pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6610-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G2/M transition of mitotic cell cycle GO:0000086 43 25 6,000 1,39E-10 3,345E-07 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 6,000 1,892E-10 2,277E-07 GO:0045936|negative regulation of phosphate metabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 9,000 4,28E-10 3,433E-07 ! interphase GO:0051325 213 98 9,000 5,838E-10 3,511E-07 ! S phase GO:0051320 9 9 4,000 1,08E-09 5,198E-07 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of phosphorylation GO:0042326 47 24 5,000 6,485E-09 2,6E-06 ! glycine biosynthetic process GO:0006545 7 5 3,000 7,162E-09 2,462E-06 ! regulation of lipid kinase activity GO:0043550 13 7 3,000 4,965E-08 1,493E-05 ! mitotic sister chromatid segregation GO:0000070 57 36 5,000 8,821E-08 2,358E-05 ! sister chromatid segregation GO:0000819 58 37 5,000 1,047E-07 2,52E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 2,019E-07 4,415E-05 ! negative regulation of kinase activity GO:0033673 131 68 6,000 2,239E-07 4,488E-05 ! negative regulation of transferase activity GO:0051348 140 72 6,000 3,331E-07 6,166E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 4,202E-07 7,221E-05 ! negative regulation of protein modification process GO:0031400 60 28 4,000 7,655E-07 1,228E-04 ! serine family amino acid biosynthetic process GO:0009070 17 13 3,000 9,85E-07 1,481E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 3,000 1,372E-06 1,942E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 2,334E-06 3,12E-04 ! glycine metabolic process GO:0006544 28 17 3,000 3,216E-06 4,072E-04 ! chromosome segregation GO:0007059 113 67 5,000 3,853E-06 4,635E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 3,853E-06 4,415E-04 ! cell-substrate junction assembly GO:0007044 54 18 3,000 4,114E-06 4,5E-04 ! nuclear migration GO:0007097 12 6 2,000 4,647E-06 4,861E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 4,647E-06 4,659E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 5,000 5,879E-06 5,658E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 6,451E-06 5,97E-04 ! positive regulation of protein ubiquitination GO:0031398 12 7 2,000 8,095E-06 7,214E-04 ! macrophage differentiation GO:0030225 11 7 2,000 8,095E-06 6,956E-04 ! fibrinolysis GO:0042730 10 7 2,000 8,095E-06 6,716E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 8,095E-06 6,492E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 8,737E-06 6,781E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 9,753E-06 7,333E-04 ! pigmentation GO:0043473 100 46 4,000 9,753E-06 7,111E-04 ! positive regulation of phosphorylation GO:0042327 129 79 5,000 1,009E-05 7,141E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 3,000 1,162E-05 7,988E-04 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 5,000 1,166E-05 7,793E-04 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,289E-05 8,384E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,289E-05 8,163E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,289E-05 7,954E-04 ! positive regulation of protein modification process GO:0031401 136 88 5,000 1,878E-05 1,13E-03 ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,925E-05 1,13E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,925E-05 1,103E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 1,934E-05 1,082E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 2,622E-05 1,434E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,738E-05 1,464E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,738E-05 1,432E-03 ! cell junction assembly GO:0034329 78 30 3,000 3,476E-05 1,78E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 3,747E-05 1,878E-03 ! nitric oxide metabolic process GO:0046209 15 11 2,000 3,747E-05 1,84E-03 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of glucose import GO:0046325 17 11 2,000 3,747E-05 1,803E-03 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 19 11 2,000 3,747E-05 1,768E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 3,926E-05 1,816E-03 ! serine family amino acid metabolic process GO:0009069 49 31 3,000 3,972E-05 1,803E-03 ! ear development GO:0043583 103 62 4,000 4,249E-05 1,893E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 4,973E-05 2,175E-03 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 4,973E-05 2,137E-03 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 30 12 2,000 4,973E-05 2,099E-03 ! focal adhesion formation GO:0048041 35 12 2,000 4,973E-05 2,063E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 4,973E-05 2,028E-03 GO:0042130|negative regulation of T cell proliferation, ! myeloid cell differentiation GO:0030099 111 65 4,000 5,342E-05 2,142E-03 ! negative regulation of cell growth GO:0030308 132 67 4,000 6,184E-05 2,439E-03 ! lung development GO:0030324 144 67 4,000 6,184E-05 2,4E-03 ! regulation of skeletal muscle fiber development GO:0048742 32 13 2,000 6,435E-05 2,458E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 7,125E-05 2,678E-03 ! cell junction organization GO:0034330 86 36 3,000 7,258E-05 2,686E-03 ! respiratory tube development GO:0030323 150 70 4,000 7,634E-05 2,783E-03 ! regulation of protein stability GO:0031647 73 37 3,000 8,098E-05 2,908E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 8,098E-05 2,865E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 8,153E-05 2,843E-03 ! respiratory system development GO:0060541 153 72 4,000 8,738E-05 3,003E-03 ! regulation of skeletal muscle tissue development GO:0048641 35 15 2,000 1,014E-04 3,438E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,014E-04 3,39E-03 ! dopamine metabolic process GO:0042417 35 15 2,000 1,014E-04 3,344E-03 ! regulation of protein ubiquitination GO:0031396 25 16 2,000 1,243E-04 4,041E-03 ! filopodium assembly GO:0046847 32 16 2,000 1,243E-04 3,987E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,243E-04 3,935E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! epithelial cell differentiation GO:0030855 79 43 3,000 1,47E-04 4,593E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,47E-04 4,534E-03 ! negative regulation of protein catabolic process GO:0042177 40 17 2,000 1,502E-04 4,575E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,502E-04 4,518E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,502E-04 4,463E-03 ! negative regulation of blood coagulation GO:0030195 24 17 2,000 1,502E-04 4,408E-03 ! microspike assembly GO:0030035 36 17 2,000 1,502E-04 4,355E-03 ! JAK-STAT cascade GO:0007259 71 44 3,000 1,609E-04 4,609E-03 ! response to drug GO:0042493 143 82 4,000 1,621E-04 4,588E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,621E-04 4,534E-03 ! cell growth GO:0016049 84 45 3,000 1,757E-04 4,86E-03 ! memory GO:0007613 31 18 2,000 1,795E-04 4,907E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,795E-04 4,851E-03 ! negative regulation of growth GO:0045926 155 84 4,000 1,816E-04 4,854E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 1,916E-04 5,065E-03 ! one-carbon metabolic process GO:0006730 154 85 4,000 1,919E-04 5,02E-03 ! amine biosynthetic process GO:0009309 138 86 4,000 2,028E-04 5,246E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 2,121E-04 5,43E-03 ! G1 phase GO:0051318 40 19 2,000 2,121E-04 5,373E-03 ! estrogen receptor signaling pathway GO:0030520 38 19 2,000 2,121E-04 5,317E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 2,262E-04 5,611E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 3,000 2,451E-04 6,018E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,484E-04 6,038E-03 ! response to alkaloid GO:0043279 38 20 2,000 2,484E-04 5,977E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,484E-04 5,918E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,484E-04 5,86E-03 GO:0010827|regulation of glucose transport, ! inner ear receptor cell differentiation GO:0060113 37 20 2,000 2,484E-04 5,803E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,484E-04 5,747E-03 ! negative regulation of coagulation GO:0050819 29 20 2,000 2,484E-04 5,693E-03 ! regulation of cell cycle process GO:0010564 149 90 4,000 2,508E-04 5,693E-03 ! cellular amino acid biosynthetic process GO:0008652 75 51 3,000 2,863E-04 6,439E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 3,000 2,863E-04 6,379E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,863E-04 6,321E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,885E-04 6,311E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,885E-04 6,254E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 2,885E-04 6,198E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,885E-04 6,143E-03 ! response to cytokine stimulus GO:0034097 63 21 2,000 2,885E-04 6,089E-03 ! forebrain development GO:0030900 188 95 4,000 3,225E-04 6,748E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 3,325E-04 6,897E-03 ! glutamate signaling pathway GO:0007215 41 22 2,000 3,325E-04 6,839E-03 ! mechanoreceptor differentiation GO:0042490 40 22 2,000 3,325E-04 6,781E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 3,325E-04 6,724E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 3,325E-04 6,668E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 3,325E-04 6,612E-03 ! leukocyte differentiation GO:0002521 202 96 4,000 3,386E-04 6,677E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 3,552E-04 6,948E-03 ! positive regulation of helicase activity GO:0051096 11 5 1,000 3,788E-04 7,35E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 3,788E-04 7,291E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 3,788E-04 7,233E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,788E-04 7,176E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 3,788E-04 7,12E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 3,788E-04 7,065E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,788E-04 7,011E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,788E-04 6,957E-03 ! valine metabolic process GO:0006573 10 5 1,000 3,788E-04 6,904E-03 ! muscle cell migration GO:0014812 8 5 1,000 3,788E-04 6,852E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,788E-04 6,801E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,788E-04 6,751E-03 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 1,000 3,788E-04 6,701E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 3,788E-04 6,652E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,788E-04 6,604E-03 ! decidualization GO:0046697 11 5 1,000 3,788E-04 6,557E-03 ! neural tube patterning GO:0021532 7 5 1,000 3,788E-04 6,51E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,788E-04 6,464E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 3,788E-04 6,418E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 3,788E-04 6,373E-03 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 3,788E-04 6,329E-03 ! receptor biosynthetic process GO:0032800 7 5 1,000 3,788E-04 6,285E-03 ! stem cell division GO:0017145 11 5 1,000 3,788E-04 6,242E-03 GO:0048103|somatic stem cell division, ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 3,807E-04 6,231E-03 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 2,000 3,807E-04 6,189E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 3,807E-04 6,147E-03 ! negative regulation of catabolic process GO:0009895 50 23 2,000 3,807E-04 6,106E-03 ! cell cycle arrest GO:0007050 213 100 4,000 4,088E-04 6,513E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 4,331E-04 6,855E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 4,331E-04 6,81E-03 ! multicellular organismal response to stress GO:0033555 49 24 2,000 4,331E-04 6,766E-03 ! regulation of behavior GO:0050795 43 24 2,000 4,331E-04 6,723E-03 ! receptor metabolic process GO:0043112 46 25 2,000 4,899E-04 7,556E-03 ! regulation of blood coagulation GO:0030193 40 25 2,000 4,899E-04 7,508E-03 ! establishment of organelle localization GO:0051656 109 59 3,000 5,017E-04 7,64E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 5,35E-04 8,095E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 5,513E-04 8,29E-03 ! sleep GO:0030431 13 6 1,000 5,659E-04 8,456E-03 ! response to interferon-gamma GO:0034341 15 6 1,000 5,659E-04 8,404E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 5,659E-04 8,353E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 5,659E-04 8,302E-03 GO:0051653|spindle localization, ! monocyte differentiation GO:0030224 12 6 1,000 5,659E-04 8,251E-03 ! neural nucleus development GO:0048857 14 6 1,000 5,659E-04 8,202E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 5,659E-04 8,153E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 5,659E-04 8,104E-03 ! protein deubiquitination GO:0016579 14 6 1,000 5,659E-04 8,056E-03 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 1,000 5,659E-04 8,009E-03 ! maternal placenta development GO:0001893 12 6 1,000 5,659E-04 7,962E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 5,659E-04 7,916E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 6,174E-04 8,586E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 6,174E-04 8,537E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 6,174E-04 8,488E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 6,174E-04 8,44E-03 ! regulation of mitosis GO:0007088 105 63 3,000 6,441E-04 8,756E-03 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 3,000 6,441E-04 8,706E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 6,441E-04 8,658E-03 ! dendrite development GO:0016358 59 28 2,000 6,883E-04 9,2E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 7,642E-04 0,01015875 ! catechol metabolic process GO:0009712 54 29 2,000 7,642E-04 0,01010293 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of coagulation GO:0050818 46 29 2,000 7,642E-04 0,01004772 ! actin filament organization GO:0007015 148 66 3,000 7,682E-04 0,01004447 ! regulation of helicase activity GO:0051095 15 7 1,000 7,89E-04 0,01026092 ! prostate gland development GO:0030850 13 7 1,000 7,89E-04 0,01020575 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 7,89E-04 0,01015117 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 7,89E-04 0,01009718 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 7,89E-04 0,01004375 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,89E-04 9,991E-03 ! lipoprotein transport GO:0042953 14 7 1,000 7,89E-04 9,939E-03 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 1,000 7,89E-04 9,887E-03 ! organ growth GO:0035265 15 7 1,000 7,89E-04 9,836E-03 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 7,89E-04 9,785E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 7,89E-04 9,735E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 7,89E-04 9,685E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 7,89E-04 9,636E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 7,89E-04 9,587E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 7,89E-04 9,539E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 7,89E-04 9,491E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 7,89E-04 9,444E-03 ! protein modification by small protein removal GO:0070646 16 7 1,000 7,89E-04 9,397E-03 ! phenol metabolic process GO:0018958 55 30 2,000 8,453E-04 0,01001844 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 8,453E-04 9,969E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 8,453E-04 9,921E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 8,453E-04 9,873E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 8,597E-04 9,992E-03 ! cell cycle checkpoint GO:0000075 137 69 3,000 9,082E-04 0,0105052 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 9,316E-04 0,01072443 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 1,023E-03 0,01172396 ! hindbrain development GO:0030902 61 32 2,000 1,023E-03 0,0116684 ! succinate metabolic process GO:0006105 14 8 1,000 1,048E-03 0,01189003 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,048E-03 0,01183421 ! pigment granule organization GO:0048753 16 8 1,000 1,048E-03 0,01177891 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 1,048E-03 0,01172412 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 1,000 1,048E-03 0,01166984 ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,048E-03 0,01161606 ! melanin metabolic process GO:0006582 15 8 1,000 1,048E-03 0,01156278 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,048E-03 0,01150998 ! response to UV-B GO:0010224 16 8 1,000 1,048E-03 0,01145766 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,048E-03 0,01140582 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 1,048E-03 0,01135444 ! neuromuscular process controlling posture GO:0050884 14 8 1,000 1,048E-03 0,01130352 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 1,048E-03 0,01125306 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,121E-03 0,0119819 GO:0060326|cell chemotaxis, ! learning or memory GO:0007611 147 73 3,000 1,122E-03 0,01194076 ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,18E-03 0,01250716 GO:0090046|regulation of transcription regulator activity, ! organelle localization GO:0051640 136 74 3,000 1,18E-03 0,0124523 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 1,223E-03 0,01285323 ! placenta development GO:0001890 53 34 2,000 1,223E-03 0,01279735 ! regulation of muscle development GO:0048634 70 35 2,000 1,332E-03 0,0138732 ! regulation of synaptic plasticity GO:0048167 64 35 2,000 1,332E-03 0,0138134 ! regulation of developmental growth GO:0048638 15 9 1,000 1,341E-03 0,01385257 ! GTP metabolic process GO:0046039 9 9 1,000 1,341E-03 0,01379337 ! microtubule bundle formation GO:0001578 21 9 1,000 1,341E-03 0,01373467 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,341E-03 0,01367648 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 1,000 1,341E-03 0,01361877 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! T cell selection GO:0045058 23 9 1,000 1,341E-03 0,01356155 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,341E-03 0,0135048 GO:0006600|creatine metabolic process, ! receptor clustering GO:0043113 18 9 1,000 1,341E-03 0,01344853 ! behavioral fear response GO:0001662 22 9 1,000 1,341E-03 0,01339273 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,341E-03 0,01333739 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,341E-03 0,0132825 ! response to amine stimulus GO:0014075 13 9 1,000 1,341E-03 0,01322807 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,341E-03 0,01317407 ! induction of an organ GO:0001759 14 9 1,000 1,341E-03 0,01312052 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,341E-03 0,0130674 ! regulation of synaptogenesis GO:0051963 15 9 1,000 1,341E-03 0,01301471 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,341E-03 0,01296244 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,446E-03 0,01392069 ! regulation of synaptic transmission GO:0050804 134 79 3,000 1,504E-03 0,01441948 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 1,567E-03 0,01496054 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,567E-03 0,0149014 ! response to hypoxia GO:0001666 171 81 3,000 1,65E-03 0,01562739 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,67E-03 0,01575723 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,67E-03 0,01569568 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,67E-03 0,01563461 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,67E-03 0,01557401 ! B cell proliferation GO:0042100 18 10 1,000 1,67E-03 0,01551388 ! epithelial cell development GO:0002064 20 10 1,000 1,67E-03 0,01545421 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,67E-03 0,015395 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 1,67E-03 0,01533624 ! midbrain development GO:0030901 13 10 1,000 1,67E-03 0,01527792 ! oocyte development GO:0048599 17 10 1,000 1,67E-03 0,01522005 ! blastocyst formation GO:0001825 17 10 1,000 1,67E-03 0,01516262 ! response to nicotine GO:0035094 20 10 1,000 1,67E-03 0,01510562 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,694E-03 0,01526078 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 2,000 1,694E-03 0,01520384 ! response to oxygen levels GO:0070482 176 83 3,000 1,805E-03 0,01614232 ! learning GO:0007612 77 39 2,000 1,826E-03 0,01627465 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 1,826E-03 0,01621459 ! negative regulation of transport GO:0051051 153 84 3,000 1,886E-03 0,0166822 ! regulation of transmission of nerve impulse GO:0051969 141 84 3,000 1,886E-03 0,01662109 ! negative regulation of binding GO:0051100 72 40 2,000 1,965E-03 0,01725873 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 1,965E-03 0,01719597 ! cytokinesis GO:0000910 72 40 2,000 1,965E-03 0,01713367 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,033E-03 0,01765693 ! response to pain GO:0048265 24 11 1,000 2,033E-03 0,01759342 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,033E-03 0,01753036 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 2,033E-03 0,01746775 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,033E-03 0,01740559 ! indolalkylamine metabolic process GO:0006586 17 11 1,000 2,033E-03 0,01734386 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! negative regulation of ossification GO:0030279 26 11 1,000 2,033E-03 0,01728258 ! purine ribonucleotide catabolic process GO:0009154 17 11 1,000 2,033E-03 0,01722172 ! DNA methylation GO:0006306 19 11 1,000 2,033E-03 0,0171613 GO:0006305|DNA alkylation, ! oocyte differentiation GO:0009994 18 11 1,000 2,033E-03 0,01710129 ! thymus development GO:0048538 27 11 1,000 2,033E-03 0,01704171 ! developmental induction GO:0031128 19 11 1,000 2,033E-03 0,01698253 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of synapse organization GO:0050807 17 11 1,000 2,033E-03 0,01692377 ! mitochondrion organization GO:0007005 148 86 3,000 2,056E-03 0,01705583 ! regulation of T cell proliferation GO:0042129 71 41 2,000 2,111E-03 0,01745393 ! regulation of T cell differentiation GO:0045580 70 41 2,000 2,111E-03 0,01739415 ! regulation of DNA binding