pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6595-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cell motion GO:0051270 79 79 4,000 1,339E-06 2,468E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 2,449E-06 2,257E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 2,549E-06 1,566E-03 ! positive regulation of endocytosis GO:0045807 12 12 2,000 3,261E-06 1,502E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 4,232E-06 1,56E-03 ! protein tetramerization GO:0051262 13 13 2,000 4,232E-06 1,3E-03 ! ossification GO:0001503 50 49 3,000 6,459E-06 1,7E-03 GO:0060348|bone development, ! regulation of fibroblast proliferation GO:0048145 17 17 2,000 9,996E-06 2,303E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 1,198E-05 2,452E-03 ! regulation of cell migration GO:0030334 71 71 3,000 2,857E-05 5,266E-03 ! glucose homeostasis GO:0042593 24 24 2,000 2,941E-05 4,928E-03 GO:0033500|carbohydrate homeostasis, ! positive regulation of hydrolase activity GO:0051345 72 72 3,000 3,02E-05 4,639E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 3,337E-05 4,731E-03 ! regulation of endocytosis GO:0030100 25 25 2,000 3,337E-05 4,393E-03 ! regulation of locomotion GO:0040012 79 79 3,000 4,361E-05 5,358E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 4,73E-05 5,448E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 5,267E-05 5,71E-03 ! response to UV GO:0009411 29 29 2,000 5,267E-05 5,393E-03 ! regulation of ossification GO:0030278 30 30 2,000 5,842E-05 5,667E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 6,436E-05 5,93E-03 ! prostate gland development GO:0030850 5 5 1,000 6,436E-05 5,648E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 6,436E-05 5,391E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 6,436E-05 5,157E-03 ! positive regulation of phagocytosis GO:0050766 5 5 1,000 6,436E-05 4,942E-03 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 1,000 6,436E-05 4,744E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 6,436E-05 4,562E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 6,436E-05 4,393E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 6,458E-05 4,251E-03 ! negative regulation of cell motion GO:0051271 31 31 2,000 6,458E-05 4,104E-03 ! regulation of vesicle-mediated transport GO:0060627 33 32 2,000 7,114E-05 4,37E-03 ! negative regulation of cell cycle GO:0045786 92 91 3,000 7,606E-05 4,522E-03 ! regulation of bone remodeling GO:0046850 34 34 2,000 8,555E-05 4,927E-03 ! regulation of tissue remodeling GO:0034103 35 35 2,000 9,342E-05 5,217E-03 ! virus-host interaction GO:0019048 6 6 1,000 9,638E-05 5,225E-03 ! ER overload response GO:0006983 6 6 1,000 9,638E-05 5,075E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 9,638E-05 4,934E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 9,638E-05 4,801E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 9,638E-05 4,675E-03 ! localization within membrane GO:0051668 6 6 1,000 9,638E-05 4,555E-03 ! negative regulation of ossification GO:0030279 6 6 1,000 9,638E-05 4,441E-03 ! regulation of phagocytosis GO:0050764 6 6 1,000 9,638E-05 4,333E-03 ! positive regulation of cell migration GO:0030335 36 36 2,000 1,017E-04 4,465E-03 ! protein oligomerization GO:0051259 39 39 2,000 1,296E-04 5,554E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,347E-04 5,643E-03 ! response to X-ray GO:0010165 7 7 1,000 1,347E-04 5,518E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,347E-04 5,398E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,347E-04 5,283E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 8 7 1,000 1,347E-04 5,173E-03 ! regulation of ATPase activity GO:0043462 7 7 1,000 1,347E-04 5,067E-03 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,794E-04 6,611E-03 ! sex determination GO:0007530 8 8 1,000 1,794E-04 6,482E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,794E-04 6,357E-03 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 1,794E-04 6,237E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,794E-04 6,121E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,794E-04 6,01E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 2,302E-04 7,578E-03 ! regulation of cellular pH GO:0030641 9 9 1,000 2,302E-04 7,445E-03 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,302E-04 7,316E-03 ! regulation of calcium-mediated signaling GO:0050848 9 9 1,000 2,302E-04 7,192E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 2,57E-04 7,894E-03 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 2,73E-04 8,247E-03 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 2,874E-04 8,542E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 2,874E-04 8,406E-03 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 2,874E-04 8,275E-03 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,874E-04 8,148E-03 ! negative regulation of coagulation GO:0050819 11 10 1,000 2,874E-04 8,024E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 2,895E-04 7,965E-03 GO:0051325|interphase, ! response to light stimulus GO:0009416 53 52 2,000 3,068E-04 8,314E-03 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 3,432E-04 9,166E-03 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 3,507E-04 9,233E-03 ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 3,507E-04 9,103E-03 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! cellular response to starvation GO:0009267 11 11 1,000 3,507E-04 8,976E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 3,507E-04 8,853E-03 ! G1/S transition checkpoint GO:0031575 12 11 1,000 3,507E-04 8,734E-03 ! interaction with host GO:0051701 11 11 1,000 3,507E-04 8,617E-03 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 3,507E-04 8,504E-03 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 3,507E-04 8,393E-03 GO:0006109|regulation of carbohydrate metabolic process, ! reproductive developmental process GO:0003006 56 56 2,000 3,823E-04 9,032E-03 ! acute-phase response GO:0006953 12 12 1,000 4,202E-04 9,802E-03 ! G1 phase GO:0051318 13 12 1,000 4,202E-04 9,679E-03 ! negative regulation of translation GO:0017148 12 12 1,000 4,202E-04 9,56E-03 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 4,202E-04 9,443E-03 ! positive regulation of DNA replication GO:0045740 14 13 1,000 4,958E-04 0,01100876 ! gluconeogenesis GO:0006094 13 13 1,000 4,958E-04 0,0108777 ! mitochondrial membrane organization GO:0007006 13 13 1,000 4,958E-04 0,01074973 ! negative regulation of DNA replication GO:0008156 13 13 1,000 4,958E-04 0,01062473 ! actin filament bundle formation GO:0051017 13 13 1,000 4,958E-04 0,01050261 ! cell aging GO:0007569 13 13 1,000 4,958E-04 0,01038326 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 4,958E-04 0,01026659 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 4,958E-04 0,01015252 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 4,958E-04 0,01004095 GO:0001952|regulation of cell-matrix adhesion, ! regulation of response to external stimulus GO:0032101 65 64 2,000 5,671E-04 0,01136013 ! pyruvate metabolic process GO:0006090 14 14 1,000 5,775E-04 0,01144476 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 5,775E-04 0,01132301 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 5,775E-04 0,01120382 ! base-excision repair GO:0006284 14 14 1,000 5,775E-04 0,01108711 ! regulation of blood coagulation GO:0030193 15 14 1,000 5,775E-04 0,01097281 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 5,935E-04 0,01116235 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 6,208E-04 0,01155683 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 6,488E-04 0,01195797 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 6,653E-04 0,01214068 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 6,653E-04 0,01202165 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 6,653E-04 0,01190494 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 6,653E-04 0,01179046 ! response to starvation GO:0042594 15 15 1,000 6,653E-04 0,01167817 ! response to ionizing radiation GO:0010212 16 15 1,000 6,653E-04 0,011568 ! regulation of biomineral formation GO:0070167 15 15 1,000 6,653E-04 0,01145989 GO:0030500|regulation of bone mineralization, ! response to radiation GO:0009314 70 68 2,000 6,777E-04 0,01156426 ! positive regulation of transport GO:0051050 71 70 2,000 7,378E-04 0,01247444 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 7,592E-04 0,01272009 ! cellular response to nutrient levels GO:0031669 16 16 1,000 7,592E-04 0,0126055 ! positive regulation of catabolic process GO:0009896 16 16 1,000 7,592E-04 0,01249295 ! regulation of coagulation GO:0050818 17 16 1,000 7,592E-04 0,01238239 ! negative regulation of signal transduction GO:0009968 71 71 2,000 7,691E-04 0,01243314 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 8,591E-04 0,01376796 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 8,591E-04 0,01364927 ! regulation of transmembrane transport GO:0034762 17 17 1,000 8,591E-04 0,01353261 ! negative regulation of cell development GO:0010721 18 17 1,000 8,591E-04 0,01341792 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 8,591E-04 0,01330517 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 8,591E-04 0,01319429 ! negative regulation of cell communication GO:0010648 76 76 2,000 9,382E-04 0,01429043 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 9,65E-04 0,01457763 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 9,65E-04 0,01445911 ! hexose biosynthetic process GO:0019319 18 18 1,000 9,65E-04 0,01434251 ! B cell differentiation GO:0030183 18 18 1,000 9,65E-04 0,01422777 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 9,65E-04 0,01411485 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 9,65E-04 0,01400371 ! DNA damage checkpoint GO:0000077 19 19 1,000 1,077E-03 0,01550488 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 1,077E-03 0,01538468 ! regulation of pH GO:0006885 19 19 1,000 1,077E-03 0,01526634 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 1,077E-03 0,0151498 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 1,195E-03 0,01667972 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 1,195E-03 0,01655431 ! monosaccharide biosynthetic process GO:0046364 20 20 1,000 1,195E-03 0,01643077 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 1,318E-03 0,01799789 ! DNA integrity checkpoint GO:0031570 21 21 1,000 1,318E-03 0,01786555 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 1,318E-03 0,01773515 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 1,318E-03 0,01760663 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 1,344E-03 0,0178153 ! positive regulation of transferase activity GO:0051347 91 88 2,000 1,436E-03 0,01890432 GO:0033674|positive regulation of kinase activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 1,448E-03 0,01892588 ! epithelial cell differentiation GO:0030855 23 23 1,000 1,583E-03 0,0205505 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 1,583E-03 0,02040679 ! positive regulation of growth GO:0045927 23 23 1,000 1,583E-03 0,02026508 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 1,583E-03 0,02012532 ! calcium-mediated signaling GO:0019722 23 23 1,000 1,583E-03 0,01998748 ! mitochondrial transport GO:0006839 24 24 1,000 1,725E-03 0,02162267 ! gliogenesis GO:0042063 24 24 1,000 1,725E-03 0,02147657 ! T cell differentiation GO:0030217 24 24 1,000 1,725E-03 0,02133243 ! regulation of response to stress GO:0080134 97 94 2,000 1,737E-03 0,02134168 ! regulation of cell growth GO:0001558 97 96 2,000 1,845E-03 0,02252394 ! alcohol biosynthetic process GO:0046165 25 25 1,000 1,872E-03 0,02269459 ! heart morphogenesis GO:0003007 25 25 1,000 1,872E-03 0,02254626 ! negative regulation of cell migration GO:0030336 26 26 1,000 2,025E-03 0,02422895 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 2,025E-03 0,02407264 ! double-strand break repair GO:0006302 27 26 1,000 2,025E-03 0,02391833 ! response to insulin stimulus GO:0032868 28 26 1,000 2,025E-03 0,02376598 ! hemopoiesis GO:0030097 104 100 2,000 2,075E-03 0,02420236 ! activation of caspase activity GO:0006919 27 27 1,000 2,183E-03 0,02530518 ! positive regulation of cell cycle GO:0045787 29 29 1,000 2,517E-03 0,02899749 ! viral reproductive process GO:0022415 29 29 1,000 2,517E-03 0,02881738 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 2,517E-03 0,02863949 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 2,693E-03 0,03044973 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 2,693E-03 0,03026406 GO:0010863|positive regulation of phospholipase C activity, ! regulation of inflammatory response GO:0050727 30 30 1,000 2,693E-03 0,03008064 ! B cell activation GO:0042113 31 31 1,000 2,874E-03 0,03191202 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 2,874E-03 0,03172093 ! aging GO:0007568 32 31 1,000 2,874E-03 0,03153211 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 2,874E-03 0,03134553 ! negative regulation of cell growth GO:0030308 32 32 1,000 3,061E-03 0,03318714 ! regulation of phospholipase activity GO:0010517 32 32 1,000 3,061E-03 0,03299306 ! cell maturation GO:0048469 32 32 1,000 3,061E-03 0,03280124 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 3,061E-03 0,03261164 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 3,061E-03 0,03242422 ! positive regulation of lipase activity GO:0060193 32 32 1,000 3,061E-03 0,03223894 ! negative regulation of cell size GO:0045792 33 33 1,000 3,254E-03 0,03407109 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 3,254E-03 0,0338786 ! regulation of angiogenesis GO:0045765 35 34 1,000 3,452E-03 0,03573843 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 3,452E-03 0,03553877 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 3,452E-03 0,03534133 ! viral reproduction GO:0016032 34 34 1,000 3,452E-03 0,03514608 ! acute inflammatory response GO:0002526 35 35 1,000 3,655E-03 0,037014 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 3,655E-03 0,03681174 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 3,655E-03 0,03661167 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 3,864E-03 0,03849614 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of lipase activity GO:0060191 36 36 1,000 3,864E-03 0,03828917 ! coagulation GO:0050817 39 36 1,000 3,864E-03 0,03808441 GO:0007596|blood coagulation, ! response to drug GO:0042493 37 37 1,000 4,079E-03 0,03998459 ! lung development GO:0030324 38 37 1,000 4,079E-03 0,03977303 ! negative regulation of growth GO:0045926 37 37 1,000 4,079E-03 0,0395637 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 4,079E-03 0,03935656 ! urogenital system development GO:0001655 38 38 1,000 4,299E-03 0,04126277 ! regulation of homeostatic process GO:0032844 38 38 1,000 4,299E-03 0,04104898 ! hemostasis GO:0007599 42 39 1,000 4,524E-03 0,04297826 ! activation of MAPK activity GO:0000187 39 39 1,000 4,524E-03 0,04275786 ! respiratory tube development GO:0030323 40 39 1,000 4,524E-03 0,04253971 ! nucleotide-excision repair GO:0006289 40 39 1,000 4,524E-03 0,04232377 ! respiratory system development GO:0060541 40 39 1,000 4,524E-03 0,04211002 ! developmental maturation GO:0021700 39 39 1,000 4,524E-03 0,04189841 ! lymphocyte differentiation GO:0030098 39 39 1,000 4,524E-03 0,04168892 ! cell cycle checkpoint GO:0000075 42 41 1,000 4,991E-03 0,04576216 ! regulation of caspase activity GO:0043281 41 41 1,000 4,991E-03 0,04553562 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 5,232E-03 0,04750334 ! negative regulation of ligase activity GO:0051352 43 42 1,000 5,232E-03 0,04727048 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 5,232E-03 0,04703989 ! reproductive structure development GO:0048608 43 43 1,000 5,479E-03 0,04901916 ! mitochondrion organization GO:0007005 44 43 1,000 5,479E-03 0,04878235 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 5,731E-03 0,05078103 ! protein import into nucleus GO:0006606 44 44 1,000 5,731E-03 0,05053806 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 5,988E-03 0,05255549 ! nuclear import GO:0051170 45 45 1,000 5,988E-03 0,05230641 ! tube morphogenesis GO:0035239 47 46 1,000 6,251E-03 0,05434194 ! regulation of peptidase activity GO:0052547 46 46 1,000 6,251E-03 0,05408682 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 6,251E-03 0,05383408 ! positive regulation of ligase activity GO:0051351 47 46 1,000 6,251E-03 0,05358369 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 6,251E-03 0,05333561 ! regulation of catabolic process GO:0009894 48 47 1,000 6,519E-03 0,05536371 ! actin filament organization GO:0007015 50 48 1,000 6,792E-03 0,057417 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 6,792E-03 0,05715482 ! protein localization in nucleus GO:0034504 48 48 1,000 6,792E-03 0,05689503 ! leukocyte differentiation