pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6605-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of protein kinase activity GO:0045860 89 86 6,000 1,085E-08 2E-05 ! positive regulation of MAP kinase activity GO:0043406 50 49 5,000 1,162E-08 1,071E-05 ! heart development GO:0007507 90 87 6,000 1,177E-08 7,234E-06 ! positive regulation of transferase activity GO:0051347 91 88 6,000 1,276E-08 5,881E-06 GO:0033674|positive regulation of kinase activity, ! protein amino acid autophosphorylation GO:0046777 28 28 4,000 3,088E-08 1,138E-05 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 3,000 3,699E-08 1,136E-05 ! regulation of MAP kinase activity GO:0043405 67 66 5,000 7,269E-08 1,914E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 3,000 7,976E-08 1,838E-05 ! base-excision repair GO:0006284 14 14 3,000 1,114E-07 2,281E-05 ! ER-nuclear signaling pathway GO:0006984 15 15 3,000 1,516E-07 2,793E-05 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 2,000 3,714E-07 6,222E-05 GO:0009155|purine deoxyribonucleotide catabolic process, ! ER overload response GO:0006983 6 6 2,000 7,41E-07 1,138E-04 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 7,41E-07 1,051E-04 ! base-excision repair, AP site formation GO:0006285 8 8 2,000 2,065E-06 2,719E-04 ! striated muscle tissue development GO:0014706 69 67 4,000 2,773E-06 3,407E-04 ! muscle tissue development GO:0060537 72 70 4,000 3,451E-06 3,975E-04 ! regulation of cell migration GO:0030334 71 71 4,000 3,704E-06 4,016E-04 ! neuromuscular junction development GO:0007528 10 10 2,000 4,406E-06 4,511E-04 ! signal complex assembly GO:0007172 11 11 2,000 6,044E-06 5,862E-04 ! hindbrain development GO:0030902 11 11 2,000 6,044E-06 5,569E-04 ! positive regulation of cell migration GO:0030335 36 36 3,000 6,228E-06 5,466E-04 ! regulation of locomotion GO:0040012 79 79 4,000 6,294E-06 5,273E-04 ! regulation of cell motion GO:0051270 79 79 4,000 6,294E-06 5,044E-04 ! MAPKKK cascade GO:0000165 82 81 4,000 7,123E-06 5,47E-04 ! deoxyribonucleotide catabolic process GO:0009264 12 12 2,000 8,04E-06 5,927E-04 ! nucleotide-excision repair GO:0006289 40 39 3,000 8,636E-06 6,122E-04 ! positive regulation of cell motion GO:0051272 39 39 3,000 8,636E-06 5,895E-04 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 2,000 1,043E-05 6,864E-04 GO:0019692|deoxyribose phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 1,043E-05 6,627E-04 ! purine nucleotide catabolic process GO:0006195 13 13 2,000 1,043E-05 6,406E-04 ! protein tetramerization GO:0051262 13 13 2,000 1,043E-05 6,2E-04 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,324E-05 7,626E-04 ! D-ribose metabolic process GO:0006014 14 14 2,000 1,324E-05 7,395E-04 ! regulation of vasoconstriction GO:0019229 14 14 2,000 1,324E-05 7,178E-04 ! DNA modification GO:0006304 14 14 2,000 1,324E-05 6,973E-04 ! pattern specification process GO:0007389 96 94 4,000 1,481E-05 7,58E-04 ! deoxyribonucleotide metabolic process GO:0009262 15 15 2,000 1,651E-05 8,226E-04 ! muscle organ development GO:0007517 102 100 4,000 2,003E-05 9,714E-04 ! pentose metabolic process GO:0019321 16 16 2,000 2,028E-05 9,583E-04 ! regulation of JUN kinase activity GO:0043506 17 16 2,000 2,028E-05 9,343E-04 GO:0043507|positive regulation of JUN kinase activity, ! skeletal muscle tissue development GO:0007519 50 49 3,000 2,173E-05 9,77E-04 GO:0060538|skeletal muscle organ development, ! regulation of pH GO:0006885 19 19 2,000 3,485E-05 1,529E-03 ! dorsal/ventral pattern formation GO:0009953 19 19 2,000 3,485E-05 1,494E-03 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 4,561E-05 1,91E-03 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 3,000 5,205E-05 2,132E-03 ! monovalent inorganic cation homeostasis GO:0055067 23 23 2,000 6,311E-05 2,529E-03 ! calcium-mediated signaling GO:0019722 23 23 2,000 6,311E-05 2,475E-03 ! regulation of JNK cascade GO:0046328 25 23 2,000 6,311E-05 2,423E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 2,000 7,196E-05 2,707E-03 ! nucleotide catabolic process GO:0009166 24 24 2,000 7,196E-05 2,652E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 8,159E-05 2,948E-03 ! regionalization GO:0003002 70 69 3,000 8,464E-05 3E-03 ! synapse organization GO:0050808 26 26 2,000 9,202E-05 3,2E-03 ! positive regulation of hydrolase activity GO:0051345 72 72 3,000 1E-04 3,414E-03 ! mesenchymal cell development GO:0014031 29 27 2,000 1,033E-04 3,461E-03 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,159E-04 3,814E-03 ! middle ear morphogenesis GO:0042474 5 5 1,000 1,159E-04 3,747E-03 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 1,000 1,159E-04 3,682E-03 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! phasic smooth muscle contraction GO:0014821 5 5 1,000 1,159E-04 3,62E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,159E-04 3,56E-03 ! receptor clustering GO:0043113 5 5 1,000 1,159E-04 3,501E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,159E-04 3,445E-03 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 1,159E-04 3,39E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 1,159E-04 3,337E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,159E-04 3,286E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,159E-04 3,236E-03 ! positive regulation of smooth muscle contraction GO:0045987 5 5 1,000 1,159E-04 3,188E-03 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,284E-04 3,481E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,284E-04 3,43E-03 ! response to UV GO:0009411 29 29 2,000 1,284E-04 3,381E-03 ! regulation of protein modification process GO:0031399 79 78 3,000 1,367E-04 3,55E-03 ! activation of phospholipase C activity GO:0007202 30 30 2,000 1,424E-04 3,644E-03 GO:0010863|positive regulation of phospholipase C activity, ! neuron projection development GO:0031175 85 80 3,000 1,509E-04 3,81E-03 ! skeletal muscle fiber development GO:0048741 31 31 2,000 1,573E-04 3,917E-03 ! positive regulation of phospholipase activity GO:0010518 31 31 2,000 1,573E-04 3,865E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 1,573E-04 3,814E-03 ! muscle fiber development GO:0048747 32 32 2,000 1,731E-04 4,144E-03 ! regulation of phospholipase activity GO:0010517 32 32 2,000 1,731E-04 4,091E-03 ! positive regulation of lipase activity GO:0060193 32 32 2,000 1,731E-04 4,039E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,735E-04 3,996E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 1,735E-04 3,947E-03 ! positive regulation of heart contraction GO:0045823 6 6 1,000 1,735E-04 3,899E-03 ! inositol phosphate-mediated signaling GO:0048016 6 6 1,000 1,735E-04 3,852E-03 ! vascular smooth muscle contraction GO:0014829 6 6 1,000 1,735E-04 3,806E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,735E-04 3,761E-03 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 1,000 1,735E-04 3,717E-03 ! regulation of heart rate GO:0002027 6 6 1,000 1,735E-04 3,675E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 1,735E-04 3,633E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,735E-04 3,592E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,735E-04 3,552E-03 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 1,735E-04 3,513E-03 ! renal water homeostasis GO:0003091 6 6 1,000 1,735E-04 3,475E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,735E-04 3,438E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 1,735E-04 3,401E-03 ! localization within membrane GO:0051668 6 6 1,000 1,735E-04 3,365E-03 ! regulation of cellular response to stress GO:0080135 35 33 2,000 1,9E-04 3,648E-03 ! activation of protein kinase activity GO:0032147 35 33 2,000 1,9E-04 3,61E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 2,269E-04 4,267E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 2,423E-04 4,511E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 2,423E-04 4,466E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 1,000 2,423E-04 4,422E-03 ! response to X-ray GO:0010165 7 7 1,000 2,423E-04 4,379E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 2,423E-04 4,336E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 2,423E-04 4,294E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 1,000 2,423E-04 4,254E-03 ! cranial nerve development GO:0021545 7 7 1,000 2,423E-04 4,213E-03 ! autonomic nervous system development GO:0048483 7 7 1,000 2,423E-04 4,174E-03 ! response to gamma radiation GO:0010332 8 7 1,000 2,423E-04 4,135E-03 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 2,423E-04 4,097E-03 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 1,000 2,423E-04 4,06E-03 ! cAMP biosynthetic process GO:0006171 7 7 1,000 2,423E-04 4,024E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 2,423E-04 3,988E-03 ! heterocycle catabolic process GO:0046700 36 36 2,000 2,47E-04 4,028E-03 ! regulation of lipase activity GO:0060191 36 36 2,000 2,47E-04 3,993E-03 ! negative regulation of cell cycle GO:0045786 92 91 3,000 2,486E-04 3,984E-03 ! regulation of MAPKKK cascade GO:0043408 41 39 2,000 3,14E-04 4,988E-03 ! protein oligomerization GO:0051259 39 39 2,000 3,14E-04 4,945E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 3,224E-04 5,036E-03 ! sex determination GO:0007530 8 8 1,000 3,224E-04 4,993E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 3,224E-04 4,952E-03 ! vasoconstriction GO:0042310 8 8 1,000 3,224E-04 4,911E-03 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 3,224E-04 4,871E-03 ! peptidyl-serine modification GO:0018209 8 8 1,000 3,224E-04 4,831E-03 ! water homeostasis GO:0030104 8 8 1,000 3,224E-04 4,792E-03 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 1,000 3,224E-04 4,754E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 3,224E-04 4,716E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 3,224E-04 4,679E-03 ! peptide hormone secretion GO:0030072 8 8 1,000 3,224E-04 4,642E-03 ! blood circulation GO:0008015 99 98 3,000 3,305E-04 4,722E-03 GO:0003013|circulatory system process, ! DNA catabolic process GO:0006308 41 40 2,000 3,386E-04 4,801E-03 ! embryonic pattern specification GO:0009880 10 9 1,000 4,137E-04 5,82E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 4,137E-04 5,776E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 4,137E-04 5,732E-03 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 1,000 4,137E-04 5,689E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 4,137E-04 5,647E-03 ! peptide secretion GO:0002790 9 9 1,000 4,137E-04 5,606E-03 ! regulation of cellular pH GO:0030641 9 9 1,000 4,137E-04 5,565E-03 ! histone acetylation GO:0016573 9 9 1,000 4,137E-04 5,524E-03 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 4,808E-04 6,375E-03 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 4,808E-04 6,33E-03 ! regulation of membrane potential GO:0042391 46 46 2,000 5,132E-04 6,708E-03 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 5,16E-04 6,697E-03 ! hormone secretion GO:0046879 10 10 1,000 5,16E-04 6,65E-03 ! inositol metabolic process GO:0006020 10 10 1,000 5,16E-04 6,604E-03 ! cAMP metabolic process GO:0046058 10 10 1,000 5,16E-04 6,558E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 5,16E-04 6,513E-03 ! nerve development GO:0021675 10 10 1,000 5,16E-04 6,469E-03 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 5,16E-04 6,425E-03 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 5,16E-04 6,382E-03 ! negative regulation of coagulation GO:0050819 11 10 1,000 5,16E-04 6,34E-03 ! ossification GO:0001503 50 49 2,000 6,186E-04 7,55E-03 GO:0060348|bone development, ! positive regulation of hormone secretion GO:0046887 11 11 1,000 6,293E-04 7,63E-03 ! microtubule-based transport GO:0010970 11 11 1,000 6,293E-04 7,58E-03 ! endothelial cell migration GO:0043542 11 11 1,000 6,293E-04 7,531E-03 ! protein amino acid acetylation GO:0006473 11 11 1,000 6,293E-04 7,482E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 6,293E-04 7,434E-03 GO:0032388|positive regulation of intracellular transport, ! dendrite development GO:0016358 11 11 1,000 6,293E-04 7,387E-03 ! activation of MAPKK activity GO:0000186 12 11 1,000 6,293E-04 7,34E-03 ! smooth muscle contraction GO:0006939 11 11 1,000 6,293E-04 7,294E-03 ! cellular response to starvation GO:0009267 11 11 1,000 6,293E-04 7,249E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 6,293E-04 7,204E-03 ! body fluid secretion GO:0007589 11 11 1,000 6,293E-04 7,159E-03 ! G1/S transition checkpoint GO:0031575 12 11 1,000 6,293E-04 7,115E-03 ! interaction with host GO:0051701 11 11 1,000 6,293E-04 7,072E-03 ! membrane depolarization GO:0051899 11 11 1,000 6,293E-04 7,029E-03 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 6,293E-04 6,987E-03 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 6,293E-04 6,945E-03 GO:0006109|regulation of carbohydrate metabolic process, ! endocrine process GO:0050886 11 11 1,000 6,293E-04 6,903E-03 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 6,293E-04 6,863E-03 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 6,566E-04 7,118E-03 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 6,566E-04 7,076E-03 ! cell fate commitment GO:0045165 52 52 2,000 7,369E-04 7,896E-03 ! response to light stimulus GO:0009416 53 52 2,000 7,369E-04 7,851E-03 ! C21-steroid hormone metabolic process GO:0008207 13 12 1,000 7,535E-04 7,981E-03 ! regulation of muscle cell differentiation GO:0051147 13 12 1,000 7,535E-04 7,936E-03 ! osteoblast differentiation GO:0001649 12 12 1,000 7,535E-04 7,891E-03 ! renal system process GO:0003014 12 12 1,000 7,535E-04 7,846E-03 ! somitogenesis GO:0001756 13 12 1,000 7,535E-04 7,802E-03 ! hormone transport GO:0009914 12 12 1,000 7,535E-04 7,758E-03 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 7,535E-04 7,715E-03 ! response to hypoxia GO:0001666 53 53 2,000 7,794E-04 7,936E-03 ! response to oxygen levels GO:0070482 55 54 2,000 8,233E-04 8,337E-03 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 8,233E-04 8,292E-03 ! in utero embryonic development GO:0001701 55 55 2,000 8,688E-04 8,703E-03 ! regulation of cell adhesion GO:0030155 56 55 2,000 8,688E-04 8,655E-03 ! positive regulation of DNA replication GO:0045740 14 13 1,000 8,886E-04 8,805E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 8,886E-04 8,758E-03 ! negative regulation of hormone secretion GO:0046888 13 13 1,000 8,886E-04 8,712E-03 ! patterning of blood vessels GO:0001569 13 13 1,000 8,886E-04 8,666E-03 ! mitochondrial membrane organization GO:0007006 13 13 1,000 8,886E-04 8,62E-03 ! negative regulation of DNA replication GO:0008156 13 13 1,000 8,886E-04 8,575E-03 ! receptor metabolic process GO:0043112 14 13 1,000 8,886E-04 8,53E-03 ! cell aging GO:0007569 13 13 1,000 8,886E-04 8,486E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 8,886E-04 8,442E-03 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 8,886E-04 8,399E-03 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 8,886E-04 8,356E-03 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 1,000 8,886E-04 8,314E-03 ! neutrophil chemotaxis GO:0030593 14 13 1,000 8,886E-04 8,272E-03 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 8,886E-04 8,23E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 8,886E-04 8,189E-03 GO:0001952|regulation of cell-matrix adhesion, ! extracellular structure organization GO:0043062 56 56 2,000 9,159E-04 8,398E-03 ! protein amino acid acylation GO:0043543 14 14 1,000 1,035E-03 9,439E-03 ! peptide transport GO:0015833 14 14 1,000 1,035E-03 9,392E-03 ! formation of primary germ layer GO:0001704 14 14 1,000 1,035E-03 9,346E-03 GO:0001707|mesoderm formation, ! regulation of blood coagulation GO:0030193 15 14 1,000 1,035E-03 9,301E-03 ! positive regulation of osteoblast differentiation GO:0045669 14 14 1,000 1,035E-03 9,256E-03 ! regulation of cell development GO:0060284 60 59 2,000 1,067E-03 9,498E-03 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,191E-03 0,01055446 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 1,191E-03 0,01050396 ! regulation of smooth muscle contraction GO:0006940 15 15 1,000 1,191E-03 0,01045394 ! mesoderm morphogenesis GO:0048332 15 15 1,000 1,191E-03 0,0104044 ! response to starvation GO:0042594 15 15 1,000 1,191E-03 0,01035532 ! response to ionizing radiation GO:0010212 16 15 1,000 1,191E-03 0,0103067 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 1,000 1,191E-03 0,01025854 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,191E-03 0,01021083 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 1,233E-03 0,01051708 ! angiogenesis GO:0001525 65 64 2,000 1,352E-03 0,01148 ! positive regulation of mitosis GO:0045840 16 16 1,000 1,358E-03 0,01148444 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,358E-03 0,011432 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 1,358E-03 0,01138003 ! positive regulation of cytoskeleton