pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6608-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! urogenital system development GO:0001655 101 61 7,000 1,498E-08 3,446E-05 ! positive regulation of inflammatory response GO:0050729 30 20 4,000 2,871E-07 3,302E-04 ! branching morphogenesis of a tube GO:0048754 72 42 5,000 6,06E-07 4,646E-04 ! negative regulation of phosphorylation GO:0042326 41 23 4,000 6,121E-07 3,52E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 5,000 7E-07 3,22E-04 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 4,000 9,551E-07 3,661E-04 GO:0045936|negative regulation of phosphate metabolic process, ! morphogenesis of a branching structure GO:0001763 86 49 5,000 1,549E-06 5,088E-04 ! cartilage development GO:0051216 70 49 5,000 1,549E-06 4,452E-04 ! gland development GO:0048732 148 77 6,000 1,584E-06 4,048E-04 ! regulation of cell cycle process GO:0010564 122 81 6,000 2,235E-06 5,14E-04 ! kidney development GO:0001822 90 53 5,000 2,482E-06 5,189E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 3,000 2,675E-06 5,127E-04 GO:0060675|ureteric bud morphogenesis, ! metanephros development GO:0001656 58 31 4,000 2,948E-06 5,216E-04 ! mitotic sister chromatid segregation GO:0000070 45 32 4,000 3,473E-06 5,706E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 5,000 3,829E-06 5,872E-04 ! sister chromatid segregation GO:0000819 46 33 4,000 4,07E-06 5,85E-04 ! negative regulation of kinase activity GO:0033673 100 58 5,000 4,246E-06 5,744E-04 ! neutrophil chemotaxis GO:0030593 21 16 3,000 4,808E-06 6,143E-04 ! negative regulation of translation GO:0017148 22 16 3,000 4,808E-06 5,82E-04 ! negative regulation of transferase activity GO:0051348 105 61 5,000 5,72E-06 6,578E-04 ! prostate gland development GO:0030850 9 6 2,000 7,725E-06 8,46E-04 ! apoptotic mitochondrial changes GO:0008637 29 18 3,000 7,992E-06 8,355E-04 ! pigmentation GO:0043473 74 38 4,000 8,356E-06 8,356E-04 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 6,000 8,573E-06 8,216E-04 ! positive regulation of response to external stimulus GO:0032103 65 40 4,000 1,083E-05 9,96E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 1,083E-05 9,577E-04 ! collagen fibril organization GO:0030199 45 20 3,000 1,251E-05 1,066E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 5,000 1,279E-05 1,051E-03 ! regulation of smooth muscle cell migration GO:0014910 19 7 2,000 1,344E-05 1,066E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 2,000 1,344E-05 1,031E-03 ! regulation of pigmentation during development GO:0048070 15 7 2,000 1,344E-05 9,975E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,344E-05 9,664E-04 ! phosphoinositide-mediated signaling GO:0048015 109 71 5,000 1,389E-05 9,682E-04 ! tube morphogenesis GO:0035239 118 73 5,000 1,631E-05 1,104E-03 ! regulation of inflammatory response GO:0050727 60 44 4,000 1,745E-05 1,147E-03 ! ureteric bud development GO:0001657 32 22 3,000 1,867E-05 1,193E-03 ! positive regulation of cell cycle GO:0045787 77 45 4,000 1,952E-05 1,213E-03 ! positive regulation of defense response GO:0031349 59 45 4,000 1,952E-05 1,181E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 2,14E-05 1,262E-03 ! induction of positive chemotaxis GO:0050930 14 8 2,000 2,14E-05 1,23E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 2,000 2,14E-05 1,2E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 2,14E-05 1,172E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,14E-05 1,144E-03 ! regulation of ossification GO:0030278 71 46 4,000 2,177E-05 1,138E-03 ! negative regulation of immune system process GO:0002683 73 47 4,000 2,422E-05 1,238E-03 ! insulin receptor signaling pathway GO:0008286 40 24 3,000 2,682E-05 1,341E-03 ! forebrain development GO:0030900 131 80 5,000 2,761E-05 1,351E-03 ! SMAD protein nuclear translocation GO:0007184 15 9 2,000 3,192E-05 1,53E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 3,192E-05 1,498E-03 ! negative regulation of BMP signaling pathway GO:0030514 13 9 2,000 3,192E-05 1,468E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 3,622E-05 1,633E-03 ! positive regulation of cell migration GO:0030335 92 51 4,000 3,622E-05 1,602E-03 ! aging GO:0007568 79 52 4,000 3,984E-05 1,729E-03 ! cell cycle arrest GO:0007050 150 86 5,000 4,167E-05 1,775E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 5,000 4,167E-05 1,743E-03 ! regulation of bone remodeling GO:0046850 90 53 4,000 4,373E-05 1,796E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 4,535E-05 1,83E-03 ! hair follicle morphogenesis GO:0031069 17 10 2,000 4,535E-05 1,799E-03 ! interphase GO:0051325 159 88 5,000 4,746E-05 1,85E-03 ! regulation of mitosis GO:0007088 84 54 4,000 4,791E-05 1,836E-03 GO:0051783|regulation of nuclear division, ! regulation of tissue remodeling GO:0034103 91 54 4,000 4,791E-05 1,806E-03 ! cell junction assembly GO:0034329 56 28 3,000 5,05E-05 1,873E-03 ! reproductive developmental process GO:0003006 127 89 5,000 5,058E-05 1,847E-03 ! positive regulation of cell motion GO:0051272 99 56 4,000 5,719E-05 2,055E-03 ! regulation of positive chemotaxis GO:0050926 17 11 2,000 6,203E-05 2,195E-03 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 2,000 6,203E-05 2,162E-03 ! focal adhesion formation GO:0048041 24 11 2,000 6,203E-05 2,129E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 6,203E-05 2,098E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 6,203E-05 2,068E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 6,203E-05 2,038E-03 GO:0042130|negative regulation of T cell proliferation, ! chromosome segregation GO:0007059 83 57 4,000 6,232E-05 2,019E-03 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 6,232E-05 1,991E-03 ! peptidyl-amino acid modification GO:0018193 147 93 5,000 6,477E-05 2,041E-03 ! spindle organization GO:0007051 37 30 3,000 6,683E-05 2,077E-03 ! leukocyte chemotaxis GO:0030595 43 31 3,000 7,629E-05 2,34E-03 GO:0060326|cell chemotaxis, ! gland morphogenesis GO:0022612 23 12 2,000 8,226E-05 2,489E-03 ! regulation of protein stability GO:0031647 48 32 3,000 8,669E-05 2,59E-03 ! negative regulation of cell growth GO:0030308 106 62 4,000 9,351E-05 2,757E-03 ! cell junction organization GO:0034330 63 33 3,000 9,809E-05 2,856E-03 ! positive regulation of cell development GO:0010720 54 33 3,000 9,809E-05 2,82E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 1,064E-04 3,02E-03 ! negative regulation of cell size GO:0045792 108 64 4,000 1,089E-04 3,054E-03 ! appendage morphogenesis GO:0035107 93 64 4,000 1,089E-04 3,017E-03 GO:0035108|limb morphogenesis, ! cellular response to insulin stimulus GO:0032869 52 34 3,000 1,105E-04 3,027E-03 ! reproductive structure development GO:0048608 90 65 4,000 1,173E-04 3,173E-03 ! appendage development GO:0048736 94 65 4,000 1,173E-04 3,136E-03 GO:0060173|limb development, ! epidermis morphogenesis GO:0048730 29 14 2,000 1,346E-04 3,559E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,346E-04 3,519E-03 ! epithelial to mesenchymal transition GO:0001837 22 14 2,000 1,346E-04 3,479E-03 ! negative regulation of cell cycle process GO:0010948 24 15 2,000 1,674E-04 4,278E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,674E-04 4,231E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 1,674E-04 4,185E-03 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 2,000 1,674E-04 4,14E-03 ! regulation of BMP signaling pathway GO:0030510 21 15 2,000 1,674E-04 4,096E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 1,674E-04 4,052E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! mesenchymal cell development GO:0014031 64 38 3,000 1,72E-04 4,12E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 1,905E-04 4,518E-03 ! multicellular organismal metabolic process GO:0044236 50 39 3,000 1,905E-04 4,472E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 2,000 2,049E-04 4,76E-03 ! cellular response to hormone stimulus GO:0032870 109 74 4,000 2,169E-04 4,989E-03 ! negative regulation of growth GO:0045926 123 75 4,000 2,311E-04 5,262E-03 ! regulation of T cell differentiation GO:0045580 59 41 3,000 2,319E-04 5,23E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 2,475E-04 5,526E-03 ! cell-substrate junction assembly GO:0007044 39 17 2,000 2,475E-04 5,473E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 2,475E-04 5,421E-03 ! peptidyl-serine modification GO:0018209 27 17 2,000 2,475E-04 5,37E-03 ! leukocyte migration GO:0050900 60 43 3,000 2,794E-04 6,007E-03 ! response to insulin stimulus GO:0032868 63 43 3,000 2,794E-04 5,951E-03 ! epithelial tube morphogenesis GO:0060562 65 43 3,000 2,794E-04 5,896E-03 ! positive regulation of DNA replication GO:0045740 29 18 2,000 2,954E-04 6,176E-03 ! pigmentation during development GO:0048066 31 18 2,000 2,954E-04 6,12E-03 ! central nervous system neuron development GO:0021954 30 18 2,000 2,954E-04 6,066E-03 ! regulation of glucose import GO:0046324 21 18 2,000 2,954E-04 6,012E-03 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 2,000 2,954E-04 5,959E-03 ! negative regulation of T cell activation GO:0050868 25 18 2,000 2,954E-04 5,907E-03 ! glycolysis GO:0006096 53 44 3,000 3,056E-04 6,06E-03 ! regulation of action potential GO:0001508 71 44 3,000 3,056E-04 6,008E-03 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 3,056E-04 5,957E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 3,336E-04 6,447E-03 ! positive regulation of ossification GO:0045778 30 19 2,000 3,489E-04 6,686E-03 ! response to alkaloid GO:0043279 32 19 2,000 3,489E-04 6,631E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 3,489E-04 6,577E-03 ! cell structure disassembly during apoptosis GO:0006921 24 19 2,000 3,489E-04 6,523E-03 ! apoptotic nuclear changes GO:0030262 24 19 2,000 3,489E-04 6,471E-03 ! sex determination GO:0007530 29 19 2,000 3,489E-04 6,419E-03 ! renal system process GO:0003014 35 19 2,000 3,489E-04 6,368E-03 ! response to UV GO:0009411 75 46 3,000 3,632E-04 6,578E-03 ! regulation of cell adhesion GO:0030155 159 83 4,000 3,708E-04 6,664E-03 ! regulation of defense response GO:0031347 117 84 4,000 3,92E-04 6,989E-03 ! microtubule cytoskeleton organization GO:0000226 120 84 4,000 3,92E-04 6,936E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 3,948E-04 6,931E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 4,082E-04 7,113E-03 ! central nervous system neuron differentiation GO:0021953 33 20 2,000 4,082E-04 7,059E-03 ! positive regulation of locomotion GO:0040017 35 20 2,000 4,082E-04 7,007E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen catabolic process GO:0030574 25 20 2,000 4,082E-04 6,955E-03 ! positive regulation of MAP kinase activity GO:0043406 121 85 4,000 4,141E-04 7,003E-03 ! regulation of membrane potential GO:0042391 128 85 4,000 4,141E-04 6,952E-03 ! heart morphogenesis GO:0003007 65 48 3,000 4,282E-04 7,137E-03 ! regulation of lymphocyte differentiation GO:0045619 69 48 3,000 4,282E-04 7,086E-03 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 2,000 4,737E-04 7,782E-03 ! positive regulation of bone remodeling GO:0046852 33 21 2,000 4,737E-04 7,727E-03 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 36 21 2,000 4,737E-04 7,672E-03 ! dendrite development GO:0016358 35 21 2,000 4,737E-04 7,619E-03 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 4,737E-04 7,566E-03 ! cell aging GO:0007569 32 21 2,000 4,737E-04 7,514E-03 ! platelet activation GO:0030168 28 21 2,000 4,737E-04 7,462E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 4,737E-04 7,411E-03 ! response to glucocorticoid stimulus GO:0051384 33 21 2,000 4,737E-04 7,361E-03 ! positive regulation of growth GO:0045927 67 50 3,000 5,011E-04 7,735E-03 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 5,325E-04 8,165E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 5,325E-04 8,111E-03 ! protein maturation by protein folding GO:0022417 12 5 1,000 5,325E-04 8,058E-03 ! embryonic hemopoiesis GO:0035162 10 5 1,000 5,325E-04 8,005E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 5,325E-04 7,953E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 1,000 5,325E-04 7,902E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! epithelial cell proliferation GO:0050673 6 5 1,000 5,325E-04 7,851E-03 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 5,325E-04 7,801E-03 ! microvillus organization GO:0032528 7 5 1,000 5,325E-04 7,752E-03 GO:0030033|microvillus assembly, ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 1,000 5,325E-04 7,703E-03 ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 1,000 5,325E-04 7,655E-03 ! forebrain neuron development GO:0021884 7 5 1,000 5,325E-04 7,607E-03 ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 5,325E-04 7,56E-03 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 5,325E-04 7,514E-03 ! muscle cell proliferation GO:0033002 8 5 1,000 5,325E-04 7,468E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 5,325E-04 7,423E-03 ! regulation of hair follicle development GO:0051797 9 5 1,000 5,325E-04 7,378E-03 GO:0042634|regulation of hair cycle, ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 5,325E-04 7,334E-03 ! glial cell migration GO:0008347 10 5 1,000 5,325E-04 7,29E-03 ! regulation of mitochondrial depolarization GO:0051900 9 5 1,000 5,325E-04 7,247E-03 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 5,325E-04 7,204E-03 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 1,000 5,325E-04 7,162E-03 ! activation of phospholipase C activity GO:0007202 87 51 3,000 5,407E-04 7,23E-03 GO:0010863|positive regulation of phospholipase C activity, ! protein import into nucleus, translocation GO:0000060 36 22 2,000 5,455E-04 7,253E-03 ! molting cycle process GO:0022404 40 22 2,000 5,455E-04 7,211E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 2,000 5,455E-04 7,17E-03 ! vasculogenesis GO:0001570 33 22 2,000 5,455E-04 7,129E-03 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 5,455E-04 7,089E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of behavior GO:0050795 38 22 2,000 5,455E-04 7,049E-03 ! positive regulation of phospholipase activity GO:0010518 88 52 3,000 5,824E-04 7,484E-03 ! positive regulation of cell adhesion GO:0045785 37 23 2,000 6,24E-04 7,973E-03 ! myelination GO:0042552 35 23 2,000 6,24E-04 7,929E-03 ! response to corticosteroid stimulus GO:0031960 36 23 2,000 6,24E-04 7,886E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 6,24E-04 7,843E-03 ! skeletal system morphogenesis GO:0048705 78 53 3,000 6,264E-04 7,83E-03 ! glucose catabolic process GO:0006007 66 54 3,000 6,727E-04 8,363E-03 ! regulation of phospholipase activity GO:0010517 90 54 3,000 6,727E-04 8,318E-03 ! DNA catabolic process GO:0006308 67 54 3,000 6,727E-04 8,273E-03 ! positive regulation of lipase activity GO:0060193 90 54 3,000 6,727E-04 8,229E-03 ! regulation of oxidoreductase activity GO:0051341 39 24 2,000 7,093E-04 8,632E-03 ! regulation of osteoblast differentiation GO:0045667 37 24 2,000 7,093E-04 8,586E-03 ! regulation of response to external stimulus GO:0032101 139 96 4,000 7,234E-04 8,711E-03 ! negative regulation of response to stimulus GO:0048585 80 56 3,000 7,724E-04 9,253E-03 ! forebrain neuron differentiation GO:0021879 9 6 1,000 7,949E-04 9,473E-03 GO:0021872|generation of neurons in the forebrain, ! regulation of protein export from nucleus GO:0046825 6 6 1,000 7,949E-04 9,424E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 7,949E-04 9,376E-03 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 1,000 7,949E-04 9,328E-03 GO:0031958|corticosteroid receptor signaling pathway, ! pigment granule organization GO:0048753 11 6 1,000 7,949E-04 9,28E-03 ! ER overload response GO:0006983 7 6 1,000 7,949E-04 9,234E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 7,949E-04 9,187E-03 ! male sex determination GO:0030238 9 6 1,000 7,949E-04 9,141E-03 ! spindle checkpoint GO:0031577 14 6 1,000 7,949E-04 9,096E-03 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 1,000 7,949E-04 9,051E-03 ! dendrite morphogenesis GO:0048813 9 6 1,000 7,949E-04 9,006E-03 ! regulation of myeloid cell apoptosis GO:0033032 10 6 1,000 7,949E-04 8,962E-03 ! regulation of meiosis GO:0040020 10 6 1,000 7,949E-04 8,918E-03 GO:0051445|regulation of meiotic cell cycle, ! myeloid dendritic cell activation GO:0001773 10 6 1,000 7,949E-04 8,875E-03 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 1,000 7,949E-04 8,832E-03 ! midbrain development GO:0030901 6 6 1,000 7,949E-04 8,79E-03 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 1,000 7,949E-04 8,748E-03 ! negative regulation of B cell activation GO:0050869 9 6 1,000 7,949E-04 8,706E-03 ! male gonad development GO:0008584 33 25 2,000 8,017E-04 8,739E-03 ! regulation of chromosome organization GO:0033044 35 25 2,000 8,017E-04 8,698E-03 ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 8,017E-04 8,657E-03 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 8,017E-04 8,616E-03 ! extracellular structure organization GO:0043062 156 99 4,000 8,317E-04 8,898E-03 ! protein localization in organelle GO:0033365 161 100 4,000 8,704E-04 9,268E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 9,014E-04 9,554E-03 ! post-embryonic development GO:0009791 42 26 2,000 9,014E-04 9,51E-03 ! negative regulation of protein modification process GO:0031400 50 26 2,000 9,014E-04 9,467E-03 ! multicellular organismal catabolic process GO:0044243 32 26 2,000 9,014E-04 9,424E-03 ! embryonic limb morphogenesis GO:0030326 86 60 3,000 1,002E-03 0,01043288 GO:0035113|embryonic appendage morphogenesis, ! regulation of heart contraction GO:0008016 91 60 3,000 1,002E-03 0,01038589 ! regulation of homeostatic process GO:0032844 105 60 3,000 1,002E-03 0,01033931 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 1,009E-03 0,01035652 ! extracellular matrix organization GO:0030198 103 61 3,000 1,067E-03 0,01090449 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,107E-03 0,01127067 ! microtubule bundle formation GO:0001578 8 7 1,000 1,107E-03 0,01122102 ! central nervous system neuron axonogenesis GO:0021955 14 7 1,000 1,107E-03 0,0111718 GO:0021952|central nervous system projection neuron axonogenesis, ! organ growth GO:0035265 11 7 1,000 1,107E-03 0,01112302 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 1,107E-03 0,01107465 ! behavioral fear response GO:0001662 13 7 1,000 1,107E-03 0,01102671 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 10 7 1,000 1,107E-03 0,01097918 ! response to UV-B GO:0010224 11 7 1,000 1,107E-03 0,01093206 ! B cell lineage commitment GO:0002326 17 7 1,000 1,107E-03 0,01088534 ! T cell lineage commitment GO:0002360 12 7 1,000 1,107E-03 0,01083902 ! peptidyl-threonine modification GO:0018210 18 7 1,000 1,107E-03 0,0107931 ! positive regulation of epidermis development GO:0045684 11 7 1,000 1,107E-03 0,01074756 ! dopamine biosynthetic process GO:0042416 15 7 1,000 1,107E-03 0,0107024 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 1,107E-03 0,01065762 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 1,000 1,107E-03 0,01061321 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 1,000 1,107E-03 0,01056917 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,124E-03 0,01067895 ! ensheathment of neurons GO:0007272 43 28 2,000 1,124E-03 0,010635 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 2,000 1,124E-03 0,01059142 ! regulation of B cell activation GO:0050864 42 28 2,000 1,124E-03 0,01054819 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 1,204E-03 0,01125587 ! regulation of lipase activity GO:0060191 109 63 3,000 1,204E-03 0,0112103 ! cell cycle checkpoint GO:0000075 108 64 3,000 1,277E-03 0,01184211 ! hexose catabolic process GO:0019320 82 64 3,000 1,277E-03 0,01179456 ! collagen metabolic process GO:0032963 40 30 2,000 1,378E-03 0,01267407 ! embryonic skeletal system morphogenesis GO:0048704 42 30 2,000 1,378E-03 0,01262358 ! hindbrain development GO:0030902 45 30 2,000 1,378E-03 0,01257349 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,378E-03 0,01252379 ! cell-substrate adhesion GO:0031589 121 66 3,000 1,432E-03 0,01296762 ! axon extension GO:0048675 11 8 1,000 1,469E-03 0,01325421 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 1,469E-03 0,01320244 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,469E-03 0,01315107 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,469E-03 0,01310009 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,469E-03 0,01304951 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 1,469E-03 0,01299932 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,469E-03 0,01294952 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 1,000 1,469E-03 0,01290009 ! melanin metabolic process GO:0006582 12 8 1,000 1,469E-03 0,01285104 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 1,000 1,469E-03 0,01280236 ! regulation of gliogenesis GO:0014013 20 8 1,000 1,469E-03 0,01275405 GO:0045685|regulation of glial cell differentiation, ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 1,469E-03 0,01270611 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,469E-03 0,01265852 ! regulation of embryonic development GO:0045995 16 8 1,000 1,469E-03 0,01261128 ! response to mechanical stimulus GO:0009612 43 31 2,000 1,517E-03 0,01297101 ! calcium-mediated signaling GO:0019722 50 32 2,000 