pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6604-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 2,028E-08 4,88E-05 ! positive regulation of phosphorylation GO:0042327 129 79 5,000 2,063E-07 2,482E-04 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 5,000 2,396E-07 1,922E-04 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 2,59E-07 1,558E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 3,271E-07 1,574E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 6,785E-07 2,721E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 9,808E-07 3,371E-04 ! regulation of granule cell precursor proliferation GO:0021936 13 7 2,000 1,088E-06 3,273E-04 GO:0021940|positive regulation of granule cell precursor proliferation, ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 1,088E-06 2,91E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,373E-06 3,304E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,373E-06 3,003E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 1,608E-06 3,224E-04 ! ER overload response GO:0006983 12 8 2,000 1,737E-06 3,215E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,737E-06 2,986E-04 ! activation of MAPK activity GO:0000187 115 67 4,000 2,447E-06 3,924E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 2,447E-06 3,679E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 2,6E-06 3,68E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 3,706E-06 4,953E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 5,083E-06 6,437E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 5,083E-06 6,115E-04 GO:0010829|negative regulation of glucose transport, ! cellular response to insulin stimulus GO:0032869 82 37 3,000 5,905E-06 6,766E-04 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 6,762E-06 7,395E-04 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 1,114E-05 1,165E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,389E-05 1,392E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 1,427E-05 1,374E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 1,427E-05 1,321E-03 ! activation of MAPKK activity GO:0000186 35 16 2,000 1,705E-05 1,52E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,066E-05 1,775E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 2,066E-05 1,714E-03 ! response to UV GO:0009411 104 53 3,000 2,518E-05 2,02E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,364E-05 2,611E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 3,364E-05 2,529E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,44E-05 2,508E-03 ! regulation of glucose import GO:0046324 29 20 2,000 3,44E-05 2,434E-03 GO:0010827|regulation of glucose transport, ! inactivation of MAPK activity GO:0000188 39 21 2,000 4,004E-05 2,752E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 4,004E-05 2,676E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 4,004E-05 2,604E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 4,122E-05 2,61E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 4,401E-05 2,715E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 4,625E-05 2,782E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 5,307E-05 3,114E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 5,319E-05 3,047E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 6,051E-05 3,386E-03 ! regulation of behavior GO:0050795 43 24 2,000 6,051E-05 3,309E-03 ! protein tetramerization GO:0051262 52 24 2,000 6,051E-05 3,235E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 6,37E-05 3,332E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 6,752E-05 3,456E-03 ! myelination GO:0042552 45 25 2,000 6,86E-05 3,439E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 6,86E-05 3,368E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 6,86E-05 3,301E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 8,447E-05 3,985E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 8,447E-05 3,908E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 8,684E-05 3,942E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 9,704E-05 4,324E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 9,704E-05 4,245E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 1,000 9,992E-05 4,293E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 9,992E-05 4,218E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 9,992E-05 4,145E-03 ! muscle cell migration GO:0014812 8 5 1,000 9,992E-05 4,075E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 9,992E-05 4,007E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 9,992E-05 3,941E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,08E-04 4,19E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 1,197E-04 4,572E-03 GO:0008366|axon ensheathment, ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,402E-04 5,269E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 1,456E-04 5,388E-03 ! male sex determination GO:0030238 15 6 1,000 1,496E-04 5,453E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,496E-04 5,371E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,496E-04 5,292E-03 ! negative regulation of transport GO:0051051 153 84 3,000 1,539E-04 5,365E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,598E-04 5,491E-03 GO:0060326|cell chemotaxis, ! positive regulation of protein modification process GO:0031401 136 88 3,000 1,841E-04 6,24E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,09E-04 6,983E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,09E-04 6,887E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,09E-04 6,794E-03 ! fibrinolysis GO:0042730 10 7 1,000 2,09E-04 6,704E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,09E-04 6,616E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,09E-04 6,53E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,09E-04 6,446E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,09E-04 6,364E-03 ! positive regulation of ATPase activity GO:0032781 11 7 1,000 2,09E-04 6,285E-03 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 1,000 2,09E-04 6,207E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,472E-04 7,252E-03 ! regulation of action potential in neuron GO:0019228 73 39 2,000 2,639E-04 7,65E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,78E-04 7,964E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 2,78E-04 7,87E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,78E-04 7,779E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,78E-04 7,689E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,78E-04 7,602E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 1,000 2,78E-04 7,517E-03 ! interphase GO:0051325 213 98 3,000 2,784E-04 7,443E-03 ! gliogenesis GO:0042063 88 41 2,000 3,064E-04 8,101E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 3,531E-04 9,234E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,567E-04 9,229E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,567E-04 9,131E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 3,567E-04 9,035E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 21 9 1,000 3,567E-04 8,941E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 3,567E-04 8,849E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,567E-04 8,758E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,567E-04 8,67E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,567E-04 8,583E-03 ! induction of an organ GO:0001759 14 9 1,000 3,567E-04 8,498E-03 ! leukocyte migration GO:0050900 68 45 2,000 4,041E-04 9,533E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 4,313E-04 0,01007568 ! negative regulation of cell migration GO:0030336 115 46 2,000 4,313E-04 9,979E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 4,45E-04 0,01019702 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,45E-04 0,01010082 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,45E-04 0,01000642 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 4,45E-04 9,914E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 4,45E-04 9,823E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 4,45E-04 9,734E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,45E-04 9,646E-03 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 4,45E-04 9,56E-03 ! positive regulation of defense response GO:0031349 76 47 2,000 4,597E-04 9,788E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 4,892E-04 0,01032472 ! regulation of inflammatory response GO:0050727 75 48 2,000 4,892E-04 0,01023494 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 4,892E-04 0,0101467 ! regulation of action potential GO:0001508 95 49 2,000 5,199E-04 0,01069139 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 5,199E-04 0,01060079 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,428E-04 0,01097395 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,428E-04 0,0108825 ! developmental induction GO:0031128 19 11 1,000 5,428E-04 0,01079256 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 5,428E-04 0,0107041 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 5,85E-04 0,01144232 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 2,000 6,193E-04 0,01201722 ! regulation of muscle contraction GO:0006937 81 52 2,000 6,193E-04 0,01192108 ! cartilage development GO:0051216 90 52 2,000 6,193E-04 0,01182647 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 6,5E-04 0,01231359 ! virus-host interaction GO:0019048 29 12 1,000 6,5E-04 0,01221739 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,5E-04 0,01212268 ! negative regulation of endothelial cell migration GO:0010596 25 12 1,000 6,5E-04 0,01202943 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 6,5E-04 0,0119376 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 6,5E-04 0,01184716 ! negative regulation of cell motion GO:0051271 134 55 2,000 7,302E-04 0,01320874 ! cell-cell junction assembly GO:0007043 27 13 1,000 7,666E-04 0,01376359 ! response to X-ray GO:0010165 25 13 1,000 7,666E-04 0,01366164 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,666E-04 0,01356118 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 7,666E-04 0,0134622 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,666E-04 0,01336464 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 7,666E-04 0,01326849 ! nucleotide-excision repair GO:0006289 83 56 2,000 7,697E-04 0,01322808 ! regulation of DNA replication GO:0006275 101 56 2,000 7,697E-04 0,01313427 ! response to gamma radiation GO:0010332 28 14 1,000 8,925E-04 0,01512142 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 8,925E-04 0,01501568 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,925E-04 0,0149114 ! regulation of heart contraction GO:0008016 110 60 2,000 9,415E-04 0,01562227 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 9,415E-04 0,01551527 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,028E-03 0,01681936 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,028E-03 0,01670571 ! regulation of ATPase activity GO:0043462 21 15 1,000 1,028E-03 0,01659359 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,172E-03 0,0187986 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,172E-03 0,01867411 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 1,172E-03 0,01855125 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,172E-03 0,01843 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,172E-03 0,01831033 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,172E-03 0,0181922 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,297E-03 0,02000297 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 1,325E-03 0,02031296 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,325E-03 0,02018439 ! negative regulation of cell size GO:0045792 134 69 2,000 1,412E-03 0,02136611 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,488E-03 0,0223771 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,488E-03 0,02223812 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,488E-03 0,02210084 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 1,66E-03 0,02449851 ! lipid phosphorylation GO:0046834 35 19 1,000 1,66E-03 0,02434913 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 1,66E-03 0,02420156 ! mitotic chromosome condensation GO:0007076 34 19 1,000 1,66E-03 0,02405577 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,66E-03 0,02391172 ! neuromuscular junction development GO:0007528 34 19 1,000 1,66E-03 0,02376939 ! plasma membrane fusion GO:0045026 28 19 1,000 1,66E-03 0,02362874 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,66E-03 0,02348975 ! G1 phase GO:0051318 40 19 1,000 1,66E-03 0,02335238 ! cell-cell junction organization GO:0045216 35 19 1,000 1,66E-03 0,02321661 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,84E-03 0,02559397 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,84E-03 0,02544688 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,84E-03 0,02530147 ! cellular response to starvation GO:0009267 33 20 1,000 1,84E-03 0,02515771 ! peptidyl-serine modification GO:0018209 43 20 1,000 1,84E-03 0,02501558 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,84E-03 0,02487504 ! negative regulation of translation GO:0017148 29 20 1,000 1,84E-03 0,02473607 ! negative regulation of coagulation GO:0050819 29 20 1,000 1,84E-03 0,02459865 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,84E-03 0,02446275 ! blood coagulation GO:0007596 146 78 2,000 2,008E-03 0,02654834 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 2,000 2,008E-03 0,02640326 ! cell aging GO:0007569 44 21 1,000 2,03E-03 0,02654183 ! activation of protein kinase activity GO:0032147 147 79 2,000 2,083E-03 0,02708653 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,228E-03 0,02882225 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,228E-03 0,02866812 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,228E-03 0,02851563 ! activation of JUN kinase activity GO:0007257 42 22 1,000 2,228E-03 0,02836475 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,228E-03 0,02821546 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,435E-03 0,03067719 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 2,435E-03 0,03051741 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,435E-03 0,03035929 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 1,000 2,435E-03 0,0302028 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,435E-03 0,03004791 ! platelet activation GO:0030168 37 23 1,000 2,435E-03 0,02989461 ! hemostasis GO:0007599 158 84 2,000 2,481E-03 0,03029941 ! negative regulation of growth GO:0045926 155 84 2,000 2,481E-03 0,03014639 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,651E-03 0,03205415 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,651E-03 0,03189388 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,651E-03 0,0317352 ! regulation of protein transport GO:0051223 154 87 2,000 2,741E-03 0,0326457 GO:0070201|regulation of establishment of protein localization, ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,876E-03 0,03408423 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,876E-03 0,03391715 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,876E-03 0,0337517 ! chromosome condensation GO:0030261 45 25 1,000 2,876E-03 0,03358786 ! response to starvation GO:0042594 42 25 1,000 2,876E-03 0,0334256 ! negative regulation of cell development GO:0010721 73 25 1,000 2,876E-03 0,0332649 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,876E-03 0,03310574 ! regulation of blood coagulation GO:0030193 40 25 1,000 2,876E-03 0,03294809 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,876E-03 0,03279194 ! regulation of cell adhesion GO:0030155 212 89 2,000 2,923E-03 0,03317457 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 3,109E-03 0,03511821 ! positive regulation of nuclear division GO:0051785 40 26 1,000 3,109E-03 0,0349541 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 3,109E-03 0,03479152 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 3,109E-03 0,03463045 ! regulation of defense response GO:0031347 149 92 2,000 3,21E-03 0,03559384 ! regulation of membrane potential GO:0042391 164 93 2,000 3,31E-03 0,03652778 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,351E-03 0,03681222 ! base-excision repair GO:0006284 41 27 1,000 3,351E-03 0,0366449 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,351E-03 0,03647908 ! dendrite development GO:0016358 59 28 1,000 3,601E-03 0,03902731 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,601E-03 0,0388523 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 3,601E-03 0,03867885 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 3,726E-03 0,03984486 ! regulation of protein localization GO:0032880 176 97 2,000 3,726E-03 0,03966856 ! regulation of pH GO:0006885 43 29 1,000 3,86E-03 0,04091013 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 3,86E-03 0,0407307 ! regulation of coagulation GO:0050818 46 29 1,000 3,86E-03 0,04055284 ! cell cycle arrest GO:0007050 213 100 2,000 4,059E-03 0,04245596 ! cell junction assembly GO:0034329 78 30 1,000 4,127E-03 0,04298422 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 4,127E-03 0,04279895 ! regulation of B cell activation GO:0050864 50 30 1,000 4,127E-03 0,04261526 ! response to ionizing radiation GO:0010212 65 32 1,000 4,686E-03 0,04818375 ! peripheral nervous system development GO:0007422 64 32 1,000 4,686E-03 0,04797871 ! positive regulation of catabolic process GO:0009896 64 32 1,000 4,686E-03 0,04777541 ! DNA damage checkpoint GO:0000077 71 33 1,000 4,978E-03 0,05053847 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,978E-03 0,05032613 ! cell fate specification GO:0001708 52 33 1,000 4,978E-03 0,05011556 ! glial cell differentiation GO:0010001 63 34 1,000 5,278E-03 0,05291638 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 5,278E-03 0,05269681 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,587E-03 0,05554467 ! negative regulation of secretion GO:0051048 63 35 1,000 5,587E-03 0,05531609 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,587E-03 0,05508938 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,587E-03 0,05486453 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,587E-03 0,0546415 ! regulation of microtubule-based process GO:0032886 78 35 1,000 5,587E-03 0,05442028 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 5,903E-03 0,05727065 ! cell junction organization GO:0034330 86 36 1,000 5,903E-03 0,05704064 ! DNA integrity checkpoint GO:0031570 75 36 1,000 5,903E-03 0,05681248 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 5,903E-03 0,05658614 ! negative regulation of cell activation GO:0050866 65 36 1,000 5,903E-03 0,05636159 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 6,228E-03 0,05922425 ! sister chromatid segregation GO:0000819 58 37 1,000 6,228E-03 0,05899108 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 6,228E-03 0,05875975 ! glycogen metabolic process GO:0005977 61 37 1,000 6,228E-03 0,05853022 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,56E-03 0,0614145 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 6,56E-03 0,06117646 ! carbohydrate homeostasis GO:0033500 53 38 1,000 6,56E-03 0,06094026 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,56E-03 0,06070587 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 6,56E-03 0,06047329 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 6,9E-03 0,06336782 ! regulation of T cell proliferation GO:0042129 71 41 1,000 7,605E-03 0,06956916 ! T cell differentiation GO:0030217 81 41 1,000 7,605E-03 0,06930564 ! regulation of T cell differentiation GO:0045580 70 41 1,000 7,605E-03 0,06904411 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 7,968E-03 0,07207488 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 7,968E-03 0,07180494 ! regulation of protein secretion GO:0050708 71 42 1,000 7,968E-03 0,07153701 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 7,968E-03 0,07127107 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 8,34E-03 0,07431738 ! energy reserve metabolic process GO:0006112 74 43 1,000 8,34E-03 0,07404315 ! double-strand break repair GO:0006302 81 44 1,000 8,719E-03 0,07712458 ! B cell differentiation GO:0030183 107 44 1,000 8,719E-03 0,07684207 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 9,106E-03 0,07995758 ! cell growth GO:0016049 84 45 1,000 9,106E-03 0,07966682 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 9,5E-03 0,08281536 ! positive regulation of protein transport GO:0051222 72 46 1,000 9,5E-03 0,08251639 ! JNK cascade GO:0007254 91 47 1,000 9,902E-03 0,08569695 ! regulation of JNK cascade GO:0046328 94 47 1,000 9,902E-03 0,08538979 ! mitochondrial transport GO:0006839 82 48 1,000 0,01031105 0,0886014 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,01031105 0,08828609 ! activation of caspase activity GO:0006919 84 48 1,000 0,01031105 0,08797302 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01031105 0,08766216 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,0107277 0,09088324 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,0107277 0,09056435 ! peptide metabolic process GO:0006518 76 49 1,000 0,0107277 0,09024769 ! regulation of ossification GO:0030278 117 50 1,000 0,01115169 0,0934877 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01115169 0,09316309 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01115169 0,09284073 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,01158299 0,09609885 ! membrane fusion GO:0006944 110 52 1,000 0,01202153 0,09939453 ! positive regulation of growth GO:0045927 90 52 1,000 0,01202153 0,09905414 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,01202153 0,09871607 ! synapse organization GO:0050808 85 52 