pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6608-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! urogenital system development GO:0001655 137 69 7,000 6,541E-09 1,574E-05 ! negative regulation of translation GO:0017148 29 20 4,000 8,782E-08 1,056E-04 ! positive regulation of inflammatory response GO:0050729 35 21 4,000 1,147E-07 9,201E-05 ! branching morphogenesis of a tube GO:0048754 97 45 5,000 2,305E-07 1,386E-04 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 2,363E-07 1,137E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 2,638E-07 1,058E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 3,623E-07 1,245E-04 GO:0045936|negative regulation of phosphate metabolic process, ! morphogenesis of a branching structure GO:0001763 111 52 5,000 5,571E-07 1,675E-04 ! cartilage development GO:0051216 90 52 5,000 5,571E-07 1,489E-04 ! gland development GO:0048732 206 88 6,000 8,152E-07 1,961E-04 ! regulation of cell cycle process GO:0010564 149 90 6,000 9,501E-07 2,078E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 3,000 1,03E-06 2,065E-04 GO:0060675|ureteric bud morphogenesis, ! metanephros development GO:0001656 74 32 4,000 1,078E-06 1,996E-04 ! kidney development GO:0001822 122 60 5,000 1,319E-06 2,266E-04 ! forebrain development GO:0030900 188 95 6,000 1,372E-06 2,2E-04 ! stem cell division GO:0017145 11 5 2,000 1,879E-06 2,826E-04 GO:0048103|somatic stem cell division, ! mitotic sister chromatid segregation GO:0000070 57 36 4,000 1,981E-06 2,804E-04 ! sister chromatid segregation GO:0000819 58 37 4,000 2,28E-06 3,048E-04 ! neutrophil chemotaxis GO:0030593 27 17 3,000 2,415E-06 3,059E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 5,000 2,542E-06 3,058E-04 ! negative regulation of kinase activity GO:0033673 131 68 5,000 2,775E-06 3,179E-04 ! negative regulation of transferase activity GO:0051348 140 72 5,000 3,886E-06 4,25E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 4,851E-06 5,075E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 4,897E-06 4,909E-04 ! phosphoinositide-mediated signaling GO:0048015 131 75 5,000 4,937E-06 4,752E-04 ! collagen fibril organization GO:0030199 59 21 3,000 5,966E-06 5,52E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 6,157E-06 5,487E-04 ! prostate gland development GO:0030850 13 7 2,000 6,522E-06 5,604E-04 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 2,000 6,522E-06 5,411E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 6,522E-06 5,231E-04 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 5,000 6,687E-06 5,19E-04 ! pigmentation GO:0043473 100 46 4,000 6,876E-06 5,17E-04 ! central nervous system neuron development GO:0021954 46 22 3,000 7,258E-06 5,292E-04 ! ureteric bud development GO:0001657 43 22 3,000 7,258E-06 5,136E-04 ! positive regulation of defense response GO:0031349 76 47 4,000 7,658E-06 5,265E-04 ! positive regulation of cell cycle GO:0045787 89 48 4,000 8,509E-06 5,687E-04 ! regulation of inflammatory response GO:0050727 75 48 4,000 8,509E-06 5,533E-04 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 2,000 1,039E-05 6,579E-04 ! regulation of pigmentation during development GO:0048070 24 8 2,000 1,039E-05 6,41E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,039E-05 6,25E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,039E-05 6,098E-04 ! dendrite morphogenesis GO:0048813 13 8 2,000 1,039E-05 5,953E-04 ! regulation of ossification GO:0030278 117 50 4,000 1,043E-05 5,837E-04 ! negative regulation of immune system process GO:0002683 95 50 4,000 1,043E-05 5,704E-04 ! central nervous system neuron differentiation GO:0021953 50 24 3,000 1,045E-05 5,587E-04 ! tube morphogenesis GO:0035239 176 86 5,000 1,094E-05 5,722E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,457E-05 7,458E-04 ! axon extension GO:0048675 15 9 2,000 1,552E-05 7,779E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,552E-05 7,621E-04 ! aging GO:0007568 103 55 4,000 1,673E-05 8,052E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 1,937E-05 9,139E-04 ! dendrite development GO:0016358 59 28 3,000 1,977E-05 9,149E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,995E-05 9,058E-04 ! regulation of bone remodeling GO:0046850 137 57 4,000 1,995E-05 8,89E-04 ! positive regulation of cell migration GO:0030335 126 57 4,000 1,995E-05 8,728E-04 ! regulation of tissue remodeling GO:0034103 140 58 4,000 2,173E-05 9,337E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,208E-05 9,319E-04 ! SMAD protein nuclear translocation GO:0007184 20 10 2,000 2,208E-05 9,158E-04 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 2,208E-05 9,003E-04 ! central nervous system neuron axonogenesis GO:0021955 22 10 2,000 2,208E-05 8,853E-04 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,208E-05 8,708E-04 ! negative regulation of BMP signaling pathway GO:0030514 19 10 2,000 2,208E-05 8,567E-04 ! interphase GO:0051325 213 98 5,000 2,313E-05 8,834E-04 ! cell cycle arrest GO:0007050 213 100 5,000 2,595E-05 9,754E-04 ! cell junction assembly GO:0034329 78 30 3,000 2,623E-05 9,709E-04 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 2,783E-05 1,014E-03 ! detection of mechanical stimulus GO:0050982 22 11 2,000 3,023E-05 1,085E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 3,023E-05 1,07E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 3,023E-05 1,054E-03 GO:0010829|negative regulation of glucose transport, ! regulation of mitosis GO:0007088 105 63 4,000 3,257E-05 1,119E-03 GO:0051783|regulation of nuclear division, ! spindle organization GO:0007051 46 32 3,000 3,411E-05 1,156E-03 ! positive regulation of cell motion GO:0051272 146 64 4,000 3,517E-05 1,175E-03 ! leukocyte chemotaxis GO:0030595 50 33 3,000 3,864E-05 1,273E-03 GO:0060326|cell chemotaxis, ! regulation of B cell proliferation GO:0030888 20 12 2,000 4,013E-05 1,305E-03 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 4,013E-05 1,287E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 35 12 2,000 4,013E-05 1,27E-03 ! gland morphogenesis GO:0022612 29 12 2,000 4,013E-05 1,254E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 4,013E-05 1,238E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cell growth GO:0030308 132 67 4,000 4,393E-05 1,338E-03 ! chromosome segregation GO:0007059 113 67 4,000 4,393E-05 1,321E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 5,064E-05 1,504E-03 ! appendage morphogenesis GO:0035107 135 70 4,000 5,428E-05 1,593E-03 GO:0035108|limb morphogenesis, ! cell junction organization GO:0034330 86 36 3,000 5,487E-05 1,591E-03 ! positive regulation of cell development GO:0010720 80 36 3,000 5,487E-05 1,572E-03 ! reproductive structure development GO:0048608 113 71 4,000 5,813E-05 1,645E-03 ! appendage development GO:0048736 136 71 4,000 5,813E-05 1,626E-03 GO:0060173|limb development, ! regulation of protein stability GO:0031647 73 37 3,000 6,125E-05 1,694E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 6,125E-05 1,675E-03 ! hair follicle morphogenesis GO:0031069 26 14 2,000 6,584E-05 1,78E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 6,584E-05 1,76E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 6,584E-05 1,741E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 6,815E-05 1,782E-03 GO:0042593|glucose homeostasis, ! regulation of the force of heart contraction GO:0002026 26 15 2,000 8,195E-05 2,12E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 8,195E-05 2,097E-03 ! multicellular organismal metabolic process GO:0044236 57 40 3,000 8,362E-05 2,118E-03 ! mesenchymal cell development GO:0014031 87 40 3,000 8,362E-05 2,096E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of T cell differentiation GO:0045580 70 41 3,000 9,224E-05 2,288E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,004E-04 2,466E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! neuron migration GO:0001764 79 42 3,000 1,015E-04 2,467E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,114E-04 2,68E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,157E-04 2,757E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 1,214E-04 2,864E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,214E-04 2,837E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,214E-04 2,809E-03 ! negative regulation of growth GO:0045926 155 84 4,000 1,297E-04 2,973E-03 ! glycolysis GO:0006096 65 45 3,000 1,333E-04 3,025E-03 ! leukocyte migration GO:0050900 68 45 3,000 1,333E-04 2,997E-03 ! epidermis morphogenesis GO:0048730 40 18 2,000 1,451E-04 3,233E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,451E-04 3,203E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,451E-04 3,174E-03 ! regulation of BMP signaling pathway GO:0030510 32 18 2,000 1,451E-04 3,145E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 2,000 1,451E-04 3,117E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 1,453E-04 3,094E-03 ! regulation of cell adhesion GO:0030155 212 89 4,000 1,704E-04 3,597E-03 ! pigmentation during development GO:0048066 41 19 2,000 1,716E-04 3,59E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 1,717E-04 3,562E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,717E-04 3,532E-03 ! regulation of action potential GO:0001508 95 49 3,000 1,862E-04 3,796E-03 ! regulation of defense response GO:0031347 149 92 4,000 1,991E-04 4,026E-03 ! positive regulation of ossification GO:0045778 47 20 2,000 2,01E-04 4,03E-03 ! response to alkaloid GO:0043279 38 20 2,000 2,01E-04 3,997E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,01E-04 3,964E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,01E-04 3,932E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,01E-04 3,9E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,01E-04 3,869E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 2,095E-04 4E-03 ! regulation of membrane potential GO:0042391 164 93 4,000 2,095E-04 3,968E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,176E-04 4,09E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 3,000 2,176E-04 4,059E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,335E-04 4,322E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,335E-04 4,289E-03 ! cell aging GO:0007569 44 21 2,000 2,335E-04 4,256E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 2,335E-04 4,224E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen catabolic process GO:0030574 28 21 2,000 2,335E-04 4,193E-03 ! positive regulation of growth GO:0045927 90 52 3,000 2,347E-04 4,183E-03 ! response to UV GO:0009411 104 53 3,000 2,527E-04 4,471E-03 ! positive regulation of bone remodeling GO:0046852 51 22 2,000 2,692E-04 4,728E-03 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 2,000 2,692E-04 4,694E-03 ! glutamate signaling pathway GO:0007215 41 22 2,000 2,692E-04 4,66E-03 ! keratinization GO:0031424 28 22 2,000 2,692E-04 4,627E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,692E-04 4,594E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,692E-04 4,562E-03 ! renal system process GO:0003014 41 22 2,000 2,692E-04 4,53E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 2,692E-04 4,498E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 2,692E-04 4,467E-03 ! activation of phospholipase C activity GO:0007202 103 54 3,000 2,717E-04 4,478E-03 GO:0010863|positive regulation of phospholipase C activity, ! glucose catabolic process GO:0006007 82 55 3,000 2,917E-04 4,774E-03 ! positive regulation of phospholipase activity GO:0010518 104 55 3,000 2,917E-04 4,742E-03 ! heart morphogenesis GO:0003007 97 55 3,000 2,917E-04 4,71E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 3,083E-04 4,945E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 3,083E-04 4,912E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 3,083E-04 4,88E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 3,083E-04 4,848E-03 ! sex determination GO:0007530 47 23 2,000 3,083E-04 4,817E-03 ! platelet activation GO:0030168 37 23 2,000 3,083E-04 4,786E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,281E-04 5,06E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 3,281E-04 5,028E-03 ! protein maturation by protein folding GO:0022417 13 5 1,000 3,281E-04 4,996E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,281E-04 4,965E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,281E-04 4,934E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,281E-04 4,903E-03 ! microvillus organization GO:0032528 7 5 1,000 3,281E-04 4,873E-03 GO:0030033|microvillus assembly, ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 3,281E-04 4,843E-03 ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 1,000 3,281E-04 4,814E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,281E-04 4,784E-03 ! forebrain neuron development GO:0021884 13 5 1,000 3,281E-04 4,756E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,281E-04 4,727E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 3,281E-04 4,699E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,281E-04 4,671E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 3,281E-04 4,644E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,281E-04 4,617E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 3,281E-04 4,59E-03 GO:0042634|regulation of hair cycle, ! glial cell migration GO:0008347 11 5 1,000 3,281E-04 4,563E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 3,281E-04 4,537E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 3,281E-04 4,511E-03 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 1,000 3,281E-04 4,485E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 3,281E-04 4,46E-03 ! regulation of phospholipase activity GO:0010517 106 57 3,000 3,348E-04 4,526E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 3,508E-04 4,716E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,508E-04 4,69E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 3,508E-04 4,664E-03 ! regulation of behavior GO:0050795 43 24 2,000 3,508E-04 4,638E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 3,508E-04 4,613E-03 ! positive regulation of lipase activity GO:0060193 108 58 3,000 3,58E-04 4,682E-03 ! skeletal system morphogenesis GO:0048705 105 59 3,000 3,823E-04 4,973E-03 ! DNA catabolic process GO:0006308 86 59 3,000 3,823E-04 4,946E-03 ! myelination GO:0042552 45 25 2,000 3,97E-04 5,108E-03 ! vasculogenesis GO:0001570 46 25 2,000 3,97E-04 5,081E-03 ! regulation of heart contraction GO:0008016 110 60 3,000 4,078E-04 5,192E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 4,078E-04 5,164E-03 ! negative regulation of response to stimulus GO:0048585 100 60 3,000 4,078E-04 5,137E-03 ! molting cycle process GO:0022404 50 26 2,000 4,469E-04 5,6E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 4,469E-04 5,571E-03 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 4,469E-04 5,542E-03 ! regulation of homeostatic process GO:0032844 134 62 3,000 4,624E-04 5,705E-03 ! myoblast cell fate commitment GO:0048625 16 6 1,000 4,903E-04 6,019E-03 ! neuron remodeling GO:0016322 15 6 1,000 4,903E-04 5,988E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 4,903E-04 5,958E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 4,903E-04 5,928E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! male sex determination GO:0030238 15 6 1,000 4,903E-04 5,898E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 4,903E-04 5,869E-03 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 14 6 1,000 4,903E-04 5,84E-03 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 1,000 4,903E-04 5,811E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 4,903E-04 5,783E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 4,903E-04 5,754E-03 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 1,000 4,903E-04 5,726E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,903E-04 5,699E-03 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 1,000 4,903E-04 5,671E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,903E-04 5,644E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 5,006E-04 5,736E-03 ! multicellular organismal catabolic process GO:0044243 36 27 2,000 5,006E-04 5,708E-03 ! male gonad development GO:0008584 44 27 2,000 5,006E-04 5,682E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 5,006E-04 5,655E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 5,006E-04 5,628E-03 ! embryonic limb morphogenesis GO:0030326 125 65 3,000 5,537E-04 6,196E-03 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of protein modification process GO:0031400 60 28 2,000 5,583E-04 6,219E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 5,583E-04 6,19E-03 ! extracellular matrix organization GO:0030198 133 66 3,000 5,868E-04 6,476E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 6,201E-04 6,813E-03 ! hexose catabolic process GO:0019320 104 67 3,000 6,212E-04 6,794E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 6,212E-04 6,763E-03 ! regulation of lipase activity GO:0060191 130 68 3,000 6,571E-04 7,122E-03 ! forebrain neuron differentiation GO:0021879 16 7 1,000 6,838E-04 7,378E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,838E-04 7,345E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,838E-04 7,312E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 6,838E-04 7,28E-03 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 6,838E-04 7,248E-03 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 6,838E-04 7,216E-03 GO:0031958|corticosteroid receptor signaling pathway, ! organ growth GO:0035265 15 7 1,000 6,838E-04 7,184E-03 ! spindle checkpoint GO:0031577 15 7 1,000 6,838E-04 7,153E-03 ! regulation of meiosis GO:0040020 12 7 1,000 6,838E-04 7,122E-03 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 16 7 1,000 6,838E-04 7,091E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 6,838E-04 7,061E-03 ! negative regulation of nuclear division GO:0051784 14 7 1,000 6,838E-04 7,031E-03 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 1,000 6,838E-04 7,001E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 6,838E-04 6,971E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 6,838E-04 6,942E-03 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 1,000 6,838E-04 6,913E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 6,861E-04 6,907E-03 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 6,861E-04 6,878E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 6,861E-04 6,85E-03 ! cell cycle checkpoint GO:0000075 137 69 3,000 6,944E-04 6,904E-03 ! collagen metabolic process GO:0032963 45 31 2,000 7,564E-04 7,489E-03 ! response to mechanical stimulus GO:0009612 57 32 2,000 8,311E-04 8,195E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 8,311E-04 8,162E-03 ! BMP signaling pathway GO:0030509 64 32 2,000 8,311E-04 8,129E-03 ! hindbrain development GO:0030902 61 32 2,000 8,311E-04 8,096E-03 ! eye development GO:0001654 143 74 3,000 9,038E-04 8,768E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 9,083E-04 8,776E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 9,083E-04 8,741E-03 ! generation of neurons in the forebrain GO:0021872 18 8 1,000 9,083E-04 8,706E-03 ! pigment granule organization GO:0048753 16 8 1,000 9,083E-04 8,672E-03 ! ER overload response GO:0006983 12 8 1,000 9,083E-04 8,638E-03 ! melanin metabolic process GO:0006582 15 8 1,000 9,083E-04 8,604E-03 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 1,000 9,083E-04 8,57E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 9,083E-04 8,536E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 9,083E-04 8,503E-03 ! response to UV-B GO:0010224 16 8 1,000 9,083E-04 8,47E-03 ! positive regulation of epidermis development GO:0045684 13 8 1,000 9,083E-04 8,437E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 9,083E-04 8,405E-03 ! post-embryonic development GO:0009791 69 33 2,000 9,104E-04 8,392E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 2,000 9,942E-04 9,13E-03 ! monosaccharide catabolic process GO:0046365 115 76 3,000 9,988E-04 9,137E-03 ! embryonic skeletal system morphogenesis GO:0048704 59 35 2,000 1,083E-03 9,869E-03 ! calcium-mediated signaling GO:0019722 62 35 2,000 1,083E-03 9,831E-03 ! blood coagulation GO:0007596 146 78 3,000 1,101E-03 9,955E-03 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 3,000 1,101E-03 9,918E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,154E-03 0,01036112 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 1,154E-03 0,0103226 ! regulation of developmental growth GO:0048638 15 9 1,000 1,163E-03 0,01036666 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,163E-03 0,01032841 ! regulation of glycolysis GO:0006110 21 9 1,000 1,163E-03 0,01029044 ! microtubule bundle formation GO:0001578 21 9 1,000 1,163E-03 0,01025274 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,163E-03 0,01021533 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,163E-03 0,01017818 ! T cell selection GO:0045058 23 9 1,000 1,163E-03 0,0101413 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,163E-03 0,01010469 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 1,163E-03 0,01006834 ! behavioral fear response GO:0001662 22 9 1,000 1,163E-03 0,01003226 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,163E-03 9,996E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,163E-03 9,961E-03 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,163E-03 9,926E-03 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,163E-03 9,89E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,163E-03 9,856E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,176E-03 9,931E-03 ! protein import into nucleus GO:0006606 158 80 3,000 1,209E-03 0,01017445 ! T cell activation GO:0042110 168 81 3,000 1,267E-03 0,01061815 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 1,267E-03 0,01058128 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 3,000 1,267E-03 0,01054467 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,267E-03 0,01050831 ! nuclear