organization GO:0051495 16 16 1,000 1,358E-03 0,01132854 ! segmentation GO:0035282 17 16 1,000 1,358E-03 0,01127751 ! regulation of systemic arterial blood pressure GO:0003073 17 16 1,000 1,358E-03 0,01122694 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,358E-03 0,01117682 ! polyol metabolic process GO:0019751 16 16 1,000 1,358E-03 0,01112714 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,358E-03 0,01107791 ! regulation of coagulation GO:0050818 17 16 1,000 1,358E-03 0,01102911 ! regulation of hormone levels GO:0010817 66 65 2,000 1,414E-03 0,01142866 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 1,536E-03 0,01236413 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 1,536E-03 0,01231037 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,536E-03 0,01225708 ! myelination GO:0042552 17 17 1,000 1,536E-03 0,01220424 ! glucose transport GO:0015758 17 17 1,000 1,536E-03 0,01215187 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 1,536E-03 0,01209993 ! neural crest cell development GO:0014032 19 17 1,000 1,536E-03 0,01204845 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 18 17 1,000 1,536E-03 0,01199739 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,536E-03 0,01194677 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 1,536E-03 0,01189657 ! response to radiation GO:0009314 70 68 2,000 1,611E-03 0,01242357 ! regulation of cell size GO:0008361 68 68 2,000 1,611E-03 0,0123718 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 1,68E-03 0,01285107 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 1,725E-03 0,01313443 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 1,725E-03 0,01308038 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 1,725E-03 0,01302677 ! hexose transport GO:0008645 18 18 1,000 1,725E-03 0,0129736 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 1,725E-03 0,01292086 ! B cell differentiation GO:0030183 18 18 1,000 1,725E-03 0,01286855 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 1,725E-03 0,01281666 ! ensheathment of neurons GO:0007272 18 18 1,000 1,725E-03 0,01276519 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 1,000 1,725E-03 0,01271413 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 1,725E-03 0,01266347 ! positive regulation of transport GO:0051050 71 70 2,000 1,752E-03 0,01281109 ! DNA damage checkpoint GO:0000077 19 19 1,000 1,923E-03 0,01401154 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 1,923E-03 0,01395638 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 1,923E-03 0,01390165 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 1,923E-03 0,01384735 ! cellular response to oxidative stress GO:0034599 19 19 1,000 1,923E-03 0,01379347 ! peripheral nervous system development GO:0007422 19 19 1,000 1,923E-03 0,01374 ! regulation of protein stability GO:0031647 19 19 1,000 1,923E-03 0,01368695 ! hormone biosynthetic process GO:0042446 19 19 1,000 1,923E-03 0,01363431 ! regulation of muscle development GO:0048634 21 20 1,000 2,133E-03 0,0150591 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 2,133E-03 0,01500162 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 2,133E-03 0,01494458 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,133E-03 0,01488797 ! cyclic nucleotide metabolic process GO:0009187 20 20 1,000 2,133E-03 0,01483179 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 2,133E-03 0,01477603 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 2,304E-03 0,01590137 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,352E-03 0,01617506 ! mammary gland development GO:0030879 23 21 1,000 2,352E-03 0,01611493 ! ear morphogenesis GO:0042471 21 21 1,000 2,352E-03 0,01605525 ! DNA integrity checkpoint GO:0031570 21 21 1,000 2,352E-03 0,015996 ! regulation of action potential in neuron GO:0019228 21 21 1,000 2,352E-03 0,01593719 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 2,352E-03 0,01587882 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 2,352E-03 0,01582086 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 2,582E-03 0,0173028 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 2,582E-03 0,01724011 ! embryonic skeletal system development GO:0048706 22 22 1,000 2,582E-03 0,01717787 ! cell chemotaxis GO:0060326 23 22 1,000 2,582E-03 0,01711608 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 1,000 2,582E-03 0,01705474 ! tube development GO:0035295 83 81 2,000 2,662E-03 0,01752483 ! regulation of hormone secretion GO:0046883 23 23 1,000 2,822E-03 0,01850663 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 1,000 2,822E-03 0,018441 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 2,822E-03 0,01837584 ! positive regulation of growth GO:0045927 23 23 1,000 2,822E-03 0,01831114 ! blood vessel morphogenesis GO:0048514 84 83 2,000 2,854E-03 0,01845683 ! regulation of cellular localization GO:0060341 86 85 2,000 3,054E-03 0,01968115 ! mitochondrial transport GO:0006839 24 24 1,000 3,072E-03 0,01972497 ! regulation of action potential GO:0001508 24 24 1,000 3,072E-03 0,01965648 ! glucose homeostasis GO:0042593 24 24 1,000 3,072E-03 0,01958846 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 3,072E-03 0,01952092 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 3,072E-03 0,01945384 ! glucan metabolic process GO:0044042 25 24 1,000 3,072E-03 0,01938721 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 3,157E-03 0,01985989 ! negative regulation of secretion GO:0051048 26 25 1,000 3,332E-03 0,02088523 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 3,332E-03 0,02081443 ! regulation of T cell proliferation GO:0042129 25 25 1,000 3,332E-03 0,02074411 ! excretion GO:0007588 25 25 1,000 3,332E-03 0,02067427 ! positive regulation of DNA binding GO:0043388 26 25 1,000 3,332E-03 0,02060489 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 3,332E-03 0,02053598 ! gastrulation GO:0007369 25 25 1,000 3,332E-03 0,02046753 ! heart morphogenesis GO:0003007 25 25 1,000 3,332E-03 0,02039953 ! negative regulation of immune system process GO:0002683 25 25 1,000 3,332E-03 0,02033198 ! brain development GO:0007420 91 90 2,000 3,591E-03 0,02184498 ! positive regulation of binding GO:0051099 27 26 1,000 3,602E-03 0,02183491 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 3,602E-03 0,02176332 ! negative regulation of cell migration GO:0030336 26 26 1,000 3,602E-03 0,0216922 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 3,602E-03 0,02162154 ! regulation of T cell differentiation GO:0045580 26 26 1,000 3,602E-03 0,02155134 ! double-strand break repair GO:0006302 27 26 1,000 3,602E-03 0,0214816 ! regulation of blood vessel size GO:0050880 27 26 1,000 3,602E-03 0,0214123 GO:0035150|regulation of tube size, ! response to insulin stimulus GO:0032868 28 26 1,000 3,602E-03 0,02134345 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 3,882E-03 0,02292824 ! energy reserve metabolic process GO:0006112 28 27 1,000 3,882E-03 0,02285499 ! activation of caspase activity GO:0006919 27 27 1,000 3,882E-03 0,0227822 ! tissue morphogenesis GO:0048729 94 93 2,000 3,94E-03 0,02305179 ! regulation of response to stress GO:0080134 97 94 2,000 4,061E-03 0,02368224 ! blood vessel development GO:0001568 95 94 2,000 4,061E-03 0,02360753 ! carbohydrate transport GO:0008643 28 28 1,000 4,171E-03 0,02417461 ! regulation of muscle contraction GO:0006937 28 28 1,000 4,171E-03 0,02409883 ! histone modification GO:0016570 28 28 1,000 4,171E-03 0,02402352 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 4,171E-03 0,02394868 ! cartilage development GO:0051216 29 28 1,000 4,171E-03 0,02387431 ! vasculature development GO:0001944 97 96 2,000 4,308E-03 0,02458372 ! viral reproductive process GO:0022415 29 29 1,000 4,471E-03 0,02543037 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 4,471E-03 0,02535212 ! leukocyte migration GO:0050900 30 29 1,000 4,471E-03 0,02527436 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 4,471E-03 0,02519706 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 4,471E-03 0,02512024 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 4,471E-03 0,02504389 ! positive regulation of protein transport GO:0051222 29 29 1,000 4,471E-03 0,024968 ! regulation of system process GO:0044057 98 98 2,000 4,565E-03 0,02542056 ! response to reactive oxygen species GO:0000302 31 30 1,000 4,78E-03 0,02653382 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 4,78E-03 0,02645414 GO:0043280|positive regulation of caspase activity, ! skeletal system morphogenesis GO:0048705 31 30 1,000 4,78E-03 0,02637494 ! regulation of ossification GO:0030278 30 30 1,000 4,78E-03 0,0262962 ! vascular process in circulatory system GO:0003018 31 30 1,000 4,78E-03 0,02621794 ! B cell activation GO:0042113 31 31 1,000 5,099E-03 0,0278836 ! aging GO:0007568 32 31 1,000 5,099E-03 0,0278011 ! regulation of heart contraction GO:0008016 31 31 1,000 5,099E-03 0,02771909 ! regulation of intracellular transport GO:0032386 31 31 1,000 5,099E-03 0,02763756 ! negative regulation of cell motion GO:0051271 31 31 1,000 5,099E-03 0,02755652 ! negative regulation of cell growth GO:0030308 32 32 1,000 5,427E-03 0,02924547 ! lipid modification GO:0030258 32 32 1,000 5,427E-03 0,0291602 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 5,427E-03 0,02907544 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 5,427E-03 0,02899116 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 5,427E-03 0,02890737 ! negative regulation of cell size GO:0045792 33 33 1,000 5,765E-03 0,03061857 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 5,765E-03 0,03053058 ! regulation of synaptic transmission GO:0050804 33 33 1,000 5,765E-03 0,0304431 ! regulation of angiogenesis GO:0045765 35 34 1,000 6,112E-03 0,03218495 ! regulation of bone remodeling GO:0046850 34 34 1,000 6,112E-03 0,03209325 ! ear development GO:0043583 34 34 1,000 6,112E-03 0,03200208 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 6,112E-03 0,03191142 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 6,112E-03 0,03182128 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 6,112E-03 0,03173164 ! viral reproduction GO:0016032 34 34 1,000 6,112E-03 0,0316425 ! mesoderm development GO:0007498 35 35 1,000 6,469E-03 0,03339523 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 6,469E-03 0,03330195 ! regulation of tissue remodeling GO:0034103 35 35 1,000 6,469E-03 0,03320919 ! regulation of mitosis GO:0007088 37 36 1,000 6,835E-03 0,03499062 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 6,835E-03 0,03489369 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 6,835E-03 0,0347973 ! positive regulation of organelle organization GO:0010638 36 36 1,000 6,835E-03 0,03470144 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 6,835E-03 0,03460611 ! regulation of transcription factor activity GO:0051090 38 37 1,000 7,21E-03 0,036406 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 1,000 7,21E-03 0,03630653 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 7,21E-03 0,0362076 ! response to drug GO:0042493 37 37 1,000 7,21E-03 0,03610921 ! lung development GO:0030324 38 37 1,000 7,21E-03 0,03601136 ! negative regulation of growth GO:0045926 37 37 1,000 7,21E-03 0,03591403 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 7,21E-03 0,03581722 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 7,21E-03 0,03572094 ! positive regulation of secretion GO:0051047 39 38 1,000 7,595E-03 0,03752462 ! cellular hormone metabolic process GO:0034754 39 38 1,000 7,595E-03 0,03742429 ! negative regulation of kinase activity GO:0033673 38 38 1,000 7,595E-03 0,03732449 ! cell-matrix adhesion GO:0007160 39 38 1,000 7,595E-03 0,03722522 ! meiotic cell cycle GO:0051321 38 38 1,000 7,595E-03 0,03712648 ! axon guidance GO:0007411 39 38 1,000 7,595E-03 0,03702826 ! regulation of neurological system process GO:0031644 38 38 1,000 7,595E-03 0,03693056 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 7,595E-03 0,03683338 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 7,988E-03 0,03864038 ! activation of MAPK activity GO:0000187 39 39 1,000 7,988E-03 0,03853923 ! respiratory system development GO:0060541 40 39 1,000 7,988E-03 0,0384386 ! lymphocyte differentiation GO:0030098 39 39 1,000 7,988E-03 0,0383385 ! respiratory tube development GO:0030323 40 39 1,000 7,988E-03 0,03823892 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 7,988E-03 0,03813986 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 8,391E-03 0,0399586 ! negative regulation of transferase activity GO:0051348 40 40 1,000 8,391E-03 0,03985561 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 8,391E-03 0,03975316 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 8,802E-03 0,04159628 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 1,000 8,802E-03 0,0414899 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 1,000 8,802E-03 0,04138406 ! regulation of caspase activity GO:0043281 41 41 1,000 8,802E-03 0,04127875 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 9,223E-03 0,04314108 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 9,223E-03 0,04303186 ! cytosolic calcium ion homeostasis GO:0051480 42 42 1,000 9,223E-03 0,0429232 ! cell-substrate adhesion GO:0031589 43 42 1,000 9,223E-03 0,04281508 ! mitochondrion organization GO:0007005 44 43 1,000 9,652E-03 0,0446959 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 9,652E-03 0,04458388 ! protein import into nucleus GO:0006606 44 44 1,000 0,01009039 0,04649147 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,01053735 0,04842975 ! regulation of DNA binding GO:0051101 47 45 1,000 0,01053735 0,04830928 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,01053735 0,04818941 ! nuclear import GO:0051170 45 45 1,000 0,01053735 0,04807013 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,01099299 0,05002489 ! tube morphogenesis GO:0035239 47 46 1,000 0,01099299 0,04990168 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,01099299 0,04977907 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,01099299 0,04965706 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,01145726 0,0516277 ! regulation of blood pressure GO:0008217 48 47 1,000 0,01145726 0,05150178 ! regulation of catabolic process GO:0009894 48 47 1,000 0,01145726 0,05137647 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,0119301 0,05336691 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,0119301 0,05323769 ! protein localization in nucleus GO:0034504 48 48 1,000 0,0119301 0,0531091 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01241144 0,05511874 ! gland development GO:0048732 51 49 1,000 0,01241144 0,05498624 ! cell cycle arrest GO:0007050 49 49 1,000 0,01241144 0,05485438 ! negative regulation of transport GO:0051051 51 50 1,000 0,01290122 0,05688266 ! T cell activation GO:0042110 51 50 1,000 0,01290122 0,0567469 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01290122 0,05661179 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,01339939 0,05865816 GO:0051325|interphase, ! regulation of body fluid levels GO:0050878 55 52 1,000 0,01390589 0,06073118 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01442066 0,06283043 ! regulation of protein transport GO:0051223 53 53 1,000 0,01442066 0,06268225 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,01494363 0,06480262 ! hormone metabolic process GO:0042445 55 54 1,000 0,01494363 0,0646505 ! reproductive developmental process GO:0003006 56 56 1,000 0,01601397 0,06911886 ! regulation of nervous system development GO:0051960 57 56 1,000 0,01601397 0,06895737 ! regulation of binding GO:0051098 60 57 1,000 0,01656122 0,07114763 ! regulation of protein localization GO:0032880 58 57 1,000 0,01656122 0,07098217 ! rRNA transcription GO:0009303 5 5 0,000 0,0173256 0,07408603 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,0173256 0,07391453 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,0173256 0,07374383 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,0173256 0,07357391 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,0173256 0,07340478 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,0173256 0,07323642 ! reproductive cellular process GO:0048610 5 5 0,000 0,0173256 0,07306883 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,0173256 0,07290201 ! prostate gland development GO:0030850 5 5 0,000 0,0173256 0,07273594 ! metencephalon development GO:0022037 5 5 0,000 0,0173256 0,07257063 ! water transport GO:0006833 5 5 0,000 0,0173256 0,07240607 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,0173256 0,07224226 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,0173256 0,07207918 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,0173256 0,07191684 ! glycerol metabolic process GO:0006071 5 5 0,000 0,0173256 0,07175523 