pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6598-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! S phase GO:0051320 9 9 4,000 2,507E-10 6,033E-07 GO:0000084|S phase of mitotic cell cycle, ! mitotic sister chromatid segregation GO:0000070 57 36 5,000 1,573E-08 1,892E-05 ! sister chromatid segregation GO:0000819 58 37 5,000 1,87E-08 1,5E-05 ! pigmentation GO:0043473 100 46 5,000 7,282E-08 4,38E-05 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 4,000 9,959E-08 4,792E-05 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 3,000 4,318E-07 1,732E-04 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 4,000 6,782E-07 2,331E-04 ! chromosome segregation GO:0007059 113 67 5,000 7,161E-07 2,154E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 2,125E-06 5,682E-04 ! ATP synthesis coupled electron transport GO:0042773 64 45 4,000 2,125E-06 5,114E-04 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 3,394E-06 7,424E-04 ! activation of pro-apoptotic gene products GO:0008633 47 23 3,000 3,698E-06 7,414E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 4,421E-06 8,183E-04 ! respiratory electron transport chain GO:0022904 76 53 4,000 4,845E-06 8,327E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 6,176E-06 9,906E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 6,176E-06 9,287E-04 GO:0045936|negative regulation of phosphate metabolic process, ! induction of positive chemotaxis GO:0050930 15 9 2,000 8,091E-06 1,145E-03 ! negative regulation of protein modification process GO:0031400 60 28 3,000 8,397E-06 1,122E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 8,397E-06 1,063E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,152E-05 1,386E-03 ! protein sumoylation GO:0016925 15 10 2,000 1,152E-05 1,32E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 1,579E-05 1,726E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 1,579E-05 1,651E-03 GO:0010829|negative regulation of glucose transport, ! regulation of positive chemotaxis GO:0050926 19 12 2,000 2,098E-05 2,103E-03 GO:0050927|positive regulation of positive chemotaxis, ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 3,000 2,347E-05 2,259E-03 ! blood coagulation GO:0007596 146 78 4,000 3,248E-05 3,005E-03 GO:0050817|coagulation, ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 3,447E-05 3,072E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 4,294E-05 3,69E-03 ! dopamine metabolic process GO:0042417 35 15 2,000 4,294E-05 3,562E-03 ! hemostasis GO:0007599 158 84 4,000 4,644E-05 3,725E-03 ! oxidative phosphorylation GO:0006119 133 86 4,000 5,2E-05 4,036E-03 ! cellular respiration GO:0045333 135 88 4,000 5,806E-05 4,366E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 6,374E-05 4,647E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 7,561E-05 5,351E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 8,367E-05 5,752E-03 ! pigmentation during development GO:0048066 41 19 2,000 9,021E-05 6,029E-03 ! interphase GO:0051325 213 98 4,000 9,698E-05 6,307E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,058E-04 6,697E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,058E-04 6,525E-03 GO:0010827|regulation of glucose transport, ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,23E-04 7,397E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 1,23E-04 7,216E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 1,23E-04 7,045E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 1,419E-04 7,94E-03 ! platelet activation GO:0030168 37 23 2,000 1,626E-04 8,893E-03 ! regulation of behavior GO:0050795 43 24 2,000 1,852E-04 9,904E-03 ! myelination GO:0042552 45 25 2,000 2,098E-04 0,0109726 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,126E-04 0,01088295 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,126E-04 0,01065622 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,126E-04 0,01043875 ! valine metabolic process GO:0006573 10 5 1,000 2,126E-04 0,01022997 ! paraxial mesoderm development GO:0048339 14 5 1,000 2,126E-04 0,01002939 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 1,000 2,126E-04 9,837E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,126E-04 9,651E-03 ! neural tube patterning GO:0021532 7 5 1,000 2,126E-04 9,472E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 2,126E-04 9,3E-03 GO:0051930|regulation of sensory perception of pain, ! phospholipid scrambling GO:0017121 8 5 1,000 2,126E-04 9,134E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 2,65E-04 0,01118499 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 2,732E-04 0,01133195 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 2,732E-04 0,01113988 ! negative regulation of kinase activity GO:0033673 131 68 3,000 2,892E-04 0,01159714 ! sleep GO:0030431 13 6 1,000 3,179E-04 0,01253945 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 1,000 3,179E-04 0,0123372 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 3,179E-04 0,01214138 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! attachment of GPI anchor to protein GO:0016255 15 6 1,000 3,179E-04 0,01195167 ! positive regulation of exocytosis GO:0045921 8 6 1,000 3,179E-04 0,0117678 ! establishment of spindle localization GO:0051293 12 6 1,000 3,179E-04 0,0115895 GO:0051653|spindle localization, ! positive regulation of cytokine production during immune response GO:0002720 9 6 1,000 3,179E-04 0,01141652 ! catechol metabolic process GO:0009712 54 29 2,000 3,288E-04 0,01163296 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 3,601E-04 0,01255784 ! negative regulation of transferase activity GO:0051348 140 72 3,000 3,601E-04 0,01237845 ! phenol metabolic process GO:0018958 55 30 2,000 3,641E-04 0,01233735 ! ensheathment of neurons GO:0007272 57 30 2,000 3,641E-04 0,01216599 GO:0008366|axon ensheathment, ! eye development GO:0001654 143 74 3,000 3,999E-04 0,01318052 ! mesoderm formation GO:0001707 69 31 2,000 4,017E-04 0,01306098 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 4,418E-04 0,01417172 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 1,000 4,437E-04 0,0140474 ! prostate gland development GO:0030850 13 7 1,000 4,437E-04 0,01386497 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 4,437E-04 0,01368721 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 4,437E-04 0,01351396 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 1,000 4,437E-04 0,01334503 ! formation of primary germ layer GO:0001704 72 33 2,000 4,843E-04 0,0143852 ! leukocyte chemotaxis GO:0030595 50 33 2,000 4,843E-04 0,01420977 GO:0060326|cell chemotaxis, ! positive regulation of phosphorylation GO:0042327 129 79 3,000 5,129E-04 0,01486862 ! regulation of synaptic transmission GO:0050804 134 79 3,000 5,129E-04 0,01469162 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 5,294E-04 0,01498387 ! mesoderm morphogenesis GO:0048332 76 34 2,000 5,294E-04 0,01480964 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 5,639E-04 0,01559506 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of muscle development GO:0048634 70 35 2,000 5,77E-04 0,01577623 ! regulation of synaptic plasticity GO:0048167 64 35 2,000 5,77E-04 0,01559897 ! succinate metabolic process GO:0006105 14 8 1,000 5,898E-04 0,0157681 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 5,898E-04 0,01559483 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 1,000 5,898E-04 0,01542532 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 5,898E-04 0,01525945 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,898E-04 0,01509712 ! response to drug GO:0042493 143 82 3,000 5,907E-04 0,01496048 ! negative regulation of transport GO:0051051 153 84 3,000 6,47E-04 0,01621534 ! regulation of transmission of nerve impulse GO:0051969 141 84 3,000 6,47E-04 0,01604817 ! mitochondrion organization GO:0007005 148 86 3,000 7,07E-04 0,01735715 ! regulation of developmental growth GO:0048638 15 9 1,000 7,56E-04 0,01837407 ! keratinocyte proliferation GO:0043616 14 9 1,000 7,56E-04 0,01819033 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 7,56E-04 0,01801023 ! middle ear morphogenesis GO:0042474 14 9 1,000 7,56E-04 0,01783365 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 7,56E-04 0,01766051 ! phosphagen metabolic process GO:0006599 12 9 1,000 7,56E-04 0,0174907 GO:0006600|creatine metabolic process, ! motor axon guidance GO:0008045 16 9 1,000 7,56E-04 0,01732412 ! response to amine stimulus GO:0014075 13 9 1,000 7,56E-04 0,01716069 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of cell division GO:0051302 15 9 1,000 7,56E-04 0,01700031 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 7,56E-04 0,0168429 ! regulation of synaptogenesis GO:0051963 15 9 1,000 7,56E-04 0,01668837 ! regulation of telomere maintenance GO:0032204 14 9 1,000 7,56E-04 0,01653666 ! positive regulation of protein modification process GO:0031401 136 88 3,000 7,708E-04 0,01670766 ! gland development GO:0048732 206 88 3,000 7,708E-04 0,01655849 ! regulation of neurological system process GO:0031644 148 88 3,000 7,708E-04 0,01641195 ! mammary gland development GO:0030879 86 39 2,000 7,948E-04 0,01677543 ! regulation of action potential in neuron GO:0019228 73 39 2,000 7,948E-04 0,01662955 ! cytokinesis GO:0000910 72 40 2,000 8,564E-04 0,01776255 ! dorsal/ventral pattern formation GO:0009953 68 41 2,000 9,209E-04 0,01893672 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 9,422E-04 0,0192107 ! apical protein localization GO:0045176 15 10 1,000 9,422E-04 0,01904926 ! midbrain development GO:0030901 13 10 1,000 9,422E-04 0,01889052 ! regulation of membrane potential GO:0042391 164 93 3,000 9,48E-04 0,01885022 ! forebrain development GO:0030900 188 95 3,000 1,026E-03 0,02023961 ! epithelial cell differentiation GO:0030855 79 43 2,000 1,059E-03 0,02071254 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 1,059E-03 0,0205455 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,148E-03 0,02209736 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,148E-03 0,02192198 ! melanocyte differentiation GO:0030318 21 11 1,000 1,148E-03 0,02174937 GO:0050931|pigment cell differentiation, ! indolalkylamine metabolic process GO:0006586 17 11 1,000 1,148E-03 0,02157945 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 1,148E-03 0,02141217 ! DNA methylation GO:0006306 19 11 1,000 1,148E-03 0,02124746 GO:0006305|DNA alkylation, ! regulation of embryonic development GO:0045995 27 11 1,000 1,148E-03 0,02108526 ! regulation of synapse organization GO:0050807 17 11 1,000 1,148E-03 0,02092553 ! leukocyte migration GO:0050900 68 45 2,000 1,209E-03 0,02187635 ! epidermal cell differentiation GO:0009913 68 46 2,000 1,289E-03 0,0231494 ! positive regulation of defense response GO:0031349 76 47 2,000 1,373E-03 0,02446159 ! JNK cascade GO:0007254 91 47 2,000 1,373E-03 0,02428173 ! hippocampus development GO:0021766 26 12 1,000 1,373E-03 0,02412051 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,373E-03 0,02394573 ! asymmetric protein localization GO:0008105 20 12 1,000 1,373E-03 0,02377345 ! synaptic vesicle exocytosis GO:0016079 19 12 1,000 1,373E-03 0,02360364 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,373E-03 0,02343624 GO:0042130|negative regulation of T cell proliferation, ! regulation of synapse structure and activity GO:0050803 18 12 1,000 1,373E-03 0,0232712 ! regulation of inflammatory response GO:0050727 75 48 2,000 1,459E-03 0,02454936 ! regulation of action potential GO:0001508 95 49 2,000 1,549E-03 0,02588103 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 2,000 1,549E-03 0,02570254 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 1,549E-03 0,02552649 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 1,618E-03 0,026486 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,618E-03 0,02630704 ! plasma membrane organization GO:0007009 24 13 1,000 1,618E-03 0,02613049 ! cell-cell junction assembly GO:0007043 27 13 1,000 1,618E-03 0,02595628 ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 1,618E-03 0,02578439 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 1,618E-03 0,02561475 ! regulation of angiogenesis GO:0045765 114 52 2,000 1,839E-03 0,02892352 ! regulation of muscle contraction GO:0006937 81 52 2,000 1,839E-03 0,0287357 ! positive regulation of growth GO:0045927 90 52 2,000 1,839E-03 0,02855031 ! cartilage development GO:0051216 90 52 2,000 1,839E-03 0,02836729 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,882E-03 0,02884412 ! stem cell development GO:0048864 43 14 1,000 1,882E-03 0,02866157 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 1,882E-03 0,02848131 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,882E-03 0,0283033 ! regulation of protein catabolic process GO:0042176 116 55 2,000 2,161E-03 0,0322997 ! gastrulation GO:0007369 112 55 2,000 2,161E-03 0,03210032 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 2,165E-03 0,03195908 ! ER-associated protein catabolic process GO:0030433 24 15 1,000 2,165E-03 0,03176421 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 1,000 2,165E-03 0,0315717 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 1,000 2,165E-03 0,03138151 ! regulation of exocytosis GO:0017157 22 15 1,000 2,165E-03 0,03119359 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 2,165E-03 0,03100792 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 2,394E-03 0,03408744 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 2,467E-03 0,03491422 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 2,467E-03 0,03471004 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 2,467E-03 0,03450824 ! startle response GO:0001964 28 16 1,000 2,467E-03 0,03430877 ! DNA replication initiation GO:0006270 27 16 1,000 2,467E-03 0,0341116 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,467E-03 0,03391667 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! cytokine-mediated signaling pathway GO:0019221 97 59 2,000 2,642E-03 0,03612124 ! establishment of organelle localization GO:0051656 109 59 2,000 2,642E-03 0,03591716 ! regulation of heart contraction GO:0008016 110 60 2,000 2,772E-03 0,03746835 ! camera-type eye development GO:0043010 116 60 2,000 2,772E-03 0,03725903 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 2,772E-03 0,03705204 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,787E-03 0,03705171 ! limbic system development GO:0021761 36 17 1,000 2,787E-03 0,03684813 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 2,787E-03 0,03664678 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,787E-03 0,03644761 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 2,787E-03 0,0362506 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,787E-03 0,0360557 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 2,787E-03 0,03586289 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 2,787E-03 0,03567213 ! mesoderm development GO:0007498 119 61 2,000 2,906E-03 0,03698774 ! regulation of homeostatic process GO:0032844 134 62 2,000 3,043E-03 0,03853357 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 3,126E-03 0,03938079 ! memory GO:0007613 31 18 1,000 3,126E-03 0,03917568 ! response to retinoic acid GO:0032526 26 18 1,000 3,126E-03 0,0389727 ! positive regulation of synaptic transmission GO:0050806 28 18 1,000 3,126E-03 0,03877181 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 3,479E-03 0,04292614 GO:0035113|embryonic appendage morphogenesis, ! skin development GO:0043588 36 19 1,000 3,483E-03 0,04276075 ! forelimb morphogenesis GO:0035136 32 19 1,000 3,483E-03 0,04254369 ! regulation of postsynaptic membrane potential GO:0060078 32 19 1,000 3,483E-03 0,04232882 ! response to vitamin A GO:0033189 27 19 1,000 3,483E-03 0,04211611 ! neuromuscular junction development GO:0007528 34 19 1,000 3,483E-03 0,04190553 ! plasma membrane fusion GO:0045026 28 19 1,000 3,483E-03 0,04169705 ! visual learning GO:0008542 36 19 1,000 3,483E-03 0,04149063 ! cellular pigmentation GO:0033059 36 19 1,000 3,483E-03 0,04128624 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 3,483E-03 0,04108386 ! cell-cell junction organization GO:0045216 35 19 1,000 3,483E-03 0,04088345 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 3,483E-03 0,04068498 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 1,000 3,483E-03 0,04048844 ! proximal/distal pattern formation GO:0009954 32 19 1,000 3,483E-03 0,04029378 ! activation of MAPK activity GO:0000187 115 67 2,000 3,79E-03 0,04362931 ! response to vitamin GO:0033273 31 20 1,000 3,859E-03 0,04420984 ! response to alkaloid GO:0043279 38 20 1,000 3,859E-03 0,04400031 ! stem cell differentiation GO:0048863 53 20 1,000 3,859E-03 0,04379277 ! regulation of interleukin-2 production GO:0032663 35 20 1,000 3,859E-03 0,04358717 ! positive regulation of neurological system process GO:0031646 32 20 1,000 3,859E-03 0,04338349 ! negative regulation of T cell activation GO:0050868 40 20 1,000 3,859E-03 0,0431817 ! urogenital system development GO:0001655 137 69 2,000 4,117E-03 0,04586092 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 4,252E-03 0,04714374 ! axis specification GO:0009798 38 21 1,000 4,252E-03 0,04692749 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 4,252E-03 0,0467132 ! DNA modification GO:0006304 34 21 1,000 4,252E-03 0,04650087 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 4,252E-03 0,04629046 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 4,252E-03 0,04608195 ! appendage morphogenesis GO:0035107 135 70 2,000 4,287E-03 0,04625418 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 2,000 4,461E-03 0,04791745 ! appendage development GO:0048736 136 71 2,000 4,461E-03 0,04770448 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 2,000 4,639E-03 0,04939163 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 4,663E-03 0,04942321 ! glutamate signaling pathway GO:0007215 41 22 1,000 4,663E-03 0,04920644 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,663E-03 0,04899157 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 4,663E-03 0,04877856 ! apoptotic nuclear changes GO:0030262 32 22 1,000 4,663E-03 0,0485674 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 4,663E-03 0,04835805 ! activation of JUN kinase activity GO:0007257 42 22 1,000 4,663E-03 0,04815051 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 4,663E-03 0,04794474 ! axon guidance GO:0007411 139 73 2,000 4,822E-03 0,04936917 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 5,009E-03 0,05106489 ! organelle localization GO:0051640 136 74 2,000 5,009E-03 0,05084943 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 5,092E-03 0,05147178 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 5,092E-03 0,05125642 ! gluconeogenesis GO:0006094 33 23 1,000 5,092E-03 0,05104285 ! visual behavior GO:0007632 42 23 1,000 5,092E-03 0,05083105 ! response to ethanol GO:0045471 46 23 1,000 5,092E-03 0,05062101 ! vesicle targeting GO:0006903 43 23 1,000 5,092E-03 0,05041269 ! sex determination GO:0007530 47 23 1,000 5,092E-03 0,05020608 ! synaptic vesicle transport GO:0048489 46 23 1,000 5,092E-03 0,05000116 ! negative regulation of catabolic process GO:0009895 50 23 1,000 5,092E-03 0,0497979 ! regulation of catabolic process GO:0009894 161 76 2,000 5,396E-03 0,05255725 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 5,538E-03 0,05372351 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 5,538E-03 0,05350775 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 1,000 5,538E-03 0,05329372 ! membrane depolarization GO:0051899 39 24 1,000 5,538E-03 0,05308139 ! pallium development GO:0021543 49 24 1,000 5,538E-03 0,05287075 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 6,001E-03 0,05706758 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 6,001E-03 0,05684291 ! vasculogenesis GO:0001570 46 25 1,000 6,001E-03 0,05661999 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 6,001E-03 0,05639882 ! somitogenesis GO:0001756 43 25 1,000 6,001E-03 0,05617937 ! activation of protein kinase activity GO:0032147 147 79 2,000 6,008E-03 0,05603143 ! regulation of peptidase activity GO:0052547 134 79 2,000 6,008E-03 0,05581509 ! pyruvate metabolic process GO:0006090 38 26 1,000 6,481E-03 0,05997649 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 6,481E-03 0,05974669 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 6,481E-03 0,05951865 ! cellular response to oxidative stress GO:0034599 39 26 1,000 6,481E-03 0,05929235 ! positive regulation of nuclear division GO:0051785 40 26 1,000 6,481E-03 0,05906775 GO:0045840|positive regulation of mitosis, ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 6,481E-03 0,05884486 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 6,979E-03 0,06312178 ! male gonad development GO:0008584 44 27 1,000 6,979E-03 0,06288537 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 6,979E-03 0,06265072 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 7,493E-03 0,0670157 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 8,023E-03 0,07149621 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 8,023E-03 0,07123239 ! cell fate determination GO:0001709 60 29 1,000 8,023E-03 0,0709705 ! regulation of cell adhesion GO:0030155 212 89 2,000 8,343E-03 0,07353189 ! cell junction assembly GO:0034329 78 30 1,000 8,57E-03 0,07525644 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 8,57E-03 0,07498278 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 8,57E-03 0,0747111 ! neurotransmitter secretion GO:0007269 48 30 1,000 8,57E-03 0,07444139 ! sex differentiation GO:0007548 145 90 2,000 8,602E-03 0,07444909 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 9,134E-03 0,07876593 ! GPI anchor biosynthetic process GO:0006506 53 31 1,000 9,134E-03 0,07848463 ! iron ion homeostasis GO:0055072 54 31 1,000 9,134E-03 0,07820532 ! positive regulation of immune effector process GO:0002699 67 31 1,000 9,134E-03 0,077928 ! regulation of defense response GO:0031347 149 92 2,000 