pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6604-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of MAP kinase activity GO:0043406 174 93 6,000 1,153E-08 2,817E-05 ! positive regulation of phosphorylation GO:0042327 149 81 5,000 1,473E-07 1,8E-04 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 5,000 1,705E-07 1,389E-04 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of epithelial cell proliferation GO:0050678 122 45 4,000 2,166E-07 1,323E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 2,166E-07 1,058E-04 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 3,000 7,024E-07 2,86E-04 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 7,024E-07 2,452E-04 ! regulation of granule cell precursor proliferation GO:0021936 12 7 2,000 8,444E-07 2,579E-04 GO:0021940|positive regulation of granule cell precursor proliferation, ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 8,444E-07 2,292E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 9,838E-07 2,404E-04 GO:0045936|negative regulation of phosphate metabolic process, ! insulin receptor signaling pathway GO:0008286 66 27 3,000 1,152E-06 2,559E-04 ! regulation of fibroblast proliferation GO:0048145 56 28 3,000 1,341E-06 2,731E-04 ! ER overload response GO:0006983 13 8 2,000 1,348E-06 2,534E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,348E-06 2,353E-04 ! activation of MAPK activity GO:0000187 124 67 4,000 1,627E-06 2,65E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 4,000 1,885E-06 2,878E-04 ! induction of positive chemotaxis GO:0050930 17 9 2,000 2,018E-06 2,9E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 2,877E-06 3,904E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 3,947E-06 5,075E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 3,947E-06 4,821E-04 GO:0010829|negative regulation of glucose transport, ! cellular response to insulin stimulus GO:0032869 85 38 3,000 4,728E-06 5,501E-04 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 5,252E-06 5,832E-04 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 8,652E-06 9,19E-04 ! regulation of gene-specific transcription GO:0032583 102 46 3,000 1,027E-05 1,045E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 1,079E-05 1,055E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 1,12E-05 1,052E-03 ! activation of MAPKK activity GO:0000186 43 17 2,000 1,606E-05 1,453E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 1,606E-05 1,401E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,923E-05 1,62E-03 ! response to UV GO:0009411 120 55 3,000 2,103E-05 1,712E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 2,425E-05 1,911E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 2,598E-05 1,984E-03 ! regulation of glucose import GO:0046324 30 20 2,000 2,675E-05 1,981E-03 GO:0010827|regulation of glucose transport, ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 3,115E-05 2,238E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 3,115E-05 2,174E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 3,599E-05 2,442E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 3,599E-05 2,376E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 3,839E-05 2,468E-03 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 3,839E-05 2,405E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 4,082E-05 2,493E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 4,13E-05 2,461E-03 ! positive regulation of cell adhesion GO:0045785 61 24 2,000 4,71E-05 2,739E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 5,165E-05 2,935E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 5,34E-05 2,965E-03 ! regulation of behavior GO:0050795 48 25 2,000 5,34E-05 2,899E-03 ! protein tetramerization GO:0051262 57 25 2,000 5,34E-05 2,836E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 5,466E-05 2,841E-03 ! myelination GO:0042552 50 26 2,000 6,024E-05 3,066E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 6,024E-05 3,003E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 6,798E-05 3,322E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 6,798E-05 3,256E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 7,558E-05 3,551E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 7,558E-05 3,484E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 8,412E-05 3,806E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 8,412E-05 3,737E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 1,000 8,431E-05 3,678E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 8,431E-05 3,613E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 8,431E-05 3,551E-03 ! muscle cell migration GO:0014812 8 5 1,000 8,431E-05 3,491E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 8,431E-05 3,433E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 8,431E-05 3,376E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 8,431E-05 3,322E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 1,03E-04 3,996E-03 ! ensheathment of neurons GO:0007272 64 31 2,000 1,03E-04 3,933E-03 GO:0008366|axon ensheathment, ! negative regulation of transport GO:0051051 164 85 3,000 1,167E-04 4,387E-03 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 1,167E-04 4,32E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 1,245E-04 4,541E-03 GO:0060326|cell chemotaxis, ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 1,262E-04 4,535E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,262E-04 4,469E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 1,363E-04 4,757E-03 ! positive regulation of protein modification process GO:0031401 156 90 3,000 1,457E-04 5,012E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 1,764E-04 5,984E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,764E-04 5,902E-03 ! male sex determination GO:0030238 15 7 1,000 1,764E-04 5,822E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 1,764E-04 5,745E-03 ! fibrinolysis GO:0042730 11 7 1,000 1,764E-04 5,669E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,764E-04 5,596E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,764E-04 5,524E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 2,023E-04 6,254E-03 ! regulation of action potential in neuron GO:0019228 80 40 2,000 2,222E-04 6,786E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,347E-04 7,079E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 2,347E-04 6,992E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,347E-04 6,908E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,347E-04 6,826E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 2,347E-04 6,746E-03 ! response to tumor cell GO:0002347 16 8 1,000 2,347E-04 6,667E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 2,347E-04 6,591E-03 ! positive regulation of ATPase activity GO:0032781 13 8 1,000 2,347E-04 6,516E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 1,000 2,347E-04 6,442E-03 ! gliogenesis GO:0042063 91 41 2,000 2,392E-04 6,494E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 2,953E-04 7,929E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,012E-04 7,998E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 3,012E-04 7,912E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 20 9 1,000 3,012E-04 7,828E-03 ! microtubule bundle formation GO:0001578 22 9 1,000 3,012E-04 7,745E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 3,012E-04 7,665E-03 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 1,000 3,012E-04 7,586E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 3,371E-04 8,403E-03 ! leukocyte migration GO:0050900 75 46 2,000 3,371E-04 8,318E-03 ! negative regulation of cell migration GO:0030336 122 46 2,000 3,371E-04 8,235E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 3,758E-04 9,089E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 3,758E-04 9E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 3,758E-04 8,913E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 3,758E-04 8,827E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 3,758E-04 8,743E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 3,758E-04 8,66E-03 ! motor axon guidance GO:0008045 22 10 1,000 3,758E-04 8,579E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 3,758E-04 8,5E-03 ! induction of an organ GO:0001759 17 10 1,000 3,758E-04 8,422E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 3,758E-04 8,345E-03 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of defense response GO:0031349 88 48 2,000 3,824E-04 8,417E-03 ! regulation of inflammatory response GO:0050727 84 48 2,000 3,824E-04 8,342E-03 ! positive regulation of cell cycle GO:0045787 96 48 2,000 3,824E-04 8,268E-03 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 4,065E-04 8,712E-03 ! regulation of action potential GO:0001508 102 50 2,000 4,316E-04 9,168E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 4,316E-04 9,089E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 4,584E-04 9,571E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 4,584E-04 9,49E-03 ! regulation of intracellular pH GO:0051453 21 11 1,000 4,584E-04 9,41E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 4,584E-04 9,332E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 5,125E-04 0,01034789 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 2,000 5,125E-04 0,01026307 ! regulation of angiogenesis GO:0045765 125 54 2,000 5,415E-04 0,0107556 ! regulation of muscle contraction GO:0006937 94 54 2,000 5,415E-04 0,01066886 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 5,49E-04 0,01072998 ! virus-host interaction GO:0019048 30 12 1,000 5,49E-04 0,01064482 ! regulation of B cell proliferation GO:0030888 22 12 1,000 5,49E-04 0,010561 ! negative regulation of endothelial cell migration GO:0010596 26 12 1,000 5,49E-04 0,01047849 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 5,49E-04 0,01039726 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 5,49E-04 0,01031728 ! developmental induction GO:0031128 22 12 1,000 5,49E-04 0,01023853 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 5,49E-04 0,01016096 ! negative regulation of cell motion GO:0051271 142 55 2,000 5,716E-04 0,01049848 ! regulation of DNA replication GO:0006275 105 56 2,000 6,026E-04 0,01098664 ! nucleotide-excision repair GO:0006289 91 57 2,000 6,348E-04 0,01148672 ! response to X-ray GO:0010165 28 13 1,000 6,476E-04 0,01163297 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 6,476E-04 0,01154806 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 6,476E-04 0,01146438 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 6,476E-04 0,0113819 ! cell-cell junction assembly GO:0007043 32 14 1,000 7,541E-04 0,01315887 ! regulation of cellular pH GO:0030641 27 14 1,000 7,541E-04 0,01306555 ! response to gamma radiation GO:0010332 30 14 1,000 7,541E-04 0,01297353 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 7,541E-04 0,01288281 ! regulation of calcium-mediated signaling GO:0050848 29 14 1,000 7,541E-04 0,01279335 ! regulation of heart contraction GO:0008016 123 61 2,000 7,742E-04 0,01304332 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 7,742E-04 0,01295398 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 8,684E-04 0,0144327 ! G1/S transition checkpoint GO:0031575 37 15 1,000 8,684E-04 0,01433519 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 9,906E-04 0,01624207 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 9,906E-04 0,01613379 ! regulation of ATPase activity GO:0043462 26 16 1,000 9,906E-04 0,01602694 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 9,906E-04 0,0159215 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 9,906E-04 0,01581744 ! negative regulation of cell growth GO:0030308 142 67 2,000 1,017E-03 0,01614046 ! negative regulation of cell size GO:0045792 144 69 2,000 1,108E-03 0,01746494 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 1,121E-03 0,01754816 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of blood coagulation GO:0030195 25 17 1,000 1,121E-03 0,01743639 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,258E-03 0,01945462 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 1,258E-03 0,01933226 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 1,404E-03 0,02143067 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 1,404E-03 0,02129756 ! mitotic chromosome condensation GO:0007076 37 19 1,000 1,404E-03 0,02116609 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 1,404E-03 0,02103624 ! neuromuscular junction development GO:0007528 43 19 1,000 1,404E-03 0,02090797 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 1,404E-03 0,02078125 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 1,557E-03 0,02290743 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,557E-03 0,02277026 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 1,557E-03 0,02263473 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 1,557E-03 0,02250079 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,557E-03 0,02236844 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 1,557E-03 0,02223763 ! cell-cell junction organization GO:0045216 43 20 1,000 1,557E-03 0,02210834 ! negative regulation of T cell activation GO:0050868 41 20 1,000 1,557E-03 0,02198054 ! negative regulation of translation GO:0017148 32 20 1,000 1,557E-03 0,02185422 ! negative regulation of coagulation GO:0050819 30 20 1,000 1,557E-03 0,02172934 ! blood coagulation GO:0007596 151 79 2,000 1,637E-03 0,02272898 GO:0050817|coagulation, ! protein oligomerization GO:0051259 149 79 2,000 1,637E-03 0,02260057 ! activation of protein kinase activity GO:0032147 170 80 2,000 1,698E-03 0,02329989 ! lipid phosphorylation GO:0046834 43 21 1,000 1,717E-03 0,02343521 ! plasma membrane fusion GO:0045026 33 21 1,000 1,717E-03 0,02330501 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 1,717E-03 0,02317625 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 1,885E-03 0,0253055 ! cellular response to starvation GO:0009267 37 22 1,000 1,885E-03 0,02516722 ! cell aging GO:0007569 48 22 1,000 1,885E-03 0,02503044 ! G1 phase GO:0051318 44 22 1,000 1,885E-03 0,02489514 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 1,885E-03 0,02476129 ! peptidyl-serine modification GO:0018209 50 22 1,000 1,885E-03 0,02462888 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,885E-03 0,02449788 ! activation of JUN kinase activity GO:0007257 47 22 1,000 1,885E-03 0,02436826 ! hemostasis GO:0007599 165 85 2,000 2,019E-03 0,02596551 ! negative regulation of growth GO:0045926 168 85 2,000 2,019E-03 0,02582957 ! positive regulation of DNA replication GO:0045740 44 23 1,000 2,061E-03 0,02622198 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 2,061E-03 0,02608612 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 2,061E-03 0,02595165 GO:0010810|regulation of cell-substrate adhesion, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 2,061E-03 0,02581857 ! regulation of protein transport GO:0051223 165 87 2,000 2,158E-03 0,02689803 GO:0070201|regulation of establishment of protein localization, ! regulation of cellular catabolic process GO:0031329 55 24 1,000 2,244E-03 0,02782667 ! sex determination GO:0007530 48 24 1,000 2,244E-03 0,02768613 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 2,244E-03 0,02754701 ! platelet activation GO:0030168 41 24 1,000 2,244E-03 0,02740927 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 2,244E-03 0,02727291 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 2,434E-03 0,02944155 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 2,434E-03 0,02929651 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 2,434E-03 0,0291529 ! negative regulation of DNA replication GO:0008156 45 25 1,000 2,434E-03 0,02901069 ! chromosome condensation GO:0030261 48 25 1,000 2,434E-03 0,02886987 ! interaction with host GO:0051701 66 25 1,000 2,434E-03 0,0287304 ! regulation of cell adhesion GO:0030155 241 92 2,000 2,53E-03 0,02971422 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 2,632E-03 0,03076807 ! negative regulation of cell development GO:0010721 83 26 1,000 2,632E-03 0,03062156 GO:0050768|negative regulation of neurogenesis, ! regulation of blood coagulation GO:0030193 46 26 1,000 2,632E-03 0,03047643 ! positive regulation of nuclear division GO:0051785 41 26 1,000 2,632E-03 0,03033268 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 2,632E-03 0,03019027 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 2,632E-03 0,03004919 ! regulation of membrane potential GO:0042391 179 94 2,000 2,689E-03 0,03055508 ! regulation of defense response GO:0031347 171 95 2,000 2,771E-03 0,03133919 ! mitochondrial membrane organization GO:0007006 60 27 1,000 2,837E-03 0,03194356 ! response to starvation GO:0042594 47 27 1,000 2,837E-03 0,03179703 ! cellular response to nutrient levels GO:0031669 45 27 1,000 2,837E-03 0,03165184 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 2,837E-03 0,03150797 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 2,939E-03 0,03248998 ! regulation of protein localization GO:0032880 188 97 2,000 2,939E-03 0,03234362 ! dendrite development GO:0016358 67 28 1,000 3,05E-03 0,03341148 ! base-excision repair GO:0006284 41 28 1,000 3,05E-03 0,03326232 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 3,05E-03 0,03311449 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 3,05E-03 0,03296797 ! regulation of B cell activation GO:0050864 55 30 1,000 3,496E-03 0,03762864 ! regulation of coagulation GO:0050818 52 30 1,000 3,496E-03 0,0374636 ! cell junction assembly GO:0034329 85 31 1,000 3,73E-03 0,0397966 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 3,73E-03 0,03962357 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 3,73E-03 0,03945204 ! peripheral nervous system development GO:0007422 68 32 1,000 3,972E-03 0,04182114 ! positive regulation of catabolic process GO:0009896 72 32 1,000 3,972E-03 0,04164165 ! regulation of pH GO:0006885 56 33 1,000 4,22E-03 0,04405488 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 4,22E-03 0,04386741 ! response to ionizing radiation GO:0010212 74 33 1,000 4,22E-03 0,04368153 ! glial cell differentiation GO:0010001 67 34 1,000 4,475E-03 0,04612798 ! cell fate specification GO:0001708 56 34 1,000 4,475E-03 0,04593417 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 4,475E-03 0,04574197 ! DNA damage checkpoint GO:0000077 78 35 1,000 4,737E-03 0,04822029 ! negative regulation of secretion GO:0051048 68 35 1,000 4,737E-03 0,04802021 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 4,737E-03 0,04782178 ! calcium-mediated signaling GO:0019722 67 35 1,000 4,737E-03 0,04762498 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 5,006E-03 0,0501244 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 5,006E-03 0,04991981 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 5,282E-03 0,05245805 ! sister chromatid segregation GO:0000819 65 37 1,000 5,282E-03 0,05224567 ! cell junction organization GO:0034330 96 37 1,000 5,282E-03 0,052035 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 5,282E-03 0,05182602 ! regulation of microtubule-based process GO:0032886 86 37 1,000 5,282E-03 0,05161872 ! negative regulation of cell activation GO:0050866 69 37 1,000 5,282E-03 0,05141307 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 5,565E-03 0,05395137 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 5,565E-03 0,05373813 ! DNA integrity checkpoint GO:0031570 82 38 1,000 5,565E-03 0,05352656 ! glycogen metabolic process GO:0005977 63 38 1,000 5,565E-03 0,05331665 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 5,855E-03 0,05587285 ! carbohydrate homeostasis GO:0033500 59 39 1,000 5,855E-03 0,05565545 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 5,855E-03 0,05543973 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 5,855E-03 0,05522568 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 6,151E-03 0,05779882 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 6,455E-03 0,06041522 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 6,764E-03 0,06307399 ! T cell differentiation GO:0030217 93 42 1,000 6,764E-03 0,06283417 ! regulation of T cell differentiation GO:0045580 78 42 1,000 6,764E-03 0,06259616 ! regulation of protein secretion GO:0050708 77 42 1,000 6,764E-03 0,06235995 ! regulation of T cell proliferation GO:0042129 80 43 1,000 7,081E-03 0,06503247 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 7,081E-03 0,0647889 ! energy reserve metabolic process GO:0006112 76 44 1,000 7,404E-03 0,06749262 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 7,404E-03 0,06724172 ! double-strand break repair GO:0006302 85 44 1,000 7,404E-03 0,06699267 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 7,734E-03 0,06971751 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 7,734E-03 0,0694612 ! B cell differentiation GO:0030183 124 45 1,000 7,734E-03 0,06920676 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 8,07E-03 0,07195185 ! cell growth GO:0016049 90 46 1,000 8,07E-03 0,07169021 ! positive regulation of protein transport GO:0051222 80 46 1,000 8,07E-03 0,07143046 ! regulation of JNK cascade GO:0046328 104 47 1,000 8,413E-03 0,07419497 ! mitochondrial transport GO:0006839 94 48 1,000 8,762E-03 0,07699623 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 8,762E-03 0,07672026 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 9,117E-03 0,07954836 ! JNK cascade GO:0007254 106 49 1,000 9,117E-03 0,07926526 ! activation of caspase activity GO:0006919 95 50 1,000 9,479E-03 0,08211941 ! regulation of ossification GO:0030278 123 50 1,000 9,479E-03 0,08182924 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 9,479E-03 0,08154111 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 9,847E-03 0,08441144 ! peptide metabolic process GO:0006518 80 51 1,000 9,847E-03 0,0841163 ! negative regulation of immune system process GO:0002683 101 51 1,000 9,847E-03 0,08382321 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,01022194 0,08670904 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,01022194 0,08640901 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,01022194 0,08611104 ! positive regulation