1,000 0,01202153 0,0983803 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01246728 0,10168229 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01292018 0,1050201 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01292018 0,10466649 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01338018 0,10802923 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01338018 0,10766793 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01338018 0,10730903 ! aging GO:0007568 103 55 1,000 0,01338018 0,10695253 ! heart morphogenesis GO:0003007 97 55 1,000 0,01338018 0,10659838 ! RNA elongation GO:0006354 79 55 1,000 0,01338018 0,10624657 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01384723 0,10959356 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01384723 0,10923424 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01432129 0,11260467 ! muscle fiber development GO:0048747 112 57 1,000 0,01432129 0,11223788 ! lipid modification GO:0030258 97 57 1,000 0,01432129 0,11187347 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01432129 0,11151142 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01432129 0,11115171 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01480231 0,1145156 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01480231 0,11414857 ! DNA catabolic process GO:0006308 86 59 1,000 0,01529023 0,1175345 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,01578502 0,12095143 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0158376 0,12096913 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0158376 0,12058632 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0158376 0,12020592 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0158376 0,11982792 ! neuron fate determination GO:0048664 7 5 0,000 0,0158376 0,11945228 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0158376 0,11907899 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0158376 0,11870803 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0158376 0,11833937 ! polyol transport GO:0015791 12 5 0,000 0,0158376 0,117973 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0158376 0,11760888 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0158376 0,11724701 ! response to superoxide GO:0000303 10 5 0,000 0,0158376 0,11688735 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0158376 0,1165299 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0158376 0,11617463 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0158376 0,11582151 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0158376 0,11547054 ! female meiosis GO:0007143 7 5 0,000 0,0158376 0,11512168 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0158376 0,11477493 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0158376 0,11443026 ! cobalt ion transport GO:0006824 11 5 0,000 0,0158376 0,11408766 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0158376 0,1137471 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0158376 0,11340856 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0158376 0,11307204 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0158376 0,11273751 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0158376 0,11240495 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0158376 0,11207435 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0158376 0,11174568 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0158376 0,11141894 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0158376 0,1110941 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0158376 0,11077116 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0158376 0,11045008 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0158376 0,11013086 ! negative chemotaxis GO:0050919 14 5 0,000 0,0158376 0,10981348 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0158376 0,10949792 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0158376 0,10918418 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0158376 0,10887222 ! behavioral response to pain GO:0048266 9 5 0,000 0,0158376 0,10856204 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0158376 0,10825363 ! Notch receptor processing GO:0007220 8 5 0,000 0,0158376 0,10794696 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0158376 0,10764203 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0158376 0,10733881 ! micturition GO:0060073 9 5 0,000 0,0158376 0,1070373 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0158376 0,10673747 ! copulation GO:0007620 9 5 0,000 0,0158376 0,10643932 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0158376 0,10614283 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0158376 0,10584799 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0158376 0,10555479 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0158376 0,1052632 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0158376 0,10497322 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0158376 0,10468483 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0158376 0,10439802 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0158376 0,10411278 ! grooming behavior GO:0007625 6 5 0,000 0,0158376 0,10382909 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0158376 0,10354695 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0158376 0,10326633 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0158376 0,10298724 ! response to protozoan GO:0001562 10 5 0,000 0,0158376 0,10270964 ! lymph vessel development GO:0001945 10 5 0,000 0,0158376 0,10243354 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0158376 0,10215892 ! endochondral ossification GO:0001958 16 5 0,000 0,0158376 0,10188577 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0158376 0,10161407 ! parathyroid gland development GO:0060017 13 5 0,000 0,0158376 0,10134382 ! anagen GO:0042640 6 5 0,000 0,0158376 0,10107501 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0158376 0,10080761 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0158376 0,10054163 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0158376 0,10027705 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0158376 0,10001385 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0158376 0,09975204 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0158376 0,09949159 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0158376 0,09923249 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0158376 0,09897475 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0158376 0,09871834 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0158376 0,09846325 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0158376 0,09820948 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0158376 0,09795701 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0158376 0,09770584 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0158376 0,09745595 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0158376 0,09720734 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0158376 0,09695999 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0158376 0,0967139 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0158376 0,09646906 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0158376 0,09622545 ! histidine catabolic process GO:0006548 6 5 0,000 0,0158376 0,09598307 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0158376 0,0957419 ! microvillus organization GO:0032528 7 5 0,000 0,0158376 0,09550195 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,0158376 0,09526319 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0158376 0,09502563 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0158376 0,09478925 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0158376 0,09455404 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0158376 0,09431999 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0158376 0,0940871 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0158376 0,09385536 ! polyol catabolic process GO:0046174 7 5 0,000 0,0158376 0,09362476 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0158376 0,09339529 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0158376 0,09316694 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0158376 0,0929397 ! mitochondrial fission GO:0000266 8 5 0,000 0,0158376 0,09271357 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0158376 0,09248854 ! mRNA transcription GO:0009299 9 5 0,000 0,0158376 0,09226459 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0158376 0,09204173 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0158376 0,09181995 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0158376 0,09159922 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0158376 0,09137956 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0158376 0,09116095 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0158376 0,09094338 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0158376 0,09072685 ! response to food GO:0032094 6 5 0,000 0,0158376 0,09051135 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0158376 0,09029687 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0158376 0,0900834 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0158376 0,08987094 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0158376 0,08965948 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0158376 0,08944901 ! forebrain neuron development GO:0021884 13 5 0,000 0,0158376 0,08923953 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0158376 0,08903102 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0158376 0,08882349 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0158376 0,08861692 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0158376 0,08841132 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0158376 0,08820666 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0158376 0,08800295 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0158376 0,08780018 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0158376 0,08759834 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0158376 0,08739743 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0158376 0,08719743 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0158376 0,08699835 ! basic amino acid transport GO:0015802 11 5 0,000 0,0158376 0,08680018 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0158376 0,0866029 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,0158376 0,08640652 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0158376 0,08621103 ! depyrimidination GO:0045008 10 5 0,000 0,0158376 0,08601643 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0158376 0,0858227 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0158376 0,08562984 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0158376 0,08543784 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0158376 0,08524671 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,0158376 0,08505642 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0158376 0,08486699 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0158376 0,08467839 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0158376 0,08449064 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0158376 0,08430371 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0158376 0,08411761 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0158376 0,08393233 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0158376 0,08374786 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0158376 0,0835642 ! response to arsenic GO:0046685 10 5 0,000 0,0158376 0,08338135 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0158376 0,0831993 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0158376 0,08301803 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0158376 0,08283756 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0158376 0,08265787 ! response to cadmium ion GO:0046686 7 5 0,000 0,0158376 0,08247896 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0158376 0,08230082 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0158376 0,08212344 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0158376 0,08194683 ! decidualization GO:0046697 11 5 0,000 0,0158376 0,08177098 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0158376 0,08159588 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0158376 0,08142153 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0158376 0,08124793 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0158376 0,08107506 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0158376 0,08090292 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0158376 0,08073152 ! neural tube patterning GO:0021532 7 5 0,000 0,0158376 0,08056084 ! embryonic cleavage GO:0040016 6 5 0,000 0,0158376 0,08039088 ! peroxisome fission GO:0016559 5 5 0,000 0,0158376 0,08022164 ! histone demethylation GO:0016577 10 5 0,000 0,0158376 0,0800531 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0158376 0,07988528 ! mitotic recombination GO:0006312 9 5 0,000 0,0158376 0,07971815 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0158376 0,07955173 ! metaphase plate congression GO:0051310 7 5 0,000 0,0158376 0,07938599 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0158376 0,07922095 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0158376 0,07905659 ! enteric nervous system development GO:0048484 8 5 0,000 0,0158376 0,07889291 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0158376 0,07872991 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0158376 0,07856758 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0158376 0,07840592 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0158376 0,07824492 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0158376 0,07808458 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0158376 0,0779249 ! plasminogen activation GO:0031639 5 5 0,000 0,0158376 0,07776587 ! B cell homeostasis GO:0001782 13 5 0,000 0,0158376 0,07760749 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0158376 0,07744975 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0158376 0,07729265 ! metaphase GO:0051323 8 5 0,000 0,0158376 0,07713619 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0158376 0,07698036 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0158376 0,07682516 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0158376 0,07667058 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0158376 0,07651662 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0158376 0,07636328 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0158376 0,07621055 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0158376 0,07605844 ! response to redox state GO:0051775 5 5 0,000 0,0158376 0,07590693 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0158376 0,07575602 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0158376 0,07560571 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0158376 0,07545599 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0158376 0,07530687 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0158376 0,07515834 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0158376 0,07501039 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0158376 0,07486302 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0158376 0,07471623 ! striatum development GO:0021756 9 5 0,000 0,0158376 0,07457001 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0158376 0,07442437 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0158376 0,07427929 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0158376 0,07413478 ! glial cell migration GO:0008347 11 5 0,000 0,0158376 0,07399083 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0158376 0,07384744 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0158376 0,0737046 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0158376 0,07356231 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0158376 0,07342057 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0158376 0,07327938 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0158376 0,07313873 ! neuroprotection GO:0043526 6 5 0,000 0,0158376 0,07299862 ! neural plate development GO:0001840 8 5 0,000 0,0158376 0,07285904 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0158376 0,07272 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0158376 0,07258148 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0158376 0,07244349 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0158376 0,07230603 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0158376 0,07216909 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0158376 0,07203266 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0158376 0,07189675 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0158376 0,07176135 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0158376 0,07162646 ! spindle assembly GO:0051225 6 5 0,000 0,0158376 0,07149208 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0158376 0,0713582 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0158376 0,07122482 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0158376 0,07109194 ! drug metabolic process GO:0017144 6 5 0,000 0,0158376 0,07095955 ! stem cell division GO:0017145 11 5 0,000 0,0158376 0,07082765 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0158376 0,07069625 ! organ regeneration GO:0031100 7 5 0,000 0,0158376 0,07056533 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0158376 0,07043489 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0158376 0,07030494 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0158376 0,07017546 ! viral reproductive process GO:0022415 126 62 1,000 0,01679497 0,07428071 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01679497 0,07414442 ! regulation of mitosis GO:0007088 105 63 1,000 0,01731005 0,07627837 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01731005 0,07613892 ! single fertilization GO:0007338 75 64 1,000 0,0178318 0,07829073 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01897521 0,08315912 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01897521 0,08300792 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01897521 0,08285727 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01897521 0,08270717 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01897521 0,08255761 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01897521 0,08240859 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01897521 0,0822601 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01897521 0,08211215 ! sleep GO:0030431 13 6 0,000 0,01897521 0,08196473 ! response to oxygen radical GO:0000305 11 6 0,000 0,01897521 0,08181784 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01897521 0,08167148 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01897521 0,08152564 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01897521 0,08138032 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01897521 0,08123551 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01897521 0,08109122 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01897521 0,08094744 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01897521 0,08080417 ! forebrain regionalization GO:0021871 8 6 0,000 0,01897521 0,08066141 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01897521 0,08051915 ! male meiosis GO:0007140 7 6 0,000 0,01897521 0,08037739 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01897521 0,08023613 ! response to zinc ion GO:0010043 9 6 0,000 0,01897521 0,08009536 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01897521 0,07995509 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01897521 0,07981531 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01897521 0,07967602 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01897521 0,07953721 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01897521 0,07939888 ! malate metabolic process GO:0006108 11 6 0,000 0,01897521 0,07926104 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01897521 0,07912367 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01897521 0,07898678 ! protein refolding GO:0042026 15 6 0,000 0,01897521 0,07885036 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01897521 0,07871441 ! opsonization GO:0008228 8 6 0,000 0,01897521 0,07857893 ! mating behavior GO:0007617 7 6 0,000 0,01897521 0,07844391 ! neuron remodeling GO:0016322 15 6 0,000 0,01897521 0,07830936 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01897521 0,07817527 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01897521 0,07804164 ! equilibrioception GO:0050957 14 6 0,000 0,01897521 0,07790846 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01897521 0,07777574 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01897521 0,07764346 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01897521 0,07751164 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01897521 0,07738027 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01897521 0,07724934 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01897521 0,07711885 ! toxin metabolic process GO:0009404 11 6 0,000 0,01897521 0,0769888 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01897521 0,07685919 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01897521 0,07673001 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01897521 0,07660127 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01897521 0,07647296 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01897521 0,07634508 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01897521 0,07621762 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01897521 