1,665E-03 0,01418343 ! response to drug GO:0042493 108 69 3,000 1,689E-03 0,01433322 ! eye development GO:0001654 111 70 3,000 1,781E-03 0,0150605 ! positive regulation of phosphorylation GO:0042327 102 70 3,000 1,781E-03 0,01500534 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 1,822E-03 0,01529167 ! carbohydrate homeostasis GO:0033500 39 33 2,000 1,822E-03 0,01523607 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 2,000 1,822E-03 0,01518087 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 2,000 1,822E-03 0,01512606 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 3,000 1,877E-03 0,01552705 ! monosaccharide catabolic process GO:0046365 91 71 3,000 1,877E-03 0,01547139 ! regulation of developmental growth GO:0048638 13 9 1,000 1,88E-03 0,01544468 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 1,88E-03 0,01538972 ! regulation of glycolysis GO:0006110 15 9 1,000 1,88E-03 0,01533515 ! T cell selection GO:0045058 18 9 1,000 1,88E-03 0,01528096 ! epithelial cell development GO:0002064 10 9 1,000 1,88E-03 0,01522715 ! motor axon guidance GO:0008045 14 9 1,000 1,88E-03 0,01517373 ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 1,88E-03 0,01512067 ! positive regulation of phagocytosis GO:0050766 11 9 1,000 1,88E-03 0,01506798 ! oocyte differentiation GO:0009994 12 9 1,000 1,88E-03 0,01501567 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 1,000 1,88E-03 0,01496371 ! spleen development GO:0048536 15 9 1,000 1,88E-03 0,01491211 ! sequestering of metal ion GO:0051238 11 9 1,000 1,88E-03 0,01486086 ! response to nicotine GO:0035094 16 9 1,000 1,88E-03 0,01480997 ! localization within membrane GO:0051668 15 9 1,000 1,88E-03 0,01475943 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 3,000 1,976E-03 0,01545796 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 3,000 1,976E-03 0,01540556 ! negative regulation of organelle organization GO:0010639 115 72 3,000 1,976E-03 0,01535351 ! development of primary male sexual characteristics GO:0046546 44 34 2,000 1,987E-03 0,01538987 ! neuron migration GO:0001764 46 34 2,000 1,987E-03 0,01533823 ! mitotic cell cycle checkpoint GO:0007093 63 34 2,000 1,987E-03 0,01528693 ! mitochondrion organization GO:0007005 104 73 3,000 2,079E-03 0,01593656 ! regulation of action potential in neuron GO:0019228 54 35 2,000 2,162E-03 0,01652009 ! response to oxygen levels GO:0070482 137 74 3,000 2,185E-03 0,01664125 ! protein import into nucleus GO:0006606 118 74 3,000 2,185E-03 0,01658633 ! blood coagulation GO:0007596 116 75 3,000 2,295E-03 0,01736465 GO:0050817|coagulation, ! regulation of ligase activity GO:0051340 114 75 3,000 2,295E-03 0,01730772 ! nuclear import GO:0051170 121 75 3,000 2,295E-03 0,01725116 ! cortical actin cytoskeleton organization GO:0030866 19 10 1,000 2,339E-03 0,017523 ! regulation of phosphatase activity GO:0010921 21 10 1,000 2,339E-03 0,01746611 ! positive regulation of heart contraction GO:0045823 14 10 1,000 2,339E-03 0,01740958 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 2,339E-03 0,01735342 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 2,339E-03 0,01729762 ! B cell proliferation GO:0042100 14 10 1,000 2,339E-03 0,01724218 ! fear response GO:0042596 16 10 1,000 2,339E-03 0,0171871 ! negative regulation of ossification GO:0030279 19 10 1,000 2,339E-03 0,01713236 ! alpha-beta T cell activation GO:0046631 16 10 1,000 2,339E-03 0,01707797 ! DNA methylation GO:0006306 15 10 1,000 2,339E-03 0,01702393 GO:0006305|DNA alkylation, ! salivary gland development GO:0007431 22 10 1,000 2,339E-03 0,01697022 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 2,339E-03 0,01691686 GO:0043470|regulation of carbohydrate catabolic process, ! cardiac cell differentiation GO:0035051 16 10 1,000 2,339E-03 0,01686383 ! response to reactive oxygen species GO:0000302 55 36 2,000 2,346E-03 0,01686117 ! sex differentiation GO:0007548 105 77 3,000 2,527E-03 0,01810393 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 2,000 2,742E-03 0,01958677 ! regulation of T cell proliferation GO:0042129 58 38 2,000 2,742E-03 0,01952613 ! T cell activation GO:0042110 134 79 3,000 2,774E-03 0,01969033 ! cortical cytoskeleton organization GO:0030865 20 11 1,000 2,845E-03 0,02013328 ! virus-host interaction GO:0019048 17 11 1,000 2,845E-03 0,02007152 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,845E-03 0,02001014 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 2,845E-03 0,01994914 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 1,000 2,845E-03 0,0198885 ! adult heart development GO:0007512 11 11 1,000 2,845E-03 0,01982823 ! regulation of phagocytosis GO:0050764 14 11 1,000 2,845E-03 0,01976833 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 1,000 2,845E-03 0,01970878 ! T cell homeostasis GO:0043029 20 11 1,000 2,845E-03 0,0196496 ! digestive tract morphogenesis GO:0048546 15 11 1,000 2,845E-03 0,01959077 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! alcohol catabolic process GO:0046164 104 80 3,000 2,903E-03 0,01993316 ! protein localization in nucleus GO:0034504 133 80 3,000 2,903E-03 0,01987384 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 2,000 2,955E-03 0,02016617 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 2,000 2,955E-03 0,0201065 ! male sex differentiation GO:0046661 53 39 2,000 2,955E-03 0,02004719 ! cell growth GO:0016049 61 39 2,000 2,955E-03 0,01998823 ! hemostasis GO:0007599 125 81 3,000 3,037E-03 0,02048368 ! detection of stimulus involved in sensory perception GO:0050906 50 40 2,000 3,177E-03 0,02136774 ! T cell differentiation GO:0030217 65 40 2,000 3,177E-03 0,02130545 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 3,397E-03 0,02271553 ! palate development GO:0060021 15 12 1,000 3,397E-03 0,02264969 ! positive regulation of cell growth GO:0030307 16 12 1,000 3,397E-03 0,02258423 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 3,397E-03 0,02251914 ! Golgi organization GO:0007030 18 12 1,000 3,397E-03 0,02245443 ! cell-cell junction assembly GO:0007043 18 12 1,000 3,397E-03 0,02239009 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 3,397E-03 0,02232612 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 3,397E-03 0,02226251 ! peptidyl-lysine modification GO:0018205 18 12 1,000 3,397E-03 0,02219927 ! response to gamma radiation GO:0010332 20 12 1,000 3,397E-03 0,02213638 ! regulation of epidermis development GO:0045682 17 12 1,000 3,397E-03 0,02207385 ! epithelial cell differentiation GO:0030855 55 41 2,000 3,41E-03 0,02209178 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 3,613E-03 0,02334532 ! cellular component disassembly GO:0022411 64 42 2,000 3,653E-03 0,02353155 ! embryonic skeletal system development GO:0048706 56 42 2,000 3,653E-03 0,02346582 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 3,905E-03 0,02502122 ! activation of caspase activity GO:0006919 65 43 2,000 3,905E-03 0,02495171 ! skeletal muscle tissue development GO:0007519 123 87 3,000 3,928E-03 0,02502468 GO:0060538|skeletal muscle organ development, ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 3,996E-03 0,0253879 ! exocrine system development GO:0035272 27 13 1,000 3,996E-03 0,02531796 ! negative regulation of mitotic cell cycle GO:0045930 23 13 1,000 3,996E-03 0,0252484 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 3,996E-03 0,02517923 ! cellular pigmentation GO:0033059 24 13 1,000 3,996E-03 0,02511044 ! positive regulation of bone mineralization GO:0030501 19 13 1,000 3,996E-03 0,02504201 ! lymphocyte homeostasis GO:0002260 24 13 1,000 3,996E-03 0,02497397 ! negative regulation of cell migration GO:0030336 92 44 2,000 4,169E-03 0,02598495 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 4,169E-03 0,02591472 ! detection of abiotic stimulus GO:0009582 58 44 2,000 4,169E-03 0,02584486 ! regulation of neurogenesis GO:0050767 153 89 3,000 4,26E-03 0,02633964 ! regulation of T cell activation GO:0050863 128 89 3,000 4,26E-03 0,02626902 ! leukocyte differentiation GO:0002521 143 90 3,000 4,433E-03 0,02726323 ! cell maturation GO:0048469 60 45 2,000 4,443E-03 0,02724943 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 4,639E-03 0,02837911 ! neuron maturation GO:0042551 21 14 1,000 4,639E-03 0,02830384 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 4,639E-03 0,02822896 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 4,639E-03 0,02815448 ! pituitary gland development GO:0021983 23 14 1,000 4,639E-03 0,02808039 ! cellular response to starvation GO:0009267 21 14 1,000 4,639E-03 0,02800668 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 4,639E-03 0,02793337 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of biomineral formation GO:0070169 20 14 1,000 4,639E-03 0,02786044 ! T cell differentiation in the thymus GO:0033077 27 14 1,000 4,639E-03 0,02778788 ! catecholamine biosynthetic process GO:0042423 23 14 1,000 4,639E-03 0,02771571 ! cell fate commitment GO:0045165 141 92 3,000 4,794E-03 0,0285624 ! carbohydrate catabolic process GO:0016052 121 93 3,000 4,981E-03 0,02960177 ! regulation of neuron apoptosis GO:0043523 77 47 2,000 5,023E-03 0,02977477 ! positive regulation of cell size GO:0045793 20 15 1,000 5,327E-03 0,03149856 ! metencephalon development GO:0022037 19 15 1,000 5,327E-03 0,0314178 ! lipid phosphorylation GO:0046834 23 15 1,000 5,327E-03 0,03133745 ! myoblast differentiation GO:0045445 27 15 1,000 5,327E-03 0,0312575 ! regulation of survival gene product expression GO:0045884 20 15 1,000 5,327E-03 0,03117797 ! embryonic digit morphogenesis GO:0042733 18 15 1,000 5,327E-03 0,03109884 ! regulation of vasodilation GO:0042312 24 15 1,000 5,327E-03 0,0310201 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 5,327E-03 0,03094177 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 5,327E-03 0,03086383 ! dopamine metabolic process GO:0042417 30 15 1,000 5,327E-03 0,03078628 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 5,327E-03 0,03070913 ! defense response to virus GO:0051607 27 15 1,000 5,327E-03 0,03063235 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 5,327E-03 0,03055596 ! positive regulation of caspase activity GO:0043280 72 48 2,000 5,329E-03 0,03049036 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 2,000 5,329E-03 0,0304147 ! regulation of DNA replication GO:0006275 75 48 2,000 5,329E-03 0,03033942 ! regulation of binding GO:0051098 151 95 3,000 5,37E-03 0,03049653 ! angiogenesis GO:0001525 149 95 3,000 5,37E-03 0,03042141 ! response to light stimulus GO:0009416 153 96 3,000 5,572E-03 0,03148835 ! germ cell development GO:0007281 68 49 2,000 5,647E-03 0,03183077 ! ear development GO:0043583 72 50 2,000 5,975E-03 0,03359986 ! skeletal muscle fiber development GO:0048741 73 50 2,000 5,975E-03 0,03351791 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 6,059E-03 0,03390763 ! protein amino acid acetylation GO:0006473 28 16 1,000 6,059E-03 0,03382533 ! patterning of blood vessels GO:0001569 24 16 1,000 6,059E-03 0,03374343 ! regulation of protein binding GO:0043393 27 16 1,000 6,059E-03 0,03366192 ! regulation of dephosphorylation GO:0035303 33 16 1,000 6,059E-03 0,03358081 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 1,000 6,059E-03 0,03350009 ! protein export from nucleus GO:0006611 24 16 1,000 6,059E-03 0,03341975 ! negative regulation of immune response GO:0050777 28 16 1,000 6,059E-03 0,0333398 ! diencephalon development GO:0021536 25 16 1,000 6,059E-03 0,03326023 ! oogenesis GO:0048477 23 16 1,000 6,059E-03 0,03318104 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 6,059E-03 0,03310223 ! protein import GO:0017038 156 99 3,000 6,208E-03 0,03383764 ! muscle fiber development GO:0048747 74 51 2,000 6,315E-03 0,03433455 ! negative regulation of cell motion GO:0051271 104 51 2,000 6,315E-03 0,03425357 ! regulation of body fluid levels GO:0050878 154 100 3,000 6,431E-03 0,03480247 ! regulation of translation GO:0006417 151 100 3,000 6,431E-03 0,03472077 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 1,000 6,834E-03 0,03681097 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 6,834E-03 0,03672496 ! keratinization GO:0031424 17 17 1,000 6,834E-03 0,03663936 ! regulation of viral genome replication GO:0045069 24 17 1,000 6,834E-03 0,03655415 ! actin filament bundle formation GO:0051017 26 17 1,000 6,834E-03 0,03646934 ! neuromuscular junction development GO:0007528 23 17 1,000 6,834E-03 0,03638492 ! cell-cell junction organization GO:0045216 25 17 1,000 6,834E-03 0,03630089 ! proximal/distal pattern formation GO:0009954 25 17 1,000 6,834E-03 0,03621725 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 6,834E-03 0,03613399 ! detection of external stimulus GO:0009581 66 54 2,000 7,402E-03 0,03904569 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 7,651E-03 0,04027037 ! protein amino acid ADP-ribosylation GO:0006471 27 18 1,000 7,651E-03 0,04017843 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 1,000 7,651E-03 0,04008691 GO:0050886|endocrine process, ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 7,651E-03 0,0399958 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 1,000 7,651E-03 0,03990511 ! somitogenesis GO:0001756 24 18 1,000 7,651E-03 0,03981483 ! cellular response to nutrient levels GO:0031669 27 18 1,000 7,651E-03 0,03972495 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 7,651E-03 0,03963548 ! gut development GO:0048565 26 18 1,000 7,651E-03 0,03954641 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 8,51E-03 0,04388818 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 8,51E-03 0,04378999 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 8,51E-03 0,04369225 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regeneration GO:0031099 32 19 1,000 8,51E-03 0,04359494 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 8,51E-03 0,04349806 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 8,51E-03 0,04340161 ! response to starvation GO:0042594 30 19 1,000 8,51E-03 0,04330559 ! plasma membrane fusion GO:0045026 23 19 1,000 8,51E-03 0,04320999 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 1,000 8,51E-03 0,04311482 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 8,51E-03 0,04302006 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 8,51E-03 0,04292572 ! protein stabilization GO:0050821 26 19 1,000 8,51E-03 0,04283179 ! developmental maturation GO:0021700 75 57 2,000 8,593E-03 0,04315241 ! gonad development GO:0008406 79 57 2,000 8,593E-03 0,04305839 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 9,014E-03 0,04506774 ! hindlimb morphogenesis GO:0035137 32 20 1,000 9,411E-03 0,04695165 ! response to ethanol GO:0045471 37 20 1,000 9,411E-03 0,04685002 ! multicellular organismal response to stress GO:0033555 32 20 1,000 9,411E-03 0,04674883 ! DNA modification GO:0006304 28 20 1,000 9,411E-03 0,04664808 ! positive regulation of osteoblast differentiation GO:0045669 33 20 1,000 9,411E-03 0,04654776 ! positive regulation of B cell activation GO:0050871 31 20 1,000 9,411E-03 0,04644787 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 2,000 9,446E-03 0,04652209 ! lung development GO:0030324 94 59 2,000 9,446E-03 0,04642269 ! actin filament organization GO:0007015 95 59 2,000 9,446E-03 0,0463237 ! meiosis GO:0007126 96 61 2,000 0,0103468 0,05063328 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 2,000 0,0103468 0,05052578 ! negative regulation of ligase activity GO:0051352 91 61 2,000 0,0103468 0,05041873 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 0,0103468 0,05031214 ! myeloid leukocyte differentiation GO:0002573 33 21 1,000 0,01035149 0,05022873 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 0,01035149 0,05012298 ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 1,000 0,01035149 0,05001768 ! protein amino acid acylation GO:0043543 37 21 1,000 0,01035149 0,04991282 ! ovarian follicle development GO:0001541 30 21 1,000 0,01035149 0,0498084 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 0,01035149 0,04970442 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 0,01035149 0,04960087 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 0,01035149 0,04949775 ! regulation of vasoconstriction GO:0019229 31 21 1,000 0,01035149 0,04939506 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 0,01035149 0,04929279 ! regulation of bone mineralization GO:0030500 29 21 1,000 0,01035149 0,04919094 ! response to cytokine stimulus GO:0034097 47 21 1,000 0,01035149 0,04908952 ! acetyl-CoA catabolic process GO:0046356 31 21 1,000 0,01035149 0,04898851 GO:0006099|tricarboxylic acid cycle, ! respiratory tube development GO:0030323 99 62 2,000 0,01081526 0,05107821 ! meiotic cell cycle GO:0051321 97 62 2,000 0,01081526 0,05097354 ! regulation of transcription factor activity GO:0051090 97 63 2,000 0,01129582 0,05312964 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 0,01129582 0,05302121 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01133208 0,05308307 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 0,01133208 0,05297517 ! coenzyme catabolic process GO:0009109 33 22 1,000 0,01133208 0,05286772 ! leukocyte homeostasis GO:0001776 33 22 1,000 0,01133208 0,0527607 ! protein tetramerization GO:0051262 39 22 1,000 0,01133208 0,05265411 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 2,000 0,01178856 0,05466468 ! respiratory system development GO:0060541 100 64 2,000 0,01178856 0,05455469 ! regulation of caspase activity GO:0043281 97 65 2,000 0,01229351 0,05677724 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 0,01229351 0,05666346 ! protein oligomerization GO:0051259 100 65 2,000 0,01229351 0,05655013 ! acetyl-CoA metabolic process GO:0006084 33 23 1,000 0,0123519 0,05670532 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,0123519 0,05659237 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 0,0123519 0,05647986 ! regulation of viral reproduction GO:0050792 32 23 1,000 0,0123519 0,05636779 ! interaction with host GO:0051701 37 23 1,000 0,0123519 0,05625617 ! lymphocyte proliferation GO:0046651 36 23 1,000 0,0123519 0,05614499 ! regulation of biomineral formation GO:0070167 31 23 1,000 0,0123519 0,05603425 ! cellular response to oxidative stress GO:0034599 33 23 1,000 0,0123519 0,05592395 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 1,000 0,0123519 0,05581408 ! liver development GO:0001889 40 23 1,000 0,0123519 0,05570464 ! regulation of Rho protein signal transduction GO:0035023 111 66 2,000 0,01281072 0,05766077 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01334023 0,05992683 ! regulation of neuron differentiation GO:0045664 107 67 2,000 0,01334023 0,05981001 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 0,01341032 0,06000725 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01341032 0,05989073 ! response to toxin GO:0009636 38 24 1,000 0,01341032 0,05977467 ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 0,01341032 0,05965905 ! development of primary sexual characteristics GO:0045137 92 68 2,000 0,01388209 0,06163863 ! activation of protein kinase activity GO:0032147 102 69 2,000 0,01443633 0,06397604 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01450672 0,06416433 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 0,01450672 0,06404117 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01450672 0,06391849 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 1,000 0,01450672 0,06379628 GO:0032943|mononuclear cell proliferation, ! response to metal ion GO:0010038 103 70 2,000 0,01500299 0,0658528 ! lymphocyte differentiation GO:0030098 113 71 2,000 0,01558208 0,06826437 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,01564049 0,06839 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,01617366 0,07058711 ! negative regulation of transport GO:0051051 116 73 2,000 0,01677773 0,07308479 ! response to steroid hormone stimulus GO:0048545 114 73 2,000 0,01677773 0,07294664 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 1,000 0,01681104 0,07295358 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 43 27 1,000 0,01681104 0,0728162 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 1,000 0,01681104 0,07267932 ! response to ionizing radiation GO:0010212 47 27 1,000 0,01681104 0,07254296 ! cofactor catabolic process GO:0051187 45 27 1,000 0,01681104 0,07240712 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,01681104 0,07227178 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,01681104 0,07213694 ! positive regulation of lymphocyte activation GO:0051251 108 74 2,000 0,01739432 0,0745008 ! phenol metabolic process GO:0018958 44 28 1,000 0,01801777 0,07702764 ! positive regulation of endocytosis GO:0045807 33 28 1,000 0,01801777 0,07688473 ! cholesterol homeostasis GO:0042632 46 28 1,000 0,01801777 0,07674235 GO:0055092|sterol homeostasis, ! response to organic cyclic substance GO:0014070 47 28 1,000 0,01801777 0,0766005 ! regulation of systemic arterial blood pressure GO:0003073 47 28 1,000 0,01801777 0,07645917 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,01801777 0,07631836 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 0,01801777 0,07617807 ! myeloid leukocyte activation GO:0002274 39 28 1,000 0,01801777 0,07603829 ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,01801777 0,07589903 ! placenta development GO:0001890 37 28 1,000 0,01801777 0,07576027 ! response to inorganic substance GO:0010035 115 75 2,000 0,01802345 0,07564586 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,01926008 0,08068887 ! ovulation cycle process GO:0022602 41 29 1,000 0,01926008 0,08054216 ! tissue homeostasis GO:0001894 42 29 1,000 0,01926008 0,08039599 GO:0048871|multicellular organismal homeostasis, ! regulation of DNA binding GO:0051101 119 77 2,000 0,0193194 0,0804975 ! positive regulation of protein modification process GO:0031401 107 78 2,000 0,01998625 0,08312544 ! positive regulation of neurogenesis GO:0050769 45 30 1,000 0,0205374 0,08526358 ! ovulation cycle GO:0042698 43 30 1,000 0,0205374 0,08510995 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,0205374 0,08495688 ! response to heat GO:0009408 41 30 1,000 0,0205374 0,08480435 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 0,02135773 0,08803364 GO:0010498|proteasomal protein catabolic process, ! mammary gland development GO:0030879 57 31 1,000 0,02184915 0,08989811 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 0,02184915 0,08973758 ! odontogenesis GO:0042476 50 31 1,000 0,02184915 0,08957762 ! segmentation GO:0035282 41 31 1,000 0,02184915 0,08941823 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,02184915 0,0892594 ! biogenic amine biosynthetic process GO:0042401 44 31 1,000 0,02184915 0,08910114 ! positive regulation of cell activation GO:0050867 120 81 2,000 0,02206237 0,08981143 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 2,000 0,02277963 0,09256739 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 2,000 0,02277963 0,09240413 ! regulation of muscle development GO:0048634 48 32 1,000 0,02319476 0,09392244 ! meiosis I GO:0007127 52 32 1,000 0,02319476 0,09375737 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02319476 0,09359289 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,02319476 0,09342898 ! cytokine production GO:0001816 44 32 1,000 0,02319476 0,09326564 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,02319476 0,09310287 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02457367 0,09846591 ! ear morphogenesis GO:0042471 42 33 1,000 0,02457367 0,09829466 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 1,000 0,02457367 0,09812401 ! female gonad development GO:0008585 49 33 1,000 0,02457367 0,09795395 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,02457367 0,09778448 ! lipid homeostasis GO:0055088 55 33 1,000 0,02457367 0,0976156 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,02457367 0,0974473 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,02457367 0,09727957 ! cytokinesis GO:0000910 52 33 1,000 0,02457367 0,09711243 ! transcription initiation GO:0006352 118 85 2,000 0,02500702 0,09865549 ! regulation of protein localization GO:0032880 132 85 2,000 0,02500702 0,09848656 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,02598531 0,10216448 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 0,02598531 0,10199014 ! female gamete generation GO:0007292 43 34 1,000 0,02598531 0,10181639 ! aerobic respiration GO:0009060 47 34 1,000 0,02598531 0,10164323 ! embryonic organ development GO:0048568 45 34 1,000 0,02598531 0,10147067 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 0,02598531 0,10129868 ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 0,02655493 0,10334406 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,02742915 0,10656596 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,02742915 0,10638626 ! glycogen metabolic process GO:0005977 48 35 1,000 0,02742915 0,10620716 ! pigment metabolic process GO:0042440 61 35 1,000 0,02742915 0,10602866 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,02742915 0,10585076 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 0,02742915 0,10567345 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,02890464 0,11117168 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 0,02890464 0,11098609 ! hormone-mediated signaling GO:0009755 49 36 1,000 0,02890464 0,11080111 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,02890464 0,11061675 GO:0046660|female sex differentiation, ! glucan metabolic process GO:0044042 49 36 1,000 0,02890464 0,110433 GO:0006073|cellular glucan metabolic process, ! gliogenesis GO:0042063 71 38 1,000 0,0319484 0,12185958 ! response to oxidative stress GO:0006979 141 94 2,000 0,03236786 0,12325509 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,03351563 0,12741478 ! JNK cascade GO:0007254 54 39 1,000 0,03351563 0,12720452 ! developmental growth GO:0048589 62 39 1,000 0,03351563 0,12699496 ! synapse organization GO:0050808 55 39 1,000 0,03351563 0,12678609 ! protein maturation GO:0051604 129 96 2,000 0,034141 0,12893975 ! response to calcium ion GO:0051592 58 40 1,000 0,03511238 0,13239094 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,03511238 0,13217426 ! regulation of tube size GO:0035150 60 40 1,000 0,03511238 0,13195829 GO:0050880|regulation of blood vessel size, ! B cell differentiation GO:0030183 62 40 1,000 0,03511238 0,13174303 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,03511238 0,13152846 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,03511238 0,13131459 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03635869 0,13575487 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03635869 0,13553484 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03635869 0,13531553 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03635869 0,13509693 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03635869 0,13487903 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03635869 0,13466183 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03635869 0,13444533 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03635869 0,13422953 ! sleep GO:0030431 11 5 0,000 0,03635869 0,13401442 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03635869 0,1338 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03635869 0,13358626 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03635869 0,1333732 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03635869 0,13316082 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03635869 0,13294912 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03635869 0,13273809 ! tongue development GO:0043586 6 5 0,000 0,03635869 0,13252773 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03635869 0,13231803 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03635869 0,132109 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03635869 0,13190063 ! cobalt ion transport GO:0006824 9 5 0,000 0,03635869 0,13169291 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03635869 0,13148584 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03635869 0,13127943 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03635869 0,13107366 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03635869 0,13086854 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03635869 0,13066406 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03635869 0,13046021 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03635869 0,13025701 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03635869 0,13005443 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03635869 0,12985248 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03635869 0,12965116 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03635869 0,12945046 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03635869 0,12925038 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03635869 0,12905092 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03635869 0,12885208 ! malate metabolic process GO:0006108 7 5 0,000 0,03635869 0,12865384 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03635869 0,12845622 ! behavioral response to pain GO:0048266 7 5 0,000 0,03635869 0,1282592 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03635869 0,12806278 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03635869 0,12786697 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03635869 0,12767175 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03635869 0,12747713 ! mating behavior GO:0007617 6 5 0,000 0,03635869 0,1272831 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03635869 0,12708966 ! rhythmic behavior GO:0007622 12 5 0,000 0,03635869 0,12689681 ! copulation GO:0007620 7 5 0,000 0,03635869 0,12670454 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03635869 0,12651286 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03635869 0,12632175 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03635869 0,12613122 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03635869 0,12594126 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03635869 0,12575188 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03635869 0,12556306 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03635869 0,12537481 ! response to protozoan GO:0001562 9 5 0,000 0,03635869 0,12518712 ! lymph vessel development GO:0001945 7 5 0,000 0,03635869 0,125 ! endochondral ossification GO:0001958 12 5 0,000 0,03635869 0,12481343 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03635869 0,12462742 ! parathyroid gland development GO:0060017 8 5 0,000 0,03635869 0,12444196 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03635869 0,12425705 ! anagen GO:0042640 6 5 0,000 0,03635869 0,1240727 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03635869 0,12388888 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03635869 0,12370562 ! nuclear migration GO:0007097 10 5 0,000 0,03635869 0,12352289 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03635869 0,1233407 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03635869 0,12315905 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03635869 0,12297794 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03635869 0,12279735 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03635869 0,1226173 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03635869 0,12243777 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03635869 0,12225877 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03635869 0,12208029 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03635869 0,12190233 ! ovulation GO:0030728 6 5 0,000 0,03635869 0,12172489 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03635869 0,12154796 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,03635869 0,12137155 ! response to pH GO:0009268 9 5 0,000 0,03635869 0,12119565 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03635869 0,12102026 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03635869 0,12084537 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03635869 0,12067099 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03635869 0,12049711 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03635869 0,12032374 ! polyol catabolic process GO:0046174 7 5 0,000 0,03635869 0,12015086 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03635869 0,11997848 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03635869 0,11980659 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03635869 0,11963519 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03635869 0,11946428 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03635869 0,11929386 ! urea metabolic process GO:0019627 6 5 0,000 0,03635869 0,11912393 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03635869 0,11895448 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03635869 0,11878551 ! neutrophil activation GO:0042119 5 5 0,000 0,03635869 0,11861702 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03635869 0,118449 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03635869 0,11828147 ! response to food GO:0032094 5 5 0,000 0,03635869 0,1181144 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03635869 0,11794781 GO:0043088|regulation of Cdc42 GTPase activity, ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03635869 0,11778169 ! melanosome organization GO:0032438 7 5 0,000 0,03635869 0,11761603 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03635869 0,11745084 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03635869 0,11728611 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03635869 0,11712184 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03635869 0,11695804 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03635869 0,11679469 ! nucleoside transport GO:0015858 6 5 0,000 0,03635869 0,1166318 ! nucleoside salvage GO:0043174 7 5 0,000 0,03635869 0,11646936 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03635869 0,11630737 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03635869 0,11614583 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03635869 0,11598474 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03635869 0,1158241 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03635869 0,1156639 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03635869 0,11550414 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03635869 0,11534482 ! depyrimidination GO:0045008 8 5 0,000 0,03635869 0,11518595 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03635869 0,11502751 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03635869 0,1148695 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03635869 0,11471193 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03635869 0,11455479 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03635869 0,11439808 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03635869 0,1142418 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03635869 0,11408594 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03635869 0,11393051 ! monocyte differentiation GO:0030224 8 5 0,000 0,03635869 0,11377551 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03635869 0,11362092 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03635869 0,11346675 ! centrosome duplication GO:0051298 5 5 0,000 0,03635869 0,113313 ! response to UV-C GO:0010225 6 5 0,000 0,03635869 0,11315967 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03635869 0,11300675 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03635869 0,11285425 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03635869 0,11270215 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03635869 0,11255047 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03635869 0,11239919 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03635869 0,11224832 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03635869 0,11209785 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03635869 0,11194779 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03635869 0,11179812 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03635869 0,11164886 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03635869 0,1115 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03635869 0,11135153 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03635869 0,11120345 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03635869 0,11105577 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03635869 0,11090848 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03635869 0,11076159 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03635869 0,11061508 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03635869 0,11046895 ! neural tube patterning GO:0021532 6 5 0,000 0,03635869 0,11032322 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03635869 0,11017786 ! histone demethylation GO:0016577 9 5 0,000 0,03635869 0,11003289 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03635869 0,1098883 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03635869 0,10974409 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03635869 0,10960026 ! enteric nervous system development GO:0048484 8 5 0,000 0,03635869 0,1094568 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03635869 0,10931372 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03635869 0,10917101 ! transcription termination GO:0006353 8 5 0,000 0,03635869 0,10902868 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03635869 0,10888672 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03635869 0,10874512 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03635869 0,10860389 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03635869 0,10846303 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03635869 0,10832254 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03635869 0,1081824 GO:0015991|ATP hydrolysis coupled proton transport, ! protein destabilization GO:0031648 6 5 0,000 0,03635869 0,10804263 ! apical protein localization GO:0045176 6 5 0,000 0,03635869 0,10790322 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03635869 0,10776417 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03635869 0,10762548 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03635869 0,10748714 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03635869 0,10734916 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03635869 0,10721153 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03635869 0,10707426 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03635869 0,10693734 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03635869 0,10680076 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03635869 0,10666454 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03635869 0,10652866 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03635869 0,10639313 ! neural plate development GO:0001840 6 5 0,000 0,03635869 0,10625794 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03635869 0,10612309 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03635869 0,10598859 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03635869 0,10585443 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03635869 0,1057206 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03635869 0,10558712 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03635869 0,10545397 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03635869 0,10532116 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03635869 0,10518868 ! spindle assembly GO:0051225 5 5 0,000 0,03635869 0,10505653 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03635869 0,10492471 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03635869 0,10479323 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03635869 0,10466207 ! organ regeneration GO:0031100 7 5 0,000 0,03635869 0,10453125 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03635869 0,10440075 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03635869 0,10427057 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03635869 0,10414072 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03635869 0,10401119 GO:0055081|anion homeostasis, ! energy reserve metabolic process GO:0006112 59 41 1,000 0,03673815 0,10496615 ! glucose transport GO:0015758 52 41 1,000 0,03673815 0,10483592 ! endosome transport GO:0016197 71 41 1,000 0,03673815 0,10470601 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,03673815 0,10457643 ! biopolymer methylation GO:0043414 62 41 1,000 0,03673815 0,10444716 ! mitochondrial transport GO:0006839 60 42 1,000 0,03839244 0,10901556 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,03839244 0,10888114 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,03839244 0,10874705 ! hexose transport GO:0008645 54 42 1,000 0,03839244 0,10861329 GO:0015749|monosaccharide transport, ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,03839244 0,10847985 ! positive regulation of binding GO:0051099 59 43 1,000 0,04007473 0,11309432 ! vesicle organization GO:0016050 79 43 1,000 0,04007473 0,11295572 ! methylation GO:0032259 64 43 1,000 0,04007473 0,11281747 ! activation of adenylate cyclase activity GO:0007190 76 44 1,000 0,04178453 0,11748706 ! tRNA transcription GO:0009304 11 6 0,000 0,04347146 0,12208101 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04347146 0,12193213 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04347146 0,12178362 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04347146 0,12163546 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04347146 0,12148766 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04347146 0,12134023 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04347146 0,12119315 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04347146 0,12104643 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04347146 0,12090006 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04347146 0,12075404 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04347146 0,12060838 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04347146 0,12046307 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04347146 0,12031811 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04347146 0,1201735 ! male meiosis GO:0007140 7 6 0,000 0,04347146 0,12002923 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04347146 0,11988531 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04347146 0,11974173 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04347146 0,1195985 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04347146 