pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6595-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 3,000 7,088E-10 1,732E-06 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 3,000 4,232E-09 5,169E-06 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 4,774E-08 3,887E-05 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 2,093E-07 1,278E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 2,935E-07 1,434E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 56 28 3,000 4,006E-07 1,631E-04 ! induction of positive chemotaxis GO:0050930 17 9 2,000 8,134E-07 2,839E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 1,593E-06 4,864E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 1,593E-06 4,324E-04 GO:0010829|negative regulation of glucose transport, ! regulation of positive chemotaxis GO:0050926 22 12 2,000 2,12E-06 5,18E-04 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 3,497E-06 7,767E-04 ! regulation of inflammatory response GO:0050727 84 48 3,000 3,684E-06 7,5E-04 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 4,365E-06 8,203E-04 ! response to UV GO:0009411 120 55 3,000 6,383E-06 1,114E-03 ! negative regulation of cell motion GO:0051271 142 55 3,000 6,383E-06 1,04E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 6,503E-06 9,929E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 7,791E-06 1,12E-03 ! negative regulation of response to stimulus GO:0048585 106 61 3,000 9,672E-06 1,313E-03 ! actin filament bundle formation GO:0051017 47 20 2,000 1,085E-05 1,395E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,085E-05 1,325E-03 GO:0010827|regulation of glucose transport, ! positive regulation of cell motion GO:0051272 157 65 3,000 1,247E-05 1,45E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,264E-05 1,404E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 1,264E-05 1,343E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 1,461E-05 1,487E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 1,461E-05 1,428E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 1,581E-05 1,486E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 1,581E-05 1,431E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 1,674E-05 1,461E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 1,678E-05 1,413E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 2,087E-05 1,7E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 2,172E-05 1,712E-03 ! regulation of behavior GO:0050795 48 25 2,000 2,172E-05 1,658E-03 ! protein tetramerization GO:0051262 57 25 2,000 2,172E-05 1,608E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 2,754E-05 1,979E-03 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 2,984E-05 2,083E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 3,08E-05 2,09E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 3,08E-05 2,033E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 3,285E-05 2,112E-03 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 4,206E-05 2,635E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 4,613E-05 2,817E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 4,613E-05 2,748E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 4,613E-05 2,683E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,613E-05 2,621E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 4,613E-05 2,561E-03 ! ossification GO:0001503 205 91 3,000 4,716E-05 2,56E-03 ! bone development GO:0060348 206 92 3,000 4,922E-05 2,614E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 5,089E-05 2,645E-03 GO:0060326|cell chemotaxis, ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 5,573E-05 2,836E-03 ! regulation of defense response GO:0031347 171 95 3,000 5,58E-05 2,782E-03 ! positive regulation of endocytosis GO:0045807 56 35 2,000 6,086E-05 2,974E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 6,301E-05 3,018E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 6,909E-05 3,246E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 6,909E-05 3,185E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 7,808E-05 3,532E-03 ! carbohydrate homeostasis GO:0033500 59 39 2,000 8,445E-05 3,751E-03 GO:0042593|glucose homeostasis, ! regulation of helicase activity GO:0051095 16 7 1,000 9,659E-05 4,214E-03 ! prostate gland development GO:0030850 14 7 1,000 9,659E-05 4,14E-03 ! male sex determination GO:0030238 15 7 1,000 9,659E-05 4,069E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 9,659E-05 4E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 9,659E-05 3,933E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 9,659E-05 3,868E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 1,214E-04 4,785E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,286E-04 4,987E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 1,286E-04 4,909E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,286E-04 4,834E-03 ! ER overload response GO:0006983 13 8 1,000 1,286E-04 4,761E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,286E-04 4,689E-03 ! response to tumor cell GO:0002347 16 8 1,000 1,286E-04 4,621E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,286E-04 4,554E-03 ! positive regulation of ATPase activity GO:0032781 13 8 1,000 1,286E-04 4,488E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,299E-04 4,47E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,388E-04 4,708E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,388E-04 4,643E-03 ! leukocyte migration GO:0050900 75 46 2,000 1,388E-04 4,581E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 1,48E-04 4,82E-03 ! positive regulation of defense response GO:0031349 88 48 2,000 1,576E-04 5,066E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,651E-04 5,239E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 1,651E-04 5,172E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,651E-04 5,106E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 1,78E-04 5,437E-03 ! regulation of ossification GO:0030278 123 50 2,000 1,78E-04 5,37E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 2,061E-04 6,141E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,061E-04 6,067E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,061E-04 5,994E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 2,061E-04 5,924E-03 ! epithelial cell development GO:0002064 21 10 1,000 2,061E-04 5,855E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 2,061E-04 5,788E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 2,061E-04 5,722E-03 ! positive regulation of phagocytosis GO:0050766 14 10 1,000 2,061E-04 5,658E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 2,061E-04 5,595E-03 GO:0043470|regulation of carbohydrate catabolic process, ! cartilage development GO:0051216 99 53 2,000 2,118E-04 5,686E-03 ! regulation of muscle contraction GO:0006937 94 54 2,000 2,239E-04 5,946E-03 ! regulation of DNA replication GO:0006275 105 56 2,000 2,495E-04 6,553E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,516E-04 6,538E-03 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,516E-04 6,469E-03 ! negative regulation of ossification GO:0030279 27 11 1,000 2,516E-04 6,402E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 2,516E-04 6,336E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 2,629E-04 6,554E-03 ! regulation of bone remodeling GO:0046850 143 57 2,000 2,629E-04 6,488E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 2,768E-04 6,763E-03 ! regulation of tissue remodeling GO:0034103 146 58 2,000 2,768E-04 6,696E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 3,015E-04 7,22E-03 ! virus-host interaction GO:0019048 30 12 1,000 3,015E-04 7,15E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 3,015E-04 7,081E-03 ! focal adhesion formation GO:0048041 37 12 1,000 3,015E-04 7,014E-03 ! regulation of phagocytosis GO:0050764 17 12 1,000 3,015E-04 6,948E-03 ! localization within membrane GO:0051668 26 12 1,000 3,015E-04 6,883E-03 ! regulation of endocytosis GO:0030100 104 60 2,000 3,06E-04 6,923E-03 ! regulation of heart contraction GO:0008016 123 61 2,000 3,214E-04 7,203E-03 ! response to X-ray GO:0010165 28 13 1,000 3,558E-04 7,901E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 3,558E-04 7,83E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,558E-04 7,76E-03 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 3,558E-04 7,691E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 3,703E-04 7,936E-03 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 3,703E-04 7,867E-03 ! regulation of cellular pH GO:0030641 27 14 1,000 4,145E-04 8,729E-03 ! response to gamma radiation GO:0010332 30 14 1,000 4,145E-04 8,654E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 4,145E-04 8,581E-03 ! regulation of calcium-mediated signaling GO:0050848 29 14 1,000 4,145E-04 8,509E-03 ! negative regulation of cell growth GO:0030308 142 67 2,000 4,238E-04 8,628E-03 ! negative regulation of cell size GO:0045792 144 69 2,000 4,621E-04 9,329E-03 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 4,776E-04 9,563E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 4,776E-04 9,485E-03 ! G1/S transition checkpoint GO:0031575 37 15 1,000 4,776E-04 9,409E-03 ! actin filament organization GO:0007015 167 72 2,000 5,235E-04 0,01023187 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 5,45E-04 0,01056738 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 5,45E-04 0,01048417 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! fructose metabolic process GO:0006000 25 16 1,000 5,45E-04 0,01040226 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 5,45E-04 0,01032163 ! regulation of ATPase activity GO:0043462 26 16 1,000 5,45E-04 0,01024223 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 5,45E-04 0,01016404 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 5,673E-04 0,0104988 ! regulation of vesicle-mediated transport GO:0060627 136 77 2,000 6,372E-04 0,01170353 ! protein oligomerization GO:0051259 149 79 2,000 6,867E-04 0,01251876 ! cell-substrate junction assembly GO:0007044 56 18 1,000 6,93E-04 0,0125399 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 6,93E-04 0,0124477 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 7,734E-04 0,01379121 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 7,734E-04 0,01369127 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 7,734E-04 0,01359277 ! negative regulation of transport GO:0051051 164 85 2,000 8,497E-04 0,01482711 ! negative regulation of growth GO:0045926 168 85 2,000 8,497E-04 0,01472195 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 8,497E-04 0,01461828 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 8,581E-04 0,01466002 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 8,581E-04 0,01455821 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 8,581E-04 0,01445781 ! negative regulation of translation GO:0017148 32 20 1,000 8,581E-04 0,01435878 ! lipid phosphorylation GO:0046834 43 21 1,000 9,471E-04 0,01574016 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 9,471E-04 0,01563381 ! positive regulation of protein modification process GO:0031401 156 90 2,000 1,003E-03 0,01644249 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 1,04E-03 0,0169441 ! cellular response to starvation GO:0009267 37 22 1,000 1,04E-03 0,01683188 ! cell aging GO:0007569 48 22 1,000 1,04E-03 0,01672115 ! G1 phase GO:0051318 44 22 1,000 1,04E-03 0,01661186 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,04E-03 0,01650399 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 1,103E-03 0,01737793 ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,138E-03 0,01781903 ! gluconeogenesis GO:0006094 38 23 1,000 1,138E-03 0,01770554 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 1,138E-03 0,01759347 GO:0010810|regulation of cell-substrate adhesion, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 1,138E-03 0,01748282 ! regulation of bone mineralization GO:0030500 54 23 1,000 1,138E-03 0,01737356 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 1,24E-03 0,01880884 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 1,24E-03 0,01869274 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 1,24E-03 0,01857806 ! sex determination GO:0007530 48 24 1,000 1,24E-03 0,01846478 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,24E-03 0,01835287 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 1,245E-03 0,01832238 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 1,345E-03 0,01968223 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,345E-03 0,01956507 ! regulation of transmembrane transport GO:0034762 39 25 1,000 1,345E-03 0,0194493 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,345E-03 0,0193349 ! negative regulation of DNA replication GO:0008156 45 25 1,000 1,345E-03 0,01922183 ! interaction with host GO:0051701 66 25 1,000 1,345E-03 0,01911007 ! regulation of biomineral formation GO:0070167 56 25 1,000 1,345E-03 0,01899961 ! pyruvate metabolic process GO:0006090 43 26 1,000 1,456E-03 0,02043593 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,456E-03 0,02031915 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,456E-03 0,0202037 ! negative regulation of cell development GO:0010721 83 26 1,000 1,456E-03 0,02008956 GO:0050768|negative regulation of neurogenesis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 1,456E-03 0,0199767 ! mitochondrial membrane organization GO:0007006 60 27 1,000 1,57E-03 0,02142423 ! response to starvation GO:0042594 47 27 1,000 1,57E-03 0,02130521 ! cellular response to nutrient levels GO:0031669 45 27 1,000 1,57E-03 0,0211875 ! base-excision repair GO:0006284 41 28 1,000 1,688E-03 0,02266014 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,688E-03 0,02253632 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 1,811E-03 0,02404039 ! acute-phase response GO:0006953 50 30 1,000 1,937E-03 0,02558244 ! regulation of B cell activation GO:0050864 55 30 1,000 1,937E-03 0,0254449 ! cell junction assembly GO:0034329 85 31 1,000 2,068E-03 0,02701638 ! hexose biosynthetic process GO:0019319 53 32 1,000 2,203E-03 0,02862404 ! positive regulation of catabolic process GO:0009896 72 32 1,000 2,203E-03 0,02847259 ! regulation of pH GO:0006885 56 33 1,000 2,342E-03 0,03010779 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 2,342E-03 0,02995016 ! response to ionizing radiation GO:0010212 74 33 1,000 2,342E-03 0,02979417 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 2,484E-03 0,0314482 ! DNA damage checkpoint GO:0000077 78 35 1,000 2,631E-03 0,03313577 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 2,631E-03 0,03296584 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,631E-03 0,03279765 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 2,782E-03 0,03450229 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 2,782E-03 0,03432804 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 2,937E-03 0,03605675 ! cell junction organization GO:0034330 96 37 1,000 2,937E-03 0,03587647 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 3,096E-03 0,03762848 ! DNA integrity checkpoint GO:0031570 82 38 1,000 3,096E-03 0,0374422 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 3,259E-03 0,03921675 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 3,259E-03 0,03902451 ! gliogenesis GO:0042063 91 41 1,000 3,596E-03 0,04285424 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 3,596E-03 0,04264621 ! alcohol biosynthetic process GO:0046165 65 42 1,000 3,771E-03 0,0444999 ! T cell differentiation GO:0030217 93 42 1,000 3,771E-03 0,04428595 ! epithelial cell differentiation GO:0030855 83 43 1,000 3,949E-03 0,04615939 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 3,949E-03 0,04593959 ! double-strand break repair GO:0006302 85 44 1,000 4,131E-03 0,04783214 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 4,317E-03 0,04975115 ! B cell differentiation GO:0030183 124 45 1,000 4,317E-03 0,04951758 ! negative regulation of cell migration GO:0030336 122 46 1,000 4,507E-03 0,05145447 ! positive regulation of cell cycle GO:0045787 96 48 1,000 4,899E-03 0,05566124 ! mitochondrial transport GO:0006839 94 48 1,000 4,899E-03 0,05540355 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 5,1E-03 0,05741467 ! activation of caspase activity GO:0006919 95 50 1,000 5,305E-03 0,05944947 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 5,726E-03 0,06387844 ! positive regulation of growth GO:0045927 96 53 1,000 5,943E-03 0,0659895 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 5,943E-03 0,0656909 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 5,943E-03 0,065395 ! activation of phospholipase C activity GO:0007202 110 54 1,000 6,163E-03 0,06751131 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 6,386E-03 0,06964883 ! cell maturation GO:0048469 107 55 1,000 6,386E-03 0,06933928 ! positive regulation of caspase activity GO:0043280 108 57 1,000 6,844E-03 0,07398562 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 6,844E-03 0,07365969 ! heart morphogenesis GO:0003007 105 57 1,000 6,844E-03 0,07333662 ! nucleotide-excision repair GO:0006289 91 57 1,000 6,844E-03 0,07301638 ! aging GO:0007568 112 58 1,000 7,079E-03 0,07519029 ! positive regulation of lipase activity GO:0060193 115 58 1,000 7,079E-03 0,07486479 ! lipid modification GO:0030258 112 60 1,000 7,559E-03 0,07959579 ! viral reproductive process GO:0022415 132 62 1,000 8,053E-03 0,08443624 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 8,053E-03 0,0840754 ! regulation of homeostatic process GO:0032844 148 62 1,000 8,053E-03 0,08371763 ! activation of MAPK activity GO:0000187 124 67 1,000 9,35E-03 0,09679275 ! viral reproduction GO:0016032 142 68 1,000 9,62E-03 0,09916681 ! regulation of lipase activity GO:0060191 137 68 1,000 9,62E-03 0,09875014 ! lung development GO:0030324 165 69 1,000 9,894E-03 0,1011314 ! urogenital system development GO:0001655 149 69 1,000 9,894E-03 0,10071002 ! developmental maturation GO:0021700 128 69 1,000 9,894E-03 0,10029214 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,01045079 0,10550114 ! respiratory tube development GO:0030323 171 72 1,000 0,01073442 0,10791851 ! B cell activation GO:0042113 179 72 1,000 0,01073442 0,10747622 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01078542 0,10754606 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01078542 0,10710888 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01078542 0,10667524 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01078542 0,1062451 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01078542 0,10581841 ! neuron fate determination GO:0048664 7 5 0,000 0,01078542 0,10539514 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01078542 0,10497524 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01078542 0,10455867 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01078542 0,10414539 ! polyol transport GO:0015791 12 5 0,000 0,01078542 0,10373537 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01078542 0,10332857 ! response to superoxide GO:0000303 10 5 0,000 0,01078542 0,10292494 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01078542 0,10252445 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01078542 0,10212707 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01078542 0,10173276 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01078542 0,10134148 ! female meiosis GO:0007143 10 5 0,000 0,01078542 0,1009532 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01078542 0,10056788 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01078542 0,10018549 ! hypothalamus development GO:0021854 9 5 0,000 0,01078542 0,099806 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01078542 0,09942937 ! cobalt ion transport GO:0006824 11 5 0,000 0,01078542 0,09905558 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01078542 0,09868459 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01078542 0,09831636 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01078542 0,09795087 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01078542 0,09758809 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01078542 0,09722799 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01078542 0,09687053 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01078542 0,09651569 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01078542 0,09616345 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01078542 0,09581376 ! transposition GO:0032196 9 5 0,000 0,01078542 0,09546661 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01078542 0,09512196 ! negative chemotaxis GO:0050919 16 5 0,000 0,01078542 0,0947798 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01078542 0,09444009 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01078542 0,0941028 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01078542 0,09376792 ! behavioral response to pain GO:0048266 10 5 0,000 0,01078542 0,0934354 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01078542 0,09310524 ! Notch receptor processing GO:0007220 11 5 0,000 0,01078542 0,09277741 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01078542 0,09245187 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01078542 0,09212862 ! micturition GO:0060073 9 5 0,000 0,01078542 0,09180761 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01078542 0,09148883 ! copulation GO:0007620 9 5 0,000 0,01078542 0,09117226 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01078542 0,09085788 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01078542 0,09054565 ! bioluminescence GO:0008218 9 5 0,000 0,01078542 0,09023556 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01078542 0,08992759 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01078542 0,08962171 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01078542 0,08931791 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01078542 0,08901616 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01078542 0,08871645 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01078542 0,08841874 