0,0760906 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01897521 0,07596399 ! thymic T cell selection GO:0045061 12 6 0,000 0,01897521 0,0758378 ! protein lipoylation GO:0009249 10 6 0,000 0,01897521 0,07571204 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01897521 0,07558668 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01897521 0,07546175 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01897521 0,07533722 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01897521 0,07521311 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01897521 0,0750894 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01897521 0,0749661 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01897521 0,07484321 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01897521 0,07472072 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01897521 0,07459862 ! hyperosmotic response GO:0006972 9 6 0,000 0,01897521 0,07447693 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01897521 0,07435563 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01897521 0,07423473 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01897521 0,07411422 ! urea metabolic process GO:0019627 7 6 0,000 0,01897521 0,0739941 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01897521 0,07387436 ! neutrophil activation GO:0042119 8 6 0,000 0,01897521 0,07375502 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01897521 0,07363606 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01897521 0,07351748 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01897521 0,07339929 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01897521 0,07328147 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01897521 0,07316403 ! neuron apoptosis GO:0051402 9 6 0,000 0,01897521 0,07304697 ! nucleoside salvage GO:0043174 9 6 0,000 0,01897521 0,07293028 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01897521 0,07281397 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01897521 0,07269802 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01897521 0,07258244 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01897521 0,07246723 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01897521 0,07235239 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01897521 0,07223791 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01897521 0,07212379 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01897521 0,07201003 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01897521 0,07189663 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01897521 0,07178358 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01897521 0,07167089 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01897521 0,07155855 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01897521 0,07144657 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01897521 0,07133493 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01897521 0,07122365 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01897521 0,07111271 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01897521 0,07100211 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01897521 0,07089186 ! neural nucleus development GO:0048857 14 6 0,000 0,01897521 0,07078195 ! response to UV-C GO:0010225 11 6 0,000 0,01897521 0,07067238 ! astrocyte development GO:0014002 15 6 0,000 0,01897521 0,07056315 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01897521 0,07045426 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01897521 0,0703457 ! interaction with symbiont GO:0051702 13 6 0,000 0,01897521 0,07023747 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01897521 0,07012958 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01897521 0,07002202 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01897521 0,06991479 ! response to copper ion GO:0046688 10 6 0,000 0,01897521 0,06980789 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01897521 0,06970131 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01897521 0,06959506 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01897521 0,06948913 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01897521 0,06938352 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01897521 0,06927824 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01897521 0,06917327 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01897521 0,06906862 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01897521 0,06896429 ! hair follicle maturation GO:0048820 7 6 0,000 0,01897521 0,06886027 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01897521 0,06875656 ! Schwann cell development GO:0014044 15 6 0,000 0,01897521 0,06865317 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01897521 0,06855009 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01897521 0,06844731 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01897521 0,06834485 ! subpallium development GO:0021544 10 6 0,000 0,01897521 0,06824269 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01897521 0,06814083 ! histone ubiquitination GO:0016574 8 6 0,000 0,01897521 0,06803928 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01897521 0,06793803 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01897521 0,06783708 ! G2 phase GO:0051319 16 6 0,000 0,01897521 0,06773644 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01897521 0,06763608 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01897521 0,06753603 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01897521 0,06743627 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01897521 0,06733681 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01897521 0,06723764 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01897521 0,06713876 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01897521 0,06704017 ! receptor internalization GO:0031623 10 6 0,000 0,01897521 0,06694187 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01897521 0,06684386 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01897521 0,06674614 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01897521 0,0666487 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01897521 0,06655154 ! protein deubiquitination GO:0016579 14 6 0,000 0,01897521 0,06645467 ! protein destabilization GO:0031648 9 6 0,000 0,01897521 0,06635808 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01897521 0,06626177 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01897521 0,06616574 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01897521 0,06606998 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01897521 0,0659745 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01897521 0,0658793 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01897521 0,06578438 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01897521 0,06568972 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01897521 0,06559534 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01897521 0,06550123 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01897521 0,06540739 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01897521 0,06531382 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01897521 0,06522051 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01897521 0,06512747 ! catecholamine transport GO:0051937 9 6 0,000 0,01897521 0,0650347 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01897521 0,06494219 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01897521 0,06484994 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01897521 0,06475795 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01897521 0,06466623 ! maternal placenta development GO:0001893 12 6 0,000 0,01897521 0,06457476 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01897521 0,06448356 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01897521 0,06439261 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01897521 0,06430191 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01897521 0,06421147 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01897521 0,06412129 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01897521 0,06403136 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01897521 0,06394168 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,01943661 0,06540488 ! lung development GO:0030324 144 67 1,000 0,01943661 0,06531353 ! chromosome segregation GO:0007059 113 67 1,000 0,01943661 0,06522244 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,01998458 0,06696782 ! viral reproduction GO:0016032 134 68 1,000 0,01998458 0,06687468 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01998458 0,0667818 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,01998458 0,06668918 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02053899 0,06844432 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,02053899 0,06834965 ! respiratory tube development GO:0030323 150 70 1,000 0,02109978 0,0701189 ! B cell activation GO:0042113 160 71 1,000 0,02166693 0,07190433 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,02166693 0,07180529 ! tRNA transcription GO:0009304 14 7 0,000 0,02210292 0,07314941 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02210292 0,07304893 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02210292 0,07294872 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02210292 0,07284879 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02210292 0,07274914 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02210292 0,07264975 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02210292 0,07255064 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02210292 0,0724518 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02210292 0,07235322 ! prostate gland development GO:0030850 13 7 0,000 0,02210292 0,07225492 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02210292 0,07215688 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02210292 0,07205911 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02210292 0,0719616 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02210292 0,07186435 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02210292 0,07176737 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02210292 0,07167065 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02210292 0,07157419 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02210292 0,07147798 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02210292 0,07138204 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02210292 0,07128635 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02210292 0,07119092 ! glycolipid transport GO:0046836 10 7 0,000 0,02210292 0,07109575 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02210292 0,07100083 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02210292 0,07090616 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02210292 0,07081174 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02210292 0,07071758 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02210292 0,07062367 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02210292 0,07053 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02210292 0,07043658 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02210292 0,07034341 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02210292 0,07025049 ! mRNA stabilization GO:0048255 18 7 0,000 0,02210292 0,07015781 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02210292 0,07006538 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02210292 0,06997318 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02210292 0,06988124 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02210292 0,06978953 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02210292 0,06969806 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02210292 0,06960683 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02210292 0,06951584 ! lipoprotein transport GO:0042953 14 7 0,000 0,02210292 0,06942509 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02210292 0,06933458 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02210292 0,0692443 ! rhythmic behavior GO:0007622 15 7 0,000 0,02210292 0,06915425 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02210292 0,06906444 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02210292 0,06897486 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02210292 0,06888552 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02210292 0,0687964 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02210292 0,06870752 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02210292 0,06861886 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02210292 0,06853044 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02210292 0,06844224 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02210292 0,06835427 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02210292 0,06826652 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02210292 0,068179 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02210292 0,0680917 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02210292 0,06800463 ! spinal cord patterning GO:0021511 13 7 0,000 0,02210292 0,06791778 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02210292 0,06783115 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02210292 0,06774474 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02210292 0,06765855 ! adrenal gland development GO:0030325 17 7 0,000 0,02210292 0,06757258 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02210292 0,06748683 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02210292 0,06740129 ! ovulation GO:0030728 9 7 0,000 0,02210292 0,06731597 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02210292 0,06723087 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02210292 0,06714598 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02210292 0,06706131 ! microtubule nucleation GO:0007020 20 7 0,000 0,02210292 0,06697685 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02210292 0,0668926 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02210292 0,06680857 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02210292 0,06672474 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02210292 0,06664113 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02210292 0,06655772 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02210292 0,06647452 ! galactose metabolic process GO:0006012 13 7 0,000 0,02210292 0,06639154 ! vesicle fusion GO:0006906 17 7 0,000 0,02210292 0,06630875 ! response to dietary excess GO:0002021 8 7 0,000 0,02210292 0,06622618 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02210292 0,06614381 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02210292 0,06606164 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02210292 0,06597968 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02210292 0,06589792 ! organ growth GO:0035265 15 7 0,000 0,02210292 0,06581636 ! purine salvage GO:0043101 10 7 0,000 0,02210292 0,06573501 ! nucleoside transport GO:0015858 8 7 0,000 0,02210292 0,06565385 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02210292 0,0655729 ! parturition GO:0007567 14 7 0,000 0,02210292 0,06549214 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02210292 0,06541159 ! rRNA modification GO:0000154 14 7 0,000 0,02210292 0,06533123 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02210292 0,06525107 ! spindle checkpoint GO:0031577 15 7 0,000 0,02210292 0,0651711 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02210292 0,06509133 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02210292 0,06501176 ! macrophage differentiation GO:0030225 11 7 0,000 0,02210292 0,06493238 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02210292 0,06485319 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02210292 0,0647742 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02210292 0,0646954 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02210292 0,06461679 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02210292 0,06453837 ! eating behavior GO:0042755 7 7 0,000 0,02210292 0,06446015 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02210292 0,06438211 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02210292 0,06430426 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02210292 0,06422659 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02210292 0,06414912 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02210292 0,06407183 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02210292 0,06399473 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02210292 0,06391781 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02210292 0,06384108 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02210292 0,06376453 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02210292 0,06368817 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02210292 0,06361199 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02210292 0,06353599 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02210292 0,06346017 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02210292 0,06338453 ! regulation of meiosis GO:0040020 12 7 0,000 0,02210292 0,06330907 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02210292 0,06323379 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02210292 0,06315869 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02210292 0,06308377 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02210292 0,06300903 ! transcription termination GO:0006353 13 7 0,000 0,02210292 0,06293446 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02210292 0,06286007 ! anaphase GO:0051322 17 7 0,000 0,02210292 0,06278586 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02210292 0,06271182 ! axonal fasciculation GO:0007413 18 7 0,000 0,02210292 0,06263795 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02210292 0,06256426 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02210292 0,06249074 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02210292 0,06241739 ! diuresis GO:0030146 12 7 0,000 0,02210292 0,06234422 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02210292 0,06227122 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02210292 0,06219839 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02210292 0,06212572 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02210292 0,06205323 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02210292 0,06198091 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02210292 0,06190875 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02210292 0,06183677 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02210292 0,06176495 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02210292 0,06169329 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02210292 0,06162181 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02210292 0,06155049 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02210292 0,06147933 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02210292 0,06140834 ! lymph node development GO:0048535 10 7 0,000 0,02210292 0,06133751 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02210292 0,06126684 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02210292 0,06119634 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02210292 0,061126 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02210292 0,06105582 ! adult feeding behavior GO:0008343 9 7 0,000 0,02210292 0,0609858 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02210292 0,06091594 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02210292 0,06084625 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02210292 0,06077671 ! muscle adaptation GO:0043500 14 7 0,000 0,02210292 0,06070733 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02210292 0,06063811 ! retina homeostasis GO:0001895 12 7 0,000 0,02210292 0,06056904 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02210292 0,06050014 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02210292 0,06043139 ! protein prenylation GO:0018342 18 7 0,000 0,02210292 0,06036279 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02210292 0,06029435 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02210292 0,06022607 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02210292 0,06015794 ! regulation of caspase activity GO:0043281 122 72 1,000 0,02224038 0,06046368 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02224038 0,06039544 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,02224038 0,06032735 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,02224038 0,06025941 ! respiratory system development GO:0060541 153 72 1,000 0,02224038 0,06019163 ! axon guidance GO:0007411 139 73 1,000 0,02282009 0,06169116 ! fertilization GO:0009566 90 73 1,000 0,02282009 0,06162192 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02340601 0,06313324 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,02399809 0,0646578 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02399809 0,06458547 ! regulation of catabolic process GO:0009894 161 76 1,000 0,0245963 0,06612146 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,02520059 0,06767035 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02520059 0,06759491 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02522076 0,06757365 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02522076 0,06749849 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02522076 0,06742349 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02522076 0,06734866 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02522076 