GO:0051101 155 88 3,000 2,236E-03 0,0183603 ! gland development GO:0048732 206 88 3,000 2,236E-03 0,01829785 ! regulation of neurological system process GO:0031644 148 88 3,000 2,236E-03 0,01823583 ! response to reactive oxygen species GO:0000302 67 42 2,000 2,263E-03 0,01839527 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 2,263E-03 0,01833333 ! neuron migration GO:0001764 79 42 2,000 2,263E-03 0,01827181 ! regulation of cell adhesion GO:0030155 212 89 3,000 2,33E-03 0,01874839 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 2,422E-03 0,01942284 ! folic acid and derivative biosynthetic process GO:0009396 21 12 1,000 2,429E-03 0,01941938 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,429E-03 0,01935508 ! hippocampus development GO:0021766 26 12 1,000 2,429E-03 0,0192912 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,429E-03 0,01922774 ! entry into host cell GO:0030260 32 12 1,000 2,429E-03 0,0191647 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 1,000 2,429E-03 0,01910207 ! histone acetylation GO:0016573 26 12 1,000 2,429E-03 0,01903985 ! gland morphogenesis GO:0022612 29 12 1,000 2,429E-03 0,01897803 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,429E-03 0,01891661 ! T cell homeostasis GO:0043029 25 12 1,000 2,429E-03 0,01885559 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 2,429E-03 0,01879496 ! spleen development GO:0048536 22 12 1,000 2,429E-03 0,01873472 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,429E-03 0,01867487 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of synapse structure and activity GO:0050803 18 12 1,000 2,429E-03 0,01861539 ! male sex differentiation GO:0046661 76 44 2,000 2,587E-03 0,01976153 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,733E-03 0,02081052 ! regulation of membrane potential GO:0042391 164 93 3,000 2,733E-03 0,02074487 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 2,733E-03 0,02067964 ! leukocyte migration GO:0050900 68 45 2,000 2,759E-03 0,02081289 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 2,759E-03 0,02074785 ! ribonucleotide catabolic process GO:0009261 20 13 1,000 2,859E-03 0,02143256 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,859E-03 0,021366 ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 2,859E-03 0,02129985 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,859E-03 0,02123411 GO:0000725|recombinational repair, ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,859E-03 0,02116877 ! exocrine system development GO:0035272 32 13 1,000 2,859E-03 0,02110384 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,859E-03 0,0210393 ! embryonic placenta development GO:0001892 23 13 1,000 2,859E-03 0,02097516 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,859E-03 0,0209114 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,939E-03 0,02142535 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,939E-03 0,02136062 ! positive regulation of defense response GO:0031349 76 47 2,000 3,125E-03 0,02264534 ! regulation of protein localization GO:0032880 176 97 3,000 3,182E-03 0,02299021 ! cellular component disassembly GO:0022411 86 48 2,000 3,318E-03 0,02390175 ! activation of caspase activity GO:0006919 84 48 2,000 3,318E-03 0,02383041 ! regulation of inflammatory response GO:0050727 75 48 2,000 3,318E-03 0,02375948 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 3,318E-03 0,02368898 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,322E-03 0,02365029 ! pteridine and derivative biosynthetic process GO:0042559 19 14 1,000 3,322E-03 0,02358053 ! hair follicle morphogenesis GO:0031069 26 14 1,000 3,322E-03 0,02351117 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,322E-03 0,02344223 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,322E-03 0,02337368 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 3,322E-03 0,02330554 ! response to gamma radiation GO:0010332 28 14 1,000 3,322E-03 0,02323779 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 3,322E-03 0,02317043 ! male genitalia development GO:0030539 24 14 1,000 3,322E-03 0,02310346 ! regulation of cell projection organization GO:0031344 121 50 2,000 3,726E-03 0,02583569 ! neuromuscular process GO:0050905 99 50 2,000 3,726E-03 0,02576145 ! inner ear development GO:0048839 79 50 2,000 3,726E-03 0,02568764 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,726E-03 0,02561424 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,818E-03 0,02617112 ! heterophilic cell adhesion GO:0007157 39 15 1,000 3,818E-03 0,02609677 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 1,000 3,818E-03 0,02602284 ! regulation of exocytosis GO:0017157 22 15 1,000 3,818E-03 0,02594933 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,818E-03 0,02587623 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,818E-03 0,02580355 ! regulation of angiogenesis GO:0045765 114 52 2,000 4,163E-03 0,02805969 ! regulation of muscle contraction GO:0006937 81 52 2,000 4,163E-03 0,02798131 ! positive regulation of growth GO:0045927 90 52 2,000 4,163E-03 0,02790337 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 4,163E-03 0,02782586 ! cartilage development GO:0051216 90 52 2,000 4,163E-03 0,02774878 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 4,346E-03 0,02888298 GO:0031114|regulation of microtubule depolymerization, ! regulation of dephosphorylation GO:0035303 43 16 1,000 4,346E-03 0,02880341 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 4,346E-03 0,02872428 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 4,346E-03 0,02864558 ! startle response GO:0001964 28 16 1,000 4,346E-03 0,02856731 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,346E-03 0,02848947 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,346E-03 0,02841206 ! defense response to virus GO:0051607 37 16 1,000 4,346E-03 0,02833506 ! cell maturation GO:0048469 100 53 2,000 4,393E-03 0,02856858 ! response to UV GO:0009411 104 53 2,000 4,393E-03 0,02849158 ! positive regulation of caspase activity GO:0043280 95 55 2,000 4,876E-03 0,03153547 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 2,000 4,876E-03 0,03145092 ! aging GO:0007568 103 55 2,000 4,876E-03 0,03136683 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 4,876E-03 0,03128318 ! metencephalon development GO:0022037 30 17 1,000 4,905E-03 0,03138704 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,905E-03 0,03130378 ! signal complex assembly GO:0007172 41 17 1,000 4,905E-03 0,03122097 ! limbic system development GO:0021761 36 17 1,000 4,905E-03 0,03113859 ! regulation of viral genome replication GO:0045069 28 17 1,000 4,905E-03 0,03105665 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,905E-03 0,03097514 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,905E-03 0,03089405 ! regulation of protein binding GO:0043393 33 17 1,000 4,905E-03 0,03081339 ! genitalia development GO:0048806 30 17 1,000 4,905E-03 0,03073314 ! folic acid and derivative metabolic process GO:0006760 33 17 1,000 4,905E-03 0,03065332 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 4,905E-03 0,0305739 ! aromatic compound biosynthetic process GO:0019438 24 17 1,000 4,905E-03 0,0304949 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,905E-03 0,03041631 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,905E-03 0,03033812 ! regulation of DNA replication GO:0006275 101 56 2,000 5,129E-03 0,03163917 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 5,389E-03 0,03316118 ! positive regulation of cell migration GO:0030335 126 57 2,000 5,389E-03 0,03307658 ! lipid modification GO:0030258 97 57 2,000 5,389E-03 0,03299242 ! regulation of intracellular transport GO:0032386 101 57 2,000 5,389E-03 0,03290868 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,496E-03 0,03347531 ! epidermis morphogenesis GO:0048730 40 18 1,000 5,496E-03 0,03339077 ! long-chain fatty acid transport GO:0015909 31 18 1,000 5,496E-03 0,03330666 ! aromatic compound catabolic process GO:0019439 27 18 1,000 5,496E-03 0,03322298 ! positive regulation of synaptic transmission GO:0050806 28 18 1,000 5,496E-03 0,03313971 ! DNA catabolic process GO:0006308 86 59 2,000 5,934E-03 0,03569026 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 6,117E-03 0,03670403 ! lipid phosphorylation GO:0046834 35 19 1,000 6,117E-03 0,03661273 ! forelimb morphogenesis GO:0035136 32 19 1,000 6,117E-03 0,03652188 ! regulation of postsynaptic membrane potential GO:0060078 32 19 1,000 6,117E-03 0,03643148 ! cerebral cortex development GO:0021987 36 19 1,000 6,117E-03 0,03634152 ! pigmentation during development GO:0048066 41 19 1,000 6,117E-03 0,03625201 ! actin filament bundle formation GO:0051017 42 19 1,000 6,117E-03 0,03616294 ! neuromuscular junction development GO:0007528 34 19 1,000 6,117E-03 0,03607431 ! response to lipopolysaccharide GO:0032496 30 19 1,000 6,117E-03 0,0359861 ! prostaglandin metabolic process GO:0006693 37 19 1,000 6,117E-03 0,03589833 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 1,000 6,117E-03 0,03581099 ! cellular pigmentation GO:0033059 36 19 1,000 6,117E-03 0,03572407 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 6,117E-03 0,03563757 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 1,000 6,117E-03 0,03555149 ! purine nucleotide catabolic process GO:0006195 29 19 1,000 6,117E-03 0,03546582 ! proximal/distal pattern formation GO:0009954 32 19 1,000 6,117E-03 0,03538057 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 6,117E-03 0,03529572 ! regulation of heart contraction GO:0008016 110 60 2,000 6,218E-03 0,03578883 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 6,218E-03 0,03570341 ! regulation of protein complex assembly GO:0043254 117 61 2,000 6,51E-03 0,03729191 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,769E-03 0,03868711 ! pteridine and derivative metabolic process GO:0042558 29 20 1,000 6,769E-03 0,03859543 ! protein amino acid acetylation GO:0006473 39 20 1,000 6,769E-03 0,03850419 ! fatty acid beta-oxidation GO:0006635 34 20 1,000 6,769E-03 0,03841338 ! positive regulation of neurological system process GO:0031646 32 20 1,000 6,769E-03 0,03832299 ! regulation of homeostatic process GO:0032844 134 62 2,000 6,81E-03 0,03846209 ! multicellular organism reproduction GO:0032504 111 64 2,000 7,435E-03 0,04189225 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 2,000 7,435E-03 0,04179437 ! glycerol metabolic process GO:0006071 34 21 1,000 7,452E-03 0,04179173 ! ovarian follicle development GO:0001541 35 21 1,000 7,452E-03 0,04169454 ! neurotransmitter metabolic process GO:0042133 34 21 1,000 7,452E-03 0,0415978 ! cell aging GO:0007569 44 21 1,000 7,452E-03 0,04150151 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 7,452E-03 0,04140566 ! oogenesis GO:0048477 36 21 1,000 7,452E-03 0,04131026 ! DNA modification GO:0006304 34 21 1,000 7,452E-03 0,04121529 ! collagen catabolic process GO:0030574 28 21 1,000 7,452E-03 0,04112076 ! gut development GO:0048565 39 21 1,000 7,452E-03 0,04102666 ! developmental maturation GO:0021700 116 66 2,000 8,092E-03 0,04445234 ! cell projection assembly GO:0030031 120 66 2,000 8,092E-03 0,04435108 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 8,164E-03 0,04463979 ! regeneration GO:0031099 41 22 1,000 8,164E-03 0,04453856 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 8,164E-03 0,0444378 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 8,164E-03 0,04433748 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 8,164E-03 0,04423763 ! ureteric bud development GO:0001657 43 22 1,000 8,164E-03 0,04413822 ! renal system process GO:0003014 41 22 1,000 8,164E-03 0,04403925 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 8,164E-03 0,04394073 ! positive regulation of B cell activation GO:0050871 38 22 1,000 8,164E-03 0,04384265 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 8,164E-03 0,043745 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 8,164E-03 0,04364779 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 8,164E-03 0,04355101 ! protein stabilization GO:0050821 39 22 1,000 8,164E-03 0,04345466 ! homeostasis of number of cells GO:0048872 114 67 2,000 8,434E-03 0,0447927 ! positive regulation of DNA replication GO:0045740 43 23 1,000 8,905E-03 0,0471914 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 8,905E-03 0,04708768 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,905E-03 0,04698442 ! gluconeogenesis GO:0006094 33 23 1,000 8,905E-03 0,04688161 ! leukocyte adhesion GO:0007159 50 23 1,000 8,905E-03 0,04677925 ! visual behavior GO:0007632 42 23 1,000 8,905E-03 0,04667733 ! regulation of DNA recombination GO:0000018 48 23 1,000 8,905E-03 0,04657586 ! regulation of viral reproduction GO:0050792 38 23 1,000 8,905E-03 0,04647483 ! fatty acid transport GO:0015908 44 23 1,000 8,905E-03 0,04637423 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 8,905E-03 0,04627407 ! urogenital system development GO:0001655 137 69 2,000 9,141E-03 0,04739951 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 9,675E-03 0,05005997 GO:0016444|somatic cell DNA recombination, ! response to corticosteroid stimulus GO:0031960 41 24 1,000 9,675E-03 0,04995254 ! lymphocyte proliferation GO:0046651 48 24 1,000 9,675E-03 0,04984558 ! membrane depolarization GO:0051899 39 24 1,000 9,675E-03 0,04973907 ! pallium development GO:0021543 49 24 1,000 9,675E-03 0,04963302 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 9,675E-03 0,04952741 ! leukocyte homeostasis GO:0001776 44 24 1,000 9,675E-03 0,04942226 ! alditol metabolic process GO:0019400 38 24 1,000 9,675E-03 0,04931755 ! reproductive structure development GO:0048608 113 71 2,000 9,882E-03 0,05026799 ! regulation of caspase activity GO:0043281 122 72 2,000 0,01026562 0,05210779 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 0,01047363 0,05305169 ! myelination GO:0042552 45 25 1,000 0,01047363 0,05294024 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 0,01047363 0,05282925 ! vasculogenesis GO:0001570 46 25 1,000 0,01047363 0,05271873 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 0,01047363 0,05260867 ! interaction with host GO:0051701 62 25 1,000 0,01047363 0,05249907 ! somitogenesis GO:0001756 43 25 1,000 0,01047363 0,05238992 ! immunoglobulin production GO:0002377 55 25 1,000 0,01047363 0,05228123 GO:0002440|production of molecular mediator of immune response, ! regulation of blood pressure GO:0008217 125 73 2,000 0,01065751 0,05308897 ! meiosis GO:0007126 121 74 2,000 0,01105797 0,05496998 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01105797 0,05485664 ! initiation of viral infection GO:0019059 57 26 1,000 0,01130049 0,05594441 ! pyruvate metabolic process GO:0006090 38 26 1,000 0,01130049 0,05582954 ! molting cycle process GO:0022404 50 26 1,000 0,01130049 0,05571513 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01130049 0,05560119 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 0,01130049 0,05548772 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01130049 0,05537471 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01130049 0,05526216 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 0,01130049 0,05515007 ! somatic diversification of immune receptors GO:0002200 56 26 1,000 0,01130049 0,05503843 ! blastocyst development GO:0001824 49 26 1,000 0,01130049 0,05492724 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01130049 0,0548165 GO:0032943|mononuclear cell proliferation, ! cell-matrix adhesion GO:0007160 163 75 2,000 0,01146703 0,05551242 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01146703 0,05540095 ! meiotic cell cycle GO:0051321 122 75 2,000 0,01146703 0,05528992 ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,01188472 0,05718928 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01188472 0,05707513 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01215514 0,05825751 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01215514 0,05814169 ! fat cell differentiation GO:0045444 50 27 1,000 0,01215514 0,05802633 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01215514 0,05791143 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 0,01215514 0,05779698 ! male gonad development GO:0008584 44 27 1,000 0,01215514 0,05768298 ! response to toxin GO:0009636 47 27 1,000 0,01215514 0,05756943 ! blood coagulation GO:0007596 146 78 2,000 0,01274612 0,06024984 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,01274612 0,0601317 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01303721 0,06138458 ! lipid oxidation GO:0034440 43 28 1,000 0,01303721 0,06126469 GO:0019395|fatty acid oxidation, ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01318988 0,0618613 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 0,01318988 0,06174095 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01394632 0,06515502 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01394632 0,06502875 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01394632 0,06490297 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01394632 0,06477768 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01394632 0,06465287 ! tissue homeostasis GO:0001894 48 29 1,000 0,01394632 0,06452853 GO:0048871|multicellular organismal homeostasis, ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01410363 0,06513114 ! response to nutrient GO:0007584 125 82 2,000 0,01457366 0,06717285 ! ensheathment of neurons GO:0007272 57 30 1,000 0,0148821 0,06846337 GO:0008366|axon ensheathment, ! response to heat GO:0009408 50 30 1,000 0,0148821 0,06833272 ! hemostasis GO:0007599 158 84 2,000 0,01554014 0,07121826 ! regulation of ligase activity GO:0051340 142 84 2,000 0,01554014 0,07108286 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01584421 0,07233618 ! collagen metabolic process GO:0032963 45 31 1,000 0,01584421 0,07219918 ! ovulation cycle process GO:0022602 49 31 1,000 0,01584421 0,0720627 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01584421 0,07192673 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01584421 0,07179128 ! fatty acid catabolic process GO:0009062 48 31 1,000 0,01584421 0,07165633 ! tube morphogenesis GO:0035239 176 86 2,000 0,01654196 0,07467158 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01683227 0,07583978 ! spindle organization GO:0007051 46 32 1,000 0,01683227 0,07569802 ! metanephros development GO:0001656 74 32 1,000 0,01683227 0,0755568 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01683227 0,07541609 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01683227 0,07527592 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01683227 0,07513626 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01683227 0,07499712 ! ovulation cycle GO:0042698 51 32 1,000 0,01683227 0,07485849 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01683227 0,07472037 ! regulation of protein transport GO:0051223 154 87 2,000 0,01705615 0,07557478 GO:0070201|regulation of establishment of protein localization, ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01784593 0,07892889 ! post-embryonic development GO:0009791 69 33 1,000 0,01784593 0,07878406 ! cell fate specification GO:0001708 52 33 1,000 0,01784593 0,07863977 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01784593 0,07849601 ! sex differentiation GO:0007548 145 90 2,000 0,01865202 0,0818919 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01888484 0,08276309 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,01888484 0,08261261 ! mismatch repair GO:0006298 46 34 1,000 0,01888484 0,08246268 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,01888484 0,08231329 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01888484 0,08216444 ! regulation of defense response GO:0031347 149 92 2,000 0,01976043 0,08581876 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01994866 0,08648012 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01994866 0,08632458 ! odontogenesis GO:0042476 66 35 1,000 0,01994866 0,08616959 ! female gonad development GO:0008585 58 35 1,000 0,01994866 0,08601517 ! telencephalon development GO:0021537 68 35 1,000 0,01994866 0,0858613 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01994866 0,08570797 ! biogenic amine metabolic process GO:0006576 155 94 2,000 0,02090449 0,08965457 ! female pregnancy GO:0007565 164 94 2,000 0,02090449 0,08949504 ! transcription initiation GO:0006352 153 94 2,000 0,02090449 0,08933608 ! regulation of T cell activation GO:0050863 158 94 2,000 0,02090449 0,08917769 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,02103702 0,08958419 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,02103702 0,08942592 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02103702 0,0892682 ! positive regulation of cell development GO:0010720 80 36 1,000 0,02103702 0,08911104 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,02103702 0,08895443 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,02103702 0,08879837 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,02103702 0,08864285 ! meiosis I GO:0007127 65 37 1,000 0,0221496 0,09316771 ! glycogen metabolic process GO:0005977 61 37 1,000 0,0221496 0,09300511 ! pigment metabolic process GO:0042440 80 37 1,000 0,0221496 0,09284308 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02328604 0,09743691 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,02328604 0,09726775 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02328604 0,09709917 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 1,000 0,02328604 0,09693118 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,02328604 0,09676377 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02328604 0,09659693 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02328604 0,09643067 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,02328604 0,09626499 GO:0006073|cellular glucan metabolic process, ! carboxylic acid catabolic process GO:0046395 156 98 2,000 0,02329971 0,09615625 GO:0016054|organic