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,0173256 0,07159435 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,0173256 0,07143418 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,0173256 0,07127473 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,0173256 0,07111599 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,0173256 0,07095795 ! filopodium assembly GO:0046847 7 5 0,000 0,0173256 0,07080062 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,0173256 0,07064398 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,0173256 0,07048803 ! GTP metabolic process GO:0046039 5 5 0,000 0,0173256 0,07033277 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,0173256 0,0701782 ! mRNA stabilization GO:0048255 5 5 0,000 0,0173256 0,0700243 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,0173256 0,06987107 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,0173256 0,06971851 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,0173256 0,06956662 ! social behavior GO:0035176 5 5 0,000 0,0173256 0,06941539 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,0173256 0,06926481 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,0173256 0,06911489 ! memory GO:0007613 5 5 0,000 0,0173256 0,06896561 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,0173256 0,06881698 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,0173256 0,06866899 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,0173256 0,06852163 ! response to lipid GO:0033993 5 5 0,000 0,0173256 0,0683749 ! erythrocyte maturation GO:0043249 5 5 0,000 0,0173256 0,0682288 ! hippocampus development GO:0021766 6 5 0,000 0,0173256 0,06808332 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,0173256 0,06793847 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,0173256 0,06779422 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,0173256 0,06765059 ! mechanosensory behavior GO:0007638 5 5 0,000 0,0173256 0,06750757 ! heart looping GO:0001947 5 5 0,000 0,0173256 0,06736515 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,0173256 0,06722332 ! response to interferon-gamma GO:0034341 5 5 0,000 0,0173256 0,0670821 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,0173256 0,06694147 ! endocrine pancreas development GO:0031018 5 5 0,000 0,0173256 0,06680142 ! pH reduction GO:0045851 5 5 0,000 0,0173256 0,06666196 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,0173256 0,06652308 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,0173256 0,06638478 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,0173256 0,06624705 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,0173256 0,06610989 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,0173256 0,0659733 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,0173256 0,06583728 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,0173256 0,06570181 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,0173256 0,0655669 ! adrenal gland development GO:0030325 5 5 0,000 0,0173256 0,06543254 ! melanocyte differentiation GO:0030318 5 5 0,000 0,0173256 0,06529873 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,0173256 0,06516547 ! astrocyte differentiation GO:0048708 5 5 0,000 0,0173256 0,06503275 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,0173256 0,06490057 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,0173256 0,06476892 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,0173256 0,06463781 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,0173256 0,06450723 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,0173256 0,06437718 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,0173256 0,06424764 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,0173256 0,06411863 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,0173256 0,06399014 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,0173256 0,06386216 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,0173256 0,06373469 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,0173256 0,06360773 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,0173256 0,06348127 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,0173256 0,06335532 ! response to ATP GO:0033198 5 5 0,000 0,0173256 0,06322986 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,0173256 0,0631049 ! regulation of appetite GO:0032098 5 5 0,000 0,0173256 0,06298043 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,0173256 0,06285645 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,0173256 0,06273296 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,0173256 0,06260996 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,0173256 0,06248743 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0173256 0,06236539 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,0173256 0,06224382 ! fear response GO:0042596 5 5 0,000 0,0173256 0,06212272 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,0173256 0,06200209 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,0173256 0,06188194 ! retinol metabolic process GO:0042572 5 5 0,000 0,0173256 0,06176224 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,0173256 0,06164301 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,0173256 0,06152424 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,0173256 0,06140592 ! parturition GO:0007567 5 5 0,000 0,0173256 0,06128806 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0173256 0,06117065 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,0173256 0,06105369 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,0173256 0,06093717 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,0173256 0,0608211 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,0173256 0,06070547 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,0173256 0,06059028 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,0173256 0,06047553 ! response to UV-B GO:0010224 5 5 0,000 0,0173256 0,06036121 ! oligodendrocyte development GO:0014003 5 5 0,000 0,0173256 0,06024732 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,0173256 0,06013386 ! activated T cell proliferation GO:0050798 5 5 0,000 0,0173256 0,06002082 ! interaction with symbiont GO:0051702 5 5 0,000 0,0173256 0,05990822 ! cellular extravasation GO:0045123 5 5 0,000 0,0173256 0,05979603 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,0173256 0,05968426 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,0173256 0,05957291 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,0173256 0,05946197 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,0173256 0,05935145 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,0173256 0,05924133 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,0173256 0,05913163 ! response to amine stimulus GO:0014075 5 5 0,000 0,0173256 0,05902233 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,0173256 0,05891343 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,0173256 0,05880493 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,0173256 0,05869684 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,0173256 0,05858914 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,0173256 0,05848183 ! neuron recognition GO:0008038 5 5 0,000 0,0173256 0,05837492 ! decidualization GO:0046697 5 5 0,000 0,0173256 0,05826839 ! hair follicle maturation GO:0048820 5 5 0,000 0,0173256 0,05816226 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,0173256 0,05805651 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,0173256 0,05795114 ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,0173256 0,05784616 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,0173256 0,05774155 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,0173256 0,05763733 ! postreplication repair GO:0006301 5 5 0,000 0,0173256 0,05753348 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,0173256 0,05743 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,0173256 0,05732689 ! histone methylation GO:0016571 5 5 0,000 0,0173256 0,05722416 ! DNA methylation GO:0006306 5 5 0,000 0,0173256 0,05712179 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0173256 0,05701978 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,0173256 0,05691814 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,0173256 0,05681687 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,0173256 0,05671595 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,0173256 0,05661539 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,0173256 0,05651518 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,0173256 0,05641533 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,0173256 0,05631584 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,0173256 0,05621669 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,0173256 0,05611789 ! sterol catabolic process GO:0016127 5 5 0,000 0,0173256 0,05601944 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,0173256 0,05592133 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,0173256 0,05582356 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,0173256 0,05572614 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,0173256 0,05562906 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,0173256 0,05553231 ! zymogen activation GO:0031638 5 5 0,000 0,0173256 0,0554359 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,0173256 0,05533982 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,0173256 0,05524408 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,0173256 0,05514867 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,0173256 0,05505358 ! nucleosome positioning GO:0016584 5 5 0,000 0,0173256 0,05495883 ! regulation of isotype switching GO:0045191 5 5 0,000 0,0173256 0,0548644 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,0173256 0,05477029 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,0173256 0,0546765 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,0173256 0,05458304 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,0173256 0,0544899 ! NADPH regeneration GO:0006740 5 5 0,000 0,0173256 0,05439707 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,0173256 0,05430456 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,0173256 0,05421236 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,0173256 0,05412047 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,0173256 0,0540289 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,0173256 0,05393763 ! sarcomere organization GO:0045214 5 5 0,000 0,0173256 0,05384668 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,0173256 0,05375602 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,0173256 0,05366568 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,0173256 0,05357564 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,0173256 0,05348589 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,0173256 0,05339645 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,0173256 0,05330731 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,0173256 0,05321846 ! spleen development GO:0048536 5 5 0,000 0,0173256 0,05312991 ! male genitalia development GO:0030539 5 5 0,000 0,0173256 0,05304166 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,0173256 0,0529537 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,0173256 0,05286602 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,0173256 0,05277864 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,0173256 0,05269155 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,0173256 0,05260474 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,0173256 0,05251822 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,0173256 0,05243198 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,0173256 0,05234603 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,0173256 0,05226036 ! ATP catabolic process GO:0006200 5 5 0,000 0,0173256 0,05217497 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0173256 0,05208985 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,0173256 0,05200501 ! blastocyst formation GO:0001825 5 5 0,000 0,0173256 0,05192045 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,0173256 0,05183617 ! embryonic gut development GO:0048566 5 5 0,000 0,0173256 0,05175215 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,0173256 0,05166841 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,0173256 0,05158494 ! activation of innate immune response GO:0002218 5 5 0,000 0,0173256 0,05150174 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,0173256 0,05141881 ! catecholamine transport GO:0051937 5 5 0,000 0,0173256 0,05133614 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,0173256 0,05125374 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,0173256 0,0511716 ! muscle adaptation GO:0043500 5 5 0,000 0,0173256 0,05108973 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,0173256 0,05100811 ! embryonic heart tube development GO:0035050 5 5 0,000 0,0173256 0,05092676 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,0173256 0,05084567 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,0173256 0,05076483 ! defense response to fungus GO:0050832 5 5 0,000 0,0173256 0,05068425 ! lysogeny GO:0030069 5 5 0,000 0,0173256 0,05060393 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,0173256 0,05052386 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,0173256 0,05044404 ! response to nicotine GO:0035094 5 5 0,000 0,0173256 0,05036448 ! establishment of cell polarity GO:0030010 5 5 0,000 0,0173256 0,05028516 ! mitochondrion localization GO:0051646 5 5 0,000 0,0173256 0,0502061 ! nucleus localization GO:0051647 5 5 0,000 0,0173256 0,05012728 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,0173256 0,05004871 ! dephosphorylation GO:0016311 60 59 1,000 0,0176796 0,05099138 ! protein localization in organelle GO:0033365 59 59 1,000 0,0176796 0,05091171 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,01941597 0,05582471 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,01941597 0,05573776 ! protein import GO:0017038 62 62 1,000 0,01941597 0,05565107 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,01941597 0,05556466 ! regulation of secretion GO:0051046 65 63 1,000 0,02001023 0,05717651 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,02001023 0,057088 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,02061212 0,05871426 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,02061212 0,05862366 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,02061212 0,05853333 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02075603 0,05885132 ! axon extension GO:0048675 7 6 0,000 0,02075603 0,05876092 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02075603 0,05867079 ! tRNA modification GO:0006400 6 6 0,000 0,02075603 0,05858094 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02075603 0,05849137 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02075603 0,05840207 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02075603 0,05831304 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02075603 0,05822429 ! regulation of S phase GO:0033261 6 6 0,000 0,02075603 0,0581358 ! myotube differentiation GO:0014902 6 6 0,000 0,02075603 0,05804758 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02075603 0,05795963 ! bone remodeling GO:0046849 6 6 0,000 0,02075603 0,05787195 ! N-glycan processing GO:0006491 6 6 0,000 0,02075603 0,05778453 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02075603 0,05769737 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02075603 0,05761048 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02075603 0,05752384 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02075603 0,05743747 ! RNA methylation GO:0001510 6 6 0,000 0,02075603 0,05735136 ! cartilage condensation GO:0001502 7 6 0,000 0,02075603 0,0572655 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02075603 0,0571799 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02075603 0,05709456 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02075603 0,05700947 ! artery development GO:0060840 6 6 0,000 0,02075603 0,05692464 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02075603 0,05684005 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02075603 0,05675572 ! androgen metabolic process GO:0008209 6 6 0,000 0,02075603 0,05667164 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02075603 0,0565878 ! limbic system development GO:0021761 7 6 0,000 0,02075603 0,05650422 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02075603 0,05642088 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02075603 0,05633778 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02075603 0,05625493 ! pathogenesis GO:0009405 6 6 0,000 0,02075603 0,05617233 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02075603 0,05608996 