0,06727399 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02522076 0,06719949 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02522076 0,06712515 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02522076 0,06705098 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02522076 0,06697698 ! meiotic prophase I GO:0007128 13 8 0,000 0,02522076 0,06690313 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02522076 0,06682945 ! oligopeptide transport GO:0006857 15 8 0,000 0,02522076 0,06675593 ! UTP metabolic process GO:0046051 8 8 0,000 0,02522076 0,06668257 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02522076 0,06660937 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02522076 0,06653634 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02522076 0,06646346 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02522076 0,06639074 ! succinate metabolic process GO:0006105 14 8 0,000 0,02522076 0,06631819 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02522076 0,06624579 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02522076 0,06617354 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02522076 0,06610146 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02522076 0,06602953 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02522076 0,06595776 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02522076 0,06588614 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02522076 0,06581468 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02522076 0,06574338 ! reflex GO:0060004 16 8 0,000 0,02522076 0,06567223 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02522076 0,06560123 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02522076 0,06553039 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02522076 0,0654597 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02522076 0,06538916 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02522076 0,06531877 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02522076 0,06524854 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02522076 0,06517845 ! pigment granule organization GO:0048753 16 8 0,000 0,02522076 0,06510852 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02522076 0,06503873 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02522076 0,0649691 ! histidine metabolic process GO:0006547 16 8 0,000 0,02522076 0,06489961 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02522076 0,06483028 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02522076 0,06476109 ! glycine catabolic process GO:0006546 13 8 0,000 0,02522076 0,06469205 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02522076 0,06462315 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02522076 0,0645544 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02522076 0,0644858 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02522076 0,06441735 ! melanin metabolic process GO:0006582 15 8 0,000 0,02522076 0,06434903 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02522076 0,06428087 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02522076 0,06421285 ! macrophage activation GO:0042116 12 8 0,000 0,02522076 0,06414497 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02522076 0,06407723 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02522076 0,06400964 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02522076 0,06394219 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02522076 0,06387488 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02522076 0,06380772 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02522076 0,06374069 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02522076 0,06367381 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02522076 0,06360706 ! osteoblast development GO:0002076 16 8 0,000 0,02522076 0,06354046 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02522076 0,063474 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02522076 0,06340767 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02522076 0,06334148 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02522076 0,06327543 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02522076 0,06320952 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02522076 0,06314375 ! response to UV-B GO:0010224 16 8 0,000 0,02522076 0,06307811 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02522076 0,06301261 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02522076 0,06294724 ! intermediate filament organization GO:0045109 12 8 0,000 0,02522076 0,06288201 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02522076 0,06281691 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02522076 0,06275195 ! cellular extravasation GO:0045123 12 8 0,000 0,02522076 0,06268713 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02522076 0,06262244 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02522076 0,06255788 ! response to antibiotic GO:0046677 11 8 0,000 0,02522076 0,06249345 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02522076 0,06242916 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02522076 0,06236499 ! DNA topological change GO:0006265 12 8 0,000 0,02522076 0,06230096 ! response to tropane GO:0014073 15 8 0,000 0,02522076 0,06223707 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02522076 0,0621733 ! melanosome transport GO:0032402 13 8 0,000 0,02522076 0,06210966 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02522076 0,06204615 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02522076 0,06198278 ! mast cell activation GO:0045576 14 8 0,000 0,02522076 0,06191953 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02522076 0,06185641 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02522076 0,06179342 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02522076 0,06173056 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02522076 0,06166782 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02522076 0,06160522 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02522076 0,06154274 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02522076 0,06148038 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02522076 0,06141816 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02522076 0,06135606 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02522076 0,06129408 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02522076 0,06123223 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02522076 0,0611705 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02522076 0,0611089 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02522076 0,06104742 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02522076 0,06098607 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02522076 0,06092484 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02522076 0,06086373 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02522076 0,06080275 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02522076 0,06074188 ! hormone catabolic process GO:0042447 17 8 0,000 0,02522076 0,06068114 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02522076 0,06062052 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02522076 0,06056002 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02522076 0,06049964 ! ATP catabolic process GO:0006200 11 8 0,000 0,02522076 0,06043938 ! blastocyst growth GO:0001832 19 8 0,000 0,02522076 0,06037924 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02522076 0,06031922 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02522076 0,06025932 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02522076 0,06019954 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02522076 0,06013988 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02522076 0,06008034 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02522076 0,06002091 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02522076 0,0599616 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02522076 0,05990241 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02522076 0,05984333 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02522076 0,05978437 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02522076 0,05972553 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02522076 0,0596668 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02522076 0,05960819 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02522076 0,0595497 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02522076 0,05949131 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02522076 0,05943305 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,02581092 0,06076426 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02581092 0,06070486 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02642724 0,06209368 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,02642724 0,06203311 ! protein import into nucleus GO:0006606 158 80 1,000 0,0270495 0,06343187 ! T cell activation GO:0042110 168 81 1,000 0,02767767 0,06484175 ! response to hypoxia GO:0001666 171 81 1,000 0,02767767 0,06477868 ! nuclear import GO:0051170 161 81 1,000 0,02767767 0,06471572 ! response to drug GO:0042493 143 82 1,000 0,0283117 0,06613394 ! axon extension GO:0048675 15 9 0,000 0,02832876 0,06610959 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02832876 0,06604553 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02832876 0,0659816 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02832876 0,06591779 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02832876 0,0658541 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02832876 0,06579053 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02832876 0,06572709 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02832876 0,06566377 ! phosphate transport GO:0006817 19 9 0,000 0,02832876 0,06560057 ! reproductive behavior GO:0019098 19 9 0,000 0,02832876 0,06553749 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02832876 0,06547453 ! CTP metabolic process GO:0046036 9 9 0,000 0,02832876 0,0654117 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02832876 0,06534898 ! GTP metabolic process GO:0046039 9 9 0,000 0,02832876 0,06528639 ! RNA methylation GO:0001510 15 9 0,000 0,02832876 0,06522391 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02832876 0,06516156 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02832876 0,06509932 ! artery development GO:0060840 24 9 0,000 0,02832876 0,0650372 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02832876 0,06497521 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02832876 0,06491332 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02832876 0,06485156 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02832876 0,06478991 ! chemosensory behavior GO:0007635 20 9 0,000 0,02832876 0,06472839 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02832876 0,06466697 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02832876 0,06460568 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02832876 0,0645445 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02832876 0,06448343 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02832876 0,06442249 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02832876 0,06436165 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02832876 0,06430093 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02832876 0,06424033 ! protein targeting to ER GO:0045047 22 9 0,000 0,02832876 0,06417984 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02832876 0,06411946 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02832876 0,0640592 ! T cell selection GO:0045058 23 9 0,000 0,02832876 0,06399905 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02832876 0,06393902 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02832876 0,06387909 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02832876 0,06381928 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02832876 0,06375958 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02832876 0,06369999 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02832876 0,06364051 ! mannose metabolic process GO:0006013 13 9 0,000 0,02832876 0,06358115 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02832876 0,06352189 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02832876 0,06346275 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02832876 0,06340371 ! receptor clustering GO:0043113 18 9 0,000 0,02832876 0,06334479 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02832876 0,06328597 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02832876 0,06322726 ! ruffle organization GO:0031529 15 9 0,000 0,02832876 0,06316867 ! retinol metabolic process GO:0042572 18 9 0,000 0,02832876 0,06311018 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02832876 0,06305179 ! behavioral fear response GO:0001662 22 9 0,000 0,02832876 0,06299352 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02832876 0,06293536 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02832876 0,0628773 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02832876 0,06281935 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02832876 0,0627615 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02832876 0,06270376 ! segment specification GO:0007379 13 9 0,000 0,02832876 0,06264613 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02832876 0,0625886 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02832876 0,06253118 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02832876 0,06247387 ! response to amine stimulus GO:0014075 13 9 0,000 0,02832876 0,06241666 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02832876 0,06235955 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02832876 0,06230255 ! erythrocyte development GO:0048821 15 9 0,000 0,02832876 0,06224565 ! gas homeostasis GO:0033483 16 9 0,000 0,02832876 0,06218886 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02832876 0,06213217 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02832876 0,06207558 ! renal water homeostasis GO:0003091 14 9 0,000 0,02832876 0,0620191 ! postreplication repair GO:0006301 22 9 0,000 0,02832876 0,06196272 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02832876 0,06190644 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02832876 0,06185026 ! icosanoid secretion GO:0032309 15 9 0,000 0,02832876 0,06179419 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02832876 0,06173822 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02832876 0,06168234 ! regulation of cell division GO:0051302 15 9 0,000 0,02832876 0,06162657 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02832876 0,0615709 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02832876 0,06151533 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02832876 0,06145987 ! sterol catabolic process GO:0016127 11 9 0,000 0,02832876 0,0614045 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02832876 0,06134923 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02832876 0,06129406 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02832876 0,06123899 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02832876 0,06118401 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02832876 0,06112914 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02832876 0,06107436 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02832876 0,06101969 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02832876 0,06096511 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02832876 0,06091063 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02832876 0,06085624 ! purine base metabolic process GO:0006144 21 9 0,000 0,02832876 0,06080195 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02832876 0,06074776 ! pigment granule transport GO:0051904 17 9 0,000 0,02832876 0,06069367 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02832876 0,06063967 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02832876 0,06058577 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02832876 0,06053196 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02832876 0,06047825 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02832876 0,06042464 ! mitochondrion localization GO:0051646 15 9 0,000 0,02832876 0,06037112 ! response to oxygen levels GO:0070482 176 83 1,000 0,02895155 0,06164375 ! regulation of ligase activity GO:0051340 142 84 1,000 0,02959718 0,0629627 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,03024854 0,06429151 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,03090559 0,06563006 ! mitochondrion organization GO:0007005 148 86 1,000 0,03090559 0,06557218 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03142695 0,0666196 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03142695 0,06656096 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03142695 0,06650242 ! synapsis GO:0007129 13 10 0,000 0,03142695 0,06644398 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03142695 0,06638564 ! N-glycan processing GO:0006491 20 10 0,000 0,03142695 0,06632741 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03142695 0,06626928 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03142695 0,06621125 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03142695 0,06615332 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03142695 0,06609549 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03142695 0,06603777 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03142695 0,06598015 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03142695 0,06592262 ! androgen metabolic process GO:0008209 17 10 0,000 0,03142695 0,0658652 ! phospholipid efflux GO:0033700 16 10 0,000 0,03142695 0,06580787 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03142695 0,06575065 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03142695 0,06569352 ! lung alveolus development GO:0048286 26 10 0,000 0,03142695 0,0656365 ! pathogenesis GO:0009405 13 10 0,000 0,03142695 0,06557957 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03142695 0,06552274 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03142695 0,06546601 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03142695 0,06540938 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03142695 0,06535285 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03142695 0,06529641 ! endoderm development GO:0007492 16 10 0,000 0,03142695 0,06524007 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03142695 0,06518383 ! arginine catabolic process GO:0006527 13 10 0,000 0,03142695 0,06512769 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03142695 0,06507164 ! proline metabolic process GO:0006560 13 10 0,000 0,03142695 0,06501569 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03142695 0,06495983 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03142695 0,06490407 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03142695 0,06484841 ! V(D)J recombination GO:0033151 28 10 0,000 0,03142695 0,06479284 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03142695 0,06473737 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03142695 0,06468199 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03142695 0,06462671 ! B cell proliferation GO:0042100 18 10 0,000 0,03142695 0,06457152 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03142695 0,06451642 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03142695 0,06446142 ! multicellular organism growth GO:0035264 18 10 0,000 0,03142695 0,06440651 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03142695 0,0643517 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03142695 0,06429698 ! epithelial cell development GO:0002064 20 10 0,000 0,03142695 0,06424235 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03142695 0,06418782 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03142695 0,06413337 ! macroautophagy GO:0016236 17 10 0,000 0,03142695 0,06407902 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03142695 0,06402476 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03142695 0,0639706 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03142695 0,06391652 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03142695 0,06386254 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03142695 0,06380865 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03142695 0,06375485 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03142695 0,06370113 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03142695 0,06364751 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03142695 0,06359398 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03142695 0,06354054 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03142695 0,06348719 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03142695 0,06343393 ! response to dsRNA GO:0043331 20 10 0,000 0,03142695 0,06338076 ! DNA ligation GO:0006266 19 10 0,000 0,03142695 0,06332768 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03142695 0,06327468 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03142695 0,06322178 ! melanosome localization GO:0032400 16 10 0,000 0,03142695 0,06316896 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03142695 0,06311623 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03142695 0,06306359 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03142695 0,06301104 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03142695 0,06295857 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03142695 0,06290619 ! mRNA cleavage GO:0006379 17 10 0,000 0,03142695 