pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6610-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of phosphorus metabolic process GO:0010563 45 25 6,000 8,137E-10 1,872E-06 GO:0045936|negative regulation of phosphate metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 33 21 5,000 1,215E-08 1,397E-05 ! negative regulation of phosphorylation GO:0042326 41 23 5,000 2,231E-08 1,71E-05 ! interphase of mitotic cell cycle GO:0051329 156 86 8,000 3,034E-08 1,745E-05 ! interphase GO:0051325 159 88 8,000 3,719E-08 1,711E-05 ! regulation of lipid kinase activity GO:0043550 12 7 3,000 1,393E-07 5,339E-05 ! S phase GO:0051320 8 8 3,000 2,768E-07 9,096E-05 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 99 57 6,000 3,61E-07 1,038E-04 ! negative regulation of kinase activity GO:0033673 100 58 6,000 4,078E-07 1,042E-04 ! negative regulation of transferase activity GO:0051348 105 61 6,000 5,799E-07 1,334E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 4,000 1,194E-06 2,497E-04 ! serine family amino acid biosynthetic process GO:0009070 13 11 3,000 1,281E-06 2,455E-04 ! negative regulation of protein modification process GO:0031400 50 26 4,000 1,824E-06 3,228E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 3,000 2,74E-06 4,502E-04 ! glycine metabolic process GO:0006544 22 14 3,000 3,812E-06 5,845E-04 ! nuclear migration GO:0007097 10 5 2,000 5,076E-06 7,296E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 2,000 5,076E-06 6,867E-04 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 5,076E-06 6,486E-04 GO:0031272|regulation of pseudopodium assembly, ! mitotic sister chromatid segregation GO:0000070 45 32 4,000 5,372E-06 6,503E-04 ! sister chromatid segregation GO:0000819 46 33 4,000 6,29E-06 7,234E-04 ! cell-substrate junction assembly GO:0007044 39 17 3,000 8,895E-06 9,742E-04 ! positive regulation of protein ubiquitination GO:0031398 8 6 2,000 1,009E-05 1,055E-03 ! macrophage differentiation GO:0030225 10 6 2,000 1,009E-05 1,009E-03 ! peptidyl-amino acid modification GO:0018193 147 93 6,000 1,016E-05 9,738E-04 ! apoptotic mitochondrial changes GO:0008637 29 18 3,000 1,136E-05 1,046E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 5,000 1,152E-05 1,019E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 5,000 1,263E-05 1,076E-03 ! pigmentation GO:0043473 74 38 4,000 1,288E-05 1,058E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 1,667E-05 1,322E-03 ! fibrinolysis GO:0042730 9 7 2,000 1,756E-05 1,346E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,756E-05 1,303E-03 ! establishment of nucleus localization GO:0040023 13 7 2,000 1,756E-05 1,262E-03 ! positive regulation of phosphorylation GO:0042327 102 70 5,000 2,123E-05 1,479E-03 ! myeloid leukocyte differentiation GO:0002573 33 21 3,000 2,181E-05 1,476E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 2,391E-05 1,571E-03 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 5,000 2,496E-05 1,595E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 2,792E-05 1,736E-03 ! induction of positive chemotaxis GO:0050930 14 8 2,000 2,792E-05 1,69E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 2,792E-05 1,647E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 2,792E-05 1,606E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,792E-05 1,566E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 3,000 3,187E-05 1,745E-03 ! positive regulation of protein modification process GO:0031401 107 78 5,000 3,944E-05 2,11E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 4,164E-05 2,176E-03 ! nucleus localization GO:0051647 15 9 2,000 4,164E-05 2,128E-03 ! peptidyl-tyrosine modification GO:0018212 37 25 3,000 4,496E-05 2,248E-03 ! ear development GO:0043583 72 50 4,000 5,03E-05 2,462E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 5,913E-05 2,833E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 5,913E-05 2,775E-03 ! serine family amino acid metabolic process GO:0009069 37 27 3,000 6,161E-05 2,834E-03 ! cell junction assembly GO:0034329 56 28 3,000 7,142E-05 3,221E-03 ! filopodium assembly GO:0046847 19 11 2,000 8,082E-05 3,575E-03 ! regulation of positive chemotaxis GO:0050926 17 11 2,000 8,082E-05 3,507E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 24 11 2,000 8,082E-05 3,442E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 8,082E-05 3,38E-03 ! nitric oxide metabolic process GO:0046209 14 11 2,000 8,082E-05 3,32E-03 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of glucose import GO:0046325 14 11 2,000 8,082E-05 3,261E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 8,082E-05 3,205E-03 GO:0042130|negative regulation of T cell proliferation, ! chromosome segregation GO:0007059 83 57 4,000 9,501E-05 3,704E-03 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 9,501E-05 3,642E-03 ! regulation of skeletal muscle fiber development GO:0048742 20 12 2,000 1,071E-04 4,039E-03 ! microspike assembly GO:0030035 23 12 2,000 1,071E-04 3,974E-03 ! lung development GO:0030324 94 59 4,000 1,121E-04 4,094E-03 ! myeloid cell differentiation GO:0030099 85 59 4,000 1,121E-04 4,03E-03 ! regulation of protein stability GO:0031647 48 32 3,000 1,223E-04 4,329E-03 ! cell junction organization GO:0034330 63 33 3,000 1,384E-04 4,821E-03 ! negative regulation of cell growth GO:0030308 106 62 4,000 1,422E-04 4,881E-03 ! respiratory tube development GO:0030323 99 62 4,000 1,422E-04 4,809E-03 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 5,000 1,498E-04 4,994E-03 ! cellular response to insulin stimulus GO:0032869 52 34 3,000 1,558E-04 5,12E-03 ! negative regulation of cell size GO:0045792 108 64 4,000 1,654E-04 5,357E-03 ! respiratory system development GO:0060541 100 64 4,000 1,654E-04 5,283E-03 ! regulation of skeletal muscle tissue development GO:0048641 22 14 2,000 1,752E-04 5,519E-03 ! negative regulation of blood coagulation GO:0030195 19 14 2,000 1,752E-04 5,444E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,752E-04 5,372E-03 ! regulation of protein ubiquitination GO:0031396 19 15 2,000 2,177E-04 6,587E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 2,177E-04 6,502E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 2,177E-04 6,418E-03 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 2,000 2,177E-04 6,337E-03 ! dopamine metabolic process GO:0042417 30 15 2,000 2,177E-04 6,258E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 2,177E-04 6,181E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! response to drug GO:0042493 108 69 4,000 2,36E-04 6,62E-03 ! G1 phase GO:0051318 27 16 2,000 2,663E-04 7,38E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 2,663E-04 7,292E-03 ! inner ear receptor cell differentiation GO:0060113 30 16 2,000 2,663E-04 7,206E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 2,679E-04 7,164E-03 ! cell growth GO:0016049 61 39 3,000 2,679E-04 7,081E-03 ! JAK-STAT cascade GO:0007259 53 40 3,000 2,958E-04 7,73E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 3,215E-04 8,308E-03 ! memory GO:0007613 25 17 2,000 3,215E-04 8,215E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 3,215E-04 8,125E-03 ! negative regulation of protein catabolic process GO:0042177 26 17 2,000 3,215E-04 8,037E-03 ! peptidyl-serine modification GO:0018209 27 17 2,000 3,215E-04 7,95E-03 ! negative regulation of coagulation GO:0050819 23 17 2,000 3,215E-04 7,866E-03 ! epithelial cell differentiation GO:0030855 55 41 3,000 3,257E-04 7,886E-03 ! cellular response to hormone stimulus GO:0032870 109 74 4,000 3,276E-04 7,848E-03 ! negative regulation of growth GO:0045926 123 75 4,000 3,487E-04 8,269E-03 ! amine biosynthetic process GO:0009309 97 76 4,000 3,709E-04 8,705E-03 ! mechanoreceptor differentiation GO:0042490 32 18 2,000 3,835E-04 8,909E-03 ! estrogen receptor signaling pathway GO:0030520 30 18 2,000 3,835E-04 8,82E-03 ! regulation of glucose import GO:0046324 21 18 2,000 3,835E-04 8,733E-03 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 2,000 3,835E-04 8,647E-03 ! negative regulation of T cell activation GO:0050868 25 18 2,000 3,835E-04 8,563E-03 ! response to insulin stimulus GO:0032868 63 43 3,000 3,92E-04 8,669E-03 ! one-carbon metabolic process GO:0006730 110 77 4,000 3,941E-04 8,633E-03 ! cellular amino acid biosynthetic process GO:0008652 51 44 3,000 4,285E-04 9,298E-03 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 4,285E-04 9,211E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 4,527E-04 9,641E-03 ! response to alkaloid GO:0043279 32 19 2,000 4,527E-04 9,553E-03 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 2,000 4,527E-04 9,466E-03 ! cell structure disassembly during apoptosis GO:0006921 24 19 2,000 4,527E-04 9,381E-03 ! apoptotic nuclear changes GO:0030262 24 19 2,000 4,527E-04 9,297E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 4,527E-04 9,215E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 4,674E-04 9,43E-03 ! forebrain development GO:0030900 131 80 4,000 4,703E-04 9,407E-03 ! regulation of cell cycle process GO:0010564 122 81 4,000 4,981E-04 9,876E-03 ! response to ethanol GO:0045471 37 20 2,000 5,295E-04 0,01040847 ! multicellular organismal response to stress GO:0033555 32 20 2,000 5,295E-04 0,01032027 ! positive regulation of locomotion GO:0040017 35 20 2,000 5,295E-04 0,01023354 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 2,000 5,295E-04 0,01014826 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 5,526E-04 0,01050394 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 3,000 5,991E-04 0,01129434 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 2,000 6,141E-04 0,01148288 ! regulation of chemotaxis GO:0050920 36 21 2,000 6,141E-04 0,01139028 ! dendrite development GO:0016358 35 21 2,000 6,141E-04 0,01129916 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 6,141E-04 0,01120948 ! response to cytokine stimulus GO:0034097 47 21 2,000 6,141E-04 0,01112122 ! sleep GO:0030431 11 5 1,000 6,357E-04 0,01142317 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 6,357E-04 0,01133462 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 6,357E-04 0,01124743 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 6,357E-04 0,01116157 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 6,357E-04 0,01107701 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 6,357E-04 0,01099373 ! epithelial cell proliferation GO:0050673 6 5 1,000 6,357E-04 0,01091168 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 6,357E-04 0,01083086 ! valine metabolic process GO:0006573 8 5 1,000 6,357E-04 0,01075122 ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 6,357E-04 0,01067274 ! early endosome to late endosome transport GO:0045022 11 5 1,000 6,357E-04 0,0105954 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 1,000 6,357E-04 0,01051918 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 6,357E-04 0,01044404 ! monocyte differentiation GO:0030224 8 5 1,000 6,357E-04 0,01036997 ! neural tube patterning GO:0021532 6 5 1,000 6,357E-04 0,01029694 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 1,000 6,357E-04 0,01022493 ! regulation of mitochondrial depolarization GO:0051900 9 5 1,000 6,357E-04 0,01015393 ! regulation of sensory perception GO:0051931 6 5 1,000 6,357E-04 0,0100839 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 6,357E-04 0,01001483 ! receptor biosynthetic process GO:0032800 6 5 1,000 6,357E-04 9,947E-03 ! cell cycle arrest GO:0007050 150 86 4,000 6,556E-04 0,01018828 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 7,069E-04 0,01091129 ! glutamate signaling pathway GO:0007215 34 22 2,000 7,069E-04 0,01083855 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 7,069E-04 0,01076677 GO:0010810|regulation of cell-substrate adhesion, ! regulation of behavior GO:0050795 38 22 2,000 7,069E-04 0,01069594 ! regulation of blood coagulation GO:0030193 34 22 2,000 7,069E-04 0,01062603 ! leukocyte differentiation GO:0002521 143 90 4,000 8,063E-04 0,01204271 ! negative regulation of catabolic process GO:0009895 34 23 2,000 8,081E-04 0,01199132 ! establishment of organelle localization GO:0051656 85 52 3,000 8,13E-04 0,011987 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 9,181E-04 0,01345024 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 9,181E-04 0,01336512 ! receptor metabolic process GO:0043112 37 24 2,000 9,181E-04 0,01328106 ! regulation of mitosis GO:0007088 84 54 3,000 9,38E-04 0,01348387 GO:0051783|regulation of nuclear division, ! prostate gland development GO:0030850 9 6 1,000 9,485E-04 0,01355058 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 9,485E-04 0,01346693 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 9,485E-04 0,01338431 ! response to interferon-gamma GO:0034341 12 6 1,000 9,485E-04 0,0133027 ! pigment granule organization GO:0048753 11 6 1,000 9,485E-04 0,01322208 ! ER overload response GO:0006983 7 6 1,000 9,485E-04 0,01314243 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 1,000 9,485E-04 0,01306373 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 9,485E-04 0,01298597 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 1,000 9,485E-04 0,01290913 ! wound healing, spreading of epidermal cells GO:0035313 10 6 1,000 9,485E-04 0,0128332 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 9,485E-04 0,01275815 ! regulation of myeloid cell apoptosis GO:0033032 10 6 1,000 9,485E-04 0,01268397 ! protein deubiquitination GO:0016579 8 6 1,000 9,485E-04 0,01261065 GO:0070646|protein modification by small protein removal, ! midbrain development GO:0030901 6 6 1,000 9,485E-04 0,01253818 ! negative regulation of B cell activation GO:0050869 9 6 1,000 9,485E-04 0,01246653 ! regulation of binding GO:0051098 151 95 4,000 1,029E-03 0,01345306 ! regulation of chromosome organization GO:0033044 35 25 2,000 1,037E-03 0,01347764 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 1,037E-03 0,01340193 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 1,076E-03 0,01382476 ! regulation of response to external stimulus GO:0032101 139 96 4,000 1,079E-03 0,01378809 ! regulation of coagulation GO:0050818 39 26 2,000 1,166E-03 0,01481137 ! steroid hormone receptor signaling pathway GO:0030518 96 58 3,000 1,227E-03 0,01551221 ! catechol metabolic process GO:0009712 43 27 2,000 1,304E-03 0,0163839 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 1,304E-03 0,01629486 ! negative regulation of transcription regulator activity GO:0090048 47 27 2,000 1,304E-03 0,01620678 GO:0043433|negative regulation of transcription factor activity, ! actin filament organization GO:0007015 95 59 3,000 1,309E-03 0,01618166 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 1,321E-03 0,01624679 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 1,321E-03 0,01616037 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 1,321E-03 0,01607486 ! lipoprotein transport GO:0042953 9 7 1,000 1,321E-03 0,01599026 ! microtubule bundle formation GO:0001578 8 7 1,000 1,321E-03 0,01590654 ! regulation of pigmentation during development GO:0048070 15 7 1,000 1,321E-03 0,01582369 ! organ growth GO:0035265 11 7 1,000 1,321E-03 0,01574171 ! behavioral fear response GO:0001662 13 7 1,000 1,321E-03 0,01566056 GO:0002209|behavioral defense response, ! response to UV-B GO:0010224 11 7 1,000 1,321E-03 0,01558025 ! B cell lineage commitment GO:0002326 17 7 1,000 1,321E-03 0,01550076 ! regulation of fat cell differentiation GO:0045598 9 7 1,000 1,321E-03 0,01542208 ! positive regulation of monooxygenase activity GO:0032770 11 7 1,000 1,321E-03 0,01534419 ! T cell lineage commitment GO:0002360 12 7 1,000 1,321E-03 0,01526708 ! peptidyl-threonine modification GO:0018210 18 7 1,000 1,321E-03 0,01519075 ! regulation of synaptogenesis GO:0051963 10 7 1,000 1,321E-03 0,01511517 ! dopamine biosynthetic process GO:0042416 15 7 1,000 1,321E-03 0,01504034 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 1,321E-03 0,01496625 ! trophectodermal cell differentiation GO:0001829 8 7 1,000 1,321E-03 0,01489289 ! phenol metabolic process GO:0018958 44 28 2,000 1,451E-03 0,01628454 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 1,451E-03 0,01620549 ! positive regulation of multicellular organism growth GO:0040018 38 28 2,000 1,451E-03 0,0161272 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,451E-03 0,01604967 ! placenta development GO:0001890 37 28 2,000 1,451E-03 0,01597288 ! regulation of B cell activation GO:0050864 42 28 2,000 1,451E-03 0,01589682 ! organelle localization GO:0051640 96 62 3,000 1,574E-03 0,01716106 ! regulation of transcription factor activity GO:0051090 97 63 3,000 1,671E-03 0,01812522 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 3,000 1,671E-03 0,01804013 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,752E-03 0,01882924 ! succinate metabolic process GO:0006105 14 8 1,000 1,752E-03 0,01874166 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,752E-03 0,0186549 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,752E-03 0,01856893 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,752E-03 0,01848375 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 1,000 1,752E-03 0,01839935 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! L-phenylalanine metabolic process GO:0006558 8 8 1,000 1,752E-03 0,01831572 GO:0006559|L-phenylalanine catabolic process, ! melanin metabolic process GO:0006582 12 8 1,000 1,752E-03 0,01823284 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,752E-03 0,01815071 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 1,752E-03 0,01806932 ! induction of an organ GO:0001759 11 8 1,000 1,752E-03 0,01798865 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,752E-03 0,0179087 ! neuromuscular process controlling posture GO:0050884 11 8 1,000 1,752E-03 0,01782946 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,752E-03 0,01775092 ! cell cycle checkpoint GO:0000075 108 64 3,000 1,771E-03 0,01786562 ! hindbrain development GO:0030902 45 30 2,000 1,778E-03 0,01785521 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,778E-03 0,01777758 ! regulation of striated muscle tissue development GO:0016202 47 31 2,000 1,957E-03 0,0194822 ! leukocyte chemotaxis GO:0030595 43 31 2,000 1,957E-03 0,01939822 GO:0060326|cell chemotaxis, ! regulation of muscle development GO:0048634 48 32 2,000 2,146E-03 0,02118814 ! regulation of synaptic plasticity GO:0048167 52 32 2,000 2,146E-03 0,02109759 ! learning or memory GO:0007611 123 68 3,000 2,214E-03 0,02167255 ! regulation of developmental growth GO:0048638 13 9 1,000 2,241E-03 0,02183631 ! GTP metabolic process GO:0046039 9 9 1,000 2,241E-03 0,02174418 ! response to pain GO:0048265 16 9 1,000 2,241E-03 0,02165282 ! T cell selection GO:0045058 18 9 1,000 2,241E-03 0,02156222 ! phosphagen metabolic process GO:0006599 12 9 1,000 2,241E-03 0,02147238 GO:0006600|creatine metabolic process, ! indolalkylamine metabolic process GO:0006586 14 9 1,000 2,241E-03 0,02138328 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! receptor clustering GO:0043113 15 9 1,000 2,241E-03 0,02129492 ! epithelial cell development GO:0002064 10 9 1,000 2,241E-03 0,02120728 ! motor axon guidance GO:0008045 14 9 1,000 2,241E-03 0,02112037 ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 2,241E-03 0,02103416 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 1,000 2,241E-03 0,02094866 ! response to amine stimulus GO:0014075 13 9 1,000 2,241E-03 0,02086385 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! oocyte differentiation GO:0009994 12 9 1,000 2,241E-03 0,02077972 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 1,000 2,241E-03 0,02069627 ! spleen development GO:0048536 15 9 1,000 2,241E-03 0,02061348 ! blastocyst formation GO:0001825 12 9 1,000 2,241E-03 0,02053135 ! embryonic placenta development GO:0001892 12 9 1,000 2,241E-03 0,02044988 ! response to nicotine GO:0035094 16 9 1,000 2,241E-03 0,02036905 ! regulation of synapse organization GO:0050807 12 9 1,000 2,241E-03 0,02028886 ! carbohydrate homeostasis GO:0033500 39 33 2,000 2,347E-03 0,02117137 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 2,000 2,347E-03 0,02108867 ! negative regulation of DNA binding GO:0043392 54 33 2,000 2,347E-03 0,02100661 ! cytokinesis GO:0000910 52 33 2,000 2,347E-03 0,02092519 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 2,559E-03 0,02272769 ! development of primary male sexual characteristics GO:0046546 44 34 2,000 2,559E-03 0,02264027 ! neuron migration GO:0001764 46 34 2,000 2,559E-03 0,02255353 ! response to hypoxia GO:0001666 132 72 3,000 2,729E-03 0,02395578 ! regulation of synaptic transmission GO:0050804 109 72 3,000 2,729E-03 0,02386469 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 2,783E-03 0,02424481 ! folic acid and derivative biosynthetic process GO:0009396 10 10 1,000 2,786E-03 0,02418005 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 2,786E-03 0,02408915 ! hair follicle morphogenesis GO:0031069 17 10 1,000 2,786E-03 0,02399892 ! hippocampus development GO:0021766 19 10 1,000 2,786E-03 0,02390938 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 2,786E-03 0,02382049 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 2,786E-03 0,02373227 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 2,786E-03 0,0236447 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 2,786E-03 0,02355777 ! B cell