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01078542 0,08812302 ! grooming behavior GO:0007625 6 5 0,000 0,01078542 0,08782928 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01078542 0,08753749 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01078542 0,08724763 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01078542 0,08695968 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01078542 0,08667363 ! response to protozoan GO:0001562 13 5 0,000 0,01078542 0,08638946 ! lymph vessel development GO:0001945 10 5 0,000 0,01078542 0,08610714 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01078542 0,08582666 ! endochondral ossification GO:0001958 17 5 0,000 0,01078542 0,085548 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01078542 0,08527115 ! single strand break repair GO:0000012 8 5 0,000 0,01078542 0,08499608 ! parathyroid gland development GO:0060017 14 5 0,000 0,01078542 0,08472278 ! anagen GO:0042640 7 5 0,000 0,01078542 0,08445123 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01078542 0,08418142 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01078542 0,08391333 ! cytokine secretion GO:0050663 15 5 0,000 0,01078542 0,08364693 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01078542 0,08338223 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01078542 0,08311919 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01078542 0,08285781 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01078542 0,08259807 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01078542 0,08233995 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01078542 0,08208344 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01078542 0,08182852 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01078542 0,08157518 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01078542 0,08132341 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01078542 0,08107318 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01078542 0,08082449 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01078542 0,08057732 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01078542 0,08033166 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01078542 0,08008749 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01078542 0,0798448 ! microvillus organization GO:0032528 8 5 0,000 0,01078542 0,07960358 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01078542 0,07936381 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01078542 0,07912548 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01078542 0,07888858 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01078542 0,07865309 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01078542 0,078419 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01078542 0,0781863 ! polyol catabolic process GO:0046174 9 5 0,000 0,01078542 0,07795498 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01078542 0,07772503 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01078542 0,07749642 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01078542 0,07726916 ! muscle cell migration GO:0014812 8 5 0,000 0,01078542 0,07704323 ! mitochondrial fission GO:0000266 8 5 0,000 0,01078542 0,07681861 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01078542 0,0765953 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01078542 0,07637329 ! mRNA transcription GO:0009299 10 5 0,000 0,01078542 0,07615256 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01078542 0,0759331 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01078542 0,0757149 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01078542 0,07549795 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01078542 0,07528224 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01078542 0,07506776 ! monocyte activation GO:0042117 10 5 0,000 0,01078542 0,0748545 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01078542 0,07464245 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01078542 0,07443159 ! response to food GO:0032094 6 5 0,000 0,01078542 0,07422193 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01078542 0,07401344 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01078542 0,07380612 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01078542 0,07359996 ! forebrain neuron development GO:0021884 13 5 0,000 0,01078542 0,07339494 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01078542 0,07319107 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01078542 0,07298832 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01078542 0,0727867 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01078542 0,07258618 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01078542 0,07238677 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01078542 0,07218845 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01078542 0,07199121 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01078542 0,07179505 ! lipid glycosylation GO:0030259 7 5 0,000 0,01078542 0,07159996 ! nucleobase transport GO:0015851 6 5 0,000 0,01078542 0,07140592 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01078542 0,07121293 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01078542 0,07102098 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01078542 0,07083007 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01078542 0,07064017 ! basic amino acid transport GO:0015802 12 5 0,000 0,01078542 0,07045129 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01078542 0,07026342 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01078542 0,07007655 ! actin nucleation GO:0045010 11 5 0,000 0,01078542 0,06989067 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01078542 0,06970578 ! depurination GO:0045007 5 5 0,000 0,01078542 0,06952186 ! depyrimidination GO:0045008 10 5 0,000 0,01078542 0,06933891 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01078542 0,06915691 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01078542 0,06897587 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01078542 0,06879578 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01078542 0,06861663 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01078542 0,0684384 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01078542 0,0682611 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01078542 0,06808471 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01078542 0,06790924 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01078542 0,06773466 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01078542 0,06756099 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01078542 0,06738819 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01078542 0,06721629 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01078542 0,06704525 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01078542 0,06687509 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01078542 0,06670578 ! response to arsenic GO:0046685 11 5 0,000 0,01078542 0,06653733 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01078542 0,06636973 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01078542 0,06620298 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01078542 0,06603705 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01078542 0,06587196 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01078542 0,06570769 ! response to mercury ion GO:0046689 8 5 0,000 0,01078542 0,06554424 ! response to cadmium ion GO:0046686 7 5 0,000 0,01078542 0,0653816 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01078542 0,06521976 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01078542 0,06505873 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01078542 0,06489848 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01078542 0,06473903 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01078542 0,06458035 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01078542 0,06442246 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01078542 0,06426533 ! decidualization GO:0046697 11 5 0,000 0,01078542 0,06410896 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01078542 0,06395336 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01078542 0,06379851 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01078542 0,06364441 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01078542 0,06349105 ! embryonic cleavage GO:0040016 6 5 0,000 0,01078542 0,06333842 ! peroxisome fission GO:0016559 5 5 0,000 0,01078542 0,06318653 ! histone demethylation GO:0016577 13 5 0,000 0,01078542 0,06303537 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01078542 0,06288493 ! mitotic recombination GO:0006312 9 5 0,000 0,01078542 0,0627352 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01078542 0,06258619 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01078542 0,06243788 ! metaphase plate congression GO:0051310 7 5 0,000 0,01078542 0,06229027 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01078542 0,06214336 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01078542 0,06199714 ! enteric nervous system development GO:0048484 8 5 0,000 0,01078542 0,06185161 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01078542 0,06170675 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01078542 0,06156258 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01078542 0,06141908 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01078542 0,06127624 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01078542 0,06113407 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01078542 0,06099256 ! B cell homeostasis GO:0001782 13 5 0,000 0,01078542 0,0608517 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01078542 0,06071148 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01078542 0,06057192 ! metaphase GO:0051323 11 5 0,000 0,01078542 0,06043299 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01078542 0,0602947 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01078542 0,06015704 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01078542 0,06002001 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01078542 0,0598836 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01078542 0,05974781 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01078542 0,05961263 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01078542 0,05947807 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01078542 0,05934411 ! response to redox state GO:0051775 6 5 0,000 0,01078542 0,05921075 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01078542 0,05907799 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01078542 0,05894583 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01078542 0,05881425 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01078542 0,05868326 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01078542 0,05855285 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01078542 0,05842302 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01078542 0,05829377 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01078542 0,05816509 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01078542 0,05803697 ! striatum development GO:0021756 14 5 0,000 0,01078542 0,05790942 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01078542 0,05778242 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01078542 0,05765598 ! glial cell migration GO:0008347 10 5 0,000 0,01078542 0,0575301 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01078542 0,05740476 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01078542 0,05727997 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01078542 0,05715571 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01078542 0,057032 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01078542 0,05690882 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01078542 0,05678617 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01078542 0,05666405 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01078542 0,05654246 ! neuroprotection GO:0043526 8 5 0,000 0,01078542 0,05642138 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01078542 0,05630082 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01078542 0,05618078 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01078542 0,05606124 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01078542 0,05594222 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01078542 0,0558237 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01078542 0,05570567 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01078542 0,05558815 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01078542 0,05547112 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01078542 0,05535459 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01078542 0,05523854 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01078542 0,05512298 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01078542 0,0550079 ! spindle assembly GO:0051225 6 5 0,000 0,01078542 0,0548933 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01078542 0,05477918 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01078542 0,05466553 ! protein palmitoylation GO:0018345 12 5 0,000 0,01078542 0,05455235 ! drug metabolic process GO:0017144 7 5 0,000 0,01078542 0,05443964 ! stem cell division GO:0017145 11 5 0,000 0,01078542 0,05432739 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01078542 0,05421561 ! organ regeneration GO:0031100 7 5 0,000 0,01078542 0,05410428 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01078542 0,05399341 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01078542 0,05388299 ! acute inflammatory response GO:0002526 118 74 1,000 0,01131184 0,05639761 ! regulation of caspase activity GO:0043281 136 74 1,000 0,01131184 0,05628274 ! respiratory system development GO:0060541 175 74 1,000 0,01131184 0,05616835 ! reproductive structure development GO:0048608 131 75 1,000 0,01160559 0,05751005 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,01190268 0,05886285 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,01190268 0,05874393 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01220309 0,06010516 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01220309 0,05998422 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01220309 0,05986377 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01250682 0,06123077 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01292869 0,06316957 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01292869 0,06304348 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01292869 0,06291789 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01292869 0,06279281 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01292869 0,06266822 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01292869 0,06254412 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01292869 0,06242052 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01292869 0,0622974 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01292869 0,06217477 ! response to oxygen radical GO:0000305 11 6 0,000 0,01292869 0,06205262 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01292869 0,06193095 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01292869 0,06180975 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01292869 0,06168903 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01292869 0,06156878 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01292869 0,06144899 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01292869 0,06132967 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01292869 0,06121082 ! forebrain regionalization GO:0021871 9 6 0,000 0,01292869 0,06109242 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01292869 0,06097448 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01292869 0,060857 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01292869 0,06073997 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01292869 0,06062338 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01292869 0,06050725 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01292869 0,06039155 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01292869 0,0602763 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01292869 0,06016149 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01292869 0,06004712 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01292869 0,05993317 ! malate metabolic process GO:0006108 13 6 0,000 0,01292869 0,05981966 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01292869 0,05970658 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01292869 0,05959393 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01292869 0,0594817 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01292869 0,05936989 ! protein refolding GO:0042026 15 6 0,000 0,01292869 0,0592585 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01292869 0,05914753 ! opsonization GO:0008228 8 6 0,000 0,01292869 0,05903698 ! mating behavior GO:0007617 7 6 0,000 0,01292869 0,05892683 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01292869 0,0588171 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01292869 0,05870777 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01292869 0,05859885 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01292869 0,05849034 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01292869 0,05838222 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01292869 0,05827451 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01292869 0,05816719 ! toxin metabolic process GO:0009404 11 6 0,000 0,01292869 0,05806026 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01292869 0,05795373 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01292869 0,05784759 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01292869 0,05774183 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01292869 0,05763646 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01292869 0,05753148 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01292869 0,05742688 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01292869 0,05732265 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01292869 0,05721881 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01292869 0,05711534 ! thymic T cell selection GO:0045061 16 6 0,000 0,01292869 0,05701224 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01292869 0,05690952 ! protein lipoylation GO:0009249 10 6 0,000 0,01292869 0,05680716 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01292869 0,05670518 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01292869 0,05660355 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01292869 0,05650229 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01292869 0,0564014 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01292869 0,05630086 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01292869 0,05620068 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01292869 0,05610086 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01292869 0,05600139 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01292869 0,05590227 ! hyperosmotic response GO:0006972 10 6 0,000 0,01292869 0,0558035 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01292869 0,05570508 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01292869 0,05560701 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01292869 0,05550928 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01292869 0,0554119 ! urea metabolic process GO:0019627 7 6 0,000 0,01292869 0,05531486 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01292869 0,05521815 ! neutrophil activation GO:0042119 7 6 0,000 0,01292869 0,05512178 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01292869 0,05502575 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01292869 0,05493006 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01292869 0,05483469 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01292869 0,05473966 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01292869 0,05464495 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01292869 0,05455057 ! neuron apoptosis GO:0051402 15 6 0,000 0,01292869 0,05445652 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01292869 0,05436279 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01292869 0,05426939 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01292869 0,0541763 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01292869 0,05408353 ! carnitine transport GO:0015879 10 6 0,000 0,01292869 0,05399108 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01292869 0,05389895 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01292869 0,05380713 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01292869 0,05371562 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01292869 0,05362442 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01292869 0,05353353 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01292869 0,05344295 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01292869 0,05335267 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01292869 0,0532627 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01292869 0,05317303 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01292869 0,05308367 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01292869 0,0529946 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01292869 0,05290583 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01292869 0,05281736 ! response to UV-C GO:0010225 14 6 0,000 0,01292869 0,05272919 ! astrocyte development GO:0014002 16 6 0,000 0,01292869 0,0526413 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01292869 0,05255371 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01292869 0,05246642 ! interaction with symbiont GO:0051702 14 6 0,000 0,01292869 0,05237941 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01292869 0,05229269 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01292869 0,05220625 