9,134E-03 0,07765338 ! biogenic amine metabolic process GO:0006576 155 94 2,000 9,684E-03 0,08204322 ! regulation of T cell activation GO:0050863 158 94 2,000 9,684E-03 0,08175535 ! GPI anchor metabolic process GO:0006505 56 32 1,000 9,713E-03 0,08171288 ! spindle organization GO:0007051 46 32 1,000 9,713E-03 0,08142816 ! metanephros development GO:0001656 74 32 1,000 9,713E-03 0,08114543 ! response to mechanical stimulus GO:0009612 57 32 1,000 9,713E-03 0,08086465 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 9,713E-03 0,0805858 ! hexose biosynthetic process GO:0019319 48 32 1,000 9,713E-03 0,08030888 ! peripheral nervous system development GO:0007422 64 32 1,000 9,713E-03 0,08003385 ! hindbrain development GO:0030902 61 32 1,000 9,713E-03 0,07976069 ! post-embryonic development GO:0009791 69 33 1,000 0,01030858 0,08436205 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01030858 0,08407608 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01030858 0,08379204 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01091978 0,08846126 ! placenta development GO:0001890 53 34 1,000 0,01091978 0,08816441 ! odontogenesis GO:0042476 66 35 1,000 0,01154662 0,09291357 ! telencephalon development GO:0021537 68 35 1,000 0,01154662 0,09260386 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01154662 0,0922962 ! vesicle localization GO:0051648 64 35 1,000 0,01154662 0,09199059 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01218893 0,09678731 ! cell junction organization GO:0034330 86 36 1,000 0,01218893 0,09646893 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01218893 0,09615264 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01218893 0,09583842 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01218893 0,09552624 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01218893 0,09521609 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01218893 0,09490795 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01284656 0,09970586 ! meiosis I GO:0007127 65 37 1,000 0,01284656 0,09938526 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01284656 0,09906672 ! spermatid differentiation GO:0048515 66 37 1,000 0,01284656 0,09875021 ! phosphoinositide biosynthetic process GO:0046489 67 38 1,000 0,01351935 0,10359098 ! nucleus organization GO:0006997 67 38 1,000 0,01351935 0,10326212 ! learning GO:0007612 77 39 1,000 0,01420717 0,10817228 ! ear morphogenesis GO:0042471 60 39 1,000 0,01420717 0,10783104 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01420717 0,10749195 ! segmentation GO:0035282 67 39 1,000 0,01420717 0,10715499 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,01420717 0,10682013 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01490984 0,11175412 ! negative regulation of binding GO:0051100 72 40 1,000 0,01490984 0,11140706 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,01490984 0,11106214 ! maintenance of protein location GO:0045185 91 40 1,000 0,01490984 0,11071936 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,01562722 0,11568953 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,01562722 0,11533465 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01562722 0,11498195 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01562722 0,11463139 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01635917 0,11963573 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,01635917 0,11927319 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01635917 0,11891285 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,01635917 0,11855468 ! neuron migration GO:0001764 79 42 1,000 0,01635917 0,11819866 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01635917 0,11784477 ! neural tube development GO:0021915 77 43 1,000 0,01710552 0,12285339 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01710552 0,12248776 ! male sex differentiation GO:0046661 76 44 1,000 0,01786614 0,12755471 ! biopolymer methylation GO:0043414 84 44 1,000 0,01786614 0,12717733 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,01786614 0,12680218 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01786614 0,12642923 ! maintenance of location in cell GO:0051651 97 44 1,000 0,01786614 0,12605847 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01864088 0,13114022 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01864088 0,13075789 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,01864088 0,13037778 ! cell growth GO:0016049 84 45 1,000 0,01864088 0,12999987 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01942959 0,13510864 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,02023212 0,14028383 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,02023212 0,13988072 ! methylation GO:0032259 90 47 1,000 0,02023212 0,13947991 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,02104834 0,14469232 ! cellular component disassembly GO:0022411 86 48 1,000 0,02104834 0,14428009 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,02104834 0,14387021 ! activation of caspase activity GO:0006919 84 48 1,000 0,02104834 0,14346264 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02104834 0,14305738 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,02104834 0,1426544 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,0218781 0,14786156 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,0218781 0,14744738 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,0218781 0,14703552 ! neuromuscular process GO:0050905 99 50 1,000 0,02272126 0,15227675 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,02272126 0,15185376 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,02272126 0,15143312 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,02272126 0,15101479 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02302912 0,15263926 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02302912 0,15221992 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02302912 0,15180288 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02302912 0,15138812 ! neuron fate determination GO:0048664 7 5 0,000 0,02302912 0,15097562 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02302912 0,15056536 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02302912 0,15015732 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02302912 0,14975149 ! polyol transport GO:0015791 12 5 0,000 0,02302912 0,14934785 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02302912 0,14894637 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02302912 0,14854705 ! response to superoxide GO:0000303 10 5 0,000 0,02302912 0,14814987 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02302912 0,1477548 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02302912 0,14736184 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02302912 0,14697096 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02302912 0,14658215 ! female meiosis GO:0007143 7 5 0,000 0,02302912 0,14619539 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02302912 0,14581066 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02302912 0,14542796 ! cobalt ion transport GO:0006824 11 5 0,000 0,02302912 0,14504725 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02302912 0,14466854 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02302912 0,1442918 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02302912 0,14391702 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02302912 0,14354417 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02302912 0,14317326 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02302912 0,14280426 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02302912 0,14243715 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02302912 0,14207193 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02302912 0,14170857 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02302912 0,14134707 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02302912 0,14098741 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02302912 0,14062957 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02302912 0,14027355 ! negative chemotaxis GO:0050919 14 5 0,000 0,02302912 0,13991932 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02302912 0,13956688 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02302912 0,13921621 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02302912 0,1388673 ! behavioral response to pain GO:0048266 9 5 0,000 0,02302912 0,13852013 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02302912 0,13817469 ! Notch receptor processing GO:0007220 8 5 0,000 0,02302912 0,13783097 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02302912 0,13748896 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02302912 0,13714864 ! micturition GO:0060073 9 5 0,000 0,02302912 0,13681 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02302912 0,13647303 ! copulation GO:0007620 9 5 0,000 0,02302912 0,13613772 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02302912 0,13580405 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02302912 0,13547201 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02302912 0,13514159 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02302912 0,13481278 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02302912 0,13448556 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02302912 0,13415993 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02302912 0,13383587 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02302912 0,13351338 ! grooming behavior GO:0007625 6 5 0,000 0,02302912 0,13319243 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02302912 0,13287302 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02302912 0,13255515 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02302912 0,13223879 ! response to protozoan GO:0001562 10 5 0,000 0,02302912 0,13192393 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02302912 0,13161057 ! lymph vessel development GO:0001945 10 5 0,000 0,02302912 0,1312987 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02302912 0,1309883 ! endochondral ossification GO:0001958 16 5 0,000 0,02302912 0,13067937 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02302912 0,13037188 ! parathyroid gland development GO:0060017 13 5 0,000 0,02302912 0,13006585 ! anagen GO:0042640 6 5 0,000 0,02302912 0,12976124 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02302912 0,12945806 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02302912 0,1291563 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02302912 0,12885593 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02302912 0,12855696 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02302912 0,12825938 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02302912 0,12796317 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02302912 0,12766832 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02302912 0,12737483 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02302912 0,12708269 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02302912 0,12679188 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02302912 0,1265024 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02302912 0,12621424 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02302912 0,12592739 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02302912 0,12564184 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02302912 0,12535758 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02302912 0,12507461 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02302912 0,12479291 ! histidine catabolic process GO:0006548 6 5 0,000 0,02302912 0,12451247 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02302912 0,1242333 ! microvillus organization GO:0032528 7 5 0,000 0,02302912 0,12395537 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02302912 0,12367869 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02302912 0,12340323 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02302912 0,123129 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02302912 0,12285599 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02302912 0,12258418 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02302912 0,12231358 ! polyol catabolic process GO:0046174 7 5 0,000 0,02302912 0,12204417 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02302912 0,12177594 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02302912 0,12150888 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02302912 0,121243 ! muscle cell migration GO:0014812 8 5 0,000 0,02302912 0,12097828 ! mitochondrial fission GO:0000266 8 5 0,000 0,02302912 0,12071471 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02302912 0,12045228 ! mRNA transcription GO:0009299 9 5 0,000 0,02302912 0,120191 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02302912 0,11993085 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02302912 0,11967182 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02302912 0,1194139 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02302912 0,1191571 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02302912 0,1189014 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02302912 0,11864679 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02302912 0,11839327 ! response to food GO:0032094 6 5 0,000 0,02302912 0,11814083 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02302912 0,11788947 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02302912 0,11763917 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02302912 0,11738994 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02302912 0,11714176 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02302912 0,11689462 ! forebrain neuron development GO:0021884 13 5 0,000 0,02302912 0,11664853 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02302912 0,11640347 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02302912 0,11615944 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02302912 0,11591642 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02302912 0,11567443 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02302912 0,11543344 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02302912 0,11519345 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02302912 0,11495446 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02302912 0,11471646 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02302912 0,11447944 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02302912 0,1142434 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02302912 0,11400834 ! basic amino acid transport GO:0015802 11 5 0,000 0,02302912 0,11377423 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02302912 0,11354109 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02302912 0,1133089 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02302912 0,11307766 ! depyrimidination GO:0045008 10 5 0,000 0,02302912 0,11284735 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02302912 0,11261799 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02302912 0,11238956 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02302912 0,11216205 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02302912 0,11193546 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02302912 0,11170978 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02302912 0,11148501 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02302912 0,11126115 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02302912 0,11103818 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02302912 0,1108161 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02302912 0,11059491 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02302912 0,1103746 ! response to arsenic GO:0046685 10 5 0,000 0,02302912 0,11015517 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02302912 0,10993661 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02302912 0,10971891 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02302912 0,10950208 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02302912 0,1092861 ! response to cadmium ion GO:0046686 7 5 0,000 0,02302912 0,10907097 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02302912 0,10885668 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02302912 0,10864324 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02302912 0,10843063 ! decidualization GO:0046697 11 5 0,000 0,02302912 0,10821885 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02302912 0,1080079 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02302912 0,10779776 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02302912 0,10758845 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02302912 0,10737994 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02302912 0,10717225 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02302912 0,10696535 ! embryonic cleavage GO:0040016 6 5 0,000 0,02302912 0,10675925 ! peroxisome fission GO:0016559 5 5 0,000 0,02302912 0,10655394 ! histone demethylation GO:0016577 10 5 0,000 0,02302912 0,10634943 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02302912 0,10614569 ! mitotic recombination GO:0006312 9 5 0,000 0,02302912 0,10594274 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02302912 0,10574056 ! metaphase plate congression GO:0051310 7 5 0,000 0,02302912 0,10553914 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02302912 0,1053385 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02302912 0,10513862 ! enteric nervous system development GO:0048484 8 5 0,000 0,02302912 0,10493949 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02302912 0,10474112 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02302912 0,10454349 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02302912 0,10434661 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02302912 0,10415047 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02302912 0,10395507 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02302912 0,1037604 ! plasminogen activation GO:0031639 5 5 0,000 0,02302912 0,10356645 ! B cell homeostasis GO:0001782 13 5 0,000 0,02302912 0,10337323 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02302912 0,10318073 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02302912 0,10298894 ! metaphase GO:0051323 8 5 0,000 0,02302912 0,10279787 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02302912 0,1026075 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02302912 0,10241784 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02302912 0,10222888 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02302912 0,10204061 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02302912 0,10185304 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02302912 0,10166615 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02302912 0,10147995 ! response to redox state GO:0051775 5 5 0,000 0,02302912 0,10129443 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02302912 0,10110958 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02302912 0,10092541 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02302912 0,10074191 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02302912 0,10055908 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02302912 0,1003769 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02302912 0,10019539 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02302912 0,10001453 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02302912 0,09983433 ! striatum development GO:0021756 9 5 0,000 0,02302912 0,09965477 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02302912 0,09947585 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02302912 0,09929758 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02302912 0,09911995 ! glial cell migration GO:0008347 11 5 0,000 0,02302912 0,09894295 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02302912 0,09876658 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02302912 0,09859084 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02302912 0,09841572 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02302912 0,09824123 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02302912 0,09806735 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02302912 0,09789408 ! neuroprotection GO:0043526 6 5 0,000 0,02302912 0,09772143 ! neural plate development GO:0001840 8 5 0,000 0,02302912 0,09754939 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02302912 0,09737795 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02302912 0,09720711 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02302912 0,09703687 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02302912 0,09686722 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02302912 0,09669817 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02302912 0,09652971 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02302912 0,09636183 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02302912 0,09619453 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02302912 0,09602782 ! spindle assembly GO:0051225 6 5 0,000 0,02302912 0,09586168 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02302912 0,09569612 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02302912 0,09553112 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02302912 0,0953667 ! drug metabolic process GO:0017144 6 5 0,000 0,02302912 0,09520284 ! stem cell division GO:0017145 11 5 0,000 0,02302912 0,09503954 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02302912 0,0948768 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02302912 0,09471462 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02302912 0,09455299 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02302912 0,09439191 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,02357768 