pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6610-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! peptidyl-amino acid modification GO:0018193 61 59 6,000 3,958E-07 7,295E-04 ! cell-substrate junction assembly GO:0007044 11 10 3,000 7,974E-07 7,348E-04 ! regulation of mitotic cell cycle GO:0007346 72 69 6,000 1,176E-06 7,223E-04 ! memory GO:0007613 5 5 2,000 5,05E-06 2,327E-03 ! cell junction assembly GO:0034329 18 17 3,000 8,661E-06 3,193E-03 ! pigmentation GO:0043473 17 17 3,000 8,661E-06 2,66E-03 ! regulation of lipid kinase activity GO:0043550 6 6 2,000 1,004E-05 2,644E-03 ! focal adhesion formation GO:0048041 7 6 2,000 1,004E-05 2,314E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 2,000 1,004E-05 2,057E-03 ! nitric oxide metabolic process GO:0046209 6 6 2,000 1,004E-05 1,851E-03 GO:0006809|nitric oxide biosynthetic process, ! lung development GO:0030324 38 37 4,000 1,065E-05 1,784E-03 ! respiratory tube development GO:0030323 40 39 4,000 1,389E-05 2,133E-03 ! respiratory system development GO:0060541 40 39 4,000 1,389E-05 1,969E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 3,000 1,394E-05 1,835E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 3,000 1,731E-05 2,127E-03 ! dopamine metabolic process GO:0042417 7 7 2,000 1,747E-05 2,013E-03 ! cell junction organization GO:0034330 23 22 3,000 2,583E-05 2,8E-03 ! negative regulation of blood coagulation GO:0030195 9 8 2,000 2,78E-05 2,846E-03 ! peptidyl-serine modification GO:0018209 8 8 2,000 2,78E-05 2,696E-03 ! response to ethanol GO:0045471 9 9 2,000 4,145E-05 3,82E-03 ! tube development GO:0035295 83 81 5,000 4,486E-05 3,937E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 4,000 5,261E-05 4,407E-03 GO:0051325|interphase, ! negative regulation of coagulation GO:0050819 11 10 2,000 5,888E-05 4,718E-03 ! positive regulation of cell differentiation GO:0045597 87 85 5,000 5,896E-05 4,527E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 6,971E-05 5,139E-03 ! myeloid leukocyte differentiation GO:0002573 12 11 2,000 8,049E-05 5,705E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 8,049E-05 5,494E-03 GO:0032388|positive regulation of intracellular transport, ! hindbrain development GO:0030902 11 11 2,000 8,049E-05 5,298E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 2,000 1,067E-04 6,781E-03 ! positive regulation of multicellular organism growth GO:0040018 12 12 2,000 1,067E-04 6,555E-03 ! G1 phase GO:0051318 13 12 2,000 1,067E-04 6,343E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 2,000 1,067E-04 6,145E-03 ! morphogenesis of an epithelium GO:0002009 63 62 4,000 1,354E-04 7,562E-03 GO:0060429|epithelium development, ! phenol metabolic process GO:0018958 13 13 2,000 1,379E-04 7,475E-03 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 2,000 1,379E-04 7,262E-03 ! receptor metabolic process GO:0043112 14 13 2,000 1,379E-04 7,06E-03 ! negative regulation of protein catabolic process GO:0042177 13 13 2,000 1,379E-04 6,869E-03 ! response to cytokine stimulus GO:0034097 13 13 2,000 1,379E-04 6,689E-03 ! hemopoiesis GO:0030097 104 100 5,000 1,463E-04 6,915E-03 ! response to peptide hormone stimulus GO:0043434 36 34 3,000 1,523E-04 7,016E-03 ! multicellular organismal response to stress GO:0033555 14 14 2,000 1,745E-04 7,844E-03 ! regulation of blood coagulation GO:0030193 15 14 2,000 1,745E-04 7,658E-03 ! regulation of mitosis GO:0007088 37 36 3,000 1,911E-04 8,19E-03 GO:0051783|regulation of nuclear division, ! response to drug GO:0042493 37 37 3,000 2,13E-04 8,92E-03 ! wound healing GO:0042060 74 70 4,000 2,41E-04 9,872E-03 ! regulation of coagulation GO:0050818 17 16 2,000 2,654E-04 0,01063285 ! myeloid cell differentiation GO:0030099 42 40 3,000 2,894E-04 0,01134812 ! development of primary male sexual characteristics GO:0046546 17 17 2,000 3,204E-04 0,01230208 ! negative regulation of catabolic process GO:0009895 18 18 2,000 3,823E-04 0,01437796 ! multicellular organismal metabolic process GO:0044236 19 19 2,000 4,513E-04 0,01663604 ! regulation of protein stability GO:0031647 19 19 2,000 4,513E-04 0,01630984 ! placenta development GO:0001890 19 19 2,000 4,513E-04 0,01599619 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 4,984E-04 0,0173301 ! regulation of membrane potential GO:0042391 46 46 3,000 4,984E-04 0,01700917 ! actin filament organization GO:0007015 50 48 3,000 5,871E-04 0,01967403 ! regulation of cell cycle process GO:0010564 50 48 3,000 5,871E-04 0,0193227 ! mitotic sister chromatid segregation GO:0000070 21 21 2,000 6,124E-04 0,0197998 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 6,124E-04 0,01945843 ! regulation of multicellular organism growth GO:0040014 21 21 2,000 6,124E-04 0,01912862 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 2,000 6,124E-04 0,01880981 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 6,124E-04 0,01850145 ! leukocyte differentiation GO:0002521 50 49 3,000 6,355E-04 0,01888987 ! gland development GO:0048732 51 49 3,000 6,355E-04 0,01859003 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 6,355E-04 0,01829956 ! positive regulation of protein ubiquitination GO:0031398 5 5 1,000 6,406E-04 0,01816416 ! prostate gland development GO:0030850 5 5 1,000 6,406E-04 0,01788895 ! metencephalon development GO:0022037 5 5 1,000 6,406E-04 0,01762195 ! filopodium assembly GO:0046847 7 5 1,000 6,406E-04 0,0173628 GO:0030035|microspike assembly, ! GTP metabolic process GO:0046039 5 5 1,000 6,406E-04 0,01711117 ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 6,406E-04 0,01686672 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 6,406E-04 0,01662916 ! response to lipid GO:0033993 5 5 1,000 6,406E-04 0,0163982 ! hippocampus development GO:0021766 6 5 1,000 6,406E-04 0,01617357 ! response to interferon-gamma GO:0034341 5 5 1,000 6,406E-04 0,01595501 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 6,406E-04 0,01574228 ! indolalkylamine metabolic process GO:0006586 5 5 1,000 6,406E-04 0,01553514 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 1,000 6,406E-04 0,01533338 ! receptor clustering GO:0043113 5 5 1,000 6,406E-04 0,0151368 ! fear response GO:0042596 5 5 1,000 6,406E-04 0,0149452 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 6,406E-04 0,01475838 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 6,406E-04 0,01457618 ! response to UV-B GO:0010224 5 5 1,000 6,406E-04 0,01439842 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 6,406E-04 0,01422495 ! response to amine stimulus GO:0014075 5 5 1,000 6,406E-04 0,0140556 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! decidualization GO:0046697 5 5 1,000 6,406E-04 0,01389024 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 6,406E-04 0,01372873 ! positive regulation of monooxygenase activity GO:0032770 5 5 1,000 6,406E-04 0,01357093 ! cellular pigmentation GO:0033059 5 5 1,000 6,406E-04 0,01341671 ! DNA methylation GO:0006306 5 5 1,000 6,406E-04 0,01326596 GO:0006305|DNA alkylation, ! T cell lineage commitment GO:0002360 5 5 1,000 6,406E-04 0,01311856 ! peptidyl-lysine modification GO:0018205 5 5 1,000 6,406E-04 0,0129744 ! neuromuscular process controlling posture GO:0050884 5 5 1,000 6,406E-04 0,01283338 ! oocyte differentiation GO:0009994 5 5 1,000 6,406E-04 0,01269538 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 1,000 6,406E-04 0,01256033 ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 6,406E-04 0,01242811 ! spleen development GO:0048536 5 5 1,000 6,406E-04 0,01229865 ! male genitalia development GO:0030539 5 5 1,000 6,406E-04 0,01217186 ! blastocyst formation GO:0001825 5 5 1,000 6,406E-04 0,01204766 ! response to nicotine GO:0035094 5 5 1,000 6,406E-04 0,01192597 ! nucleus localization GO:0051647 5 5 1,000 6,406E-04 0,01180671 ! positive regulation of transferase activity GO:0051347 91 88 4,000 6,982E-04 0,01274024 GO:0033674|positive regulation of kinase activity, ! sister chromatid segregation GO:0000819 22 22 2,000 7,05E-04 0,01273795 ! male sex differentiation GO:0046661 22 22 2,000 7,05E-04 0,01261428 ! cytokinesis GO:0000910 23 22 2,000 7,05E-04 0,01249299 ! brain development GO:0007420 91 90 4,000 7,737E-04 0,01357963 ! cell fate commitment GO:0045165 52 52 3,000 7,974E-04 0,01386459 ! epithelial cell differentiation GO:0030855 23 23 2,000 8,061E-04 0,01388384 ! positive regulation of growth GO:0045927 23 23 2,000 8,061E-04 0,01375529 ! response to hypoxia GO:0001666 53 53 3,000 8,573E-04 0,01449603 ! tissue morphogenesis GO:0048729 94 93 4,000 8,981E-04 0,01504747 ! glucose homeostasis GO:0042593 24 24 2,000 9,159E-04 0,01520754 GO:0033500|carbohydrate homeostasis, ! response to oxygen levels GO:0070482 55 54 3,000 9,204E-04 0,01514483 ! negative regulation of multicellular organismal process GO:0051241 55 54 3,000 9,204E-04 0,01501081 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 9,559E-04 0,01545396 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 9,559E-04 0,01531958 GO:0018409|peptide or protein amino-terminal blocking, ! succinate metabolic process GO:0006105 7 6 1,000 9,559E-04 0,01518751 ! limbic system development GO:0021761 7 6 1,000 9,559E-04 0,01505771 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 9,559E-04 0,0149301 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 1,000 9,559E-04 0,01480464 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! L-phenylalanine metabolic process GO:0006558 6 6 1,000 9,559E-04 0,01468126 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 6 6 1,000 9,559E-04 0,01455993 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 9,559E-04 0,01444059 GO:0070667|negative regulation of mast cell proliferation, ! negative regulation of ossification GO:0030279 6 6 1,000 9,559E-04 0,01432318 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 9,559E-04 0,01420767 ! genitalia development GO:0048806 6 6 1,000 9,559E-04 0,01409401 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 9,559E-04 0,01398216 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 9,559E-04 0,01387206 ! thymus development GO:0048538 6 6 1,000 9,559E-04 0,01376368 ! maternal placenta development GO:0001893 6 6 1,000 9,559E-04 0,01365699 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 1,035E-03 0,01467077 ! JAK-STAT cascade GO:0007259 26 25 2,000 1,035E-03 0,01455878 ! reproductive developmental process GO:0003006 56 56 3,000 1,056E-03 0,01474529 ! regulation of binding GO:0051098 60 57 3,000 1,129E-03 0,0156444 ! regulation of protein localization GO:0032880 58 57 3,000 1,129E-03 0,01552765 ! response to insulin stimulus GO:0032868 28 26 2,000 1,163E-03 0,01587837 ! response to hormone stimulus GO:0009725 102 100 4,000 1,246E-03 0,01688659 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 1,301E-03 0,0175013 ! learning or memory GO:0007611 28 27 2,000 1,301E-03 0,01737448 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,331E-03 0,01765159 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 1,331E-03 0,01752551 ! pteridine and derivative biosynthetic process GO:0042559 7 7 1,000 1,331E-03 0,01740121 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 1,331E-03 0,01727867 GO:0000725|recombinational repair, ! hair follicle morphogenesis GO:0031069 7 7 1,000 1,331E-03 0,01715784 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 1,331E-03 0,01703869 ! visual behavior GO:0007632 7 7 1,000 1,331E-03 0,01692118 GO:0008542|visual learning, ! startle response GO:0001964 7 7 1,000 1,331E-03 0,01680528 ! digestive system development GO:0055123 7 7 1,000 1,331E-03 0,01669096 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 1,331E-03 0,01657818 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,331E-03 0,01646692 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! regulation of exocytosis GO:0017157 8 7 1,000 1,331E-03 0,01635714 ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 1,331E-03 0,01624882 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 1,000 1,331E-03 0,01614192 ! purine ribonucleotide catabolic process GO:0009154 7 7 1,000 1,331E-03 0,01603641 ! induction of an organ GO:0001759 7 7 1,000 1,331E-03 0,01593228 ! response to gamma radiation GO:0010332 8 7 1,000 1,331E-03 0,01582949 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 1,331E-03 0,01572802 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,331E-03 0,01562784 ! neuromuscular process GO:0050905 28 28 2,000 1,449E-03 0,01689862 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 1,607E-03 0,01862241 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,607E-03 0,01850602 ! positive regulation of protein transport GO:0051222 29 29 2,000 1,607E-03 0,01839108 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 1,766E-03 0,0200886 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,766E-03 0,01996535 ! embryonic forelimb morphogenesis GO:0035115 8 8 1,000 1,766E-03 0,01984361 ! folic acid and derivative biosynthetic process GO:0009396 8 8 1,000 1,766E-03 0,01972335 ! response to pain GO:0048265 8 8 1,000 1,766E-03 0,01960453 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 1,000 1,766E-03 0,01948714 ! T cell selection GO:0045058 8 8 1,000 1,766E-03 0,01937115 ! glycine metabolic process GO:0006544 8 8 1,000 1,766E-03 0,01925652 ! ribonucleotide catabolic process GO:0009261 8 8 1,000 1,766E-03 0,01914325 ! phosphagen metabolic process GO:0006599 8 8 1,000 1,766E-03 0,0190313 GO:0006600|creatine metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 1,766E-03 0,01892065 ! alpha-beta T cell activation GO:0046631 8 8 1,000 1,766E-03 0,01881129 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 1,766E-03 0,01870318 ! nucleoside triphosphate catabolic process GO:0009143 8 8 1,000 1,766E-03 0,0185963 ! T cell homeostasis GO:0043029 8 8 1,000 1,766E-03 0,01849064 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 1,766E-03 0,01838617 ! catecholamine biosynthetic process GO:0042423 8 8 1,000 1,766E-03 0,01828288 ! aromatic compound biosynthetic process GO:0019438 8 8 1,000 1,766E-03 0,01818074 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,766E-03 0,01807974 ! developmental induction GO:0031128 8 8 1,000 1,766E-03 0,01797985 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,766E-03 0,01788106 ! response to reactive oxygen species GO:0000302 31 30 2,000 1,775E-03 0,01787477 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 2,000 1,775E-03 0,01777762 ! establishment of organelle localization GO:0051656 31 30 2,000 1,775E-03 0,01768152 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 1,951E-03 0,01933457 ! negative regulation of protein metabolic process GO:0051248 66 66 3,000 1,951E-03 0,01923118 ! regulation of DNA replication GO:0006275 32 31 2,000 1,954E-03 0,01915309 ! regulation of intracellular transport GO:0032386 31 31 2,000 1,954E-03 0,01905175 ! striated muscle tissue development GO:0014706 69 67 3,000 2,063E-03 0,02000861 ! negative regulation of cell growth GO:0030308 32 32 2,000 2,144E-03 0,02068319 ! cell maturation GO:0048469 32 32 2,000 2,144E-03 0,02057547 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 2,144E-03 0,02046886 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 2,144E-03 0,02036335 ! response to radiation GO:0009314 70 68 3,000 2,179E-03 0,02058988 ! regulation of cell size GO:0008361 68 68 3,000 2,179E-03 0,02048483 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 2,258E-03 0,02112863 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 2,258E-03 0,02102192 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 2,258E-03 0,02091628 ! regulation of postsynaptic membrane potential GO:0060078 9 9 1,000 2,258E-03 0,0208117 ! response to alkaloid GO:0043279 10 9 1,000 2,258E-03 0,02070816 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 2,258E-03 0,02060564 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 2,258E-03 0,02050414 ! cerebral cortex development GO:0021987 9 9 1,000 2,258E-03 0,02040363 ! pigmentation during development GO:0048066 9 9 1,000 2,258E-03 0,0203041 ! neurotransmitter metabolic process GO:0042133 11 9 1,000 2,258E-03 0,02020553 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 2,258E-03 0,02010792 GO:0060675|ureteric bud morphogenesis, ! regulation of dephosphorylation GO:0035303 9 9 1,000 2,258E-03 0,02001125 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 2,258E-03 0,0199155 ! prostaglandin metabolic process GO:0006693 9 9 1,000 2,258E-03 0,01982066 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 1,000 2,258E-03 0,01972673 ! histone acetylation GO:0016573 9 9 1,000 2,258E-03 0,01963368 ! positive regulation of oxidoreductase activity GO:0051353 9 9 1,000 2,258E-03 0,0195415 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,258E-03 0,01945019 ! collagen catabolic process GO:0030574 9 9 1,000 2,258E-03 0,01935972 ! aromatic amino acid family catabolic process GO:0009074 9 9 1,000 2,258E-03 0,01927009 ! estrogen receptor signaling pathway GO:0030520 9 9 1,000 2,258E-03 0,01918129 ! defense response to virus GO:0051607 9 9 1,000 2,258E-03 0,0190933 ! negative regulation of cell size GO:0045792 33 33 2,000 2,344E-03 0,01972889 ! muscle tissue development GO:0060537 72 70 3,000 2,423E-03 0,02030182 ! regulation of protein catabolic process GO:0042176 35 34 2,000 2,556E-03 0,02131942 ! regulation of angiogenesis GO:0045765 35 34 2,000 2,556E-03 0,02122339 ! ear development GO:0043583 34 34 2,000 2,556E-03 0,02112821 ! regulation of lipid metabolic process GO:0019216 34 34 2,000 2,556E-03 0,02103389 ! multicellular organism reproduction GO:0032504 36 35 2,000 2,78E-03 0,02277234 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of phosphorylation GO:0042327 35 35 2,000 2,78E-03 0,02267158 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 2,808E-03 0,02280087 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 2,808E-03 0,02270087 ! pteridine and derivative metabolic process GO:0042558 10 10 1,000 2,808E-03 0,02260173 ! forelimb morphogenesis GO:0035136 10 10 1,000 2,808E-03 0,02250347 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 2,808E-03 0,02240605 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 2,808E-03 0,02230947 ! fat cell differentiation GO:0045444 10 10 1,000 2,808E-03 0,02221372 ! epidermis morphogenesis GO:0048730 10 10 1,000 2,808E-03 0,02211879 ! exocrine system development GO:0035272 10 10 1,000 2,808E-03 0,02202467 ! neuromuscular junction development GO:0007528 10 10 1,000 2,808E-03 0,02193134 ! regulation of protein binding GO:0043393 11 10 1,000 2,808E-03 0,02183881 ! gland morphogenesis GO:0022612 10 10 1,000 2,808E-03 0,02174705 ! folic acid and derivative metabolic process GO:0006760 10 10 1,000 2,808E-03 0,02165606 ! lymphocyte homeostasis GO:0002260 10 10 1,000 2,808E-03 0,02156582 ! gut development GO:0048565 10 10 1,000 2,808E-03 0,02147634 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,808E-03 0,02138759 ! protein stabilization GO:0050821 10 10 1,000 2,808E-03 0,02129958 ! positive regulation of cell migration GO:0030335 36 36 2,000 3,015E-03 0,02277688 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 3,015E-03 0,02268391 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 2,000 3,015E-03 0,0225917 ! coagulation GO:0050817 39 36 2,000 3,015E-03 0,02250024 GO:0007596|blood coagulation, ! regulation of transcription factor activity GO:0051090 38 37 2,000 3,263E-03 0,02424718 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 2,000 3,263E-03 0,0241498 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 3,263E-03 0,0240532 ! negative regulation of growth GO:0045926 37 37 2,000 3,263E-03 0,02395737 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 3,415E-03 0,02497226 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 3,415E-03 0,02487356 ! signal complex assembly GO:0007172 11 11 1,000 3,415E-03 0,02477563 ! protein amino acid acetylation GO:0006473 11 11 1,000 3,415E-03 0,02467847 ! regulation of viral genome replication GO:0045069 11 11 1,000 3,415E-03 0,02458207 ! response to lipopolysaccharide GO:0032496 11 11 1,000 3,415E-03 0,02448642 ! membrane depolarization GO:0051899 11 11 1,000 3,415E-03 0,02439151 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 3,415E-03 0,02429734 ! oogenesis GO:0048477 11 11 1,000 3,415E-03 0,02420388 ! aromatic amino acid family metabolic process GO:0009072 11 11 1,000 3,415E-03 0,02411115 ! proximal/distal pattern formation GO:0009954 11 11 1,000 3,415E-03 0,02401912 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 3,415E-03 0,0239278 ! negative regulation of kinase activity GO:0033673 38 38 2,000 3,522E-03 0,02458845 ! cell-matrix adhesion GO:0007160 39 38 2,000 3,522E-03 0,02449567 ! chromosome segregation GO:0007059 38 38 2,000 3,522E-03 0,02440358 ! urogenital system development GO:0001655 38 38 2,000 3,522E-03 0,02431218 ! meiotic cell cycle GO:0051321 38 38 2,000 3,522E-03 0,02422146 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 3,522E-03 0,02413142 ! regulation of protein modification process GO:0031399 79 78 3,000 3,593E-03 0,02452778 ! positive regulation of protein kinase cascade GO:0010740 79 78 3,000 3,593E-03 0,02443727 ! hemostasis GO:0007599 42 39 2,000 3,794E-03 0,02570608 ! positive regulation of protein modification process GO:0031401 39 39 2,000 3,794E-03 0,02561192 ! developmental maturation GO:0021700 39 39 2,000 3,794E-03 0,02551844 ! positive regulation of cell motion GO:0051272 39 39 2,000 3,794E-03 0,02542565 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 4,076E-03 0,02721842 ! heterophilic cell adhesion GO:0007157 12 12 1,000 4,076E-03 0,02712016 ! collagen metabolic process GO:0032963 12 12 1,000 4,076E-03 0,0270226 ! glutamate signaling pathway GO:0007215 12 12 1,000 4,076E-03 0,02692575 ! male gonad development GO:0008584 12 12 1,000 4,076E-03 0,02682958 ! renal system process GO:0003014 12 12 1,000 4,076E-03 0,0267341 ! pallium development GO:0021543 13 12 1,000 4,076E-03 0,0266393 ! regulation of chromosome organization GO:0033044 12 12 1,000 4,076E-03 0,02654517 ! somitogenesis GO:0001756 13 12 1,000 4,076E-03 0,0264517 ! aromatic compound catabolic process GO:0019439 13 12 1,000 4,076E-03 0,02635889 ! negative regulation of transferase activity GO:0051348 40 40 2,000 4,078E-03 0,02627878 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 4,078E-03 0,02618721 ! organelle localization GO:0051640 41 40 2,000 4,078E-03 0,02609629 ! cell cycle checkpoint GO:0000075 42 41 2,000 4,375E-03 0,02789861 ! cell-substrate adhesion GO:0031589 43 42 2,000 4,684E-03 0,02976986 ! development of primary sexual characteristics GO:0045137 42 42 2,000 4,684E-03 0,02966756 ! forebrain development GO:0030900 43 42 2,000 4,684E-03 0,02956596 ! one-carbon metabolic process GO:0006730 42 42 2,000 4,684E-03 0,02946505 ! cellular amino acid derivative metabolic process GO:0006575 87 84 3,000 4,689E-03 0,02939277 ! positive regulation of DNA replication GO:0045740 14 13 1,000 4,792E-03 0,02993878 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 4,792E-03 0,02983764 ! regeneration GO:0031099 13 13 1,000 4,792E-03 0,02973717 ! post-embryonic development GO:0009791 14 13 1,000 4,792E-03 0,02963739 ! negative regulation of protein modification process GO:0031400 13 13 1,000 4,792E-03 0,02953826 ! vasculogenesis GO:0001570 13 13 1,000 4,792E-03 0,0294398 ! mitochondrial membrane organization GO:0007006 13 13 1,000 4,792E-03 0,029342 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 4,792E-03 0,02924484 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 4,792E-03 0,02914832 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 1,000 4,792E-03 0,02905244 ! actin filament bundle formation GO:0051017 13 13 1,000 4,792E-03 0,02895718 ! ureteric bud development GO:0001657 13 13 1,000 4,792E-03 0,02886255 ! cell aging GO:0007569 13 13 1,000 4,792E-03 0,02876854 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 4,792E-03 0,02867513 ! regulation of viral reproduction GO:0050792 13 13 1,000 4,792E-03 0,02858233 ! long-chain fatty acid transport GO:0015909 13 13 1,000 4,792E-03 0,02849013 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 4,792E-03 0,02839852 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 4,792E-03 0,0283075 GO:0001952|regulation of cell-matrix adhesion, ! purine nucleotide catabolic process GO:0006195 13 13 1,000 4,792E-03 0,02821706 ! blastocyst development GO:0001824 13 13 1,000 4,792E-03 0,0281272 ! tissue homeostasis GO:0001894 13 13 1,000 4,792E-03 0,02803791 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 1,000 4,792E-03 0,02794918 ! regulation of cellular localization GO:0060341 86 85 3,000 4,891E-03 0,02843538 ! nitrogen compound biosynthetic process GO:0044271 86 85 3,000 4,891E-03 0,02834596 ! reproductive structure development GO:0048608 43 43 2,000 5,007E-03 0,02892698 ! homeostasis of number of cells GO:0048872 44 43 2,000 5,007E-03 0,02883658 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 5,099E-03 0,02927486 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 5,099E-03 0,02918395 ! male gamete generation GO:0048232 90 88 3,000 5,532E-03 0,03156729 GO:0007283|spermatogenesis, ! protein amino acid acylation GO:0043543 14 14 1,000 5,562E-03 0,03163682 ! mechanoreceptor differentiation GO:0042490 14 14 1,000 5,562E-03 0,03153947 ! hair cycle GO:0042633 14 14 1,000 5,562E-03 0,03144272 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 5,562E-03 0,03134657 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 5,562E-03 0,031251 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 5,562E-03 0,03115601 GO:0045936|negative regulation of phosphate metabolic process, ! response to organic cyclic substance GO:0014070 15 14 1,000 5,562E-03 0,0310616 ! DNA modification GO:0006304 14 14 1,000 5,562E-03 0,03096776 ! group transfer coenzyme metabolic process GO:0006752 14 14 1,000 5,562E-03 0,03087448 ! response to molecule of bacterial origin GO:0002237 14 14 1,000 5,562E-03 0,03078177 ! amine biosynthetic process GO:0009309 46 45 2,000 5,691E-03 0,03140528 ! regulation of DNA binding GO:0051101 47 45 2,000 5,691E-03 0,03131153 ! tube morphogenesis GO:0035239 47 46 2,000 6,054E-03 0,03320565 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 6,384E-03 0,03491338 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 6,384E-03 0,03481008 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 6,384E-03 0,0347074 ! striated muscle cell differentiation GO:0051146 16 15 1,000 6,384E-03 0,03460532 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 6,384E-03 0,03450384 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 6,384E-03 0,03440295 ! ovarian follicle development GO:0001541 15 15 1,000 6,384E-03 0,03430265 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 6,384E-03 0,03420293 ! response to ionizing radiation GO:0010212 16 15 1,000 6,384E-03 0,03410379 ! leukocyte homeostasis GO:0001776 15 15 1,000 6,384E-03 0,03400523 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 6,384E-03 0,03390723 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 6,384E-03 0,03380979 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 6,384E-03 0,03371292 ! protein homooligomerization GO:0051260 15 15 1,000 6,384E-03 0,0336166 ! regulation of blood pressure GO:0008217 48 47 2,000 6,43E-03 0,03376003 ! sex differentiation GO:0007548 47 47 2,000 6,43E-03 0,03366412 ! regulation of catabolic process GO:0009894 48 47 2,000 6,43E-03 0,03356875 ! skeletal muscle tissue development GO:0007519 50 49 2,000 7,222E-03 0,03760131 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 2,000 7,222E-03 0,03749539 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 7,258E-03 0,03757518 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 7,258E-03 0,03746993 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of synaptic plasticity GO:0048167 16 16 1,000 7,258E-03 0,03736527 ! learning GO:0007612 16 16 1,000 7,258E-03 0,03726118 ! positive regulation of mitosis GO:0045840 16 16 1,000 7,258E-03 0,03715768 GO:0051785|positive regulation of nuclear division, ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 7,258E-03 0,03705475 ! segmentation GO:0035282 17 16 1,000 7,258E-03 0,03695239 ! fatty acid beta-oxidation GO:0006635 16 16 1,000 7,258E-03 0,03685059 ! positive regulation of cell development GO:0010720 16 16 1,000 7,258E-03 0,03674936 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 7,258E-03 0,03664867 ! lymphocyte proliferation GO:0046651 16 16 1,000 7,258E-03 0,03654854 ! cell fate specification GO:0001708 16 16 1,000 7,258E-03 0,03644895 ! fatty acid transport GO:0015908 16 16 1,000 7,258E-03 0,03634991 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 7,258E-03 0,0362514 ! regulation of cell growth GO:0001558 97 96 3,000 7,513E-03 0,03742176 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 7,64E-03 0,03795074 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 2,000 7,64E-03 0,03784872 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 7,64E-03 0,03774725 ! biogenic amine metabolic process GO:0006576 52 51 2,000 8,071E-03 0,03977114 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 8,183E-03 0,0402176 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 8,183E-03 0,04011064 ! myelination GO:0042552 17 17 1,000 8,183E-03 0,04000425 ! leukocyte adhesion GO:0007159 17 17 1,000 8,183E-03 0,03989841 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 8,183E-03 0,03979314 ! glucose transport GO:0015758 17 17 1,000 8,183E-03 0,03968842 ! response to toxin GO:0009636 18 17 1,000 8,183E-03 0,03958425 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 8,183E-03 0,03948063 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 2,000 8,516E-03 0,04097939 ! regulation of body fluid levels GO:0050878 55 52 2,000 8,516E-03 0,04087267 ! response to light stimulus GO:0009416 53 52 2,000 8,516E-03 0,04076651 ! muscle organ development GO:0007517 102 100 3,000 8,658E-03 0,04134064 ! regulation of protein transport GO:0051223 53 53 2,000 8,976E-03 0,04274421 GO:0070201|regulation of establishment of protein localization, ! regulation of cell projection organization GO:0031344 19 18 1,000 9,158E-03 0,0435019 ! meiosis I GO:0007127 18 18 1,000 9,158E-03 0,04339007 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 9,158E-03 0,04327881 ! mononuclear cell proliferation GO:0032943 18 18 1,000 9,158E-03 0,04316812 GO:0070661|leukocyte proliferation, ! hexose transport GO:0008645 18 18 1,000 9,158E-03 0,043058 GO:0015749|monosaccharide transport, ! negative regulation of DNA binding GO:0043392 19 18 1,000 9,158E-03 0,04294844 ! telencephalon development GO:0021537 19 18 1,000 9,158E-03 0,04283943 ! B cell differentiation GO:0030183 18 18 1,000 9,158E-03 0,04273098 ! ensheathment of neurons GO:0007272 18 18 1,000 9,158E-03 0,04262307 GO:0008366|axon ensheathment, ! regulation of cell adhesion GO:0030155 56 55 2,000 9,938E-03 0,0461338 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 9,938E-03 0,04601789 ! DNA damage checkpoint GO:0000077 19 19 1,000 0,01018264 0,04703411 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 0,01018264 0,04691653 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 0,01018264 0,04679953 ! metanephros development GO:0001656 19 19 1,000 0,01018264 0,04668311 ! cellular response to oxidative stress GO:0034599 19 19 1,000 0,01018264 0,04656727 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01018264 0,04645201 ! biogenic amine biosynthetic process GO:0042401 20 19 1,000 0,01018264 0,04633731 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 0,01018264 0,04622318 ! response to heat GO:0009408 19 19 1,000 0,01018264 0,04610961 ! extracellular structure organization GO:0043062 56 56 2,000 0,0104404 0,04716091 ! regulation of muscle development GO:0048634 21 20 1,000 0,01125539 0,05071805 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 0,01125539 0,05059435 ! negative regulation of binding GO:0051100 21 20 1,000 0,01125539 0,05047125 ! neural tube development GO:0021915 21 20 1,000 0,01125539 0,05034874 ! lipid oxidation GO:0034440 20 20 1,000 0,01125539 0,05022683 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 1,000 0,01125539 0,05010551 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 0,01125539 0,04998478 ! innate immune response GO:0045087 58 58 2,000 0,01148965 0,05090244 ! carboxylic acid transport GO:0046942 59 59 2,000 0,01203631 0,05319645 GO:0015849|organic acid transport, ! cellular aromatic compound metabolic process GO:0006725 60 59 2,000 0,01203631 0,05306919 ! mammary gland development GO:0030879 23 21 1,000 0,01237571 0,05443539 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01237571 0,05430578 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01237571 0,05417679 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01237571 0,05404841 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01237571 0,05392064 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 0,01317406 0,05726365 ! carboxylic acid catabolic process GO:0046395 63 61 2,000 0,01317406 0,05712891 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 2,000 0,01317406 0,05699481 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01354278 0,0584528 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01354278 0,05831623 ! cellular amide metabolic process GO:0043603 22 22 1,000 0,01354278 0,05818029 ! odontogenesis GO:0042476 22 22 1,000 0,01354278 0,05804499 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01354278 0,05791031 ! ovulation cycle process GO:0022602 22 22 1,000 0,01354278 0,05777626 ! spindle organization GO:0007051 22 22 1,000 0,01354278 0,05764283 ! erythrocyte differentiation GO:0030218 23 22 1,000 0,01354278 0,05751001 ! biopolymer methylation GO:0043414 22 22 1,000 0,01354278 0,05737781 GO:0032259|methylation, ! neuron migration GO:0001764 22 22 1,000 0,01354278 0,0572462 ! fatty acid catabolic process GO:0009062 23 22 1,000 0,01354278 0,05711521 ! axonogenesis GO:0007409 66 62 2,000 0,01376526 0,05792094 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 0,01437142 0,06033377 ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,0147558 0,06180669 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,0147558 0,06166654 