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01292869 0,0521201 ! response to copper ion GO:0046688 10 6 0,000 0,01292869 0,05203424 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01292869 0,05194866 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01292869 0,05186335 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01292869 0,05177833 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01292869 0,05169359 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01292869 0,05160912 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01292869 0,05152493 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01292869 0,05144101 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01292869 0,05135737 ! hair follicle maturation GO:0048820 8 6 0,000 0,01292869 0,051274 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01292869 0,0511909 ! Schwann cell development GO:0014044 15 6 0,000 0,01292869 0,05110806 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01292869 0,0510255 ! response to pheromone GO:0019236 6 6 0,000 0,01292869 0,0509432 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01292869 0,05086116 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01292869 0,05077939 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01292869 0,05069789 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01292869 0,05061664 ! subpallium development GO:0021544 15 6 0,000 0,01292869 0,05053565 ! neural tube patterning GO:0021532 8 6 0,000 0,01292869 0,05045492 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01292869 0,05037445 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01292869 0,05029424 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01292869 0,05021428 ! G2 phase GO:0051319 16 6 0,000 0,01292869 0,05013458 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01292869 0,05005512 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01292869 0,04997592 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01292869 0,04989697 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01292869 0,04981827 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01292869 0,04973981 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01292869 0,04966161 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01292869 0,04958365 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01292869 0,04950593 ! receptor internalization GO:0031623 11 6 0,000 0,01292869 0,04942845 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01292869 0,04935122 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01292869 0,04927423 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01292869 0,04919748 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01292869 0,04912097 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01292869 0,04904469 ! protein deubiquitination GO:0016579 16 6 0,000 0,01292869 0,04896866 ! protein destabilization GO:0031648 9 6 0,000 0,01292869 0,04889285 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01292869 0,04881728 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01292869 0,04874195 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01292869 0,04866685 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01292869 0,04859197 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01292869 0,04851733 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01292869 0,04844292 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01292869 0,04836873 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01292869 0,04829477 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01292869 0,04822104 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01292869 0,04814753 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01292869 0,04807425 ! neural plate development GO:0001840 9 6 0,000 0,01292869 0,04800119 ! catecholamine transport GO:0051937 9 6 0,000 0,01292869 0,04792835 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01292869 0,04785573 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01292869 0,04778333 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01292869 0,04771115 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01292869 0,04763919 ! maternal placenta development GO:0001893 12 6 0,000 0,01292869 0,04756744 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01292869 0,04749591 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01292869 0,0474246 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01292869 0,0473535 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01292869 0,04728261 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01292869 0,04721193 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01292869 0,04714147 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01292869 0,04707121 GO:0055081|anion homeostasis, ! response to hypoxia GO:0001666 178 81 1,000 0,01343769 0,04885159 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,01375449 0,04992902 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,01375449 0,04985494 ! protein import into nucleus GO:0006606 174 82 1,000 0,01375449 0,04978108 ! response to drug GO:0042493 149 83 1,000 0,01407453 0,05086404 ! response to oxygen levels GO:0070482 183 83 1,000 0,01407453 0,0507889 ! nuclear import GO:0051170 177 83 1,000 0,01407453 0,05071399 ! T cell activation GO:0042110 189 84 1,000 0,01439779 0,05180237 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,0150539 0,05408335 GO:0002696|positive regulation of leukocyte activation, ! tRNA transcription GO:0009304 17 7 0,000 0,01506737 0,05405225 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01506737 0,053973 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01506737 0,05389397 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01506737 0,05381518 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01506737 0,05373662 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01506737 0,05365828 ! sleep GO:0030431 16 7 0,000 0,01506737 0,05358018 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01506737 0,0535023 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01506737 0,05342465 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01506737 0,05334722 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01506737 0,05327002 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01506737 0,05319304 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01506737 0,05311628 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01506737 0,05303975 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01506737 0,05296343 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01506737 0,05288733 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01506737 0,05281145 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01506737 0,05273579 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01506737 0,05266035 ! glycolipid transport GO:0046836 11 7 0,000 0,01506737 0,05258512 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01506737 0,0525101 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01506737 0,0524353 ! neuron adhesion GO:0007158 14 7 0,000 0,01506737 0,05236072 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01506737 0,05228634 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01506737 0,05221217 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01506737 0,05213822 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01506737 0,05206447 ! mRNA stabilization GO:0048255 18 7 0,000 0,01506737 0,05199094 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01506737 0,05191761 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01506737 0,05184448 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01506737 0,05177157 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01506737 0,05169885 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01506737 0,05162634 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01506737 0,05155404 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01506737 0,05148193 ! lipoprotein transport GO:0042953 14 7 0,000 0,01506737 0,05141003 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01506737 0,05133833 ! rhythmic behavior GO:0007622 17 7 0,000 0,01506737 0,05126683 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01506737 0,05119553 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01506737 0,05112442 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01506737 0,05105351 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01506737 0,0509828 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01506737 0,05091229 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01506737 0,05084197 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01506737 0,05077184 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01506737 0,05070191 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01506737 0,05063216 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01506737 0,05056261 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01506737 0,05049326 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01506737 0,05042409 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01506737 0,05035511 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01506737 0,05028632 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01506737 0,05021771 ! spinal cord patterning GO:0021511 14 7 0,000 0,01506737 0,0501493 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01506737 0,05008107 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01506737 0,05001302 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01506737 0,04994516 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01506737 0,04987748 ! adrenal gland development GO:0030325 17 7 0,000 0,01506737 0,04980999 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01506737 0,04974268 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01506737 0,04967555 ! ovulation GO:0030728 10 7 0,000 0,01506737 0,0496086 ! adenohypophysis development GO:0021984 11 7 0,000 0,01506737 0,04954183 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01506737 0,04947525 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01506737 0,04940884 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01506737 0,04934261 ! microtubule nucleation GO:0007020 21 7 0,000 0,01506737 0,04927655 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01506737 0,04921067 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01506737 0,04914497 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01506737 0,04907944 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01506737 0,04901409 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01506737 0,04894891 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01506737 0,04888391 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01506737 0,04881908 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01506737 0,04875442 ! galactose metabolic process GO:0006012 13 7 0,000 0,01506737 0,04868993 ! vesicle fusion GO:0006906 20 7 0,000 0,01506737 0,04862561 ! response to dietary excess GO:0002021 8 7 0,000 0,01506737 0,04856146 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01506737 0,04849747 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01506737 0,04843366 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01506737 0,04837002 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01506737 0,04830654 ! organ growth GO:0035265 15 7 0,000 0,01506737 0,04824323 ! nucleoside transport GO:0015858 11 7 0,000 0,01506737 0,04818008 ! nucleoside salvage GO:0043174 11 7 0,000 0,01506737 0,0481171 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01506737 0,04805429 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01506737 0,04799163 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01506737 0,04792914 ! parturition GO:0007567 16 7 0,000 0,01506737 0,04786682 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01506737 0,04780465 ! rRNA modification GO:0000154 14 7 0,000 0,01506737 0,04774265 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01506737 0,04768081 ! spindle checkpoint GO:0031577 16 7 0,000 0,01506737 0,04761912 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01506737 0,0475576 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01506737 0,04749624 ! monocyte differentiation GO:0030224 16 7 0,000 0,01506737 0,04743503 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01506737 0,04737398 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01506737 0,04731309 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01506737 0,04725235 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01506737 0,04719177 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01506737 0,04713135 ! fibrinolysis GO:0042730 11 7 0,000 0,01506737 0,04707108 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01506737 0,04701096 ! eating behavior GO:0042755 8 7 0,000 0,01506737 0,046951 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01506737 0,04689119 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01506737 0,04683153 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01506737 0,04677202 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01506737 0,04671267 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01506737 0,04665346 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01506737 0,04659441 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01506737 0,0465355 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01506737 0,04647675 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01506737 0,04641814 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01506737 0,04635968 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01506737 0,04630136 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01506737 0,0462432 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01506737 0,04618517 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01506737 0,0461273 ! histone ubiquitination GO:0016574 9 7 0,000 0,01506737 0,04606957 ! regulation of meiosis GO:0040020 12 7 0,000 0,01506737 0,04601198 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01506737 0,04595454 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01506737 0,04589724 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01506737 0,04584008 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01506737 0,04578306 ! transcription termination GO:0006353 14 7 0,000 0,01506737 0,04572619 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01506737 0,04566946 ! anaphase GO:0051322 18 7 0,000 0,01506737 0,04561287 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01506737 0,04555642 ! axonal fasciculation GO:0007413 19 7 0,000 0,01506737 0,0455001 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01506737 0,04544393 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01506737 0,0453879 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01506737 0,045332 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01506737 0,04527624 ! diuresis GO:0030146 12 7 0,000 0,01506737 0,04522062 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01506737 0,04516513 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01506737 0,04510978 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01506737 0,04505457 ! antibiotic transport GO:0042891 9 7 0,000 0,01506737 0,04499949 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01506737 0,04494455 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01506737 0,04488974 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01506737 0,04483506 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01506737 0,04478052 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01506737 0,0447261 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01506737 0,04467182 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01506737 0,04461768 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01506737 0,04456366 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01506737 0,04450977 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01506737 0,04445602 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01506737 0,04440239 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01506737 0,0443489 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01506737 0,04429553 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01506737 0,04424229 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01506737 0,04418918 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01506737 0,04413619 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01506737 0,04408333 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01506737 0,0440306 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01506737 0,043978 ! muscle adaptation GO:0043500 13 7 0,000 0,01506737 0,04392552 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01506737 0,04387316 ! retina homeostasis GO:0001895 12 7 0,000 0,01506737 0,04382093 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01506737 0,04376883 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01506737 0,04371684 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01506737 0,04366499 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01506737 0,04361325 ! mitochondrion organization GO:0007005 159 87 1,000 0,01538672 0,04448492 ! tube morphogenesis GO:0035239 194 89 1,000 0,01606182 0,04638183 ! protein localization in nucleus GO:0034504 192 89 1,000 0,01606182 0,04632707 ! gland development GO:0048732 220 91 1,000 0,01674943 0,04825338 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,0170979 0,04919924 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01720148 0,04943907 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01720148 0,04938098 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01720148 0,04932302 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01720148 0,04926519 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01720148 0,04920751 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01720148 0,04914995 ! male meiosis GO:0007140 9 8 0,000 0,01720148 0,04909254 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01720148 0,04903525 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01720148 0,0489781 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01720148 0,04892108 ! meiotic prophase I GO:0007128 14 8 0,000 0,01720148 0,0488642 ! response to zinc ion GO:0010043 12 8 0,000 0,01720148 0,04880745 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01720148 0,04875082 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01720148 0,04869433 ! oligopeptide transport GO:0006857 16 8 0,000 0,01720148 0,04863797 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01720148 0,04858175 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01720148 0,04852565 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01720148 0,04846968 ! signal peptide processing GO:0006465 12 8 0,000 0,01720148 0,04841384 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01720148 0,04835812 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01720148 0,04830254 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01720148 0,04824708 ! succinate metabolic process GO:0006105 17 8 0,000 0,01720148 0,04819175 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01720148 0,04813655 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01720148 0,04808148 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01720148 0,04802653 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01720148 0,0479717 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01720148 0,047917 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01720148 0,04786243 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01720148 0,04780798 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01720148 0,04775365 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01720148 0,04769944 ! reflex GO:0060004 17 8 0,000 0,01720148 0,04764536 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01720148 0,0475914 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01720148 0,04753757 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01720148 0,04748385 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01720148 0,04743026 ! pigment granule organization GO:0048753 17 8 0,000 0,01720148 0,04737679 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01720148 0,04732344 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01720148 0,0472702 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01720148 0,04721709 ! histidine catabolic process GO:0006548 10 8 0,000 0,01720148 0,0471641 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01720148 0,04711122 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01720148 0,04705847 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01720148 0,04700583 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01720148 0,04695331 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01720148 0,0469009 ! melanin metabolic process GO:0006582 17 8 0,000 0,01720148 0,04684862 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01720148 0,04679645 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01720148 0,04674439 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01720148 0,04669246 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01720148 0,04664063 ! macrophage activation GO:0042116 13 8 0,000 0,01720148 0,04658892 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01720148 0,04653733 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01720148 0,04648585 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01720148 0,04643449 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01720148 0,04638323 ! purine salvage GO:0043101 12 8 0,000 0,01720148 0,0463321 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01720148 0,04628107 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01720148 0,04623015 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01720148 0,04617935 ! osteoblast development GO:0002076 17 8 0,000 0,01720148 0,04612866 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01720148 0,04607808 