0,09647601 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,02357768 0,09631221 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,02357768 0,09614897 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,02357768 0,09598629 ! membrane fusion GO:0006944 110 52 1,000 0,02444721 0,09935811 ! synapse organization GO:0050808 85 52 1,000 0,02444721 0,09919055 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,02532973 0,1025982 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,02532973 0,10242577 ! response to UV GO:0009411 104 53 1,000 0,02532973 0,10225391 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,02622509 0,10569107 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,02713315 0,10916784 GO:0010952|positive regulation of peptidase activity, ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,02713315 0,10898559 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02757135 0,11056113 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02757135 0,11037717 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02757135 0,11019382 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02757135 0,11001108 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02757135 0,10982894 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02757135 0,1096474 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02757135 0,10946647 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02757135 0,10928613 ! response to oxygen radical GO:0000305 11 6 0,000 0,02757135 0,10910638 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02757135 0,10892722 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02757135 0,10874866 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02757135 0,10857067 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02757135 0,10839327 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02757135 0,10821644 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02757135 0,1080402 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02757135 0,10786452 ! forebrain regionalization GO:0021871 8 6 0,000 0,02757135 0,10768942 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02757135 0,10751488 ! male meiosis GO:0007140 7 6 0,000 0,02757135 0,10734091 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02757135 0,1071675 ! response to zinc ion GO:0010043 9 6 0,000 0,02757135 0,10699465 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02757135 0,10682235 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02757135 0,10665061 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02757135 0,10647942 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02757135 0,10630878 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02757135 0,10613869 ! malate metabolic process GO:0006108 11 6 0,000 0,02757135 0,10596914 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02757135 0,10580013 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02757135 0,10563166 ! protein refolding GO:0042026 15 6 0,000 0,02757135 0,10546372 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02757135 0,10529632 ! opsonization GO:0008228 8 6 0,000 0,02757135 0,10512945 ! mating behavior GO:0007617 7 6 0,000 0,02757135 0,1049631 ! neuron remodeling GO:0016322 15 6 0,000 0,02757135 0,10479728 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02757135 0,10463199 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02757135 0,10446721 ! equilibrioception GO:0050957 14 6 0,000 0,02757135 0,10430296 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02757135 0,10413922 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02757135 0,10397599 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02757135 0,10381327 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02757135 0,10365106 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02757135 0,10348936 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02757135 0,10332816 ! toxin metabolic process GO:0009404 11 6 0,000 0,02757135 0,10316746 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02757135 0,10300727 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02757135 0,10284757 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02757135 0,10268836 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02757135 0,10252964 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02757135 0,10237142 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02757135 0,10221368 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02757135 0,10205643 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02757135 0,10189966 ! thymic T cell selection GO:0045061 12 6 0,000 0,02757135 0,10174337 ! protein lipoylation GO:0009249 10 6 0,000 0,02757135 0,10158757 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02757135 0,10143223 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02757135 0,10127737 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02757135 0,10112299 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02757135 0,10096907 ! adenohypophysis development GO:0021984 10 6 0,000 0,02757135 0,10081562 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02757135 0,10066264 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02757135 0,10051012 ! hyperosmotic response GO:0006972 9 6 0,000 0,02757135 0,10035806 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02757135 0,10020647 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02757135 0,10005532 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02757135 0,09990464 ! urea metabolic process GO:0019627 7 6 0,000 0,02757135 0,09975441 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02757135 0,09960462 ! neutrophil activation GO:0042119 8 6 0,000 0,02757135 0,09945529 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02757135 0,09930641 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02757135 0,09915797 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02757135 0,09900997 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02757135 0,09886241 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02757135 0,0987153 ! neuron apoptosis GO:0051402 9 6 0,000 0,02757135 0,09856862 ! nucleoside salvage GO:0043174 9 6 0,000 0,02757135 0,09842237 GO:0006166|purine ribonucleoside salvage, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02757135 0,09827656 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02757135 0,09813118 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02757135 0,09798623 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02757135 0,09784171 ! carnitine transport GO:0015879 10 6 0,000 0,02757135 0,09769761 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02757135 0,09755394 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02757135 0,09741069 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02757135 0,09726786 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02757135 0,09712545 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02757135 0,09698345 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02757135 0,09684187 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02757135 0,0967007 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02757135 0,09655994 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02757135 0,09641959 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02757135 0,09627965 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02757135 0,09614012 ! neural nucleus development GO:0048857 14 6 0,000 0,02757135 0,09600098 ! response to UV-C GO:0010225 11 6 0,000 0,02757135 0,09586225 ! astrocyte development GO:0014002 15 6 0,000 0,02757135 0,09572392 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02757135 0,09558599 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02757135 0,09544846 ! interaction with symbiont GO:0051702 13 6 0,000 0,02757135 0,09531132 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02757135 0,09517458 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02757135 0,09503822 ! response to copper ion GO:0046688 10 6 0,000 0,02757135 0,09490226 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02757135 0,09476669 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02757135 0,0946315 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02757135 0,0944967 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02757135 0,09436228 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02757135 0,09422824 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02757135 0,09409458 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02757135 0,0939613 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02757135 0,0938284 ! hair follicle maturation GO:0048820 7 6 0,000 0,02757135 0,09369588 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02757135 0,09356372 ! Schwann cell development GO:0014044 15 6 0,000 0,02757135 0,09343194 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02757135 0,09330053 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02757135 0,09316949 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02757135 0,09303882 ! subpallium development GO:0021544 10 6 0,000 0,02757135 0,09290852 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02757135 0,09277857 ! histone ubiquitination GO:0016574 8 6 0,000 0,02757135 0,09264899 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02757135 0,09251978 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02757135 0,09239092 ! G2 phase GO:0051319 16 6 0,000 0,02757135 0,09226242 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02757135 0,09213428 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02757135 0,09200649 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02757135 0,09187906 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02757135 0,09175198 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02757135 0,09162525 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02757135 0,09149887 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02757135 0,09137284 ! receptor internalization GO:0031623 10 6 0,000 0,02757135 0,09124715 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02757135 0,09112181 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02757135 0,09099682 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02757135 0,09087216 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02757135 0,09074785 ! protein deubiquitination GO:0016579 14 6 0,000 0,02757135 0,09062388 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02757135 0,09050025 ! protein destabilization GO:0031648 9 6 0,000 0,02757135 0,09037695 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02757135 0,09025399 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02757135 0,09013136 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02757135 0,09000906 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02757135 0,0898871 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02757135 0,08976547 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02757135 0,08964416 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02757135 0,08952318 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02757135 0,08940253 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02757135 0,08928221 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02757135 0,0891622 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02757135 0,08904252 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02757135 0,08892316 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02757135 0,08880412 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02757135 0,0886854 ! catecholamine transport GO:0051937 9 6 0,000 0,02757135 0,088567 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02757135 0,08844891 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02757135 0,08833113 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02757135 0,08821367 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02757135 0,08809652 ! maternal placenta development GO:0001893 12 6 0,000 0,02757135 0,08797968 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02757135 0,08786315 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02757135 0,08774693 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02757135 0,08763102 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02757135 0,08751541 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02757135 0,08740011 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02757135 0,08728511 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02757135 0,08717041 ! regulation of actin filament length GO:0030832 105 56 1,000 0,02805379 0,08857929 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02805379 0,0884632 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,02805379 0,08834741 ! muscle fiber development GO:0048747 112 57 1,000 0,02898686 0,09116652 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02898686 0,0910475 ! maintenance of location GO:0051235 118 57 1,000 0,02898686 0,0909288 ! positive regulation of secretion GO:0051047 95 59 1,000 0,03088978 0,09677188 ! regulation of cellular component size GO:0032535 109 59 1,000 0,03088978 0,09664604 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,03088978 0,09652052 ! DNA catabolic process GO:0006308 86 59 1,000 0,03088978 0,09639533 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,03185936 0,09929224 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,03185936 0,09916379 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,03185936 0,09903567 ! kidney development GO:0001822 122 60 1,000 0,03185936 0,09890788 ! tRNA transcription GO:0009304 14 7 0,000 0,03209263 0,09950368 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03209263 0,09937562 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03209263 0,09924789 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03209263 0,09912049 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03209263 0,09899341 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03209263 0,09886666 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03209263 0,09874023 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03209263 0,09861412 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03209263 0,09848834 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03209263 0,09836288 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03209263 0,09823773 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03209263 0,09811291 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03209263 0,0979884 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03209263 0,09786421 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03209263 0,09774033 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03209263 0,09761676 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03209263 0,09749351 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03209263 0,09737057 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03209263 0,09724793 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03209263 0,09712561 ! glycolipid transport GO:0046836 10 7 0,000 0,03209263 0,09700359 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03209263 0,09688188 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03209263 0,09676048 ! neuron adhesion GO:0007158 12 7 0,000 0,03209263 0,09663937 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,03209263 0,09651857 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03209263 0,09639808 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03209263 0,09627788 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03209263 0,09615798 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03209263 0,09603838 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03209263 0,09591908 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03209263 0,09580007 ! mRNA stabilization GO:0048255 18 7 0,000 0,03209263 0,09568136 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03209263 0,09556294 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03209263 0,09544482 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03209263 0,09532699 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03209263 0,09520944 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03209263 0,09509219 ! lipoprotein transport GO:0042953 14 7 0,000 0,03209263 0,09497523 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03209263 0,09485855 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03209263 0,09474216 ! rhythmic behavior GO:0007622 15 7 0,000 0,03209263 0,09462605 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03209263 0,09451023 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03209263 0,09439469 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03209263 0,09427944 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03209263 0,09416446 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03209263 0,09404977 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03209263 0,09393535 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03209263 0,09382121 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03209263 0,09370735 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03209263 0,09359377 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03209263 0,09348046 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03209263 0,09336742 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03209263 0,09325466 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03209263 0,09314217 ! spinal cord patterning GO:0021511 13 7 0,000 0,03209263 0,09302995 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03209263 0,092918 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03209263 0,09280632 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03209263 0,09269491 ! adrenal gland development GO:0030325 17 7 0,000 0,03209263 0,09258376 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03209263 0,09247289 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03209263 0,09236227 ! ovulation GO:0030728 9 7 0,000 0,03209263 0,09225192 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03209263 0,09214184 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03209263 0,09203201 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03209263 0,09192245 ! microtubule nucleation GO:0007020 20 7 0,000 0,03209263 0,09181315 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03209263 0,09170411 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03209263 0,09159533 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03209263 0,0914868 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03209263 0,09137853 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03209263 0,09127052 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03209263 0,09116276 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03209263 0,09105526 ! galactose metabolic process GO:0006012 13 7 0,000 0,03209263 0,09094801 ! vesicle fusion GO:0006906 17 7 0,000 0,03209263 0,09084101 ! response to dietary excess GO:0002021 8 7 0,000 0,03209263 0,09073427 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03209263 0,09062777 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03209263 0,09052152 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03209263 0,09041553 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03209263 0,09030978 ! organ growth GO:0035265 15 7 0,000 0,03209263 0,09020428 ! purine salvage GO:0043101 10 7 0,000 0,03209263 0,09009902 ! nucleoside transport GO:0015858 8 7 0,000 0,03209263 0,08999401 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03209263 0,08988924 ! parturition GO:0007567 14 7 0,000 0,03209263 0,08978472 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03209263 0,08968044 ! rRNA modification GO:0000154 14 7 0,000 0,03209263 0,0895764 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03209263 0,08947261 ! spindle checkpoint GO:0031577 15 7 0,000 0,03209263 0,08936905 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03209263 0,08926573 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03209263 0,08916266 ! macrophage differentiation GO:0030225 11 7 0,000 0,03209263 0,08905981 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03209263 0,08895721 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03209263 0,08885484 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03209263 0,08875271 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03209263 0,08865081 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03209263 0,08854915 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03209263 0,08844772 ! fibrinolysis GO:0042730 10 7 0,000 0,03209263 0,08834652 ! eating behavior GO:0042755 7 7 0,000 0,03209263 0,08824555 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03209263 0,08814482 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03209263 0,08804431 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03209263 0,08794403 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03209263 0,08784398 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03209263 0,08774416 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03209263 0,08764456 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03209263 0,08754519 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03209263 0,08744605 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03209263 0,08734713 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03209263 0,08724843 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03209263 0,08714995 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03209263 0,0870517 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03209263 0,08695367 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03209263 0,08685586 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03209263 0,08675827 ! regulation of meiosis GO:0040020 12 7 0,000 0,03209263 0,0866609 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03209263 