pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6598-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! S phase GO:0051320 8 8 3,000 7,51E-08 1,727E-04 GO:0000084|S phase of mitotic cell cycle, ! pigmentation GO:0043473 74 38 5,000 8,07E-08 9,28E-05 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 3,000 7,5E-07 5,75E-04 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 4,000 9,226E-07 5,305E-04 ! mitotic sister chromatid segregation GO:0000070 45 32 4,000 1,088E-06 5,007E-04 ! sister chromatid segregation GO:0000819 46 33 4,000 1,277E-06 4,894E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 3,427E-06 1,126E-03 ! ATP synthesis coupled electron transport GO:0042773 48 40 4,000 3,427E-06 9,853E-04 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! G2/M transition of mitotic cell cycle GO:0000086 33 21 3,000 6,057E-06 1,548E-03 ! activation of pro-apoptotic gene products GO:0008633 36 21 3,000 6,057E-06 1,393E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 6,636E-06 1,388E-03 ! respiratory electron transport chain GO:0022904 59 47 4,000 7,735E-06 1,483E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 3,000 8,881E-06 1,571E-03 ! negative regulation of phosphorylation GO:0042326 41 23 3,000 8,881E-06 1,459E-03 ! induction of positive chemotaxis GO:0050930 14 8 2,000 1,057E-05 1,621E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 1,257E-05 1,808E-03 GO:0045936|negative regulation of phosphate metabolic process, ! peptidyl-tyrosine modification GO:0018212 37 25 3,000 1,257E-05 1,701E-03 ! negative regulation of protein modification process GO:0031400 50 26 3,000 1,479E-05 1,89E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 1,579E-05 1,912E-03 ! chromosome segregation GO:0007059 83 57 4,000 2,016E-05 2,319E-03 ! protein sumoylation GO:0016925 12 10 2,000 2,246E-05 2,46E-03 ! regulation of positive chemotaxis GO:0050926 17 11 2,000 3,076E-05 3,215E-03 GO:0050927|positive regulation of positive chemotaxis, ! chondrocyte differentiation GO:0002062 17 11 2,000 3,076E-05 3,076E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 3,076E-05 2,947E-03 GO:0010829|negative regulation of glucose transport, ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 3,000 4,428E-05 4,074E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 6,699E-05 5,926E-03 ! blood coagulation GO:0007596 116 75 4,000 7,649E-05 6,516E-03 GO:0050817|coagulation, ! regulation of the force of heart contraction GO:0002026 21 15 2,000 8,338E-05 6,849E-03 ! dopamine metabolic process GO:0042417 30 15 2,000 8,338E-05 6,613E-03 ! cellular respiration GO:0045333 107 79 4,000 9,806E-05 7,518E-03 ! oxidative phosphorylation GO:0006119 105 79 4,000 9,806E-05 7,275E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 1,022E-04 7,345E-03 ! hemostasis GO:0007599 125 81 4,000 1,105E-04 7,698E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 1,236E-04 8,359E-03 ! positive regulation of MAP kinase activity GO:0043406 121 85 4,000 1,388E-04 9,123E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 1,476E-04 9,433E-03 ! pigmentation during development GO:0048066 31 18 2,000 1,476E-04 9,178E-03 ! regulation of glucose import GO:0046324 21 18 2,000 1,476E-04 8,937E-03 GO:0010827|regulation of glucose transport, ! positive regulation of locomotion GO:0040017 35 20 2,000 2,045E-04 0,01206207 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 2,000 2,045E-04 0,01176052 ! electron transport chain GO:0022900 123 94 4,000 2,229E-04 0,01250353 ! regulation of chemotaxis GO:0050920 36 21 2,000 2,376E-04 0,01301196 ! platelet activation GO:0030168 28 21 2,000 2,376E-04 0,01270936 ! regulation of behavior GO:0050795 38 22 2,000 2,74E-04 0,01432082 ! regulation of body fluid levels GO:0050878 154 100 4,000 2,974E-04 0,0152001 ! myelination GO:0042552 35 23 2,000 3,137E-04 0,01568629 ! sleep GO:0030431 11 5 1,000 3,333E-04 0,01630864 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 3,333E-04 0,01596888 ! epithelial cell proliferation GO:0050673 6 5 1,000 3,333E-04 0,01564298 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 3,333E-04 0,01533012 ! valine metabolic process GO:0006573 8 5 1,000 3,333E-04 0,01502953 ! paraxial mesoderm development GO:0048339 9 5 1,000 3,333E-04 0,0147405 ! attachment of GPI anchor to protein GO:0016255 9 5 1,000 3,333E-04 0,01446238 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 1,000 3,333E-04 0,01419456 ! neural tube patterning GO:0021532 6 5 1,000 3,333E-04 0,01393647 ! apical protein localization GO:0045176 6 5 1,000 3,333E-04 0,01368761 ! regulation of sensory perception GO:0051931 6 5 1,000 3,333E-04 0,01344748 GO:0051930|regulation of sensory perception of pain, ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 3,403E-04 0,01349449 ! negative regulation of kinase activity GO:0033673 100 58 3,000 3,639E-04 0,014185 ! regulation of chromosome organization GO:0033044 35 25 2,000 4,04E-04 0,01548663 ! negative regulation of transferase activity GO:0051348 105 61 3,000 4,416E-04 0,01665133 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 1,000 4,98E-04 0,01847387 ! prostate gland development GO:0030850 9 6 1,000 4,98E-04 0,01818063 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 1,000 4,98E-04 0,01789656 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 4,98E-04 0,01762123 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of exocytosis GO:0045921 6 6 1,000 4,98E-04 0,01735424 ! positive regulation of cytokine production during immune response GO:0002720 8 6 1,000 4,98E-04 0,01709522 ! midbrain development GO:0030901 6 6 1,000 4,98E-04 0,01684382 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 4,996E-04 0,01665367 ! catechol metabolic process GO:0009712 43 27 2,000 5,094E-04 0,01673904 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 3,000 5,305E-04 0,01718675 ! phenol metabolic process GO:0018958 44 28 2,000 5,682E-04 0,01814998 ! mesoderm formation GO:0001707 46 28 2,000 5,682E-04 0,01790135 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 5,682E-04 0,01765944 ! ensheathment of neurons GO:0007272 43 28 2,000 5,682E-04 0,01742398 GO:0008366|axon ensheathment, ! formation of primary germ layer GO:0001704 48 29 2,000 6,311E-04 0,01909775 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 6,945E-04 0,0207458 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 6,945E-04 0,02047983 ! asymmetric protein localization GO:0008105 8 7 1,000 6,945E-04 0,02022059 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 1,000 6,945E-04 0,01996784 ! regulation of synaptogenesis GO:0051963 10 7 1,000 6,945E-04 0,01972132 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 1,000 6,945E-04 0,01948081 ! response to drug GO:0042493 108 69 3,000 7,06E-04 0,019563 ! eye development GO:0001654 111 70 3,000 7,454E-04 0,02041055 ! positive regulation of phosphorylation GO:0042327 102 70 3,000 7,454E-04 0,02017043 ! mammary gland development GO:0030879 57 31 2,000 7,698E-04 0,02058661 ! regulation of striated muscle tissue development GO:0016202 47 31 2,000 7,698E-04 0,02034998 ! mesoderm morphogenesis GO:0048332 49 31 2,000 7,698E-04 0,02011873 ! leukocyte chemotaxis GO:0030595 43 31 2,000 7,698E-04 0,01989268 GO:0060326|cell chemotaxis, ! positive regulation of phosphorus metabolic process GO:0010562 107 72 3,000 8,29E-04 0,02118518 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of synaptic transmission GO:0050804 109 72 3,000 8,29E-04 0,02095237 ! regulation of muscle development GO:0048634 48 32 2,000 8,458E-04 0,02114517 ! regulation of synaptic plasticity GO:0048167 52 32 2,000 8,458E-04 0,0209178 ! negative regulation of transport GO:0051051 116 73 3,000 8,731E-04 0,02136425 ! mitochondrion organization GO:0007005 104 73 3,000 8,731E-04 0,02113937 ! succinate metabolic process GO:0006105 14 8 1,000 9,225E-04 0,02210205 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 9,225E-04 0,0218742 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 9,225E-04 0,02165099 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 9,225E-04 0,02143229 ! regulation of telomere maintenance GO:0032204 10 8 1,000 9,225E-04 0,02121797 ! regulation of embryonic development GO:0045995 16 8 1,000 9,225E-04 0,02100789 ! keratinocyte proliferation GO:0043616 12 8 1,000 9,225E-04 0,02080193 ! middle ear morphogenesis GO:0042474 9 8 1,000 9,225E-04 0,02059997 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 9,225E-04 0,02040189 ! cytokinesis GO:0000910 52 33 2,000 9,265E-04 0,02029396 ! dorsal/ventral pattern formation GO:0009953 44 34 2,000 1,012E-03 0,02195493 ! gland development GO:0048732 148 77 3,000 1,066E-03 0,02292393 ! regulation of transmission of nerve impulse GO:0051969 116 77 3,000 1,066E-03 0,02271167 ! regulation of action potential in neuron GO:0019228 54 35 2,000 1,102E-03 0,02325384 ! positive regulation of protein modification process GO:0031401 107 78 3,000 1,119E-03 0,02339978 ! regulation of developmental growth GO:0048638 13 9 1,000 1,182E-03 0,02448331 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 1,000 1,182E-03 0,02426471 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 1,182E-03 0,02404998 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,182E-03 0,02383901 GO:0006600|creatine metabolic process, ! indolalkylamine metabolic process GO:0006586 14 9 1,000 1,182E-03 0,02363172 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! motor axon guidance GO:0008045 14 9 1,000 1,182E-03 0,023428 ! response to amine stimulus GO:0014075 13 9 1,000 1,182E-03 0,02322776 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 1,000 1,182E-03 0,02303091 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 1,182E-03 0,02283737 ! regulation of synapse organization GO:0050807 12 9 1,000 1,182E-03 0,02264706 ! forebrain development GO:0030900 131 80 3,000 1,23E-03 0,02337759 ! regulation of neurological system process GO:0031644 122 81 3,000 1,288E-03 0,02428226 ! negative regulation of muscle development GO:0048635 12 10 1,000 1,471E-03 0,02751336 ! hippocampus development GO:0021766 19 10 1,000 1,471E-03 0,02729148 ! melanocyte differentiation GO:0030318 15 10 1,000 1,471E-03 0,02707314 GO:0050931|pigment cell differentiation, ! DNA methylation GO:0006306 15 10 1,000 1,471E-03 0,02685828 GO:0006305|DNA alkylation, ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 1,471E-03 0,0266468 ! regulation of synapse structure and activity GO:0050803 13 10 1,000 1,471E-03 0,02643862 ! JNK cascade GO:0007254 54 39 2,000 1,513E-03 0,02697652 ! regulation of membrane potential GO:0042391 128 85 3,000 1,54E-03 0,02724462 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 1,608E-03 0,02822985 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 2,000 1,629E-03 0,02838099 ! positive regulation of response to external stimulus GO:0032103 65 40 2,000 1,629E-03 0,0281676 ! epidermal cell differentiation GO:0009913 53 40 2,000 1,629E-03 0,02795739 ! interphase GO:0051325 159 88 3,000 1,75E-03 0,02981494 ! epithelial cell differentiation GO:0030855 55 41 2,000 1,75E-03 0,02959585 ! ER-associated protein catabolic process GO:0030433 14 11 1,000 1,792E-03 0,03007632 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! detection of mechanical stimulus GO:0050982 15 11 1,000 1,792E-03 0,02985837 ! plasma membrane organization GO:0007009 18 11 1,000 1,792E-03 0,02964356 ! stem cell development GO:0048864 29 11 1,000 1,792E-03 0,02943182 GO:0019827|stem cell maintenance, ! positive regulation of T cell mediated immunity GO:0002711 18 11 1,000 1,792E-03 0,02922309 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 1,792E-03 0,02901729 GO:0042130|negative regulation of T cell proliferation, ! protein modification by small protein conjugation GO:0032446 140 90 3,000 1,901E-03 0,03056971 ! leukocyte migration GO:0050900 60 43 2,000 2,009E-03 0,03208764 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 1,000 2,142E-03 0,03397078 ! positive regulation of cell growth GO:0030307 16 12 1,000 2,142E-03 0,0337381 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 2,142E-03 0,03350859 ! cell-cell junction assembly GO:0007043 18 12 1,000 2,142E-03 0,03328218 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 2,143E-03 0,03308114 ! regulation of action potential GO:0001508 71 44 2,000 2,147E-03 0,03291904 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 2,147E-03 0,03270103 ! regulation of inflammatory response GO:0050727 60 44 2,000 2,147E-03 0,03248589 ! positive regulation of defense response GO:0031349 59 45 2,000 2,291E-03 0,03443341 ! protein modification by small protein conjugation or removal GO:0070647 148 96 3,000 2,406E-03 0,03593511 ! regulation of exocytosis GO:0017157 17 13 1,000 2,521E-03 0,03741452 ! regulation of cytokine production during immune response GO:0002718 18 13 1,000 2,521E-03 0,03717469 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 2,521E-03 0,0369379 ! cellular pigmentation GO:0033059 24 13 1,000 2,521E-03 0,03670412 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 3,000 2,691E-03 0,03891939 ! regulation of muscle contraction GO:0006937 69 48 2,000 2,757E-03 0,03963028 ! gastrulation GO:0007369 73 48 2,000 2,757E-03 0,03938413 ! regulation of angiogenesis GO:0045765 94 49 2,000 2,924E-03 0,04151854 ! cartilage development GO:0051216 70 49 2,000 2,924E-03 0,04126382 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 2,93E-03 0,04109825 ! startle response GO:0001964 21 14 1,000 2,93E-03 0,04084917 ! negative regulation of caspase activity GO:0043154 20 14 1,000 2,93E-03 0,04060309 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 2,93E-03 0,04035996 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 1,000 2,93E-03 0,04011972 ! limbic system development GO:0021761 25 14 1,000 2,93E-03 0,03988233 ! positive regulation of growth GO:0045927 67 50 2,000 3,098E-03 0,04191336 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 3,278E-03 0,04408663 ! regulation of protein catabolic process GO:0042176 77 51 2,000 3,278E-03 0,04383031 ! positive regulation of cell size GO:0045793 20 15 1,000 3,368E-03 0,04478352 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 3,368E-03 0,04452614 ! skin development GO:0043588 25 15 1,000 3,368E-03 0,04427171 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 3,368E-03 0,04402016 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 3,368E-03 0,04377146 ! regulation of neurotransmitter secretion GO:0046928 26 15 1,000 3,368E-03 0,04352556 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 1,000 3,368E-03 0,0432824 ! regulation of survival gene product expression GO:0045884 20 15 1,000 3,368E-03 0,04304194 ! regulation of T cell mediated immunity GO:0002709 26 15 1,000 3,368E-03 0,04280414 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 3,368E-03 0,04256895 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 3,368E-03 0,04233633 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! establishment of organelle localization GO:0051656 85 52 2,000 3,464E-03 0,04329777 ! DNA replication initiation GO:0006270 25 16 1,000 3,835E-03 0,04767981 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 3,835E-03 0,04742347 ! cytokine-mediated signaling pathway GO:0019221 76 54 2,000 3,855E-03 0,04741534 ! mesoderm development GO:0007498 76 55 2,000 4,06E-03 0,04967485 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 4,272E-03 0,05198999 ! forelimb morphogenesis GO:0035136 19 17 1,000 4,33E-03 0,05241565 ! memory GO:0007613 25 17 1,000 4,33E-03 0,05214122 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 4,33E-03 0,05186966 ! neuromuscular junction development GO:0007528 23 17 1,000 4,33E-03 0,0516009 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 4,33E-03 0,05133492 ! stem cell differentiation GO:0048863 36 17 1,000 4,33E-03 0,05107166 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 4,33E-03 0,05081109 ! cell-cell junction organization GO:0045216 25 17 1,000 4,33E-03 0,05055317 ! proximal/distal pattern formation GO:0009954 25 17 1,000 4,33E-03 0,05029785 ! positive regulation of synaptic transmission GO:0050806 24 17 1,000 4,33E-03 0,0500451 ! camera-type eye development GO:0043010 88 57 2,000 4,491E-03 0,05164261 ! protein amino acid ADP-ribosylation GO:0006471 27 18 1,000 4,853E-03 0,05552934 ! axis specification GO:0009798 26 18 1,000 4,853E-03 0,05525444 ! response to retinoic acid GO:0032526 25 18 1,000 4,853E-03 0,05498225 ! visual learning GO:0008542 35 18 1,000 4,853E-03 0,05471273 ! somitogenesis GO:0001756 24 18 1,000 4,853E-03 0,05444584 ! synaptic vesicle transport GO:0048489 33 18 1,000 4,853E-03 0,05418154 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 1,000 4,853E-03 0,05391979 ! activation of JUN kinase activity GO:0007257 23 18 1,000 4,853E-03 0,05366056 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 1,000 4,853E-03 0,05340381 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 4,853E-03 0,05314951 ! negative regulation of T cell activation GO:0050868 25 18 1,000 4,853E-03 0,05289762 ! activation of MAPK activity GO:0000187 84 59 2,000 4,948E-03 0,05367647 ! embryonic limb morphogenesis GO:0030326 86 60 2,000 5,186E-03 0,05600071 GO:0035113|embryonic appendage morphogenesis, ! regulation of heart contraction GO:0008016 91 60 2,000 5,186E-03 0,05573903 ! regulation of homeostatic process GO:0032844 105 60 2,000 5,186E-03 0,05547978 ! regulation of postsynaptic membrane potential GO:0060078 30 19 1,000 5,403E-03 0,05753361 ! response to alkaloid GO:0043279 32 19 1,000 5,403E-03 0,05726848 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 5,403E-03 0,05700578 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 5,403E-03 0,05674548 ! response to vitamin A GO:0033189 26 19 1,000 5,403E-03 0,05648755 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 5,403E-03 0,05623195 ! apoptotic nuclear changes GO:0030262 24 19 1,000 5,403E-03 0,05597865 ! sex determination GO:0007530 29 19 1,000 5,403E-03 0,05572763 ! plasma membrane fusion GO:0045026 23 19 1,000 5,403E-03 0,05547884 ! regulation of interleukin-2 production GO:0032663 31 19 1,000 5,403E-03 0,05523227 ! positive regulation of neurological system process GO:0031646 28 19 1,000 5,403E-03 0,05498788 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 5,403E-03 0,05474564 ! urogenital system development GO:0001655 101 61 2,000 5,432E-03 0,05479205 ! organelle localization GO:0051640 96 62 2,000 5,684E-03 0,05708664 ! response to vitamin GO:0033273 29 20 1,000 5,981E-03 0,05980782 ! regulation of neurotransmitter transport GO:0051588 35 20 1,000 5,981E-03 0,05954891 ! response to ethanol GO:0045471 37 20 1,000 5,981E-03 0,05929223 ! pallium development GO:0021543 38 20 1,000 5,981E-03 0,05903776 ! DNA modification GO:0006304 28 20 1,000 5,981E-03 0,05878546 ! appendage morphogenesis GO:0035107 93 64 2,000 6,209E-03 0,06077132 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 90 65 2,000 6,482E-03 0,0631765 ! regulation of caspase activity GO:0043281 97 65 2,000 6,482E-03 0,06290993 ! appendage development GO:0048736 94 65 2,000 6,482E-03 0,0626456 GO:0060173|limb development, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 6,585E-03 0,06337343 ! gluconeogenesis GO:0006094 25 21 1,000 6,585E-03 0,06310938 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 6,585E-03 0,06284751 ! visual behavior GO:0007632 39 21 1,000 6,585E-03 0,06258781 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 6,585E-03 0,06233025 ! positive regulation of adaptive immune response GO:0002821 31 21 1,000 6,585E-03 0,0620748 ! axon guidance GO:0007411 99 66 2,000 6,763E-03 0,06348698 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 7,05E-03 0,06591598 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 7,216E-03 0,06719783 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 7,216E-03 0,06692687 ! glutamate signaling pathway GO:0007215 34 22 1,000 7,216E-03 0,06665809 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 7,216E-03 0,06639146 ! vasculogenesis GO:0001570 33 22 1,000 7,216E-03 0,06612695 ! regulation of tumor necrosis factor production GO:0032680 28 22 1,000 7,216E-03 0,06586454 ! membrane depolarization GO:0051899 35 22 1,000 7,216E-03 0,0656042 ! positive regulation of JUN kinase activity GO:0043507 28 22 1,000 7,216E-03 0,06534592 ! activation of protein kinase activity GO:0032147 102 69 2,000 7,646E-03 0,06896811 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 7,874E-03 0,07074177 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 7,874E-03 0,07046651 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 7,874E-03 0,07019338 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 7,874E-03 0,06992236 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 7,874E-03 0,06965343 ! vesicle targeting GO:0006903 32 23 1,000 7,874E-03 0,06938656 ! cellular response to oxidative stress GO:0034599 33 23 1,000 7,874E-03 0,06912172 ! cell fate determination GO:0001709 45 23 1,000 7,874E-03 0,0688589 ! negative regulation of catabolic process GO:0009895 34 23 1,000 7,874E-03 0,06859808 ! regulation of catabolic process GO:0009894 106 70 2,000 7,955E-03 0,06904744 ! pyruvate