0,11945561 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04347146 0,11931306 ! neuron adhesion GO:0007158 9 6 0,000 0,04347146 0,11917086 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04347146 0,11902899 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04347146 0,11888745 ! signal peptide processing GO:0006465 8 6 0,000 0,04347146 0,11874626 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04347146 0,1186054 ! mRNA stabilization GO:0048255 15 6 0,000 0,04347146 0,11846487 GO:0043489|RNA stabilization, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04347146 0,11832467 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04347146 0,11818481 ! opsonization GO:0008228 8 6 0,000 0,04347146 0,11804528 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04347146 0,11790607 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04347146 0,11776719 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04347146 0,11762864 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04347146 0,11749042 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04347146 0,11735252 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04347146 0,11721495 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04347146 0,11707769 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04347146 0,11694076 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04347146 0,11680414 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04347146 0,11666785 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04347146 0,11653187 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04347146 0,11639621 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04347146 0,11626087 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04347146 0,11612584 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04347146 0,11599112 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04347146 0,11585672 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04347146 0,11572263 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04347146 0,11558884 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04347146 0,11545537 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04347146 0,1153222 ! thymic T cell selection GO:0045061 12 6 0,000 0,04347146 0,11518934 ! protein lipoylation GO:0009249 10 6 0,000 0,04347146 0,11505679 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04347146 0,11492454 ! drug transport GO:0015893 6 6 0,000 0,04347146 0,11479259 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04347146 0,11466095 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04347146 0,11452961 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04347146 0,11439857 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04347146 0,11426783 ! histidine metabolic process GO:0006547 6 6 0,000 0,04347146 0,11413738 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04347146 0,11400724 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04347146 0,11387739 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04347146 0,11374784 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04347146 0,11361858 ! adenohypophysis development GO:0021984 10 6 0,000 0,04347146 0,11348961 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04347146 0,11336094 ! hyperosmotic response GO:0006972 8 6 0,000 0,04347146 0,11323256 ! microtubule nucleation GO:0007020 10 6 0,000 0,04347146 0,11310447 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04347146 0,11297666 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04347146 0,11284915 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04347146 0,11272193 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04347146 0,11259499 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04347146 0,11246833 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,04347146 0,11234196 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04347146 0,11221588 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04347146 0,11209008 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04347146 0,11196456 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04347146 0,11183932 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04347146 0,11171436 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04347146 0,11158967 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04347146 0,11146527 ! neuron apoptosis GO:0051402 8 6 0,000 0,04347146 0,11134114 ! organic alcohol transport GO:0015850 9 6 0,000 0,04347146 0,11121729 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04347146 0,11109372 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04347146 0,11097042 ! carnitine transport GO:0015879 8 6 0,000 0,04347146 0,11084739 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04347146 0,11072464 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04347146 0,11060215 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04347146 0,11047994 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04347146 0,110358 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04347146 0,11023633 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04347146 0,11011492 ! parturition GO:0007567 12 6 0,000 0,04347146 0,10999378 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04347146 0,10987291 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04347146 0,1097523 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04347146 0,10963196 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04347146 0,10951188 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04347146 0,10939207 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04347146 0,10927251 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04347146 0,10915322 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04347146 0,10903419 ! macrophage differentiation GO:0030225 10 6 0,000 0,04347146 0,10891541 ! astrocyte development GO:0014002 14 6 0,000 0,04347146 0,1087969 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04347146 0,10867864 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04347146 0,10856064 ! interaction with symbiont GO:0051702 8 6 0,000 0,04347146 0,10844289 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04347146 0,1083254 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04347146 0,10820817 ! eating behavior GO:0042755 6 6 0,000 0,04347146 0,10809119 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04347146 0,10797446 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04347146 0,10785798 ! response to copper ion GO:0046688 9 6 0,000 0,04347146 0,10774175 ! DNA topological change GO:0006265 8 6 0,000 0,04347146 0,10762578 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04347146 0,10751005 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,04347146 0,10739457 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04347146 0,10727934 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04347146 0,10716436 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04347146 0,10704962 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04347146 0,10693513 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04347146 0,10682088 ! gas homeostasis GO:0033483 11 6 0,000 0,04347146 0,10670688 ! hair follicle maturation GO:0048820 7 6 0,000 0,04347146 0,10659312 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04347146 0,1064796 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04347146 0,10636633 ! Schwann cell development GO:0014044 14 6 0,000 0,04347146 0,10625329 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04347146 0,1061405 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04347146 0,10602794 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04347146 0,10591562 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04347146 0,10580354 ! histone ubiquitination GO:0016574 7 6 0,000 0,04347146 0,1056917 ! G2 phase GO:0051319 13 6 0,000 0,04347146 0,10558009 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04347146 0,10546872 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04347146 0,10535758 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04347146 0,10524668 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04347146 0,10513601 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04347146 0,10502558 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04347146 0,10491537 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04347146 0,1048054 ! receptor internalization GO:0031623 9 6 0,000 0,04347146 0,10469565 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04347146 0,10458614 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04347146 0,10447685 ! protein deubiquitination GO:0016579 8 6 0,000 0,04347146 0,1043678 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04347146 0,10425897 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04347146 0,10415036 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04347146 0,10404199 ! axonal fasciculation GO:0007413 9 6 0,000 0,04347146 0,10393383 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04347146 0,10382591 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04347146 0,1037182 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04347146 0,10361072 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04347146 0,10350347 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04347146 0,10339643 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04347146 0,10328962 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04347146 0,10318302 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04347146 0,10307665 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04347146 0,10297049 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04347146 0,10286456 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04347146 0,10275884 ! adult feeding behavior GO:0008343 6 6 0,000 0,04347146 0,10265333 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04347146 0,10254805 ! blastocyst growth GO:0001832 15 6 0,000 0,04347146 0,10244298 ! pigment granule transport GO:0051904 12 6 0,000 0,04347146 0,10233812 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04347146 0,10223348 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04347146 0,10212906 ! catecholamine transport GO:0051937 7 6 0,000 0,04347146 0,10202484 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04347146 0,10192084 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04347146 0,10181706 ! protein prenylation GO:0018342 10 6 0,000 0,04347146 0,10171348 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04347146 0,10161011 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04347146 0,10150695 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04347146 0,101404 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04347146 0,10130126 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04347146 0,10119873 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,04352135 0,10121244 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 1,000 0,04528471 0,1052069 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,04528471 0,10510074 ! histone modification GO:0016570 68 46 1,000 0,04528471 0,10499479 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,04707412 0,10903372 ! endocrine system development GO:0035270 83 47 1,000 0,04707412 0,10892403 ! covalent chromatin modification GO:0016569 75 47 1,000 0,04707412 0,10881456 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 1,000 0,04707412 0,1087053 ! positive regulation of cyclase activity GO:0031281 87 47 1,000 0,04707412 0,10859627 ! response to temperature stimulus GO:0009266 62 48 1,000 0,04888912 0,11267032 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,04888912 0,11255754 ! positive regulation of lyase activity GO:0051349 88 48 1,000 0,04888912 0,11244498 ! regulation of endocytosis GO:0030100 63 48 1,000 0,04888912 0,11233264 ! nuclear export GO:0051168 69 48 1,000 0,04888912 0,11222054 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,05053212 0,11587625 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05053212 0,11576083 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,05053212 0,11564565 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05053212 0,11553069 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05053212 0,11541597 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05053212 0,11530147 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05053212 0,11518719 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05053212 0,11507315 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05053212 0,11495933 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05053212 0,11484573 ! reproductive behavior GO:0019098 12 7 0,000 0,05053212 0,11473236 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,05053212 0,11461921 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,05053212 0,11450628 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05053212 0,11439358 ! oligopeptide transport GO:0006857 11 7 0,000 0,05053212 0,1142811 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05053212 0,11416884 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05053212 0,1140568 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,05053212 0,11394498 ! RNA methylation GO:0001510 11 7 0,000 0,05053212 0,11383338 ! pericardium development GO:0060039 8 7 0,000 0,05053212 0,11372199 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05053212 0,11361083 ! fibril organization GO:0043206 13 7 0,000 0,05053212 0,11349988 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,05053212 0,11338915 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05053212 0,11327863 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05053212 0,11316833 ! lipoprotein transport GO:0042953 9 7 0,000 0,05053212 0,11305825 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,05053212 0,11294837 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05053212 0,11283872 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05053212 0,11272927 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05053212 0,11262004 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05053212 0,11251101 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05053212 0,1124022 ! chemosensory behavior GO:0007635 9 7 0,000 0,05053212 0,1122936 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,05053212 0,11218521 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,05053212 0,11207703 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,05053212 0,11196905 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05053212 0,11186129 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05053212 0,11175373 ! reflex GO:0060004 12 7 0,000 0,05053212 0,11164638 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05053212 0,11153923 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05053212 0,11143229 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05053212 0,11132555 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05053212 0,11121902 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05053212 0,11111269 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05053212 0,11100657 ! spinal cord patterning GO:0021511 7 7 0,000 0,05053212 0,11090065 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,05053212 0,11079493 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,05053212 0,11068941 ! adrenal gland development GO:0030325 17 7 0,000 0,05053212 0,11058409 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05053212 0,11047897 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,05053212 0,11037405 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05053212 0,11026933 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05053212 0,11016481 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05053212 0,11006049 ! endosome organization GO:0007032 10 7 0,000 0,05053212 0,10995636 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05053212 0,10985244 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05053212 0,1097487 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05053212 0,10964517 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05053212 0,10954183 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05053212 0,10943868 ! galactose metabolic process GO:0006012 10 7 0,000 0,05053212 0,10933573 ! vesicle fusion GO:0006906 15 7 0,000 0,05053212 0,10923297 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05053212 0,1091304 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,05053212 0,10902803 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05053212 0,10892585 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05053212 0,10882386 ! retinol metabolic process GO:0042572 9 7 0,000 0,05053212 0,10872206 ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,05053212 0,10862045 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05053212 0,10851903 ! rRNA modification GO:0000154 12 7 0,000 0,05053212 0,1084178 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05053212 0,10831675 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,05053212 0,1082159 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05053212 0,10811524 ! intermediate filament organization GO:0045109 11 7 0,000 0,05053212 0,10801476 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05053212 0,10791446 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,05053212 0,10781436 ! fibrinolysis GO:0042730 9 7 0,000 0,05053212 0,10771444 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05053212 0,1076147 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,05053212 0,10751515 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,05053212 0,10741578 ! response to tropane GO:0014073 13 7 0,000 0,05053212 0,1073166 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,05053212 0,1072176 ! melanosome localization GO:0032400 10 7 0,000 0,05053212 0,10711878 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05053212 0,10702015 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05053212 0,10692169 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,05053212 0,10682342 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05053212 0,10672532 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05053212 0,10662741 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05053212 0,10652968 ! mast cell activation GO:0045576 9 7 0,000 0,05053212 0,10643212 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05053212 0,10633475 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,05053212 0,10623755 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05053212 0,10614053 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05053212 0,10604368 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,05053212 0,10594702 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,05053212 0,10585053 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,05053212 0,10575421 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,05053212 0,10565807 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05053212 0,10556211 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,05053212 0,10546631 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05053212 0,1053707 ! regulation of lipid transport GO:0032368 13 7 0,000 0,05053212 0,10527525 ! response to tumor cell GO:0002347 12 7 0,000 0,05053212 0,10517998 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05053212 0,10508488 ! neuroblast proliferation GO:0007405 13 7 0,000 0,05053212 0,10498995 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05053212 0,1048952 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,05053212 0,10480061 ! diuresis GO:0030146 12 7 0,000 0,05053212 0,1047062 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05053212 0,10461195 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05053212 0,10451788 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,05053212 0,10442397 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05053212 0,10433023 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05053212 0,10423666 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05053212 0,10414326 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,05053212 0,10405002 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05053212 0,10395696 ! lymph node development GO:0048535 9 7 0,000 0,05053212 0,10386406 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05053212 0,10377132 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05053212 0,10367875 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05053212 0,10358634 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05053212 0,1034941 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05053212 0,10340203 ! ATP catabolic process GO:0006200 10 7 0,000 0,05053212 0,10331011 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05053212 0,10321836 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,05053212 0,10312678 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05053212 0,10303535 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05053212 0,10294409 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05053212 0,10285299 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05053212 0,10276205 ! muscle adaptation GO:0043500 12 7 0,000 