pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6605-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phospholipid dephosphorylation GO:0046839 12 5 3,000 1,335E-10 3,213E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 3,999E-10 4,811E-07 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 9,314E-10 7,47E-07 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 1,86E-09 1,119E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 4,185E-09 2,014E-06 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 5,559E-09 2,229E-06 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 5,559E-09 1,911E-06 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 8,721E-09 2,623E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! endothelial cell migration GO:0043542 28 17 3,000 6,224E-08 1,664E-05 ! inositol metabolic process GO:0006020 28 17 3,000 6,224E-08 1,497E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 6,224E-08 1,361E-05 ! cardiac muscle tissue development GO:0048738 31 17 3,000 6,224E-08 1,248E-05 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 6,224E-08 1,152E-05 ! positive regulation of MAP kinase activity GO:0043406 160 93 5,000 8,233E-08 1,415E-05 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 2,000 1,198E-07 1,922E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 1,26E-07 1,895E-05 ! response to UV GO:0009411 104 53 4,000 1,543E-07 2,184E-05 ! nucleotide-excision repair GO:0006289 83 56 4,000 2,043E-07 2,731E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 2,291E-07 2,902E-05 GO:0010810|regulation of cell-substrate adhesion, ! male meiosis GO:0007140 7 6 2,000 2,393E-07 2,879E-05 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 2,000 2,393E-07 2,742E-05 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 2,901E-07 3,172E-05 ! base-excision repair GO:0006284 41 27 3,000 4,509E-07 4,717E-05 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 5,252E-07 5,265E-05 ! ER overload response GO:0006983 12 8 2,000 6,678E-07 6,427E-05 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 6,678E-07 6,179E-05 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 7,005E-07 6,242E-05 ! base-excision repair, AP site formation GO:0006285 14 9 2,000 1E-06 8,593E-05 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 1,327E-06 1,101E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 1,426E-06 1,144E-04 ! regulation of protein stability GO:0031647 73 37 3,000 1,668E-06 1,294E-04 ! regulation of cell adhesion GO:0030155 212 89 4,000 2,093E-06 1,573E-04 ! mesenchymal cell development GO:0014031 87 40 3,000 2,295E-06 1,674E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! polyol metabolic process GO:0019751 66 41 3,000 2,539E-06 1,797E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 3,083E-06 2,12E-04 ! deoxyribonucleotide catabolic process GO:0009264 19 13 2,000 3,382E-06 2,26E-04 ! response to X-ray GO:0010165 25 13 2,000 3,382E-06 2,199E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 3,71E-06 2,349E-04 ! negative regulation of cell migration GO:0030336 115 46 3,000 4,056E-06 2,502E-04 ! response to gamma radiation GO:0010332 28 14 2,000 4,297E-06 2,585E-04 ! positive regulation of cell cycle GO:0045787 89 48 3,000 4,819E-06 2,828E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 5,363E-06 3,072E-04 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 2,000 7,988E-06 4,469E-04 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 41 17 2,000 7,988E-06 4,368E-04 ! negative regulation of cell motion GO:0051271 134 55 3,000 8,344E-06 4,461E-04 ! regulation of DNA replication GO:0006275 101 56 3,000 8,97E-06 4,692E-04 ! positive regulation of cell migration GO:0030335 126 57 3,000 9,63E-06 4,93E-04 ! lipid modification GO:0030258 97 57 3,000 9,63E-06 4,827E-04 ! neuromuscular junction development GO:0007528 34 19 2,000 1,134E-05 5,57E-04 ! purine nucleotide catabolic process GO:0006195 29 19 2,000 1,134E-05 5,459E-04 ! D-ribose metabolic process GO:0006014 29 20 2,000 1,332E-05 6,286E-04 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,53E-05 7,08E-04 ! cell aging GO:0007569 44 21 2,000 1,552E-05 7,045E-04 ! regulation of vasoconstriction GO:0019229 39 21 2,000 1,552E-05 6,915E-04 ! DNA modification GO:0006304 34 21 2,000 1,552E-05 6,789E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,794E-05 7,708E-04 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 1,794E-05 7,572E-04 ! deoxyribonucleotide metabolic process GO:0009262 32 22 2,000 1,794E-05 7,442E-04 ! pentose metabolic process GO:0019321 35 24 2,000 2,35E-05 9,583E-04 ! protein tetramerization GO:0051262 52 24 2,000 2,35E-05 9,423E-04 ! phosphoinositide metabolic process GO:0030384 128 72 3,000 2,443E-05 9,636E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 2,666E-05 1,035E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 2,666E-05 1,018E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 2,666E-05 1,002E-03 ! positive regulation of JUN kinase activity GO:0043507 51 26 2,000 3,009E-05 1,114E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 3,379E-05 1,232E-03 ! regulation of JUN kinase activity GO:0043506 58 28 2,000 3,778E-05 1,357E-03 ! regulation of pH GO:0006885 43 29 2,000 4,207E-05 1,489E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 4,207E-05 1,467E-03 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 1,000 5,301E-05 1,822E-03 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 5,301E-05 1,796E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 5,301E-05 1,771E-03 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 1,000 5,301E-05 1,747E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 5,301E-05 1,724E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 5,301E-05 1,701E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 5,301E-05 1,678E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 5,301E-05 1,656E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 5,682E-05 1,753E-03 ! hindbrain development GO:0030902 61 32 2,000 5,682E-05 1,731E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 7,461E-05 2,244E-03 ! calcium-mediated signaling GO:0019722 62 35 2,000 7,461E-05 2,216E-03 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 7,876E-05 2,311E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 7,94E-05 2,302E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 7,94E-05 2,274E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! vascular smooth muscle contraction GO:0014829 13 6 1,000 7,94E-05 2,247E-03 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 7,94E-05 2,221E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! male sex determination GO:0030238 15 6 1,000 7,94E-05 2,196E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 7,94E-05 2,171E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neural nucleus development GO:0048857 14 6 1,000 7,94E-05 2,146E-03 ! response to UV-C GO:0010225 11 6 1,000 7,94E-05 2,123E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 7,94E-05 2,099E-03 ! progesterone metabolic process GO:0042448 10 6 1,000 7,94E-05 2,076E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 8,126E-05 2,102E-03 ! skeletal muscle tissue development GO:0007519 186 99 3,000 8,527E-05 2,183E-03 GO:0060538|skeletal muscle organ development, ! monovalent inorganic cation homeostasis GO:0055067 58 37 2,000 8,828E-05 2,236E-03 ! nucleotide catabolic process GO:0009166 61 38 2,000 9,569E-05 2,398E-03 ! mammary gland development GO:0030879 86 39 2,000 1,035E-04 2,567E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,11E-04 2,725E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 1,11E-04 2,697E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,11E-04 2,67E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,11E-04 2,644E-03 ! positive regulation of heart rate GO:0010460 10 7 1,000 1,11E-04 2,618E-03 ! phasic smooth muscle contraction GO:0014821 12 7 1,000 1,11E-04 2,593E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 1,11E-04 2,568E-03 ! centrosome duplication GO:0051298 13 7 1,000 1,11E-04 2,543E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,11E-04 2,519E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,11E-04 2,496E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 1,11E-04 2,473E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,11E-04 2,45E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,11E-04 2,428E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,11E-04 2,406E-03 ! diuresis GO:0030146 12 7 1,000 1,11E-04 2,384E-03 GO:0030147|natriuresis, ! negative regulation of nucleotide metabolic process GO:0045980 11 7 1,000 1,11E-04 2,363E-03 ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 1,11E-04 2,342E-03 ! dorsal/ventral pattern formation GO:0009953 68 41 2,000 1,203E-04 2,517E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,478E-04 3,065E-03 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 1,478E-04 3,039E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,478E-04 3,013E-03 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 1,000 1,478E-04 2,988E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,478E-04 2,963E-03 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 1,478E-04 2,938E-03 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 1,000 1,478E-04 2,914E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,478E-04 2,89E-03 ! blastocyst growth GO:0001832 19 8 1,000 1,478E-04 2,867E-03 ! double-strand break repair GO:0006302 81 44 2,000 1,487E-04 2,863E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,699E-04 3,244E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,699E-04 3,219E-03 ! regulation of JNK cascade GO:0046328 94 47 2,000 1,812E-04 3,406E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,897E-04 3,538E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,897E-04 3,511E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 1,897E-04 3,484E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,897E-04 3,458E-03 ! receptor clustering GO:0043113 18 9 1,000 1,897E-04 3,432E-03 ! motor axon guidance GO:0008045 16 9 1,000 1,897E-04 3,406E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,897E-04 3,381E-03 ! renal water homeostasis GO:0003091 14 9 1,000 1,897E-04 3,356E-03 ! regulation of muscle adaptation GO:0043502 14 9 1,000 1,897E-04 3,331E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 1,929E-04 3,364E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,929E-04 3,34E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,312E-04 3,973E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,368E-04 4,04E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,368E-04 4,012E-03 ! positive regulation of heart contraction GO:0045823 16 10 1,000 2,368E-04 3,984E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 2,368E-04 3,956E-03 ! multicellular organism growth GO:0035264 18 10 1,000 2,368E-04 3,929E-03 ! positive regulation of muscle contraction GO:0045933 14 10 1,000 2,368E-04 3,902E-03 ! midbrain development GO:0030901 13 10 1,000 2,368E-04 3,875E-03 ! multicellular organismal water homeostasis GO:0050891 15 10 1,000 2,368E-04 3,849E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 2,368E-04 3,823E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,368E-04 3,798E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 2,368E-04 3,773E-03 ! localization within membrane GO:0051668 20 10 1,000 2,368E-04 3,748E-03 ! synapse organization GO:0050808 85 52 2,000 2,449E-04 3,851E-03 ! activation of phospholipase C activity GO:0007202 103 54 2,000 2,74E-04 4,28E-03 GO:0010863|positive regulation of phospholipase C activity, ! heterocycle catabolic process GO:0046700 85 54 2,000 2,74E-04 4,252E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,889E-04 4,456E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,889E-04 4,428E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 2,889E-04 4,4E-03 ! vasoconstriction GO:0042310 18 11 1,000 2,889E-04 4,372E-03 ! oocyte differentiation GO:0009994 18 11 1,000 2,889E-04 4,345E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 2,889E-04 4,318E-03 ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 2,893E-04 4,296E-03 ! aging GO:0007568 103 55 2,000 2,893E-04 4,27E-03 ! skeletal muscle fiber development GO:0048741 111 56 2,000 3,051E-04 4,477E-03 ! muscle fiber development GO:0048747 112 57 2,000 3,216E-04 4,689E-03 ! regulation of phospholipase activity GO:0010517 106 57 2,000 3,216E-04 4,661E-03 ! positive regulation of lipase activity GO:0060193 108 58 2,000 3,385E-04 4,877E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 3,462E-04 4,958E-03 ! virus-host interaction GO:0019048 29 12 1,000 3,462E-04 4,929E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 3,462E-04 4,9E-03 ! cranial nerve development GO:0021545 20 12 1,000 3,462E-04 4,871E-03 ! histone acetylation GO:0016573 26 12 1,000 3,462E-04 4,843E-03 ! autonomic nervous system development GO:0048483 24 12 1,000 3,462E-04 4,815E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,462E-04 4,787E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 3,462E-04 4,76E-03 GO:0042130|negative regulation of T cell proliferation, ! DNA catabolic process GO:0006308 86 59 2,000 3,561E-04 4,868E-03 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 3,742E-04 5,087E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 4,085E-04 5,522E-03 GO:0000725|recombinational repair, ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 4,085E-04 5,491E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 4,085E-04 5,461E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 4,085E-04 5,431E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 4,321E-04 5,712E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,759E-04 6,257E-03 ! regulation of S phase GO:0033261 23 14 1,000 4,759E-04 6,223E-03 ! regulation of heart rate GO:0002027 24 14 1,000 4,759E-04 6,19E-03 ! cAMP biosynthetic process GO:0006171 23 14 1,000 4,759E-04 6,156E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 4,759E-04 6,123E-03 ! regulation of cellular response to stress GO:0080135 128 67 2,000 5,178E-04 6,627E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 5,178E-04 6,592E-03 ! negative regulation of cell growth GO:0030308 132 67 2,000 5,178E-04 6,557E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 5,408E-04 6,812E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 5,408E-04 6,777E-03 ! regulation of lipase activity GO:0060191 130 68 2,000 5,408E-04 6,742E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 5,483E-04 6,8E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 5,483E-04 6,765E-03 ! G1/S transition checkpoint GO:0031575 40 15 1,000 5,483E-04 6,731E-03 ! water homeostasis GO:0030104 27 15 1,000 5,483E-04 6,697E-03 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 1,000 5,483E-04 6,663E-03 ! negative regulation of cell size GO:0045792 134 69 2,000 5,644E-04 6,824E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 6,137E-04 7,383E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,257E-04 7,49E-03 ! activation of MAPKK activity GO:0000186 35 16 1,000 6,257E-04 7,453E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 6,257E-04 7,416E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 6,257E-04 7,38E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 6,393E-04 7,503E-03 ! meiosis GO:0007126 121 74 2,000 6,926E-04 8,089E-03 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of hormone secretion GO:0046888 25 17 1,000 7,081E-04 8,23E-03 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 7,081E-04 8,19E-03 ! neutrophil chemotaxis GO:0030593 27 17 1,000 7,081E-04 8,151E-03 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 7,081E-04 8,112E-03 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 7,202E-04 8,213E-03 ! meiotic cell cycle GO:0051321 122 75 2,000 7,202E-04 8,174E-03 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 7,954E-04 8,984E-03 GO:0050886|endocrine process, ! patterning of blood vessels GO:0001569 39 18 1,000 7,954E-04 8,942E-03 ! centrosome cycle GO:0007098 25 18 1,000 7,954E-04 8,901E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 7,954E-04 8,86E-03 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 7,954E-04 8,819E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 7,954E-04 8,778E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 7,954E-04 8,738E-03 ! nerve development GO:0021675 28 18 1,000 7,954E-04 8,699E-03 ! protein oligomerization GO:0051259 139 78 2,000 8,074E-04 8,79E-03 ! activation of protein kinase activity GO:0032147 147 79 2,000 8,379E-04 9,081E-03 ! positive regulation of hormone secretion GO:0046887 32 19 1,000 8,876E-04 9,577E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 8,876E-04 9,534E-03 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 8,876E-04 9,492E-03 ! peptide hormone secretion GO:0030072 31 19 1,000 8,876E-04 9,45E-03 ! response to hypoxia GO:0001666 171 81 2,000 9,01E-04 9,55E-03 ! response to oxygen levels GO:0070482 176 83 2,000 9,671E-04 0,01020528 ! protein amino acid acetylation GO:0006473 39 20 1,000 9,848E-04 0,01034646 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 9,848E-04 0,01030147 ! cAMP metabolic process GO:0046058 36 20 1,000 9,848E-04 0,01025688 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 9,848E-04 0,01021267 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 1,000 9,848E-04 0,01016884 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 9,848E-04 0,01012538 ! cellular response to starvation GO:0009267 33 20 1,000 9,848E-04 0,01008229 ! body fluid secretion GO:0007589 31 20 1,000 9,848E-04 0,01003957 ! peptide secretion GO:0002790 35 20 1,000 9,848E-04 9,997E-03 ! peptidyl-serine modification GO:0018209 43 20 1,000 9,848E-04 9,955E-03 ! negative regulation of T cell activation GO:0050868 40 20 1,000 9,848E-04 9,914E-03 ! negative regulation of coagulation GO:0050819 29 20 1,000 9,848E-04 9,872E-03 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 9,848E-04 9,831E-03 ! negative regulation of growth GO:0045926 155 84 2,000 1,001E-03 9,954E-03 ! hormone secretion GO:0046879 38 21 1,000 1,087E-03 0,01076055 ! smooth muscle contraction GO:0006939 46 21 1,000 1,087E-03 0,01071645 ! oogenesis GO:0048477 36 21 1,000 1,087E-03 0,01067271 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 1,087E-03 0,01062932 ! gland development GO:0048732 206 88 2,000 1,145E-03 0,01115799 ! microtubule-based transport GO:0010970 54 22 1,000 1,194E-03 0,01158056 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 1,194E-03 0,01153405 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 1,194E-03 0,01148791 ! renal system process GO:0003014 41 22 1,000 1,194E-03 0,01144214 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,194E-03 0,01139674 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,194E-03 0,01135169 ! ossification GO:0001503 188 90 2,000 1,222E-03 0,01157775 ! regulation of cell cycle process GO:0010564 149 90 2,000 1,222E-03 0,01153235 ! bone development GO:0060348 189 91 2,000 1,262E-03 0,01185924 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,305E-03 0,01222093 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,305E-03 0,01217357 ! sex determination GO:0007530 47 23 1,000 1,305E-03 0,01212656 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,305E-03 0,01207992 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 1,305E-03 0,01203364 ! hormone transport GO:0009914 40 23 1,000 1,305E-03 0,01198771 ! regulation of membrane potential GO:0042391 164 93 2,000 1,343E-03 0,01228966 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 1,343E-03 0,01224311 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 1,422E-03 0,01291006 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,422E-03 0,01286152 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,422E-03 0,01281335 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,422E-03 0,01276554 ! membrane depolarization GO:0051899 39 24 1,000 1,422E-03 0,01271809 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,422E-03 0,01267098 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,428E-03 0,01267971 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 1,428E-03 0,0126331 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,543E-03 0,01360103 ! myelination GO:0042552 45 25 1,000 1,543E-03 0,01355139 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 1,543E-03 0,01350211 ! receptor metabolic process GO:0043112 46 25 1,000 1,543E-03 0,01345319 ! response to starvation GO:0042594 42 25 1,000 1,543E-03 0,01340462 ! osteoblast differentiation GO:0001649 60 25 1,000 1,543E-03 0,0133564 ! neural crest cell development GO:0014032 54 25 1,000 1,543E-03 0,01330853 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 1,543E-03 0,013261 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 1,543E-03 0,01321381 ! somitogenesis GO:0001756 43 25 1,000 1,543E-03 0,01316695 ! regulation of blood coagulation GO:0030193 40 25 1,000 1,543E-03 0,01312043 ! cellular response to nutrient levels GO:0031669 41 25 1,000 1,543E-03 0,01307423 ! interphase GO:0051325 213 98 2,000 1,562E-03 0,01318288 ! cell cycle arrest GO:0007050 213 100 2,000 1,655E-03 0,01392012 ! embryonic pattern specification GO:0009880 44 26 1,000 1,669E-03 0,01399467 ! microtubule organizing center organization GO:0031023 39 26 1,000 1,669E-03 0,01394608 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,669E-03 0,01389783 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,669E-03 0,0138499 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 1,669E-03 0,01380231 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 1,669E-03 0,01375504 ! positive regulation of nuclear division GO:0051785 40 26 1,000 1,669E-03 