import GO:0051170 161 81 3,000 1,267E-03 0,01047219 ! response to drug GO:0042493 143 82 3,000 1,326E-03 0,01092262 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,378E-03 0,01131651 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 1,378E-03 0,01127802 ! nucleus organization GO:0006997 67 38 2,000 1,378E-03 0,01123979 ! response to oxygen levels GO:0070482 176 83 3,000 1,387E-03 0,01127014 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,449E-03 0,01173559 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,449E-03 0,01169621 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,449E-03 0,01165709 ! positive regulation of heart contraction GO:0045823 16 10 1,000 1,449E-03 0,01161823 ! B cell proliferation GO:0042100 18 10 1,000 1,449E-03 0,01157963 ! epithelial cell development GO:0002064 20 10 1,000 1,449E-03 0,01154129 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,449E-03 0,0115032 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,449E-03 0,01146536 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 1,449E-03 0,01142777 ! salivary gland development GO:0007431 27 10 1,000 1,449E-03 0,01139042 ! midbrain development GO:0030901 13 10 1,000 1,449E-03 0,01135332 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,449E-03 0,01131646 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,449E-03 0,01127984 ! response to nicotine GO:0035094 20 10 1,000 1,449E-03 0,01124345 ! localization within membrane GO:0051668 20 10 1,000 1,449E-03 0,0112073 ! hemostasis GO:0007599 158 84 3,000 1,449E-03 0,01117677 ! regulation of ligase activity GO:0051340 142 84 3,000 1,449E-03 0,01114106 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 1,487E-03 0,01139138 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,487E-03 0,01135521 ! mitochondrion organization GO:0007005 148 86 3,000 1,581E-03 0,01203717 ! alcohol catabolic process GO:0046164 130 86 3,000 1,581E-03 0,0119992 ! protein localization in nucleus GO:0034504 176 87 3,000 1,65E-03 0,01248209 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 2,000 1,719E-03 0,01296888 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,719E-03 0,01292835 ! T cell differentiation GO:0030217 81 41 2,000 1,719E-03 0,01288808 ! keratinocyte differentiation GO:0030216 62 41 2,000 1,719E-03 0,01284805 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 1,764E-03 0,01313888 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,764E-03 0,01309832 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,764E-03 0,01305802 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,764E-03 0,01301797 ! adult heart development GO:0007512 14 11 1,000 1,764E-03 0,01297815 ! negative regulation of ossification GO:0030279 26 11 1,000 1,764E-03 0,01293859 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 1,764E-03 0,01289926 ! DNA methylation GO:0006306 19 11 1,000 1,764E-03 0,01286017 GO:0006305|DNA alkylation, ! oocyte differentiation GO:0009994 18 11 1,000 1,764E-03 0,01282132 ! thymus development GO:0048538 27 11 1,000 1,764E-03 0,0127827 ! cardiac cell differentiation GO:0035051 31 11 1,000 1,764E-03 0,01274431 ! sequestering of metal ion GO:0051238 14 11 1,000 1,764E-03 0,01270616 ! regulation of embryonic development GO:0045995 27 11 1,000 1,764E-03 0,01266823 ! response to reactive oxygen species GO:0000302 67 42 2,000 1,844E-03 0,01320394 ! sex differentiation GO:0007548 145 90 3,000 1,869E-03 0,01334105 ! epithelial cell differentiation GO:0030855 79 43 2,000 1,974E-03 0,01405078 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 2,000 1,974E-03 0,01400933 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,109E-03 0,01492152 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 2,109E-03 0,01487776 ! virus-host interaction GO:0019048 29 12 1,000 2,109E-03 0,01483426 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,109E-03 0,01479101 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 2,109E-03 0,01474801 ! positive regulation of cell growth GO:0030307 22 12 1,000 2,109E-03 0,01470527 ! fear response GO:0042596 26 12 1,000 2,109E-03 0,01466276 ! regulation of phagocytosis GO:0050764 16 12 1,000 2,109E-03 0,01462051 ! histone acetylation GO:0016573 26 12 1,000 2,109E-03 0,0145785 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,109E-03 0,01453672 ! T cell homeostasis GO:0043029 25 12 1,000 2,109E-03 0,01449519 ! spleen development GO:0048536 22 12 1,000 2,109E-03 0,01445389 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,109E-03 0,01441283 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 2,109E-03 0,0143773 ! male sex differentiation GO:0046661 76 44 2,000 2,109E-03 0,01433668 ! regulation of T cell activation GO:0050863 158 94 3,000 2,191E-03 0,01484743 ! detection of stimulus involved in sensory perception GO:0050906 66 45 2,000 2,251E-03 0,01521009 ! cell growth GO:0016049 84 45 2,000 2,251E-03 0,01516749 ! regulation of Rho protein signal transduction GO:0035023 213 95 3,000 2,277E-03 0,01530182 ! leukocyte differentiation GO:0002521 202 96 3,000 2,365E-03 0,01585185 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,397E-03 0,0160227 ! negative regulation of cell migration GO:0030336 115 46 2,000 2,397E-03 0,01597832 ! epidermal cell differentiation GO:0009913 68 46 2,000 2,397E-03 0,01593418 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,456E-03 0,01627878 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,483E-03 0,01640937 ! Golgi organization GO:0007030 24 13 1,000 2,483E-03 0,01636442 ! cell-cell junction assembly GO:0007043 27 13 1,000 2,483E-03 0,0163197 ! exocrine system development GO:0035272 32 13 1,000 2,483E-03 0,01627524 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,483E-03 0,01623101 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,483E-03 0,01618702 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,483E-03 0,01614328 ! regulation of epidermis development GO:0045682 19 13 1,000 2,483E-03 0,01609976 ! insulin secretion GO:0030073 23 13 1,000 2,483E-03 0,01605648 ! endosome transport GO:0016197 108 47 2,000 2,55E-03 0,01644911 ! skeletal muscle tissue development GO:0007519 186 99 3,000 2,645E-03 0,01701367 GO:0060538|skeletal muscle organ development, ! cellular component disassembly GO:0022411 86 48 2,000 2,709E-03 0,01737868 ! activation of caspase activity GO:0006919 84 48 2,000 2,709E-03 0,01733246 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,873E-03 0,01833638 ! detection of abiotic stimulus GO:0009582 74 49 2,000 2,873E-03 0,01828787 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,885E-03 0,01831692 ! palate development GO:0060021 31 14 1,000 2,885E-03 0,01826872 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,885E-03 0,01822077 ! response to gamma radiation GO:0010332 28 14 1,000 2,885E-03 0,01817307 ! positive regulation of bone mineralization GO:0030501 29 14 1,000 2,885E-03 0,01812562 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 2,885E-03 0,01807842 ! embryonic skeletal system development GO:0048706 85 51 2,000 3,22E-03 0,02012492 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 3,317E-03 0,02067305 ! positive regulation of cell size GO:0045793 27 15 1,000 3,317E-03 0,02061963 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,317E-03 0,02056649 ! pituitary gland development GO:0021983 29 15 1,000 3,317E-03 0,02051362 ! positive regulation of biomineral formation GO:0070169 30 15 1,000 3,317E-03 0,02046102 ! regulation of vasodilation GO:0042312 26 15 1,000 3,317E-03 0,02040869 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,317E-03 0,02035663 ! dopamine metabolic process GO:0042417 35 15 1,000 3,317E-03 0,02030483 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,317E-03 0,02025329 ! regulation of muscle contraction GO:0006937 81 52 2,000 3,403E-03 0,02072885 ! cell maturation GO:0048469 100 53 2,000 3,592E-03 0,02182497 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 3,592E-03 0,02176999 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,776E-03 0,02282726 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 3,776E-03 0,02277005 GO:0031114|regulation of microtubule depolymerization, ! regulation of dephosphorylation GO:0035303 43 16 1,000 3,776E-03 0,02271312 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 3,776E-03 0,02265648 ! negative regulation of immune response GO:0050777 35 16 1,000 3,776E-03 0,02260012 ! embryonic digit morphogenesis GO:0042733 34 16 1,000 3,776E-03 0,02254404 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,776E-03 0,02248824 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,776E-03 0,02243272 ! defense response to virus GO:0051607 37 16 1,000 3,776E-03 0,02237746 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,989E-03 0,02358198 GO:0010952|positive regulation of peptidase activity, ! negative regulation of cell motion GO:0051271 134 55 2,000 3,989E-03 0,02352418 ! skeletal muscle fiber development GO:0048741 111 56 2,000 4,197E-03 0,02469083 ! regulation of DNA replication GO:0006275 101 56 2,000 4,197E-03 0,02463061 ! myoblast differentiation GO:0045445 45 17 1,000 4,263E-03 0,02495781 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,263E-03 0,02489723 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,263E-03 0,02483695 ! metencephalon development GO:0022037 30 17 1,000 4,263E-03 0,02477696 ! regulation of viral genome replication GO:0045069 28 17 1,000 4,263E-03 0,02471725 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,263E-03 0,02465784 ! regulation of protein binding GO:0043393 33 17 1,000 4,263E-03 0,02459871 ! muscle fiber development GO:0048747 112 57 2,000 4,412E-03 0,02539432 ! neuron maturation GO:0042551 42 18 1,000 4,778E-03 0,0274373 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,778E-03 0,02737197 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 4,778E-03 0,02730696 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 4,778E-03 0,02724225 GO:0050886|endocrine process, ! patterning of blood vessels GO:0001569 39 18 1,000 4,778E-03 0,02717785 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 4,778E-03 0,02711375 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 4,778E-03 0,02704995 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,778E-03 0,02698645 ! lipid phosphorylation GO:0046834 35 19 1,000 5,32E-03 0,02997696 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,32E-03 0,02990692 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,32E-03 0,0298372 ! actin filament bundle formation GO:0051017 42 19 1,000 5,32E-03 0,02976782 ! neuromuscular junction development GO:0007528 34 19 1,000 5,32E-03 0,02969875 ! plasma membrane fusion GO:0045026 28 19 1,000 5,32E-03 0,02963 ! protein export from nucleus GO:0006611 36 19 1,000 5,32E-03 0,02956157 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 5,32E-03 0,02949346 ! cellular pigmentation GO:0033059 36 19 1,000 5,32E-03 0,02942566 ! cell-cell junction organization GO:0045216 35 19 1,000 5,32E-03 0,02935817 ! proximal/distal pattern formation GO:0009954 32 19 1,000 5,32E-03 0,02929099 ! peptide hormone secretion GO:0030072 31 19 1,000 5,32E-03 0,02922411 ! ear development GO:0043583 103 62 2,000 5,584E-03 0,03060319 ! gonad development GO:0008406 98 62 2,000 5,584E-03 0,03053364 ! detection of external stimulus GO:0009581 91 63 2,000 5,838E-03 0,03185354 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 5,838E-03 0,03178148 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,889E-03 0,03198345 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,889E-03 0,03191141 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,889E-03 0,0318397 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 5,889E-03 0,03176831 ! peptide secretion GO:0002790 35 20 1,000 5,889E-03 0,03169724 ! diencephalon development GO:0021536 34 20 1,000 5,889E-03 0,03162649 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 6,1E-03 0,0326871 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 6,368E-03 0,03404935 ! germ cell development GO:0007281 118 65 2,000 6,368E-03 0,03397385 ! hormone secretion GO:0046879 38 21 1,000 6,484E-03 0,03451542 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 6,484E-03 0,03443922 ! hindlimb morphogenesis GO:0035137 43 21 1,000 6,484E-03 0,03436337 ! ovarian follicle development GO:0001541 35 21 1,000 6,484E-03 0,03428784 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 6,484E-03 0,03421265 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 6,484E-03 0,03413779 ! regulation of vasoconstriction GO:0019229 39 21 1,000 6,484E-03 0,03406325 ! oogenesis GO:0048477 36 21 1,000 6,484E-03 0,03398904 ! DNA modification GO:0006304 34 21 1,000 6,484E-03 0,03391515 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 6,484E-03 0,03384158 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 6,484E-03 0,03376833 ! response to cytokine stimulus GO:0034097 63 21 1,000 6,484E-03 0,0336954 ! gut development GO:0048565 39 21 1,000 6,484E-03 0,03362278 ! actin filament organization GO:0007015 148 66 2,000 6,644E-03 0,0343755 ! developmental maturation GO:0021700 116 66 2,000 6,644E-03 0,03430174 ! lung development GO:0030324 144 67 2,000 6,926E-03 0,03568271 ! regeneration GO:0031099 41 22 1,000 7,106E-03 0,03653053 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 7,106E-03 0,03645264 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,106E-03 0,03637508 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,106E-03 0,03629785 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 7,106E-03 0,03622095 ! protein stabilization GO:0050821 39 22 1,000 7,106E-03 0,03614437 ! negative regulation of ligase activity GO:0051352 112 68 2,000 7,215E-03 0,03662438 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 7,215E-03 0,03654727 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 7,215E-03 0,03647049 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 7,753E-03 0,03910663 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 7,753E-03 0,03902482 ! response to ethanol GO:0045471 46 23 1,000 7,753E-03 0,03894334 ! regulation of viral reproduction GO:0050792 38 23 1,000 7,753E-03 0,03886221 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 7,753E-03 0,03878142 ! regulation of bone mineralization GO:0030500 49 23 1,000 7,753E-03 0,03870096 ! hormone transport GO:0009914 40 23 1,000 7,753E-03 0,03862083 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 7,753E-03 0,03854104 GO:0006099|tricarboxylic acid cycle, ! respiratory tube development GO:0030323 150 70 2,000 7,815E-03 0,0387698 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,426E-03 0,04171384 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,426E-03 0,04162819 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 8,426E-03 0,04154288 ! multicellular organismal response to stress GO:0033555 49 24 1,000 8,426E-03 0,04145793 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 8,426E-03 0,04137332 ! lymphocyte proliferation GO:0046651 48 24 1,000 8,426E-03 0,04128906 ! leukocyte homeostasis GO:0001776 44 24 1,000 8,426E-03 0,04120514 ! protein tetramerization GO:0051262 52 24 1,000 8,426E-03 0,04112156 ! regulation of caspase activity GO:0043281 122 72 2,000 8,444E-03 0,04112459 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 8,444E-03 0,04104151 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 8,444E-03 0,04095876 ! respiratory system development GO:0060541 153 72 2,000 8,444E-03 0,04087635 ! regulation of transcription factor activity GO:0051090 126 74 2,000 9,101E-03 0,04397033 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 2,000 9,101E-03 0,04388222 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 9,101E-03 0,04379445 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 9,124E-03 0,04381783 ! response to starvation GO:0042594 42 25 1,000 9,124E-03 0,04373054 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 9,124E-03 0,0436436 ! coenzyme catabolic process GO:0009109 39 25 1,000 9,124E-03 0,04355701 ! interaction with host GO:0051701 62 25 1,000 9,124E-03 0,04347075 ! regulation of biomineral formation GO:0070167 51 25 1,000 9,124E-03 0,04338484 ! somitogenesis GO:0001756 43 25 1,000 9,124E-03 0,04329927 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,124E-03 0,04321404 ! liver development GO:0001889 53 25 1,000 9,124E-03 0,04312914 ! cell-matrix adhesion GO:0007160 163 75 2,000 9,441E-03 0,0445379 ! meiotic cell cycle GO:0051321 122 75 2,000 9,441E-03 0,04445074 ! lymphocyte differentiation GO:0030098 167 75 2,000 9,441E-03 0,04436392 ! development of primary sexual characteristics GO:0045137 124 76 2,000 9,788E-03 0,04590455 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 9,847E-03 0,04609441 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 9,847E-03 0,0460049 ! cellular response to oxidative stress GO:0034599 39 26 1,000 9,847E-03 0,04591575 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 9,847E-03 0,04582693 ! positive regulation of nuclear division GO:0051785 40 26 1,000 9,847E-03 0,04573846 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 52 26 1,000 9,847E-03 0,04565034 GO:0032943|mononuclear cell proliferation, ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 0,01014191 0,04692582 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 0,01050356 0,04850588 ! protein oligomerization GO:0051259 139 78 2,000 0,01050356 0,04841295 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,010595 0,04874105 ! protein amino acid acylation GO:0043543 55 27 1,000 0,010595 0,04864803 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 1,000 0,010595 0,04855537 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,010595 0,04846306 ! response to toxin GO:0009636 47 27 1,000 0,010595 0,0483711 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,010595 0,04827948 ! activation of protein kinase activity GO:0032147 147 79 2,000 0,01087262 0,04945088 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01087262 0,04935757 ! response to metal ion GO:0010038 140 80 2,000 0,0112491 0,05097051 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01136705 0,05140813 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 0,01136705 0,05131168 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01136705 0,05121559 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01136705 0,05111986 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01163305 0,05221849 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01216312 0,05449622 ! catechol metabolic process GO:0009712 54 29 1,000 0,01216312 0,05439493 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01216312 0,05429401 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01216312 0,05419346 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01216312 0,05409329 ! tissue homeostasis GO:0001894 48 29 1,000 0,01216312 0,05399349 GO:0048871|multicellular organismal homeostasis, ! negative regulation of transport GO:0051051 153 84 2,000 0,01282984 0,05684823 ! phenol metabolic process GO:0018958 55 30 1,000 0,01298291 0,05742073 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01298291 0,05731537 ! cofactor catabolic process GO:0051187 51 30 1,000 0,01298291 0,0572104 ! response to heat GO:0009408 50 30 1,000 0,01298291 0,05710581 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01324383 0,05814716 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 2,000 0,01366538 0,05988869 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01382612 0,06048298 GO:0055092|sterol homeostasis, ! ovulation cycle process GO:0022602 49 31 1,000 0,01382612 0,06037321 ! peptide transport GO:0015833 55 31 1,000 0,01382612 0,06026384 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01382612 0,06015486 ! myeloid leukocyte activation GO:0002274 49 31 1,000 0,01382612 0,06004628 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01382612 0,05993809 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01453123 0,06288155 ! regulation of DNA binding GO:0051101 155 88 2,000 0,01453123 0,06276865 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01469245 0,06335132 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01469245 0,06323799 ! ovulation cycle GO:0042698 51 32 1,000 0,01469245 0,06312507 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01469245 0,06301254 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01469245 0,06290042 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01469245 0,0627887 ! ossification GO:0001503 188 90 2,000 0,01542753 0,06581319 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01558162 0,06635287 ! bone development GO:0060348 189 91 2,000 0,01588713 0,06753435 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01649333 0,06998757 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01649333 0,06986435 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01649333 0,06974157 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,01649333 0,06961921 ! placenta development GO:0001890 53 34 1,000 0,01649333 0,06949729 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01649333 0,06937579 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,01682931 0,07066546 GO:0010498|proteasomal protein catabolic process, ! transcription initiation GO:0006352 153 94 2,000 0,0173119 0,0725652 ! regulation of muscle development GO:0048634 70 35 1,000 0,0174273 0,07292188 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,0174273 0,07279528 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,0174273 0,07266911 ! odontogenesis GO:0042476 66 35 1,000 0,0174273 0,07254339 ! female gonad development GO:0008585 58 35 1,000 0,0174273 0,0724181 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,0174273 0,07229324 ! cytokine production GO:0001816 59 35 1,000 0,0174273 0,07216881 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,0174273 0,07204481 ! detection of stimulus GO:0051606 151 96 2,000 0,01830014 