0,0628539 ! protein sumoylation GO:0016925 15 10 0,000 0,03142695 0,0628017 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03142695 0,06274958 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03142695 0,06269755 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03142695 0,06264561 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03142695 0,06259375 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03142695 0,06254197 ! salivary gland development GO:0007431 27 10 0,000 0,03142695 0,06249029 ! prophase GO:0051324 15 10 0,000 0,03142695 0,06243868 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03142695 0,06238717 ! apical protein localization GO:0045176 15 10 0,000 0,03142695 0,06233573 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03142695 0,06228439 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03142695 0,06223312 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03142695 0,06218195 ! midbrain development GO:0030901 13 10 0,000 0,03142695 0,06213085 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03142695 0,06207984 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03142695 0,06202891 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03142695 0,06197807 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03142695 0,06192731 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03142695 0,06187663 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03142695 0,06182604 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03142695 0,06177553 ! detection of calcium ion GO:0005513 23 10 0,000 0,03142695 0,0617251 ! oocyte development GO:0048599 17 10 0,000 0,03142695 0,06167475 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03142695 0,06162449 ! blastocyst formation GO:0001825 17 10 0,000 0,03142695 0,0615743 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03142695 0,0615242 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03142695 0,06147418 ! activation of innate immune response GO:0002218 12 10 0,000 0,03142695 0,06142425 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03142695 0,06137439 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03142695 0,06132461 ! response to nicotine GO:0035094 20 10 0,000 0,03142695 0,06127492 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03142695 0,0612253 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03142695 0,06117577 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03142695 0,06112631 ! protein localization in nucleus GO:0034504 176 87 1,000 0,03156829 0,06135162 ! gland development GO:0048732 206 88 1,000 0,0322366 0,06259989 ! ossification GO:0001503 188 90 1,000 0,03358987 0,06517518 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03358987 0,06512267 ! bone development GO:0060348 189 91 1,000 0,03427475 0,06639698 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03451537 0,06680932 ! respiratory burst GO:0045730 17 11 0,000 0,03451537 0,06675561 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03451537 0,06670199 ! neuron fate specification GO:0048665 17 11 0,000 0,03451537 0,06664846 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03451537 0,06659501 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03451537 0,06654165 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03451537 0,06648838 ! thyroid gland development GO:0030878 26 11 0,000 0,03451537 0,06643518 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03451537 0,06638208 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03451537 0,06632906 ! response to pain GO:0048265 24 11 0,000 0,03451537 0,06627612 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03451537 0,06622327 ! T cell proliferation GO:0042098 26 11 0,000 0,03451537 0,0661705 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03451537 0,06611782 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03451537 0,06606522 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03451537 0,0660127 ! bone resorption GO:0045453 16 11 0,000 0,03451537 0,06596027 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,03451537 0,06590792 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03451537 0,06585565 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03451537 0,06580347 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03451537 0,06575137 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03451537 0,06569935 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03451537 0,06564742 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03451537 0,06559556 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03451537 0,06554379 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03451537 0,0654921 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03451537 0,06544049 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03451537 0,06538896 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03451537 0,06533751 ! UV protection GO:0009650 19 11 0,000 0,03451537 0,06528615 ! adult heart development GO:0007512 14 11 0,000 0,03451537 0,06523486 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03451537 0,06518366 ! temperature homeostasis GO:0001659 17 11 0,000 0,03451537 0,06513253 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03451537 0,06508149 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03451537 0,06503053 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03451537 0,06497964 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03451537 0,06492884 ! regulation of organ growth GO:0046620 13 11 0,000 0,03451537 0,06487811 ! pigment granule localization GO:0051875 20 11 0,000 0,03451537 0,06482746 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03451537 0,0647769 ! vasoconstriction GO:0042310 18 11 0,000 0,03451537 0,06472641 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03451537 0,064676 ! embryonic axis specification GO:0000578 18 11 0,000 0,03451537 0,06462567 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03451537 0,06457541 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03451537 0,06452524 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03451537 0,06447514 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03451537 0,06442512 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03451537 0,06437518 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03451537 0,06432531 ! zymogen activation GO:0031638 15 11 0,000 0,03451537 0,06427553 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03451537 0,06422582 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03451537 0,06417618 ! nucleosome positioning GO:0016584 15 11 0,000 0,03451537 0,06412663 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03451537 0,06407715 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03451537 0,06402774 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03451537 0,06397841 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03451537 0,06392916 ! acid secretion GO:0046717 18 11 0,000 0,03451537 0,06387999 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03451537 0,06383088 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03451537 0,06378186 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03451537 0,06373291 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03451537 0,06368403 ! oocyte differentiation GO:0009994 18 11 0,000 0,03451537 0,06363523 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03451537 0,06358651 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03451537 0,06353786 ! cholesterol efflux GO:0033344 19 11 0,000 0,03451537 0,06348928 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03451537 0,06344078 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03451537 0,06339235 ! germ cell migration GO:0008354 25 11 0,000 0,03451537 0,063344 ! embryonic gut development GO:0048566 15 11 0,000 0,03451537 0,06329572 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03451537 0,06324751 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03451537 0,06319938 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03451537 0,06315132 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03451537 0,06310333 ! defense response to fungus GO:0050832 13 11 0,000 0,03451537 0,06305541 ! lysogeny GO:0030069 21 11 0,000 0,03451537 0,06300757 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03451537 0,0629598 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03451537 0,06291211 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03451537 0,06286448 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03451537 0,06281693 ! nucleus localization GO:0051647 19 11 0,000 0,03451537 0,06276945 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03451537 0,06272204 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,0356608 0,06475462 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,0356608 0,06470579 ! transcription initiation GO:0006352 153 94 1,000 0,03636188 0,06592817 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03636188 0,06587853 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,03706828 0,06710782 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03759404 0,06800847 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03759404 0,06795738 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03759404 0,06790636 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03759404 0,06785541 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03759404 0,06780455 ! cartilage condensation GO:0001502 20 12 0,000 0,03759404 0,06775376 ! mating GO:0007618 17 12 0,000 0,03759404 0,06770304 ! protein complex disassembly GO:0043241 27 12 0,000 0,03759404 0,06765241 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03759404 0,06760184 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03759404 0,06755136 ! hippocampus development GO:0021766 26 12 0,000 0,03759404 0,06750095 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03759404 0,06745061 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03759404 0,06740035 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03759404 0,06735016 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03759404 0,06730005 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03759404 0,06725001 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03759404 0,06720005 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03759404 0,06715016 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03759404 0,06710035 ! drug transport GO:0015893 16 12 0,000 0,03759404 0,06705061 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03759404 0,06700094 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03759404 0,06695135 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03759404 0,06690183 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03759404 0,06685238 ! focal adhesion formation GO:0048041 35 12 0,000 0,03759404 0,066803 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03759404 0,0667537 ! forebrain cell migration GO:0021885 21 12 0,000 0,03759404 0,06670447 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03759404 0,06665532 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03759404 0,06660624 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03759404 0,06655722 ! entry into host cell GO:0030260 32 12 0,000 0,03759404 0,06650829 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03759404 0,06645942 ! monoamine transport GO:0015844 18 12 0,000 0,03759404 0,06641062 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03759404 0,0663619 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03759404 0,06631325 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03759404 0,06626467 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03759404 0,06621616 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03759404 0,06616772 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03759404 0,06611935 ! protein homotetramerization GO:0051289 21 12 0,000 0,03759404 0,06607105 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03759404 0,06602282 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03759404 0,06597467 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03759404 0,06592658 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03759404 0,06587856 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03759404 0,06583062 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03759404 0,06578274 ! cranial nerve development GO:0021545 20 12 0,000 0,03759404 0,06573493 ! fucose catabolic process GO:0019317 22 12 0,000 0,03759404 0,0656872 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03759404 0,06563953 ! histone acetylation GO:0016573 26 12 0,000 0,03759404 0,06559193 ! histone methylation GO:0016571 26 12 0,000 0,03759404 0,0655444 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03759404 0,06549694 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03759404 0,06544954 ! gland morphogenesis GO:0022612 29 12 0,000 0,03759404 0,06540222 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03759404 0,06535496 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03759404 0,06530777 ! T cell homeostasis GO:0043029 25 12 0,000 0,03759404 0,06526065 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03759404 0,0652136 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03759404 0,06516662 ! spleen development GO:0048536 22 12 0,000 0,03759404 0,0651197 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03759404 0,06507285 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03759404 0,06502607 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03759404 0,06497936 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03759404 0,06493271 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03759404 0,06488613 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03759404 0,06483962 ! response to cold GO:0009409 17 12 0,000 0,03759404 0,06479317 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03759404 0,06474679 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03759404 0,06470048 ! leukocyte differentiation GO:0002521 202 96 1,000 0,03777997 0,06497398 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03994629 0,06865056 GO:0060538|skeletal muscle organ development, ! cGMP metabolic process GO:0046068 18 13 0,000 0,040663 0,06983239 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,040663 0,06978258 ! regulation of chemokine production GO:0032642 18 13 0,000 0,040663 0,06973284 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,040663 0,06968318 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,040663 0,06963358 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,040663 0,06958405 ! lipid localization GO:0010876 28 13 0,000 0,040663 0,0695346 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,040663 0,06948521 ! organelle fusion GO:0048284 32 13 0,000 0,040663 0,0694359 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,040663 0,06938665 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,040663 0,06933748 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,040663 0,06928837 ! endocrine pancreas development GO:0031018 22 13 0,000 0,040663 0,06923933 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,040663 0,06919037 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,040663 0,06914147 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,040663 0,06909264 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,040663 0,06904388 ! methionine metabolic process GO:0006555 27 13 0,000 0,040663 0,06899519 ! plasma membrane organization GO:0007009 24 13 0,000 0,040663 0,06894657 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,040663 0,06889801 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,040663 0,06884953 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,040663 0,06880111 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,040663 0,06875276 ! cytokine metabolic process GO:0042107 22 13 0,000 0,040663 0,06870448 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,040663 0,06865627 ! exocrine system development GO:0035272 32 13 0,000 0,040663 0,06860812 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,040663 0,06856004 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,040663 0,06851203 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,040663 0,06846409 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,040663 0,06841621 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,040663 0,0683684 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,040663 0,06832066 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,040663 0,06827298 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,040663 0,06822537 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,040663 0,06817783 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,040663 0,06813035 ! ribosome assembly GO:0042255 17 13 0,000 0,040663 0,06808294 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,040663 0,06803559 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,040663 0,06798831 ! chromatin silencing GO:0006342 26 13 0,000 0,040663 0,0679411 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,040663 0,06789395 ! regulation of epidermis development GO:0045682 19 13 0,000 0,040663 0,06784687 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,040663 0,06779985 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,040663 0,06775289 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,040663 0,06770601 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,040663 0,06765918 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,040663 0,06761243 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,040663 0,06756573 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,040663 0,0675191 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,040663 0,06747254 ! embryonic placenta development GO:0001892 23 13 0,000 0,040663 0,06742604 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,040663 0,0673796 ! insulin secretion GO:0030073 23 13 0,000 0,040663 0,06733323 ! actin filament polymerization GO:0030041 24 13 0,000 0,040663 0,06728692 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,040663 0,06724067 ! acrosome reaction GO:0007340 18 13 0,000 0,040663 0,06719449 ! rRNA transcription GO:0009303 25 14 0,000 0,04372227 0,07220027 ! lactation GO:0007595 26 14 0,000 0,04372227 0,07215075 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,04372227 0,0721013 ! reproductive cellular process GO:0048610 20 14 0,000 0,04372227 0,07205191 ! tRNA modification GO:0006400 20 14 0,000 0,04372227 0,07200259 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04372227 0,07195335 ! regulation of S phase GO:0033261 23 14 0,000 0,04372227 0,07190416 ! water transport GO:0006833 21 14 0,000 0,04372227 0,07185505 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04372227 0,071806 ! non-recombinational repair GO:0000726 25 14 0,000 0,04372227 0,07175702 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04372227 0,07170811 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04372227 0,07165926 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04372227 0,07161048 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04372227 0,07156176 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04372227 0,07151311 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04372227 0,07146453 ! palate development GO:0060021 31 14 0,000 0,04372227 0,07141602 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04372227 0,07136756 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04372227 0,07131918 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04372227 0,07127086 ! arginine metabolic process GO:0006525 17 14 0,000 0,04372227 0,07122261 ! regulation of heart rate GO:0002027 24 14 0,000 0,04372227 0,07117442 ! organic alcohol transport GO:0015850 29 14 0,000 0,04372227 0,0711263 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04372227 0,07107824 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04372227 0,07103024 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04372227 0,07098231 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04372227 0,07093445 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04372227 0,07088665 ! L-amino acid transport GO:0015807 30 14 0,000 0,04372227 0,07083892 ! bone mineralization GO:0030282 17 14 0,000 0,04372227 0,07079125 ! stem cell development GO:0048864 43 14 0,000 0,04372227 0,07074364 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04372227 0,0706961 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04372227 0,07064862 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04372227 0,0706012 ! cerebellum development GO:0021549 21 14 0,000 0,04372227 0,07055385 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04372227 0,07050656 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04372227 0,07045934 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04372227 0,07041218 ! cofactor transport GO:0051181 26 14 0,000 0,04372227 0,07036508 ! NADP metabolic process GO:0006739 24 14 0,000 0,04372227 0,07031804 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04372227 0,07027107 ! intestinal absorption GO:0050892 25 14 0,000 0,04372227 0,07022416 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04372227 0,07017731 ! oxygen transport GO:0015671 21 14 0,000 0,04372227 0,07013053 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04372227 0,0700838 ! male genitalia development GO:0030539 24 14 0,000 0,04372227 0,07003714 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04372227 0,06999055 ! regulation of axon extension GO:0030516 37 14 0,000 0,04372227 0,06994401 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04372227 