843018 0,07306219 ! protein sumoylation GO:0016925 17 10 0,000 0,03843018 0,07300538 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03843018 0,07294866 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03843018 0,07289202 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03843018 0,07283547 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03843018 0,07277901 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03843018 0,07272263 ! salivary gland development GO:0007431 28 10 0,000 0,03843018 0,07266635 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03843018 0,07261015 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03843018 0,07255403 ! midbrain development GO:0030901 14 10 0,000 0,03843018 0,07249801 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03843018 0,07244207 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03843018 0,07238621 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03843018 0,07233045 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03843018 0,07227477 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03843018 0,07221917 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03843018 0,07216366 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03843018 0,07210823 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03843018 0,07205289 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03843018 0,07199764 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,03843018 0,07194247 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,03843018 0,07188738 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03843018 0,07183238 ! blastocyst formation GO:0001825 18 10 0,000 0,03843018 0,07177746 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03843018 0,07172263 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03843018 0,07166788 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03843018 0,07161321 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03843018 0,07155863 ! response to nicotine GO:0035094 20 10 0,000 0,03843018 0,07150413 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03843018 0,07144971 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03843018 0,07139538 ! protein oligomerization GO:0051259 149 79 1,000 0,03846116 0,07139863 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,03934838 0,07299019 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,03934838 0,07293481 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,03934838 0,07287952 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,04114603 0,07615132 ! response to drug GO:0042493 149 83 1,000 0,04205631 0,07777711 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04219159 0,07796828 ! respiratory burst GO:0045730 17 11 0,000 0,04219159 0,07790934 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04219159 0,0778505 ! neuron fate specification GO:0048665 18 11 0,000 0,04219159 0,07779175 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04219159 0,07773308 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04219159 0,0776745 ! thyroid gland development GO:0030878 26 11 0,000 0,04219159 0,07761601 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,04219159 0,07755761 ! synapsis GO:0007129 14 11 0,000 0,04219159 0,0774993 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04219159 0,07744107 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04219159 0,07738293 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,04219159 0,07732488 ! response to pain GO:0048265 27 11 0,000 0,04219159 0,07726691 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,04219159 0,07720904 ! blood vessel remodeling GO:0001974 30 11 0,000 0,04219159 0,07715124 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,04219159 0,07709354 ! bone resorption GO:0045453 16 11 0,000 0,04219159 0,07703592 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04219159 0,07697839 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,04219159 0,07692094 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04219159 0,07686358 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04219159 0,07680631 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04219159 0,07674912 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04219159 0,07669201 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04219159 0,07663499 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04219159 0,07657806 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04219159 0,0765212 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04219159 0,07646444 ! UV protection GO:0009650 20 11 0,000 0,04219159 0,07640776 ! adult heart development GO:0007512 16 11 0,000 0,04219159 0,07635116 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,04219159 0,07629464 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04219159 0,07623821 ! macroautophagy GO:0016236 19 11 0,000 0,04219159 0,07618186 ! temperature homeostasis GO:0001659 18 11 0,000 0,04219159 0,0761256 ! behavioral fear response GO:0001662 27 11 0,000 0,04219159 0,07606942 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04219159 0,07601332 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04219159 0,0759573 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04219159 0,07590137 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04219159 0,07584552 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,04219159 0,07578975 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04219159 0,07573406 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04219159 0,07567846 ! regulation of organ growth GO:0046620 14 11 0,000 0,04219159 0,07562294 ! pigment granule localization GO:0051875 20 11 0,000 0,04219159 0,07556749 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04219159 0,07551213 ! vasoconstriction GO:0042310 20 11 0,000 0,04219159 0,07545685 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04219159 0,07540166 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04219159 0,07534654 ! embryonic axis specification GO:0000578 19 11 0,000 0,04219159 0,0752915 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04219159 0,07523654 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04219159 0,07518166 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04219159 0,07512687 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04219159 0,07507215 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04219159 0,07501751 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04219159 0,07496295 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04219159 0,07490848 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04219159 0,07485408 ! prophase GO:0051324 17 11 0,000 0,04219159 0,07479976 ! neuroblast proliferation GO:0007405 25 11 0,000 0,04219159 0,07474551 ! nucleosome positioning GO:0016584 15 11 0,000 0,04219159 0,07469135 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04219159 0,07463726 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04219159 0,07458326 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04219159 0,07452933 ! apical protein localization GO:0045176 18 11 0,000 0,04219159 0,07447548 ! acid secretion GO:0046717 20 11 0,000 0,04219159 0,07442171 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04219159 0,07436801 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04219159 0,07431439 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,04219159 0,07426085 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04219159 0,07420739 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04219159 0,074154 ! thymus development GO:0048538 29 11 0,000 0,04219159 0,07410069 ! cholesterol efflux GO:0033344 21 11 0,000 0,04219159 0,07404746 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04219159 0,0739943 ! oocyte development GO:0048599 20 11 0,000 0,04219159 0,07394122 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,04219159 0,07388822 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,04219159 0,07383529 ! embryonic gut development GO:0048566 19 11 0,000 0,04219159 0,07378244 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04219159 0,07372966 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04219159 0,07367696 ! activation of innate immune response GO:0002218 16 11 0,000 0,04219159 0,07362433 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04219159 0,07357178 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04219159 0,0735193 ! lysogeny GO:0030069 22 11 0,000 0,04219159 0,0734669 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04219159 0,07341457 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04219159 0,07336232 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04219159 0,07331014 ! regulation of embryonic development GO:0045995 35 11 0,000 0,04219159 0,07325804 ! nucleus localization GO:0051647 22 11 0,000 0,04219159 0,07320601 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0459384 0,07965047 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0459384 0,07959398 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,0459384 0,07953757 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0459384 0,07948124 ! virus-host interaction GO:0019048 30 12 0,000 0,0459384 0,07942499 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,0459384 0,07936882 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0459384 0,07931273 ! protein complex disassembly GO:0043241 28 12 0,000 0,0459384 0,07925672 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0459384 0,07920079 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0459384 0,07914493 ! hippocampus development GO:0021766 29 12 0,000 0,0459384 0,07908916 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0459384 0,07903346 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0459384 0,07897784 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0459384 0,0789223 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0459384 0,07886684 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0459384 0,07881146 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0459384 0,07875615 ! drug transport GO:0015893 16 12 0,000 0,0459384 0,07870092 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0459384 0,07864577 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0459384 0,0785907 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0459384 0,0785357 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0459384 0,07848078 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0459384 