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01720148 0,04602761 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01720148 0,04597725 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01720148 0,04592701 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01720148 0,04587687 ! response to UV-B GO:0010224 17 8 0,000 0,01720148 0,04582684 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01720148 0,04577692 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01720148 0,04572711 ! intermediate filament organization GO:0045109 12 8 0,000 0,01720148 0,0456774 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01720148 0,04562781 ! cellular extravasation GO:0045123 13 8 0,000 0,01720148 0,04557832 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01720148 0,04552894 ! response to antibiotic GO:0046677 11 8 0,000 0,01720148 0,04547966 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01720148 0,0454305 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01720148 0,04538144 ! DNA topological change GO:0006265 12 8 0,000 0,01720148 0,04533248 ! response to tropane GO:0014073 15 8 0,000 0,01720148 0,04528363 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01720148 0,04523489 ! melanosome transport GO:0032402 13 8 0,000 0,01720148 0,04518625 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01720148 0,04513771 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01720148 0,04508928 ! mast cell activation GO:0045576 14 8 0,000 0,01720148 0,04504095 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01720148 0,04499273 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01720148 0,04494461 ! gas homeostasis GO:0033483 14 8 0,000 0,01720148 0,04489659 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01720148 0,04484868 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01720148 0,04480086 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01720148 0,04475315 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01720148 0,04470554 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01720148 0,04465803 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01720148 0,04461063 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01720148 0,04456332 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01720148 0,04451611 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01720148 0,04446901 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01720148 0,044422 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01720148 0,04437509 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01720148 0,04432828 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01720148 0,04428157 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01720148 0,04423496 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01720148 0,04418844 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01720148 0,04414203 ! hormone catabolic process GO:0042447 17 8 0,000 0,01720148 0,04409571 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01720148 0,04404949 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01720148 0,04400336 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01720148 0,04395733 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01720148 0,0439114 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01720148 0,04386556 ! adult feeding behavior GO:0008343 10 8 0,000 0,01720148 0,04381982 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01720148 0,04377418 ! ATP catabolic process GO:0006200 11 8 0,000 0,01720148 0,04372863 ! blastocyst growth GO:0001832 19 8 0,000 0,01720148 0,04368317 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01720148 0,04363781 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01720148 0,04359254 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01720148 0,04354737 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01720148 0,04350229 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01720148 0,0434573 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01720148 0,04341241 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01720148 0,04336761 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01720148 0,0433229 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01720148 0,04327828 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01720148 0,04323376 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01720148 0,04318932 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01720148 0,04314498 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01720148 0,04310073 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01720148 0,04305657 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01720148 0,0430125 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01720148 0,04296852 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01720148 0,04292463 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01720148 0,04288083 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01720148 0,04283712 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01720148 0,04279349 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,01780406 0,04424752 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01816173 0,04509054 ! leukocyte differentiation GO:0002521 232 98 1,000 0,01925292 0,04775115 ! axon extension GO:0048675 16 9 0,000 0,01933102 0,04789623 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01933102 0,04784771 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01933102 0,04779928 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01933102 0,04775095 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01933102 0,04770271 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01933102 0,04765458 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01933102 0,04760654 ! reproductive behavior GO:0019098 22 9 0,000 0,01933102 0,0475586 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01933102 0,04751075 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01933102 0,047463 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01933102 0,04741535 ! UTP metabolic process GO:0046051 10 9 0,000 0,01933102 0,04736779 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01933102 0,04732033 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01933102 0,04727296 ! artery development GO:0060840 25 9 0,000 0,01933102 0,04722569 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01933102 0,04717851 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01933102 0,04713142 ! equilibrioception GO:0050957 20 9 0,000 0,01933102 0,04708443 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01933102 0,04703754 ! chemosensory behavior GO:0007635 21 9 0,000 0,01933102 0,04699073 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01933102 0,04694402 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01933102 0,04689741 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01933102 0,04685088 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01933102 0,04680445 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01933102 0,04675811 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01933102 0,04671186 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01933102 0,0466657 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01933102 0,04661963 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01933102 0,04657366 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01933102 0,04652777 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01933102 0,04648198 ! protein targeting to ER GO:0045047 25 9 0,000 0,01933102 0,04643627 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01933102 0,04639066 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01933102 0,04634513 ! T cell selection GO:0045058 27 9 0,000 0,01933102 0,04629969 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01933102 0,04625435 ! glycine catabolic process GO:0006546 15 9 0,000 0,01933102 0,04620909 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01933102 0,04616392 ! endosome organization GO:0007032 20 9 0,000 0,01933102 0,04611884 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01933102 0,04607384 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01933102 0,04602893 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01933102 0,04598412 ! mannose metabolic process GO:0006013 13 9 0,000 0,01933102 0,04593938 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01933102 0,04589474 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01933102 0,04585018 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01933102 0,04580571 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01933102 0,04576132 ! receptor clustering GO:0043113 20 9 0,000 0,01933102 0,04571703 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01933102 0,04567281 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01933102 0,04562868 ! retinol metabolic process GO:0042572 20 9 0,000 0,01933102 0,04558464 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01933102 0,04554068 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01933102 0,04549681 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01933102 0,04545302 ! macrophage differentiation GO:0030225 15 9 0,000 0,01933102 0,04540931 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01933102 0,04536569 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01933102 0,04532216 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01933102 0,0452787 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01933102 0,04523533 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01933102 0,04519205 ! response to amine stimulus GO:0014075 13 9 0,000 0,01933102 0,04514884 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01933102 0,04510572 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01933102 0,04506268 ! erythrocyte development GO:0048821 17 9 0,000 0,01933102 0,04501972 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01933102 0,04497684 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01933102 0,04493405 ! renal water homeostasis GO:0003091 15 9 0,000 0,01933102 0,04489134 ! postreplication repair GO:0006301 25 9 0,000 0,01933102 0,04484871 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01933102 0,04480615 ! icosanoid secretion GO:0032309 15 9 0,000 0,01933102 0,04476368 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01933102 0,04472129 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01933102 0,04467898 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01933102 0,04463676 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01933102 0,04459461 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01933102 0,04455253 ! sterol catabolic process GO:0016127 14 9 0,000 0,01933102 0,04451054 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01933102 0,04446863 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01933102 0,0444268 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01933102 0,04438504 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01933102 0,04434337 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01933102 0,04430177 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01933102 0,04426025 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01933102 0,04421881 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01933102 0,04417744 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01933102 0,04413616 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01933102 0,04409495 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01933102 0,04405381 ! purine base metabolic process GO:0006144 25 9 0,000 0,01933102 0,04401276 ! pigment granule transport GO:0051904 17 9 0,000 0,01933102 0,04397178 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01933102 0,04393087 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01933102 0,04389004 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01933102 0,04384929 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01933102 0,04380862 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01933102 0,04376801 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01933102 0,04372749 ! mitochondrion localization GO:0051646 18 9 0,000 0,01933102 0,04368704 ! hormone metabolic process GO:0042445 171 100 1,000 0,01999539 0,0451467 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02145601 0,04839985 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02145601 0,0483552 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02145601 0,04831063 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02145601 0,04826615 ! associative learning GO:0008306 21 10 0,000 0,02145601 0,04822175 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02145601 0,04817742 ! phosphate transport GO:0006817 24 10 0,000 0,02145601 0,04813318 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02145601 0,04808902 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02145601 0,04804495 ! CTP metabolic process GO:0046036 11 10 0,000 0,02145601 0,04800095 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02145601 0,04795703 ! GTP metabolic process GO:0046039 11 10 0,000 0,02145601 0,0479132 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02145601 0,04786944 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02145601 0,04782576 ! social behavior GO:0035176 29 10 0,000 0,02145601 0,04778217 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02145601 0,04773865 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02145601 0,04769521 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02145601 0,04765185 ! androgen metabolic process GO:0008209 17 10 0,000 0,02145601 0,04760857 ! phospholipid efflux GO:0033700 19 10 0,000 0,02145601 0,04756537 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02145601 0,04752225 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02145601 0,0474792 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02145601 0,04743623 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02145601 0,04739334 ! lung alveolus development GO:0048286 26 10 0,000 0,02145601 0,04735053 ! pathogenesis GO:0009405 17 10 0,000 0,02145601 0,0473078 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02145601 0,04726514 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02145601 0,04722256 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02145601 0,04718005 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02145601 0,04713762 ! endoderm development GO:0007492 18 10 0,000 0,02145601 0,04709527 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02145601 0,047053 ! arginine catabolic process GO:0006527 17 10 0,000 0,02145601 0,0470108 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02145601 0,04696867 ! proline metabolic process GO:0006560 13 10 0,000 0,02145601 0,04692662 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02145601 0,04688465 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02145601 0,04684275 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02145601 0,04680093 ! V(D)J recombination GO:0033151 34 10 0,000 0,02145601 0,04675918 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02145601 0,0467175 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02145601 0,0466759 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02145601 0,04663437 ! B cell proliferation GO:0042100 19 10 0,000 0,02145601 0,04659292 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02145601 0,04655154 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02145601 0,04651024 ! multicellular organism growth GO:0035264 19 10 0,000 0,02145601 0,046469 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02145601 0,04642785 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02145601 0,04638676 ! ruffle organization GO:0031529 17 10 0,000 0,02145601 0,04634574 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02145601 0,0463048 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02145601 0,04626393 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02145601 0,04622314 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02145601 0,04618241 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02145601 0,04614176 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02145601 0,04610118 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,02145601 0,04606067 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02145601 0,04602023 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02145601 0,04597986 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02145601 0,04593956 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02145601 0,04589933 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02145601 0,04585918 ! segment specification GO:0007379 15 10 0,000 0,02145601 0,04581909 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02145601 0,04577907 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02145601 0,04573912 ! response to dsRNA GO:0043331 23 10 0,000 0,02145601 0,04569925 ! DNA ligation GO:0006266 18 10 0,000 0,02145601 0,04565944 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02145601 0,0456197 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02145601 0,04558003 ! melanosome localization GO:0032400 16 10 0,000 0,02145601 0,04554043 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02145601 0,0455009 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02145601 0,04546144 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02145601 0,04542204 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02145601 0,04538272 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02145601 0,04534346 ! induction of an organ GO:0001759 17 10 0,000 0,02145601 0,04530427 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02145601 0,04526514 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02145601 0,04522609 ! protein sumoylation GO:0016925 17 10 0,000 0,02145601 0,0451871 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02145601 0,04514818 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02145601 0,04510933 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02145601 0,04507054 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02145601 0,04503182 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02145601 0,04499316 ! salivary gland development GO:0007431 28 10 0,000 0,02145601 0,04495458 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02145601 0,04491606 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02145601 0,0448776 ! midbrain development GO:0030901 14 10 0,000 0,02145601 0,04483921 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02145601 0,04480089 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02145601 0,04476263 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02145601 0,04472443 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02145601 0,04468631 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02145601 0,04464824 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02145601 0,04461024 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02145601 0,04457231 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02145601 0,04453444 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02145601 0,04449664 ! detection of calcium ion GO:0005513 24 10 0,000 0,02145601 0,04445889 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02145601 0,04442122 ! blastocyst formation GO:0001825 18 10 0,000 0,02145601 0,0443836 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02145601 0,04434606 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02145601 0,04430857 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02145601 0,04427115 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02145601 0,04423379 ! response to nicotine GO:0035094 20 10 0,000 0,02145601 0,04419649 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02145601 0,04415926 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02145601 0,04412209 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02357646 0,04844179 ! respiratory burst GO:0045730 17 11 0,000 0,02357646 0,04840108 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02357646 0,04836044 ! neuron fate specification GO:0048665 18 11 0,000 0,02357646 0,04831987 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02357646 0,04827937 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02357646 0,04823893 ! thyroid gland development GO:0030878 26 11 0,000 0,02357646 0,04819856 ! synapsis GO:0007129 14 11 0,000 0,02357646 0,04815826 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02357646 0,04811803 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02357646 0,04807787 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02357646 0,04803777 ! response to pain GO:0048265 27 11 0,000 0,02357646 0,04799774 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02357646 0,04795777 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02357646 0,04791787 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02357646 0,04787804 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02357646 0,04783828 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02357646 0,04779858 ! bone resorption GO:0045453 16 11 0,000 0,02357646 0,04775894 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02357646 0,04771937 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,02357646 0,04767987 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02357646 0,04764043 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02357646 0,04760106 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02357646 0,04756175 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02357646 0,04752251 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02357646 0,04748333 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02357646 0,04744422 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02357646 0,04740517 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02357646 0,04736619 ! UV protection GO:0009650 20 11 0,000 0,02357646 0,04732727 ! adult heart development GO:0007512 16 11 0,000 0,02357646 0,04728841 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02357646 