0,01370809 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 1,669E-03 0,01366147 ! blastocyst development GO:0001824 49 26 1,000 1,669E-03 0,01361516 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 1,8E-03 0,01463272 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,8E-03 0,01458345 ! protein amino acid acylation GO:0043543 55 27 1,000 1,8E-03 0,01453451 ! mitochondrial membrane organization GO:0007006 57 27 1,000 1,8E-03 0,0144859 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 1,000 1,8E-03 0,01443762 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 1,8E-03 0,01438965 ! dendrite development GO:0016358 59 28 1,000 1,936E-03 0,01542208 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 1,936E-03 0,01537118 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 1,936E-03 0,01532062 ! complement activation, classical pathway GO:0006958 48 29 1,000 2,076E-03 0,01637694 ! respiratory gaseous exchange GO:0007585 57 29 1,000 2,076E-03 0,01632342 ! response to organic cyclic substance GO:0014070 55 29 1,000 2,076E-03 0,01627025 ! regulation of coagulation GO:0050818 46 29 1,000 2,076E-03 0,01621743 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 1,000 2,221E-03 0,01729363 ! ensheathment of neurons GO:0007272 57 30 1,000 2,221E-03 0,01723784 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,221E-03 0,01718241 ! regulation of B cell activation GO:0050864 50 30 1,000 2,221E-03 0,01712734 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 2,371E-03 0,0182227 ! peptide transport GO:0015833 55 31 1,000 2,371E-03 0,01816466 ! mesoderm formation GO:0001707 69 31 1,000 2,371E-03 0,018107 ! peripheral nervous system development GO:0007422 64 32 1,000 2,525E-03 0,01922417 ! BMP signaling pathway GO:0030509 64 32 1,000 2,525E-03 0,01916352 ! positive regulation of catabolic process GO:0009896 64 32 1,000 2,525E-03 0,01910326 ! DNA damage checkpoint GO:0000077 71 33 1,000 2,684E-03 0,02024161 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 2,684E-03 0,02017836 ! formation of primary germ layer GO:0001704 72 33 1,000 2,684E-03 0,0201155 ! leukocyte chemotaxis GO:0030595 50 33 1,000 2,684E-03 0,02005303 GO:0060326|cell chemotaxis, ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 2,847E-03 0,02120857 ! mesoderm morphogenesis GO:0048332 76 34 1,000 2,847E-03 0,02114311 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 2,847E-03 0,02107805 ! regulation of muscle development GO:0048634 70 35 1,000 3,015E-03 0,02225356 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 3,015E-03 0,02218551 ! negative regulation of secretion GO:0051048 63 35 1,000 3,015E-03 0,02211787 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 3,015E-03 0,02205064 ! female gonad development GO:0008585 58 35 1,000 3,015E-03 0,02198382 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 3,015E-03 0,02191741 ! DNA integrity checkpoint GO:0031570 75 36 1,000 3,188E-03 0,02310213 ! hormone biosynthetic process GO:0042446 57 36 1,000 3,188E-03 0,02303275 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,188E-03 0,02296379 ! cyclic nucleotide metabolic process GO:0009187 63 37 1,000 3,365E-03 0,02416731 ! glycogen metabolic process GO:0005977 61 37 1,000 3,365E-03 0,02409539 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 3,365E-03 0,02402389 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 3,547E-03 0,02524568 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 3,547E-03 0,02517121 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 3,547E-03 0,02509718 ! carbohydrate homeostasis GO:0033500 53 38 1,000 3,547E-03 0,02502358 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 3,547E-03 0,02495041 GO:0046660|female sex differentiation, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 3,547E-03 0,02487767 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 3,547E-03 0,02480535 GO:0006073|cellular glucan metabolic process, ! ear morphogenesis GO:0042471 60 39 1,000 3,733E-03 0,02603138 ! segmentation GO:0035282 67 39 1,000 3,733E-03 0,02595615 ! regulation of action potential in neuron GO:0019228 73 39 1,000 3,733E-03 0,02588134 ! regulation of hormone secretion GO:0046883 62 40 1,000 3,923E-03 0,02712459 ! cytokinesis GO:0000910 72 40 1,000 3,923E-03 0,02704687 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 4,118E-03 0,02831024 ! regulation of T cell proliferation GO:0042129 71 41 1,000 4,118E-03 0,02822958 ! T cell differentiation GO:0030217 81 41 1,000 4,118E-03 0,02814938 ! regulation of T cell differentiation GO:0045580 70 41 1,000 4,118E-03 0,02806964 ! female gamete generation GO:0007292 61 41 1,000 4,118E-03 0,02799035 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 4,318E-03 0,02926324 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 4,318E-03 0,02918104 ! regulation of tube size GO:0035150 71 42 1,000 4,318E-03 0,0290993 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 4,318E-03 0,02901802 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 4,318E-03 0,02893719 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 4,522E-03 0,0302192 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 4,522E-03 0,03013549 ! energy reserve metabolic process GO:0006112 74 43 1,000 4,522E-03 0,03005224 ! glucose transport GO:0015758 65 43 1,000 4,522E-03 0,02996945 ! hexose transport GO:0008645 67 44 1,000 4,73E-03 0,0312635 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 4,73E-03 0,03117785 ! B cell differentiation GO:0030183 107 44 1,000 4,73E-03 0,03109266 ! developmental growth GO:0048589 82 44 1,000 4,73E-03 0,03100794 ! leukocyte migration GO:0050900 68 45 1,000 4,942E-03 0,03231362 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 4,942E-03 0,03222604 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 5,159E-03 0,03354959 ! response to insulin stimulus GO:0032868 95 46 1,000 5,159E-03 0,03345916 ! positive regulation of protein transport GO:0051222 72 46 1,000 5,159E-03 0,03336921 ! positive regulation of DNA binding GO:0043388 73 47 1,000 5,381E-03 0,03470691 ! vascular process in circulatory system GO:0003018 80 47 1,000 5,381E-03 0,03461411 ! mitochondrial transport GO:0006839 82 48 1,000 5,606E-03 0,03596893 ! activation of caspase activity GO:0006919 84 48 1,000 5,606E-03 0,03587327 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 5,606E-03 0,03577811 ! regulation of action potential GO:0001508 95 49 1,000 5,836E-03 0,03714633 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 5,836E-03 0,03704832 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 5,836E-03 0,03695083 GO:0019724|B cell mediated immunity, ! regulation of ossification GO:0030278 117 50 1,000 6,07E-03 0,03833208 ! histone modification GO:0016570 91 50 1,000 6,07E-03 0,03823173 ! negative regulation of immune system process GO:0002683 95 50 1,000 6,07E-03 0,03813191 ! positive regulation of binding GO:0051099 78 51 1,000 6,308E-03 0,03952585 ! response to estrogen stimulus GO:0043627 93 51 1,000 6,308E-03 0,03942318 ! embryonic skeletal system development GO:0048706 85 51 1,000 6,308E-03 0,03932105 ! excretion GO:0007588 83 51 1,000 6,308E-03 0,03921944 ! regulation of angiogenesis GO:0045765 114 52 1,000 6,551E-03 0,04062235 ! regulation of muscle contraction GO:0006937 81 52 1,000 6,551E-03 0,04051792 ! positive regulation of growth GO:0045927 90 52 1,000 6,551E-03 0,04041403 ! covalent chromatin modification GO:0016569 101 52 1,000 6,551E-03 0,04031067 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 6,551E-03 0,04020784 ! cartilage development GO:0051216 90 52 1,000 6,551E-03 0,04010553 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 6,798E-03 0,04151045 ! cell maturation GO:0048469 100 53 1,000 6,798E-03 0,04140536 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 6,798E-03 0,0413008 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 7,049E-03 0,0427174 ! positive regulation of caspase activity GO:0043280 95 55 1,000 7,304E-03 0,04415201 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 7,304E-03 0,04404135 ! gastrulation GO:0007369 112 55 1,000 7,304E-03 0,04393125 ! heart morphogenesis GO:0003007 97 55 1,000 7,304E-03 0,04382169 ! positive regulation of organelle organization GO:0010638 100 56 1,000 7,563E-03 0,04526403 ! regulation of bone remodeling GO:0046850 137 57 1,000 7,826E-03 0,04672378 ! regulation of intracellular transport GO:0032386 101 57 1,000 7,826E-03 0,04660813 ! regulation of tissue remodeling GO:0034103 140 58 1,000 8,094E-03 0,04808169 ! positive regulation of secretion GO:0051047 95 59 1,000 8,365E-03 0,04957214 ! skeletal system morphogenesis GO:0048705 105 59 1,000 8,365E-03 0,04945034 ! regulation of heart contraction GO:0008016 110 60 1,000 8,641E-03 0,05095405 ! mesoderm development GO:0007498 119 61 1,000 8,92E-03 0,05247416 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 8,92E-03 0,05234617 ! ear development GO:0043583 103 62 1,000 9,204E-03 0,053879 ! viral reproductive process GO:0022415 126 62 1,000 9,204E-03 0,05374823 ! gonad development GO:0008406 98 62 1,000 9,204E-03 0,05361809 ! regulation of mitosis GO:0007088 105 63 1,000 9,491E-03 0,05515997 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 9,491E-03 0,05502705 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 9,783E-03 0,05658114 ! germ cell development GO:0007281 118 65 1,000 0,01007847 0,0581506 ! developmental maturation GO:0021700 116 66 1,000 0,01037794 0,05973523 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,01068133 0,0613348 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01068133 0,06118877 ! lung development GO:0030324 144 67 1,000 0,01068133 0,06104342 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01068133 0,06089877 ! adaptive immune response GO:0002250 119 67 1,000 0,01068133 0,0607548 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,01068133 0,06061151 ! viral reproduction GO:0016032 134 68 1,000 0,01098862 0,06220852 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,01098862 0,06206249 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01129979 0,06367048 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01156821 0,06503065 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01156821 0,06487906 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01156821 0,06472818 ! neuron fate determination GO:0048664 7 5 0,000 0,01156821 0,064578 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01156821 0,06442851 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01156821 0,06427971 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01156821 0,0641316 ! polyol transport GO:0015791 12 5 0,000 0,01156821 0,06398418 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01156821 0,06383742 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01156821 0,06369134 ! response to superoxide GO:0000303 10 5 0,000 0,01156821 0,06354593 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01156821 0,06340118 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01156821 0,06325708 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01156821 0,06311364 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01156821 0,06297085 ! female meiosis GO:0007143 7 5 0,000 0,01156821 0,0628287 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01156821 0,0626872 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01156821 0,06254633 ! cobalt ion transport GO:0006824 11 5 0,000 0,01156821 0,06240609 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01156821 0,06226648 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01156821 0,06212749 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01156821 0,06198912 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01156821 0,06185137 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01156821 0,06171423 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01156821 0,06157769 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01156821 0,06144176 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01156821 0,06130642 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01156821 0,06117168 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01156821 0,06103754 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01156821 0,06090397 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01156821 0,060771 ! negative chemotaxis GO:0050919 14 5 0,000 0,01156821 0,0606386 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01156821 0,06050677 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01156821 0,06037552 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01156821 0,06024484 ! behavioral response to pain GO:0048266 9 5 0,000 0,01156821 0,06011472 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01156821 0,05998516 ! Notch receptor processing GO:0007220 8 5 0,000 0,01156821 0,05985616 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01156821 0,05972772 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01156821 0,05959982 ! micturition GO:0060073 9 5 0,000 0,01156821 0,05947247 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01156821 0,05934566 ! copulation GO:0007620 9 5 0,000 0,01156821 0,0592194 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01156821 0,05909367 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01156821 0,05896847 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01156821 0,0588438 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01156821 0,05871965 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01156821 0,05859603 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01156821 0,05847293 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01156821 0,05835035 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01156821 0,05822828 ! grooming behavior GO:0007625 6 5 0,000 0,01156821 0,05810671 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01156821 0,05798566 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01156821 0,05786511 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01156821 0,05774505 ! response to protozoan GO:0001562 10 5 0,000 0,01156821 0,0576255 ! lymph vessel development GO:0001945 10 5 0,000 0,01156821 0,05750644 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01156821 0,05738787 ! endochondral ossification GO:0001958 16 5 0,000 0,01156821 0,05726979 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01156821 0,05715219 ! parathyroid gland development GO:0060017 13 5 0,000 0,01156821 0,05703507 ! anagen GO:0042640 6 5 0,000 0,01156821 0,05691844 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01156821 0,05680228 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01156821 0,05668659 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01156821 0,05657137 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01156821 0,05645663 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01156821 0,05634234 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01156821 0,05622852 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01156821 0,05611515 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01156821 0,05600225 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01156821 0,05588979 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01156821 0,05577779 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01156821 0,05566623 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01156821 0,05555512 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01156821 0,05544445 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01156821 0,05533423 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01156821 0,05522444 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01156821 0,05511508 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01156821 0,05500616 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01156821 0,05489767 ! histidine catabolic process GO:0006548 6 5 0,000 0,01156821 0,0547896 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01156821 0,05468196 ! microvillus organization GO:0032528 7 5 0,000 0,01156821 0,05457474 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01156821 0,05446794 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01156821 0,05436156 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01156821 0,05425559 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01156821 0,05415003 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01156821 0,05404489 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01156821 0,05394015 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01156821 0,05383581 ! polyol catabolic process GO:0046174 7 5 0,000 0,01156821 0,05373188 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01156821 0,05362836 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01156821 0,05352522 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01156821 0,05342249 ! muscle cell migration GO:0014812 8 5 0,000 0,01156821 0,05332015 ! mitochondrial fission GO:0000266 8 5 0,000 0,01156821 0,0532182 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01156821 0,05311663 ! mRNA transcription GO:0009299 9 5 0,000 0,01156821 0,05301546 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01156821 0,05291467 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01156821 0,05281426 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01156821 0,05271424 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01156821 0,05261459 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01156821 0,05251531 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01156821 0,05241641 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01156821 0,05231789 ! response to food GO:0032094 6 5 0,000 0,01156821 0,05221973 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01156821 0,05212194 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01156821 0,05202452 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01156821 0,05192746 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01156821 0,05183076 ! forebrain neuron development GO:0021884 13 5 0,000 0,01156821 0,05173442 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01156821 0,05163843 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01156821 0,05154281 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01156821 0,05144753 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01156821 0,05135261 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01156821 0,05125804 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01156821 0,05116382 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01156821 0,05106994 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01156821 0,0509764 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01156821 0,05088321 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01156821 0,05079036 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01156821 0,05069784 ! basic amino acid transport GO:0015802 11 5 0,000 0,01156821 0,05060567 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01156821 0,05051382 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01156821 0,05042231 ! depyrimidination GO:0045008 10 5 0,000 0,01156821 0,05033113 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01156821 0,05024028 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01156821 0,05014976 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01156821 0,05005956 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01156821 0,04996969 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01156821 0,04988014 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01156821 0,04979091 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01156821 0,04970199 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01156821 0,0496134 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01156821 0,04952512 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01156821 0,04943715 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01156821 0,0493495 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01156821 0,04926215 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01156821 0,04917512 ! response to arsenic GO:0046685 10 5 0,000 0,01156821 0,04908839 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01156821 0,04900197 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01156821 0,04891585 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01156821 0,04883003 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01156821 0,04874451 ! response to cadmium ion GO:0046686 7 5 0,000 0,01156821 0,04865929 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01156821 0,04857437 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01156821 0,04848975 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01156821 0,04840542 ! decidualization GO:0046697 11 5 0,000 0,01156821 0,04832138 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01156821 0,04823764 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01156821 0,04815418 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01156821 0,04807101 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01156821 0,04798813 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01156821 0,04790554 ! neural tube patterning GO:0021532 7 5 0,000 0,01156821 0,04782322 ! embryonic cleavage GO:0040016 6 5 0,000 0,01156821 0,04774119 ! peroxisome fission GO:0016559 5 5 0,000 0,01156821 0,04765945 ! histone demethylation GO:0016577 10 5 0,000 0,01156821 0,04757798 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01156821 0,04749679 ! mitotic recombination GO:0006312 9 5 0,000 0,01156821 0,04741587 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01156821 0,04733523 ! metaphase plate congression GO:0051310 7 5 0,000 0,01156821 0,04725487 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01156821 0,04717477 