0,07842594 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0459384 0,07837117 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0459384 0,07831648 ! lipid digestion GO:0044241 21 12 0,000 0,0459384 0,07826187 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0459384 0,07820733 ! entry into host cell GO:0030260 34 12 0,000 0,0459384 0,07815287 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0459384 0,07809848 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0459384 0,07804417 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0459384 0,07798994 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0459384 0,07793578 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0459384 0,07788169 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0459384 0,07782768 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0459384 0,07777375 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0459384 0,07771989 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0459384 0,0776661 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0459384 0,07761239 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0459384 0,07755875 ! cranial nerve development GO:0021545 23 12 0,000 0,0459384 0,07750519 ! fucose catabolic process GO:0019317 25 12 0,000 0,0459384 0,0774517 GO:0042355|L-fucose catabolic process, ! histone acetylation GO:0016573 27 12 0,000 0,0459384 0,07739829 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0459384 0,07734495 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0459384 0,07729168 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0459384 0,07723848 ! zymogen activation GO:0031638 18 12 0,000 0,0459384 0,07718536 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0459384 0,07713231 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0459384 0,07707934 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0459384 0,07702644 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0459384 0,07697361 ! oocyte differentiation GO:0009994 21 12 0,000 0,0459384 0,07692085 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0459384 0,07686816 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0459384 0,07681555 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0459384 0,07676301 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0459384 0,07671054 ! defense response to fungus GO:0050832 15 12 0,000 0,0459384 0,07665814 ! developmental induction GO:0031128 22 12 0,000 0,0459384 0,07660581 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0459384 0,07655356 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0459384 0,07650138 ! response to cold GO:0009409 17 12 0,000 0,0459384 0,07644926 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0459384 0,07639722 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0459384 0,07634525 ! localization within membrane GO:0051668 26 12 0,000 0,0459384 0,07629335 ! amine biosynthetic process GO:0009309 146 88 1,000 0,0467194 0,0775377 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,04967066 0,08237978 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04967066 0,0823239 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04967066 0,08226808 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04967066 0,08221235 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04967066 0,08215668 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04967066 0,0821011 ! peroxisomal transport GO:0043574 28 13 0,000 0,04967066 0,08204559 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04967066 0,08199015 ! cartilage condensation GO:0001502 22 13 0,000 0,04967066 0,08193479 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04967066 0,0818795 ! organelle fusion GO:0048284 36 13 0,000 0,04967066 0,08182429 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04967066 0,08176915 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,04967066 0,08171409 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04967066 0,0816591 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04967066 0,08160418 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,04967066 0,08154934 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04967066 0,08149457 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04967066 0,08143988 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,04967066 0,08138526 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04967066 0,08133071 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04967066 0,08127624 ! methionine metabolic process GO:0006555 31 13 0,000 0,04967066 0,08122183 ! plasma membrane organization GO:0007009 27 13 0,000 0,04967066 0,08116751 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04967066 0,08111325 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04967066 0,08105907 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04967066 0,08100495 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,04967066 0,08095091 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,04967066 0,08089695 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,04967066 0,08084305 ! exocrine system development GO:0035272 34 13 0,000 0,04967066 0,08078923 ! asymmetric protein localization GO:0008105 24 13 0,000 0,04967066 0,08073548 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,04967066 0,0806818 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,04967066 0,08062819 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,04967066 0,08057465 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,04967066 0,08052118 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,04967066 0,08046779 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04967066 0,08041446 ! protein homotetramerization GO:0051289 24 13 0,000 0,04967066 0,08036121 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04967066 0,08030802 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04967066 0,08025491 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,04967066 0,08020186 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,04967066 0,08014889 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04967066 0,08009599 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04967066 0,08004315 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,04967066 0,07999039 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04967066 0,0799377 ! histone methylation GO:0016571 29 13 0,000 0,04967066 0,07988507 ! chromatin silencing GO:0006342 29 13 0,000 0,04967066 0,07983251 ! gland morphogenesis GO:0022612 31 13 0,000 0,04967066 0,07978003 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04967066 0,07972761 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,04967066 0,07967526 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04967066 0,07962298 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,04967066 0,07957077 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,04967066 0,07951862 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,04967066 0,07946655 ! spleen development GO:0048536 24 13 0,000 0,04967066 0,07941454 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,04967066 0,0793626 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,04967066 0,07931073 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,04967066 0,07925893 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04967066 0,07920719 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04967066 0,07915553 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04967066 0,07910393 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04967066 0,07905239 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04967066 0,07900093 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04967066 0,07894953 ! insulin secretion GO:0030073 24 13 0,000 0,04967066 0,07889819 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04967066 0,07884693 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,04967066 0,07879573 ! acrosome reaction GO:0007340 19 13 0,000 0,04967066 0,0787446 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04967066 0,07869353 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,04967066 0,07864253 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,05156216 0,08158443 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 179 94 1,000 0,05255151 0,08309602 ! rRNA transcription GO:0009303 28 14 0,000 0,05338842 0,08436476 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05338842 0,08431022 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05338842 0,08425576 ! water transport GO:0006833 21 14 0,000 0,05338842 0,08420136 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05338842 0,08414704 ! non-recombinational repair GO:0000726 29 14 0,000 0,05338842 0,08409279 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05338842 0,0840386 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05338842 0,08398449 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,05338842 0,08393045 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05338842 0,08387647 ! lipid localization GO:0010876 32 14 0,000 0,05338842 0,08382257 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05338842 0,08376873 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,05338842 0,08371496 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05338842 0,08366127 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05338842 0,08360764 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05338842 0,08355408 ! arginine metabolic process GO:0006525 21 14 0,000 0,05338842 0,08350058 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05338842 0,08344716 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05338842 0,08339381 ! regulation of heart rate GO:0002027 25 14 0,000 0,05338842 0,08334052 ! fear response GO:0042596 34 14 0,000 0,05338842 0,0832873 ! organic alcohol transport GO:0015850 29 14 0,000 0,05338842 0,08323415 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05338842 0,08318107 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,05338842 0,08312805 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05338842 0,0830751 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05338842 0,08302222 ! bone mineralization GO:0030282 18 14 0,000 0,05338842 0,08296941 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05338842 0,08291666 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05338842 0,08286399 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05338842 0,08281137 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,05338842 