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0147558 0,06152702 ! female gonad development GO:0008585 23 23 1,000 0,0147558 0,06138813 ! lipid homeostasis GO:0055088 23 23 1,000 0,0147558 0,06124987 ! Rho protein signal transduction GO:0007266 24 23 1,000 0,0147558 0,06111223 ! cell projection assembly GO:0030031 25 23 1,000 0,0147558 0,06097521 ! regulation of response to external stimulus GO:0032101 65 64 2,000 0,01499258 0,06181506 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 0,01499258 0,06167708 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 0,0156288 0,06415118 ! mitochondrial transport GO:0006839 24 24 1,000 0,01601397 0,06558612 ! regulation of action potential GO:0001508 24 24 1,000 0,01601397 0,06544069 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 0,01601397 0,06529591 ! heterocycle biosynthetic process GO:0018130 24 24 1,000 0,01601397 0,06515177 ! T cell differentiation GO:0030217 24 24 1,000 0,01601397 0,06500827 ! nucleotide catabolic process GO:0009166 24 24 1,000 0,01601397 0,06486539 ! erythrocyte homeostasis GO:0034101 25 24 1,000 0,01601397 0,06472314 ! ovulation cycle GO:0042698 24 24 1,000 0,01601397 0,06458152 ! maintenance of protein location GO:0045185 25 24 1,000 0,01601397 0,06444051 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01601397 0,06430011 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,01601397 0,06416033 ! glucan metabolic process GO:0044042 25 24 1,000 0,01601397 0,06402116 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 0,01694655 0,0676028 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Ras protein signal transduction GO:0007265 69 67 2,000 0,01694655 0,06745679 ! endosome transport GO:0016197 25 25 1,000 0,01731651 0,06878087 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,01731651 0,06863295 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01731651 0,06848567 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01731651 0,06833902 ! icosanoid metabolic process GO:0006690 25 25 1,000 0,01731651 0,068193 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01731651 0,0680476 ! regionalization GO:0003002 70 69 2,000 0,01832494 0,07185717 ! response to nutrient levels GO:0031667 69 69 2,000 0,01832494 0,07170461 ! positive regulation of binding GO:0051099 27 26 1,000 0,01866262 0,07287122 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01866262 0,07271716 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01866262 0,07256375 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01866262 0,07241098 ! double-strand break repair GO:0006302 27 26 1,000 0,01866262 0,07225886 ! germ cell development GO:0007281 27 26 1,000 0,01866262 0,07210737 ! pigment metabolic process GO:0042440 26 26 1,000 0,01866262 0,07195652 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01866262 0,0718063 ! synapse organization GO:0050808 26 26 1,000 0,01866262 0,0716567 ! positive regulation of transport GO:0051050 71 70 2,000 0,01903695 0,072942 ! cell part morphogenesis GO:0032990 75 70 2,000 0,01903695 0,07279066 ! growth GO:0040007 70 70 2,000 0,01903695 0,07263996 ! regulation of cell migration GO:0030334 71 71 2,000 0,0197642 0,07525912 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 0,02005156 0,07619592 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,02005156 0,07603914 ! monocarboxylic acid transport GO:0015718 27 27 1,000 0,02005156 0,075883 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,02005156 0,0757275 ! mesenchymal cell development GO:0014031 29 27 1,000 0,02005156 0,07557264 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 1,000 0,02005156 0,07541841 ! cell growth GO:0016049 27 27 1,000 0,02005156 0,07526481 ! sensory organ development GO:0007423 72 72 2,000 0,02050669 0,07681675 ! response to extracellular stimulus GO:0009991 72 72 2,000 0,02050669 0,07666093 ! carbohydrate transport GO:0008643 28 28 1,000 0,02148255 0,08014642 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 0,02148255 0,07998451 ! histone modification GO:0016570 28 28 1,000 0,02148255 0,07982325 ! developmental growth GO:0048589 28 28 1,000 0,02148255 0,07966264 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,02148255 0,07950267 ! response to oxidative stress GO:0006979 76 75 2,000 0,02282584 0,08430467 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,02295484 0,08461153 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,02295484 0,08444265 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,02295484 0,08427443 ! covalent chromatin modification GO:0016569 29 29 1,000 0,02295484 0,08410689 ! response to UV GO:0009411 29 29 1,000 0,02295484 0,08394001 ! positive regulation of multicellular organismal process GO:0051240 76 76 2,000 0,02362947 0,08623586 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,02444838 0,08904816 ! response to temperature stimulus GO:0009266 30 30 1,000 0,02446769 0,08894272 ! regulation of ossification GO:0030278 30 30 1,000 0,02446769 0,08876763 ! vesicle organization GO:0016050 30 30 1,000 0,02446769 0,08859324 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 1,000 0,02446769 0,08841952 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02602038 0,09384649 ! membrane fusion GO:0006944 31 31 1,000 0,02602038 0,0936632 ! B cell activation GO:0042113 31 31 1,000 0,02602038 0,09348062 ! aging GO:0007568 32 31 1,000 0,02602038 0,09329875 ! extracellular matrix organization GO:0030198 31 31 1,000 0,02602038 0,09311758 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,02602038 0,09293712 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,02602038 0,09275736 ! regulation of locomotion GO:0040012 79 79 2,000 0,02613207 0,09297568 ! regulation of cell motion GO:0051270 79 79 2,000 0,02613207 0,09279654 ! neuron projection development GO:0031175 85 80 2,000 0,02699683 0,09568298 ! muscle fiber development GO:0048747 32 32 1,000 0,02761217 0,09767606 ! lipid modification GO:0030258 32 32 1,000 0,02761217 0,09748894 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,02761217 0,09730254 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02761217 0,09711685 ! kidney development GO:0001822 32 32 1,000 0,02761217 0,09693186 ! maintenance of location GO:0051235 33 32 1,000 0,02761217 0,09674758 ! MAPKKK cascade GO:0000165 82 81 2,000 0,02787684 0,0974896 ! lipid catabolic process GO:0016042 82 81 2,000 0,02787684 0,09730497 ! amino acid transport GO:0006865 33 33 1,000 0,02924235 0,10187836 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,02924235 0,10168614 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,02924235 0,10149464 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,02924235 0,10130386 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02924235 0,1011138 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,02924235 0,10092444 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,03091022 0,10648137 ! response to metal ion GO:0010038 34 34 1,000 0,03091022 0,10628271 ! muscle cell differentiation GO:0042692 35 34 1,000 0,03091022 0,10608479 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,03091022 0,10588761 ! coenzyme biosynthetic process GO:0009108 34 34 1,000 0,03091022 0,10569115 ! secondary metabolic process GO:0019748 34 34 1,000 0,03091022 0,10549543 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,03261507 0,11110828 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,03261507 0,11090328 ! heart development GO:0007507 90 87 2,000 0,03347637 0,11362236 ! response to inorganic substance GO:0010035 36 36 1,000 0,03435622 0,11639434 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,03435622 0,11618077 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,03435622 0,11596798 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,03435622 0,11575598 ! heterocycle catabolic process GO:0046700 36 36 1,000 0,03435622 0,11554474 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,03435622 0,11533428 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,03435622 0,11512458 ! gonad development GO:0008406 36 36 1,000 0,03435622 0,11491564 ! chemotaxis GO:0006935 90 89 2,000 0,03546394 0,11840588 GO:0042330|taxis, ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,03613299 0,12042153 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,03613299 0,12020416 ! cellular amino acid catabolic process GO:0009063 38 37 1,000 0,03613299 0,11998757 ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,03751161 0,12434155 ! axon guidance GO:0007411 39 38 1,000 0,0379447 0,12555133 ! regulation of neurological system process GO:0031644 38 38 1,000 0,0379447 0,12532633 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,0379447 0,12510213 ! fatty acid metabolic process GO:0006631 93 92 2,000 0,03855788 0,12689675 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,0397907 0,1307206 ! activation of MAPK activity GO:0000187 39 39 1,000 0,0397907 0,130488 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,0397907 0,13025622 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,0397907 0,13002527 ! limb development GO:0060173 39 39 1,000 0,0397907 0,12979514 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 1,000 0,0397907 0,12956582 ! rRNA transcription GO:0009303 5 5 0,000 0,04005198 0,13018659 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04005198 0,12995739 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04005198 0,129729 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,04005198 0,1295014 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,04005198 0,1292746 ! reproductive cellular process GO:0048610 5 5 0,000 0,04005198 0,1290486 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,04005198 0,12882338 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04005198 0,12859895 ! water transport GO:0006833 5 5 0,000 0,04005198 0,1283753 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,04005198 0,12815243 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04005198 0,12793033 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04005198 0,127709 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04005198 0,12748843 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04005198 0,12726862 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04005198 0,12704957 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04005198 0,12683127 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04005198 0,12661372 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04005198 0,12639692 ! CTP metabolic process GO:0046036 5 5 0,000 0,04005198 0,12618085 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04005198 0,12596553 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04005198 0,12575094 ! mRNA stabilization GO:0048255 5 5 0,000 0,04005198 0,12553707 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04005198 0,12532394 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04005198 0,12511152 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04005198 0,12489983 ! social behavior GO:0035176 5 5 0,000 0,04005198 0,12468885 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04005198 0,12447858 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04005198 0,12426902 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04005198 0,12406017 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04005198 0,12385201 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04005198 0,12364455 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04005198 0,12343779 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04005198 0,12323172 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04005198 0,12302633 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04005198 0,12282163 ! heart looping GO:0001947 5 5 0,000 0,04005198 0,12261761 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04005198 0,12241426 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04005198 0,12221159 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04005198 0,12200959 ! pH reduction GO:0045851 5 5 0,000 0,04005198 0,12180825 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04005198 0,12160758 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04005198 0,12140756 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04005198 0,12120821 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04005198 0,12100951 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04005198 0,12081146 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04005198 0,12061405 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04005198 0,12041729 ! adrenal gland development GO:0030325 5 5 0,000 0,04005198 0,12022117 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04005198 0,12002569 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04005198 0,11983084 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04005198 0,11963663 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04005198 0,11944304 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04005198 0,11925008 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04005198 0,11905774 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04005198 0,11886602 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04005198 0,11867492 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04005198 0,11848443 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04005198 0,11829455 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04005198 0,11810528 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04005198 0,11791661 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04005198 0,11772855 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04005198 0,11754108 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04005198 0,11735421 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04005198 0,11716794 ! response to ATP GO:0033198 5 5 0,000 0,04005198 0,11698225 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04005198 0,11679715 ! regulation of appetite GO:0032098 5 5 0,000 0,04005198 0,11661264 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04005198 0,11642871 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04005198 0,11624535 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,04005198 0,11606258 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04005198 0,11588038 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04005198 0,11569874 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04005198 0,11551768 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04005198 0,11533719 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04005198 0,11515725 ! retinol metabolic process GO:0042572 5 5 0,000 0,04005198 0,11497788 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04005198 0,11479907 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04005198 0,11462081 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04005198 0,1144431 ! parturition GO:0007567 5 5 0,000 0,04005198 0,11426594 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04005198 0,11408933 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,04005198 0,11391327 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04005198 0,11373775 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04005198 0,11356277 ! protein heterooligomerization GO:0051291 5 5 0,000 0,04005198 0,11338832 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04005198 0,11321442 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04005198 0,11304104 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04005198 0,11286819 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04005198 0,11269588 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04005198 0,11252408 ! interaction with symbiont GO:0051702 5 5 0,000 0,04005198 0,11235281 ! cellular extravasation GO:0045123 5 5 0,000 0,04005198 0,11218207 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04005198 0,11201183 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04005198 0,11184212 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04005198 0,11167292 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04005198 0,11150423 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04005198 0,11133605 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04005198 0,11116837 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04005198 0,1110012 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04005198 0,11083453 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04005198 0,11066836 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04005198 0,11050269 ! neuron recognition GO:0008038 5 5 0,000 0,04005198 0,11033752 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04005198 0,11017283 ! hair follicle maturation GO:0048820 5 5 0,000 0,04005198 0,11000864 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04005198 0,10984494 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04005198 0,10968172 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04005198 0,10951899 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04005198 0,10935674 ! postreplication repair GO:0006301 5 5 0,000 0,04005198 0,10919497 