GO:0002521 50 49 1,000 7,07E-03 0,05895649 ! gland development GO:0048732 51 49 1,000 7,07E-03 0,05869092 ! cell cycle arrest GO:0007050 49 49 1,000 7,07E-03 0,05842773 ! regulation of ligase activity GO:0051340 50 49 1,000 7,07E-03 0,0581669 ! regulation of defense response GO:0031347 50 50 1,000 7,353E-03 0,06022807 ! T cell activation GO:0042110 51 50 1,000 7,353E-03 0,05996157 ! regulation of neurogenesis GO:0050767 51 50 1,000 7,353E-03 0,05969742 ! cell fate commitment GO:0045165 52 52 1,000 7,935E-03 0,06413746 ! regulation of body fluid levels GO:0050878 55 52 1,000 7,935E-03 0,06385738 ! response to hypoxia GO:0001666 53 53 1,000 8,233E-03 0,06597105 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 8,233E-03 0,06568546 ! response to oxygen levels GO:0070482 55 54 1,000 8,536E-03 0,06781295 ! hormone metabolic process GO:0042445 55 54 1,000 8,536E-03 0,06752191 ! in utero embryonic development GO:0001701 55 55 1,000 8,845E-03 0,06966276 ! regulation of cell adhesion GO:0030155 56 55 1,000 8,845E-03 0,06936632 ! regulation of nervous system development GO:0051960 57 56 1,000 9,158E-03 0,07152007 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,01012819 0,07876053 ! regulation of cell development GO:0060284 60 59 1,000 0,01012819 0,0784296 ! protein localization in organelle GO:0033365 59 59 1,000 0,01012819 0,07810144 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,01046127 0,08033381 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,0107992 0,08258474 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,0107992 0,08224348 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,01114196 0,08450464 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 1,000 0,01114196 0,08415831 ! glucose metabolic process GO:0006006 63 63 1,000 0,01148952 0,0864293 ! regulation of hormone levels GO:0010817 66 65 1,000 0,01219894 0,09139289 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,01256076 0,09372259 ! rRNA transcription GO:0009303 5 5 0,000 0,01301689 0,09673439 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,01301689 0,09634589 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,01301689 0,09596051 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,01301689 0,0955782 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,01301689 0,09519892 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,01301689 0,09482264 ! reproductive cellular process GO:0048610 5 5 0,000 0,01301689 0,09444932 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,01301689 0,09407893 ! metencephalon development GO:0022037 5 5 0,000 0,01301689 0,09371144 ! water transport GO:0006833 5 5 0,000 0,01301689 0,0933468 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,01301689 0,09298499 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,01301689 0,09262598 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,01301689 0,09226972 ! glycerol metabolic process GO:0006071 5 5 0,000 0,01301689 0,0919162 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,01301689 0,09156537 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,01301689 0,09121722 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,01301689 0,0908717 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,01301689 0,09052878 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,01301689 0,09018845 ! filopodium assembly GO:0046847 7 5 0,000 0,01301689 0,08985067 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,01301689 0,0895154 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,01301689 0,08918263 ! GTP metabolic process GO:0046039 5 5 0,000 0,01301689 0,08885233 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,01301689 0,08852446 ! mRNA stabilization GO:0048255 5 5 0,000 0,01301689 0,088199 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,01301689 0,08787593 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,01301689 0,08755521 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,01301689 0,08723683 ! social behavior GO:0035176 5 5 0,000 0,01301689 0,08692075 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,01301689 0,08660696 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,01301689 0,08629542 ! memory GO:0007613 5 5 0,000 0,01301689 0,08598612 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,01301689 0,08567903 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,01301689 0,08537412 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,01301689 0,08507138 ! response to lipid GO:0033993 5 5 0,000 0,01301689 0,08477077 ! erythrocyte maturation GO:0043249 5 5 0,000 0,01301689 0,08447228 ! hippocampus development GO:0021766 6 5 0,000 0,01301689 0,08417589 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,01301689 0,08388157 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,01301689 0,0835893 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,01301689 0,08329905 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,01301689 0,08301082 ! mechanosensory behavior GO:0007638 5 5 0,000 0,01301689 0,08272458 ! heart looping GO:0001947 5 5 0,000 0,01301689 0,0824403 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,01301689 0,08215797 ! response to interferon-gamma GO:0034341 5 5 0,000 0,01301689 0,08187757 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,01301689 0,08159907 ! endocrine pancreas development GO:0031018 5 5 0,000 0,01301689 0,08132247 ! pH reduction GO:0045851 5 5 0,000 0,01301689 0,08104773 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,01301689 0,08077484 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,01301689 0,08050378 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,01301689 0,08023454 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,01301689 0,07996709 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,01301689 0,07970142 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,01301689 0,07943751 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,01301689 0,07917534 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,01301689 0,07891489 ! adrenal gland development GO:0030325 5 5 0,000 0,01301689 0,07865616 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,01301689 0,07839911 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,01301689 0,07814374 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,01301689 0,07789003 ! astrocyte differentiation GO:0048708 5 5 0,000 0,01301689 0,07763795 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,01301689 0,07738751 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,01301689 0,07713867 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,01301689 0,07689144 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,01301689 0,07664578 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,01301689 0,07640168 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,01301689 0,07615914 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,01301689 0,07591813 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,01301689 0,07567864 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,01301689 0,07544065 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,01301689 0,07520416 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,01301689 0,07496915 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,01301689 0,0747356 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,01301689 0,0745035 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,01301689 0,07427284 ! response to ATP GO:0033198 5 5 0,000 0,01301689 0,0740436 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,01301689 0,07381578 ! regulation of appetite GO:0032098 5 5 0,000 0,01301689 0,07358935 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,01301689 0,07336431 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,01301689 0,07314063 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,01301689 0,07291832 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,01301689 0,07269736 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01301689 0,07247773 ! receptor clustering GO:0043113 5 5 0,000 0,01301689 0,07225942 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,01301689 0,07204243 ! fear response GO:0042596 5 5 0,000 0,01301689 0,07182673 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,01301689 0,07161232 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,01301689 0,07139919 ! retinol metabolic process GO:0042572 5 5 0,000 0,01301689 0,07118732 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,01301689 0,07097671 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,01301689 0,07076734 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,01301689 0,0705592 ! parturition GO:0007567 5 5 0,000 0,01301689 0,07035228 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01301689 0,07014657 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,01301689 0,06994206 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,01301689 0,06973874 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,01301689 0,0695366 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,01301689 0,06933563 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,01301689 0,06913582 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,01301689 0,06893715 ! response to UV-B GO:0010224 5 5 0,000 0,01301689 0,06873962 ! oligodendrocyte development GO:0014003 5 5 0,000 0,01301689 0,06854322 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,01301689 0,06834794 ! activated T cell proliferation GO:0050798 5 5 0,000 0,01301689 0,06815377 ! interaction with symbiont GO:0051702 5 5 0,000 0,01301689 0,0679607 ! cellular extravasation GO:0045123 5 5 0,000 0,01301689 0,06776872 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,01301689 0,06757782 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,01301689 0,067388 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,01301689 0,06719924 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,01301689 0,06701153 ! response to amine stimulus GO:0014075 5 5 0,000 0,01301689 0,06682487 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,01301689 0,06663924 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,01301689 0,06645465 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,01301689 0,06627107 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,01301689 0,06608851 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,01301689 0,06590694 ! neuron recognition GO:0008038 5 5 0,000 0,01301689 0,06572638 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,01301689 0,0655468 ! decidualization GO:0046697 5 5 0,000 0,01301689 0,0653682 ! hair follicle maturation GO:0048820 5 5 0,000 0,01301689 0,06519056 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,01301689 0,0650139 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,01301689 0,06483818 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,01301689 0,06466342 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,01301689 0,06448959 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,01301689 0,0643167 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,01301689 0,06414473 ! postreplication repair GO:0006301 5 5 0,000 0,01301689 0,06397367 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,01301689 0,06380353 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,01301689 0,06363429 ! histone methylation GO:0016571 5 5 0,000 0,01301689 0,06346595 ! DNA methylation GO:0006306 5 5 0,000 0,01301689 0,06329849 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01301689 0,06313192 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,01301689 0,06296621 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,01301689 0,06280138 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,01301689 0,06263741 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,01301689 0,06247429 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,01301689 0,06231202 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,01301689 0,06215059 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,01301689 0,06198999 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,01301689 0,06183023 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,01301689 0,06167128 ! sterol catabolic process GO:0016127 5 5 0,000 0,01301689 0,06151315 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,01301689 0,06135583 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,01301689 0,06119931 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,01301689 0,06104358 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,01301689 0,06088865 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,01301689 0,0607345 ! zymogen activation GO:0031638 5 5 0,000 0,01301689 0,06058113 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,01301689 0,06042853 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,01301689 0,0602767 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,01301689 0,06012563 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,01301689 0,05997532 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,01301689 0,05982576 ! nucleosome positioning GO:0016584 5 5 0,000 0,01301689 0,05967693 ! regulation of isotype switching GO:0045191 5 5 0,000 0,01301689 0,05952885 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,01301689 0,0593815 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,01301689 0,05923488 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,01301689 0,05908898 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,01301689 0,0589438 ! NADPH regeneration GO:0006740 5 5 0,000 0,01301689 0,05879933 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,01301689 0,05865557 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,01301689 0,05851251 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,01301689 0,05837014 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,01301689 0,05822847 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,01301689 0,05808748 ! sarcomere organization GO:0045214 5 5 0,000 0,01301689 0,05794717 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,01301689 0,05780754 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,01301689 0,05766858 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,01301689 0,05753028 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,01301689 0,05739265 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,01301689 0,05725568 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,01301689 0,05711935 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,01301689 0,05698368 ! spleen development GO:0048536 5 5 0,000 0,01301689 0,05684864 ! male genitalia development GO:0030539 5 5 0,000 0,01301689 0,05671425 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,01301689 0,05658049 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,01301689 0,05644736 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,01301689 0,05631485 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,01301689 0,05618297 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,01301689 0,0560517 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,01301689 0,05592104 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,01301689 0,05579099 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,01301689 0,05566155 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,01301689 0,0555327 ! ATP catabolic process GO:0006200 5 5 0,000 0,01301689 0,05540445 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01301689 0,05527679 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,01301689 0,05514972 ! blastocyst formation GO:0001825 5 5 0,000 0,01301689 0,05502323 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,01301689 0,05489732 ! embryonic gut development GO:0048566 5 5 0,000 0,01301689 0,05477198 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,01301689 0,05464722 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,01301689 0,05452302 ! activation of innate immune response GO:0002218 5 5 0,000 0,01301689 0,05439938 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,01301689 0,05427631 ! catecholamine transport GO:0051937 5 5 0,000 0,01301689 0,05415379 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,01301689 0,05403182 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,01301689 0,0539104 ! muscle adaptation GO:0043500 5 5 0,000 0,01301689 0,05378952 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,01301689 0,05366919 ! embryonic heart tube development GO:0035050 5 5 0,000 0,01301689 0,05354939 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,01301689 0,05343013 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,01301689 0,0533114 ! defense response to fungus GO:0050832 5 5 0,000 0,01301689 0,05319319 ! lysogeny GO:0030069 5 5 0,000 0,01301689 0,0530755 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,01301689 