0,07552337 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,01838324 0,07573642 ! aerobic respiration GO:0009060 55 36 1,000 0,01838324 0,07560696 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01838324 0,07547794 ! embryonic organ development GO:0048568 57 36 1,000 0,01838324 0,07534936 ! regulation of protein localization GO:0032880 176 97 2,000 0,0188058 0,07695026 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01936087 0,07908702 ! meiosis I GO:0007127 65 37 1,000 0,01936087 0,07895297 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01936087 0,07881938 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01936087 0,07868624 ! pigment metabolic process GO:0042440 80 37 1,000 0,01936087 0,07855355 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02035991 0,08246793 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 1,000 0,02035991 0,08232932 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02035991 0,08219119 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,02035991 0,08205351 ! glucan metabolic process GO:0044042 62 38 1,000 0,02035991 0,0819163 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,02138009 0,08587728 ! ear morphogenesis GO:0042471 60 39 1,000 0,02138009 0,08573415 ! segmentation GO:0035282 67 39 1,000 0,02138009 0,0855915 ! negative regulation of binding GO:0051100 72 40 1,000 0,02242112 0,08961 ! cytokinesis GO:0000910 72 40 1,000 0,02242112 0,0894614 ! gliogenesis GO:0042063 88 41 1,000 0,02348275 0,0935422 ! hormone-mediated signaling GO:0009755 74 41 1,000 0,02348275 0,09338758 ! female gamete generation GO:0007292 61 41 1,000 0,02348275 0,09323348 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02456469 0,09736843 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02456469 0,09720828 ! regulation of tube size GO:0035150 71 42 1,000 0,02456469 0,09704866 GO:0050880|regulation of blood vessel size, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02456469 0,09688957 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02566668 0,10107042 ! glucose transport GO:0015758 65 43 1,000 0,02566668 0,10090527 ! activation of adenylate cyclase activity GO:0007190 91 44 1,000 0,02678845 0,10514358 ! hexose transport GO:0008645 67 44 1,000 0,02678845 0,10497234 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 1,000 0,02678845 0,10480165 ! B cell differentiation GO:0030183 107 44 1,000 0,02678845 0,10463152 ! developmental growth GO:0048589 82 44 1,000 0,02678845 0,10446194 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02855735 0,11117957 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02855735 0,11099996 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02855735 0,11082092 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02855735 0,11064247 ! neuron fate determination GO:0048664 7 5 0,000 0,02855735 0,11046459 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02855735 0,11028728 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02855735 0,11011053 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02855735 0,10993436 ! polyol transport GO:0015791 12 5 0,000 0,02855735 0,10975874 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02855735 0,10958369 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02855735 0,10940919 ! response to superoxide GO:0000303 10 5 0,000 0,02855735 0,10923525 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02855735 0,10906186 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02855735 0,10888902 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02855735 0,10871673 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02855735 0,10854498 ! female meiosis GO:0007143 7 5 0,000 0,02855735 0,10837377 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02855735 0,10820311 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02855735 0,10803298 ! cobalt ion transport GO:0006824 11 5 0,000 0,02855735 0,10786338 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02855735 0,10769432 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02855735 0,10752578 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02855735 0,10735777 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02855735 0,10719029 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02855735 0,10702332 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02855735 0,10685688 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02855735 0,10669095 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02855735 0,10652554 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02855735 0,10636064 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02855735 0,10619625 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02855735 0,10603237 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02855735 0,10586899 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02855735 0,10570611 ! negative chemotaxis GO:0050919 14 5 0,000 0,02855735 0,10554374 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02855735 0,10538186 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02855735 0,10522048 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02855735 0,10505959 ! behavioral response to pain GO:0048266 9 5 0,000 0,02855735 0,1048992 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02855735 0,10473929 ! Notch receptor processing GO:0007220 8 5 0,000 0,02855735 0,10457987 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02855735 0,10442093 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02855735 0,10426248 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02855735 0,1041045 ! copulation GO:0007620 9 5 0,000 0,02855735 0,10394701 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02855735 0,10378999 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02855735 0,10363344 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02855735 0,10347737 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02855735 0,10332176 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02855735 0,10316663 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02855735 0,10301195 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02855735 0,10285774 ! grooming behavior GO:0007625 6 5 0,000 0,02855735 0,102704 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02855735 0,10255071 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02855735 0,10239787 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02855735 0,1022455 ! response to protozoan GO:0001562 10 5 0,000 0,02855735 0,10209357 ! lymph vessel development GO:0001945 10 5 0,000 0,02855735 0,1019421 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02855735 0,10179107 ! endochondral ossification GO:0001958 16 5 0,000 0,02855735 0,10164049 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02855735 0,10149036 ! parathyroid gland development GO:0060017 13 5 0,000 0,02855735 0,10134067 ! anagen GO:0042640 6 5 0,000 0,02855735 0,10119142 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02855735 0,10104261 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02855735 0,10089423 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02855735 0,1007463 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02855735 0,10059879 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02855735 0,10045172 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02855735 0,10030507 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02855735 0,10015885 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02855735 0,10001306 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02855735 0,09986769 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02855735 0,09972275 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02855735 0,09957822 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02855735 0,09943411 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02855735 0,09929042 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02855735 0,09914715 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02855735 0,09900428 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02855735 0,09886183 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02855735 0,09871979 ! histidine catabolic process GO:0006548 6 5 0,000 0,02855735 0,09857815 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02855735 0,09843692 ! valine metabolic process GO:0006573 10 5 0,000 0,02855735 0,0982961 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02855735 0,09815568 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02855735 0,09801565 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02855735 0,09787603 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02855735 0,0977368 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02855735 0,09759797 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02855735 0,09745954 ! polyol catabolic process GO:0046174 7 5 0,000 0,02855735 0,09732149 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02855735 0,09718384 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02855735 0,09704657 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02855735 0,09690969 ! muscle cell migration GO:0014812 8 5 0,000 0,02855735 0,0967732 ! mitochondrial fission GO:0000266 8 5 0,000 0,02855735 0,09663709 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02855735 0,09650137 ! mRNA transcription GO:0009299 9 5 0,000 0,02855735 0,09636602 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02855735 0,09623106 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02855735 0,09609647 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02855735 0,09596225 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02855735 0,09582841 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02855735 0,09569495 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02855735 0,09556185 ! response to food GO:0032094 6 5 0,000 0,02855735 0,09542913 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02855735 0,09529677 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02855735 0,09516478 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02855735 0,09503316 GO:0032881|regulation of polysaccharide metabolic process, ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02855735 0,0949019 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02855735 0,094771 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02855735 0,09464046 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02855735 0,09451028 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02855735 0,09438046 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02855735 0,09425099 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02855735 0,09412188 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02855735 0,09399312 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02855735 0,09386472 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02855735 0,09373666 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02855735 0,09360896 ! basic amino acid transport GO:0015802 11 5 0,000 0,02855735 0,0934816 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02855735 0,09335458 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02855735 0,09322791 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02855735 0,09310159 ! depyrimidination GO:0045008 10 5 0,000 0,02855735 0,09297561 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02855735 0,09284996 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02855735 0,09272466 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02855735 0,09259969 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02855735 0,09247506 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02855735 0,09235077 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02855735 0,09222681 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02855735 0,09210318 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02855735 0,09197988 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02855735 0,09185692 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02855735 0,09173428 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02855735 0,09161196 ! response to arsenic GO:0046685 10 5 0,000 0,02855735 0,09148998 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02855735 0,09136832 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02855735 0,09124698 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02855735 0,09112596 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02855735 0,09100526 ! response to cadmium ion GO:0046686 7 5 0,000 0,02855735 0,09088489 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02855735 0,09076483 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02855735 0,09064508 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02855735 0,09052566 ! decidualization GO:0046697 11 5 0,000 0,02855735 0,09040654 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02855735 0,09028774 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02855735 0,09016926 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02855735 0,09005108 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02855735 0,08993321 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02855735 0,08981565 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02855735 0,0896984 ! neural tube patterning GO:0021532 7 5 0,000 0,02855735 0,08958145 ! embryonic cleavage GO:0040016 6 5 0,000 0,02855735 0,08946481 ! peroxisome fission GO:0016559 5 5 0,000 0,02855735 0,08934847 ! histone demethylation GO:0016577 10 5 0,000 0,02855735 0,08923243 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02855735 0,0891167 ! mitotic recombination GO:0006312 9 5 0,000 0,02855735 0,08900126 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02855735 0,08888612 ! metaphase plate congression GO:0051310 7 5 0,000 0,02855735 0,08877128 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02855735 0,08865674 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02855735 0,08854249 ! enteric nervous system development GO:0048484 8 5 0,000 0,02855735 0,08842854 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02855735 0,08831488 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02855735 0,08820151 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02855735 0,08808843 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02855735 0,08797564 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02855735 0,08786314 ! plasminogen activation GO:0031639 5 5 0,000 0,02855735 0,08775092 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02855735 0,087639 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02855735 0,08752735 ! metaphase GO:0051323 8 5 0,000 0,02855735 0,087416 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02855735 0,08730492 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02855735 0,08719413 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02855735 0,08708362 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02855735 0,08697338 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02855735 0,08686343 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02855735 0,08675375 ! response to redox state GO:0051775 5 5 0,000 0,02855735 0,08664435 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02855735 0,08653523 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02855735 0,08642638 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02855735 0,08631781 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02855735 0,0862095 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02855735 0,08610147 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02855735 0,08599371 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02855735 0,08588622 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02855735 0,08577899 ! striatum development GO:0021756 9 5 0,000 0,02855735 0,08567204 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02855735 0,08556535 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02855735 0,08545892 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02855735 0,08535276 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02855735 0,08524687 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02855735 0,08514123 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02855735 0,08503586 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02855735 0,08493075 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02855735 0,08482589 ! neuroprotection GO:0043526 6 5 0,000 0,02855735 0,0847213 ! neural plate development GO:0001840 8 5 0,000 0,02855735 0,08461696 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02855735 0,08451288 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02855735 0,08440906 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02855735 0,08430549 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02855735 0,08420217 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02855735 0,08409911 GO:0051497|negative regulation of stress fiber formation, ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02855735 0,0839963 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02855735 0,08389374 ! spindle assembly GO:0051225 6 5 0,000 0,02855735 0,08379143 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02855735 0,08368937 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02855735 0,08358756 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02855735 0,08348599 ! drug metabolic process GO:0017144 6 5 0,000 0,02855735 0,08338468 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02855735 0,0832836 ! organ regeneration GO:0031100 7 5 0,000 0,02855735 0,08318278 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02855735 0,08308219 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02855735 0,08298185 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02855735 0,08288175 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 1,000 0,02909031 0,08432685 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,02909031 0,08422538 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02909031 0,08412415 ! response to calcium ion GO:0051592 81 47 1,000 0,03026988 0,08743016 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03026988 0,08732533 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03026988 0,08722075 ! positive regulation of cyclase activity GO:0031281 103 47 1,000 0,03026988 0,08711642 ! JNK cascade GO:0007254 91 47 1,000 0,03026988 0,08701233 ! methylation GO:0032259 90 47 1,000 0,03026988 0,0869085 ! protein homooligomerization GO:0051260 76 47 1,000 0,03026988 0,08680491 ! mitochondrial transport GO:0006839 82 48 1,000 0,03146819 0,09013389 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03146819 0,09002672 ! positive regulation of lyase activity GO:0051349 104 48 1,000 0,03146819 0,0899198 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,032685 0,09328602 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,032685 0,09317549 ! response to temperature stimulus GO:0009266 76 49 1,000 0,032685 0,09306522 ! endocrine system development GO:0035270 104 49 1,000 0,032685 0,09295522 ! histone modification GO:0016570 91 50 1,000 0,03392006 0,09635378 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03392006 0,09624016 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03417076 0,09683727 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03417076 0,09672334 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03417076 0,09660968 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03417076 0,09649629 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03417076 0,09638316 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03417076 0,0962703 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03417076 0,09615771 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03417076 0,09604537 ! sleep GO:0030431 13 6 0,000 0,03417076 0,0959333 ! response to oxygen radical GO:0000305 11 6 0,000 0,03417076 0,09582149 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03417076 0,09570994 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03417076 0,09559865 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03417076 0,09548762 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03417076 0,09537684 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03417076 0,09526633 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03417076 0,09515606 ! forebrain regionalization GO:0021871 8 6 0,000 0,03417076 0,09504606 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03417076 0,0949363 ! male meiosis GO:0007140 7 6 0,000 0,03417076 0,0948268 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03417076 0,09471756 ! response to zinc ion GO:0010043 9 6 0,000 0,03417076 0,09460856 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03417076 0,09449982 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03417076 0,09439132 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03417076 0,09428307 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03417076 0,09417507 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03417076 0,09406732 ! malate metabolic process GO:0006108 11 6 0,000 0,03417076 0,09395982 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03417076 0,09385256 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03417076 0,09374554 ! protein refolding GO:0042026 15 6 0,000 0,03417076 0,09363877 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03417076 0,09353224 ! opsonization GO:0008228 8 6 0,000 0,03417076 0,09342595 ! mating behavior GO:0007617 7 6 0,000 0,03417076 0,09331991 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03417076 0,0932141 ! equilibrioception GO:0050957 14 6 0,000 0,03417076 0,09310854 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03417076 0,09300321 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03417076 0,09289812 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03417076 0,09279327 