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02075603 0,05600784 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02075603 0,05592596 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02075603 0,05584431 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02075603 0,05576291 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02075603 0,05568174 ! arginine metabolic process GO:0006525 6 6 0,000 0,02075603 0,05560081 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02075603 0,05552011 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02075603 0,05543965 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02075603 0,05535942 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02075603 0,05527942 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02075603 0,05519965 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02075603 0,05512011 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02075603 0,0550408 ! V(D)J recombination GO:0033151 6 6 0,000 0,02075603 0,05496172 ! focal adhesion formation GO:0048041 7 6 0,000 0,02075603 0,05488286 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02075603 0,05480423 ! lipid digestion GO:0044241 6 6 0,000 0,02075603 0,05472583 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02075603 0,05464765 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02075603 0,05456969 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02075603 0,05449196 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02075603 0,05441445 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02075603 0,05433715 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02075603 0,05426008 ! ruffle organization GO:0031529 6 6 0,000 0,02075603 0,05418322 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02075603 0,05410659 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02075603 0,05403016 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02075603 0,05395396 ! L-amino acid transport GO:0015807 6 6 0,000 0,02075603 0,05387797 ! bone mineralization GO:0030282 6 6 0,000 0,02075603 0,05380219 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02075603 0,05372662 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02075603 0,05365127 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02075603 0,05357613 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02075603 0,0535012 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02075603 0,05342647 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02075603 0,05335196 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02075603 0,05327765 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02075603 0,05320355 ! regulation of organ growth GO:0046620 6 6 0,000 0,02075603 0,05312966 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02075603 0,05305597 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02075603 0,05298249 ! response to dsRNA GO:0043331 6 6 0,000 0,02075603 0,05290921 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02075603 0,05283613 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02075603 0,05276325 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02075603 0,05269057 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02075603 0,0526181 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02075603 0,05254582 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02075603 0,05247374 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02075603 0,05240186 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02075603 0,05233017 ! erythrocyte development GO:0048821 6 6 0,000 0,02075603 0,05225868 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02075603 0,05218739 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02075603 0,05211629 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02075603 0,05204538 ! ribosome assembly GO:0042255 6 6 0,000 0,02075603 0,05197467 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02075603 0,05190415 ! diencephalon development GO:0021536 6 6 0,000 0,02075603 0,05183382 ! fucose catabolic process GO:0019317 6 6 0,000 0,02075603 0,05176367 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02075603 0,05169372 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02075603 0,05162396 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02075603 0,05155439 ! regulation of cell division GO:0051302 6 6 0,000 0,02075603 0,051485 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02075603 0,0514158 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02075603 0,05134679 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02075603 0,05127796 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02075603 0,05120931 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02075603 0,05114085 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02075603 0,05107257 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02075603 0,05100447 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02075603 0,05093656 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02075603 0,05086882 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02075603 0,05080127 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02075603 0,05073389 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02075603 0,0506667 ! thymus development GO:0048538 6 6 0,000 0,02075603 0,05059968 ! lymph node development GO:0048535 6 6 0,000 0,02075603 0,05053283 ! organic cation transport GO:0015695 6 6 0,000 0,02075603 0,05046617 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02075603 0,05039968 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02075603 0,05033336 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02075603 0,05026722 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02075603 0,05020125 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02075603 0,05013546 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02075603 0,05006984 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02075603 0,05000439 ! alditol metabolic process GO:0019400 6 6 0,000 0,02075603 0,04993911 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02075603 0,049874 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02075603 0,04980906 ! maternal placenta development GO:0001893 6 6 0,000 0,02075603 0,04974429 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02075603 0,04967968 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,02122158 0,05072812 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,02183858 0,05213536 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,02246304 0,05355677 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! muscle contraction GO:0006936 67 67 1,000 0,02246304 0,05348757 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,02246304 0,05341856 ! response to nutrient levels GO:0031667 69 69 1,000 0,02373415 0,05636862 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02373415 0,05629607 ! respiratory burst GO:0045730 7 7 0,000 0,02417497 0,05726797 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02417497 0,05719445 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02417497 0,05712113 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02417497 0,05704799 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02417497 0,05697504 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02417497 0,05690227 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02417497 0,05682969 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02417497 0,0567573 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02417497 0,05668509 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02417497 0,05661306 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02417497 0,05654122 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02417497 0,05646955 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02417497 0,05639807 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02417497 0,05632677 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02417497 0,05625566 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02417497 0,05618471 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02417497 0,05611395 ! axis specification GO:0009798 7 7 0,000 0,02417497 0,05604337 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02417497 0,05597296 ! visual behavior GO:0007632 7 7 0,000 0,02417497 0,05590273 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02417497 0,05583268 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02417497 0,0557628 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02417497 0,0556931 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02417497 0,05562357 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02417497 0,05555421 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02417497 0,05548503 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02417497 0,05541602 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02417497 0,05534718 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02417497 0,05527851 ! digestive system development GO:0055123 7 7 0,000 0,02417497 0,05521001 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02417497 0,05514168 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02417497 0,05507352 ! protein targeting to ER GO:0045047 8 7 0,000 0,02417497 0,05500553 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02417497 0,05493771 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02417497 0,05487005 ! endoderm development GO:0007492 7 7 0,000 0,02417497 0,05480256 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02417497 0,05473523 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02417497 0,05466807 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02417497 0,05460108 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02417497 0,05453425 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02417497 0,05446758 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02417497 0,05440107 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02417497 0,05433473 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02417497 0,05426855 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02417497 0,05420253 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02417497 0,05413667 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02417497 0,05407097 ! UV protection GO:0009650 7 7 0,000 0,02417497 0,05400543 ! DNA integration GO:0015074 7 7 0,000 0,02417497 0,05394005 ! myofibril assembly GO:0030239 7 7 0,000 0,02417497 0,05387482 GO:0055002|striated muscle cell development, ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02417497 0,05380976 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02417497 0,05374485 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02417497 0,05368009 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02417497 0,0536155 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02417497 0,05355106 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02417497 0,05348677 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02417497 0,05342264 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02417497 0,05335866 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02417497 0,05329483 ! axon cargo transport GO:0008088 7 7 0,000 0,02417497 0,05323116 ! eating behavior GO:0042755 7 7 0,000 0,02417497 0,05316764 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02417497 0,05310427 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02417497 0,05304105 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02417497 0,05297798 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02417497 0,05291506 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02417497 0,05285229 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02417497 0,05278967 ! induction of an organ GO:0001759 7 7 0,000 0,02417497 0,05272719 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02417497 0,05266487 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02417497 0,05260269 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02417497 0,05254066 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02417497 0,05247877 ! platelet activation GO:0030168 8 7 0,000 0,02417497 0,05241703 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02417497 0,05235544 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02417497 0,05229399 ! natural killer cell activation GO:0030101 7 7 0,000 0,02417497 0,05223268 ! NADP metabolic process GO:0006739 7 7 0,000 0,02417497 0,05217152 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02417497 0,0521105 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02417497 0,05204962 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02417497 0,05198889 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02417497 0,0519283 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02417497 0,05186784 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02417497 0,05180753 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02417497 0,05174736 ! cell-cell recognition GO:0009988 8 7 0,000 0,02417497 0,05168733 ! hormone catabolic process GO:0042447 7 7 0,000 0,02417497 0,05162744 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02417497 0,05156768 ! oxygen transport GO:0015671 7 7 0,000 0,02417497 0,05150807 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02417497 0,05144859 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02417497 0,05138925 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02417497 0,05133004 ! regulation of axon extension GO:0030516 7 7 0,000 0,02417497 0,05127098 ! cell killing GO:0001906 7 7 0,000 0,02417497 0,05121204 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02417497 0,05115325 ! adult feeding behavior GO:0008343 7 7 0,000 0,02417497 0,05109459 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02417497 0,05103606 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02417497 0,05097766 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02417497 0,0509194 ! response to cold GO:0009409 7 7 0,000 0,02417497 0,05086128 ! cell part morphogenesis GO:0032990 75 70 1,000 0,0243807 0,0512356 ! wound healing GO:0042060 74 70 1,000 0,0243807 0,05117725 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,02503449 0,05248984 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,02503449 0,05243019 ! regulation of cell activation GO:0050865 71 71 1,000 0,02503449 0,05237068 ! secretion by cell GO:0032940 75 72 1,000 0,02569548 0,05369249 ! muscle system process GO:0003012 72 72 1,000 0,02569548 0,05363168 ! sensory organ development GO:0007423 72 72 1,000 0,02569548 0,05357101 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,02569548 0,05351048 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02758248 0,0573753 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02758248 0,05731061 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02758248 0,05724608 ! positive regulation of translation GO:0045727 8 8 0,000 0,02758248 0,05718168 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02758248 0,05711743 ! superoxide anion generation GO:0042554 8 8 0,000 0,02758248 0,05705333 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02758248 0,05698937 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02758248 0,05692555 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02758248 0,05686187 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02758248 0,05679834 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02758248 0,05673495 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02758248 0,0566717 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,02758248 0,05660859 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02758248 0,05654562 ! zinc ion transport GO:0006829 8 8 0,000 0,02758248 0,0564828 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02758248 0,05642011 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02758248 0,05635756 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02758248 0,05629514 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02758248 0,05623287 ! lipid localization GO:0010876 8 8 0,000 0,02758248 0,05617074 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02758248 0,05610874 ! response to cAMP GO:0051591 8 8 0,000 0,02758248 0,05604687 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02758248 0,05598515 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02758248 0,05592356 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02758248 0,0558621 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02758248 0,05580079 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02758248 0,0557396 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02758248 0,05567855 ! sensory perception of taste GO:0050909 8 8 0,000 0,02758248 0,05561763 ! organelle fusion GO:0048284 8 8 0,000 0,02758248 0,05555685 ! pancreas development GO:0031016 