metabolic process GO:0006090 29 24 1,000 8,557E-03 0,07399096 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 1,000 8,557E-03 0,07371384 GO:0002708|positive regulation of lymphocyte mediated immunity, ! neurotransmitter secretion GO:0007269 32 24 1,000 8,557E-03 0,07343878 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 8,557E-03 0,07316578 ! regulation of peptidase activity GO:0052547 106 72 2,000 8,595E-03 0,07321961 ! male gonad development GO:0008584 33 25 1,000 9,266E-03 0,07864294 ! iron ion homeostasis GO:0055072 39 25 1,000 9,266E-03 0,07835381 ! positive regulation of nuclear division GO:0051785 39 25 1,000 9,266E-03 0,0780668 GO:0045840|positive regulation of mitosis, ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 9,266E-03 0,07778189 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,01000048 0,08364034 ! post-embryonic development GO:0009791 42 26 1,000 0,01000048 0,0833373 ! spermatid differentiation GO:0048515 36 26 1,000 0,01000048 0,08303644 ! sex differentiation GO:0007548 105 77 2,000 0,0103243 0,08541689 ! GPI anchor biosynthetic process GO:0006506 37 27 1,000 0,01075976 0,08870051 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 0,01075976 0,08838372 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 0,01075976 0,08806919 ! negative regulation of protein transport GO:0051224 49 27 1,000 0,01075976 0,08775689 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,01154373 0,09381827 ! cell junction assembly GO:0034329 56 28 1,000 0,01154373 0,09348792 ! GPI anchor metabolic process GO:0006505 40 28 1,000 0,01154373 0,09315989 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 0,01154373 0,09283416 ! placenta development GO:0001890 37 28 1,000 0,01154373 0,0925107 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01235207 0,09864502 ! telencephalon development GO:0021537 52 29 1,000 0,01235207 0,09830369 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,01235207 0,09796471 ! biogenic amine metabolic process GO:0006576 121 83 2,000 0,01264716 0,09996038 ! regulation of cell adhesion GO:0030155 159 83 2,000 0,01264716 0,09961805 ! regulation of defense response GO:0031347 117 84 2,000 0,01306098 0,10252648 ! spindle organization GO:0007051 37 30 1,000 0,01318449 0,10314397 ! hindbrain development GO:0030902 45 30 1,000 0,01318449 0,10279433 ! negative regulation of cell activation GO:0050866 44 30 1,000 0,01318449 0,10244705 ! positive regulation of immune effector process GO:0002699 40 30 1,000 0,01318449 0,10210211 ! establishment of vesicle localization GO:0051650 45 30 1,000 0,01318449 0,10175949 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 0,01348248 0,10371142 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 0,01404068 0,1076452 ! odontogenesis GO:0042476 50 31 1,000 0,01404068 0,10728758 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,01404068 0,10693232 ! segmentation GO:0035282 41 31 1,000 0,01404068 0,10657941 ! metanephros development GO:0001656 58 31 1,000 0,01404068 0,10622882 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,01404068 0,10588053 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,01492034 0,11214632 ! meiosis I GO:0007127 52 32 1,000 0,01492034 0,11178102 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01492034 0,1114181 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,01492034 0,11105752 ! vesicle localization GO:0051648 47 32 1,000 0,01492034 0,11069927 ! reproductive developmental process GO:0003006 127 89 2,000 0,01524567 0,11274935 ! regulation of T cell activation GO:0050863 128 89 2,000 0,01524567 0,11238797 ! phosphoinositide biosynthetic process GO:0046489 47 33 1,000 0,01582317 0,11627247 ! ear morphogenesis GO:0042471 42 33 1,000 0,01582317 0,11590218 ! cell junction organization GO:0034330 63 33 1,000 0,01582317 0,11553424 ! nucleus organization GO:0006997 49 33 1,000 0,01582317 0,11516862 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,01582317 0,11480531 ! regulation of proteolysis GO:0030162 50 33 1,000 0,01582317 0,11444429 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,01582317 0,11408553 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,01582317 0,11372901 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,01674888 0,12000752 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,01674888 0,11963482 ! neuron migration GO:0001764 46 34 1,000 0,01674888 0,11926444 ! response to oxidative stress GO:0006979 141 94 2,000 0,01762446 0,12511188 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,01769717 0,1252415 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,01769717 0,12485733 ! maintenance of protein location GO:0045185 65 35 1,000 0,01769717 0,1244755 ! regulation of response to external stimulus GO:0032101 139 96 2,000 0,01863066 0,13064182 ! response to light stimulus GO:0009416 153 96 2,000 0,01863066 0,13024474 ! response to reactive oxygen species GO:0000302 55 36 1,000 0,01866776 0,13010862 ! cellular amide metabolic process GO:0043603 52 36 1,000 0,01866776 0,12971554 ! negative regulation of binding GO:0051100 58 36 1,000 0,01866776 0,12932483 ! neural tube development GO:0021915 50 36 1,000 0,01866776 0,12893647 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 2,000 0,01914552 0,13184039 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,01966036 0,13498155 ! learning GO:0007612 67 37 1,000 0,01966036 0,13457982 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,02067468 0,14110315 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,02067468 0,14068569 ! maintenance of location in cell GO:0051651 69 38 1,000 0,02067468 0,14027069 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,02171044 0,14686477 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,02171044 0,14643408 ! male sex differentiation GO:0046661 53 39 1,000 0,02171044 0,14600591 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 1,000 0,02171044 0,14558024 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 1,000 0,02171044 0,14515704 ! cell growth GO:0016049 61 39 1,000 0,02171044 0,14473629 ! synapse organization GO:0050808 55 39 1,000 0,02171044 0,14431798 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,02276737 0,15090765 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,02276737 0,15047401 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,02276737 0,15004285 ! protein amino acid lipidation GO:0006497 62 41 1,000 0,02384518 0,15669693 ! regulation of leukocyte mediated immunity GO:0002703 62 41 1,000 0,02384518 0,1562505 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,02384518 0,1558066 ! biopolymer methylation GO:0043414 62 41 1,000 0,02384518 0,15536523 ! regulation of JNK cascade GO:0046328 58 41 1,000 0,02384518 0,15492634 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,02494361 0,16160648 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,02494361 0,16115253 ! cellular component disassembly GO:0022411 64 42 1,000 0,02494361 0,16070112 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,02494361 0,16025224 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 1,000 0,02494361 0,15980585 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,02494361 0,15936195 ! regulation of cell shape GO:0008360 78 42 1,000 0,02494361 0,1589205 ! neuromuscular process GO:0050905 79 43 1,000 0,02606237 0,16558966 ! activation of caspase activity GO:0006919 65 43 1,000 0,02606237 0,16513349 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 0,02606237 0,16467982 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,02606237 0,16422865 ! methylation GO:0032259 64 43 1,000 0,02606237 0,16377993 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,0272012 0,17047076 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,0272012 0,17000753 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,0272012 0,1695468 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,02835984 0,17629089 ! lipoprotein biosynthetic process GO:0042158 67 45 1,000 0,02835984 0,17581571 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,02835984 0,17534309 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02883768 0,17781949 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02883768 0,17734404 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02883768 0,17687112 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02883768 0,17640072 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02883768 0,17593281 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02883768 0,17546738 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02883768 0,1750044 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02883768 0,17454387 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02883768 0,17408575 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02883768 0,17363002 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02883768 0,17317668 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02883768 0,1727257 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02883768 0,17227706 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02883768 0,17183075 ! tongue development GO:0043586 6 5 0,000 0,02883768 0,17138674 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02883768 0,17094502 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02883768 0,17050558 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02883768 0,17006838 ! cobalt ion transport GO:0006824 9 5 0,000 0,02883768 0,16963343 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02883768 0,16920069 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02883768 0,16877015 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02883768 0,1683418 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02883768 0,16791562 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02883768 0,16749159 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02883768 0,1670697 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02883768 0,16664992 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02883768 0,16623225 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02883768 0,16581667 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02883768 0,16540317 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02883768 0,16499172 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02883768 0,16458231 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02883768 0,16417492 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02883768 0,16376955 ! malate metabolic process GO:0006108 7 5 0,000 0,02883768 0,16336618 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02883768 0,16296479 ! behavioral response to pain GO:0048266 7 5 0,000 0,02883768 0,16256537 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02883768 0,1621679 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02883768 0,16177236 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02883768 0,16137876 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02883768 0,16098706 ! mating behavior GO:0007617 6 5 0,000 0,02883768 0,16059726 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02883768 0,16020935 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02883768 0,1598233 ! rhythmic behavior GO:0007622 12 5 0,000 0,02883768 0,15943911 ! copulation GO:0007620 7 5 0,000 0,02883768 0,15905676 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02883768 0,15867624 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02883768 0,15829754 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02883768 0,15792064 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02883768 0,15754553 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02883768 0,1571722 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02883768 0,15680064 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02883768 0,15643082 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02883768 0,15606275 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02883768 0,15569641 ! response to protozoan GO:0001562 9 5 0,000 0,02883768 0,15533178 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02883768 0,15496885 ! lymph vessel development GO:0001945 7 5 0,000 0,02883768 0,15460762 ! endochondral ossification GO:0001958 12 5 0,000 0,02883768 0,15424807 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02883768 0,15389018 ! parathyroid gland development GO:0060017 8 5 0,000 0,02883768 0,15353396 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02883768 0,15317938 ! anagen GO:0042640 6 5 0,000 0,02883768 0,15282643 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02883768 0,1524751 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02883768 0,15212539 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02883768 0,15177728 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02883768 0,15143075 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02883768 0,15108581 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02883768 0,15074243 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02883768 0,15040061 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02883768 0,15006034 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02883768 0,1497216 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02883768 0,14938439 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02883768 0,1490487 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02883768 0,14871451 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02883768 0,14838181 ! ovulation GO:0030728 6 5 0,000 0,02883768 0,1480506 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02883768 0,14772087 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02883768 0,1473926 GO:0030033|microvillus assembly, ! response to pH GO:0009268 9 5 0,000 0,02883768 0,14706579 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02883768 0,14674042 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02883768 0,14641649 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02883768 0,14609399 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02883768 0,1457729 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02883768 0,14545322 ! polyol catabolic process GO:0046174 7 5 0,000 0,02883768 0,14513494 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02883768 0,14481806 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02883768 0,14450255 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02883768 0,14418841 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02883768 0,14387564 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02883768 0,14356422 ! urea metabolic process GO:0019627 6 5 0,000 0,02883768 0,14325415 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02883768 0,14294541 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02883768 0,142638 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02883768 0,14233191 ! neutrophil activation GO:0042119 5 5 0,000 0,02883768 0,14202713 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02883768 0,14172365 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02883768 0,14142147 ! response to food GO:0032094 5 5 0,000 0,02883768 0,14112057 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02883768 0,14082095 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02883768 0,1405226 ! forebrain neuron development GO:0021884 7 5 0,000 0,02883768 0,14022552 ! melanosome organization GO:0032438 7 5 0,000 0,02883768 0,13992968 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02883768 0,13963509 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02883768 0,13934174 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02883768 0,13904962 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02883768 0,13875872 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02883768 0,13846904 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02883768 0,13818056 ! nucleoside transport GO:0015858 6 5 0,000 0,02883768 0,13789328 ! nucleoside salvage GO:0043174 7 5 0,000 0,02883768 0,1376072 GO:0006166|purine ribonucleoside salvage, ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02883768 0,1373223 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02883768 0,13703857 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02883768 0,13675602 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02883768 0,13647463 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02883768 0,13619439 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02883768 0,13591531 ! depyrimidination GO:0045008 8 5 0,000 0,02883768 0,13563736 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02883768 0,13536055 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02883768 0,13508487 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02883768 0,1348103 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02883768 0,13453685 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02883768 0,13426451 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02883768 0,13399327 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02883768 0,13372312 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02883768 0,13345406 ! monocyte differentiation GO:0030224 8 5 0,000 0,02883768 0,13318608 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02883768 0,13291918 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02883768 0,13265334 ! centrosome duplication GO:0051298 5 5 0,000 0,02883768 0,13238856 ! response to UV-C GO:0010225 6 5 0,000 0,02883768 0,13212484 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02883768 0,13186217 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02883768 0,13160053 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02883768 0,13133994 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02883768 0,13108037 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02883768 0,13082183 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02883768 0,13056431 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02883768 0,1303078 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02883768 0,13005229 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02883768 0,12979779 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02883768 0,12954428 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02883768 0,12929175 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02883768 0,12904021 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02883768 0,12878965 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02883768 0,12854006 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02883768 0,12829143 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02883768 0,12804376 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02883768 0,12779705 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02883768 0,12755129 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02883768 0,12730647 ! histone demethylation GO:0016577 9 5 0,000 0,02883768 0,12706259 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02883768 0,12681964 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02883768 0,12657761 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02883768 0,12633651 ! enteric nervous system development GO:0048484 8 5 0,000 0,02883768 0,12609633 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02883768 0,12585706 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02883768 0,12561869 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02883768 0,12538123 ! transcription termination GO:0006353 8 5 0,000 0,02883768 0,12514466 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02883768 0,12490898 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02883768 0,12467419 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02883768 0,12444028 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02883768 0,12420725 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02883768 0,12397508 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02883768 0,12374379 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02883768 0,12351335 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02883768 0,12328377 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02883768 0,12305505 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02883768 0,12282717 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02883768 0,12260013 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02883768 0,12237393 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02883768 0,12214856 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02883768 0,12192402 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02883768 0,12170031 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02883768 0,12147742 ! glial cell migration GO:0008347 10 5 0,000 0,02883768 0,12125534 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02883768 0,12103407 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02883768 0,12081361 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02883768 0,12059394 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02883768 0,12037508 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02883768 0,12015701 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02883768 0,11993973 ! neural plate development GO:0001840 6 5 0,000 0,02883768 0,11972323 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02883768 0,11950751 ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02883768 0,11929257 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02883768 0,1190784 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02883768 0,118865 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02883768 0,11865236 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02883768 0,11844048 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02883768 0,11822936 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02883768 0,11801898 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02883768 0,11780936 ! spindle assembly GO:0051225 5 5 0,000 0,02883768 0,11760048 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02883768 0,11739234 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02883768 0,11718493 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02883768 0,11697825 ! organ regeneration GO:0031100 7 5 0,000 0,02883768 0,11677231 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02883768 0,11656708 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02883768 0,11636258 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02883768 0,11615879 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02883768 0,11595572 GO:0055081|anion homeostasis, ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,02953801 0,11856444 ! response to UV GO:0009411 75 46 1,000 0,02953801 0,11835788 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,03073545 0,12294182 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,03073545 0,12272838 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,03195191 0,12736465 GO:0010952|positive regulation of peptidase activity, ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,03195191 0,1271443 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,03195191 0,1269247 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,03195191 0,12670587 ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,03195191 0,12648778 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,03318713 0,13115189 ! germ cell development GO:0007281 68 49 1,000 0,03318713 0,13092693 ! maintenance of location GO:0051235 84 49 1,000 0,03318713 0,13070274 ! regulation of actin filament length GO:0030832 72 50 1,000 0,03444085 0,13540845 ! ear development GO:0043583 72 50 1,000 0,03444085 0,13517738 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,03444085 0,1349471 ! membrane fusion GO:0006944 80 50 1,000 0,03444085 0,13471759 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,03444085 0,13448887 ! tRNA transcription GO:0009304 11 6 0,000 0,03450562 0,13451344 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03450562 0,13428583 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03450562 0,134059 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03450562 0,13383293 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03450562 0,13360762 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03450562 0,13338307 ! regulation of helicase activity GO:0051095 11 6 0,000 0,03450562 0,13315927 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03450562 0,13293623 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03450562 0,13271393 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03450562 0,13249237 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03450562 0,13227155 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03450562 0,13205146 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03450562 0,13183211 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03450562 0,13161348 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,03450562 0,13139558 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03450562 0,13117839 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03450562 0,13096193 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03450562 0,13074617 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03450562 0,13053113 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03450562 0,13031679 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,03450562 0,13010316 ! neuron adhesion GO:0007158 9 6 0,000 0,03450562 0,12989022 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,03450562 0,12967799 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03450562 0,12946644 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03450562 0,12925558 ! signal peptide processing GO:0006465 8 6 0,000 0,03450562 0,12904541 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03450562 0,12883592 ! mRNA stabilization GO:0048255 15 6 0,000 0,03450562 0,12862711 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03450562 0,12841898 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03450562 0,12821151 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03450562 0,12800472 ! opsonization GO:0008228 8 6 0,000 0,03450562 0,12779859 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03450562 0,12759313 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03450562 0,12738833 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03450562 0,12718418 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03450562 0,12698068 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03450562 0,12677784 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03450562 0,12657564 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03450562 0,12637409 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03450562 0,12617318 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03450562 0,1259729 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03450562 0,12577326 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03450562 0,12557425 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03450562 0,12537587 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03450562 0,12517812 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03450562 0,12498099 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03450562 0,12478448 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03450562 0,12458858 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03450562 0,1243933 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03450562 0,12419863 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03450562 0,12400457 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03450562 0,12381112 ! thymic T cell selection GO:0045061 12 6 0,000 0,03450562 0,12361827 ! protein lipoylation GO:0009249 10 6 0,000 0,03450562 0,12342601 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03450562 0,12323436 ! pigment granule organization GO:0048753 11 6 0,000 0,03450562 0,1230433 ! drug transport GO:0015893 6 6 0,000 0,03450562 0,12285283 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03450562 0,12266295 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,03450562 0,12247365 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03450562 0,12228494 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03450562 0,12209681 ! histidine metabolic process GO:0006547 6 6 0,000 0,03450562 0,12190926 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03450562 0,12172228 ! glycine catabolic process GO:0006546 9 6 0,000 0,03450562 0,12153588 ! adenohypophysis development GO:0021984 10 6 0,000 0,03450562 0,12135004 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03450562 0,12116477 ! hyperosmotic response GO:0006972 8 6 0,000 0,03450562 0,12098007 ! microtubule nucleation GO:0007020 10 6 0,000 0,03450562 0,12079593 ! ER overload response GO:0006983 7 6 0,000 0,03450562 0,12061235 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03450562 0,12042933 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03450562 0,12024686 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03450562 0,12006494 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03450562 0,11988358 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03450562 0,11970276 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,03450562 0,11952248 ! response to dietary excess GO:0002021 7 6 0,000 0,03450562 0,11934275 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03450562 0,11916355 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03450562 0,1189849 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03450562 0,11880678 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03450562 0,11862919 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03450562 0,11845213 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03450562 0,1182756 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03450562 0,11809959 ! neuron apoptosis GO:0051402 8 6 0,000 0,03450562 0,11792411 ! organic alcohol transport GO:0015850 9 6 0,000 0,03450562 0,11774915 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03450562 0,11757471 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03450562 0,11740078 ! male sex determination GO:0030238 9 6 0,000 0,03450562 0,11722737 ! carnitine transport GO:0015879 8 6 0,000 0,03450562 0,11705447 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03450562 0,11688207 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03450562 0,11671019 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03450562 0,11653881 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03450562 0,11636793 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03450562 0,11619755 ! parturition GO:0007567 12 6 0,000 0,03450562 0,11602767 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03450562 0,11585829 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03450562 0,1156894 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03450562 0,115521 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03450562 0,11535309 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03450562 0,11518567 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03450562 0,11501874 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03450562 0,11485228 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03450562 0,11468631 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03450562 0,11452082 ! macrophage differentiation GO:0030225 10 6 0,000 0,03450562 0,1143558 ! astrocyte development GO:0014002 14 6 0,000 0,03450562 0,11419126 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03450562 0,11402719 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03450562 0,1138636 ! interaction with symbiont GO:0051702 8 6 0,000 0,03450562 0,11370047 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03450562 0,11353781 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03450562 0,11337561 ! eating behavior GO:0042755 6 6 0,000 0,03450562 0,11321388 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03450562 0,1130526 ! response to copper ion GO:0046688 9 6 0,000 0,03450562 0,11289179 ! DNA topological change GO:0006265 8 6 0,000 0,03450562 0,11273143 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03450562 0,11257153 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03450562 0,11241208 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03450562 0,11225308 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03450562 0,11209453 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03450562 0,11193643 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03450562 0,11177877 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03450562 0,11162156 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03450562 0,11146479 ! gas homeostasis GO:0033483 11 6 0,000 0,03450562 0,11130845 ! hair follicle maturation GO:0048820 7 6 0,000 0,03450562 0,11115256 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03450562 0,1109971 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03450562 0,11084208 ! Schwann cell development GO:0014044 14 6 0,000 0,03450562 0,11068749 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03450562 0,11053333 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03450562 0,11037959 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03450562 0,11022629 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03450562 0,11007341 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03450562 0,10992095 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03450562 0,10976892 ! histone ubiquitination GO:0016574 7 6 0,000 0,03450562 0,1096173 ! regulation of meiosis GO:0040020 10 6 0,000 0,03450562 0,10946611 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03450562 0,10931533 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03450562 0,10916496 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03450562 0,10901501 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03450562 0,10886547 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03450562 0,10871634 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03450562 0,10856762 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03450562 0,1084193 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03450562 0,10827139 ! receptor internalization GO:0031623 9 6 0,000 0,03450562 0,10812388 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03450562 0,10797677 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03450562 0,10783006 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03450562 0,10768375 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03450562 0,10753784 ! protein deubiquitination GO:0016579 8 6 0,000 0,03450562 0,10739232 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03450562 0,1072472 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,03450562 0,10710247 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03450562 0,10695812 ! axonal fasciculation GO:0007413 9 6 0,000 0,03450562 0,10681417 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03450562 0,1066706 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03450562 0,10652742 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03450562 0,10638462 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03450562 0,10624221 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03450562 0,10610017 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03450562 0,10595851 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03450562 0,10581724 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03450562 0,10567633 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03450562 0,10553581 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03450562 0,10539565 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03450562 0,10525587 ! adult feeding behavior GO:0008343 6 6 0,000 0,03450562 0,10511646 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03450562 0,10497742 ! blastocyst growth GO:0001832 15 6 0,000 0,03450562 0,10483874 ! pigment granule transport GO:0051904 12 6 0,000 0,03450562 0,10470043 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03450562 0,10456249 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03450562 0,1044249 ! catecholamine transport GO:0051937 7 6 0,000 0,03450562 0,10428768 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03450562 0,10415082 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03450562 0,10401432 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03450562 0,10387818 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,03450562 0,10374239 ! protein prenylation GO:0018342 10 6 0,000 0,03450562 0,10360695 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03450562 0,10347187 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,03450562 0,10333715 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03450562 0,10320277 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03450562 0,10306874 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03450562 0,10293505 ! positive regulation of secretion GO:0051047 71 51 1,000 0,03571281 0,10639827 ! muscle fiber development GO:0048747 74 51 1,000 0,03571281 0,10626062 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,03571281 0,10612333 ! regulation of cellular component size GO:0032535 74 52 1,000 0,03700277 0,10981467 ! glycerophospholipid biosynthetic process GO:0046474 75 53 1,000 0,03831048 0,11354909 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,03831048 0,11340295 ! kidney development GO:0001822 90 53 1,000 0,03831048 0,11325719 ! single fertilization GO:0007338 59 53 1,000 0,03831048 0,1131118 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,03831048 0,11296679 ! amino acid transport GO:0006865 84 54 1,000 0,03963568 0,1167248 ! regulation of mitosis GO:0007088 84 54 1,000 0,03963568 0,11657554 GO:0051783|regulation of nuclear division, ! DNA catabolic process GO:0006308 67 54 1,000 0,03963568 0,11642666 ! detection of external stimulus GO:0009581 66 54 1,000 0,03963568 0,11627815 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,0401408 0,11760999 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0401408 0,11746036 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0401408 0,11731111 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0401408 0,11716224 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0401408 0,11701374 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0401408 0,11686563 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0401408 0,11671788 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0401408 0,11657051 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0401408 0,11642351 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0401408 0,11627688 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0401408 0,11613062 ! reproductive behavior GO:0019098 12 7 0,000 0,0401408 0,11598473 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0401408 0,1158392 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,0401408 0,11569404 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0401408 0,11554924 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0401408 0,11540481 ! oligopeptide transport GO:0006857 11 7 0,000 0,0401408 0,11526073 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0401408 0,11511701 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0401408 0,11497365 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0401408 0,11483065 ! RNA methylation GO:0001510 11 7 0,000 0,0401408 0,11468801 ! pericardium development GO:0060039 8 7 0,000 0,0401408 0,11454571 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0401408 0,11440377 ! fibril organization GO:0043206 13 7 0,000 0,0401408 0,11426218 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0401408 0,11412094 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0401408 0,11398005 ! lipoprotein transport GO:0042953 9 7 0,000 0,0401408 0,11383951 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0401408 0,11369932 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0401408 0,11355946 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0401408 0,11341996 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0401408 0,11328079 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0401408 0,11314197 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0401408 0,11300348 ! chemosensory behavior GO:0007635 9 7 0,000 0,0401408 0,11286534 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0401408 0,11272753 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0401408 0,11259005 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0401408 0,11245292 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0401408 0,11231611 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0401408 0,11217964 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0401408 0,1120435 ! reflex GO:0060004 12 7 0,000 0,0401408 0,11190769 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0401408 0,11177221 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0401408 0,11163705 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0401408 0,11150223 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0401408 0,11136773 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0401408 0,11123355 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0401408 0,11109969 ! spinal cord patterning GO:0021511 7 7 0,000 0,0401408 0,11096616 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0401408 0,11083295 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0401408 0,11070005 ! adrenal gland development GO:0030325 17 7 0,000 0,0401408 0,11056748 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0401408 0,11043522 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0401408 0,11030328 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0401408 0,11017165 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0401408 0,11004034 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0401408 0,10990934 ! endosome organization GO:0007032 10 7 0,000 0,0401408 0,10977865 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0401408 0,10964827 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0401408 0,1095182 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0401408 0,10938844 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0401408 0,10925899 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0401408 0,10912984 