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03417076 0,09268866 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03417076 0,09258428 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03417076 0,09248013 ! toxin metabolic process GO:0009404 11 6 0,000 0,03417076 0,09237622 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03417076 0,09227255 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03417076 0,0921691 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03417076 0,09206589 ! nuclear migration GO:0007097 12 6 0,000 0,03417076 0,09196291 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03417076 0,09186016 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03417076 0,09175763 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03417076 0,09165534 ! thymic T cell selection GO:0045061 12 6 0,000 0,03417076 0,09155327 ! protein lipoylation GO:0009249 10 6 0,000 0,03417076 0,09145143 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03417076 0,09134982 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03417076 0,09124843 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03417076 0,09114727 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03417076 0,09104633 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03417076 0,09094562 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03417076 0,09084513 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03417076 0,09074486 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03417076 0,09064481 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03417076 0,09054498 ! hyperosmotic response GO:0006972 9 6 0,000 0,03417076 0,09044537 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03417076 0,09034598 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03417076 0,0902468 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03417076 0,09014785 ! urea metabolic process GO:0019627 7 6 0,000 0,03417076 0,09004911 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03417076 0,08995059 ! neutrophil activation GO:0042119 8 6 0,000 0,03417076 0,08985228 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03417076 0,08975419 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03417076 0,08965631 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03417076 0,08955865 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03417076 0,0894612 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03417076 0,08936396 ! neuron apoptosis GO:0051402 9 6 0,000 0,03417076 0,08926693 ! nucleoside salvage GO:0043174 9 6 0,000 0,03417076 0,08917011 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03417076 0,0890735 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03417076 0,0889771 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03417076 0,08888091 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03417076 0,08878492 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03417076 0,08868915 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03417076 0,08859358 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03417076 0,08849821 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03417076 0,08840305 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03417076 0,0883081 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03417076 0,08821335 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03417076 0,0881188 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03417076 0,08802445 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03417076 0,08793031 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03417076 0,08783637 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03417076 0,08774262 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03417076 0,08764908 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03417076 0,08755574 ! response to UV-C GO:0010225 11 6 0,000 0,03417076 0,0874626 ! astrocyte development GO:0014002 15 6 0,000 0,03417076 0,08736965 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03417076 0,0872769 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03417076 0,08718435 ! interaction with symbiont GO:0051702 13 6 0,000 0,03417076 0,08709199 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03417076 0,08699983 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03417076 0,08690786 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03417076 0,08681609 ! response to copper ion GO:0046688 10 6 0,000 0,03417076 0,08672451 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03417076 0,08663313 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03417076 0,08654194 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03417076 0,08645094 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03417076 0,08636013 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03417076 0,08626951 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03417076 0,08617908 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03417076 0,08608884 ! hair follicle maturation GO:0048820 7 6 0,000 0,03417076 0,08599879 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03417076 0,08590892 ! Schwann cell development GO:0014044 15 6 0,000 0,03417076 0,08581925 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03417076 0,08572976 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03417076 0,08564046 ! subpallium development GO:0021544 10 6 0,000 0,03417076 0,08555134 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03417076 0,08546241 ! histone ubiquitination GO:0016574 8 6 0,000 0,03417076 0,08537366 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03417076 0,0852851 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03417076 0,08519672 ! G2 phase GO:0051319 16 6 0,000 0,03417076 0,08510853 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03417076 0,08502052 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03417076 0,08493269 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03417076 0,08484504 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03417076 0,08475757 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03417076 0,08467028 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03417076 0,08458317 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03417076 0,08449624 ! receptor internalization GO:0031623 10 6 0,000 0,03417076 0,08440949 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03417076 0,08432291 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03417076 0,08423652 ! protein deubiquitination GO:0016579 14 6 0,000 0,03417076 0,0841503 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03417076 0,08406425 ! protein destabilization GO:0031648 9 6 0,000 0,03417076 0,08397839 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03417076 0,08389269 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03417076 0,08380718 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03417076 0,08372183 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03417076 0,08363666 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03417076 0,08355167 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03417076 0,08346684 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03417076 0,08338219 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03417076 0,08329771 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03417076 0,0832134 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03417076 0,08312926 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03417076 0,08304529 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03417076 0,08296149 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03417076 0,08287786 ! catecholamine transport GO:0051937 9 6 0,000 0,03417076 0,0827944 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03417076 0,08271111 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03417076 0,08262798 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03417076 0,08254502 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03417076 0,08246223 ! maternal placenta development GO:0001893 12 6 0,000 0,03417076 0,0823796 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03417076 0,08229714 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03417076 0,08221484 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03417076 0,08213271 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03417076 0,08205074 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03417076 0,08196893 ! positive regulation of binding GO:0051099 78 51 1,000 0,03517311 0,08428934 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03517311 0,08420547 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,03517311 0,08412176 ! vesicle organization GO:0016050 107 51 1,000 0,03517311 0,08403823 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03644391 0,08698813 ! membrane fusion GO:0006944 110 52 1,000 0,03644391 0,08690192 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03644391 0,08681588 ! synapse organization GO:0050808 85 52 1,000 0,03644391 0,08673001 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,03903778 0,09281116 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03903778 0,09271954 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,03903778 0,0926281 ! tRNA transcription GO:0009304 14 7 0,000 0,03975192 0,09422966 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03975192 0,09413692 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03975192 0,09404435 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03975192 0,09395197 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03975192 0,09385977 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03975192 0,09376775 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03975192 0,09367591 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03975192 0,09358426 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03975192 0,09349277 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03975192 0,09340147 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03975192 0,09331035 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03975192 0,0932194 GO:0070193|synaptonemal complex organization, ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03975192 0,09312864 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03975192 0,09303804 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03975192 0,09294763 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03975192 0,09285739 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03975192 0,09276732 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03975192 0,09267743 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03975192 0,09258771 ! glycolipid transport GO:0046836 10 7 0,000 0,03975192 0,09249817 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03975192 0,0924088 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03975192 0,0923196 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03975192 0,09223058 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03975192 0,09214172 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03975192 0,09205304 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03975192 0,09196453 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03975192 0,09187619 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03975192 0,09178801 ! mRNA stabilization GO:0048255 18 7 0,000 0,03975192 0,09170001 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03975192 0,09161217 ! fibril organization GO:0043206 16 7 0,000 0,03975192 0,09152451 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03975192 0,09143701 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03975192 0,09134967 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03975192 0,09126251 ! lipoprotein transport GO:0042953 14 7 0,000 0,03975192 0,09117551 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03975192 0,09108867 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03975192 0,09100201 ! rhythmic behavior GO:0007622 15 7 0,000 0,03975192 0,0909155 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03975192 0,09082916 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03975192 0,09074299 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03975192 0,09065698 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03975192 0,09057113 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03975192 0,09048544 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03975192 0,09039991 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03975192 0,09031455 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03975192 0,09022935 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03975192 0,09014431 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03975192 0,09005942 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03975192 0,0899747 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03975192 0,08989014 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03975192 0,08980574 ! spinal cord patterning GO:0021511 13 7 0,000 0,03975192 0,08972149 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03975192 0,0896374 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03975192 0,08955347 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03975192 0,0894697 ! adrenal gland development GO:0030325 17 7 0,000 0,03975192 0,08938608 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03975192 0,08930262 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03975192 0,08921932 ! ovulation GO:0030728 9 7 0,000 0,03975192 0,08913617 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03975192 0,08905317 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03975192 0,08897033 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03975192 0,08888765 ! microtubule nucleation GO:0007020 20 7 0,000 0,03975192 0,08880511 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03975192 0,08872274 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03975192 0,08864051 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03975192 0,08855843 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03975192 0,08847651 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03975192 0,08839474 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03975192 0,08831312 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03975192 0,08823165 ! galactose metabolic process GO:0006012 13 7 0,000 0,03975192 0,08815033 ! vesicle fusion GO:0006906 17 7 0,000 0,03975192 0,08806916 ! response to dietary excess GO:0002021 8 7 0,000 0,03975192 0,08798814 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03975192 0,08790727 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03975192 0,08782655 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03975192 0,08774597 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03975192 0,08766554 ! purine salvage GO:0043101 10 7 0,000 0,03975192 0,08758526 ! nucleoside transport GO:0015858 8 7 0,000 0,03975192 0,08750513 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03975192 0,08742515 ! parturition GO:0007567 14 7 0,000 0,03975192 0,0873453 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03975192 0,08726561 ! rRNA modification GO:0000154 14 7 0,000 0,03975192 0,08718606 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03975192 0,08710666 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03975192 0,0870274 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03975192 0,08694828 ! macrophage differentiation GO:0030225 11 7 0,000 0,03975192 0,08686931 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03975192 0,08679048 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03975192 0,08671179 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03975192 0,08663325 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03975192 0,08655485 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03975192 0,08647659 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03975192 0,08639847 ! fibrinolysis GO:0042730 10 7 0,000 0,03975192 0,0863205 ! eating behavior GO:0042755 7 7 0,000 0,03975192 0,08624266 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03975192 0,08616496 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03975192 0,08608741 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03975192 0,08600999 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03975192 0,08593271 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03975192 0,08585557 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03975192 0,08577857 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03975192 0,08570171 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03975192 0,08562499 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03975192 0,0855484 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03975192 0,08547195 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03975192 0,08539563 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03975192 0,08531945 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03975192 0,08524341 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03975192 0,08516751 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03975192 0,08509173 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03975192 0,0850161 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03975192 0,08494059 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03975192 0,08486523 ! transcription termination GO:0006353 13 7 0,000 0,03975192 0,08478999 ! response to tumor cell GO:0002347 13 7 0,000 0,03975192 0,08471489 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03975192 0,08463992 ! anaphase GO:0051322 17 7 0,000 0,03975192 0,08456508 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03975192 0,08449038 ! axonal fasciculation GO:0007413 18 7 0,000 0,03975192 0,08441581 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03975192 0,08434137 ! diuresis GO:0030146 12 7 0,000 0,03975192 0,08426706 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03975192 0,08419288 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03975192 0,08411883 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03975192 0,08404491 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03975192 0,08397112 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03975192 0,08389746 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03975192 0,08382393 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03975192 0,08375053 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03975192 0,08367726 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03975192 0,08360412 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03975192 0,0835311 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03975192 0,08345821 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,03975192 0,08338545 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03975192 0,08331281 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03975192 0,0832403 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03975192 0,08316792 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03975192 0,08309566 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03975192 0,08302353 ! adult feeding behavior GO:0008343 9 7 0,000 0,03975192 0,08295153 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03975192 0,08287964 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03975192 0,08280789 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03975192 0,08273625 ! muscle adaptation GO:0043500 14 7 0,000 0,03975192 0,08266474 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03975192 0,08259336 ! retina homeostasis GO:0001895 12 7 0,000 0,03975192 0,0825221 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03975192 0,08245096 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03975192 0,08237994 ! protein prenylation GO:0018342 18 7 0,000 0,03975192 0,08230904 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03975192 0,08223827 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03975192 0,08216762 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03975192 0,08209709 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,04036037 0,0832822 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,04036037 0,08321084 ! RNA elongation GO:0006354 79 55 1,000 0,04036037 0,08313959 ! nuclear export GO:0051168 97 55 1,000 0,04036037 0,08306847 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04169974 0,08575178 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04169974 0,08567855 ! lipid modification GO:0030258 97 57 1,000 0,04305567 0,08838902 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,04305567 0,08831367 ! maintenance of location GO:0051235 118 57 1,000 0,04305567 0,08823845 ! regulation of endocytosis GO:0030100 91 58 1,000 0,04442791 0,09097323 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04530101 0,09268216 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04530101 0,09260342 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04530101 0,09252481 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04530101 0,09244633 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04530101 0,09236799 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04530101 0,09228978 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04530101 0,0922117 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04530101 0,09213375 ! meiotic prophase I GO:0007128 13 8 0,000 0,04530101 0,09205593 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04530101 0,09197825 ! oligopeptide transport GO:0006857 15 8 0,000 0,04530101 0,0919007 ! UTP metabolic process GO:0046051 8 8 0,000 0,04530101 0,09182327 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04530101 0,09174598 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04530101 0,09166882 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04530101 0,09159179 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04530101 0,09151488 ! succinate