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01156821 0,04709495 ! enteric nervous system development GO:0048484 8 5 0,000 0,01156821 0,0470154 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01156821 0,04693612 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01156821 0,0468571 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01156821 0,04677835 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01156821 0,04669986 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01156821 0,04662164 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01156821 0,04654367 ! plasminogen activation GO:0031639 5 5 0,000 0,01156821 0,04646597 ! B cell homeostasis GO:0001782 13 5 0,000 0,01156821 0,04638853 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01156821 0,04631134 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01156821 0,04623441 ! metaphase GO:0051323 8 5 0,000 0,01156821 0,04615774 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01156821 0,04608132 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01156821 0,04600515 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01156821 0,04592923 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01156821 0,04585357 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01156821 0,04577815 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01156821 0,04570298 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01156821 0,04562806 ! response to redox state GO:0051775 5 5 0,000 0,01156821 0,04555338 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01156821 0,04547895 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01156821 0,04540476 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01156821 0,04533081 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01156821 0,0452571 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01156821 0,04518363 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01156821 0,0451104 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01156821 0,04503741 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01156821 0,04496465 ! striatum development GO:0021756 9 5 0,000 0,01156821 0,04489212 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01156821 0,04481983 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01156821 0,04474778 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01156821 0,04467595 ! glial cell migration GO:0008347 11 5 0,000 0,01156821 0,04460435 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01156821 0,04453299 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01156821 0,04446185 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01156821 0,04439094 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01156821 0,04432025 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01156821 0,04424979 ! neuroprotection GO:0043526 6 5 0,000 0,01156821 0,04417955 ! neural plate development GO:0001840 8 5 0,000 0,01156821 0,04410953 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01156821 0,04403974 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01156821 0,04397017 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01156821 0,04390081 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01156821 0,04383168 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01156821 0,04376276 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01156821 0,04369406 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01156821 0,04362557 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01156821 0,0435573 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01156821 0,04348924 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01156821 0,0434214 ! spindle assembly GO:0051225 6 5 0,000 0,01156821 0,04335376 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01156821 0,04328634 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01156821 0,04321912 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01156821 0,04315212 ! drug metabolic process GO:0017144 6 5 0,000 0,01156821 0,04308532 ! stem cell division GO:0017145 11 5 0,000 0,01156821 0,04301873 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01156821 0,04295234 ! organ regeneration GO:0031100 7 5 0,000 0,01156821 0,04288616 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01156821 0,04282018 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01156821 0,0427544 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01156821 0,04268883 ! respiratory tube development GO:0030323 150 70 1,000 0,01161482 0,04279519 ! reproductive structure development GO:0048608 113 71 1,000 0,01193369 0,04390286 ! humoral immune response GO:0006959 109 71 1,000 0,01193369 0,04383583 ! B cell activation GO:0042113 160 71 1,000 0,01193369 0,04376901 ! acute inflammatory response GO:0002526 113 72 1,000 0,01225639 0,04488414 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01225639 0,04481592 ! carbohydrate transport GO:0008643 110 72 1,000 0,01225639 0,04474792 ! respiratory system development GO:0060541 153 72 1,000 0,01225639 0,04468012 ! regulation of blood pressure GO:0008217 125 73 1,000 0,01258289 0,04580097 ! axon guidance GO:0007411 139 73 1,000 0,01258289 0,04573178 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01291318 0,0468614 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,01291318 0,04679083 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,01291318 0,04672047 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01291318 0,04665032 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,01324723 0,04778537 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,01324723 0,04771384 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,01324723 0,04764252 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,01358504 0,04878447 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,01358504 0,04871177 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,01358504 0,04863928 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01358504 0,04856701 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01386597 0,04949782 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01386597 0,04942449 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01386597 0,04935138 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01386597 0,04927848 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01386597 0,0492058 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01386597 0,04913333 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01386597 0,04906108 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01386597 0,04898904 ! sleep GO:0030431 13 6 0,000 0,01386597 0,0489172 ! response to oxygen radical GO:0000305 11 6 0,000 0,01386597 0,04884558 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01386597 0,04877417 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01386597 0,04870297 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01386597 0,04863197 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01386597 0,04856118 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01386597 0,0484906 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01386597 0,04842022 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01386597 0,04835005 ! forebrain regionalization GO:0021871 8 6 0,000 0,01386597 0,04828008 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01386597 0,04821031 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01386597 0,04814074 ! response to zinc ion GO:0010043 9 6 0,000 0,01386597 0,04807137 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01386597 0,04800221 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01386597 0,04793324 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01386597 0,04786447 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01386597 0,04779589 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01386597 0,04772751 ! malate metabolic process GO:0006108 11 6 0,000 0,01386597 0,04765933 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01386597 0,04759135 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01386597 0,04752355 ! protein refolding GO:0042026 15 6 0,000 0,01386597 0,04745595 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01386597 0,04738854 ! opsonization GO:0008228 8 6 0,000 0,01386597 0,04732132 ! mating behavior GO:0007617 7 6 0,000 0,01386597 0,0472543 ! neuron remodeling GO:0016322 15 6 0,000 0,01386597 0,04718746 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01386597 0,04712081 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01386597 0,04705435 ! equilibrioception GO:0050957 14 6 0,000 0,01386597 0,04698807 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01386597 0,04692199 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01386597 0,04685609 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01386597 0,04679037 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01386597 0,04672484 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01386597 0,04665949 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01386597 0,04659432 ! toxin metabolic process GO:0009404 11 6 0,000 0,01386597 0,04652933 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01386597 0,04646453 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01386597 0,04639991 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01386597 0,04633546 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01386597 0,0462712 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01386597 0,04620711 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01386597 0,0461432 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01386597 0,04607947 ! thymic T cell selection GO:0045061 12 6 0,000 0,01386597 0,04601591 ! protein lipoylation GO:0009249 10 6 0,000 0,01386597 0,04595252 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01386597 0,04588932 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01386597 0,04582628 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01386597 0,04576342 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01386597 0,04570073 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01386597 0,04563821 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,01386597 0,04557586 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01386597 0,04551369 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01386597 0,04545168 ! hyperosmotic response GO:0006972 9 6 0,000 0,01386597 0,04538984 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01386597 0,04532817 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01386597 0,04526667 ! urea metabolic process GO:0019627 7 6 0,000 0,01386597 0,04520533 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01386597 0,04514416 ! neutrophil activation GO:0042119 8 6 0,000 0,01386597 0,04508315 ! regulation of appetite GO:0032098 9 6 0,000 0,01386597 0,04502231 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01386597 0,04496163 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01386597 0,04490112 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01386597 0,04484077 ! neuron apoptosis GO:0051402 9 6 0,000 0,01386597 0,04478058 ! nucleoside salvage GO:0043174 9 6 0,000 0,01386597 0,04472055 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01386597 0,04466069 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01386597 0,04460098 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01386597 0,04454143 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01386597 0,04448204 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01386597 0,04442281 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01386597 0,04436374 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01386597 0,04430482 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01386597 0,04424606 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01386597 0,04418746 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01386597 0,04412901 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01386597 0,04407072 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01386597 0,04401258 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01386597 0,04395459 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01386597 0,04389675 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01386597 0,04383907 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01386597 0,04378154 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01386597 0,04372416 ! astrocyte development GO:0014002 15 6 0,000 0,01386597 0,04366693 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01386597 0,04360985 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01386597 0,04355292 ! interaction with symbiont GO:0051702 13 6 0,000 0,01386597 0,04349613 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01386597 0,0434395 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01386597 0,04338301 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01386597 0,04332667 ! response to copper ion GO:0046688 10 6 0,000 0,01386597 0,04327047 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01386597 0,04321442 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01386597 0,04315852 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01386597 0,04310276 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01386597 0,04304714 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01386597 0,04299167 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01386597 0,04293634 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01386597 0,04288115 ! hair follicle maturation GO:0048820 7 6 0,000 0,01386597 0,0428261 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01386597 0,0427712 ! Schwann cell development GO:0014044 15 6 0,000 0,01386597 0,04271643 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01386597 0,04266181 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01386597 0,04260732 ! subpallium development GO:0021544 10 6 0,000 0,01386597 0,04255298 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01386597 0,04249877 ! histone ubiquitination GO:0016574 8 6 0,000 0,01386597 0,0424447 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01386597 0,04239077 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01386597 0,04233697 ! G2 phase GO:0051319 16 6 0,000 0,01386597 0,04228331 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01386597 0,04222979 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01386597 0,0421764 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01386597 0,04212315 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01386597 0,04207003 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01386597 0,04201704 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01386597 0,04196419 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01386597 0,04191147 ! receptor internalization GO:0031623 10 6 0,000 0,01386597 0,04185889 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01386597 0,04180643 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01386597 0,04175411 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01386597 0,04170192 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01386597 0,04164985 ! protein deubiquitination GO:0016579 14 6 0,000 0,01386597 0,04159792 ! protein destabilization GO:0031648 9 6 0,000 0,01386597 0,04154612 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01386597 0,04149444 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01386597 0,0414429 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01386597 0,04139148 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01386597 0,04134019 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01386597 0,04128903 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01386597 0,04123799 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01386597 0,04118708 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01386597 0,04113629 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01386597 0,04108563 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01386597 0,0410351 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01386597 0,04098468 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01386597 0,0409344 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01386597 0,04088423 ! catecholamine transport GO:0051937 9 6 0,000 0,01386597 0,04083419 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01386597 0,04078427 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01386597 0,04073447 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01386597 0,0406848 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01386597 0,04063524 ! maternal placenta development GO:0001893 12 6 0,000 0,01386597 0,04058581 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01386597 0,04053649 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01386597 0,0404873 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01386597 0,04043822 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01386597 0,04038927 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01386597 0,04034043 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01386597 0,04029171 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01386597 0,0402431 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,01392657 0,04037026 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01392657 0,04032168 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,01427181 0,0412716 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,01462074 0,04222989 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01462074 0,04217926 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01462074 0,04212874 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,01462074 0,04207835 ! protein import into nucleus GO:0006606 158 80 1,000 0,01497335 0,04304166 ! T cell activation GO:0042110 168 81 1,000 0,01532961 0,04401317 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01532961 0,04396071 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,01532961 0,04390838 ! nuclear import GO:0051170 161 81 1,000 0,01532961 0,04385617 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,01568951 0,04483249 ! response to drug GO:0042493 143 82 1,000 0,01568951 0,0447793 ! response to nutrient GO:0007584 125 82 1,000 0,01568951 0,04472625 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01568951 0,04467332 ! tRNA transcription GO:0009304 14 7 0,000 0,01615847 0,04595423 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01615847 0,04589998 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01615847 0,04584585 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01615847 0,04579185 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01615847 0,04573798 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01615847 0,04568423 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01615847 0,04563061 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01615847 0,04557712 ! prostate gland development GO:0030850 13 7 0,000 0,01615847 0,04552375 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01615847 0,0454705 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01615847 0,04541738 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01615847 0,04536439 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01615847 0,04531152 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01615847 0,04525877 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01615847 0,04520614 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01615847 0,04515364 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01615847 0,04510125 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01615847 0,04504899 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01615847 0,04499685 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01615847 0,04494483 ! glycolipid transport GO:0046836 10 7 0,000 0,01615847 0,04489293 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01615847 0,04484115 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01615847 0,04478949 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01615847 0,04473795 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01615847 0,04468653 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01615847 0,04463523 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01615847 0,04458404 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01615847 0,04453297 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01615847 0,04448201 ! mRNA stabilization GO:0048255 18 7 0,000 0,01615847 0,04443118 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01615847 0,04438046 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01615847 0,04432985 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01615847 0,04427936 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01615847 0,04422899 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01615847 0,04417873 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01615847 0,04412858 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01615847 0,04407855 ! lipoprotein transport GO:0042953 14 7 0,000 0,01615847 0,04402863 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01615847 0,04397882 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01615847 0,04392913 ! rhythmic behavior GO:0007622 15 7 0,000 0,01615847 0,04387955 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01615847 0,04383008 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01615847 0,04378072 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01615847 0,04373147 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01615847 0,04368234 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01615847 0,04363331 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01615847 0,0435844 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01615847 0,04353559 