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0401408 0,109001 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0401408 0,10887246 ! galactose metabolic process GO:0006012 10 7 0,000 0,0401408 0,10874422 ! vesicle fusion GO:0006906 15 7 0,000 0,0401408 0,10861629 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0401408 0,10848865 GO:0045851|pH reduction, ! organ growth GO:0035265 11 7 0,000 0,0401408 0,10836132 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0401408 0,10823428 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0401408 0,10810755 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0401408 0,1079811 ! retinol metabolic process GO:0042572 9 7 0,000 0,0401408 0,10785496 ! behavioral fear response GO:0001662 13 7 0,000 0,0401408 0,10772911 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0401408 0,10760355 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0401408 0,10747828 ! rRNA modification GO:0000154 12 7 0,000 0,0401408 0,10735331 ! protein heterooligomerization GO:0051291 10 7 0,000 0,0401408 0,10722862 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0401408 0,10710423 ! response to UV-B GO:0010224 11 7 0,000 0,0401408 0,10698012 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0401408 0,1068563 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0401408 0,10673277 ! intermediate filament organization GO:0045109 11 7 0,000 0,0401408 0,10660952 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0401408 0,10648656 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0401408 0,10636388 ! fibrinolysis GO:0042730 9 7 0,000 0,0401408 0,10624148 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0401408 0,10611936 ! B cell lineage commitment GO:0002326 17 7 0,000 0,0401408 0,10599752 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0401408 0,10587597 ! response to tropane GO:0014073 13 7 0,000 0,0401408 0,10575469 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0401408 0,10563369 ! melanosome localization GO:0032400 10 7 0,000 0,0401408 0,10551296 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0401408 0,10539252 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0401408 0,10527234 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0401408 0,10515244 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0401408 0,10503281 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0401408 0,10491346 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0401408 0,10479437 ! mast cell activation GO:0045576 9 7 0,000 0,0401408 0,10467556 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0401408 0,10455701 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0401408 0,10443874 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0401408 0,10432073 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0401408 0,10420298 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0401408 0,10408551 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0401408 0,10396829 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0401408 0,10385134 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0401408 0,10373466 ! T cell lineage commitment GO:0002360 12 7 0,000 0,0401408 0,10361823 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0401408 0,10350207 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0401408 0,10338616 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0401408 0,10327052 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0401408 0,10315513 ! response to tumor cell GO:0002347 12 7 0,000 0,0401408 0,10304 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0401408 0,10292513 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0401408 0,10281052 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0401408 0,10269616 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0401408 0,10258205 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0401408 0,1024682 ! diuresis GO:0030146 12 7 0,000 0,0401408 0,10235459 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0401408 0,10224124 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0401408 0,10212815 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0401408 0,1020153 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0401408 0,1019027 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0401408 0,10179035 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0401408 0,10167824 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0401408 0,10156639 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0401408 0,10145477 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0401408 0,10134341 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0401408 0,10123229 ! lymph node development GO:0048535 9 7 0,000 0,0401408 0,10112141 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0401408 0,10101077 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0401408 0,10090038 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0401408 0,10079022 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0401408 0,10068031 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0401408 0,10057064 ! ATP catabolic process GO:0006200 10 7 0,000 0,0401408 0,1004612 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0401408 0,100352 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0401408 0,10024304 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0401408 0,10013432 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0401408 0,10002583 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0401408 0,09991758 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0401408 0,09980956 ! muscle adaptation GO:0043500 12 7 0,000 0,0401408 0,09970178 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0401408 0,09959422 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0401408 0,0994869 ! retina homeostasis GO:0001895 9 7 0,000 0,0401408 0,09937981 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0401408 0,09927295 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0401408 0,09916632 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0401408 0,09905992 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0401408 0,09895375 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0401408 0,0988478 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0401408 0,09874208 ! exocytosis GO:0006887 74 55 1,000 0,04097815 0,10069417 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,04233763 0,10392374 ! gonad development GO:0008406 79 57 1,000 0,04371388 0,10718755 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,04510667 0,11048492 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,04510667 0,11036738 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04574341 0,11180643 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04574341 0,11168774 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,04574341 0,1115693 ! axon extension GO:0048675 11 8 0,000 0,04574341 0,11145111 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,04574341 0,11133318 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04574341 0,11121549 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04574341 0,11109805 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04574341 0,11098086 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04574341 0,11086391 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04574341 0,11074721 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,04574341 0,11063076 ! phosphate transport GO:0006817 10 8 0,000 0,04574341 0,11051455 ! N-glycan processing GO:0006491 12 8 0,000 0,04574341 0,11039858 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04574341 0,11028286 ! UTP metabolic process GO:0046051 8 8 0,000 0,04574341 0,11016738 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04574341 0,11005215 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04574341 0,10993715 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04574341 0,10982239 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,04574341 0,10970787 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04574341 0,10959359 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04574341 0,10947955 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04574341 0,10936575 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04574341 0,10925218 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04574341 0,10913885 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04574341 0,10902575 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04574341 0,10891289 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04574341 0,10880026 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04574341 0,10868786 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04574341 0,1085757 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04574341 0,10846376 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04574341 0,10835206 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04574341 0,10824059 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04574341 0,10812934 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04574341 0,10801833 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04574341 0,10790754 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04574341 0,10779698 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04574341 0,10768664 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04574341 0,10757653 ! melanin metabolic process GO:0006582 12 8 0,000 0,04574341 0,10746665 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04574341 0,10735699 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04574341 0,10724755 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,04574341 0,10713834 ! macrophage activation GO:0042116 12 8 0,000 0,04574341 0,10702935 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04574341 0,10692058 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04574341 0,10681203 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,04574341 0,1067037 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04574341 0,10659559 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04574341 0,1064877 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04574341 0,10638003 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04574341 0,10627258 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04574341 0,10616534 ! ruffle organization GO:0031529 11 8 0,000 0,04574341 0,10605832 ! osteoblast development GO:0002076 13 8 0,000 0,04574341 0,10595151 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04574341 0,10584492 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04574341 0,10573854 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04574341 0,10563238 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04574341 0,10552643 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04574341 0,10542069 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04574341 0,10531517 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04574341 0,10520985 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04574341 0,10510475 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04574341 0,10499985 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,04574341 0,10489517 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,04574341 0,10479069 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04574341 0,10468642 ! segment specification GO:0007379 10 8 0,000 0,04574341 0,10458236 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,04574341 0,1044785 ! cellular extravasation GO:0045123 11 8 0,000 0,04574341 0,10437485 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04574341 0,10427141 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04574341 0,10416817 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04574341 0,10406513 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04574341 0,1039623 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04574341 0,10385968 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04574341 0,10375725 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04574341 0,10365503 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04574341 0,103553 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04574341 0,10345118 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04574341 0,10334956 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04574341 0,10324814 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04574341 0,10314691 ! icosanoid secretion GO:0032309 12 8 0,000 0,04574341 0,10304589 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04574341 0,10294506 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04574341 0,10284443 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04574341 0,102744 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04574341 0,10264376 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04574341 0,10254371 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04574341 0,10244387 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04574341 0,10234421 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04574341 0,10224475 ! sterol catabolic process GO:0016127 9 8 0,000 0,04574341 0,10214549 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04574341 0,10204641 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04574341 0,10194753 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04574341 0,10184884 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04574341 0,10175034 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04574341 0,10165203 ! prophase GO:0051324 11 8 0,000 0,04574341 0,10155391 ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04574341 0,10145598 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,04574341 0,10135824 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04574341 0,10126068 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04574341 0,10116332 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04574341 0,10106614 ! hormone catabolic process GO:0042447 13 8 0,000 0,04574341 0,10096915 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04574341 0,10087234 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04574341 0,10077572 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04574341 0,10067928 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04574341 0,10058303 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04574341 0,10048696 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04574341 0,10039108 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04574341 0,10029538 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04574341 0,10019986 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04574341 0,10010452 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04574341 0,10000936 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04574341 0,09991439 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04574341 0,09981959 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04574341 0,09972498 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,04574341 0,09963054 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,04794092 0,10431799 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 1,000 0,04794092 0,10421939 ! glycerolipid biosynthetic process GO:0045017 85 60 1,000 0,04794092 0,10412098 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,04794092 0,10402275 ! fertilization GO:0009566 68 60 1,000 0,04794092 0,10392471 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,04938192 0,10694765 ! meiosis GO:0007126 96 61 1,000 0,04938192 0,10684704 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,04938192 0,10674662 ! lipoprotein metabolic process GO:0042157 89 61 1,000 0,04938192 0,10664639 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,04938192 0,10654635 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,04938192 0,10644649 ! neurotransmitter transport GO:0006836 81 62 1,000 0,05083852 0,1094837 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,05083852 0,10938128 ! meiotic cell cycle GO:0051321 97 62 1,000 0,05083852 0,10927906 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,05131364 0,11019736 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,05131364 0,11009457 ! telencephalon cell migration GO:0022029 16 9 0,000 0,05131364 0,10999196 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,05131364 0,10988955 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,05131364 0,10978733 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,05131364 0,10968529 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,05131364 0,10958345 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05131364 0,1094818 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,05131364 0,10938033 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,05131364 0,10927905 ! GTP metabolic process GO:0046039 9 9 0,000 0,05131364 0,10917796 ! elastic fiber assembly GO:0048251 13 9 0,000 0,05131364 0,10907706 ! social behavior GO:0035176 14 9 0,000 0,05131364 0,10897634 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,05131364 0,10887581 ! artery development GO:0060840 19 9 0,000 0,05131364 0,10877546 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,05131364 0,1086753 ! regulation of glycolysis GO:0006110 15 9 0,000 0,05131364 0,10857532 ! response to pain GO:0048265 16 9 0,000 0,05131364 0,10847553 ! protein complex disassembly GO:0043241 17 9 0,000 0,05131364 0,10837592 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,05131364 0,10827649 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,05131364 0,10817725 ! lung alveolus development GO:0048286 17 9 0,000 0,05131364 0,10807818 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,05131364 0,1079793 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,05131364 0,1078806 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,05131364 0,10778208 ! ventral spinal cord development GO:0021517 11 9 0,000 0,05131364 0,10768374 ! protein targeting to ER GO:0045047 19 9 0,000 0,05131364 0,10758558 ! T cell selection GO:0045058 18 9 0,000 0,05131364 0,10748759 ! endoderm development GO:0007492 12 9 0,000 0,05131364 0,10738979 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,05131364 0,10729216 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,05131364 0,10719471 ! arginine catabolic process GO:0006527 10 9 0,000 0,05131364 0,10709744 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,05131364 0,10700034 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,05131364 0,10690342 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,05131364 0,10680668 ! V(D)J recombination GO:0033151 12 9 0,000 0,05131364 0,10671011 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,05131364 0,10661371 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,05131364 0,10651749 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05131364 0,10642144 ! mannose metabolic process GO:0006013 9 9 0,000 0,05131364 0,10632556 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,05131364 0,10622986 ! receptor clustering GO:0043113 15 9 0,000 0,05131364 0,10613433 ! epithelial cell development GO:0002064 10 9 0,000 0,05131364 0,10603897 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,05131364 0,10594378 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,05131364 0,10584877 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,05131364 0,10575392 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,05131364 0,10565924 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,05131364 0,10556474 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,05131364 0,1054704 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,05131364 0,10537623 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,05131364 0,10528223 ! blastoderm segmentation GO:0007350 11 9 0,000 0,05131364 0,10518839 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,05131364 0,10509473 ! DNA ligation GO:0006266 14 9 0,000 0,05131364 0,10500122 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,05131364 0,10490789 ! erythrocyte development GO:0048821 11 9 0,000 0,05131364 0,10481472 ! renal water homeostasis GO:0003091 14 9 0,000 0,05131364 0,10472172 ! postreplication repair GO:0006301 11 9 0,000 0,05131364 0,10462888 ! mRNA cleavage GO:0006379 13 9 0,000 0,05131364 0,10453621 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,05131364 0,1044437 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,05131364 0,10435135 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,05131364 0,10425917 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,05131364 0,10416715 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,05131364 0,10407529 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,05131364 0,10398359 ! acid secretion GO:0046717 14 9 0,000 0,05131364 0,10389206 ! musculoskeletal movement GO:0050881 11 9 0,000 0,05131364 0,10380068 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,05131364 0,10370947 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,05131364 0,10361842 ! purine base metabolic process GO:0006144 18 9 0,000 0,05131364 0,10352752 ! oocyte differentiation GO:0009994 12 9 0,000 0,05131364 0,10343679 