0,05053212 0,10267127 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05053212 0,10258065 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05053212 0,10249019 ! retina homeostasis GO:0001895 9 7 0,000 0,05053212 0,10239989 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05053212 0,10230975 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05053212 0,10221977 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,05053212 0,10212995 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05053212 0,10204028 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05053212 0,10195077 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,05072923 0,10225875 ! RNA elongation GO:0006354 62 49 1,000 0,05072923 0,10216921 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,05072923 0,10207982 ! maintenance of location GO:0051235 84 49 1,000 0,05072923 0,10199059 ! membrane fusion GO:0006944 80 50 1,000 0,05259399 0,10564733 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,05259399 0,10555514 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,05259399 0,10546311 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 1,000 0,05259399 0,10537124 ! lipid modification GO:0030258 73 50 1,000 0,05259399 0,10527954 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,05448295 0,1089659 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,05639565 0,1126933 ! establishment of organelle localization GO:0051656 85 52 1,000 0,05639565 0,11259548 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05754107 0,1147827 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05754107 0,11468324 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05754107 0,11458395 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05754107 0,11448482 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05754107 0,11438587 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05754107 0,1142871 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05754107 0,11418849 ! phosphate transport GO:0006817 10 8 0,000 0,05754107 0,11409005 ! N-glycan processing GO:0006491 12 8 0,000 0,05754107 0,11399178 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,05754107 0,11389368 ! UTP metabolic process GO:0046051 8 8 0,000 0,05754107 0,11379575 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05754107 0,11369799 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05754107 0,11360039 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05754107 0,11350296 ! succinate metabolic process GO:0006105 14 8 0,000 0,05754107 0,1134057 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05754107 0,11330861 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05754107 0,11321168 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,05754107 0,11311492 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05754107 0,11301832 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,05754107 0,11292189 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05754107 0,11282562 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05754107 0,11272952 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05754107 0,11263358 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,05754107 0,1125378 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05754107 0,11244219 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,05754107 0,11234674 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05754107 0,11225145 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05754107 0,11215632 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05754107 0,11206135 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05754107 0,11196655 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05754107 0,1118719 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,05754107 0,11177741 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05754107 0,11168309 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05754107 0,11158892 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,05754107 0,11149491 ! macrophage activation GO:0042116 12 8 0,000 0,05754107 0,11140106 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05754107 0,11130736 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05754107 0,11121383 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,05754107 0,11112045 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,05754107 0,11102723 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05754107 0,11093416 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,05754107 0,11084125 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05754107 0,1107485 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05754107 0,1106559 ! ruffle organization GO:0031529 11 8 0,000 0,05754107 0,11056346 ! osteoblast development GO:0002076 13 8 0,000 0,05754107 0,11047117 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05754107 0,11037903 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,05754107 0,11028705 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05754107 0,11019522 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,05754107 0,11010354 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,05754107 0,11001202 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,05754107 0,10992065 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05754107 0,10982942 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05754107 0,10973836 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05754107 0,10964744 ! brain morphogenesis GO:0048854 20 8 0,000 0,05754107 0,10955667 ! oligodendrocyte development GO:0014003 8 8 0,000 0,05754107 0,10946605 ! segment specification GO:0007379 10 8 0,000 0,05754107 0,10937558 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,05754107 0,10928527 ! cellular extravasation GO:0045123 11 8 0,000 0,05754107 0,1091951 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05754107 0,10910508 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05754107 0,1090152 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05754107 0,10892548 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05754107 0,1088359 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,05754107 0,10874647 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,05754107 0,10865719 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,05754107 0,10856805 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05754107 0,10847906 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05754107 0,10839022 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,05754107 0,10830152 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05754107 0,10821297 ! icosanoid secretion GO:0032309 12 8 0,000 0,05754107 0,10812456 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,05754107 0,10803629 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05754107 0,10794817 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05754107 0,10786019 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05754107 0,10777236 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05754107 0,10768467 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05754107 0,10759712 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,05754107 0,10750971 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05754107 0,10742245 ! sterol catabolic process GO:0016127 9 8 0,000 0,05754107 0,10733533 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05754107 0,10724834 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,05754107 0,1071615 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05754107 0,1070748 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,05754107 0,10698824 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05754107 0,10690182 ! prophase GO:0051324 11 8 0,000 0,05754107 0,10681554 ! S phase GO:0051320 8 8 0,000 0,05754107 0,1067294 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,05754107 0,1066434 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,05754107 0,10655753 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05754107 0,10647181 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05754107 0,10638622 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05754107 0,10630077 ! hormone catabolic process GO:0042447 13 8 0,000 0,05754107 0,10621545 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05754107 0,10613028 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,05754107 0,10604524 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05754107 0,10596033 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05754107 0,10587557 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05754107 0,10579093 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05754107 0,10570644 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05754107 0,10562207 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05754107 0,10553784 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05754107 0,10545375 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05754107 0,10536979 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05754107 0,10528596 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05754107 0,10520227 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,05754107 0,10511871 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,05754107 0,10503528 ! single fertilization GO:0007338 59 53 1,000 0,05833164 0,10639395 ! cell projection assembly GO:0030031 76 53 1,000 0,05833164 0,10630964 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,06029048 0,10979265 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,06449867 0,11736309 ! telencephalon cell migration GO:0022029 16 9 0,000 0,06449867 0,11727032 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,06449867 0,11717769 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,06449867 0,1170852 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,06449867 0,11699286 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,06449867 0,11690067 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06449867 0,11680862 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,06449867 0,11671672 ! GTP metabolic process GO:0046039 9 9 0,000 0,06449867 0,11662496 ! elastic fiber assembly GO:0048251 13 9 0,000 0,06449867 0,11653335 ! social behavior GO:0035176 14 9 0,000 0,06449867 0,11644188 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,06449867 0,11635055 ! artery development GO:0060840 19 9 0,000 0,06449867 0,11625937 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,06449867 0,11616832 ! response to pain GO:0048265 16 9 0,000 0,06449867 0,11607743 ! protein complex disassembly GO:0043241 17 9 0,000 0,06449867 0,11598667 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,06449867 0,11589605 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,06449867 0,11580558 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,06449867 0,11571525 ! lung alveolus development GO:0048286 17 9 0,000 0,06449867 0,11562506 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,06449867 0,11553501 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,06449867 0,1154451 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,06449867 0,11535533 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,06449867 0,1152657 ! ventral spinal cord development GO:0021517 11 9 0,000 0,06449867 0,1151762 ! protein targeting to ER GO:0045047 19 9 0,000 0,06449867 0,11508685 ! endoderm development GO:0007492 12 9 0,000 0,06449867 0,11499764 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,06449867 0,11490856 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,06449867 0,11481962 ! arginine catabolic process GO:0006527 10 9 0,000 0,06449867 0,11473082 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,06449867 0,11464216 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,06449867 0,11455363 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,06449867 0,11446524 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06449867 0,11437699 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,06449867 0,11428887 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,06449867 0,11420089 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,06449867 0,11411304 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,06449867 0,11402533 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06449867 0,11393775 ! mannose metabolic process GO:0006013 9 9 0,000 0,06449867 0,11385031 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,06449867 0,113763 ! receptor clustering GO:0043113 15 9 0,000 0,06449867 0,11367582 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,06449867 0,11358878 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,06449867 0,11350187 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,06449867 0,1134151 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,06449867 0,11332846 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,06449867 0,11324195 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,06449867 0,11315557 ! blastoderm segmentation GO:0007350 11 9 0,000 0,06449867 0,11306932 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,06449867 0,11298321 ! DNA ligation GO:0006266 14 9 0,000 0,06449867 0,11289722 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,06449867 0,11281137 ! response to amine stimulus GO:0014075 13 9 0,000 0,06449867 0,11272565 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,06449867 0,11264005 ! erythrocyte development GO:0048821 11 9 0,000 0,06449867 0,11255459 ! renal water homeostasis GO:0003091 14 9 0,000 0,06449867 0,11246926 ! postreplication repair GO:0006301 11 9 0,000 0,06449867 0,11238405 ! mRNA cleavage GO:0006379 13 9 0,000 0,06449867 0,11229898 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,06449867 0,11221403 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,06449867 0,11212921 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,06449867 0,11204452 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,06449867 0,11195996 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,06449867 0,11187553 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,06449867 0,11179122 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,06449867 0,11170704 ! acid secretion GO:0046717 14 9 0,000 0,06449867 0,11162299 ! musculoskeletal movement GO:0050881 11 9 0,000 0,06449867 0,11153906 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,06449867 0,11145526 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,06449867 0,11137158 ! purine base metabolic process GO:0006144 18 9 0,000 0,06449867 0,11128803 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,06449867 0,11120461 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,06449867 0,11112131 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,06449867 0,11103814 ! detection of calcium ion GO:0005513 13 9 0,000 0,06449867 0,11095509 ! blastocyst formation GO:0001825 12 9 0,000 0,06449867 0,11087216 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,06449867 0,11078936 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,06449867 0,11070668 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,06449867 0,11062412 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,06449867 0,11054169 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06449867 0,11045938 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,06449867 0,11037719 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,06449867 0,11029513 ! prepulse inhibition GO:0060134 14 9 0,000 0,06449867 0,11021319 ! embryonic placenta development GO:0001892 12 9 0,000 0,06449867 0,11013137 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,06449867 0,11004967 ! insulin secretion GO:0030073 17 9 0,000 0,06449867 0,10996809 ! establishment of cell polarity GO:0030010 12 9 0,000 0,06449867 0,10988663 ! nucleus localization GO:0051647 15 9 0,000 0,06449867 0,10980529 ! regulation of synapse organization GO:0050807 12 9 0,000 0,06449867 0,10972408 ! carbohydrate transport GO:0008643 74 57 1,000 0,06629979 0,11270474 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,06629979 0,1126215 GO:0048609|reproductive process in a multicellular organism, ! camera-type eye development GO:0043010 88 57 1,000 0,06629979 0,11253838 ! secondary metabolic process GO:0019748 84 57 1,000 0,06629979 0,11245539 ! viral reproductive process GO:0022415 87 58 1,000 0,06834572 0,11584021 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,06834572 0,11575491 ! activation of MAPK activity GO:0000187 84 59 1,000 0,07041238 0,11916738 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,07041238 0,11907976 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07140531 0,12067025 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07140531 0,12058166 ! neuron fate specification GO:0048665 11 10 0,000 0,07140531 0,12049319 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07140531 0,12040485 ! thyroid gland development GO:0030878 19 10 0,000 0,07140531 0,12031664 ! synapsis GO:0007129 13 10 0,000 0,07140531 0,12022856 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07140531 0,12014061 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,07140531 0,12005279 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07140531 0,1199651 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,07140531 0,11987753 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07140531 0,11979009 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,07140531 0,11970278 ! androgen metabolic process GO:0008209 13 10 0,000 0,07140531 0,1196156 ! phospholipid efflux GO:0033700 16 10 0,000 0,07140531 0,11952854 ! hippocampus development GO:0021766 19 10 0,000 0,07140531 0,11944161 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,07140531 0,11935481 ! blood vessel remodeling GO:0001974 21 10 0,000 0,07140531 0,11926813 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07140531 0,11918158 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07140531 0,11909515 ! pathogenesis GO:0009405 13 10 0,000 0,07140531 0,11900885 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07140531 0,11892268 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07140531 0,11883662 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07140531 0,1187507 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,07140531 0,1186649 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,07140531 0,11857922 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07140531 0,11849366 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07140531 0,11840823 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07140531 0,11832292 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07140531 0,11823774 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07140531 0,11815267 ! response to X-ray GO:0010165 16 10 0,000 0,07140531 0,11806773 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07140531 0,11798291 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07140531 0,11789822 ! forebrain cell migration GO:0021885 17 10 0,000 0,07140531 0,11781364 ! lipid digestion GO:0044241 15 10 0,000 0,07140531 0,11772919 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07140531 0,11764485 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,07140531 0,11756064 ! UV protection GO:0009650 14 10 0,000 0,07140531 0,11747655 ! entry into host cell GO:0030260 20 10 0,000 0,07140531 0,11739258 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07140531 0,11730873 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07140531 0,11722499 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,07140531 0,11714138 ! regulation of bone resorption GO:0045124 24 10 0,000 0,07140531 0,11705789 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07140531 0,11697451 ! regulation of organ growth GO:0046620 11 10 0,000 0,07140531 0,11689126 ! response to dsRNA GO:0043331 18 10 0,000 0,07140531 0,11680812 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07140531 0,1167251 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07140531 0,1166422 ! embryonic axis specification GO:0000578 12 10 0,000 0,07140531 0,11655941 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07140531 0,11647675 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,07140531 0,1163942 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,07140531 0,11631177 ! cranial nerve development GO:0021545 12 10 0,000 0,07140531 0,11622945 ! fucose catabolic process GO:0019317 16 10 0,000 0,07140531 0,11614725 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,07140531 0,11606517 ! protein sumoylation GO:0016925 12 10 0,000 0,07140531 0,1159832 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07140531 0,11590135 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07140531 0,11581962 ! zymogen activation GO:0031638 14 10 0,000 0,07140531 0,115738 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07140531 0,11565649 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07140531 0,1155751 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,07140531 0,11549382 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07140531 0,11541266 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,07140531 0,11533161 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07140531 0,11525068 