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,04005198 0,10903368 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,04005198 0,10887286 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04005198 0,10871252 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04005198 0,10855265 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04005198 0,10839324 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04005198 0,10823431 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04005198 0,10807584 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04005198 0,10791783 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04005198 0,10776029 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,04005198 0,10760321 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04005198 0,10744658 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04005198 0,10729041 ! sterol catabolic process GO:0016127 5 5 0,000 0,04005198 0,10713469 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04005198 0,10697942 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04005198 0,1068246 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04005198 0,10667023 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04005198 0,1065163 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04005198 0,10636282 ! zymogen activation GO:0031638 5 5 0,000 0,04005198 0,10620978 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04005198 0,10605718 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04005198 0,10590502 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,04005198 0,10575329 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,04005198 0,105602 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04005198 0,10545114 ! nucleosome positioning GO:0016584 5 5 0,000 0,04005198 0,10530071 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04005198 0,10515071 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04005198 0,10500114 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04005198 0,10485199 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04005198 0,10470326 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04005198 0,10455496 ! NADPH regeneration GO:0006740 5 5 0,000 0,04005198 0,10440707 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,04005198 0,1042596 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04005198 0,10411255 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04005198 0,10396591 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04005198 0,10381969 GO:0050879|multicellular organismal movement, ! sarcomere organization GO:0045214 5 5 0,000 0,04005198 0,10367388 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04005198 0,10352847 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04005198 0,10338347 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04005198 0,10323888 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04005198 0,10309469 GO:0045622|regulation of T-helper cell differentiation, ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04005198 0,10295091 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04005198 0,10280752 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04005198 0,10266453 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04005198 0,10252194 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04005198 0,10237975 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04005198 0,10223795 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04005198 0,10209654 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04005198 0,10195552 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04005198 0,1018149 ! ATP catabolic process GO:0006200 5 5 0,000 0,04005198 0,10167465 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04005198 0,1015348 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04005198 0,10139533 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04005198 0,10125624 ! embryonic gut development GO:0048566 5 5 0,000 0,04005198 0,10111753 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04005198 0,10097921 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04005198 0,10084126 ! activation of innate immune response GO:0002218 5 5 0,000 0,04005198 0,10070368 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,04005198 0,10056648 ! catecholamine transport GO:0051937 5 5 0,000 0,04005198 0,10042966 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04005198 0,10029321 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04005198 0,10015712 ! muscle adaptation GO:0043500 5 5 0,000 0,04005198 0,10002141 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04005198 0,09988606 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04005198 0,09975108 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04005198 0,09961646 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04005198 0,09948221 ! defense response to fungus GO:0050832 5 5 0,000 0,04005198 0,09934832 ! lysogeny GO:0030069 5 5 0,000 0,04005198 0,09921478 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04005198 0,09908161 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,04005198 0,09894879 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04005198 0,09881633 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04005198 0,09868422 ! mitochondrion localization GO:0051646 5 5 0,000 0,04005198 0,09855247 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04005198 0,09842107 ! regulation of response to stress GO:0080134 97 94 2,000 0,04069508 0,09986822 ! pattern specification process GO:0007389 96 94 2,000 0,04069508 0,09973542 ! epidermis development GO:0008544 94 94 2,000 0,04069508 0,09960296 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,04167031 0,10185462 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,04358291 0,10638847 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 1,000 0,04358291 0,10624774 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,04514672 0,10991466 ! blood circulation GO:0008015 99 98 2,000 0,04514672 0,10976965 GO:0003013|circulatory system process, ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,04552783 0,11055046 ! protein ubiquitination GO:0016567 43 42 1,000 0,04552783 0,11040499 ! response to protein stimulus GO:0051789 42 42 1,000 0,04552783 0,11025992 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,04552783 0,11011522 ! anti-apoptosis GO:0006916 100 99 2,000 0,04629624 0,11182696 ! ectoderm development GO:0007398 99 99 2,000 0,04629624 0,11168059 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,0474603 0,11433899 ! response to other organism GO:0051707 101 100 2,000 0,0474603 0,11418972 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,04750446 0,11414697 ! mitochondrion organization GO:0007005 44 43 1,000 0,04750446 0,11399834 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,04750446 0,1138501 ! axon extension GO:0048675 7 6 0,000 0,04787119 0,11458001 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04787119 0,1144314 ! tRNA modification GO:0006400 6 6 0,000 0,04787119 0,11428317 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04787119 0,11413533 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04787119 0,11398787 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04787119 0,11384079 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04787119 0,11369408 ! virus-host interaction GO:0019048 6 6 0,000 0,04787119 0,11354776 ! regulation of S phase GO:0033261 6 6 0,000 0,04787119 0,11340181 ! myotube differentiation GO:0014902 6 6 0,000 0,04787119 0,11325624 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04787119 0,11311104 ! bone remodeling GO:0046849 6 6 0,000 0,04787119 0,11296621 ! N-glycan processing GO:0006491 6 6 0,000 0,04787119 0,11282175 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04787119 0,11267766 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04787119 0,11253394 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04787119 0,11239058 ! RNA methylation GO:0001510 6 6 0,000 0,04787119 0,11224759 ! cartilage condensation GO:0001502 7 6 0,000 0,04787119 0,11210497 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04787119 0,1119627 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04787119 0,1118208 GO:0050927|positive regulation of positive chemotaxis, ! artery development GO:0060840 6 6 0,000 0,04787119 0,11167925 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04787119 0,11153806 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04787119 0,11139723 ! androgen metabolic process GO:0008209 6 6 0,000 0,04787119 0,11125676 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04787119 0,11111664 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04787119 0,11097687 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04787119 0,11083745 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04787119 0,11069838 ! pathogenesis GO:0009405 6 6 0,000 0,04787119 0,11055966 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04787119 0,11042129 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04787119 0,11028326 ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04787119 0,11014558 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04787119 0,11000824 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04787119 0,10987124 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04787119 0,10973459 ! arginine metabolic process GO:0006525 6 6 0,000 0,04787119 0,10959827 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04787119 0,10946229 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04787119 0,10932665 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04787119 0,10919135 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04787119 0,10905638 GO:0010833|telomere maintenance via telomere lengthening, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04787119 0,10892174 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04787119 0,10878743 ! V(D)J recombination GO:0033151 6 6 0,000 0,04787119 0,10865346 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04787119 0,10851981 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04787119 0,1083865 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04787119 0,10825351 ! regulation of heart rate GO:0002027 6 6 0,000 0,04787119 0,10812084 ! lipid digestion GO:0044241 6 6 0,000 0,04787119 0,10798851 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04787119 0,10785649 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04787119 0,1077248 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04787119 0,10759343 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04787119 0,10746237 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04787119 0,10733164 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04787119 0,10720123 ! ruffle organization GO:0031529 6 6 0,000 0,04787119 0,10707113 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04787119 0,10694134 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04787119 0,10681187 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04787119 0,10668272 ! L-amino acid transport GO:0015807 6 6 0,000 0,04787119 0,10655388 ! bone mineralization GO:0030282 6 6 0,000 0,04787119 0,10642534 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04787119 0,10629712 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04787119 0,1061692 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,04787119 0,1060416 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04787119 0,1059143 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04787119 0,1057873 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,04787119 0,10566061 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04787119 0,10553422 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04787119 0,10540813 ! regulation of organ growth GO:0046620 6 6 0,000 0,04787119 0,10528235 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04787119 0,10515686 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04787119 0,10503168 ! response to dsRNA GO:0043331 6 6 0,000 0,04787119 0,10490679 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04787119 0,1047822 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04787119 0,1046579 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04787119 0,1045339 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04787119 0,10441019 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04787119 0,10428677 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04787119 0,10416365 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04787119 0,10404081 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04787119 0,10391827 ! erythrocyte development GO:0048821 6 6 0,000 0,04787119 0,10379601 ! renal water homeostasis GO:0003091 6 6 0,000 0,04787119 0,10367404 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04787119 0,10355236 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04787119 0,10343096 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04787119 0,10330985 ! ribosome assembly GO:0042255 6 6 0,000 0,04787119 0,10318902 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04787119 0,10306847 ! diencephalon development GO:0021536 6 6 0,000 0,04787119 0,1029482 ! fucose catabolic process GO:0019317 6 6 0,000 0,04787119 0,10282822 GO:0042355|L-fucose catabolic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04787119 0,10270851 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04787119 0,10258908 ! regulation of cell division GO:0051302 6 6 0,000 0,04787119 0,10246993 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04787119 0,10235105 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04787119 0,10223245 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04787119 0,10211413 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04787119 0,10199608 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04787119 0,1018783 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04787119 0,10176079 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04787119 0,10164356 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04787119 0,10152659 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04787119 0,10140989 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04787119 0,10129347 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04787119 0,1011773 ! lymph node development GO:0048535 6 6 0,000 0,04787119 0,10106141 ! organic cation transport GO:0015695 6 6 0,000 0,04787119 0,10094578 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04787119 0,10083041 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04787119 0,10071531 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04787119 0,10060047 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04787119 0,10048589 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04787119 0,10037157 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04787119 0,10025751 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04787119 0,10014371 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04787119 0,10003017 ! alditol metabolic process GO:0019400 6 6 0,000 0,04787119 0,09991688 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04787119 0,09980386 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04787119 0,09969108 ! regulation of embryonic development GO:0045995 6 6 0,000 0,04787119 0,09957857 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04787119 0,0994663 ! localization within membrane GO:0051668 6 6 0,000 0,04787119 0,09935429 ! humoral immune response GO:0006959 44 44 1,000 0,04951217 0,10264447 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,04951217 0,10252914 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,04951217 0,10241407 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,05155035 0,10651041 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,05155035 0,10639114 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,05155035 0,10627214 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,05361837 0,11041191 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,05361837 0,11028868 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,05361837 0,11016573 ! respiratory burst GO:0045730 7 7 0,000 0,05562784 0,11416717 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,05562784 0,11404017 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,05562784 0,11391346 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,05562784 0,11378703 ! regulation of chemokine production GO:0032642 7 7 0,000 0,05562784 0,11366088 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,05562784 0,11353501 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,05562784 0,11340942 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,05562784 0,1132841 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,05562784 0,11315907 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,05562784 0,11303431 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,05562784 0,11290982 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,05562784 0,1127856 ! axis specification GO:0009798 7 7 0,000 0,05562784 