0,04724962 ! macroautophagy GO:0016236 19 11 0,000 0,02357646 0,04721089 ! temperature homeostasis GO:0001659 18 11 0,000 0,02357646 0,04717222 ! behavioral fear response GO:0001662 27 11 0,000 0,02357646 0,04713362 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02357646 0,04709508 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02357646 0,0470566 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02357646 0,04701819 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02357646 0,04697984 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02357646 0,04694155 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02357646 0,04690333 ! regulation of organ growth GO:0046620 14 11 0,000 0,02357646 0,04686516 ! pigment granule localization GO:0051875 20 11 0,000 0,02357646 0,04682706 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02357646 0,04678902 ! vasoconstriction GO:0042310 20 11 0,000 0,02357646 0,04675104 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02357646 0,04671313 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02357646 0,04667527 ! embryonic axis specification GO:0000578 19 11 0,000 0,02357646 0,04663748 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02357646 0,04659974 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02357646 0,04656207 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02357646 0,04652446 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02357646 0,04648691 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02357646 0,04644942 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02357646 0,04641199 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02357646 0,04637462 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02357646 0,04633732 ! prophase GO:0051324 17 11 0,000 0,02357646 0,04630007 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02357646 0,04626288 ! nucleosome positioning GO:0016584 15 11 0,000 0,02357646 0,04622575 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02357646 0,04618868 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02357646 0,04615167 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02357646 0,04611472 ! apical protein localization GO:0045176 18 11 0,000 0,02357646 0,04607783 ! acid secretion GO:0046717 20 11 0,000 0,02357646 0,04604099 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02357646 0,04600422 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02357646 0,04596751 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02357646 0,04593085 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02357646 0,04589425 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02357646 0,04585771 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02357646 0,04582123 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02357646 0,0457848 ! cholesterol efflux GO:0033344 21 11 0,000 0,02357646 0,04574844 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02357646 0,04571213 ! oocyte development GO:0048599 20 11 0,000 0,02357646 0,04567588 ! germ cell migration GO:0008354 26 11 0,000 0,02357646 0,04563969 ! embryonic gut development GO:0048566 19 11 0,000 0,02357646 0,04560355 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02357646 0,04556747 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02357646 0,04553145 ! activation of innate immune response GO:0002218 16 11 0,000 0,02357646 0,04549548 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02357646 0,04545958 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02357646 0,04542373 ! lysogeny GO:0030069 22 11 0,000 0,02357646 0,04538793 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02357646 0,04535219 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02357646 0,04531651 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02357646 0,04528088 ! nucleus localization GO:0051647 22 11 0,000 0,02357646 0,04524531 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02569237 0,04926723 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02569237 0,04922859 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02569237 0,04919001 ! mating GO:0007618 17 12 0,000 0,02569237 0,04915149 ! protein complex disassembly GO:0043241 28 12 0,000 0,02569237 0,04911303 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02569237 0,04907463 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02569237 0,04903629 ! hippocampus development GO:0021766 29 12 0,000 0,02569237 0,04899801 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02569237 0,04895979 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02569237 0,04892163 ! T cell proliferation GO:0042098 32 12 0,000 0,02569237 0,04888353 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02569237 0,04884549 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02569237 0,0488075 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02569237 0,04876958 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02569237 0,04873172 ! drug transport GO:0015893 16 12 0,000 0,02569237 0,04869391 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02569237 0,04865616 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02569237 0,04861847 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02569237 0,04858084 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02569237 0,04854327 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02569237 0,04850576 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02569237 0,0484683 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02569237 0,0484309 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02569237 0,04839356 ! lipid digestion GO:0044241 21 12 0,000 0,02569237 0,04835628 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02569237 0,04831905 ! entry into host cell GO:0030260 34 12 0,000 0,02569237 0,04828189 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02569237 0,04824477 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02569237 0,04820772 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02569237 0,04817072 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02569237 0,04813378 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02569237 0,0480969 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02569237 0,04806007 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02569237 0,0480233 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02569237 0,04798658 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02569237 0,04794992 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02569237 0,04791332 ! cranial nerve development GO:0021545 23 12 0,000 0,02569237 0,04787677 ! fucose catabolic process GO:0019317 25 12 0,000 0,02569237 0,04784028 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02569237 0,04780385 ! histone acetylation GO:0016573 27 12 0,000 0,02569237 0,04776747 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02569237 0,04773114 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02569237 0,04769487 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02569237 0,04765866 ! zymogen activation GO:0031638 18 12 0,000 0,02569237 0,0476225 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02569237 0,04758639 ! T cell homeostasis GO:0043029 28 12 0,000 0,02569237 0,04755034 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02569237 0,04751435 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02569237 0,0474784 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02569237 0,04744252 ! oocyte differentiation GO:0009994 21 12 0,000 0,02569237 0,04740668 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02569237 0,04737091 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02569237 0,04733518 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02569237 0,04729951 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02569237 0,04726389 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02569237 0,04722833 ! defense response to fungus GO:0050832 15 12 0,000 0,02569237 0,04719282 ! developmental induction GO:0031128 22 12 0,000 0,02569237 0,04715736 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02569237 0,04712196 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02569237 0,04708661 ! response to cold GO:0009409 17 12 0,000 0,02569237 0,04705131 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02569237 0,04701607 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02569237 0,04698088 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02780375 0,05080371 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02780375 0,05076574 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02780375 0,05072783 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02780375 0,05068997 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02780375 0,05065217 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02780375 0,05061443 ! peroxisomal transport GO:0043574 28 13 0,000 0,02780375 0,05057674 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02780375 0,05053911 ! cartilage condensation GO:0001502 22 13 0,000 0,02780375 0,05050153 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02780375 0,05046401 ! organelle fusion GO:0048284 36 13 0,000 0,02780375 0,05042655 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02780375 0,05038914 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02780375 0,05035179 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02780375 0,05031449 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02780375 0,05027725 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02780375 0,05024006 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02780375 0,05020293 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02780375 0,05016585 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02780375 0,05012883 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02780375 0,05009186 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02780375 0,05005495 ! methionine metabolic process GO:0006555 31 13 0,000 0,02780375 0,05001809 ! plasma membrane organization GO:0007009 27 13 0,000 0,02780375 0,04998128 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02780375 0,04994453 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02780375 0,04990783 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02780375 0,04987119 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02780375 0,0498346 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,02780375 0,04979807 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02780375 0,04976158 ! exocrine system development GO:0035272 34 13 0,000 0,02780375 0,04972515 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02780375 0,04968878 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02780375 0,04965246 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02780375 0,04961619 ! L-glutamate transport GO:0015813 30 13 0,000 0,02780375 0,04957997 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02780375 0,04954381 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02780375 0,0495077 ! protein homotetramerization GO:0051289 24 13 0,000 0,02780375 0,04947164 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02780375 0,04943563 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02780375 0,04939968 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02780375 0,04936378 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02780375 0,04932793 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02780375 0,04929213 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02780375 0,04925639 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02780375 0,0492207 ! histone methylation GO:0016571 29 13 0,000 0,02780375 0,04918506 ! chromatin silencing GO:0006342 29 13 0,000 0,02780375 0,04914947 ! gland morphogenesis GO:0022612 31 13 0,000 0,02780375 0,04911393 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02780375 0,04907844 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02780375 0,049043 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02780375 0,04900762 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02780375 0,04897229 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02780375 0,048937 ! spleen development GO:0048536 24 13 0,000 0,02780375 0,04890177 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02780375 0,04886659 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02780375 0,04883146 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02780375 0,04879638 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02780375 0,04876135 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02780375 0,04872637 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02780375 0,04869144 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02780375 0,04865656 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02780375 0,04862173 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02780375 0,04858695 ! insulin secretion GO:0030073 24 13 0,000 0,02780375 0,04855222 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02780375 0,04851754 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02780375 0,04848291 ! acrosome reaction GO:0007340 19 13 0,000 0,02780375 0,04844833 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02780375 0,0484138 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02780375 0,04837932 ! rRNA transcription GO:0009303 28 14 0,000 0,02991062 0,05200828 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02991062 0,05197129 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02991062 0,05193436 ! water transport GO:0006833 21 14 0,000 0,02991062 0,05189747 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02991062 0,05186064 ! non-recombinational repair GO:0000726 29 14 0,000 0,02991062 0,05182386 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02991062 0,05178713 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02991062 0,05175045 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02991062 0,05171383 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02991062 0,05167726 ! lipid localization GO:0010876 32 14 0,000 0,02991062 0,05164073 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,02991062 0,05160426 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02991062 0,05156785 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02991062 0,05153148 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02991062 0,05149516 ! arginine metabolic process GO:0006525 21 14 0,000 0,02991062 0,0514589 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02991062 0,05142269 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02991062 0,05138653 ! regulation of heart rate GO:0002027 25 14 0,000 0,02991062 0,05135041 ! fear response GO:0042596 34 14 0,000 0,02991062 0,05131435 ! organic alcohol transport GO:0015850 29 14 0,000 0,02991062 0,05127834 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02991062 0,05124238 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02991062 0,05120647 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02991062 0,05117062 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02991062 0,05113481 ! bone mineralization GO:0030282 18 14 0,000 0,02991062 0,05109905 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02991062 0,05106334 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02991062 0,05102768 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02991062 0,05099207 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02991062 0,05095651 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02991062 0,050921 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02991062 0,05088554 ! ribosome assembly GO:0042255 18 14 0,000 0,02991062 0,05085013 ! cerebellum development GO:0021549 23 14 0,000 0,02991062 0,05081477 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02991062 0,05077946 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02991062 0,05074419 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02991062 0,05070898 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02991062 0,05067381 ! NADP metabolic process GO:0006739 24 14 0,000 0,02991062 0,0506387 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02991062 0,05060363 ! oxygen transport GO:0015671 22 14 0,000 0,02991062 0,05056861 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02991062 0,05053364 ! male genitalia development GO:0030539 26 14 0,000 0,02991062 0,05049871 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02991062 0,05046384 ! regulation of axon extension GO:0030516 43 14 0,000 0,02991062 0,05042901 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,02991062 0,05039423 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03201298 0,05389918 ! lactation GO:0007595 30 15 0,000 0,03201298 0,05386206 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,03201298 0,05382499 ! reproductive cellular process GO:0048610 22 15 0,000 0,03201298 0,05378797 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03201298 0,053751 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03201298 0,05371408 ! superoxide anion generation GO:0042554 22 15 0,000 0,03201298 0,05367722 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03201298 0,0536404 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03201298 0,05360364 ! copper ion transport GO:0006825 22 15 0,000 0,03201298 0,05356692 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03201298 0,05353026 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03201298 0,05349364 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03201298 0,05345708 ! sulfate transport GO:0008272 27 15 0,000 0,03201298 0,05342056 ! response to cAMP GO:0051591 25 15 0,000 0,03201298 0,0533841 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03201298 0,05334769 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03201298 0,05331132 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03201298 0,053275 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03201298 0,05323874 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03201298 0,05320252 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03201298 0,05316635 ! vesicle coating GO:0006901 38 15 0,000 0,03201298 0,05313024 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03201298 0,05309417 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03201298 0,05305815 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03201298 0,05302217 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03201298 0,05298625 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03201298 0,05295038 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03201298 0,05291455 ! regulation of vasodilation GO:0042312 27 15 0,000 0,03201298 0,05287877 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03201298 0,05284304 ! histone deacetylation GO:0016575 24 15 0,000 0,03201298 0,05280736 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03201298 0,05277173 ! water homeostasis GO:0030104 28 15 0,000 0,03201298 0,05273615 ! cofactor transport GO:0051181 30 15 0,000 0,03201298 0,05270061 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03201298 0,05266512 ! muscle maintenance GO:0046716 26 15 0,000 0,03201298 0,05262968 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03201298 0,05259429 ! intestinal absorption GO:0050892 31 15 0,000 0,03201298 0,05255894 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03201298 0,05252364 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03201298 0,05248839 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03201298 0,05245319 ! cell killing GO:0001906 32 15 0,000 0,03201298 0,05241803 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03201298 0,05238292 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,03201298 0,05234786 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03201298 0,05231285 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03201298 0,05227788 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03201298 0,05224296 ! actin filament polymerization GO:0030041 27 15 0,000 0,03201298 0,05220808 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03201298 0,05217325 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03411084 0,05555519 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03411084 0,05551818 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03411084 0,05548122 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03411084 0,0554443 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03411084 0,05540744 ! bone remodeling GO:0046849 28 16 0,000 0,03411084 0,05537062 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03411084 0,05533386 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03411084 0,05529714 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03411084 0,05526047 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03411084 0,05522385 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03411084 0,05518728 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03411084 0,05515075 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03411084 0,05511428 ! startle response GO:0001964 28 16 0,000 0,03411084 0,05507785 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03411084 0,05504147 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03411084 0,05500514 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03411084 0,05496886 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03411084 0,05493262 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03411084 0,05489643 ! pituitary gland development GO:0021983 30 16 0,000 0,03411084 0,05486029 ! response to osmotic stress GO:0006970 27 16 0,000 0,03411084 0,0548242 ! lysosomal transport GO:0007041 31 16 0,000 0,03411084 0,05478816 ! L-amino acid transport GO:0015807 33 16 0,000 0,03411084 0,05475216 ! stem cell development GO:0048864 46 16 0,000 0,03411084 0,05471621 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03411084 0,05468031 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03411084 0,05464445 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03411084 0,05460864 