proliferation GO:0042100 14 10 1,000 2,786E-03 0,02347148 ! fear response GO:0042596 16 10 1,000 2,786E-03 0,02338581 ! negative regulation of ossification GO:0030279 19 10 1,000 2,786E-03 0,02330077 ! alpha-beta T cell activation GO:0046631 16 10 1,000 2,786E-03 0,02321635 ! purine ribonucleotide catabolic process GO:0009154 14 10 1,000 2,786E-03 0,02313254 ! DNA methylation GO:0006306 15 10 1,000 2,786E-03 0,02304933 GO:0006305|DNA alkylation, ! developmental induction GO:0031128 13 10 1,000 2,786E-03 0,02296671 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 2,786E-03 0,02288469 ! regulation of synapse structure and activity GO:0050803 13 10 1,000 2,786E-03 0,02280325 ! negative regulation of transport GO:0051051 116 73 3,000 2,869E-03 0,02340169 ! mitochondrion organization GO:0007005 104 73 3,000 2,869E-03 0,02331899 ! response to oxygen levels GO:0070482 137 74 3,000 3,014E-03 0,02441311 ! response to reactive oxygen species GO:0000302 55 36 2,000 3,018E-03 0,02435662 ! negative regulation of binding GO:0051100 58 36 2,000 3,018E-03 0,02427146 ! learning GO:0007612 67 37 2,000 3,265E-03 0,02616702 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 3,387E-03 0,02704979 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 3,387E-03 0,02695619 GO:0000725|recombinational repair, ! detection of mechanical stimulus GO:0050982 15 11 1,000 3,387E-03 0,02686324 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 3,387E-03 0,02677092 ! ribonucleotide catabolic process GO:0009261 16 11 1,000 3,387E-03 0,02667924 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 3,387E-03 0,02658819 ! nucleoside triphosphate catabolic process GO:0009143 15 11 1,000 3,387E-03 0,02649775 ! T cell homeostasis GO:0043029 20 11 1,000 3,387E-03 0,02640793 ! aromatic amino acid family catabolic process GO:0009074 13 11 1,000 3,387E-03 0,02631871 ! male genitalia development GO:0030539 13 11 1,000 3,387E-03 0,0262301 ! digestive tract morphogenesis GO:0048546 15 11 1,000 3,387E-03 0,02614208 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of DNA binding GO:0051101 119 77 3,000 3,48E-03 0,02677076 ! gland development GO:0048732 148 77 3,000 3,48E-03 0,02668153 ! regulation of transmission of nerve impulse GO:0051969 116 77 3,000 3,48E-03 0,02659288 ! regulation of T cell proliferation GO:0042129 58 38 2,000 3,524E-03 0,02684092 ! multicellular organismal metabolic process GO:0044236 50 39 2,000 3,796E-03 0,02881226 ! male sex differentiation GO:0046661 53 39 2,000 3,796E-03 0,02871748 ! histone acetylation GO:0016573 23 12 1,000 4,043E-03 0,03048894 ! gland morphogenesis GO:0022612 23 12 1,000 4,043E-03 0,03038931 ! peptidyl-lysine modification GO:0018205 18 12 1,000 4,043E-03 0,03029032 ! response to gamma radiation GO:0010332 20 12 1,000 4,043E-03 0,03019197 ! positive regulation of response to external stimulus GO:0032103 65 40 2,000 4,079E-03 0,03036506 ! inner ear development GO:0048839 57 40 2,000 4,079E-03 0,03026711 ! positive regulation of protein transport GO:0051222 55 40 2,000 4,079E-03 0,03016979 ! regulation of neurological system process GO:0031644 122 81 3,000 4,174E-03 0,03077072 ! regulation of T cell differentiation GO:0045580 59 41 2,000 4,376E-03 0,03215466 ! regulation of cell adhesion GO:0030155 159 83 3,000 4,554E-03 0,03335549 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 4,685E-03 0,0342073 ! cellular component disassembly GO:0022411 64 42 2,000 4,685E-03 0,03409905 ! branching morphogenesis of a tube GO:0048754 72 42 2,000 4,685E-03 0,03399148 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 4,753E-03 0,0343773 ! pteridine and derivative biosynthetic process GO:0042559 15 13 1,000 4,753E-03 0,03426954 ! exocrine system development GO:0035272 27 13 1,000 4,753E-03 0,03416245 ! negative regulation of mitotic cell cycle GO:0045930 23 13 1,000 4,753E-03 0,03405602 ! regulation of exocytosis GO:0017157 17 13 1,000 4,753E-03 0,03395026 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 4,753E-03 0,03384515 ! genitalia development GO:0048806 15 13 1,000 4,753E-03 0,03374069 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 4,753E-03 0,03363687 ! cellular pigmentation GO:0033059 24 13 1,000 4,753E-03 0,03353369 ! lymphocyte homeostasis GO:0002260 24 13 1,000 4,753E-03 0,03343114 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 4,956E-03 0,03475231 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 4,956E-03 0,03464668 ! regulation of protein localization GO:0032880 132 85 3,000 4,956E-03 0,03454169 ! regulation of membrane potential GO:0042391 128 85 3,000 4,956E-03 0,03443733 ! negative regulation of multicellular organismal process GO:0051241 133 85 3,000 4,956E-03 0,03433361 ! leukocyte migration GO:0050900 60 43 2,000 5,007E-03 0,03458207 ! neuromuscular process GO:0050905 79 43 2,000 5,007E-03 0,03447853 ! activation of caspase activity GO:0006919 65 43 2,000 5,007E-03 0,03437561 ! regulation of cell projection organization GO:0031344 83 44 2,000 5,342E-03 0,03656647 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 5,342E-03 0,03645797 ! regulation of inflammatory response GO:0050727 60 44 2,000 5,342E-03 0,03635011 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 5,516E-03 0,03742429 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 5,516E-03 0,03731422 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 5,516E-03 0,03720479 ! heterophilic cell adhesion GO:0007157 29 14 1,000 5,516E-03 0,03709601 ! limbic system development GO:0021761 25 14 1,000 5,516E-03 0,03698785 ! startle response GO:0001964 21 14 1,000 5,516E-03 0,03688033 ! epidermis morphogenesis GO:0048730 29 14 1,000 5,516E-03 0,03677343 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 5,516E-03 0,03666715 GO:0031114|regulation of microtubule depolymerization, ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 5,516E-03 0,03656148 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 27 14 1,000 5,516E-03 0,03645642 ! catecholamine biosynthetic process GO:0042423 23 14 1,000 5,516E-03 0,03635196 ! positive regulation of defense response GO:0031349 59 45 2,000 5,69E-03 0,03739184 ! cell maturation GO:0048469 60 45 2,000 5,69E-03 0,03728531 ! reproductive developmental process GO:0003006 127 89 3,000 5,831E-03 0,03809762 ! response to UV GO:0009411 75 46 2,000 6,052E-03 0,03942937 ! metencephalon development GO:0022037 19 15 1,000 6,331E-03 0,04113456 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 6,331E-03 0,04101869 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 6,331E-03 0,04090347 ! lipid phosphorylation GO:0046834 23 15 1,000 6,331E-03 0,0407889 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 1,000 6,331E-03 0,04067496 ! regulation of survival gene product expression GO:0045884 20 15 1,000 6,331E-03 0,04056166 ! cerebral cortex development GO:0021987 29 15 1,000 6,331E-03 0,04044899 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 6,331E-03 0,04033694 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 6,331E-03 0,04022551 ! folic acid and derivative metabolic process GO:0006760 17 15 1,000 6,331E-03 0,0401147 ! defense response to virus GO:0051607 27 15 1,000 6,331E-03 0,04000449 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 6,331E-03 0,03989489 ! negative regulation of immune system process GO:0002683 73 47 2,000 6,426E-03 0,04038498 ! cell fate commitment GO:0045165 141 92 3,000 6,55E-03 0,04105018 ! positive regulation of caspase activity GO:0043280 72 48 2,000 6,815E-03 0,04259358 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 2,000 6,815E-03 0,04247815 ! regulation of DNA replication GO:0006275 75 48 2,000 6,815E-03 0,04236334 ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 6,815E-03 0,04224916 ! protein amino acid acetylation GO:0006473 28 16 1,000 7,198E-03 0,04450099 ! regulation of protein binding GO:0043393 27 16 1,000 7,198E-03 0,04438168 ! regulation of dephosphorylation GO:0035303 33 16 1,000 7,198E-03 0,04426301 ! oogenesis GO:0048477 23 16 1,000 7,198E-03 0,04414498 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 7,198E-03 0,04402757 ! aromatic compound biosynthetic process GO:0019438 18 16 1,000 7,198E-03 0,04391079 ! regulation of angiogenesis GO:0045765 94 49 2,000 7,217E-03 0,04391386 ! regulation of intracellular transport GO:0032386 78 49 2,000 7,217E-03 0,04379799 ! morphogenesis of a branching structure GO:0001763 86 49 2,000 7,217E-03 0,04368273 ! cartilage development GO:0051216 70 49 2,000 7,217E-03 0,04356808 ! regulation of cellular component biogenesis GO:0044087 158 96 3,000 7,598E-03 0,04574712 ! response to light stimulus GO:0009416 153 96 3,000 7,598E-03 0,04562768 ! lipid modification GO:0030258 73 50 2,000 7,633E-03 0,04571919 ! positive regulation of growth GO:0045927 67 50 2,000 7,633E-03 0,04560044 ! regulation of multicellular organism growth GO:0040014 65 50 2,000 7,633E-03 0,0454823 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 8,063E-03 0,04791957 ! positive regulation of cell migration GO:0030335 92 51 2,000 8,063E-03 0,04779606 ! regulation of protein catabolic process GO:0042176 77 51 2,000 8,063E-03 0,04767319 ! glycerol metabolic process GO:0006071 20 17 1,000 8,114E-03 0,04785392 ! signal complex assembly GO:0007172 29 17 1,000 8,114E-03 0,04773154 ! forelimb morphogenesis GO:0035136 19 17 1,000 8,114E-03 0,04760977 ! regulation of viral genome replication GO:0045069 24 17 1,000 8,114E-03 0,04748863 ! actin filament bundle formation GO:0051017 26 17 1,000 8,114E-03 0,0473681 ! neuromuscular junction development GO:0007528 23 17 1,000 8,114E-03 0,04724818 ! long-chain fatty acid transport GO:0015909 24 17 1,000 8,114E-03 0,04712886 ! proximal/distal pattern formation GO:0009954 25 17 1,000 8,114E-03 0,04701015 ! aromatic compound catabolic process GO:0019439 22 17 1,000 8,114E-03 0,04689204 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 8,114E-03 0,04677451 ! positive regulation of synaptic transmission GO:0050806 24 17 1,000 8,114E-03 0,04665758 ! aging GO:0007568 79 52 2,000 8,507E-03 0,04879248 ! cell projection assembly GO:0030031 76 53 2,000 8,965E-03 0,05129136 ! positive regulation of DNA replication GO:0045740 29 18 1,000 9,081E-03 0,05182544 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 9,081E-03 0,05169716 ! pigmentation during development GO:0048066 31 18 1,000 9,081E-03 0,05156952 ! prostaglandin metabolic process GO:0006693 31 18 1,000 9,081E-03 0,0514425 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 35 18 1,000 9,081E-03 0,0513161 ! somitogenesis GO:0001756 24 18 1,000 9,081E-03 0,05119033 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 1,000 9,081E-03 0,05106517 ! purine nucleotide catabolic process GO:0006195 26 18 1,000 9,081E-03 0,05094062 ! gut development GO:0048565 26 18 1,000 9,081E-03 0,05081668 ! regulation of protein complex assembly GO:0043254 81 54 2,000 9,437E-03 0,05268231 ! DNA catabolic process GO:0006308 67 54 2,000 9,437E-03 0,05255475 ! pteridine and derivative metabolic process GO:0042558 23 19 1,000 0,01009578 0,05608766 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 0,01009578 0,05595251 ! regulation of postsynaptic membrane potential GO:0060078 30 19 1,000 0,01009578 0,055818 ! regeneration GO:0031099 32 19 1,000 0,01009578 0,05568415 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 0,01009578 0,05555093 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 0,01009578 0,05541835 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 0,01009578 0,0552864 ! response to lipopolysaccharide GO:0032496 26 19 1,000 0,01009578 0,05515508 ! renal system process GO:0003014 35 19 1,000 0,01009578 0,05502438 ! positive regulation of neurological system process GO:0031646 28 19 1,000 0,01009578 0,0548943 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 0,01009578 0,05476483 ! aromatic amino acid family metabolic process GO:0009072 24 19 1,000 0,01009578 0,05463598 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 0,01009578 0,05450772 ! protein stabilization GO:0050821 26 19 1,000 0,01009578 0,05438007 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 0,01042425 0,05601817 ! positive regulation of cell motion GO:0051272 99 56 2,000 0,01042425 0,0558876 ! multicellular organism reproduction GO:0032504 83 57 2,000 0,01093949 0,05851355 GO:0048609|reproductive process in a multicellular organism, ! developmental maturation GO:0021700 75 57 2,000 0,01093949 0,05837779 ! neurotransmitter metabolic process GO:0042133 30 20 1,000 0,0111587 0,05940975 ! fatty acid beta-oxidation GO:0006635 31 20 1,000 0,0111587 0,05927254 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 0,0111587 0,05913597 ! pallium development GO:0021543 38 20 1,000 0,0111587 0,05900003 ! DNA modification GO:0006304 28 20 1,000 0,0111587 0,05886471 ! positive regulation of B cell activation GO:0050871 31 20 1,000 0,0111587 0,05873 ! collagen catabolic process GO:0030574 25 20 1,000 0,0111587 0,05859592 ! alditol metabolic process GO:0019400 24 20 1,000 0,0111587 0,05846244 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 0,01226866 0,06413163 ! gluconeogenesis GO:0006094 25 21 1,000 0,01226866 0,06398621 ! protein amino acid acylation GO:0043543 37 21 1,000 0,01226866 0,06384145 ! visual behavior GO:0007632 39 21 1,000 0,01226866 0,06369733 ! ovarian follicle development GO:0001541 30 21 1,000 0,01226866 0,06355387 ! cell aging GO:0007569 32 21 1,000 0,01226866 0,06341105 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 0,01226866 0,06326888 ! fatty acid transport GO:0015908 30 21 1,000 0,01226866 0,06312733 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 0,01226866 0,06298643 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 0,01226866 0,06284614 ! regulation of homeostatic process GO:0032844 105 60 2,000 0,01257251 0,0642595 ! regulation of heart contraction GO:0008016 91 60 2,000 0,01257251 0,06411702 ! meiosis GO:0007126 96 61 2,000 0,01314616 0,06689418 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 2,000 0,01314616 0,06674651 ! urogenital system development GO:0001655 101 61 2,000 0,01314616 0,0665995 ! homeostasis of number of cells GO:0048872 84 61 2,000 0,01314616 0,06645312 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 0,01342484 0,06771301 ! leukocyte adhesion GO:0007159 38 22 1,000 0,01342484 0,06756484 ! molting cycle process GO:0022404 40 22 1,000 0,01342484 0,06741732 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 0,01342484 0,06727044 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 0,01342484 0,0671242 ! vasculogenesis GO:0001570 33 22 1,000 0,01342484 0,0669786 ! ureteric bud development GO:0001657 32 22 1,000 0,01342484 0,06683362 ! membrane depolarization GO:0051899 35 22 1,000 0,01342484 0,06668927 ! leukocyte homeostasis GO:0001776 33 22 1,000 0,01342484 0,06654554 ! blastocyst development GO:0001824 37 22 1,000 0,01342484 0,06640244 ! meiotic cell cycle GO:0051321 97 62 2,000 0,01373456 0,0677886 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 0,01462643 0,07203597 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01462643 0,07188204 ! myelination GO:0042552 35 23 1,000 0,01462643 0,07172878 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01462643 0,07157616 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 0,01462643 0,0714242 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 0,01462643 0,07127287 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 0,01462643 0,07112219 ! regulation of viral reproduction GO:0050792 32 23 1,000 0,01462643 0,07097215 ! lymphocyte proliferation GO:0046651 36 23 1,000 0,01462643 0,07082273 ! cellular response to oxidative stress GO:0034599 33 23 1,000 0,01462643 0,07067394 ! group transfer coenzyme metabolic process GO:0006752 28 23 1,000 0,01462643 0,07052578 ! response to molecule of bacterial origin GO:0002237 30 23 1,000 0,01462643 0,07037824 ! reproductive structure development GO:0048608 90 65 2,000 0,01558871 0,07485183 ! regulation of caspase activity GO:0043281 97 65 2,000 0,01558871 0,07469589 ! pyruvate metabolic process GO:0006090 29 24 1,000 0,01587264 0,07589829 ! fat cell differentiation GO:0045444 37 24 1,000 0,01587264 0,07574083 ! response to toxin GO:0009636 38 24 1,000 0,01587264 0,07558402 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,01587264 0,07542785 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01587264 0,07527233 ! cell-substrate adhesion GO:0031589 121 66 2,000 0,01623654 0,07683961 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01689933 0,07981204 ! male gonad development GO:0008584 33 25 1,000 0,01716268 0,08088969 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01716268 0,08072427 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01716268 0,08055953 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 1,000 0,01716268 0,08039546 GO:0032943|mononuclear cell proliferation, ! development of primary sexual characteristics GO:0045137 92 68 2,000 0,0175771 0,08216936 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,01849577 0,0862886 ! post-embryonic development GO:0009791 42 26 1,000 0,01849577 0,08611392 ! multicellular organismal catabolic process GO:0044243 32 26 1,000 0,01849577 0,08593996 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,01849577 0,08576669 ! regulation of catabolic process GO:0009894 106 70 2,000 0,01897767 0,08782422 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 0,01970051 0,09098628 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 0,01970051 0,09080395 ! response to ionizing radiation GO:0010212 47 27 1,000 0,01987115 0,09140728 ! lipid oxidation GO:0034440 38 27 1,000 0,01987115 0,09122483 GO:0019395|fatty acid oxidation, ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,01987115 0,09104311 ! negative regulation of protein transport GO:0051224 49 27 1,000 0,01987115 0,09086211 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,02043841 0,0932705 ! negative regulation of organelle organization GO:0010639 115 72 2,000 0,02043841 0,09308581 ! regulation of blood pressure GO:0008217 107 73 2,000 0,02119137 0,09632441 ! tube morphogenesis GO:0035239 118 73 2,000 0,02119137 0,09613442 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,02128805 0,0963829 ! erythrocyte differentiation GO:0030218 38 28 1,000 0,02128805 0,09619354 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,02128805 0,09600492 ! ensheathment of neurons GO:0007272 43 28 1,000 0,02128805 0,09581705 GO:0008366|axon ensheathment, ! blood coagulation GO:0007596 116 75 2,000 0,02274252 0,10216367 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 2,000 0,02274252 0,10196452 ! regulation of ligase activity GO:0051340 114 75 2,000 0,02274252 0,10176614 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,02274572 0,10158285 ! ovulation cycle process GO:0022602 41 29 1,000 0,02274572 0,10138598 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,02274572 0,10118988 ! telencephalon development GO:0021537 52 29 1,000 0,02274572 0,10099453 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,02274572 0,10079993 ! tissue homeostasis GO:0001894 42 29 1,000 0,02274572 0,10060609 GO:0048871|multicellular organismal homeostasis, ! regulation of protein transport GO:0051223 114 76 2,000 0,02354071 0,10392253 GO:0070201|regulation of establishment of protein localization, ! collagen metabolic process GO:0032963 40 30 1,000 0,02424344 0,10681974 ! spindle organization GO:0007051 37 30 1,000 0,02424344 0,10661549 ! ovulation cycle GO:0042698 43 30 1,000 0,02424344 0,10641203 ! fatty acid catabolic process GO:0009062 43 30 1,000 0,02424344 0,10620934 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,02424344 0,10600742 ! response to heat GO:0009408 41 30 1,000 0,02424344 0,10580627 ! sex differentiation GO:0007548 105 77 2,000 0,02435398 0,10608739 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,02578045 0,11208893 ! mammary gland development GO:0030879 57 31 1,000 0,02578045 0,11187744 ! odontogenesis GO:0042476 50 31 1,000 0,02578045 0,11166675 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,02578045 0,11145685 ! segmentation GO:0035282 41 31 1,000 0,02578045 0,11124773 ! metanephros development GO:0001656 58 31 1,000 0,02578045 0,1110394 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,02578045 0,11083185 ! cell fate specification GO:0001708 37 31 1,000 0,02578045 0,11062508 ! biogenic amine biosynthetic process GO:0042401 44 31 1,000 0,02578045 0,11041907 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,02735605 0,11694967 ! meiosis I GO:0007127 52 32 1,000 0,02735605 0,11673269 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02735605 0,11651652 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,02735605 0,11630115 ! hemostasis GO:0007599 125 81 2,000 0,02775759 0,11779051 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 0,02896952 0,12270701 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,02896952 0,12248144 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02896952 0,12225671 ! ear morphogenesis GO:0042471 42 33 1,000 0,02896952 0,12203279 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 1,000 0,02896952 0,1218097 ! female gonad development GO:0008585 49 33 1,000 0,02896952 0,12158742 ! positive regulation of cell development GO:0010720 