0,11266166 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,05562784 0,112538 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,05562784 0,1124146 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,05562784 0,11229147 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,05562784 0,11216862 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,05562784 0,11204603 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,05562784 0,11192371 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,05562784 0,11180165 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,05562784 0,11167986 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,05562784 0,11155834 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,05562784 0,11143708 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,05562784 0,11131609 ! protein targeting to ER GO:0045047 8 7 0,000 0,05562784 0,11119535 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,05562784 0,11107488 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,05562784 0,11095467 ! endoderm development GO:0007492 7 7 0,000 0,05562784 0,11083472 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,05562784 0,11071503 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,05562784 0,11059559 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,05562784 0,11047642 ! response to hexose stimulus GO:0009746 7 7 0,000 0,05562784 0,1103575 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,05562784 0,11023883 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,05562784 0,11012042 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,05562784 0,11000227 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,05562784 0,10988437 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,05562784 0,10976672 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,05562784 0,10964932 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,05562784 0,10953217 ! response to X-ray GO:0010165 7 7 0,000 0,05562784 0,10941528 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,05562784 0,10929863 ! UV protection GO:0009650 7 7 0,000 0,05562784 0,10918223 ! DNA integration GO:0015074 7 7 0,000 0,05562784 0,10906608 ! myofibril assembly GO:0030239 7 7 0,000 0,05562784 0,10895018 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,05562784 0,10883452 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,05562784 0,1087191 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,05562784 0,10860394 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,05562784 0,10848901 GO:0030204|chondroitin sulfate metabolic process, ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,05562784 0,10837433 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,05562784 0,10825989 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,05562784 0,10814569 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,05562784 0,10803173 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,05562784 0,10791802 ! axon cargo transport GO:0008088 7 7 0,000 0,05562784 0,10780454 ! eating behavior GO:0042755 7 7 0,000 0,05562784 0,1076913 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,05562784 0,10757829 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,05562784 0,10746553 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,05562784 0,107353 ! cranial nerve development GO:0021545 7 7 0,000 0,05562784 0,10724071 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,05562784 0,10712865 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,05562784 0,10701682 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,05562784 0,10690523 ! autonomic nervous system development GO:0048483 7 7 0,000 0,05562784 0,10679387 ! intracellular lipid transport GO:0032365 7 7 0,000 0,05562784 0,10668274 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,05562784 0,10657184 ! platelet activation GO:0030168 8 7 0,000 0,05562784 0,10646118 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,05562784 0,10635074 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,05562784 0,10624053 ! natural killer cell activation GO:0030101 7 7 0,000 0,05562784 0,10613055 ! NADP metabolic process GO:0006739 7 7 0,000 0,05562784 0,1060208 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,05562784 0,10591128 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,05562784 0,10580198 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,05562784 0,1056929 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,05562784 0,10558405 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,05562784 0,10547543 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,05562784 0,10536702 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,05562784 0,10525884 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,05562784 0,10515089 ! cell-cell recognition GO:0009988 8 7 0,000 0,05562784 0,10504315 ! hormone catabolic process GO:0042447 7 7 0,000 0,05562784 0,10493563 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,05562784 0,10482834 ! oxygen transport GO:0015671 7 7 0,000 0,05562784 0,10472126 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,05562784 0,1046144 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,05562784 0,10450776 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,05562784 0,10440134 ! regulation of axon extension GO:0030516 7 7 0,000 0,05562784 0,10429513 ! cell killing GO:0001906 7 7 0,000 0,05562784 0,10418914 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,05562784 0,10408337 ! adult feeding behavior GO:0008343 7 7 0,000 0,05562784 0,1039778 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,05562784 0,10387246 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,05562784 0,10376732 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,05562784 0,1036624 ! response to cold GO:0009409 7 7 0,000 0,05562784 0,10355769 ! amine transport GO:0015837 47 47 1,000 0,05571565 0,10361649 ! rhythmic process GO:0048511 47 47 1,000 0,05571565 0,10351204 ! calcium ion transport GO:0006816 48 48 1,000 0,05784159 0,10735352 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,05784159 0,10724552 ! DNA recombination GO:0006310 48 48 1,000 0,05784159 0,10713774 ! ossification GO:0001503 50 49 1,000 0,0599956 0,11101595 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 1,000 0,0599956 0,1109046 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,0599956 0,11079347 ! divalent metal ion transport GO:0070838 49 49 1,000 0,0599956 0,11068257 ! response to bacterium GO:0009617 50 49 1,000 0,0599956 0,11057188 ! regulation of ligase activity GO:0051340 50 49 1,000 0,0599956 0,11046142 ! cofactor biosynthetic process GO:0051188 49 49 1,000 0,0599956 0,11035118 ! negative regulation of transport GO:0051051 51 50 1,000 0,0621771 0,11424964 ! chromatin assembly GO:0031497 50 50 1,000 0,0621771 0,11413585 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 1,000 0,0621771 0,11402228 ! nitrogen compound catabolic process GO:0044270 51 50 1,000 0,0621771 0,11390894 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,0621771 0,11379582 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,0621771 0,11368293 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,06332242 0,11566226 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,06332242 0,11554775 ! positive regulation of translation GO:0045727 8 8 0,000 0,06332242 0,11543346 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,06332242 0,11531939 ! superoxide anion generation GO:0042554 8 8 0,000 0,06332242 0,11520555 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,06332242 0,11509194 ! cGMP metabolic process GO:0046068 8 8 0,000 0,06332242 0,11497855 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,06332242 0,11486538 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,06332242 0,11475243 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,06332242 0,11463971 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,06332242 0,11452721 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,06332242 0,11441493 ! zinc ion transport GO:0006829 8 8 0,000 0,06332242 0,11430286 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,06332242 0,11419102 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,06332242 0,1140794 ! lipid localization GO:0010876 8 8 0,000 0,06332242 0,11396799 GO:0019915|lipid storage, ! response to cAMP GO:0051591 8 8 0,000 0,06332242 0,1138568 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,06332242 0,11374583 GO:0048200|Golgi transport vesicle coating, ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,06332242 0,11363508 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,06332242 0,11352454 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,06332242 0,11341421 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,06332242 0,1133041 ! sensory perception of taste GO:0050909 8 8 0,000 0,06332242 0,1131942 ! organelle fusion GO:0048284 8 8 0,000 0,06332242 0,11308452 ! pancreas development GO:0031016 8 8 0,000 0,06332242 0,11297505 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,06332242 0,11286579 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,06332242 0,11275674 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,06332242 0,1126479 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,06332242 0,11253927 ! sperm motility GO:0030317 8 8 0,000 0,06332242 0,11243085 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,06332242 0,11232264 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,06332242 0,11221464 GO:0032392|DNA geometric change, ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,06332242 0,11210684 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,06332242 0,11199926 ! Golgi organization GO:0007030 8 8 0,000 0,06332242 0,11189187 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,06332242 0,1117847 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,06332242 0,11167773 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,06332242 0,11157096 ! fructose metabolic process GO:0006000 8 8 0,000 0,06332242 0,1114644 ! mannose metabolic process GO:0006013 9 8 0,000 0,06332242 0,11135804 ! NAD metabolic process GO:0019674 8 8 0,000 0,06332242 0,11125188 ! sex determination GO:0007530 8 8 0,000 0,06332242 0,11114593 ! plasma membrane fusion GO:0045026 8 8 0,000 0,06332242 0,11104017 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,06332242 0,11093462 ! response to fungus GO:0009620 8 8 0,000 0,06332242 0,11082927 ! stem cell differentiation GO:0048863 8 8 0,000 0,06332242 0,11072412 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,06332242 0,11061917 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,06332242 0,11051442 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,06332242 0,11040986 ! regulation of vasodilation GO:0042312 8 8 0,000 0,06332242 0,1103055 ! vasoconstriction GO:0042310 8 8 0,000 0,06332242 0,11020134 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,06332242 0,11009738 ! muscle cell development GO:0055001 8 8 0,000 0,06332242 0,10999361 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,06332242 0,10989004 ! sensory perception of pain GO:0019233 8 8 0,000 0,06332242 0,10978666 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,06332242 0,10968348 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,06332242 0,10958049 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,06332242 0,1094777 ! chromatin silencing GO:0006342 8 8 0,000 0,06332242 0,10937509 ! tissue regeneration GO:0042246 8 8 0,000 0,06332242 0,10927268 ! salivary gland development GO:0007431 8 8 0,000 0,06332242 0,10917046 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,06332242 0,10906843 ! water homeostasis GO:0030104 8 8 0,000 0,06332242 0,1089666 ! cofactor transport GO:0051181 8 8 0,000 0,06332242 0,10886495 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,06332242 0,10876349 ! acid secretion GO:0046717 8 8 0,000 0,06332242 0,10866222 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,06332242 0,10856114 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,06332242 0,10846025 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,06332242 0,10835954 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,06332242 0,10825902 ! regulation of RNA stability GO:0043487 8 8 0,000 0,06332242 0,10815869 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,06332242 0,10805854 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,06332242 0,10795858 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,06332242 0,1078588 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,06332242 0,10775921 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,06332242 0,1076598 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,06332242 0,10756057 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,06332242 0,10746153 ! peptide hormone secretion GO:0030072 8 8 0,000 0,06332242 0,10736267 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,06332242 0,10726399 ! actin filament polymerization GO:0030041 9 8 0,000 0,06332242 0,10716549 ! peptide hormone processing GO:0016486 8 8 0,000 0,06332242 0,10706718 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,06332242 0,10696904 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,06332242 0,10687108 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,06438552 0,10856589 ! protein-DNA complex assembly GO:0065004 51 51 1,000 0,06438552 0,10846665 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,0666203 0,11212896 ! regulation of T cell activation GO:0050863 53 53 1,000 0,06888087 0,11582797 ! lactation GO:0007595 10 9 0,000 0,07095542 0,11920769 ! embryonic pattern specification GO:0009880 10 9 0,000 0,07095542 0,11909912 ! positive regulation of cell size GO:0045793 9 9 0,000 0,07095542 0,11899075 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,07095542 0,11888258 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,07095542 0,1187746 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,07095542 0,11866682 ! viral genome replication GO:0019079 9 9 0,000 0,07095542 0,11855923 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,07095542 0,11845184 ! copper ion transport GO:0006825 9 9 0,000 0,07095542 0,11834465 ! lipid phosphorylation GO:0046834 9 9 0,000 0,07095542 0,11823764 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,07095542 0,11813083 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,07095542 0,11802422 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,07095542 0,11791779 ! RNA polyadenylation GO:0043631 9 9 0,000 0,07095542 0,11781156 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,07095542 0,11770552 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,07095542 0,11759967 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,07095542 0,11749401 ! phospholipid efflux GO:0033700 9 9 0,000 0,07095542 0,11738854 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,07095542 0,11728326 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,07095542 0,11717817 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,07095542 0,11707326 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,07095542 0,11696855 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,07095542 0,11686402 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,07095542 0,11675967 ! methionine metabolic process GO:0006555 9 9 0,000 0,07095542 0,11665552 ! glutamine metabolic process GO:0006541 9 9 0,000 0,07095542 0,11655155 ! response to osmotic stress GO:0006970 9 9 0,000 0,07095542 0,11644776 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,07095542 0,11634416 ! central nervous system neuron development GO:0021954 10 9 0,000 0,07095542 0,11624074 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,07095542 0,11613751 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,07095542 0,11603446 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,07095542 0,11593159 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,07095542 0,11582891 ! L-glutamate transport GO:0015813 9 9 0,000 0,07095542 0,1157264 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,07095542 0,11562408 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,07095542 0,11552194 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,07095542 0,11541998 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,07095542 0,1153182 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,07095542 0,11521659 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,07095542 0,11511517 ! DNA replication initiation GO:0006270 9 9 0,000 0,07095542 0,11501393 ! regulation of cellular pH GO:0030641 9 9 0,000 0,07095542 0,11491286 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,07095542 0,11481197 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,07095542 0,11471126 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,07095542 0,11461072 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,07095542 0,11451036 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,07095542 0,11441018 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,07095542 0,11431017 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,07095542 