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03411084 0,05457288 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03411084 0,05453716 ! axon cargo transport GO:0008088 46 16 0,000 0,03411084 0,0545015 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03411084 0,05446587 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03411084 0,0544303 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03411084 0,05439477 ! DNA replication initiation GO:0006270 28 16 0,000 0,03411084 0,05435929 ! neuron recognition GO:0008038 40 16 0,000 0,03411084 0,05432385 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03411084 0,05428846 ! tissue regeneration GO:0042246 27 16 0,000 0,03411084 0,05425312 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03411084 0,05421782 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03411084 0,05418257 ! biomineral formation GO:0031214 22 16 0,000 0,03411084 0,05414736 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03411084 0,0541122 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03411084 0,05407708 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03411084 0,05404202 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03411084 0,05400699 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03411084 0,05397201 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03411084 0,05393708 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03411084 0,05390219 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,03411084 0,05386735 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03620422 0,05713624 ! metencephalon development GO:0022037 32 17 0,000 0,03620422 0,05709936 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03620422 0,05706252 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03620422 0,05702573 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03620422 0,05698899 ! signal complex assembly GO:0007172 47 17 0,000 0,03620422 0,05695229 ! filopodium assembly GO:0046847 42 17 0,000 0,03620422 0,05691564 ! endothelial cell migration GO:0043542 31 17 0,000 0,03620422 0,05687904 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03620422 0,05684248 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03620422 0,05680598 ! glial cell development GO:0021782 28 17 0,000 0,03620422 0,05676952 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03620422 0,0567331 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03620422 0,05669673 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03620422 0,05666041 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03620422 0,05662414 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03620422 0,05658791 ! myoblast differentiation GO:0045445 50 17 0,000 0,03620422 0,05655173 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03620422 0,05651559 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03620422 0,05647951 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03620422 0,05644346 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03620422 0,05640747 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03620422 0,05637151 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03620422 0,05633561 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03620422 0,05629975 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03620422 0,05626393 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03620422 0,05622817 ! membrane budding GO:0006900 42 17 0,000 0,03620422 0,05619244 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03620422 0,05615677 ! regulation of protein binding GO:0043393 33 17 0,000 0,03620422 0,05612113 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03620422 0,05608555 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03620422 0,05605 ! genitalia development GO:0048806 32 17 0,000 0,03620422 0,05601451 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03620422 0,05597905 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03620422 0,05594365 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03620422 0,05590828 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03620422 0,05587297 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03620422 0,05583769 ! steroid catabolic process GO:0006706 34 17 0,000 0,03620422 0,05580246 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03620422 0,05576728 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03620422 0,05573214 ! gas transport GO:0015669 26 17 0,000 0,03620422 0,05569704 ! organic cation transport GO:0015695 32 17 0,000 0,03620422 0,05566199 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03620422 0,05562698 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03620422 0,05559202 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03620422 0,0555571 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,03829312 0,05872573 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03829312 0,05868889 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03829312 0,05865209 ! limbic system development GO:0021761 40 18 0,000 0,03829312 0,05861534 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03829312 0,05857864 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03829312 0,05854198 ! adult walking behavior GO:0007628 36 18 0,000 0,03829312 0,05850537 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03829312 0,0584688 ! heart looping GO:0001947 34 18 0,000 0,03829312 0,05843228 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03829312 0,05839581 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03829312 0,05835938 ! centrosome cycle GO:0007098 26 18 0,000 0,03829312 0,05832299 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03829312 0,05828666 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03829312 0,05825036 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03829312 0,05821411 ! glycine metabolic process GO:0006544 30 18 0,000 0,03829312 0,05817791 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03829312 0,05814175 ! response to retinoic acid GO:0032526 31 18 0,000 0,03829312 0,05810564 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03829312 0,05806957 ! DNA integration GO:0015074 32 18 0,000 0,03829312 0,05803355 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03829312 0,05799757 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03829312 0,05796164 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03829312 0,05792575 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03829312 0,0578899 ! neural crest cell migration GO:0001755 41 18 0,000 0,03829312 0,0578541 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03829312 0,05781835 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03829312 0,05778263 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03829312 0,05774696 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03829312 0,05771134 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03829312 0,05767576 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03829312 0,05764022 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03829312 0,05760473 ! detection of bacterium GO:0016045 22 18 0,000 0,03829312 0,05756928 ! nerve development GO:0021675 34 18 0,000 0,03829312 0,05753388 ! defense response to virus GO:0051607 43 18 0,000 0,03829312 0,05749851 ! microspike assembly GO:0030035 46 18 0,000 0,03829312 0,0574632 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03829312 0,05742792 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03829312 0,05739269 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04037755 0,06047967 ! positive regulation of translation GO:0045727 31 19 0,000 0,04037755 0,06044261 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04037755 0,0604056 ! neuron maturation GO:0042551 46 19 0,000 0,04037755 0,06036863 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04037755 0,06033171 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04037755 0,06029483 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04037755 0,060258 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04037755 0,06022121 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04037755 0,06018447 ! inositol metabolic process GO:0006020 33 19 0,000 0,04037755 0,06014777 ! memory GO:0007613 34 19 0,000 0,04037755 0,06011112 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04037755 0,06007451 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04037755 0,06003794 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04037755 0,06000143 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04037755 0,05996495 ! cerebral cortex development GO:0021987 40 19 0,000 0,04037755 0,05992852 ! pigmentation during development GO:0048066 42 19 0,000 0,04037755 0,05989213 ! response to vitamin A GO:0033189 32 19 0,000 0,04037755 0,05985579 ! heme metabolic process GO:0042168 40 19 0,000 0,04037755 0,05981949 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04037755 0,05978324 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04037755 0,05974703 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,04037755 0,05971086 ! response to fungus GO:0009620 26 19 0,000 0,04037755 0,05967474 ! peptide cross-linking GO:0018149 39 19 0,000 0,04037755 0,05963866 ! protein export from nucleus GO:0006611 40 19 0,000 0,04037755 0,05960262 ! heart process GO:0003015 32 19 0,000 0,04037755 0,05956663 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04037755 0,05953068 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04037755 0,05949478 ! visual learning GO:0008542 38 19 0,000 0,04037755 0,05945892 ! cellular pigmentation GO:0033059 37 19 0,000 0,04037755 0,0594231 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04037755 0,05938732 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04037755 0,05935159 ! vitamin transport GO:0051180 31 19 0,000 0,04037755 0,0593159 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04037755 0,05928025 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04037755 0,05924465 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04037755 0,05920909 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04037755 0,05917357 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04037755 0,0591381 ! cilium assembly GO:0042384 38 19 0,000 0,04037755 0,05910266 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04037755 0,05906727 ! protein secretion GO:0009306 45 20 0,000 0,04245752 0,06207284 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04245752 0,06203571 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04245752 0,06199863 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04245752 0,06196159 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04245752 0,0619246 ! skin development GO:0043588 42 20 0,000 0,04245752 0,06188765 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04245752 0,06185075 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04245752 0,06181389 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,04245752 0,06177708 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,04245752 0,0617403 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04245752 0,06170357 ! response to vitamin GO:0033273 36 20 0,000 0,04245752 0,06166689 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04245752 0,06163025 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04245752 0,06159365 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04245752 0,0615571 ! response to alkaloid GO:0043279 38 20 0,000 0,04245752 0,06152059 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04245752 0,06148412 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04245752 0,0614477 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04245752 0,06141131 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04245752 0,06137498 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04245752 0,06133868 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04245752 0,06130243 ! body fluid secretion GO:0007589 33 20 0,000 0,04245752 0,06126622 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04245752 0,06123005 ! peptide secretion GO:0002790 38 20 0,000 0,04245752 0,06119393 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04245752 0,06115785 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,04245752 0,06112181 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04245752 0,06108581 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04245752 0,06104986 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04245752 0,06101395 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04245752 0,06097808 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04245752 0,06094225 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04245752 0,06090646 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04245752 0,06087072 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04245752 0,06083502 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04245752 0,06079936 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04245752 0,06076374 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04245752 0,06072817 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04245752 0,06069263 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04245752 0,06065714 ! regulation of cell killing GO:0031341 46 21 0,000 0,04453304 0,06358516 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04453304 0,06354802 ! hormone secretion GO:0046879 39 21 0,000 0,04453304 0,06351092 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04453304 0,06347387 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04453304 0,06343685 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04453304 0,06339989 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04453304 0,06336296 ! ovarian follicle development GO:0001541 39 21 0,000 0,04453304 0,06332608 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04453304 0,06328924 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04453304 0,06325244 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04453304 0,06321569 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04453304 0,06317898 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04453304 0,06314231 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04453304 0,06310569 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04453304 0,0630691 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,04453304 0,06303256 ! sensory perception of pain GO:0019233 33 21 0,000 0,04453304 0,06299607 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04453304 0,06295961 ! diencephalon development GO:0021536 36 21 0,000 0,04453304 0,0629232 ! collagen fibril organization GO:0030199 62 21 0,000 0,04453304 0,06288682 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04453304 0,06285049 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04453304 0,06281421 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04453304 0,06277796 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04453304 0,06274176 ! collagen catabolic process GO:0030574 29 21 0,000 0,04453304 0,06270559 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04453304 0,06266947 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04453304 0,06263339 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04453304 0,06259736 ! actin filament-based movement GO:0030048 47 21 0,000 0,04453304 0,06256136 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04660411 0,06543325 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04660411 0,06539566 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04660411 0,06535812 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04660411 0,06532063 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04660411 0,06528317 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04660411 0,06524576 ! microtubule-based transport GO:0010970 59 22 0,000 0,04660411 0,06520839 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04660411 0,06517107 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04660411 0,06513378 ! vacuolar transport GO:0007034 41 22 0,000 0,04660411 0,06509654 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04660411 0,06505934 ! fucose metabolic process GO:0006004 44 22 0,000 0,04660411 0,06502219 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04660411 0,06498508 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04660411 0,064948 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04660411 0,06491098 ! ureteric bud development GO:0001657 50 22 0,000 0,04660411 0,06487399 ! stem cell differentiation GO:0048863 57 22 0,000 0,04660411 0,06483705 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04660411 0,06480014 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04660411 0,06476328 ! cytolysis GO:0019835 27 22 0,000 0,04660411 0,06472647 ! renal system process GO:0003014 42 22 0,000 0,04660411 0,06468969 ! vasodilation GO:0042311 40 22 0,000 0,04660411 0,06465295 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04660411 0,06461626 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04660411 0,06457961 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04660411 0,064543 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,04660411 0,06450643 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04660411 0,0644699 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04660411 0,06443342 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04660411 0,06439698 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04660411 0,06436057 ! sarcomere organization GO:0045214 32 22 0,000 0,04660411 0,06432421 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04660411 0,06428789 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04660411 0,06425161 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04660411 0,06421537 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04660411 0,06417917 ! gut development GO:0048565 44 22 0,000 0,04660411 0,06414302 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04660411 0,0641069 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04660411 0,06407082 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04660411 0,06403479 ! protein stabilization GO:0050821 41 22 0,000 0,04660411 0,06399879 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04867076 0,06679926 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04867076 0,06676175 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04867076 0,06672428 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04867076 0,06668686 ! viral genome replication GO:0019079 44 23 0,000 0,04867076 0,06664948 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04867076 0,06661214 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04867076 0,06657485 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04867076 0,06653759 ! regeneration GO:0031099 42 23 0,000 0,04867076 0,06650038 ! axis specification GO:0009798 43 23 0,000 0,04867076 0,06646321 ! visual behavior GO:0007632 46 23 0,000 0,04867076 0,06642607 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04867076 0,06638899 ! response to ethanol GO:0045471 47 23 0,000 0,04867076 0,06635194 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04867076 0,06631493 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04867076 0,06627797 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04867076 0,06624104 ! peroxisome organization GO:0007031 43 23 0,000 0,04867076 0,06620416 ! lysosome organization GO:0007040 47 23 0,000 0,04867076 0,06616732 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04867076 0,06613052 ! vesicle targeting GO:0006903 49 23 0,000 0,04867076 0,06609376 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04867076 0,06605704 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04867076 0,06602036 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04867076 0,06598373 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04867076 0,06594713 ! DNA modification GO:0006304 36 23 0,000 0,04867076 0,06591057 ! fatty acid transport GO:0015908 47 23 0,000 0,04867076 0,06587406 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04867076 0,06583758 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04867076 0,06580115 ! hormone transport GO:0009914 41 23 0,000 0,04867076 0,06576475 ! cell-cell recognition GO:0009988 28 23 0,000 0,04867076 0,0657284 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04867076 0,06569209 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04867076 0,06565581 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04867076 0,06561958 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05073299 0,06836221 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05073299 0,06832453 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05073299 0,06828688 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05073299 0,06824928 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05073299 0,06821172 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05073299 0,0681742 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05073299 0,06813672 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05073299 0,06809928 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05073299 0,06806189 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,05073299 0,06802453 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,05073299 0,06798722 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05073299 0,06794994 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,05073299 0,06791271 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05073299 0,06787552 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05073299 0,06783837 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05073299 0,06780125 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05073299 0,06776418 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05073299 0,06772715 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05073299 0,06769017 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05073299 0,06765322 ! membrane depolarization GO:0051899 45 24 0,000 0,05073299 