of growth GO:0045927 96 53 1,000 0,0106027 0,08901169 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,0106027 0,08870686 ! synapse organization GO:0050808 102 53 1,000 0,0106027 0,08840411 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,01098967 0,09131894 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 1,000 0,01098967 0,09100938 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,01138281 0,09394662 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,01178207 0,0969145 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,01178207 0,09658929 ! RNA elongation GO:0006354 90 56 1,000 0,01178207 0,09626624 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,01218743 0,09924631 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,01218743 0,09891659 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 1,000 0,01218743 0,09858905 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,01218743 0,09826368 ! heart morphogenesis GO:0003007 105 57 1,000 0,01218743 0,09794044 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,01218743 0,09761933 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,01259884 0,10058486 ! aging GO:0007568 112 58 1,000 0,01259884 0,10025723 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01259884 0,09993171 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,01259884 0,09960831 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01259884 0,09928699 ! lipid modification GO:0030258 112 60 1,000 0,01343967 0,10557268 ! DNA catabolic process GO:0006308 94 60 1,000 0,01343967 0,1052343 ! viral reproductive process GO:0022415 132 62 1,000 0,01430424 0,11164623 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,01430424 0,11129067 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,01430424 0,11093736 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01454521 0,11244918 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01454521 0,11209445 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01454521 0,11174195 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01454521 0,11139166 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01454521 0,11104356 ! neuron fate determination GO:0048664 7 5 0,000 0,01454521 0,11069763 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01454521 0,11035385 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01454521 0,1100122 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01454521 0,10967265 ! polyol transport GO:0015791 12 5 0,000 0,01454521 0,1093352 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01454521 0,10899981 ! response to superoxide GO:0000303 10 5 0,000 0,01454521 0,10866648 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01454521 0,10833518 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01454521 0,1080059 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01454521 0,10767861 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01454521 0,10735329 ! female meiosis GO:0007143 10 5 0,000 0,01454521 0,10702994 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01454521 0,10670853 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01454521 0,10638904 ! hypothalamus development GO:0021854 9 5 0,000 0,01454521 0,10607146 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01454521 0,10575577 ! cobalt ion transport GO:0006824 11 5 0,000 0,01454521 0,10544196 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01454521 0,10513 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01454521 0,10481988 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01454521 0,10451159 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01454521 0,1042051 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01454521 0,10390041 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01454521 0,10359749 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01454521 0,10329634 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01454521 0,10299693 ! transposition GO:0032196 9 5 0,000 0,01454521 0,10269925 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01454521 0,10240328 ! negative chemotaxis GO:0050919 16 5 0,000 0,01454521 0,10210902 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01454521 0,10181645 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01454521 0,10152554 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01454521 0,1012363 ! behavioral response to pain GO:0048266 10 5 0,000 0,01454521 0,10094869 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01454521 0,10066272 ! Notch receptor processing GO:0007220 11 5 0,000 0,01454521 0,10037836 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01454521 0,1000956 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01454521 0,09981444 ! micturition GO:0060073 9 5 0,000 0,01454521 0,09953485 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01454521 0,09925681 ! copulation GO:0007620 9 5 0,000 0,01454521 0,09898033 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01454521 0,09870539 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01454521 0,09843197 ! bioluminescence GO:0008218 9 5 0,000 0,01454521 0,09816005 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01454521 0,09788964 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01454521 0,09762071 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01454521 0,09735326 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01454521 0,09708727 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01454521 0,09682272 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01454521 0,09655962 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01454521 0,09629794 ! grooming behavior GO:0007625 6 5 0,000 0,01454521 0,09603767 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01454521 0,09577881 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01454521 0,09552134 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01454521 0,09526525 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01454521 0,09501053 ! response to protozoan GO:0001562 13 5 0,000 0,01454521 0,09475717 ! lymph vessel development GO:0001945 10 5 0,000 0,01454521 0,09450516 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01454521 0,09425448 ! endochondral ossification GO:0001958 17 5 0,000 0,01454521 0,09400513 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01454521 0,0937571 ! single strand break repair GO:0000012 8 5 0,000 0,01454521 0,09351037 ! parathyroid gland development GO:0060017 14 5 0,000 0,01454521 0,09326493 ! anagen GO:0042640 7 5 0,000 0,01454521 0,09302078 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01454521 0,09277791 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01454521 0,0925363 ! cytokine secretion GO:0050663 15 5 0,000 0,01454521 0,09229595 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01454521 0,09205684 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01454521 0,09181897 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01454521 0,09158232 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01454521 0,09134689 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01454521 0,09111267 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01454521 0,09087964 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01454521 0,09064781 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01454521 0,09041715 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01454521 0,09018766 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01454521 0,08995934 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01454521 0,08973217 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01454521 0,08950615 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01454521 0,08928126 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01454521 0,08905749 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01454521 0,08883485 ! microvillus organization GO:0032528 8 5 0,000 0,01454521 0,08861332 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01454521 0,08839288 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01454521 0,08817355 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01454521 0,0879553 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01454521 0,08773812 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01454521 0,08752202 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01454521 0,08730698 ! polyol catabolic process GO:0046174 9 5 0,000 0,01454521 0,08709299 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01454521 0,08688005 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01454521 0,08666815 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01454521 0,08645727 ! mitochondrial fission GO:0000266 8 5 0,000 0,01454521 0,08624743 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01454521 0,08603859 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01454521 0,08583077 ! mRNA transcription GO:0009299 10 5 0,000 0,01454521 0,08562395 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01454521 0,08541812 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01454521 0,08521328 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01454521 0,08500943 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01454521 0,08480654 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01454521 0,08460462 ! monocyte activation GO:0042117 10 5 0,000 0,01454521 0,08440366 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01454521 0,08420365 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01454521 0,08400459 ! response to food GO:0032094 6 5 0,000 0,01454521 0,08380646 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01454521 0,08360927 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01454521 0,083413 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01454521 0,08321766 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01454521 0,08302322 ! forebrain neuron development GO:0021884 13 5 0,000 0,01454521 0,0828297 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01454521 0,08263707 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01454521 0,08244534 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01454521 0,08225449 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01454521 0,08206453 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01454521 0,08187544 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01454521 0,08168722 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01454521 0,08149986 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01454521 0,08131336 ! lipid glycosylation GO:0030259 7 5 0,000 0,01454521 0,08112772 ! nucleobase transport GO:0015851 6 5 0,000 0,01454521 0,08094291 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01454521 0,08075895 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01454521 0,08057583 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01454521 0,08039353 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01454521 0,08021205 ! basic amino acid transport GO:0015802 12 5 0,000 0,01454521 0,0800314 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01454521 0,07985155 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01454521 0,07967251 ! actin nucleation GO:0045010 11 5 0,000 0,01454521 0,07949427 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01454521 0,07931683 ! depurination GO:0045007 5 5 0,000 0,01454521 0,07914018 ! depyrimidination GO:0045008 10 5 0,000 0,01454521 0,07896431 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01454521 0,07878922 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01454521 0,07861491 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01454521 0,07844137 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01454521 0,07826859 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01454521 0,07809657 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01454521 0,07792531 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01454521 0,07775479 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01454521 0,07758502 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01454521 0,07741599 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01454521 0,07724769 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01454521 0,07708013 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01454521 0,07691329 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01454521 0,07674717 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01454521 0,07658177 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01454521 0,07641707 ! response to arsenic GO:0046685 11 5 0,000 0,01454521 0,07625309 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01454521 0,07608981 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01454521 0,07592722 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01454521 0,07576533 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01454521 0,07560413 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01454521 0,07544361 ! response to mercury ion GO:0046689 8 5 0,000 0,01454521 0,07528377 ! response to cadmium ion GO:0046686 7 5 0,000 0,01454521 0,07512461 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01454521 0,07496612 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01454521 0,07480829 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01454521 0,07465113 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01454521 0,07449463 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01454521 0,07433879 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01454521 0,07418359 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01454521 0,07402904 ! decidualization GO:0046697 11 5 0,000 0,01454521 0,07387513 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01454521 0,07372187 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01454521 0,07356923 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01454521 0,07341723 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01454521 0,07326585 ! embryonic cleavage GO:0040016 6 5 0,000 0,01454521 0,0731151 ! peroxisome fission GO:0016559 5 5 0,000 0,01454521 0,07296497 ! histone demethylation GO:0016577 13 5 0,000 0,01454521 0,07281545 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01454521 0,07266654 ! mitotic recombination GO:0006312 9 5 0,000 0,01454521 0,07251824 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01454521 0,07237055 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01454521 0,07222345 ! metaphase plate congression GO:0051310 7 5 0,000 0,01454521 0,07207696 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01454521 0,07193105 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01454521 0,07178574 ! enteric nervous system development GO:0048484 8 5 0,000 0,01454521 0,07164101 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01454521 0,07149686 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01454521 0,07135329 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01454521 0,0712103 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01454521 0,07106788 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01454521 0,07092603 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01454521 0,07078474 ! B cell homeostasis GO:0001782 13 5 0,000 0,01454521 0,07064402 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01454521 0,07050385 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01454521 0,07036424 ! metaphase GO:0051323 11 5 0,000 0,01454521 0,07022518 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01454521 0,07008667 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01454521 0,0699487 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01454521 0,06981128 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01454521 0,06967439 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01454521 0,06953804 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01454521 0,06940223 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01454521 0,06926694 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01454521 0,06913218 ! response to redox state GO:0051775 6 5 0,000 0,01454521 0,06899794 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01454521 0,06886422 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01454521 0,06873102 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01454521 0,06859834 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01454521 0,06846617 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01454521 0,0683345 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01454521 0,06820334 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01454521 0,06807268 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01454521 0,06794252 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01454521 0,06781286 ! striatum development GO:0021756 14 5 0,000 0,01454521 0,06768369 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01454521 0,06755502 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01454521 0,06742683 ! glial cell migration GO:0008347 10 5 0,000 0,01454521 0,06729913 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01454521 0,06717191 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01454521 0,06704517 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01454521 0,06691891 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01454521 0,06679312 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01454521 0,0666678 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01454521 0,06654296 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01454521 0,06641858 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01454521 0,06629466 ! neuroprotection GO:0043526 8 5 0,000 0,01454521 0,06617121 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01454521 0,06604822 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01454521 0,06592568 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01454521 0,06580359 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01454521 0,06568196 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01454521 0,06556077 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01454521 0,06544004 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01454521 0,06531974 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01454521 0,06519989 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01454521 0,06508048 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01454521 0,0649615 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01454521 0,06484296 ! spindle assembly GO:0051225 6 5 0,000 0,01454521 0,06472484 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01454521 0,06460716 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01454521 0,06448991 ! protein palmitoylation GO:0018345 12 5 0,000 0,01454521 0,06437308 ! drug metabolic process GO:0017144 7 5 0,000 0,01454521 0,06425667 ! stem cell division GO:0017145 11 5 0,000 0,01454521 0,06414069 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01454521 0,06402512 ! organ regeneration GO:0031100 7 5 0,000 0,01454521 0,06390996 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01454521 0,06379522 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01454521 0,0636809 ! regulation of mitosis GO:0007088 112 63 1,000 0,01474535 0,06444165 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,01610347 0,07025137 ! chromosome segregation GO:0007059 127 67 1,000 0,01656765 0,07214754 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,01703751 0,07406165 ! viral reproduction GO:0016032 142 68 1,000 0,01703751 0,0739301 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01703751 0,07379902 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,01703751 0,0736684 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,017429 0,07522802 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,017429 0,07509534 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,017429 0,07496313 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,017429 0,07483139 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,017429 0,0747001 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,017429 0,07456928 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,017429 0,07443891 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,017429 0,074309 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,017429 0,07417954 ! response to oxygen radical GO:0000305 11 6 0,000 0,017429 0,07405054 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,017429 0,07392198 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,017429 0,07379386 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,017429 0,07366619 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,017429 0,07353896 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,017429 0,07341217 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,017429 0,07328581 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,017429 0,07315989 ! forebrain regionalization GO:0021871 9 6 0,000 0,017429 0,07303441 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,017429 0,07290935 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,017429 0,07278472 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,017429 0,07266051 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,017429 0,07253673 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,017429 0,07241336 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,017429 0,07229042 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,017429 0,0721679 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,017429 0,07204578 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,017429 0,07192408 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,017429 0,0718028 ! malate metabolic process GO:0006108 13 6 0,000 0,017429 0,07168192 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,017429 0,07156144 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,017429 0,07144137 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,017429 0,07132171 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,017429 0,07120244 ! protein refolding GO:0042026 15 6 0,000 0,017429 0,07108357 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,017429 