0,11421034 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,07095542 0,11411068 ! purine base metabolic process GO:0006144 9 9 0,000 0,07095542 0,11401119 ! gas transport GO:0015669 9 9 0,000 0,07095542 0,11391188 ! cholesterol efflux GO:0033344 9 9 0,000 0,07095542 0,11381274 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,07095542 0,11371377 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,07095542 0,11361497 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,07095542 0,11351635 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,07095542 0,1134179 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,07095542 0,11331961 ! actin filament-based movement GO:0030048 9 9 0,000 0,07095542 0,1132215 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,07095542 0,11312356 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,0711667 0,11336234 ! response to virus GO:0009615 54 54 1,000 0,0711667 0,11326445 ! hormone metabolic process GO:0042445 55 54 1,000 0,0711667 0,11316672 ! sulfur metabolic process GO:0006790 55 54 1,000 0,0711667 0,11306916 ! nucleosome organization GO:0034728 55 55 1,000 0,07347723 0,11663956 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,07347723 0,11653919 ! in utero embryonic development GO:0001701 55 55 1,000 0,07347723 0,11643898 ! regulation of nervous system development GO:0051960 57 56 1,000 0,07581193 0,12003555 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07852731 0,12422819 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07852731 0,12412165 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,07852731 0,12401529 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07852731 0,12390911 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,07852731 0,12380311 ! neuron maturation GO:0042551 10 10 0,000 0,07852731 0,1236973 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07852731 0,12359166 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07852731 0,12348621 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,07852731 0,12338094 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,07852731 0,12327584 ! hormone secretion GO:0046879 10 10 0,000 0,07852731 0,12317093 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07852731 0,12306619 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07852731 0,12296163 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,07852731 0,12285725 ! inositol metabolic process GO:0006020 10 10 0,000 0,07852731 0,12275304 ! cAMP metabolic process GO:0046058 10 10 0,000 0,07852731 0,12264902 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07852731 0,12254516 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07852731 0,12244149 ! glial cell development GO:0021782 10 10 0,000 0,07852731 0,12233799 ! phototransduction GO:0007602 11 10 0,000 0,07852731 0,12223466 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,07852731 0,12213151 ! myoblast differentiation GO:0045445 10 10 0,000 0,07852731 0,12202853 ! centrosome cycle GO:0007098 10 10 0,000 0,07852731 0,12192573 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07852731 0,1218231 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07852731 0,12172064 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07852731 0,12161835 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07852731 0,12151624 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,07852731 0,12141429 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07852731 0,12131252 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07852731 0,12121092 ! plasma membrane organization GO:0007009 10 10 0,000 0,07852731 0,12110949 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,07852731 0,12100823 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,07852731 0,12090713 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07852731 0,12080621 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07852731 0,12070545 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,07852731 0,12060487 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,07852731 0,12050444 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,07852731 0,12040419 ! embryo implantation GO:0007566 11 10 0,000 0,07852731 0,12030411 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07852731 0,12020418 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07852731 0,12010443 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07852731 0,12000484 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,07852731 0,11990542 ! protein export from nucleus GO:0006611 10 10 0,000 0,07852731 0,11980616 ! negative regulation of immune response GO:0050777 10 10 0,000 0,07852731 0,11970706 ! cytolysis GO:0019835 10 10 0,000 0,07852731 0,11960813 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07852731 0,11950936 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,07852731 0,11941076 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,07852731 0,11931232 ! histone deacetylation GO:0016575 10 10 0,000 0,07852731 0,11921403 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07852731 0,11911592 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,07852731 0,11901796 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07852731 0,11892016 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07852731 0,11882253 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07852731 0,11872505 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07852731 0,11862774 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07852731 0,11853058 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07852731 0,11843358 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07852731 0,11833674 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07852731 0,11824006 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,07852731 0,11814354 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,07852731 0,11804718 ! nerve development GO:0021675 10 10 0,000 0,07852731 0,11795097 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,07852731 0,11785492 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,07852731 0,11775902 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,07852731 0,11766328 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07852731 0,1175677 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,07852731 0,11747227 ! dephosphorylation GO:0016311 60 59 1,000 0,08295576 0,12399633 ! regulation of cell development GO:0060284 60 59 1,000 0,08295576 0,12389584 ! immune effector process GO:0002252 59 59 1,000 0,08295576 0,12379552 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,0853819 0,12731298 ! protein secretion GO:0009306 11 11 0,000 0,08603859 0,12818846 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,08603859 0,12808491 ! negative regulation of defense response GO:0031348 11 11 0,000 0,08603859 0,12798153 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,08603859 0,12787832 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,08603859 0,12777528 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,08603859 0,1276724 ! skin development GO:0043588 11 11 0,000 0,08603859 0,12756969 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,08603859 0,12746714 ! microtubule-based transport GO:0010970 11 11 0,000 0,08603859 0,12736476 ! endothelial cell migration GO:0043542 11 11 0,000 0,08603859 0,12726254 ! peroxisomal transport GO:0043574 11 11 0,000 0,08603859 0,12716048 ! protein amino acid methylation GO:0006479 11 11 0,000 0,08603859 0,12705859 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,08603859 0,12695686 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,08603859 0,1268553 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,08603859 0,12675389 ! T cell proliferation GO:0042098 11 11 0,000 0,08603859 0,12665265 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,08603859 0,12655157 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,08603859 0,12645065 ! spinal cord development GO:0021510 11 11 0,000 0,08603859 0,1263499 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,08603859 0,1262493 ! smooth muscle contraction GO:0006939 11 11 0,000 0,08603859 0,12614886 ! cellular response to starvation GO:0009267 11 11 0,000 0,08603859 0,12604859 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,08603859 0,12594847 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,08603859 0,12584851 ! digestive system process GO:0022600 11 11 0,000 0,08603859 0,12574871 ! mitotic spindle organization GO:0007052 11 11 0,000 0,08603859 0,12564907 ! fucose metabolic process GO:0006004 11 11 0,000 0,08603859 0,12554958 ! membrane budding GO:0006900 11 11 0,000 0,08603859 0,12545025 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,08603859 0,12535108 ! monoamine transport GO:0015844 11 11 0,000 0,08603859 0,12525207 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,08603859 0,12515321 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,08603859 0,12505451 ! body fluid secretion GO:0007589 11 11 0,000 0,08603859 0,12495597 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,08603859 0,12485758 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,08603859 0,12475934 ! intermediate filament-based process GO:0045103 11 11 0,000 0,08603859 0,12466126 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,08603859 0,12456333 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,08603859 0,12446556 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,08603859 0,12436794 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,08603859 0,12427047 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,08603859 0,12417316 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,08603859 0,12407599 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,08603859 0,12397898 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,08603859 0,12388213 ! muscle maintenance GO:0046716 12 11 0,000 0,08603859 0,12378542 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,08603859 0,12368886 ! steroid catabolic process GO:0006706 11 11 0,000 0,08603859 0,12359246 ! endocrine process GO:0050886 11 11 0,000 0,08603859 0,1234962 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,08603859 0,12340009 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,08603859 0,12330414 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,08782962 0,12577311 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! lipid transport GO:0006869 62 62 1,000 0,09029844 0,12920809 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 1,000 0,09029844 0,12910785 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,09029844 0,12900777 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,09029844 0,12890784 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,09029844 0,12880806 ! regulation of secretion GO:0051046 65 63 1,000 0,09278785 0,13225677 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 1,000 0,09278785 0,13215456 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 1,000 0,09278785 0,13205251 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,09348972 0,13294874 ! translational initiation GO:0006413 12 12 0,000 0,09348972 0,13284623 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,09348972 0,13274388 ! initiation of viral infection GO:0019059 12 12 0,000 0,09348972 0,13264169 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,09348972 0,13253966 ! iron ion transport GO:0006826 13 12 0,000 0,09348972 0,13243779 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,09348972 0,13233607 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,09348972 0,13223451 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,09348972 0,1321331 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,09348972 0,13203185 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,09348972 0,13193075 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,09348972 0,13182981 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,09348972 0,13172902 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,09348972 0,13162839 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,09348972 0,13152791 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,09348972 0,13142758 ! actomyosin structure organization GO:0031032 12 12 0,000 0,09348972 0,13132741 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,09348972 0,13122739 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,09348972 0,13112752 ! retinoid metabolic process GO:0001523 12 12 0,000 0,09348972 0,1310278 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,09348972 0,13092824 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,09348972 0,13082882 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,09348972 0,13072956 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,09348972 0,13063045 ! acute-phase response GO:0006953 12 12 0,000 0,09348972 0,13053149 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,09348972 0,13043267 ! vacuolar transport GO:0007034 12 12 0,000 0,09348972 0,13033401 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,09348972 0,1302355 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,09348972 0,13013713 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,09348972 0,13003891 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,09348972 0,12994085 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,09348972 0,12984292 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,09348972 0,12974515 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,09348972 0,12964753 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,09348972 0,12955005 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,09348972 0,12945271 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,09348972 0,12935553 ! cell fate determination GO:0001709 12 12 0,000 0,09348972 0,12925849 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,09348972 0,12916159 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,09348972 0,12906484 ! detection of light stimulus GO:0009583 13 12 0,000 0,09348972 0,12896823 ! synaptogenesis GO:0007416 12 12 0,000 0,09348972 0,12887177 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,09348972 0,12877546 ! hormone transport GO:0009914 12 12 0,000 0,09348972 0,12867928 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,09348972 0,12858325 ! heme biosynthetic process GO:0006783 12 12 0,000 0,09348972 0,12848737 ! spermatid differentiation GO:0048515 13 12 0,000 0,09348972 0,12839163 GO:0007286|spermatid development, ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,09348972 0,12829602 ! neural tube closure GO:0001843 13 12 0,000 0,09348972 0,12820057 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,09348972 0,12810525 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,09348972 0,12801008 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,09348972 0,12791504 ! regulation of hormone levels GO:0010817 66 65 1,000 0,09782653 0,13374948 ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 0,10037486 0,13713185 ! DNA packaging GO:0006323 66 66 1,000 0,10037486 0,13703027 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,10037486 0,13692884 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,10088119 0,13751777 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,10088119 0,13741613 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,10088119 0,13731465 ! gluconeogenesis GO:0006094 13 13 0,000 0,10088119 0,13721331 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,10088119 0,13711212 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,10088119 0,13701108 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,10088119 0,13691018 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,10088119 0,13680944 ! keratinization GO:0031424 13 13 0,000 0,10088119 0,13670885 ! patterning of blood vessels GO:0001569 13 13 0,000 0,10088119 0,1366084 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,10088119 0,1365081 ! regulation of innate immune response GO:0045088 13 13 0,000 0,10088119 0,13640795 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,10088119 0,13630794 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,10088119 0,13620808 ! autophagy GO:0006914 13 13 0,000 0,10088119 0,13610837 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,10088119 0,1360088 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,10088119 0,13590938 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,10088119 0,1358101 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,10088119 0,13571097 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,10088119 0,13561198 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,10088119 0,13551314 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,10088119 0,13541444 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,10088119 0,13531589 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,10088119 0,13521748 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,10088119 0,13511921 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,10088119 0,13502108 ! vasodilation GO:0042311 14 13 0,000 0,10088119 0,1349231 