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07140531 0,11516986 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07140531 0,11508915 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,07140531 0,11500855 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07140531 0,11492807 ! detection of bacterium GO:0016045 10 10 0,000 0,07140531 0,1148477 ! embryonic gut development GO:0048566 11 10 0,000 0,07140531 0,11476745 ! activation of innate immune response GO:0002218 10 10 0,000 0,07140531 0,1146873 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07140531 0,11460727 ! developmental induction GO:0031128 13 10 0,000 0,07140531 0,11452735 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07140531 0,11444754 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,07140531 0,11436784 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,07140531 0,11428825 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07140531 0,11420877 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,07249935 0,11587804 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,07249935 0,11579757 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 1,000 0,07249935 0,11571721 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,07249935 0,11563696 ! fertilization GO:0009566 68 60 1,000 0,07249935 0,11555682 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,07460621 0,11883261 ! homeostasis of number of cells GO:0048872 84 61 1,000 0,07460621 0,11875037 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,07673258 0,12205043 ! organelle localization GO:0051640 96 62 1,000 0,07673258 0,12196609 ! rRNA transcription GO:0009303 17 11 0,000 0,07826135 0,12431016 ! respiratory burst GO:0045730 14 11 0,000 0,07826135 0,12422437 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07826135 0,12413869 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07826135 0,12405314 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,07826135 0,1239677 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,07826135 0,12388238 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07826135 0,12379718 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07826135 0,1237121 ! mating GO:0007618 14 11 0,000 0,07826135 0,12362713 ! T cell proliferation GO:0042098 20 11 0,000 0,07826135 0,12354228 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,07826135 0,12345755 ! bone resorption GO:0045453 16 11 0,000 0,07826135 0,12337293 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07826135 0,12328843 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07826135 0,12320404 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,07826135 0,12311977 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,07826135 0,12303562 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07826135 0,12295157 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,07826135 0,12286765 ! syncytium formation GO:0006949 15 11 0,000 0,07826135 0,12278384 ! plasma membrane organization GO:0007009 18 11 0,000 0,07826135 0,12270014 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,07826135 0,12261656 ! mitotic spindle organization GO:0007052 15 11 0,000 0,07826135 0,12253309 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,07826135 0,12244973 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,07826135 0,12236649 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,07826135 0,12228336 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07826135 0,12220034 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,07826135 0,12211744 ! temperature homeostasis GO:0001659 16 11 0,000 0,07826135 0,12203465 ! L-glutamate transport GO:0015813 16 11 0,000 0,07826135 0,12195197 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,07826135 0,1218694 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07826135 0,12178695 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07826135 0,1217046 ! stem cell development GO:0048864 29 11 0,000 0,07826135 0,12162237 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,07826135 0,12154025 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07826135 0,12145824 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07826135 0,12137634 ! vasoconstriction GO:0042310 15 11 0,000 0,07826135 0,12129455 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,07826135 0,12121287 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07826135 0,1211313 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07826135 0,12104984 ! ribosome assembly GO:0042255 13 11 0,000 0,07826135 0,12096848 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,07826135 0,12088724 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,07826135 0,12080611 ! chromatin silencing GO:0006342 19 11 0,000 0,07826135 0,12072509 ! nucleosome positioning GO:0016584 13 11 0,000 0,07826135 0,12064417 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07826135 0,12056337 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,07826135 0,12048267 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07826135 0,12040208 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07826135 0,12032159 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,07826135 0,12024122 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,07826135 0,12016095 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,07826135 0,12008079 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,07826135 0,12000074 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,07826135 0,11992079 ! male genitalia development GO:0030539 13 11 0,000 0,07826135 0,11984095 ! cholesterol efflux GO:0033344 19 11 0,000 0,07826135 0,11976121 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07826135 0,11968159 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,07826135 0,11960206 ! germ cell migration GO:0008354 18 11 0,000 0,07826135 0,11952265 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,07826135 0,11944333 ! defense response to fungus GO:0050832 12 11 0,000 0,07826135 0,11936413 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07826135 0,11928503 ! lysogeny GO:0030069 18 11 0,000 0,07826135 0,11920603 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07826135 0,11912714 ! acrosome reaction GO:0007340 13 11 0,000 0,07826135 0,11904835 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07826135 0,11896967 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,07887804 0,11982794 ! viral reproduction GO:0016032 92 63 1,000 0,07887804 0,11974885 ! B cell activation GO:0042113 104 65 1,000 0,08322472 0,12626442 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,08322472 0,12618118 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,08322472 0,12609806 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,08322472 0,12601505 ! lactation GO:0007595 20 12 0,000 0,08506716 0,12872004 ! reproductive cellular process GO:0048610 14 12 0,000 0,08506716 0,12863541 ! tRNA modification GO:0006400 14 12 0,000 0,08506716 0,1285509 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,08506716 0,12846649 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,08506716 0,1283822 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,08506716 0,12829801 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,08506716 0,12821394 ! non-recombinational repair GO:0000726 19 12 0,000 0,08506716 0,12812997 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,08506716 0,12804612 ! peroxisomal transport GO:0043574 21 12 0,000 0,08506716 0,12796237 ! cartilage condensation GO:0001502 18 12 0,000 0,08506716 0,12787874 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,08506716 0,12779521 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,08506716 0,12771179 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,08506716 0,12762848 ! heart looping GO:0001947 15 12 0,000 0,08506716 0,12754528 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,08506716 0,12746219 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,08506716 0,12737921 ! arginine metabolic process GO:0006525 13 12 0,000 0,08506716 0,12729633 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,08506716 0,12721357 ! methionine metabolic process GO:0006555 13 12 0,000 0,08506716 0,12713091 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,08506716 0,12704835 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,08506716 0,12696591 ! monoamine transport GO:0015844 13 12 0,000 0,08506716 0,12688357 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08506716 0,12680134 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,08506716 0,12671921 ! L-amino acid transport GO:0015807 20 12 0,000 0,08506716 0,12663719 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,08506716 0,12655528 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,08506716 0,12647347 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,08506716 0,12639177 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08506716 0,12631018 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,08506716 0,12622869 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,08506716 0,1261473 ! cerebellum development GO:0021549 13 12 0,000 0,08506716 0,12606602 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,08506716 0,12598485 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,08506716 0,12590377 ! histone methylation GO:0016571 15 12 0,000 0,08506716 0,12582281 ! autonomic nervous system development GO:0048483 23 12 0,000 0,08506716 0,12574194 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,08506716 0,12566119 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,08506716 0,12558053 ! intestinal absorption GO:0050892 19 12 0,000 0,08506716 0,12549998 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,08506716 0,12541953 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,08506716 0,12533918 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,08506716 0,12525894 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,08506716 0,1251788 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,08506716 0,12509876 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,08506716 0,12501883 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,08506716 0,12493899 ! microspike assembly GO:0030035 23 12 0,000 0,08506716 0,12485926 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,08506716 0,12477963 ! response to cold GO:0009409 14 12 0,000 0,08506716 0,12470011 ! antigen processing and presentation GO:0019882 96 66 1,000 0,08542516 0,12514513 ! axon guidance GO:0007411 99 66 1,000 0,08542516 0,12506547 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 1,000 0,08764315 0,12823108 ! learning or memory GO:0007611 123 68 1,000 0,08987834 0,13141779 ! cytosolic calcium ion homeostasis GO:0051480 107 68 1,000 0,08987834 0,13133429 ! rhythmic process GO:0048511 105 68 1,000 0,08987834 0,13125091 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,0918231 0,1340058 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,0918231 0,13392082 ! cGMP metabolic process GO:0046068 16 13 0,000 0,0918231 0,13383595 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,0918231 0,13375119 ! water transport GO:0006833 17 13 0,000 0,0918231 0,13366654 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,0918231 0,133582 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,0918231 0,13349756 ! lipid localization GO:0010876 24 13 0,000 0,0918231 0,13341323 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,0918231 0,133329 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,0918231 0,13324488 ! organelle fusion GO:0048284 28 13 0,000 0,0918231 0,13316087 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,0918231 0,13307696 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,0918231 0,13299316 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,0918231 0,13290946 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,0918231 0,13282587 ! response to hexose stimulus GO:0009746 19 13 0,000 0,0918231 0,13274239 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,0918231 0,13265901 ! glutamate metabolic process GO:0006536 18 13 0,000 0,0918231 0,13257573 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,0918231 0,13249256 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,0918231 0,13240949 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,0918231 0,13232653 ! NAD metabolic process GO:0019674 21 13 0,000 0,0918231 0,13224367 ! bone mineralization GO:0030282 15 13 0,000 0,0918231 0,13216091 ! regulation of exocytosis GO:0017157 17 13 0,000 0,0918231 0,13207826 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,0918231 0,13199571 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,0918231 0,13191326 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,0918231 0,13183092 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,0918231 0,13174868 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,0918231 0,13166654 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,0918231 0,13158451 ! genitalia development GO:0048806 15 13 0,000 0,0918231 0,13150258 ! regulation of cellular pH GO:0030641 20 13 0,000 0,0918231 0,13142074 ! tissue regeneration GO:0042246 21 13 0,000 0,0918231 0,13133901 ! cofactor transport GO:0051181 19 13 0,000 0,0918231 0,13125739 ! NADP metabolic process GO:0006739 18 13 0,000 0,0918231 0,13117586 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,0918231 0,13109444 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,0918231 0,13101311 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0918231 0,13093189 ! gas transport GO:0015669 18 13 0,000 0,0918231 0,13085077 ! regulation of RNA stability GO:0043487 28 13 0,000 0,0918231 0,13076974 ! heme biosynthetic process GO:0006783 20 13 0,000 0,0918231 0,13068882 ! regulation of axon extension GO:0030516 23 13 0,000 0,0918231 0,130608 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,0918231 0,13052728 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,0918231 0,13044666 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,0918231 0,13036613 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,0918231 0,13028571 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,0918231 0,13020539 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,09213034 0,13056055 ! humoral immune response GO:0006959 86 70 1,000 0,09439879 0,13369287 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,09439879 0,1336106 ! regulation of catabolic process GO:0009894 106 70 1,000 0,09439879 0,13352842 ! muscle cell differentiation GO:0042692 104 71 1,000 0,09668333 0,13667588 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,09852954 0,13920022 ! superoxide anion generation GO:0042554 18 14 0,000 0,09852954 0,13911476 ! regulation of S phase GO:0033261 18 14 0,000 0,09852954 0,13902942 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09852954 0,13894418 ! myotube differentiation GO:0014902 21 14 0,000 0,09852954 0,13885904 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,09852954 0,13877401 ! inositol metabolic process GO:0006020 20 14 0,000 0,09852954 0,13868908 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09852954 0,13860425 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09852954 0,13851953 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09852954 0,13843491 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09852954 0,1383504 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09852954 0,13826599 ! response to cAMP GO:0051591 19 14 0,000 0,09852954 0,13818168 ! limbic system development GO:0021761 25 14 0,000 0,09852954 0,13809747 ! startle response GO:0001964 21 14 0,000 0,09852954 0,13801337 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09852954 0,13792937 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,09852954 0,13784547 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,09852954 0,13776167 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,09852954 0,13767798 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,09852954 0,13759438 ! glycine metabolic process GO:0006544 22 14 0,000 0,09852954 0,13751089 ! lysosomal transport GO:0007041 20 14 0,000 0,09852954 0,1374275 ! regulation of heart rate GO:0002027 23 14 0,000 0,09852954 0,13734421 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09852954 0,13726102 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09852954 0,13717794 ! embryo implantation GO:0007566 27 14 0,000 0,09852954 0,13709495 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,09852954 0,13701206 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,09852954 0,13692928 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,09852954 0,13684659 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,09852954 0,136764 ! axon cargo transport GO:0008088 27 14 0,000 0,09852954 0,13668151 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09852954 0,13659913 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,09852954 0,13651684 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09852954 0,13643465 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09852954 0,13635256 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,09852954 0,13627057 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09852954 0,13618867 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,09852954 0,13610688 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09852954 0,13602518 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,09852954 0,13594358 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,09852954 0,13586208 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,09852954 0,13578068 ! muscle maintenance GO:0046716 19 14 0,000 0,09852954 0,13569937 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,09852954 0,13561816 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09852954 0,13553705 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09852954 0,13545604 ! cell killing GO:0001906 20 14 0,000 0,09852954 0,13537512 ! cilium assembly GO:0042384 20 14 0,000 0,09852954 0,1352943 ! peptide hormone secretion GO:0030072 23 14 0,000 0,09852954 0,13521357 ! regulation of blood pressure GO:0008217 107 73 1,000 0,10129927 0,13893161 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,10518684 0,14417744 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,10518684 0,14409156 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,10518684 0,1440058 ! skin development GO:0043588 25 15 0,000 0,10518684 0,14392013 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,10518684 0,14383456 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,10518684 0,1437491 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,10518684 0,14366374 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,10518684 0,14357848 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,10518684 0,14349332 ! bile acid metabolic process GO:0008206 22 15 0,000 0,10518684 0,14340826 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,10518684 0,1433233 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,10518684 0,14323845 ! adult walking behavior GO:0007628 25 15 0,000 0,10518684 0,14315369 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,10518684 0,14306903 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,10518684 0,14298448 ! centrosome cycle GO:0007098 16 15 0,000 0,10518684 0,14290002 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,10518684 0,14281567 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,10518684 0,14273141 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,10518684 0,14264725 ! cerebral cortex development GO:0021987 29 15 0,000 0,10518684 0,14256319 ! response to osmotic stress GO:0006970 22 15 0,000 0,10518684 0,14247923 ! vesicle coating GO:0006901 25 15 0,000 0,10518684 0,14239537 ! DNA integration GO:0015074 22 15 0,000 0,10518684 0,14231161 ! peptide secretion GO:0002790 27 15 0,000 0,10518684 0,14222795 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,10518684 0,14214438 ! neuron recognition GO:0008038 22 15 0,000 0,10518684 0,14206091 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,10518684 0,14197755 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,10518684 0,14189427 ! biomineral formation GO:0031214 18 15 0,000 0,10518684 0,1418111 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,10518684 0,14172802 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,10518684 0,14164505 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,10518684 0,14156216 ! organic cation transport GO:0015695 19 15 0,000 0,10518684 0,14147938 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,10518684 0,14139669 GO:0033014|tetrapyrrole biosynthetic process, ! peptide hormone processing GO:0016486 19 15 0,000 0,10518684 0,1413141 ! response to nutrient GO:0007584 104 75 1,000 0,10597534 0,1422903 ! amine biosynthetic process GO:0009309 97 76 1,000 0,10833508 0,14537379 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,10833508 0,14528903 ! regulation of protein transport GO:0051223 114 76 1,000 0,10833508 0,14520436 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,11070883 0,14829954 ! cholesterol metabolic process GO:0008203 109 77 1,000 0,11070883 0,14821322 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,11070883 0,148127 ! protein secretion GO:0009306 27 16 0,000 0,11179536 0,14949379 ! hormone secretion GO:0046879 25 16 0,000 0,11179536 0,14940692 ! bone remodeling GO:0046849 24 16 0,000 0,11179536 0,14932016 ! endothelial cell migration GO:0043542 22 16 0,000 0,11179536 0,1492335 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,11179536 0,14914694 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,11179536 0,14906047 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,11179536 0,14897411 ! glial cell development GO:0021782 24 16 0,000 0,11179536 0,14888785 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,11179536 0,14880169 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,11179536 0,14871563 ! protein polyubiquitination GO:0000209 26 16 0,000 0,11179536 0,14862966 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,11179536 0,1485438 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,11179536 0,14845804 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,11179536 0,14837237 ! fructose metabolic process GO:0006000 20 16 0,000 0,11179536 0,1482868 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,11179536 0,14820134 ! DNA replication initiation GO:0006270 25 16 0,000 0,11179536 0,14811597 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,11179536 0,14803069 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,11179536 0,14794552 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,11179536 0,14786045 ! neural crest cell migration GO:0001755 24 16 0,000 0,11179536 0,14777547 ! G1 phase GO:0051318 27 16 0,000 0,11179536 0,14769059 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,11179536 0,14760581 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,11179536 0,14752112 ! steroid catabolic process GO:0006706 22 16 0,000 0,11179536 0,14743653 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,11179536 0,14735204 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,11179536 0,14726765 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,11179536 0,14718335 ! sperm-egg recognition GO:0035036 16 16 0,000 0,11179536 0,14709915 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,11179536 0,14701505 ! nerve development GO:0021675 18 16 0,000 0,11179536 0,14693104 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,11179536 0,14684713 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,11179536 0,14676331 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,11309627 0,14838643 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,11549706 0,15144997 ! cellular respiration GO:0045333 107 79 1,000 0,11549706 0,15136367 ! regulation of lyase activity GO:0051339 133 79 1,000 0,11549706 0,15127747 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,11835544 0,15493313 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,11835544 0,154845 ! negative regulation of defense response GO:0031348 19 17 0,000 0,11835544 0,15475697 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,11835544 0,15466904 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,11835544 0,15458121 ! glycerol metabolic process GO:0006071 20 17 0,000 0,11835544 0,15449348 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,11835544 0,15440585 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,11835544 0,15431831 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,11835544 0,15423088 ! signal complex assembly GO:0007172 29 17 0,000 0,11835544 0,15414355 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,11835544 0,15405631 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,11835544 0,15396918 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,11835544 0,15388214 ! memory GO:0007613 25 17 0,000 0,11835544 0,1537952 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,11835544 0,15370836 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,11835544 0,15362162 ! retinoid metabolic process GO:0001523 22 17 0,000 0,11835544 0,15353497 GO:0016101|diterpenoid metabolic process, ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,11835544 0,15344843 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,11835544 0,15336198 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,11835544 0,15327562 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,11835544 0,15318937 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,11835544 0,15310321 ! membrane budding GO:0006900 29 17 0,000 0,11835544 0,15301715 ! heme metabolic process GO:0042168 27 17 0,000 0,11835544 0,15293118 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,11835544 0,15284532 ! body fluid secretion GO:0007589 27 17 0,000 0,11835544 0,15275954 ! stem cell differentiation GO:0048863 36 17 0,000 0,11835544 0,15267387 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,11835544 0,15258829 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,11835544 0,1525028 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,11835544 0,15241742 ! sensory perception of pain GO:0019233 23 17 0,000 0,11835544 0,15233212 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,11835544 0,15224693 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,11835544 0,15216183 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,11835544 0,15207682 ! synaptogenesis GO:0007416 24 17 0,000 0,11835544 0,15199191 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,11835544 0,15190709 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,11835544 0,15182237 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,11835544 0,15173774 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,11835544 0,15165321 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,11835544 0,15156877 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,11835544 0,15148442 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,12033744 0,15393554 ! response to protein stimulus GO:0051789 111 81 1,000 0,12033744 0,15384997 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,12486744 0,15955284 ! positive regulation of translation GO:0045727 28 18 0,000 0,12486744 0,15946425 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,12486744 0,15937576 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,12486744 0,15928736 ! cAMP metabolic process GO:0046058 33 18 0,000 0,12486744 0,15919907 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,12486744 0,15911087 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,12486744 0,15902277 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,12486744 0,15893476 ! axis specification GO:0009798 26 18 0,000 0,12486744 0,15884686 ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,12486744 0,15875905 ! pancreas development GO:0031016 26 18 0,000 0,12486744 0,15867133 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,12486744 0,15858372 ! glutamine metabolic process GO:0006541 23 18 0,000 0,12486744 0,1584962 ! response to retinoic acid GO:0032526 25 18 0,000 0,12486744 0,15840878 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,12486744 0,15832145 ! fucose metabolic process GO:0006004 26 18 0,000 0,12486744 0,15823422 ! response to fungus GO:0009620 19 18 0,000 0,12486744 0,15814709 ! peptide cross-linking GO:0018149 31 18 0,000 0,12486744 0,15806005 ! heart process GO:0003015 27 18 0,000 0,12486744 0,15797311 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,12486744 0,15788626 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 35 18 0,000 0,12486744 0,15779951 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,12486744 0,15771286 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,12486744 0,1576263 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,12486744 0,15753983 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,12486744 0,15745346 ! vitamin transport GO:0051180 24 18 0,000 0,12486744 0,15736719 ! hormone transport GO:0009914 27 18 0,000 0,12486744 0,15728101 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,12486744 0,15719492 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,12486744 0,15710893 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,12486744 0,15702303 ! cell-cell recognition GO:0009988 20 18 0,000 0,12486744 0,15693722 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,12486744 0,15685151 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,12486744 0,15676589 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,12486744 0,15668037 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,12522742 0,15704638 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,12522742 0,15696079 ! sterol metabolic process GO:0016125 120 84 1,000 0,12769023 0,15996053 ! Golgi vesicle transport GO:0048193 138 85 1,000 0,13016453 0,16297137 ! rRNA metabolic process GO:0016072 107 85 1,000 0,13016453 0,1628827 GO:0006364|rRNA processing, ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,13016453 0,16279413 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,13016453 0,16270566 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,13133172 0,16407547 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,13133172 0,1639864 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,13133172 0,16389742 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,13133172 0,16380854 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,13133172 0,16371976 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,13133172 0,16363107 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,13133172 0,16354247 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,13133172 0,16345398 ! sensory perception of taste GO:0050909 23 19 0,000 0,13133172 0,16336558 ! smooth muscle contraction GO:0006939 36 19 0,000 0,13133172 0,16327727 ! peroxisome organization GO:0007031 29 19 0,000 0,13133172 0,16318906 ! digestive system process GO:0022600 30 19 0,000 0,13133172 0,16310094 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,13133172 0,16301292 ! response to vitamin A GO:0033189 26 19 0,000 0,13133172 0,162925 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,13133172 0,16283717 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,13133172 0,16274943 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,13133172 0,16266179 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,13133172 0,16257425 ! cytolysis GO:0019835 20 19 0,000 0,13133172 0,16248679 ! vasodilation GO:0042311 33 19 0,000 0,13133172 0,16239943 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,13133172 0,16231217 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,13133172 0,162225 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,13133172 0,16213792 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,13133172 0,16205094 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,13133172 0,16196405 ! sarcomere organization GO:0045214 23 19 0,000 0,13133172 0,16187725 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,13133172 0,16179055 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,13133172 0,16170393 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,13133172 0,16161741 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,13133172 0,16153099 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,13133172 0,16144465 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,13133172 0,16135841 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,13133172 0,16127226 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,13265 0,16280416 ! female pregnancy GO:0007565 130 87 1,000 0,13514635 0,16577953 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,1376533 0,1687647 ! protein processing GO:0016485 114 88 1,000 0,1376533 0,16867479 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,13774861 0,16870171 ! iron ion transport GO:0006826 37 20 0,000 0,13774861 0,16861192 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,13774861 0,16852224 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,13774861 0,16843264 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,13774861 0,16834315 ! response to vitamin GO:0033273 29 20 0,000 0,13774861 0,16825375 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,13774861 0,16816444 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,13774861 0,16807523 ! spinal cord development GO:0021510 31 20 0,000 0,13774861 0,16798611 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,13774861 0,16789709 ! chromosome condensation GO:0030261 31 20 0,000 0,13774861 0,16780816 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,13774861 0,16771932 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,13774861 0,16763058 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,13774861 0,16754194 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,13774861 0,16745338 ! pallium development GO:0021543 38 20 0,000 0,13774861 0,16736492 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,13774861 0,16727656 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,13774861 0,16718829 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,13774861 0,16710011 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,13774861 0,16701202 ! alditol metabolic process GO:0019400 24 20 0,000 0,13774861 0,16692403 ! actin filament-based movement GO:0030048 34 20 0,000 0,13774861 0,16683613 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,14017054 0,16968013 ! hormone metabolic process GO:0042445 121 90 1,000 0,1426978 0,17264858 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,14411847 0,17427575 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,14411847 0,17418417 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,14411847 0,17409269 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,14411847 0,1740013 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,14411847 0,17391001 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,14411847 0,17381881 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,14411847 0,17372771 ! vesicle docking GO:0048278 27 21 0,000 0,14411847 0,17363671 ! phototransduction GO:0007602 25 21 0,000 0,14411847 0,1735458 ! visual behavior GO:0007632 39 21 0,000 0,14411847 0,17345498 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,14411847 0,17336426 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,14411847 0,17327364 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,14411847 0,17318311 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,14411847 0,17309267 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,14411847 0,17300233 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,14411847 0,17291209 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,14411847 0,17282194 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,14411847 0,17273188 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,14411847 0,17264191 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,14411847 0,17255204 ! fatty acid transport GO:0015908 30 21 0,000 0,14411847 0,17246226 ! immunoglobulin production GO:0002377 33 21 0,000 0,14411847 0,17237258 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,14411847 0,17228299 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,14411847 0,17219349 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,14411847 0,17210409 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,14411847 0,17201478 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,14411847 0,17192556 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,14411847 0,17183643 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,14411847 0,17174739 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,14411847 0,17165845 ! response to virus GO:0009615 122 91 1,000 0,1452348 0,17289857 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,14778125 0,17583904 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,14778125 0,17574812 ! positive regulation of immune response GO:0050778 121 92 1,000 0,14778125 0,1756573 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,15033688 0,1786027 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,15033688 0,1785105 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,15044163 0,1785427 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,15044163 0,17845062 ! viral genome replication GO:0019079 29 22 0,000 0,15044163 0,17835863 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,15044163 0,17826674 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,15044163 0,17817494 ! leukocyte adhesion GO:0007159 38 22 0,000 0,15044163 0,17808324 ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,15044163 0,17799164 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,15044163 0,17790012 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,15044163 0,17780871 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,15044163 0,17771738 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,15044163 0,17762615 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,15044163 0,17753501 ! lysosome organization GO:0007040 37 22 0,000 0,15044163 0,17744397 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,15044163 0,17735302 GO:0051693|actin filament capping, ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,15044163 0,17726216 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,15044163 0,1771714 ! membrane depolarization GO:0051899 35 22 0,000 0,15044163 0,17708073 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,15044163 0,17699015 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,15044163 0,17689966 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,15044163 0,17680927 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,15044163 0,17671897 ! blastocyst development GO:0001824 37 22 0,000 0,15044163 0,17662876 ! neural tube closure GO:0001843 33 22 0,000 0,15044163 0,17653864 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,15044163 0,17644862 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,15671843 0,18371682 ! neuron fate commitment GO:0048663 32 23 0,000 0,15671843 0,18362323 ! embryonic pattern specification GO:0009880 31 23 0,000 0,15671843 0,18352973 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,15671843 0,18343633 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,15671843 0,18334303 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,15671843 0,18324982 ! vesicle targeting GO:0006903 32 23 0,000 0,15671843 0,18315671 ! osteoblast differentiation GO:0001649 40 23 0,000 0,15671843 0,18306369 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,15671843 0,18297076 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,15671843 0,18287793 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,15671843 0,18278519 ! cell fate determination GO:0001709 45 23 0,000 0,15671843 0,18269255 ! pentose metabolic process GO:0019321 31 23 0,000 0,15671843 0,1826 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,15671843 0,18250754 ! spermatid development GO:0007286 33 23 0,000 0,15671843 0,18241518 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,15671843 0,18232291 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,15671843 0,18223074 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,15671843 0,18213865 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,15671843 0,18204666 ! telomere organization GO:0032200 32 23 0,000 0,15671843 0,18195477 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,15671843 0,18186296 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,15671843 0,18177125 ! regulation of amine transport GO:0051952 38 23 0,000 0,15671843 0,18167964 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,16294922 0,18880766 ! initiation of viral infection GO:0019059 42 24 0,000 0,16294922 0,18871259 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,16294922 0,18861762 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,16294922 0,18852274 ! superoxide metabolic process GO:0006801 32 24 0,000 0,16294922 0,18842796 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,16294922 0,18833327 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,16294922 0,18823868 ! fat cell differentiation GO:0045444 37 24 0,000 0,16294922 0,18814418 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,16294922 0,18804978 ! sperm motility GO:0030317 27 24 0,000 0,16294922 0,18795547 ! vacuole organization GO:0007033 39 24 0,000 0,16294922 0,18786126 ! receptor metabolic process GO:0043112 37 24 0,000 0,16294922 0,18776714 ! neural crest cell development GO:0014032 39 24 0,000 0,16294922 0,18767311 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,16294922 0,18757918 ! negative regulation of cell development GO:0010721 56 24 0,000 0,16294922 0,18748535 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 0,000 0,16294922 0,1873916 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,16294922 0,18729796 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,16294922 0,1872044 ! glutathione metabolic process GO:0006749 29 24 0,000 0,16294922 0,18711094 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,16294922 0,18701757 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,16294922 0,18692429 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,16846107 0,19315078 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,16846107 0,19305454 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,16913433 0,19372956 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,16913433 0,19363312 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,16913433 0,19353679 