0,08656374 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03209263 0,08646681 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03209263 0,08637009 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03209263 0,08627359 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03209263 0,0861773 ! transcription termination GO:0006353 13 7 0,000 0,03209263 0,08608123 ! response to tumor cell GO:0002347 13 7 0,000 0,03209263 0,08598537 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03209263 0,08588972 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03209263 0,08579429 ! anaphase GO:0051322 17 7 0,000 0,03209263 0,08569907 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03209263 0,08560406 ! axonal fasciculation GO:0007413 18 7 0,000 0,03209263 0,08550926 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03209263 0,08541467 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03209263 0,08532029 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03209263 0,08522611 ! diuresis GO:0030146 12 7 0,000 0,03209263 0,08513215 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03209263 0,08503839 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03209263 0,08494484 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03209263 0,08485149 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03209263 0,08475835 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03209263 0,08466542 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03209263 0,08457268 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03209263 0,08448015 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03209263 0,08438782 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03209263 0,0842957 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03209263 0,08420377 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03209263 0,08411205 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03209263 0,08402052 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03209263 0,0839292 ! lymph node development GO:0048535 10 7 0,000 0,03209263 0,08383807 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03209263 0,08374714 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03209263 0,0836564 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03209263 0,08356587 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03209263 0,08347552 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03209263 0,08338538 ! adult feeding behavior GO:0008343 9 7 0,000 0,03209263 0,08329543 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03209263 0,08320567 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03209263 0,0831161 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03209263 0,08302673 ! muscle adaptation GO:0043500 14 7 0,000 0,03209263 0,08293755 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03209263 0,08284856 ! retina homeostasis GO:0001895 12 7 0,000 0,03209263 0,08275976 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03209263 0,08267116 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03209263 0,08258274 ! protein prenylation GO:0018342 18 7 0,000 0,03209263 0,08249451 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03209263 0,08240647 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03209263 0,08231861 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03209263 0,08223095 ! glycerophospholipid biosynthetic process GO:0046474 105 61 1,000 0,03284084 0,08405858 ! ear development GO:0043583 103 62 1,000 0,0338341 0,08650888 ! gonad development GO:0008406 98 62 1,000 0,0338341 0,08641704 ! regulation of mitosis GO:0007088 105 63 1,000 0,03483901 0,08888936 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,03483901 0,0887952 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,03483901 0,08870124 ! single fertilization GO:0007338 75 64 1,000 0,03585544 0,0911926 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03659303 0,09297024 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03659303 0,09287217 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,03659303 0,09277431 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03659303 0,09267665 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03659303 0,0925792 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03659303 0,09248195 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03659303 0,09238491 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03659303 0,09228807 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03659303 0,09219144 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03659303 0,092095 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03659303 0,09199877 ! meiotic prophase I GO:0007128 13 8 0,000 0,03659303 0,09190274 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03659303 0,0918069 ! oligopeptide transport GO:0006857 15 8 0,000 0,03659303 0,09171127 ! UTP metabolic process GO:0046051 8 8 0,000 0,03659303 0,09161584 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03659303 0,0915206 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03659303 0,09142557 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03659303 0,09133073 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03659303 0,09123608 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03659303 0,09114164 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03659303 0,09104738 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03659303 0,09095333 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03659303 0,09085946 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03659303 0,09076579 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03659303 0,09067232 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03659303 0,09057903 ! reflex GO:0060004 16 8 0,000 0,03659303 0,09048594 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03659303 0,09039304 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03659303 0,09030033 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03659303 0,09020781 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03659303 0,09011548 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03659303 0,09002333 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03659303 0,08993138 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03659303 0,08983961 ! pigment granule organization GO:0048753 16 8 0,000 0,03659303 0,08974803 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03659303 0,08965664 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03659303 0,08956543 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03659303 0,08947441 ! histidine metabolic process GO:0006547 16 8 0,000 0,03659303 0,08938357 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03659303 0,08929292 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03659303 0,08920245 ! glycine catabolic process GO:0006546 13 8 0,000 0,03659303 0,08911217 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03659303 0,08902206 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03659303 0,08893214 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,03659303 0,0888424 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03659303 0,08875284 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03659303 0,08866347 ! melanin metabolic process GO:0006582 15 8 0,000 0,03659303 0,08857427 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03659303 0,08848525 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03659303 0,08839641 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03659303 0,08830774 ! macrophage activation GO:0042116 12 8 0,000 0,03659303 0,08821926 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03659303 0,08813095 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03659303 0,08804282 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03659303 0,08795487 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03659303 0,08786709 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03659303 0,08777948 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03659303 0,08769205 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03659303 0,0876048 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03659303 0,08751771 ! osteoblast development GO:0002076 16 8 0,000 0,03659303 0,08743081 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03659303 0,08734407 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03659303 0,0872575 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03659303 0,08717111 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03659303 0,08708489 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03659303 0,08699883 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03659303 0,08691295 ! response to UV-B GO:0010224 16 8 0,000 0,03659303 0,08682724 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03659303 0,0867417 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03659303 0,08665632 ! intermediate filament organization GO:0045109 12 8 0,000 0,03659303 0,08657111 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03659303 0,08648607 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03659303 0,0864012 ! cellular extravasation GO:0045123 12 8 0,000 0,03659303 0,08631649 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03659303 0,08623195 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03659303 0,08614757 ! response to antibiotic GO:0046677 11 8 0,000 0,03659303 0,08606336 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03659303 0,08597932 ! DNA topological change GO:0006265 12 8 0,000 0,03659303 0,08589544 ! response to tropane GO:0014073 15 8 0,000 0,03659303 0,08581172 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03659303 0,08572816 ! melanosome transport GO:0032402 13 8 0,000 0,03659303 0,08564477 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03659303 0,08556154 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03659303 0,08547847 ! mast cell activation GO:0045576 14 8 0,000 0,03659303 0,08539556 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03659303 0,08531281 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03659303 0,08523022 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03659303 0,0851478 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03659303 0,08506553 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03659303 0,08498342 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03659303 0,08490147 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03659303 0,08481967 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03659303 0,08473804 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03659303 0,08465656 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03659303 0,08457524 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03659303 0,08449407 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03659303 0,08441306 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03659303 0,0843322 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03659303 0,0842515 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03659303 0,08417096 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03659303 0,08409056 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03659303 0,08401033 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03659303 0,08393024 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03659303 0,08385031 ! hormone catabolic process GO:0042447 17 8 0,000 0,03659303 0,08377052 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03659303 0,08369089 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03659303 0,08361142 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03659303 0,08353209 ! ATP catabolic process GO:0006200 11 8 0,000 0,03659303 0,08345291 ! blastocyst growth GO:0001832 19 8 0,000 0,03659303 0,08337388 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03659303 0,08329501 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03659303 0,08321628 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03659303 0,0831377 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03659303 0,08305927 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03659303 0,08298098 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03659303 0,08290284 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03659303 0,08282486 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03659303 0,08274701 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03659303 0,08266932 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03659303 0,08259176 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03659303 0,08251436 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03659303 0,0824371 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03659303 0,08235998 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03659303 0,08228301 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03659303 0,08220618 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03659303 0,0821295 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03659303 0,08205296 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,03688327 0,08262676 ! germ cell development GO:0007281 118 65 1,000 0,03688327 0,0825499 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,03897258 0,08714501 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,03897258 0,0870641 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,03897258 0,08698333 ! amino acid transport GO:0006865 125 68 1,000 0,04003383 0,08926913 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,04003383 0,08918647 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,04003383 0,08910397 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,04003383 0,08902162 ! axon extension GO:0048675 15 9 0,000 0,04107265 0,09124727 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04107265 0,09116309 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04107265 0,09107907 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04107265 0,09099521 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04107265 0,09091149 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04107265 0,09082794 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04107265 0,09074453 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04107265 0,09066128 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04107265 0,09057818 ! phosphate transport GO:0006817 19 9 0,000 0,04107265 0,09049523 ! reproductive behavior GO:0019098 19 9 0,000 0,04107265 0,09041244 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04107265 0,09032979 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04107265 0,0902473 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04107265 0,09016496 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04107265 0,09008277 ! GTP metabolic process GO:0046039 9 9 0,000 0,04107265 0,09000072 ! RNA methylation GO:0001510 15 9 0,000 0,04107265 0,08991883 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04107265 0,08983709 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04107265 0,08975549 ! artery development GO:0060840 24 9 0,000 0,04107265 0,08967404 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04107265 0,08959274 ! regulation of glycolysis GO:0006110 21 9 0,000 0,04107265 0,08951159 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04107265 0,08943058 ! chemosensory behavior GO:0007635 20 9 0,000 0,04107265 0,08934972 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04107265 0,08926901 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04107265 0,08918844 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04107265 0,08910802 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04107265 0,08902774 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04107265 0,08894761 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04107265 0,08886762 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04107265 0,08878778 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04107265 0,08870807 ! protein targeting to ER GO:0045047 22 9 0,000 0,04107265 0,08862852 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04107265 0,0885491 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04107265 0,08846983 ! T cell selection GO:0045058 23 9 0,000 0,04107265 0,08839069 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04107265 0,0883117 ! endosome organization GO:0007032 17 9 0,000 0,04107265 0,08823285 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04107265 0,08815414 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04107265 0,08807557 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04107265 0,08799715 ! mannose metabolic process GO:0006013 13 9 0,000 0,04107265 0,08791886 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04107265 0,08784071 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04107265 0,08776269 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04107265 0,08768482 ! receptor clustering GO:0043113 18 9 0,000 0,04107265 0,08760709 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04107265 0,08752949 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04107265 0,08745203 ! ruffle organization GO:0031529 15 9 0,000 0,04107265 0,08737471 ! retinol metabolic process GO:0042572 18 9 0,000 0,04107265 0,08729752 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04107265 0,08722047 ! behavioral fear response GO:0001662 22 9 0,000 0,04107265 0,08714356 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04107265 0,08706678 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04107265 0,08699014 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04107265 0,08691363 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,04107265 0,08683725 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04107265 0,08676101 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04107265 0,08668491 ! segment specification GO:0007379 13 9 0,000 0,04107265 0,08660893 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04107265 0,0865331 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04107265 0,08645739 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04107265 0,08638181 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04107265 0,08630637 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04107265 0,08623106 ! erythrocyte development GO:0048821 15 9 0,000 0,04107265 0,08615588 ! gas homeostasis GO:0033483 16 9 0,000 0,04107265 0,08608083 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04107265 0,08600591 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04107265 0,08593113 ! renal water homeostasis GO:0003091 14 9 0,000 0,04107265 0,08585647 ! postreplication repair GO:0006301 22 9 0,000 0,04107265 0,08578194 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04107265 0,08570754 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04107265 0,08563327 ! icosanoid secretion GO:0032309 15 9 0,000 0,04107265 0,08555913 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04107265 0,08548512 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04107265 0,08541123 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04107265 0,08533747 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04107265 0,08526384 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04107265 0,08519034 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04107265 0,08511696 ! sterol catabolic process GO:0016127 11 9 0,000 0,04107265 0,08504371 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04107265 0,08497059 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04107265 0,08489759 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04107265 0,08482472 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04107265 0,08475197 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04107265 0,08467934 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04107265 0,08460684 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04107265 0,08453447 ! purine base metabolic process GO:0006144 21 9 0,000 0,04107265 0,08446222 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04107265 0,08439009 ! pigment granule transport GO:0051904 17 9 0,000 0,04107265 0,08431808 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04107265 0,0842462 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04107265 0,08417444 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04107265 0,0841028 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04107265 0,08403129 ! mitochondrion localization GO:0051646 15 9 0,000 0,04107265 0,08395989 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,04110597 0,08395667 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,04110597 0,08388546 ! glycerolipid biosynthetic process GO:0045017 118 69 1,000 0,04110597 0,08381437 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,04328243 0,08817742 ! regulation of immune effector process GO:0002697 137 71 1,000 0,04328243 0,08810282 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,04438652 0,09027385 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,04438652 0,0901976 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,04438652 0,09012149 ! learning or memory GO:0007611 147 73 1,000 0,04550101 0,09230644 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,04550101 0,09222867 ! fertilization GO:0009566 90 73 1,000 0,04550101 0,09215104 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04553159 0,09213542 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,04553159 0,09205799 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04553159 0,0919807 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04553159 0,09190353 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04553159 0,0918265 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04553159 0,09174959 ! synapsis GO:0007129 13 10 0,000 0,04553159 0,09167281 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04553159 0,09159616 ! N-glycan processing