metabolic process GO:0006105 14 8 0,000 0,04530101 0,09143811 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04530101 0,09136146 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04530101 0,09128495 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04530101 0,09120856 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04530101 0,09113229 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04530101 0,09105616 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04530101 0,09098015 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04530101 0,09090427 ! reflex GO:0060004 16 8 0,000 0,04530101 0,09082852 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04530101 0,09075289 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04530101 0,09067739 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04530101 0,09060202 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04530101 0,09052676 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04530101 0,09045164 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04530101 0,09037664 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04530101 0,09030176 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04530101 0,09022701 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04530101 0,09015238 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04530101 0,09007787 ! histidine metabolic process GO:0006547 16 8 0,000 0,04530101 0,09000349 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04530101 0,08992923 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04530101 0,08985509 ! glycine catabolic process GO:0006546 13 8 0,000 0,04530101 0,08978107 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04530101 0,08970718 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04530101 0,08963341 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04530101 0,08955976 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04530101 0,08948623 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04530101 0,08941282 ! macrophage activation GO:0042116 12 8 0,000 0,04530101 0,08933953 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04530101 0,08926636 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04530101 0,08919331 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04530101 0,08912038 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04530101 0,08904757 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04530101 0,08897488 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04530101 0,0889023 ! osteoblast development GO:0002076 16 8 0,000 0,04530101 0,08882985 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04530101 0,08875751 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04530101 0,08868529 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04530101 0,08861319 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04530101 0,08854121 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04530101 0,08846934 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04530101 0,08839759 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04530101 0,08832595 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04530101 0,08825443 ! intermediate filament organization GO:0045109 12 8 0,000 0,04530101 0,08818303 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04530101 0,08811174 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04530101 0,08804057 ! cellular extravasation GO:0045123 12 8 0,000 0,04530101 0,08796951 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04530101 0,08789857 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04530101 0,08782774 ! response to antibiotic GO:0046677 11 8 0,000 0,04530101 0,08775702 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04530101 0,08768642 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04530101 0,08761594 ! DNA topological change GO:0006265 12 8 0,000 0,04530101 0,08754556 ! response to tropane GO:0014073 15 8 0,000 0,04530101 0,0874753 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04530101 0,08740515 ! melanosome transport GO:0032402 13 8 0,000 0,04530101 0,08733512 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04530101 0,08726519 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04530101 0,08719538 ! mast cell activation GO:0045576 14 8 0,000 0,04530101 0,08712568 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04530101 0,08705609 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04530101 0,08698661 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04530101 0,08691724 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04530101 0,08684799 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04530101 0,08677884 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04530101 0,0867098 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04530101 0,08664088 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04530101 0,08657206 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04530101 0,08650335 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04530101 0,08643475 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04530101 0,08636626 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04530101 0,08629788 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04530101 0,08622961 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04530101 0,08616144 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04530101 0,08609338 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04530101 0,08602543 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04530101 0,08595759 ! hormone catabolic process GO:0042447 17 8 0,000 0,04530101 0,08588985 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04530101 0,08582222 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04530101 0,0857547 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04530101 0,08568728 ! ATP catabolic process GO:0006200 11 8 0,000 0,04530101 0,08561997 ! blastocyst growth GO:0001832 19 8 0,000 0,04530101 0,08555277 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04530101 0,08548567 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04530101 0,08541867 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04530101 0,08535178 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04530101 0,085285 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04530101 0,08521831 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04530101 0,08515174 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04530101 0,08508527 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04530101 0,0850189 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04530101 0,08495263 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04530101 0,08488647 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04530101 0,08482041 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04530101 0,08475445 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04530101 0,0846886 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04530101 0,08462285 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04530101 0,0845572 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04530101 0,08449165 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,04581623 0,08538641 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04581623 0,08532032 ! camera-type eye development GO:0043010 116 60 1,000 0,04722041 0,08786722 ! viral reproductive process GO:0022415 126 62 1,000 0,05007543 0,0931078 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05081822 0,09441593 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05081822 0,09434308 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05081822 0,09427034 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05081822 0,09419771 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05081822 0,09412519 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05081822 0,09405279 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05081822 0,0939805 ! phosphate transport GO:0006817 19 9 0,000 0,05081822 0,09390832 ! reproductive behavior GO:0019098 19 9 0,000 0,05081822 0,09383625 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05081822 0,09376429 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05081822 0,09369244 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05081822 0,0936207 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05081822 0,09354906 ! GTP metabolic process GO:0046039 9 9 0,000 0,05081822 0,09347754 ! RNA methylation GO:0001510 15 9 0,000 0,05081822 0,09340613 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05081822 0,09333483 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05081822 0,09326364 ! artery development GO:0060840 24 9 0,000 0,05081822 0,09319255 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05081822 0,09312157 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05081822 0,09305071 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05081822 0,09297995 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05081822 0,09290929 ! chemosensory behavior GO:0007635 20 9 0,000 0,05081822 0,09283875 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05081822 0,09276831 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05081822 0,09269797 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05081822 0,09262775 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05081822 0,09255763 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05081822 0,09248762 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05081822 0,09241771 ! protein targeting to ER GO:0045047 22 9 0,000 0,05081822 0,09234791 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05081822 0,09227821 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05081822 0,09220862 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05081822 0,09213913 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05081822 0,09206975 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05081822 0,09200047 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05081822 0,0919313 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05081822 0,09186223 ! mannose metabolic process GO:0006013 13 9 0,000 0,05081822 0,09179326 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05081822 0,0917244 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05081822 0,09165564 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05081822 0,09158699 ! receptor clustering GO:0043113 18 9 0,000 0,05081822 0,09151843 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05081822 0,09144998 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05081822 0,09138164 ! ruffle organization GO:0031529 15 9 0,000 0,05081822 0,09131339 ! retinol metabolic process GO:0042572 18 9 0,000 0,05081822 0,09124524 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05081822 0,0911772 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05081822 0,09110926 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05081822 0,09104142 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05081822 0,09097368 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05081822 0,09090604 ! segment specification GO:0007379 13 9 0,000 0,05081822 0,0908385 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05081822 0,09077107 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05081822 0,09070373 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05081822 0,09063649 ! response to amine stimulus GO:0014075 13 9 0,000 0,05081822 0,09056935 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05081822 0,09050232 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05081822 0,09043538 ! erythrocyte development GO:0048821 15 9 0,000 0,05081822 0,09036853 ! gas homeostasis GO:0033483 16 9 0,000 0,05081822 0,09030179 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05081822 0,09023515 ! renal water homeostasis GO:0003091 14 9 0,000 0,05081822 0,0901686 ! postreplication repair GO:0006301 22 9 0,000 0,05081822 0,09010216 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05081822 0,09003581 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05081822 0,08996956 ! icosanoid secretion GO:0032309 15 9 0,000 0,05081822 0,0899034 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05081822 0,08983735 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05081822 0,08977139 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05081822 0,08970552 ! regulation of cell division GO:0051302 15 9 0,000 0,05081822 0,08963976 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05081822 0,08957409 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05081822 0,08950851 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05081822 0,08944303 ! sterol catabolic process GO:0016127 11 9 0,000 0,05081822 0,08937765 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05081822 0,08931237 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05081822 0,08924717 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05081822 0,08918208 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05081822 0,08911708 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05081822 0,08905217 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05081822 0,08898736 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05081822 0,08892264 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05081822 0,08885801 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05081822 0,08879348 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05081822 0,08872905 ! purine base metabolic process GO:0006144 21 9 0,000 0,05081822 0,0886647 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05081822 0,08860045 ! pigment granule transport GO:0051904 17 9 0,000 0,05081822 0,0885363 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05081822 0,08847223 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05081822 0,08840826 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05081822 0,08834438 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05081822 0,0882806 ! mitochondrion localization GO:0051646 15 9 0,000 0,05081822 0,0882169 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,05299118 0,09192269 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 1,000 0,05299118 0,09185646 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,05447127 0,09435412 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05596588 0,09687331 ! secondary metabolic process GO:0019748 116 66 1,000 0,05596588 0,09680367 ! cell projection assembly GO:0030031 120 66 1,000 0,05596588 0,09673413 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05630372 0,09724821 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05630372 0,09717845 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05630372 0,09710879 ! synapsis GO:0007129 13 10 0,000 0,05630372 0,09703922 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05630372 0,09696976 ! N-glycan processing GO:0006491 20 10 0,000 0,05630372 0,0969004 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05630372 0,09683113 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05630372 0,09676197 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05630372 0,0966929 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05630372 0,09662393 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05630372 0,09655507 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05630372 0,09648629 ! androgen metabolic process GO:0008209 17 10 0,000 0,05630372 0,09641762 ! phospholipid efflux GO:0033700 16 10 0,000 0,05630372 0,09634904 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05630372 0,09628057 ! lung alveolus development GO:0048286 26 10 0,000 0,05630372 0,09621218 ! pathogenesis GO:0009405 13 10 0,000 0,05630372 0,0961439 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05630372 0,09607571 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05630372 0,09600762 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05630372 0,09593963 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05630372 0,09587173 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05630372 0,09580393 ! endoderm development GO:0007492 16 10 0,000 0,05630372 0,09573622 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05630372 0,09566861 ! arginine catabolic process GO:0006527 13 10 0,000 0,05630372 0,0956011 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05630372 0,09553368 ! proline metabolic process GO:0006560 13 10 0,000 0,05630372 0,09546635 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05630372 0,09539912 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05630372 0,09533199 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05630372 0,09526495 ! V(D)J recombination GO:0033151 28 10 0,000 0,05630372 0,095198 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05630372 0,09513115 ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05630372 0,09506439 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05630372 0,09499773 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05630372 0,09493115 ! multicellular organism growth GO:0035264 18 10 0,000 0,05630372 0,09486468 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05630372 0,09479829 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05630372 0,094732 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05630372 0,0946658 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05630372 0,09459969 ! macroautophagy GO:0016236 17 10 0,000 0,05630372 0,09453368 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05630372 0,09446775 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05630372 0,09440192 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05630372 0,09433618 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05630372 0,09427053 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05630372 0,09420498 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05630372 0,09413951 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05630372 0,09407414 ! brain morphogenesis GO:0048854 23 10 0,000 0,05630372 0,09400885 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05630372 0,09394366 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05630372 0,09387856 ! response to dsRNA GO:0043331 20 10 0,000 0,05630372 0,09381354 ! DNA ligation GO:0006266 19 10 0,000 0,05630372 0,09374862 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05630372 0,09368379 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05630372 0,09361904 ! melanosome localization GO:0032400 16 10 0,000 0,05630372 0,09355439 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05630372 0,09348982 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05630372 0,09342535 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05630372 0,09336096 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05630372 0,09329666 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05630372 0,09323245 ! mRNA cleavage GO:0006379 17 10 0,000 0,05630372 0,09316833 ! protein sumoylation GO:0016925 15 10 0,000 0,05630372 0,0931043 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05630372 0,09304035 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05630372 0,0929765 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05630372 0,09291273 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05630372 0,09284904 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05630372 0,09278545 ! prophase GO:0051324 15 10 0,000 0,05630372 0,09272194 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05630372 0,09265852 ! apical protein localization GO:0045176 15 10 0,000 0,05630372 0,09259519 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05630372 0,09253194 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05630372 0,09246878 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05630372 0,0924057 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05630372 0,09234271 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05630372 0,09227981 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05630372 0,09221699 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05630372 0,09215426 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05630372 0,09209161 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05630372 0,09202905 ! detection of calcium ion GO:0005513 23 10 0,000 0,05630372 0,09196657 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05630372 0,09190418 ! blastocyst formation GO:0001825 17 10 0,000 0,05630372 0,09184187 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05630372 0,09177965 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05630372 0,09171751 ! activation of innate immune response GO:0002218 12 10 0,000 0,05630372 0,09165545 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05630372 0,09159348 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05630372 0,09153159 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05630372 0,09146979 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05630372 0,09140807 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05630372 0,09134643 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,0574748 0,09318354 ! activation of MAPK activity GO:0000187 115 67 1,000 0,0574748 0,09312079 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,0574748 0,09305812 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,0574748 0,09299554 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,0574748 0,09293304 ! viral reproduction GO:0016032 134 68 1,000 0,05899782 0,0953316 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06053472 0,09774935 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06053472 0,09768379 ! antigen processing and presentation GO:0019882 104 69 1,000 0,06053472 0,09761832 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06175771 0,09952381 ! respiratory burst GO:0045730 17 11 0,000 0,06175771 0,09945719 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06175771 