0,05295834 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,01301689 0,05284169 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,01301689 0,05272556 ! response to nicotine GO:0035094 5 5 0,000 0,01301689 0,05260993 ! establishment of cell polarity GO:0030010 5 5 0,000 0,01301689 0,05249481 ! mitochondrion localization GO:0051646 5 5 0,000 0,01301689 0,05238019 ! nucleus localization GO:0051647 5 5 0,000 0,01301689 0,05226607 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,01301689 0,05215245 ! regulation of cell size GO:0008361 68 68 1,000 0,01329848 0,05316508 ! regulation of translation GO:0006417 69 69 1,000 0,01367434 0,05454936 ! response to nutrient levels GO:0031667 69 69 1,000 0,01367434 0,05443154 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,01367434 0,05431423 ! wound healing GO:0042060 74 70 1,000 0,01405482 0,05570546 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,01443992 0,05710895 GO:0006874|cellular calcium ion homeostasis, ! response to extracellular stimulus GO:0009991 72 72 1,000 0,0148296 0,05852451 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,01560099 0,06143724 ! axon extension GO:0048675 7 6 0,000 0,01560099 0,06130624 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,01560099 0,0611758 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,01560099 0,06104592 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,01560099 0,06091658 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,01560099 0,06078779 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,01560099 0,06065955 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,01560099 0,06053185 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,01560099 0,06040468 ! regulation of S phase GO:0033261 6 6 0,000 0,01560099 0,06027804 ! myotube differentiation GO:0014902 6 6 0,000 0,01560099 0,06015194 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,01560099 0,06002636 ! bone remodeling GO:0046849 6 6 0,000 0,01560099 0,05990131 ! N-glycan processing GO:0006491 6 6 0,000 0,01560099 0,05977677 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,01560099 0,05965275 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,01560099 0,05952925 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,01560099 0,05940625 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,01560099 0,05928377 ! RNA methylation GO:0001510 6 6 0,000 0,01560099 0,05916178 ! cartilage condensation GO:0001502 7 6 0,000 0,01560099 0,0590403 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,01560099 0,05891932 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,01560099 0,05879883 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,01560099 0,05867883 ! artery development GO:0060840 6 6 0,000 0,01560099 0,05855932 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,01560099 0,0584403 ! bile acid metabolic process GO:0008206 6 6 0,000 0,01560099 0,05832176 ! androgen metabolic process GO:0008209 6 6 0,000 0,01560099 0,0582037 ! estrogen metabolic process GO:0008210 6 6 0,000 0,01560099 0,05808611 ! limbic system development GO:0021761 7 6 0,000 0,01560099 0,057969 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,01560099 0,05785237 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,01560099 0,0577362 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,01560099 0,05762049 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,01560099 0,05750525 ! pathogenesis GO:0009405 6 6 0,000 0,01560099 0,05739047 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,01560099 0,05727615 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,01560099 0,05716228 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,01560099 0,05704886 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,01560099 0,05693589 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,01560099 0,05682337 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,01560099 0,05671129 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,01560099 0,05659966 ! arginine metabolic process GO:0006525 6 6 0,000 0,01560099 0,05648846 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,01560099 0,0563777 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,01560099 0,05626737 ! glutamate catabolic process GO:0006538 7 6 0,000 0,01560099 0,05615747 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,01560099 0,056048 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,01560099 0,05593896 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,01560099 0,05583034 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,01560099 0,05572214 ! V(D)J recombination GO:0033151 6 6 0,000 0,01560099 0,05561436 ! focal adhesion formation GO:0048041 7 6 0,000 0,01560099 0,055507 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,01560099 0,05540005 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,01560099 0,05529351 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,01560099 0,05518738 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,01560099 0,05508166 ! regulation of heart rate GO:0002027 6 6 0,000 0,01560099 0,05497634 ! lipid digestion GO:0044241 6 6 0,000 0,01560099 0,05487142 ! asymmetric protein localization GO:0008105 6 6 0,000 0,01560099 0,05476691 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,01560099 0,05466279 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,01560099 0,05455906 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,01560099 0,05445573 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,01560099 0,05435279 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,01560099 0,05425024 ! ruffle organization GO:0031529 6 6 0,000 0,01560099 0,05414807 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,01560099 0,05404629 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,01560099 0,05394489 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,01560099 0,05384387 ! neutral amino acid transport GO:0015804 6 6 0,000 0,01560099 0,05374323 ! L-amino acid transport GO:0015807 6 6 0,000 0,01560099 0,05364296 ! bone mineralization GO:0030282 6 6 0,000 0,01560099 0,05354307 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,01560099 0,05344354 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,01560099 0,05334439 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,01560099 0,0532456 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,01560099 0,05314718 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,01560099 0,05304913 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,01560099 0,05295143 ! regulation of organ growth GO:0046620 6 6 0,000 0,01560099 0,05285409 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,01560099 0,05275711 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,01560099 0,05266049 ! response to dsRNA GO:0043331 6 6 0,000 0,01560099 0,05256422 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,01560099 0,0524683 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,01560099 0,05237273 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,01560099 0,0522775 ! genitalia development GO:0048806 6 6 0,000 0,01560099 0,05218263 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,01560099 0,05208809 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,01560099 0,0519939 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,01560099 0,05190005 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,01560099 0,05180653 ! multicellular organismal aging GO:0010259 6 6 0,000 0,01560099 0,05171336 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,01560099 0,05162051 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,01560099 0,051528 ! erythrocyte development GO:0048821 6 6 0,000 0,01560099 0,05143583 ! renal water homeostasis GO:0003091 6 6 0,000 0,01560099 0,05134398 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,01560099 0,05125245 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,01560099 0,05116126 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,01560099 0,05107038 ! ribosome assembly GO:0042255 6 6 0,000 0,01560099 0,05097983 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,01560099 0,0508896 ! diencephalon development GO:0021536 6 6 0,000 0,01560099 0,05079969 ! fucose catabolic process GO:0019317 6 6 0,000 0,01560099 0,0507101 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,01560099 0,05062082 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,01560099 0,05053186 ! regulation of lipid transport GO:0032368 6 6 0,000 0,01560099 0,0504432 ! regulation of cell division GO:0051302 6 6 0,000 0,01560099 0,05035486 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,01560099 0,05026683 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,01560099 0,0501791 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,01560099 0,05009168 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,01560099 0,05000457 ! neuroblast proliferation GO:0007405 6 6 0,000 0,01560099 0,04991775 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,01560099 0,04983124 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,01560099 0,04974503 ! regulation of glucose transport GO:0010827 6 6 0,000 0,01560099 0,04965911 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,01560099 0,04957349 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,01560099 0,04948817 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,01560099 0,04940314 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,01560099 0,0493184 ! thymus development GO:0048538 6 6 0,000 0,01560099 0,04923395 ! lymph node development GO:0048535 6 6 0,000 0,01560099 0,04914979 ! organic cation transport GO:0015695 6 6 0,000 0,01560099 0,04906592 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,01560099 0,04898233 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,01560099 0,04889902 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,01560099 0,048816 ! sperm-egg recognition GO:0035036 7 6 0,000 0,01560099 0,04873327 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,01560099 0,04865081 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,01560099 0,04856863 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,01560099 0,04848672 ! alditol metabolic process GO:0019400 6 6 0,000 0,01560099 0,04840509 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,01560099 0,04832374 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,01560099 0,04824266 ! maternal placenta development GO:0001893 6 6 0,000 0,01560099 0,04816185 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,01560099 0,04808132 ! response to oxidative stress GO:0006979 76 75 1,000 0,01602589 0,04930839 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,01684591 0,05174502 ! regulation of protein modification process GO:0031399 79 78 1,000 0,01726259 0,0529367 ! metal ion homeostasis GO:0055065 78 78 1,000 0,01726259 0,05284876 ! nuclear transport GO:0051169 79 79 1,000 0,01768369 0,05404817 GO:0006913|nucleocytoplasmic transport, ! respiratory burst GO:0045730 7 7 0,000 0,0181787 0,05546912 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,0181787 0,05537743 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,0181787 0,05528605 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,0181787 0,05519497 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,0181787 0,05510419 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,0181787 0,05501371 ! regulation of chemokine production GO:0032642 7 7 0,000 0,0181787 0,05492352 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,0181787 0,05483363 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,0181787 0,05474403 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,0181787 0,05465473 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,0181787 0,05456571 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,0181787 0,05447699 ! gene silencing by RNA GO:0031047 7 7 0,000 0,0181787 0,05438855 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,0181787 0,0543004 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,0181787 0,05421254 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,0181787 0,05412495 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,0181787 0,05403766 ! axis specification GO:0009798 7 7 0,000 0,0181787 0,05395064 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,0181787 0,0538639 ! visual behavior GO:0007632 7 7 0,000 0,0181787 0,05377744 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,0181787 0,05369126 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,0181787 0,05360536 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,0181787 0,05351972 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,0181787 0,05343437 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,0181787 0,05334928 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,0181787 0,05326446 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,0181787 0,05317992 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,0181787 0,05309564 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,0181787 0,05301162 ! digestive system development GO:0055123 7 7 0,000 0,0181787 0,05292788 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,0181787 0,0528444 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,0181787 0,05276118 ! protein targeting to ER GO:0045047 8 7 0,000 0,0181787 0,05267822 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,0181787 0,05259552 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,0181787 0,05251308 ! endoderm development GO:0007492 7 7 0,000 0,0181787 0,0524309 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,0181787 0,05234898 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,0181787 0,05226731 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,0181787 0,0521859 ! response to hexose stimulus GO:0009746 7 7 0,000 0,0181787 0,05210474 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,0181787 0,05202383 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,0181787 0,05194317 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,0181787 0,05186277 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,0181787 0,05178261 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,0181787 0,0517027 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,0181787 0,05162303 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,0181787 0,05154361 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,0181787 0,05146443 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,0181787 0,0513855 ! UV protection GO:0009650 7 7 0,000 0,0181787 0,05130681 ! DNA integration GO:0015074 7 7 0,000 0,0181787 0,05122836 ! myofibril assembly GO:0030239 7 7 0,000 0,0181787 0,05115015 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,0181787 0,05107218 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,0181787 0,05099444 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,0181787 0,05091694 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,0181787 0,05083968 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,0181787 0,05076265 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,0181787 0,05068585 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,0181787 0,05060929 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,0181787 0,05053295 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,0181787 0,05045685 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,0181787 0,05038097 ! axon cargo transport GO:0008088 7 7 0,000 0,0181787 0,05030533 ! eating behavior GO:0042755 7 7 0,000 0,0181787 0,05022991 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,0181787 0,05015471 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,0181787 0,05007974 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,0181787 0,050005 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,0181787 0,04993047 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,0181787 0,04985617 ! cranial nerve development GO:0021545 7 7 0,000 0,0181787 0,04978209 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,0181787 0,04970823 ! induction of an organ GO:0001759 7 7 0,000 0,0181787 0,04963459 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,0181787 0,04956116 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,0181787 0,04948796 ! autonomic nervous system development GO:0048483 7 7 0,000 0,0181787 0,04941497 ! intracellular lipid transport GO:0032365 7 7 0,000 0,0181787 0,04934219 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,0181787 0,04926963 ! platelet activation GO:0030168 8 7 0,000 0,0181787 0,04919728 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,0181787 0,04912514 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,0181787 0,04905322 ! natural killer cell activation GO:0030101 7 7 0,000 0,0181787 0,0489815 ! NADP metabolic process GO:0006739 7 7 0,000 