0,06989754 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04677189 0,07472322 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04677189 0,07467364 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04677189 0,07462412 ! superoxide anion generation GO:0042554 20 15 0,000 0,04677189 0,07457467 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04677189 0,07452528 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04677189 0,07447596 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04677189 0,0744267 ! copper ion transport GO:0006825 20 15 0,000 0,04677189 0,07437751 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04677189 0,07432838 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04677189 0,07427932 ! sulfate transport GO:0008272 23 15 0,000 0,04677189 0,07423032 ! response to cAMP GO:0051591 22 15 0,000 0,04677189 0,07418139 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04677189 0,07413252 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04677189 0,07408372 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04677189 0,07403498 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04677189 0,07398631 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04677189 0,0739377 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04677189 0,07388915 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04677189 0,07384066 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04677189 0,07379224 ! pituitary gland development GO:0021983 29 15 0,000 0,04677189 0,07374389 ! vesicle coating GO:0006901 33 15 0,000 0,04677189 0,07369559 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04677189 0,07364736 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04677189 0,0735992 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04677189 0,07355109 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04677189 0,07350305 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04677189 0,07345507 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04677189 0,07340716 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04677189 0,0733593 ! histone deacetylation GO:0016575 20 15 0,000 0,04677189 0,07331151 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04677189 0,07326378 ! tissue regeneration GO:0042246 26 15 0,000 0,04677189 0,07321612 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04677189 0,07316851 ! water homeostasis GO:0030104 27 15 0,000 0,04677189 0,07312097 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04677189 0,07307349 ! muscle maintenance GO:0046716 26 15 0,000 0,04677189 0,07302607 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04677189 0,07297871 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04677189 0,07293141 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04677189 0,07288418 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04677189 0,072837 ! cell killing GO:0001906 29 15 0,000 0,04677189 0,07278989 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04677189 0,07274284 ! detection of bacterium GO:0016045 18 15 0,000 0,04677189 0,07269585 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04677189 0,07264892 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04677189 0,07260205 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04677189 0,07255524 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04677189 0,07250849 ! peptide hormone processing GO:0016486 23 15 0,000 0,04677189 0,0724618 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04981189 0,07712188 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04981189 0,07707228 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04981189 0,07702275 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04981189 0,07697328 ! bone remodeling GO:0046849 27 16 0,000 0,04981189 0,07692388 ! filopodium assembly GO:0046847 32 16 0,000 0,04981189 0,07687453 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04981189 0,07682526 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04981189 0,07677604 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04981189 0,07672689 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04981189 0,0766778 ! startle response GO:0001964 28 16 0,000 0,04981189 0,07662877 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04981189 0,07657981 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04981189 0,07653091 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04981189 0,07648207 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04981189 0,07643329 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04981189 0,07638457 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04981189 0,07633592 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04981189 0,07628733 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04981189 0,0762388 ! response to osmotic stress GO:0006970 25 16 0,000 0,04981189 0,07619034 ! lysosomal transport GO:0007041 26 16 0,000 0,04981189 0,07614193 ! fructose metabolic process GO:0006000 25 16 0,000 0,04981189 0,07609359 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04981189 0,0760453 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04981189 0,07599708 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04981189 0,07594892 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04981189 0,07590082 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04981189 0,07585278 ! axon cargo transport GO:0008088 43 16 0,000 0,04981189 0,07580481 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04981189 0,07575689 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04981189 0,07570903 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04981189 0,07566124 ! DNA replication initiation GO:0006270 27 16 0,000 0,04981189 0,0756135 ! neuron recognition GO:0008038 35 16 0,000 0,04981189 0,07556582 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04981189 0,07551821 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04981189 0,07547065 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04981189 0,07542316 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04981189 0,07537572 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04981189 0,07532835 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04981189 0,07528103 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04981189 0,07523377 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04981189 0,07518657 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04981189 0,07513943 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04981189 0,07509235 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04981189 0,07504533 ! defense response to virus GO:0051607 37 16 0,000 0,04981189 0,07499837 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05284229 0,07951128 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05284229 0,07946159 ! metencephalon development GO:0022037 30 17 0,000 0,05284229 0,07941195 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05284229 0,07936238 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05284229 0,07931288 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05284229 0,07926343 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05284229 0,07921404 ! signal complex assembly GO:0007172 41 17 0,000 0,05284229 0,07916472 ! endothelial cell migration GO:0043542 28 17 0,000 0,05284229 0,07911546 ! inositol metabolic process GO:0006020 28 17 0,000 0,05284229 0,07906626 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05284229 0,07901712 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05284229 0,07896804 ! glial cell development GO:0021782 27 17 0,000 0,05284229 0,07891902 ! limbic system development GO:0021761 36 17 0,000 0,05284229 0,07887006 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05284229 0,07882117 ! adult walking behavior GO:0007628 33 17 0,000 0,05284229 0,07877233 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05284229 0,07872355 ! heart looping GO:0001947 30 17 0,000 0,05284229 0,07867484 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05284229 0,07862618 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05284229 0,07857759 ! myoblast differentiation GO:0045445 45 17 0,000 0,05284229 0,07852905 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05284229 0,07848058 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05284229 0,07843216 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05284229 0,07838381 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05284229 0,07833551 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05284229 0,07828728 ! glycine metabolic process GO:0006544 28 17 0,000 0,05284229 0,0782391 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05284229 0,07819098 ! NAD metabolic process GO:0019674 29 17 0,000 0,05284229 0,07814293 ! membrane budding GO:0006900 37 17 0,000 0,05284229 0,07809493 ! DNA integration GO:0015074 29 17 0,000 0,05284229 0,07804699 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05284229 0,0779991 ! regulation of protein binding GO:0043393 33 17 0,000 0,05284229 0,07795128 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05284229 0,07790352 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05284229 0,07785581 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05284229 0,07780816 ! genitalia development GO:0048806 30 17 0,000 0,05284229 0,07776057 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05284229 0,07771304 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05284229 0,07766557 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05284229 0,07761816 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05284229 0,0775708 ! steroid catabolic process GO:0006706 31 17 0,000 0,05284229 0,0775235 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05284229 0,07747626 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05284229 0,07742907 ! gas transport GO:0015669 25 17 0,000 0,05284229 0,07738195 ! organic cation transport GO:0015695 31 17 0,000 0,05284229 0,07733488 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05284229 0,07728787 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05284229 0,07724091 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05284229 0,07719401 ! microspike assembly GO:0030035 36 17 0,000 0,05284229 0,07714717 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05284229 0,07710039 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05586312 0,08145859 ! neuron maturation GO:0042551 42 18 0,000 0,05586312 0,08140925 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05586312 0,08135997 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05586312 0,08131075 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05586312 0,08126159 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05586312 0,08121249 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05586312 0,08116345 ! memory GO:0007613 31 18 0,000 0,05586312 0,08111447 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05586312 0,08106554 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05586312 0,08101668 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05586312 0,08096787 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05586312 0,08091913 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05586312 0,08087044 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05586312 0,08082181 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05586312 0,08077324 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05586312 0,08072473 ! response to retinoic acid GO:0032526 26 18 0,000 0,05586312 0,08067627 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05586312 0,08062788 ! response to fungus GO:0009620 21 18 0,000 0,05586312 0,08057954 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05586312 0,08053126 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05586312 0,08048304 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05586312 0,08043487 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05586312 0,08038676 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05586312 0,08033871 ! vitamin transport GO:0051180 27 18 0,000 0,05586312 0,08029072 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05586312 0,08024279 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05586312 0,08019491 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05586312 0,08014709 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05586312 0,08009933 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05586312 0,08005162 ! nerve development GO:0021675 28 18 0,000 0,05586312 0,08000397 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05586312 0,07995638 ! protein secretion GO:0009306 39 19 0,000 0,05887442 0,08421632 ! positive regulation of translation GO:0045727 30 19 0,000 0,05887442 0,08416629 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05887442 0,08411631 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05887442 0,08406638 ! skin development GO:0043588 36 19 0,000 0,05887442 0,08401652 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05887442 0,08396672 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05887442 0,08391698 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05887442 0,08386729 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05887442 0,08381767 ! cerebral cortex development GO:0021987 36 19 0,000 0,05887442 0,0837681 ! pigmentation during development GO:0048066 41 19 0,000 0,05887442 0,08371859 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05887442 0,08366914 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05887442 0,08361975 ! heme metabolic process GO:0042168 36 19 0,000 0,05887442 0,08357042 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05887442 0,08352114 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05887442 0,08347193 ! peptide cross-linking GO:0018149 37 19 0,000 0,05887442 0,08342277 ! protein export from nucleus GO:0006611 36 19 0,000 0,05887442 0,08337367 ! heart process GO:0003015 30 19 0,000 0,05887442 0,08332462 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05887442 0,08327564 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05887442 0,08322671 ! visual learning GO:0008542 36 19 0,000 0,05887442 0,08317784 ! cellular pigmentation GO:0033059 36 19 0,000 0,05887442 0,08312902 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05887442 0,08308027 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05887442 0,08303157 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05887442 0,08298293 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05887442 0,08293434 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05887442 0,08288582 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05887442 0,08283734 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05887442 0,08278893 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05887442 0,08274057 ! cilium assembly GO:0042384 37 19 0,000 0,05887442 0,08269227 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05887442 0,08264402 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06187622 0,0868071 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06187622 0,08675651 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06187622 0,08670599 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06187622 0,08665552 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06187622 0,08660511 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,06187622 0,08655476 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06187622 0,08650446 ! response to vitamin GO:0033273 31 20 0,000 0,06187622 0,08645423 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06187622 0,08640405 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06187622 0,08635393 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06187622 0,08630387 ! response to alkaloid GO:0043279 38 20 0,000 0,06187622 0,08625387 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06187622 0,08620393 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06187622 0,08615404 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06187622 0,08610421 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06187622 0,08605444 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06187622 0,08600473 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06187622 0,08595507 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06187622 0,08590547 ! body fluid secretion GO:0007589 31 20 0,000 0,06187622 0,08585593 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06187622 0,08580644 ! peptide secretion GO:0002790 35 20 0,000 0,06187622 0,08575702 ! stem cell differentiation GO:0048863 53 20 0,000 0,06187622 0,08570765 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06187622 0,08565833 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06187622 0,08560907 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06187622 0,08555987 ! sensory perception of pain GO:0019233 30 20 0,000 0,06187622 0,08551073 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06187622 0,08546164 ! diencephalon development GO:0021536 34 20 0,000 0,06187622 0,08541261 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06187622 0,08536364 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06187622 0,08531472 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06187622 0,08526585 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06187622 0,08521705 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06187622 0,0851683 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06187622 0,0851196 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06187622 0,08507096 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06187622 0,08502238 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06187622 0,08497385 ! actin filament-based movement GO:0030048 43 20 0,000 0,06187622 0,08492537 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06187622 0,08487696 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06187622 0,08482859 ! regulation of cell killing GO:0031341 42 21 0,000 0,06486854 0,08888024 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06486854 0,08882966 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06486854 0,08877913 ! hormone secretion GO:0046879 38 21 0,000 0,06486854 0,08872865 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06486854 0,08867824 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06486854 0,08862788 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06486854 0,08857758 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06486854 0,08852734 ! axis specification GO:0009798 38 21 0,000 0,06486854 0,08847716 ! ovarian follicle development GO:0001541 35 21 0,000 0,06486854 0,08842703 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06486854 0,08837696 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06486854 0,08832694 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06486854 0,08827698 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06486854 0,08822708 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06486854 0,08817723 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06486854 0,08812744 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06486854 0,08807771 ! cytolysis GO:0019835 24 21 0,000 0,06486854 0,08802803 ! vasodilation GO:0042311 39 21 0,000 0,06486854 0,08797841 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06486854 0,08792885 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06486854 0,08787934 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06486854 0,08782988 ! oogenesis GO:0048477 36 21 0,000 0,06486854 0,08778049 ! DNA modification GO:0006304 34 21 0,000 0,06486854 0,08773114 ! collagen fibril organization GO:0030199 59 21 0,000 0,06486854 0,08768186 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06486854 0,08763262 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06486854 0,08758345 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06486854 0,08753433 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06486854 0,08748526 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06486854 0,08743625 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06486854 0,08738729 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06486854 0,08733839 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06486854 0,08728954 ! collagen catabolic process GO:0030574 28 21 0,000 0,06486854 0,08724075 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06486854 0,08719201 ! gut development GO:0048565 39 21 0,000 0,06486854 0,08714333 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06785141 0,09109961 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06785141 0,0910488 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06785141 0,09099805 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06785141 0,09094736 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06785141 0,09089672 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06785141 0,09084613 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06785141 0,09079561 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06785141 0,09074514 ! regeneration GO:0031099 41 22 0,000 0,06785141 0,09069472 ! keratinization GO:0031424 28 22 0,000 0,06785141 0,09064437 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06785141 0,09059406 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06785141 0,09054382 ! sensory perception of taste GO:0050909 28 22 0,000 0,06785141 0,09049363 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06785141 0,09044349 ! vacuolar transport GO:0007034 36 22 0,000 0,06785141 0,09039341 ! lysosome organization GO:0007040 41 22 0,000 