0,0709651 ! opsonization GO:0008228 8 6 0,000 0,017429 0,07084702 ! mating behavior GO:0007617 7 6 0,000 0,017429 0,07072933 ! erythrocyte maturation GO:0043249 8 6 0,000 0,017429 0,07061204 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,017429 0,07049513 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,017429 0,07037861 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,017429 0,07026247 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,017429 0,07014672 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,017429 0,07003135 ! response to interferon-gamma GO:0034341 16 6 0,000 0,017429 0,06991635 ! toxin metabolic process GO:0009404 11 6 0,000 0,017429 0,06980173 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,017429 0,06968749 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,017429 0,06957362 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,017429 0,06946013 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,017429 0,069347 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,017429 0,06923424 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,017429 0,06912185 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,017429 0,06900982 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,017429 0,06889815 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,017429 0,06878685 ! thymic T cell selection GO:0045061 16 6 0,000 0,017429 0,0686759 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,017429 0,06856531 ! protein lipoylation GO:0009249 10 6 0,000 0,017429 0,06845508 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,017429 0,0683452 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,017429 0,06823567 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,017429 0,06812649 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,017429 0,06801766 ! glutamate catabolic process GO:0006538 12 6 0,000 0,017429 0,06790918 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,017429 0,06780105 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,017429 0,06769326 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,017429 0,06758581 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,017429 0,0674787 ! hyperosmotic response GO:0006972 10 6 0,000 0,017429 0,06737193 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,017429 0,06726549 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,017429 0,0671594 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,017429 0,06705364 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,017429 0,0669482 ! urea metabolic process GO:0019627 7 6 0,000 0,017429 0,06684311 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,017429 0,06673834 ! neutrophil activation GO:0042119 7 6 0,000 0,017429 0,06663389 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,017429 0,06652978 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,017429 0,06642599 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,017429 0,06632252 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,017429 0,06621938 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,017429 0,06611655 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,017429 0,06601404 ! neuron apoptosis GO:0051402 15 6 0,000 0,017429 0,06591185 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,017429 0,06580998 ! T cell mediated immunity GO:0002456 17 6 0,000 0,017429 0,06570842 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,017429 0,06560718 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,017429 0,06550624 ! carnitine transport GO:0015879 10 6 0,000 0,017429 0,06540562 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,017429 0,0653053 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,017429 0,0652053 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,017429 0,06510559 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,017429 0,0650062 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,017429 0,0649071 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,017429 0,06480831 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,017429 0,06470982 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,017429 0,06461162 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,017429 0,06451372 ! establishment of spindle localization GO:0051293 16 6 0,000 0,017429 0,06441612 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,017429 0,06431882 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,017429 0,06422181 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,017429 0,06412509 ! response to UV-C GO:0010225 14 6 0,000 0,017429 0,06402866 ! astrocyte development GO:0014002 16 6 0,000 0,017429 0,06393252 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,017429 0,06383667 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,017429 0,06374111 ! interaction with symbiont GO:0051702 14 6 0,000 0,017429 0,06364583 ! regulation of dendrite development GO:0050773 16 6 0,000 0,017429 0,06355083 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,017429 0,06345612 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,017429 0,06336169 ! response to copper ion GO:0046688 10 6 0,000 0,017429 0,06326755 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,017429 0,06317368 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,017429 0,06308009 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,017429 0,06298677 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,017429 0,06289373 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,017429 0,06280097 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,017429 0,06270848 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,017429 0,06261626 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,017429 0,06252431 ! hair follicle maturation GO:0048820 8 6 0,000 0,017429 0,06243264 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,017429 0,06234123 ! Schwann cell development GO:0014044 15 6 0,000 0,017429 0,06225009 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,017429 0,06215921 ! response to pheromone GO:0019236 6 6 0,000 0,017429 0,0620686 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,017429 0,06197825 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,017429 0,06188817 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,017429 0,06179834 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,017429 0,06170878 ! subpallium development GO:0021544 15 6 0,000 0,017429 0,06161948 ! neural tube patterning GO:0021532 8 6 0,000 0,017429 0,06153043 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,017429 0,06144164 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,017429 0,06135311 ! maintenance of organ identity GO:0048496 9 6 0,000 0,017429 0,06126483 ! G2 phase GO:0051319 16 6 0,000 0,017429 0,06117681 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,017429 0,06108904 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,017429 0,06100152 ! oxygen homeostasis GO:0032364 10 6 0,000 0,017429 0,06091425 ! establishment of planar polarity GO:0001736 7 6 0,000 0,017429 0,06082723 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,017429 0,06074045 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,017429 0,06065393 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,017429 0,06056765 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,017429 0,06048162 ! receptor internalization GO:0031623 11 6 0,000 0,017429 0,06039583 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,017429 0,06031028 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,017429 0,06022498 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,017429 0,06013991 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,017429 0,06005509 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,017429 0,0599705 ! protein deubiquitination GO:0016579 16 6 0,000 0,017429 0,05988616 ! protein destabilization GO:0031648 9 6 0,000 0,017429 0,05980205 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,017429 0,05971817 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,017429 0,05963454 ! regulation of viral transcription GO:0046782 11 6 0,000 0,017429 0,05955113 ! progesterone metabolic process GO:0042448 12 6 0,000 0,017429 0,05946796 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,017429 0,05938502 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,017429 0,05930231 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,017429 0,05921983 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,017429 0,05913758 ! determination of adult lifespan GO:0008340 17 6 0,000 0,017429 0,05905556 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,017429 0,05897376 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,017429 0,0588922 ! neural plate development GO:0001840 9 6 0,000 0,017429 0,05881085 ! catecholamine transport GO:0051937 9 6 0,000 0,017429 0,05872974 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,017429 0,05864884 ! sensory cilium assembly GO:0035058 10 6 0,000 0,017429 0,05856817 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,017429 0,05848772 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,017429 0,05840749 ! maternal placenta development GO:0001893 12 6 0,000 0,017429 0,05832748 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,017429 0,05824769 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,017429 0,05816811 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,017429 0,05808876 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,017429 0,05800962 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,017429 0,05793069 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,017429 0,05785198 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,017429 0,05777348 GO:0055081|anion homeostasis, ! lung development GO:0030324 165 69 1,000 0,01751302 0,05797331 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,01751302 0,05789487 ! single fertilization GO:0007338 83 69 1,000 0,01751302 0,05781663 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,01848081 0,06092931 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,01848081 0,06084719 ! respiratory tube development GO:0030323 171 72 1,000 0,01897302 0,06238371 ! B cell activation GO:0042113 179 72 1,000 0,01897302 0,06229986 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,01897302 0,06221623 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,01897302 0,06213283 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,01897302 0,06204966 ! regulation of caspase activity GO:0043281 136 74 1,000 0,0199739 0,06523563 ! respiratory system development GO:0060541 175 74 1,000 0,0199739 0,06514853 ! tRNA transcription GO:0009304 17 7 0,000 0,02030444 0,06613834 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02030444 0,06605028 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02030444 0,06596244 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02030444 0,06587484 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02030444 0,06578748 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02030444 0,06570034 ! sleep GO:0030431 16 7 0,000 0,02030444 0,06561344 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02030444 0,06552676 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02030444 0,06544031 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02030444 0,06535409 ! prostate gland development GO:0030850 14 7 0,000 0,02030444 0,0652681 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02030444 0,06518234 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02030444 0,0650968 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02030444 0,06501148 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02030444 0,06492638 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02030444 0,06484151 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02030444 0,06475686 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02030444 0,06467244 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02030444 0,06458823 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02030444 0,06450424 ! glycolipid transport GO:0046836 11 7 0,000 0,02030444 0,06442046 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02030444 0,06433691 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02030444 0,06425357 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,02030444 0,06417045 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02030444 0,06408754 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02030444 0,06400485 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02030444 0,06392237 ! mRNA stabilization GO:0048255 18 7 0,000 0,02030444 0,0638401 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02030444 0,06375804 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02030444 0,0636762 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02030444 0,06359456 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02030444 0,06351313 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02030444 0,06343192 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02030444 0,0633509 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02030444 0,0632701 ! lipoprotein transport GO:0042953 14 7 0,000 0,02030444 0,0631895 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02030444 0,06310911 ! rhythmic behavior GO:0007622 17 7 0,000 0,02030444 0,06302892 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02030444 0,06294893 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02030444 0,06286915 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02030444 0,06278957 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02030444 0,06271019 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02030444 0,06263101 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02030444 0,06255203 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02030444 0,06247325 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02030444 0,06239466 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02030444 0,06231628 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02030444 0,06223809 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02030444 0,0621601 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02030444 0,0620823 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02030444 0,0620047 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02030444 0,06192729 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02030444 0,06185007 ! spinal cord patterning GO:0021511 14 7 0,000 0,02030444 0,06177305 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02030444 0,06169622 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02030444 0,06161958 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02030444 0,06154312 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02030444 0,06146686 ! adrenal gland development GO:0030325 17 7 0,000 0,02030444 0,06139079 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02030444 0,0613149 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02030444 0,06123921 ! ovulation GO:0030728 10 7 0,000 0,02030444 0,0611637 ! adenohypophysis development GO:0021984 11 7 0,000 0,02030444 0,06108837 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02030444 0,06101323 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02030444 0,06093828 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02030444 0,06086351 ! microtubule nucleation GO:0007020 21 7 0,000 0,02030444 0,06078892 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02030444 0,06071451 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02030444 0,06064029 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02030444 0,06056625 ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02030444 0,06049239 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02030444 0,06041871 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02030444 0,0603452 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02030444 0,06027188 ! galactose metabolic process GO:0006012 13 7 0,000 0,02030444 0,06019874 ! vesicle fusion GO:0006906 20 7 0,000 0,02030444 0,06012577 ! response to dietary excess GO:0002021 8 7 0,000 0,02030444 0,06005298 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02030444 0,05998036 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02030444 0,05990792 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02030444 0,05983565 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02030444 0,05976356 ! organ growth GO:0035265 15 7 0,000 0,02030444 0,05969165 ! nucleoside transport GO:0015858 11 7 0,000 0,02030444 0,0596199 ! nucleoside salvage GO:0043174 11 7 0,000 0,02030444 0,05954833 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02030444 0,05947693 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02030444 0,0594057 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02030444 0,05933464 ! parturition GO:0007567 16 7 0,000 0,02030444 0,05926375 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02030444 0,05919303 ! rRNA modification GO:0000154 14 7 0,000 0,02030444 0,05912248 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02030444 0,05905209 ! spindle checkpoint GO:0031577 16 7 0,000 0,02030444 0,05898188 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02030444 0,05891183 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02030444 0,05884194 ! monocyte differentiation GO:0030224 16 7 0,000 0,02030444 0,05877223 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02030444 0,05870267 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02030444 0,05863328 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02030444 0,05856406 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02030444 0,058495 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02030444 0,0584261 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02030444 0,05835736 ! eating behavior GO:0042755 8 7 0,000 0,02030444 0,05828879 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02030444 0,05822037 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02030444 0,05815212 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02030444 0,05808403 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02030444 0,05801609 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02030444 0,05794832 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02030444 0,0578807 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02030444 0,05781324 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02030444 0,05774593 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02030444 0,05767879 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02030444 0,0576118 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02030444 0,05754496 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02030444 0,05747828 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02030444 0,05741176 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02030444 0,05734538 ! histone ubiquitination GO:0016574 9 7 0,000 0,02030444 0,05727917 ! regulation of meiosis GO:0040020 12 7 0,000 0,02030444 0,0572131 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02030444 0,05714719 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02030444 0,05708142 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02030444 0,05701581 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02030444 0,05695035 ! transcription termination GO:0006353 14 7 0,000 0,02030444 0,05688504 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02030444 0,05681988 ! anaphase GO:0051322 18 7 0,000 0,02030444 0,05675487 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02030444 0,05669001 ! axonal fasciculation GO:0007413 19 7 0,000 0,02030444 0,05662529 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02030444 0,05656073 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02030444 0,05649631 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02030444 0,05643203 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02030444 0,05636791 ! diuresis GO:0030146 12 7 0,000 0,02030444 0,05630393 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02030444 0,05624009 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02030444 0,0561764 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02030444 0,05611285 ! antibiotic transport GO:0042891 9 7 0,000 0,02030444 0,05604944 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02030444 0,05598618 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02030444 0,05592306 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02030444 0,05586009 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02030444 0,05579725 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02030444 0,05573456 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02030444 0,05567201 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02030444 0,05560959 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02030444 0,05554732 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02030444 0,05548519 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02030444 0,05542319 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02030444 0,05536134 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02030444 0,05529962 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02030444 0,05523804 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02030444 0,05517659 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02030444 0,05511529 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02030444 0,05505412 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02030444 0,05499308 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02030444 0,05493218 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02030444 0,05487141 ! muscle adaptation GO:0043500 13 7 0,000 0,02030444 0,05481078 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02030444 0,05475028 ! retina homeostasis GO:0001895 12 7 0,000 0,02030444 0,05468992 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02030444 0,05462969 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02030444 0,05456959 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02030444 0,05450962 