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,10088119 0,13482526 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,10088119 0,13472756 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,10088119 0,13463 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,10088119 0,13453258 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,10088119 0,13443531 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,10088119 0,13433817 ! immunoglobulin production GO:0002377 13 13 0,000 0,10088119 0,13424118 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,10088119 0,13414432 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,10088119 0,13404761 ! cell-cell junction organization GO:0045216 13 13 0,000 0,10088119 0,13395103 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,10088119 0,13385459 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,10088119 0,13375829 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,10088119 0,13366213 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,10088119 0,13356611 GO:0019370|leukotriene biosynthetic process, ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,10088119 0,13347023 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,10088119 0,13337448 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,10088119 0,13327887 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,10088119 0,1331834 ! telomere organization GO:0032200 13 13 0,000 0,10088119 0,13308807 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,10088119 0,13299287 ! regulation of amine transport GO:0051952 13 13 0,000 0,10088119 0,13289781 ! protein tetramerization GO:0051262 13 13 0,000 0,10088119 0,13280288 ! muscle contraction GO:0006936 67 67 1,000 0,10294188 0,13541891 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,10552715 0,13872078 ! sensory perception of sound GO:0007605 71 69 1,000 0,1081302 0,14204131 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,1081302 0,14194014 ! neuron fate commitment GO:0048663 14 14 0,000 0,10821345 0,14194832 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,10821345 0,14184736 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,10821345 0,14174655 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,10821345 0,14164587 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,10821345 0,14154534 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,10821345 0,14144496 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,10821345 0,14134471 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,10821345 0,14124461 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,10821345 0,14114465 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,10821345 0,14104483 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,10821345 0,14094515 ! vesicle docking GO:0048278 14 14 0,000 0,10821345 0,14084562 ! superoxide metabolic process GO:0006801 15 14 0,000 0,10821345 0,14074622 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,10821345 0,14064696 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,10821345 0,14054784 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,10821345 0,14044887 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,10821345 0,14035003 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,10821345 0,14025133 GO:0033189|response to vitamin A, ! lysosome organization GO:0007040 14 14 0,000 0,10821345 0,14015277 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,10821345 0,14005435 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,10821345 0,13995606 ! peptide transport GO:0015833 14 14 0,000 0,10821345 0,13985792 ! primary neural tube formation GO:0014020 15 14 0,000 0,10821345 0,13975991 ! peptide cross-linking GO:0018149 14 14 0,000 0,10821345 0,13966204 ! regulation of behavior GO:0050795 14 14 0,000 0,10821345 0,1395643 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,10821345 0,13946671 ! base-excision repair GO:0006284 14 14 0,000 0,10821345 0,13936925 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,10821345 0,13927192 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,10821345 0,13917473 ! formation of primary germ layer GO:0001704 14 14 0,000 0,10821345 0,13907768 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,10821345 0,13898076 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,10821345 0,13888398 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,10821345 0,13878733 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,10821345 0,13869081 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,10821345 0,13859443 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,10821345 0,13849819 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,10821345 0,13840208 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,11075059 0,14154877 GO:0016053|organic acid biosynthetic process, ! calcium ion homeostasis GO:0055074 71 71 1,000 0,11338787 0,14481902 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 1,000 0,11338787 0,14471873 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,11548698 0,14729585 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,11548698 0,14719399 ! positive regulation of ossification GO:0045778 15 15 0,000 0,11548698 0,14709226 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,11548698 0,14699068 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,11548698 0,14688924 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,11548698 0,14678793 ! response to vitamin GO:0033273 15 15 0,000 0,11548698 0,14668677 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,11548698 0,14658575 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,11548698 0,14648486 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,11548698 0,14638412 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,11548698 0,14628351 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,11548698 0,14618304 ! heme metabolic process GO:0042168 15 15 0,000 0,11548698 0,14608271 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,11548698 0,14598251 ! chromosome condensation GO:0030261 15 15 0,000 0,11548698 0,14588246 ! response to starvation GO:0042594 15 15 0,000 0,11548698 0,14578254 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,11548698 0,14568275 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,11548698 0,14558311 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,11548698 0,1454836 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,11548698 0,14538422 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,11548698 0,14528499 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,11548698 0,14518588 ! phospholipid transport GO:0015914 15 15 0,000 0,11548698 0,14508691 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,11548698 0,14498808 ! glutathione metabolic process GO:0006749 16 15 0,000 0,11548698 0,14488938 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,11548698 0,14479082 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,11548698 0,14469239 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,11548698 0,14459409 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,11548698 0,14449593 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,11548698 0,1443979 ! muscle system process GO:0003012 72 72 1,000 0,11604162 0,14499302 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,12139679 0,15158149 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,12270224 0,1531078 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,12270224 0,15300421 ! circadian rhythm GO:0007623 16 16 0,000 0,12270224 0,15290076 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,12270224 0,15279745 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,12270224 0,15269427 ! vacuole organization GO:0007033 16 16 0,000 0,12270224 0,15259124 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,12270224 0,15248835 ! vesicle targeting GO:0006903 17 16 0,000 0,12270224 0,15238559 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,12270224 0,15228298 ! iron ion homeostasis GO:0055072 16 16 0,000 0,12270224 0,1521805 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,12270224 0,15207816 ! pentose metabolic process GO:0019321 16 16 0,000 0,12270224 0,15197595 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,12270224 0,15187389 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,12270224 0,15177196 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,12270224 0,15167017 ! cofactor catabolic process GO:0051187 16 16 0,000 0,12270224 0,15156851 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,12270224 0,15146699 ! polyol metabolic process GO:0019751 16 16 0,000 0,12270224 0,15136561 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,12270224 0,15126436 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,12270224 0,15116325 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,12270224 0,15106227 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,12270224 0,15096143 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,12270224 0,15086072 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,12270224 0,15076015 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,12270224 0,15065971 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,12409736 0,15227126 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,12954242 0,15884677 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,12985968 0,15912991 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,12985968 0,15902418 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,12985968 0,15891858 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,12985968 0,15881313 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,12985968 0,15870781 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,12985968 0,15860264 ! sensory perception of smell GO:0007608 17 17 0,000 0,12985968 0,15849761 ! tissue remodeling GO:0048771 17 17 0,000 0,12985968 0,15839271 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,12985968 0,15828795 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,12985968 0,15818333 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,12985968 0,15807885 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,12985968 0,15797451 ! neural crest cell development GO:0014032 19 17 0,000 0,12985968 0,15787031 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 18 17 0,000 0,12985968 0,15776624 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,12985968 0,15766231 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,12985968 0,15755851 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,12985968 0,15745486 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,12985968 0,15735134 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,12985968 0,15724795 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,12985968 0,1571447 ! adult locomotory behavior GO:0008344 17 17 0,000 0,12985968 0,15704159 ! embryonic organ development GO:0048568 17 17 0,000 0,12985968 0,15693861 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,12985968 0,15683577 ! liver development GO:0001889 17 17 0,000 0,12985968 0,15673306 ! gene silencing GO:0016458 17 17 0,000 0,12985968 0,15663049 ! metal ion homeostasis GO:0055065 78 78 1,000 0,1322861 0,15945277 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,13695976 0,16497832 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,13695976 0,16487056 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,13695976 0,16476295 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,13695976 0,16465547 ! membrane docking GO:0022406 18 18 0,000 0,13695976 0,16454813 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,13695976 0,16444093 ! response to calcium ion GO:0051592 18 18 0,000 0,13695976 0,16433388 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,13695976 0,16422696 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,13695976 0,16412018 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,13695976 0,16401354 ! striated muscle contraction GO:0006941 18 18 0,000 0,13695976 0,16390703 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,13695976 0,16380067 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,13695976 0,16369444 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,13695976 0,16358836 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,13695976 0,16348241 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,13695976 0,16337659 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,13695976 0,16327091 ! BMP signaling pathway GO:0030509 18 18 0,000 0,13695976 0,16316537 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,13695976 0,16305997 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,13695976 0,1629547 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,13695976 0,16284957 ! lymphocyte activation GO:0046649 82 81 1,000 0,14059699 0,16706657 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,14400293 0,17100348 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,14400293 0,17089337 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,14400293 0,1707834 ! glial cell differentiation GO:0010001 19 19 0,000 0,14400293 0,17067357 ! regulation of pH GO:0006885 19 19 0,000 0,14400293 0,17056388 ! feeding behavior GO:0007631 19 19 0,000 0,14400293 0,17045434 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,14400293 0,17034493 ! peroxisome organization GO:0007031 19 19 0,000 0,14400293 0,17023566 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,14400293 0,17012654 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,14400293 0,17001755 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,14400293 0,16990871 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,14400293 0,1698 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,14400293 0,16969143 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,14400293 0,169583 ! eye morphogenesis GO:0048592 19 19 0,000 0,14400293 0,16947471 ! regulation of cell shape GO:0008360 21 19 0,000 0,14400293 0,16936656 ! vesicle localization GO:0051648 20 19 0,000 0,14400293 0,16925855 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,14620027 0,17173173 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,14620027 0,17162235 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,15098964 0,17713171 ! organic ether metabolic process GO:0018904 20 20 0,000 0,15098964 0,17701903 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,15098964 0,17690649 ! nucleus organization GO:0006997 20 20 0,000 0,15098964 0,1767941 ! phagocytosis GO:0006909 21 20 0,000 0,15098964 0,17668185 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,15098964 0,17656974 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,15098964 0,17645778 ! protein targeting to membrane GO:0006612 22 20 0,000 0,15098964 0,17634595 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,15098964 0,17623427 ! chromatin remodeling GO:0006338 20 20 0,000 0,15098964 0,17612273 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,15098964 0,17601133 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,15098964 0,17590007 ! RNA modification GO:0009451 20 20 0,000 0,15098964 0,17578895 ! single fertilization GO:0007338 21 20 0,000 0,15098964 0,17567798 ! regulation of B cell activation GO:0050864 20 20 0,000 0,15098964 0,17556714 ! mRNA catabolic process GO:0006402 21 21 0,000 0,15792034 0,18351021 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,15792034 0,18339457 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,15792034 0,18327909 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,15792034 0,18316374 ! Notch signaling pathway GO:0007219 22 21 0,000 0,15792034 0,18304855 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,15792034 0,18293349 ! ear morphogenesis GO:0042471 21 21 0,000 0,15792034 0,18281858 ! organic anion transport GO:0015711 21 21 0,000 0,15792034 0,18270382 ! cholesterol transport GO:0030301 21 21 0,000 0,15792034 0,1825892 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,15792034 0,18247473 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,15792034 0,18236039 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,15792034 0,1822462 ! regulation of proteolysis GO:0030162 21 21 0,000 0,15792034 0,18213216 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,15792034 0,18201825 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,15792034 0,18190449 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,16327846 0,1879589 ! RNA export from nucleus GO:0006405 22 22 0,000 0,16479546 0,18958679 ! regulation of ion transport GO:0043269 22 22 0,000 0,16479546 0,18946852 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,16479546 0,1893504 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,16479546 0,18923242 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,16479546 0,18911459 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,16479546 0,18899691 ! cell chemotaxis GO:0060326 23 22 0,000 0,16479546 0,18887938 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,16479546 0,18876199 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,16479546 0,18864474 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,16479546 0,18852765 ! detection of external stimulus GO:0009581 23 22 0,000 0,16479546 0,18841069 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,16479546 0,18829389 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,16479546 0,18817722 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,16479546 0,1880607 ! aerobic respiration GO:0009060 22 22 0,000 0,16479546 0,18794433 ! cytokine production GO:0001816 22 22 0,000 0,16479546 0,1878281 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,16479546 0,18771201 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,16905122 0,19244064 ! viral infectious cycle GO:0019058 23 23 0,000 0,17161545 0,19523905 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,17161545 0,19511861 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,17161545 0,19499832 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,17161545 0,19487817 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,17161545 0,19475817 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,17161545 0,19463832 ! endocrine system development GO:0035270 23 23 0,000 0,17161545 0,19451862 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,17161545 0,19439906 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,17161545 0,19427965 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,17161545 0,19416039 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,17161545 0,19404127 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,17195107 0,19430154 ! blood vessel development GO:0001568 95 94 1,000 0,17777608 0,20076061 ! cofactor metabolic process GO:0051186 95 94 1,000 0,17777608 0,20063767 ! gliogenesis GO:0042063 24 24 0,000 0,17838073 0,20119687 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,17838073 0,20107381 ! fertilization GO:0009566 25 24 0,000 0,17838073 0,20095091 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,17838073 0,20082815 ! vasculature development GO:0001944 97 96 1,000 0,18363271 0,20661483 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,18509174 0,20812939 ! negative regulation of secretion GO:0051048 26 25 0,000 0,18509174 0,20800248 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,18509174 0,20787573 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,18509174 0,20774913 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,18509174 0,20762269 ! cellular component disassembly GO:0022411 26 25 0,000 0,18509174 0,20749639 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,18509174 0,20737026 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,18509174 0,20724427 ! excretion GO:0007588 25 25 0,000 0,18509174 0,20711844 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,18509174 0,20699276 ! gastrulation GO:0007369 25 25 0,000 0,18509174 0,20686724 ! heart morphogenesis GO:0003007 25 25 0,000 0,18509174 0,20674186 ! regulation of endocytosis GO:0030100 25 25 0,000 0,18509174 0,20661664 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,18509174 0,20649157 ! endocytosis GO:0006897 99 98 1,000 0,18951846 0,21130219 GO:0010324|membrane invagination, ! regulation of system process GO:0044057 98 98 1,000 0,18951846 0,21117444 ! positive regulation of defense response GO:0031349 26 26 0,000 0,1917489 0,21353065 ! glycolysis GO:0006096 26 26 0,000 0,1917489 0,21340171 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,1917489 0,21327292 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,1917489 0,21314429 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,1917489 0,21301581 ! cellular defense response GO:0006968 26 26 0,000 0,1917489 0,21288749 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,1917489 0,21275932 ! regulation of protein secretion GO:0050708 26 26 0,000 0,1917489 0,2126313 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,1917489 0,21250344 GO:0035150|regulation of tube size, ! chloride transport GO:0006821 27 27 0,000 0,19835265 0,21968986 ! peptide metabolic process GO:0006518 29 27 0,000 0,19835265 0,21955791 ! activation of caspase activity GO:0006919 27 27 0,000 0,19835265 0,21942613 ! defense response to bacterium GO:0042742 27 27 0,000 0,19835265 0,2192945 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,19835265 0,21916303 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,19835265 0,21903171 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,20490339 0,22612991 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,20490339 0,22599458 GO:0007254|JNK cascade, ! regulation of muscle contraction GO:0006937 28 28 0,000 0,20490339 0,22585942 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,20490339 0,22572442 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,20490339 0,22558958 ! cartilage development GO:0051216 29 28 0,000 0,20490339 0,22545489 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,21140155 0,23246603 ! viral reproductive process GO:0022415 29 29 0,000 0,21140155 0,23232741 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,21140155 0,23218895 ! leukocyte migration GO:0050900 30 29 0,000 0,21140155 0,23205066 ! antigen processing and presentation GO:0019882 29 29 0,000 0,21140155 0,23191254 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,21140155 0,23177458 ! tRNA processing GO:0008033 29 29 0,000 0,21140155 0,23163678 ! adult behavior GO:0030534 30 29 0,000 0,21140155 0,23149915 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,21140155 0,23136168 ! transition metal ion transport GO:0000041 31 30 0,000 0,21784755 0,2382748 ! RNA catabolic process GO:0006401 30 30 0,000 0,21784755 0,23813347 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,21784755 0,23799231 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,21784755 0,23785132 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,21784755 0,2377105 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,21784755 0,23756984 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,21784755 0,23742935 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,21784755 0,23728903 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,21784755 0,23714887 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,21784755 0,23700887 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,21784755 0,23686905 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,21784755 0,23672938 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,21784755 0,23658988 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,21784755 0,23645055 ! regulation of translational initiation GO:0006446 31 31 0,000 0,22424179 0,24324757 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,22424179 0,24310448 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,22424179 0,24296156 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,22424179 0,24281881 ! ion transmembrane transport GO:0034220 31 31 0,000 0,22424179 0,24267623 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,22424179 0,24253381 ! digestion GO:0007586 31 31 0,000 0,22424179 0,24239156 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,22424179 0,24224948 ! regulation of heart contraction GO:0008016 31 31 0,000 0,22424179 0,24210757 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,22424179 0,24196582 ! camera-type eye development GO:0043010 31 31 0,000 0,22424179 0,24182423 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,22424179 0,24168282 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,22424179 0,24154156 ! cell redox homeostasis GO:0045454 32 32 0,000 0,23058468 0,24822872 ! glucose catabolic process GO:0006007 32 32 0,000 0,23058468 0,24808381 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,23058468 0,24793907 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,23058468 0,2477945 ! nuclear export GO:0051168 32 32 0,000 0,23058468 0,24765009 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,23058468 0,24750586 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,23058468 0,24736179 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,23687663 0,25396371 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,23687663 0,25381606 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,23687663 0,25366858 ! regulation of actin filament length GO:0030832 34 34 0,000 0,24311803 0,26020124 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,24311803 0,26005022 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,24311803 0,25989938 ! viral reproduction GO:0016032 34 34 0,000 0,24311803 0,25974871 ! detection of stimulus GO:0051606 36 34 0,000 0,24311803 0,25959822 ! acute inflammatory response GO:0002526 35 35 0,000 0,2493093 0,26605503 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,2493093 0,26590106 ! regulation of cellular component size GO:0032535 35 35 0,000 0,2493093 0,26574727 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,2493093 0,26559366 ! mesoderm development GO:0007498 35 35 0,000 0,2493093 0,26544023 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,2493093 0,26528697 ! inorganic anion transport GO:0015698 35 35 0,000 0,2493093 0,26513389 ! regulation of immune effector process GO:0002697 35 35 0,000 0,2493093 0,26498099 ! hydrogen transport GO:0006818 36 36 0,000 0,25545081 0,27135207 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,25545081 0,27119576 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,25545081 0,27103964 ! regulation of lipase activity GO:0060191 36 36 0,000 0,25545081 0,27088369 ! activation of immune response GO:0002253 36 36 0,000 0,25545081 0,27072792 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,26154297 0,27702512 ! eye development GO:0001654 37 37 0,000 0,26154297 0,276866 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,26154297 0,27670706 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,26154297 0,27654831 ! adaptive immune response GO:0002250 37 37 0,000 0,26154297 0,27638974 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,26758617 0,28261393 ! neurotransmitter transport GO:0006836 40 38 0,000 0,26758617 0,28245207 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,26758617 0,28229039 ! exocytosis GO:0006887 40 38 0,000 0,26758617 0,2821289 ! hexose catabolic process GO:0019320 38 38 0,000 0,26758617 0,28196759 ! RNA elongation GO:0006354 38 38 0,000 0,26758617 0,28180646 ! response to unfolded protein GO:0006986 39 39 0,000 0,27358079 0,28795511 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,27358079 0,28779075 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,27358079 0,28762658 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,27358079 0,2874626 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,27358079 0,2872988 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,27358079 0,28713519 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,27358079 0,28697177 ! DNA catabolic process GO:0006308 41 40 0,000 0,27952721 0,29304246 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,28542582 0,29905616 ! regulation of caspase activity GO:0043281 41 41 0,000 0,28542582 0,29888624 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,28542582 0,29871651 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,28542582 0,29854698 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,28542582 0,29837764 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,28542582 0,29820849 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,29127699 0,30414929 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,29127699 0,30397706 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,29127699 0,30380503 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,29127699 0,3036332 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! alcohol catabolic process GO:0046164 43 43 0,000 0,2970811 0,30950846 ! mRNA transport GO:0051028 44 44 0,000 0,30283851 0,31532846 ! protein import into nucleus GO:0006606 44 44 0,000 0,30283851 0,31515041 ! vitamin metabolic process GO:0006766 44 44 0,000 0,30283851 0,31497256 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,30283851 0,31479491 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,30854961 0,32055069 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,30854961 0,3203701 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,30854961 0,32018971 ! nuclear import GO:0051170 45 45 0,000 0,30854961 0,32000953 ! protein processing GO:0016485 45 45 0,000 0,30854961 0,31982954 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,31421475 0,32551871 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,31421475 0,32533583 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,31421475 0,32515316 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,31983429 0,3307826 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,3254086 0,33635898 ! protein localization in nucleus GO:0034504 48 48 0,000 0,3254086 0,33617044 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,33093804 0,34169121 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,33642296 0,34715986 ! RNA transport GO:0050658 50 50 0,000 0,33642296 0,34696559 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! transcription initiation GO:0006352 50 50 0,000 0,33642296 0,34677154 ! positive regulation of immune response GO:0050778 51 51 0,000 0,34186371 0,35218268 ! rRNA metabolic process GO:0016072 51 51 0,000 0,34186371 0,35198593 GO:0006364|rRNA processing, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,34186371 0,3517894 ! protein maturation GO:0051604 51 51 0,000 0,34186371 0,35159309 ! RNA localization GO:0006403 52 52 0,000 0,34726064 0,35694443 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,34726064 0,35674546 ! sodium ion transport GO:0006814 53 53 0,000 0,35261409 0,36204333 ! tRNA metabolic process GO:0006399 53 53 0,000 0,35261409 0,36184175 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,35261409 0,36164039 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,35261409 0,36143925 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,35261409 0,36123834 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,36319196 0,37186822 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,36841706 0,37700868 ! ATP metabolic process GO:0046034 57 57 0,000 0,37360003 0,38210037 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,37360003 0,38188844 ! sterol metabolic process GO:0016125 59 59 0,000 0,38384098 0,3921391 ! protein localization in organelle GO:0033365 59 59 0,000 0,38384098 0,39192184 ! potassium ion transport GO:0006813 60 60 0,000 0,38889961 0,3968671 ! protein polymerization GO:0051258 65 60 0,000 0,38889961 0,39664747 ! cellular respiration GO:0045333 62 61 0,000 0,39391744 0,40154306 ! protein import GO:0017038 62 62 0,000 0,3988948 0,406392 ! glucose metabolic process GO:0006006 63 63 0,000 0,40383201 0,4111947 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,40872939 0,41595155 ! angiogenesis GO:0001525 65 64 0,000 0,40872939 0,415722 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,40872939 0,4154927 ! anion transport GO:0006820 65 65 0,000 0,41358725 0,42019917 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,4184059 0,42486064 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,42318566 0,42947751 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,42318566 0,42924115 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,42792683 0,43381141 ! regulation of translation GO:0006417 69 69 0,000 0,43262972 0,43833786 ! translational elongation GO:0006414 71 71 0,000 0,44192187 0,4475066 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,44192187 0,44726085 ! ribosome biogenesis GO:0042254 71 71 0,000 0,44192187 0,44701537 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,44192187 0,44677017 ! secretion by cell GO:0032940 75 72 0,000 0,44651174 0,4511629 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,44651174 0,45091569 ! regulation of cytokine production GO:0001817 72 72 0,000 0,44651174 0,45066875 ! electron transport chain GO:0022900 75 74 0,000 0,45558051 0,45957027 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,46006002 0,46383513 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,46450331 0,46805883 ! microtubule-based movement GO:0007018 82 78 0,000 0,47328244 0,47664456 ! regulation of immune response GO:0050776 78 78 0,000 0,47328244 0,47638424 ! nuclear transport GO:0051169 79 79 0,000 0,47761884 0,48048664 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,48192017 0,4845493 ! ncRNA processing GO:0034470 83 83 0,000 0,49461652 0,49704376 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,50291046 0,50510299 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,50700715 0,50894019 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,50700715 0,50866314 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,51510131 0,51650256 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,5230649 0,52420262 ! DNA replication GO:0006260 91 91 0,000 0,52699839 0,52785762 ! visual perception GO:0007601 93 92 0,000 0,5309 0,53147676 GO:0050953|sensory perception of light stimulus, ! positive regulation of immune system process GO:0002684 92 92 0,000 0,5309 0,53118822 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,55365458 0,55365458