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,05131364 0,10334621 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,05131364 0,1032558 ! spleen development GO:0048536 15 9 0,000 0,05131364 0,10316554 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,05131364 0,10307544 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,05131364 0,10298549 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,05131364 0,10289571 ! detection of calcium ion GO:0005513 13 9 0,000 0,05131364 0,10280608 ! blastocyst formation GO:0001825 12 9 0,000 0,05131364 0,1027166 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,05131364 0,10262728 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,05131364 0,10253812 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,05131364 0,10244911 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,05131364 0,10236026 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05131364 0,10227156 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,05131364 0,10218301 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,05131364 0,10209462 ! prepulse inhibition GO:0060134 14 9 0,000 0,05131364 0,10200638 ! embryonic placenta development GO:0001892 12 9 0,000 0,05131364 0,10191829 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,05131364 0,10183035 ! insulin secretion GO:0030073 17 9 0,000 0,05131364 0,10174257 ! sequestering of metal ion GO:0051238 11 9 0,000 0,05131364 0,10165493 ! response to nicotine GO:0035094 16 9 0,000 0,05131364 0,10156745 ! establishment of cell polarity GO:0030010 12 9 0,000 0,05131364 0,10148012 ! nucleus localization GO:0051647 15 9 0,000 0,05131364 0,10139293 ! localization within membrane GO:0051668 15 9 0,000 0,05131364 0,1013059 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,0523105 0,10318538 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,05379764 0,10602791 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,05379764 0,10593713 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,05529971 0,10880182 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,05529971 0,10870882 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,05529971 0,10861599 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,05529971 0,10852331 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,05681649 0,11140488 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,05681649 0,11130998 ! regulation of immune effector process GO:0002697 101 66 1,000 0,05681649 0,11121525 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05685167 0,1111895 ! neuron fate specification GO:0048665 11 10 0,000 0,05685167 0,11109503 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05685167 0,11100072 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05685167 0,11090657 ! thyroid gland development GO:0030878 19 10 0,000 0,05685167 0,11081258 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,05685167 0,11071875 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05685167 0,11062508 ! synapsis GO:0007129 13 10 0,000 0,05685167 0,11053157 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05685167 0,11043822 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05685167 0,11034502 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05685167 0,11025198 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05685167 0,1101591 ! sulfate transport GO:0008272 12 10 0,000 0,05685167 0,11006637 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05685167 0,1099738 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,05685167 0,10988138 ! androgen metabolic process GO:0008209 13 10 0,000 0,05685167 0,10978912 ! phospholipid efflux GO:0033700 16 10 0,000 0,05685167 0,10969702 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,05685167 0,10960507 ! blood vessel remodeling GO:0001974 21 10 0,000 0,05685167 0,10951327 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05685167 0,10942163 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05685167 0,10933014 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,05685167 0,1092388 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05685167 0,10914762 ! pathogenesis GO:0009405 13 10 0,000 0,05685167 0,10905659 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05685167 0,10896571 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05685167 0,10887498 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05685167 0,1087844 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,05685167 0,10869397 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,05685167 0,10860369 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,05685167 0,10851357 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05685167 0,10842359 ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05685167 0,10833376 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,05685167 0,10824408 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05685167 0,10815455 ! response to X-ray GO:0010165 16 10 0,000 0,05685167 0,10806516 ! B cell proliferation GO:0042100 14 10 0,000 0,05685167 0,10797593 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05685167 0,10788684 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05685167 0,1077979 ! forebrain cell migration GO:0021885 17 10 0,000 0,05685167 0,1077091 ! lipid digestion GO:0044241 15 10 0,000 0,05685167 0,10762045 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05685167 0,10753195 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05685167 0,10744359 ! UV protection GO:0009650 14 10 0,000 0,05685167 0,10735537 ! entry into host cell GO:0030260 20 10 0,000 0,05685167 0,10726731 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05685167 0,10717938 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05685167 0,1070916 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05685167 0,10700397 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05685167 0,10691647 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,05685167 0,10682912 ! regulation of bone resorption GO:0045124 24 10 0,000 0,05685167 0,10674192 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,05685167 0,10665485 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05685167 0,10656793 ! regulation of organ growth GO:0046620 11 10 0,000 0,05685167 0,10648115 ! response to dsRNA GO:0043331 18 10 0,000 0,05685167 0,10639451 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05685167 0,10630801 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05685167 0,10622165 ! embryonic axis specification GO:0000578 12 10 0,000 0,05685167 0,10613543 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05685167 0,10604935 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05685167 0,10596341 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05685167 0,10587761 ! cranial nerve development GO:0021545 12 10 0,000 0,05685167 0,10579195 ! fucose catabolic process GO:0019317 16 10 0,000 0,05685167 0,10570642 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05685167 0,10562104 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05685167 0,10553579 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05685167 0,10545068 ! zymogen activation GO:0031638 14 10 0,000 0,05685167 0,10536571 ! salivary gland development GO:0007431 22 10 0,000 0,05685167 0,10528087 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05685167 0,10519618 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05685167 0,10511161 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05685167 0,10502719 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05685167 0,10494289 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,05685167 0,10485874 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05685167 0,10477472 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05685167 0,10469083 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05685167 0,10460708 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05685167 0,10452346 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,05685167 0,10443997 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05685167 0,10435662 ! detection of bacterium GO:0016045 10 10 0,000 0,05685167 0,1042734 ! embryonic gut development GO:0048566 11 10 0,000 0,05685167 0,10419032 ! activation of innate immune response GO:0002218 10 10 0,000 0,05685167 0,10410736 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05685167 0,10402454 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05685167 0,10394185 ! developmental induction GO:0031128 13 10 0,000 0,05685167 0,10385929 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,05685167 0,10377686 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05685167 0,10369457 ! learning or memory GO:0007611 123 68 1,000 0,05989331 0,10915579 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,05989331 0,10906936 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,05989331 0,10898307 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,06145291 0,11173257 ! rRNA transcription GO:0009303 17 11 0,000 0,06235769 0,11328806 ! respiratory burst GO:0045730 14 11 0,000 0,06235769 0,11319865 ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,06235769 0,11310937 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,06235769 0,11302024 ! virus-host interaction GO:0019048 17 11 0,000 0,06235769 0,11293125 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,06235769 0,1128424 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,06235769 0,11275368 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,06235769 0,11266511 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,06235769 0,11257668 ! RNA polyadenylation GO:0043631 19 11 0,000 0,06235769 0,11248838 ! mating GO:0007618 14 11 0,000 0,06235769 0,11240022 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,06235769 0,11231221 ! T cell proliferation GO:0042098 20 11 0,000 0,06235769 0,11222432 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,06235769 0,11213658 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,06235769 0,11204897 ! bone resorption GO:0045453 16 11 0,000 0,06235769 0,1119615 ! regulated secretory pathway GO:0045055 14 11 0,000 0,06235769 0,11187417 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,06235769 0,11178697 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,06235769 0,11169991 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,06235769 0,11161299 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,06235769 0,11152619 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,06235769 0,11143954 ! syncytium formation GO:0006949 15 11 0,000 0,06235769 0,11135302 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,06235769 0,11126663 ! focal adhesion formation GO:0048041 24 11 0,000 0,06235769 0,11118038 ! mitotic spindle organization GO:0007052 15 11 0,000 0,06235769 0,11109426 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,06235769 0,11100827 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,06235769 0,11092242 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,06235769 0,1108367 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,06235769 0,11075111 ! adult heart development GO:0007512 11 11 0,000 0,06235769 0,11066565 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,06235769 0,11058033 ! temperature homeostasis GO:0001659 16 11 0,000 0,06235769 0,11049514 ! L-glutamate transport GO:0015813 16 11 0,000 0,06235769 0,11041007 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,06235769 0,11032514 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,06235769 0,11024034 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,06235769 0,11015567 ! protein homotetramerization GO:0051289 18 11 0,000 0,06235769 0,11007113 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,06235769 0,10998672 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,06235769 0,10990244 ! vasoconstriction GO:0042310 15 11 0,000 0,06235769 0,10981829 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,06235769 0,10973427 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,06235769 0,10965037 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,06235769 0,1095666 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,06235769 0,10948297 ! ribosome assembly GO:0042255 13 11 0,000 0,06235769 0,10939946 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,06235769 0,10931607 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,06235769 0,10923281 ! chromatin silencing GO:0006342 19 11 0,000 0,06235769 0,10914968 ! nucleosome positioning GO:0016584 13 11 0,000 0,06235769 0,10906668 ! T cell homeostasis GO:0043029 20 11 0,000 0,06235769 0,1089838 ! regulation of isotype switching GO:0045191 19 11 0,000 0,06235769 0,10890105 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,06235769 0,10881843 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,06235769 0,10873593 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,06235769 0,10865355 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,06235769 0,1085713 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,06235769 0,10848917 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,06235769 0,10840717 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,06235769 0,10832529 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,06235769 0,10824354 ! male genitalia development GO:0030539 13 11 0,000 0,06235769 0,1081619 ! cholesterol efflux GO:0033344 19 11 0,000 0,06235769 0,1080804 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,06235769 0,10799901 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,06235769 0,10791775 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,06235769 0,10783661 ! germ cell migration GO:0008354 18 11 0,000 0,06235769 0,10775559 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,06235769 0,10767469 ! defense response to fungus GO:0050832 12 11 0,000 0,06235769 0,10759391 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,06235769 0,10751326 ! lysogeny GO:0030069 18 11 0,000 0,06235769 0,10743272 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,06235769 0,10735231 ! acrosome reaction GO:0007340 13 11 0,000 0,06235769 0,10727202 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,06235769 0,10719184 ! amine transport GO:0015837 101 70 1,000 0,06302637 0,10826038 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,06461346 0,1109037 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,06461346 0,11082099 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,06621397 0,11348148 ! lactation GO:0007595 20 12 0,000 0,06783188 0,11616777 ! reproductive cellular process GO:0048610 14 12 0,000 0,06783188 0,11608134 ! tRNA modification GO:0006400 14 12 0,000 0,06783188 0,11599503 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,06783188 0,11590885 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06783188 0,1158228 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,06783188 0,11573688 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06783188 0,11565109 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06783188 0,11556542 ! non-recombinational repair GO:0000726 19 12 0,000 0,06783188 0,11547988 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06783188 0,11539446 ! peroxisomal transport GO:0043574 21 12 0,000 0,06783188 0,11530918 ! cartilage condensation GO:0001502 18 12 0,000 0,06783188 0,11522401 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06783188 0,11513898 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,06783188 0,11505407 ! heart looping GO:0001947 15 12 0,000 0,06783188 0,11496928 ! palate development GO:0060021 15 12 0,000 0,06783188 0,11488462 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,06783188 0,11480008 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06783188 0,11471567 ! arginine metabolic process GO:0006525 13 12 0,000 0,06783188 0,11463139 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06783188 0,11454722 ! methionine metabolic process GO:0006555 13 12 0,000 0,06783188 0,11446318 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06783188 0,11437926 ! Golgi organization GO:0007030 18 12 0,000 0,06783188 0,11429547 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06783188 0,1142118 ! monoamine transport GO:0015844 13 12 0,000 0,06783188 0,11412825 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06783188 0,11404482 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,06783188 0,11396152 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06783188 0,11387833 ! L-amino acid transport GO:0015807 20 12 0,000 0,06783188 0,11379527 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06783188 0,11371233 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06783188 0,11362951 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06783188 0,11354681 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06783188 0,11346423 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06783188 0,11338177 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06783188 0,11329943 ! cerebellum development GO:0021549 13 12 0,000 0,06783188 0,11321721 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06783188 0,11313511 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,06783188 0,11305313 ! histone acetylation GO:0016573 23 12 0,000 0,06783188 0,11297126 ! histone methylation GO:0016571 15 12 0,000 0,06783188 0,11288952 ! autonomic nervous system development GO:0048483 23 12 0,000 0,06783188 0,11280789 ! gland morphogenesis GO:0022612 23 12 0,000 0,06783188 0,11272638 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06783188 0,11264499 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,06783188 0,11256372 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06783188 0,11248256 ! response to gamma radiation GO:0010332 20 12 0,000 0,06783188 0,11240152 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06783188 0,1123206 ! intestinal absorption GO:0050892 19 12 0,000 0,06783188 0,1122398 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06783188 0,11215911 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06783188 0,11207853 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,06783188 0,11199807 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,06783188 0,11191773 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,06783188 0,1118375 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06783188 0,11175739 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06783188 0,11167739 ! microspike assembly GO:0030035 23 12 0,000 0,06783188 0,11159751 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06783188 0,11151774 ! response to cold GO:0009409 14 12 0,000 0,06783188 0,11143808 ! phospholipid biosynthetic process GO:0008654 102 74 1,000 0,06945446 0,11402232 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,06945446 0,11394099 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,06945446 0,11385978 ! response to nutrient GO:0007584 104 75 1,000 0,07109403 0,11646458 ! regulation of ligase activity GO:0051340 114 75 1,000 0,07109403 0,11638168 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,0727462 0,11900161 ! regulation of protein transport GO:0051223 114 76 1,000 0,0727462 0,11891703 GO:0070201|regulation of establishment of protein localization, ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,07327441 0,11969542 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,07327441 0,11961047 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,07327441 0,11952564 ! cGMP metabolic process GO:0046068 16 13 0,000 0,07327441 0,11944093 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,07327441 0,11935634 ! water transport GO:0006833 17 13 0,000 0,07327441 0,11927187 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,07327441 0,11918752 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,07327441 0,11910329 ! lipid localization GO:0010876 24 13 0,000 0,07327441 0,11901918 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,07327441 0,11893518 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,07327441 0,11885131 ! organelle fusion GO:0048284 28 13 0,000 0,07327441 0,11876755 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,07327441 0,11868391 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,07327441 0,11860039 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,07327441 0,11851699 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,07327441 0,1184337 ! response to hexose stimulus GO:0009746 19 13 0,000 0,07327441 0,11835053 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,07327441 0,11826748 ! glutamate metabolic process GO:0006536 18 13 0,000 0,07327441 0,11818454 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,07327441 0,11810172 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,07327441 0,11801902 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,07327441 0,11793643 ! NAD metabolic process GO:0019674 21 13 0,000 0,07327441 0,11785395 ! exocrine system development GO:0035272 27 13 0,000 0,07327441 0,1177716 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,07327441 0,11768935 ! bone mineralization GO:0030282 15 13 0,000 0,07327441 0,11760723 