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01615847 0,04348689 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01615847 0,0434383 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01615847 0,04338982 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01615847 0,04334145 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01615847 0,04329319 ! spinal cord patterning GO:0021511 13 7 0,000 0,01615847 0,04324503 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01615847 0,04319698 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01615847 0,04314904 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01615847 0,0431012 ! adrenal gland development GO:0030325 17 7 0,000 0,01615847 0,04305347 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01615847 0,04300584 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01615847 0,04295832 ! ovulation GO:0030728 9 7 0,000 0,01615847 0,04291091 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01615847 0,0428636 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01615847 0,04281639 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01615847 0,04276929 ! microtubule nucleation GO:0007020 20 7 0,000 0,01615847 0,04272229 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01615847 0,04267539 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01615847 0,0426286 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01615847 0,04258191 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01615847 0,04253532 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01615847 0,04248883 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01615847 0,04244245 ! galactose metabolic process GO:0006012 13 7 0,000 0,01615847 0,04239616 ! vesicle fusion GO:0006906 17 7 0,000 0,01615847 0,04234998 ! response to dietary excess GO:0002021 8 7 0,000 0,01615847 0,0423039 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01615847 0,04225791 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01615847 0,04221203 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01615847 0,04216625 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01615847 0,04212056 ! organ growth GO:0035265 15 7 0,000 0,01615847 0,04207498 ! purine salvage GO:0043101 10 7 0,000 0,01615847 0,04202949 ! nucleoside transport GO:0015858 8 7 0,000 0,01615847 0,0419841 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01615847 0,04193881 ! parturition GO:0007567 14 7 0,000 0,01615847 0,04189362 ! rRNA modification GO:0000154 14 7 0,000 0,01615847 0,04184853 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01615847 0,04180353 ! spindle checkpoint GO:0031577 15 7 0,000 0,01615847 0,04175863 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01615847 0,04171382 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01615847 0,04166911 ! macrophage differentiation GO:0030225 11 7 0,000 0,01615847 0,0416245 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01615847 0,04157998 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01615847 0,04153556 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01615847 0,04149123 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01615847 0,04144699 ! fibrinolysis GO:0042730 10 7 0,000 0,01615847 0,04140286 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01615847 0,04135881 ! eating behavior GO:0042755 7 7 0,000 0,01615847 0,04131486 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01615847 0,041271 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01615847 0,04122723 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01615847 0,04118356 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01615847 0,04113998 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01615847 0,04109649 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01615847 0,0410531 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01615847 0,04100979 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01615847 0,04096658 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01615847 0,04092345 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01615847 0,04088042 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01615847 0,04083748 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01615847 0,04079463 ! regulation of meiosis GO:0040020 12 7 0,000 0,01615847 0,04075187 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01615847 0,04070919 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01615847 0,04066661 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01615847 0,04062412 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01615847 0,04058171 ! transcription termination GO:0006353 13 7 0,000 0,01615847 0,0405394 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01615847 0,04049717 ! anaphase GO:0051322 17 7 0,000 0,01615847 0,04045503 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01615847 0,04041297 ! axonal fasciculation GO:0007413 18 7 0,000 0,01615847 0,04037101 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01615847 0,04032913 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01615847 0,04028734 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01615847 0,04024563 ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01615847 0,04020401 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01615847 0,04016248 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01615847 0,04012103 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01615847 0,04007967 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01615847 0,04003839 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01615847 0,0399972 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01615847 0,0399561 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01615847 0,03991507 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01615847 0,03987413 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01615847 0,03983328 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01615847 0,03979251 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01615847 0,03975182 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01615847 0,03971122 ! lymph node development GO:0048535 10 7 0,000 0,01615847 0,0396707 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01615847 0,03963026 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01615847 0,0395899 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01615847 0,03954962 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01615847 0,03950943 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01615847 0,03946932 ! adult feeding behavior GO:0008343 9 7 0,000 0,01615847 0,03942929 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01615847 0,03938934 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01615847 0,03934947 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01615847 0,03930969 ! muscle adaptation GO:0043500 14 7 0,000 0,01615847 0,03926998 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01615847 0,03923035 ! retina homeostasis GO:0001895 12 7 0,000 0,01615847 0,03919081 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01615847 0,03915134 ! protein prenylation GO:0018342 18 7 0,000 0,01615847 0,03911195 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01615847 0,03907264 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01615847 0,03903341 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01615847 0,03899426 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,01642014 0,03958603 ! negative regulation of transport GO:0051051 153 84 1,000 0,01642014 0,0395464 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,01642014 0,03950686 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01679084 0,0403584 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,0171651 0,0412168 ! mitochondrion organization GO:0007005 148 86 1,000 0,0171651 0,04117571 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,01754291 0,04204008 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,01754291 0,04199825 ! regulation of protein transport GO:0051223 154 87 1,000 0,01754291 0,0419565 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,01792424 0,04282595 ! regulation of neurological system process GO:0031644 148 88 1,000 0,01792424 0,04278346 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01844571 0,04398453 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01844571 0,04394098 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01844571 0,04389752 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01844571 0,04385414 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01844571 0,04381085 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01844571 0,04376764 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01844571 0,04372452 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01844571 0,04368149 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01844571 0,04363853 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01844571 0,04359567 ! meiotic prophase I GO:0007128 13 8 0,000 0,01844571 0,04355288 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01844571 0,04351019 ! oligopeptide transport GO:0006857 15 8 0,000 0,01844571 0,04346757 ! UTP metabolic process GO:0046051 8 8 0,000 0,01844571 0,04342504 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01844571 0,04338259 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01844571 0,04334022 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01844571 0,04329794 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01844571 0,04325574 ! succinate metabolic process GO:0006105 14 8 0,000 0,01844571 0,04321362 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01844571 0,04317159 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01844571 0,04312963 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01844571 0,04308776 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01844571 0,04304596 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01844571 0,04300425 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01844571 0,04296262 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01844571 0,04292107 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01844571 0,0428796 ! reflex GO:0060004 16 8 0,000 0,01844571 0,04283821 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01844571 0,0427969 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01844571 0,04275567 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01844571 0,04271452 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01844571 0,04267345 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01844571 0,04263246 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01844571 0,04259154 ! pigment granule organization GO:0048753 16 8 0,000 0,01844571 0,04255071 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01844571 0,04250995 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01844571 0,04246927 ! histidine metabolic process GO:0006547 16 8 0,000 0,01844571 0,04242867 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01844571 0,04238815 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01844571 0,0423477 ! glycine catabolic process GO:0006546 13 8 0,000 0,01844571 0,04230733 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01844571 0,04226704 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01844571 0,04222682 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01844571 0,04218668 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01844571 0,04214662 ! melanin metabolic process GO:0006582 15 8 0,000 0,01844571 0,04210663 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01844571 0,04206672 ! macrophage activation GO:0042116 12 8 0,000 0,01844571 0,04202688 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01844571 0,04198712 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01844571 0,04194744 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01844571 0,04190783 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01844571 0,04186829 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01844571 0,04182883 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01844571 0,04178944 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01844571 0,04175013 ! osteoblast development GO:0002076 16 8 0,000 0,01844571 0,04171089 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01844571 0,04167173 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01844571 0,04163264 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01844571 0,04159362 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01844571 0,04155467 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01844571 0,0415158 ! response to UV-B GO:0010224 16 8 0,000 0,01844571 0,041477 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01844571 0,04143827 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01844571 0,04139962 ! intermediate filament organization GO:0045109 12 8 0,000 0,01844571 0,04136103 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01844571 0,04132252 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01844571 0,04128408 ! cellular extravasation GO:0045123 12 8 0,000 0,01844571 0,04124572 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01844571 0,04120742 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01844571 0,04116919 ! response to antibiotic GO:0046677 11 8 0,000 0,01844571 0,04113104 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01844571 0,04109295 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01844571 0,04105494 ! DNA topological change GO:0006265 12 8 0,000 0,01844571 0,041017 ! response to tropane GO:0014073 15 8 0,000 0,01844571 0,04097912 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01844571 0,04094132 ! melanosome transport GO:0032402 13 8 0,000 0,01844571 0,04090358 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01844571 0,04086592 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01844571 0,04082833 ! mast cell activation GO:0045576 14 8 0,000 0,01844571 0,0407908 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01844571 0,04075334 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01844571 0,04071595 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01844571 0,04067863 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01844571 0,04064138 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01844571 0,0406042 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01844571 0,04056708 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01844571 0,04053004 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01844571 0,04049306 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01844571 0,04045614 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01844571 0,0404193 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01844571 0,04038252 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01844571 0,04034581 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01844571 0,04030916 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01844571 0,04027259 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01844571 0,04023607 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01844571 0,04019963 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01844571 0,04016325 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01844571 0,04012693 ! hormone catabolic process GO:0042447 17 8 0,000 0,01844571 0,04009069 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01844571 0,0400545 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01844571 0,04001839 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01844571 0,03998233 ! ATP catabolic process GO:0006200 11 8 0,000 0,01844571 0,03994635 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01844571 0,03991042 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01844571 0,03987456 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01844571 0,03983877 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01844571 0,03980304 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01844571 0,03976737 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01844571 0,03973177 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01844571 0,03969623 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01844571 0,03966076 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01844571 0,03962535 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01844571 0,03959 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01844571 0,03955471 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01844571 0,03951949 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01844571 0,03948433 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01844571 0,03944924 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01844571 0,0394142 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01844571 0,03937923 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01844571 0,03934432 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,01869743 0,03984589 ! sex differentiation GO:0007548 145 90 1,000 0,01869743 0,03981063 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,01988321 0,04229797 ! female pregnancy GO:0007565 164 94 1,000 0,02028534 0,0431153 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02028534 0,04307725 ! axon extension GO:0048675 15 9 0,000 0,02072772 0,04397785 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02072772 0,04393911 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02072772 0,04390043 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02072772 0,04386182 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02072772 0,04382327 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02072772 0,0437848 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02072772 0,04374639 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02072772 0,04370805 ! phosphate transport GO:0006817 19 9 0,000 0,02072772 0,04366978 ! reproductive behavior GO:0019098 19 9 0,000 0,02072772 0,04363157 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02072772 0,04359343 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02072772 0,04355536 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02072772 0,04351735 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02072772 0,04347941 ! GTP metabolic process GO:0046039 9 9 0,000 0,02072772 0,04344154 ! RNA methylation GO:0001510 15 9 0,000 0,02072772 0,04340373 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02072772 0,04336599 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02072772 0,04332831 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02072772 0,0432907 ! artery development GO:0060840 24 9 0,000 0,02072772 0,04325315 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02072772 0,04321567 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02072772 0,04317826 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02072772 0,04314091 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02072772 0,04310362 ! chemosensory behavior GO:0007635 20 9 0,000 0,02072772 0,0430664 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02072772 0,04302924 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02072772 0,04299214 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02072772 0,04295511 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02072772 0,04291815 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02072772 0,04288124 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02072772 0,0428444 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02072772 0,04280763 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02072772 0,04277091 ! protein targeting to ER GO:0045047 22 9 0,000 0,02072772 0,04273426 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02072772 0,04269768 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02072772 0,04266115 ! T cell selection GO:0045058 23 9 0,000 0,02072772 0,04262469 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02072772 0,04258829 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02072772 0,04255195 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02072772 0,04251567 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02072772 0,04247946 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02072772 0,04244331 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02072772 0,04240722 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02072772 0,04237119 ! mannose metabolic process GO:0006013 13 9 0,000 0,02072772 0,04233522 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02072772 0,04229931 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02072772 0,04226346 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02072772 0,04222768 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02072772 0,04219195 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02072772 0,04215629 ! ruffle organization GO:0031529 15 9 0,000 0,02072772 0,04212068 ! retinol metabolic process GO:0042572 18 9 0,000 0,02072772 0,04208514 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02072772 0,04204965 ! behavioral fear response GO:0001662 22 9 0,000 0,02072772 0,04201423 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02072772 0,04197886 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02072772 0,04194355 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02072772 0,04190831 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02072772 0,04187312 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02072772 0,04183799 ! segment specification GO:0007379 13 9 0,000 0,02072772 0,04180292 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02072772 0,04176791 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02072772 0,04173296 ! response to amine stimulus GO:0014075 13 9 0,000 0,02072772 0,04169807 