GO:0006491 20 10 0,000 0,04553159 0,09151964 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04553159 0,09144325 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04553159 0,09136698 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04553159 0,09129084 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04553159 0,09121483 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04553159 0,09113894 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04553159 0,09106318 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04553159 0,09098755 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04553159 0,09091204 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04553159 0,09083666 ! androgen metabolic process GO:0008209 17 10 0,000 0,04553159 0,0907614 ! phospholipid efflux GO:0033700 16 10 0,000 0,04553159 0,09068627 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04553159 0,09061126 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04553159 0,09053637 ! lung alveolus development GO:0048286 26 10 0,000 0,04553159 0,09046161 ! pathogenesis GO:0009405 13 10 0,000 0,04553159 0,09038697 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04553159 0,09031246 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04553159 0,09023806 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04553159 0,09016379 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04553159 0,09008965 ! endoderm development GO:0007492 16 10 0,000 0,04553159 0,09001562 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04553159 0,08994172 ! arginine catabolic process GO:0006527 13 10 0,000 0,04553159 0,08986793 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04553159 0,08979427 ! proline metabolic process GO:0006560 13 10 0,000 0,04553159 0,08972073 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04553159 0,08964731 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04553159 0,08957401 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04553159 0,08950082 ! V(D)J recombination GO:0033151 28 10 0,000 0,04553159 0,08942776 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04553159 0,08935482 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04553159 0,089282 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04553159 0,08920929 ! B cell proliferation GO:0042100 18 10 0,000 0,04553159 0,0891367 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04553159 0,08906424 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04553159 0,08899188 ! multicellular organism growth GO:0035264 18 10 0,000 0,04553159 0,08891965 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04553159 0,08884753 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04553159 0,08877553 ! epithelial cell development GO:0002064 20 10 0,000 0,04553159 0,08870365 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04553159 0,08863188 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04553159 0,08856023 ! macroautophagy GO:0016236 17 10 0,000 0,04553159 0,0884887 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04553159 0,08841728 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04553159 0,08834598 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04553159 0,08827479 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04553159 0,08820371 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04553159 0,08813275 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04553159 0,0880619 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04553159 0,08799117 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04553159 0,08792055 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04553159 0,08785005 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04553159 0,08777965 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04553159 0,08770937 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04553159 0,08763921 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04553159 0,08756915 ! response to dsRNA GO:0043331 20 10 0,000 0,04553159 0,08749921 ! DNA ligation GO:0006266 19 10 0,000 0,04553159 0,08742938 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04553159 0,08735966 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04553159 0,08729005 ! melanosome localization GO:0032400 16 10 0,000 0,04553159 0,08722055 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04553159 0,08715116 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04553159 0,08708188 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04553159 0,08701272 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04553159 0,08694366 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04553159 0,08687471 ! mRNA cleavage GO:0006379 17 10 0,000 0,04553159 0,08680587 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04553159 0,08673714 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04553159 0,08666852 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04553159 0,08660001 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04553159 0,0865316 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04553159 0,08646331 ! salivary gland development GO:0007431 27 10 0,000 0,04553159 0,08639512 ! prophase GO:0051324 15 10 0,000 0,04553159 0,08632704 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04553159 0,08625906 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04553159 0,0861912 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04553159 0,08612343 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04553159 0,08605578 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04553159 0,08598823 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04553159 0,08592079 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04553159 0,08585346 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04553159 0,08578622 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04553159 0,0857191 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04553159 0,08565208 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04553159 0,08558516 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04553159 0,08551835 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04553159 0,08545165 ! oocyte development GO:0048599 17 10 0,000 0,04553159 0,08538504 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04553159 0,08531854 ! blastocyst formation GO:0001825 17 10 0,000 0,04553159 0,08525215 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04553159 0,08518585 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04553159 0,08511967 ! activation of innate immune response GO:0002218 12 10 0,000 0,04553159 0,08505358 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04553159 0,08498759 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04553159 0,08492171 ! response to nicotine GO:0035094 20 10 0,000 0,04553159 0,08485593 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04553159 0,08479025 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04553159 0,08472468 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04553159 0,0846592 ! localization within membrane GO:0051668 20 10 0,000 0,04553159 0,08459383 ! neurotransmitter transport GO:0006836 123 74 1,000 0,04662579 0,08655992 ! meiosis GO:0007126 121 74 1,000 0,04662579 0,08649318 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 1,000 0,04662579 0,08642655 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,04662579 0,08636002 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,04776075 0,08839412 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,04776075 0,08832618 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,04776075 0,08825834 ! meiotic cell cycle GO:0051321 122 75 1,000 0,04776075 0,0881906 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,04890575 0,09023561 ! respiratory burst GO:0045730 17 11 0,000 0,04996995 0,0921285 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04996995 0,09205796 ! neuron fate specification GO:0048665 17 11 0,000 0,04996995 0,09198752 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04996995 0,0919172 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04996995 0,09184698 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04996995 0,09177687 ! thyroid gland development GO:0030878 26 11 0,000 0,04996995 0,09170686 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,04996995 0,09163696 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04996995 0,09156717 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04996995 0,09149748 ! response to pain GO:0048265 24 11 0,000 0,04996995 0,0914279 ! T cell proliferation GO:0042098 26 11 0,000 0,04996995 0,09135843 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04996995 0,09128906 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04996995 0,0912198 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04996995 0,09115064 ! bone resorption GO:0045453 16 11 0,000 0,04996995 0,09108159 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,04996995 0,09101264 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04996995 0,09094379 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04996995 0,09087505 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04996995 0,09080641 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04996995 0,09073788 ! syncytium formation GO:0006949 18 11 0,000 0,04996995 0,09066945 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04996995 0,09060113 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04996995 0,0905329 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04996995 0,09046478 ! lipid digestion GO:0044241 18 11 0,000 0,04996995 0,09039676 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04996995 0,09032885 ! UV protection GO:0009650 19 11 0,000 0,04996995 0,09026103 ! adult heart development GO:0007512 14 11 0,000 0,04996995 0,09019332 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04996995 0,09012571 ! temperature homeostasis GO:0001659 17 11 0,000 0,04996995 0,0900582 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04996995 0,08999079 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04996995 0,08992348 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04996995 0,08985627 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04996995 0,08978917 ! regulation of organ growth GO:0046620 13 11 0,000 0,04996995 0,08972216 ! pigment granule localization GO:0051875 20 11 0,000 0,04996995 0,08965525 ! vasoconstriction GO:0042310 18 11 0,000 0,04996995 0,08958845 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04996995 0,08952174 ! embryonic axis specification GO:0000578 18 11 0,000 0,04996995 0,08945513 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04996995 0,08938862 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04996995 0,08932221 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04996995 0,0892559 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04996995 0,08918968 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04996995 0,08912357 ! zymogen activation GO:0031638 15 11 0,000 0,04996995 0,08905755 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04996995 0,08899163 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04996995 0,08892581 ! nucleosome positioning GO:0016584 15 11 0,000 0,04996995 0,08886008 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04996995 0,08879446 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04996995 0,08872892 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04996995 0,08866349 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04996995 0,08859815 ! acid secretion GO:0046717 18 11 0,000 0,04996995 0,08853291 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04996995 0,08846777 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04996995 0,08840272 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04996995 0,08833776 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04996995 0,0882729 ! oocyte differentiation GO:0009994 18 11 0,000 0,04996995 0,08820814 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04996995 0,08814347 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04996995 0,0880789 ! cholesterol efflux GO:0033344 19 11 0,000 0,04996995 0,08801442 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04996995 0,08795003 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04996995 0,08788574 ! germ cell migration GO:0008354 25 11 0,000 0,04996995 0,08782154 ! embryonic gut development GO:0048566 15 11 0,000 0,04996995 0,08775744 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04996995 0,08769343 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04996995 0,08762951 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04996995 0,08756569 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04996995 0,08750196 ! defense response to fungus GO:0050832 13 11 0,000 0,04996995 0,08743832 ! developmental induction GO:0031128 19 11 0,000 0,04996995 0,08737478 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04996995 0,08731132 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04996995 0,08724796 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04996995 0,08718469 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04996995 0,08712152 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04996995 0,08705843 ! nucleus localization GO:0051647 19 11 0,000 0,04996995 0,08699544 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,0500607 0,08709041 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,0500607 0,08702748 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,0500607 0,08696464 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,05122546 0,08892385 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,05239993 0,09089707 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05438781 0,09427743 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05438781 0,09420956 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05438781 0,09414178 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05438781 0,0940741 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05438781 0,09400652 ! virus-host interaction GO:0019048 29 12 0,000 0,05438781 0,09393903 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,05438781 0,09387165 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05438781 0,09380435 ! cartilage condensation GO:0001502 20 12 0,000 0,05438781 0,09373716 ! mating GO:0007618 17 12 0,000 0,05438781 0,09367006 ! protein complex disassembly GO:0043241 27 12 0,000 0,05438781 0,09360306 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05438781 0,09353615 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05438781 0,09346934 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,05438781 0,09340262 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05438781 0,093336 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05438781 0,09326948 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05438781 0,09320304 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05438781 0,09313671 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05438781 0,09307046 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05438781 0,09300432 ! drug transport GO:0015893 16 12 0,000 0,05438781 0,09293826 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05438781 0,0928723 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05438781 0,09280644 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05438781 0,09274066 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05438781 0,09267498 ! focal adhesion formation GO:0048041 35 12 0,000 0,05438781 0,09260939 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05438781 0,0925439 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05438781 0,0924785 ! forebrain cell migration GO:0021885 21 12 0,000 0,05438781 0,09241319 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05438781 0,09234797 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05438781 0,09228284 ! entry into host cell GO:0030260 32 12 0,000 0,05438781 0,09221781 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05438781 0,09215287 ! monoamine transport GO:0015844 18 12 0,000 0,05438781 0,09208802 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05438781 0,09202326 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05438781 0,09195859 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05438781 0,09189401 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05438781 0,09182953 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05438781 0,09176513 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05438781 0,09170082 ! protein homotetramerization GO:0051289 21 12 0,000 0,05438781 0,09163661 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05438781 0,09157248 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05438781 0,09150844 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05438781 0,0914445 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05438781 0,09138064 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05438781 0,09131687 ! cranial nerve development GO:0021545 20 12 0,000 0,05438781 0,09125319 ! fucose catabolic process GO:0019317 22 12 0,000 0,05438781 0,0911896 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05438781 0,0911261 ! histone acetylation GO:0016573 26 12 0,000 0,05438781 0,09106268 ! histone methylation GO:0016571 26 12 0,000 0,05438781 0,09099936 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05438781 0,09093612 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05438781 0,09087297 ! gland morphogenesis GO:0022612 29 12 0,000 0,05438781 0,09080991 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05438781 0,09074693 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05438781 0,09068404 ! T cell homeostasis GO:0043029 25 12 0,000 0,05438781 0,09062124 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05438781 0,09055853 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05438781 0,0904959 ! spleen development GO:0048536 22 12 0,000 0,05438781 0,09043336 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05438781 0,09037091 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05438781 0,09030854 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05438781 0,09024626 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05438781 0,09018406 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05438781 0,09012195 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05438781 0,09005993 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05438781 0,08999799 ! response to cold GO:0009409 17 12 0,000 0,05438781 0,08993613 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05438781 0,08987436 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,05477753 0,09045624 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,05477753 0,0903942 ! response to nutrient GO:0007584 125 82 1,000 0,05598044 0,09231593 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,05598044 0,0922527 ! regulation of ligase activity GO:0051340 142 84 1,000 0,05841392 0,09619704 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05878528 0,09674239 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05878528 0,09667627 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05878528 0,09661023 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05878528 0,09654428 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05878528 0,09647843 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05878528 0,09641266 ! lipid localization GO:0010876 28 13 0,000 0,05878528 0,09634699 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,05878528 0,0962814 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05878528 0,0962159 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05878528 0,09615049 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05878528 0,09608517 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05878528 0,09601994 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05878528 0,0959548 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05878528 0,09588975 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05878528 0,09582478 ! methionine metabolic process GO:0006555 27 13 0,000 0,05878528 0,0957599 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05878528 0,09569511 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05878528 0,09563041 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05878528 0,09556579 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05878528 0,09550127 ! response to X-ray GO:0010165 25 13 0,000 0,05878528 0,09543683 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05878528 0,09537247 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05878528 0,0953082 ! exocrine system development GO:0035272 32 13 0,000 0,05878528 0,09524402 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05878528 0,09517993 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05878528 0,09511592 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05878528 0,095052 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05878528 0,09498816 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05878528 0,09492441 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05878528 0,09486075 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05878528 0,09479717 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05878528 0,09473367 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05878528 0,09467027 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05878528 0,09460694 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05878528 0,0945437 ! ribosome assembly GO:0042255 17 13 0,000 0,05878528 0,09448055 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,05878528 0,09441747 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05878528 0,09435449 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05878528 0,09429158 ! chromatin silencing GO:0006342 26 13 0,000 0,05878528 0,09422876 