0,0181787 0,04891 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,0181787 0,0488387 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,0181787 0,04876761 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,0181787 0,04869673 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,0181787 0,04862605 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,0181787 0,04855558 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,0181787 0,04848531 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,0181787 0,04841524 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,0181787 0,04834538 ! cell-cell recognition GO:0009988 8 7 0,000 0,0181787 0,04827572 ! hormone catabolic process GO:0042447 7 7 0,000 0,0181787 0,04820625 ! dopamine metabolic process GO:0042417 7 7 0,000 0,0181787 0,04813699 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,0181787 0,04806793 ! oxygen transport GO:0015671 7 7 0,000 0,0181787 0,04799906 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,0181787 0,0479304 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,0181787 0,04786192 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,0181787 0,04779365 ! regulation of axon extension GO:0030516 7 7 0,000 0,0181787 0,04772557 ! cell killing GO:0001906 7 7 0,000 0,0181787 0,04765768 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,0181787 0,04758998 ! adult feeding behavior GO:0008343 7 7 0,000 0,0181787 0,04752248 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,0181787 0,04745517 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,0181787 0,04738804 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,0181787 0,04732111 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,0181787 0,04725437 ! response to cold GO:0009409 7 7 0,000 0,0181787 0,04718781 ! MAPKKK cascade GO:0000165 82 81 1,000 0,01853906 0,04805553 ! tube development GO:0035295 83 81 1,000 0,01853906 0,04798804 ! lymphocyte activation GO:0046649 82 81 1,000 0,01853906 0,04792073 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02075004 0,05356067 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02075004 0,05348576 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02075004 0,05341106 ! positive regulation of translation GO:0045727 8 8 0,000 0,02075004 0,05333656 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02075004 0,05326228 ! superoxide anion generation GO:0042554 8 8 0,000 0,02075004 0,0531882 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02075004 0,05311433 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02075004 0,05304066 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02075004 0,0529672 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02075004 0,05289394 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02075004 0,05282088 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02075004 0,05274802 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02075004 0,05267537 ! zinc ion transport GO:0006829 8 8 0,000 0,02075004 0,05260291 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02075004 0,05253065 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02075004 0,0524586 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02075004 0,05238674 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02075004 0,05231507 ! lipid localization GO:0010876 8 8 0,000 0,02075004 0,0522436 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02075004 0,05217233 ! response to cAMP GO:0051591 8 8 0,000 0,02075004 0,05210125 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02075004 0,05203036 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02075004 0,05195967 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02075004 0,05188917 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02075004 0,05181886 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02075004 0,05174874 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02075004 0,05167881 ! sensory perception of taste GO:0050909 8 8 0,000 0,02075004 0,05160906 ! organelle fusion GO:0048284 8 8 0,000 0,02075004 0,05153951 ! pancreas development GO:0031016 8 8 0,000 0,02075004 0,05147014 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02075004 0,05140096 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02075004 0,05133197 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02075004 0,05126316 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02075004 0,05119453 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02075004 0,05112609 ! sperm motility GO:0030317 8 8 0,000 0,02075004 0,05105783 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02075004 0,05098976 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02075004 0,05092186 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02075004 0,05085414 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02075004 0,05078661 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02075004 0,05071925 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02075004 0,05065208 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02075004 0,05058508 ! Golgi organization GO:0007030 8 8 0,000 0,02075004 0,05051825 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02075004 0,05045161 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02075004 0,05038513 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,02075004 0,05031884 ! fructose metabolic process GO:0006000 8 8 0,000 0,02075004 0,05025272 ! mannose metabolic process GO:0006013 9 8 0,000 0,02075004 0,05018677 ! NAD metabolic process GO:0019674 8 8 0,000 0,02075004 0,05012099 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02075004 0,05005539 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02075004 0,04998996 ! response to fungus GO:0009620 8 8 0,000 0,02075004 0,0499247 ! stem cell differentiation GO:0048863 8 8 0,000 0,02075004 0,0498596 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02075004 0,04979468 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02075004 0,04972993 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02075004 0,04966535 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02075004 0,04960093 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02075004 0,04953668 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02075004 0,0494726 ! vasoconstriction GO:0042310 8 8 0,000 0,02075004 0,04940868 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02075004 0,04934492 ! muscle cell development GO:0055001 8 8 0,000 0,02075004 0,04928134 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02075004 0,04921791 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02075004 0,04915465 ! sensory perception of pain GO:0019233 8 8 0,000 0,02075004 0,04909155 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02075004 0,04902861 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02075004 0,04896583 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02075004 0,04890322 ! chromatin silencing GO:0006342 8 8 0,000 0,02075004 0,04884076 ! tissue regeneration GO:0042246 8 8 0,000 0,02075004 0,04877847 ! salivary gland development GO:0007431 8 8 0,000 0,02075004 0,04871633 ! T cell homeostasis GO:0043029 8 8 0,000 0,02075004 0,04865435 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02075004 0,04859252 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,02075004 0,04853086 ! water homeostasis GO:0030104 8 8 0,000 0,02075004 0,04846935 ! cofactor transport GO:0051181 8 8 0,000 0,02075004 0,048408 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02075004 0,0483468 ! acid secretion GO:0046717 8 8 0,000 0,02075004 0,04828575 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02075004 0,04822486 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02075004 0,04816413 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02075004 0,04810354 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02075004 0,04804311 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02075004 0,04798283 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02075004 0,0479227 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02075004 0,04786272 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02075004 0,0478029 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02075004 0,04774322 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02075004 0,04768369 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02075004 0,0476243 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02075004 0,04756507 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02075004 0,04750598 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02075004 0,04744704 ! developmental induction GO:0031128 8 8 0,000 0,02075004 0,04738825 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02075004 0,0473296 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02075004 0,0472711 ! actin filament polymerization GO:0030041 9 8 0,000 0,02075004 0,04721274 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,02075004 0,04715452 ! peptide hormone processing GO:0016486 8 8 0,000 0,02075004 0,04709645 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02075004 0,04703852 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02075004 0,04698073 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,02075318 0,04693019 ! hexose metabolic process GO:0019318 87 86 1,000 0,02075318 0,04687268 ! heart development GO:0007507 90 87 1,000 0,0212088 0,0478431 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,02213265 0,0498661 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,02307317 0,05192168 ! lactation GO:0007595 10 9 0,000 0,02331501 0,05240191 ! embryonic pattern specification GO:0009880 10 9 0,000 0,02331501 0,05233808 ! positive regulation of cell size GO:0045793 9 9 0,000 0,02331501 0,05227441 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,02331501 0,05221089 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,02331501 0,05214753 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,02331501 0,05208432 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,02331501 0,05202126 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,02331501 0,05195836 ! viral genome replication GO:0019079 9 9 0,000 0,02331501 0,05189561 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,02331501 0,05183301 ! copper ion transport GO:0006825 9 9 0,000 0,02331501 0,05177056 ! lipid phosphorylation GO:0046834 9 9 0,000 0,02331501 0,05170826 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,02331501 0,05164611 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,02331501 0,05158411 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,02331501 0,05152226 ! RNA polyadenylation GO:0043631 9 9 0,000 0,02331501 0,05146055 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,02331501 0,051399 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,02331501 0,05133759 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,02331501 0,05127633 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,02331501 0,05121521 ! phospholipid efflux GO:0033700 9 9 0,000 0,02331501 0,05115424 ! response to alkaloid GO:0043279 10 9 0,000 0,02331501 0,05109342 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,02331501 0,05103274 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,02331501 0,0509722 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,02331501 0,0509118 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,02331501 0,05085155 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,02331501 0,05079145 ! response to ethanol GO:0045471 9 9 0,000 0,02331501 0,05073148 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,02331501 0,05067165 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,02331501 0,05061197 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,02331501 0,05055243 ! methionine metabolic process GO:0006555 9 9 0,000 0,02331501 0,05049302 ! glutamine metabolic process GO:0006541 9 9 0,000 0,02331501 0,05043376 ! cerebral cortex development GO:0021987 9 9 0,000 0,02331501 0,05037463 ! response to osmotic stress GO:0006970 9 9 0,000 0,02331501 0,05031565 ! pigmentation during development GO:0048066 9 9 0,000 0,02331501 0,0502568 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,02331501 0,05019809 ! central nervous system neuron development GO:0021954 10 9 0,000 0,02331501 0,05013951 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,02331501 0,05008108 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,02331501 0,05002277 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,02331501 0,04996461 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,02331501 0,04990658 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,02331501 0,04984868 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,02331501 0,04979092 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,02331501 0,04973329 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,02331501 0,0496758 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,02331501 0,04961843 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,02331501 0,0495612 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,02331501 0,04950411 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,02331501 0,04944714 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,02331501 0,0493903 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,02331501 0,0493336 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,02331501 0,04927702 ! DNA replication initiation GO:0006270 9 9 0,000 0,02331501 0,04922058 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,02331501 0,04916426 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,02331501 0,04910807 ! histone acetylation GO:0016573 9 9 0,000 0,02331501 0,04905201 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,02331501 0,04899608 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,02331501 0,04894028 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,02331501 0,0488846 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,02331501 0,04882905 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,02331501 0,04877362 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,02331501 0,04871833 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,02331501 0,04866315 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,02331501 0,0486081 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,02331501 0,04855318 ! collagen catabolic process GO:0030574 9 9 0,000 0,02331501 0,04849838 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,02331501 0,0484437 ! purine base metabolic process GO:0006144 9 9 0,000 0,02331501 0,04838915 ! gas transport GO:0015669 9 9 0,000 0,02331501 0,04833472 ! cholesterol efflux GO:0033344 9 9 0,000 0,02331501 0,04828041 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,02331501 0,04822622 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,02331501 0,04817216 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,02331501 0,04811821 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,02331501 0,04806439 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,02331501 0,04801069 ! defense response to virus GO:0051607 9 9 0,000 0,02331501 0,0479571 ! actin filament-based movement GO:0030048 9 9 0,000 0,02331501 0,04790364 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,02331501 0,04785029 ! tissue morphogenesis GO:0048729 94 93 1,000 0,02403018 0,04926321 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,02587364 0,05298346 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,02587364 0,05292465 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,02587364 0,05286598 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,02587364 0,05280744 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,02587364 0,05274902 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,02587364 0,05269073 ! neuron maturation GO:0042551 10 10 0,000 0,02587364 0,05263258 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,02587364 0,05257455 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,02587364 0,05251665 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,02587364 0,05245887 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,02587364 0,05240122 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,02587364 0,0523437 ! hormone secretion GO:0046879 10 10 0,000 0,02587364 0,05228631 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,02587364 0,05222904 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,02587364 0,0521719 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,02587364 0,05211488 ! inositol metabolic process GO:0006020 10 10 0,000 0,02587364 0,05205798 ! cAMP metabolic process GO:0046058 10 10 0,000 0,02587364 0,05200121 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,02587364 0,05194457 