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02072772 0,04166323 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02072772 0,04162845 ! erythrocyte development GO:0048821 15 9 0,000 0,02072772 0,04159373 ! gas homeostasis GO:0033483 16 9 0,000 0,02072772 0,04155907 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02072772 0,04152447 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02072772 0,04148992 ! postreplication repair GO:0006301 22 9 0,000 0,02072772 0,04145543 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02072772 0,041421 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02072772 0,04138663 ! icosanoid secretion GO:0032309 15 9 0,000 0,02072772 0,04135231 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02072772 0,04131805 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02072772 0,04128385 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02072772 0,0412497 ! regulation of cell division GO:0051302 15 9 0,000 0,02072772 0,04121561 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02072772 0,04118157 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02072772 0,0411476 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02072772 0,04111367 ! sterol catabolic process GO:0016127 11 9 0,000 0,02072772 0,04107981 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02072772 0,041046 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02072772 0,04101224 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02072772 0,04097854 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02072772 0,0409449 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02072772 0,04091131 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02072772 0,04087778 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02072772 0,0408443 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02072772 0,04081087 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02072772 0,0407775 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02072772 0,04074419 ! purine base metabolic process GO:0006144 21 9 0,000 0,02072772 0,04071093 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02072772 0,04067772 ! pigment granule transport GO:0051904 17 9 0,000 0,02072772 0,04064457 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02072772 0,04061147 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02072772 0,04057843 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02072772 0,04054544 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02072772 0,0405125 ! mitochondrion localization GO:0051646 15 9 0,000 0,02072772 0,04047962 ! leukocyte differentiation GO:0002521 202 96 1,000 0,02109978 0,04117282 ! positive regulation of immune response GO:0050778 156 96 1,000 0,02109978 0,04113945 ! protein ubiquitination GO:0016567 217 97 1,000 0,02151207 0,04190934 ! hormone metabolic process GO:0042445 157 97 1,000 0,02151207 0,04187544 ! regulation of protein localization GO:0032880 176 97 1,000 0,02151207 0,04184158 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02300449 0,04470824 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02300449 0,04467216 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02300449 0,04463613 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02300449 0,04460016 ! synapsis GO:0007129 13 10 0,000 0,02300449 0,04456425 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02300449 0,0445284 ! N-glycan processing GO:0006491 20 10 0,000 0,02300449 0,0444926 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02300449 0,04445687 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02300449 0,04442119 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02300449 0,04438557 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02300449 0,04435 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02300449 0,04431449 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02300449 0,04427904 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02300449 0,04424365 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02300449 0,04420831 ! androgen metabolic process GO:0008209 17 10 0,000 0,02300449 0,04417303 ! phospholipid efflux GO:0033700 16 10 0,000 0,02300449 0,0441378 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02300449 0,04410263 ! lung alveolus development GO:0048286 26 10 0,000 0,02300449 0,04406752 ! pathogenesis GO:0009405 13 10 0,000 0,02300449 0,04403246 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02300449 0,04399746 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02300449 0,04396251 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02300449 0,04392762 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02300449 0,04389278 ! endoderm development GO:0007492 16 10 0,000 0,02300449 0,043858 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02300449 0,04382328 ! arginine catabolic process GO:0006527 13 10 0,000 0,02300449 0,04378861 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02300449 0,04375399 ! proline metabolic process GO:0006560 13 10 0,000 0,02300449 0,04371943 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02300449 0,04368493 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02300449 0,04365047 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02300449 0,04361608 ! V(D)J recombination GO:0033151 28 10 0,000 0,02300449 0,04358173 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02300449 0,04354744 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02300449 0,04351321 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02300449 0,04347903 ! B cell proliferation GO:0042100 18 10 0,000 0,02300449 0,0434449 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02300449 0,04341082 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02300449 0,0433768 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02300449 0,04334284 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02300449 0,04330892 ! epithelial cell development GO:0002064 20 10 0,000 0,02300449 0,04327506 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02300449 0,04324125 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02300449 0,04320749 ! macroautophagy GO:0016236 17 10 0,000 0,02300449 0,04317379 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02300449 0,04314014 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02300449 0,04310654 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02300449 0,043073 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02300449 0,0430395 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02300449 0,04300606 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02300449 0,04297267 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02300449 0,04293933 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02300449 0,04290605 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02300449 0,04287281 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02300449 0,04283963 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02300449 0,0428065 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02300449 0,04277342 ! response to dsRNA GO:0043331 20 10 0,000 0,02300449 0,04274039 ! DNA ligation GO:0006266 19 10 0,000 0,02300449 0,04270741 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02300449 0,04267448 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02300449 0,0426416 ! melanosome localization GO:0032400 16 10 0,000 0,02300449 0,04260878 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02300449 0,042576 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02300449 0,04254327 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02300449 0,0425106 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02300449 0,04247797 ! mRNA cleavage GO:0006379 17 10 0,000 0,02300449 0,0424454 ! protein sumoylation GO:0016925 15 10 0,000 0,02300449 0,04241287 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02300449 0,0423804 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02300449 0,04234797 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02300449 0,0423156 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02300449 0,04228327 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02300449 0,04225099 ! salivary gland development GO:0007431 27 10 0,000 0,02300449 0,04221876 ! prophase GO:0051324 15 10 0,000 0,02300449 0,04218659 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02300449 0,04215446 ! apical protein localization GO:0045176 15 10 0,000 0,02300449 0,04212237 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02300449 0,04209034 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02300449 0,04205836 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02300449 0,04202642 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02300449 0,04199454 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02300449 0,0419627 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02300449 0,04193091 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02300449 0,04189917 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02300449 0,04186747 ! detection of calcium ion GO:0005513 23 10 0,000 0,02300449 0,04183583 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02300449 0,04180423 ! blastocyst formation GO:0001825 17 10 0,000 0,02300449 0,04177268 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02300449 0,04174118 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02300449 0,04170972 ! activation of innate immune response GO:0002218 12 10 0,000 0,02300449 0,04167831 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02300449 0,04164695 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02300449 0,04161564 ! response to nicotine GO:0035094 20 10 0,000 0,02300449 0,04158437 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02300449 0,04155315 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02300449 0,04152198 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02300449 0,04149085 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02527604 0,04555368 ! respiratory burst GO:0045730 17 11 0,000 0,02527604 0,04551958 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02527604 0,04548553 ! neuron fate specification GO:0048665 17 11 0,000 0,02527604 0,04545154 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02527604 0,0454176 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02527604 0,0453837 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02527604 0,04534986 ! thyroid gland development GO:0030878 26 11 0,000 0,02527604 0,04531607 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02527604 0,04528232 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02527604 0,04524863 ! response to pain GO:0048265 24 11 0,000 0,02527604 0,04521499 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02527604 0,0451814 ! T cell proliferation GO:0042098 26 11 0,000 0,02527604 0,04514785 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02527604 0,04511436 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02527604 0,04508092 ! bone resorption GO:0045453 16 11 0,000 0,02527604 0,04504753 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02527604 0,04501418 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02527604 0,04498089 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02527604 0,04494764 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02527604 0,04491445 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02527604 0,0448813 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02527604 0,0448482 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02527604 0,04481515 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02527604 0,04478215 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02527604 0,0447492 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,02527604 0,04471629 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02527604 0,04468344 ! UV protection GO:0009650 19 11 0,000 0,02527604 0,04465063 ! adult heart development GO:0007512 14 11 0,000 0,02527604 0,04461787 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02527604 0,04458516 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02527604 0,0445525 ! temperature homeostasis GO:0001659 17 11 0,000 0,02527604 0,04451988 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02527604 0,04448732 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02527604 0,0444548 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02527604 0,04442232 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02527604 0,0443899 ! regulation of organ growth GO:0046620 13 11 0,000 0,02527604 0,04435752 ! pigment granule localization GO:0051875 20 11 0,000 0,02527604 0,04432519 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02527604 0,04429291 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02527604 0,04426067 ! embryonic axis specification GO:0000578 18 11 0,000 0,02527604 0,04422848 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02527604 0,04419634 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02527604 0,04416424 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02527604 0,04413219 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02527604 0,04410019 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02527604 0,04406823 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02527604 0,04403632 ! zymogen activation GO:0031638 15 11 0,000 0,02527604 0,04400446 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02527604 0,04397264 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02527604 0,04394087 ! nucleosome positioning GO:0016584 15 11 0,000 0,02527604 0,04390914 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02527604 0,04387746 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02527604 0,04384583 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02527604 0,04381424 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02527604 0,04378269 ! acid secretion GO:0046717 18 11 0,000 0,02527604 0,04375119 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02527604 0,04371974 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02527604 0,04368833 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02527604 0,04365697 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02527604 0,04362565 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02527604 0,04359438 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02527604 0,04356315 ! cholesterol efflux GO:0033344 19 11 0,000 0,02527604 0,04353197 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02527604 0,04350083 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02527604 0,04346974 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02527604 0,04343869 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02527604 0,04340768 ! embryonic gut development GO:0048566 15 11 0,000 0,02527604 0,04337672 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02527604 0,0433458 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02527604 0,04331493 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02527604 0,0432841 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02527604 0,04325331 ! defense response to fungus GO:0050832 13 11 0,000 0,02527604 0,04322257 ! developmental induction GO:0031128 19 11 0,000 0,02527604 0,04319188 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02527604 0,04316122 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02527604 0,04313061 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02527604 0,04310004 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02527604 0,04306952 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02527604 0,04303904 ! nucleus localization GO:0051647 19 11 0,000 0,02527604 0,0430086 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02527604 0,04297821 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02754239 0,04679872 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02754239 0,0467657 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02754239 0,04673272 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02754239 0,04669978 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02754239 0,0466669 ! cartilage condensation GO:0001502 20 12 0,000 0,02754239 0,04663406 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02754239 0,04660126 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02754239 0,04656851 ! protein complex disassembly GO:0043241 27 12 0,000 0,02754239 0,04653581 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02754239 0,04650315 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02754239 0,04647054 ! hippocampus development GO:0021766 26 12 0,000 0,02754239 0,04643798 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,02754239 0,04640546 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02754239 0,04637298 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02754239 0,04634056 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02754239 0,04630817 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02754239 0,04627583 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02754239 0,04624354 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02754239 0,04621129 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02754239 0,04617909 ! drug transport GO:0015893 16 12 0,000 0,02754239 0,04614693 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02754239 0,04611482 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02754239 0,04608275 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02754239 0,04605073 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02754239 0,04601875 ! focal adhesion formation GO:0048041 35 12 0,000 0,02754239 0,04598681 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02754239 0,04595492 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02754239 0,04592307 ! forebrain cell migration GO:0021885 21 12 0,000 0,02754239 0,04589127 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02754239 0,04585951 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02754239 0,0458278 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02754239 0,04579613 ! entry into host cell GO:0030260 32 12 0,000 0,02754239 0,0457645 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02754239 0,04573291 ! monoamine transport GO:0015844 18 12 0,000 0,02754239 0,04570137 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02754239 0,04566988 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02754239 0,04563843 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02754239 0,04560702 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02754239 0,04557565 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02754239 0,04554433 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02754239 0,04551305 ! protein homotetramerization GO:0051289 21 12 0,000 0,02754239 0,04548181 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02754239 0,04545061 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02754239 0,04541946 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02754239 0,04538835 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02754239 0,04535729 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02754239 0,04532626 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02754239 0,04529528 ! fucose catabolic process GO:0019317 22 12 0,000 0,02754239 0,04526434 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02754239 0,04523344 ! histone methylation GO:0016571 26 12 0,000 0,02754239 0,04520259 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02754239 0,04517177 ! gland morphogenesis GO:0022612 29 12 0,000 0,02754239 0,045141 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02754239 0,04511027 ! T cell homeostasis GO:0043029 25 12 0,000 0,02754239 0,04507959 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02754239 0,04504894 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02754239 0,04501834 ! spleen development GO:0048536 22 12 0,000 0,02754239 0,04498778 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02754239 0,04495725 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02754239 0,04492678 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02754239 0,04489634 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02754239 0,04486594 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02754239 0,04483558 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02754239 0,04480527 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02754239 0,044775 ! response to cold GO:0009409 17 12 0,000 0,02754239 0,04474476 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02754239 0,04471457 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02754239 0,04468442 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02980355 0,0483203 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02980355 0,04828776 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02980355 0,04825527 ! peroxisomal transport GO:0043574 24 13 0,000 0,02980355 0,04822282 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02980355 0,04819041 ! lipid localization GO:0010876 28 13 0,000 0,02980355 0,04815805 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02980355 0,04812572 ! organelle fusion GO:0048284 32 13 0,000 0,02980355 0,04809345 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02980355 0,04806121 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02980355 0,04802902 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02980355 0,04799687 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02980355 0,04796477 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02980355 0,04793271 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02980355 0,04790069 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02980355 0,04786871 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02980355 