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05878528 0,09416603 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05878528 0,09410338 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05878528 0,09404081 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05878528 0,09397832 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05878528 0,09391592 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05878528 0,0938536 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05878528 0,09379136 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05878528 0,09372921 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05878528 0,09366714 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05878528 0,09360515 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05878528 0,09354324 ! embryonic placenta development GO:0001892 23 13 0,000 0,05878528 0,09348141 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05878528 0,09341967 ! insulin secretion GO:0030073 23 13 0,000 0,05878528 0,093358 ! actin filament polymerization GO:0030041 24 13 0,000 0,05878528 0,09329642 ! acrosome reaction GO:0007340 18 13 0,000 0,05878528 0,09323492 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,05964426 0,09453497 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,05964426 0,09447274 GO:0002696|positive regulation of leukocyte activation, ! amine transport GO:0015837 155 86 1,000 0,06088353 0,09637222 ! regulation of protein transport GO:0051223 154 87 1,000 0,06213162 0,09828315 GO:0070201|regulation of establishment of protein localization, ! rRNA transcription GO:0009303 25 14 0,000 0,06316244 0,09984811 ! lactation GO:0007595 26 14 0,000 0,06316244 0,09978255 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,06316244 0,09971708 ! reproductive cellular process GO:0048610 20 14 0,000 0,06316244 0,09965169 ! tRNA modification GO:0006400 20 14 0,000 0,06316244 0,09958639 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06316244 0,09952117 ! regulation of S phase GO:0033261 23 14 0,000 0,06316244 0,09945604 ! water transport GO:0006833 21 14 0,000 0,06316244 0,09939099 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06316244 0,09932603 ! non-recombinational repair GO:0000726 25 14 0,000 0,06316244 0,09926115 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06316244 0,09919636 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06316244 0,09913165 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06316244 0,09906703 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06316244 0,09900249 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06316244 0,09893804 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06316244 0,09887367 ! palate development GO:0060021 31 14 0,000 0,06316244 0,09880938 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06316244 0,09874518 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06316244 0,09868106 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06316244 0,09861702 ! arginine metabolic process GO:0006525 17 14 0,000 0,06316244 0,09855306 ! regulation of heart rate GO:0002027 24 14 0,000 0,06316244 0,09848919 ! organic alcohol transport GO:0015850 29 14 0,000 0,06316244 0,09842541 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06316244 0,0983617 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06316244 0,09829808 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06316244 0,09823454 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06316244 0,09817108 ! L-amino acid transport GO:0015807 30 14 0,000 0,06316244 0,0981077 ! bone mineralization GO:0030282 17 14 0,000 0,06316244 0,0980444 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06316244 0,09798119 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06316244 0,09791806 ! cerebellum development GO:0021549 21 14 0,000 0,06316244 0,09785501 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06316244 0,09779204 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06316244 0,09772915 ! response to gamma radiation GO:0010332 28 14 0,000 0,06316244 0,09766634 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06316244 0,09760361 ! cofactor transport GO:0051181 26 14 0,000 0,06316244 0,09754097 ! NADP metabolic process GO:0006739 24 14 0,000 0,06316244 0,0974784 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06316244 0,09741591 ! intestinal absorption GO:0050892 25 14 0,000 0,06316244 0,09735351 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06316244 0,09729118 ! oxygen transport GO:0015671 21 14 0,000 0,06316244 0,09722894 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06316244 0,09716677 ! male genitalia development GO:0030539 24 14 0,000 0,06316244 0,09710468 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06316244 0,09704267 ! regulation of axon extension GO:0030516 37 14 0,000 0,06316244 0,09698074 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06316244 0,09691889 ! regulation of DNA binding GO:0051101 155 88 1,000 0,06338842 0,09720366 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,06465382 0,09908095 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,06592772 0,10096887 ! superoxide anion generation GO:0042554 20 15 0,000 0,06751939 0,10334074 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06751939 0,10327505 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06751939 0,10320943 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06751939 0,1031439 ! copper ion transport GO:0006825 20 15 0,000 0,06751939 0,10307846 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06751939 0,10301309 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06751939 0,10294781 ! sulfate transport GO:0008272 23 15 0,000 0,06751939 0,10288261 ! response to cAMP GO:0051591 22 15 0,000 0,06751939 0,1028175 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06751939 0,10275246 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06751939 0,10268751 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06751939 0,10262265 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06751939 0,10255786 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06751939 0,10249315 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06751939 0,10242853 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06751939 0,10236399 ! pituitary gland development GO:0021983 29 15 0,000 0,06751939 0,10229953 ! vesicle coating GO:0006901 33 15 0,000 0,06751939 0,10223515 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06751939 0,10217085 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,06751939 0,10210663 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,06751939 0,10204249 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06751939 0,10197844 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06751939 0,10191446 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06751939 0,10185056 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06751939 0,10178675 ! histone deacetylation GO:0016575 20 15 0,000 0,06751939 0,10172301 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06751939 0,10165935 ! tissue regeneration GO:0042246 26 15 0,000 0,06751939 0,10159578 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06751939 0,10153228 ! water homeostasis GO:0030104 27 15 0,000 0,06751939 0,10146886 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06751939 0,10140552 ! muscle maintenance GO:0046716 26 15 0,000 0,06751939 0,10134226 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06751939 0,10127908 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06751939 0,10121598 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06751939 0,10115296 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06751939 0,10109001 ! cell killing GO:0001906 29 15 0,000 0,06751939 0,10102714 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06751939 0,10096435 ! detection of bacterium GO:0016045 18 15 0,000 0,06751939 0,10090164 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06751939 0,10083901 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06751939 0,10077646 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06751939 0,10071398 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06751939 0,10065158 ! peptide hormone processing GO:0016486 23 15 0,000 0,06751939 0,10058926 ! phospholipid biosynthetic process GO:0008654 167 92 1,000 0,0685006 0,1019879 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,06979937 0,10385731 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,06979937 0,10379313 ! female pregnancy GO:0007565 164 94 1,000 0,07110622 0,10567113 ! transcription initiation GO:0006352 153 94 1,000 0,07110622 0,1056059 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07185622 0,10665396 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07185622 0,1065882 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,07185622 0,10652253 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07185622 0,10645693 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07185622 0,10639142 ! bone remodeling GO:0046849 27 16 0,000 0,07185622 0,10632599 ! filopodium assembly GO:0046847 32 16 0,000 0,07185622 0,10626064 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07185622 0,10619537 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07185622 0,10613018 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07185622 0,10606507 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07185622 0,10600004 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,07185622 0,10593509 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07185622 0,10587022 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07185622 0,10580542 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07185622 0,10574071 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07185622 0,10567608 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07185622 0,10561152 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07185622 0,10554705 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07185622 0,10548265 ! response to osmotic stress GO:0006970 25 16 0,000 0,07185622 0,10541833 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,07185622 0,10535409 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,07185622 0,10528993 ! fructose metabolic process GO:0006000 25 16 0,000 0,07185622 0,10522584 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07185622 0,10516184 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07185622 0,10509791 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07185622 0,10503406 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07185622 0,10497029 ! negative regulation of immune response GO:0050777 35 16 0,000 0,07185622 0,10490659 ! axon cargo transport GO:0008088 43 16 0,000 0,07185622 0,10484297 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07185622 0,10477943 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07185622 0,10471597 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,07185622 0,10465258 ! neuron recognition GO:0008038 35 16 0,000 0,07185622 0,10458927 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07185622 0,10452604 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07185622 0,10446288 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07185622 0,1043998 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07185622 0,10433679 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,07185622 0,10427386 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07185622 0,10421101 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07185622 0,10414823 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07185622 0,10408553 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07185622 0,1040229 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07185622 0,10396035 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07185622 0,10389787 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07185622 0,10383547 ! defense response to virus GO:0051607 37 16 0,000 0,07185622 0,10377315 ! mRNA transport GO:0051028 169 96 1,000 0,07374376 0,1064352 ! positive regulation of immune response GO:0050778 156 96 1,000 0,07374376 0,10637139 ! detection of stimulus GO:0051606 151 96 1,000 0,07374376 0,10630766 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,07507425 0,10816087 ! protein ubiquitination GO:0016567 217 97 1,000 0,07507425 0,10809614 ! regulation of protein localization GO:0032880 176 97 1,000 0,07507425 0,10803149 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07617302 0,1095471 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07617302 0,10948166 ! metencephalon development GO:0022037 30 17 0,000 0,07617302 0,10941629 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07617302 0,10935101 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07617302 0,1092858 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07617302 0,10922068 ! signal complex assembly GO:0007172 41 17 0,000 0,07617302 0,10915562 ! endothelial cell migration GO:0043542 28 17 0,000 0,07617302 0,10909065 ! inositol metabolic process GO:0006020 28 17 0,000 0,07617302 0,10902575 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07617302 0,10896094 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07617302 0,10889619 ! glial cell development GO:0021782 27 17 0,000 0,07617302 0,10883153 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07617302 0,10876694 ! adult walking behavior GO:0007628 33 17 0,000 0,07617302 0,10870243 ! heart looping GO:0001947 30 17 0,000 0,07617302 0,10863799 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07617302 0,10857363 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07617302 0,10850935 ! myoblast differentiation GO:0045445 45 17 0,000 0,07617302 0,10844514 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07617302 0,10838101 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,07617302 0,10831696 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07617302 0,10825298 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07617302 0,10818908 ! glycine metabolic process GO:0006544 28 17 0,000 0,07617302 0,10812525 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,07617302 0,10806149 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07617302 0,10799782 ! NAD metabolic process GO:0019674 29 17 0,000 0,07617302 0,10793421 ! membrane budding GO:0006900 37 17 0,000 0,07617302 0,10787069 ! DNA integration GO:0015074 29 17 0,000 0,07617302 0,10780723 ! regulation of protein binding GO:0043393 33 17 0,000 0,07617302 0,10774385 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07617302 0,10768055 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07617302 0,10761732 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07617302 0,10755416 ! genitalia development GO:0048806 30 17 0,000 0,07617302 0,10749108 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07617302 0,10742807 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07617302 0,10736514 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07617302 0,10730228 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07617302 0,10723949 ! steroid catabolic process GO:0006706 31 17 0,000 0,07617302 0,10717678 ! gas transport GO:0015669 25 17 0,000 0,07617302 0,10711414 ! organic cation transport GO:0015695 31 17 0,000 0,07617302 0,10705157 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07617302 0,10698908 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07617302 0,10692666 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07617302 0,10686431 ! microspike assembly GO:0030035 36 17 0,000 0,07617302 0,10680204 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07617302 0,10673983 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07617302 0,1066777 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,07775817 0,1088343 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,0791114 0,11066397 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08046989 0,11249887 ! neuron maturation GO:0042551 42 18 0,000 0,08046989 0,11243354 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08046989 0,11236829 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08046989 0,11230311 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,08046989 0,11223801 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08046989 0,11217298 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08046989 0,11210803 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08046989 0,11204315 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08046989 0,11197835 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08046989 0,11191362 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08046989 0,11184897 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08046989 0,11178439 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08046989 0,11171989 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08046989 0,11165546 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08046989 0,1115911 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,08046989 0,11152682 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,08046989 0,11146261 ! response to fungus GO:0009620 21 18 0,000 0,08046989 0,11139848 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08046989 0,11133442 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08046989 0,11127044 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08046989 0,11120653 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08046989 0,11114269 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08046989 0,11107892 ! vitamin transport GO:0051180 27 18 0,000 0,08046989 0,11101523 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08046989 0,11095161 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08046989 0,11088807 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08046989 0,11082459 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08046989 0,11076119 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,08046989 0,11069786 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08046989 0,11063461 ! nerve development GO:0021675 28 18 0,000 0,08046989 0,11057142 ! protein secretion GO:0009306 39 19 0,000 0,08474692 0,1163819 ! positive regulation of translation GO:0045727 30 19 0,000 0,08474692 0,11631551 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08474692 0,11624919 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08474692 0,11618296 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,08474692 0,11611679 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08474692 0,1160507 ! lipid phosphorylation GO:0046834 35 19 0,000 0,08474692 0,11598469 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08474692 0,11591875 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08474692 0,11585289 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08474692 0,1157871 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,08474692 0,11572139 ! cerebral cortex development GO:0021987 36 19 0,000 0,08474692 0,11565575 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,08474692 0,11559019 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,08474692 0,1155247 ! actin filament bundle formation GO:0051017 42 19 0,000 0,08474692 0,11545928 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08474692 0,11539394 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,08474692 0,11532867 ! peptide cross-linking GO:0018149 37 19 0,000 0,08474692 0,11526348 ! protein export from nucleus GO:0006611 36 19 0,000 0,08474692 0,11519835 ! heart process GO:0003015 30 19 0,000 0,08474692 0,11513331 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08474692 0,11506833 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08474692 0,11500343 ! G1 phase GO:0051318 40 19 0,000 0,08474692 0,11493861 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08474692 0,11487385 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08474692 0,11480917 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08474692 0,11474456 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08474692 0,11468003 ! cilium assembly GO:0042384 37 19 0,000 0,08474692 0,11461556 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08474692 0,11455117 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08900419 0,12023812 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08900419 0,12017064 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08900419 0,12010325 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08900419 0,12003592 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08900419 0,11996868 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,08900419 0,11990151 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,08900419 0,11983441 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08900419 0,11976739 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08900419 0,11970044 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08900419 0,11963357 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08900419 0,11956677 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08900419 0,11950005 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08900419 0,1194334 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,08900419 0,11936683 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08900419 0,11930033 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08900419 0,1192339 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08900419 0,11916755 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,08900419 0,11910127 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,08900419 0,11903507 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08900419 0,11896894 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08900419 0,11890288 ! body fluid secretion GO:0007589 31 20 0,000 0,08900419 0,1188369 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08900419 0,11877099 ! peptide