acid catabolic process, ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02392082 0,0985505 GO:0060538|skeletal muscle organ development, ! mammary gland development GO:0030879 86 39 1,000 0,02444603 0,10054213 ! ear morphogenesis GO:0042471 60 39 1,000 0,02444603 0,10037055 ! segmentation GO:0035282 67 39 1,000 0,02444603 0,10019956 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02444603 0,10002916 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,02444603 0,09985933 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,02562922 0,10451508 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02562922 0,10433823 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 0,02562922 0,10416198 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,02683528 0,10887973 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02683528 0,10869643 ! T cell differentiation GO:0030217 81 41 1,000 0,02683528 0,10851375 ! female gamete generation GO:0007292 61 41 1,000 0,02683528 0,10833168 ! polyol metabolic process GO:0019751 66 41 1,000 0,02683528 0,10815022 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02683528 0,10796936 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02806389 0,11272406 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02806389 0,11253619 ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,02806389 0,11234894 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,02806389 0,11216231 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02806389 0,11197631 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02931472 0,11677354 ! glucose transport GO:0015758 65 43 1,000 0,02931472 0,11658053 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02931472 0,11638815 ! neural tube development GO:0021915 77 43 1,000 0,02931472 0,11619641 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 0,02931472 0,11600529 ! hexose transport GO:0008645 67 44 1,000 0,03058746 0,12084306 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 1,000 0,03058746 0,12064496 ! biopolymer methylation GO:0043414 84 44 1,000 0,03058746 0,1204475 ! B cell differentiation GO:0030183 107 44 1,000 0,03058746 0,12025069 ! developmental growth GO:0048589 82 44 1,000 0,03058746 0,12005453 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03058746 0,119859 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03066445 0,11996533 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03066445 0,11977058 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03066445 0,11957646 ! neuron fate determination GO:0048664 7 5 0,000 0,03066445 0,11938298 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03066445 0,11919011 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03066445 0,11899787 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,03066445 0,11880625 ! polyol transport GO:0015791 12 5 0,000 0,03066445 0,11861524 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03066445 0,11842485 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03066445 0,11823506 ! response to superoxide GO:0000303 10 5 0,000 0,03066445 0,11804589 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03066445 0,11785731 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03066445 0,11766934 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03066445 0,11748197 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03066445 0,1172952 ! female meiosis GO:0007143 7 5 0,000 0,03066445 0,11710901 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03066445 0,11692342 ! cobalt ion transport GO:0006824 11 5 0,000 0,03066445 0,11673842 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03066445 0,11655399 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03066445 0,11637016 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03066445 0,1161869 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03066445 0,11600421 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03066445 0,1158221 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03066445 0,11564056 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03066445 0,11545959 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03066445 0,11527919 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03066445 0,11509934 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03066445 0,11492006 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03066445 0,11474134 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03066445 0,11456317 ! negative chemotaxis GO:0050919 14 5 0,000 0,03066445 0,11438555 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03066445 0,11420848 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03066445 0,11403196 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03066445 0,11385599 ! behavioral response to pain GO:0048266 9 5 0,000 0,03066445 0,11368055 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03066445 0,11350566 ! Notch receptor processing GO:0007220 8 5 0,000 0,03066445 0,1133313 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03066445 0,11315748 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,03066445 0,11298419 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03066445 0,11281144 ! copulation GO:0007620 9 5 0,000 0,03066445 0,1126392 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03066445 0,1124675 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03066445 0,11229631 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03066445 0,11212565 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03066445 0,11195551 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03066445 0,11178588 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03066445 0,11161676 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03066445 0,11144816 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03066445 0,11128006 ! grooming behavior GO:0007625 6 5 0,000 0,03066445 0,11111247 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03066445 0,11094538 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03066445 0,1107788 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03066445 0,11061271 ! response to protozoan GO:0001562 10 5 0,000 0,03066445 0,11044712 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,03066445 0,11028203 ! lymph vessel development GO:0001945 10 5 0,000 0,03066445 0,11011743 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03066445 0,10995332 ! endochondral ossification GO:0001958 16 5 0,000 0,03066445 0,1097897 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03066445 0,10962657 ! parathyroid gland development GO:0060017 13 5 0,000 0,03066445 0,10946391 ! anagen GO:0042640 6 5 0,000 0,03066445 0,10930175 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03066445 0,10914006 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03066445 0,10897885 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03066445 0,10881811 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03066445 0,10865785 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03066445 0,10849806 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03066445 0,10833874 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03066445 0,10817988 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03066445 0,10802149 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03066445 0,10786357 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03066445 0,1077061 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03066445 0,10754909 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03066445 0,10739255 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03066445 0,10723645 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03066445 0,10708081 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03066445 0,10692562 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03066445 0,10677088 ! histidine catabolic process GO:0006548 6 5 0,000 0,03066445 0,10661659 GO:0009077|histidine family amino acid catabolic process, ! microvillus organization GO:0032528 7 5 0,000 0,03066445 0,10646274 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03066445 0,10630934 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03066445 0,10615637 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03066445 0,10600385 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03066445 0,10585176 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03066445 0,10570011 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03066445 0,1055489 ! polyol catabolic process GO:0046174 7 5 0,000 0,03066445 0,10539811 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03066445 0,10524776 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03066445 0,10509783 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03066445 0,10494833 ! mitochondrial fission GO:0000266 8 5 0,000 0,03066445 0,10479926 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03066445 0,10465061 ! mRNA transcription GO:0009299 9 5 0,000 0,03066445 0,10450238 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03066445 0,10435457 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03066445 0,10420717 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03066445 0,1040602 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03066445 0,10391363 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03066445 0,10376748 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03066445 0,10362174 ! response to food GO:0032094 6 5 0,000 0,03066445 0,10347641 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03066445 0,10333148 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03066445 0,10318696 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03066445 0,10304285 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03066445 0,10289913 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03066445 0,10275582 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,03066445 0,1026129 ! forebrain neuron development GO:0021884 13 5 0,000 0,03066445 0,10247039 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03066445 0,10232826 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,03066445 0,10218654 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03066445 0,1020452 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03066445 0,10190425 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03066445 0,10176369 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03066445 0,10162352 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03066445 0,10148374 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03066445 0,10134434 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03066445 0,10120532 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03066445 0,10106668 ! basic amino acid transport GO:0015802 11 5 0,000 0,03066445 0,10092842 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03066445 0,10079054 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03066445 0,10065304 ! depyrimidination GO:0045008 10 5 0,000 0,03066445 0,10051591 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03066445 0,10037915 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03066445 0,10024277 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03066445 0,10010676 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03066445 0,09997111 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03066445 0,09983583 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03066445 0,09970092 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03066445 0,09956637 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03066445 0,09943218 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03066445 0,09929836 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03066445 0,09916489 ! response to arsenic GO:0046685 10 5 0,000 0,03066445 0,09903178 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03066445 0,09889903 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03066445 0,09876664 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03066445 0,0986346 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03066445 0,09850291 ! response to cadmium ion GO:0046686 7 5 0,000 0,03066445 0,09837157 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03066445 0,09824058 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03066445 0,09810994 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03066445 0,09797965 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03066445 0,09784971 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03066445 0,0977201 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03066445 0,09759084 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03066445 0,09746193 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03066445 0,09733335 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03066445 0,09720511 ! embryonic cleavage GO:0040016 6 5 0,000 0,03066445 0,09707721 ! peroxisome fission GO:0016559 5 5 0,000 0,03066445 0,09694964 ! histone demethylation GO:0016577 10 5 0,000 0,03066445 0,09682241 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03066445 0,09669552 ! mitotic recombination GO:0006312 9 5 0,000 0,03066445 0,09656895 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03066445 0,09644272 ! metaphase plate congression GO:0051310 7 5 0,000 0,03066445 0,09631681 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03066445 0,09619124 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03066445 0,09606599 ! enteric nervous system development GO:0048484 8 5 0,000 0,03066445 0,09594106 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03066445 0,09581647 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03066445 0,09569219 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03066445 0,09556824 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03066445 0,0954446 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03066445 0,09532129 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03066445 0,0951983 ! plasminogen activation GO:0031639 5 5 0,000 0,03066445 0,09507562 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03066445 0,09495325 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03066445 0,09483121 ! metaphase GO:0051323 8 5 0,000 0,03066445 0,09470947 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03066445 0,09458805 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03066445 0,09446694 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03066445 0,09434614 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03066445 0,09422564 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03066445 0,09410546 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03066445 0,09398558 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03066445 0,093866 ! response to redox state GO:0051775 5 5 0,000 0,03066445 0,09374673 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03066445 0,09362776 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03066445 0,0935091 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03066445 0,09339073 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03066445 0,09327267 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03066445 0,0931549 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03066445 0,09303743 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03066445 0,09292025 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03066445 0,09280337 ! striatum development GO:0021756 9 5 0,000 0,03066445 0,09268678 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03066445 0,09257049 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03066445 0,09245448 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03066445 0,09233877 ! glial cell migration GO:0008347 11 5 0,000 0,03066445 0,09222335 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03066445 0,09210821 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03066445 0,09199336 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03066445 0,0918788 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03066445 0,09176453 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03066445 0,09165053 ! neuroprotection GO:0043526 6 5 0,000 0,03066445 0,09153682 ! neural plate development GO:0001840 8 5 0,000 0,03066445 0,09142339 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03066445 0,09131025 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03066445 0,09119738 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03066445 0,09108479 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03066445 0,09097248 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03066445 0,09086044 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03066445 0,09074868 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03066445 0,0906372 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03066445 0,09052599 ! spindle assembly GO:0051225 6 5 0,000 0,03066445 0,09041505 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03066445 0,09030438 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03066445 0,09019398 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 6 5 0,000 0,03066445 0,09008386 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03066445 0,089974 ! organ regeneration GO:0031100 7 5 0,000 0,03066445 0,08986441 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03066445 0,08975508 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03066445 0,08964603 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03066445 0,08953723 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,03188178 0,09297887 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03188178 0,09286631 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,03188178 0,09275401 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,03319738 0,09646485 ! endosome transport GO:0016197 108 47 1,000 0,03453394 0,10022757 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03453394 0,10010682 ! methylation GO:0032259 90 47 1,000 0,03453394 0,09998635 ! protein homooligomerization GO:0051260 76 47 1,000 0,03453394 0,09986618 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,03589115 0,1036664 ! mitochondrial transport GO:0006839 82 48 1,000 0,03589115 0,1035421 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03668417 0,10570314 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03668417 0,1055767 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03668417 0,10545056 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03668417 0,10532473 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03668417 0,10519919 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03668417 0,10507395 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03668417 0,10494901 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03668417 0,10482437 ! response to oxygen radical GO:0000305 11 6 0,000 0,03668417 0,10470002 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03668417 0,10457597 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03668417 0,10445221 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03668417 0,10432875 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03668417 0,10420557 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03668417 0,10408269 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03668417 0,10396009 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03668417 0,10383779 ! forebrain regionalization GO:0021871 8 6 0,000 0,03668417 0,10371577 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03668417 0,10359404 ! male meiosis GO:0007140 7 6 0,000 0,03668417 0,10347259 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03668417 0,10335143 ! response to zinc ion GO:0010043 9 6 0,000 0,03668417 0,10323055 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03668417 0,10310995 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03668417 0,10298964 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03668417 0,1028696 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03668417 0,10274985 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03668417 0,10263037 ! malate metabolic process GO:0006108 11 6 0,000 0,03668417 0,10251117 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03668417 0,10239225 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03668417 0,1022736 ! protein refolding GO:0042026 15 6 0,000 0,03668417 0,10215523 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03668417 0,10203713 ! opsonization GO:0008228 8 6 0,000 0,03668417 0,10191931 ! mating behavior GO:0007617 7 6 0,000 0,03668417 0,10180175 ! neuron remodeling GO:0016322 15 6 0,000 0,03668417 0,10168447 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03668417 0,10156746 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03668417 0,10145071 ! equilibrioception GO:0050957 14 6 0,000 0,03668417 0,10133424 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03668417 0,10121803 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03668417 0,10110208 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03668417 0,10098641 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03668417 0,10087099 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03668417 0,10075584 ! toxin metabolic process GO:0009404 11 6 0,000 0,03668417 0,10064096 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03668417 0,10052633 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03668417 0,10041197 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03668417 0,10029786 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03668417 0,10018402 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03668417 0,10007043 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03668417 0,0999571 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03668417 0,09984403 ! thymic T cell selection GO:0045061 12 6 0,000 0,03668417 0,09973121 ! protein lipoylation GO:0009249 10 6 0,000 0,03668417 0,09961865 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03668417 0,09950634 