54 33 1,000 0,02896952 0,12136595 ! lipid homeostasis GO:0055088 55 33 1,000 0,02896952 0,12114528 ! nucleotide catabolic process GO:0009166 46 33 1,000 0,02896952 0,12092542 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,02896952 0,12070635 ! biogenic amine metabolic process GO:0006576 121 83 2,000 0,02954952 0,12290037 ! regulation of defense response GO:0031347 117 84 2,000 0,03046795 0,12649149 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,03046795 0,12626358 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,03062016 0,12666613 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,03062016 0,12643872 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,03062016 0,12621213 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,03062016 0,12598635 ! female gamete generation GO:0007292 43 34 1,000 0,03062016 0,12576137 ! polyol metabolic process GO:0019751 44 34 1,000 0,03062016 0,1255372 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,03062016 0,12531382 ! transcription initiation GO:0006352 118 85 2,000 0,03140131 0,12828246 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 0,03140131 0,12805501 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,03230727 0,13151631 ! maintenance of protein location GO:0045185 65 35 1,000 0,03230727 0,13128395 ! Rho protein signal transduction GO:0007266 51 35 1,000 0,03230727 0,13105241 ! glycogen metabolic process GO:0005977 48 35 1,000 0,03230727 0,13082168 ! pigment metabolic process GO:0042440 61 35 1,000 0,03230727 0,13059177 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,03230727 0,13036266 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 0,03230727 0,13013436 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,03331274 0,13394982 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 2,000 0,03331274 0,13371605 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,03403016 0,13635779 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 1,000 0,03403016 0,13612064 ! neural tube development GO:0021915 50 36 1,000 0,03403016 0,13588432 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,03403016 0,13564882 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 1,000 0,03403016 0,13541413 ! glucan metabolic process GO:0044042 49 36 1,000 0,03403016 0,13518026 GO:0006073|cellular glucan metabolic process, ! carboxylic acid catabolic process GO:0046395 122 88 2,000 0,03429073 0,13598048 GO:0016054|organic acid catabolic process, ! regulation of T cell activation GO:0050863 128 89 2,000 0,03528352 0,1396766 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,03578816 0,14143087 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,03758059 0,14825963 ! monocarboxylic acid transport GO:0015718 62 38 1,000 0,03758059 0,14800576 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,03758059 0,14775276 ! mesenchymal cell development GO:0014031 64 38 1,000 0,03758059 0,14750062 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 1,000 0,03758059 0,14724934 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,0394068 0,15414226 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 1,000 0,0394068 0,15388056 ! developmental growth GO:0048589 62 39 1,000 0,0394068 0,15361974 ! synapse organization GO:0050808 55 39 1,000 0,0394068 0,15335981 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03968637 0,15418692 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03968637 0,15392691 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03968637 0,15366778 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03968637 0,15340951 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03968637 0,15315211 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03968637 0,15289558 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03968637 0,1526399 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03968637 0,15238507 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03968637 0,1521311 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03968637 0,15187797 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03968637 0,15162568 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03968637 0,15137423 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03968637 0,15112361 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03968637 0,15087382 ! tongue development GO:0043586 6 5 0,000 0,03968637 0,15062485 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03968637 0,1503767 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03968637 0,15012937 ! cobalt ion transport GO:0006824 9 5 0,000 0,03968637 0,14988286 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03968637 0,14963715 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03968637 0,14939224 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03968637 0,14914814 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03968637 0,14890483 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03968637 0,14866231 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03968637 0,14842058 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03968637 0,14817964 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03968637 0,14793948 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03968637 0,1477001 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03968637 0,14746148 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03968637 0,14722364 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03968637 0,14698657 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03968637 0,14675026 ! malate metabolic process GO:0006108 7 5 0,000 0,03968637 0,1465147 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03968637 0,1462799 ! behavioral response to pain GO:0048266 7 5 0,000 0,03968637 0,14604585 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03968637 0,14581255 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03968637 0,14558 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03968637 0,14534818 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03968637 0,1451171 ! mating behavior GO:0007617 6 5 0,000 0,03968637 0,14488676 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03968637 0,14465715 ! rhythmic behavior GO:0007622 12 5 0,000 0,03968637 0,14442826 ! copulation GO:0007620 7 5 0,000 0,03968637 0,14420009 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03968637 0,14397265 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03968637 0,14374592 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03968637 0,1435199 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03968637 0,1432946 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03968637 0,14307 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03968637 0,1428461 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03968637 0,1426229 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03968637 0,1424004 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03968637 0,1421786 ! response to protozoan GO:0001562 9 5 0,000 0,03968637 0,14195748 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,03968637 0,14173705 ! lymph vessel development GO:0001945 7 5 0,000 0,03968637 0,1415173 ! endochondral ossification GO:0001958 12 5 0,000 0,03968637 0,14129823 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03968637 0,14107984 ! parathyroid gland development GO:0060017 8 5 0,000 0,03968637 0,14086213 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03968637 0,14064508 ! anagen GO:0042640 6 5 0,000 0,03968637 0,14042871 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03968637 0,14021299 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03968637 0,13999794 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03968637 0,13978355 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03968637 0,13956982 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03968637 0,13935673 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03968637 0,1391443 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03968637 0,13893251 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03968637 0,13872137 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03968637 0,13851086 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03968637 0,138301 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03968637 0,13809177 ! ovulation GO:0030728 6 5 0,000 0,03968637 0,13788317 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03968637 0,1376752 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,03968637 0,13746786 GO:0030033|microvillus assembly, ! response to pH GO:0009268 9 5 0,000 0,03968637 0,13726114 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03968637 0,13705504 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03968637 0,13684956 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03968637 0,1366447 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03968637 0,13644045 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03968637 0,1362368 ! polyol catabolic process GO:0046174 7 5 0,000 0,03968637 0,13603377 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03968637 0,13583134 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03968637 0,13562951 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03968637 0,13542828 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03968637 0,13522764 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03968637 0,1350276 ! urea metabolic process GO:0019627 6 5 0,000 0,03968637 0,13482815 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03968637 0,13462929 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03968637 0,13443101 ! neutrophil activation GO:0042119 5 5 0,000 0,03968637 0,13423332 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03968637 0,13403621 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03968637 0,13383968 ! response to food GO:0032094 5 5 0,000 0,03968637 0,13364372 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03968637 0,13344833 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03968637 0,13325352 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03968637 0,13305927 ! forebrain neuron development GO:0021884 7 5 0,000 0,03968637 0,13286559 ! melanosome organization GO:0032438 7 5 0,000 0,03968637 0,13267247 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03968637 0,13247991 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03968637 0,13228791 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03968637 0,13209647 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03968637 0,13190558 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03968637 0,13171524 ! nucleoside transport GO:0015858 6 5 0,000 0,03968637 0,13152545 ! nucleoside salvage GO:0043174 7 5 0,000 0,03968637 0,1313362 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03968637 0,1311475 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03968637 0,13095934 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03968637 0,13077172 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03968637 0,13058463 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03968637 0,13039808 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03968637 0,13021207 ! depyrimidination GO:0045008 8 5 0,000 0,03968637 0,13002658 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03968637 0,12984162 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03968637 0,12965719 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03968637 0,12947328 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03968637 0,12928989 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03968637 0,12910701 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03968637 0,12892466 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03968637 0,12874282 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03968637 0,12856149 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03968637 0,12838067 ! centrosome duplication GO:0051298 5 5 0,000 0,03968637 0,12820036 ! response to UV-C GO:0010225 6 5 0,000 0,03968637 0,12802056 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03968637 0,12784126 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03968637 0,12766246 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03968637 0,12748416 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03968637 0,12730636 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03968637 0,12712905 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03968637 0,12695224 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03968637 0,12677592 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03968637 0,12660008 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03968637 0,12642474 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03968637 0,12624987 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03968637 0,1260755 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03968637 0,1259016 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03968637 0,12572818 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03968637 0,12555524 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03968637 0,12538277 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03968637 0,12521078 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03968637 0,12503926 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03968637 0,12486821 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03968637 0,12469762 ! histone demethylation GO:0016577 9 5 0,000 0,03968637 0,1245275 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03968637 0,12435785 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03968637 0,12418865 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03968637 0,12401992 ! enteric nervous system development GO:0048484 8 5 0,000 0,03968637 0,12385164 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03968637 0,12368382 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03968637 0,12351645 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03968637 0,12334954 ! transcription termination GO:0006353 8 5 0,000 0,03968637 0,12318308 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03968637 0,12301706 ! plasminogen activation GO:0031639 5 5 0,000 0,03968637 0,12285149 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,03968637 0,12268637 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03968637 0,12252169 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03968637 0,12235745 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03968637 0,12219365 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03968637 0,12203029 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03968637 0,12186737 ! apical protein localization GO:0045176 6 5 0,000 0,03968637 0,12170488 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03968637 0,12154282 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03968637 0,1213812 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03968637 0,12122 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03968637 0,12105923 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03968637 0,12089889 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03968637 0,12073897 ! glial cell migration GO:0008347 10 5 0,000 0,03968637 0,12057947 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03968637 0,12042039 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03968637 0,12026174 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03968637 0,1201035 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03968637 0,11994568 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03968637 0,11978827 ! neural plate development GO:0001840 6 5 0,000 0,03968637 0,11963127 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03968637 0,11947468 ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03968637 0,11931851 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03968637 0,11916274 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03968637 0,11900738 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03968637 0,11885242 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03968637 0,11869787 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03968637 0,11854371 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03968637 0,11838996 ! spindle assembly GO:0051225 5 5 0,000 0,03968637 0,1182366 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03968637 0,11808365 GO:0022011|myelination in the peripheral nervous system, ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03968637 0,11793108 ! organ regeneration GO:0031100 7 5 0,000 0,03968637 0,11777891 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03968637 0,11762714 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03968637 0,11747575 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03968637 0,11732475 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03968637 0,11717415 GO:0055081|anion homeostasis, ! response to oxidative stress GO:0006979 141 94 2,000 0,0404681 0,11932901 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,04126614 0,1215264 ! T cell differentiation GO:0030217 65 40 1,000 0,04126614 0,12137099 ! double-strand break repair GO:0006302 67 40 1,000 0,04126614 0,12121598 ! B cell differentiation GO:0030183 62 40 1,000 0,04126614 0,12106137 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,04126614 0,12090715 ! carboxylic acid transport GO:0046942 147 95 2,000 0,04154881 0,12158048 GO:0015849|organic acid transport, ! protein modification by small protein conjugation or removal GO:0070647 148 96 2,000 0,04264399 0,12462666 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,04315795 0,12596863 ! glucose transport GO:0015758 52 41 1,000 0,04315795 0,12580897 ! endosome transport GO:0016197 71 41 1,000 0,04315795 0,12564972 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,04315795 0,12549087 ! biopolymer methylation GO:0043414 62 41 1,000 0,04315795 0,12533242 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 2,000 0,0437536 0,12690201 ! mitochondrial transport GO:0006839 60 42 1,000 0,0450816 0,13058901 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,0450816 0,13042475 ! hexose transport GO:0008645 54 42 1,000 0,0450816 0,1302609 GO:0015749|monosaccharide transport, ! icosanoid metabolic process GO:0006690 61 42 1,000 0,0450816 0,13009746 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,0450816 0,12993443 ! extracellular structure organization GO:0043062 156 99 2,000 0,04601587 0,1324612 ! positive regulation of binding GO:0051099 59 43 1,000 0,04703646 0,13522983 ! vesicle organization GO:0016050 79 43 1,000 0,04703646 0,13506101 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,04703646 0,1348926 ! methylation GO:0032259 64 43 1,000 0,04703646 0,13472461 ! regulation of body fluid levels GO:0050878 154 100 2,000 0,0471684 0,13493448 ! Ras protein signal transduction GO:0007265 162 100 2,000 0,0471684 0,13476686 ! tRNA transcription GO:0009304 11 6 0,000 0,04743394 0,1353574 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04743394 0,13518967 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04743394 0,13502235 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04743394 0,13485545 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04743394 0,13468897 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04743394 0,13452289 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04743394 0,13435722 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04743394 0,13419196 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04743394 0,1340271 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04743394 0,13386265 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04743394 0,13369861 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04743394 0,13353496 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04743394 0,13337171 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04743394 0,13320887 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,04743394 0,13304642 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04743394 0,13288436 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04743394 0,1327227 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04743394 0,13256144 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04743394 0,13240056 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04743394 0,13224008 ! neuron adhesion GO:0007158 9 6 0,000 0,04743394 0,13207998 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04743394 0,13192027 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04743394 0,13176094 ! signal peptide processing GO:0006465 8 6 0,000 0,04743394 0,13160201 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04743394 0,13144345 ! mRNA stabilization GO:0048255 15 6 0,000 0,04743394 0,13128527 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04743394 0,13112748 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04743394 0,13097006 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04743394 0,13081302 ! opsonization GO:0008228 8 6 0,000 0,04743394 0,13065636 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04743394 0,13050007 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04743394 0,13034416 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04743394 0,13018862 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04743394 