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02030444 0,05444979 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,0204825 0,05486705 ! axon guidance GO:0007411 162 75 1,000 0,0204825 0,05480696 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,02099649 0,05612082 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,02151583 0,0574461 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,02151583 0,05738339 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,02151583 0,05732081 ! regulation of catabolic process GO:0009894 173 77 1,000 0,02151583 0,05725837 ! fertilization GO:0009566 99 78 1,000 0,0220405 0,05859079 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,0220405 0,0585271 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,02257045 0,05986928 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,02310565 0,06122245 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02317155 0,06133055 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02317155 0,06126417 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02317155 0,06119794 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02317155 0,06113185 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02317155 0,06106591 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02317155 0,0610001 ! male meiosis GO:0007140 9 8 0,000 0,02317155 0,06093444 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02317155 0,06086892 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02317155 0,06080354 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02317155 0,0607383 ! meiotic prophase I GO:0007128 14 8 0,000 0,02317155 0,0606732 ! response to zinc ion GO:0010043 12 8 0,000 0,02317155 0,06060824 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,02317155 0,06054342 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02317155 0,06047874 ! oligopeptide transport GO:0006857 16 8 0,000 0,02317155 0,06041419 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02317155 0,06034978 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02317155 0,06028551 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02317155 0,06022138 ! signal peptide processing GO:0006465 12 8 0,000 0,02317155 0,06015738 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02317155 0,06009352 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02317155 0,0600298 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02317155 0,0599662 ! succinate metabolic process GO:0006105 17 8 0,000 0,02317155 0,05990275 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02317155 0,05983943 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02317155 0,05977624 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02317155 0,05971318 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02317155 0,05965026 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02317155 0,05958747 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02317155 0,05952481 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02317155 0,05946229 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02317155 0,05939989 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02317155 0,05933763 ! reflex GO:0060004 17 8 0,000 0,02317155 0,05927549 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02317155 0,05921349 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02317155 0,05915162 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02317155 0,05908987 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02317155 0,05902826 ! pigment granule organization GO:0048753 17 8 0,000 0,02317155 0,05896677 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02317155 0,05890541 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02317155 0,05884418 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02317155 0,05878307 ! histidine catabolic process GO:0006548 10 8 0,000 0,02317155 0,05872209 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02317155 0,05866124 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02317155 0,05860051 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02317155 0,05853991 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02317155 0,05847944 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02317155 0,05841909 ! melanin metabolic process GO:0006582 17 8 0,000 0,02317155 0,05835886 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02317155 0,05829876 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02317155 0,05823878 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02317155 0,05817893 ! macrophage activation GO:0042116 13 8 0,000 0,02317155 0,0581192 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02317155 0,05805959 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02317155 0,0580001 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02317155 0,05794073 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02317155 0,05788149 ! purine salvage GO:0043101 12 8 0,000 0,02317155 0,05782237 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02317155 0,05776336 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02317155 0,05770448 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02317155 0,05764572 ! osteoblast development GO:0002076 17 8 0,000 0,02317155 0,05758708 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02317155 0,05752855 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02317155 0,05747015 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02317155 0,05741186 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02317155 0,0573537 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02317155 0,05729565 ! response to UV-B GO:0010224 17 8 0,000 0,02317155 0,05723771 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02317155 0,0571799 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02317155 0,0571222 ! intermediate filament organization GO:0045109 12 8 0,000 0,02317155 0,05706461 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02317155 0,05700715 ! cellular extravasation GO:0045123 13 8 0,000 0,02317155 0,0569498 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02317155 0,05689256 ! response to antibiotic GO:0046677 11 8 0,000 0,02317155 0,05683544 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02317155 0,05677843 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02317155 0,05672154 ! DNA topological change GO:0006265 12 8 0,000 0,02317155 0,05666476 ! response to tropane GO:0014073 15 8 0,000 0,02317155 0,0566081 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,02317155 0,05655155 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02317155 0,05649511 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02317155 0,05643878 ! mast cell activation GO:0045576 14 8 0,000 0,02317155 0,05638257 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02317155 0,05632647 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02317155 0,05627047 ! gas homeostasis GO:0033483 14 8 0,000 0,02317155 0,0562146 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02317155 0,05615883 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02317155 0,05610317 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02317155 0,05604762 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02317155 0,05599218 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02317155 0,05593686 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02317155 0,05588164 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02317155 0,05582653 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02317155 0,05577152 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02317155 0,05571663 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02317155 0,05566185 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02317155 0,05560717 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02317155 0,0555526 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02317155 0,05549813 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02317155 0,05544378 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02317155 0,05538953 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02317155 0,05533538 ! hormone catabolic process GO:0042447 17 8 0,000 0,02317155 0,05528135 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02317155 0,05522741 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02317155 0,05517358 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02317155 0,05511986 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02317155 0,05506624 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02317155 0,05501273 ! adult feeding behavior GO:0008343 10 8 0,000 0,02317155 0,05495932 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02317155 0,05490601 ! ATP catabolic process GO:0006200 11 8 0,000 0,02317155 0,05485281 ! blastocyst growth GO:0001832 19 8 0,000 0,02317155 0,05479971 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02317155 0,05474671 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02317155 0,05469381 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02317155 0,05464102 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02317155 0,05458833 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02317155 0,05453574 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02317155 0,05448325 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02317155 0,05443086 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02317155 0,05437858 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02317155 0,05432639 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02317155 0,0542743 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02317155 0,05422232 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02317155 0,05417043 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02317155 0,05411864 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02317155 0,05406695 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02317155 0,05401536 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02317155 0,05396387 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02317155 0,05391247 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02317155 0,05386118 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02317155 0,05380998 ! response to hypoxia GO:0001666 178 81 1,000 0,02364606 0,05485976 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,02364606 0,05480771 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,02419166 0,05601917 ! protein import into nucleus GO:0006606 174 82 1,000 0,02419166 0,05596612 ! response to drug GO:0042493 149 83 1,000 0,0247424 0,05718608 ! response to oxygen levels GO:0070482 183 83 1,000 0,0247424 0,05713203 ! nuclear import GO:0051170 177 83 1,000 0,0247424 0,05707808 ! T cell activation GO:0042110 189 84 1,000 0,02529826 0,05830533 ! regulation of ligase activity GO:0051340 147 84 1,000 0,02529826 0,05825038 ! axon extension GO:0048675 16 9 0,000 0,02603035 0,0598796 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02603035 0,05982327 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02603035 0,05976704 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02603035 0,05971092 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02603035 0,05965491 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02603035 0,059599 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02603035 0,0595432 ! reproductive behavior GO:0019098 22 9 0,000 0,02603035 0,0594875 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02603035 0,0594319 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02603035 0,05937641 ! UTP metabolic process GO:0046051 10 9 0,000 0,02603035 0,05932102 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02603035 0,05926574 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02603035 0,05921055 ! artery development GO:0060840 25 9 0,000 0,02603035 0,05915547 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02603035 0,0591005 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02603035 0,05904562 ! equilibrioception GO:0050957 20 9 0,000 0,02603035 0,05899085 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02603035 0,05893618 ! chemosensory behavior GO:0007635 21 9 0,000 0,02603035 0,05888161 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02603035 0,05882714 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02603035 0,05877277 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02603035 0,0587185 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02603035 0,05866433 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02603035 0,05861026 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02603035 0,05855629 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02603035 0,05850242 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02603035 0,05844865 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02603035 0,05839498 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02603035 0,05834141 ! protein targeting to ER GO:0045047 25 9 0,000 0,02603035 0,05828793 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02603035 0,05823456 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02603035 0,05818128 ! T cell selection GO:0045058 27 9 0,000 0,02603035 0,05812809 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02603035 0,05807501 ! glycine catabolic process GO:0006546 15 9 0,000 0,02603035 0,05802202 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02603035 0,05796913 ! endosome organization GO:0007032 20 9 0,000 0,02603035 0,05791633 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02603035 0,05786364 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02603035 0,05781103 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02603035 0,05775852 ! mannose metabolic process GO:0006013 13 9 0,000 0,02603035 0,05770611 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02603035 0,05765379 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02603035 0,05760157 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02603035 0,05754944 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02603035 0,05749741 ! receptor clustering GO:0043113 20 9 0,000 0,02603035 0,05744547 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02603035 0,05739362 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02603035 0,05734187 ! retinol metabolic process GO:0042572 20 9 0,000 0,02603035 0,05729021 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02603035 0,05723865 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02603035 0,05718717 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02603035 0,05713579 ! macrophage differentiation GO:0030225 15 9 0,000 0,02603035 0,0570845 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02603035 0,0570333 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02603035 0,0569822 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02603035 0,05693119 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02603035 0,05688026 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02603035 0,05682943 ! response to amine stimulus GO:0014075 13 9 0,000 0,02603035 0,05677869 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02603035 0,05672804 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02603035 0,05667748 ! erythrocyte development GO:0048821 17 9 0,000 0,02603035 0,05662701 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02603035 0,05657663 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02603035 0,05652634 ! renal water homeostasis GO:0003091 15 9 0,000 0,02603035 0,05647614 ! postreplication repair GO:0006301 25 9 0,000 0,02603035 0,05642603 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02603035 0,05637601 ! icosanoid secretion GO:0032309 15 9 0,000 0,02603035 0,05632607 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02603035 0,05627623 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02603035 0,05622647 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02603035 0,0561768 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02603035 0,05612722 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02603035 0,05607772 ! sterol catabolic process GO:0016127 14 9 0,000 0,02603035 0,05602831 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02603035 0,05597899 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02603035 0,05592976 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02603035 0,05588061 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02603035 0,05583155 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02603035 0,05578257 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02603035 0,05573369 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02603035 0,05568488 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02603035 0,05563616 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02603035 0,05558753 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02603035 0,05553898 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02603035 0,05549052 ! purine base metabolic process GO:0006144 25 9 0,000 0,02603035 0,05544214 ! pigment granule transport GO:0051904 17 9 0,000 0,02603035 0,05539385 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02603035 0,05534564 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02603035 0,05529751 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02603035 0,05524947 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02603035 0,05520151 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02603035 0,05515363 ! mitochondrion localization GO:0051646 18 9 0,000 0,02603035 0,05510584 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,02642518 0,05589325 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 0,02699617 0,05705159 ! tube morphogenesis GO:0035239 194 89 1,000 0,02815305 0,05944504 ! protein localization in nucleus GO:0034504 192 89 1,000 0,02815305 0,0593937 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,02873888 0,06057729 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02888086 0,06082408 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02888086 0,06077169 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02888086 0,06071939 ! associative learning GO:0008306 21 10 0,000 0,02888086 0,06066718 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02888086 0,06061506 ! phosphate transport GO:0006817 24 10 0,000 0,02888086 0,06056303 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02888086 0,06051109 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02888086 0,06045924 ! CTP metabolic process GO:0046036 11 10 0,000 0,02888086 0,06040747 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02888086 0,0603558 ! GTP metabolic process GO:0046039 11 10 0,000 0,02888086 0,06030421 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02888086 0,06025271 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02888086 0,0602013 ! social behavior GO:0035176 29 10 0,000 0,02888086 0,06014998 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02888086 0,06009875 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02888086 0,0600476 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02888086 0,05999654 ! androgen metabolic process GO:0008209 17 10 0,000 0,02888086 0,05994556 ! phospholipid efflux GO:0033700 19 10 0,000 0,02888086 0,05989468 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02888086 0,05984388 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02888086 0,05979316 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02888086 0,05974253 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02888086 0,05969199 ! lung alveolus development GO:0048286 26 10 0,000 0,02888086 0,05964153 ! pathogenesis GO:0009405 17 10 0,000 0,02888086 0,05959116 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02888086 0,05954087 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02888086 0,05949067 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02888086 0,05944055 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02888086 0,05939051 ! endoderm development GO:0007492 18 10 0,000 0,02888086 0,05934056 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02888086 0,0592907 ! arginine catabolic process GO:0006527 17 10 0,000 0,02888086 0,05924091 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02888086 0,05919122 ! proline metabolic process GO:0006560 13 10 0,000 0,02888086 0,0591416 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02888086 0,05909207 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02888086 0,05904262 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02888086 0,05899325 ! V(D)J recombination GO:0033151 34 10 0,000 0,02888086 0,05894397 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02888086 0,05889477 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02888086 0,05884565 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02888086 0,05879661 ! B cell proliferation GO:0042100 19 10 0,000 0,02888086 0,05874765 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02888086 0,05869878 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02888086 0,05864998 ! multicellular organism growth GO:0035264 19 10 0,000 0,02888086 0,05860127 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02888086 0,05855264 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02888086 0,05850409 ! ruffle organization GO:0031529 17 10 0,000 0,02888086 0,05845562 ! epithelial cell development GO:0002064 21 10 0,000 0,02888086 0,05840723 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02888086 0,05835892 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02888086 0,05831069 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02888086 0,05826253 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02888086 0,05821446 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02888086 0,05816647 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02888086 0,05811856 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,02888086 0,05807072 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02888086 0,05802297 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02888086 0,05797529 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02888086 