0,06785141 0,09034339 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06785141 0,09029342 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06785141 0,09024351 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06785141 0,09019365 ! fucose metabolic process GO:0006004 39 22 0,000 0,06785141 0,09014384 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06785141 0,0900941 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06785141 0,0900444 ! ureteric bud development GO:0001657 43 22 0,000 0,06785141 0,08999476 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06785141 0,08994518 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06785141 0,08989565 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06785141 0,08984618 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06785141 0,08979676 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06785141 0,08974739 ! sarcomere organization GO:0045214 30 22 0,000 0,06785141 0,08969808 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06785141 0,08964882 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06785141 0,08959962 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06785141 0,08955047 ! protein stabilization GO:0050821 39 22 0,000 0,06785141 0,08950137 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07082487 0,09337241 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,07082487 0,09332127 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07082487 0,09327019 ! gluconeogenesis GO:0006094 33 23 0,000 0,07082487 0,09321917 ! viral genome replication GO:0019079 41 23 0,000 0,07082487 0,0931682 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07082487 0,09311729 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07082487 0,09306644 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07082487 0,09301564 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07082487 0,09296489 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07082487 0,0929142 ! visual behavior GO:0007632 42 23 0,000 0,07082487 0,09286357 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07082487 0,09281299 ! response to ethanol GO:0045471 46 23 0,000 0,07082487 0,09276246 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07082487 0,09271199 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07082487 0,09266158 ! peroxisome organization GO:0007031 37 23 0,000 0,07082487 0,09261122 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07082487 0,09256092 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07082487 0,09251067 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07082487 0,09246047 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07082487 0,09241033 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07082487 0,09236024 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07082487 0,09231021 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07082487 0,09226023 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07082487 0,09221031 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07082487 0,09216044 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07082487 0,09211062 ! fatty acid transport GO:0015908 44 23 0,000 0,07082487 0,09206086 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07082487 0,09201115 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07082487 0,09196149 ! hormone transport GO:0009914 40 23 0,000 0,07082487 0,09191189 ! cell-cell recognition GO:0009988 25 23 0,000 0,07082487 0,09186234 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07082487 0,09181285 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07082487 0,09176341 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,07082487 0,09171402 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07082487 0,09166468 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07082487 0,0916154 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07378895 0,09539828 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07378895 0,09534705 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07378895 0,09529587 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07378895 0,09524475 ! vesicle docking GO:0048278 47 24 0,000 0,07378895 0,09519368 ! spinal cord development GO:0021510 47 24 0,000 0,07378895 0,09514266 ! vacuole organization GO:0007033 43 24 0,000 0,07378895 0,0950917 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07378895 0,0950408 ! digestive system process GO:0022600 39 24 0,000 0,07378895 0,09498994 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07378895 0,09493915 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07378895 0,0948884 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07378895 0,09483772 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07378895 0,09478708 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07378895 0,0947365 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07378895 0,09468598 ! membrane depolarization GO:0051899 39 24 0,000 0,07378895 0,0946355 ! pallium development GO:0021543 49 24 0,000 0,07378895 0,09458509 ! pentose metabolic process GO:0019321 35 24 0,000 0,07378895 0,09453472 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07378895 0,09448441 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07378895 0,09443415 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07378895 0,09438395 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07378895 0,0943338 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07378895 0,0942837 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07378895 0,09423365 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07378895 0,09418366 ! regulation of amine transport GO:0051952 40 24 0,000 0,07378895 0,09413373 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07674366 0,09785122 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07674366 0,09779939 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07674366 0,09774762 ! phototransduction GO:0007602 33 25 0,000 0,07674366 0,0976959 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07674366 0,09764424 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,07674366 0,09759263 ! sperm motility GO:0030317 31 25 0,000 0,07674366 0,09754107 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07674366 0,09748957 ! receptor metabolic process GO:0043112 46 25 0,000 0,07674366 0,09743813 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07674366 0,09738674 ! neural crest cell development GO:0014032 54 25 0,000 0,07674366 0,0973354 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07674366 0,09728412 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07674366 0,09723289 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07674366 0,09718171 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07674366 0,09713059 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07674366 0,09707952 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,07674366 0,09702851 ! immunoglobulin production GO:0002377 55 25 0,000 0,07674366 0,09697755 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07674366 0,09692664 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07674366 0,09687579 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07674366 0,09682499 ! telomere organization GO:0032200 43 25 0,000 0,07674366 0,09677424 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07674366 0,09672355 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07674366 0,09667291 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07968905 0,10033064 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07968905 0,10027817 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07968905 0,10022575 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07968905 0,10017338 ! initiation of viral infection GO:0019059 57 26 0,000 0,07968905 0,10012107 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07968905 0,10006882 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07968905 0,10001662 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07968905 0,09996447 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07968905 0,09991238 ! molting cycle process GO:0022404 50 26 0,000 0,07968905 0,09986034 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07968905 0,09980836 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07968905 0,09975643 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,07968905 0,09970455 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07968905 0,09965273 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07968905 0,09960096 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07968905 0,09954925 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07968905 0,09949759 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07968905 0,09944598 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07968905 0,09939443 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07968905 0,09934293 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07968905 0,09929148 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07968905 0,09924009 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07968905 0,09918875 ! blastocyst development GO:0001824 49 26 0,000 0,07968905 0,09913746 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07968905 0,09908623 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07968905 0,09903505 ! neuron fate commitment GO:0048663 48 27 0,000 0,08262514 0,10263092 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,08262514 0,10257796 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,08262514 0,10252506 ! iron ion transport GO:0006826 59 27 0,000 0,08262514 0,10247221 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08262514 0,10241941 ! protein amino acid acylation GO:0043543 55 27 0,000 0,08262514 0,10236668 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08262514 0,10231399 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08262514 0,10226136 ! fat cell differentiation GO:0045444 50 27 0,000 0,08262514 0,10220878 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08262514 0,10215626 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08262514 0,10210379 ! autophagy GO:0006914 41 27 0,000 0,08262514 0,10205138 ! male gonad development GO:0008584 44 27 0,000 0,08262514 0,10199902 ! response to toxin GO:0009636 47 27 0,000 0,08262514 0,10194671 ! primary neural tube formation GO:0014020 51 27 0,000 0,08262514 0,10189446 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08262514 0,10184226 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08262514 0,10179011 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,08262514 0,10173802 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08262514 0,10168598 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08262514 0,10163399 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,08262514 0,10158206 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08262514 0,10153018 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08555196 0,105073 ! circadian rhythm GO:0007623 50 28 0,000 0,08555196 0,10501939 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08555196 0,10496584 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08555196 0,10491234 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08555196 0,1048589 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08555196 0,1048055 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08555196 0,10475217 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08555196 0,10469889 ! synaptogenesis GO:0007416 42 28 0,000 0,08555196 0,10464566 ! lipid oxidation GO:0034440 43 28 0,000 0,08555196 0,10459249 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08555196 0,10453937 ! translational initiation GO:0006413 65 29 0,000 0,08846954 0,1080496 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08846954 0,10799478 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08846954 0,10794001 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08846954 0,1078853 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08846954 0,10783065 ! catechol metabolic process GO:0009712 54 29 0,000 0,08846954 0,10777605 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08846954 0,10772151 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08846954 0,10766702 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08846954 0,10761259 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08846954 0,10755821 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08846954 0,10750389 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08846954 0,10744962 ! cell fate determination GO:0001709 60 29 0,000 0,08846954 0,10739541 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08846954 0,10734125 ! detection of light stimulus GO:0009583 38 29 0,000 0,08846954 0,10728715 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08846954 0,1072331 ! tissue homeostasis GO:0001894 48 29 0,000 0,08846954 0,10717911 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,0913779 0,11064682 ! zinc ion transport GO:0006829 45 30 0,000 0,0913779 0,11059116 ! membrane docking GO:0022406 61 30 0,000 0,0913779 0,11053556 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,0913779 0,11048002 ! regulation of innate immune response GO:0045088 51 30 0,000 0,0913779 0,11042453 ! acute-phase response GO:0006953 49 30 0,000 0,0913779 0,11036909 ! myofibril assembly GO:0030239 47 30 0,000 0,0913779 0,11031371 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,0913779 0,11025839 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,0913779 0,11020312 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,0913779 0,11014791 ! phospholipid transport GO:0015914 51 30 0,000 0,0913779 0,11009276 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,0913779 0,11003765 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,0913779 0,10998261 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,0913779 0,10992762 ! eye morphogenesis GO:0048592 60 30 0,000 0,0913779 0,10987268 ! response to heat GO:0009408 50 30 0,000 0,0913779 0,1098178 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09427709 0,11324547 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09427709 0,11318896 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09427709 0,1131325 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09427709 0,11307611 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09427709 0,11301976 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09427709 0,11296348 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09427709 0,11290725 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09427709 0,11285108 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09427709 0,11279496 ! ovulation cycle process GO:0022602 49 31 0,000 0,09427709 0,1127389 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09427709 0,1126829 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09427709 0,11262695 ! peptide transport GO:0015833 55 31 0,000 0,09427709 0,11257105 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09427709 0,11251521 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09427709 0,11245943 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09427709 0,1124037 ! mesoderm formation GO:0001707 69 31 0,000 0,09427709 0,11234803 ! natural killer cell activation GO:0030101 45 31 0,000 0,09427709 0,11229241 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09427709 0,11223685 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09427709 0,11218134 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09427709 0,11212589 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,09427709 0,11207049 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09427709 0,11201514 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09716711 0,11539194 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09716711 0,11533502 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09716711 0,11527814 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09716711 0,11522133 ! cholesterol transport GO:0030301 56 32 0,000 0,09716711 0,11516457 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09716711 0,11510787 ! spliceosome assembly GO:0000245 67 32 0,000 0,09716711 0,11505122 ! spindle organization GO:0007051 46 32 0,000 0,09716711 0,11499463 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09716711 0,11493809 ! metanephros development GO:0001656 74 32 0,000 0,09716711 0,11488161 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09716711 0,11482519 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09716711 0,11476882 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09716711 0,1147125 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,09716711 0,11465624 ! muscle cell development GO:0055001 49 32 0,000 0,09716711 0,11460004 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09716711 0,11454389 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09716711 0,11448779 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09716711 0,11443176 ! ovulation cycle GO:0042698 51 32 0,000 0,09716711 0,11437577 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09716711 0,11431984 ! hindbrain development GO:0030902 61 32 0,000 0,09716711 0,11426397 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09716711 0,11420815 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09716711 0,11415238 ! gene silencing GO:0016458 65 32 0,000 0,09716711 0,11409667 ! post-embryonic development GO:0009791 69 33 0,000 0,10004802 0,11742221 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10004802 0,11736496 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10004802 0,11730776 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10004802 0,11725062 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10004802 0,11719354 ! sterol transport GO:0015918 57 33 0,000 0,10004802 0,11713651 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10004802 0,11707954 ! adult locomotory behavior GO:0008344 59 33 0,000 0,10004802 0,11702262 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,10004802 0,11696576 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10004802 0,11690895 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,10291982 0,12020636 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10291982 0,12014803 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,10291982 0,12008976 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10291982 0,12003155 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,10291982 0,1199734 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,10291982 0,1199153 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10291982 0,11985726 ! mismatch repair GO:0006298 46 34 0,000 0,10291982 0,11979927 ! spermatid development GO:0007286 63 34 0,000 0,10291982 0,11974134 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10291982 0,11968347 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10291982 0,11962565 ! placenta development GO:0001890 53 34 0,000 0,10291982 0,11956789 ! regulation of muscle development GO:0048634 70 35 0,000 0,10578256 0,12283438 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10578256 0,12277513 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,10578256 0,12271593 ! odontogenesis GO:0042476 66 35 0,000 0,10578256 0,12265679 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10578256 0,12259771 ! female gonad development GO:0008585 58 35 0,000 0,10578256 0,12253868 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10578256 0,12247971 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10578256 0,1224208 ! cytokine production GO:0001816 59 35 0,000 0,10578256 0,12236194 ! neural tube formation GO:0001841 67 35 0,000 0,10578256 0,12230314 ! vesicle localization GO:0051648 64 35 0,000 0,10578256 0,1222444 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,10863625 0,12548191 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10863625 0,1254217 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10863625 0,12536155 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10863625 0,12530145 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,10863625 0,12524141 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10863625 0,12518143 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10863625 0,12512151 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10863625 0,12506164 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10863625 0,12500183 ! aerobic respiration GO:0009060 55 36 0,000 0,10863625 0,12494208 ! embryonic organ development GO:0048568 57 36 0,000 0,10863625 0,12488238 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10863625 0,12482274 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11148094 0,12803014 ! meiosis I GO:0007127 65 37 0,000 0,11148094 0,12796905 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,11148094 0,12790803 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11148094 0,12784706 ! organic anion transport GO:0015711 68 37 0,000 0,11148094 0,12778615 ! tissue remodeling GO:0048771 76 37 0,000 0,11148094 0,1277253 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,11148094 0,12766451 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11148094 0,12760378 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11148094 0,1275431 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11148094 0,12748248 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,11148094 0,12742192 ! pigment metabolic process GO:0042440 80 37 0,000 0,11148094 0,12736141 ! spermatid differentiation GO:0048515 66 37 0,000 0,11148094 0,12730097 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11431664 0,13047715 