0,13003345 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04743394 0,12987865 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04743394 0,12972421 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04743394 0,12957015 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04743394 0,12941644 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04743394 0,12926311 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04743394 0,12911013 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04743394 0,12895752 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04743394 0,12880527 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04743394 0,12865338 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04743394 0,12850184 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04743394 0,12835066 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04743394 0,12819984 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04743394 0,12804937 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04743394 0,12789925 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04743394 0,12774949 ! thymic T cell selection GO:0045061 12 6 0,000 0,04743394 0,12760007 ! protein lipoylation GO:0009249 10 6 0,000 0,04743394 0,12745101 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04743394 0,12730229 ! drug transport GO:0015893 6 6 0,000 0,04743394 0,12715392 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04743394 0,12700589 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04743394 0,12685821 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04743394 0,12671087 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04743394 0,12656388 ! histidine metabolic process GO:0006547 6 6 0,000 0,04743394 0,12641722 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04743394 0,12627091 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04743394 0,12612493 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04743394 0,12597929 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04743394 0,12583398 ! adenohypophysis development GO:0021984 10 6 0,000 0,04743394 0,12568901 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04743394 0,12554438 ! hyperosmotic response GO:0006972 8 6 0,000 0,04743394 0,12540007 ! microtubule nucleation GO:0007020 10 6 0,000 0,04743394 0,1252561 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04743394 0,12511246 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04743394 0,12496914 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04743394 0,12482616 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04743394 0,1246835 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,04743394 0,12454117 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04743394 0,12439916 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04743394 0,12425747 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04743394 0,12411611 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04743394 0,12397507 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04743394 0,12383435 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04743394 0,12369395 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04743394 0,12355386 ! neuron apoptosis GO:0051402 8 6 0,000 0,04743394 0,1234141 ! organic alcohol transport GO:0015850 9 6 0,000 0,04743394 0,12327465 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04743394 0,12313551 ! male sex determination GO:0030238 9 6 0,000 0,04743394 0,12299669 ! carnitine transport GO:0015879 8 6 0,000 0,04743394 0,12285818 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04743394 0,12271998 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04743394 0,12258209 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04743394 0,12244451 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04743394 0,12230724 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04743394 0,12217028 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04743394 0,12203363 ! parturition GO:0007567 12 6 0,000 0,04743394 0,12189728 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04743394 0,12176123 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04743394 0,12162549 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04743394 0,12149005 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04743394 0,12135491 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,04743394 0,12122007 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04743394 0,12108553 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04743394 0,12095129 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04743394 0,12081734 ! astrocyte development GO:0014002 14 6 0,000 0,04743394 0,1206837 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04743394 0,12055034 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04743394 0,12041729 ! interaction with symbiont GO:0051702 8 6 0,000 0,04743394 0,12028452 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04743394 0,12015205 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04743394 0,12001987 ! eating behavior GO:0042755 6 6 0,000 0,04743394 0,11988798 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04743394 0,11975638 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04743394 0,11962507 ! response to copper ion GO:0046688 9 6 0,000 0,04743394 0,11949404 ! DNA topological change GO:0006265 8 6 0,000 0,04743394 0,11936331 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04743394 0,11923285 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04743394 0,11910269 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04743394 0,11897281 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04743394 0,1188432 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04743394 0,11871389 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04743394 0,11858485 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04743394 0,11845609 ! gas homeostasis GO:0033483 11 6 0,000 0,04743394 0,11832762 ! hair follicle maturation GO:0048820 7 6 0,000 0,04743394 0,11819942 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04743394 0,1180715 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04743394 0,11794385 ! Schwann cell development GO:0014044 14 6 0,000 0,04743394 0,11781648 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04743394 0,11768939 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04743394 0,11756257 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04743394 0,11743602 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04743394 0,11730974 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04743394 0,11718374 ! histone ubiquitination GO:0016574 7 6 0,000 0,04743394 0,11705801 ! regulation of meiosis GO:0040020 10 6 0,000 0,04743394 0,11693254 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04743394 0,11680735 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04743394 0,11668242 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04743394 0,11655776 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04743394 0,11643336 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04743394 0,11630923 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04743394 0,11618537 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04743394 0,11606177 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04743394 0,11593843 ! receptor internalization GO:0031623 9 6 0,000 0,04743394 0,11581535 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04743394 0,11569254 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04743394 0,11556998 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04743394 0,11544768 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,04743394 0,11532565 ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04743394 0,11520387 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04743394 0,11508234 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04743394 0,11496108 ! axonal fasciculation GO:0007413 9 6 0,000 0,04743394 0,11484007 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04743394 0,11471931 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04743394 0,1145988 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04743394 0,11447855 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04743394 0,11435856 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04743394 0,11423881 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04743394 0,11411931 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04743394 0,11400006 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04743394 0,11388107 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04743394 0,11376232 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04743394 0,11364381 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04743394 0,11352556 ! adult feeding behavior GO:0008343 6 6 0,000 0,04743394 0,11340755 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04743394 0,11328978 ! blastocyst growth GO:0001832 15 6 0,000 0,04743394 0,11317226 ! pigment granule transport GO:0051904 12 6 0,000 0,04743394 0,11305499 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04743394 0,11293795 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04743394 0,11282116 ! catecholamine transport GO:0051937 7 6 0,000 0,04743394 0,11270461 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04743394 0,1125883 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04743394 0,11247223 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04743394 0,1123564 ! protein prenylation GO:0018342 10 6 0,000 0,04743394 0,1122408 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04743394 0,11212545 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04743394 0,11201033 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04743394 0,11189545 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04743394 0,1117808 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04743394 0,11166639 ! regulation of action potential GO:0001508 71 44 1,000 0,04902192 0,11528672 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,04902192 0,11516896 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,04902192 0,11505144 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,05103735 0,11965944 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,05308216 0,12432686 ! unsaturated fatty acid metabolic process GO:0033559 66 46 1,000 0,05308216 0,12420038 ! regulation of ossification GO:0030278 71 46 1,000 0,05308216 0,12407416 ! histone modification GO:0016570 68 46 1,000 0,05308216 0,1239482 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,05511944 0,12857476 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,05511944 0,12844449 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05511944 0,12831449 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,05511944 0,12818475 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05511944 0,12805527 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05511944 0,12792605 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05511944 0,12779709 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05511944 0,12766839 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05511944 0,12753995 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05511944 0,12741177 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05511944 0,12728385 ! reproductive behavior GO:0019098 12 7 0,000 0,05511944 0,12715618 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,05511944 0,12702877 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05511944 0,12690162 ! oligopeptide transport GO:0006857 11 7 0,000 0,05511944 0,12677471 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05511944 0,12664807 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05511944 0,12652167 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,05511944 0,12639553 ! RNA methylation GO:0001510 11 7 0,000 0,05511944 0,12626964 ! pericardium development GO:0060039 8 7 0,000 0,05511944 0,12614399 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05511944 0,1260186 ! fibril organization GO:0043206 13 7 0,000 0,05511944 0,12589346 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05511944 0,12576857 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05511944 0,12564392 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,05511944 0,12551952 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05511944 0,12539537 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05511944 0,12527146 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05511944 0,12514779 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05511944 0,12502437 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05511944 0,1249012 ! chemosensory behavior GO:0007635 9 7 0,000 0,05511944 0,12477826 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,05511944 0,12465557 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,05511944 0,12453312 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,05511944 0,12441091 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05511944 0,12428894 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05511944 0,1241672 ! reflex GO:0060004 12 7 0,000 0,05511944 0,12404571 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05511944 0,12392445 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05511944 0,12380343 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05511944 0,12368265 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05511944 0,1235621 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05511944 0,12344179 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05511944 0,12332171 ! spinal cord patterning GO:0021511 7 7 0,000 0,05511944 0,12320186 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,05511944 0,12308225 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,05511944 0,12296287 ! adrenal gland development GO:0030325 17 7 0,000 0,05511944 0,12284372 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05511944 0,1227248 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,05511944 0,12260611 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05511944 0,12248765 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05511944 0,12236942 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05511944 0,12225141 ! endosome organization GO:0007032 10 7 0,000 0,05511944 0,12213364 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05511944 0,12201609 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05511944 0,12189876 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05511944 0,12178167 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05511944 0,12166479 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,05511944 0,12154814 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05511944 0,12143172 ! galactose metabolic process GO:0006012 10 7 0,000 0,05511944 0,12131552 ! vesicle fusion GO:0006906 15 7 0,000 0,05511944 0,12119954 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05511944 0,12108378 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,05511944 0,12096824 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05511944 0,12085292 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,05511944 0,12073782 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05511944 0,12062294 ! retinol metabolic process GO:0042572 9 7 0,000 0,05511944 0,12050828 ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,05511944 0,12039384 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05511944 0,12027962 ! rRNA modification GO:0000154 12 7 0,000 0,05511944 0,12016561 ! protein heterooligomerization GO:0051291 10 7 0,000 0,05511944 0,12005181 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05511944 0,11993823 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,05511944 0,11982487 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05511944 0,11971172 ! intermediate filament organization GO:0045109 11 7 0,000 0,05511944 0,11959879 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05511944 0,11948606 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,05511944 0,11937355 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05511944 0,11926126 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,05511944 0,11914917 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,05511944 0,11903729 ! response to tropane GO:0014073 13 7 0,000 0,05511944 0,11892562 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! melanosome localization GO:0032400 10 7 0,000 0,05511944 0,11881417 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05511944 0,11870292 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05511944 0,11859187 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,05511944 0,11848104 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05511944 0,11837041 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05511944 0,11825999 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05511944 0,11814978 ! mast cell activation GO:0045576 9 7 0,000 0,05511944 0,11803977 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05511944 0,11792997 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,05511944 0,11782037 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05511944 0,11771097 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05511944 0,11760178 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,05511944 0,11749278 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,05511944 0,11738399 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05511944 0,11727541 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,05511944 0,11716702 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05511944 0,11705883 ! regulation of lipid transport GO:0032368 13 7 0,000 0,05511944 0,11695084 ! response to tumor cell GO:0002347 12 7 0,000 0,05511944 0,11684305 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05511944 0,11673546 ! neuroblast proliferation GO:0007405 13 7 0,000 0,05511944 0,11662807 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05511944 0,11652088 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,05511944 0,11641388 ! diuresis GO:0030146 12 7 0,000 0,05511944 0,11630708 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05511944 0,11620047 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,05511944 0,11609406 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05511944 0,11598784 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,05511944 0,11588182 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05511944 0,11577599 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05511944 0,11567036 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05511944 0,11556492 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05511944 0,11545967 ! lymph node development GO:0048535 9 7 0,000 0,05511944 0,11535461 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05511944 0,11524974 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05511944 0,11514506 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05511944 0,11504058 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05511944 0,11493628 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05511944 0,11483217 ! ATP catabolic process GO:0006200 10 7 0,000 0,05511944 0,11472825 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05511944 0,11462452 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05511944 0,11452097 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05511944 0,11441761 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05511944 0,11431444 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05511944 0,11421145 ! muscle adaptation GO:0043500 12 7 0,000 0,05511944 0,11410865 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05511944 0,11400604 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05511944 0,11390361 ! retina homeostasis GO:0001895 9 7 0,000 0,05511944 0,11380136 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05511944 0,1136993 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05511944 0,11359741 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,05511944 0,11349572 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,05511944 0,1133942 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05511944 0,11329286 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,05511944 0,11319171 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05511944 0,11309074 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,05515575 0,11306437 ! covalent chromatin modification GO:0016569 75 47 1,000 0,05515575 0,11296369 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,05515575 0,11286319 ! response to temperature stimulus GO:0009266 62 48 1,000 0,05725752 0,11705982 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,05725752 0,11695586 ! germ cell development GO:0007281 68 49 1,000 0,0593869 0,12119776 ! heterocycle catabolic process GO:0046700 72 49 1,000 0,0593869 0,12109031 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,0593869 0,12098306 ! maintenance of location GO:0051235 84 49 1,000 0,0593869 0,12087599 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,06154331 0,12515438 ! membrane fusion GO:0006944 80 50 1,000 0,06154331 0,12504382 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,06154331 0,12493346 