0,08275883 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05338842 0,08270635 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05338842 0,08265394 ! ribosome assembly GO:0042255 18 14 0,000 0,05338842 0,08260159 ! cerebellum development GO:0021549 23 14 0,000 0,05338842 0,08254931 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05338842 0,0824971 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05338842 0,08244495 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05338842 0,08239287 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05338842 0,08234085 ! NADP metabolic process GO:0006739 24 14 0,000 0,05338842 0,0822889 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,05338842 0,08223702 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05338842 0,0821852 ! regulation of RNA stability GO:0043487 33 14 0,000 0,05338842 0,08213345 ! regulation of axon extension GO:0030516 43 14 0,000 0,05338842 0,08208176 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05338842 0,08203013 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,05555993 0,08531296 ! transcription initiation GO:0006352 171 97 1,000 0,05555993 0,08525937 ! leukocyte differentiation GO:0002521 232 98 1,000 0,05657598 0,08676404 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05709174 0,08750008 ! lactation GO:0007595 30 15 0,000 0,05709174 0,08744522 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,05709174 0,08739043 ! reproductive cellular process GO:0048610 22 15 0,000 0,05709174 0,08733571 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05709174 0,08728106 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05709174 0,08722647 ! superoxide anion generation GO:0042554 22 15 0,000 0,05709174 0,08717195 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05709174 0,08711751 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,05709174 0,08706313 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05709174 0,08700881 ! copper ion transport GO:0006825 22 15 0,000 0,05709174 0,08695457 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05709174 0,08690039 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,05709174 0,08684628 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05709174 0,08679224 ! sulfate transport GO:0008272 27 15 0,000 0,05709174 0,08673826 ! response to cAMP GO:0051591 25 15 0,000 0,05709174 0,08668435 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05709174 0,08663051 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,05709174 0,08657674 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05709174 0,08652303 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,05709174 0,08646939 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,05709174 0,08641582 ! vesicle coating GO:0006901 38 15 0,000 0,05709174 0,08636231 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,05709174 0,08630887 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,05709174 0,08625549 ! regulation of exocytosis GO:0017157 26 15 0,000 0,05709174 0,08620218 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05709174 0,08614894 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05709174 0,08609576 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05709174 0,08604264 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,05709174 0,0859896 ! regulation of vasodilation GO:0042312 27 15 0,000 0,05709174 0,08593662 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05709174 0,0858837 ! histone deacetylation GO:0016575 24 15 0,000 0,05709174 0,08583085 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05709174 0,08577806 ! water homeostasis GO:0030104 28 15 0,000 0,05709174 0,08572534 ! cofactor transport GO:0051181 30 15 0,000 0,05709174 0,08567268 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05709174 0,08562009 ! muscle maintenance GO:0046716 26 15 0,000 0,05709174 0,08556756 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05709174 0,0855151 ! intestinal absorption GO:0050892 31 15 0,000 0,05709174 0,0854627 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05709174 0,08541037 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05709174 0,08535809 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05709174 0,08530589 ! cell killing GO:0001906 32 15 0,000 0,05709174 0,08525374 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,05709174 0,08520167 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05709174 0,08514965 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05709174 0,0850977 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05709174 0,08504581 ! actin filament polymerization GO:0030041 27 15 0,000 0,05709174 0,08499398 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05709174 0,08494222 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,05862752 0,08717409 GO:0060538|skeletal muscle organ development, ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06078068 0,09032068 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06078068 0,09026578 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06078068 0,09021094 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06078068 0,09015616 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06078068 0,09010146 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06078068 0,09004682 ! bone remodeling GO:0046849 28 16 0,000 0,06078068 0,08999224 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06078068 0,08993773 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06078068 0,08988329 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06078068 0,08982892 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06078068 0,08977461 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06078068 0,08972036 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06078068 0,08966618 ! startle response GO:0001964 28 16 0,000 0,06078068 0,08961207 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06078068 0,08955802 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06078068 0,08950404 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06078068 0,08945012 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06078068 0,08939627 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06078068 0,08934248 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06078068 0,08928876 ! pituitary gland development GO:0021983 30 16 0,000 0,06078068 0,0892351 ! response to osmotic stress GO:0006970 27 16 0,000 0,06078068 0,0891815 ! lysosomal transport GO:0007041 31 16 0,000 0,06078068 0,08912797 ! fructose metabolic process GO:0006000 25 16 0,000 0,06078068 0,08907451 ! L-amino acid transport GO:0015807 33 16 0,000 0,06078068 0,0890211 ! stem cell development GO:0048864 46 16 0,000 0,06078068 0,08896777 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06078068 0,08891449 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06078068 0,08886128 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06078068 0,08880813 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06078068 0,08875505 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06078068 0,08870203 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06078068 0,08864907 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,06078068 0,08859618 ! DNA replication initiation GO:0006270 28 16 0,000 0,06078068 0,08854335 ! neuron recognition GO:0008038 40 16 0,000 0,06078068 0,08849058 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06078068 0,08843788 ! tissue regeneration GO:0042246 27 16 0,000 0,06078068 0,08838524 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06078068 0,08833266 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06078068 0,08828014 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,06078068 0,08822769 ! biomineral formation GO:0031214 22 16 0,000 0,06078068 0,0881753 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06078068 0,08812297 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06078068 0,0880707 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06078068 0,08801849 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06078068 0,08796635 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06078068 0,08791427 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06078068 0,08786225 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06078068 0,08781029 ! peptide hormone processing GO:0016486 27 16 0,000 0,06078068 0,08775839 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06445529 0,09300902 ! metencephalon development GO:0022037 32 17 0,000 0,06445529 0,09295411 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,06445529 0,09289927 ! signal complex assembly GO:0007172 47 17 0,000 0,06445529 0,0928445 ! filopodium assembly GO:0046847 42 17 0,000 0,06445529 0,09278979 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06445529 0,09273514 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06445529 0,09268056 ! glial cell development GO:0021782 28 17 0,000 0,06445529 0,09262604 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,06445529 0,09257159 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06445529 0,0925172 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,06445529 0,09246287 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06445529 0,09240861 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,06445529 0,09235441 ! myoblast differentiation GO:0045445 50 17 0,000 0,06445529 0,09230027 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06445529 0,0922462 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06445529 0,09219219 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,06445529 0,09213825 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,06445529 0,09208437 ! membrane budding GO:0006900 42 17 0,000 0,06445529 0,09203055 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06445529 0,09197679 ! regulation of protein binding GO:0043393 33 17 0,000 0,06445529 0,0919231 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06445529 0,09186947 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06445529 0,0918159 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06445529 0,09176239 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06445529 0,09170895 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06445529 0,09165557 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,06445529 0,09160225 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,06445529 0,09154899 ! steroid catabolic process