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,02587364 0,05188805 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,02587364 0,05183165 ! glial cell development GO:0021782 10 10 0,000 0,02587364 0,05177537 ! phototransduction GO:0007602 11 10 0,000 0,02587364 0,05171921 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,02587364 0,05166318 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,02587364 0,05160727 ! fat cell differentiation GO:0045444 10 10 0,000 0,02587364 0,05155147 ! myoblast differentiation GO:0045445 10 10 0,000 0,02587364 0,0514958 ! centrosome cycle GO:0007098 10 10 0,000 0,02587364 0,05144025 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,02587364 0,05138482 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,02587364 0,05132951 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,02587364 0,05127432 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,02587364 0,05121924 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,02587364 0,05116429 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,02587364 0,05110945 ! protein polyubiquitination GO:0000209 10 10 0,000 0,02587364 0,05105473 ! glutamate metabolic process GO:0006536 11 10 0,000 0,02587364 0,05100012 ! plasma membrane organization GO:0007009 10 10 0,000 0,02587364 0,05094563 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,02587364 0,05089126 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,02587364 0,05083701 ! lysosomal transport GO:0007041 10 10 0,000 0,02587364 0,05078287 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,02587364 0,05072884 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,02587364 0,05067494 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,02587364 0,05062114 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,02587364 0,05056746 ! exocrine system development GO:0035272 10 10 0,000 0,02587364 0,05051389 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,02587364 0,05046044 ! neuromuscular junction development GO:0007528 10 10 0,000 0,02587364 0,0504071 ! embryo implantation GO:0007566 11 10 0,000 0,02587364 0,05035387 ! regulation of protein binding GO:0043393 11 10 0,000 0,02587364 0,05030075 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,02587364 0,05024775 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,02587364 0,05019486 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,02587364 0,05014208 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,02587364 0,05008941 ! protein export from nucleus GO:0006611 10 10 0,000 0,02587364 0,05003685 ! negative regulation of immune response GO:0050777 10 10 0,000 0,02587364 0,0499844 ! cytolysis GO:0019835 10 10 0,000 0,02587364 0,04993206 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,02587364 0,04987983 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,02587364 0,04982771 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,02587364 0,04977569 ! histone deacetylation GO:0016575 10 10 0,000 0,02587364 0,04972379 ! mRNA splice site selection GO:0006376 11 10 0,000 0,02587364 0,04967199 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,02587364 0,04962031 ! gland morphogenesis GO:0022612 10 10 0,000 0,02587364 0,04956873 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,02587364 0,04951725 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,02587364 0,04946589 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,02587364 0,04941463 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,02587364 0,04936347 ! regulation of epidermis development GO:0045682 10 10 0,000 0,02587364 0,04931242 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,02587364 0,04926148 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,02587364 0,04921064 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,02587364 0,04915991 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,02587364 0,04910928 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,02587364 0,04905876 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,02587364 0,04900834 ! nerve development GO:0021675 10 10 0,000 0,02587364 0,04895802 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,02587364 0,04890781 ! gut development GO:0048565 10 10 0,000 0,02587364 0,0488577 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,02587364 0,04880769 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,02587364 0,04875779 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,02587364 0,04870798 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,02587364 0,04865828 ! protein stabilization GO:0050821 10 10 0,000 0,02587364 0,04860868 ! endocytosis GO:0006897 99 98 1,000 0,0264937 0,0497229 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,0264937 0,04967232 ! response to hormone stimulus GO:0009725 102 100 1,000 0,02750704 0,05151979 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,02750704 0,05146749 ! protein secretion GO:0009306 11 11 0,000 0,02842593 0,05313286 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,02842593 0,05307902 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,02842593 0,0530253 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,02842593 0,05297168 ! negative regulation of defense response GO:0031348 11 11 0,000 0,02842593 0,05291818 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,02842593 0,05286478 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,02842593 0,05281149 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,02842593 0,0527583 ! skin development GO:0043588 11 11 0,000 0,02842593 0,05270523 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,02842593 0,05265226 ! signal complex assembly GO:0007172 11 11 0,000 0,02842593 0,05259939 ! microtubule-based transport GO:0010970 11 11 0,000 0,02842593 0,05254664 ! endothelial cell migration GO:0043542 11 11 0,000 0,02842593 0,05249398 ! peroxisomal transport GO:0043574 11 11 0,000 0,02842593 0,05244144 ! protein amino acid methylation GO:0006479 11 11 0,000 0,02842593 0,052389 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,02842593 0,05233666 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,02842593 0,05228443 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,02842593 0,0522323 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,02842593 0,05218027 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,02842593 0,05212835 ! T cell proliferation GO:0042098 11 11 0,000 0,02842593 0,05207654 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,02842593 0,05202482 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,02842593 0,05197321 ! spinal cord development GO:0021510 11 11 0,000 0,02842593 0,0519217 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,02842593 0,05187029 ! smooth muscle contraction GO:0006939 11 11 0,000 0,02842593 0,05181899 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,02842593 0,05176778 ! digestive system process GO:0022600 11 11 0,000 0,02842593 0,05171668 ! mitotic spindle organization GO:0007052 11 11 0,000 0,02842593 0,05166568 ! fucose metabolic process GO:0006004 11 11 0,000 0,02842593 0,05161477 ! membrane budding GO:0006900 11 11 0,000 0,02842593 0,05156397 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,02842593 0,05151327 ! monoamine transport GO:0015844 11 11 0,000 0,02842593 0,05146267 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,02842593 0,05141216 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,02842593 0,05136176 ! body fluid secretion GO:0007589 11 11 0,000 0,02842593 0,05131146 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,02842593 0,05126125 ! intermediate filament-based process GO:0045103 11 11 0,000 0,02842593 0,05121114 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,02842593 0,05116113 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,02842593 0,05111122 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,02842593 0,0510614 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,02842593 0,05101168 ! oogenesis GO:0048477 11 11 0,000 0,02842593 0,05096206 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,02842593 0,05091253 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,02842593 0,0508631 ! vitamin transport GO:0051180 11 11 0,000 0,02842593 0,05081377 ! muscle maintenance GO:0046716 12 11 0,000 0,02842593 0,05076453 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,02842593 0,05071539 ! hindbrain development GO:0030902 11 11 0,000 0,02842593 0,05066634 ! steroid catabolic process GO:0006706 11 11 0,000 0,02842593 0,05061739 ! endocrine process GO:0050886 11 11 0,000 0,02842593 0,05056853 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,02842593 0,05051976 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,02842593 0,05047109 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,02842593 0,05042252 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,02842593 0,05037403 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,02842593 0,05032564 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,03097191 0,05478046 ! translational initiation GO:0006413 12 12 0,000 0,03097191 0,05472793 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,03097191 0,05467551 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,03097191 0,05462319 ! initiation of viral infection GO:0019059 12 12 0,000 0,03097191 0,05457097 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,03097191 0,05451885 ! iron ion transport GO:0006826 13 12 0,000 0,03097191 0,05446683 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,03097191 0,05441491 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,03097191 0,05436308 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,03097191 0,05431136 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,03097191 0,05425973 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,03097191 0,0542082 ! collagen metabolic process GO:0032963 12 12 0,000 0,03097191 0,05415677 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,03097191 0,05410544 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,03097191 0,0540542 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,03097191 0,05400306 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,03097191 0,05395202 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,03097191 0,05390107 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,03097191 0,05385022 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,03097191 0,05379947 ! actomyosin structure organization GO:0031032 12 12 0,000 0,03097191 0,05374881 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,03097191 0,05369825 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,03097191 0,05364778 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,03097191 0,0535974 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,03097191 0,05354713 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,03097191 0,05349694 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,03097191 0,05344685 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,03097191 0,05339685 ! vacuolar transport GO:0007034 12 12 0,000 0,03097191 0,05334695 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,03097191 0,05329714 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,03097191 0,05324742 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,03097191 0,0531978 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,03097191 0,05314826 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,03097191 0,05309882 ! male gonad development GO:0008584 12 12 0,000 0,03097191 0,05304948 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,03097191 0,05300022 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,03097191 0,05295105 ! renal system process GO:0003014 12 12 0,000 0,03097191 0,05290198 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,03097191 0,052853 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,03097191 0,0528041 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,03097191 0,0527553 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,03097191 0,05270659 ! pallium development GO:0021543 13 12 0,000 0,03097191 0,05265797 ! cell fate determination GO:0001709 12 12 0,000 0,03097191 0,05260943 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,03097191 0,05256099 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,03097191 0,05251264 ! somitogenesis GO:0001756 13 12 0,000 0,03097191 0,05246437 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,03097191 0,05241619 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,03097191 0,05236811 ! detection of light stimulus GO:0009583 13 12 0,000 0,03097191 0,05232011 ! synaptogenesis GO:0007416 12 12 0,000 0,03097191 0,05227219 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,03097191 0,05222437 ! hormone transport GO:0009914 12 12 0,000 0,03097191 0,05217663 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,03097191 0,05212898 ! heme biosynthetic process GO:0006783 12 12 0,000 0,03097191 0,05208142 ! spermatid differentiation GO:0048515 13 12 0,000 0,03097191 0,05203394 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,03097191 0,05198655 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,03097191 0,05193925 ! neural tube closure GO:0001843 13 12 0,000 0,03097191 0,05189203 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,03097191 0,0518449 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,03097191 0,05179785 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,03351159 0,05599443 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,03351159 0,05594372 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,03351159 0,05589309 ! phenol metabolic process GO:0018958 13 13 0,000 0,03351159 0,05584255 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,03351159 0,05579211 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,03351159 0,05574175 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,03351159 0,05569149 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,03351159 0,05564132 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,03351159 0,05559123 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,03351159 0,05554124 ! regeneration GO:0031099 13 13 0,000 0,03351159 0,05549134 ! keratinization GO:0031424 13 13 0,000 0,03351159 0,05544153 ! post-embryonic development GO:0009791 14 13 0,000 0,03351159 0,0553918 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,03351159 0,05534217 ! patterning of blood vessels GO:0001569 13 13 0,000 0,03351159 0,05529262 ! vasculogenesis GO:0001570 13 13 0,000 0,03351159 0,05524317 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,03351159 0,0551938 ! regulation of innate immune response GO:0045088 13 13 0,000 0,03351159 0,05514452 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,03351159 0,05509533 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,03351159 0,05504622 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,03351159 0,05499721 ! autophagy GO:0006914 13 13 0,000 0,03351159 0,05494828 ! receptor metabolic process GO:0043112 14 13 0,000 0,03351159 0,05489943 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,03351159 0,05485068 ! ureteric bud development GO:0001657 13 13 0,000 0,03351159 0,05480201 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,03351159 0,05475342 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,03351159 0,05470493 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,03351159 0,05465651 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,03351159 0,05460819 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,03351159 0,05455995 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,03351159 0,05451179 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,03351159 0,05446372 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,03351159 0,05441574 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,03351159 0,05436784 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,03351159 0,05432002 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,03351159 0,05427229 ! vasodilation GO:0042311 14 13 0,000 0,03351159 0,05422464 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,03351159 0,05417707 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,03351159 0,05412959 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,03351159 0,05408219 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,03351159 0,05403487 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,03351159 0,05398764 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,03351159 0,05394049 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,03351159 0,05389342 ! immunoglobulin production GO:0002377 13 13 0,000 0,03351159 0,05384644 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,03351159 0,05379953 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,03351159 0,05375271 