0,05792769 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02888086 0,05788017 ! segment specification GO:0007379 15 10 0,000 0,02888086 0,05783273 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02888086 0,05778536 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02888086 0,05773808 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02888086 0,05769087 ! response to dsRNA GO:0043331 23 10 0,000 0,02888086 0,05764373 ! DNA ligation GO:0006266 18 10 0,000 0,02888086 0,05759668 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02888086 0,0575497 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02888086 0,05750279 ! melanosome localization GO:0032400 16 10 0,000 0,02888086 0,05745597 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02888086 0,05740922 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02888086 0,05736254 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02888086 0,05731595 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02888086 0,05726942 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02888086 0,05722298 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02888086 0,0571766 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02888086 0,05713031 ! protein sumoylation GO:0016925 17 10 0,000 0,02888086 0,05708408 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02888086 0,05703794 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02888086 0,05699186 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02888086 0,05694587 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02888086 0,05689994 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02888086 0,05685409 ! salivary gland development GO:0007431 28 10 0,000 0,02888086 0,05680832 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02888086 0,05676261 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02888086 0,05671698 ! midbrain development GO:0030901 14 10 0,000 0,02888086 0,05667143 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02888086 0,05662595 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02888086 0,05658054 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02888086 0,0565352 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02888086 0,05648994 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02888086 0,05644474 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02888086 0,05639962 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02888086 0,05635458 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02888086 0,0563096 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02888086 0,0562647 ! detection of calcium ion GO:0005513 24 10 0,000 0,02888086 0,05621986 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02888086 0,0561751 ! blastocyst formation GO:0001825 18 10 0,000 0,02888086 0,05613041 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02888086 0,05608579 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02888086 0,05604125 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02888086 0,05599677 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02888086 0,05595236 ! response to nicotine GO:0035094 20 10 0,000 0,02888086 0,05590803 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02888086 0,05586376 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02888086 0,05581956 ! ossification GO:0001503 205 91 1,000 0,02932958 0,05664203 ! gland development GO:0048732 220 91 1,000 0,02932958 0,05659729 ! bone development GO:0060348 206 92 1,000 0,02992513 0,05770094 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,03052549 0,05881213 GO:0010498|proteasomal protein catabolic process, ! negative regulation of muscle development GO:0048635 27 11 0,000 0,0317231 0,06107135 ! respiratory burst GO:0045730 17 11 0,000 0,0317231 0,06102326 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0317231 0,06097525 ! neuron fate specification GO:0048665 18 11 0,000 0,0317231 0,06092731 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0317231 0,06087945 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0317231 0,06083166 ! thyroid gland development GO:0030878 26 11 0,000 0,0317231 0,06078395 ! synapsis GO:0007129 14 11 0,000 0,0317231 0,06073631 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0317231 0,06068875 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0317231 0,06064127 ! response to pain GO:0048265 27 11 0,000 0,0317231 0,06059385 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0317231 0,06054651 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0317231 0,06049925 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0317231 0,06045206 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,0317231 0,06040494 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,0317231 0,0603579 ! bone resorption GO:0045453 16 11 0,000 0,0317231 0,06031092 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0317231 0,06026403 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,0317231 0,0602172 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0317231 0,06017045 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0317231 0,06012377 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0317231 0,06007716 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0317231 0,06003063 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0317231 0,05998416 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0317231 0,05993777 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0317231 0,05989145 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0317231 0,0598452 ! UV protection GO:0009650 20 11 0,000 0,0317231 0,05979903 ! adult heart development GO:0007512 16 11 0,000 0,0317231 0,05975292 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0317231 0,05970689 ! macroautophagy GO:0016236 19 11 0,000 0,0317231 0,05966092 ! temperature homeostasis GO:0001659 18 11 0,000 0,0317231 0,05961503 ! behavioral fear response GO:0001662 27 11 0,000 0,0317231 0,05956921 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0317231 0,05952345 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0317231 0,05947777 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0317231 0,05943216 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0317231 0,05938662 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0317231 0,05934115 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0317231 0,05929574 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0317231 0,05925041 ! regulation of organ growth GO:0046620 14 11 0,000 0,0317231 0,05920515 ! pigment granule localization GO:0051875 20 11 0,000 0,0317231 0,05915995 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0317231 0,05911483 ! vasoconstriction GO:0042310 20 11 0,000 0,0317231 0,05906977 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0317231 0,05902478 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0317231 0,05897986 ! embryonic axis specification GO:0000578 19 11 0,000 0,0317231 0,05893501 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0317231 0,05889023 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0317231 0,05884551 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0317231 0,05880086 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0317231 0,05875628 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0317231 0,05871177 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0317231 0,05866733 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0317231 0,05862295 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0317231 0,05857864 ! prophase GO:0051324 17 11 0,000 0,0317231 0,05853439 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0317231 0,05849022 ! nucleosome positioning GO:0016584 15 11 0,000 0,0317231 0,05844611 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0317231 0,05840206 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0317231 0,05835809 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0317231 0,05831417 ! apical protein localization GO:0045176 18 11 0,000 0,0317231 0,05827033 ! acid secretion GO:0046717 20 11 0,000 0,0317231 0,05822655 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0317231 0,05818284 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0317231 0,05813919 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,0317231 0,05809561 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0317231 0,05805209 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0317231 0,05800864 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0317231 0,05796525 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,0317231 0,05792193 ! cholesterol efflux GO:0033344 21 11 0,000 0,0317231 0,05787867 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0317231 0,05783548 ! oocyte development GO:0048599 20 11 0,000 0,0317231 0,05779235 ! germ cell migration GO:0008354 26 11 0,000 0,0317231 0,05774928 ! embryonic gut development GO:0048566 19 11 0,000 0,0317231 0,05770628 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0317231 0,05766335 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0317231 0,05762047 ! activation of innate immune response GO:0002218 16 11 0,000 0,0317231 0,05757767 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0317231 0,05753492 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0317231 0,05749224 ! lysogeny GO:0030069 22 11 0,000 0,0317231 0,05744962 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0317231 0,05740706 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,0317231 0,05736457 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0317231 0,05732214 ! nucleus localization GO:0051647 22 11 0,000 0,0317231 0,05727978 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,03174052 0,0572689 ! regulation of T cell activation GO:0050863 175 96 1,000 0,03235512 0,05833473 ! transcription initiation GO:0006352 171 97 1,000 0,0329744 0,05940743 ! leukocyte differentiation GO:0002521 232 98 1,000 0,03359834 0,06048691 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03455711 0,06216717 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03455711 0,06212143 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03455711 0,06207575 ! mating GO:0007618 17 12 0,000 0,03455711 0,06203014 ! protein complex disassembly GO:0043241 28 12 0,000 0,03455711 0,06198459 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03455711 0,06193912 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,03455711 0,06189371 ! hippocampus development GO:0021766 29 12 0,000 0,03455711 0,06184837 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,03455711 0,06180309 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03455711 0,06175788 ! T cell proliferation GO:0042098 32 12 0,000 0,03455711 0,06171273 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03455711 0,06166765 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03455711 0,06162264 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03455711 0,06157769 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03455711 0,06153281 ! drug transport GO:0015893 16 12 0,000 0,03455711 0,061488 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03455711 0,06144324 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03455711 0,06139856 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03455711 0,06135394 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03455711 0,06130938 ! focal adhesion formation GO:0048041 37 12 0,000 0,03455711 0,06126489 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03455711 0,06122046 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03455711 0,0611761 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03455711 0,0611318 ! lipid digestion GO:0044241 21 12 0,000 0,03455711 0,06108757 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03455711 0,0610434 ! entry into host cell GO:0030260 34 12 0,000 0,03455711 0,06099929 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03455711 0,06095525 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03455711 0,06091127 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03455711 0,06086735 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03455711 0,0608235 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03455711 0,06077971 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03455711 0,06073598 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03455711 0,06069232 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03455711 0,06064872 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03455711 0,06060518 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03455711 0,06056171 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03455711 0,06051829 ! cranial nerve development GO:0021545 23 12 0,000 0,03455711 0,06047494 ! fucose catabolic process GO:0019317 25 12 0,000 0,03455711 0,06043165 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03455711 0,06038843 ! histone acetylation GO:0016573 27 12 0,000 0,03455711 0,06034526 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03455711 0,06030216 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03455711 0,06025911 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,03455711 0,06021613 ! zymogen activation GO:0031638 18 12 0,000 0,03455711 0,06017321 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03455711 0,06013035 ! T cell homeostasis GO:0043029 28 12 0,000 0,03455711 0,06008756 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03455711 0,06004482 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03455711 0,06000215 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,03455711 0,05995953 ! oocyte differentiation GO:0009994 21 12 0,000 0,03455711 0,05991698 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03455711 0,05987448 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03455711 0,05983205 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03455711 0,05978967 ! defense response to fungus GO:0050832 15 12 0,000 0,03455711 0,05974736 ! embryonic placenta development GO:0001892 21 12 0,000 0,03455711 0,0597051 ! lamellipodium assembly GO:0030032 24 12 0,000 0,03455711 0,05966291 ! response to cold GO:0009409 17 12 0,000 0,03455711 0,05962078 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03455711 0,0595787 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03455711 0,05953668 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,03486003 0,06001625 GO:0060538|skeletal muscle organ development, ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,0373829 0,06431439 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0373829 0,06426913 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,0373829 0,06422393 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0373829 0,0641788 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0373829 0,06413373 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,0373829 0,06408872 ! peroxisomal transport GO:0043574 28 13 0,000 0,0373829 0,06404378 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,0373829 0,0639989 ! cartilage condensation GO:0001502 22 13 0,000 0,0373829 0,06395408 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,0373829 0,06390933 ! organelle fusion GO:0048284 36 13 0,000 0,0373829 0,06386464 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,0373829 0,06382001 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,0373829 0,06377544 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,0373829 0,06373093 ! endocrine pancreas development GO:0031018 25 13 0,000 0,0373829 0,06368649 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,0373829 0,06364211 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,0373829 0,06359779 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,0373829 0,06355353 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,0373829 0,06350934 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,0373829 0,0634652 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0373829 0,06342113 ! methionine metabolic process GO:0006555 31 13 0,000 0,0373829 0,06337712 ! plasma membrane organization GO:0007009 27 13 0,000 0,0373829 0,06333317 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,0373829 0,06328928 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,0373829 0,06324545 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,0373829 0,06320168 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,0373829 0,06315797 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,0373829 0,06311433 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,0373829 0,06307074 ! exocrine system development GO:0035272 34 13 0,000 0,0373829 0,06302721 ! asymmetric protein localization GO:0008105 24 13 0,000 0,0373829 0,06298374 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,0373829 0,06294034 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,0373829 0,06289699 ! L-glutamate transport GO:0015813 30 13 0,000 0,0373829 0,0628537 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,0373829 0,06281047 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,0373829 0,06276731 ! protein homotetramerization GO:0051289 24 13 0,000 0,0373829 0,0627242 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,0373829 0,06268115 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,0373829 0,06263815 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,0373829 0,06259522 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,0373829 0,06255235 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,0373829 0,06250953 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0373829 0,06246678 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,0373829 0,06242408 ! histone methylation GO:0016571 29 13 0,000 0,0373829 0,06238144 ! chromatin silencing GO:0006342 29 13 0,000 0,0373829 0,06233886 ! gland morphogenesis GO:0022612 31 13 0,000 0,0373829 0,06229634 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,0373829 0,06225387 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0373829 0,06221146 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,0373829 0,06216911 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,0373829 0,06212682 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,0373829 0,06208459 ! spleen development GO:0048536 24 13 0,000 0,0373829 0,06204241 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,0373829 0,06200029 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,0373829 0,06195823 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,0373829 0,06191622 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,0373829 0,06187427 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,0373829 0,06183238 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0373829 0,06179055 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,0373829 0,06174877 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,0373829 0,06170705 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,0373829 0,06166538 ! insulin secretion GO:0030073 24 13 0,000 0,0373829 0,06162377 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,0373829 0,06158222 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,0373829 0,06154072 ! acrosome reaction GO:0007340 19 13 0,000 0,0373829 0,06149928 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,0373829 0,06145789 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,0373829 0,06141656 ! rRNA transcription GO:0009303 28 14 0,000 0,0402005 0,06600123 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,0402005 0,0659569 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,0402005 0,06591264 ! water transport GO:0006833 21 14 0,000 0,0402005 0,06586843 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,0402005 0,06582428 ! non-recombinational repair GO:0000726 29 14 0,000 0,0402005 0,06578019 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,0402005 0,06573616 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,0402005 0,06569219 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,0402005 0,06564828 ! RNA polyadenylation GO:0043631 32 14 0,000 0,0402005 0,06560443 ! lipid localization GO:0010876 32 14 0,000 0,0402005 0,06556063 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,0402005 0,0655169 ! regulated secretory pathway GO:0045055 24 14 0,000 0,0402005 0,06547322 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,0402005 0,0654296 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,0402005 0,06538604 ! arginine metabolic process GO:0006525 21 14 0,000 0,0402005 0,06534253 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,0402005 0,06529909 ! regulation of heart rate GO:0002027 25 14 0,000 0,0402005 0,0652557 ! fear response GO:0042596 34 14 0,000 0,0402005 0,06521237 ! organic alcohol transport GO:0015850 29 14 0,000 0,0402005 0,0651691 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,0402005 0,06512588 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,0402005 0,06508272 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0402005 0,06503962 ! neutral amino acid transport GO:0015804 28 14 0,000 0,0402005 0,06499658 ! bone mineralization GO:0030282 18 14 0,000 0,0402005 0,06495359 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,0402005 0,06491066 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,0402005 0,06486779 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,0402005 0,06482497 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,0402005 0,06478221 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,0402005 0,0647395 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,0402005 0,06469686 ! ribosome assembly GO:0042255 18 14 0,000 0,0402005 0,06465426 ! cerebellum development GO:0021549 23 14 0,000 0,0402005 0,06461173 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,0402005 0,06456925 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,0402005 0,06452683 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,0402005 0,06448446 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,0402005 0,06444214 ! NADP metabolic process GO:0006739 24 14 0,000 0,0402005 0,06439989 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,0402005 