GO:0006706 34 17 0,000 0,06445529 0,0914958 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,06445529 0,09144266 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,06445529 0,09138959 ! organic cation transport GO:0015695 32 17 0,000 0,06445529 0,09133658 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,06445529 0,09128363 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06445529 0,09123075 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,06445529 0,09117792 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,06811562 0,09630004 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,06811562 0,09624434 ! limbic system development GO:0021761 40 18 0,000 0,06811562 0,09618871 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06811562 0,09613314 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,06811562 0,09607764 ! adult walking behavior GO:0007628 36 18 0,000 0,06811562 0,0960222 ! patterning of blood vessels GO:0001569 43 18 0,000 0,06811562 0,09596682 ! heart looping GO:0001947 34 18 0,000 0,06811562 0,09591151 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,06811562 0,09585626 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,06811562 0,09580107 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,06811562 0,09574595 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,06811562 0,09569089 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,06811562 0,0956359 ! glycine metabolic process GO:0006544 30 18 0,000 0,06811562 0,09558097 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06811562 0,0955261 ! response to retinoic acid GO:0032526 31 18 0,000 0,06811562 0,09547129 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,06811562 0,09541655 ! DNA integration GO:0015074 32 18 0,000 0,06811562 0,09536187 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,06811562 0,09530725 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,06811562 0,0952527 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,06811562 0,09519821 ! neural crest cell migration GO:0001755 41 18 0,000 0,06811562 0,09514378 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,06811562 0,09508941 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,06811562 0,0950351 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,06811562 0,09498086 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,06811562 0,09492668 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,06811562 0,09487256 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,06811562 0,0948185 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,06811562 0,0947645 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,06811562 0,09471057 ! detection of bacterium GO:0016045 22 18 0,000 0,06811562 0,09465669 ! nerve development GO:0021675 34 18 0,000 0,06811562 0,09460288 ! defense response to virus GO:0051607 43 18 0,000 0,06811562 0,09454913 ! microspike assembly GO:0030035 46 18 0,000 0,06811562 0,09449544 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,06811562 0,09444181 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,06811562 0,09438824 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,07176174 0,09938431 ! positive regulation of translation GO:0045727 31 19 0,000 0,07176174 0,099328 ! negative regulation of defense response GO:0031348 27 19 0,000 0,07176174 0,09927176 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,07176174 0,09921558 ! neuron maturation GO:0042551 46 19 0,000 0,07176174 0,09915946 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,07176174 0,09910341 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,07176174 0,09904742 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,07176174 0,09899149 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,07176174 0,09893563 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07176174 0,09887982 ! memory GO:0007613 34 19 0,000 0,07176174 0,09882409 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,07176174 0,09876841 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,07176174 0,0987128 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,07176174 0,09865725 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,07176174 0,09860176 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,07176174 0,09854633 ! cerebral cortex development GO:0021987 40 19 0,000 0,07176174 0,09849097 ! response to vitamin A GO:0033189 32 19 0,000 0,07176174 0,09843567 ! heme metabolic process GO:0042168 40 19 0,000 0,07176174 0,09838043 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,07176174 0,09832525 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,07176174 0,09827014 ! response to fungus GO:0009620 26 19 0,000 0,07176174 0,09821509 ! peptide cross-linking GO:0018149 39 19 0,000 0,07176174 0,09816009 ! protein export from nucleus GO:0006611 40 19 0,000 0,07176174 0,09810516 ! heart process GO:0003015 32 19 0,000 0,07176174 0,0980503 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,07176174 0,09799549 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,07176174 0,09794074 ! visual learning GO:0008542 38 19 0,000 0,07176174 0,09788606 ! cellular pigmentation GO:0033059 37 19 0,000 0,07176174 0,09783143 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,07176174 0,09777687 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,07176174 0,09772237 ! vitamin transport GO:0051180 31 19 0,000 0,07176174 0,09766793 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,07176174 0,09761355 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,07176174 0,09755923 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,07176174 0,09750497 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,07176174 0,09745077 ! cilium assembly GO:0042384 38 19 0,000 0,07176174 0,09739663 ! peptide hormone secretion GO:0030072 32 19 0,000 0,07176174 0,09734255 ! protein secretion GO:0009306 45 20 0,000 0,07539369 0,10221242 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,07539369 0,10215573 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,07539369 0,10209911 ! positive regulation of ossification GO:0045778 50 20 0,000 0,07539369 0,10204254 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,07539369 0,10198604 ! skin development GO:0043588 42 20 0,000 0,07539369 0,1019296 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,07539369 0,10187322 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,07539369 0,10181691 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,07539369 0,10176066 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,07539369 0,10170447 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,07539369 0,10164834 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,07539369 0,10159227 ! response to vitamin GO:0033273 36 20 0,000 0,07539369 0,10153627 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,07539369 0,10148032 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,07539369 0,10142444 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,07539369 0,10136862 ! bile acid metabolic process GO:0008206 34 20 0,000 0,07539369 0,10131287 ! retinoid metabolic process GO:0001523 34 20 0,000 0,07539369 0,10125717 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,07539369 0,10120153 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,07539369 0,10114596 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,07539369 0,10109044 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,07539369 0,10103499 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,07539369 0,1009796 ! body fluid secretion GO:0007589 33 20 0,000 0,07539369 0,10092427 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,07539369 0,100869 ! peptide secretion GO:0002790 38 20 0,000 0,07539369 0,10081379 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,07539369 0,10075864 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,07539369 0,10070355 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,07539369 0,10064852 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,07539369 0,10059355 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,07539369 0,10053864 ! cell-cell junction organization GO:0045216 43 20 0,000 0,07539369 0,10048379 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,07539369 0,100429 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,07539369 0,10037427 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,07539369 0,1003196 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,07539369 0,10026499 ! regulation of glucose import GO:0046324 30 20 0,000 0,07539369 0,10021044 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,07539369 0,10015595 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,07539369 0,10010152 ! negative regulation of translation GO:0017148 32 20 0,000 0,07539369 0,10004714 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,07539369 0,09999283 ! regulation of cell killing GO:0031341 46 21 0,000 0,07901154 0,10473423 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,07901154 0,10467743 ! hormone secretion GO:0046879 39 21 0,000 0,07901154 0,10462069 ! lipid phosphorylation GO:0046834 43 21 0,000 0,07901154 0,10456402 ! cAMP metabolic process GO:0046058 41 21 0,000 0,07901154 0,10450741 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,07901154 0,10445086 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,07901154 0,10439436 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,07901154 0,10433794 ! ovarian follicle development GO:0001541 39 21 0,000 0,07901154 0,10428157 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,07901154 0,10422526 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,07901154 0,10416901 ! plasma membrane fusion GO:0045026 33 21 0,000 0,07901154 0,10411283 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,07901154 0,1040567 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,07901154 0,10400064 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,07901154 0,10394463 ! sensory perception of pain GO:0019233 33 21 0,000 0,07901154 0,10388869 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,07901154 0,1038328 ! diencephalon development GO:0021536 36 21 0,000 0,07901154 0,10377698 ! collagen fibril organization GO:0030199 62 21 0,000 0,07901154 0,10372121 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,07901154 0,10366551 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,07901154 0,10360987 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,07901154 0,10355428 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,07901154 