0,06761631 ! pallium development GO:0021543 56 24 0,000 0,05073299 0,06757944 ! oogenesis GO:0048477 44 24 0,000 0,05073299 0,06754261 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05073299 0,06750582 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05073299 0,06746908 ! platelet activation GO:0030168 41 24 0,000 0,05073299 0,06743237 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05073299 0,0673957 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05073299 0,06735907 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05073299 0,06732248 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05073299 0,06728594 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05073299 0,06724943 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05073299 0,06721296 ! regulation of amine transport GO:0051952 41 24 0,000 0,05073299 0,06717653 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,05073299 0,06714014 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0527908 0,06982563 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0527908 0,06978784 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0527908 0,0697501 ! phototransduction GO:0007602 37 25 0,000 0,0527908 0,0697124 ! keratinization GO:0031424 37 25 0,000 0,0527908 0,06967473 ! vasculogenesis GO:0001570 49 25 0,000 0,0527908 0,06963711 ! vacuole organization GO:0007033 49 25 0,000 0,0527908 0,06959953 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0527908 0,06956199 ! receptor metabolic process GO:0043112 53 25 0,000 0,0527908 0,06952449 ! chromosome condensation GO:0030261 48 25 0,000 0,0527908 0,06948703 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,0527908 0,06944961 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0527908 0,06941224 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0527908 0,0693749 ! immunoglobulin production GO:0002377 62 25 0,000 0,0527908 0,0693376 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0527908 0,06930034 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0527908 0,06926312 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0527908 0,06922594 ! liver development GO:0001889 55 25 0,000 0,0527908 0,06918881 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05484421 0,07184151 ! myelination GO:0042552 50 26 0,000 0,05484421 0,07180301 ! initiation of viral infection GO:0019059 60 26 0,000 0,05484421 0,07176455 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05484421 0,07172613 ! molting cycle process GO:0022404 52 26 0,000 0,05484421 0,07168776 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05484421 0,07164942 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05484421 0,07161113 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05484421 0,07157287 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05484421 0,07153466 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05484421 0,07149649 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,05484421 0,07145836 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05484421 0,07142026 ! digestive system process GO:0022600 49 26 0,000 0,05484421 0,07138221 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05484421 0,0713442 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,05484421 0,07130624 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05484421 0,07126831 ! neural crest cell development GO:0014032 59 26 0,000 0,05484421 0,07123042 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05484421 0,07119257 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05484421 0,07115476 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05484421 0,07111699 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05484421 0,07107927 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05484421 0,07104158 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05484421 0,07100393 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,05484421 0,07096632 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05484421 0,07092875 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05484421 0,07089123 ! blastocyst development GO:0001824 50 26 0,000 0,05484421 0,07085374 ! telomere organization GO:0032200 46 26 0,000 0,05484421 0,07081629 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05484421 0,07077888 ! neural tube closure GO:0001843 58 26 0,000 0,05484421 0,07074151 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05484421 0,07070418 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05484421 0,07066689 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05484421 0,07062963 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05689323 0,0732298 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05689323 0,07319124 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05689323 0,07315272 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05689323 0,07311424 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,05689323 0,0730758 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05689323 0,0730374 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05689323 0,07299904 ! iron ion transport GO:0006826 65 27 0,000 0,05689323 0,07296072 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,05689323 0,07292244 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05689323 0,0728842 ! tube lumen formation GO:0035148 59 27 0,000 0,05689323 0,072846 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05689323 0,07280784 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,05689323 0,07276972 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,05689323 0,07273164 ! response to toxin GO:0009636 49 27 0,000 0,05689323 0,0726936 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,05689323 0,0726556 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,05689323 0,07261764 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05689323 0,07257972 ! leukocyte proliferation GO:0070661 59 27 0,000 0,05689323 0,07254184 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,05689323 0,072504 ! neuron fate commitment GO:0048663 52 28 0,000 0,05893786 0,07507049 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05893786 0,07503137 ! protein amino acid acylation GO:0043543 59 28 0,000 0,05893786 0,07499229 ! vesicle docking GO:0048278 55 28 0,000 0,05893786 0,07495326 ! circadian rhythm GO:0007623 56 28 0,000 0,05893786 0,07491426 ! dendrite development GO:0016358 67 28 0,000 0,05893786 0,0748753 ! fat cell differentiation GO:0045444 57 28 0,000 0,05893786 0,07483638 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05893786 0,07479751 ! sperm motility GO:0030317 37 28 0,000 0,05893786 0,07475867 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05893786 0,07471988 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05893786 0,07468112 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05893786 0,07464241 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,05893786 0,07460373 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05893786 0,0745651 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05893786 0,0745265 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05893786 0,07448795 ! glutathione metabolic process GO:0006749 42 28 0,000 0,05893786 0,07444943 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,05893786 0,07441096 ! lipid oxidation GO:0034440 48 28 0,000 0,05893786 0,07437252 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,05893786 0,07433413 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05893786 0,07429577 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,06097812 0,07682803 ! translational initiation GO:0006413 66 29 0,000 0,06097812 0,07678843 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,06097812 0,07674887 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,06097812 0,07670935 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,06097812 0,07666987 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,06097812 0,07663043 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,06097812 0,07659103 ! primary neural tube formation GO:0014020 61 29 0,000 0,06097812 0,07655167 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,06097812 0,07651235 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,06097812 0,07647308 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,06097812 0,07643384 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,06097812 0,07639464 ! somitogenesis GO:0001756 52 29 0,000 0,06097812 0,07635549 ! synaptogenesis GO:0007416 46 29 0,000 0,06097812 0,07631637 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,06097812 0,07627729 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,06097812 0,07623826 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,06097812 0,07619926 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,06097812 0,0761603 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06301401 0,07866287 ! phenol metabolic process GO:0018958 56 30 0,000 0,06301401 0,07862269 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,06301401 0,07858256 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,06301401 0,07854247 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06301401 0,07850241 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06301401 0,0784624 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06301401 0,07842243 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06301401 0,0783825 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,06301401 0,07834261 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06301401 0,07830276 ! myofibril assembly GO:0030239 50 30 0,000 0,06301401 0,07826296 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,06301401 0,07822319 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,06301401 0,07818346 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06301401 0,07814377 ! cell fate determination GO:0001709 64 30 0,000 0,06301401 0,07810413 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,06301401 0,07806452 ! phospholipid transport GO:0015914 65 30 0,000 0,06301401 0,07802495 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06301401 0,07798543 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06301401 0,07794594 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06301401 0,0779065 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06301401 0,07786709 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06301401 0,07782772 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,06301401 0,0777884 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06504555 0,08025569 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06504555 0,08021518 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06504555 0,08017471 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06504555 0,08013428 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06504555 0,08009389 ! ovulation cycle process GO:0022602 55 31 0,000 0,06504555 0,08005354 ! peptide transport GO:0015833 60 31 0,000 0,06504555 0,08001323 ! male gonad development GO:0008584 56 31 0,000 0,06504555 0,07997296 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06504555 0,07993273 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06504555 0,07989255 ! detection of light stimulus GO:0009583 44 31 0,000 0,06504555 0,0798524 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,06504555 0,07981229 ! natural killer cell activation GO:0030101 50 31 0,000 0,06504555 0,07977223 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06504555 0,0797322 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06504555 0,07969221 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06504555 0,07965227 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06504555 0,07961236 ! eye morphogenesis GO:0048592 65 31 0,000 0,06504555 0,0795725 ! response to heat GO:0009408 54 31 0,000 0,06504555 0,07953267 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06504555 0,07949288 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06707274 0,08192935 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06707274 0,0818884 ! collagen metabolic process GO:0032963 49 32 0,000 0,06707274 0,0818475 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,06707274 0,08180664 ! spindle organization GO:0007051 50 32 0,000 0,06707274 0,08176581 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,06707274 0,08172503 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06707274 0,08168429 ! metanephros development GO:0001656 81 32 0,000 0,06707274 0,08164359 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06707274 0,08160293 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,06707274 0,08156232 ! muscle cell development GO:0055001 52 32 0,000 0,06707274 0,08152174 ! mesoderm formation GO:0001707 73 32 0,000 0,06707274 0,0814812 ! ovulation cycle GO:0042698 57 32 0,000 0,06707274 0,0814407 ! peripheral nervous system development GO:0007422 68 32 0,000 0,06707274 0,08140024 ! BMP signaling pathway GO:0030509 71 32 0,000 0,06707274 0,08135983 ! hindbrain development GO:0030902 65 32 0,000 0,06707274 0,08131945 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,06707274 0,08127911 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,06707274 0,08123882 ! gene silencing GO:0016458 71 32 0,000 0,06707274 0,08119856 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06909558 0,083606 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,06909558 0,08356461 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06909558 0,08352326 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06909558 0,08348195 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,06909558 0,08344069 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06909558 0,08339946 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,06909558 0,08335828 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06909558 0,08331713 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06909558 0,08327603 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06909558 0,08323497 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06909558 0,08319394 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,0711141 0,08558215 ! glial cell differentiation GO:0010001 67 34 0,000 0,0711141 0,08554001 ! post-embryonic development GO:0009791 76 34 0,000 0,0711141 0,08549791 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,0711141 0,08545586 ! cholesterol transport GO:0030301 62 34 0,000 0,0711141 0,08541384 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,0711141 0,08537187 ! spliceosome assembly GO:0000245 75 34 0,000 0,0711141 0,08532994 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,0711141 0,08528805 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,0711141 0,0852462 ! formation of primary germ layer GO:0001704 76 34 0,000 0,0711141 0,08520439 ! cell fate specification GO:0001708 56 34 0,000 0,0711141 0,08516262 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,0711141 0,0851209 ! adult locomotory behavior GO:0008344 62 34 0,000 0,0711141 0,08507921 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0731283 0,08744613 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0731283 0,08740335 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,0731283 0,08736061 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0731283 0,08731791 ! membrane docking GO:0022406 69 35 0,000 0,0731283 0,08727525 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0731283 0,08723264 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0731283 0,08719006 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0731283 0,08714753 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,0731283 0,08710504 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0731283 0,08706259 ! telencephalon development GO:0021537 81 35 0,000 0,0731283 0,08702019 ! sterol transport GO:0015918 63 35 0,000 0,0731283 0,08697782 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0731283 0,0869355 ! placenta development GO:0001890 53 35 0,000 0,0731283 0,08689321 ! vesicle localization GO:0051648 70 35 0,000 0,0731283 0,08685097 ! regulation of muscle development GO:0048634 82 36 0,000 0,07513819 0,08919466 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07513819 0,08915134 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07513819 0,08910806 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07513819 0,08906482 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07513819 0,08902163 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07513819 0,08897848 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07513819 0,08893537 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07513819 0,0888923 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07513819 0,08884927 ! aerobic respiration GO:0009060 56 36 0,000 0,07513819 0,08880629 ! cytokine production GO:0001816 68 36 0,000 0,07513819 0,08876335 ! embryonic organ development GO:0048568 67 36 0,000 0,07513819 0,08872044 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07513819 0,08867758 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07714378 0,0910006 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,07714378 0,09095668 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,07714378 0,09091281 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07714378 0,09086897 ! odontogenesis GO:0042476 74 37 0,000 0,07714378 0,09082518 ! actomyosin structure organization GO:0031032 68 37 0,000 0,07714378 0,09078143 ! tissue remodeling GO:0048771 78 37 0,000 0,07714378 0,09073772 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07714378 0,09069406 ! female gonad development GO:0008585 71 37 0,000 0,07714378 0,09065043 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07714378 0,09060685 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,07714378 0,09056331 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,07714378 0,09051981 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,07714378 0,09047636 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07914507 0,09277899 ! meiosis I GO:0007127 74 38 0,000 0,07914507 0,09273449 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07914507 0,09269003 ! organic anion transport GO:0015711 82 38 0,000 0,07914507 0,09264562 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07914507 0,09260125 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,07914507 0,09255692 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,07914507 0,09251264 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07914507 0,09246839 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,07914507 0,09242419 ! regulation of protein stability GO:0031647 77 38 0,000 0,07914507 0,09238003 ! spermatid development GO:0007286 69 38 0,000 0,07914507 0,09233592 ! glycogen metabolic process GO:0005977 63 38 0,000 0,07914507 0,09229184 ! pigment metabolic process GO:0042440 87 38 0,000 0,07914507 0,09224781 ! neural tube formation GO:0001841 79 38 0,000 0,07914507 0,09220382 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,08114208 0,09448527 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,08114208 0,09444026 ! negative regulation of binding GO:0051100 71 39 0,000 0,08114208 0,09439529 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,08114208 0,09435036 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,08114208 0,09430547 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,08114208 0,09426063 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,08114208 0,09421583 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,08114208 0,09417107 ! glucan metabolic process GO:0044042 64 39 0,000 0,08114208 0,09412635 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,08313482 0,09639219 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,08313482 0,09634647 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,08313482 0,09630078 ! learning GO:0007612 82 40 0,000 0,08313482 0,09625514 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,08313482 0,09620955 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,08313482 0,09616399 ! lipid homeostasis GO:0055088 75 40 0,000 0,08313482 0,09611848 ! mismatch repair GO:0006298 58 40 0,000 0,08313482 0,09607302 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,08313482 0,09602759 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,08313482 0,09598221 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,08313482 0,09593687 ! RNA export from nucleus GO:0006405 61 41 0,000 0,08512328 0,09818517 ! mRNA catabolic process GO:0006402 79 41 0,000 0,08512328 0,09813883 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,08512328 0,09809254 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,08512328 0,09804629 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,08512328 0,09800009 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,08512328 0,09795393 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,08512328 0,09790781 ! feeding behavior GO:0007631 69 41 0,000 0,08512328 0,09786173 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,08512328 0,0978157 ! mesenchymal cell development GO:0014031 94 41 0,000 0,08512328 0,09776972 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,08512328 0,09772377 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,08512328 0,09767787 ! spermatid differentiation GO:0048515 73 41 0,000 0,08512328 0,09763201 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,08512328 0,0975862 ! RNA modification GO:0009451 64 41 0,000 0,08512328 0,09754042 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,0871075 0,09976728 ! ear morphogenesis GO:0042471 64 42 0,000 0,0871075 0,09972053 ! organic ether metabolic process GO:0018904 59 42 0,000 0,0871075 0,09967383 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,0871075 0,09962716 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,0871075 0,09958054 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,0871075 0,09953396 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,0871075 0,09948743 ! regulation of protein secretion GO:0050708 