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03668417 0,09939428 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03668417 0,09928247 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03668417 0,09917092 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03668417 0,09905962 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03668417 0,09894857 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03668417 0,09883776 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03668417 0,0987272 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03668417 0,09861689 ! hyperosmotic response GO:0006972 9 6 0,000 0,03668417 0,09850683 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03668417 0,09839701 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03668417 0,09828744 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03668417 0,09817811 ! urea metabolic process GO:0019627 7 6 0,000 0,03668417 0,09806902 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03668417 0,09796018 ! neutrophil activation GO:0042119 8 6 0,000 0,03668417 0,09785157 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03668417 0,09774321 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03668417 0,09763509 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03668417 0,0975272 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03668417 0,09741956 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03668417 0,09731215 ! neuron apoptosis GO:0051402 9 6 0,000 0,03668417 0,09720498 ! nucleoside salvage GO:0043174 9 6 0,000 0,03668417 0,09709804 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03668417 0,09699134 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03668417 0,09688487 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03668417 0,09677864 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03668417 0,09667264 ! carnitine transport GO:0015879 10 6 0,000 0,03668417 0,09656687 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03668417 0,09646133 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03668417 0,09635603 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03668417 0,09625095 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03668417 0,0961461 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03668417 0,09604148 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03668417 0,09593709 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03668417 0,09583292 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03668417 0,09572898 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03668417 0,09562527 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03668417 0,09552177 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03668417 0,09541851 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 11 6 0,000 0,03668417 0,09531546 ! astrocyte development GO:0014002 15 6 0,000 0,03668417 0,09521264 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03668417 0,09511004 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03668417 0,09500766 ! interaction with symbiont GO:0051702 13 6 0,000 0,03668417 0,09490551 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03668417 0,09480357 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03668417 0,09470185 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03668417 0,09460034 ! response to copper ion GO:0046688 10 6 0,000 0,03668417 0,09449906 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03668417 0,09439799 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03668417 0,09429714 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03668417 0,0941965 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03668417 0,09409608 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03668417 0,09399587 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03668417 0,09389587 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03668417 0,09379609 ! hair follicle maturation GO:0048820 7 6 0,000 0,03668417 0,09369652 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03668417 0,09359716 ! Schwann cell development GO:0014044 15 6 0,000 0,03668417 0,09349801 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03668417 0,09339907 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03668417 0,09330034 ! subpallium development GO:0021544 10 6 0,000 0,03668417 0,09320182 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03668417 0,0931035 ! histone ubiquitination GO:0016574 8 6 0,000 0,03668417 0,0930054 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03668417 0,09290749 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03668417 0,0928098 ! G2 phase GO:0051319 16 6 0,000 0,03668417 0,09271231 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03668417 0,09261503 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03668417 0,09251795 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03668417 0,09242107 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03668417 0,09232439 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03668417 0,09222792 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03668417 0,09213165 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03668417 0,09203558 ! receptor internalization GO:0031623 10 6 0,000 0,03668417 0,09193971 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03668417 0,09184404 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03668417 0,09174857 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03668417 0,09165329 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03668417 0,09155822 ! protein destabilization GO:0031648 9 6 0,000 0,03668417 0,09146334 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03668417 0,09136865 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03668417 0,09127417 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03668417 0,09117988 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03668417 0,09108578 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03668417 0,09099188 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03668417 0,09089817 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03668417 0,09080465 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03668417 0,09071133 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03668417 0,09061819 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03668417 0,09052525 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03668417 0,0904325 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03668417 0,09033994 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03668417 0,09024757 ! catecholamine transport GO:0051937 9 6 0,000 0,03668417 0,09015538 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03668417 0,09006339 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03668417 0,08997158 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03668417 0,08987996 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03668417 0,08978852 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03668417 0,08969728 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03668417 0,08960621 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03668417 0,08951533 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03668417 0,08942464 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03668417 0,08933413 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03668417 0,0892438 ! regulation of action potential GO:0001508 95 49 1,000 0,03726872 0,09057427 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03726872 0,09048288 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03726872 0,09039166 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,03726872 0,09030063 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03726872 0,09020979 ! regulation of ossification GO:0030278 117 50 1,000 0,03866632 0,09349867 ! histone modification GO:0016570 91 50 1,000 0,03866632 0,0934048 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03866632 0,09331111 ! positive regulation of binding GO:0051099 78 51 1,000 0,04008368 0,09663461 ! viral infectious cycle GO:0019058 99 51 1,000 0,04008368 0,09653788 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,04008368 0,09644134 ! vesicle organization GO:0016050 107 51 1,000 0,04008368 0,09634499 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,04008368 0,09624884 ! membrane fusion GO:0006944 110 52 1,000 0,04152049 0,0995995 ! covalent chromatin modification GO:0016569 101 52 1,000 0,04152049 0,0995003 ! synapse organization GO:0050808 85 52 1,000 0,04152049 0,09940129 ! tRNA transcription GO:0009304 14 7 0,000 0,04266671 0,10204383 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04266671 0,1019425 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04266671 0,10184136 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04266671 0,10174043 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04266671 0,1016397 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04266671 0,10153916 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04266671 0,10143883 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04266671 0,10133869 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04266671 0,10123875 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04266671 0,10113901 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04266671 0,10103946 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04266671 0,10094011 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04266671 0,10084096 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04266671 0,100742 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04266671 0,10064323 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04266671 0,10054466 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04266671 0,10044628 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04266671 0,10034809 ! glycolipid transport GO:0046836 10 7 0,000 0,04266671 0,10025009 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04266671 0,10015229 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04266671 0,10005467 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04266671 0,09995725 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04266671 0,09986001 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04266671 0,09976297 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04266671 0,09966611 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04266671 0,09956944 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04266671 0,09947296 ! mRNA stabilization GO:0048255 18 7 0,000 0,04266671 0,09937667 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04266671 0,09928056 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04266671 0,09918463 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04266671 0,09908889 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04266671 0,09899334 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04266671 0,09889797 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04266671 0,09880279 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04266671 0,09870778 ! rhythmic behavior GO:0007622 15 7 0,000 0,04266671 0,09861296 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04266671 0,09851833 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04266671 0,09842387 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04266671 0,09832959 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04266671 0,0982355 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04266671 0,09814158 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04266671 0,09804785 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04266671 0,09795429 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04266671 0,09786091 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04266671 0,09776771 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04266671 0,09767469 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04266671 0,09758184 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04266671 0,09748917 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04266671 0,09739667 ! spinal cord patterning GO:0021511 13 7 0,000 0,04266671 0,09730436 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04266671 0,09721221 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04266671 0,09712024 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04266671 0,09702845 ! adrenal gland development GO:0030325 17 7 0,000 0,04266671 0,09693682 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04266671 0,09684537 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04266671 0,0967541 ! ovulation GO:0030728 9 7 0,000 0,04266671 0,09666299 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04266671 0,09657206 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04266671 0,09648129 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04266671 0,0963907 ! microtubule nucleation GO:0007020 20 7 0,000 0,04266671 0,09630028 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04266671 0,09621002 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04266671 0,09611994 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04266671 0,09603002 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04266671 0,09594028 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04266671 0,0958507 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04266671 0,09576128 ! galactose metabolic process GO:0006012 13 7 0,000 0,04266671 0,09567204 ! vesicle fusion GO:0006906 17 7 0,000 0,04266671 0,09558296 ! response to dietary excess GO:0002021 8 7 0,000 0,04266671 0,09549404 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04266671 0,09540529 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04266671 0,09531671 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04266671 0,09522829 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04266671 0,09514003 ! purine salvage GO:0043101 10 7 0,000 0,04266671 0,09505194 ! nucleoside transport GO:0015858 8 7 0,000 0,04266671 0,09496401 ! parturition GO:0007567 14 7 0,000 0,04266671 0,09487624 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04266671 0,09478864 ! rRNA modification GO:0000154 14 7 0,000 0,04266671 0,09470119 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04266671 0,09461391 ! spindle checkpoint GO:0031577 15 7 0,000 0,04266671 0,09452679 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04266671 0,09443983 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04266671 0,09435303 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04266671 0,09426639 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04266671 0,0941799 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04266671 0,09409358 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04266671 0,09400741 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04266671 0,0939214 ! eating behavior GO:0042755 7 7 0,000 0,04266671 0,09383555 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04266671 0,09374986 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04266671 0,09366432 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04266671 0,09357894 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04266671 0,09349371 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04266671 0,09340864 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04266671 0,09332372 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04266671 0,09323896 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04266671 0,09315435 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04266671 0,0930699 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04266671 0,09298559 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04266671 0,09290144 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04266671 0,09281745 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04266671 0,0927336 ! regulation of meiosis GO:0040020 12 7 0,000 0,04266671 0,09264991 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04266671 0,09256636 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04266671 0,09248297 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04266671 0,09239973 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04266671 0,09231663 ! transcription termination GO:0006353 13 7 0,000 0,04266671 0,09223369 ! response to tumor cell GO:0002347 13 7 0,000 0,04266671 0,09215089 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04266671 0,09206825 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04266671 0,09198575 ! anaphase GO:0051322 17 7 0,000 0,04266671 0,0919034 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04266671 0,09182119 ! axonal fasciculation GO:0007413 18 7 0,000 0,04266671 0,09173914 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04266671 0,09165723 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04266671 0,09157546 ! diuresis GO:0030146 12 7 0,000 0,04266671 0,09149385 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04266671 0,09141237 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04266671 0,09133105 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04266671 0,09124986 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04266671 0,09116882 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04266671 0,09108793 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04266671 0,09100718 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04266671 0,09092657 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04266671 0,0908461 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04266671 0,09076578 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04266671 0,0906856 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04266671 0,09060556 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04266671 0,09052566 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04266671 0,0904459 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04266671 0,09036628 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04266671 0,0902868 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04266671 0,09020746 ! adult feeding behavior GO:0008343 9 7 0,000 0,04266671 0,09012827 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04266671 0,09004921 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04266671 0,08997028 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04266671 0,0898915 ! muscle adaptation GO:0043500 14 7 0,000 0,04266671 0,08981286 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04266671 0,08973435 ! retina homeostasis GO:0001895 12 7 0,000 0,04266671 0,08965598 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04266671 0,08957774 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04266671 0,08949965 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04266671 0,08942169 ! protein prenylation GO:0018342 18 7 0,000 0,04266671 0,08934386 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04266671 0,08926617 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04266671 0,08918861 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04266671 0,08911119 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,04297646 0,08968027 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04445129 0,09267748 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,04445129 0,09259724 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,04445129 0,09251713 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,04445129 0,09243717 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,04594471 0,09546024 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,04594471 0,09537788 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04594471 0,09529566 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04745642 0,09834637 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04745642 0,09826173 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04861228 0,10056849 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04861228 0,10048209 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,04861228 0,10039584 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04861228 0,10030974 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04861228 0,10022378 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04861228 0,10013797 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04861228 0,10005231 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04861228 0,0999668 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04861228 0,09988143 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04861228 0,09979621 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04861228 0,09971113 ! meiotic prophase I GO:0007128 13 8 0,000 0,04861228 0,0996262 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04861228 0,09954141 ! oligopeptide transport GO:0006857 15 8 0,000 0,04861228 0,09945676 ! UTP metabolic process GO:0046051 8 8 0,000 0,04861228 0,09937226 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04861228 0,09928791 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04861228 0,09920369 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04861228 0,09911962 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04861228 0,09903569 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04861228 0,09895191 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04861228 0,09886826 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04861228 0,09878476 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04861228 0,0987014 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04861228 0,09861817 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04861228 0,09853509 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04861228 0,09845215 ! reflex GO:0060004 16 8 0,000 0,04861228 0,09836935 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04861228 0,09828668 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04861228 0,09820416 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04861228 0,09812177 