0,04783678 ! methionine metabolic process GO:0006555 27 13 0,000 0,02980355 0,04780489 ! plasma membrane organization GO:0007009 24 13 0,000 0,02980355 0,04777304 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02980355 0,04774123 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02980355 0,04770947 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02980355 0,04767775 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02980355 0,04764607 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02980355 0,04761443 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02980355 0,04758283 ! exocrine system development GO:0035272 32 13 0,000 0,02980355 0,04755128 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02980355 0,04751977 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02980355 0,0474883 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02980355 0,04745687 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02980355 0,04742548 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02980355 0,04739414 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02980355 0,04736283 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02980355 0,04733157 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02980355 0,04730035 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02980355 0,04726917 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02980355 0,04723803 ! ribosome assembly GO:0042255 17 13 0,000 0,02980355 0,04720693 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02980355 0,04717587 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02980355 0,04714486 ! chromatin silencing GO:0006342 26 13 0,000 0,02980355 0,04711388 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02980355 0,04708295 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02980355 0,04705205 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02980355 0,0470212 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02980355 0,04699039 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02980355 0,04695961 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02980355 0,04692888 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02980355 0,04689819 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02980355 0,04686754 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02980355 0,04683692 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02980355 0,04680635 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02980355 0,04677582 ! embryonic placenta development GO:0001892 23 13 0,000 0,02980355 0,04674533 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02980355 0,04671487 ! insulin secretion GO:0030073 23 13 0,000 0,02980355 0,04668446 ! actin filament polymerization GO:0030041 24 13 0,000 0,02980355 0,04665409 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02980355 0,04662375 ! acrosome reaction GO:0007340 18 13 0,000 0,02980355 0,04659346 ! rRNA transcription GO:0009303 25 14 0,000 0,03205952 0,05008779 ! lactation GO:0007595 26 14 0,000 0,03205952 0,05005529 ! reproductive cellular process GO:0048610 20 14 0,000 0,03205952 0,05002282 ! tRNA modification GO:0006400 20 14 0,000 0,03205952 0,04999041 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03205952 0,04995803 ! water transport GO:0006833 21 14 0,000 0,03205952 0,04992569 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03205952 0,0498934 ! non-recombinational repair GO:0000726 25 14 0,000 0,03205952 0,04986115 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03205952 0,04982894 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03205952 0,04979677 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03205952 0,04976464 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03205952 0,04973256 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03205952 0,04970051 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03205952 0,04966851 ! palate development GO:0060021 31 14 0,000 0,03205952 0,04963655 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03205952 0,04960463 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03205952 0,04957275 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03205952 0,04954091 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03205952 0,04950911 ! arginine metabolic process GO:0006525 17 14 0,000 0,03205952 0,04947735 ! organic alcohol transport GO:0015850 29 14 0,000 0,03205952 0,04944564 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03205952 0,04941396 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03205952 0,04938233 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03205952 0,04935073 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03205952 0,04931918 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03205952 0,04928767 ! L-amino acid transport GO:0015807 30 14 0,000 0,03205952 0,04925619 ! bone mineralization GO:0030282 17 14 0,000 0,03205952 0,04922476 ! stem cell development GO:0048864 43 14 0,000 0,03205952 0,04919336 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03205952 0,04916201 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03205952 0,0491307 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03205952 0,04909942 ! cerebellum development GO:0021549 21 14 0,000 0,03205952 0,04906819 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03205952 0,049037 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03205952 0,04900584 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03205952 0,04897473 ! cofactor transport GO:0051181 26 14 0,000 0,03205952 0,04894365 ! NADP metabolic process GO:0006739 24 14 0,000 0,03205952 0,04891262 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03205952 0,04888162 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03205952 0,04885066 ! intestinal absorption GO:0050892 25 14 0,000 0,03205952 0,04881974 ! oxygen transport GO:0015671 21 14 0,000 0,03205952 0,04878887 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03205952 0,04875803 ! male genitalia development GO:0030539 24 14 0,000 0,03205952 0,04872722 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03205952 0,04869646 ! regulation of axon extension GO:0030516 37 14 0,000 0,03205952 0,04866574 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03205952 0,04863505 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03431032 0,05201677 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03431032 0,05198402 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,03431032 0,0519513 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03431032 0,05191863 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03431032 0,051886 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03431032 0,05185341 ! copper ion transport GO:0006825 20 15 0,000 0,03431032 0,05182085 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03431032 0,05178834 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03431032 0,05175588 ! sulfate transport GO:0008272 23 15 0,000 0,03431032 0,05172345 ! response to cAMP GO:0051591 22 15 0,000 0,03431032 0,05169106 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03431032 0,05165871 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03431032 0,0516264 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03431032 0,05159414 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03431032 0,05156191 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03431032 0,05152973 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03431032 0,05149758 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03431032 0,05146547 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03431032 0,05143341 ! pituitary gland development GO:0021983 29 15 0,000 0,03431032 0,05140138 ! vesicle coating GO:0006901 33 15 0,000 0,03431032 0,0513694 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03431032 0,05133745 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03431032 0,05130554 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03431032 0,05127368 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03431032 0,05124185 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03431032 0,05121006 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03431032 0,05117831 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03431032 0,05114661 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03431032 0,05111494 ! histone deacetylation GO:0016575 20 15 0,000 0,03431032 0,0510833 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03431032 0,05105171 ! tissue regeneration GO:0042246 26 15 0,000 0,03431032 0,05102016 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03431032 0,05098865 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03431032 0,05095717 ! muscle maintenance GO:0046716 26 15 0,000 0,03431032 0,05092574 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03431032 0,05089434 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03431032 0,05086298 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03431032 0,05083166 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03431032 0,05080038 ! cell killing GO:0001906 29 15 0,000 0,03431032 0,05076914 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03431032 0,05073794 ! detection of bacterium GO:0016045 18 15 0,000 0,03431032 0,05070677 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03431032 0,05067564 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03431032 0,05064455 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03431032 0,0506135 ! peptide hormone processing GO:0016486 23 15 0,000 0,03431032 0,05058249 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03655596 0,05386015 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03655596 0,05382719 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03655596 0,05379427 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03655596 0,05376139 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03655596 0,05372855 ! bone remodeling GO:0046849 27 16 0,000 0,03655596 0,05369575 ! filopodium assembly GO:0046847 32 16 0,000 0,03655596 0,05366299 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03655596 0,05363026 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03655596 0,05359758 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03655596 0,05356494 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03655596 0,05353234 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03655596 0,05349978 ! startle response GO:0001964 28 16 0,000 0,03655596 0,05346725 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03655596 0,05343477 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03655596 0,05340233 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03655596 0,05336992 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03655596 0,05333756 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03655596 0,05330523 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03655596 0,05327295 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03655596 0,0532407 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03655596 0,05320849 ! response to osmotic stress GO:0006970 25 16 0,000 0,03655596 0,05317632 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03655596 0,05314419 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03655596 0,0531121 ! fructose metabolic process GO:0006000 25 16 0,000 0,03655596 0,05308004 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03655596 0,05304803 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03655596 0,05301605 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03655596 0,05298412 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03655596 0,05295222 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03655596 0,05292036 ! axon cargo transport GO:0008088 43 16 0,000 0,03655596 0,05288853 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03655596 0,05285675 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03655596 0,052825 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,03655596 0,0527933 ! DNA replication initiation GO:0006270 27 16 0,000 0,03655596 0,05276163 ! neuron recognition GO:0008038 35 16 0,000 0,03655596 0,05273 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03655596 0,0526984 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03655596 0,05266685 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03655596 0,05263533 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03655596 0,05260385 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03655596 0,0525724 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03655596 0,052541 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03655596 0,05250963 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03655596 0,0524783 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03655596 0,05244701 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03655596 0,05241575 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03655596 0,05238453 ! defense response to virus GO:0051607 37 16 0,000 0,03655596 0,05235335 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03879645 0,05552901 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03879645 0,05549599 ! metencephalon development GO:0022037 30 17 0,000 0,03879645 0,05546302 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03879645 0,05543008 ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03879645 0,05539719 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03879645 0,05536433 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03879645 0,05533151 ! glial cell development GO:0021782 27 17 0,000 0,03879645 0,05529873 ! limbic system development GO:0021761 36 17 0,000 0,03879645 0,05526599 ! adult walking behavior GO:0007628 33 17 0,000 0,03879645 0,05523329 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03879645 0,05520063 ! heart looping GO:0001947 30 17 0,000 0,03879645 0,055168 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03879645 0,05513542 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03879645 0,05510287 ! myoblast differentiation GO:0045445 45 17 0,000 0,03879645 0,05507036 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03879645 0,05503789 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03879645 0,05500546 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03879645 0,05497306 ! glycine metabolic process GO:0006544 28 17 0,000 0,03879645 0,05494071 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03879645 0,05490839 ! NAD metabolic process GO:0019674 29 17 0,000 0,03879645 0,05487611 ! membrane budding GO:0006900 37 17 0,000 0,03879645 0,05484387 ! DNA integration GO:0015074 29 17 0,000 0,03879645 0,05481166 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03879645 0,05477949 ! regulation of protein binding GO:0043393 33 17 0,000 0,03879645 0,05474737 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03879645 0,05471527 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03879645 0,05468322 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03879645 0,05465121 ! genitalia development GO:0048806 30 17 0,000 0,03879645 0,05461923 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03879645 0,05458729 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03879645 0,05455538 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03879645 0,05452352 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03879645 0,05449169 ! steroid catabolic process GO:0006706 31 17 0,000 0,03879645 0,05445989 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03879645 0,05442814 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03879645 0,05439642 ! gas transport GO:0015669 25 17 0,000 0,03879645 0,05436474 ! organic cation transport GO:0015695 31 17 0,000 0,03879645 0,0543331 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03879645 0,05430149 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03879645 0,05426992 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03879645 0,05423838 ! microspike assembly GO:0030035 36 17 0,000 0,03879645 0,05420689 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03879645 0,05417543 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03879645 0,054144 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04103181 0,05723045 ! neuron maturation GO:0042551 42 18 0,000 0,04103181 0,05719729 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04103181 0,05716417 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04103181 0,05713109 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,04103181 0,05709805 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04103181 0,05706505 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04103181 0,05703208 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04103181 0,05699915 ! memory GO:0007613 31 18 0,000 0,04103181 0,05696626 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04103181 0,05693341 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04103181 0,05690059 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04103181 0,05686782 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04103181 0,05683508 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04103181 0,05680238 ! response to retinoic acid GO:0032526 26 18 0,000 0,04103181 0,05676971 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04103181 0,05673709 ! response to fungus GO:0009620 21 18 0,000 0,04103181 0,0567045 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04103181 0,05667194 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04103181 0,05663943 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04103181 0,05660695 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04103181 0,05657451 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04103181 0,05654211 ! vitamin transport GO:0051180 27 18 0,000 0,04103181 0,05650975 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04103181 0,05647742 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04103181 0,05644513 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04103181 0,05641287 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04103181 0,05638066 ! protein secretion GO:0009306 39 19 0,000 0,04326204 0,05941123 ! positive regulation of translation GO:0045727 30 19 0,000 0,04326204 0,05937733 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04326204 0,05934348 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04326204 0,05930967 ! skin development GO:0043588 36 19 0,000 0,04326204 0,05927589 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04326204 0,05924216 ! lipid phosphorylation GO:0046834 35 19 0,000 0,04326204 0,05920846 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04326204 0,0591748 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04326204 0,05914117 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04326204 0,05910759 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04326204 0,05907405 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04326204 0,05904054 ! cerebral cortex development GO:0021987 36 19 0,000 0,04326204 0,05900707 ! pigmentation during development GO:0048066 41 19 0,000 0,04326204 0,05897364 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04326204 0,05894024 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04326204 0,05890689 ! heme metabolic process GO:0042168 36 19 0,000 0,04326204 0,05887357 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04326204 0,05884029 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04326204 0,05880704 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04326204 0,05877384 ! peptide cross-linking GO:0018149 37 19 0,000 0,04326204 0,05874067 ! protein export from nucleus GO:0006611 36 19 0,000 0,04326204 0,05870754 ! heart process GO:0003015 30 19 0,000 0,04326204 0,05867445 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04326204 0,05864139 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04326204 0,05860837 ! visual learning GO:0008542 36 19 0,000 0,04326204 0,05857539 ! cellular pigmentation GO:0033059 36 19 0,000 0,04326204 0,05854245 ! G1 phase GO:0051318 40 19 0,000 0,04326204 0,05850954 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04326204 0,05847667 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04326204 0,05844383 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04326204 0,05841104 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04326204 0,05837828 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04326204 0,05834555 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04326204 0,05831287 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04326204 0,05828022 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04326204 0,0582476 ! cilium assembly GO:0042384 37 19 0,000 0,04326204 0,05821503 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04548716 0,06117502 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04548716 0,06114084 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04548716 0,0611067 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04548716 0,0610726 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04548716 0,06103854 ! response to vitamin GO:0033273 31 20 0,000 0,04548716 0,06100452 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04548716 0,06097053 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04548716 0,06093658 ! response to alkaloid GO:0043279 38 20 0,000 0,04548716 0,06090267 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04548716 0,0608688 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04548716 0,06083497 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04548716 0,06080117 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04548716 0,06076741 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04548716 0,06073369 