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,16913433 0,19344055 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,16913433 0,19334441 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,16913433 0,19324836 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,16913433 0,19315241 ! peptide transport GO:0015833 43 25 0,000 0,16913433 0,19305655 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,16913433 0,19296079 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,16913433 0,19286512 ! phospholipid transport GO:0015914 35 25 0,000 0,16913433 0,19276955 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,16913433 0,19267407 ! detection of light stimulus GO:0009583 30 25 0,000 0,16913433 0,19257869 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,17527408 0,19947075 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,17527408 0,1993721 ! translational initiation GO:0006413 43 26 0,000 0,17527408 0,19927354 ! regulation of pH GO:0006885 36 26 0,000 0,17527408 0,19917509 ! circadian rhythm GO:0007623 42 26 0,000 0,17527408 0,19907673 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,17527408 0,19897847 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,17527408 0,19888031 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,17527408 0,19878224 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,17527408 0,19868427 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,17527408 0,19858639 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,17527408 0,19848862 ! regulation of coagulation GO:0050818 39 26 0,000 0,17527408 0,19839094 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,18136881 0,20518852 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,18136881 0,20508764 ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,18136881 0,20498686 ! membrane docking GO:0022406 39 27 0,000 0,18136881 0,20488618 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,18136881 0,2047856 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,18136881 0,20468511 ! acute-phase response GO:0006953 42 27 0,000 0,18136881 0,20458473 ! myofibril assembly GO:0030239 36 27 0,000 0,18136881 0,20448444 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,18136881 0,20438425 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,18136881 0,20428416 ! natural killer cell activation GO:0030101 35 27 0,000 0,18136881 0,20418417 ! lipid oxidation GO:0034440 38 27 0,000 0,18136881 0,20408428 GO:0019395|fatty acid oxidation, ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,18136881 0,20398448 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,18136881 0,20388478 ! gene silencing GO:0016458 41 27 0,000 0,18136881 0,20378518 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,18741885 0,21048015 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,18741885 0,21037743 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,18741885 0,21027481 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,18741885 0,21017228 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,18741885 0,21006986 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,18741885 0,20996754 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,18741885 0,20986531 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,18741885 0,20976319 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,18741885 0,20966116 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,18741885 0,20955924 GO:0002764|immune response-regulating signal transduction, ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,18741885 0,20945741 ! mesoderm formation GO:0001707 46 28 0,000 0,18741885 0,20935568 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,18741885 0,20925405 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,18741885 0,20915252 ! neural tube formation GO:0001841 41 28 0,000 0,18741885 0,20905109 ! regulation of innate immune response GO:0045088 38 29 0,000 0,19342452 0,21564537 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,19342452 0,21554089 ! protein targeting to membrane GO:0006612 53 29 0,000 0,19342452 0,21543651 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,19342452 0,21533223 ! mismatch repair GO:0006298 34 29 0,000 0,19342452 0,21522806 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,19342452 0,21512398 ! muscle cell development GO:0055001 38 29 0,000 0,19342452 0,21502001 ! formation of primary germ layer GO:0001704 48 29 0,000 0,19342452 0,21491613 ! telencephalon development GO:0021537 52 29 0,000 0,19342452 0,21481236 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,19342452 0,21470868 ! eye morphogenesis GO:0048592 51 29 0,000 0,19342452 0,21460511 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,19342452 0,21450164 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,19938614 0,22100633 ! organic anion transport GO:0015711 51 30 0,000 0,19938614 0,22089987 ! cholesterol transport GO:0030301 46 30 0,000 0,19938614 0,22079352 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,19938614 0,22068726 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,19938614 0,22058111 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,19938614 0,22047506 ! ceramide metabolic process GO:0006672 43 30 0,000 0,19938614 0,22036912 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,19938614 0,22026327 ! adult locomotory behavior GO:0008344 47 30 0,000 0,19938614 0,22015753 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,19938614 0,22005189 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,19938614 0,21994635 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,19938614 0,21984091 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,20530404 0,22625745 ! negative regulation of secretion GO:0051048 49 31 0,000 0,20530404 0,22614909 ! glial cell differentiation GO:0010001 55 31 0,000 0,20530404 0,22604083 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,20530404 0,22593268 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,20530404 0,22582463 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,20530404 0,22571668 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,20530404 0,22560884 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,20530404 0,2255011 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,20530404 0,22539346 ! cell fate specification GO:0001708 37 31 0,000 0,20530404 0,22528593 ! RNA modification GO:0009451 40 31 0,000 0,20530404 0,22517849 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,21117854 0,23151127 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,21117854 0,23140097 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,21117854 0,23129078 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,21117854 0,23118069 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,21117854 0,23107071 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,21117854 0,23096083 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,21117854 0,23085106 ! vesicle localization GO:0051648 47 32 0,000 0,21117854 0,23074139 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,21700994 0,23700041 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,21700994 0,23688793 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,21700994 0,23677555 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,21700994 0,23666328 ! actomyosin structure organization GO:0031032 43 33 0,000 0,21700994 0,23655112 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,21700994 0,23643906 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,21700994 0,23632711 ! regulation of proteolysis GO:0030162 50 33 0,000 0,21700994 0,23621527 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,21700994 0,23610353 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,21700994 0,2359919 ! mRNA catabolic process GO:0006402 48 34 0,000 0,22279856 0,24217235 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,22279856 0,24205796 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,22279856 0,24194367 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,22279856 0,24182949 ! feeding behavior GO:0007631 45 34 0,000 0,22279856 0,24171542 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,22279856 0,24160146 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,22279856 0,2414876 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,22279856 0,24137386 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,22279856 0,24126022 ! polyol metabolic process GO:0019751 44 34 0,000 0,22279856 0,24114668 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,22279856 0,24103325 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,22854472 0,24713346 ! Notch signaling pathway GO:0007219 56 35 0,000 0,22854472 0,24701732 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,22854472 0,2469013 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,22854472 0,24678538 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,22854472 0,24666957 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,22854472 0,24655388 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,22854472 0,24643829 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,22854472 0,2463228 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,23424873 0,25235226 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,23424873 0,25223411 ! organic ether metabolic process GO:0018904 46 36 0,000 0,23424873 0,25211608 ! tissue remodeling GO:0048771 62 36 0,000 0,23424873 0,25199816 ! neural tube development GO:0021915 50 36 0,000 0,23424873 0,25188035 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,23424873 0,25176265 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,23424873 0,25164506 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,23991088 0,25760739 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,23991088 0,25748718 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,23991088 0,25736708 ! learning GO:0007612 67 37 0,000 0,23991088 0,2572471 ! ion transmembrane transport GO:0034220 56 37 0,000 0,23991088 0,25712722 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,23991088 0,25700746 ! regulation of protein secretion GO:0050708 51 37 0,000 0,23991088 0,25688781 ! amino acid activation GO:0043038 52 37 0,000 0,23991088 0,25676827 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,23991088 0,25664885 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,24553149 0,26253948 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,24553149 0,26241748 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,24553149 0,2622956 ! phagocytosis GO:0006909 60 38 0,000 0,24553149 0,26217382 ! maintenance of location in cell GO:0051651 69 38 0,000 0,24553149 0,26205217 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,25111085 0,26788263 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,25111085 0,26775844 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,25111085 0,26763436 ! chromatin remodeling GO:0006338 68 39 0,000 0,25111085 0,2675104 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,25111085 0,26738655 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,25664927 0,27315749 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,25664927 0,27303114 ! peptide metabolic process GO:0006518 56 40 0,000 0,25664927 0,27290491 ! inner ear development GO:0048839 57 40 0,000 0,25664927 0,2727788 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,25664927 0,27265281 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,25664927 0,27252693 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,25664927 0,27240117 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,25664927 0,27227552 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,26214705 0,27797981 ! striated muscle contraction GO:0006941 62 41 0,000 0,26214705 0,27785171 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,26214705 0,27772373 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,26214705 0,27759586 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,26760448 0,2832445 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,26760448 0,28311422 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,26760448 0,28298405 ! excretion GO:0007588 63 42 0,000 0,26760448 0,282854 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,26760448 0,28272407 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,26760448 0,28259426 ! regulation of cell shape GO:0008360 78 42 0,000 0,26760448 0,28246457 ! neuromuscular process GO:0050905 79 43 0,000 0,27302186 0,28805058 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,27302186 0,28791851 ! tRNA processing GO:0008033 49 43 0,000 0,27302186 0,28778656 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,27302186 0,28765473 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,27839947 0,29318625 ! regulation of ion transport GO:0043269 57 44 0,000 0,27839947 0,29305207 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,27839947 0,29291801 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,27839947 0,29278408 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,27839947 0,29265026 ! RNA catabolic process GO:0006401 64 45 0,000 0,28373761 0,2981254 ! regulation of translational initiation GO:0006446 64 45 0,000 0,28373761 0,29798927 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,28373761 0,29785326 ! cell recognition GO:0008037 58 45 0,000 0,28373761 0,29771738 ! cell redox homeostasis GO:0045454 63 46 0,000 0,28903656 0,30313912 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,28903656 0,30300095 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,28903656 0,30286291 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,29429661 0,30823416 ! viral infectious cycle GO:0019058 71 47 0,000 0,29429661 0,30809386 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,29429661 0,30795369 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,29429661 0,30781365 ! chloride transport GO:0006821 67 48 0,000 0,29951805 0,31313251 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,29951805 0,31299024 ! gastrulation GO:0007369 73 48 0,000 0,29951805 0,3128481 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,29951805 0,31270609 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,29951805 0,31256421 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,29951805 0,31242246 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,30470115 0,31768479 ! sensory perception of smell GO:0007608 61 49 0,000 0,30470115 0,31754084 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,30470115 0,31739703 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,30470115 0,31725335 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,30470115 0,31710979 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,30470115 0,31696637 ! regulation of actin filament length GO:0030832 72 50 0,000 0,30984619 0,32217281 ! proton transport GO:0015992 75 50 0,000 0,30984619 0,32202722 ! positive regulation of secretion GO:0051047 71 51 0,000 0,31495346 0,32718742 ! hydrogen transport GO:0006818 77 51 0,000 0,31495346 0,32703971 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,31495346 0,32689213 ! adult behavior GO:0030534 80 51 0,000 0,31495346 0,32674468 ! transition metal ion transport GO:0000041 74 52 0,000 0,32002322 0,33185456 ! regulation of cellular component size GO:0032535 74 52 0,000 0,32002322 0,331705 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,32002322 0,33155559 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,32505575 0,33661784 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,32505575 0,33646635 ! amino acid transport GO:0006865 84 54 0,000 0,33005132 0,3414836 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,33005132 0,34133005 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,33005132 0,34117665 ! exocytosis GO:0006887 74 55 0,000 0,3350102 0,34614711 ! mesoderm development GO:0007498 76 55 0,000 0,3350102 0,34599168 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,3350102 0,34583638 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,3350102 0,34568123 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,33993266 0,35060319 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,33993266 0,35044604 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,34481896 0,3553242 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,34481896 0,35516507 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,34966937 0,3599998 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,35448415 0,36479353 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,35926355 0,36954658 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,36400784 0,37425929 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,36400784 0,37409206 ! amine catabolic process GO:0009310 90 62 0,000 0,36871727 0,37876271 ! neurotransmitter transport GO:0006836 81 62 0,000 0,36871727 0,37859362 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,36871727 0,37842468 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,36871727 0,37825589 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,37803257 0,38763928 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,37803257 0,38746654 ! adaptive immune response GO:0002250 94 64 0,000 0,37803257 0,38729395 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! defense response to bacterium GO:0042742 73 65 0,000 0,38263894 0,39183863 ! activation of immune response GO:0002253 83 65 0,000 0,38263894 0,39166425 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,38721146 0,39616831 ! regulation of immune effector process GO:0002697 101 66 0,000 0,38721146 0,39599216 ! acute inflammatory response GO:0002526 92 68 0,000 0,39625593 0,40506161 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,39625593 0,40488167 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,39625593 0,40470188 ! inorganic anion transport GO:0015698 93 68 0,000 0,39625593 0,40452225 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,40072836 0,40890649 ! amine transport GO:0015837 101 70 0,000 0,40516792 0,41325331 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,40957484 0,41756301 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,40957484 0,417378 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,41394937 0,42164905 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,41829173 0,42588357 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,42260217 0,43008185 ! digestion GO:0007586 97 74 0,000 0,42260217 0,42989163 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,42688091 0,4340522 ! tRNA metabolic process GO:0006399 95 76 0,000 0,43112818 0,43817712 ! response to unfolded protein GO:0006986 99 76 0,000 0,43112818 0,43798358 ! protein ubiquitination GO:0016567 125 77 0,000 0,43534423 0,4420714 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,43534423 0,44187631 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,43534423 0,4416814 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,43952927 0,44573074 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,44368353 0,44974531 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,44368353 0,44954719 ! chromatin assembly GO:0031497 102 80 0,000 0,44780723 0,4535256 GO:0006334|nucleosome assembly, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,44780723 0,45332598 ! mRNA transport GO:0051028 121 81 0,000 0,4519006 0,45726854 ! regulation of neurological system process GO:0031644 122 81 0,000 0,4519006 0,45706745 ! vitamin metabolic process GO:0006766 103 81 0,000 0,4519006 0,45686654 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,46400094 0,46889374 ! nucleosome organization GO:0034728 114 87 0,000 0,47583616 0,48064258 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,47583616 0,48043159 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,47583616 0,48022078 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,47972331 0,48393141 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,47972331 0,48371926 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,47972331 0,48350728 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,48358187 0,48718279 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,48741203 0,49082647 ! RNA localization GO:0006403 135 91 0,000 0,491214 0,4944386 ! ATP metabolic process GO:0046034 137 91 0,000 0,491214 0,49422231 ! DNA recombination GO:0006310 146 92 0,000 0,49498798 0,49780164 ! sulfur metabolic process GO:0006790 118 92 0,000 0,49498798 0,49758407 ! electron transport chain GO:0022900 123 94 0,000 0,50245282 0,50486741 ! carboxylic acid transport GO:0046942 147 95 0,000 0,50614408 0,50835432 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,50980816 0,5118109 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,50980816 0,5115876 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,50980816 0,51136449 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,50980816 0,51114158 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,51344527 0,51456389 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,51344527 0,51433977 ! calcium ion transport GO:0006816 167 99 0,000 0,52063934 0,52131933 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,5241967 0,52465292 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,5241967 0,52442471 ! divalent metal ion transport GO:0070838 171 100 0,000 0,5241967 0,5241967