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 1,000 0,06154331 0,12482329 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,06274337 0,12714516 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,06274337 0,12703323 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,06274337 0,1269215 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,06274337 0,12680997 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,06274337 0,12669864 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,06274337 0,1265875 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,06274337 0,12647656 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,06274337 0,12636581 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,06274337 0,12625525 ! phosphate transport GO:0006817 10 8 0,000 0,06274337 0,12614489 ! N-glycan processing GO:0006491 12 8 0,000 0,06274337 0,12603472 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,06274337 0,12592474 ! UTP metabolic process GO:0046051 8 8 0,000 0,06274337 0,12581495 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,06274337 0,12570536 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,06274337 0,12559595 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,06274337 0,12548674 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,06274337 0,12537772 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,06274337 0,12526888 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,06274337 0,12516024 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,06274337 0,12505178 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,06274337 0,12494351 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06274337 0,12483542 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,06274337 0,12472753 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,06274337 0,12461982 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,06274337 0,1245123 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,06274337 0,12440496 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,06274337 0,1242978 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,06274337 0,12419084 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,06274337 0,12408405 ! astrocyte differentiation GO:0048708 16 8 0,000 0,06274337 0,12397745 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,06274337 0,12387103 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,06274337 0,1237648 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,06274337 0,12365874 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,06274337 0,12355287 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,06274337 0,12344718 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06274337 0,12334167 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,06274337 0,12323634 ! macrophage activation GO:0042116 12 8 0,000 0,06274337 0,12313119 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,06274337 0,12302622 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,06274337 0,12292142 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,06274337 0,12281681 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,06274337 0,12271237 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,06274337 0,12260811 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,06274337 0,12250403 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,06274337 0,12240013 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,06274337 0,1222964 ! ruffle organization GO:0031529 11 8 0,000 0,06274337 0,12219285 ! osteoblast development GO:0002076 13 8 0,000 0,06274337 0,12208947 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,06274337 0,12198626 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,06274337 0,12188324 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,06274337 0,12178038 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,06274337 0,1216777 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,06274337 0,12157519 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,06274337 0,12147285 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,06274337 0,12137069 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,06274337 0,1212687 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,06274337 0,12116688 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,06274337 0,12106523 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,06274337 0,12096375 ! oligodendrocyte development GO:0014003 8 8 0,000 0,06274337 0,12086244 ! segment specification GO:0007379 10 8 0,000 0,06274337 0,1207613 ! cellular extravasation GO:0045123 11 8 0,000 0,06274337 0,12066033 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,06274337 0,12055952 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,06274337 0,12045889 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,06274337 0,12035842 ! snRNA metabolic process GO:0016073 10 8 0,000 0,06274337 0,12025813 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,06274337 0,12015799 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,06274337 0,12005803 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,06274337 0,11995823 ! nucleosome disassembly GO:0006337 12 8 0,000 0,06274337 0,1198586 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,06274337 0,11975913 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,06274337 0,11965983 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,06274337 0,11956069 ! icosanoid secretion GO:0032309 12 8 0,000 0,06274337 0,11946171 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06274337 0,1193629 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,06274337 0,11926426 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,06274337 0,11916577 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,06274337 0,11906745 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,06274337 0,11896929 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,06274337 0,11887129 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,06274337 0,11877346 ! sterol catabolic process GO:0016127 9 8 0,000 0,06274337 0,11867578 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,06274337 0,11857827 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,06274337 0,11848091 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,06274337 0,11838372 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,06274337 0,11828668 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,06274337 0,1181898 ! prophase GO:0051324 11 8 0,000 0,06274337 0,11809309 ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,06274337 0,11799653 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,06274337 0,11790012 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,06274337 0,11780388 ! hormone catabolic process GO:0042447 13 8 0,000 0,06274337 0,11770779 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,06274337 0,11761186 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,06274337 0,11751608 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,06274337 0,11742046 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,06274337 0,117325 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,06274337 0,11722969 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,06274337 0,11713454 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06274337 0,11703954 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,06274337 0,11694469 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,06274337 0,11685 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,06274337 0,11675546 ! lamellipodium assembly GO:0030032 9 8 0,000 0,06274337 0,11666108 ! regulation of embryonic development GO:0045995 16 8 0,000 0,06274337 0,11656684 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06274337 0,11647276 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,06274337 0,11637883 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,06274337 0,11628505 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,06372618 0,11801144 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,06372618 0,1179165 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,06372618 0,11782171 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,06372618 0,11772708 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,06593495 0,12170978 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,06816907 0,12573285 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,06816907 0,12563211 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,06816907 0,12553152 ! kidney development GO:0001822 90 53 1,000 0,06816907 0,12543109 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,07030622 0,12926003 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,07030622 0,12915679 ! telencephalon cell migration GO:0022029 16 9 0,000 0,07030622 0,12905371 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,07030622 0,1289508 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,07030622 0,12884805 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,07030622 0,12874546 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,07030622 0,12864304 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,07030622 0,12854078 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,07030622 0,12843868 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,07030622 0,12833674 ! elastic fiber assembly GO:0048251 13 9 0,000 0,07030622 0,12823497 ! social behavior GO:0035176 14 9 0,000 0,07030622 0,12813336 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,07030622 0,12803191 ! artery development GO:0060840 19 9 0,000 0,07030622 0,12793062 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,07030622 0,12782949 ! regulation of glycolysis GO:0006110 15 9 0,000 0,07030622 0,12772851 ! protein complex disassembly GO:0043241 17 9 0,000 0,07030622 0,1276277 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,07030622 0,12752705 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,07030622 0,12742656 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,07030622 0,12732622 ! lung alveolus development GO:0048286 17 9 0,000 0,07030622 0,12722604 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,07030622 0,12712602 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,07030622 0,12702616 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,07030622 0,12692645 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,07030622 0,1268269 ! ventral spinal cord development GO:0021517 11 9 0,000 0,07030622 0,12672751 ! protein targeting to ER GO:0045047 19 9 0,000 0,07030622 0,12662827 ! endoderm development GO:0007492 12 9 0,000 0,07030622 0,12652919 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,07030622 0,12643026 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,07030622 0,12633148 ! arginine catabolic process GO:0006527 10 9 0,000 0,07030622 0,12623286 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,07030622 0,1261344 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,07030622 0,12603609 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,07030622 0,12593793 ! V(D)J recombination GO:0033151 12 9 0,000 0,07030622 0,12583992 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,07030622 0,12574207 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,07030622 0,12564437 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,07030622 0,12554682 ! mannose metabolic process GO:0006013 9 9 0,000 0,07030622 0,12544942 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,07030622 0,12535217 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,07030622 0,12525507 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,07030622 0,12515813 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,07030622 0,12506133 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,07030622 0,12496468 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,07030622 0,12486818 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,07030622 0,12477184 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,07030622 0,12467564 ! blastoderm segmentation GO:0007350 11 9 0,000 0,07030622 0,12457958 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,07030622 0,12448368 ! DNA ligation GO:0006266 14 9 0,000 0,07030622 0,12438792 ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,07030622 0,12429231 ! erythrocyte development GO:0048821 11 9 0,000 0,07030622 0,12419685 ! renal water homeostasis GO:0003091 14 9 0,000 0,07030622 0,12410153 ! postreplication repair GO:0006301 11 9 0,000 0,07030622 0,12400636 ! mRNA cleavage GO:0006379 13 9 0,000 0,07030622 0,12391134 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,07030622 0,12381646 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,07030622 0,12372173 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,07030622 0,12362714 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,07030622 0,1235327 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,07030622 0,1234384 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,07030622 0,12334424 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,07030622 0,12325023 ! acid secretion GO:0046717 14 9 0,000 0,07030622 0,12315636 ! musculoskeletal movement GO:0050881 11 9 0,000 0,07030622 0,12306263 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,07030622 0,12296905 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,07030622 0,12287561 ! purine base metabolic process GO:0006144 18 9 0,000 0,07030622 0,12278231 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,07030622 0,12268915 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,07030622 0,12259613 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,07030622 0,12250326 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,07030622 0,12241052 ! detection of calcium ion GO:0005513 13 9 0,000 0,07030622 0,12231793 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,07030622 0,12222547 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,07030622 0,12213316 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,07030622 0,12204098 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,07030622 0,12194894 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,07030622 0,12185704 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,07030622 0,12176529 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,07030622 0,12167366 ! prepulse inhibition GO:0060134 14 9 0,000 0,07030622 0,12158218 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,07030622 0,12149083 ! insulin secretion GO:0030073 17 9 0,000 0,07030622 0,12139962 ! sequestering of metal ion GO:0051238 11 9 0,000 0,07030622 0,12130855 ! establishment of cell polarity GO:0030010 12 9 0,000 0,07030622 0,12121762 ! localization within membrane GO:0051668 15 9 0,000 0,07030622 0,12112682 ! amino acid transport GO:0006865 84 54 1,000 0,070428 0,12124581 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,070428 0,12115512 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,070428 0,12106457 ! detection of external stimulus GO:0009581 66 54 1,000 0,070428 0,12097416 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,070428 0,12088388 ! cellular amino acid catabolic process GO:0009063 74 54 1,000 0,070428 0,12079373 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,070428 0,12070372 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,07501811 0,1284748 ! carbohydrate transport GO:0008643 74 57 1,000 0,07734824 0,13236679 ! coenzyme biosynthetic process GO:0009108 67 57 1,000 0,07734824 0,13226837 ! secondary metabolic process GO:0019748 84 57 1,000 0,07734824 0,13217011 ! gonad development GO:0008406 79 57 1,000 0,07734824 0,13207198 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07780847 0,13275925 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07780847 0,13266084 ! neuron fate specification GO:0048665 11 10 0,000 0,07780847 0,13256257 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07780847 0,13246445 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,07780847 0,13236648 ! thyroid gland development GO:0030878 19 10 0,000 0,07780847 0,13226864 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,07780847 0,13217096 ! synapsis GO:0007129 13 10 0,000 0,07780847 0,13207341 GO:0070192|chromosome organization involved in meiosis, ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07780847 0,13197601 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,07780847 0,13187876 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07780847 0,13178165 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,07780847 0,13168468 ! phospholipid efflux GO:0033700 16 10 0,000 0,07780847 0,13158785 ! blood vessel remodeling GO:0001974 21 10 0,000 0,07780847 0,13149116 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,07780847 0,13139462 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07780847 0,13129822 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07780847 0,13120196 ! pathogenesis GO:0009405 13 10 0,000 0,07780847 0,13110584 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07780847 0,13100986 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07780847 0,13091403 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07780847 0,13081833 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,07780847 0,13072277 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07780847 0,13062735 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07780847 0,13053207 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07780847 0,13043694 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07780847 0,13034193 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07780847 0,13024707 ! response to X-ray GO:0010165 16 10 0,000 0,07780847 0,13015235 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07780847 0,13005776 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07780847 0,12996331 ! forebrain cell migration GO:0021885 17 10 0,000 0,07780847 0,12986899 ! lipid digestion GO:0044241 15 10 0,000 0,07780847 0,12977482 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07780847 0,12968078 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,07780847 0,12958688 ! UV protection GO:0009650 14 10 0,000 0,07780847 0,12949311 ! entry into host cell GO:0030260 20 10 0,000 0,07780847 0,12939948 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07780847 0,12930598 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07780847 0,12921262 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,07780847 0,12911939 ! regulation of bone resorption GO:0045124 24 10 0,000 0,07780847 0,1290263 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07780847 0,12893334 ! regulation of organ growth GO:0046620 11 10 0,000 0,07780847 0,12884051 ! response to dsRNA GO:0043331 18 10 0,000 0,07780847 0,12874782 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07780847 0,12865527 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07780847 0,12856284 ! embryonic axis specification GO:0000578 12 10 0,000 0,07780847 0,12847055 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07780847 0,12837839 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,07780847 0,12828636 ! cranial nerve development GO:0021545 12 10 0,000 0,07780847 0,12819447 ! fucose catabolic process GO:0019317 16 10 0,000 0,07780847 0,1281027 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,07780847 0,12801107 ! protein sumoylation GO:0016925 12 10 0,000 0,07780847 0,12791957 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07780847 0,1278282 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07780847 0,12773696 ! zymogen activation GO:0031638 14 10 0,000 0,07780847 0,12764585 ! salivary gland development GO:0007431 22 10 0,000 0,07780847 0,12755486 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07780847 0,12746401 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07780847 0,12737329 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,07780847 0,1272827 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07780847 0,12719224 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,07780847 0,1271019 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07780847 0,12701169 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07780847 0,12692161 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07780847 0,12683166 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,07780847 0,12674184 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,07780847 0,12665214 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07780847 0,12656257 ! detection of bacterium GO:0016045 10 10 0,000 0,07780847 0,12647313 ! embryonic gut development GO:0048566 11 10 0,000 0,07780847 0,12638381 ! activation of innate immune response GO:0002218 10 10 0,000 0,07780847 0,12629462 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07780847 0,12620555 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,07780847 0,12611661 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07780847 0,1260278 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07780847 0,12593911 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,08207607 0,13275313 ! activation of MAPK activity GO:0000187 84 59 1,000 0,08207607 0,13265984 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,08447274 0,13643771 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,08447274 0,13634197 