0,06435769 ! oxygen transport GO:0015671 22 14 0,000 0,0402005 0,06431554 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0402005 0,06427345 ! male genitalia development GO:0030539 26 14 0,000 0,0402005 0,06423141 ! regulation of RNA stability GO:0043487 33 14 0,000 0,0402005 0,06418943 ! regulation of axon extension GO:0030516 43 14 0,000 0,0402005 0,0641475 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,0402005 0,06410563 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04300994 0,06854095 ! lactation GO:0007595 30 15 0,000 0,04300994 0,06849627 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,04300994 0,06845164 ! reproductive cellular process GO:0048610 22 15 0,000 0,04300994 0,06840708 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04300994 0,06836257 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04300994 0,06831812 ! superoxide anion generation GO:0042554 22 15 0,000 0,04300994 0,06827373 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04300994 0,0682294 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,04300994 0,06818512 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04300994 0,0681409 ! copper ion transport GO:0006825 22 15 0,000 0,04300994 0,06809674 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04300994 0,06805264 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04300994 0,06800859 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04300994 0,0679646 ! sulfate transport GO:0008272 27 15 0,000 0,04300994 0,06792067 ! response to cAMP GO:0051591 25 15 0,000 0,04300994 0,06787679 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04300994 0,06783297 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04300994 0,06778921 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,04300994 0,0677455 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04300994 0,06770185 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04300994 0,06765826 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04300994 0,06761472 ! vesicle coating GO:0006901 38 15 0,000 0,04300994 0,06757124 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,04300994 0,06752781 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04300994 0,06748444 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04300994 0,06744113 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04300994 0,06739787 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04300994 0,06735466 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04300994 0,06731151 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04300994 0,06726842 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04300994 0,06722538 ! histone deacetylation GO:0016575 24 15 0,000 0,04300994 0,0671824 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04300994 0,06713947 ! water homeostasis GO:0030104 28 15 0,000 0,04300994 0,0670966 ! cofactor transport GO:0051181 30 15 0,000 0,04300994 0,06705378 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04300994 0,06701102 ! muscle maintenance GO:0046716 26 15 0,000 0,04300994 0,06696831 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04300994 0,06692565 ! intestinal absorption GO:0050892 31 15 0,000 0,04300994 0,06688305 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04300994 0,0668405 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04300994 0,06679801 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04300994 0,06675557 ! cell killing GO:0001906 32 15 0,000 0,04300994 0,06671319 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04300994 0,06667086 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,04300994 0,06662858 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04300994 0,06658636 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04300994 0,06654419 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04300994 0,06650207 ! actin filament polymerization GO:0030041 27 15 0,000 0,04300994 0,06646001 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04300994 0,066418 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,04581122 0,07069919 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04581122 0,07065456 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04581122 0,07060998 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04581122 0,07056546 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04581122 0,070521 ! bone remodeling GO:0046849 28 16 0,000 0,04581122 0,07047659 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04581122 0,07043223 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04581122 0,07038794 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04581122 0,0703437 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04581122 0,07029951 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04581122 0,07025538 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04581122 0,0702113 ! startle response GO:0001964 28 16 0,000 0,04581122 0,07016729 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04581122 0,07012332 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04581122 0,07007941 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04581122 0,07003556 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04581122 0,06999176 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04581122 0,06994801 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04581122 0,06990432 ! pituitary gland development GO:0021983 30 16 0,000 0,04581122 0,06986069 ! response to osmotic stress GO:0006970 27 16 0,000 0,04581122 0,06981711 ! lysosomal transport GO:0007041 31 16 0,000 0,04581122 0,06977358 ! fructose metabolic process GO:0006000 25 16 0,000 0,04581122 0,06973011 ! L-amino acid transport GO:0015807 33 16 0,000 0,04581122 0,06968669 ! stem cell development GO:0048864 46 16 0,000 0,04581122 0,06964332 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04581122 0,06960001 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04581122 0,06955676 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04581122 0,06951355 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04581122 0,0694704 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04581122 0,06942731 ! axon cargo transport GO:0008088 46 16 0,000 0,04581122 0,06938427 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04581122 0,06934128 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04581122 0,06929834 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,04581122 0,06925546 ! DNA replication initiation GO:0006270 28 16 0,000 0,04581122 0,06921263 ! neuron recognition GO:0008038 40 16 0,000 0,04581122 0,06916985 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04581122 0,06912713 ! tissue regeneration GO:0042246 27 16 0,000 0,04581122 0,06908446 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04581122 0,06904184 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04581122 0,06899927 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,04581122 0,06895676 ! biomineral formation GO:0031214 22 16 0,000 0,04581122 0,0689143 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04581122 0,06887189 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04581122 0,06882953 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04581122 0,06878723 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04581122 0,06874498 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04581122 0,06870277 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04581122 0,06866063 ! peptide hormone processing GO:0016486 27 16 0,000 0,04581122 0,06861853 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04860439 0,07275768 ! metencephalon development GO:0022037 32 17 0,000 0,04860439 0,07271312 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,04860439 0,07266862 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,04860439 0,07262418 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04860439 0,07257978 ! signal complex assembly GO:0007172 47 17 0,000 0,04860439 0,07253545 ! filopodium assembly GO:0046847 42 17 0,000 0,04860439 0,07249116 ! endothelial cell migration GO:0043542 31 17 0,000 0,04860439 0,07244694 ! gene silencing by RNA GO:0031047 38 17 0,000 0,04860439 0,07240276 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04860439 0,07235864 ! glial cell development GO:0021782 28 17 0,000 0,04860439 0,07231457 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04860439 0,07227056 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04860439 0,0722266 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,04860439 0,07218269 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,04860439 0,07213884 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,04860439 0,07209504 ! myoblast differentiation GO:0045445 50 17 0,000 0,04860439 0,07205129 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,04860439 0,0720076 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,04860439 0,07196396 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04860439 0,07192037 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,04860439 0,07187683 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04860439 0,07183335 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,04860439 0,07178992 ! NAD metabolic process GO:0019674 33 17 0,000 0,04860439 0,07174654 ! membrane budding GO:0006900 42 17 0,000 0,04860439 0,07170322 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04860439 0,07165994 ! regulation of protein binding GO:0043393 33 17 0,000 0,04860439 0,07161672 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04860439 0,07157355 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04860439 0,07153044 ! genitalia development GO:0048806 32 17 0,000 0,04860439 0,07148737 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,04860439 0,07144436 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,04860439 0,0714014 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04860439 0,07135849 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04860439 0,07131563 ! steroid catabolic process GO:0006706 34 17 0,000 0,04860439 0,07127283 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,04860439 0,07123007 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04860439 0,07118737 ! gas transport GO:0015669 26 17 0,000 0,04860439 0,07114471 ! organic cation transport GO:0015695 32 17 0,000 0,04860439 0,07110211 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,04860439 0,07105956 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04860439 0,07101706 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04860439 0,07097461 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,05138946 0,07499668 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,05138946 0,07495191 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,05138946 0,07490719 ! limbic system development GO:0021761 40 18 0,000 0,05138946 0,07486252 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05138946 0,07481791 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,05138946 0,07477335 ! adult walking behavior GO:0007628 36 18 0,000 0,05138946 0,07472884 ! patterning of blood vessels GO:0001569 43 18 0,000 0,05138946 0,07468438 ! heart looping GO:0001947 34 18 0,000 0,05138946 0,07463998 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,05138946 0,07459563 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,05138946 0,07455134 ! centrosome cycle GO:0007098 26 18 0,000 0,05138946 0,07450709 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,05138946 0,0744629 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,05138946 0,07441876 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,05138946 0,07437467 ! glycine metabolic process GO:0006544 30 18 0,000 0,05138946 0,07433064 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05138946 0,07428666 ! response to retinoic acid GO:0032526 31 18 0,000 0,05138946 0,07424273 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,05138946 0,07419885 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,05138946 0,07415502 ! DNA integration GO:0015074 32 18 0,000 0,05138946 0,07411125 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,05138946 0,07406752 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,05138946 0,07402385 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,05138946 0,07398023 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,05138946 0,07393666 ! neural crest cell migration GO:0001755 41 18 0,000 0,05138946 0,07389314 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,05138946 0,07384968 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,05138946 0,07380626 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,05138946 0,0737629 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,05138946 0,07371958 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,05138946 0,07367632 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,05138946 0,07363311 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,05138946 0,07358995 ! detection of bacterium GO:0016045 22 18 0,000 0,05138946 0,07354684 ! nerve development GO:0021675 34 18 0,000 0,05138946 0,07350378 ! defense response to virus GO:0051607 43 18 0,000 0,05138946 0,07346077 ! microspike assembly GO:0030035 46 18 0,000 0,05138946 0,07341781 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,05138946 0,0733749 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05416645 0,07729477 ! positive regulation of translation GO:0045727 31 19 0,000 0,05416645 0,07724965 ! negative regulation of defense response GO:0031348 27 19 0,000 0,05416645 0,07720458 ! neuron maturation GO:0042551 46 19 0,000 0,05416645 0,07715956 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,05416645 0,0771146 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,05416645 0,07706968 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05416645 0,07702482 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05416645 0,07698002 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,05416645 0,07693526 ! inositol metabolic process GO:0006020 33 19 0,000 0,05416645 0,07689056 ! memory GO:0007613 34 19 0,000 0,05416645 0,0768459 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05416645 0,0768013 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05416645 0,07675676 GO:0042744|hydrogen peroxide catabolic process, ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05416645 0,07671226 ! cerebral cortex development GO:0021987 40 19 0,000 0,05416645 0,07666781 ! pigmentation during development GO:0048066 42 19 0,000 0,05416645 0,07662342 ! response to vitamin A GO:0033189 32 19 0,000 0,05416645 0,07657908 ! heme metabolic process GO:0042168 40 19 0,000 0,05416645 0,07653479 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05416645 0,07649055 ! response to fungus GO:0009620 26 19 0,000 0,05416645 0,07644636 ! peptide cross-linking GO:0018149 39 19 0,000 0,05416645 0,07640222 ! protein export from nucleus GO:0006611 40 19 0,000 0,05416645 0,07635813 ! heart process GO:0003015 32 19 0,000 0,05416645 0,0763141 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05416645 0,07627011 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05416645 0,07622618 ! visual learning GO:0008542 38 19 0,000 0,05416645 0,0761823 ! cellular pigmentation GO:0033059 37 19 0,000 0,05416645 0,07613846 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05416645 0,07609468 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05416645 0,07605095 ! vitamin transport GO:0051180 31 19 0,000 0,05416645 0,07600726 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05416645 0,07596363 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05416645 0,07592005 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05416645 0,07587652 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05416645 0,07583304 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05416645 0,0757896 ! cilium assembly GO:0042384 38 19 0,000 0,05416645 0,07574622 ! peptide hormone secretion GO:0030072 32 19 0,000 0,05416645 0,07570289 ! protein secretion GO:0009306 45 20 0,000 0,0569354 0,07952726 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,0569354 0,07948181 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,0569354 0,07943642 ! positive regulation of ossification GO:0045778 50 20 0,000 0,0569354 0,07939108 ! skin development GO:0043588 42 20 0,000 0,0569354 0,07934579 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,0569354 0,07930056 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,0569354 0,07925537 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,0569354 0,07921024 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,0569354 0,07916515 ! response to vitamin GO:0033273 36 20 0,000 0,0569354 0,07912012 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,0569354 0,07907514 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,0569354 0,07903021 ! bile acid metabolic process GO:0008206 34 20 0,000 0,0569354 0,07898533 ! response to alkaloid GO:0043279 38 20 0,000 0,0569354 0,07894051 ! retinoid metabolic process GO:0001523 34 20 0,000 0,0569354 0,07889573 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,0569354 0,07885101 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,0569354 0,07880633 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,0569354 0,07876171 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,0569354 0,07871713 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,0569354 0,07867261 ! body fluid secretion GO:0007589 33 20 0,000 0,0569354 0,07862814 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,0569354 0,07858371 ! peptide secretion GO:0002790 38 20 0,000 0,0569354 0,07853934 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,0569354 0,07849502 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,0569354 0,07845075 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,0569354 0,07840652 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,0569354 0,07836235 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,0569354 0,07831823 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,0569354 0,07827416 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,0569354 0,07823013 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,0569354 0,07818616 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,0569354 0,07814223 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,0569354 0,07809836 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,0569354 0,07805453 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,0569354 0,07801075 ! regulation of cell killing GO:0031341 46 21 0,000 0,05969631 0,08174781 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,05969631 0,08170201 ! hormone secretion GO:0046879 39 21 0,000 0,05969631 0,08165626 ! cAMP metabolic process GO:0046058 41 21 0,000 0,05969631 0,08161057 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,05969631 0,08156493 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,05969631 0,08151933 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,05969631 0,08147379 ! ovarian follicle development GO:0001541 39 21 0,000 0,05969631 0,0814283 ! smooth muscle contraction GO:0006939 48 21 0,000 0,05969631 0,08138286 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,05969631 0,08133747 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,05969631 0,08129213 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,05969631 0,08124685 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,05969631 0,08120161 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,05969631 0,08115642 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,05969631 0,08111128 ! sensory perception of pain GO:0019233 33 21 0,000 0,05969631 0,0810662 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,05969631 0,08102116 ! diencephalon development GO:0021536 36 21 0,000 0,05969631 0,08097617 ! collagen fibril organization GO:0030199 62 21 0,000 0,05969631 0,08093124 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,05969631 0,08088635 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,05969631 0,08084151 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,05969631 0,08079672 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,05969631 0,08075199 ! collagen catabolic process GO:0030574 29 21 0,000 0,05969631 0,0807073 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,05969631 0,08066266 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,05969631 0,08061807 ! sperm-egg recognition GO:0035036 23 21 0,000 0,05969631 0,08057353 ! actin filament-based movement GO:0030048 47 21 0,000 0,05969631 0,08052904 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,06244922 0,08419616 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,06244922 0,08414972 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,06244922 0,08410333 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,06244922 0,08405699 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,06244922 0,08401071 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,06244922 0,08396447 ! microtubule-based transport GO:0010970 59 22 0,000 0,06244922 0,08391829 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,06244922 0,08387215 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,06244922 0,08382607 ! vacuolar transport GO:0007034 41 22 0,000 0,06244922 0,08378003 ! central nervous system neuron development GO:0021954 47 22 0,000 0,06244922 0,08373405 ! fucose metabolic process GO:0006004 44 22 0,000 0,06244922 0,08368812 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,06244922 0,08364224 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,06244922 0,08359641 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,06244922 0,08355063 ! ureteric bud development GO:0001657 50 22 0,000 0,06244922 0,0835049 ! stem cell differentiation GO:0048863 57 22 0,000 0,06244922 0,08345921 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,06244922 0,08341358 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,06244922 0,083368 ! cytolysis GO:0019835 27 22 0,000 0,06244922 0,08332247 ! renal system process GO:0003014 42 22 0,000 0,06244922 0,08327699 ! vasodilation GO:0042311 40 22 0,000 0,06244922 0,08323156 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,06244922 0,08318617 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,06244922 0,08314084 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,06244922 0,08309556 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,06244922 0,08305032 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,06244922 0,08300514 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,06244922 0,08296 ! sarcomere organization GO:0045214 32 22 0,000 0,06244922 0,08291492 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,06244922 0,08286988 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,06244922 0,08282489 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,06244922 0,08277995 ! gut development GO:0048565 44 22 0,000 0,06244922 0,08273506 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,06244922 0,08269021 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,06244922 0,08264542 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,06244922 0,08260067 ! protein stabilization GO:0050821 41 22 0,000 0,06244922 0,08255598 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,06519415 0,08613807 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,06519415 0,08609151 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06519415 0,086045 ! gluconeogenesis GO:0006094 38 23 0,000 0,06519415 0,08599854 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06519415 0,08595213 ! viral genome replication GO:0019079 44 23 0,000 0,06519415 0,08590577 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06519415 0,08585946 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06519415 0,0858132 ! regeneration GO:0031099 42 23 0,000 0,06519415 0,08576699 ! axis specification GO:0009798 43 23 0,000 0,06519415 0,08572083 ! visual behavior GO:0007632 46 23 0,000 0,06519415 0,08567472 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,06519415 0,08562866 ! response to ethanol GO:0045471 47 23 0,000 0,06519415 0,08558264 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06519415 0,08553668 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,06519415 0,08549077 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06519415 0,0854449 ! peroxisome organization GO:0007031 43 23 0,000 0,06519415 0,08539909 ! lysosome organization GO:0007040 47 23 0,000 0,06519415 0,08535332 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,06519415 0,08530761 ! vesicle targeting GO:0006903 49 23 0,000 0,06519415 0,08526194 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06519415 0,08521632 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06519415 0,08517075 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,06519415 0,08512523 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06519415 0,08507975 ! DNA modification GO:0006304 36 23 0,000 0,06519415 0,08503433 ! fatty acid transport GO:0015908 47 23 0,000 0,06519415 0,08498895 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,06519415 0,08494363 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06519415 0,08489835 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06519415 0,08485312 ! hormone transport GO:0009914 41 23 0,000 0,06519415 0,08480793 ! cell-cell recognition GO:0009988 28 23 0,000 0,06519415 0,0847628 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06519415 0,08471771 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06519415 0,08467267 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,06519415 0,08462768 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,06793111 0,08813367 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,06793111 0,08808689 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,06793111 0,08804016 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,06793111 0,08799348 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,06793111 0,08794685 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,06793111 0,08790027 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,06793111 0,08785374 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,06793111 0,08780725 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,06793111 0,08776082 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,06793111 0,08771443 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,06793111 0,0876681 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,06793111 0,08762181 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,06793111 0,08757557 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,06793111 0,08752938 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,06793111 0,08748324 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,06793111 0,08743715 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,06793111 0,08739111 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,06793111 0,08734511 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,06793111 0,08729916 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,06793111 0,08725326 ! membrane depolarization GO:0051899 45 24 0,000 0,06793111 0,08720741 ! pallium development GO:0021543 56 24 0,000 0,06793111 0,08716161 ! oogenesis GO:0048477 44 24 0,000 0,06793111 0,08711586 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,06793111 0,08707015 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,06793111 0,08702449 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,06793111 0,08697888 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,06793111 0,08693332 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,06793111 0,08688781 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,06793111 0,08684234 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,06793111 0,08679692 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,06793111 0,08675155 ! regulation of amine transport GO:0051952 41 24 0,000 0,06793111 0,08670622 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,07066014 0,09014242 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,07066014 0,09009537 ! leukocyte adhesion GO:0007159 55 25 0,000 0,07066014 0,09004837 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,07066014 0,09000142 ! phototransduction GO:0007602 37 25 0,000 0,07066014 0,08995452 ! keratinization GO:0031424 37 25 0,000 0,07066014 0,08990767 ! vasculogenesis GO:0001570 49 25 0,000 0,07066014 0,08986087 ! vacuole organization GO:0007033 49 25 0,000 0,07066014 0,08981412 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,07066014 0,08976741 ! receptor metabolic process GO:0043112 53 25 0,000 0,07066014 0,08972075 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,07066014 0,08967415 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,07066014 0,08962759 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,07066014 0,08958108 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,07066014 0,08953461 ! immunoglobulin production GO:0002377 62 25 0,000 0,07066014 0,0894882 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,07066014 0,08944183 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,07066014 0,08939551 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,07066014 0,08934924 ! liver development GO:0001889 55 25 0,000 0,07066014 0,08930302 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,07338126 0,09269412 ! initiation of viral infection GO:0019059 60 26 0,000 0,07338126 0,09264621 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,07338126 0,09259836 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,07338126 0,09255055 ! molting cycle process GO:0022404 52 26 0,000 0,07338126 0,0925028 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,07338126 0,09245509 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,07338126 0,09240743 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,07338126 0,09235982 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,07338126 0,09231227 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,07338126 0,09226476 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,07338126 0,09221729 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,07338126 0,09216988 ! digestive system process GO:0022600 49 26 0,000 0,07338126 0,09212252 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,07338126 0,0920752 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,07338126 0,09202794 ! osteoblast differentiation GO:0001649 63 26 0,000 0,07338126 0,09198072 ! neural crest cell development GO:0014032 59 26 0,000 0,07338126 0,09193355 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,07338126 0,09188643 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,07338126 0,09183935 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,07338126 0,09179233 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,07338126 0,09174535 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,07338126 0,09169842 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,07338126 0,09165154 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,07338126 0,09160471 ! blastocyst development GO:0001824 50 26 0,000 0,07338126 0,09155793 ! telomere organization GO:0032200 46 26 0,000 0,07338126 0,09151119 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,07338126 0,0914645 ! neural tube closure GO:0001843 58 26 0,000 0,07338126 0,09141786 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,07338126 0,09137126 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,07338126 0,09132472 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,07609449 0,09465317 ! embryonic pattern specification GO:0009880 49 27 0,000 0,07609449 0,094605 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,07609449 0,09455688 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,07609449 0,09450881 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,07609449 0,09446079 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,07609449 0,09441281 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,07609449 0,09436489 ! iron ion transport GO:0006826 65 27 0,000 0,07609449 0,09431701 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,07609449 0,09426918 ! superoxide metabolic process GO:0006801 41 27 0,000 0,07609449 0,0942214 ! tube lumen formation GO:0035148 59 27 0,000 0,07609449 0,09417367 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,07609449 0,09412599 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,07609449 0,09407836 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,07609449 0,09403077 ! response to toxin GO:0009636 49 27 0,000 0,07609449 0,09398323 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,07609449 0,09393574 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,07609449 0,0938883 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,07609449 0,0938409 ! leukocyte proliferation GO:0070661 59 27 0,000 0,07609449 0,09379356 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,07879984 0,09707918 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,07879984 0,09703025 ! protein amino acid acylation GO:0043543 59 28 0,000 0,07879984 0,09698137 ! vesicle docking GO:0048278 55 28 0,000 0,07879984 0,09693254 ! circadian rhythm GO:0007623 56 28 0,000 0,07879984 0,09688375 ! fat cell differentiation GO:0045444 57 28 0,000 0,07879984 0,09683502 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,07879984 0,09678633 ! sperm motility GO:0030317 37 28 0,000 0,07879984 0,0967377 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,07879984 0,09668911 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,07879984 0,09664057 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,07879984 0,09659208 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,07879984 0,09654364 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,07879984 0,09649525 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,07879984 0,0964469 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,07879984 0,09639861 ! glutathione metabolic process GO:0006749 42 28 0,000 0,07879984 0,09635036 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,07879984 0,09630216 ! lipid oxidation GO:0034440 48 28 0,000 0,07879984 0,09625401 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,07879984 0,09620591 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,08149735 0,09944957 ! translational initiation GO:0006413 66 29 0,000 0,08149735 0,09939992 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,08149735 0,09935032 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,08149735 0,09930077 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,08149735 0,09925127 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,08149735 0,09920181 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,08149735 0,09915241 ! primary neural tube formation GO:0014020 61 29 0,000 0,08149735 0,09910306 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,08149735 0,09905375 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,08149735 0,09900449 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,08149735 0,09895529 ! somitogenesis GO:0001756 52 29 0,000 0,08149735 0,09890613 ! synaptogenesis GO:0007416 46 29 0,000 0,08149735 0,09885702 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,08149735 0,09880796 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,08149735 0,09875895 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,08149735 0,09870998 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,08149735 0,09866107 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,08418704 0,10186674 ! phenol metabolic process GO:0018958 56 30 0,000 0,08418704 0,10181631 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,08418704 0,10176593 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,08418704 0,1017156 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,08418704 0,10166532 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,08418704 0,10161509 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,08418704 0,10156491 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,08418704 0,10151478 ! acute-phase response GO:0006953 50 30 0,000 0,08418704 0,1014647 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,08418704 0,10141467 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,08418704 0,10136469 ! myofibril assembly GO:0030239 50 30 0,000 0,08418704 0,10131475 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,08418704 0,10126487 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,08418704 0,10121503 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,08418704 0,10116525 ! cell fate determination GO:0001709 64 30 0,000 0,08418704 0,10111551 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,08418704 0,10106582 ! phospholipid transport GO:0015914 65 30 0,000 0,08418704 0,10101618 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,08418704 0,10096659 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,08418704 0,10091705 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,08418704 0,10086756 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,08418704 0,10081811 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,08418704 0,10076871 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,08686893 0,10392791 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,08686893 0,10387704 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,08686893 0,10382622 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,08686893 0,10377545 ! regulation of innate immune response GO:0045088 57 31 0,000 0,08686893 0,10372473 ! ovulation cycle process GO:0022602 55 31 0,000 0,08686893 0,10367406 ! peptide transport GO:0015833 60 31 0,000 0,08686893 0,10362344 ! male gonad development GO:0008584 56 31 0,000 0,08686893 0,10357286 ! iron ion homeostasis GO:0055072 60 31 0,000 0,08686893 0,10352234 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,08686893 0,10347187 ! detection of light stimulus GO:0009583 44 31 0,000 0,08686893 0,10342144 ! natural killer cell activation GO:0030101 50 31 0,000 0,08686893 0,10337107 ! cofactor catabolic process GO:0051187 54 31 0,000 0,08686893 0,10332074 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,08686893 0,10327046 ! eye morphogenesis GO:0048592 65 31 0,000 0,08686893 0,10322023 ! response to heat GO:0009408 54 31 0,000 0,08686893 0,10317005 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,08686893 0,10311992 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,08954304 0,10624266 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,08954304 0,10619109 ! collagen metabolic process GO:0032963 49 32 0,000 0,08954304 0,10613957 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,08954304 0,10608809 ! spindle organization GO:0007051 50 32 0,000 0,08954304 0,10603667 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,08954304 0,10598529 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,08954304 0,10593397 ! metanephros development GO:0001656 81 32 0,000 0,08954304 0,10588269 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,08954304 0,10583147 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,08954304 0,10578029 ! muscle cell development GO:0055001 52 32 0,000 0,08954304 0,10572917 ! mesoderm formation GO:0001707 73 32 0,000 0,08954304 0,10567809 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,08954304 0,10562706 ! ovulation cycle GO:0042698 57 32 0,000 0,08954304 0,10557608 ! BMP signaling pathway GO:0030509 71 32 0,000 0,08954304 0,10552515 ! hindbrain development GO:0030902 65 32 0,000 0,08954304 0,10547427 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,08954304 0,10542344 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,08954304 0,10537266 ! gene silencing GO:0016458 71 32 0,000 0,08954304 0,10532193 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,09220939 0,10840594 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,09220939 0,1083538 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,09220939 0,1083017 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,09220939 0,10824966 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,09220939 0,10819767 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,09220939 0,10814573 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,09220939 0,10809383 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,09220939 0,10804199 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,09220939 0,10799019 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,09220939 0,10793845 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,09220939 0,10788676 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,09486801 0,11094426 ! post-embryonic development GO:0009791 76 34 0,000 0,09486801 0,11089117 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,09486801 0,11083814 ! cholesterol transport GO:0030301 62 34 0,000 0,09486801 0,11078516 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,09486801 0,11073223 ! spliceosome assembly GO:0000245 75 34 0,000 0,09486801 0,11067935 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,09486801 0,11062652 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,09486801 0,11057374 ! formation of primary germ layer GO:0001704 76 34 0,000 0,09486801 0,11052101 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,09486801 0,11046833 ! adult locomotory behavior GO:0008344 62 34 0,000 0,09486801 0,1104157 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,09751892 0,11344701 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,09751892 0,11339301 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,09751892 0,11333907 ! membrane docking GO:0022406 69 35 0,000 0,09751892 0,11328517 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,09751892 0,11323133 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,09751892 0,11317754 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,09751892 0,1131238 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,09751892 0,11307011 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,09751892 0,11301647 ! ceramide metabolic process GO:0006672 72 35 0,000 0,09751892 0,11296288 ! telencephalon development GO:0021537 81 35 0,000 0,09751892 0,11290935 ! sterol transport GO:0015918 63 35 0,000 0,09751892 0,11285586 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,09751892 0,11280242 ! placenta development GO:0001890 53 35 0,000 0,09751892 0,11274904 ! vesicle localization GO:0051648 70 35 0,000 0,09751892 0,1126957 ! regulation of muscle development GO:0048634 82 36 0,000 0,10016214 0,11569556 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,10016214 0,11564088 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,10016214 0,11558625 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,10016214 0,11553168 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,10016214 0,11547716 ! positive regulation of cell development GO:0010720 85 36 0,000 0,10016214 0,11542269 ! protein targeting to membrane GO:0006612 75 36 0,000 0,10016214 0,11536827 ! regulation of proteolysis GO:0030162 77 36 0,000 0,10016214 0,1153139 ! aerobic respiration GO:0009060 56 36 0,000 0,10016214 0,11525959 ! cytokine production GO:0001816 68 36 0,000 0,10016214 0,11520532 ! embryonic organ development GO:0048568 67 36 0,000 0,10016214 0,11515111 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,10016214 0,11509694 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,10016214 0,11504283 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,10279769 0,11801445 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,10279769 0,11795902 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,10279769 0,11790364 ! odontogenesis GO:0042476 74 37 0,000 0,10279769 0,11784831 ! actomyosin structure organization GO:0031032 68 37 0,000 0,10279769 0,11779304 ! tissue remodeling GO:0048771 78 37 0,000 0,10279769 0,11773781 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,10279769 0,11768264 ! female gonad development GO:0008585 71 37 0,000 0,10279769 0,11762752 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,10279769 0,11757245 ! meiosis I GO:0007127 74 38 0,000 0,10542559 0,12052163 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,10542559 