0,09939067 ! neuron fate specification GO:0048665 17 11 0,000 0,06175771 0,09932423 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06175771 0,09925788 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06175771 0,09919162 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,06175771 0,09912545 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06175771 0,09905936 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06175771 0,09899337 ! response to pain GO:0048265 24 11 0,000 0,06175771 0,09892746 ! T cell proliferation GO:0042098 26 11 0,000 0,06175771 0,09886164 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06175771 0,09879591 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06175771 0,09873026 ! bone resorption GO:0045453 16 11 0,000 0,06175771 0,09866471 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06175771 0,09859923 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06175771 0,09853385 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06175771 0,09846855 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06175771 0,09840334 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06175771 0,09833822 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06175771 0,09827318 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06175771 0,09820823 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06175771 0,09814336 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06175771 0,09807858 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06175771 0,09801388 ! lipid digestion GO:0044241 18 11 0,000 0,06175771 0,09794927 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06175771 0,09788475 ! UV protection GO:0009650 19 11 0,000 0,06175771 0,09782031 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06175771 0,09775595 ! temperature homeostasis GO:0001659 17 11 0,000 0,06175771 0,09769168 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06175771 0,09762749 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06175771 0,09756339 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06175771 0,09749937 ! regulation of organ growth GO:0046620 13 11 0,000 0,06175771 0,09743544 ! pigment granule localization GO:0051875 20 11 0,000 0,06175771 0,09737159 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06175771 0,09730782 ! vasoconstriction GO:0042310 18 11 0,000 0,06175771 0,09724414 ! embryonic axis specification GO:0000578 18 11 0,000 0,06175771 0,09718054 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06175771 0,09711702 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06175771 0,09705359 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06175771 0,09699024 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06175771 0,09692697 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06175771 0,09686379 ! zymogen activation GO:0031638 15 11 0,000 0,06175771 0,09680068 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06175771 0,09673766 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06175771 0,09667472 ! nucleosome positioning GO:0016584 15 11 0,000 0,06175771 0,09661186 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06175771 0,09654909 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06175771 0,09648639 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06175771 0,09642378 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06175771 0,09636125 ! acid secretion GO:0046717 18 11 0,000 0,06175771 0,0962988 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06175771 0,09623643 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06175771 0,09617414 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06175771 0,09611193 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06175771 0,0960498 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06175771 0,09598776 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06175771 0,09592579 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06175771 0,0958639 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06175771 0,09580209 ! germ cell migration GO:0008354 25 11 0,000 0,06175771 0,09574036 ! embryonic gut development GO:0048566 15 11 0,000 0,06175771 0,09567872 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06175771 0,09561715 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06175771 0,09555566 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06175771 0,09549425 ! defense response to fungus GO:0050832 13 11 0,000 0,06175771 0,09543291 ! developmental induction GO:0031128 19 11 0,000 0,06175771 0,09537166 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06175771 0,09531049 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06175771 0,09524939 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06175771 0,09518837 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06175771 0,09512743 ! nucleus localization GO:0051647 19 11 0,000 0,06175771 0,09506657 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06175771 0,09500578 ! humoral immune response GO:0006959 109 71 1,000 0,06364933 0,09785322 ! B cell activation GO:0042113 160 71 1,000 0,06364933 0,09779074 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,06364933 0,09772833 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06522664 0,10008628 ! carbohydrate transport GO:0008643 110 72 1,000 0,06522664 0,10002249 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06522664 0,09995878 ! learning or memory GO:0007611 147 73 1,000 0,066817 0,10233081 ! regulation of blood pressure GO:0008217 125 73 1,000 0,066817 0,10226571 ! axon guidance GO:0007411 139 73 1,000 0,066817 0,1022007 ! fertilization GO:0009566 90 73 1,000 0,066817 0,10213577 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06718035 0,10262599 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06718035 0,10256087 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06718035 0,10249583 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06718035 0,10243088 ! cartilage condensation GO:0001502 20 12 0,000 0,06718035 0,10236601 ! mating GO:0007618 17 12 0,000 0,06718035 0,10230122 ! protein complex disassembly GO:0043241 27 12 0,000 0,06718035 0,10223652 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06718035 0,10217189 ! hippocampus development GO:0021766 26 12 0,000 0,06718035 0,10210735 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06718035 0,10204289 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06718035 0,10197851 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06718035 0,10191421 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06718035 0,10184999 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06718035 0,10178585 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06718035 0,10172179 ! drug transport GO:0015893 16 12 0,000 0,06718035 0,10165782 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06718035 0,10159392 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06718035 0,10153011 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06718035 0,10146637 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06718035 0,10140272 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06718035 0,10133914 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06718035 0,10127565 ! forebrain cell migration GO:0021885 21 12 0,000 0,06718035 0,10121223 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06718035 0,10114889 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06718035 0,10108564 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06718035 0,10102246 ! entry into host cell GO:0030260 32 12 0,000 0,06718035 0,10095936 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,06718035 0,10089634 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06718035 0,10083339 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06718035 0,10077053 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06718035 0,10070775 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06718035 0,10064504 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06718035 0,10058241 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06718035 0,10051986 ! protein homotetramerization GO:0051289 21 12 0,000 0,06718035 0,10045738 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06718035 0,10039499 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06718035 0,10033267 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06718035 0,10027043 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06718035 0,10020826 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06718035 0,10014618 ! cranial nerve development GO:0021545 20 12 0,000 0,06718035 0,10008417 ! fucose catabolic process GO:0019317 22 12 0,000 0,06718035 0,10002223 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06718035 0,09996038 ! histone methylation GO:0016571 26 12 0,000 0,06718035 0,0998986 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06718035 0,09983689 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06718035 0,09977527 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06718035 0,09971371 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06718035 0,09965224 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06718035 0,09959084 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06718035 0,09952951 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06718035 0,09946827 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06718035 0,09940709 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06718035 0,09934599 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06718035 0,09928497 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06718035 0,09922402 ! response to cold GO:0009409 17 12 0,000 0,06718035 0,09916315 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06718035 0,09910235 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06718035 0,09904162 ! organelle localization GO:0051640 136 74 1,000 0,06842022 0,10080774 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,0700361 0,10312536 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,0700361 0,10306229 ! rhythmic process GO:0048511 128 75 1,000 0,0700361 0,10299929 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,07166443 0,10532964 ! regulation of catabolic process GO:0009894 161 76 1,000 0,07166443 0,10526534 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07257184 0,10653315 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07257184 0,1064682 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07257184 0,10640332 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07257184 0,10633851 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07257184 0,10627379 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07257184 0,10620915 ! lipid localization GO:0010876 28 13 0,000 0,07257184 0,10614458 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07257184 0,1060801 ! organelle fusion GO:0048284 32 13 0,000 0,07257184 0,10601569 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07257184 0,10595136 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07257184 0,10588711 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07257184 0,10582293 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07257184 0,10575884 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07257184 0,10569482 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07257184 0,10563088 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07257184 0,10556701 ! methionine metabolic process GO:0006555 27 13 0,000 0,07257184 0,10550323 ! plasma membrane organization GO:0007009 24 13 0,000 0,07257184 0,10543952 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07257184 0,10537588 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07257184 0,10531233 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07257184 0,10524885 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! response to X-ray GO:0010165 25 13 0,000 0,07257184 0,10518545 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07257184 0,10512212 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07257184 0,10505887 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07257184 0,1049957 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07257184 0,1049326 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07257184 0,10486957 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07257184 0,10480663 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07257184 0,10474376 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07257184 0,10468096 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07257184 0,10461824 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07257184 0,10455559 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07257184 0,10449302 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07257184 0,10443053 ! ribosome assembly GO:0042255 17 13 0,000 0,07257184 0,10436811 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07257184 0,10430576 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07257184 0,10424349 ! chromatin silencing GO:0006342 26 13 0,000 0,07257184 0,10418129 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07257184 0,10411917 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07257184 0,10405712 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07257184 0,10399514 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07257184 0,10393324 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07257184 0,10387141 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07257184 0,10380966 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07257184 0,10374797 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07257184 0,10368637 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07257184 0,10362483 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07257184 0,10356337 ! embryonic placenta development GO:0001892 23 13 0,000 0,07257184 0,10350198 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07257184 0,10344066 ! actin filament polymerization GO:0030041 24 13 0,000 0,07257184 0,10337942 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07257184 0,10331825 ! acrosome reaction GO:0007340 18 13 0,000 0,07257184 0,10325715 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,07330503 0,10423872 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,0749577 0,10652583 ! rRNA transcription GO:0009303 25 14 0,000 0,07793234 0,11068784 ! lactation GO:0007595 26 14 0,000 0,07793234 0,11062254 ! reproductive cellular process GO:0048610 20 14 0,000 0,07793234 0,11055731 ! tRNA modification GO:0006400 20 14 0,000 0,07793234 0,11049217 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07793234 0,11042709 ! regulation of S phase GO:0033261 23 14 0,000 0,07793234 0,1103621 ! water transport GO:0006833 21 14 0,000 0,07793234 0,11029718 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07793234 0,11023234 ! non-recombinational repair GO:0000726 25 14 0,000 0,07793234 0,11016757 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07793234 0,11010288 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07793234 0,11003827 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07793234 0,10997373 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07793234 0,10990926 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07793234 0,10984488 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07793234 0,10978056 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07793234 0,10971633 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07793234 0,10965217 ! arginine metabolic process GO:0006525 17 14 0,000 0,07793234 0,10958808 ! regulation of heart rate GO:0002027 24 14 0,000 0,07793234 0,10952407 ! organic alcohol transport GO:0015850 29 14 0,000 0,07793234 0,10946013 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07793234 0,10939627 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07793234 0,10933248 ! embryo implantation GO:0007566 30 14 0,000 0,07793234 0,10926877 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07793234 0,10920513 ! L-amino acid transport GO:0015807 30 14 0,000 0,07793234 0,10914156 ! bone mineralization GO:0030282 17 14 0,000 0,07793234 0,10907807 ! stem cell development GO:0048864 43 14 0,000 0,07793234 0,10901465 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07793234 0,10895131 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07793234 0,10888804 ! cerebellum development GO:0021549 21 14 0,000 0,07793234 0,10882484 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07793234 0,10876172 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07793234 0,10869867 ! cofactor transport GO:0051181 26 14 0,000 0,07793234 0,10863569 ! NADP metabolic process GO:0006739 24 14 0,000 0,07793234 0,10857279 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07793234 0,10850996 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07793234 0,1084472 ! intestinal absorption GO:0050892 25 14 0,000 0,07793234 0,10838451 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07793234 0,1083219 ! oxygen transport GO:0015671 21 14 0,000 0,07793234 0,10825936 ! male genitalia development GO:0030539 24 14 0,000 0,07793234 0,10819689 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07793234 0,10813449 ! regulation of axon extension GO:0030516 37 14 0,000 0,07793234 0,10807216 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07793234 0,10800991 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,07829849 0,1084549 ! muscle cell differentiation GO:0042692 159 80 1,000 0,07829849 0,10839249 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,08168526 0,11301595 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,08168526 0,112951 ! response to nutrient GO:0007584 125 82 1,000 0,08168526 0,11288612 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,08168526 0,11282132 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08326203 0,11493313 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,08326203 0,11486723 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08326203 0,1148014 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08326203 0,11473565 ! copper ion transport GO:0006825 20 15 0,000 0,08326203 0,11466998 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08326203 0,11460438 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08326203 0,11453885 ! sulfate transport GO:0008272 23 15 0,000 0,08326203 0,1144734 ! response to cAMP GO:0051591 22 15 0,000 0,08326203 0,11440802 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08326203 0,11434272 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08326203 0,11427749 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08326203 0,11421234 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08326203 0,11414726 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08326203 0,11408226 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08326203 0,11401733 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08326203 0,11395247 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08326203 0,11388769 ! vesicle coating GO:0006901 33 15 0,000 0,08326203 0,11382298 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08326203 0,11375835 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08326203 0,11369378 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08326203 0,1136293 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08326203 0,11356488 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08326203 0,11350054 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08326203 0,11343627 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08326203 0,11337207 ! histone deacetylation GO:0016575 20 15 0,000 0,08326203 0,11330795 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08326203 0,11324389 ! tissue regeneration GO:0042246 26 15 0,000 0,08326203 0,11317991 ! water homeostasis GO:0030104 27 15 0,000 0,08326203 0,11311601 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08326203 0,11305217 ! muscle maintenance GO:0046716 26 15 0,000 0,08326203 0,11298841 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08326203 0,11292472 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08326203 0,1128611 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08326203 0,11279755 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08326203 0,11273407 ! cell killing GO:0001906 29 15 0,000 0,08326203 0,11267067 ! detection of bacterium GO:0016045 18 15 0,000 0,08326203 0,11260733 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08326203 0,11254407 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08326203 0,11248088 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08326203 0,11241776 ! peptide hormone processing GO:0016486 23 15 0,000 0,08326203 0,11235471 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08339543 0,11247164 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,08511654 0,11472852 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,08684842 0,11699736 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08856109 0,11923783 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08856109 0,11917114 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08856109 0,11910452 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08856109 0,11903799 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08856109 0,11897152 ! bone remodeling GO:0046849 27 16 0,000 0,08856109 0,11890513 ! filopodium assembly GO:0046847 32 16 0,000 0,08856109 0,11883881 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,08856109 0,11877257 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08856109 0,1187064 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08856109 0,11864031 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08856109 0,11857429 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08856109 0,11850834 ! startle response GO:0001964 28 16 0,000 0,08856109 0,11844246 