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,08447274 0,13624636 GO:0035113|embryonic appendage morphogenesis, ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,08447274 0,13615088 ! rRNA transcription GO:0009303 17 11 0,000 0,0852506 0,1373084 ! respiratory burst GO:0045730 14 11 0,000 0,0852506 0,13721231 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,0852506 0,13711636 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,0852506 0,13702054 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,0852506 0,13692485 ! virus-host interaction GO:0019048 17 11 0,000 0,0852506 0,1368293 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,0852506 0,13673388 ! RNA polyadenylation GO:0043631 19 11 0,000 0,0852506 0,1366386 ! mating GO:0007618 14 11 0,000 0,0852506 0,13654345 ! T cell proliferation GO:0042098 20 11 0,000 0,0852506 0,13644843 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,0852506 0,13635354 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,0852506 0,13625878 ! bone resorption GO:0045453 16 11 0,000 0,0852506 0,13616416 ! regulated secretory pathway GO:0045055 14 11 0,000 0,0852506 0,13606967 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,0852506 0,1359753 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,0852506 0,13588107 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,0852506 0,13578697 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,0852506 0,135693 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,0852506 0,13559916 ! syncytium formation GO:0006949 15 11 0,000 0,0852506 0,13550545 ! plasma membrane organization GO:0007009 18 11 0,000 0,0852506 0,13541187 ! mitotic spindle organization GO:0007052 15 11 0,000 0,0852506 0,13531842 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,0852506 0,1352251 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,0852506 0,1351319 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,0852506 0,13503883 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,0852506 0,1349459 ! adult heart development GO:0007512 11 11 0,000 0,0852506 0,13485309 ! temperature homeostasis GO:0001659 16 11 0,000 0,0852506 0,1347604 ! L-glutamate transport GO:0015813 16 11 0,000 0,0852506 0,13466785 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,0852506 0,13457542 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,0852506 0,13448312 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,0852506 0,13439094 ! stem cell development GO:0048864 29 11 0,000 0,0852506 0,1342989 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,0852506 0,13420697 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,0852506 0,13411518 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,0852506 0,13402351 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,0852506 0,13393196 ! vasoconstriction GO:0042310 15 11 0,000 0,0852506 0,13384054 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,0852506 0,13374924 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,0852506 0,13365807 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,0852506 0,13356702 ! ribosome assembly GO:0042255 13 11 0,000 0,0852506 0,1334761 ! histone deacetylation GO:0016575 13 11 0,000 0,0852506 0,1333853 ! chromatin silencing GO:0006342 19 11 0,000 0,0852506 0,13329462 ! nucleosome positioning GO:0016584 13 11 0,000 0,0852506 0,13320407 ! regulation of isotype switching GO:0045191 19 11 0,000 0,0852506 0,13311364 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,0852506 0,13302333 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,0852506 0,13293314 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,0852506 0,13284308 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,0852506 0,13275314 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,0852506 0,13266332 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,0852506 0,13257362 ! cholesterol efflux GO:0033344 19 11 0,000 0,0852506 0,13248405 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,0852506 0,13239459 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,0852506 0,13230526 ! germ cell migration GO:0008354 18 11 0,000 0,0852506 0,13221604 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,0852506 0,13212695 ! defense response to fungus GO:0050832 12 11 0,000 0,0852506 0,13203797 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,0852506 0,13194912 ! lysogeny GO:0030069 18 11 0,000 0,0852506 0,13186038 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,0852506 0,13177177 ! acrosome reaction GO:0007340 13 11 0,000 0,0852506 0,13168327 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,0852506 0,13159489 ! extracellular matrix organization GO:0030198 103 61 1,000 0,08689059 0,13403646 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,08689059 0,13394662 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,08689059 0,13385691 ! amine catabolic process GO:0009310 90 62 1,000 0,08932913 0,13752141 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,08932913 0,13742942 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,09178786 0,1411177 ! regulation of lipase activity GO:0060191 109 63 1,000 0,09178786 0,14102343 ! lactation GO:0007595 20 12 0,000 0,0926331 0,14222706 ! reproductive cellular process GO:0048610 14 12 0,000 0,0926331 0,14213218 ! tRNA modification GO:0006400 14 12 0,000 0,0926331 0,14203743 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,0926331 0,1419428 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,0926331 0,1418483 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,0926331 0,14175392 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,0926331 0,14165967 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,0926331 0,14156554 ! non-recombinational repair GO:0000726 19 12 0,000 0,0926331 0,14147154 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,0926331 0,14137766 ! peroxisomal transport GO:0043574 21 12 0,000 0,0926331 0,14128391 ! cartilage condensation GO:0001502 18 12 0,000 0,0926331 0,14119028 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,0926331 0,14109678 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,0926331 0,1410034 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,0926331 0,14091015 ! heart looping GO:0001947 15 12 0,000 0,0926331 0,14081701 ! palate development GO:0060021 15 12 0,000 0,0926331 0,140724 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,0926331 0,14063112 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,0926331 0,14053835 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,0926331 0,14044571 ! arginine metabolic process GO:0006525 13 12 0,000 0,0926331 0,14035319 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,0926331 0,14026079 ! methionine metabolic process GO:0006555 13 12 0,000 0,0926331 0,14016851 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,0926331 0,14007636 ! Golgi organization GO:0007030 18 12 0,000 0,0926331 0,13998432 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,0926331 0,13989241 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,0926331 0,13980062 ! monoamine transport GO:0015844 13 12 0,000 0,0926331 0,13970894 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0926331 0,13961739 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,0926331 0,13952596 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,0926331 0,13943465 ! L-amino acid transport GO:0015807 20 12 0,000 0,0926331 0,13934345 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,0926331 0,13925238 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,0926331 0,13916142 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,0926331 0,13907059 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0926331 0,13897987 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,0926331 0,13888927 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,0926331 0,13879879 ! cerebellum development GO:0021549 13 12 0,000 0,0926331 0,13870842 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,0926331 0,13861818 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,0926331 0,13852805 ! histone methylation GO:0016571 15 12 0,000 0,0926331 0,13843804 ! autonomic nervous system development GO:0048483 23 12 0,000 0,0926331 0,13834814 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,0926331 0,13825836 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,0926331 0,1381687 ! regulation of epidermis development GO:0045682 17 12 0,000 0,0926331 0,13807916 ! intestinal absorption GO:0050892 19 12 0,000 0,0926331 0,13798973 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,0926331 0,13790041 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,0926331 0,13781122 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,0926331 0,13772213 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,0926331 0,13763316 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,0926331 0,13754431 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,0926331 0,13745557 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,0926331 0,13736695 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,0926331 0,13727844 ! response to cold GO:0009409 14 12 0,000 0,0926331 0,13719004 ! appendage morphogenesis GO:0035107 93 64 1,000 0,09426631 0,139519 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 94 65 1,000 0,09676401 0,14312362 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 1,000 0,09676401 0,14303164 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,09676401 0,14293978 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,09676401 0,14284803 ! protein oligomerization GO:0051259 100 65 1,000 0,09676401 0,1427564 ! axon guidance GO:0007411 99 66 1,000 0,0992805 0,14637509 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,09995644 0,14727727 ! cGMP metabolic process GO:0046068 16 13 0,000 0,09995644 0,14718298 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,09995644 0,14708882 ! water transport GO:0006833 17 13 0,000 0,09995644 0,14699477 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,09995644 0,14690084 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,09995644 0,14680704 ! lipid localization GO:0010876 24 13 0,000 0,09995644 0,14671335 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,09995644 0,14661978 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,09995644 0,14652633 ! organelle fusion GO:0048284 28 13 0,000 0,09995644 0,14643301 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,09995644 0,1463398 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,09995644 0,1462467 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,09995644 0,14615373 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,09995644 0,14606088 ! response to hexose stimulus GO:0009746 19 13 0,000 0,09995644 0,14596814 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,09995644 0,14587552 ! glutamate metabolic process GO:0006536 18 13 0,000 0,09995644 0,14578302 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,09995644 0,14569063 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,09995644 0,14559837 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,09995644 0,14550621 ! NAD metabolic process GO:0019674 21 13 0,000 0,09995644 0,14541418 ! bone mineralization GO:0030282 15 13 0,000 0,09995644 0,14532226 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,09995644 0,14523046 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,09995644 0,14513877 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,09995644 0,1450472 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,09995644 0,14495575 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,09995644 0,14486441 ! regulation of cellular pH GO:0030641 20 13 0,000 0,09995644 0,14477319 ! tissue regeneration GO:0042246 21 13 0,000 0,09995644 0,14468208 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,09995644 0,14459108 ! cofactor transport GO:0051181 19 13 0,000 0,09995644 0,1445002 ! NADP metabolic process GO:0006739 18 13 0,000 0,09995644 0,14440943 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,09995644 0,14431878 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,09995644 0,14422824 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,09995644 0,14413782 ! gas transport GO:0015669 18 13 0,000 0,09995644 0,14404751 ! regulation of RNA stability GO:0043487 28 13 0,000 0,09995644 0,14395731 ! heme biosynthetic process GO:0006783 20 13 0,000 0,09995644 0,14386722 ! regulation of axon extension GO:0030516 23 13 0,000 0,09995644 0,14377725 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,09995644 0,14368739 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,09995644 0,14359764 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,09995644 0,143508 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,09995644 0,14341848 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,09995644 0,14332906 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,1018153 0,14590355 ! rhythmic process GO:0048511 105 68 1,000 0,10436798 0,14946846 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,10693807 0,15305386 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,10693807 0,15295868 ! superoxide anion generation GO:0042554 18 14 0,000 0,10722109 0,15326819 ! neuron maturation GO:0042551 21 14 0,000 0,10722109 0,15317299 ! regulation of S phase GO:0033261 18 14 0,000 0,10722109 0,15307791 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,10722109 0,15298295 ! myotube differentiation GO:0014902 21 14 0,000 0,10722109 0,1528881 ! inositol metabolic process GO:0006020 20 14 0,000 0,10722109 0,15279338 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,10722109 0,15269877 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,10722109 0,15260428 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,10722109 0,1525099 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,10722109 0,15241564 ! gene silencing by RNA GO:0031047 20 14 0,000 0,10722109 0,1523215 ! response to cAMP GO:0051591 19 14 0,000 0,10722109 0,15222748 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,10722109 0,15213357 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,10722109 0,15203977 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,10722109 0,15194609 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,10722109 0,15185253 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,10722109 0,15175908 ! pituitary gland development GO:0021983 23 14 0,000 0,10722109 0,15166575 ! cellular response to starvation GO:0009267 21 14 0,000 0,10722109 0,15157253 ! lysosomal transport GO:0007041 20 14 0,000 0,10722109 0,15147943 ! regulation of heart rate GO:0002027 23 14 0,000 0,10722109 0,15138644 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,10722109 0,15129356 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,10722109 0,1512008 ! embryo implantation GO:0007566 27 14 0,000 0,10722109 0,15110816 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,10722109 0,15101562 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,10722109 0,1509232 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,10722109 0,15083089 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,10722109 0,1507387 ! axon cargo transport GO:0008088 27 14 0,000 0,10722109 0,15064662 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,10722109 0,15055465 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,10722109 0,15046279 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,10722109 0,15037104 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,10722109 0,15027941 ! mRNA splice site selection GO:0006376 26 14 0,000 0,10722109 0,15018789 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,10722109 0,15009648 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,10722109 0,15000518 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,10722109 0,14991399 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,10722109 0,14982291 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,10722109 0,14973194 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,10722109 0,14964109 ! muscle maintenance GO:0046716 19 14 0,000 0,10722109 0,14955034 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,10722109 0,1494597 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,10722109 0,14936918 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,10722109 0,14927876 ! cell killing GO:0001906 20 14 0,000 0,10722109 0,14918845 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,10722109 0,14909825 ! cilium assembly GO:0042384 20 14 0,000 0,10722109 0,14900816 ! peptide hormone secretion GO:0030072 23 14 0,000 0,10722109 0,14891818 ! response to metal ion GO:0010038 103 70 1,000 0,10952514 0,15202645 ! humoral immune response GO:0006959 86 70 1,000 0,10952514 0,15193475 ! amine transport GO:0015837 101 70 1,000 0,10952514 0,15184317 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,10952514 0,1517517 ! muscle cell differentiation GO:0042692 104 71 1,000 0,11212875 0,15526558 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,11212875 0,15517216 ! positive regulation of cell size GO:0045793 20 15 0,000 0,11442752 0,15825814 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,11442752 0,15816303 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,11442752 0,15806804 ! skin development GO:0043588 25 15 0,000 0,11442752 0,15797316 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,11442752 0,1578784 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,11442752 0,15778375 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,11442752 0,15768921 ! bile acid metabolic process GO:0008206 22 15 0,000 0,11442752 0,15759478 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,11442752 0,15750047 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,11442752 0,15740627 ! adult walking behavior GO:0007628 25 15 0,000 0,11442752 0,15731219 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,11442752 0,15721821 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,11442752 0,15712435 ! myoblast differentiation GO:0045445 27 15 0,000 0,11442752 0,1570306 ! centrosome cycle GO:0007098 16 15 0,000 0,11442752 0,15693696 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,11442752 0,15684344 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,11442752 0,15675002 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,11442752 0,15665672 ! response to osmotic stress GO:0006970 22 15 0,000 0,11442752 0,15656353 ! vesicle coating GO:0006901 25 15 0,000 0,11442752 0,15647044 ! DNA integration GO:0015074 22 15 0,000 0,11442752 0,15637747 ! peptide secretion GO:0002790 27 15 0,000 0,11442752 0,15628461 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,11442752 0,15619186 ! regulation of vasodilation GO:0042312 24 15 0,000 0,11442752 0,15609922 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,11442752 0,15600669 ! neuron recognition GO:0008038 22 15 0,000 0,11442752 0,15591427 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,11442752 0,15582196 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,11442752 0,15572976 ! biomineral formation GO:0031214 18 15 0,000 0,11442752 0,15563766 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,11442752 0,15554568 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,11442752 0,1554538 ! organic cation transport GO:0015695 19 15 0,000 0,11442752 0,15536203 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,11442752 0,15527038 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,11442752 0,15517882 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,11442752 0,15508738 ! peptide hormone processing GO:0016486 19 15 0,000 0,11442752 0,15499605 ! cellular lipid catabolic process GO:0044242 105 73 1,000 0,11738389 0,15890697 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,11738389 0,1588135 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,12003457 0,16230424 ! protein secretion GO:0009306 27 16 0,000 0,12157618 0,16429214 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,12157618 0,16419566 ! hormone secretion GO:0046879 25 16 0,000 0,12157618 0,1640993 ! bone remodeling GO:0046849 24 16 0,000 0,12157618 0,16400306 ! endothelial cell migration GO:0043542 22 16 0,000 0,12157618 0,16390693 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,12157618 0,16381091 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,12157618 0,163715 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,12157618 0,1636192 ! glial cell development GO:0021782 24 16 0,000 0,12157618 0,16352352 ! patterning of blood vessels GO:0001569 24 16 0,000 0,12157618 0,16342795 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,12157618 0,16333249 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,12157618 0,16323714 ! protein polyubiquitination GO:0000209 26 16 0,000 0,12157618 0,1631419 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,12157618 0,16304677 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,12157618 0,16295176 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,12157618 0,16285685 ! fructose metabolic process GO:0006000 20 16 0,000 0,12157618 0,16276206 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,12157618 0,16266737 ! protein export from nucleus GO:0006611 24 16 0,000 0,12157618 0,1625728 ! negative regulation of immune response GO:0050777 28 16 0,000 