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,03351159 0,05370597 ! cell-cell junction organization GO:0045216 13 13 0,000 0,03351159 0,05365931 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,03351159 0,05361273 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,03351159 0,05356623 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,03351159 0,05351981 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,03351159 0,05347347 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,03351159 0,05342722 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,03351159 0,05338104 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,03351159 0,05333494 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,03351159 0,05328892 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,03351159 0,05324298 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,03351159 0,05319712 ! blastocyst development GO:0001824 13 13 0,000 0,03351159 0,05315134 ! telomere organization GO:0032200 13 13 0,000 0,03351159 0,05310564 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,03351159 0,05306002 ! regulation of amine transport GO:0051952 13 13 0,000 0,03351159 0,05301447 ! tissue homeostasis GO:0001894 13 13 0,000 0,03351159 0,05296901 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,03351159 0,05292362 ! neuron fate commitment GO:0048663 14 14 0,000 0,03604498 0,05687577 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,03604498 0,05682712 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,03604498 0,05677855 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,03604498 0,05673006 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,03604498 0,05668166 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,03604498 0,05663333 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,03604498 0,05658509 ! protein amino acid acylation GO:0043543 14 14 0,000 0,03604498 0,05653694 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,03604498 0,05648886 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,03604498 0,05644087 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,03604498 0,05639295 ! vesicle docking GO:0048278 14 14 0,000 0,03604498 0,05634512 ! superoxide metabolic process GO:0006801 15 14 0,000 0,03604498 0,05629737 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,03604498 0,0562497 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,03604498 0,05620212 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,03604498 0,05615461 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,03604498 0,05610718 ! hair cycle GO:0042633 14 14 0,000 0,03604498 0,05605983 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,03604498 0,05601256 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,03604498 0,05596537 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,03604498 0,05591827 ! lysosome organization GO:0007040 14 14 0,000 0,03604498 0,05587124 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,03604498 0,05582429 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,03604498 0,05577741 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,03604498 0,05573062 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,03604498 0,05568391 ! primary neural tube formation GO:0014020 15 14 0,000 0,03604498 0,05563727 ! peptide cross-linking GO:0018149 14 14 0,000 0,03604498 0,05559071 ! regulation of behavior GO:0050795 14 14 0,000 0,03604498 0,05554423 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,03604498 0,05549783 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,03604498 0,0554515 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,03604498 0,05540525 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,03604498 0,05535908 ! formation of primary germ layer GO:0001704 14 14 0,000 0,03604498 0,05531299 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,03604498 0,05526697 ! collagen fibril organization GO:0030199 14 14 0,000 0,03604498 0,05522103 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,03604498 0,05517517 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,03604498 0,05512938 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,03604498 0,05508367 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,03604498 0,05503803 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,03604498 0,05499247 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,03604498 0,05494698 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,03604498 0,05490157 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,03604498 0,05485623 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,0385721 0,05865378 ! positive regulation of ossification GO:0045778 15 15 0,000 0,0385721 0,05860542 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,0385721 0,05855715 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,0385721 0,05850895 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,0385721 0,05846084 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,0385721 0,0584128 ! response to vitamin GO:0033273 15 15 0,000 0,0385721 0,05836484 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,0385721 0,05831696 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,0385721 0,05826916 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,0385721 0,05822144 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,0385721 0,0581738 ! ovarian follicle development GO:0001541 15 15 0,000 0,0385721 0,05812623 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,0385721 0,05807874 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,0385721 0,05803133 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,0385721 0,057984 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,0385721 0,05793674 ! heme metabolic process GO:0042168 15 15 0,000 0,0385721 0,05788956 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,0385721 0,05784246 ! chromosome condensation GO:0030261 15 15 0,000 0,0385721 0,05779543 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,0385721 0,05774848 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,0385721 0,05770161 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,0385721 0,05765481 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,0385721 0,05760809 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,0385721 0,05756144 ! phospholipid transport GO:0015914 15 15 0,000 0,0385721 0,05751487 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,0385721 0,05746837 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,0385721 0,05742195 ! glutathione metabolic process GO:0006749 16 15 0,000 0,0385721 0,05737561 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,0385721 0,05732934 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,0385721 0,05728314 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,0385721 0,05723702 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,0385721 0,05719097 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,0385721 0,057145 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,0385721 0,0570991 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,0385721 0,05705327 ! protein homooligomerization GO:0051260 15 15 0,000 0,0385721 0,05700752 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,0385721 0,05696184 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,04109296 0,06063597 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,04109296 0,06058746 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,04109296 0,06053903 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,04109296 0,06049067 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,04109296 0,0604424 ! learning GO:0007612 16 16 0,000 0,04109296 0,0603942 ! circadian rhythm GO:0007623 16 16 0,000 0,04109296 0,06034607 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,04109296 0,06029803 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,04109296 0,06025006 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,04109296 0,06020216 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,04109296 0,06015435 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,04109296 0,06010661 ! vesicle targeting GO:0006903 17 16 0,000 0,04109296 0,06005894 ! segmentation GO:0035282 17 16 0,000 0,04109296 0,06001135 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,04109296 0,05996383 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,04109296 0,05991639 ! iron ion homeostasis GO:0055072 16 16 0,000 0,04109296 0,05986903 ! positive regulation of cell development GO:0010720 16 16 0,000 0,04109296 0,05982174 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,04109296 0,05977452 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,04109296 0,05972738 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,04109296 0,05968032 ! cell fate specification GO:0001708 16 16 0,000 0,04109296 0,05963332 ! pentose metabolic process GO:0019321 16 16 0,000 0,04109296 0,05958641 ! fatty acid transport GO:0015908 16 16 0,000 0,04109296 0,05953956 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,04109296 0,05949279 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,04109296 0,05944609 ! cofactor catabolic process GO:0051187 16 16 0,000 0,04109296 0,05939947 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,04109296 0,05935292 ! polyol metabolic process GO:0019751 16 16 0,000 0,04109296 0,05930644 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,04109296 0,05926003 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,04109296 0,0592137 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,04109296 0,05916744 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,04109296 0,05912125 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,04109296 0,05907513 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,04109296 0,05902909 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,04109296 0,05898312 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,04360757 0,06254378 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,04360757 0,06249515 ! myelination GO:0042552 17 17 0,000 0,04360757 0,06244659 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,04360757 0,06239811 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,04360757 0,0623497 ! leukocyte adhesion GO:0007159 17 17 0,000 0,04360757 0,06230136 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,04360757 0,06225311 ! sensory perception of smell GO:0007608 17 17 0,000 0,04360757 0,06220492 ! glucose transport GO:0015758 17 17 0,000 0,04360757 0,06215681 ! cell junction assembly GO:0034329 18 17 0,000 0,04360757 0,06210878 ! tissue remodeling GO:0048771 17 17 0,000 0,04360757 0,06206082 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,04360757 0,06201293 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,04360757 0,06196512 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,04360757 0,06191738 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,04360757 0,06186972 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,04360757 0,06182212 ! neural crest cell development GO:0014032 19 17 0,000 0,04360757 0,0617746 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,04360757 0,06172716 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,04360757 0,06167979 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,04360757 0,06163249 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,04360757 0,06158526 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,04360757 0,0615381 ! pigmentation GO:0043473 17 17 0,000 0,04360757 0,06149102 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,04360757 0,06144401 ! adult locomotory behavior GO:0008344 17 17 0,000 0,04360757 0,06139707 ! embryonic organ development GO:0048568 17 17 0,000 0,04360757 0,0613502 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,04360757 0,0613034 ! liver development GO:0001889 17 17 0,000 0,04360757 0,06125668 ! gene silencing GO:0016458 17 17 0,000 0,04360757 0,06121002 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,04611596 0,06468167 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,04611596 0,06463249 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,04611596 0,06458337 ! meiosis I GO:0007127 18 18 0,000 0,04611596 0,06453433 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,04611596 0,06448537 ! membrane docking GO:0022406 18 18 0,000 0,04611596 0,06443648 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,04611596 0,06438767 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,04611596 0,06433892 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,04611596 0,06429026 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,04611596 0,06424166 ! hexose transport GO:0008645 18 18 0,000 0,04611596 0,06419314 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,04611596 0,06414469 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,04611596 0,06409632 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,04611596 0,06404802 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,04611596 0,06399979 ! ceramide metabolic process GO:0006672 18 18 0,000 0,04611596 0,06395163 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,04611596 0,06390355 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,04611596 0,06385554 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,04611596 0,0638076 ! ensheathment of neurons GO:0007272 18 18 0,000 0,04611596 0,06375973 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,04611596 0,06371193 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,04611596 0,06366421 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,04611596 0,06361656 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,04611596 0,06356897 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,04861814 0,06696803 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,04861814 0,06691802 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,04861814 0,06686808 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,04861814 0,06681821 ! feeding behavior GO:0007631 19 19 0,000 0,04861814 0,06676842 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,04861814 0,06671871 ! peroxisome organization GO:0007031 19 19 0,000 0,04861814 0,06666907 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,04861814 0,0666195 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,04861814 0,06657 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,04861814 0,06652058 ! metanephros development GO:0001656 19 19 0,000 0,04861814 0,06647123 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,04861814 0,06642196 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,04861814 0,06637276 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,04861814 0,06632363 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,04861814 0,06627457 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,04861814 0,06622559 ! peripheral nervous system development GO:0007422 19 19 0,000 0,04861814 0,06617668 ! regulation of protein stability GO:0031647 19 19 0,000 0,04861814 0,06612784 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,04861814 0,06607907 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,04861814 0,06603038 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,04861814 0,06598176 ! eye morphogenesis GO:0048592 19 19 0,000 0,04861814 0,0659332 ! regulation of cell shape GO:0008360 21 19 0,000 0,04861814 0,06588472 ! placenta development GO:0001890 19 19 0,000 0,04861814 0,06583631 ! response to heat GO:0009408 19 19 0,000 0,04861814 0,06578798 ! vesicle localization GO:0051648 20 19 0,000 0,04861814 0,06573971 ! regulation of muscle development GO:0048634 21 20 0,000 0,05111411 0,06906401 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,05111411 0,06901341 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,05111411 0,06896289 ! negative regulation of binding GO:0051100 21 20 0,000 0,05111411 0,06891244 ! organic ether metabolic process GO:0018904 20 20 0,000 0,05111411 0,06886206 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,05111411 0,06881176 ! neural tube development GO:0021915 21 20 0,000 0,05111411 0,06876154 ! nucleus organization GO:0006997 20 20 0,000 0,05111411 0,06871138 ! phagocytosis GO:0006909 21 20 0,000 0,05111411 0,0686613 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,05111411 0,06861129 ! protein targeting to membrane GO:0006612 22 20 0,000 0,05111411 0,06856136 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,05111411 0,06851149 ! chromatin remodeling GO:0006338 20 20 0,000 0,05111411 0,0684617 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,05111411 0,06841198 ! lipid oxidation GO:0034440 20 20 0,000 0,05111411 0,06836234 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,05111411 0,06831277 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,05111411 0,06826326 ! RNA modification GO:0009451 20 20 0,000 0,05111411 0,06821383 ! single fertilization GO:0007338 21 20 0,000 0,05111411 0,06816447 ! regulation of B cell activation GO:0050864 20 20 0,000 0,05111411 0,06811519 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,0536039 0,07138149 ! mRNA catabolic process GO:0006402 21 21 0,000 0,0536039 0,07132995 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,0536039 0,07127849 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,0536039 0,0712271 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,0536039 0,07117578 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,0536039 0,07112454 ! Notch signaling pathway GO:0007219 22 21 0,000 0,0536039 0,07107337 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,0536039 0,07102227 ! ear morphogenesis GO:0042471 21 21 0,000 0,0536039 0,07097125 ! organic anion transport GO:0015711 21 21 0,000 0,0536039 0,0709203 ! cholesterol transport GO:0030301 21 21 0,000 0,0536039 0,07086943 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,0536039 0,07081863 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,0536039 0,0707679 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,0536039 0,07071724 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,0536039 0,07066665 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,0536039 0,07061614 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,0536039 0,0705657 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,0536039 0,07051533 ! regulation of proteolysis GO:0030162 21 21 0,000 0,0536039 0,07046504 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,0536039 0,07041481 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,0536039 0,07036466 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,05608751 0,07357245 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,05608751 0,07352012 ! sister chromatid segregation GO:0000819 22 22 0,000 0,05608751 0,07346787 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,05608751 0,07341569 ! regulation of ion transport GO:0043269 22 22 0,000 0,05608751 0,07336358 ! odontogenesis GO:0042476 22 22 0,000 0,05608751 0,07331155 ! cell junction organization GO:0034330 23 22 0,000 0,05608751 0,0732596 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,05608751 0,07320771 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,05608751 0,0731559 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,05608751 0,07310416 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,05608751 0,0730525 ! ovulation cycle process GO:0022602 22 22 0,000 0,05608751 0,07300091 ! spindle organization GO:0007051 22 22 0,000 0,05608751 0,07294939 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,05608751 0,07289795 ! cell chemotaxis GO:0060326 23 22 0,000 0,05608751 0,07284657 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,05608751 0,07279527 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,05608751 0,07274405 ! male sex differentiation GO:0046661 22 22 0,000 0,05608751 0,07269289 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,05608751 0,07264181 ! biopolymer methylation GO:0043414 22 22 0,000 0,05608751 0,07259079 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,05608751 0,07253985 ! detection of external stimulus GO:0009581 23 22 0,000 0,05608751 0,07248898 ! neuron migration GO:0001764 22 22 0,000 0,05608751 0,07243818 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,05608751 0,07238746 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,05608751 0,0723368 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,05608751 0,07228622 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,05608751 0,0722357 ! aerobic respiration GO:0009060 22 22 0,000 0,05608751 0,07218526 ! cytokine production GO:0001816 22 22 0,000 0,05608751 0,07213488 ! cytokinesis GO:0000910 23 22 0,000 0,05608751 0,07208458 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,05608751 0,07203435 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,05856497 0,07516382 ! viral infectious cycle GO:0019058 23 23 0,000 0,05856497 0,07511152 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,05856497 0,07505928 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,05856497 0,07500712 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,05856497 0,07495503 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,05856497 0,07490302 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,05856497 0,07485107 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,05856497 0,0747992 ! endocrine system development GO:0035270 23 23 0,000 0,05856497 0,0747474 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,05856497 0,07469567 ! female gonad development GO:0008585 23 23 0,000 0,05856497 0,07464402 ! lipid homeostasis GO:0055088 23 23 0,000 0,05856497 0,07459243 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,05856497 0,07454092 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,05856497 0,07448947 ! cell projection assembly GO:0030031 25 23 0,000 0,05856497 0,0744381 ! regulation of action potential GO:0001508 24 24 0,000 0,06103629 0,07752577 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,06103629 0,07747237 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,06103629 0,07741906 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,06103629 0,07736581 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,06103629 0,07731264 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,06103629 0,07725954 ! ovulation cycle GO:0042698 24 24 0,000 0,06103629 0,07720651 ! fertilization GO:0009566 25 24 0,000 0,06103629 0,07715356 ! maintenance of protein location GO:0045185 25 24 0,000 0,06103629 0,07710068 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,06103629 0,07704787 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,06103629 0,07699513 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,06103629 0,07694247 ! glucan metabolic process GO:0044042 25 24 0,000 0,06103629 0,07688988 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,06350148 0,07994073 ! negative regulation of secretion GO:0051048 26 25 0,000 0,06350148 0,07988617 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,06350148 0,07983167 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,06350148 0,07977726 ! cellular component disassembly GO:0022411 26 25 0,000 0,06350148 0,07972291 ! endosome transport GO:0016197 25 25 0,000 0,06350148 0,07966864 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,06350148 0,07961445 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,06350148 0,07956032 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,06350148 0,07950627 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,06350148 0,0794523 ! excretion GO:0007588 25 25 0,000 0,06350148 0,0793984 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,06350148 0,07934457 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,06350148 0,07929081 ! gastrulation GO:0007369 25 25 0,000 0,06350148 0,07923713 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,06350148 0,07918351 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,06350148 0,07912998 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,06350148 0,07907651 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,06350148 0,07902312 ! positive regulation of binding GO:0051099 27 26 0,000 0,06596056 0,08202788 ! positive regulation of defense response GO:0031349 26 26 0,000 0,06596056 0,08197256 ! glycolysis GO:0006096 26 26 0,000 0,06596056 0,08191733 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,06596056 0,08186216 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,06596056 0,08180708 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,06596056 0,08175206 ! cellular defense response GO:0006968 26 26 0,000 0,06596056 0,08169712 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,06596056 0,08164225 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,06596056 0,08158746 ! regulation of protein secretion GO:0050708 26 26 0,000 0,06596056 0,08153274 ! germ cell development GO:0007281 27 26 0,000 0,06596056 0,08147809 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,06596056 0,08142352 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,06596056 0,08136902 ! maintenance of location in cell GO:0051651 27 26 0,000 0,06596056 0,08131459 ! synapse organization GO:0050808 26 26 0,000 0,06596056 0,08126024 ! chloride transport GO:0006821 27 27 0,000 0,06841354 0,08422589 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,06841354 0,08416966 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,06841354 0,08411351 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,06841354 0,08405743 ! learning or memory GO:0007611 28 27 0,000 0,06841354 0,08400143 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,06841354 0,08394551 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,06841354 0,08388966 ! peptide metabolic process GO:0006518 29 27 0,000 0,06841354 0,08383388 ! mesenchymal cell development GO:0014031 29 27 0,000 0,06841354 0,08377817 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,06841354 0,08372254 ! defense response to bacterium GO:0042742 27 27 0,000 0,06841354 0,08366699 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,06841354 0,08361151 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,06841354 0,0835561 ! cell growth GO:0016049 27 27 0,000 0,06841354 0,08350076 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,07086043 0,08643003 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,07086043 0,08637287 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,07086043 0,08631578 ! carbohydrate transport GO:0008643 28 28 0,000 0,07086043 0,08625877 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,07086043 0,08620183 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,07086043 0,08614497 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,07086043 0,08608818 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,07086043 0,08603147 ! histone modification GO:0016570 28 28 0,000 0,07086043 0,08597484 ! developmental growth GO:0048589 28 28 0,000 0,07086043 0,08591827 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,07086043 0,08586179 ! cartilage development GO:0051216 29 28 0,000 0,07086043 0,08580537 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,07330125 0,0887027 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,07330125 0,08864449 ! leukocyte migration GO:0050900 30 29 0,000 0,07330125 0,08858637 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,07330125 0,08852832 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,07330125 0,08847034 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,07330125 0,08841244 ! tRNA processing GO:0008033 29 29 0,000 0,07330125 0,08835462 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,07330125 0,08829687 ! covalent chromatin modification GO:0016569 29 29 0,000 0,07330125 0,0882392 ! adult behavior GO:0030534 30 29 0,000 0,07330125 0,0881816 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,07330125 0,08812408 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,07330125 0,08806663 ! transition metal ion transport GO:0000041 31 30 0,000 0,07573602 0,09093256 ! RNA catabolic process GO:0006401 30 30 0,000 0,07573602 0,09087336 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,07573602 0,09081424 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,07573602 0,09075519 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,07573602 0,09069622 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,07573602 0,09063733 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,07573602 0,09057851 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,07573602 0,09051977 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,07573602 0,0904611 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,07573602 0,09040251 ! response to temperature stimulus GO:0009266 30 30 0,000 0,07573602 0,090344 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,07573602 0,09028556 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,07573602 0,0902272 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,07573602 0,09016892 ! vesicle organization GO:0016050 30 30 0,000 0,07573602 0,09011071 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,07573602 0,09005257 ! establishment of organelle localization GO:0051656 31 30 0,000 0,07573602 0,08999451 ! regulation of translational initiation GO:0006446 31 31 0,000 0,07816474 0,09282063 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,07816474 0,09276086 ! membrane fusion GO:0006944 31 31 0,000 0,07816474 0,09270117 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,07816474 0,09264156 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,07816474 0,09258202 ! ion transmembrane transport GO:0034220 31 31 0,000 0,07816474 0,09252256 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,07816474 0,09246317 ! digestion GO:0007586 31 31 0,000 0,07816474 0,09240386 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,07816474 0,09234463 ! regulation of heart contraction GO:0008016 31 31 0,000 0,07816474 0,09228547 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,07816474 0,09222639 ! camera-type eye development GO:0043010 31 31 0,000 0,07816474 0,09216738 ! extracellular matrix organization GO:0030198 31 31 0,000 0,07816474 0,09210845 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,07816474 0,0920496 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,07816474 0,09199082 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,07816474 0,09193211 ! cell redox homeostasis GO:0045454 32 32 0,000 0,08058744 0,09472107 ! muscle fiber development GO:0048747 32 32 0,000 0,08058744 0,0946607 ! glucose catabolic process GO:0006007 32 32 0,000 0,08058744 0,09460041 ! lipid modification GO:0030258 32 32 0,000 0,08058744 0,09454019 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,08058744 0,09448005 ! nuclear export GO:0051168 32 32 0,000 0,08058744 0,09441999 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,08058744 0,09436 ! kidney development GO:0001822 32 32 0,000 0,08058744 0,09430009 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,08058744 0,09424026 ! maintenance of location GO:0051235 33 32 0,000 0,08058744 0,0941805 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,08300412 0,09694334 ! amino acid transport GO:0006865 33 33 0,000 0,08300412 0,09688194 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,08300412 0,09682062 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,08300412 0,09675938 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,08300412 0,09669822 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,08300412 0,09663714 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,08300412 0,09657613 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,08300412 0,0965152 ! regulation of actin filament length GO:0030832 34 34 0,000 0,0854148 0,09925566 ! response to metal ion GO:0010038 34 34 0,000 0,0854148 0,09919311 ! ear development GO:0043583 34 34 0,000 0,0854148 0,09913065 ! muscle cell differentiation GO:0042692 35 34 0,000 0,0854148 0,09906826 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,0854148 0,09900596 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,0854148 0,09894373 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,0854148 0,09888158 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,0854148 0,0988195 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,0854148 0,09875751 ! secondary metabolic process GO:0019748 34 34 0,000 0,0854148 0,09869559 ! detection of stimulus GO:0051606 36 34 0,000 0,0854148 0,09863375 ! regulation of cellular component size GO:0032535 35 35 0,000 0,08781949 0,1013471 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,08781949 0,10128368 ! mesoderm development GO:0007498 35 35 0,000 0,08781949 0,10122034 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,08781949 0,10115708 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,08781949 0,10109389 ! inorganic anion transport GO:0015698 35 35 0,000 0,08781949 0,10103079 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,08781949 0,10096776 ! regulation of immune effector process GO:0002697 35 35 0,000 0,08781949 0,10090481 ! hydrogen transport GO:0006818 36 36 0,000 0,09021821 0,10359636 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,09021821 0,10353186 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,09021821 0,10346743 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,09021821 0,10340309 ! regulation of mitosis GO:0007088 37 36 0,000 0,09021821 0,10333882 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,09021821 0,10327464 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,09021821 0,10321053 