secretion GO:0002790 35 20 0,000 0,08900419 0,11870515 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08900419 0,11863938 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08900419 0,11857369 ! sensory perception of pain GO:0019233 30 20 0,000 0,08900419 0,11850807 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08900419 0,11844253 ! diencephalon development GO:0021536 34 20 0,000 0,08900419 0,11837705 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08900419 0,11831165 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08900419 0,11824632 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08900419 0,11818106 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,08900419 0,11811588 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08900419 0,11805077 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08900419 0,11798572 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08900419 0,11792075 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08900419 0,11785586 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08900419 0,11779103 ! actin filament-based movement GO:0030048 43 20 0,000 0,08900419 0,11772627 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,08900419 0,11766159 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08900419 0,11759697 ! negative regulation of translation GO:0017148 29 20 0,000 0,08900419 0,11753243 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08900419 0,11746796 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,08900419 0,11740356 ! regulation of cell killing GO:0031341 42 21 0,000 0,09324181 0,12292591 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,09324181 0,12285859 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09324181 0,12279134 ! hormone secretion GO:0046879 38 21 0,000 0,09324181 0,12272417 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09324181 0,12265707 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,09324181 0,12259005 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,09324181 0,12252309 ! ovarian follicle development GO:0001541 35 21 0,000 0,09324181 0,12245621 ! smooth muscle contraction GO:0006939 46 21 0,000 0,09324181 0,12238941 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09324181 0,12232267 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09324181 0,12225601 ! cell aging GO:0007569 44 21 0,000 0,09324181 0,12218942 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,09324181 0,12212291 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,09324181 0,12205647 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,09324181 0,12199009 ! cytolysis GO:0019835 24 21 0,000 0,09324181 0,1219238 ! vasodilation GO:0042311 39 21 0,000 0,09324181 0,12185757 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09324181 0,12179141 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,09324181 0,12172533 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09324181 0,12165932 ! oogenesis GO:0048477 36 21 0,000 0,09324181 0,12159338 ! collagen fibril organization GO:0030199 59 21 0,000 0,09324181 0,12152751 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,09324181 0,12146171 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09324181 0,12139599 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09324181 0,12133033 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,09324181 0,12126475 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,09324181 0,12119923 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09324181 0,12113379 ! collagen catabolic process GO:0030574 28 21 0,000 0,09324181 0,12106842 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09324181 0,12100312 ! gut development GO:0048565 39 21 0,000 0,09324181 0,12093789 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,09745985 0,12634073 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09745985 0,12627269 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09745985 0,12620473 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09745985 0,12613684 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09745985 0,12606903 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09745985 0,12600128 ! regeneration GO:0031099 41 22 0,000 0,09745985 0,12593361 ! keratinization GO:0031424 28 22 0,000 0,09745985 0,12586602 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,09745985 0,12579849 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,09745985 0,12573104 ! sensory perception of taste GO:0050909 28 22 0,000 0,09745985 0,12566366 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,09745985 0,12559635 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09745985 0,12552912 ! vacuolar transport GO:0007034 36 22 0,000 0,09745985 0,12546195 ! lysosome organization GO:0007040 41 22 0,000 0,09745985 0,12539486 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09745985 0,12532784 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09745985 0,12526089 ! fucose metabolic process GO:0006004 39 22 0,000 0,09745985 0,12519401 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09745985 0,12512721 ! ureteric bud development GO:0001657 43 22 0,000 0,09745985 0,12506047 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09745985 0,12499381 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,09745985 0,12492722 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,09745985 0,1248607 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09745985 0,12479425 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09745985 0,12472787 ! sarcomere organization GO:0045214 30 22 0,000 0,09745985 0,12466156 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,09745985 0,12459532 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09745985 0,12452915 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09745985 0,12446305 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,09745985 0,12439702 ! protein stabilization GO:0050821 39 22 0,000 0,09745985 0,12433107 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,1016584 0,12961851 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,1016584 0,12954985 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1016584 0,12948127 ! viral genome replication GO:0019079 41 23 0,000 0,1016584 0,12941276 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1016584 0,12934433 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1016584 0,12927596 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1016584 0,12920767 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1016584 0,12913945 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,1016584 0,1290713 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1016584 0,12900323 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,1016584 0,12893522 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,1016584 0,12886729 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,1016584 0,12879943 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,1016584 0,12873164 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1016584 0,12866392 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1016584 0,12859628 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1016584 0,1285287 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,1016584 0,1284612 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,1016584 0,12839376 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1016584 0,1283264 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1016584 0,12825911 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1016584 0,12819189 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1016584 0,12812474 ! fatty acid transport GO:0015908 44 23 0,000 0,1016584 0,12805765 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1016584 0,12799064 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1016584 0,1279237 ! hormone transport GO:0009914 40 23 0,000 0,1016584 0,12785683 ! cell-cell recognition GO:0009988 25 23 0,000 0,1016584 0,12779003 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1016584 0,1277233 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1016584 0,12765664 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1016584 0,12759005 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1016584 0,12752353 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,10583757 0,13269682 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,10583757 0,13262771 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10583757 0,13255866 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10583757 0,1324897 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10583757 0,1324208 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10583757 0,13235197 ! vesicle docking GO:0048278 47 24 0,000 0,10583757 0,13228322 ! spinal cord development GO:0021510 47 24 0,000 0,10583757 0,13221454 ! vacuole organization GO:0007033 43 24 0,000 0,10583757 0,13214592 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10583757 0,13207738 ! digestive system process GO:0022600 39 24 0,000 0,10583757 0,13200891 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10583757 0,13194052 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10583757 0,13187219 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10583757 0,13180393 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,10583757 0,13173574 ! pentose metabolic process GO:0019321 35 24 0,000 0,10583757 0,13166763 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,10583757 0,13159958 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,10583757 0,13153161 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10583757 0,1314637 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10583757 0,13139587 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10583757 0,1313281 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10583757 0,13126041 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10583757 0,13119278 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10583757 0,13112523 ! regulation of amine transport GO:0051952 40 24 0,000 0,10583757 0,13105774 ! protein tetramerization GO:0051262 52 24 0,000 0,10583757 0,13099033 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10999743 0,1360688 ! phototransduction GO:0007602 33 25 0,000 0,10999743 0,13599888 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10999743 0,13592903 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,10999743 0,13585925 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10999743 0,13578955 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,10999743 0,13571991 ! receptor metabolic process GO:0043112 46 25 0,000 0,10999743 0,13565035 ! chromosome condensation GO:0030261 45 25 0,000 0,10999743 0,13558085 ! response to starvation GO:0042594 42 25 0,000 0,10999743 0,13551143 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10999743 0,13544208 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,10999743 0,1353728 ! neural crest cell development GO:0014032 54 25 0,000 0,10999743 0,13530359 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10999743 0,13523445 ! negative regulation of cell development GO:0010721 73 25 0,000 0,10999743 0,13516538 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10999743 0,13509639 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10999743 0,13502746 ! interaction with host GO:0051701 62 25 0,000 0,10999743 0,1349586 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10999743 0,13488982 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,10999743 0,1348211 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10999743 0,13475246 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10999743 0,13468388 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10999743 0,13461537 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10999743 0,13454694 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10999743 0,13447857 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,10999743 0,13441027 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10999743 0,13434204 ! telomere organization GO:0032200 43 25 0,000 0,10999743 0,13427388 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10999743 0,13420579 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10999743 0,13413777 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11413808 0,13911663 ! embryonic pattern specification GO:0009880 44 26 0,000 0,11413808 0,13904619 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,11413808 0,13897582 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,11413808 0,13890552 ! initiation of viral infection GO:0019059 57 26 0,000 0,11413808 0,1388353 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,11413808 0,13876514 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11413808 0,13869506 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,11413808 0,13862505 ! molting cycle process GO:0022404 50 26 0,000 0,11413808 0,13855511 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,11413808 0,13848524 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,11413808 0,13841543 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11413808 0,1383457 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,11413808 0,13827604 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,11413808 0,13820645 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,11413808 0,13813693 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,11413808 0,13806748 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,11413808 0,1379981 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11413808 0,13792879 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11413808 0,13785955 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,11413808 0,13779038 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,11413808 0,13772127 ! blastocyst development GO:0001824 49 26 0,000 0,11413808 0,13765224 ! leukocyte proliferation GO:0070661 52 26 0,000 0,11413808 0,13758328 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,11413808 0,13751438 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,1182596 0,14240871 ! neuron fate commitment GO:0048663 48 27 0,000 0,1182596 0,14233747 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,1182596 0,1422663 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,1182596 0,1421952 ! iron ion transport GO:0006826 59 27 0,000 0,1182596 0,14212418 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,1182596 0,14205322 ! protein amino acid acylation GO:0043543 55 27 0,000 0,1182596 0,14198233 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,1182596 0,14191152 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,1182596 0,14184078 ! fat cell differentiation GO:0045444 50 27 0,000 0,1182596 0,1417701 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,1182596 0,1416995 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,1182596 0,14162897 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,1182596 0,14155851 ! autophagy GO:0006914 41 27 0,000 0,1182596 0,14148811 ! response to toxin GO:0009636 47 27 0,000 0,1182596 0,14141779 ! primary neural tube formation GO:0014020 51 27 0,000 0,1182596 0,14134754 ! base-excision repair GO:0006284 41 27 0,000 0,1182596 0,14127736 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,1182596 0,14120725 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,1182596 0,1411372 ! glutathione metabolic process GO:0006749 39 27 0,000 0,1182596 0,14106723 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,1182596 0,14099732 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,1182596 0,14092749 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,1182596 0,14085772 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,12236208 0,14567203 ! circadian rhythm GO:0007623 50 28 0,000 0,12236208 0,14559998 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,12236208 0,14552801 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,12236208 0,14545611 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,12236208 0,14538428 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,12236208 0,14531252 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,12236208 0,14524083 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,12236208 0,14516922 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,12236208 0,14509767 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,12236208 0,14502619 ! synaptogenesis GO:0007416 42 28 0,000 0,12236208 0,14495479 ! lipid oxidation GO:0034440 43 28 0,000 0,12236208 0,14488345 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,12236208 0,14481218 ! translational initiation GO:0006413 65 29 0,000 0,12644561 0,14957136 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,12644561 0,14949786 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12644561 0,14942443 ! regulation of pH GO:0006885 43 29 0,000 0,12644561 0,14935107 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12644561 0,14927779 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12644561 0,14920458 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12644561 0,14913144 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,12644561 0,14905837 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12644561 0,14898538 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 0,000 0,12644561 0,14891245 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12644561 0,1488396 ! detection of light stimulus GO:0009583 38 29 0,000 0,12644561 0,14876682 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,12644561 0,14869411 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,12644561 0,14862147 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,12644561 0,1485489 ! tissue homeostasis GO:0001894 48 29 0,000 0,12644561 0,1484764 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,12644561 0,14840397 ! zinc ion transport GO:0006829 45 30 0,000 0,13051027 0,15309982 ! membrane docking GO:0022406 61 30 0,000 0,13051027 0,15302521 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,13051027 0,15295067 ! regulation of innate immune response GO:0045088 51 30 0,000 0,13051027 0,1528762 ! acute-phase response GO:0006953 49 30 0,000 0,13051027 0,15280181 ! myofibril assembly GO:0030239 47 30 0,000 0,13051027 0,15272749 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,13051027 0,15265324 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,13051027 0,15257907 ! phospholipid transport GO:0015914 51 30 0,000 0,13051027 0,15250496 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,13051027 0,15243093 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,13051027 0,15235697 ! eye morphogenesis GO:0048592 60 30 0,000 0,13051027 0,15228309 ! regulation of B cell activation GO:0050864 50 30 0,000 0,13051027 0,15220927 ! response to heat GO:0009408 50 30 0,000 0,13051027 0,15213552 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,13455616 0,15677585 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,13455616 0,15669996 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,13455616 0,15662415 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,13455616 0,15654842 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,13455616 0,15647275 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,13455616 0,15639716 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,13455616 0,15632164 ! ovulation cycle process GO:0022602 49 31 0,000 0,13455616 0,1562462 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,13455616 0,15617083 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,13455616 0,15609553 ! peptide transport GO:0015833 55 31 0,000 0,13455616 0,1560203 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,13455616 0,15594515 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,13455616 0,15587006 ! natural killer cell activation GO:0030101 45 31 0,000 0,13455616 0,15579505 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,13455616 0,15572012 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,13455616 0,15564525 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,13455616 0,15557046 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,13455616 0,15549574 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,13858335 0,16007276 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,13858335 0,15999595 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13858335 0,15991921 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,13858335 0,15984255 ! cholesterol transport GO:0030301 56 32 0,000 0,13858335 0,15976596 ! spliceosome assembly GO:0000245 67 32 0,000 0,13858335 0,15968944 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13858335 0,159613 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13858335 0,15953663 ! response to ionizing radiation GO:0010212 65 32 0,000 0,13858335 0,15946033 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,13858335 0,15938411 ! muscle cell development GO:0055001 49 32 0,000 0,13858335 0,15930795 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,13858335 0,15923188 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13858335 0,15915587 ! ovulation cycle GO:0042698 51 32 0,000 0,13858335 0,15907994 ! BMP signaling pathway GO:0030509 64 32 0,000 0,13858335 0,15900408 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,13858335 0,15892829 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13858335 0,15885257 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,13858335 0,15877693 ! gene silencing GO:0016458 65 32 0,000 0,13858335 0,15870136 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,14259194 0,16321418 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,14259194 0,16313657 ! protein targeting to membrane GO:0006612 68 33 0,000 0,14259194 0,16305903 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,14259194 0,16298157 ! ceramide metabolic process GO:0006672 64 33 0,000 0,14259194 0,16290418 ! cell fate specification