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,07327441 0,11752521 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,07327441 0,11744331 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,07327441 0,11736153 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,07327441 0,11727986 ! genitalia development GO:0048806 15 13 0,000 0,07327441 0,1171983 ! regulation of cellular pH GO:0030641 20 13 0,000 0,07327441 0,11711685 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,07327441 0,11703552 ! tissue regeneration GO:0042246 21 13 0,000 0,07327441 0,11695431 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,07327441 0,1168732 ! cofactor transport GO:0051181 19 13 0,000 0,07327441 0,11679221 ! NADP metabolic process GO:0006739 18 13 0,000 0,07327441 0,11671133 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,07327441 0,11663056 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,07327441 0,1165499 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07327441 0,11646935 ! gas transport GO:0015669 18 13 0,000 0,07327441 0,11638892 ! regulation of RNA stability GO:0043487 28 13 0,000 0,07327441 0,11630859 ! heme biosynthetic process GO:0006783 20 13 0,000 0,07327441 0,11622838 ! regulation of axon extension GO:0030516 23 13 0,000 0,07327441 0,11614828 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,07327441 0,11606829 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,07327441 0,11598841 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,07327441 0,11590863 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,07327441 0,11582897 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,07327441 0,11574942 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,07327441 0,11566998 ! regulation of DNA binding GO:0051101 119 77 1,000 0,07441079 0,11738327 ! protein ubiquitination GO:0016567 125 77 1,000 0,07441079 0,11730281 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,07441079 0,11722247 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,07441079 0,11714224 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,07868549 0,12378702 ! superoxide anion generation GO:0042554 18 14 0,000 0,07868549 0,12370241 ! neuron maturation GO:0042551 21 14 0,000 0,07868549 0,12361791 ! regulation of S phase GO:0033261 18 14 0,000 0,07868549 0,12353353 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,07868549 0,12344926 ! myotube differentiation GO:0014902 21 14 0,000 0,07868549 0,12336511 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,07868549 0,12328108 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,07868549 0,12319715 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,07868549 0,12311335 ! inositol metabolic process GO:0006020 20 14 0,000 0,07868549 0,12302965 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,07868549 0,12294607 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,07868549 0,12286261 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,07868549 0,12277925 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,07868549 0,12269601 ! gene silencing by RNA GO:0031047 20 14 0,000 0,07868549 0,12261289 ! response to cAMP GO:0051591 19 14 0,000 0,07868549 0,12252987 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,07868549 0,12244697 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,07868549 0,12236418 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,07868549 0,1222815 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,07868549 0,12219893 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,07868549 0,12211648 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,07868549 0,12203413 ! glycine metabolic process GO:0006544 22 14 0,000 0,07868549 0,1219519 ! pituitary gland development GO:0021983 23 14 0,000 0,07868549 0,12186978 ! cellular response to starvation GO:0009267 21 14 0,000 0,07868549 0,12178776 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,07868549 0,12170586 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,07868549 0,12162407 ! regulation of heart rate GO:0002027 23 14 0,000 0,07868549 0,12154239 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,07868549 0,12146082 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,07868549 0,12137936 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,07868549 0,121298 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,07868549 0,12121676 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,07868549 0,12113562 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,07868549 0,12105459 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,07868549 0,12097368 ! axon cargo transport GO:0008088 27 14 0,000 0,07868549 0,12089286 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,07868549 0,12081216 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,07868549 0,12073157 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,07868549 0,12065108 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,07868549 0,1205707 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07868549 0,12049043 ! mRNA splice site selection GO:0006376 26 14 0,000 0,07868549 0,12041026 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,07868549 0,1203302 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,07868549 0,12025024 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,07868549 0,1201704 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,07868549 0,12009066 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,07868549 0,12001102 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,07868549 0,11993149 ! muscle maintenance GO:0046716 19 14 0,000 0,07868549 0,11985207 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,07868549 0,11977275 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,07868549 0,11969353 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,07868549 0,11961442 ! cell killing GO:0001906 20 14 0,000 0,07868549 0,11953542 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,07868549 0,11945651 ! cilium assembly GO:0042384 20 14 0,000 0,07868549 0,11937772 ! peptide hormone secretion GO:0030072 23 14 0,000 0,07868549 0,11929902 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,07947703 0,12041975 GO:0010498|proteasomal protein catabolic process, ! mRNA transport GO:0051028 121 81 1,000 0,0811893 0,12293311 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,0811893 0,12285223 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,0811893 0,12277146 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 1,000 0,08291301 0,12529561 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,08406527 0,12695346 ! metencephalon development GO:0022037 19 15 0,000 0,08406527 0,12687016 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,08406527 0,12678697 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,08406527 0,12670388 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,08406527 0,12662091 ! lipid phosphorylation GO:0046834 23 15 0,000 0,08406527 0,12653804 ! bile acid metabolic process GO:0008206 22 15 0,000 0,08406527 0,12645528 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,08406527 0,12637263 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,08406527 0,12629009 ! adult walking behavior GO:0007628 25 15 0,000 0,08406527 0,12620765 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,08406527 0,12612533 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,08406527 0,12604311 ! myoblast differentiation GO:0045445 27 15 0,000 0,08406527 0,12596099 ! centrosome cycle GO:0007098 16 15 0,000 0,08406527 0,12587899 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,08406527 0,12579709 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,08406527 0,12571529 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,08406527 0,12563361 ! cerebral cortex development GO:0021987 29 15 0,000 0,08406527 0,12555203 ! response to osmotic stress GO:0006970 22 15 0,000 0,08406527 0,12547055 ! vesicle coating GO:0006901 25 15 0,000 0,08406527 0,12538919 ! DNA integration GO:0015074 22 15 0,000 0,08406527 0,12530792 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,08406527 0,12522676 ! peptide secretion GO:0002790 27 15 0,000 0,08406527 0,12514571 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,08406527 0,12506476 ! regulation of vasodilation GO:0042312 24 15 0,000 0,08406527 0,12498392 ! neuron recognition GO:0008038 22 15 0,000 0,08406527 0,12490318 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,08406527 0,12482255 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,08406527 0,12474202 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,08406527 0,12466159 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,08406527 0,12458127 ! biomineral formation GO:0031214 18 15 0,000 0,08406527 0,12450105 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,08406527 0,12442093 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,08406527 0,12434092 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,08406527 0,124261 ! organic cation transport GO:0015695 19 15 0,000 0,08406527 0,1241812 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,08406527 0,12410149 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,08406527 0,12402189 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,08406527 0,12394239 ! defense response to virus GO:0051607 27 15 0,000 0,08406527 0,12386299 ! peptide hormone processing GO:0016486 19 15 0,000 0,08406527 0,12378369 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,08406527 0,12370449 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,08639399 0,12704999 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,08815089 0,12955083 ! transcription initiation GO:0006352 118 85 1,000 0,08815089 0,12946811 ! regulation of protein localization GO:0032880 132 85 1,000 0,08815089 0,12938549 ! protein secretion GO:0009306 27 16 0,000 0,08941395 0,13115566 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,08941395 0,13107207 ! hormone secretion GO:0046879 25 16 0,000 0,08941395 0,13098859 ! bone remodeling GO:0046849 24 16 0,000 0,08941395 0,13090521 ! endothelial cell migration GO:0043542 22 16 0,000 0,08941395 0,13082193 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,08941395 0,13073877 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,08941395 0,13065571 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08941395 0,13057275 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,08941395 0,1304899 ! glial cell development GO:0021782 24 16 0,000 0,08941395 0,13040715 ! patterning of blood vessels GO:0001569 24 16 0,000 0,08941395 0,13032451 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,08941395 0,13024198 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,08941395 0,13015954 ! protein polyubiquitination GO:0000209 26 16 0,000 0,08941395 0,13007722 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,08941395 0,12999499 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,08941395 0,12991287 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,08941395 0,12983086 ! fructose metabolic process GO:0006000 20 16 0,000 0,08941395 0,12974895 ! regulation of protein binding GO:0043393 27 16 0,000 0,08941395 0,12966714 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,08941395 0,12958543 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,08941395 0,12950383 ! protein export from nucleus GO:0006611 24 16 0,000 0,08941395 0,12942233 ! negative regulation of immune response GO:0050777 28 16 0,000 0,08941395 0,12934093 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,08941395 0,12925964 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,08941395 0,12917844 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,08941395 0,12909735 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,08941395 0,12901636 ! diencephalon development GO:0021536 25 16 0,000 0,08941395 0,12893547 ! oogenesis GO:0048477 23 16 0,000 0,08941395 0,12885469 ! neural crest cell migration GO:0001755 24 16 0,000 0,08941395 0,128774 ! G1 phase GO:0051318 27 16 0,000 0,08941395 0,12869342 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,08941395 0,12861293 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,08941395 0,12853255 ! steroid catabolic process GO:0006706 22 16 0,000 0,08941395 0,12845227 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,08941395 0,12837209 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,08941395 0,128292 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,08941395 0,12821202 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,08941395 0,12813214 ! sperm-egg recognition GO:0035036 16 16 0,000 0,08941395 0,12805235 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,08941395 0,12797267 ! nerve development GO:0021675 18 16 0,000 0,08941395 0,12789309 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,08941395 0,1278136 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,08941395 0,12773421 ! negative regulation of translation GO:0017148 22 16 0,000 0,08941395 0,12765492 ! cell cycle arrest GO:0007050 150 86 1,000 0,08991849 0,12829562 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,09169661 0,13075152 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,09169661 0,13067051 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,09348506 0,13313662 ! establishment of RNA localization GO:0051236 128 88 1,000 0,09348506 0,13305423 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 1,000 0,09348506 0,13297195 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,0947317 0,13466187 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,0947317 0,13457869 ! negative regulation of defense response GO:0031348 19 17 0,000 0,0947317 0,13449562 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,0947317 0,13441265 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,0947317 0,13432978 ! glycerol metabolic process GO:0006071 20 17 0,000 0,0947317 0,13424701 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,0947317 0,13416435 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,0947317 0,13408178 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,0947317 0,13399932 ! signal complex assembly GO:0007172 29 17 0,000 0,0947317 0,13391696 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,0947317 0,13383471 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,0947317 0,13375255 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,0947317 0,13367049 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,0947317 0,13358853 ! keratinization GO:0031424 17 17 0,000 0,0947317 0,13350668 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,0947317 0,13342492 ! retinoid metabolic process GO:0001523 22 17 0,000 0,0947317 0,13334327 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,0947317 0,13326171 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,0947317 0,13318026 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,0947317 0,1330989 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,0947317 0,13301764 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,0947317 0,13293649 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,0947317 0,13285543 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,0947317 0,13277447 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,0947317 0,13269361 ! membrane budding GO:0006900 29 17 0,000 0,0947317 0,13261284 ! heme metabolic process GO:0042168 27 17 0,000 0,0947317 0,13253218 ! actin filament bundle formation GO:0051017 26 17 0,000 0,0947317 0,13245161 ! body fluid secretion GO:0007589 27 17 0,000 0,0947317 0,13237114 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,0947317 0,13229077 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,0947317 0,1322105 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,0947317 0,13213032 ! sensory perception of pain GO:0019233 23 17 0,000 0,0947317 0,13205024 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,0947317 0,13197026 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,0947317 0,13189038 ! synaptogenesis GO:0007416 24 17 0,000 0,0947317 0,13181059 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,0947317 0,13173089 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,0947317 0,1316513 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,0947317 0,1315718 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,0947317 0,1314924 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,0947317 0,13141309 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,0947317 0,13133388 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,0947317 0,13125476 ! RNA localization GO:0006403 135 91 1,000 0,09891064 0,13696236 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,10001869 0,13841335 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,10001869 0,13833012 ! positive regulation of translation GO:0045727 28 18 0,000 0,10001869 0,13824699 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,10001869 0,13816396 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,10001869 0,13808103 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,10001869 0,13799819 ! cAMP metabolic process GO:0046058 33 18 0,000 0,10001869 0,13791546 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,10001869 0,13783283 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,10001869 0,13775029 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,10001869 0,13766786 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,10001869 0,13758552 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,10001869 0,13750328 ! pancreas development GO:0031016 26 18 0,000 0,10001869 0,13742114 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,10001869 0,1373391 ! glutamine metabolic process GO:0006541 23 18 0,000 0,10001869 0,13725715 ! central nervous system neuron development GO:0021954 30 18 0,000 0,10001869 0,13717531 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,10001869 0,13709356 ! fucose metabolic process GO:0006004 26 18 0,000 0,10001869 0,1370119 ! response to fungus GO:0009620 19 18 0,000 0,10001869 0,13693035 ! peptide cross-linking GO:0018149 31 18 0,000 0,10001869 0,13684889 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,10001869 0,13676753 ! heart process GO:0003015 27 18 0,000 0,10001869 0,13668627 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,10001869 0,1366051 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,10001869 0,13652403 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,10001869 0,13644305 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,10001869 0,13636217 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,10001869 0,13628139 ! vitamin transport GO:0051180 24 18 0,000 0,10001869 0,1362007 ! hormone transport GO:0009914 27 18 0,000 0,10001869 0,13612011 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,10001869 0,13603961 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,10001869 0,13595921 ! cell-cell recognition GO:0009988 20 18 0,000 0,10001869 0,13587891 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,10001869 0,13579869 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,10001869 0,13571858 ! gut development GO:0048565 26 18 0,000 0,10001869 0,13563855 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,10001869 0,13555863 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,10073867 0,13645403 ! cell fate commitment GO:0045165 141 92 1,000 0,10073867 0,13637371 ! positive regulation of immune response GO:0050778 121 92 1,000 0,10073867 0,13629349 ! sulfur metabolic process GO:0006790 118 92 1,000 0,10073867 0,13621337 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,10257615 0,13861642 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,10527511 0,14218012 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,10527511 0,14209668 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,10527511 0,14201334 ! positive regulation of ossification GO:0045778 30 19 0,000 0,10527511 0,1419301 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,10527511 0,14184695 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,10527511 0,14176391 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,10527511 0,14168095 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,10527511 0,1415981 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,10527511 0,14151534 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,10527511 0,14143268 ! regeneration GO:0031099 32 19 0,000 0,10527511 0,14135012 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,10527511 0,14126765 ! sensory perception of taste GO:0050909 23 19 0,000 0,10527511 0,14118528 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,10527511 0,141103 ! smooth muscle contraction GO:0006939 36 19 0,000 0,10527511 0,14102082 ! peroxisome organization GO:0007031 29 19 0,000 0,10527511 0,14093874 ! digestive system process GO:0022600 30 19 0,000 0,10527511 0,14085675 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,10527511 0,14077486 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,10527511 0,14069306 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,10527511 0,14061135 ! response to starvation GO:0042594 30 19 0,000 0,10527511 0,14052975 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,10527511 