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04861228 0,09803953 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04861228 0,09795742 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04861228 0,09787544 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04861228 0,09779361 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04861228 0,09771191 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04861228 0,09763035 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04861228 0,09754892 ! histidine metabolic process GO:0006547 16 8 0,000 0,04861228 0,09746763 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04861228 0,09738647 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04861228 0,09730545 ! glycine catabolic process GO:0006546 13 8 0,000 0,04861228 0,09722457 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04861228 0,09714382 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04861228 0,0970632 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04861228 0,09698271 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04861228 0,09690236 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04861228 0,09682215 ! macrophage activation GO:0042116 12 8 0,000 0,04861228 0,09674206 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04861228 0,09666211 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04861228 0,09658229 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04861228 0,0965026 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04861228 0,09642304 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04861228 0,09634362 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04861228 0,09626432 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04861228 0,09618516 ! osteoblast development GO:0002076 16 8 0,000 0,04861228 0,09610612 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04861228 0,09602722 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04861228 0,09594844 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04861228 0,0958698 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04861228 0,09579128 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04861228 0,09571289 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04861228 0,09563463 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04861228 0,0955565 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04861228 0,09547849 ! intermediate filament organization GO:0045109 12 8 0,000 0,04861228 0,09540061 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04861228 0,09532286 ! cellular extravasation GO:0045123 12 8 0,000 0,04861228 0,09524524 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04861228 0,09516774 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04861228 0,09509037 ! response to antibiotic GO:0046677 11 8 0,000 0,04861228 0,09501312 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04861228 0,094936 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04861228 0,09485901 ! DNA topological change GO:0006265 12 8 0,000 0,04861228 0,09478213 ! response to tropane GO:0014073 15 8 0,000 0,04861228 0,09470539 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04861228 0,09462877 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04861228 0,09455227 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04861228 0,09447589 ! mast cell activation GO:0045576 14 8 0,000 0,04861228 0,09439964 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04861228 0,09432351 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04861228 0,0942475 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04861228 0,09417162 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04861228 0,09409586 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04861228 0,09402022 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04861228 0,0939447 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04861228 0,0938693 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04861228 0,09379403 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04861228 0,09371887 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04861228 0,09364384 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04861228 0,09356892 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04861228 0,09349413 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04861228 0,09341945 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04861228 0,0933449 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04861228 0,09327046 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04861228 0,09319614 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04861228 0,09312194 ! hormone catabolic process GO:0042447 17 8 0,000 0,04861228 0,09304785 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04861228 0,09297389 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04861228 0,09290004 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04861228 0,09282631 ! ATP catabolic process GO:0006200 11 8 0,000 0,04861228 0,0927527 ! blastocyst growth GO:0001832 19 8 0,000 0,04861228 0,0926792 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04861228 0,09260582 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04861228 0,09253256 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04861228 0,09245941 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04861228 0,09238638 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04861228 0,09231346 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04861228 0,09224066 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04861228 0,09216797 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04861228 0,0920954 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04861228 0,09202294 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04861228 0,09195059 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04861228 0,09187836 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04861228 0,09180624 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04861228 0,09173424 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04861228 0,09166235 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04861228 0,09159057 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04861228 0,0915189 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,04898614 0,09215062 ! muscle fiber development GO:0048747 112 57 1,000 0,04898614 0,09207863 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04898614 0,09200675 ! maintenance of location GO:0051235 118 57 1,000 0,04898614 0,09193498 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,0505336 0,09476526 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,0505336 0,09469146 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,05209851 0,09754787 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,05209851 0,09747202 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,05209851 0,09739628 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,05368061 0,10027604 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,05368061 0,10019825 ! kidney development GO:0001822 122 60 1,000 0,05368061 0,10012057 ! axon extension GO:0048675 15 9 0,000 0,05452113 0,10160948 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05452113 0,10153084 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05452113 0,10145231 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05452113 0,10137391 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05452113 0,10129563 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05452113 0,10121747 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05452113 0,10113943 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05452113 0,10106151 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05452113 0,10098371 ! phosphate transport GO:0006817 19 9 0,000 0,05452113 0,10090603 ! reproductive behavior GO:0019098 19 9 0,000 0,05452113 0,10082847 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05452113 0,10075103 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05452113 0,10067371 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05452113 0,1005965 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05452113 0,10051942 ! RNA methylation GO:0001510 15 9 0,000 0,05452113 0,10044245 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05452113 0,1003656 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05452113 0,10028887 ! artery development GO:0060840 24 9 0,000 0,05452113 0,10021225 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05452113 0,10013576 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05452113 0,10005938 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05452113 0,09998311 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05452113 0,09990696 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05452113 0,09983093 ! chemosensory behavior GO:0007635 20 9 0,000 0,05452113 0,09975501 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05452113 0,09967921 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05452113 0,09960352 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05452113 0,09952795 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05452113 0,0994525 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05452113 0,09937715 ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05452113 0,09930192 ! protein targeting to ER GO:0045047 22 9 0,000 0,05452113 0,09922681 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05452113 0,09915181 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05452113 0,09907692 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05452113 0,09900214 ! endosome organization GO:0007032 17 9 0,000 0,05452113 0,09892748 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05452113 0,09885293 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05452113 0,0987785 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05452113 0,09870417 ! mannose metabolic process GO:0006013 13 9 0,000 0,05452113 0,09862996 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05452113 0,09855585 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05452113 0,09848186 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05452113 0,09840798 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05452113 0,09833421 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05452113 0,09826056 ! ruffle organization GO:0031529 15 9 0,000 0,05452113 0,09818701 ! retinol metabolic process GO:0042572 18 9 0,000 0,05452113 0,09811357 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05452113 0,09804024 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05452113 0,09796702 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05452113 0,09789391 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05452113 0,09782091 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05452113 0,09774802 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05452113 0,09767524 ! segment specification GO:0007379 13 9 0,000 0,05452113 0,09760256 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05452113 0,09752999 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05452113 0,09745753 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05452113 0,09738518 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05452113 0,09731294 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05452113 0,0972408 ! erythrocyte development GO:0048821 15 9 0,000 0,05452113 0,09716877 ! gas homeostasis GO:0033483 16 9 0,000 0,05452113 0,09709685 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05452113 0,09702503 ! renal water homeostasis GO:0003091 14 9 0,000 0,05452113 0,09695332 ! postreplication repair GO:0006301 22 9 0,000 0,05452113 0,09688171 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05452113 0,09681022 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05452113 0,09673882 ! icosanoid secretion GO:0032309 15 9 0,000 0,05452113 0,09666753 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05452113 0,09659635 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05452113 0,09652527 ! regulation of cell division GO:0051302 15 9 0,000 0,05452113 0,0964543 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05452113 0,09638343 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05452113 0,09631266 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05452113 0,096242 ! sterol catabolic process GO:0016127 11 9 0,000 0,05452113 0,09617144 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05452113 0,09610098 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05452113 0,09603063 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05452113 0,09596038 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05452113 0,09589024 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05452113 0,09582019 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05452113 0,09575025 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05452113 0,09568041 ! purine base metabolic process GO:0006144 21 9 0,000 0,05452113 0,09561067 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05452113 0,09554104 ! pigment granule transport GO:0051904 17 9 0,000 0,05452113 0,0954715 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05452113 0,09540207 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05452113 0,09533273 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05452113 0,0952635 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05452113 0,09519437 ! mitochondrion localization GO:0051646 15 9 0,000 0,05452113 0,09512534 ! viral reproductive process GO:0022415 126 62 1,000 0,05689527 0,09919567 ! gonad development GO:0008406 98 62 1,000 0,05689527 0,09912384 ! detection of external stimulus GO:0009581 91 63 1,000 0,0585273 0,10189341 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,0585273 0,10181973 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,06017545 0,10461137 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06039348 0,10491459 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06039348 0,10483889 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06039348 0,1047633 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06039348 0,10468783 ! synapsis GO:0007129 13 10 0,000 0,06039348 0,10461246 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06039348 0,1045372 ! N-glycan processing GO:0006491 20 10 0,000 0,06039348 0,10446204 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06039348 0,104387 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06039348 0,10431206 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06039348 0,10423723 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06039348 0,10416251 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06039348 0,1040879 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06039348 0,10401339 ! androgen metabolic process GO:0008209 17 10 0,000 0,06039348 0,10393899 ! phospholipid efflux GO:0033700 16 10 0,000 0,06039348 0,10386469 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06039348 0,1037905 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06039348 0,10371642 ! lung alveolus development GO:0048286 26 10 0,000 0,06039348 0,10364244 ! pathogenesis GO:0009405 13 10 0,000 0,06039348 0,10356857 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06039348 0,1034948 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06039348 0,10342114 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,06039348 0,10334758 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06039348 0,10327413 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06039348 0,10320078 ! endoderm development GO:0007492 16 10 0,000 0,06039348 0,10312754 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06039348 0,1030544 ! arginine catabolic process GO:0006527 13 10 0,000 0,06039348 0,10298136 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06039348 0,10290843 ! proline metabolic process GO:0006560 13 10 0,000 0,06039348 0,1028356 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06039348 0,10276287 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06039348 0,10269025 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06039348 0,10261773 ! V(D)J recombination GO:0033151 28 10 0,000 0,06039348 0,10254531 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06039348 0,10247299 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06039348 0,10240078 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06039348 0,10232866 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06039348 0,10225665 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06039348 0,10218474 ! multicellular organism growth GO:0035264 18 10 0,000 0,06039348 0,10211293 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06039348 0,10204122 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06039348 0,10196962 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06039348 0,10189811 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06039348 0,1018267 ! macroautophagy GO:0016236 17 10 0,000 0,06039348 0,10175539 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06039348 0,10168419 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06039348 0,10161308 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06039348 0,10154207 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06039348 0,10147116 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,06039348 0,10140035 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06039348 0,10132964 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06039348 0,10125903 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06039348 0,10118851 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06039348 0,1011181 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06039348 0,10104778 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06039348 0,10097756 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06039348 0,10090743 ! response to dsRNA GO:0043331 20 10 0,000 0,06039348 0,10083741 ! DNA ligation GO:0006266 19 10 0,000 0,06039348 0,10076748 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06039348 0,10069765 ! melanosome localization GO:0032400 16 10 0,000 0,06039348 0,10062791 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06039348 0,10055827 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06039348 0,10048873 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06039348 0,10041928 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06039348 0,10034993 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06039348 0,10028068 ! mRNA cleavage GO:0006379 17 10 0,000 0,06039348 0,10021152 ! protein sumoylation GO:0016925 15 10 0,000 0,06039348 0,10014246 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06039348 0,10007349 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06039348 0,10000461 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06039348 0,09993583 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06039348 0,09986715 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06039348 0,09979856 ! salivary gland development GO:0007431 27 10 0,000 0,06039348 0,09973006 ! prophase GO:0051324 15 10 0,000 0,06039348 0,09966166 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06039348 0,09959335 ! apical protein localization GO:0045176 15 10 0,000 0,06039348 0,09952514 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06039348 0,09945702 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06039348 0,09938899 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,06039348 0,09932105 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06039348 0,09925321 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06039348 0,09918546 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06039348 0,09911781 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06039348 0,09905024 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06039348 0,09898277 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06039348 0,09891539 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06039348 0,0988481 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,06039348 0,0987809 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,06039348 0,09871379 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06039348 0,09864678 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06039348 0,09857985 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06039348 0,09851302 ! activation of innate immune response GO:0002218 12 10 0,000 0,06039348 0,09844628 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06039348 0,09837962 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06039348 0,09831306 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06039348 0,09824659 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06039348 0,0981802 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06039348 0,09811391 ! localization within membrane GO:0051668 20 10 0,000 0,06039348 0,09804771 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,06183945 0,10032753 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,06183945 0,10025992 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,06351905 0,10291369 ! extracellular matrix organization GO:0030198 133 66 1,000 0,06351905 0,10284444 ! secondary metabolic process GO:0019748 116 66 1,000 0,06351905 0,10277527 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06521399 0,10544681 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06622954 0,10701698 ! respiratory burst GO:0045730 17 11 0,000 0,06622954 0,10694515 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06622954 0,10687342 ! neuron fate specification GO:0048665 17 11 0,000 0,06622954 0,10680179 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06622954 0,10673026 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06622954 0,10665882 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06622954 0,10658748 ! thyroid gland development GO:0030878 26 11 0,000 0,06622954 0,10651623 