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,09021821 0,1031465 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,09021821 0,10308256 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,09021821 0,10301869 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,09021821 0,1029549 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,09021821 0,10289119 ! gonad development GO:0008406 36 36 0,000 0,09021821 0,10282756 ! activation of immune response GO:0002253 36 36 0,000 0,09021821 0,10276401 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,09261098 0,10542435 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,09261098 0,10535928 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,09261098 0,10529428 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,09261098 0,10522936 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,09261098 0,10516453 ! eye development GO:0001654 37 37 0,000 0,09261098 0,10509977 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,09261098 0,10503509 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,09261098 0,1049705 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,09261098 0,10490598 ! adaptive immune response GO:0002250 37 37 0,000 0,09261098 0,10484154 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,09499779 0,10747755 ! neurotransmitter transport GO:0006836 40 38 0,000 0,09499779 0,10741162 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,09499779 0,10734576 ! exocytosis GO:0006887 40 38 0,000 0,09499779 0,10727998 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,09499779 0,10721429 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,09499779 0,10714867 ! chromosome segregation GO:0007059 38 38 0,000 0,09499779 0,10708314 ! hexose catabolic process GO:0019320 38 38 0,000 0,09499779 0,10701769 ! RNA elongation GO:0006354 38 38 0,000 0,09499779 0,10695231 ! meiotic cell cycle GO:0051321 38 38 0,000 0,09499779 0,10688702 ! axon guidance GO:0007411 39 38 0,000 0,09499779 0,1068218 ! regulation of neurological system process GO:0031644 38 38 0,000 0,09499779 0,10675667 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,09499779 0,10669161 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,09737868 0,10929897 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,09737868 0,10923245 ! response to unfolded protein GO:0006986 39 39 0,000 0,09737868 0,109166 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,09737868 0,10909964 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,09737868 0,10903336 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,09737868 0,10896716 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,09737868 0,10890104 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,09737868 0,108835 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,09737868 0,10876904 ! limb development GO:0060173 39 39 0,000 0,09737868 0,10870316 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,09975365 0,11128692 ! DNA catabolic process GO:0006308 41 40 0,000 0,09975365 0,11121959 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,09975365 0,11115235 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,09975365 0,11108519 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,09975365 0,11101811 ! organelle localization GO:0051640 41 40 0,000 0,09975365 0,11095111 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,10212272 0,1135176 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,10212272 0,11344917 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,10212272 0,11338083 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,10212272 0,11331257 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,10212272 0,11324439 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,10212272 0,1131763 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,10212272 0,11310828 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,1044859 0,11565617 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,1044859 0,11558675 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,1044859 0,11551741 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,1044859 0,11544815 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,1044859 0,11537898 ! protein ubiquitination GO:0016567 43 42 0,000 0,1044859 0,11530989 ! response to protein stimulus GO:0051789 42 42 0,000 0,1044859 0,11524089 ! forebrain development GO:0030900 43 42 0,000 0,1044859 0,11517196 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,1044859 0,11510312 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,10684321 0,11762965 ! alcohol catabolic process GO:0046164 43 43 0,000 0,10684321 0,11755942 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,10684321 0,11748928 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,10684321 0,11741922 ! humoral immune response GO:0006959 44 44 0,000 0,10919465 0,11993191 ! mRNA transport GO:0051028 44 44 0,000 0,10919465 0,11986048 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,10919465 0,11978914 ! vitamin metabolic process GO:0006766 44 44 0,000 0,10919465 0,11971787 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,10919465 0,1196467 ! amine biosynthetic process GO:0009309 46 45 0,000 0,11154025 0,1221442 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,11154025 0,12207166 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,11154025 0,12199922 ! regulation of DNA binding GO:0051101 47 45 0,000 0,11154025 0,12192686 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,11154025 0,12185458 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,11154025 0,12178239 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,11154025 0,12171029 ! protein processing GO:0016485 45 45 0,000 0,11154025 0,12163827 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,11388001 0,12411642 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,11388001 0,12404306 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,11388001 0,12396979 ! regulation of membrane potential GO:0042391 46 46 0,000 0,11388001 0,12389661 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,11621395 0,12636125 ! regulation of blood pressure GO:0008217 48 47 0,000 0,11621395 0,12628674 ! sex differentiation GO:0007548 47 47 0,000 0,11621395 0,12621233 ! amine transport GO:0015837 47 47 0,000 0,11621395 0,126138 ! rhythmic process GO:0048511 47 47 0,000 0,11621395 0,12606375 ! calcium ion transport GO:0006816 48 48 0,000 0,11854209 0,12851357 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,11854209 0,12843802 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,11854209 0,12836256 ! DNA recombination GO:0006310 48 48 0,000 0,11854209 0,12828718 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,12086443 0,13072368 ! divalent metal ion transport GO:0070838 49 49 0,000 0,12086443 0,13064701 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,12086443 0,13057043 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,12086443 0,13049394 ! response to bacterium GO:0009617 50 49 0,000 0,12086443 0,13041753 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,12086443 0,13034122 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,12086443 0,130265 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of transport GO:0051051 51 50 0,000 0,12318099 0,13268415 ! chromatin assembly GO:0031497 50 50 0,000 0,12318099 0,13260664 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,12318099 0,13252923 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,12318099 0,13245191 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,12318099 0,13237468 ! transcription initiation GO:0006352 50 50 0,000 0,12318099 0,13229754 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,12318099 0,13222049 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,12318099 0,13214352 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,12549179 0,13454414 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,12549179 0,13446591 ! positive regulation of immune response GO:0050778 51 51 0,000 0,12549179 0,13438778 ! rRNA metabolic process GO:0016072 51 51 0,000 0,12549179 0,13430974 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,12549179 0,13423179 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,12549179 0,13415393 ! protein maturation GO:0051604 51 51 0,000 0,12549179 0,13407616 ! RNA localization GO:0006403 52 52 0,000 0,12779684 0,13645977 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,12779684 0,13638076 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,12779684 0,13630183 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,12779684 0,136223 ! sodium ion transport GO:0006814 53 53 0,000 0,13009614 0,13859375 ! tRNA metabolic process GO:0006399 53 53 0,000 0,13009614 0,13851368 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,13009614 0,13843371 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,13009614 0,13835383 ! regulation of T cell activation GO:0050863 53 53 0,000 0,13009614 0,13827404 ! regulation of protein transport GO:0051223 53 53 0,000 0,13009614 0,13819434 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,13238972 0,14054969 ! response to virus GO:0009615 54 54 0,000 0,13238972 0,14046877 ! sulfur metabolic process GO:0006790 55 54 0,000 0,13238972 0,14038795 ! nucleosome organization GO:0034728 55 55 0,000 0,13467759 0,14273191 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,13467759 0,14264988 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,13467759 0,14256795 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,13467759 0,14248611 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,13695976 0,14481746 ! extracellular structure organization GO:0043062 56 56 0,000 0,13695976 0,14473442 ! regulation of binding GO:0051098 60 57 0,000 0,13923624 0,14705581 ! ATP metabolic process GO:0046034 57 57 0,000 0,13923624 0,14697159 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,13923624 0,14688746 ! regulation of protein localization GO:0032880 58 57 0,000 0,13923624 0,14680343 ! innate immune response GO:0045087 58 58 0,000 0,14150705 0,14911235 ! dephosphorylation GO:0016311 60 59 0,000 0,14377221 0,15141267 ! carboxylic acid transport GO:0046942 59 59 0,000 0,14377221 0,1513262 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,14377221 0,15123983 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,14377221 0,15115355 ! immune effector process GO:0002252 59 59 0,000 0,14377221 0,15106737 ! potassium ion transport GO:0006813 60 60 0,000 0,14603171 0,1533541 ! protein polymerization GO:0051258 65 60 0,000 0,14603171 0,15326677 ! cellular respiration GO:0045333 62 61 0,000 0,14828559 0,15554373 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,14828559 0,15545526 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,14828559 0,15536688 ! lipid transport GO:0006869 62 62 0,000 0,15053384 0,15763288 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,15053384 0,15754337 ! axonogenesis GO:0007409 66 62 0,000 0,15053384 0,15745396 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,15053384 0,15736465 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,15053384 0,15727544 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,15053384 0,15718633 ! regulation of secretion GO:0051046 65 63 0,000 0,1527765 0,15943776 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,1527765 0,15934753 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,1527765 0,1592574 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,1527765 0,15916737 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,15501355 0,16140677 ! angiogenesis GO:0001525 65 64 0,000 0,15501355 0,16131563 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,15501355 0,16122459 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,15501355 0,16113366 ! anion transport GO:0006820 65 65 0,000 0,15724503 0,1633611 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,15947094 0,16558025 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,15947094 0,16548702 ! DNA packaging GO:0006323 66 66 0,000 0,15947094 0,16539389 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,15947094 0,16530087 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,1616913 0,16750819 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,1616913 0,16741408 ! muscle contraction GO:0006936 67 67 0,000 0,1616913 0,16732008 ! striated muscle tissue development GO:0014706 69 67 0,000 0,1616913 0,16722619 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,1616913 0,1671324 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,16390612 0,16932678 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,16390612 0,16923192 ! sensory perception of sound GO:0007605 71 69 0,000 0,16611541 0,17141697 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,16611541 0,17132104 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,16611541 0,17122523 ! cell part morphogenesis GO:0032990 75 70 0,000 0,16831919 0,17339981 ! growth GO:0040007 70 70 0,000 0,16831919 0,17330294 ! muscle tissue development GO:0060537 72 70 0,000 0,16831919 0,17320618 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,16831919 0,17310952 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,17051746 0,17527255 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,17051746 0,17517485 ! ribosome biogenesis GO:0042254 71 71 0,000 0,17051746 0,17507726 ! regulation of cell activation GO:0050865 71 71 0,000 0,17051746 0,17497978 ! secretion by cell GO:0032940 75 72 0,000 0,17271025 0,17713132 ! muscle system process GO:0003012 72 72 0,000 0,17271025 0,17703281 ! sensory organ development GO:0007423 72 72 0,000 0,17271025 0,1769344 ! regulation of cytokine production GO:0001817 72 72 0,000 0,17271025 0,17683611 ! electron transport chain GO:0022900 75 74 0,000 0,17707941 0,18120897 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,17707941 0,18110841 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,17925581 0,18323264 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,17925581 0,18313107 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,18142677 0,18524628 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,18359231 0,18735361 ! microtubule-based movement GO:0007018 82 78 0,000 0,18575243 0,18945309 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,18575243 0,18934831 ! regulation of immune response GO:0050776 78 78 0,000 0,18575243 0,18924364 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,1900565 0,19352162 ! neuron projection development GO:0031175 85 80 0,000 0,1900565 0,19341476 ! lipid catabolic process GO:0016042 82 81 0,000 0,19220047 0,19548867 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,19647234 0,1997234 ! ncRNA processing GO:0034470 83 83 0,000 0,19647234 0,1996133 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,19647234 0,19950332 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,19860026 0,20155302 ! regulation of cellular localization GO:0060341 86 85 0,000 0,20072286 0,20359507 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,20072286 0,20348308 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,20072286 0,20337121 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,20072286 0,20325947 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,20284015 0,20529072 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,20705885 0,20944537 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,20705885 0,20933048 ! chemotaxis GO:0006935 90 89 0,000 0,20916029 0,21133904 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,21125646 0,21334009 ! brain development GO:0007420 91 90 0,000 0,21125646 0,21322325 ! DNA replication GO:0006260 91 91 0,000 0,21334739 0,21521578 ! visual perception GO:0007601 93 92 0,000 0,21543308 0,21720085 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,21543308 0,2170821 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,21543308 0,21696347 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,21543308 0,21684498 ! blood vessel development GO:0001568 95 94 0,000 0,2195888 0,22090729 ! pattern specification process GO:0007389 96 94 0,000 0,2195888 0,22078677 ! epidermis development GO:0008544 94 94 0,000 0,2195888 0,22066639 ! cofactor metabolic process GO:0051186 95 94 0,000 0,2195888 0,22054613 ! vasculature development GO:0001944 97 96 0,000 0,22372372 0,2245767 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,22783795 0,22858211 ! blood circulation GO:0008015 99 98 0,000 0,22783795 0,22845775 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,22783795 0,22833352 ! anti-apoptosis GO:0006916 100 99 0,000 0,22988733 0,23026215 ! ectoderm development GO:0007398 99 99 0,000 0,22988733 0,23013708 ! muscle organ development GO:0007517 102 100 0,000 0,23193158 0,23205749 ! response to other organism GO:0051707 101 100 0,000 0,23193158 0,23193158