0,12157618 0,16247834 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,12157618 0,16238398 ! DNA replication initiation GO:0006270 25 16 0,000 0,12157618 0,16228974 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,12157618 0,1621956 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,12157618 0,16210157 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,12157618 0,16200766 ! diencephalon development GO:0021536 25 16 0,000 0,12157618 0,16191385 ! neural crest cell migration GO:0001755 24 16 0,000 0,12157618 0,16182015 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,12157618 0,16172656 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,12157618 0,16163307 ! steroid catabolic process GO:0006706 22 16 0,000 0,12157618 0,1615397 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,12157618 0,16144643 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,12157618 0,16135327 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,12157618 0,16126022 ! sperm-egg recognition GO:0035036 16 16 0,000 0,12157618 0,16116727 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,12157618 0,16107443 ! nerve development GO:0021675 18 16 0,000 0,12157618 0,1609817 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,12157618 0,16088908 ! negative regulation of translation GO:0017148 22 16 0,000 0,12157618 0,16079656 ! response to inorganic substance GO:0010035 115 75 1,000 0,1227001 0,16218979 ! cofactor biosynthetic process GO:0051188 92 75 1,000 0,1227001 0,16209663 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,12807412 0,16909901 ! protein ubiquitination GO:0016567 125 77 1,000 0,12807412 0,16900199 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,12807412 0,16890508 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,12866754 0,16959046 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,12866754 0,16949333 ! negative regulation of defense response GO:0031348 19 17 0,000 0,12866754 0,16939631 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,12866754 0,1692994 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,12866754 0,1692026 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,12866754 0,16910592 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,12866754 0,16900934 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,12866754 0,16891287 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,12866754 0,16881652 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,12866754 0,16872027 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,12866754 0,16862413 ! keratinization GO:0031424 17 17 0,000 0,12866754 0,1685281 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,12866754 0,16843219 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,12866754 0,16833638 ! retinoid metabolic process GO:0001523 22 17 0,000 0,12866754 0,16824068 GO:0016101|diterpenoid metabolic process, ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,12866754 0,16814509 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,12866754 0,1680496 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,12866754 0,16795423 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,12866754 0,16785896 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,12866754 0,1677638 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,12866754 0,16766875 ! membrane budding GO:0006900 29 17 0,000 0,12866754 0,16757381 ! heme metabolic process GO:0042168 27 17 0,000 0,12866754 0,16747898 ! body fluid secretion GO:0007589 27 17 0,000 0,12866754 0,16738425 ! stem cell differentiation GO:0048863 36 17 0,000 0,12866754 0,16728963 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,12866754 0,16719511 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,12866754 0,16710071 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,12866754 0,16700641 ! sensory perception of pain GO:0019233 23 17 0,000 0,12866754 0,16691221 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,12866754 0,16681812 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,12866754 0,16672414 ! synaptogenesis GO:0007416 24 17 0,000 0,12866754 0,16663027 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,12866754 0,16653649 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,12866754 0,16644283 ! cell-cell junction organization GO:0045216 25 17 0,000 0,12866754 0,16634927 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,12866754 0,16625582 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,1307818 0,16889283 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,1307818 0,16879805 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,13350273 0,17221328 ! T cell activation GO:0042110 134 79 1,000 0,13350273 0,17211675 ! regulation of lyase activity GO:0051339 133 79 1,000 0,13350273 0,17202033 ! positive regulation of translation GO:0045727 28 18 0,000 0,13570206 0,1747563 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,13570206 0,1746585 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,13570206 0,17456082 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,13570206 0,17446325 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,13570206 0,17436578 ! cAMP metabolic process GO:0046058 33 18 0,000 0,13570206 0,17426842 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,13570206 0,17417117 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,13570206 0,17407404 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,13570206 0,173977 ! axis specification GO:0009798 26 18 0,000 0,13570206 0,17388008 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,13570206 0,17378327 GO:0050886|endocrine process, ! pancreas development GO:0031016 26 18 0,000 0,13570206 0,17368656 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,13570206 0,17358996 ! glutamine metabolic process GO:0006541 23 18 0,000 0,13570206 0,17349347 ! response to retinoic acid GO:0032526 25 18 0,000 0,13570206 0,17339708 ! central nervous system neuron development GO:0021954 30 18 0,000 0,13570206 0,1733008 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,13570206 0,17320463 ! fucose metabolic process GO:0006004 26 18 0,000 0,13570206 0,17310857 ! response to fungus GO:0009620 19 18 0,000 0,13570206 0,17301261 ! peptide cross-linking GO:0018149 31 18 0,000 0,13570206 0,17291676 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,13570206 0,17282101 ! heart process GO:0003015 27 18 0,000 0,13570206 0,17272537 GO:0060047|heart contraction, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,13570206 0,17262984 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,13570206 0,17253441 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,13570206 0,17243909 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,13570206 0,17234387 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,13570206 0,17224876 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,13570206 0,17215375 ! vitamin transport GO:0051180 24 18 0,000 0,13570206 0,17205885 ! hormone transport GO:0009914 27 18 0,000 0,13570206 0,17196405 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,13570206 0,17186935 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,13570206 0,17177476 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,13570206 0,17168028 ! cell-cell recognition GO:0009988 20 18 0,000 0,13570206 0,1715859 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,13570206 0,17149162 ! chromatin assembly GO:0031497 102 80 1,000 0,13623654 0,17207252 GO:0006334|nucleosome assembly, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,13623654 0,17197807 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 1,000 0,13623654 0,17188374 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,13898285 0,17525249 ! response to protein stimulus GO:0051789 111 81 1,000 0,13898285 0,17515646 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,13898285 0,17506054 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,14174127 0,17843728 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,14174127 0,17833967 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,14268019 0,17942287 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,14268019 0,17932483 ! positive regulation of ossification GO:0045778 30 19 0,000 0,14268019 0,17922689 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,14268019 0,17912906 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,14268019 0,17903134 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,14268019 0,17893372 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,14268019 0,17883621 ! sensory perception of taste GO:0050909 23 19 0,000 0,14268019 0,1787388 ! smooth muscle contraction GO:0006939 36 19 0,000 0,14268019 0,1786415 ! peroxisome organization GO:0007031 29 19 0,000 0,14268019 0,17854431 ! digestive system process GO:0022600 30 19 0,000 0,14268019 0,17844722 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,14268019 0,17835024 ! response to vitamin A GO:0033189 26 19 0,000 0,14268019 0,17825336 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,14268019 0,17815659 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,14268019 0,17805992 ! response to starvation GO:0042594 30 19 0,000 0,14268019 0,17796336 ! sex determination GO:0007530 29 19 0,000 0,14268019 0,1778669 ! plasma membrane fusion GO:0045026 23 19 0,000 0,14268019 0,17777055 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,14268019 0,1776743 ! cytolysis GO:0019835 20 19 0,000 0,14268019 0,17757816 ! vasodilation GO:0042311 33 19 0,000 0,14268019 0,17748212 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,14268019 0,17738618 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,14268019 0,17729035 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,14268019 0,17719462 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,14268019 0,17709899 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,14268019 0,17700347 ! sarcomere organization GO:0045214 23 19 0,000 0,14268019 0,17690805 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,14268019 0,17681274 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,14268019 0,17671752 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,14268019 0,17662241 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,14268019 0,1765274 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,14268019 0,17643249 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,14451143 0,17860091 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 107 84 1,000 0,14729298 0,18194085 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,14960237 0,18469429 ! iron ion transport GO:0006826 37 20 0,000 0,14960237 0,1845952 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,14960237 0,18449623 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,14960237 0,18439735 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,14960237 0,18429859 ! response to vitamin GO:0033273 29 20 0,000 0,14960237 0,18419992 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,14960237 0,18410137 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,14960237 0,18400292 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,14960237 0,18390458 ! spinal cord development GO:0021510 31 20 0,000 0,14960237 0,18380634 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,14960237 0,1837082 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,14960237 0,18361017 ! chromosome condensation GO:0030261 31 20 0,000 0,14960237 0,18351225 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,14960237 0,18341442 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,14960237 0,18331671 ! collagen fibril organization GO:0030199 45 20 0,000 0,14960237 0,18321909 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,14960237 0,18312159 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,14960237 0,18302418 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,14960237 0,18292688 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,14960237 0,18282968 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,14960237 0,18273259 ! actin filament-based movement GO:0030048 34 20 0,000 0,14960237 0,18263559 ! rRNA metabolic process GO:0016072 107 85 1,000 0,15008555 0,18312826 GO:0006364|rRNA processing, ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,15288879 0,18644974 ! nucleosome organization GO:0034728 114 87 1,000 0,15570234 0,18978028 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,15570234 0,18967976 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,15646906 0,19051288 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,15646906 0,19041208 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,15646906 0,19031139 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,15646906 0,1902108 GO:0009799|determination of symmetry, ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,15646906 0,19011032 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,15646906 0,19000995 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,15646906 0,18990968 ! vesicle docking GO:0048278 27 21 0,000 0,15646906 0,18980951 ! phototransduction GO:0007602 25 21 0,000 0,15646906 0,18970946 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,15646906 0,1896095 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,15646906 0,18950966 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,15646906 0,18940991 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,15646906 0,18931028 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,15646906 0,18921074 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,15646906 0,18911132 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,15646906 0,18901199 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,15646906 0,18891278 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,15646906 0,18881366 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,15646906 0,18871465 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,15646906 0,18861574 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,15646906 0,18851694 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,15646906 0,18841824 ! immunoglobulin production GO:0002377 33 21 0,000 0,15646906 0,18831964 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,15646906 0,18822115 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,15646906 0,18812276 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,15646906 0,18802447 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,15646906 0,18792629 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,15646906 0,1878282 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,15646906 0,18773022 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,15646906 0,18763234 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,15646906 0,18753457 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,15646906 0,18743689 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,15646906 0,18733932 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,15646906 0,18724185 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,15646906 0,18714448 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,15852587 0,18950598 ! protein processing GO:0016485 114 88 1,000 0,15852587 0,18940753 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,16135903 0,1926925 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,16135903 0,19259251 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,16328069 0,19478505 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,16328069 0,19468408 ! viral genome replication GO:0019079 29 22 0,000 0,16328069 0,1945832 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,16328069 0,19448244 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,16328069 0,19438177 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,16328069 0,19428121 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,16328069 0,19418076 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,16328069 0,19408041 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,16328069 0,19398016 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,16328069 0,19388001 ! lysosome organization GO:0007040 37 22 0,000 0,16328069 0,19377997 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,16328069 0,19368003 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,16328069 0,1935802 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,16328069 0,19348047 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,16328069 0,19338084 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,16328069 0,19328131 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,16328069 0,19318189 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,16328069 0,19308256 ! neural tube closure GO:0001843 33 22 0,000 0,16328069 0,19298334 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,16328069 0,19288422 ! protein tetramerization GO:0051262 39 22 0,000 0,16328069 0,19278521 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,16420148 0,19377291 ! hormone metabolic process GO:0042445 121 90 1,000 0,16420148 0,19367354 ! response to virus GO:0009615 122 91 1,000 0,1670529 0,19693576 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,16991295 0,20020481 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,16991295 0,2001023 ! DNA recombination GO:0006310 146 92 1,000 0,16991295 0,1999999 ! sulfur metabolic process GO:0006790 118 92 1,000 0,16991295 0,19989759 ! neuron fate commitment GO:0048663 32 23 0,000 0,1700377 0,19994208 ! embryonic pattern specification GO:0009880 31 23 0,000 0,1700377 0,19983991 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,1700377 0,19973785 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,1700377 0,19963589 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,1700377 0,19953404 ! vesicle targeting GO:0006903 32 23 0,000 0,1700377 0,19943229 ! osteoblast differentiation GO:0001649 40 23 0,000 0,1700377 0,19933064 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,1700377 0,19922909 ! interaction with host GO:0051701 37 23 0,000 0,1700377 0,19912765 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,1700377 0,19902632 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,1700377 0,19892508 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,1700377 0,19882395 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,1700377 0,19872292 ! cell fate determination GO:0001709 45 23 0,000 0,1700377 0,198622 ! pentose metabolic process GO:0019321 31 23 0,000 0,1700377 0,19852117 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,1700377 0,19842045 ! spermatid development GO:0007286 33 23 0,000 0,1700377 0,19831983 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,1700377 0,19821932 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,1700377 0,1981189 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,1700377 0,19801859 ! telomere organization GO:0032200 32 23 0,000 0,1700377 0,19791838 GO:0000723|telomere maintenance, ! regulation of amine transport GO:0051952 38 23 0,000 0,1700377 0,19781827 ! liver development GO:0001889 40 23 0,000 0,1700377 0,19771826 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,17278133 0,200807 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,17278133 0,20070558 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,17674053 0,20520102 ! initiation of viral infection GO:0019059 42 24 0,000 0,17674053 0,20509749 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,17674053 0,20499406 ! superoxide metabolic process GO:0006801 32 24 0,000 0,17674053 0,20489073 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,17674053 0,20478751 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,17674053 0,2046844 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,17674053 0,20458139 ! sperm motility GO:0030317 27 24 0,000 0,17674053 0,20447848 ! vacuole organization GO:0007033 39 24 0,000 0,17674053 0,20437567 ! neural crest cell development GO:0014032 39 24 0,000 0,17674053 0,20427297 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,17674053 0,20417038 ! negative regulation of cell development GO:0010721 56 24 0,000 0,17674053 0,20406788 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,17674053 0,20396549 ! base-excision repair GO:0006284 31 24 0,000 0,17674053 0,2038632 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,17674053 0,20376101 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,17674053 0,20365893 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,17674053 0,20355694 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,17674053 0,20345506 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,17674053 0,20335329 ! in utero embryonic development GO:0001701 147 96 1,000 0,18143321 0,20864819 ! protein maturation GO:0051604 129 96 1,000 0,18143321 0,20854392 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,18338961 0,21068736 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,18338961 0,21058217 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,18338961 0,21047709 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,18338961 0,21037212 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,18338961 0,21026725 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,18338961 0,21016248 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,18338961 0,21005782 ! peptide transport GO:0015833 43 25 0,000 0,18338961 0,20995326 