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06622954 0,10644507 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06622954 0,10637402 ! T cell proliferation GO:0042098 26 11 0,000 0,06622954 0,10630305 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06622954 0,10623218 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06622954 0,10616141 ! bone resorption GO:0045453 16 11 0,000 0,06622954 0,10609073 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06622954 0,10602014 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06622954 0,10594965 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06622954 0,10587925 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06622954 0,10580895 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06622954 0,10573874 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06622954 0,10566862 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06622954 0,10559859 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06622954 0,10552866 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06622954 0,10545882 ! lipid digestion GO:0044241 18 11 0,000 0,06622954 0,10538907 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06622954 0,10531942 ! UV protection GO:0009650 19 11 0,000 0,06622954 0,10524985 ! adult heart development GO:0007512 14 11 0,000 0,06622954 0,10518038 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06622954 0,105111 ! temperature homeostasis GO:0001659 17 11 0,000 0,06622954 0,10504171 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06622954 0,10497251 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06622954 0,10490341 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06622954 0,10483439 ! regulation of organ growth GO:0046620 13 11 0,000 0,06622954 0,10476547 ! pigment granule localization GO:0051875 20 11 0,000 0,06622954 0,10469663 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06622954 0,10462789 ! vasoconstriction GO:0042310 18 11 0,000 0,06622954 0,10455924 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06622954 0,10449067 ! embryonic axis specification GO:0000578 18 11 0,000 0,06622954 0,1044222 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06622954 0,10435382 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06622954 0,10428552 GO:0016180|snRNA processing, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06622954 0,10421732 ! zymogen activation GO:0031638 15 11 0,000 0,06622954 0,1041492 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06622954 0,10408117 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06622954 0,10401323 ! nucleosome positioning GO:0016584 15 11 0,000 0,06622954 0,10394539 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06622954 0,10387762 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06622954 0,10380995 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06622954 0,10374237 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06622954 0,10367487 ! acid secretion GO:0046717 18 11 0,000 0,06622954 0,10360746 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06622954 0,10354014 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06622954 0,10347291 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06622954 0,10340576 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06622954 0,1033387 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06622954 0,10327173 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06622954 0,10320484 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06622954 0,10313804 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06622954 0,10307133 ! germ cell migration GO:0008354 25 11 0,000 0,06622954 0,1030047 ! embryonic gut development GO:0048566 15 11 0,000 0,06622954 0,10293816 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06622954 0,10287171 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06622954 0,10280534 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06622954 0,10273906 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06622954 0,10267286 ! defense response to fungus GO:0050832 13 11 0,000 0,06622954 0,10260675 ! lysogeny GO:0030069 21 11 0,000 0,06622954 0,10254072 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06622954 0,10247478 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06622954 0,10240892 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06622954 0,10234314 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06622954 0,10227746 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06622954 0,10221185 ! amino acid transport GO:0006865 125 68 1,000 0,06692402 0,10321742 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,06692402 0,1031513 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,06692402 0,10308526 ! regulation of lipase activity GO:0060191 130 68 1,000 0,06692402 0,10301931 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,06692402 0,10295344 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06864888 0,10553943 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06864888 0,10547203 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,06864888 0,10540473 ! appendage morphogenesis GO:0035107 135 70 1,000 0,07038833 0,10800659 GO:0035108|limb morphogenesis, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07202955 0,11045449 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07202955 0,11038414 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07202955 0,11031388 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,07202955 0,1102437 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07202955 0,11017362 ! virus-host interaction GO:0019048 29 12 0,000 0,07202955 0,11010362 ! cartilage condensation GO:0001502 20 12 0,000 0,07202955 0,11003371 ! mating GO:0007618 17 12 0,000 0,07202955 0,10996389 ! protein complex disassembly GO:0043241 27 12 0,000 0,07202955 0,10989416 GO:0043624|cellular protein complex disassembly, ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07202955 0,10982452 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07202955 0,10975497 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07202955 0,10968551 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07202955 0,10961613 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07202955 0,10954684 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07202955 0,10947764 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07202955 0,10940852 ! drug transport GO:0015893 16 12 0,000 0,07202955 0,10933949 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07202955 0,10927055 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07202955 0,1092017 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07202955 0,10913293 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07202955 0,10906425 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07202955 0,10899566 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07202955 0,10892715 ! forebrain cell migration GO:0021885 21 12 0,000 0,07202955 0,10885873 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07202955 0,10879039 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07202955 0,10872214 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07202955 0,10865398 ! monoamine transport GO:0015844 18 12 0,000 0,07202955 0,1085859 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07202955 0,10851791 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07202955 0,10845 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07202955 0,10838218 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07202955 0,10831444 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07202955 0,10824678 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07202955 0,10817921 ! protein homotetramerization GO:0051289 21 12 0,000 0,07202955 0,10811173 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07202955 0,10804433 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07202955 0,10797701 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07202955 0,10790977 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07202955 0,10784262 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07202955 0,10777556 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07202955 0,10770858 ! cranial nerve development GO:0021545 20 12 0,000 0,07202955 0,10764168 ! fucose catabolic process GO:0019317 22 12 0,000 0,07202955 0,10757486 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07202955 0,10750813 ! histone methylation GO:0016571 26 12 0,000 0,07202955 0,10744147 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07202955 0,10737491 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07202955 0,10730842 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07202955 0,10724202 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07202955 0,10717569 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07202955 0,10710945 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07202955 0,1070433 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07202955 0,10697722 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07202955 0,10691123 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,07202955 0,10684531 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07202955 0,10677948 ! response to cold GO:0009409 17 12 0,000 0,07202955 0,10671373 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07202955 0,10664806 ! amine catabolic process GO:0009310 117 71 1,000 0,07214213 0,10674906 ! appendage development GO:0048736 136 71 1,000 0,07214213 0,10668345 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,07214213 0,10661792 ! B cell activation GO:0042113 160 71 1,000 0,07214213 0,10655247 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,07391003 0,10909665 ! carbohydrate transport GO:0008643 110 72 1,000 0,07391003 0,10902976 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,07391003 0,10896295 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,07391003 0,10889623 ! axon guidance GO:0007411 139 73 1,000 0,07569179 0,11145316 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07779372 0,11447811 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07779372 0,11440813 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07779372 0,11433824 ! peroxisomal transport GO:0043574 24 13 0,000 0,07779372 0,11426844 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07779372 0,11419872 ! lipid localization GO:0010876 28 13 0,000 0,07779372 0,11412909 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07779372 0,11405954 ! organelle fusion GO:0048284 32 13 0,000 0,07779372 0,11399007 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07779372 0,11392069 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07779372 0,1138514 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07779372 0,11378219 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07779372 0,11371306 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07779372 0,11364402 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07779372 0,11357506 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07779372 0,11350619 ! methionine metabolic process GO:0006555 27 13 0,000 0,07779372 0,1134374 ! plasma membrane organization GO:0007009 24 13 0,000 0,07779372 0,11336869 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07779372 0,11330006 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07779372 0,11323152 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07779372 0,11316306 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07779372 0,11309468 ! response to X-ray GO:0010165 25 13 0,000 0,07779372 0,11302639 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07779372 0,11295818 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07779372 0,11289005 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07779372 0,112822 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07779372 0,11275404 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07779372 0,11268615 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07779372 0,11261835 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07779372 0,11255063 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07779372 0,11248299 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07779372 0,11241544 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07779372 0,11234796 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07779372 0,11228056 ! ribosome assembly GO:0042255 17 13 0,000 0,07779372 0,11221325 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07779372 0,11214602 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07779372 0,11207886 ! chromatin silencing GO:0006342 26 13 0,000 0,07779372 0,11201179 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07779372 0,1119448 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07779372 0,11187789 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07779372 0,11181105 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07779372 0,1117443 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07779372 0,11167763 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07779372 0,11161103 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07779372 0,11154452 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07779372 0,11147808 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07779372 0,11141173 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07779372 0,11134545 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07779372 0,11127925 ! insulin secretion GO:0030073 23 13 0,000 0,07779372 0,11121313 ! actin filament polymerization GO:0030041 24 13 0,000 0,07779372 0,11114709 ! acrosome reaction GO:0007340 18 13 0,000 0,07779372 0,11108113 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,07929595 0,11315899 ! rhythmic process GO:0048511 128 75 1,000 0,07929595 0,11309191 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,07929595 0,11302491 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,08295272 0,11816711 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,08295272 0,11809719 ! rRNA transcription GO:0009303 25 14 0,000 0,08352228 0,11883774 ! lactation GO:0007595 26 14 0,000 0,08352228 0,1187675 ! reproductive cellular process GO:0048610 20 14 0,000 0,08352228 0,11869735 ! tRNA modification GO:0006400 20 14 0,000 0,08352228 0,11862728 ! regulation of S phase GO:0033261 23 14 0,000 0,08352228 0,1185573 ! water transport GO:0006833 21 14 0,000 0,08352228 0,11848739 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08352228 0,11841757 ! non-recombinational repair GO:0000726 25 14 0,000 0,08352228 0,11834783 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08352228 0,11827817 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08352228 0,1182086 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08352228 0,1181391 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08352228 0,11806969 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08352228 0,11800036 ! palate development GO:0060021 31 14 0,000 0,08352228 0,11793111 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08352228 0,11786195 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,08352228 0,11779286 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08352228 0,11772385 ! arginine metabolic process GO:0006525 17 14 0,000 0,08352228 0,11765493 ! regulation of heart rate GO:0002027 24 14 0,000 0,08352228 0,11758608 ! organic alcohol transport GO:0015850 29 14 0,000 0,08352228 0,11751732 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08352228 0,11744864 ! embryo implantation GO:0007566 30 14 0,000 0,08352228 0,11738003 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08352228 0,11731151 ! L-amino acid transport GO:0015807 30 14 0,000 0,08352228 0,11724307 ! bone mineralization GO:0030282 17 14 0,000 0,08352228 0,1171747 ! stem cell development GO:0048864 43 14 0,000 0,08352228 0,11710642 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08352228 0,11703822 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08352228 0,11697009 ! cerebellum development GO:0021549 21 14 0,000 0,08352228 0,11690205 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08352228 0,11683408 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08352228 0,11676619 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08352228 0,11669838 ! cofactor transport GO:0051181 26 14 0,000 0,08352228 0,11663065 ! NADP metabolic process GO:0006739 24 14 0,000 0,08352228 0,116563 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,08352228 0,11649543 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08352228 0,11642794 ! intestinal absorption GO:0050892 25 14 0,000 0,08352228 0,11636052 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08352228 0,11629318 ! oxygen transport GO:0015671 21 14 0,000 0,08352228 0,11622592 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08352228 0,11615874 ! regulation of axon extension GO:0030516 37 14 0,000 0,08352228 0,11609163 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08352228 0,11602461 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,08480026 0,11773193 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,08480026 0,11766404 ! protein oligomerization GO:0051259 139 78 1,000 0,08480026 0,11759622 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,08666027 0,12010635 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,08853253 0,12263055 ! response to metal ion GO:0010038 140 80 1,000 0,08853253 0,12255999 ! muscle cell differentiation GO:0042692 159 80 1,000 0,08853253 0,12248951 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,08853253 0,12241912 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08921545 0,12329257 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08921545 0,1232218 ! superoxide anion generation GO:0042554 20 15 0,000 0,08921545 0,1231511 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08921545 0,12308049 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08921545 0,12300995 ! copper ion transport GO:0006825 20 15 0,000 0,08921545 0,1229395 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08921545 0,12286913 ! sulfate transport GO:0008272 23 15 0,000 0,08921545 0,12279884 ! response to cAMP GO:0051591 22 15 0,000 0,08921545 0,12272863 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08921545 0,1226585 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08921545 0,12258845 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08921545 0,12251848 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08921545 0,12244859 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08921545 0,12237878 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08921545 0,12230904 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08921545 0,12223939 ! pituitary gland development GO:0021983 29 15 0,000 0,08921545 0,12216982 ! vesicle coating GO:0006901 33 15 0,000 0,08921545 0,12210033 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08921545 0,12203091 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08921545 0,12196157 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08921545 0,12189232 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08921545 0,12182314 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08921545 0,12175404 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08921545 0,12168502 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08921545 0,12161607 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08921545 0,12154721 ! histone deacetylation GO:0016575 20 15 0,000 0,08921545 0,12147842 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08921545 0,12140971 ! tissue regeneration GO:0042246 26 15 0,000 0,08921545 0,12134108 ! water homeostasis GO:0030104 27 15 0,000 0,08921545 0,12127253 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08921545 0,12120405 ! muscle maintenance GO:0046716 26 15 0,000 0,08921545 0,12113565 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08921545 0,12106733 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08921545 0,12099908 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08921545 0,12093091 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08921545 0,12086282 ! cell killing GO:0001906 29 15 0,000 0,08921545 0,12079481 ! detection of bacterium GO:0016045 18 15 0,000 0,08921545 0,12072687 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08921545 0,12065901 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08921545 0,12059122 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08921545 0,12052351 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08921545 0,12045588 ! peptide hormone processing GO:0016486 23 15 0,000 0,08921545 0,12038832 ! T cell activation GO:0042110 168 81 1,000 0,0904168 0,12194105 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,0904168 0,12187273 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,09231288 0,12435879 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,09231288 0,1242892 ! regulation of lyase activity GO:0051339 160 83 1,000 0,09422055 0,12678671 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,09487344 0,1275939 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09487344 0,12752262 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09487344 0,12745142 ! bone remodeling GO:0046849 27 16 0,000 0,09487344 0,12738029 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,09487344 0,12730925 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09487344 0,12723829 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09487344 0,1271674 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09487344 0,1270966 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09487344 0,12702587 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09487344 0,12695522 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09487344 0,12688465 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09487344 0,12681416 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09487344 