0,14044823 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,10527511 0,14036681 ! cytolysis GO:0019835 20 19 0,000 0,10527511 0,14028549 ! renal system process GO:0003014 35 19 0,000 0,10527511 0,14020426 ! vasodilation GO:0042311 33 19 0,000 0,10527511 0,14012312 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,10527511 0,14004208 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,10527511 0,13996113 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,10527511 0,13988027 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,10527511 0,13979951 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,10527511 0,13971884 ! sarcomere organization GO:0045214 23 19 0,000 0,10527511 0,13963826 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,10527511 0,13955778 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,10527511 0,13947739 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,10527511 0,13939709 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,10527511 0,13931689 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,10527511 0,13923677 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,10527511 0,13915675 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,10527511 0,13907682 ! protein stabilization GO:0050821 26 19 0,000 0,10527511 0,13899699 ! regulation of binding GO:0051098 151 95 1,000 0,10627883 0,14024171 ! angiogenesis GO:0001525 149 95 1,000 0,10627883 0,1401613 ! carboxylic acid transport GO:0046942 147 95 1,000 0,10627883 0,14008098 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 1,000 0,10814368 0,14245732 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,10814368 0,14237577 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,10814368 0,14229432 ! protein maturation GO:0051604 129 96 1,000 0,10814368 0,14221296 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,11050113 0,14523005 ! iron ion transport GO:0006826 37 20 0,000 0,11050113 0,14514711 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,11050113 0,14506426 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,11050113 0,14498151 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,11050113 0,14489885 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,11050113 0,14481629 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,11050113 0,14473382 ! spinal cord development GO:0021510 31 20 0,000 0,11050113 0,14465145 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,11050113 0,14456916 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,11050113 0,14448698 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,11050113 0,14440488 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,11050113 0,14432288 ! chromosome condensation GO:0030261 31 20 0,000 0,11050113 0,14424097 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,11050113 0,14415916 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,11050113 0,14407743 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,11050113 0,1439958 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,11050113 0,14391426 ! collagen fibril organization GO:0030199 45 20 0,000 0,11050113 0,14383282 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,11050113 0,14375147 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,11050113 0,1436702 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,11050113 0,14358903 ! collagen catabolic process GO:0030574 25 20 0,000 0,11050113 0,14350796 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,11050113 0,14342697 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,11050113 0,14334607 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,11050113 0,14326527 ! alditol metabolic process GO:0019400 24 20 0,000 0,11050113 0,14318456 ! actin filament-based movement GO:0030048 34 20 0,000 0,11050113 0,14310394 ! calcium ion transport GO:0006816 167 99 1,000 0,11379034 0,14728069 ! extracellular structure organization GO:0043062 156 99 1,000 0,11379034 0,14719785 ! divalent metal ion transport GO:0070838 171 100 1,000 0,11568939 0,14957031 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,11568939 0,14948628 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,11569692 0,14941208 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,11569692 0,14932823 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,11569692 0,14924448 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,11569692 0,14916082 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,11569692 0,14907726 GO:0009799|determination of symmetry, ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,11569692 0,14899379 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,11569692 0,14891041 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,11569692 0,14882713 ! protein amino acid acylation GO:0043543 37 21 0,000 0,11569692 0,14874394 ! vesicle docking GO:0048278 27 21 0,000 0,11569692 0,14866084 ! phototransduction GO:0007602 25 21 0,000 0,11569692 0,14857784 ! dendrite development GO:0016358 35 21 0,000 0,11569692 0,14849493 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,11569692 0,14841211 ! ovarian follicle development GO:0001541 30 21 0,000 0,11569692 0,14832938 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,11569692 0,14824675 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,11569692 0,1481642 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,11569692 0,14808175 ! cell aging GO:0007569 32 21 0,000 0,11569692 0,14799939 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,11569692 0,14791712 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,11569692 0,14783495 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,11569692 0,14775286 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,11569692 0,14767087 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,11569692 0,14758897 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,11569692 0,14750716 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,11569692 0,14742543 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,11569692 0,1473438 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,11569692 0,14726226 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,11569692 0,14718081 ! fatty acid transport GO:0015908 30 21 0,000 0,11569692 0,14709945 ! immunoglobulin production GO:0002377 33 21 0,000 0,11569692 0,14701818 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,11569692 0,146937 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,11569692 0,14685591 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,11569692 0,14677491 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,11569692 0,146694 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,11569692 0,14661317 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,11569692 0,14653244 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,11569692 0,14645179 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,11569692 0,14637124 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,11569692 0,14629077 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,11569692 0,14621039 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,11569692 0,1461301 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,11569692 0,14604989 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,12086265 0,15248716 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,12086265 0,15240356 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,12086265 0,15232005 ! viral genome replication GO:0019079 29 22 0,000 0,12086265 0,15223664 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,12086265 0,15215331 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,12086265 0,15207008 ! leukocyte adhesion GO:0007159 38 22 0,000 0,12086265 0,15198693 ! molting cycle process GO:0022404 40 22 0,000 0,12086265 0,15190388 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,12086265 0,15182092 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,12086265 0,15173805 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,12086265 0,15165526 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,12086265 0,15157257 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,12086265 0,15148997 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,12086265 0,15140746 ! lysosome organization GO:0007040 37 22 0,000 0,12086265 0,15132504 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,12086265 0,15124271 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,12086265 0,15116047 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,12086265 0,15107832 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,12086265 0,15099625 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,12086265 0,15091428 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,12086265 0,15083239 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,12086265 0,1507506 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,12086265 0,15066889 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,12086265 0,15058727 ! blastocyst development GO:0001824 37 22 0,000 0,12086265 0,15050574 ! neural tube closure GO:0001843 33 22 0,000 0,12086265 0,1504243 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! protein tetramerization GO:0051262 39 22 0,000 0,12086265 0,15034294 ! neuron fate commitment GO:0048663 32 23 0,000 0,12599851 0,15664679 ! embryonic pattern specification GO:0009880 31 23 0,000 0,12599851 0,15656216 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,12599851 0,15647763 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,12599851 0,15639318 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,12599851 0,15630883 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,12599851 0,15622456 ! osteoblast differentiation GO:0001649 40 23 0,000 0,12599851 0,15614039 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,12599851 0,15605631 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,12599851 0,15597232 ! interaction with host GO:0051701 37 23 0,000 0,12599851 0,15588842 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,12599851 0,1558046 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,12599851 0,15572088 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,12599851 0,15563725 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,12599851 0,15555371 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,12599851 0,15547026 ! pentose metabolic process GO:0019321 31 23 0,000 0,12599851 0,1553869 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,12599851 0,15530363 ! spermatid development GO:0007286 33 23 0,000 0,12599851 0,15522044 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,12599851 0,15513735 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,12599851 0,15505434 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,12599851 0,15497142 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,12599851 0,1548886 ! telomere organization GO:0032200 32 23 0,000 0,12599851 0,15480586 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,12599851 0,15472321 ! regulation of amine transport GO:0051952 38 23 0,000 0,12599851 0,15464064 ! liver development GO:0001889 40 23 0,000 0,12599851 0,15455817 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,13110465 0,16073598 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,13110465 0,16065034 ! initiation of viral infection GO:0019059 42 24 0,000 0,13110465 0,1605648 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,13110465 0,16047935 ! superoxide metabolic process GO:0006801 32 24 0,000 0,13110465 0,16039399 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,13110465 0,16030872 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,13110465 0,16022354 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,13110465 0,16013845 ! fat cell differentiation GO:0045444 37 24 0,000 0,13110465 0,16005345 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,13110465 0,15996854 ! sperm motility GO:0030317 27 24 0,000 0,13110465 0,15988372 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,13110465 0,15979899 ! vacuole organization GO:0007033 39 24 0,000 0,13110465 0,15971435 ! receptor metabolic process GO:0043112 37 24 0,000 0,13110465 0,1596298 ! neural crest cell development GO:0014032 39 24 0,000 0,13110465 0,15954534 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,13110465 0,15946097 ! primary neural tube formation GO:0014020 35 24 0,000 0,13110465 0,15937669 ! negative regulation of cell development GO:0010721 56 24 0,000 0,13110465 0,1592925 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,13110465 0,15920839 ! base-excision repair GO:0006284 31 24 0,000 0,13110465 0,15912438 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,13110465 0,15904045 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,13110465 0,15895661 ! glutathione metabolic process GO:0006749 29 24 0,000 0,13110465 0,15887286 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,13110465 0,1587892 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,13618125 0,16485099 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,13618125 0,16476427 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,13618125 0,16467764 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,13618125 0,16459111 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,13618125 0,16450466 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,13618125 0,16441831 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,13618125 0,16433205 ! peptide transport GO:0015833 43 25 0,000 0,13618125 0,16424587 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,13618125 0,16415979 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,13618125 0,1640738 ! phospholipid transport GO:0015914 35 25 0,000 0,13618125 0,16398789 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,13618125 0,16390208 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,13618125 0,16381636 ! detection of light stimulus GO:0009583 30 25 0,000 0,13618125 0,16373073 ! leukocyte proliferation GO:0070661 39 25 0,000 0,13618125 0,16364518 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,14122848 0,16962168 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,14122848 0,16953315 ! translational initiation GO:0006413 43 26 0,000 0,14122848 0,16944471 ! regulation of pH GO:0006885 36 26 0,000 0,14122848 0,16935637 ! circadian rhythm GO:0007623 42 26 0,000 0,14122848 0,16926811 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,14122848 0,16917995 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,14122848 0,16909188 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,14122848 0,16900391 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,14122848 0,16891602 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,14122848 0,16882823 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,14122848 0,16874052 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,14122848 0,16865291 ! regulation of coagulation GO:0050818 39 26 0,000 0,14122848 0,16856539 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,14624651 0,1744642 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,14624651 0,17437376 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,14624651 0,17428341 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,14624651 0,17419315 ! membrane docking GO:0022406 39 27 0,000 0,14624651 0,17410299 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,14624651 0,17401292 ! acute-phase response GO:0006953 42 27 0,000 0,14624651 0,17392294 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,14624651 0,17383306 ! myofibril assembly GO:0030239 36 27 0,000 0,14624651 0,17374327 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,14624651 0,17365357 ! response to ionizing radiation GO:0010212 47 27 0,000 0,14624651 0,17356397 ! natural killer cell activation GO:0030101 35 27 0,000 0,14624651 0,17347446 ! lipid oxidation GO:0034440 38 27 0,000 0,14624651 0,17338504 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,14624651 0,17329571 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,14624651 0,17320648 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,14624651 0,17311733 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,14624651 0,17302828 ! gene silencing GO:0016458 41 27 0,000 0,14624651 0,17293932 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,1512355 0,178747 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,1512355 0,17865519 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,1512355 0,17856348 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,1512355 0,17847186 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,1512355 0,17838034 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,1512355 0,17828891 GO:0055092|sterol homeostasis, ! complement activation, classical pathway GO:0006958 36 28 0,000 0,1512355 0,17819757 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,1512355 0,17810633 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,1512355 0,17801518 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,1512355 0,17792412 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,1512355 0,17783316 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,1512355 0,17774229 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,1512355 0,17765151 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,1512355 0,17756083 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,1512355 0,17747023 ! BMP signaling pathway GO:0030509 40 28 0,000 0,1512355 0,17737973 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,1512355 0,17728933 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,1512355 0,17719901 ! neural tube formation GO:0001841 41 28 0,000 0,1512355 0,17710879 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,1512355 0,17701865 ! regulation of B cell activation GO:0050864 42 28 0,000 0,1512355 0,17692861 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,15619563 0,1826385 ! regulation of innate immune response GO:0045088 38 29 0,000 0,15619563 0,1825457 ! ovulation cycle process GO:0022602 41 29 0,000 0,15619563 0,18245299 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,15619563 0,18236037 ! protein targeting to membrane GO:0006612 53 29 0,000 0,15619563 0,18226785 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,15619563 0,18217543 ! mismatch repair GO:0006298 34 29 0,000 0,15619563 0,18208309 ! muscle cell development GO:0055001 38 29 0,000 0,15619563 0,18199085 ! eye morphogenesis GO:0048592 51 29 0,000 0,15619563 0,1818987 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,15619563 0,18180665 ! tissue homeostasis GO:0001894 42 29 0,000 0,15619563 0,18171469 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,16112704 0,18735703 ! collagen metabolic process GO:0032963 40 30 0,000 0,16112704 0,18726236 ! organic anion transport GO:0015711 51 30 0,000 0,16112704 0,18716778 ! cholesterol transport GO:0030301 46 30 0,000 0,16112704 0,1870733 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,16112704 0,18697891 ! spliceosome assembly GO:0000245 49 30 0,000 0,16112704 0,18688462 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,16112704 0,18679042 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,16112704 0,18669632 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,16112704 0,18660232 ! ceramide metabolic process GO:0006672 43 30 0,000 0,16112704 0,1865084 ! ovulation cycle GO:0042698 43 30 0,000 0,16112704 0,18641459 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,16112704 0,18632087 ! adult locomotory behavior GO:0008344 47 30 0,000 0,16112704 0,18622724 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,16112704 0,1861337 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,16112704 0,18604026 ! response to heat GO:0009408 41 30 0,000 0,16112704 0,18594691 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,16602992 0,19150894 ! negative regulation of secretion GO:0051048 49 31 0,000 0,16602992 0,19141294 ! glial cell differentiation GO:0010001 55 31 0,000 0,16602992 0,19131705 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,16602992 0,19122124 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,16602992 0,19112554 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,16602992 0,19102993 ! cell fate specification GO:0001708 37 31 0,000 0,16602992 0,19093441 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,16602992 0,19083899 ! RNA modification GO:0009451 40 31 0,000 0,16602992 0,19074367 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,17090443 0,19624572 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,17090443 0,19614779 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,17090443 0,19604996 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,17090443 0,19595223 ! regulation of protein stability GO:0031647 48 32 0,000 0,17090443 0,1958546 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,17090443 0,19575706 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,17090443 0,19565962 ! cytokine production GO:0001816 44 32 0,000 0,17090443 0,19556228 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,17090443 0,19546503 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,17575071 0,20090787 