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04548716 0,0607 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04548716 0,06066636 ! stem cell differentiation GO:0048863 53 20 0,000 0,04548716 0,06063275 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04548716 0,06059917 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04548716 0,06056564 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04548716 0,06053214 ! sensory perception of pain GO:0019233 30 20 0,000 0,04548716 0,06049868 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04548716 0,06046525 ! diencephalon development GO:0021536 34 20 0,000 0,04548716 0,06043186 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04548716 0,06039851 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04548716 0,0603652 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04548716 0,06033192 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04548716 0,06029868 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04548716 0,06026548 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04548716 0,06023231 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04548716 0,06019918 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04548716 0,06016608 ! regulation of glucose import GO:0046324 29 20 0,000 0,04548716 0,06013303 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04548716 0,0601 ! actin filament-based movement GO:0030048 43 20 0,000 0,04548716 0,06006702 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04548716 0,06003407 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04548716 0,06000115 ! negative regulation of translation GO:0017148 29 20 0,000 0,04548716 0,05996828 ! regulation of cell killing GO:0031341 42 21 0,000 0,04770718 0,06286061 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04770718 0,0628262 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04770718 0,06279183 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04770718 0,0627575 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04770718 0,06272321 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04770718 0,06268895 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04770718 0,06265473 ! axis specification GO:0009798 38 21 0,000 0,04770718 0,06262055 ! ovarian follicle development GO:0001541 35 21 0,000 0,04770718 0,06258641 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04770718 0,0625523 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04770718 0,06251823 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04770718 0,0624842 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04770718 0,0624502 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04770718 0,06241624 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04770718 0,06238232 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04770718 0,06234844 ! cytolysis GO:0019835 24 21 0,000 0,04770718 0,06231459 ! vasodilation GO:0042311 39 21 0,000 0,04770718 0,06228078 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04770718 0,062247 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04770718 0,06221326 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04770718 0,06217956 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04770718 0,0621459 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04770718 0,06211227 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04770718 0,06207868 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04770718 0,06204512 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04770718 0,0620116 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04770718 0,06197812 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04770718 0,06194467 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04770718 0,06191126 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04770718 0,06187788 ! collagen catabolic process GO:0030574 28 21 0,000 0,04770718 0,06184454 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04770718 0,06181124 ! gut development GO:0048565 39 21 0,000 0,04770718 0,06177797 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04992211 0,0646114 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04992211 0,06457666 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04992211 0,06454196 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04992211 0,0645073 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04992211 0,06447267 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04992211 0,06443808 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04992211 0,06440353 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04992211 0,06436902 ! regeneration GO:0031099 41 22 0,000 0,04992211 0,06433454 ! keratinization GO:0031424 28 22 0,000 0,04992211 0,0643001 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04992211 0,0642657 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04992211 0,06423133 ! sensory perception of taste GO:0050909 28 22 0,000 0,04992211 0,064197 ! vacuolar transport GO:0007034 36 22 0,000 0,04992211 0,06416271 ! lysosome organization GO:0007040 41 22 0,000 0,04992211 0,06412845 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04992211 0,06409423 ! fucose metabolic process GO:0006004 39 22 0,000 0,04992211 0,06406005 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04992211 0,0640259 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04992211 0,06399179 ! ureteric bud development GO:0001657 43 22 0,000 0,04992211 0,06395772 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04992211 0,06392368 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04992211 0,06388968 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04992211 0,06385571 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04992211 0,06382178 ! sarcomere organization GO:0045214 30 22 0,000 0,04992211 0,06378789 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04992211 0,06375403 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04992211 0,06372021 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04992211 0,06368642 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04992211 0,06365267 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,04992211 0,06361896 ! protein stabilization GO:0050821 39 22 0,000 0,04992211 0,06358528 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05213196 0,06636481 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05213196 0,06632971 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05213196 0,06629466 ! gluconeogenesis GO:0006094 33 23 0,000 0,05213196 0,06625964 ! viral genome replication GO:0019079 41 23 0,000 0,05213196 0,06622465 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05213196 0,0661897 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05213196 0,06615479 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05213196 0,06611992 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05213196 0,06608508 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05213196 0,06605028 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05213196 0,06601552 ! visual behavior GO:0007632 42 23 0,000 0,05213196 0,06598079 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05213196 0,0659461 ! response to ethanol GO:0045471 46 23 0,000 0,05213196 0,06591145 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05213196 0,06587683 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05213196 0,06584225 ! peroxisome organization GO:0007031 37 23 0,000 0,05213196 0,06580771 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05213196 0,0657732 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05213196 0,06573873 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05213196 0,06570429 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05213196 0,06566989 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05213196 0,06563553 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05213196 0,0656012 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05213196 0,06556691 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05213196 0,06553265 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05213196 0,06549843 ! fatty acid transport GO:0015908 44 23 0,000 0,05213196 0,06546424 ! platelet activation GO:0030168 37 23 0,000 0,05213196 0,06543009 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05213196 0,06539598 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05213196 0,0653619 ! cell-cell recognition GO:0009988 25 23 0,000 0,05213196 0,06532786 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05213196 0,06529385 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05213196 0,06525988 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,05213196 0,06522594 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05213196 0,06519204 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05213196 0,06515818 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05433674 0,06787861 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05433674 0,06784338 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05433674 0,06780819 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05433674 0,06777304 ! vesicle docking GO:0048278 47 24 0,000 0,05433674 0,06773793 ! spinal cord development GO:0021510 47 24 0,000 0,05433674 0,06770285 ! vacuole organization GO:0007033 43 24 0,000 0,05433674 0,06766781 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05433674 0,0676328 ! digestive system process GO:0022600 39 24 0,000 0,05433674 0,06759783 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05433674 0,06756289 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05433674 0,067528 ! regulation of behavior GO:0050795 43 24 0,000 0,05433674 0,06749313 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05433674 0,06745831 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05433674 0,06742352 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05433674 0,06738876 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05433674 0,06735404 ! pallium development GO:0021543 49 24 0,000 0,05433674 0,06731936 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05433674 0,06728471 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05433674 0,0672501 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05433674 0,06721553 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05433674 0,06718099 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05433674 0,06714648 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05433674 0,06711201 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05433674 0,06707758 ! regulation of amine transport GO:0051952 40 24 0,000 0,05433674 0,06704318 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05653647 0,06972155 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05653647 0,06968583 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05653647 0,06965015 ! phototransduction GO:0007602 33 25 0,000 0,05653647 0,06961451 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05653647 0,0695789 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,05653647 0,06954333 ! sperm motility GO:0030317 31 25 0,000 0,05653647 0,06950779 ! chromosome condensation GO:0030261 45 25 0,000 0,05653647 0,06947229 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05653647 0,06943683 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05653647 0,0694014 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05653647 0,06936601 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05653647 0,06933066 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,05653647 0,06929534 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05653647 0,06926005 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,05653647 0,06922481 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05653647 0,0691896 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05653647 0,06915442 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05653647 0,06911928 ! telomere organization GO:0032200 43 25 0,000 0,05653647 0,06908418 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05653647 0,06904911 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05653647 0,06901408 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05873115 0,07165677 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05873115 0,07162045 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05873115 0,07158417 ! initiation of viral infection GO:0019059 57 26 0,000 0,05873115 0,07154793 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05873115 0,07151172 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05873115 0,07147555 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05873115 0,07143941 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05873115 0,07140331 ! molting cycle process GO:0022404 50 26 0,000 0,05873115 0,07136725 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05873115 0,07133123 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05873115 0,07129524 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,05873115 0,07125928 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05873115 0,07122337 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,05873115 0,07118748 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,05873115 0,07115164 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05873115 0,07111583 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05873115 0,07108006 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05873115 0,07104432 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05873115 0,07100862 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05873115 0,07097296 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05873115 0,07093733 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05873115 0,07090173 ! neuron fate commitment GO:0048663 48 27 0,000 0,06092081 0,07350825 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,06092081 0,07347141 ! iron ion transport GO:0006826 59 27 0,000 0,06092081 0,0734346 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06092081 0,07339783 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06092081 0,07336109 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06092081 0,07332439 ! fat cell differentiation GO:0045444 50 27 0,000 0,06092081 0,07328773 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06092081 0,0732511 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06092081 0,07321452 ! autophagy GO:0006914 41 27 0,000 0,06092081 0,07317796 ! male gonad development GO:0008584 44 27 0,000 0,06092081 0,07314145 ! response to toxin GO:0009636 47 27 0,000 0,06092081 0,07310497 ! primary neural tube formation GO:0014020 51 27 0,000 0,06092081 0,07306852 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06092081 0,07303212 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06092081 0,07299575 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06092081 0,07295941 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06092081 0,07292311 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06092081 0,07288685 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06092081 0,07285063 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06310544 0,07542557 ! circadian rhythm GO:0007623 50 28 0,000 0,06310544 0,07538812 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06310544 0,07535071 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,06310544 0,07531333 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06310544 0,075276 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06310544 0,07523869 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06310544 0,07520143 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06310544 0,0751642 ! synaptogenesis GO:0007416 42 28 0,000 0,06310544 0,07512701 ! lipid oxidation GO:0034440 43 28 0,000 0,06310544 0,07508985 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06310544 0,07505273 ! translational initiation GO:0006413 65 29 0,000 0,06528506 0,07760665 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06528506 0,07756832 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06528506 0,07753003 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06528506 0,07749179 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06528506 0,07745358 ! catechol metabolic process GO:0009712 54 29 0,000 0,06528506 0,0774154 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06528506 0,07737727 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06528506 0,07733917 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06528506 0,07730111 ! cell fate determination GO:0001709 60 29 0,000 0,06528506 0,07726308 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06528506 0,0772251 ! detection of light stimulus GO:0009583 38 29 0,000 0,06528506 0,07718715 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,06528506 0,07714924 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06528506 0,07711137 ! tissue homeostasis GO:0001894 48 29 0,000 0,06528506 0,07707353 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,06745968 0,07960176 ! zinc ion transport GO:0006829 45 30 0,000 0,06745968 0,07956274 ! membrane docking GO:0022406 61 30 0,000 0,06745968 0,07952376 ! cell junction assembly GO:0034329 78 30 0,000 0,06745968 0,07948482 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06745968 0,07944591 ! acute-phase response GO:0006953 49 30 0,000 0,06745968 0,07940704 ! myofibril assembly GO:0030239 47 30 0,000 0,06745968 0,07936821 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06745968 0,07932942 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06745968 0,07929067 ! phospholipid transport GO:0015914 51 30 0,000 0,06745968 0,07925195 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06745968 0,07921327 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06745968 0,07917463 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06745968 0,07913603 ! eye morphogenesis GO:0048592 60 30 0,000 0,06745968 0,07909746 ! response to heat GO:0009408 50 30 0,000 0,06745968 0,07905893 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06962932 0,0815619 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06962932 0,08152221 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06962932 0,08148256 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06962932 0,08144294 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06962932 0,08140337 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06962932 0,08136383 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06962932 0,08132434 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06962932 0,08128488 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06962932 0,08124546 ! ovulation cycle process GO:0022602 49 31 0,000 0,06962932 0,08120608 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06962932 0,08116673 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,06962932 0,08112743 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06962932 0,08108816 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06962932 0,08104893 ! natural killer cell activation GO:0030101 45 31 0,000 0,06962932 0,08100974 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06962932 0,08097058 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06962932 0,08093147 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06962932 0,08089239 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06962932 0,08085335 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06962932 0,08081434 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07179398 0,08328655 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07179398 0,08324641 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07179398 0,08320631 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07179398 0,08316625 ! cholesterol transport GO:0030301 56 32 0,000 0,07179398 0,08312623 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07179398 0,08308625 ! spliceosome assembly GO:0000245 67 32 0,000 0,07179398 0,0830463 ! spindle organization GO:0007051 46 32 0,000 0,07179398 0,08300639 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07179398 0,08296653 ! metanephros development GO:0001656 74 32 0,000 0,07179398 0,0829267 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07179398 0,0828869 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07179398 0,08284715 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07179398 0,08280743 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,07179398 0,08276776 ! muscle cell development GO:0055001 49 32 0,000 0,07179398 0,08272812 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07179398 0,08268851 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07179398 0,08264895 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07179398 0,08260942 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07179398 0,08256994 ! ovulation cycle GO:0042698 51 32 0,000 0,07179398 0,08253049 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07179398 0,08249107 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07179398 0,0824517 ! gene silencing GO:0016458 65 32 0,000 0,07179398 0,08241236 ! post-embryonic development GO:0009791 69 33 0,000 0,07395367 0,08485099 ! protein targeting to membrane GO:0006612 68 33 0,000 0,07395367 0,08481055 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,07395367 0,08477014 ! ceramide metabolic process GO:0006672 64 33 0,000 0,07395367 0,08472978 ! cell fate specification GO:0001708 52 33 0,000 0,07395367 0,08468945 ! sterol transport GO:0015918 57 33 0,000 0,07395367 0,08464916 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,07395367 0,08460891 ! adult locomotory behavior GO:0008344 59 33 0,000 0,07395367 0,08456869 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,07395367 0,08452852 