8 8 0,000 0,02758248 0,0554962 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02758248 0,05543568 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02758248 0,05537529 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02758248 0,05531503 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02758248 0,05525491 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02758248 0,05519491 ! sperm motility GO:0030317 8 8 0,000 0,02758248 0,05513505 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02758248 0,05507531 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02758248 0,05501571 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02758248 0,05495623 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02758248 0,05489688 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02758248 0,05483767 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02758248 0,05477857 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02758248 0,05471961 ! Golgi organization GO:0007030 8 8 0,000 0,02758248 0,05466077 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02758248 0,05460206 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02758248 0,05454347 ! fructose metabolic process GO:0006000 8 8 0,000 0,02758248 0,05448501 ! mannose metabolic process GO:0006013 9 8 0,000 0,02758248 0,05442668 ! NAD metabolic process GO:0019674 8 8 0,000 0,02758248 0,05436847 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02758248 0,05431038 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02758248 0,05425242 ! response to fungus GO:0009620 8 8 0,000 0,02758248 0,05419458 ! stem cell differentiation GO:0048863 8 8 0,000 0,02758248 0,05413686 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02758248 0,05407927 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02758248 0,0540218 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02758248 0,05396445 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02758248 0,05390723 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02758248 0,05385012 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02758248 0,05379314 ! muscle cell development GO:0055001 8 8 0,000 0,02758248 0,05373627 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02758248 0,05367953 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02758248 0,05362291 ! sensory perception of pain GO:0019233 8 8 0,000 0,02758248 0,0535664 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02758248 0,05351002 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02758248 0,05345375 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02758248 0,0533976 ! chromatin silencing GO:0006342 8 8 0,000 0,02758248 0,05334157 ! tissue regeneration GO:0042246 8 8 0,000 0,02758248 0,05328566 ! salivary gland development GO:0007431 8 8 0,000 0,02758248 0,05322986 ! T cell homeostasis GO:0043029 8 8 0,000 0,02758248 0,05317418 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02758248 0,05311862 ! cofactor transport GO:0051181 8 8 0,000 0,02758248 0,05306317 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02758248 0,05300784 ! acid secretion GO:0046717 8 8 0,000 0,02758248 0,05295262 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02758248 0,05289752 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02758248 0,05284253 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02758248 0,05278766 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02758248 0,0527329 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02758248 0,05267825 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02758248 0,05262372 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02758248 0,0525693 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02758248 0,052515 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02758248 0,0524608 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02758248 0,05240672 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02758248 0,05235275 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02758248 0,05229888 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02758248 0,05224513 ! developmental induction GO:0031128 8 8 0,000 0,02758248 0,05219149 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02758248 0,05213796 ! actin filament polymerization GO:0030041 9 8 0,000 0,02758248 0,05208454 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,02758248 0,05203123 ! peptide hormone processing GO:0016486 8 8 0,000 0,02758248 0,05197803 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02758248 0,05192494 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02758248 0,05187195 ! response to oxidative stress GO:0006979 76 75 1,000 0,0277211 0,05207951 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,02841035 0,05332004 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,02841035 0,0532658 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,02910653 0,05451558 ! microtubule-based movement GO:0007018 82 78 1,000 0,02980959 0,0557757 ! metal ion homeostasis GO:0055065 78 78 1,000 0,02980959 0,05571914 ! nuclear transport GO:0051169 79 79 1,000 0,03051947 0,05698823 GO:0006913|nucleocytoplasmic transport, ! lactation GO:0007595 10 9 0,000 0,03097859 0,05778698 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03097859 0,05772855 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03097859 0,05767024 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03097859 0,05761204 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03097859 0,05755397 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03097859 0,05749601 ! viral genome replication GO:0019079 9 9 0,000 0,03097859 0,05743816 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03097859 0,05738044 ! copper ion transport GO:0006825 9 9 0,000 0,03097859 0,05732282 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03097859 0,05726533 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03097859 0,05720795 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03097859 0,05715068 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03097859 0,05709353 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03097859 0,0570365 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03097859 0,05697957 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03097859 0,05692277 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03097859 0,05686607 ! phospholipid efflux GO:0033700 9 9 0,000 0,03097859 0,05680949 ! response to alkaloid GO:0043279 10 9 0,000 0,03097859 0,05675302 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03097859 0,05669666 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03097859 0,05664041 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03097859 0,05658428 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03097859 0,05652825 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03097859 0,05647234 ! response to ethanol GO:0045471 9 9 0,000 0,03097859 0,05641654 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03097859 0,05636084 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03097859 0,05630526 ! methionine metabolic process GO:0006555 9 9 0,000 0,03097859 0,05624979 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03097859 0,05619442 ! cerebral cortex development GO:0021987 9 9 0,000 0,03097859 0,05613917 ! response to osmotic stress GO:0006970 9 9 0,000 0,03097859 0,05608402 ! pigmentation during development GO:0048066 9 9 0,000 0,03097859 0,05602898 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03097859 0,05597405 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03097859 0,05591923 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03097859 0,05586451 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03097859 0,05580991 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03097859 0,0557554 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03097859 0,05570101 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03097859 0,05564672 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03097859 0,05559254 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03097859 0,05553846 GO:0015800|acidic amino acid transport, ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03097859 0,05548448 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03097859 0,05543062 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03097859 0,05537685 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03097859 0,05532319 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03097859 0,05526964 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03097859 0,05521618 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03097859 0,05516283 ! DNA replication initiation GO:0006270 9 9 0,000 0,03097859 0,05510959 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03097859 0,05505645 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03097859 0,0550034 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03097859 0,05495047 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03097859 0,05489763 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03097859 0,05484489 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03097859 0,05479226 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03097859 0,05473973 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03097859 0,05468729 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03097859 0,05463496 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03097859 0,05458273 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03097859 0,0545306 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03097859 0,05447856 ! collagen catabolic process GO:0030574 9 9 0,000 0,03097859 0,05442663 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03097859 0,05437479 ! purine base metabolic process GO:0006144 9 9 0,000 0,03097859 0,05432306 ! gas transport GO:0015669 9 9 0,000 0,03097859 0,05427142 ! cholesterol efflux GO:0033344 9 9 0,000 0,03097859 0,05421988 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03097859 0,05416844 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03097859 0,05411709 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03097859 0,05406585 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03097859 0,0540147 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03097859 0,05396364 ! defense response to virus GO:0051607 9 9 0,000 0,03097859 0,05391269 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03097859 0,05386182 ! actin filament-based movement GO:0030048 9 9 0,000 0,03097859 0,05381106 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03097859 0,05376039 ! lymphocyte activation GO:0046649 82 81 1,000 0,03195951 0,05541052 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03436332 0,05952218 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03436332 0,05946629 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03436332 0,05941051 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03436332 0,05935483 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03436332 0,05929925 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03436332 0,05924378 ! neuron maturation GO:0042551 10 10 0,000 0,03436332 0,05918841 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03436332 0,05913315 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03436332 0,05907799 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03436332 0,05902293 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03436332 0,05896797 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03436332 0,05891312 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03436332 0,05885836 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03436332 0,05880371 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,03436332 0,05874917 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03436332 0,05869472 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03436332 0,05864037 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03436332 0,05858612 ! glial cell development GO:0021782 10 10 0,000 0,03436332 0,05853198 ! phototransduction GO:0007602 11 10 0,000 0,03436332 0,05847793 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03436332 0,05842399 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03436332 0,05837014 ! fat cell differentiation GO:0045444 10 10 0,000 0,03436332 0,05831639 ! myoblast differentiation GO:0045445 10 10 0,000 0,03436332 0,05826274 ! centrosome cycle GO:0007098 10 10 0,000 0,03436332 0,05820919 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03436332 0,05815574 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03436332 0,05810239 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03436332 0,05804913 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03436332 0,05799597 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03436332 0,05794291 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03436332 0,05788995 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03436332 0,05783708 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03436332 0,05778431 ! plasma membrane organization GO:0007009 10 10 0,000 0,03436332 0,05773163 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03436332 0,05767905 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03436332 0,05762657 ! lysosomal transport GO:0007041 10 10 0,000 0,03436332 0,05757418 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03436332 0,05752189 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03436332 0,05746969 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03436332 0,05741759 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03436332 0,05736558 ! exocrine system development GO:0035272 10 10 0,000 0,03436332 0,05731367 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03436332 0,05726184 ! embryo implantation GO:0007566 11 10 0,000 0,03436332 0,05721012 ! regulation of protein binding GO:0043393 11 10 0,000 0,03436332 0,05715848 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03436332 0,05710694 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03436332 0,0570555 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03436332 0,05700414 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03436332 0,05695288 ! protein export from nucleus GO:0006611 10 10 0,000 0,03436332 0,05690171 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03436332 0,05685063 ! cytolysis GO:0019835 10 10 0,000 0,03436332 0,05679964 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03436332 0,05674875 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03436332 0,05669794 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03436332 0,05664723 ! histone deacetylation GO:0016575 10 10 0,000 0,03436332 0,0565966 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03436332 0,05654607 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03436332 0,05649563 ! gland morphogenesis GO:0022612 10 10 0,000 0,03436332 0,05644528 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03436332 0,05639501 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03436332 0,05634484 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03436332 0,05629476 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03436332 0,05624476 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03436332 0,05619485 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03436332 0,05614504 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03436332 0,05609531 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03436332 0,05604566 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03436332 0,05599611 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03436332 0,05594664 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03436332 0,05589726 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03436332 0,05584797 ! gut development GO:0048565 10 10 0,000 0,03436332 0,05579877 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03436332 0,05574965 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03436332 0,05570062 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03436332 0,05565167 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03436332 0,05560281 ! protein stabilization GO:0050821 10 10 0,000 0,03436332 0,05555404 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,03491926 0,05640333 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,0356755 0,05757438 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 1,000 0,03720718 0,05999373 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,03720718 0,05994129 ! protein secretion GO:0009306 11 11 0,000 0,03773672 0,06074129 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,03773672 0,06068829 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,03773672 0,06063538 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,03773672 0,06058256 ! negative regulation of defense response GO:0031348 11 11 0,000 0,03773672 0,06052984 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,03773672 0,0604772 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,03773672 0,06042466 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,03773672 0,06037221 ! skin development GO:0043588 11 11 0,000 0,03773672 0,06031985 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,03773672 0,06026758 ! peroxisomal transport GO:0043574 11 11 0,000 0,03773672 0,0602154 ! protein amino acid methylation GO:0006479 11 11 0,000 0,03773672 0,06016331 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,03773672 0,06011131 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,03773672 0,0600594 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! T cell proliferation GO:0042098 11 11 0,000 0,03773672 0,06000758 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,03773672 0,05995585 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,03773672 0,05990421 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,03773672 0,05985265 ! spinal cord development GO:0021510 11 11 0,000 0,03773672 0,05980119 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,03773672 0,05974981 ! digestive system process GO:0022600 11 11 0,000 0,03773672 0,05969853 ! mitotic spindle organization GO:0007052 11 11 0,000 0,03773672 0,05964733 ! fucose metabolic process GO:0006004 11 11 0,000 0,03773672 0,05959621 ! membrane budding GO:0006900 11 11 0,000 0,03773672 0,05954519 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,03773672 0,05949425 ! monoamine transport GO:0015844 11 11 0,000 0,03773672 0,0594434 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,03773672 0,05939264 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,03773672 0,05934196 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,03773672 0,05929137 ! intermediate filament-based process GO:0045103 11 11 0,000 0,03773672 0,05924087 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,03773672 0,05919045 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,03773672 0,05914012 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,03773672 0,05908987 ! oogenesis GO:0048477 11 11 0,000 0,03773672 0,05903971 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,03773672 0,05898964 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,03773672 0,05893965 ! vitamin transport GO:0051180 11 11 0,000 0,03773672 0,05888974 ! muscle maintenance GO:0046716 12 11 0,000 0,03773672 0,05883992 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,03773672 0,05879018 ! steroid catabolic process GO:0006706 11 11 0,000 0,03773672 0,05874053 ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,03773672 0,05869096 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,03773672 0,05864147 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,03773672 0,05859207 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,03773672 0,05854275 ! chemotaxis GO:0006935 90 89 1,000 0,03798252 0,05887451 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,03798252 0,05882504 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,03876414 0,05998515 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,03955198 0,06115293 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,04034599 0,06232829 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,04109883 0,06343815 ! translational initiation GO:0006413 12 12 0,000 0,04109883 0,06338506 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04109883 0,06333206 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04109883 0,06327915 ! initiation of viral infection GO:0019059 12 12 0,000 0,04109883 0,06322633 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04109883 0,0631736 ! iron ion transport GO:0006826 13 12 0,000 0,04109883 0,06312096 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04109883 0,0630684 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04109883 0,06301593 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04109883 0,06296355 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04109883 0,06291125 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04109883 0,06285904 ! collagen metabolic process GO:0032963 12 12 0,000 0,04109883 0,06280692 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04109883 0,06275489 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04109883 0,06270294 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04109883 0,06265107 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04109883 0,06259929 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04109883 0,0625476 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04109883 0,062496 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04109883 0,06244447 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04109883 0,06239304 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04109883 0,06234168 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04109883 0,06229042 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04109883 0,06223923 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04109883 0,06218813 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04109883 0,06213712 ! acute-phase response GO:0006953 12 12 0,000 0,04109883 0,06208619 ! vacuolar transport GO:0007034 12 12 0,000 0,04109883 0,06203534 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04109883 0,06198457 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04109883 0,06193389 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04109883 0,06188329 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04109883 0,06183277 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,04109883 0,06178234 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04109883 0,06173199 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04109883 0,06168172 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04109883 0,06163153 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04109883 0,06158142 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04109883 0,06153139 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04109883 0,06148145 ! pallium development GO:0021543 13 12 0,000 0,04109883 0,06143159 ! cell fate determination GO:0001709 12 12 0,000 0,04109883 0,0613818 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04109883 0,0613321 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04109883 0,06128248 ! G1 phase GO:0051318 13 12 0,000 0,04109883 0,06123294 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04109883 0,06118348 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04109883 0,0611341 ! detection of light stimulus GO:0009583 13 12 0,000 0,04109883 0,0610848 ! synaptogenesis GO:0007416 12 12 0,000 0,04109883 0,06103557 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04109883 0,06098643 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04109883 0,06093737 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04109883 0,06088838 ! spermatid differentiation GO:0048515 13 12 0,000 0,04109883 0,06083948 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04109883 0,06079065 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04109883 0,0607419 ! neural tube closure GO:0001843 13 12 0,000 0,04109883 0,06069323 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04109883 0,06064463 ! negative regulation of translation GO:0017148 12 12 0,000 0,04109883 0,06059612 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04109883 0,06054768 ! regulation of cell growth GO:0001558 97 96 1,000 0,04358278 0,0641558 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04444968 0,0653797 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04444968 0,06532756 ! phenol metabolic process GO:0018958 13 13 0,000 0,04444968 0,06527551 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04444968 0,06522354 ! gluconeogenesis GO:0006094 13 13 0,000 0,04444968 0,06517165 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04444968 0,06511984 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04444968 0,06506812 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04444968 0,06501648 ! regeneration GO:0031099 13 13 0,000 0,04444968 0,06496492 ! keratinization GO:0031424 13 13 0,000 0,04444968 0,06491344 ! post-embryonic development GO:0009791 14 13 0,000 0,04444968 0,06486204 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04444968 0,06481073 ! vasculogenesis GO:0001570 13 13 0,000 0,04444968 0,06475949 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04444968 0,06470834 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04444968 0,06465727 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04444968 0,06460628 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04444968 0,06455537 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04444968 0,06450454 ! autophagy GO:0006914 13 13 0,000 0,04444968 0,06445379 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04444968 0,06440311 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04444968 0,06435252 ! ureteric bud development GO:0001657 13 13 0,000 0,04444968 0,06430201 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04444968 0,06425158 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04444968 0,06420122 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04444968 0,06415095 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04444968 0,06410075 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04444968 0,06405063 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04444968 0,06400059 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04444968 0,06395063 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04444968 0,06390075 ! vasodilation GO:0042311 14 13 0,000 0,04444968 0,06385094 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04444968 0,06380122 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04444968 0,06375156 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04444968 0,06370199 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04444968 0,06365249 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04444968 0,06360308 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04444968 0,06355373 ! immunoglobulin production GO:0002377 13 13 0,000 0,04444968 0,06350447 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04444968 0,06345528 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,04444968 0,06340616 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04444968 0,06335712 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04444968 0,06330816 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04444968 0,06325927 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04444968 0,06321046 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04444968 0,06316173 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04444968 0,06311307 GO:0019370|leukotriene biosynthetic process, ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04444968 0,06306448 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04444968 0,06301597 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04444968 0,06296753 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04444968 0,06291917 ! blastocyst development GO:0001824 13 13 0,000 0,04444968 0,06287088 ! telomere organization GO:0032200 13 13 0,000 0,04444968 0,06282267 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04444968 0,06277453 ! regulation of amine transport GO:0051952 13 13 0,000 0,04444968 0,06272646 ! tissue homeostasis GO:0001894 13 13 0,000 0,04444968 0,06267847 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04444968 0,06263055 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,04523695 0,06369114 ! response to hormone stimulus GO:0009725 102 100 1,000 0,04691448 0,06600258 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,04691448 0,06595223 ! hemopoiesis GO:0030097 104 100 1,000 0,04691448 0,06590196 ! neuron fate commitment GO:0048663 14 14 0,000 0,04778931 0,06707973 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,04778931 0,06702868 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,04778931 0,06697771 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,04778931 0,06692682 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,04778931 0,066876 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,04778931 0,06682526 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,04778931 0,06677459 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,04778931 0,06672401 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,04778931 0,0666735 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,04778931 0,06662306 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,04778931 0,06657271 ! vesicle docking GO:0048278 14 14 0,000 0,04778931 0,06652242 ! superoxide metabolic process GO:0006801 15 14 0,000 0,04778931 0,06647222 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,04778931 0,06642209 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,04778931 0,06637204 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,04778931 0,06632206 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,04778931 0,06627215 ! hair cycle GO:0042633 14 14 0,000 0,04778931 0,06622232 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,04778931 0,06617257 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,04778931 0,06612289 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,04778931 0,06607329 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,04778931 0,06602376 ! lysosome organization GO:0007040 14 14 0,000 0,04778931 0,0659743 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,04778931 0,06592492 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,04778931 0,06587561 GO:0045936|negative regulation of phosphate metabolic process, ! primary neural tube formation GO:0014020 15 14 0,000 0,04778931 0,06582638 ! peptide cross-linking GO:0018149 14 14 0,000 0,04778931 0,06577721 ! regulation of behavior GO:0050795 14 14 0,000 0,04778931 0,06572813 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,04778931 0,06567911 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,04778931 0,06563017 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,04778931 0,0655813 ! collagen fibril organization GO:0030199 14 14 0,000 0,04778931 0,06553251 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,04778931 0,06548378 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,04778931 0,06543513 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,04778931 0,06538656 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,04778931 0,06533805 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,04778931 0,06528961 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,04778931 0,06524125 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,04778931 0,06519296 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,05111774 0,06968195 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05111774 0,06963045 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05111774 0,06957903 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05111774 0,06952768 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05111774 0,0694764 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05111774 0,0694252 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05111774 0,06937408 ! response to vitamin GO:0033273 15 15 0,000 0,05111774 0,06932303 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,05111774 0,06927206 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05111774 0,06922116 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05111774 0,06917034 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05111774 0,06911959 ! ovarian follicle development GO:0001541 15 15 0,000 0,05111774 0,06906892 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05111774 0,06901832 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05111774 0,06896779 ! heme metabolic process GO:0042168 15 15 0,000 0,05111774 0,06891734 ! chromosome condensation GO:0030261 15 15 0,000 0,05111774 0,06886696 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05111774 0,06881666 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05111774 0,06876642 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05111774 0,06871627 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05111774 0,06866618 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05111774 0,06861617 ! phospholipid transport GO:0015914 15 15 0,000 0,05111774 0,06856623 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05111774 0,06851637 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05111774 0,06846657 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05111774 0,06841685 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05111774 0,0683672 