0,10349876 ! collagen catabolic process GO:0030574 29 21 0,000 0,07901154 0,10344329 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,07901154 0,10338788 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,07901154 0,10333254 ! sperm-egg recognition GO:0035036 23 21 0,000 0,07901154 0,10327725 ! actin filament-based movement GO:0030048 47 21 0,000 0,07901154 0,10322202 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,08261532 0,10787239 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,08261532 0,10781476 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,08261532 0,1077572 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,08261532 0,1076997 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,08261532 0,10764226 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,08261532 0,10758488 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,08261532 0,10752756 ! vacuolar transport GO:0007034 41 22 0,000 0,08261532 0,10747031 ! fucose metabolic process GO:0006004 44 22 0,000 0,08261532 0,10741311 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,08261532 0,10735598 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,08261532 0,1072989 ! ureteric bud development GO:0001657 50 22 0,000 0,08261532 0,10724189 ! stem cell differentiation GO:0048863 57 22 0,000 0,08261532 0,10718494 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,08261532 0,10712805 ! cytolysis GO:0019835 27 22 0,000 0,08261532 0,10707121 ! renal system process GO:0003014 42 22 0,000 0,08261532 0,10701444 ! vasodilation GO:0042311 40 22 0,000 0,08261532 0,10695773 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,08261532 0,10690108 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,08261532 0,10684449 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,08261532 0,10678796 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,08261532 0,10673148 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,08261532 0,10667507 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,08261532 0,10661872 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,08261532 0,10656243 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,08261532 0,10650619 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,08261532 0,10645002 ! sarcomere organization GO:0045214 32 22 0,000 0,08261532 0,1063939 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,08261532 0,10633785 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,08261532 0,10628185 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,08261532 0,10622591 ! gut development GO:0048565 44 22 0,000 0,08261532 0,10617004 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,08261532 0,10611422 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,08261532 0,10605845 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,08620511 0,11060877 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,08620511 0,1105507 ! gluconeogenesis GO:0006094 38 23 0,000 0,08620511 0,1104927 ! glycerol metabolic process GO:0006071 40 23 0,000 0,08620511 0,11043476 ! viral genome replication GO:0019079 44 23 0,000 0,08620511 0,11037688 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,08620511 0,11031906 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,08620511 0,1102613 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,08620511 0,11020361 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,08620511 0,11014597 ! regeneration GO:0031099 42 23 0,000 0,08620511 0,11008839 ! axis specification GO:0009798 43 23 0,000 0,08620511 0,11003087 ! visual behavior GO:0007632 46 23 0,000 0,08620511 0,10997342 ! response to ethanol GO:0045471 47 23 0,000 0,08620511 0,10991602 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,08620511 0,10985868 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,08620511 0,1098014 ! peroxisome organization GO:0007031 43 23 0,000 0,08620511 0,10974418 ! lysosome organization GO:0007040 47 23 0,000 0,08620511 0,10968703 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,08620511 0,10962993 ! vesicle targeting GO:0006903 49 23 0,000 0,08620511 0,10957289 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,08620511 0,10951591 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,08620511 0,10945899 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,08620511 0,10940213 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,08620511 0,10934532 ! DNA modification GO:0006304 36 23 0,000 0,08620511 0,10928858 ! fatty acid transport GO:0015908 47 23 0,000 0,08620511 0,10923189 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,08620511 0,10917527 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,08620511 0,1091187 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,08620511 0,10906219 ! hormone transport GO:0009914 41 23 0,000 0,08620511 0,10900574 ! cell-cell recognition GO:0009988 28 23 0,000 0,08620511 0,10894935 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,08620511 0,10889301 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,08620511 0,10883674 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,08620511 0,10878052 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,08978096 0,11323432 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,08978096 0,11317589 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,08978096 0,11311752 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,08978096 0,11305921 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,08978096 0,11300097 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,08978096 0,11294278 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,08978096 0,11288465 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,08978096 0,11282658 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,08978096 0,11276857 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,08978096 0,11271062 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,08978096 0,11265273 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,08978096 0,1125949 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,08978096 0,11253713 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,08978096 0,11247942 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,08978096 0,11242177 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,08978096 0,11236418 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,08978096 0,11230664 ! membrane depolarization GO:0051899 45 24 0,000 0,08978096 0,11224917 ! pallium development GO:0021543 56 24 0,000 0,08978096 0,11219175 ! oogenesis GO:0048477 44 24 0,000 0,08978096 0,11213439 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,08978096 0,11207709 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,08978096 0,11201985 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,08978096 0,11196267 ! platelet activation GO:0030168 41 24 0,000 0,08978096 0,11190555 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,08978096 0,11184848 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,08978096 0,11179147 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,08978096 0,11173453 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,08978096 0,11167763 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,08978096 0,1116208 ! regulation of amine transport GO:0051952 41 24 0,000 0,08978096 0,11156402 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,08978096 0,11150731 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0933429 0,11587231 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0933429 0,11581347 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0933429 0,11575468 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0933429 0,11569595 ! phototransduction GO:0007602 37 25 0,000 0,0933429 0,11563728 ! keratinization GO:0031424 37 25 0,000 0,0933429 0,11557867 ! vacuole organization GO:0007033 49 25 0,000 0,0933429 0,11552012 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0933429 0,11546163 ! receptor metabolic process GO:0043112 53 25 0,000 0,0933429 0,1154032 ! chromosome condensation GO:0030261 48 25 0,000 0,0933429 0,11534482 ! regulation of behavior GO:0050795 48 25 0,000 0,0933429 0,11528651 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0933429 0,11522825 ! interaction with host GO:0051701 66 25 0,000 0,0933429 0,11517006 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0933429 0,11511192 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0933429 0,11505384 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0933429 0,11499582 ! liver development GO:0001889 55 25 0,000 0,0933429 0,11493786 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,09689102 0,11924673 ! initiation of viral infection GO:0019059 60 26 0,000 0,09689102 0,11918668 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,09689102 0,1191267 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,09689102 0,11906678 ! molting cycle process GO:0022404 52 26 0,000 0,09689102 0,11900691 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,09689102 0,11894711 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,09689102 0,11888737 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,09689102 0,11882769 ! spinal cord development GO:0021510 54 26 0,000 0,09689102 0,11876806 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,09689102 0,1187085 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,09689102 0,118649 ! digestive system process GO:0022600 49 26 0,000 0,09689102 0,11858955 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,09689102 0,11853017 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,09689102 0,11847085 ! osteoblast differentiation GO:0001649 63 26 0,000 0,09689102 0,11841158 ! neural crest cell development GO:0014032 59 26 0,000 0,09689102 0,11835237 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,09689102 0,11829323 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,09689102 0,11823414 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,09689102 0,11817511 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,09689102 0,11811614 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,09689102 0,11805723 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,09689102 0,11799838 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,09689102 0,11793959 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,09689102 0,11788085 ! blastocyst development GO:0001824 50 26 0,000 0,09689102 0,11782218 ! telomere organization GO:0032200 46 26 0,000 0,09689102 0,11776356 