77 42 0,000 0,0871075 0,09944094 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,0871075 0,0993945 ! cytokinesis GO:0000910 84 42 0,000 0,0871075 0,09934809 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,0871075 0,09930173 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,08908746 0,10151151 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,08908746 0,10146418 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,08908746 0,1014169 ! regulation of tube size GO:0035150 76 43 0,000 0,08908746 0,10136967 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,08908746 0,10132247 ! glucose transport GO:0015758 66 43 0,000 0,08908746 0,10127532 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,08908746 0,10122822 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,08908746 0,10118116 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,08908746 0,10113414 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,08908746 0,10108717 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,08908746 0,10104024 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,08908746 0,10099335 ! segmentation GO:0035282 78 43 0,000 0,08908746 0,10094651 ! ion transmembrane transport GO:0034220 79 43 0,000 0,08908746 0,10089971 ! neuron migration GO:0001764 85 43 0,000 0,08908746 0,10085295 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,09106319 0,10304186 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,09106319 0,10299415 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,09106319 0,10294649 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,09106319 0,10289888 ! hexose transport GO:0008645 68 44 0,000 0,09106319 0,1028513 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,09106319 0,10280378 ! striated muscle contraction GO:0006941 85 44 0,000 0,09106319 0,10275629 ! phagocytosis GO:0006909 105 44 0,000 0,09106319 0,10270885 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,09106319 0,10266145 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,09303469 0,10483567 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,09303469 0,10478734 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,09303469 0,10473905 ! biopolymer methylation GO:0043414 91 45 0,000 0,09303469 0,10469081 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,09303469 0,10464261 ! female gamete generation GO:0007292 71 45 0,000 0,09303469 0,10459445 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,09303469 0,10454634 ! polyol metabolic process GO:0019751 77 45 0,000 0,09303469 0,10449827 ! developmental growth GO:0048589 88 45 0,000 0,09303469 0,10445025 ! maintenance of location in cell GO:0051651 101 45 0,000 0,09303469 0,10440227 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,09500196 0,10656097 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,09500196 0,10651207 ! glycolysis GO:0006096 71 46 0,000 0,09500196 0,10646321 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,09500196 0,10641439 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,09500196 0,10636562 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,09500196 0,1063169 ! pigmentation GO:0043473 103 46 0,000 0,09500196 0,10626822 ! cell growth GO:0016049 90 46 0,000 0,09500196 0,10621959 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,09500196 0,10617099 ! neural tube development GO:0021915 91 47 0,000 0,09696503 0,1083153 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,09696503 0,10826579 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09892389 0,11040249 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,09892389 0,11035208 ! cellular component disassembly GO:0022411 89 48 0,000 0,09892389 0,11030171 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,09892389 0,11025139 ! endosome transport GO:0016197 127 48 0,000 0,09892389 0,11020112 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,09892389 0,11015089 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09892389 0,11010071 ! male sex differentiation GO:0046661 93 48 0,000 0,09892389 0,11005057 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09892389 0,11000048 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,09892389 0,10995044 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,09892389 0,10990044 ! methylation GO:0032259 97 48 0,000 0,09892389 0,10985048 ! response to calcium ion GO:0051592 94 49 0,000 0,10087855 0,11197015 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,10087855 0,1119193 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,10087855 0,1118685 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,10087855 0,11181774 ! JNK cascade GO:0007254 106 49 0,000 0,10087855 0,11176703 ! protein homooligomerization GO:0051260 84 49 0,000 0,10087855 0,11171637 ! regulation of action potential GO:0001508 102 50 0,000 0,10282904 0,1138248 ! regulation of ion transport GO:0043269 86 50 0,000 0,10282904 0,11377325 ! endocrine system development GO:0035270 109 50 0,000 0,10282904 0,11372175 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,10282904 0,11367029 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,10282904 0,11361888 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,10282904 0,11356751 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,10282904 0,11351619 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,10282904 0,11346492 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,10282904 0,1134137 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,10477534 0,11550819 ! viral infectious cycle GO:0019058 104 51 0,000 0,10477534 0,11545609 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,10477534 0,11540404 ! peptide metabolic process GO:0006518 80 51 0,000 0,10477534 0,11535203 ! response to temperature stimulus GO:0009266 84 51 0,000 0,10477534 0,11530007 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,10477534 0,11524816 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,10477534 0,11519629 ! positive regulation of binding GO:0051099 88 52 0,000 0,10671748 0,11727881 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,10671748 0,11722608 ! Notch signaling pathway GO:0007219 111 52 0,000 0,10671748 0,11717339 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,10671748 0,11712076 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,10671748 0,11706816 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,10671748 0,11701562 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,10671748 0,11696312 ! excretion GO:0007588 87 52 0,000 0,10671748 0,11691067 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,10671748 0,11685827 ! histone modification GO:0016570 104 52 0,000 0,10671748 0,11680591 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,10671748 0,11675361 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,10671748 0,11670134 ! amino acid activation GO:0043038 98 52 0,000 0,10671748 0,11664913 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10865546 0,11871435 ! inner ear development GO:0048839 89 53 0,000 0,10865546 0,11866128 ! chromatin remodeling GO:0006338 122 53 0,000 0,10865546 0,11860826 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10865546 0,11855529 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10865546 0,11850236 ! vesicle organization GO:0016050 127 53 0,000 0,10865546 0,11844948 ! synapse organization GO:0050808 102 53 0,000 0,10865546 0,11839665 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,11058929 0,12045012 ! regulation of translational initiation GO:0006446 87 54 0,000 0,11058929 0,12039645 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,11058929 0,12034282 ! neuromuscular process GO:0050905 107 54 0,000 0,11058929 0,12028924 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,11058929 0,12023571 ! membrane fusion GO:0006944 122 54 0,000 0,11058929 0,12018222 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,11058929 0,12012878 ! covalent chromatin modification GO:0016569 115 54 0,000 0,11058929 0,12007539 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,11058929 0,12002205 ! regulation of cell shape GO:0008360 142 54 0,000 0,11058929 0,11996875 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,11058929 0,1199155 ! RNA catabolic process GO:0006401 103 55 0,000 0,11251898 0,1219538 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,11251898 0,12189971 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,11251898 0,12184568 ! cell recognition GO:0008037 98 55 0,000 0,11251898 0,1217917 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,11251898 0,12173776 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,11251898 0,12168387 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,11444453 0,1237115 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,11444453 0,12365678 ! glucose catabolic process GO:0006007 88 56 0,000 0,11444453 0,12360212 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,11444453 0,1235475 ! RNA elongation GO:0006354 90 56 0,000 0,11444453 0,12349293 ! chloride transport GO:0006821 102 57 0,000 0,11636596 0,12551084 ! muscle fiber development GO:0048747 131 57 0,000 0,11636596 0,12545545 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,11636596 0,12540011 ! regulation of actin filament length GO:0030832 118 58 0,000 0,11828328 0,12741008 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,11828328 0,12735392 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,11828328 0,12729782 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,11828328 0,12724177 ! gastrulation GO:0007369 122 58 0,000 0,11828328 0,12718576 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,11828328 0,12712981 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,11828328 0,1270739 ! maintenance of location GO:0051235 124 58 0,000 0,11828328 0,12701804 ! nuclear export GO:0051168 110 59 0,000 0,12019649 0,12901583 ! establishment of organelle localization GO:0051656 122 59 0,000 0,12019649 0,12895917 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,1221056 0,13094995 ! DNA catabolic process GO:0006308 94 60 0,000 0,1221056 0,13089249 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,1221056 0,13083508 ! adult behavior GO:0030534 104 60 0,000 0,1221056 0,13077772 ! kidney development GO:0001822 133 60 0,000 0,1221056 0,13072042 ! positive regulation of secretion GO:0051047 110 61 0,000 0,12401063 0,13270169 ! regulation of cellular component size GO:0032535 125 61 0,000 0,12401063 0,13264359 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,12401063 0,13258554 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,12401063 0,13252754 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,12401063 0,13246959 ! camera-type eye development GO:0043010 126 61 0,000 0,12401063 0,1324117 ! proton transport GO:0015992 117 61 0,000 0,12401063 0,13235385 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,12591157 0,134324 ! tRNA processing GO:0008033 102 62 0,000 0,12591157 0,13426537 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,12780844 0,13622863 ! regulation of mitosis GO:0007088 112 63 0,000 0,12780844 0,13616922 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,12780844 0,13610986 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,12780844 0,13605056 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,12780844 0,1359913 ! hydrogen transport GO:0006818 121 64 0,000 0,12970125 0,13794521 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,12970125 0,13788519 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,12970125 0,13782521 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,13159001 0,13977147 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,13159001 0,13971073 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,13159001 0,13965004 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,13159001 0,1395894 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,13159001 0,13952881 ! ear development GO:0043583 114 66 0,000 0,13347471 0,14146582 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,13347471 0,14140448 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,13347471 0,14134318 ! gonad development GO:0008406 115 66 0,000 0,13347471 0,14128194 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,13347471 0,14122076 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,13535538 0,14314857 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,13535538 0,14308663 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,13535538 0,14302474 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,13535538 0,14296291 ! secondary metabolic process GO:0019748 125 67 0,000 0,13535538 0,14290113 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,13535538 0,1428394 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,13723203 0,14475727 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,13723203 0,1446948 ! hexose catabolic process GO:0019320 113 68 0,000 0,13723203 0,14463237 ! extracellular matrix organization GO:0030198 146 68 0,000 0,13723203 0,14457001 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,13723203 0,14450769 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,13723203 0,14444543 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,13723203 0,14438322 ! adaptive immune response GO:0002250 126 68 0,000 0,13723203 0,14432107 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,13723203 0,14425897 ! cell projection assembly GO:0030031 138 68 0,000 0,13723203 0,14419692 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,13910465 0,14610174 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,13910465 0,14603896 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,13910465 0,14597623 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,13910465 0,14591355 ! single fertilization GO:0007338 83 69 0,000 0,13910465 0,14585093 ! cell redox homeostasis GO:0045454 114 70 0,000 0,14097326 0,14774675 ! germ cell development GO:0007281 133 70 0,000 0,14097326 0,14768339 ! activation of immune response GO:0002253 120 70 0,000 0,14097326 0,14762009 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,14097326 0,14755684 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,14283787 0,1494445 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,14283787 0,14938052 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,14283787 0,14931661 ! appendage morphogenesis GO:0035107 150 72 0,000 0,14469848 0,15119691 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,14469848 0,15113227 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,14469848 0,15106768 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,14469848 0,15100315 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,14469848 0,15093868 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,14469848 0,15087426 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,14469848 0,15080989 ! appendage development GO:0048736 151 73 0,000 0,1465551 0,15267979 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,1465551 0,15261471 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,1465551 0,15254969 ! regulation of immune effector process GO:0002697 156 73 0,000 0,1465551 0,15248472 ! amino acid transport GO:0006865 148 74 0,000 0,14840775 0,15434659 ! organelle localization GO:0051640 155 74 0,000 0,14840775 0,15428091 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,15025643 0,15613631 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,15025643 0,15606992 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,15025643 0,15600359 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,15025643 0,15593732 ! eye development GO:0001654 155 75 0,000 0,15025643 0,15587111 ! axon guidance GO:0007411 162 75 0,000 0,15025643 0,15580495 ! rhythmic process GO:0048511 142 75 0,000 0,15025643 0,15573884 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,15210115 0,15758401 ! learning or memory GO:0007611 161 76 0,000 0,15210115 0,15751721 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,15210115 0,15745047 ! regulation of blood pressure GO:0008217 134 76 0,000 0,15210115 0,15738378 ! amine catabolic process GO:0009310 136 77 0,000 0,15394191 0,15922103 ! neurotransmitter transport GO:0006836 142 77 0,000 0,15394191 0,15915365 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,15394191 0,15908633 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,15394191 0,15901906 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,15394191 0,15895185 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,15577873 0,1607805 ! antigen processing and presentation GO:0019882 117 78 0,000 0,15577873 0,1607126 ! fertilization GO:0009566 99 78 0,000 0,15577873 0,16064476 ! blood coagulation GO:0007596 151 79 0,000 0,15761161 0,16246632 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,15761161 0,16239779 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,15761161 0,16232933 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,15761161 0,16226092 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,15761161 0,16219257 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,15761161 0,16212428 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,15944057 0,16393658 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,15944057 0,16386761 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,15944057 0,1637987 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,15944057 0,16372985 ! meiosis GO:0007126 143 81 0,000 0,1612656 0,1655344 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,1612656 0,16546488 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,1612656 0,16539541 ! meiotic cell cycle GO:0051321 144 82 0,000 0,16308673 0,16719298 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,16490395 0,16898505 ! exocytosis GO:0006887 153 83 0,000 0,16490395 0,16891419 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,16490395 0,1688434 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,16490395 0,16877266 ! inorganic anion transport GO:0015698 156 83 0,000 0,16490395 0,16870199 ! response to metal ion GO:0010038 158 84 0,000 0,16671728 0,17048569 ! response to nutrient GO:0007584 135 84 0,000 0,16671728 0,17041435 ! digestion GO:0007586 130 84 0,000 0,16671728 0,17034308 ! regulation of ligase activity GO:0051340 147 84 0,000 0,16671728 0,17027187 ! hemostasis GO:0007599 165 85 0,000 0,16852672 0,17204796 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,16852672 0,17197609 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,16852672 0,17190429 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,16852672 0,17183254 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,16852672 0,17176086 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,17033228 0,17352867 ! regulation of lyase activity GO:0051339 169 86 0,000 0,17033228 0,17345634 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,17213397 0,17521804 ! alcohol catabolic process GO:0046164 142 87 0,000 0,17213397 0,17514506 ! nucleosome assembly GO:0006334 126 87 0,000 0,17213397 0,17507215 ! regulation of protein transport GO:0051223 165 87 0,000 0,17213397 0,17499929 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,1739318 0,17675349 ! amine biosynthetic process GO:0009309 146 88 0,000 0,1739318 0,17668 ! sensory perception of smell GO:0007608 117 88 0,000 0,1739318 0,17660657 ! chromatin assembly GO:0031497 128 88 0,000 0,1739318 0,17653319 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,1739318 0,17645988 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,17572578 0,17820593 ! regulation of DNA binding GO:0051101 167 89 0,000 0,17572578 0,17813198 ! cellular defense response GO:0006968 123 89 0,000 0,17572578 0,1780581 ! regulation of neurological system process GO:0031644 175 89 0,000 0,17572578 0,17798428 ! response to inorganic substance GO:0010035 173 90 0,000 0,17751591 0,17972291 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,17751591 0,17964846 ! response to unfolded protein GO:0006986 139 90 0,000 0,17751591 0,17957407 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,17751591 0,17949974 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,17930221 0,18123098 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,17930221 0,18115603 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,18108467 0,18288129 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,18286332 0,18460127 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,18286332 0,18452502 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,18286332 0,18444884 ! vitamin metabolic process GO:0006766 153 93 0,000 0,18286332 0,18437271 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,18463815 0,18608539 ! female pregnancy GO:0007565 166 94 0,000 0,18463815 0,18600866 ! sterol metabolic process GO:0016125 166 94 0,000 0,18463815 0,18593198 ! regulation of membrane potential GO:0042391 179 94 0,000 0,18463815 0,18585537 ! nucleosome organization GO:0034728 143 95 0,000 0,18640917 0,18756079 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,18640917 0,18748358 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,18640917 0,18740642 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,18640917 0,18732933 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,18640917 0,18725231 ! sex differentiation GO:0007548 171 96 0,000 0,1881764 0,18894983 ! response to protein stimulus GO:0051789 158 96 0,000 0,1881764 0,1888722 ! regulation of T cell activation GO:0050863 175 96 0,000 0,1881764 0,18879464 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,18993984 0,19048564 ! transcription initiation GO:0006352 171 97 0,000 0,18993984 0,19040748 ! regulation of protein localization GO:0032880 188 97 0,000 0,18993984 0,19032938 ! forebrain development GO:0030900 210 98 0,000 0,1916995 0,19201389 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,1916995 0,1919352 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,19520751 0,19536745 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,19520751 0,19528744 ! positive regulation of immune response GO:0050778 175 100 0,000 0,19520751 0,19520751