0,12046526 ! organic anion transport GO:0015711 82 38 0,000 0,10542559 0,12040894 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,10542559 0,12035268 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,10542559 0,12029646 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,10542559 0,1202403 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,10542559 0,12018419 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,10542559 0,12012814 ! regulation of protein stability GO:0031647 77 38 0,000 0,10542559 0,12007213 ! spermatid development GO:0007286 69 38 0,000 0,10542559 0,12001618 ! pigment metabolic process GO:0042440 87 38 0,000 0,10542559 0,11996028 ! neural tube formation GO:0001841 79 38 0,000 0,10542559 0,11990443 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,10804588 0,1228274 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,10804588 0,12277027 ! negative regulation of binding GO:0051100 71 39 0,000 0,10804588 0,12271319 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,10804588 0,12265617 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,10804588 0,1225992 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,10804588 0,12254228 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,10804588 0,12248542 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,10804588 0,12242861 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,11065856 0,12533095 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,11065856 0,12527287 ! learning GO:0007612 82 40 0,000 0,11065856 0,12521485 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,11065856 0,12515688 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,11065856 0,12509896 ! lipid homeostasis GO:0055088 75 40 0,000 0,11065856 0,1250411 ! mismatch repair GO:0006298 58 40 0,000 0,11065856 0,12498329 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,11065856 0,12492553 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,11065856 0,12486783 ! RNA export from nucleus GO:0006405 61 41 0,000 0,11326366 0,12774844 ! mRNA catabolic process GO:0006402 79 41 0,000 0,11326366 0,12768949 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,11326366 0,12763059 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,11326366 0,12757175 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,11326366 0,12751296 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,11326366 0,12745422 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,11326366 0,12739554 ! feeding behavior GO:0007631 69 41 0,000 0,11326366 0,12733691 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,11326366 0,12727834 ! mesenchymal cell development GO:0014031 94 41 0,000 0,11326366 0,12721982 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,11326366 0,12716136 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,11326366 0,12710295 ! spermatid differentiation GO:0048515 73 41 0,000 0,11326366 0,12704459 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,11326366 0,12698629 ! RNA modification GO:0009451 64 41 0,000 0,11326366 0,12692803 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,1158612 0,12977942 ! ear morphogenesis GO:0042471 64 42 0,000 0,1158612 0,12971994 ! organic ether metabolic process GO:0018904 59 42 0,000 0,1158612 0,12966052 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,1158612 0,12960115 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,1158612 0,12954184 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,1158612 0,12948258 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,1158612 0,12942337 ! cytokinesis GO:0000910 84 42 0,000 0,1158612 0,12936422 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,1158612 0,12930512 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,11845121 0,1321353 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,11845121 0,13207499 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,11845121 0,13201474 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,11845121 0,13195454 ! regulation of tube size GO:0035150 76 43 0,000 0,11845121 0,13189439 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,11845121 0,13183431 ! glucose transport GO:0015758 66 43 0,000 0,11845121 0,13177427 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,11845121 0,13171429 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,11845121 0,13165437 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,11845121 0,1315945 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,11845121 0,13153468 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,11845121 0,13147492 ! segmentation GO:0035282 78 43 0,000 0,11845121 0,13141521 ! ion transmembrane transport GO:0034220 79 43 0,000 0,11845121 0,13135556 ! neuron migration GO:0001764 85 43 0,000 0,11845121 0,13129596 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,1210337 0,13409766 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,1210337 0,13403687 ! hexose transport GO:0008645 68 44 0,000 0,1210337 0,13397614 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,1210337 0,13391546 ! striated muscle contraction GO:0006941 85 44 0,000 0,1210337 0,13385484 ! phagocytosis GO:0006909 105 44 0,000 0,1210337 0,13379427 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,1210337 0,13373375 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,1236087 0,1365172 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,1236087 0,13645552 ! biopolymer methylation GO:0043414 91 45 0,000 0,1236087 0,13639388 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,1236087 0,1363323 ! female gamete generation GO:0007292 71 45 0,000 0,1236087 0,13627078 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,1236087 0,13620932 ! polyol metabolic process GO:0019751 77 45 0,000 0,1236087 0,13614791 ! developmental growth GO:0048589 88 45 0,000 0,1236087 0,13608655 ! maintenance of location in cell GO:0051651 101 45 0,000 0,1236087 0,13602525 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,12617623 0,13878817 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,12617623 0,13872571 ! glycolysis GO:0006096 71 46 0,000 0,12617623 0,13866331 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,12617623 0,13860096 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,12617623 0,13853866 ! pigmentation GO:0043473 103 46 0,000 0,12617623 0,13847643 ! neural tube development GO:0021915 91 47 0,000 0,12873631 0,14122263 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,13128896 0,14395822 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,13128896 0,14389364 ! cellular component disassembly GO:0022411 89 48 0,000 0,13128896 0,14382911 ! endosome transport GO:0016197 127 48 0,000 0,13128896 0,14376465 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,13128896 0,14370023 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,13128896 0,14363588 ! male sex differentiation GO:0046661 93 48 0,000 0,13128896 0,14357159 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,13128896 0,14350735 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,13128896 0,14344317 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,13128896 0,14337905 ! methylation GO:0032259 97 48 0,000 0,13128896 0,14331498 ! response to calcium ion GO:0051592 94 49 0,000 0,1338342 0,14602812 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,1338342 0,14596293 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,1338342 0,14589779 ! protein homooligomerization GO:0051260 84 49 0,000 0,1338342 0,14583272 ! regulation of ion transport GO:0043269 86 50 0,000 0,13637206 0,14853185 ! endocrine system development GO:0035270 109 50 0,000 0,13637206 0,14846566 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,13637206 0,14839953 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,13637206 0,14833345 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,13637206 0,14826744 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,13637206 0,14820148 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,13637206 0,14813559 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,13890255 0,1508173 ! viral infectious cycle GO:0019058 104 51 0,000 0,13890255 0,1507503 ! response to temperature stimulus GO:0009266 84 51 0,000 0,13890255 0,15068336 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,13890255 0,15061648 ! positive regulation of binding GO:0051099 88 52 0,000 0,1414257 0,15328438 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,1414257 0,1532164 ! Notch signaling pathway GO:0007219 111 52 0,000 0,1414257 0,15314849 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,1414257 0,15308063 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,1414257 0,15301284 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,1414257 0,1529451 ! excretion GO:0007588 87 52 0,000 0,1414257 0,15287743 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,1414257 0,15280981 ! histone modification GO:0016570 104 52 0,000 0,1414257 0,15274226 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,1414257 0,15267476 ! amino acid activation GO:0043038 98 52 0,000 0,1414257 0,15260733 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,14394153 0,15525349 ! inner ear development GO:0048839 89 53 0,000 0,14394153 0,15518497 ! chromatin remodeling GO:0006338 122 53 0,000 0,14394153 0,15511652 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,14394153 0,15504813 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,14394153 0,15497979 ! vesicle organization GO:0016050 127 53 0,000 0,14394153 0,15491152 ! regulation of translational initiation GO:0006446 87 54 0,000 0,14645005 0,15754182 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,14645005 0,15747248 ! neuromuscular process GO:0050905 107 54 0,000 0,14645005 0,1574032 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,14645005 0,15733398 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,14645005 0,15726483 ! covalent chromatin modification GO:0016569 115 54 0,000 0,14645005 0,15719573 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,14645005 0,15712669 ! regulation of cell shape GO:0008360 142 54 0,000 0,14645005 0,15705772 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,14645005 0,1569888 ! RNA catabolic process GO:0006401 103 55 0,000 0,1489513 0,15960001 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,1489513 0,15953004 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,1489513 0,15946013 ! cell recognition GO:0008037 98 55 0,000 0,1489513 0,15939028 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,1489513 0,1593205 ! cell maturation GO:0048469 107 55 0,000 0,1489513 0,15925077 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,1489513 0,15918111 ! glucose catabolic process GO:0006007 88 56 0,000 0,15144528 0,16177561 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,15144528 0,16170491 ! chloride transport GO:0006821 102 57 0,000 0,15393203 0,16428831 ! regulation of actin filament length GO:0030832 118 58 0,000 0,15641156 0,16686177 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,15641156 0,16678893 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,15641156 0,16671616 ! gastrulation GO:0007369 122 58 0,000 0,15641156 0,16664346 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,15641156 0,16657081 ! maintenance of location GO:0051235 124 58 0,000 0,15641156 0,16649823 ! nuclear export GO:0051168 110 59 0,000 0,15888389 0,16905634 ! establishment of organelle localization GO:0051656 122 59 0,000 0,15888389 0,16898274 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,16134905 0,17152991 ! regulation of endocytosis GO:0030100 104 60 0,000 0,16134905 0,1714553 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,16134905 0,17138075 ! adult behavior GO:0030534 104 60 0,000 0,16134905 0,17130627 ! kidney development GO:0001822 133 60 0,000 0,16134905 0,17123185 ! positive regulation of secretion GO:0051047 110 61 0,000 0,16380705 0,17376493 ! regulation of cellular component size GO:0032535 125 61 0,000 0,16380705 0,17368951 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,16380705 0,17361415 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,16380705 0,17353887 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,16380705 0,17346364 ! camera-type eye development GO:0043010 126 61 0,000 0,16380705 0,17338849 ! proton transport GO:0015992 117 61 0,000 0,16380705 0,17331339 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,16625792 0,17583034 ! tRNA processing GO:0008033 102 62 0,000 0,16625792 0,17575426 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,16870167 0,17826046 ! mesoderm development GO:0007498 128 63 0,000 0,16870167 0,17818339 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,16870167 0,17810638 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,16870167 0,17802945 ! hydrogen transport GO:0006818 121 64 0,000 0,17113832 0,18052285 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,17113832 0,18044494 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,17113832 0,18036709 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,17356791 0,18284881 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,17356791 0,18277 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,17356791 0,18269125 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,17356791 0,18261257 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,17356791 0,18253396 ! ear development GO:0043583 114 66 0,000 0,17599044 0,185002 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,17599044 0,18492243 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,17599044 0,18484292 ! gonad development GO:0008406 115 66 0,000 0,17599044 0,18476349 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,17840593 0,18721894 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,17840593 0,18713856 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,17840593 0,18705824 ! secondary metabolic process GO:0019748 125 67 0,000 0,17840593 0,18697799 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,17840593 0,18689781 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,18081442 0,18933974 ! hexose catabolic process GO:0019320 113 68 0,000 0,18081442 0,18925862 ! extracellular matrix organization GO:0030198 146 68 0,000 0,18081442 0,18917757 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,18081442 0,18909659 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,18081442 0,18901567 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,18081442 0,18893483 ! adaptive immune response GO:0002250 126 68 0,000 0,18081442 0,18885405 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,18081442 0,18877334 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,18321591 0,19119883 ! urogenital system development GO:0001655 149 69 0,000 0,18321591 0,19111719 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,18321591 0,19103562 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,18321591 0,19095412 ! developmental maturation GO:0021700 128 69 0,000 0,18321591 0,19087269 ! cell redox homeostasis GO:0045454 114 70 0,000 0,18561043 0,19328486 ! germ cell development GO:0007281 133 70 0,000 0,18561043 0,1932025 ! activation of immune response GO:0002253 120 70 0,000 0,18561043 0,19312022 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,18561043 0,19303801 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,18799799 0,19543791 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,18799799 0,19535478 ! appendage morphogenesis GO:0035107 150 72 0,000 0,19037863 0,19774447 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,19037863 0,19766043 ! actin filament organization GO:0007015 167 72 0,000 0,19037863 0,19757646 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,19037863 0,19749256 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,19037863 0,19740874 ! appendage development GO:0048736 151 73 0,000 0,19275235 0,19978531 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,19275235 0,19970059 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,19275235 0,19961593 ! regulation of immune effector process GO:0002697 156 73 0,000 0,19275235 0,19953135 ! acute inflammatory response GO:0002526 118 74 0,000 0,19511918 0,20189587 ! amino acid transport GO:0006865 148 74 0,000 0,19511918 0,20181039 ! organelle localization GO:0051640 155 74 0,000 0,19511918 0,20172499 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,19747913 0,20407848 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,19747913 0,20399218 ! reproductive structure development GO:0048608 131 75 0,000 0,19747913 0,20390597 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,19747913 0,20381982 ! eye development GO:0001654 155 75 0,000 0,19747913 0,20373375 ! rhythmic process GO:0048511 142 75 0,000 0,19747913 0,20364775 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,19983223 0,2059874 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,19983223 0,20590053 ! learning or memory GO:0007611 161 76 0,000 0,19983223 0,20581372 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,19983223 0,20572699 ! regulation of blood pressure GO:0008217 134 76 0,000 0,19983223 0,20564033 ! amine catabolic process GO:0009310 136 77 0,000 0,2021785 0,20796719 ! neurotransmitter transport GO:0006836 142 77 0,000 0,2021785 0,20787966 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,2021785 0,20779221 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,2021785 0,20770483 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,2021785 0,20761752 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,20451796 0,20993167 ! antigen processing and presentation GO:0019882 117 78 0,000 0,20451796 0,2098435 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,20685062 0,2121478 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,20685062 0,21205877 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,20685062 0,21196982 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,20685062 0,21188095 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,2091765 0,21417359 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,2091765 0,21408387 ! meiosis GO:0007126 143 81 0,000 0,21149563 0,21636676 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,21149563 0,2162762 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,21380803 0,21854938 ! meiotic cell cycle GO:0051321 144 82 0,000 0,21380803 0,21845797 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,21611371 0,22072148 ! exocytosis GO:0006887 153 83 0,000 0,21611371 0,22062924 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,21611371 0,22053709 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,21611371 0,220445 ! inorganic anion transport GO:0015698 156 83 0,000 0,21611371 0,220353 ! response to metal ion GO:0010038 158 84 0,000 0,21841269 0,22260417 ! response to nutrient GO:0007584 135 84 0,000 0,21841269 0,22251134 ! digestion GO:0007586 130 84 0,000 0,21841269 0,22241859 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,22070499 0,22465929 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,22070499 0,22456572 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,22070499 0,22447223 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,22070499 0,22437881 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,22299064 0,2266082 ! regulation of lyase activity GO:0051339 169 86 0,000 0,22299064 0,22651398 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,22526964 0,22873389 ! alcohol catabolic process GO:0046164 142 87 0,000 0,22526964 0,22863886 ! nucleosome assembly GO:0006334 126 87 0,000 0,22526964 0,22854391 ! cellular respiration GO:0045333 143 88 0,000 0,22754203 0,23075349 ! amine biosynthetic process GO:0009309 146 88 0,000 0,22754203 0,23065775 ! sensory perception of smell GO:0007608 117 88 0,000 0,22754203 0,23056208 ! chromatin assembly GO:0031497 128 88 0,000 0,22754203 0,23046649 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,22754203 0,23037098 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,22980781 0,23256855 ! regulation of DNA binding GO:0051101 167 89 0,000 0,22980781 0,23247225 ! cellular defense response GO:0006968 123 89 0,000 0,22980781 0,23237603 ! regulation of neurological system process GO:0031644 175 89 0,000 0,22980781 0,23227988 ! response to inorganic substance GO:0010035 173 90 0,000 0,23206701 0,23446638 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,23206701 0,23436945 ! response to unfolded protein GO:0006986 139 90 0,000 0,23206701 0,23427261 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,23431965 0,23644895 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,23431965 0,23635132 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,23656574 0,23851841 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,23880531 0,24067713 ! amine transport GO:0015837 181 93 0,000 0,23880531 0,24057789 ! vitamin metabolic process GO:0006766 153 93 0,000 0,23880531 0,24047872 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,24103837 0,24262742 ! female pregnancy GO:0007565 166 94 0,000 0,24103837 0,24252749 ! sterol metabolic process GO:0016125 166 94 0,000 0,24103837 0,24242764 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,24103837 0,24232788 ! nucleosome organization GO:0034728 143 95 0,000 0,24326494 0,24446576 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,24326494 0,24436524 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,24326494 0,2442648 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,24326494 0,24416444 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,24326494 0,24406417 ! sex differentiation GO:0007548 171 96 0,000 0,24548505 0,24619046 ! response to protein stimulus GO:0051789 158 96 0,000 0,24548505 0,24608944 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,2476987 0,2482067 ! forebrain development GO:0030900 210 98 0,000 0,24990592 0,25031577 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,24990592 0,25021318 ! mRNA transport GO:0051028 185 100 0,000 0,25430114 0,2545095 ! positive regulation of immune response GO:0050778 175 100 0,000 0,25430114 0,25440527 ! hormone metabolic process GO:0042445 171 100 0,000 0,25430114 0,25430114