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08856109 0,11837666 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08856109 0,11831094 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08856109 0,11824528 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08856109 0,1181797 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08856109 0,11811419 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08856109 0,11804875 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08856109 0,11798339 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08856109 0,11791809 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08856109 0,11785287 ! response to osmotic stress GO:0006970 25 16 0,000 0,08856109 0,11778772 ! lysosomal transport GO:0007041 26 16 0,000 0,08856109 0,11772265 ! fructose metabolic process GO:0006000 25 16 0,000 0,08856109 0,11765764 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08856109 0,11759271 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,08856109 0,11752785 ! axon cargo transport GO:0008088 43 16 0,000 0,08856109 0,11746306 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08856109 0,11739834 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,08856109 0,1173337 ! DNA replication initiation GO:0006270 27 16 0,000 0,08856109 0,11726912 ! neuron recognition GO:0008038 35 16 0,000 0,08856109 0,11720462 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08856109 0,11714018 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08856109 0,11707582 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08856109 0,11701153 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08856109 0,11694731 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08856109 0,11688316 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08856109 0,11681908 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08856109 0,11675507 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08856109 0,11669113 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08856109 0,11662725 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08856109 0,11656345 ! amine biosynthetic process GO:0009309 138 86 1,000 0,08859087 0,11653889 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,09034373 0,11877978 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 1,000 0,09034373 0,11871491 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 1,000 0,09210681 0,1209656 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0938297 0,12316108 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0938297 0,12309393 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0938297 0,12302685 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0938297 0,12295984 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0938297 0,1228929 ! signal complex assembly GO:0007172 41 17 0,000 0,0938297 0,12282604 ! endothelial cell migration GO:0043542 28 17 0,000 0,0938297 0,12275925 ! inositol metabolic process GO:0006020 28 17 0,000 0,0938297 0,12269254 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0938297 0,12262589 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0938297 0,12255932 ! glial cell development GO:0021782 27 17 0,000 0,0938297 0,12249282 ! limbic system development GO:0021761 36 17 0,000 0,0938297 0,12242639 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0938297 0,12236004 ! adult walking behavior GO:0007628 33 17 0,000 0,0938297 0,12229375 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0938297 0,12222754 ! heart looping GO:0001947 30 17 0,000 0,0938297 0,1221614 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0938297 0,12209533 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0938297 0,12202933 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,0938297 0,12196341 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0938297 0,12189755 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0938297 0,12183177 ! glycine metabolic process GO:0006544 28 17 0,000 0,0938297 0,12176605 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0938297 0,12170041 ! NAD metabolic process GO:0019674 29 17 0,000 0,0938297 0,12163484 ! membrane budding GO:0006900 37 17 0,000 0,0938297 0,12156934 ! DNA integration GO:0015074 29 17 0,000 0,0938297 0,12150391 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0938297 0,12143855 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0938297 0,12137326 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0938297 0,12130804 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0938297 0,12124289 ! genitalia development GO:0048806 30 17 0,000 0,0938297 0,12117781 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0938297 0,1211128 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0938297 0,12104786 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0938297 0,12098299 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0938297 0,12091819 ! steroid catabolic process GO:0006706 31 17 0,000 0,0938297 0,12085346 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0938297 0,1207888 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0938297 0,12072421 ! gas transport GO:0015669 25 17 0,000 0,0938297 0,12065968 ! organic cation transport GO:0015695 31 17 0,000 0,0938297 0,12059523 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0938297 0,12053084 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0938297 0,12046652 ! microspike assembly GO:0030035 36 17 0,000 0,0938297 0,12040227 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0938297 0,12033809 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,09387994 0,12033838 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,09566295 0,1225586 ! sterol metabolic process GO:0016125 152 91 1,000 0,09745566 0,12478889 ! response to protein stimulus GO:0051789 149 91 1,000 0,09745566 0,12472251 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09906803 0,1267186 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09906803 0,12665126 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09906803 0,126584 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09906803 0,12651681 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09906803 0,1264497 ! memory GO:0007613 31 18 0,000 0,09906803 0,12638265 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09906803 0,12631568 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09906803 0,12624877 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09906803 0,12618194 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09906803 0,12611517 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09906803 0,12604848 ! response to retinoic acid GO:0032526 26 18 0,000 0,09906803 0,12598186 ! response to fungus GO:0009620 21 18 0,000 0,09906803 0,12591531 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09906803 0,12584883 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09906803 0,12578242 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09906803 0,12571608 ! vitamin transport GO:0051180 27 18 0,000 0,09906803 0,1256498 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09906803 0,1255836 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09906803 0,12551747 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09906803 0,12545141 ! nerve development GO:0021675 28 18 0,000 0,09906803 0,12538542 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09906803 0,12531949 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,10106953 0,12778418 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,10106953 0,12771707 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,10289035 0,1299497 ! female pregnancy GO:0007565 164 94 1,000 0,10289035 0,12988152 ! protein secretion GO:0009306 39 19 0,000 0,10427625 0,13156196 ! positive regulation of translation GO:0045727 30 19 0,000 0,10427625 0,131493 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10427625 0,13142412 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10427625 0,13135532 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10427625 0,13128658 ! skin development GO:0043588 36 19 0,000 0,10427625 0,13121791 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10427625 0,13114932 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10427625 0,1310808 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10427625 0,13101235 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10427625 0,13094397 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10427625 0,13087567 ! cerebral cortex development GO:0021987 36 19 0,000 0,10427625 0,13080743 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10427625 0,13073927 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10427625 0,13067117 ! heme metabolic process GO:0042168 36 19 0,000 0,10427625 0,13060315 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10427625 0,1305352 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10427625 0,13046732 ! peptide cross-linking GO:0018149 37 19 0,000 0,10427625 0,13039951 ! heart process GO:0003015 30 19 0,000 0,10427625 0,13033177 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10427625 0,1302641 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,10427625 0,1301965 ! G1 phase GO:0051318 40 19 0,000 0,10427625 0,13012897 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10427625 0,13006151 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10427625 0,12999412 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10427625 0,1299268 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10427625 0,12985955 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10427625 0,12979237 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10427625 0,12972526 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10427625 0,12965822 ! cilium assembly GO:0042384 37 19 0,000 0,10427625 0,12959125 ! positive regulation of immune response GO:0050778 156 96 1,000 0,10655893 0,13235972 ! hormone metabolic process GO:0042445 157 97 1,000 0,10840636 0,13458499 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10945453 0,13581619 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10945453 0,13574619 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10945453 0,13567625 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10945453 0,13560638 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10945453 0,13553659 ! response to vitamin GO:0033273 31 20 0,000 0,10945453 0,13546687 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10945453 0,13539722 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10945453 0,13532765 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10945453 0,13525814 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10945453 0,13518871 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10945453 0,13511934 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10945453 0,13505005 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10945453 0,13498083 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10945453 0,13491168 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10945453 0,1348426 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10945453 0,13477359 ! body fluid secretion GO:0007589 31 20 0,000 0,10945453 0,13470465 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10945453 0,13463579 ! stem cell differentiation GO:0048863 53 20 0,000 0,10945453 0,13456699 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10945453 0,13449826 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10945453 0,13442961 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10945453 0,13436102 ! sensory perception of pain GO:0019233 30 20 0,000 0,10945453 0,1342925 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10945453 0,13422406 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10945453 0,13415568 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10945453 0,13408737 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10945453 0,13401913 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10945453 0,13395097 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10945453 0,13388287 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10945453 0,13381484 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10945453 0,13374688 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10945453 0,13367898 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10945453 0,13361116 ! actin filament-based movement GO:0030048 43 20 0,000 0,10945453 0,13354341 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10945453 0,13347572 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10945453 0,1334081 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10945453 0,13334056 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,10945453 0,13327308 ! response to virus GO:0009615 160 98 1,000 0,11026234 0,13418877 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,11212672 0,13638872 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,11212672 0,1363198 ! regulation of cell killing GO:0031341 42 21 0,000 0,11460305 0,13926007 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11460305 0,13918977 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11460305 0,13911954 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11460305 0,13904939 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11460305 0,1389793 ! axis specification GO:0009798 38 21 0,000 0,11460305 0,13890928 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11460305 0,13883934 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11460305 0,13876947 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11460305 0,13869966 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11460305 0,13862993 ! cytolysis GO:0019835 24 21 0,000 0,11460305 0,13856027 ! vasodilation GO:0042311 39 21 0,000 0,11460305 0,13849067 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11460305 0,13842115 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11460305 0,1383517 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11460305 0,13828231 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11460305 0,138213 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11460305 0,13814375 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11460305 0,13807458 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11460305 0,13800547 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11460305 0,13793643 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,11972197 0,14402553 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11972197 0,14395355 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11972197 0,14388165 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11972197 0,14380981 ! microtubule-based transport GO:0010970 54 22 0,000 0,11972197 0,14373805 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11972197 0,14366636 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11972197 0,14359474 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11972197 0,1435232 ! sensory perception of taste GO:0050909 28 22 0,000 0,11972197 0,14345172 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,11972197 0,14338032 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11972197 0,14330898 ! vacuolar transport GO:0007034 36 22 0,000 0,11972197 0,14323772 ! lysosome organization GO:0007040 41 22 0,000 0,11972197 0,14316653 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11972197 0,14309541 ! fucose metabolic process GO:0006004 39 22 0,000 0,11972197 0,14302436 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11972197 0,14295338 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11972197 0,14288247 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11972197 0,14281163 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11972197 0,14274086 ! sarcomere organization GO:0045214 30 22 0,000 0,11972197 0,14267016 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11972197 0,14259953 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11972197 0,14252897 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11972197 0,14245848 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12481146 0,14844112 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12481146 0,14836778 ! gluconeogenesis GO:0006094 33 23 0,000 0,12481146 0,14829451 ! viral genome replication GO:0019079 41 23 0,000 0,12481146 0,14822131 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12481146 0,14814819 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12481146 0,14807514 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12481146 0,14800216 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12481146 0,14792925 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12481146 0,14785642 ! visual behavior GO:0007632 42 23 0,000 0,12481146 0,14778365 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12481146 0,14771096 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12481146 0,14763834 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,12481146 0,14756579 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12481146 0,14749331 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12481146 0,1474209 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12481146 0,14734857 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12481146 0,1472763 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,12481146 0,14720411 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12481146 0,14713199 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12481146 0,14705993 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12481146 0,14698795 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12481146 0,14691604 ! fatty acid transport GO:0015908 44 23 0,000 0,12481146 0,1468442 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12481146 0,14677243 ! cell-cell recognition GO:0009988 25 23 0,000 0,12481146 0,14670072 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12481146 0,14662909 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12481146 0,14655753 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,12481146 0,14648604 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12481146 0,14641462 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1298717 0,15227647 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1298717 0,1522023 ! vesicle docking GO:0048278 47 24 0,000 0,1298717 0,1521282 ! spinal cord development GO:0021510 47 24 0,000 0,1298717 0,15205417 ! vacuole organization GO:0007033 43 24 0,000 0,1298717 0,15198021 ! digestive system process GO:0022600 39 24 0,000 0,1298717 0,15190633 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,1298717 0,15183252 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1298717 0,15175877 ! membrane depolarization GO:0051899 39 24 0,000 0,1298717 0,1516851 ! pallium development GO:0021543 49 24 0,000 0,1298717 0,15161151 ! pentose metabolic process GO:0019321 35 24 0,000 0,1298717 0,15153798 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,1298717 0,15146453 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1298717 0,15139114 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1298717 0,15131783 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1298717 0,15124459 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1298717 0,15117142 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1298717 0,15109832 ! regulation of amine transport GO:0051952 40 24 0,000 0,1298717 0,15102529 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13490285 0,15680012 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13490285 0,15672441 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13490285 0,15664877 ! phototransduction GO:0007602 33 25 0,000 0,13490285 0,15657321 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13490285 0,15649771 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,13490285 0,15642229 ! sperm motility GO:0030317 31 25 0,000 0,13490285 0,15634694 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13490285 0,15627167 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,13490285 0,15619647 ! receptor metabolic process GO:0043112 46 25 0,000 0,13490285 0,15612134 ! chromosome condensation GO:0030261 45 25 0,000 0,13490285 0,15604628 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13490285 0,15597129 ! neural crest cell development GO:0014032 54 25 0,000 0,13490285 0,15589638 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 0,000 0,13490285 0,15582153 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13490285 0,15574676 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13490285 0,15567207 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,13490285 0,15559744 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13490285 0,15552288 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13490285 0,1554484 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13490285 0,15537399 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13490285 0,15529964 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13490285 0,15522537 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13490285 0,15515117 ! telomere organization GO:0032200 43 25 0,000 0,13490285 0,15507705 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,13490285 0,15500299 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13990507 0,1606738 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13990507 0,16059714 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13990507 0,16052056 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13990507 0,16044405 ! initiation of viral infection GO:0019059 57 26 0,000 0,13990507 0,16036761 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13990507 0,16029124 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13990507 0,16021495 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13990507 0,16013873 ! tube lumen formation GO:0035148 50 26 0,000 0,13990507 0,16006258 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13990507 