0,12674375 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09487344 0,12667341 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09487344 0,12660315 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09487344 0,12653298 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09487344 0,12646287 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09487344 0,12639285 ! response to osmotic stress GO:0006970 25 16 0,000 0,09487344 0,1263229 ! lysosomal transport GO:0007041 26 16 0,000 0,09487344 0,12625303 ! fructose metabolic process GO:0006000 25 16 0,000 0,09487344 0,12618324 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09487344 0,12611353 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,09487344 0,12604389 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09487344 0,12597433 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09487344 0,12590485 ! axon cargo transport GO:0008088 43 16 0,000 0,09487344 0,12583544 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09487344 0,12576611 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09487344 0,12569685 ! DNA replication initiation GO:0006270 27 16 0,000 0,09487344 0,12562768 ! neuron recognition GO:0008038 35 16 0,000 0,09487344 0,12555857 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09487344 0,12548955 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09487344 0,1254206 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09487344 0,12535172 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09487344 0,12528292 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09487344 0,1252142 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09487344 0,12514555 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09487344 0,12507698 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09487344 0,12500848 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09487344 0,12494006 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09487344 0,12487171 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09487344 0,12480344 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,09613958 0,12639991 ! nucleosome assembly GO:0006334 122 85 1,000 0,09806977 0,12886722 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,09806977 0,12879687 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,10001091 0,13127455 ! chromatin assembly GO:0031497 124 86 1,000 0,10001091 0,13120297 ! amine transport GO:0015837 155 86 1,000 0,10001091 0,13113147 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,10049646 0,13169634 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,10049646 0,13162465 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10049646 0,13155304 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10049646 0,1314815 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10049646 0,13141005 ! endothelial cell migration GO:0043542 28 17 0,000 0,10049646 0,13133867 ! inositol metabolic process GO:0006020 28 17 0,000 0,10049646 0,13126736 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10049646 0,13119614 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10049646 0,13112499 ! glial cell development GO:0021782 27 17 0,000 0,10049646 0,13105392 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10049646 0,13098293 ! adult walking behavior GO:0007628 33 17 0,000 0,10049646 0,13091201 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10049646 0,13084117 ! heart looping GO:0001947 30 17 0,000 0,10049646 0,13077041 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,10049646 0,13069972 ! myoblast differentiation GO:0045445 45 17 0,000 0,10049646 0,13062911 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,10049646 0,13055858 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,10049646 0,13048812 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10049646 0,13041774 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,10049646 0,13034743 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,10049646 0,1302772 ! NAD metabolic process GO:0019674 29 17 0,000 0,10049646 0,13020705 ! membrane budding GO:0006900 37 17 0,000 0,10049646 0,13013697 ! DNA integration GO:0015074 29 17 0,000 0,10049646 0,13006696 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10049646 0,12999703 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10049646 0,12992718 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,10049646 0,1298574 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10049646 0,1297877 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,10049646 0,12971807 ! steroid catabolic process GO:0006706 31 17 0,000 0,10049646 0,12964852 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,10049646 0,12957904 ! gas transport GO:0015669 25 17 0,000 0,10049646 0,12950963 ! organic cation transport GO:0015695 31 17 0,000 0,10049646 0,1294403 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,10049646 0,12937105 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,10049646 0,12930186 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,10196279 0,13111837 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,10196279 0,13104833 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10608474 0,13627329 ! neuron maturation GO:0042551 42 18 0,000 0,10608474 0,13620058 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,10608474 0,13612794 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,10608474 0,13605537 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,10608474 0,13598289 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,10608474 0,13591048 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10608474 0,13583815 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10608474 0,13576589 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10608474 0,13569372 ! patterning of blood vessels GO:0001569 39 18 0,000 0,10608474 0,13562162 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10608474 0,13554959 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,10608474 0,13547764 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,10608474 0,13540577 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10608474 0,13533398 ! response to retinoic acid GO:0032526 26 18 0,000 0,10608474 0,13526226 ! response to fungus GO:0009620 21 18 0,000 0,10608474 0,13519061 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,10608474 0,13511905 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,10608474 0,13504756 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,10608474 0,13497614 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10608474 0,1349048 ! vitamin transport GO:0051180 27 18 0,000 0,10608474 0,13483353 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,10608474 0,13476234 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10608474 0,13469123 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10608474 0,13462019 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10608474 0,13454923 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,10608474 0,13447834 ! nerve development GO:0021675 28 18 0,000 0,10608474 0,13440752 ! ossification GO:0001503 188 90 1,000 0,10788079 0,13661115 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,10788079 0,13653929 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,10788079 0,1364675 ! bone development GO:0060348 189 91 1,000 0,10987358 0,13891531 ! response to protein stimulus GO:0051789 149 91 1,000 0,10987358 0,13884235 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,10987358 0,13876947 ! protein secretion GO:0009306 39 19 0,000 0,11163848 0,14092455 ! positive regulation of translation GO:0045727 30 19 0,000 0,11163848 0,14085065 ! negative regulation of defense response GO:0031348 25 19 0,000 0,11163848 0,14077683 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,11163848 0,14070309 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,11163848 0,14062942 ! skin development GO:0043588 36 19 0,000 0,11163848 0,14055583 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11163848 0,14048232 ! bile acid metabolic process GO:0008206 29 19 0,000 0,11163848 0,14040888 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,11163848 0,14033552 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,11163848 0,14026224 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,11163848 0,14018903 ! heme metabolic process GO:0042168 36 19 0,000 0,11163848 0,14011591 ! plasma membrane fusion GO:0045026 28 19 0,000 0,11163848 0,14004285 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,11163848 0,13996987 ! peptide cross-linking GO:0018149 37 19 0,000 0,11163848 0,13989697 ! protein export from nucleus GO:0006611 36 19 0,000 0,11163848 0,13982415 ! heart process GO:0003015 30 19 0,000 0,11163848 0,1397514 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,11163848 0,13967873 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,11163848 0,13960613 ! cell-cell junction organization GO:0045216 35 19 0,000 0,11163848 0,13953361 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,11163848 0,13946116 ! cilium assembly GO:0042384 37 19 0,000 0,11163848 0,13938879 ! peptide hormone secretion GO:0030072 31 19 0,000 0,11163848 0,13931649 ! nucleosome organization GO:0034728 138 92 1,000 0,1118761 0,13954064 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,11388814 0,14197662 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,11388814 0,14190309 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,11388814 0,14182964 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11715791 0,14582614 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11715791 0,14575074 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11715791 0,14567541 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11715791 0,14560017 ! response to vitamin GO:0033273 31 20 0,000 0,11715791 0,145525 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11715791 0,14544991 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,11715791 0,1453749 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11715791 0,14529996 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11715791 0,1452251 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11715791 0,14515032 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,11715791 0,14507562 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11715791 0,14500099 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11715791 0,14492644 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11715791 0,14485196 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,11715791 0,14477757 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,11715791 0,14470325 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11715791 0,144629 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11715791 0,14455483 ! body fluid secretion GO:0007589 31 20 0,000 0,11715791 0,14448074 ! peptide secretion GO:0002790 35 20 0,000 0,11715791 0,14440672 ! stem cell differentiation GO:0048863 53 20 0,000 0,11715791 0,14433278 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11715791 0,14425892 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11715791 0,14418513 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11715791 0,14411141 ! sensory perception of pain GO:0019233 30 20 0,000 0,11715791 0,14403777 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11715791 0,14396421 ! diencephalon development GO:0021536 34 20 0,000 0,11715791 0,14389072 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11715791 0,14381731 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11715791 0,14374397 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11715791 0,1436707 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11715791 0,14359752 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11715791 0,1435244 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11715791 0,14345136 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11715791 0,14337839 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11715791 0,1433055 ! actin filament-based movement GO:0030048 43 20 0,000 0,11715791 0,14323268 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11715791 0,14315994 ! negative regulation of translation GO:0017148 29 20 0,000 0,11715791 0,14308727 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11715791 0,14301467 ! detection of stimulus GO:0051606 151 96 1,000 0,11997954 0,14638477 ! protein ubiquitination GO:0016567 217 97 1,000 0,12202779 0,14880835 ! hormone metabolic process GO:0042445 157 97 1,000 0,12202779 0,14873296 ! regulation of cell killing GO:0031341 42 21 0,000 0,12264322 0,14940739 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,12264322 0,14933177 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,12264322 0,14925624 ! hormone secretion GO:0046879 38 21 0,000 0,12264322 0,14918078 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,12264322 0,1491054 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,12264322 0,14903009 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12264322 0,14895486 ! axis specification GO:0009798 38 21 0,000 0,12264322 0,14887971 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12264322 0,14880463 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12264322 0,14872963 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,12264322 0,1486547 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,12264322 0,14857985 ! cytolysis GO:0019835 24 21 0,000 0,12264322 0,14850508 ! vasodilation GO:0042311 39 21 0,000 0,12264322 0,14843038 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12264322 0,14835575 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12264322 0,1482812 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12264322 0,14820672 ! collagen fibril organization GO:0030199 59 21 0,000 0,12264322 0,14813232 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12264322 0,148058 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,12264322 0,14798374 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,12264322 0,14790957 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12264322 0,14783546 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12264322 0,14776144 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,12264322 0,14768748 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12264322 0,1476136 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12264322 0,14753979 ! response to virus GO:0009615 160 98 1,000 0,12408463 0,14919921 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,12614986 0,15160668 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,12809463 0,15386704 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12809463 0,15379026 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12809463 0,15371356 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12809463 0,15363693 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12809463 0,15356038 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12809463 0,15348391 ! keratinization GO:0031424 28 22 0,000 0,12809463 0,15340751 ! sensory perception of taste GO:0050909 28 22 0,000 0,12809463 0,15333119 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12809463 0,15325494 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12809463 0,15317877 ! vacuolar transport GO:0007034 36 22 0,000 0,12809463 0,15310268 ! lysosome organization GO:0007040 41 22 0,000 0,12809463 0,15302666 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12809463 0,15295071 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12809463 0,15287484 ! fucose metabolic process GO:0006004 39 22 0,000 0,12809463 0,15279905 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12809463 0,15272333 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12809463 0,15264769 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12809463 0,15257212 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12809463 0,15249663 ! sarcomere organization GO:0045214 30 22 0,000 0,12809463 0,15242121 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12809463 0,15234587 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,13351235 0,15871083 ! viral genome replication GO:0019079 41 23 0,000 0,13351235 0,15863245 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13351235 0,15855416 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,13351235 0,15847594 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13351235 0,15839779 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13351235 0,15831972 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13351235 0,15824173 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,13351235 0,15816382 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,13351235 0,15808598 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13351235 0,15800822 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,13351235 0,15793054 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,13351235 0,15785293 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,13351235 0,1577754 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,13351235 0,15769795 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,13351235 0,15762057 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,13351235 0,15754327 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,13351235 0,15746604 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,13351235 0,15738889 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,13351235 0,15731181 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13351235 0,15723481 ! platelet activation GO:0030168 37 23 0,000 0,13351235 0,15715789 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,13351235 0,15708104 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,13351235 0,15700426 ! hormone transport GO:0009914 40 23 0,000 0,13351235 0,15692756 ! cell-cell recognition GO:0009988 25 23 0,000 0,13351235 0,15685094 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,13351235 0,15677439 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,13351235 0,15669791 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,13351235 0,15662151 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,13889659 0,16285828 ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,13889659 0,16277895 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13889659 0,1626997 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13889659 0,16262053 ! vesicle docking GO:0048278 47 24 0,000 0,13889659 0,16254144 ! spinal cord development GO:0021510 47 24 0,000 0,13889659 0,16246242 ! vacuole organization GO:0007033 43 24 0,000 0,13889659 0,16238348 ! digestive system process GO:0022600 39 24 0,000 0,13889659 0,16230461 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13889659 0,16222582 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13889659 0,16214711 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13889659 0,16206847 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13889659 0,16198991 ! pentose metabolic process GO:0019321 35 24 0,000 0,13889659 0,16191143 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13889659 0,16183302 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13889659 0,16175469 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13889659 0,16167644 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13889659 0,16159826 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13889659 0,16152015 ! regulation of amine transport GO:0051952 40 24 0,000 0,13889659 0,16144212 ! protein tetramerization GO:0051262 52 24 0,000 0,13889659 0,16136417 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14424755 0,1674998 ! phototransduction GO:0007602 33 25 0,000 0,14424755 0,167419 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14424755 0,16733828 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,14424755 0,16725764 ! sperm motility GO:0030317 31 25 0,000 0,14424755 0,16717707 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14424755 0,16709658 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,14424755 0,16701617 ! chromosome condensation GO:0030261 45 25 0,000 0,14424755 0,16693583 ! response to starvation GO:0042594 42 25 0,000 0,14424755 0,16685557 ! osteoblast differentiation GO:0001649 60 25 0,000 0,14424755 0,16677539 ! neural crest cell development GO:0014032 54 25 0,000 0,14424755 0,16669529 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,14424755 0,16661526 ! negative regulation of cell development GO:0010721 73 25 0,000 0,14424755 0,16653531 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14424755 0,16645544 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,14424755 0,16637564 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,14424755 0,16629592 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14424755 0,16621628 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14424755 0,16613671 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14424755 0,16605722 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,14424755 0,16597781 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,14424755 0,16589847 ! telomere organization GO:0032200 43 25 0,000 0,14424755 0,1658192 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,14424755 0,16574002 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,14424755 0,1656609 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14956543 0,17168627 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14956543 0,1716044 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14956543 0,1715226 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14956543 0,17144089 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14956543 0,17135925 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14956543 0,17127769 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14956543 0,1711962 ! tube lumen formation GO:0035148 50 26 0,000 0,14956543 0,1711148 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14956543 0,17103347 