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05111774 0,06831762 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05111774 0,06826812 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05111774 0,06821868 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05111774 0,06816932 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05111774 0,06812003 ! protein homooligomerization GO:0051260 15 15 0,000 0,05111774 0,06807081 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05111774 0,06802166 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,05443503 0,07238367 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,05443503 0,07233148 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05443503 0,07227937 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,05443503 0,07222733 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05443503 0,07217537 ! learning GO:0007612 16 16 0,000 0,05443503 0,07212348 ! circadian rhythm GO:0007623 16 16 0,000 0,05443503 0,07207167 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05443503 0,07201993 ! vacuole organization GO:0007033 16 16 0,000 0,05443503 0,07196827 ! vesicle targeting GO:0006903 17 16 0,000 0,05443503 0,07191668 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05443503 0,07186516 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,05443503 0,07181372 ! iron ion homeostasis GO:0055072 16 16 0,000 0,05443503 0,07176235 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05443503 0,07171105 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05443503 0,07165983 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05443503 0,07160868 ! cell fate specification GO:0001708 16 16 0,000 0,05443503 0,0715576 ! fatty acid transport GO:0015908 16 16 0,000 0,05443503 0,0715066 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05443503 0,07145567 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,05443503 0,07140481 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05443503 0,07135403 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05443503 0,07130331 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05443503 0,07125267 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05443503 0,0712021 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05443503 0,0711516 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05443503 0,07110118 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05443503 0,07105082 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05443503 0,07100054 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,0577412 0,07525957 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,0577412 0,07520639 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,0577412 0,07515327 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,0577412 0,07510024 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,0577412 0,07504727 ! leukocyte adhesion GO:0007159 17 17 0,000 0,0577412 0,07499439 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,0577412 0,07494157 ! sensory perception of smell GO:0007608 17 17 0,000 0,0577412 0,07488884 ! cell junction assembly GO:0034329 18 17 0,000 0,0577412 0,07483617 ! tissue remodeling GO:0048771 17 17 0,000 0,0577412 0,07478358 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,0577412 0,07473106 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,0577412 0,07467862 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,0577412 0,07462625 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,0577412 0,07457396 ! response to toxin GO:0009636 18 17 0,000 0,0577412 0,07452173 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,0577412 0,07446958 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,0577412 0,07441751 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,0577412 0,0743655 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,0577412 0,07431357 ! pigmentation GO:0043473 17 17 0,000 0,0577412 0,07426171 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,0577412 0,07420993 ! adult locomotory behavior GO:0008344 17 17 0,000 0,0577412 0,07415821 ! embryonic organ development GO:0048568 17 17 0,000 0,0577412 0,07410657 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,0577412 0,074055 ! liver development GO:0001889 17 17 0,000 0,0577412 0,0740035 ! gene silencing GO:0016458 17 17 0,000 0,0577412 0,07395207 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06103629 0,07811798 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,06103629 0,07806377 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06103629 0,07800963 ! meiosis I GO:0007127 18 18 0,000 0,06103629 0,07795557 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06103629 0,07790158 ! membrane docking GO:0022406 18 18 0,000 0,06103629 0,07784767 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06103629 0,07779384 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06103629 0,07774007 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06103629 0,07768639 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06103629 0,07763277 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,06103629 0,07757923 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06103629 0,07752577 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,06103629 0,07747237 ! ceramide metabolic process GO:0006672 18 18 0,000 0,06103629 0,07741906 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06103629 0,07736581 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06103629 0,07731264 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06103629 0,07725954 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06103629 0,07720651 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06103629 0,07715356 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06103629 0,07710068 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06103629 0,07704787 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06432034 0,08113784 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,06432034 0,08108234 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,06432034 0,08102692 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,06432034 0,08097158 ! feeding behavior GO:0007631 19 19 0,000 0,06432034 0,0809163 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,06432034 0,08086111 ! peroxisome organization GO:0007031 19 19 0,000 0,06432034 0,08080599 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06432034 0,08075094 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,06432034 0,08069597 ! metanephros development GO:0001656 19 19 0,000 0,06432034 0,08064108 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06432034 0,08058626 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06432034 0,08053151 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06432034 0,08047684 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,06432034 0,08042224 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,06432034 0,08036772 ! eye morphogenesis GO:0048592 19 19 0,000 0,06432034 0,08031327 ! regulation of cell shape GO:0008360 21 19 0,000 0,06432034 0,08025889 ! placenta development GO:0001890 19 19 0,000 0,06432034 0,08020459 ! response to heat GO:0009408 19 19 0,000 0,06432034 0,08015036 ! vesicle localization GO:0051648 20 19 0,000 0,06432034 0,08009621 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,06759338 0,08411519 ! negative regulation of binding GO:0051100 21 20 0,000 0,06759338 0,08405843 ! organic ether metabolic process GO:0018904 20 20 0,000 0,06759338 0,08400175 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,06759338 0,08394514 ! nucleus organization GO:0006997 20 20 0,000 0,06759338 0,08388862 ! phagocytosis GO:0006909 21 20 0,000 0,06759338 0,08383216 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,06759338 0,08377579 ! protein targeting to membrane GO:0006612 22 20 0,000 0,06759338 0,08371949 ! chromatin remodeling GO:0006338 20 20 0,000 0,06759338 0,08366326 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,06759338 0,08360711 ! lipid oxidation GO:0034440 20 20 0,000 0,06759338 0,08355104 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,06759338 0,08349504 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,06759338 0,08343911 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,06759338 0,08338326 ! RNA modification GO:0009451 20 20 0,000 0,06759338 0,08332749 ! single fertilization GO:0007338 21 20 0,000 0,06759338 0,08327179 ! regulation of B cell activation GO:0050864 20 20 0,000 0,06759338 0,08321616 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,07085544 0,08717395 ! mRNA catabolic process GO:0006402 21 21 0,000 0,07085544 0,0871158 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,07085544 0,08705772 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,07085544 0,08699972 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,07085544 0,0869418 ! Notch signaling pathway GO:0007219 22 21 0,000 0,07085544 0,08688395 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,07085544 0,08682618 ! organic anion transport GO:0015711 21 21 0,000 0,07085544 0,08676849 ! cholesterol transport GO:0030301 21 21 0,000 0,07085544 0,08671088 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,07085544 0,08665334 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,07085544 0,08659587 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,07085544 0,08653849 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,07085544 0,08648118 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,07085544 0,08642394 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,07085544 0,08636679 ! regulation of proteolysis GO:0030162 21 21 0,000 0,07085544 0,0863097 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,07085544 0,08625269 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,07085544 0,08619576 ! RNA export from nucleus GO:0006405 22 22 0,000 0,07410657 0,0900913 ! sister chromatid segregation GO:0000819 22 22 0,000 0,07410657 0,09003191 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,07410657 0,0899726 ! regulation of ion transport GO:0043269 22 22 0,000 0,07410657 0,08991337 ! odontogenesis GO:0042476 22 22 0,000 0,07410657 0,08985421 ! cell junction organization GO:0034330 23 22 0,000 0,07410657 0,08979514 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,07410657 0,08973614 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,07410657 0,08967722 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,07410657 0,08961837 ! ovulation cycle process GO:0022602 22 22 0,000 0,07410657 0,08955961 ! spindle organization GO:0007051 22 22 0,000 0,07410657 0,08950092 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,07410657 0,08944231 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,07410657 0,08938377 ! male sex differentiation GO:0046661 22 22 0,000 0,07410657 0,08932531 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,07410657 0,08926693 ! biopolymer methylation GO:0043414 22 22 0,000 0,07410657 0,08920862 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,07410657 0,08915039 ! detection of external stimulus GO:0009581 23 22 0,000 0,07410657 0,08909224 ! neuron migration GO:0001764 22 22 0,000 0,07410657 0,08903416 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,07410657 0,08897616 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,07410657 0,08891823 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,07410657 0,08886038 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,07410657 0,0888026 ! aerobic respiration GO:0009060 22 22 0,000 0,07410657 0,0887449 ! cytokine production GO:0001816 22 22 0,000 0,07410657 0,08868727 ! cytokinesis GO:0000910 23 22 0,000 0,07410657 0,08862972 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,07410657 0,08857225 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,07734679 0,09238505 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,07734679 0,09232522 ! viral infectious cycle GO:0019058 23 23 0,000 0,07734679 0,09226546 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,07734679 0,09220578 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,07734679 0,09214617 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,07734679 0,09208665 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,07734679 0,0920272 ! endocrine system development GO:0035270 23 23 0,000 0,07734679 0,09196783 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,07734679 0,09190853 ! female gonad development GO:0008585 23 23 0,000 0,07734679 0,09184931 ! lipid homeostasis GO:0055088 23 23 0,000 0,07734679 0,09179017 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,07734679 0,0917311 ! cell projection assembly GO:0030031 25 23 0,000 0,07734679 0,09167211 ! gliogenesis GO:0042063 24 24 0,000 0,08057614 0,09543819 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,08057614 0,0953769 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,08057614 0,09531568 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,08057614 0,09525454 ! ovulation cycle GO:0042698 24 24 0,000 0,08057614 0,09519348 ! fertilization GO:0009566 25 24 0,000 0,08057614 0,0951325 ! maintenance of protein location GO:0045185 25 24 0,000 0,08057614 0,09507159 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,08057614 0,09501077 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,08057614 0,09495002 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,08379466 0,09867959 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,08379466 0,09861658 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,08379466 0,09855365 ! cellular component disassembly GO:0022411 26 25 0,000 0,08379466 0,09849079 ! endosome transport GO:0016197 25 25 0,000 0,08379466 0,09842802 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,08379466 0,09836533 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,08379466 0,09830271 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,08379466 0,09824018 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,08379466 0,09817773 ! regulation of endocytosis GO:0030100 25 25 0,000 0,08379466 0,09811535 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,08379466 0,09805306 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,08379466 0,09799084 ! positive regulation of defense response GO:0031349 26 26 0,000 0,08700238 0,10167748 ! glycolysis GO:0006096 26 26 0,000 0,08700238 0,10161305 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,08700238 0,1015487 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,08700238 0,10148443 ! cellular defense response GO:0006968 26 26 0,000 0,08700238 0,10142024 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,08700238 0,10135613 ! regulation of protein secretion GO:0050708 26 26 0,000 0,08700238 0,1012921 ! germ cell development GO:0007281 27 26 0,000 0,08700238 0,10122815 ! pigment metabolic process GO:0042440 26 26 0,000 0,08700238 0,10116429 ! maintenance of location in cell GO:0051651 27 26 0,000 0,08700238 0,1011005 ! chloride transport GO:0006821 27 27 0,000 0,09019934 0,10474945 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,09019934 0,10468349 ! learning or memory GO:0007611 28 27 0,000 0,09019934 0,10461761 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,09019934 0,10455181 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,09019934 0,1044861 ! peptide metabolic process GO:0006518 29 27 0,000 0,09019934 0,10442047 ! inner ear development GO:0048839 27 27 0,000 0,09019934 0,10435492 ! defense response to bacterium GO:0042742 27 27 0,000 0,09019934 0,10428945 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,09019934 0,10422407 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,09019934 0,10415876 ! cell growth GO:0016049 27 27 0,000 0,09019934 0,10409354 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,09338557 0,10770313 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,09338557 0,10763577 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,09338557 0,1075685 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,09338557 0,10750131 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,09338557 0,10743421 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,09338557 0,10736719 ! developmental growth GO:0048589 28 28 0,000 0,09338557 0,10730025 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,0965611 0,11087982 ! antigen processing and presentation GO:0019882 29 29 0,000 0,0965611 0,11081078 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,0965611 0,11074182 ! tRNA processing GO:0008033 29 29 0,000 0,0965611 0,11067295 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,0965611 0,11060417 ! adult behavior GO:0030534 30 29 0,000 0,0965611 0,11053547 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,0965611 0,11046686 ! transition metal ion transport GO:0000041 31 30 0,000 0,09972597 0,11401673 ! RNA catabolic process