pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6592-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 5,000 1,149E-14 2,766E-11 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 5,000 3,419E-13 4,113E-10 ! positive regulation of hormone secretion GO:0046887 32 19 5,000 4,306E-11 3,453E-08 ! carbohydrate homeostasis GO:0033500 53 38 6,000 6,312E-11 3,797E-08 GO:0042593|glucose homeostasis, ! regulation of intracellular protein transport GO:0033157 80 42 6,000 1,334E-10 6,419E-08 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 6,000 2,616E-10 1,049E-07 ! regulation of insulin secretion GO:0050796 37 25 5,000 2,763E-10 9,496E-08 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 7,228E-10 2,174E-07 ! regulation of peptide secretion GO:0002791 47 29 5,000 7,326E-10 1,959E-07 ! regulation of intracellular transport GO:0032386 101 57 6,000 1,252E-09 3,012E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 2,162E-09 4,73E-07 ! organ growth GO:0035265 15 7 3,000 5,032E-09 1,009E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 5,032E-09 9,313E-07 GO:0046676|negative regulation of insulin secretion, ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 5,032E-09 8,648E-07 ! regulation of hormone secretion GO:0046883 62 40 5,000 5,737E-09 9,203E-07 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 1,004E-08 1,509E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 1,004E-08 1,42E-06 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 1,802E-08 2,408E-06 ! regulation of protein transport GO:0051223 154 87 6,000 2,538E-08 3,214E-06 GO:0070201|regulation of establishment of protein localization, ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 2,995E-08 3,603E-06 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 4,693E-08 5,377E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of protein localization GO:0032880 176 97 6,000 5,422E-08 5,93E-06 ! positive regulation of secretion GO:0051047 95 59 5,000 6,38E-08 6,674E-06 ! DNA damage checkpoint GO:0000077 71 33 4,000 1,077E-07 1,08E-05 ! cell cycle checkpoint GO:0000075 137 69 5,000 1,65E-07 1,588E-05 ! DNA integrity checkpoint GO:0031570 75 36 4,000 1,697E-07 1,571E-05 ! negative regulation of hormone secretion GO:0046888 25 17 3,000 3,33E-07 2,968E-05 ! endothelial cell migration GO:0043542 28 17 3,000 3,33E-07 2,862E-05 ! inositol metabolic process GO:0006020 28 17 3,000 3,33E-07 2,763E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 3,33E-07 2,671E-05 ! cardiac muscle tissue development GO:0048738 31 17 3,000 3,33E-07 2,585E-05 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 4,644E-07 3,492E-05 ! myoblast cell fate commitment GO:0048625 16 6 2,000 8,41E-07 6,132E-05 ! positive regulation of MAP kinase activity GO:0043406 160 93 5,000 9,799E-07 6,934E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 1,219E-06 8,38E-05 GO:0010810|regulation of cell-substrate adhesion, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,778E-06 1,188E-04 ! lipid modification GO:0030258 97 57 4,000 1,778E-06 1,156E-04 ! DNA damage response, signal transduction GO:0042770 128 60 4,000 2,299E-06 1,456E-04 ! ER overload response GO:0006983 12 8 2,000 2,343E-06 1,445E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 2,343E-06 1,409E-04 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 3,702E-06 2,172E-04 ! activation of MAPK activity GO:0000187 115 67 4,000 3,987E-06 2,284E-04 ! triglyceride metabolic process GO:0006641 43 31 3,000 4,239E-06 2,372E-04 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 5,697E-06 3,115E-04 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 6,85E-06 3,663E-04 ! negative regulation of secretion GO:0051048 63 35 3,000 6,978E-06 3,65E-04 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 6,978E-06 3,572E-04 ! neutral lipid metabolic process GO:0006638 50 35 3,000 6,978E-06 3,498E-04 GO:0006639|acylglycerol metabolic process, ! glycerol ether metabolic process GO:0006662 53 37 3,000 8,754E-06 4,298E-04 ! regulation of protein stability GO:0031647 73 37 3,000 8,754E-06 4,212E-04 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 9,11E-06 4,298E-04 ! organic ether metabolic process GO:0018904 55 39 3,000 1,084E-05 5,017E-04 ! negative regulation of transport GO:0051051 153 84 4,000 1,216E-05 5,518E-04 ! hormone-mediated signaling GO:0009755 74 41 3,000 1,328E-05 5,916E-04 ! polyol metabolic process GO:0019751 66 41 3,000 1,328E-05 5,809E-04 ! G1/S transition checkpoint GO:0031575 40 15 2,000 1,87E-05 8,033E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,87E-05 