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,09689102 0,117705 ! neural tube closure GO:0001843 58 26 0,000 0,09689102 0,1176465 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,09689102 0,11758805 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,09689102 0,11752967 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,10042534 0,12175638 ! embryonic pattern specification GO:0009880 49 27 0,000 0,10042534 0,12169598 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,10042534 0,12163565 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,10042534 0,12157537 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,10042534 0,12151516 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,10042534 0,121455 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,10042534 0,12139491 ! iron ion transport GO:0006826 65 27 0,000 0,10042534 0,12133487 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,10042534 0,12127489 ! superoxide metabolic process GO:0006801 41 27 0,000 0,10042534 0,12121497 ! tube lumen formation GO:0035148 59 27 0,000 0,10042534 0,12115511 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,10042534 0,12109531 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,10042534 0,12103557 ! response to toxin GO:0009636 49 27 0,000 0,10042534 0,12097589 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,10042534 0,12091627 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,10042534 0,1208567 ! neuron fate commitment GO:0048663 52 28 0,000 0,10394593 0,12503196 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,10394593 0,12497043 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,10394593 0,12490896 ! protein amino acid acylation GO:0043543 59 28 0,000 0,10394593 0,12484755 ! vesicle docking GO:0048278 55 28 0,000 0,10394593 0,1247862 ! circadian rhythm GO:0007623 56 28 0,000 0,10394593 0,12472491 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,10394593 0,12466368 ! fat cell differentiation GO:0045444 57 28 0,000 0,10394593 0,12460251 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,10394593 0,1245414 ! sperm motility GO:0030317 37 28 0,000 0,10394593 0,12448035 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,10394593 0,12441936 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,10394593 0,12435843 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,10394593 0,12429756 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,10394593 0,12423675 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,10394593 0,124176 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,10394593 0,1241153 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,10394593 0,12405467 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,10394593 0,1239941 ! lipid oxidation GO:0034440 48 28 0,000 0,10394593 0,12393358 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,10394593 0,12387313 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,10745284 0,12798991 ! translational initiation GO:0006413 66 29 0,000 0,10745284 0,12792753 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,10745284 0,12786522 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,10745284 0,12780297 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,10745284 0,12774078 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,10745284 0,12767865 ! primary neural tube formation GO:0014020 61 29 0,000 0,10745284 0,12761658 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,10745284 0,12755457 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,10745284 0,12749262 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,10745284 0,12743073 ! somitogenesis GO:0001756 52 29 0,000 0,10745284 0,1273689 ! synaptogenesis GO:0007416 46 29 0,000 0,10745284 0,12730713 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,10745284 0,12724542 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,10745284 0,12718377 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,10745284 0,12712218 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,10745284 0,12706065 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,11094613 0,13112791 ! phenol metabolic process GO:0018958 56 30 0,000 0,11094613 0,13106451 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,11094613 0,13100116 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,11094613 0,13093787 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,11094613 0,13087465 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,11094613 0,13081149 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,11094613 0,13074838 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,11094613 0,13068534 ! acute-phase response GO:0006953 50 30 0,000 0,11094613 0,13062236 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,11094613 0,13055944 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,11094613 0,13049658 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,11094613 0,13043378 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,11094613 0,13037104 ! cell fate determination GO:0001709 64 30 0,000 0,11094613 0,13030836 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,11094613 0,13024575 ! phospholipid transport GO:0015914 65 30 0,000 0,11094613 0,13018319 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,11094613 0,13012069 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,11094613 0,13005825 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,11094613 0,12999587 ! regulation of coagulation GO:0050818 52 30 0,000 0,11094613 0,12993356 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,11442584 0,13394458 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,11442584 0,13388043 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,11442584 0,13381634 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,11442584 0,13375231 ! regulation of innate immune response GO:0045088 57 31 0,000 0,11442584 0,13368835 ! ovulation cycle process GO:0022602 55 31 0,000 0,11442584 0,13362444 ! peptide transport GO:0015833 60 31 0,000 0,11442584 0,1335606 ! detection of light stimulus GO:0009583 44 31 0,000 0,11442584 0,13349682 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,11442584 0,1334331 ! natural killer cell activation GO:0030101 50 31 0,000 0,11442584 0,13336943 ! cofactor catabolic process GO:0051187 54 31 0,000 0,11442584 0,13330583 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,11442584 0,13324229 ! eye morphogenesis GO:0048592 65 31 0,000 0,11442584 0,13317882 ! response to heat GO:0009408 54 31 0,000 0,11442584 0,1331154 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,11442584 0,13305204 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,11789203 0,13701724 ! collagen metabolic process GO:0032963 49 32 0,000 0,11789203 0,13695209 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,11789203 0,13688699 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,11789203 0,13682197 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,11789203 0,136757 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,11789203 0,13669209 ! mesoderm formation GO:0001707 73 32 0,000 0,11789203 0,13662725 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,11789203 0,13656246 ! ovulation cycle GO:0042698 57 32 0,000 0,11789203 0,13649774 ! BMP signaling pathway GO:0030509 71 32 0,000 0,11789203 0,13643308 ! hindbrain development GO:0030902 65 32 0,000 0,11789203 0,13636848 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,11789203 0,13630395 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,11789203 0,13623947 ! gene silencing GO:0016458 71 32 0,000 0,11789203 0,13617505 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,12134475 0,14009699 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,12134475 0,14003081 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,12134475 0,1399647 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,12134475 0,13989865 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,12134475 0,13983266 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,12134475 0,13976673 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,12134475 0,13970086 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,12134475 0,13963506 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,12134475 0,13956932 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,12134475 0,13950364 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,12478406 0,14339015 ! glial cell differentiation GO:0010001 67 34 0,000 0,12478406 0,14332273 ! post-embryonic development GO:0009791 76 34 0,000 0,12478406 0,14325538 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,12478406 0,14318809 ! cholesterol transport GO:0030301 62 34 0,000 0,12478406 0,14312087 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,12478406 0,14305371 ! spliceosome assembly GO:0000245 75 34 0,000 0,12478406 0,14298661 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,12478406 0,14291957 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,12478406 0,1428526 ! formation of primary germ layer GO:0001704 76 34 0,000 0,12478406 0,14278569 ! cell fate specification GO:0001708 56 34 0,000 0,12478406 0,14271884 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,12478406 0,14265206 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,12478406 0,14258534 ! adult locomotory behavior GO:0008344 62 34 0,000 0,12478406 0,14251868 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,12820999 0,14636309 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,12820999 0,14629473 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,12820999 0,14622643 ! membrane docking GO:0022406 69 35 0,000 0,12820999 0,1461582 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,12820999 0,14609002 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,12820999 0,14602192 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,12820999 0,14595387 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,12820999 0,14588589 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,12820999 0,14581798 ! ceramide metabolic process GO:0006672 72 35 0,000 0,12820999 0,14575012 ! telencephalon development GO:0021537 81 35 0,000 0,12820999 0,14568233 ! sterol transport GO:0015918 63 35 0,000 0,12820999 0,1456146 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,12820999 0,14554694 ! placenta development GO:0001890 53 35 0,000 0,12820999 0,14547934 ! vesicle localization GO:0051648 70 35 0,000 0,12820999 0,1454118 ! regulation of muscle development GO:0048634 82 36 0,000 