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11431664 0,13041528 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11431664 0,13035347 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11431664 0,13029172 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11431664 0,13023003 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,11431664 0,1301684 ! lipid homeostasis GO:0055088 67 38 0,000 0,11431664 0,13010682 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11431664 0,13004531 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11431664 0,12998385 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11431664 0,12992245 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11431664 0,12986111 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11431664 0,12979982 ! mRNA catabolic process GO:0006402 71 39 0,000 0,11714338 0,13294668 ! learning GO:0007612 77 39 0,000 0,11714338 0,132884 ! ear morphogenesis GO:0042471 60 39 0,000 0,11714338 0,13282138 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11714338 0,13275882 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11714338 0,13269631 ! segmentation GO:0035282 67 39 0,000 0,11714338 0,13263387 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11714338 0,13257148 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11714338 0,13250915 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11714338 0,13244689 ! RNA modification GO:0009451 57 39 0,000 0,11714338 0,13238467 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11714338 0,13232252 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11996119 0,13544187 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,11996119 0,13537835 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11996119 0,13531488 ! feeding behavior GO:0007631 59 40 0,000 0,11996119 0,13525147 ! negative regulation of binding GO:0051100 72 40 0,000 0,11996119 0,13518812 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11996119 0,13512483 ! mesenchymal cell development GO:0014031 87 40 0,000 0,11996119 0,1350616 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11996119 0,13499843 ! maintenance of protein location GO:0045185 91 40 0,000 0,11996119 0,13493531 ! cytokinesis GO:0000910 72 40 0,000 0,11996119 0,13487226 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12277011 0,13796585 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,12277011 0,13790144 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,12277011 0,13783709 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,12277011 0,1377728 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,12277011 0,13770857 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,12277011 0,1376444 ! female gamete generation GO:0007292 61 41 0,000 0,12277011 0,13758029 ! polyol metabolic process GO:0019751 66 41 0,000 0,12277011 0,13751624 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,12277011 0,13745225 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,12557015 0,14052176 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,12557015 0,14045643 ! regulation of tube size GO:0035150 71 42 0,000 0,12557015 0,14039116 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,12557015 0,14032596 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12557015 0,14026081 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12557015 0,14019572 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12557015 0,1401307 ! neuron migration GO:0001764 79 42 0,000 0,12557015 0,14006573 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12836135 0,14311279 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12836135 0,14304651 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12836135 0,14298028 ! glucose transport GO:0015758 65 43 0,000 0,12836135 0,14291412 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12836135 0,14284801 ! neural tube development GO:0021915 77 43 0,000 0,12836135 0,14278197 ! striated muscle contraction GO:0006941 77 43 0,000 0,12836135 0,14271599 ! phagocytosis GO:0006909 90 43 0,000 0,12836135 0,14265007 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12836135 0,14258421 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,13114373 0,14560767 ! hexose transport GO:0008645 67 44 0,000 0,13114373 0,1455405 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,13114373 0,1454734 ! male sex differentiation GO:0046661 76 44 0,000 0,13114373 0,14540637 ! biopolymer methylation GO:0043414 84 44 0,000 0,13114373 0,14533939 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,13114373 0,14527247 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,13114373 0,14520562 ! developmental growth GO:0048589 82 44 0,000 0,13114373 0,14513883 ! maintenance of location in cell GO:0051651 97 44 0,000 0,13114373 0,1450721 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,13391732 0,14807218 ! glycolysis GO:0006096 65 45 0,000 0,13391732 0,14800417 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,13391732 0,14793621 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,13391732 0,14786832 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13391732 0,14780049 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13391732 0,14773272 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13391732 0,14766502 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,13391732 0,14759738 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13391732 0,1475298 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13668215 0,15050675 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,13668215 0,1504379 ! pigmentation GO:0043473 100 46 0,000 0,13668215 0,15036911 ! response to calcium ion GO:0051592 81 47 0,000 0,13943824 0,15333109 ! endosome transport GO:0016197 108 47 0,000 0,13943824 0,15326104 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,13943824 0,15319106 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,13943824 0,15312114 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13943824 0,15305128 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13943824 0,15298149 ! methylation GO:0032259 90 47 0,000 0,13943824 0,15291177 ! protein homooligomerization GO:0051260 76 47 0,000 0,13943824 0,1528421 ! Notch signaling pathway GO:0007219 96 48 0,000 0,14218563 0,15578262 ! cellular component disassembly GO:0022411 86 48 0,000 0,14218563 0,15571171 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,14218563 0,15564087 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14218563 0,15557009 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14218563 0,15549938 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,14492434 0,15842252 ! regulation of ion transport GO:0043269 77 49 0,000 0,14492434 0,15835057 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14492434 0,15827869 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,14492434 0,15820688 ! endocrine system development GO:0035270 104 49 0,000 0,14492434 0,15813513 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,14492434 0,15806344 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,14492434 0,15799182 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14492434 0,15792027 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,14492434 0,15784878 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,14765439 0,16074953 ! neuromuscular process GO:0050905 99 50 0,000 0,14765439 0,16067683 ! inner ear development GO:0048839 79 50 0,000 0,14765439 0,16060419 ! histone modification GO:0016570 91 50 0,000 0,14765439 0,16053162 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14765439 0,16045911 ! positive regulation of binding GO:0051099 78 51 0,000 0,15037582 0,16334276 ! viral infectious cycle GO:0019058 99 51 0,000 0,15037582 0,16326905 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,15037582 0,16319541 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,15037582 0,16312183 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,15037582 0,16304832 ! excretion GO:0007588 83 51 0,000 0,15037582 0,16297488 ! chromatin remodeling GO:0006338 109 51 0,000 0,15037582 0,1629015 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,15037582 0,16282818 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,15037582 0,16275494 ! vesicle organization GO:0016050 107 51 0,000 0,15037582 0,16268175 ! regulation of cell shape GO:0008360 125 51 0,000 0,15037582 0,16260864 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,15037582 0,16253559 ! covalent chromatin modification GO:0016569 101 52 0,000 0,15308865 0,16539348 ! amino acid activation GO:0043038 92 52 0,000 0,15308865 0,16531925 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,15579291 0,16816408 ! RNA catabolic process GO:0006401 93 53 0,000 0,15579291 0,16808867 ! regulation of translational initiation GO:0006446 82 53 0,000 0,15579291 0,16801333 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,15579291 0,16793805 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,15579291 0,16786284 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,15579291 0,1677877 ! cell maturation GO:0048469 100 53 0,000 0,15579291 0,16771263 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,15579291 0,16763763 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,15848862 0,17046205 ! cell recognition GO:0008037 85 54 0,000 0,15848862 0,17038589 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15848862 0,17030979 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15848862 0,17023376 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15848862 0,17015779 ! chloride transport GO:0006821 90 55 0,000 0,16117581 0,17296566 ! glucose catabolic process GO:0006007 82 55 0,000 0,16117581 0,17288854 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,16117581 0,1728115 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,16117581 0,17273452 ! gastrulation GO:0007369 112 55 0,000 0,16117581 0,17265761 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,16117581 0,17258078 ! nuclear export GO:0051168 97 55 0,000 0,16117581 0,172504 ! regulation of actin filament length GO:0030832 105 56 0,000 0,16385451 0,175293 ! sensory perception of smell GO:0007608 80 56 0,000 0,16385451 0,17521509 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,16385451 0,17513725 ! proton transport GO:0015992 94 56 0,000 0,16385451 0,17505948 ! maintenance of location GO:0051235 118 57 0,000 0,16652475 0,17783335 ! hydrogen transport GO:0006818 97 58 0,000 0,16918655 0,18059575 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16918655 0,18051567 ! adult behavior GO:0030534 99 58 0,000 0,16918655 0,18043565 ! positive regulation of secretion GO:0051047 95 59 0,000 0,17183993 0,18318426 ! regulation of cellular component size GO:0032535 109 59 0,000 0,17183993 0,18310313 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,17183993 0,18302208 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,17183993 0,18294109 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,17183993 0,18286018 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,17183993 0,18277934 ! establishment of organelle localization GO:0051656 109 59 0,000 0,17183993 0,18269857 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,17448493 0,18542877 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,17448493 0,18534691 ! camera-type eye development GO:0043010 116 60 0,000 0,17448493 0,18526511 ! kidney development GO:0001822 122 60 0,000 0,17448493 0,18518339 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,17712157 0,18789881 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,17712157 0,18781599 ! mesoderm development GO:0007498 119 61 0,000 0,17712157 0,18773326 ! tRNA processing GO:0008033 89 61 0,000 0,17712157 0,18765059 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,17712157 0,187568 ! ear development GO:0043583 103 62 0,000 0,17974987 0,19026757 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17974987 0,1901839 ! gonad development GO:0008406 98 62 0,000 0,17974987 0,1901003 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,18236987 0,19278643 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,18236987 0,19270176 ! detection of external stimulus GO:0009581 91 63 0,000 0,18236987 0,19261717 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,18236987 0,19253265 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,18498159 0,19520425 ! cell redox homeostasis GO:0045454 102 64 0,000 0,18498159 0,19511867 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,18498159 0,19503317 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,18498159 0,19494774 GO:0048609|reproductive process in a multicellular organism, ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18758504 0,19760491 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18758504 0,19751843 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,18758504 0,19743203 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,18758504 0,1973457 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,18758504 0,19725945 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,19018027 0,19990115 ! actin filament organization GO:0007015 148 66 0,000 0,19018027 0,19981386 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,19018027 0,19972664 ! extracellular matrix organization GO:0030198 133 66 0,000 0,19018027 0,1996395 ! secondary metabolic process GO:0019748 116 66 0,000 0,19018027 0,19955244 ! developmental maturation GO:0021700 116 66 0,000 0,19018027 0,19946545 ! cell projection assembly GO:0030031 120 66 0,000 0,19018027 0,19937854 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,1927673 0,20200267 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,1927673 0,20191472 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,1927673 0,20182686 ! hexose catabolic process GO:0019320 104 67 0,000 0,1927673 0,20173907 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,1927673 0,20165136 ! adaptive immune response GO:0002250 119 67 0,000 0,1927673 0,20156372 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,1927673 0,20147616 ! amino acid transport GO:0006865 125 68 0,000 0,19534615 0,20408286 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,19534615 0,20399428 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,19534615 0,20390578 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,19534615 0,20381736 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,19791684 0,20641002 ! urogenital system development GO:0001655 137 69 0,000 0,19791684 0,20632059 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19791684 0,20623123 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19791684 0,20614195 ! antigen processing and presentation GO:0019882 104 69 0,000 0,19791684 0,20605275 ! appendage morphogenesis GO:0035107 135 70 0,000 0,20047941 0,20863038 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,20303387 0,21119736 ! reproductive structure development GO:0048608 113 71 0,000 0,20303387 0,21110609 ! appendage development GO:0048736 136 71 0,000 0,20303387 0,2110149 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,20303387 0,21092379 ! regulation of immune effector process GO:0002697 137 71 0,000 0,20303387 0,21083275 ! acute inflammatory response GO:0002526 113 72 0,000 0,20558026 0,21338486 ! carbohydrate transport GO:0008643 110 72 0,000 0,20558026 0,21329284 ! learning or memory GO:0007611 147 73 0,000 0,20811859 0,21583333 ! regulation of blood pressure GO:0008217 125 73 0,000 0,20811859 0,21574034 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,20811859 0,21564743 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,2106489 0,21817532 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,2106489 0,21808144 ! neurotransmitter transport GO:0006836 123 74 0,000 0,2106489 0,21798764 ! meiosis GO:0007126 121 74 0,000 0,2106489 0,21789392 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,2106489 0,21780028 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,2106489 0,21770673 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,2106489 0,21761325 ! eye development GO:0001654 143 74 0,000 0,2106489 0,21751985 ! organelle localization GO:0051640 136 74 0,000 0,2106489 0,21742654 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,21317121 0,21993565 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,21317121 0,21984138 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,21317121 0,21974719 ! meiotic cell cycle GO:0051321 122 75 0,000 0,21317121 0,21965308 ! rhythmic process GO:0048511 128 75 0,000 0,21317121 0,21955905 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,21568554 0,22205366 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,21568554 0,22195869 ! defense response to bacterium GO:0042742 89 76 0,000 0,21568554 0,22186379 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,21568554 0,22176898 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,21568554 0,22167425 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,21819192 0,22415447 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,21819192 0,2240588 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,22069038 0,22652775 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,22318093 0,22898649 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,22318093 0,22888888 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,22318093 0,22879136 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,22566361 0,23123792 ! response to metal ion GO:0010038 140 80 0,000 0,22566361 0,23113948 ! muscle cell differentiation GO:0042692 159 80 0,000 0,22566361 0,23104112 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,22566361 0,23094285 ! inorganic anion transport GO:0015698 138 80 0,000 0,22566361 0,23084466 ! digestion GO:0007586 112 81 0,000 0,22813843 0,23327712 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,22813843 0,23317802 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,22813843 0,23307901 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,22813843 0,23298008 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,23060543 0,23539952 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,23060543 0,23529969 ! response to nutrient GO:0007584 125 82 0,000 0,23060543 0,23519994 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,23060543 0,23510028 ! regulation of lyase activity GO:0051339 160 83 0,000 0,23306462 0,23750677 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,23551604 0,23990329 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,23551604 0,23980177 ! response to unfolded protein GO:0006986 131 85 0,000 0,2379597 0,24218741 ! nucleosome assembly GO:0006334 122 85 0,000 0,2379597 0,242085 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,2379597 0,24198268 ! amine biosynthetic process GO:0009309 138 86 0,000 0,24039563 0,24435652 ! response to inorganic substance GO:0010035 153 86 0,000 0,24039563 0,24425333 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,24039563 0,24415022 ! chromatin assembly GO:0031497 124 86 0,000 0,24039563 0,24404721 ! alcohol catabolic process GO:0046164 130 86 0,000 0,24039563 0,24394428 ! amine transport GO:0015837 155 86 0,000 0,24039563 0,24384143 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,24282385 0,24620067 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,24282385 0,24609696 ! cellular respiration GO:0045333 135 88 0,000 0,2452444 0,24844548 ! regulation of DNA binding GO:0051101 155 88 0,000 0,2452444 0,24834092 ! regulation of neurological system process GO:0031644 148 88 0,000 0,2452444 0,24823644 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,2452444 0,24813205 ! cellular defense response GO:0006968 114 89 0,000 0,24765728 0,25046802 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,24765728 0,25036278 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,25006253 0,25268814 ! sex differentiation GO:0007548 145 90 0,000 0,25006253 0,25258205 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,25006253 0,25247606 ! sterol metabolic process GO:0016125 152 91 0,000 0,25246017 0,25478992 ! response to protein stimulus GO:0051789 149 91 0,000 0,25246017 0,25468309 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,25246017 0,25457635 ! nucleosome organization GO:0034728 138 92 0,000 0,25485023 0,25687878 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,25485023 0,25677121 ! vitamin metabolic process GO:0006766 139 92 0,000 0,25485023 0,25666373 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,25723272 0,25895478 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,25723272 0,25884648 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,25960768 0,26112712 ! female pregnancy GO:0007565 164 94 0,000 0,25960768 0,261018 ! forebrain development GO:0030900 188 95 0,000 0,26197512 0,26328828 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,26433507 0,26554913 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,26433507 0,2654383 ! positive regulation of immune response GO:0050778 156 96 0,000 0,26433507 0,26532757 ! detection of stimulus GO:0051606 151 96 0,000 0,26433507 0,26521692 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,26668755 0,26746571 ! protein ubiquitination GO:0016567 217 97 0,000 0,26668755 0,26735427 ! hormone metabolic process GO:0042445 157 97 0,000 0,26668755 0,26724292 ! response to virus GO:0009615 160 98 0,000 0,26903259 0,2694806 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,26903259 0,26936846 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,26903259 0,26925641 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,2713702 0,27148304 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,2713702 0,2713702