GO:0006401 30 30 0,000 0,09972597 0,11394604 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,09972597 0,11387544 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,09972597 0,11380493 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,09972597 0,11373451 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,09972597 0,11366417 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,09972597 0,11359392 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,09972597 0,11352376 ! response to temperature stimulus GO:0009266 30 30 0,000 0,09972597 0,11345368 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,09972597 0,11338369 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,09972597 0,11331379 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,09972597 0,11324397 ! vesicle organization GO:0016050 30 30 0,000 0,09972597 0,11317424 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,09972597 0,11310459 ! establishment of organelle localization GO:0051656 31 30 0,000 0,09972597 0,11303503 ! regulation of translational initiation GO:0006446 31 31 0,000 0,10288022 0,11653856 ! membrane fusion GO:0006944 31 31 0,000 0,10288022 0,11646698 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,10288022 0,11639548 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,10288022 0,11632407 ! ion transmembrane transport GO:0034220 31 31 0,000 0,10288022 0,11625275 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,10288022 0,11618152 ! digestion GO:0007586 31 31 0,000 0,10288022 0,11611037 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,10288022 0,11603931 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,10288022 0,11596834 ! camera-type eye development GO:0043010 31 31 0,000 0,10288022 0,11589746 ! extracellular matrix organization GO:0030198 31 31 0,000 0,10288022 0,11582666 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,10288022 0,11575595 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,10288022 0,11568532 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,10288022 0,11561478 ! cell redox homeostasis GO:0045454 32 32 0,000 0,10602387 0,11907495 ! glucose catabolic process GO:0006007 32 32 0,000 0,10602387 0,11900243 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,10602387 0,11893 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,10602387 0,11885766 ! cell maturation GO:0048469 32 32 0,000 0,10602387 0,1187854 ! nuclear export GO:0051168 32 32 0,000 0,10602387 0,11871324 ! kidney development GO:0001822 32 32 0,000 0,10602387 0,11864116 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,10602387 0,11856917 ! maintenance of location GO:0051235 33 32 0,000 0,10602387 0,11849726 ! amino acid transport GO:0006865 33 33 0,000 0,10915696 0,12192502 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,10915696 0,12185117 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,10915696 0,12177741 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,10915696 0,12170374 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,10915696 0,12163016 ! regulation of actin filament length GO:0030832 34 34 0,000 0,11227953 0,12503394 ! response to metal ion GO:0010038 34 34 0,000 0,11227953 0,12495844 ! muscle cell differentiation GO:0042692 35 34 0,000 0,11227953 0,12488303 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,11227953 0,12480771 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,11227953 0,12473248 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,11227953 0,12465734 ! secondary metabolic process GO:0019748 34 34 0,000 0,11227953 0,12458229 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,11227953 0,12450733 ! detection of stimulus GO:0051606 36 34 0,000 0,11227953 0,12443246 ! acute inflammatory response GO:0002526 35 35 0,000 0,11539161 0,12780453 ! regulation of cellular component size GO:0032535 35 35 0,000 0,11539161 0,12772777 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,11539161 0,1276511 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,11539161 0,12757453 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,11539161 0,12749804 ! inorganic anion transport GO:0015698 35 35 0,000 0,11539161 0,12742165 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,11539161 0,12734535 ! regulation of immune effector process GO:0002697 35 35 0,000 0,11539161 0,12726914 ! hydrogen transport GO:0006818 36 36 0,000 0,11849323 0,13061186 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,11849323 0,13053379 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,11849323 0,13045581 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,11849323 0,13037793 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,11849323 0,13030014 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,11849323 0,13022244 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,11849323 0,13014483 ! gonad development GO:0008406 36 36 0,000 0,11849323 0,13006732 ! activation of immune response GO:0002253 36 36 0,000 0,11849323 0,1299899 ! coagulation GO:0050817 39 36 0,000 0,11849323 0,12991257 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,12158443 0,13322242 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,12158443 0,13314326 ! eye development GO:0001654 37 37 0,000 0,12158443 0,1330642 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,12158443 0,13298523 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,12158443 0,13290635 ! adaptive immune response GO:0002250 37 37 0,000 0,12158443 0,13282757 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! neurotransmitter transport GO:0006836 40 38 0,000 0,12466524 0,13611258 ! exocytosis GO:0006887 40 38 0,000 0,12466524 0,13603199 ! chromosome segregation GO:0007059 38 38 0,000 0,12466524 0,1359515 ! urogenital system development GO:0001655 38 38 0,000 0,12466524 0,1358711 ! hexose catabolic process GO:0019320 38 38 0,000 0,12466524 0,1357908 ! RNA elongation GO:0006354 38 38 0,000 0,12466524 0,13571059 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,12466524 0,13563048 ! hemostasis GO:0007599 42 39 0,000 0,12773569 0,13888901 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,12773569 0,13880712 ! response to unfolded protein GO:0006986 39 39 0,000 0,12773569 0,13872533 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,12773569 0,13864363 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,12773569 0,13856202 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,12773569 0,13848052 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,12773569 0,13839911 ! developmental maturation GO:0021700 39 39 0,000 0,12773569 0,13831779 ! limb development GO:0060173 39 39 0,000 0,12773569 0,13823657 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! myeloid cell differentiation GO:0030099 42 40 0,000 0,13079582 0,1414652 ! organelle localization GO:0051640 41 40 0,000 0,13079582 0,14138223 ! amine catabolic process GO:0009310 42 41 0,000 0,13384566 0,14459411 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,13384566 0,1445094 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,13384566 0,1444248 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,13384566 0,14434029 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,13384566 0,14425588 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,13688524 0,14744565 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,13688524 0,14735952 ! protein ubiquitination GO:0016567 43 42 0,000 0,13688524 0,1472735 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,13688524 0,14718757 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,13688524 0,14710175 ! forebrain development GO:0030900 43 42 0,000 0,13688524 0,14701603 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,13688524 0,1469304 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,13688524 0,14684488 ! reproductive structure development GO:0048608 43 43 0,000 0,1399146 0,15000734 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,1399146 0,14992012 ! alcohol catabolic process GO:0046164 43 43 0,000 0,1399146 0,14983301 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,1399146 0,149746 ! humoral immune response GO:0006959 44 44 0,000 0,14293377 0,15288853 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,14293377 0,15279985 ! mRNA transport GO:0051028 44 44 0,000 0,14293377 0,15271127 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,14293377 0,15262279 ! vitamin metabolic process GO:0006766 44 44 0,000 0,14293377 0,15253442 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,14293377 0,15244614 ! amine biosynthetic process GO:0009309 46 45 0,000 0,14594278 0,15556538 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,14594278 0,15547546 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,14594278 0,15538564 ! protein processing GO:0016485 45 45 0,000 0,14594278 0,15529592 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,14894166 0,15839555 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,14894166 0,1583042 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,14894166 0,15821296 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,14894166 0,15812182 ! sex differentiation GO:0007548 47 47 0,000 0,15193045 0,16120197 ! amine transport GO:0015837 47 47 0,000 0,15193045 0,16110922 ! rhythmic process GO:0048511 47 47 0,000 0,15193045 0,16101658 ! calcium ion transport GO:0006816 48 48 0,000 0,15490919 0,1640791 ! actin filament organization GO:0007015 50 48 0,000 0,15490919 0,16398485 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,15490919 0,16389072 ! DNA recombination GO:0006310 48 48 0,000 0,15490919 0,16379669 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,15787789 0,16683999 ! divalent metal ion transport GO:0070838 49 49 0,000 0,15787789 0,16674438 ! response to nutrient GO:0007584 49 49 0,000 0,15787789 0,16664888 ! response to bacterium GO:0009617 50 49 0,000 0,15787789 0,16655349 ! regulation of ligase activity GO:0051340 50 49 0,000 0,15787789 0,16645821 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,15787789 0,16636303 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,15787789 0,16626797 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,1608366 0,16928718 ! chromatin assembly GO:0031497 50 50 0,000 0,1608366 0,16919055 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,1608366 0,16909404 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,1608366 0,16899763 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,1608366 0,16890134 ! transcription initiation GO:0006352 50 50 0,000 0,1608366 0,16880515 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,1608366 0,16870908 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,16378534 0,17170443 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,16378534 0,17160681 ! positive regulation of immune response GO:0050778 51 51 0,000 0,16378534 0,17150931 ! rRNA metabolic process GO:0016072 51 51 0,000 0,16378534 0,17141191 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,16378534 0,17131463 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,16378534 0,17121746 ! protein maturation GO:0051604 51 51 0,000 0,16378534 0,1711204 ! RNA localization GO:0006403 52 52 0,000 0,16672415 0,17409213 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,16672415 0,17399355 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,16672415 0,17389508 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,16672415 0,17379673 ! sodium ion transport GO:0006814 53 53 0,000 0,16965307 0,17674992 ! tRNA metabolic process GO:0006399 53 53 0,000 0,16965307 0,17665006 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,16965307 0,17655031 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,16965307 0,17645068 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,16965307 0,17635116 ! response to virus GO:0009615 54 54 0,000 0,17257211 0,17928433 ! sulfur metabolic process GO:0006790 55 54 0,000 0,17257211 0,17918332 ! nucleosome organization GO:0034728 55 55 0,000 0,17548132 0,18210139 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,17548132 0,18199892 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,17548132 0,18189656 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,17548132 0,18179431 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,17838073 0,1846942 ! ATP metabolic process GO:0046034 57 57 0,000 0,18127036 0,18758073 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,18127036 0,18747546 ! innate immune response GO:0045087 58 58 0,000 0,18415026 0,19034712 ! carboxylic acid transport GO:0046942 59 59 0,000 0,18702044 0,19320553 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,18702044 0,19309729 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,18702044 0,19298918 ! immune effector process GO:0002252 59 59 0,000 0,18702044 0,19288118 ! potassium ion transport GO:0006813 60 60 0,000 0,18988094 0,1957218 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,18988094 0,1956124 ! protein polymerization GO:0051258 65 60 0,000 0,18988094 0,19550312 ! cellular respiration GO:0045333 62 61 0,000 0,1927318 0,19832759 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,1927318 0,19821692 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,1927318 0,19810637 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,1927318 0,19799594 ! lipid transport GO:0006869 62 62 0,000 0,19557305 0,20080286 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,19557305 0,20069105 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,19557305 0,20057937 ! glucose metabolic process GO:0006006 63 63 0,000 0,19840471 0,20337034 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,19840471 0,20325729 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,19840471 0,20314437 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,20122681 0,2059195 ! anion transport GO:0006820 65 65 0,000 0,20403939 0,2086818 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,20684248 0,21143133 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,20684248 0,21131413 ! DNA packaging GO:0006323 66 66 0,000 0,20684248 0,21119706 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,20684248 0,21108012 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,20963611 0,21381259 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,20963611 0,21369433 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,21242031 0,21641273 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,21242031 0,21629316 ! regulation of translation GO:0006417 69 69 0,000 0,2151951 0,21899756 ! sensory perception of sound GO:0007605 71 69 0,000 0,2151951 0,2188767 GO:0050954|sensory perception of mechanical stimulus, ! growth GO:0040007 70 70 0,000 0,21796053 0,22156716 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,21796053 0,22144501 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,22071661 0,22412161 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,22071661 0,22399819 ! ribosome biogenesis GO:0042254 71 71 0,000 0,22071661 0,22387491 ! regulation of cytokine production GO:0001817 72 72 0,000 0,22346339 0,22653632 ! electron transport chain GO:0022900 75 74 0,000 0,22892914 0,23194964 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,22892914 0,2318222 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,23164816 0,23444677 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,23164816 0,23431809 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,23975022 0,24238051 ! regulation of immune response GO:0050776 78 78 0,000 0,23975022 0,24224762 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,24510604 0,24752353 ! lipid catabolic process GO:0016042 82 81 0,000 0,24777037 0,25007711 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,25307203 0,25528831 ! ncRNA processing GO:0034470 83 83 0,000 0,25307203 0,25514866 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,25570941 0,25766672 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,25833786 0,26017305 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,25833786 0,26003096 ! hexose metabolic process GO:0019318 87 86 0,000 0,26095742 0,2625243 ! DNA replication GO:0006260 91 91 0,000 0,27392276 0,27541715 ! visual perception GO:0007601 93 92 0,000 0,27648954 0,27784635 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,27648954 0,27769494 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,27648954 0,27754369 ! epidermis development GO:0008544 94 94 0,000 0,28159703 0,28251678 ! cofactor metabolic process GO:0051186 95 94 0,000 0,28159703 0,28236307 ! endocytosis GO:0006897 99 98 0,000 0,29170855 0,29234304 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,29170855 0,29218416 ! anti-apoptosis GO:0006916 100 99 0,000 0,29421503 0,29453466 ! ectoderm development GO:0007398 99 99 0,000 0,29421503 0,29437476 ! response to other organism GO:0051707 101 100 0,000 0,29671302 0,29671302