GO:0001708 52 33 0,000 0,14259194 0,16282687 ! sterol transport GO:0015918 57 33 0,000 0,14259194 0,16274962 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,14259194 0,16267246 ! adult locomotory behavior GO:0008344 59 33 0,000 0,14259194 0,16259536 ! glial cell differentiation GO:0010001 63 34 0,000 0,14658201 0,16706599 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,14658201 0,16698689 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,14658201 0,16690786 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,14658201 0,16682891 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,14658201 0,16675003 ! mismatch repair GO:0006298 46 34 0,000 0,14658201 0,16667122 ! spermatid development GO:0007286 63 34 0,000 0,14658201 0,16659249 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,14658201 0,16651384 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,14658201 0,16643526 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,14658201 0,16635675 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,15055364 0,17078361 ! negative regulation of secretion GO:0051048 63 35 0,000 0,15055364 0,17070313 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,15055364 0,17062273 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,15055364 0,17054239 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,15055364 0,17046214 ! female gonad development GO:0008585 58 35 0,000 0,15055364 0,17038196 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,15055364 0,17030186 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 0,000 0,15055364 0,17022183 ! cytokine production GO:0001816 59 35 0,000 0,15055364 0,17014187 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,15055364 0,17006199 ! neural tube formation GO:0001841 67 35 0,000 0,15055364 0,16998219 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,15450691 0,1743638 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! sphingoid metabolic process GO:0046519 70 36 0,000 0,15450691 0,17428206 ! positive regulation of cell development GO:0010720 80 36 0,000 0,15450691 0,17420039 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,15450691 0,1741188 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,15450691 0,17403728 ! aerobic respiration GO:0009060 55 36 0,000 0,15450691 0,17395584 ! embryonic organ development GO:0048568 57 36 0,000 0,15450691 0,17387448 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15844192 0,17821939 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,15844192 0,17813611 ! actomyosin structure organization GO:0031032 62 37 0,000 0,15844192 0,1780529 ! organic anion transport GO:0015711 68 37 0,000 0,15844192 0,17796978 ! tissue remodeling GO:0048771 76 37 0,000 0,15844192 0,17788673 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,15844192 0,17780376 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,15844192 0,17772087 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,15844192 0,17763805 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15844192 0,17755532 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,15844192 0,17747266 ! glycogen metabolic process GO:0005977 61 37 0,000 0,15844192 0,17739007 ! pigment metabolic process GO:0042440 80 37 0,000 0,15844192 0,17730757 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,15844192 0,17722513 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,16235875 0,18152191 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,16235875 0,1814376 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,16235875 0,18135337 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,16235875 0,18126921 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,16235875 0,18118513 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,16235875 0,18110114 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,16235875 0,18101721 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,16235875 0,18093337 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,16235875 0,18084961 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,16235875 0,18076592 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,16235875 0,18068231 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,16235875 0,18059877 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,16235875 0,18051532 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,16235875 0,18043194 ! glucan metabolic process GO:0044042 62 38 0,000 0,16235875 0,18034864 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,16625747 0,18459413 ! organic ether metabolic process GO:0018904 55 39 0,000 0,16625747 0,18450899 ! ion transmembrane transport GO:0034220 66 39 0,000 0,16625747 0,18442392 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,16625747 0,18433893 ! RNA modification GO:0009451 57 39 0,000 0,16625747 0,18425402 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,16625747 0,18416919 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,17013818 0,18838126 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,17013818 0,1882946 ! feeding behavior GO:0007631 59 40 0,000 0,17013818 0,18820803 ! mesenchymal cell development GO:0014031 87 40 0,000 0,17013818 0,18812154 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,17013818 0,18803513 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,17400096 0,19221593 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,17400096 0,19212772 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,17400096 0,19203959 ! gliogenesis GO:0042063 88 41 0,000 0,17400096 0,19195154 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,17400096 0,19186357 ! T cell differentiation GO:0030217 81 41 0,000 0,17400096 0,19177568 ! female gamete generation GO:0007292 61 41 0,000 0,17400096 0,19168787 ! polyol metabolic process GO:0019751 66 41 0,000 0,17400096 0,19160014 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,17784588 0,19574437 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,17784588 0,19565486 ! regulation of tube size GO:0035150 71 42 0,000 0,17784588 0,19556544 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,17784588 0,1954761 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,17784588 0,19538684 ! regulation of protein secretion GO:0050708 71 42 0,000 0,17784588 0,19529767 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,18167303 0,19940936 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,18167303 0,19931843 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,18167303 0,19922758 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,18167303 0,19913682 ! glucose transport GO:0015758 65 43 0,000 0,18167303 0,19904613 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,18167303 0,19895554 ! striated muscle contraction GO:0006941 77 43 0,000 0,18167303 0,19886502 ! phagocytosis GO:0006909 90 43 0,000 0,18167303 0,19877458 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,18167303 0,19868423 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,18548249 0,20275824 ! hexose transport GO:0008645 67 44 0,000 0,18548249 0,20266616 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,18548249 0,20257416 ! double-strand break repair GO:0006302 81 44 0,000 0,18548249 0,20248225 ! B cell differentiation GO:0030183 107 44 0,000 0,18548249 0,20239042 ! developmental growth GO:0048589 82 44 0,000 0,18548249 0,20229868 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,18927435 0,20634077 ! glycolysis GO:0006096 65 45 0,000 0,18927435 0,20624732 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,18927435 0,20615395 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,18927435 0,20606067 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,18927435 0,20596747 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,18927435 0,20587436 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,19304868 0,20988482 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,19304868 0,20979002 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,19304868 0,20969531 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,19304868 0,20960068 ! response to insulin stimulus GO:0032868 95 46 0,000 0,19304868 0,20950614 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,19304868 0,20941168 ! response to calcium ion GO:0051592 81 47 0,000 0,19680556 0,21339079 ! endosome transport GO:0016197 108 47 0,000 0,19680556 0,21329467 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,19680556 0,21319864 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,19680556 0,21310269 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,19680556 0,21300682 ! protein homooligomerization GO:0051260 76 47 0,000 0,19680556 0,21291105 ! mitochondrial transport GO:0006839 82 48 0,000 0,20054507 0,21685908 ! Notch signaling pathway GO:0007219 96 48 0,000 0,20054507 0,21676165 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,20054507 0,21666432 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,20054507 0,21656708 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,20054507 0,21646992 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,2042673 0,22038885 ! regulation of ion transport GO:0043269 77 49 0,000 0,2042673 0,22029006 ! peptide metabolic process GO:0006518 76 49 0,000 0,2042673 0,22019136 ! response to temperature stimulus GO:0009266 76 49 0,000 0,2042673 0,22009276 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2042673 0,21999424 ! endocrine system development GO:0035270 104 49 0,000 0,2042673 0,21989581 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,2042673 0,21979746 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,2042673 0,21969921 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,20797232 0,22358419 ! regulation of ossification GO:0030278 117 50 0,000 0,20797232 0,22348433 ! inner ear development GO:0048839 79 50 0,000 0,20797232 0,22338456 ! histone modification GO:0016570 91 50 0,000 0,20797232 0,22328488 ! positive regulation of binding GO:0051099 78 51 0,000 0,21166021 0,22714294 ! viral infectious cycle GO:0019058 99 51 0,000 0,21166021 0,22704168 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,21166021 0,2269405 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,21166021 0,22683941 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,21166021 0,22673841 ! excretion GO:0007588 83 51 0,000 0,21166021 0,22663751 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,21166021 0,22653669 ! chromatin remodeling GO:0006338 109 51 0,000 0,21166021 0,22643596 ! vesicle organization GO:0016050 107 51 0,000 0,21166021 0,22633532 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,21166021 0,22623477 ! covalent chromatin modification GO:0016569 101 52 0,000 0,21533106 0,23005618 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,21533106 0,22995407 ! amino acid activation GO:0043038 92 52 0,000 0,21533106 0,22985205 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! RNA catabolic process GO:0006401 93 53 0,000 0,21898493 0,23364867 ! regulation of translational initiation GO:0006446 82 53 0,000 0,21898493 0,2335451 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,21898493 0,23344162 ! cell maturation GO:0048469 100 53 0,000 0,21898493 0,23333824 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,21898493 0,23323495 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,21898493 0,23313174 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,22262191 0,23689885 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,22262191 0,23679412 ! cell recognition GO:0008037 85 54 0,000 0,22262191 0,23668949 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,22262191 0,23658494 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,22262191 0,23648049 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,22262191 0,23637613 ! chloride transport GO:0006821 90 55 0,000 0,22624207 0,24011399 ! glucose catabolic process GO:0006007 82 55 0,000 0,22624207 0,24000812 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,22624207 0,23990234 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,22624207 0,23979666 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,22624207 0,23969107 ! aging GO:0007568 103 55 0,000 0,22624207 0,23958557 ! heart morphogenesis GO:0003007 97 55 0,000 0,22624207 0,23948017 ! RNA elongation GO:0006354 79 55 0,000 0,22624207 0,23937485 ! nuclear export GO:0051168 97 55 0,000 0,22624207 0,23926964 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,22624207 0,23916451 ! sensory perception of smell GO:0007608 80 56 0,000 0,22984549 0,24286704 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,22984549 0,24276043 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,22984549 0,24265391 ! regulation of DNA replication GO:0006275 101 56 0,000 0,22984549 0,24254748 ! proton transport GO:0015992 94 56 0,000 0,22984549 0,24244115 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,23343225 0,24611657 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,23343225 0,24600876 ! lipid modification GO:0030258 97 57 0,000 0,23343225 0,24590105 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,23343225 0,24579344 ! hydrogen transport GO:0006818 97 58 0,000 0,23700243 0,2494435 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,23700243 0,24933443 ! regulation of endocytosis GO:0030100 91 58 0,000 0,23700243 0,24922546 ! adult behavior GO:0030534 99 58 0,000 0,23700243 0,24911658 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,23700243 0,24900779 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,2405561 0,25263115 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,2405561 0,25252093 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,24409333 0,25612235 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,2476142 0,25970348 ! tRNA processing GO:0008033 89 61 0,000 0,2476142 0,25959032 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2476142 0,25947725 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,2476142 0,25936429 ! viral reproductive process GO:0022415 126 62 0,000 0,2511188 0,26292072 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,2511188 0,26280636 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,25460718 0,26634125 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,25460718 0,2662255 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,25460718 0,26610985 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,25807943 0,26962184 ! cell redox homeostasis GO:0045454 102 64 0,000 0,25807943 0,26950482 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,25807943 0,2693879 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,25807943 0,26927108 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 0,000 0,25807943 0,26915436 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,26153562 0,27264068 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,26153562 0,27252261 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,26497582 0,27598781 ! actin filament organization GO:0007015 148 66 0,000 0,26497582 0,27586838 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,26497582 0,27574906 ! extracellular matrix organization GO:0030198 133 66 0,000 0,26497582 0,27562985 ! secondary metabolic process GO:0019748 116 66 0,000 0,26497582 0,27551073 ! developmental maturation GO:0021700 116 66 0,000 0,26497582 0,27539172 ! cell projection assembly GO:0030031 120 66 0,000 0,26497582 0,27527281 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,26840012 0,27870983 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,26840012 0,27858959 ! lung development GO:0030324 144 67 0,000 0,26840012 0,27846946 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,26840012 0,27834943 ! hexose catabolic process GO:0019320 104 67 0,000 0,26840012 0,2782295 ! adaptive immune response GO:0002250 119 67 0,000 0,26840012 0,27810968 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,26840012 0,27798996 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,27180857 0,28139906 ! viral reproduction GO:0016032 134 68 0,000 0,27180857 0,28127803 ! regulation of lipase activity GO:0060191 130 68 0,000 0,27180857 0,2811571 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,27180857 0,28103628 ! negative regulation of cell size GO:0045792 134 69 0,000 0,27520125 0,28442191 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,27520125 0,28429979 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,27520125 0,28417777 ! antigen processing and presentation GO:0019882 104 69 0,000 0,27520125 0,28405586 ! respiratory tube development GO:0030323 150 70 0,000 0,27857824 0,2874182 ! amine catabolic process GO:0009310 117 71 0,000 0,28193961 0,29076155 ! humoral immune response GO:0006959 109 71 0,000 0,28193961 0,29063698 ! B cell activation GO:0042113 160 71 0,000 0,28193961 0,29051251 ! acute inflammatory response GO:0002526 113 72 0,000 0,28528543 0,29383422 ! carbohydrate transport GO:0008643 110 72 0,000 0,28528543 0,29370849 ! respiratory system development GO:0060541 153 72 0,000 0,28528543 0,29358287 ! regulation of blood pressure GO:0008217 125 73 0,000 0,28861577 0,29688309 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,2919307 0,30016464 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,2919307 0,30003642 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,2919307 0,29990831 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,29523029 0,30316863 ! rhythmic process GO:0048511 128 75 0,000 0,29523029 0,30303929 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,29523029 0,30291006 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,29851462 0,30614927 ! defense response to bacterium GO:0042742 89 76 0,000 0,29851462 0,30601882 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,29851462 0,30588849 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,29851462 0,30575827 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,30178375 0,3089752 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,30503776 0,3121739 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,30503776 0,31204117 ! protein oligomerization GO:0051259 139 78 0,000 0,30503776 0,31190856 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,3082767 0,31508655 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,3082767 0,31495276 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,31150066 0,31811146 ! response to metal ion GO:0010038 140 80 0,000 0,31150066 0,31797649 ! muscle cell differentiation GO:0042692 159 80 0,000 0,31150066 0,31784164 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,31150066 0,31770691 ! protein import into nucleus GO:0006606 158 80 0,000 0,31150066 0,31757228 ! inorganic anion transport GO:0015698 138 80 0,000 0,31150066 0,31743778 ! T cell activation GO:0042110 168 81 0,000 0,3147097 0,3205722 ! response to hypoxia GO:0001666 171 81 0,000 0,3147097 0,32043654 ! digestion GO:0007586 112 81 0,000 0,3147097 0,32030099 ! nuclear import GO:0051170 161 81 0,000 0,3147097 0,32016556 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,3147097 0,32003024 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,31790389 0,32314185 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,31790389 0,32300539 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,31790389 0,32286904 ! response to oxygen levels GO:0070482 176 83 0,000 0,32108329 0,32596051 ! regulation of lyase activity GO:0051339 160 83 0,000 0,32108329 0,32582303 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,32424799 0,32889572 ! negative regulation of growth GO:0045926 155 84 0,000 0,32424799 0,32875712 ! response to unfolded protein GO:0006986 131 85 0,000 0,32739803 0,33181115 ! nucleosome assembly GO:0006334 122 85 0,000 0,32739803 0,33167144 ! amine biosynthetic process GO:0009309 138 86 0,000 0,3305335 0,3347069 ! response to inorganic substance GO:0010035 153 86 0,000 0,3305335 0,33456609 ! chromatin assembly GO:0031497 124 86 0,000 0,3305335 0,33442539 ! tube morphogenesis GO:0035239 176 86 0,000 0,3305335 0,33428482 ! alcohol catabolic process GO:0046164 130 86 0,000 0,3305335 0,33414437 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,33365445 0,33715775 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,33365445 0,3370162 ! protein localization in nucleus GO:0034504 176 87 0,000 0,33365445 0,33687478 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,33676095 0,33986865 ! cellular defense response GO:0006968 114 89 0,000 0,33985308 0,3428455 ! ossification GO:0001503 188 90 0,000 0,34293089 0,34580542 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,34293089 0,34566055 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,34293089 0,3455158 ! bone development GO:0060348 189 91 0,000 0,34599446 0,34845654 ! sterol metabolic process GO:0016125 152 91 0,000 0,34599446 0,34831074 ! response to protein stimulus GO:0051789 149 91 0,000 0,34599446 0,34816506 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,34599446 0,34801951 ! nucleosome organization GO:0034728 138 92 0,000 0,34904384 0,35094003 ! vitamin metabolic process GO:0006766 139 92 0,000 0,34904384 0,35079343 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,35207911 0,35369617 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,35207911 0,35354855 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,35810755 0,35945213 ! leukocyte differentiation GO:0002521 202 96 0,000 0,36110085 0,36230552 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,36110085 0,3621545 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,36408029 0,36499049 ! hormone metabolic process GO:0042445 157 97 0,000 0,36408029 0,36483848 ! response to virus GO:0009615 160 98 0,000 0,36704594 0,36765718 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,36704594 0,36750418 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,36704594 0,3673513 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,36999786 0,3701517 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,36999786 0,36999786