0,13162262 0,14921302 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,13162262 0,14914381 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,13162262 0,14907466 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,13162262 0,14900558 ! positive regulation of cell development GO:0010720 85 36 0,000 0,13162262 0,14893657 ! protein targeting to membrane GO:0006612 75 36 0,000 0,13162262 0,14886762 ! regulation of proteolysis GO:0030162 77 36 0,000 0,13162262 0,14879873 ! aerobic respiration GO:0009060 56 36 0,000 0,13162262 0,1487299 ! cytokine production GO:0001816 68 36 0,000 0,13162262 0,14866114 ! embryonic organ development GO:0048568 67 36 0,000 0,13162262 0,14859244 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,13162262 0,14852381 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,13162262 0,14845524 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,13502197 0,15221905 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,13502197 0,15214884 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,13502197 0,15207869 ! tissue remodeling GO:0048771 78 37 0,000 0,13502197 0,15200861 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,13502197 0,15193859 ! female gonad development GO:0008585 71 37 0,000 0,13502197 0,15186864 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,13502197 0,15179875 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,13502197 0,15172893 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,13840812 0,15546255 ! organic anion transport GO:0015711 82 38 0,000 0,13840812 0,1553911 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,13840812 0,15531973 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,13840812 0,15524841 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,13840812 0,15517717 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,13840812 0,15510598 ! spermatid development GO:0007286 69 38 0,000 0,13840812 0,15503487 ! glycogen metabolic process GO:0005977 63 38 0,000 0,13840812 0,15496381 ! pigment metabolic process GO:0042440 87 38 0,000 0,13840812 0,15489283 ! neural tube formation GO:0001841 79 38 0,000 0,13840812 0,15482191 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,14178111 0,15852231 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,14178111 0,15844979 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,14178111 0,15837734 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,14178111 0,15830496 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,14178111 0,15823264 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,14178111 0,15816039 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,14178111 0,1580882 ! glucan metabolic process GO:0044042 64 39 0,000 0,14178111 0,15801608 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,14514099 0,16168693 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,14514099 0,16161323 ! learning GO:0007612 82 40 0,000 0,14514099 0,1615396 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,14514099 0,16146604 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,14514099 0,16139255 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,14514099 0,16131912 ! RNA export from nucleus GO:0006405 61 41 0,000 0,1484878 0,16496394 ! mRNA catabolic process GO:0006402 79 41 0,000 0,1484878 0,16488896 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,1484878 0,16481404 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,1484878 0,16473919 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,1484878 0,16466441 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,1484878 0,1645897 ! gliogenesis GO:0042063 91 41 0,000 0,1484878 0,16451506 ! feeding behavior GO:0007631 69 41 0,000 0,1484878 0,16444048 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,1484878 0,16436597 ! mesenchymal cell development GO:0014031 94 41 0,000 0,1484878 0,16429153 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,1484878 0,16421716 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,1484878 0,16414285 ! spermatid differentiation GO:0048515 73 41 0,000 0,1484878 0,16406861 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,1484878 0,16399444 ! RNA modification GO:0009451 64 41 0,000 0,1484878 0,16392034 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,15182161 0,16752493 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,15182161 0,1674493 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,15182161 0,16737374 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,15182161 0,16729824 ! regulation of protein secretion GO:0050708 77 42 0,000 0,15182161 0,16722281 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,15182161 0,16714745 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,15182161 0,16707216 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,15514246 0,17064972 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,15514246 0,17057292 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,15514246 0,17049619 ! segmentation GO:0035282 78 43 0,000 0,15514246 0,17041953 ! ion transmembrane transport GO:0034220 79 43 0,000 0,15514246 0,17034294 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,1584504 0,17389682 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,1584504 0,17381874 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,1584504 0,17374072 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,1584504 0,17366278 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,1584504 0,1735849 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,1584504 0,1735071 ! phagocytosis GO:0006909 105 44 0,000 0,1584504 0,17342936 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,1584504 0,17335169 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,16174548 0,17687745 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,16174548 0,17679831 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,16174548 0,17671924 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,16174548 0,17664024 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,16174548 0,17656131 ! female gamete generation GO:0007292 71 45 0,000 0,16174548 0,17648245 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,16174548 0,17640367 ! developmental growth GO:0048589 88 45 0,000 0,16174548 0,17632495 ! maintenance of location in cell GO:0051651 101 45 0,000 0,16174548 0,17624631 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,16502776 0,17974267 ! leukocyte migration GO:0050900 75 46 0,000 0,16502776 0,17966257 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,16502776 0,17958254 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,16502776 0,17950259 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,16502776 0,1794227 ! neural tube development GO:0021915 91 47 0,000 0,16829727 0,18289601 ! positive regulation of defense response GO:0031349 88 48 0,000 0,17155407 0,18635242 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,17155407 0,1862696 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,17155407 0,18618685 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,17155407 0,18610417 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,17155407 0,18602157 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,17155407 0,18593904 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,17155407 0,18585658 ! methylation GO:0032259 97 48 0,000 0,17155407 0,1857742 ! response to calcium ion GO:0051592 94 49 0,000 0,17479821 0,18920338 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,17479821 0,18911959 ! protein homooligomerization GO:0051260 84 49 0,000 0,17479821 0,18903587 ! regulation of ion transport GO:0043269 86 50 0,000 0,17802974 0,19244542 ! endocrine system development GO:0035270 109 50 0,000 0,17802974 0,1923603 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,17802974 0,19227526 ! regulation of ossification GO:0030278 123 50 0,000 0,17802974 0,1921903 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,17802974 0,19210541 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,17802974 0,19202059 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,17802974 0,19193585 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,1812487 0,19532006 ! viral infectious cycle GO:0019058 104 51 0,000 0,1812487 0,19523394 ! response to temperature stimulus GO:0009266 84 51 0,000 0,1812487 0,19514789 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,18445515 0,19851274 ! Notch signaling pathway GO:0007219 111 52 0,000 0,18445515 0,19842533 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,18445515 0,19833799 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,18445515 0,19825074 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,18445515 0,19816355 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,18445515 0,19807645 ! excretion GO:0007588 87 52 0,000 0,18445515 0,19798942 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,18445515 0,19790247 ! histone modification GO:0016570 104 52 0,000 0,18445515 0,19781559 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,18445515 0,19772879 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,18445515 0,19764207 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,18445515 0,19755542 ! amino acid activation GO:0043038 98 52 0,000 0,18445515 0,19746885 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,18764913 0,20080018 ! positive regulation of growth GO:0045927 96 53 0,000 0,18764913 0,20071227 ! inner ear development GO:0048839 89 53 0,000 0,18764913 0,20062443 ! chromatin remodeling GO:0006338 122 53 0,000 0,18764913 0,20053666 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,18764913 0,20044898 ! vesicle organization GO:0016050 127 53 0,000 0,18764913 0,20036137 ! cartilage development GO:0051216 99 53 0,000 0,18764913 0,20027384 ! regulation of translational initiation GO:0006446 87 54 0,000 0,19083069 0,20358051 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,19083069 0,20349165 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,19083069 0,20340287 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,19083069 0,20331416 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,19083069 0,20322553 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,19083069 0,20313698 ! membrane fusion GO:0006944 122 54 0,000 0,19083069 0,2030485 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,19083069 0,20296011 ! covalent chromatin modification GO:0016569 115 54 0,000 0,19083069 0,20287179 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,19083069 