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14956543 0,17095222 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,14956543 0,17087104 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14956543 0,17078995 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14956543 0,17070893 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14956543 0,17062798 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14956543 0,17054712 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14956543 0,17046633 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14956543 0,17038561 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14956543 0,17030498 ! neuron fate commitment GO:0048663 48 27 0,000 0,15485044 0,17623943 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,15485044 0,1761561 ! iron ion transport GO:0006826 59 27 0,000 0,15485044 0,17607285 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,15485044 0,17598968 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,15485044 0,17590659 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,15485044 0,17582357 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,15485044 0,17574064 ! autophagy GO:0006914 41 27 0,000 0,15485044 0,17565778 ! primary neural tube formation GO:0014020 51 27 0,000 0,15485044 0,175575 ! base-excision repair GO:0006284 41 27 0,000 0,15485044 0,1754923 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,15485044 0,17540968 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,15485044 0,17532713 ! glutathione metabolic process GO:0006749 39 27 0,000 0,15485044 0,17524466 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,15485044 0,17516227 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,15485044 0,17507996 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,15485044 0,17499772 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,16010278 0,18084849 ! circadian rhythm GO:0007623 50 28 0,000 0,16010278 0,18076363 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,16010278 0,18067884 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,16010278 0,18059413 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,16010278 0,18050951 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,16010278 0,18042496 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,16010278 0,18034049 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,16010278 0,1802561 ! synaptogenesis GO:0007416 42 28 0,000 0,16010278 0,18017179 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,16010278 0,18008756 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,16010278 0,18000341 ! translational initiation GO:0006413 65 29 0,000 0,16532265 0,18578529 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,16532265 0,18569856 ! regulation of pH GO:0006885 43 29 0,000 0,16532265 0,1856119 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,16532265 0,18552533 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,16532265 0,18543884 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,16532265 0,18535243 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,16532265 0,18526609 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,16532265 0,18517984 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,16532265 0,18509367 ! cell fate determination GO:0001709 60 29 0,000 0,16532265 0,18500758 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,16532265 0,18492157 ! detection of light stimulus GO:0009583 38 29 0,000 0,16532265 0,18483564 ! zinc ion transport GO:0006829 45 30 0,000 0,17051026 0,190547 ! membrane docking GO:0022406 61 30 0,000 0,17051026 0,19045853 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,17051026 0,19037015 ! regulation of innate immune response GO:0045088 51 30 0,000 0,17051026 0,19028186 ! acute-phase response GO:0006953 49 30 0,000 0,17051026 0,19019364 ! myofibril assembly GO:0030239 47 30 0,000 0,17051026 0,19010551 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,17051026 0,19001745 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,17051026 0,18992948 ! phospholipid transport GO:0015914 51 30 0,000 0,17051026 0,18984159 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,17051026 0,18975379 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,17051026 0,18966606 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,17051026 0,18957841 ! eye morphogenesis GO:0048592 60 30 0,000 0,17051026 0,18949085 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,17566579 0,19513015 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,17566579 0,1950401 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,17566579 0,19495014 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,17566579 0,19486026 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,17566579 0,19477046 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,17566579 0,19468075 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,17566579 0,19459111 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,17566579 0,19450157 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,17566579 0,1944121 ! peptide transport GO:0015833 55 31 0,000 0,17566579 0,19432271 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,17566579 0,19423341 ! mesoderm formation GO:0001707 69 31 0,000 0,17566579 0,19414419 ! natural killer cell activation GO:0030101 45 31 0,000 0,17566579 0,19405505 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,17566579 0,19396599 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,17566579 0,19387702 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,18078946 0,19944036 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,18078946 0,19934896 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,18078946 0,19925764 ! cholesterol transport GO:0030301 56 32 0,000 0,18078946 0,19916641 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,18078946 0,19907525 ! spliceosome assembly GO:0000245 67 32 0,000 0,18078946 0,19898419 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,18078946 0,1988932 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,18078946 0,1988023 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,18078946 0,19871148 ! muscle cell development GO:0055001 49 32 0,000 0,18078946 0,19862075 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,18078946 0,19853009 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,18078946 0,19843952 ! BMP signaling pathway GO:0030509 64 32 0,000 0,18078946 0,19834903 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,18078946 0,19825863 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,18078946 0,19816831 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,18078946 0,19807807 ! gene silencing GO:0016458 65 32 0,000 0,18078946 0,19798791 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,18588144 0,20347168 ! protein targeting to membrane GO:0006612 68 33 0,000 0,18588144 0,20337915 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,18588144 0,2032867 ! ceramide metabolic process GO:0006672 64 33 0,000 0,18588144 0,20319434 ! formation of primary germ layer GO:0001704 72 33 0,000 0,18588144 0,20310207 ! sterol transport GO:0015918 57 33 0,000 0,18588144 0,20300987 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,18588144 0,20291776 ! adult locomotory behavior GO:0008344 59 33 0,000 0,18588144 0,20282574 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,18588144 0,20273379 ! glial cell differentiation GO:0010001 63 34 0,000 0,19094194 0,20815873 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,19094194 0,20806446 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,19094194 0,20797027 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,19094194 0,20787616 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,19094194 0,20778214 ! spermatid development GO:0007286 63 34 0,000 0,19094194 0,20768821 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,19094194 0,20759436 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,19597116 0,21296595 ! negative regulation of secretion GO:0051048 63 35 0,000 0,19597116 0,2128698 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,19597116 0,21277374 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,19597116 0,21267777 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,19597116 0,21258188 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,19597116 0,21248608 ! cytokine production GO:0001816 59 35 0,000 0,19597116 0,21239036 ! neural tube formation GO:0001841 67 35 0,000 0,19597116 0,21229474 ! vesicle localization GO:0051648 64 35 0,000 0,19597116 0,21219919 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,20096928 0,21751331 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,20096928 0,2174155 ! regulation of proteolysis GO:0030162 72 36 0,000 0,20096928 0,21731779 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,20096928 0,21722016 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,20096928 0,21712262 ! aerobic respiration GO:0009060 55 36 0,000 0,20096928 0,21702517 ! embryonic organ development GO:0048568 57 36 0,000 0,20096928 0,21692781 ! RNA export from nucleus GO:0006405 56 37 0,000 0,20593649 0,22218977 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,20593649 0,22209018 ! actomyosin structure organization GO:0031032 62 37 0,000 0,20593649 0,22199068 ! organic anion transport GO:0015711 68 37 0,000 0,20593649 0,22189127 ! tissue remodeling GO:0048771 76 37 0,000 0,20593649 0,22179194 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,20593649 0,2216927 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,20593649 0,22159356 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,20593649 0,2214945 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,20593649 0,22139553 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,20593649 0,22129665 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,21087299 0,22650018 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,21087299 0,22639911 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,21087299 0,22629813 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,21087299 0,22619724 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,21087299 0,22609644 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,21087299 0,22599573 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,21087299 0,22589511 ! mRNA catabolic process GO:0006402 71 39 0,000 0,21577896 0,2310477 ! organic ether metabolic process GO:0018904 55 39 0,000 0,21577896 0,23094492 ! ion transmembrane transport GO:0034220 66 39 0,000 0,21577896 0,23084223 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,21577896 0,23073964 ! RNA modification GO:0009451 57 39 0,000 0,21577896 0,23063713 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,21577896 0,23053472 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,2206546 0,23563913 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,2206546 0,23553459 ! feeding behavior GO:0007631 59 40 0,000 0,2206546 0,23543014 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,2206546 0,23532578 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,22550008 0,24038688 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,22550008 0,24028042 ! gliogenesis GO:0042063 88 41 0,000 0,22550008 0,24017405 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,22550008 0,24006778 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,22550008 0,23996161 ! regulation of tube size GO:0035150 71 42 0,000 0,2303156 0,2449776 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,2303156 0,24486934 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,2303156 0,24476119 ! regulation of protein secretion GO:0050708 71 42 0,000 0,2303156 0,24465312 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,23510133 0,24962657 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,23510133 0,24951645 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,23510133 0,24940644 ! striated muscle contraction GO:0006941 77 43 0,000 0,23510133 0,24929652 ! phagocytosis GO:0006909 90 43 0,000 0,23510133 0,2491867 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23985747 0,25411584 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,23985747 0,25400399 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23985747 0,25389224 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,24458419 0,25878169 ! glycolysis GO:0006096 65 45 0,000 0,24458419 0,25866794 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,24458419 0,25855429 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,24458419 0,25844074 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,24458419 0,25832728 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,24458419 0,25821393 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,24928167 0,26305776 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,24928167 0,26294244 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,24928167 0,26282721 ! response to calcium ion GO:0051592 81 47 0,000 0,2539501 0,26763204 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,2539501 0,26751486 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,2539501 0,26739779 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,2539501 0,26728082 ! JNK cascade GO:0007254 91 47 0,000 0,2539501 0,26716395 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,2539501 0,26704718 ! Notch signaling pathway GO:0007219 96 48 0,000 0,25858965 0,27180721 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,25858965 0,27168852 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,25858965 0,27156993 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,25858965 0,27145144 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,25858965 0,27133306 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,26320051 0,27605075 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,26320051 0,27593047 ! regulation of ion transport GO:0043269 77 49 0,000 0,26320051 0,27581029 ! peptide metabolic process GO:0006518 76 49 0,000 0,26320051 0,27569021 ! endocrine system development GO:0035270 104 49 0,000 0,26320051 0,27557024 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,26320051 0,27545038 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,26320051 0,27533062 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,26320051 0,27521096 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,26778284 0,27988076 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,27233682 0,28451689 ! excretion GO:0007588 83 51 0,000 0,27233682 0,2843934 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,27233682 0,28427002 ! chromatin remodeling GO:0006338 109 51 0,000 0,27233682 0,28414674 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,27233682 0,28402357 ! regulation of cell shape GO:0008360 125 51 0,000 0,27233682 0,28390051 ! amino acid activation GO:0043038 92 52 0,000 0,27686263 0,2884935 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,28136044 0,29305334 ! RNA catabolic process GO:0006401 93 53 0,000 0,28136044 0,29292653 ! regulation of translational initiation GO:0006446 82 53 0,000 0,28136044 0,29279984 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,28136044 0,29267325 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,28136044 0,29254677 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,28136044 0,2924204 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,28136044 0,29229414 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,28583042 0,29680967 ! cell recognition GO:0008037 85 54 0,000 0,28583042 0,29668162 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,28583042 0,29655369 ! chloride transport GO:0006821 90 55 0,000 0,29027275 0,30103286 ! glucose catabolic process GO:0006007 82 55 0,000 0,29027275 0,30090316 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,29027275 0,30077358 ! gastrulation GO:0007369 112 55 0,000 0,29027275 0,3006441 ! heart morphogenesis GO:0003007 97 55 0,000 0,29027275 0,30051473 ! RNA elongation GO:0006354 79 55 0,000 0,29027275 0,30038548 ! nuclear export GO:0051168 97 55 0,000 0,29027275 0,30025634 ! regulation of actin filament length GO:0030832 105 56 0,000 0,2946876 0,30469203 ! sensory perception of smell GO:0007608 80 56 0,000 0,2946876 0,30456115 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,2946876 0,30443038 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,2946876 0,30429972 ! proton transport GO:0015992 94 56 0,000 0,2946876 0,30416918 ! hydrogen transport GO:0006818 97 58 0,000 0,3034355 0,31306424 ! regulation of endocytosis GO:0030100 91 58 0,000 0,3034355 0,31293005 ! adult behavior GO:0030534 99 58 0,000 0,3034355 0,31279598 ! positive regulation of secretion GO:0051047 95 59 0,000 0,3077689 0,31712718 ! regulation of cellular component size GO:0032535 109 59 0,000 0,3077689 0,31699142 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,3077689 0,31685578 GO:0032313|regulation of Rab GTPase activity, ! nucleoside metabolic process GO:0009116 81 60 0,000 0,31207548 0,32115209 ! camera-type eye development GO:0043010 116 60 0,000 0,31207548 0,32101479 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,31635541 0,32527825 ! mesoderm development GO:0007498 119 61 0,000 0,31635541 0,3251393 ! tRNA processing GO:0008033 89 61 0,000 0,31635541 0,32500047 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,31635541 0,32486176 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,32060885 0,32908912 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,32483597 0,33328587 ! cell redox homeostasis GO:0045454 102 64 0,000 0,32903693 0,3374522 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,32903693 0,33730842 ! single fertilization GO:0007338 75 64 0,000 0,32903693 0,33716476 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,3332119 0,3412975 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,3332119 0,34115226 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,33736102 0,34525334 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,34148446 0,34932466 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,34148446 0,3491762 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,34148446 0,34902787 ! hexose catabolic process GO:0019320 104 67 0,000 0,34148446 0,34887966 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,34148446 0,34873158 ! adaptive immune response GO:0002250 119 67 0,000 0,34148446 0,34858362 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,34148446 0,34843579 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,34558237 0,35246765 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,34558237 0,3523183 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,34965492 0,35631925 ! antigen processing and presentation GO:0019882 104 69 0,000 0,34965492 0,35616839 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,35772455 0,36423414 ! regulation of immune effector process GO:0002697 137 71 0,000 0,35772455 0,36408007 ! acute inflammatory response GO:0002526 113 72 0,000 0,36172194 0,36799281 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,36569458 0,37187708 ! fertilization GO:0009566 90 73 0,000 0,36569458 0,37171997 ! transition metal ion transport GO:0000041 126 74 0,000 0,36964263 0,37557439 ! neurotransmitter transport GO:0006836 123 74 0,000 0,36964263 0,37541586 ! exocytosis GO:0006887 133 74 0,000 0,36964263 0,37525745 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,36964263 0,37509918 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,36964263 0,37494105 ! eye development GO:0001654 143 74 0,000 0,36964263 0,37478305 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,37356623 0,37860167 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,37746554 0,38239246 ! defense response to bacterium GO:0042742 89 76 0,000 0,37746554 0,38223152 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,37746554 0,38207072 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,37746554 0,38191005 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,38134071 0,38566867 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,38134071 0,38550662 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,38901922 0,39310384 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,38901922 0,39293881 ! protein import into nucleus GO:0006606 158 80 0,000 0,39282285 0,39661425 ! inorganic anion transport GO:0015698 138 80 0,000 0,39282285 0,39644789 ! digestion GO:0007586 112 81 0,000 0,39660292 0,40009502 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,39660292 0,39992734 ! nuclear import GO:0051170 161 81 0,000 0,39660292 0,39975979 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,40035959 0,40337737 ! response to unfolded protein GO:0006986 131 85 0,000 0,41149058 0,41441872 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,41515504 0,41793432 ! alcohol catabolic process GO:0046164 130 86 0,000 0,41515504 0,41775953 ! protein localization in nucleus GO:0034504 176 87 0,000 0,41879681 0,42124797 ! cellular respiration GO:0045333 135 88 0,000 0,42241603 0,42471081 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,42241603 0,4245334 ! cellular defense response GO:0006968 114 89 0,000 0,42601282 0,42796946 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,42601282 0,42779084 ! sterol metabolic process GO:0016125 152 91 0,000 0,43313972 0,43476602 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,43667009 0,43812687 ! vitamin metabolic process GO:0006766 139 92 0,000 0,43667009 0,43794424 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,44713051 0,44824834 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,45057421 0,45151251 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,45057421 0,45132454 ! positive regulation of immune response GO:0050778 156 96 0,000 0,45057421 0,45113672 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,45399656 0,45437427 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,45739772 0,4575879 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,4607778 0,4607778