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,17575071 0,20080807 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,17575071 0,20070836 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,17575071 0,20060876 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,17575071 0,20050925 ! actomyosin structure organization GO:0031032 43 33 0,000 0,17575071 0,20040984 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,17575071 0,20031053 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,17575071 0,20021131 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,17575071 0,2001122 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,17575071 0,20001318 ! female gonad development GO:0008585 49 33 0,000 0,17575071 0,19991426 ! positive regulation of cell development GO:0010720 54 33 0,000 0,17575071 0,19981544 ! lipid homeostasis GO:0055088 55 33 0,000 0,17575071 0,19971672 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,17575071 0,1996181 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,17575071 0,19951957 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,17575071 0,19942114 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,18056895 0,20478727 ! mRNA catabolic process GO:0006402 48 34 0,000 0,18056895 0,20468634 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,18056895 0,20458551 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,18056895 0,20448478 ! feeding behavior GO:0007631 45 34 0,000 0,18056895 0,20438415 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,18056895 0,20428362 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,18056895 0,20418318 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,18056895 0,20408285 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,18056895 0,20398261 ! female gamete generation GO:0007292 43 34 0,000 0,18056895 0,20388247 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,18056895 0,20378243 ! polyol metabolic process GO:0019751 44 34 0,000 0,18056895 0,20368249 ! aerobic respiration GO:0009060 47 34 0,000 0,18056895 0,20358264 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,18056895 0,2034829 ! embryonic organ development GO:0048568 45 34 0,000 0,18056895 0,20338325 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,18056895 0,2032837 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,1853593 0,20857455 ! Notch signaling pathway GO:0007219 56 35 0,000 0,1853593 0,20847256 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,1853593 0,20837067 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,1853593 0,20826888 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,1853593 0,20816718 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,1853593 0,20806559 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,1853593 0,20796409 ! glycogen metabolic process GO:0005977 48 35 0,000 0,1853593 0,20786269 ! pigment metabolic process GO:0042440 61 35 0,000 0,1853593 0,2077614 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,1853593 0,2076602 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,1853593 0,2075591 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,19012191 0,21278852 GO:0090047|positive regulation of transcription regulator activity, ! regulation of hormone secretion GO:0046883 48 36 0,000 0,19012191 0,21268502 ! organic ether metabolic process GO:0018904 46 36 0,000 0,19012191 0,21258163 ! tissue remodeling GO:0048771 62 36 0,000 0,19012191 0,21247833 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,19012191 0,21237513 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,19012191 0,21227204 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,19012191 0,21216905 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,19012191 0,21206615 ! glucan metabolic process GO:0044042 49 36 0,000 0,19012191 0,21196336 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,19485696 0,21713711 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,19485696 0,21703196 ! ion transmembrane transport GO:0034220 56 37 0,000 0,19485696 0,21692691 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,19485696 0,21682197 ! regulation of protein secretion GO:0050708 51 37 0,000 0,19485696 0,21671712 ! amino acid activation GO:0043038 52 37 0,000 0,19485696 0,21661237 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,19485696 0,21650773 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,19956459 0,22163136 ! gliogenesis GO:0042063 71 38 0,000 0,19956459 0,2215244 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,19956459 0,22141753 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,19956459 0,22131078 ! phagocytosis GO:0006909 60 38 0,000 0,19956459 0,22120412 ! mesenchymal cell development GO:0014031 64 38 0,000 0,19956459 0,22109757 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,20424496 0,226174 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,20424496 0,22606516 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,20424496 0,22595642 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,20424496 0,22584779 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,20424496 0,22573926 ! chromatin remodeling GO:0006338 68 39 0,000 0,20424496 0,22563084 ! developmental growth GO:0048589 62 39 0,000 0,20424496 0,22552252 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,20889823 0,23054987 ! response to calcium ion GO:0051592 58 40 0,000 0,20889823 0,23043929 ! regulation of tube size GO:0035150 60 40 0,000 0,20889823 0,23032883 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,20889823 0,23021846 ! peptide metabolic process GO:0006518 56 40 0,000 0,20889823 0,2301082 ! inner ear development GO:0048839 57 40 0,000 0,20889823 0,22999805 ! T cell differentiation GO:0030217 65 40 0,000 0,20889823 0,229888 ! double-strand break repair GO:0006302 67 40 0,000 0,20889823 0,22977806 ! B cell differentiation GO:0030183 62 40 0,000 0,20889823 0,22966823 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,20889823 0,22955849 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,21352456 0,23453032 ! glucose transport GO:0015758 52 41 0,000 0,21352456 0,23441837 ! endosome transport GO:0016197 71 41 0,000 0,21352456 0,23430653 ! striated muscle contraction GO:0006941 62 41 0,000 0,21352456 0,23419479 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,21352456 0,23408316 ! mitochondrial transport GO:0006839 60 42 0,000 0,21812409 0,23901163 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,21812409 0,23889781 ! hexose transport GO:0008645 54 42 0,000 0,21812409 0,23878411 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,21812409 0,23867051 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,21812409 0,23855702 ! excretion GO:0007588 63 42 0,000 0,21812409 0,23844364 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,21812409 0,23833036 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,21812409 0,23821719 ! positive regulation of binding GO:0051099 59 43 0,000 0,22269699 0,24309591 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,22269699 0,24298059 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,22269699 0,24286538 ! tRNA processing GO:0008033 49 43 0,000 0,22269699 0,24275027 ! vesicle organization GO:0016050 79 43 0,000 0,22269699 0,24263528 ! response to insulin stimulus GO:0032868 63 43 0,000 0,22269699 0,2425204 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,22269699 0,24240562 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,2272434 0,24723738 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,2272434 0,24712049 ! glycolysis GO:0006096 53 44 0,000 0,2272434 0,2470037 ! regulation of ion transport GO:0043269 57 44 0,000 0,2272434 0,24688702 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,2272434 0,24677046 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,2272434 0,246654 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,2272434 0,24653765 ! RNA catabolic process GO:0006401 64 45 0,000 0,23176348 0,25132297 ! regulation of translational initiation GO:0006446 64 45 0,000 0,23176348 0,25120453 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,23176348 0,25108621 ! cell recognition GO:0008037 58 45 0,000 0,23176348 0,25096799 ! cell maturation GO:0048469 60 45 0,000 0,23176348 0,25084989 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,23625738 0,25559359 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,23625738 0,25547343 ! cell redox homeostasis GO:0045454 63 46 0,000 0,23625738 0,25535338 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,23625738 0,25523343 ! regulation of ossification GO:0030278 71 46 0,000 0,23625738 0,25511361 ! histone modification GO:0016570 68 46 0,000 0,23625738 0,25499389 ! viral infectious cycle GO:0019058 71 47 0,000 0,24072525 0,25969422 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,24072525 0,25957247 ! endocrine system development GO:0035270 83 47 0,000 0,24072525 0,25945083 ! covalent chromatin modification GO:0016569 75 47 0,000 0,24072525 0,25932931 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,24072525 0,2592079 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,24072525 0,25908661 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,24072525 0,25896543 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,24072525 0,25884436 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,24072525 0,2587234 ! chloride transport GO:0006821 67 48 0,000 0,24516724 0,26337443 ! response to temperature stimulus GO:0009266 62 48 0,000 0,24516724 0,26325147 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,24516724 0,26312863 ! heart morphogenesis GO:0003007 65 48 0,000 0,24516724 0,2630059 ! regulation of DNA replication GO:0006275 75 48 0,000 0,24516724 0,26288329 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,24516724 0,26276079 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,24516724 0,2626384 ! regulation of endocytosis GO:0030100 63 48 0,000 0,24516724 0,26251613 ! nuclear export GO:0051168 69 48 0,000 0,24516724 0,26239397 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,24958349 0,26699629 ! sensory perception of smell GO:0007608 61 49 0,000 0,24958349 0,26687217 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,24958349 0,26674815 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,24958349 0,26662426 ! RNA elongation GO:0006354 62 49 0,000 0,24958349 0,26650048 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,24958349 0,26637681 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,24958349 0,26625326 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,24958349 0,26612982 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,25397416 0,27068608 ! lipid modification GO:0030258 73 50 0,000 0,25397416 0,2705607 ! proton transport GO:0015992 75 50 0,000 0,25397416 0,27043544 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,25397416 0,2703103 ! hydrogen transport GO:0006818 77 51 0,000 0,25833938 0,27482913 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,25833938 0,27470207 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 0,000 0,25833938 0,27457513 ! adult behavior GO:0030534 80 51 0,000 0,25833938 0,27444831 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,25833938 0,2743216 ! transition metal ion transport GO:0000041 74 52 0,000 0,26267932 0,27880131 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,26267932 0,27867271 ! aging GO:0007568 79 52 0,000 0,26267932 0,27854423 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,26267932 0,27841587 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,26267932 0,27828762 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,2669941 0,28272856 ! cell projection assembly GO:0030031 76 53 0,000 0,2669941 0,28259845 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,27128388 0,28700687 ! glucose catabolic process GO:0006007 66 54 0,000 0,27128388 0,28687491 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,27128388 0,28674308 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,27128388 0,28661136 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,27128388 0,28647977 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,27128388 0,28634829 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,2755488 0,29071663 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,2755488 0,29058333 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,27978901 0,29491967 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,27978901 0,29478457 ! carbohydrate transport GO:0008643 74 57 0,000 0,28400464 0,29908913 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,28400464 0,29895225 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,28400464 0,29881549 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,28400464 0,29867886 ! secondary metabolic process GO:0019748 84 57 0,000 0,28400464 0,29854235 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,28400464 0,29840597 ! developmental maturation GO:0021700 75 57 0,000 0,28400464 0,29826971 ! viral reproductive process GO:0022415 87 58 0,000 0,28819583 0,30253327 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,28819583 0,30239526 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,29236273 0,30662757 ! lung development GO:0030324 94 59 0,000 0,29236273 0,30648782 ! actin filament organization GO:0007015 95 59 0,000 0,29236273 0,30634819 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,29236273 0,30620868 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,29236273 0,30606931 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,29650547 0,31026505 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,30062419 0,31443185 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,30062419 0,31428893 ! extracellular matrix organization GO:0030198 103 61 0,000 0,30062419 0,31414614 ! amine catabolic process GO:0009310 90 62 0,000 0,30471904 0,31828056 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,30471904 0,31813608 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,30471904 0,31799174 ! respiratory tube development GO:0030323 99 62 0,000 0,30471904 0,31784753 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,30471904 0,31770344 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,30879015 0,32180215 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,30879015 0,3216564 ! viral reproduction GO:0016032 92 63 0,000 0,30879015 0,32151079 ! regulation of lipase activity GO:0060191 109 63 0,000 0,30879015 0,32136531 ! negative regulation of cell size GO:0045792 108 64 0,000 0,31283765 0,32543039 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,31283765 0,32528327 ! hexose catabolic process GO:0019320 82 64 0,000 0,31283765 0,32513628 ! respiratory system development GO:0060541 100 64 0,000 0,31283765 0,32498943 ! adaptive immune response GO:0002250 94 64 0,000 0,31283765 0,3248427 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! B cell activation GO:0042113 104 65 0,000 0,31686168 0,32887268 ! defense response to bacterium GO:0042742 73 65 0,000 0,31686168 0,32872434 ! activation of immune response GO:0002253 83 65 0,000 0,31686168 0,32857613 ! protein oligomerization GO:0051259 100 65 0,000 0,31686168 0,32842806 ! antigen processing and presentation GO:0019882 96 66 0,000 0,32086237 0,33242498 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,32086237 0,33227531 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,32483987 0,33624289 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,32483987 0,33609163 ! acute inflammatory response GO:0002526 92 68 0,000 0,32879429 0,34003007 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,32879429 0,33987725 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,32879429 0,33972456 ! rhythmic process GO:0048511 105 68 0,000 0,32879429 0,33957201 ! inorganic anion transport GO:0015698 93 68 0,000 0,32879429 0,3394196 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,33272578 0,34332405 ! response to metal ion GO:0010038 103 70 0,000 0,33663447 0,34720147 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,33663447 0,34704585 ! humoral immune response GO:0006959 86 70 0,000 0,33663447 0,34689036 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,33663447 0,34673501 ! muscle cell differentiation GO:0042692 104 71 0,000 0,34052049 0,35058062 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,34052049 0,35042377 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,34052049 0,35026705 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,34052049 0,35011047 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,34052049 0,34995403 ! response to hypoxia GO:0001666 132 72 0,000 0,34438396 0,35376646 ! regulation of blood pressure GO:0008217 107 73 0,000 0,34822502 0,35755247 ! tube morphogenesis GO:0035239 118 73 0,000 0,34822502 0,35739292 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,34822502 0,35723351 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,34822502 0,35707425 ! response to oxygen levels GO:0070482 137 74 0,000 0,35204379 0,3608292 ! digestion GO:0007586 97 74 0,000 0,35204379 0,36066847 ! protein import into nucleus GO:0006606 118 74 0,000 0,35204379 0,36050789 ! response to inorganic substance GO:0010035 115 75 0,000 0,35584041 0,36423362 ! negative regulation of growth GO:0045926 123 75 0,000 0,35584041 0,36407159 ! nuclear import GO:0051170 121 75 0,000 0,35584041 0,36390971 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,35584041 0,36374797 ! amine biosynthetic process GO:0009309 97 76 0,000 0,359615 0,36744313 ! tRNA metabolic process GO:0006399 95 76 0,000 0,359615 0,36727997 ! response to unfolded protein GO:0006986 99 76 0,000 0,359615 0,36711695 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,36336769 0,37078335 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,36336769 0,37061893 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,3670986 0,37425832 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,3670986 0,3740925 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,37080785 0,37770508 ! T cell activation GO:0042110 134 79 0,000 0,37080785 0,37753788 ! regulation of lyase activity GO:0051339 133 79 0,000 0,37080785 0,37737083 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,37080785 0,37720392 ! chromatin assembly GO:0031497 102 80 0,000 0,37449559 0,38078685 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,37449559 0,38061858 ! protein localization in nucleus GO:0034504 133 80 0,000 0,37449559 0,38045046 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,37449559 0,38028249 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,37816192 0,38383601 ! response to protein stimulus GO:0051789 111 81 0,000 0,37816192 0,3836667 ! vitamin metabolic process GO:0006766 103 81 0,000 0,37816192 0,38349753 ! ossification GO:0001503 134 82 0,000 0,38180696 0,38702337 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,38543085 0,39052465 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,38903371 0,39400155 ! sterol metabolic process GO:0016125 120 84 0,000 0,38903371 0,39382814 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,39261565 0,39727936 ! rRNA metabolic process GO:0016072 107 85 0,000 0,39261565 0,39710466 GO:0006364|rRNA processing, ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,39261565 0,3969301 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,39617679 0,4003544 ! nucleosome organization GO:0034728 114 87 0,000 0,39971726 0,4037548 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,39971726 0,40357756 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,39971726 0,40340048 ! female pregnancy GO:0007565 130 87 0,000 0,39971726 0,40322355 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,40323717 0,406596 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,40323717 0,40641783 GO:0016054|organic acid catabolic process, ! regulation of neurogenesis GO:0050767 153 89 0,000 0,40673664 0,40976534 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,40673664 0,40958593 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,40673664 0,40940668 ! leukocyte differentiation GO:0002521 143 90 0,000 0,41021579 0,41272805 ! hormone metabolic process GO:0042445 121 90 0,000 0,41021579 0,41254758 ! ATP metabolic process GO:0046034 137 91 0,000 0,41367473 0,41584436 ! response to virus GO:0009615 122 91 0,000 0,41367473 0,41566269 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,41711359 0,41893505 ! DNA recombination GO:0006310 146 92 0,000 0,41711359 0,41875219 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,42053248 0,4220003 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,42053248 0,42181627 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,43401058 0,43514574 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! protein import GO:0017038 156 99 0,000 0,44063275 0,44159273 ! regulation of translation GO:0006417 151 100 0,000 0,44391501 0,44468838 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,44391501 0,44449478 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,44391501 0,44430135 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,44391501 0,4441081 ! protein localization in organelle GO:0033365 161 100 0,000 0,44391501 0,44391501