0,15998651 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,13990507 0,1599105 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13990507 0,15983457 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,13990507 0,15975871 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13990507 0,15968293 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13990507 0,15960721 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13990507 0,15953157 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13990507 0,159456 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13990507 0,1593805 ! blastocyst development GO:0001824 49 26 0,000 0,13990507 0,15930507 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13990507 0,15922971 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13990507 0,15915442 ! neuron fate commitment GO:0048663 48 27 0,000 0,14487854 0,16473429 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,14487854 0,16465648 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14487854 0,16457874 ! iron ion transport GO:0006826 59 27 0,000 0,14487854 0,16450107 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14487854 0,16442347 ! superoxide metabolic process GO:0006801 38 27 0,000 0,14487854 0,16434595 ! fat cell differentiation GO:0045444 50 27 0,000 0,14487854 0,1642685 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14487854 0,16419113 ! autophagy GO:0006914 41 27 0,000 0,14487854 0,16411382 ! primary neural tube formation GO:0014020 51 27 0,000 0,14487854 0,16403659 ! base-excision repair GO:0006284 41 27 0,000 0,14487854 0,16395944 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14487854 0,16388235 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14487854 0,16380534 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14487854 0,1637284 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14487854 0,16365153 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14487854 0,16357474 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14982341 0,16907839 ! circadian rhythm GO:0007623 50 28 0,000 0,14982341 0,16899912 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14982341 0,16891992 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14982341 0,16884081 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14982341 0,16876176 ! synaptogenesis GO:0007416 42 28 0,000 0,14982341 0,16868279 ! lipid oxidation GO:0034440 43 28 0,000 0,14982341 0,16860389 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14982341 0,16852507 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14982341 0,16844632 ! translational initiation GO:0006413 65 29 0,000 0,15473985 0,17389261 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15473985 0,17381142 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15473985 0,17373032 ! regulation of pH GO:0006885 43 29 0,000 0,15473985 0,17364929 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15473985 0,17356833 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15473985 0,17348745 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15473985 0,17340665 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15473985 0,17332592 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15473985 0,17324526 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15473985 0,17316468 ! cell fate determination GO:0001709 60 29 0,000 0,15473985 0,17308418 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15473985 0,17300375 ! detection of light stimulus GO:0009583 38 29 0,000 0,15473985 0,1729234 ! regulation of coagulation GO:0050818 46 29 0,000 0,15473985 0,17284312 ! zinc ion transport GO:0006829 45 30 0,000 0,15962802 0,17822042 ! membrane docking GO:0022406 61 30 0,000 0,15962802 0,17813776 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,15962802 0,17805517 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15962802 0,17797266 ! acute-phase response GO:0006953 49 30 0,000 0,15962802 0,17789023 ! myofibril assembly GO:0030239 47 30 0,000 0,15962802 0,17780787 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,15962802 0,17772559 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15962802 0,17764339 ! phospholipid transport GO:0015914 51 30 0,000 0,15962802 0,17756126 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15962802 0,17747921 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15962802 0,17739723 ! eye morphogenesis GO:0048592 60 30 0,000 0,15962802 0,17731533 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16448808 0,18262959 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16448808 0,18254535 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16448808 0,18246119 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16448808 0,18237711 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16448808 0,1822931 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16448808 0,18220917 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16448808 0,18212532 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16448808 0,18204155 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16448808 0,18195785 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16448808 0,18187423 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16448808 0,18179068 ! mesoderm formation GO:0001707 69 31 0,000 0,16448808 0,18170722 ! natural killer cell activation GO:0030101 45 31 0,000 0,16448808 0,18162383 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16448808 0,18154051 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16448808 0,18145728 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16448808 0,18137412 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,1693202 0,18661676 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1693202 0,18653132 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1693202 0,18644595 ! cholesterol transport GO:0030301 56 32 0,000 0,1693202 0,18636066 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1693202 0,18627544 ! spliceosome assembly GO:0000245 67 32 0,000 0,1693202 0,18619031 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,1693202 0,18610525 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,1693202 0,18602027 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,1693202 0,18593537 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,1693202 0,18585054 ! muscle cell development GO:0055001 49 32 0,000 0,1693202 0,1857658 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1693202 0,18568113 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1693202 0,18559653 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,1693202 0,18551202 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1693202 0,18542758 ! gene silencing GO:0016458 65 32 0,000 0,1693202 0,18534322 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,17412453 0,19051551 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,17412453 0,19042892 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17412453 0,1903424 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17412453 0,19025596 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17412453 0,19016959 ! cell fate specification GO:0001708 52 33 0,000 0,17412453 0,19008331 ! sterol transport GO:0015918 57 33 0,000 0,17412453 0,1899971 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17412453 0,18991098 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17412453 0,18982493 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,17412453 0,18973896 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17412453 0,18965306 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,17890123 0,19476758 ! glial cell differentiation GO:0010001 63 34 0,000 0,17890123 0,19467949 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,17890123 0,19459148 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,17890123 0,19450355 ! mismatch repair GO:0006298 46 34 0,000 0,17890123 0,1944157 ! spermatid development GO:0007286 63 34 0,000 0,17890123 0,19432793 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17890123 0,19424024 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18365046 0,19930673 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,18365046 0,19921687 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18365046 0,19912709 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18365046 0,19903739 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,18365046 0,19894778 ! neural tube formation GO:0001841 67 35 0,000 0,18365046 0,19885824 ! vesicle localization GO:0051648 64 35 0,000 0,18365046 0,19876879 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,18837238 0,20378775 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,18837238 0,20369616 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18837238 0,20360465 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18837238 0,20351323 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,18837238 0,20342188 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,18837238 0,20333062 ! regulation of proteolysis GO:0030162 72 36 0,000 0,18837238 0,20323944 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18837238 0,20314834 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18837238 0,20305733 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19306715 0,20802488 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19306715 0,20793176 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19306715 0,20783873 ! organic anion transport GO:0015711 68 37 0,000 0,19306715 0,20774578 ! tissue remodeling GO:0048771 76 37 0,000 0,19306715 0,20765291 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19306715 0,20756013 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19306715 0,20746742 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19306715 0,2073748 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19306715 0,20728227 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,19306715 0,20718981 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19773491 0,21210441 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19773491 0,21200989 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,19773491 0,21191546 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19773491 0,2118211 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,19773491 0,21172684 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,19773491 0,21163265 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,19773491 0,21153855 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,19773491 0,21144453 ! mRNA catabolic process GO:0006402 71 39 0,000 0,20237583 0,21631108 ! learning GO:0007612 77 39 0,000 0,20237583 0,21621503 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20237583 0,21611906 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20237583 0,21602318 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20237583 0,21592738 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,20237583 0,21583167 ! RNA modification GO:0009451 57 39 0,000 0,20237583 0,21573604 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20237583 0,2156405 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,20699005 0,22045952 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,20699005 0,22036198 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20699005 0,22026451 ! feeding behavior GO:0007631 59 40 0,000 0,20699005 0,22016714 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,20699005 0,22006985 ! maintenance of protein location GO:0045185 91 40 0,000 0,20699005 0,21997264 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21157773 0,2247488 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,21157773 0,22464962 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21157773 0,22455052 ! polyol metabolic process GO:0019751 66 41 0,000 0,21157773 0,22445151 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,21157773 0,22435259 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21613903 0,22908833 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,21613903 0,22898745 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,21613903 0,22888666 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21613903 0,22878597 ! regulation of protein secretion GO:0050708 71 42 0,000 0,21613903 0,22868536 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,21613903 0,22858484 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22067408 0,23327849 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22067408 0,23317604 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22067408 0,23307368 ! neural tube development GO:0021915 77 43 0,000 0,22067408 0,23297141 ! striated muscle contraction GO:0006941 77 43 0,000 0,22067408 0,23286923 ! phagocytosis GO:0006909 90 43 0,000 0,22067408 0,23276714 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22067408 0,23266514 ! double-strand break repair GO:0006302 81 44 0,000 0,22518305 0,23731512 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22518305 0,23721122 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,22518305 0,23710741 ! maintenance of location in cell GO:0051651 97 44 0,000 0,22518305 0,23700369 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22966608 0,24161635 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,22966608 0,24151075 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22966608 0,24140524 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22966608 0,24129982 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22966608 0,2411945 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22966608 0,24108926 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22966608 0,24098412 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,23855492 0,25020189 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,23855492 0,25009287 ! Notch signaling pathway GO:0007219 96 48 0,000 0,24296102 0,25460114 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,24296102 0,2544903 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24296102 0,25437955 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24734177 0,25885354 ! regulation of ion transport GO:0043269 77 49 0,000 0,24734177 0,258741 ! peptide metabolic process GO:0006518 76 49 0,000 0,24734177 0,25862855 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24734177 0,2585162 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,24734177 0,25840395 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24734177 0,2582918 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24734177 0,25817974 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,25169731 0,2626122 ! neuromuscular process GO:0050905 99 50 0,000 0,25169731 0,26249837 ! inner ear development GO:0048839 79 50 0,000 0,25169731 0,26238464 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,25169731 0,262271 ! viral infectious cycle GO:0019058 99 51 0,000 0,2560278 0,26666791 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,2560278 0,26655252 ! excretion GO:0007588 83 51 0,000 0,2560278 0,26643723 ! chromatin remodeling GO:0006338 109 51 0,000 0,2560278 0,26632204 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,2560278 0,26620695 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,2560278 0,26609196 ! regulation of cell shape GO:0008360 125 51 0,000 0,2560278 0,26597707 ! amino acid activation GO:0043038 92 52 0,000 0,26033336 0,27033322 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26461416 0,27465991 ! RNA catabolic process GO:0006401 93 53 0,000 0,26461416 0,27454147 ! regulation of translational initiation GO:0006446 82 53 0,000 0,26461416 0,27442313 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26461416 0,27430489 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,26461416 0,27418676 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,26461416 0,27406873 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,26461416 0,2739508 ! cell recognition GO:0008037 85 54 0,000 0,26887031 0,27823741 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,26887031 0,27811779 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,26887031 0,27799827 ! chloride transport GO:0006821 90 55 0,000 0,27310198 0,2822523 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27310198 0,28213111 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,27310198 0,28201003 ! gastrulation GO:0007369 112 55 0,000 0,27310198 0,28188905 ! regulation of actin filament length GO:0030832 105 56 0,000 0,27730929 0,28610899 ! sensory perception of smell GO:0007608 80 56 0,000 0,27730929 0,28598635 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27730929 0,28586382 ! proton transport GO:0015992 94 56 0,000 0,27730929 0,2857414 ! hydrogen transport GO:0006818 97 58 0,000 0,28565142 0,29421118 ! adult behavior GO:0030534 99 58 0,000 0,28565142 0,29408529 ! positive regulation of secretion GO:0051047 95 59 0,000 0,28978651 0,29821486 ! regulation of cellular component size GO:0032535 109 59 0,000 0,28978651 0,29808736 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28978651 0,29795998 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,28978651 0,2978327 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,2938978 0,30192917 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,2938978 0,3018003 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,2938978 0,30167155 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,29798543 0,30573686 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,29798543 0,30560654 ! mesoderm development GO:0007498 119 61 0,000 0,29798543 0,30547632 ! tRNA processing GO:0008033 89 61 0,000 0,29798543 0,30534622 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,29798543 0,30521623 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,30204952 0,3092473 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,30609023 0,313251 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,30609023 0,31311781 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,30609023 0,31298474 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31010767 0,31695797 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,31010767 0,31682338 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,31410199 0,32076799 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,31807332 0,32468579 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,32202178 0,32857693 ! adaptive immune response GO:0002250 119 67 0,000 0,32202178 0,32843764 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,32202178 0,32829848 ! amino acid transport GO:0006865 125 68 0,000 0,32594751 0,33215998 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,32594751 0,33201935 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,32594751 0,33187884 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,32985064 0,33571093 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,32985064 0,33556898 ! amine catabolic process GO:0009310 117 71 0,000 0,33758961 0,34329696 ! regulation of immune effector process GO:0002697 137 71 0,000 0,33758961 0,34315192 ! acute inflammatory response GO:0002526 113 72 0,000 0,34142571 0,34690467 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,34523972 0,35063181 ! transition metal ion transport GO:0000041 126 74 0,000 0,34903177 0,35433352 ! neurotransmitter transport GO:0006836 123 74 0,000 0,34903177 0,35418407 ! exocytosis GO:0006887 133 74 0,000 0,34903177 0,35403475 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,34903177 0,35388556 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,34903177 0,35373649 ! defense response to bacterium GO:0042742 89 76 0,000 0,35655048 0,3612044 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,35655048 0,36105238 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36027739 0,36467287 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,36027739 0,36451952 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,36766695 0,37183972 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,36766695 0,37168348 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,37132985 0,37522873 ! inorganic anion transport GO:0015698 138 80 0,000 0,37132985 0,3750712 ! digestion GO:0007586 112 81 0,000 0,37497164 0,37859075 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,37497164 0,37843195 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,38577165 0,38916838 ! response to unfolded protein GO:0006986 131 85 0,000 0,38933026 0,39259372 ! nucleosome assembly GO:0006334 122 85 0,000 0,38933026 0,39242925 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,39286837 0,39582969 ! chromatin assembly GO:0031497 124 86 0,000 0,39286837 0,395664 ! amine transport GO:0015837 155 86 0,000 0,39286837 0,39549845 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,3963861 0,39887284 ! regulation of neurological system process GO:0031644 148 88 0,000 0,39988356 0,40222402 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39988356 0,40205594 ! cellular defense response GO:0006968 114 89 0,000 0,40336088 0,40538274 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,40681816 0,40868663 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41025552 0,41196777 ! nucleosome organization GO:0034728 138 92 0,000 0,41367308 0,41522629 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,41367308 0,41505314 ! vitamin metabolic process GO:0006766 139 92 0,000 0,41367308 0,41488012 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,41707094 0,41811362 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,42714751 0,42803703 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,42714751 0,42785883 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,43046773 0,43100514 ! protein ubiquitination GO:0016567 217 97 0,000 0,43046773 0,43082586 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,43376882 0,43394918 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,43376882 0,43376882 GO:0016054|organic acid catabolic process,