0,20278354 ! regulation of cell shape GO:0008360 142 54 0,000 0,19083069 0,20269538 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,19083069 0,20260729 ! RNA catabolic process GO:0006401 103 55 0,000 0,19399988 0,20588258 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,19399988 0,20579318 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,19399988 0,20570386 ! cell recognition GO:0008037 98 55 0,000 0,19399988 0,20561462 ! cell maturation GO:0048469 107 55 0,000 0,19399988 0,20552545 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,19715674 0,20877933 ! RNA elongation GO:0006354 90 56 0,000 0,19715674 0,20868887 ! chloride transport GO:0006821 102 57 0,000 0,20030133 0,21192558 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,20030133 0,21183383 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,20030133 0,21174217 ! heart morphogenesis GO:0003007 105 57 0,000 0,20030133 0,21165059 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,20343369 0,21486749 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,20343369 0,21477464 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,20343369 0,21468186 ! gastrulation GO:0007369 122 58 0,000 0,20343369 0,21458917 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,20343369 0,21449655 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,20343369 0,21440402 ! maintenance of location GO:0051235 124 58 0,000 0,20343369 0,21431156 ! nuclear export GO:0051168 110 59 0,000 0,20655387 0,21750479 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,20966192 0,22068249 ! regulation of endocytosis GO:0030100 104 60 0,000 0,20966192 0,22058745 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,20966192 0,2204925 ! adult behavior GO:0030534 104 60 0,000 0,20966192 0,22039762 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,21275788 0,22355591 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,21275788 0,2234598 ! regulation of heart contraction GO:0008016 123 61 0,000 0,21275788 0,22336377 ! proton transport GO:0015992 117 61 0,000 0,21275788 0,22326783 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,21275788 0,22317196 ! viral reproductive process GO:0022415 132 62 0,000 0,2158418 0,22630966 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,2158418 0,22621257 ! tRNA processing GO:0008033 102 62 0,000 0,2158418 0,22611557 ! mesoderm development GO:0007498 128 63 0,000 0,21891372 0,22923541 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,21891372 0,2291372 ! hydrogen transport GO:0006818 121 64 0,000 0,2219737 0,23224057 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,2219737 0,23214115 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,2219737 0,23204182 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,22502177 0,23512754 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,22502177 0,23502701 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,22502177 0,23492657 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,22805799 0,23799473 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,23108239 0,24104795 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,23108239 0,24094507 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,23108239 0,24084227 ! secondary metabolic process GO:0019748 125 67 0,000 0,23108239 0,24073957 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,23409504 0,24377416 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,23409504 0,24367029 ! viral reproduction GO:0016032 142 68 0,000 0,23409504 0,24356652 ! regulation of lipase activity GO:0060191 137 68 0,000 0,23409504 0,24346283 ! cell projection assembly GO:0030031 138 68 0,000 0,23409504 0,24335922 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,23709596 0,24637407 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,23709596 0,24626932 ! developmental maturation GO:0021700 128 69 0,000 0,23709596 0,24616466 ! single fertilization GO:0007338 83 69 0,000 0,23709596 0,24606008 ! cell redox homeostasis GO:0045454 114 70 0,000 0,24008521 0,24905655 ! activation of immune response GO:0002253 120 70 0,000 0,24008521 0,24895084 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,24008521 0,24884522 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,24306283 0,25182464 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,24306283 0,25171789 ! appendage morphogenesis GO:0035107 150 72 0,000 0,24602887 0,25468158 GO:0035108|limb morphogenesis, ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,24602887 0,25457371 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,24602887 0,25446593 ! appendage development GO:0048736 151 73 0,000 0,24898337 0,25741277 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,24898337 0,25730388 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,24898337 0,25719509 ! regulation of immune effector process GO:0002697 156 73 0,000 0,24898337 0,25708638 ! acute inflammatory response GO:0002526 118 74 0,000 0,25192638 0,26001527 ! amino acid transport GO:0006865 148 74 0,000 0,25192638 0,25990546 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,25192638 0,25979575 ! transition metal ion transport GO:0000041 143 75 0,000 0,25485793 0,26270798 ! rhythmic process GO:0048511 142 75 0,000 0,25485793 0,26259718 ! learning or memory GO:0007611 161 76 0,000 0,25777808 0,26549403 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,25777808 0,26538215 ! amine catabolic process GO:0009310 136 77 0,000 0,26068687 0,2682637 ! neurotransmitter transport GO:0006836 142 77 0,000 0,26068687 0,26815074 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,26068687 0,26803788 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,26068687 0,26792512 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,26358433 0,27078912 ! antigen processing and presentation GO:0019882 117 78 0,000 0,26358433 0,2706753 ! fertilization GO:0009566 99 78 0,000 0,26358433 0,27056157 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,26358433 0,27044793 ! blood coagulation GO:0007596 151 79 0,000 0,26647053 0,2732945 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 0,000 0,26647053 0,27317982 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,26647053 0,27306523 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,26647053 0,27295073 ! response to hypoxia GO:0001666 178 81 0,000 0,27220927 0,27871217 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,27220927 0,27859541 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,27220927 0,27847875 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,27790343 0,28418505 ! exocytosis GO:0006887 153 83 0,000 0,27790343 0,28406615 ! response to oxygen levels GO:0070482 183 83 0,000 0,27790343 0,28394734 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,27790343 0,28382863 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,27790343 0,28371002 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,27790343 0,28359152 ! inorganic anion transport GO:0015698 156 83 0,000 0,27790343 0,28347311 ! response to metal ion GO:0010038 158 84 0,000 0,28073391 0,28624079 ! response to nutrient GO:0007584 135 84 0,000 0,28073391 0,28612137 ! digestion GO:0007586 130 84 0,000 0,28073391 0,28600206 ! hemostasis GO:0007599 165 85 0,000 0,28355337 0,28875401 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,28355337 0,2886337 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,28355337 0,28851348 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,28355337 0,28839337 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,28355337 0,28827335 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,28636185 0,29100749 ! regulation of lyase activity GO:0051339 169 86 0,000 0,28636185 0,29088649 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,28636185 0,29076559 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,28915941 0,29348418 ! nucleosome assembly GO:0006334 126 87 0,000 0,28915941 0,2933623 ! cellular respiration GO:0045333 143 88 0,000 0,29194607 0,29606652 ! sensory perception of smell GO:0007608 117 88 0,000 0,29194607 0,29594367 ! chromatin assembly GO:0031497 128 88 0,000 0,29194607 0,29582093 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,29194607 0,29569828 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,29472189 0,29838607 ! tube morphogenesis GO:0035239 194 89 0,000 0,29472189 0,29826246 ! cellular defense response GO:0006968 123 89 0,000 0,29472189 0,29813896 ! regulation of neurological system process GO:0031644 175 89 0,000 0,29472189 0,29801556 ! response to inorganic substance GO:0010035 173 90 0,000 0,29748691 0,30068702 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,29748691 0,30056266 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,29748691 0,30043841 ! response to unfolded protein GO:0006986 139 90 0,000 0,29748691 0,30031426 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,30024116 0,3029695 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,30024116 0,30284441 ! defense response to bacterium GO:0042742 112 91 0,000 0,30024116 0,30271942 ! bone development GO:0060348 206 92 0,000 0,3029847 0,30535958 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,3029847 0,30523366 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,30571755 0,30785984 ! amine transport GO:0015837 181 93 0,000 0,30571755 0,30773299 ! vitamin metabolic process GO:0006766 153 93 0,000 0,30571755 0,30760625 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,30843977 0,31021752 ! female pregnancy GO:0007565 166 94 0,000 0,30843977 0,31008986 ! sterol metabolic process GO:0016125 166 94 0,000 0,30843977 0,3099623 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,30843977 0,30983485 ! regulation of defense response GO:0031347 171 95 0,000 0,31115138 0,31243026 ! nucleosome organization GO:0034728 143 95 0,000 0,31115138 0,3123019 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,31115138 0,31217365 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,31115138 0,3120455 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,31115138 0,31191745 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,31115138 0,31178951 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,31115138 0,31166168 ! response to protein stimulus GO:0051789 158 96 0,000 0,31385245 0,31423833 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,31922307 0,31948462 ! mRNA transport GO:0051028 185 100 0,000 0,32455195 0,32468485 ! positive regulation of immune response GO:0050778 175 100 0,000 0,32455195 0,32455195