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,07395367 0,08448838 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07610841 0,0869088 ! glial cell differentiation GO:0010001 63 34 0,000 0,07610841 0,08686757 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07610841 0,08682638 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07610841 0,08678523 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07610841 0,08674412 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07610841 0,08670305 ! mismatch repair GO:0006298 46 34 0,000 0,07610841 0,08666202 ! spermatid development GO:0007286 63 34 0,000 0,07610841 0,08662102 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07610841 0,08658007 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07610841 0,08653915 ! placenta development GO:0001890 53 34 0,000 0,07610841 0,08649827 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,07825821 0,08889955 ! odontogenesis GO:0042476 66 35 0,000 0,07825821 0,0888576 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,07825821 0,08881569 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,07825821 0,08877381 ! cytokine production GO:0001816 59 35 0,000 0,07825821 0,08873198 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,07825821 0,08869018 ! neural tube formation GO:0001841 67 35 0,000 0,07825821 0,08864843 ! vesicle localization GO:0051648 64 35 0,000 0,07825821 0,08860671 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,08040308 0,09099238 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,08040308 0,09094961 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,08040308 0,09090687 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,08040308 0,09086417 ! cell junction organization GO:0034330 86 36 0,000 0,08040308 0,09082151 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,08040308 0,09077889 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,08040308 0,09073631 ! positive regulation of cell development GO:0010720 80 36 0,000 0,08040308 0,09069377 ! regulation of proteolysis GO:0030162 72 36 0,000 0,08040308 0,09065127 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,08040308 0,09060881 ! aerobic respiration GO:0009060 55 36 0,000 0,08040308 0,09056639 ! embryonic organ development GO:0048568 57 36 0,000 0,08040308 0,09052401 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,08040308 0,09048167 ! RNA export from nucleus GO:0006405 56 37 0,000 0,08254303 0,09284644 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,08254303 0,09280305 ! meiosis I GO:0007127 65 37 0,000 0,08254303 0,0927597 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,08254303 0,0927164 ! sister chromatid segregation GO:0000819 58 37 0,000 0,08254303 0,09267313 ! actomyosin structure organization GO:0031032 62 37 0,000 0,08254303 0,09262991 ! organic anion transport GO:0015711 68 37 0,000 0,08254303 0,09258673 ! tissue remodeling GO:0048771 76 37 0,000 0,08254303 0,09254358 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,08254303 0,09250048 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,08254303 0,09245741 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,08254303 0,09241439 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,08254303 0,09237141 ! spermatid differentiation GO:0048515 66 37 0,000 0,08254303 0,09232846 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,08467807 0,0946726 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,08467807 0,09462863 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,08467807 0,09458469 ! nucleus organization GO:0006997 67 38 0,000 0,08467807 0,0945408 ! lipid homeostasis GO:0055088 67 38 0,000 0,08467807 0,09449695 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,08467807 0,09445314 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,08467807 0,09440937 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,08467807 0,09436565 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,08467807 0,09432196 ! mRNA catabolic process GO:0006402 71 39 0,000 0,08680821 0,09664995 ! learning GO:0007612 77 39 0,000 0,08680821 0,09660525 ! organic ether metabolic process GO:0018904 55 39 0,000 0,08680821 0,09656059 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,08680821 0,09651597 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08680821 0,09647139 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,08680821 0,09642685 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,08680821 0,09638235 ! RNA modification GO:0009451 57 39 0,000 0,08680821 0,09633789 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,08680821 0,09629348 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08893346 0,09860549 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08893346 0,09856007 ! feeding behavior GO:0007631 59 40 0,000 0,08893346 0,09851469 ! negative regulation of binding GO:0051100 72 40 0,000 0,08893346 0,09846936 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08893346 0,09842406 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08893346 0,09837881 ! maintenance of protein location GO:0045185 91 40 0,000 0,08893346 0,0983336 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,09105384 0,10063186 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,09105384 0,10058565 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,09105384 0,10053949 ! gliogenesis GO:0042063 88 41 0,000 0,09105384 0,10049337 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,09105384 0,10044729 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,09105384 0,10040126 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,09316936 0,10268689 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,09316936 0,10263987 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,09316936 0,1025929 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,09316936 0,10254596 ! neuron migration GO:0001764 79 42 0,000 0,09316936 0,10249908 ! regulation of protein secretion GO:0050708 71 42 0,000 0,09316936 0,10245223 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,09316936 0,10240543 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,09528002 0,1046775 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,09528002 0,10462973 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,09528002 0,10458199 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,09528002 0,1045343 ! neural tube development GO:0021915 77 43 0,000 0,09528002 0,10448666 ! striated muscle contraction GO:0006941 77 43 0,000 0,09528002 0,10443906 ! phagocytosis GO:0006909 90 43 0,000 0,09528002 0,1043915 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09528002 0,10434398 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09738584 0,10660161 ! male sex differentiation GO:0046661 76 44 0,000 0,09738584 0,10655313 ! biopolymer methylation GO:0043414 84 44 0,000 0,09738584 0,1065047 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,09738584 0,10645631 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09738584 0,10640796 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09738584 0,10635966 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09948683 0,10860495 ! glycolysis GO:0006096 65 45 0,000 0,09948683 0,10855569 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,09948683 0,10850649 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09948683 0,10845732 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09948683 0,1084082 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09948683 0,10835912 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09948683 0,10831009 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09948683 0,10826111 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09948683 0,10821216 ! cell growth GO:0016049 84 45 0,000 0,09948683 0,10816327 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,10158299 0,11039236 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,10158299 0,11034252 ! pigmentation GO:0043473 100 46 0,000 0,10158299 0,11029273 ! positive regulation of defense response GO:0031349 76 47 0,000 0,10367435 0,11251262 ! response to calcium ion GO:0051592 81 47 0,000 0,10367435 0,1124619 ! endosome transport GO:0016197 108 47 0,000 0,10367435 0,11241122 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,10367435 0,11236058 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,10367435 0,11230999 ! JNK cascade GO:0007254 91 47 0,000 0,10367435 0,11225945 ! methylation GO:0032259 90 47 0,000 0,10367435 0,11220895 ! protein homooligomerization GO:0051260 76 47 0,000 0,10367435 0,11215849 ! Notch signaling pathway GO:0007219 96 48 0,000 0,10576091 0,11436438 ! cellular component disassembly GO:0022411 86 48 0,000 0,10576091 0,114313 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,10576091 0,11426167 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,10576091 0,11421039 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,10576091 0,11415915 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,10576091 0,11410796 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10784268 0,11630188 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,10784268 0,11624977 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,10784268 0,11619771 ! regulation of ion transport GO:0043269 77 49 0,000 0,10784268 0,1161457 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10784268 0,11609373 ! peptide metabolic process GO:0006518 76 49 0,000 0,10784268 0,11604181 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10784268 0,11598993 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10784268 0,11593811 ! endocrine system development GO:0035270 104 49 0,000 0,10784268 0,11588633 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10784268 0,11583459 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10784268 0,1157829 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,10991967 0,11796018 ! neuromuscular process GO:0050905 99 50 0,000 0,10991967 0,11790759 ! inner ear development GO:0048839 79 50 0,000 0,10991967 0,11785505 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,10991967 0,11780255 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,10991967 0,1177501 ! viral infectious cycle GO:0019058 99 51 0,000 0,1119919 0,11991656 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,1119919 0,11986321 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,1119919 0,11980992 ! chromatin remodeling GO:0006338 109 51 0,000 0,1119919 0,11975667 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,1119919 0,11970347 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,1119919 0,11965031 ! vesicle organization GO:0016050 107 51 0,000 0,1119919 0,11959721 ! regulation of cell shape GO:0008360 125 51 0,000 0,1119919 0,11954415 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,1119919 0,11949113 ! membrane fusion GO:0006944 110 52 0,000 0,11405937 0,1216431 ! amino acid activation GO:0043038 92 52 0,000 0,11405937 0,12158921 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,11612209 0,12373328 ! RNA catabolic process GO:0006401 93 53 0,000 0,11612209 0,12367851 ! regulation of translational initiation GO:0006446 82 53 0,000 0,11612209 0,12362379 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,11612209 0,12356911 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,11612209 0,12351448 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,11612209 0,1234599 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,11818008 0,12559244 ! cell recognition GO:0008037 85 54 0,000 0,11818008 0,12553699 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11818008 0,12548159 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11818008 0,12542624 ! chloride transport GO:0006821 90 55 0,000 0,12023335 0,12754914 ! glucose catabolic process GO:0006007 82 55 0,000 0,12023335 0,12749292 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,12023335 0,12743676 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,12023335 0,12738065 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,12023335 0,12732458 ! RNA elongation GO:0006354 79 55 0,000 0,12023335 0,12726856 ! nuclear export GO:0051168 97 55 0,000 0,12023335 0,1272126 ! regulation of actin filament length GO:0030832 105 56 0,000 0,12228191 0,1293232 ! sensory perception of smell GO:0007608 80 56 0,000 0,12228191 0,12926637 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,12228191 0,1292096 ! proton transport GO:0015992 94 56 0,000 0,12228191 0,12915288 ! maintenance of location GO:0051235 118 57 0,000 0,12432576 0,13125396 ! hydrogen transport GO:0006818 97 58 0,000 0,12636492 0,13334825 ! regulation of endocytosis GO:0030100 91 58 0,000 0,12636492 0,13328979 ! adult behavior GO:0030534 99 58 0,000 0,12636492 0,13323138 ! regulation of cellular component size GO:0032535 109 59 0,000 0,1283994 0,13531711 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1283994 0,13525786 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,1283994 0,13519867 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,1283994 0,13513953 ! establishment of organelle localization GO:0051656 109 59 0,000 0,1283994 0,13508044 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,13042921 0,13715589 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,13042921 0,13709598 ! camera-type eye development GO:0043010 116 60 0,000 0,13042921 0,13703611 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,13042921 0,13697629 ! kidney development GO:0001822 122 60 0,000 0,13042921 0,13691653 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,13245436 0,13898177 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,13245436 0,13892119 ! tRNA processing GO:0008033 89 61 0,000 0,13245436 0,13886065 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,13245436 0,13880017 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,13447487 0,14085613 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,13447487 0,14079483 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,13649073 0,14284328 ! detection of external stimulus GO:0009581 91 63 0,000 0,13649073 0,14278117 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,13649073 0,14271912 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,13850196 0,14475922 ! cell redox homeostasis GO:0045454 102 64 0,000 0,13850196 0,14469636 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,13850196 0,14463356 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,13850196 0,14457081 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,14050858 0,14660175 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,14050858 0,14653821 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,14050858 0,14647472 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,14050858 0,14641128 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,14251059 0,14843311 ! actin filament organization GO:0007015 148 66 0,000 0,14251059 0,14836888 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,14251059 0,14830471 ! extracellular matrix organization GO:0030198 133 66 0,000 0,14251059 0,14824059 ! secondary metabolic process GO:0019748 116 66 0,000 0,14251059 0,14817653 ! cell projection assembly GO:0030031 120 66 0,000 0,14251059 0,14811252 ! chromosome segregation GO:0007059 113 67 0,000 0,144508 0,1501236 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,144508 0,15005881 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,144508 0,14999407 ! hexose catabolic process GO:0019320 104 67 0,000 0,144508 0,14992939 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,144508 0,14986477 ! amino acid transport GO:0006865 125 68 0,000 0,14650083 0,151866 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,14650083 0,1518006 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,14650083 0,15173525 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,14650083 0,15166996 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14848908 0,15366225 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14848908 0,15359619 ! urogenital system development GO:0001655 137 69 0,000 0,14848908 0,15353018 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14848908 0,15346423 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14848908 0,15339834 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14848908 0,1533325 ! appendage morphogenesis GO:0035107 135 70 0,000 0,15047277 0,15531423 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,15245189 0,15728956 ! appendage development GO:0048736 136 71 0,000 0,15245189 0,15722214 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 137 71 0,000 0,15245189 0,15715478 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,15442648 0,1591221 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,15442648 0,15905399 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,15442648 0,15898593 ! learning or memory GO:0007611 147 73 0,000 0,15639653 0,16094527 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,15639653 0,16087646 ! fertilization GO:0009566 90 73 0,000 0,15639653 0,16080771 ! transition metal ion transport GO:0000041 126 74 0,000 0,15836205 0,16275912 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15836205 0,16268963 ! exocytosis GO:0006887 133 74 0,000 0,15836205 0,16262019 ! eye development GO:0001654 143 74 0,000 0,15836205 0,16255081 ! organelle localization GO:0051640 136 74 0,000 0,15836205 0,16248149 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,16032307 0,1644234 ! rhythmic process GO:0048511 128 75 0,000 0,16032307 0,16435334 ! defense response to bacterium GO:0042742 89 76 0,000 0,16227957 0,16628818 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,16227957 0,16621739 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,16423159 0,16814519 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,16423159 0,16807367 ! blood coagulation GO:0007596 146 78 0,000 0,16617912 0,16999445 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,16617912 0,16992221 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,16617912 0,16985002 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,16812217 0,17176303 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,16812217 0,17169013 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,17006076 0,17359618 ! response to metal ion GO:0010038 140 80 0,000 0,17006076 0,17352256 ! muscle cell differentiation GO:0042692 159 80 0,000 0,17006076 0,173449 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,17006076 0,17337551 ! inorganic anion transport GO:0015698 138 80 0,000 0,17006076 0,17330207 ! digestion GO:0007586 112 81 0,000 0,1719949 0,17519887 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,1719949 0,17512473 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,1719949 0,17505065 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,1739246 0,17693978 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,1739246 0,176865 ! regulation of lyase activity GO:0051339 160 83 0,000 0,17584986 0,17874726 ! hemostasis GO:0007599 158 84 0,000 0,1777707 0,18062344 ! regulation of ligase activity GO:0051340 142 84 0,000 0,1777707 0,1805472 ! response to unfolded protein GO:0006986 131 85 0,000 0,17968713 0,18241655 ! nucleosome assembly GO:0006334 122 85 0,000 0,17968713 0,18233962 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17968713 0,18226275 ! amine biosynthetic process GO:0009309 138 86 0,000 0,18159915 0,18412455 ! response to inorganic substance GO:0010035 153 86 0,000 0,18159915 0,18404699 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,18159915 0,1839695 ! chromatin assembly GO:0031497 124 86 0,000 0,18159915 0,18389207 ! alcohol catabolic process GO:0046164 130 86 0,000 0,18159915 0,18381471 ! amine transport GO:0015837 155 86 0,000 0,18159915 0,18373741 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,18350678 0,18558946 ! cellular respiration GO:0045333 135 88 0,000 0,18541003 0,18743552 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,18541003 0,1873568 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,18541003 0,18727814 ! cellular defense response GO:0006968 114 89 0,000 0,18730891 0,18911676 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,18730891 0,18903743 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,18920342 0,19086936 ! sterol metabolic process GO:0016125 152 91 0,000 0,19109358 0,19269537 ! response to protein stimulus GO:0051789 149 91 0,000 0,19109358 0,19261464 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,19109358 0,19253398 ! regulation of defense response GO:0031347 149 92 0,000 0,19297939 0,19435262 ! nucleosome organization GO:0034728 138 92 0,000 0,19297939 0,1942713 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,19297939 0,19419005 ! vitamin metabolic process GO:0006766 139 92 0,000 0,19297939 0,19410887 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,19486087 0,19591945 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,19486087 0,19583762 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,19673803 0,19764162 ! transcription initiation GO:0006352 153 94 0,000 0,19673803 0,19755914 ! forebrain development GO:0030900 188 95 0,000 0,19861087 0,19935659 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,20047941 0,20114823 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,20047941 0,20106438 ! detection of stimulus GO:0051606 151 96 0,000 0,20047941 0,2009806 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,20234365 0,20276502 ! response to virus GO:0009615 160 98 0,000 0,20420361 0,20454366 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,20420361 0,20445854 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,20420361 0,20437349 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,20605929 0,20614497 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,20605929 0,20605929