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,18338961 0,2098488 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,18338961 0,20974445 ! phospholipid transport GO:0015914 35 25 0,000 0,18338961 0,20964021 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,18338961 0,20953606 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,18338961 0,20943202 ! detection of light stimulus GO:0009583 30 25 0,000 0,18338961 0,20932809 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,18998536 0,21674917 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,18998536 0,21664171 ! translational initiation GO:0006413 43 26 0,000 0,18998536 0,21653435 ! regulation of pH GO:0006885 36 26 0,000 0,18998536 0,21642711 ! circadian rhythm GO:0007623 42 26 0,000 0,18998536 0,21631996 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,18998536 0,21621293 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,18998536 0,216106 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,18998536 0,21599917 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,18998536 0,21589245 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,18998536 0,21578584 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,18998536 0,21567933 ! calcium ion transport GO:0006816 167 99 1,000 0,1901488 0,21575838 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 1,000 0,19306676 0,21896132 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,19306676 0,2188534 ! divalent metal ion transport GO:0070838 171 100 1,000 0,19306676 0,21874559 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,19652821 0,2225578 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,19652821 0,22244827 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,19652821 0,22233885 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,19652821 0,22222954 ! membrane docking GO:0022406 39 27 0,000 0,19652821 0,22212034 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,19652821 0,22201124 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,19652821 0,22190225 ! acute-phase response GO:0006953 42 27 0,000 0,19652821 0,22179337 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,19652821 0,2216846 ! myofibril assembly GO:0030239 36 27 0,000 0,19652821 0,22157593 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,19652821 0,22146736 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,19652821 0,22135891 ! natural killer cell activation GO:0030101 35 27 0,000 0,19652821 0,22125056 ! cofactor catabolic process GO:0051187 45 27 0,000 0,19652821 0,22114231 ! gene silencing GO:0016458 41 27 0,000 0,19652821 0,22103418 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,20301859 0,22822227 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,20301859 0,22811078 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,20301859 0,22799939 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,20301859 0,22788812 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,20301859 0,22777695 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,20301859 0,2276659 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,20301859 0,22755495 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,20301859 0,22744411 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,20301859 0,22733338 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,20301859 0,22722275 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,20301859 0,22711224 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,20301859 0,22700183 ! mesoderm formation GO:0001707 46 28 0,000 0,20301859 0,22689152 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,20301859 0,22678133 ! BMP signaling pathway GO:0030509 40 28 0,000 0,20301859 0,22667124 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,20301859 0,22656126 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,20301859 0,22645139 ! neural tube formation GO:0001841 41 28 0,000 0,20301859 0,22634162 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,20301859 0,22623196 ! regulation of innate immune response GO:0045088 38 29 0,000 0,20945691 0,23329341 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,20945691 0,23318049 ! protein targeting to membrane GO:0006612 53 29 0,000 0,20945691 0,23306768 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,20945691 0,23295497 ! mismatch repair GO:0006298 34 29 0,000 0,20945691 0,23284238 ! muscle cell development GO:0055001 38 29 0,000 0,20945691 0,2327299 ! formation of primary germ layer GO:0001704 48 29 0,000 0,20945691 0,23261752 ! eye morphogenesis GO:0048592 51 29 0,000 0,20945691 0,23250525 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,20945691 0,23239309 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,21584358 0,23936366 ! organic anion transport GO:0015711 51 30 0,000 0,21584358 0,2392483 ! cholesterol transport GO:0030301 46 30 0,000 0,21584358 0,23913306 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,21584358 0,23901792 ! spliceosome assembly GO:0000245 49 30 0,000 0,21584358 0,2389029 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,21584358 0,23878799 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,21584358 0,23867319 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,21584358 0,2385585 ! ceramide metabolic process GO:0006672 43 30 0,000 0,21584358 0,23844391 ! adult locomotory behavior GO:0008344 47 30 0,000 0,21584358 0,23832944 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,21584358 0,23821508 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,21584358 0,23810083 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,21584358 0,23798669 ! negative regulation of secretion GO:0051048 49 31 0,000 0,22217902 0,24485469 ! glial cell differentiation GO:0010001 55 31 0,000 0,22217902 0,24473742 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,22217902 0,24462027 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,22217902 0,24450322 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,22217902 0,24438629 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,22217902 0,24426947 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,22217902 0,24415276 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,22217902 0,24403617 ! RNA modification GO:0009451 40 31 0,000 0,22217902 0,24391968 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,22846363 0,25069959 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,22846363 0,25058004 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,22846363 0,2504606 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,22846363 0,25034128 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,22846363 0,25022207 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,22846363 0,25010297 ! cytokine production GO:0001816 44 32 0,000 0,22846363 0,24998399 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,22846363 0,24986512 ! vesicle localization GO:0051648 47 32 0,000 0,22846363 0,24974636 ! RNA export from nucleus GO:0006405 44 33 0,000 0,23469782 0,25643942 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,23469782 0,25631766 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,23469782 0,256196 ! actomyosin structure organization GO:0031032 43 33 0,000 0,23469782 0,25607447 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,23469782 0,25595305 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,23469782 0,25583175 ! regulation of proteolysis GO:0030162 50 33 0,000 0,23469782 0,25571056 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,23469782 0,25558948 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,23469782 0,25546852 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,23469782 0,25534767 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,24088199 0,26195205 ! mRNA catabolic process GO:0006402 48 34 0,000 0,24088199 0,26182825 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,24088199 0,26170457 ! feeding behavior GO:0007631 45 34 0,000 0,24088199 0,26158101 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,24088199 0,26145756 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,24088199 0,26133423 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,24088199 0,26121102 ! aerobic respiration GO:0009060 47 34 0,000 0,24088199 0,26108792 ! embryonic organ development GO:0048568 45 34 0,000 0,24088199 0,26096494 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,24088199 0,26084208 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,24701654 0,26735908 ! Notch signaling pathway GO:0007219 56 35 0,000 0,24701654 0,26723332 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,24701654 0,26710768 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,24701654 0,26698216 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,24701654 0,26685676 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,24701654 0,26673148 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,24701654 0,26660631 GO:0015986|ATP synthesis coupled proton transport, ! regulation of hormone secretion GO:0046883 48 36 0,000 0,25310187 0,2730461 ! organic ether metabolic process GO:0018904 46 36 0,000 0,25310187 0,27291809 ! tissue remodeling GO:0048771 62 36 0,000 0,25310187 0,2727902 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,25310187 0,27266243 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,25310187 0,27253478 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,25913836 0,27890417 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,25913836 0,27877372 ! ion transmembrane transport GO:0034220 56 37 0,000 0,25913836 0,2786434 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,25913836 0,27851319 ! regulation of protein secretion GO:0050708 51 37 0,000 0,25913836 0,2783831 ! amino acid activation GO:0043038 52 37 0,000 0,25913836 0,27825314 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,25913836 0,2781233 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,26512641 0,28441732 ! gliogenesis GO:0042063 71 38 0,000 0,26512641 0,28428472 ! phagocytosis GO:0006909 60 38 0,000 0,26512641 0,28415225 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,27106639 0,29038319 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,27106639 0,290248 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,27106639 0,29011294 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,27106639 0,289978 ! chromatin remodeling GO:0006338 68 39 0,000 0,27106639 0,28984319 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,27106639 0,28970851 ! JNK cascade GO:0007254 54 39 0,000 0,27106639 0,28957395 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,27695871 0,29573121 ! response to calcium ion GO:0051592 58 40 0,000 0,27695871 0,29559398 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,27695871 0,29545688 ! regulation of tube size GO:0035150 60 40 0,000 0,27695871 0,2953199 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,27695871 0,29518305 ! peptide metabolic process GO:0006518 56 40 0,000 0,27695871 0,29504633 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,27695871 0,29490974 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,27695871 0,29477327 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,28280373 0,30085503 ! striated muscle contraction GO:0006941 62 41 0,000 0,28280373 0,30071594 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,28280373 0,30057698 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,28280373 0,30043814 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,28860183 0,30645624 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,28860183 0,30631482 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,28860183 0,30617353 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,28860183 0,30603237 ! excretion GO:0007588 63 42 0,000 0,28860183 0,30589134 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,28860183 0,30575044 ! regulation of cell shape GO:0008360 78 42 0,000 0,28860183 0,30560967 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,29435338 0,31155674 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,29435338 0,31141342 ! tRNA processing GO:0008033 49 43 0,000 0,29435338 0,31127025 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,29435338 0,3111272 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,30005877 0,31701202 ! glycolysis GO:0006096 53 44 0,000 0,30005877 0,31686647 ! regulation of ion transport GO:0043269 57 44 0,000 0,30005877 0,31672105 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,30005877 0,31657576 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,30005877 0,31643061 ! RNA catabolic process GO:0006401 64 45 0,000 0,30571835 0,32225123 ! regulation of translational initiation GO:0006446 64 45 0,000 0,30571835 0,32210362 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,30571835 0,32195613 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,30571835 0,32180878 ! cell recognition GO:0008037 58 45 0,000 0,30571835 0,32166157 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,31133248 0,32741871 ! cell redox homeostasis GO:0045454 63 46 0,000 0,31133248 0,32726906 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,31133248 0,32711956 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,31690154 0,33281897 ! viral infectious cycle GO:0019058 71 47 0,000 0,31690154 0,33266707 ! endocrine system development GO:0035270 83 47 0,000 0,31690154 0,3325153 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,31690154 0,33236368 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,31690154 0,33221219 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,31690154 0,33206084 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,31690154 0,33190963 ! chloride transport GO:0006821 67 48 0,000 0,32242588 0,33754189 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,32242588 0,33738832 ! gastrulation GO:0007369 73 48 0,000 0,32242588 0,33723489 ! heart morphogenesis GO:0003007 65 48 0,000 0,32242588 0,3370816 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,32242588 0,33692846 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,32242588 0,33677545 ! regulation of endocytosis GO:0030100 63 48 0,000 0,32242588 0,33662257 ! nuclear export GO:0051168 69 48 0,000 0,32242588 0,33646984 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,32242588 0,33631725 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,32790586 0,34187828 ! sensory perception of smell GO:0007608 61 49 0,000 0,32790586 0,34172337 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,32790586 0,34156861 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,32790586 0,34141398 ! RNA elongation GO:0006354 62 49 0,000 0,32790586 0,34125949 ! regulation of actin filament length GO:0030832 72 50 0,000 0,33334183 0,34675993 ! proton transport GO:0015992 75 50 0,000 0,33334183 0,34660317 ! positive regulation of secretion GO:0051047 71 51 0,000 0,33873415 0,35205085 ! hydrogen transport GO:0006818 77 51 0,000 0,33873415 0,35189184 ! adult behavior GO:0030534 80 51 0,000 0,33873415 0,35173297 ! transition metal ion transport GO:0000041 74 52 0,000 0,34408315 0,35712601 ! regulation of cellular component size GO:0032535 74 52 0,000 0,34408315 0,35696493 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,34408315 0,35680399 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,34408315 0,35664319 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,34938919 0,36197979 ! single fertilization GO:0007338 59 53 0,000 0,34938919 0,36181681 ! glucose catabolic process GO:0006007 66 54 0,000 0,35465261 0,36710216 ! exocytosis GO:0006887 74 55 0,000 0,35987375 0,37233901 ! mesoderm development GO:0007498 76 55 0,000 0,35987375 0,37217159 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,35987375 0,37200432 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,35987375 0,3718372 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,37019052 0,38232519 ! camera-type eye development GO:0043010 88 57 0,000 0,37019052 0,38215359 ! viral reproductive process GO:0022415 87 58 0,000 0,37528683 0,38724078 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,37528683 0,38706713 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,37528683 0,38689364 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,38034219 0,39192967 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,38535692 0,39691936 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,38535692 0,39674168 ! fertilization GO:0009566 68 60 0,000 0,38535692 0,39656417 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,39033136 0,40150364 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,39033136 0,40132415 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,39033136 0,40114483 ! neurotransmitter transport GO:0006836 81 62 0,000 0,39526582 0,40603457 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,39526582 0,4058533 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,39526582 0,4056722 ! viral reproduction GO:0016032 92 63 0,000 0,40016063 0,41051269 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,4050161 0,41530852 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,4050161 0,41512345 ! hexose catabolic process GO:0019320 82 64 0,000 0,4050161 0,41493854 ! adaptive immune response GO:0002250 94 64 0,000 0,4050161 0,41475379 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! defense response to bacterium GO:0042742 73 65 0,000 0,40983253 0,41949926 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,40983253 0,41931265 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,40983253 0,4191262 ! activation of immune response GO:0002253 83 65 0,000 0,40983253 0,41893992 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,41461026 0,42363554 ! antigen processing and presentation GO:0019882 96 66 0,000 0,41461026 0,42344742 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,41461026 0,42325947 ! regulation of immune effector process GO:0002697 101 66 0,000 0,41461026 0,42307169 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,41934958 0,42771797 ! acute inflammatory response GO:0002526 92 68 0,000 0,42405079 0,43232129 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,42405079 0,43212974 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,42405079 0,43193836 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,42405079 0,43174716 ! inorganic anion transport GO:0015698 93 68 0,000 0,42405079 0,43155612 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,42871422 0,43610911 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,43334014 0,44061995 ! eye development GO:0001654 111 70 0,000 0,43334014 0,44042525 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,43792888 0,44489241 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,43792888 0,44469599 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,43792888 0,44449974 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,45147487 0,45804685 ! digestion GO:0007586 97 74 0,000 0,45147487 0,45784489 ! protein import into nucleus GO:0006606 118 74 0,000 0,45147487 0,45764311 ! nuclear import GO:0051170 121 75 0,000 0,45591777 0,46194312 ! tRNA metabolic process GO:0006399 95 76 0,000 0,46032494 0,46620316 ! response to unfolded protein GO:0006986 99 76 0,000 0,46032494 0,46599796 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,46032494 0,46579295 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,46469667 0,47000982 ! cellular respiration GO:0045333 107 79 0,000 0,47333489 0,47853638 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,47333489 0,47832612 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,47333489 0,47811606 ! alcohol catabolic process GO:0046164 104 80 0,000 0,47760196 0,48221445 ! protein localization in nucleus GO:0034504 133 80 0,000 0,47760196 0,48200286 ! mRNA transport GO:0051028 121 81 0,000 0,4818347 0,48606132 ! vitamin metabolic process GO:0006766 103 81 0,000 0,4818347 0,48584823 ! sterol metabolic process GO:0016125 120 84 0,000 0,49432968 0,49822886 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,49842782 0,50213929 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,50652544 0,51007378 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,50652544 0,50985055 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,51052543 0,51365201 ! establishment of RNA localization GO:0051236 128 88 0,000 0,51052543 0,51342741 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,51449323 0,51719162 ! RNA localization GO:0006403 135 91 0,000 0,52233327 0,52484339 ! ATP metabolic process GO:0046034 137 91 0,000 0,52233327 0,5246142 ! positive regulation of immune response GO:0050778 121 92 0,000 0,52620602 0,52827318 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,5300476 0,53189768 ! electron transport chain GO:0022900 123 94 0,000 0,53385824 0,53548799 ! angiogenesis GO:0001525 149 95 0,000 0,5376382 0,53904441 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,54138773 0,54256722 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,54510706 0,54605673 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! protein import GO:0017038 156 99 0,000 0,55245611 0,55317765 ! regulation of translation GO:0006417 151 100 0,000 0,55608631 0,55657028 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,55608631 0,55632819 ! protein localization in organelle GO:0033365 161 100 0,000 0,55608631 0,55608631