7,892E-04 ! negative regulation of cell migration GO:0030336 115 46 3,000 2,111E-05 8,757E-04 ! myoblast differentiation GO:0045445 45 17 2,000 2,78E-05 1,134E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,78E-05 1,115E-03 ! cell cycle arrest GO:0007050 213 100 4,000 2,835E-05 1,118E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 3,000 3,189E-05 1,238E-03 ! regulation of multicellular organism growth GO:0040014 85 55 3,000 4,306E-05 1,644E-03 ! RNA elongation GO:0006354 79 55 3,000 4,306E-05 1,619E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 4,306E-05 1,594E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 4,625E-05 1,686E-03 ! pancreas development GO:0031016 35 20 2,000 4,625E-05 1,661E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 4,625E-05 1,636E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 6,074E-05 2,118E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 6,216E-05 2,136E-03 ! multicellular organism reproduction GO:0032504 111 64 3,000 7,829E-05 2,653E-03 GO:0048609|reproductive process in a multicellular organism, ! protein tetramerization GO:0051262 52 24 2,000 8,127E-05 2,716E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 9,212E-05 3,036E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 9,927E-05 3,228E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,039E-04 3,332E-03 ! fat cell differentiation GO:0045444 50 27 2,000 1,166E-04 3,69E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,219E-04 3,808E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,219E-04 3,759E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,219E-04 3,712E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 1,219E-04 3,665E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,302E-04 3,868E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 3,000 1,692E-04 4,966E-03 ! protein oligomerization GO:0051259 139 78 3,000 1,692E-04 4,906E-03 ! male sex determination GO:0030238 15 6 1,000 1,824E-04 5,224E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,824E-04 5,162E-03 ! muscle cell differentiation GO:0042692 159 80 3,000 1,867E-04 5,222E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,951E-04 5,396E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,547E-04 6,965E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,547E-04 6,887E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,547E-04 6,81E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,547E-04 6,735E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,547E-04 6,662E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,547E-04 6,59E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 2,78E-04 7,117E-03 ! regulation of cell adhesion GO:0030155 212 89 3,000 2,812E-04 7,123E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 3,018E-04 7,564E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 3,268E-04 8,107E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,389E-04 8,32E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,389E-04 8,236E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,389E-04 8,153E-03 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 3,389E-04 8,073E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 3,389E-04 7,994E-03 ! transcription initiation GO:0006352 153 94 3,000 3,466E-04 8,096E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 3,808E-04 8,81E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! hormone metabolic process GO:0042445 157 97 3,000 3,906E-04 8,95E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 4,347E-04 9,867E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 4,347E-04 9,775E-03 ! Golgi to endosome transport GO:0006895 23 9 1,000 4,347E-04 9,684E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 4,347E-04 9,595E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 4,347E-04 9,508E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 4,347E-04 9,422E-03 ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 4,347E-04 9,338E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 4,347E-04 9,256E-03 ! icosanoid secretion GO:0032309 15 9 1,000 4,347E-04 9,174E-03 GO:0050482|arachidonic acid secretion, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 5,421E-04 0,01134216 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 5,421E-04 0,01124438 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 5,421E-04 0,01114827 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 5,762E-04 0,01174906 ! response to insulin stimulus GO:0032868 95 46 2,000 5,762E-04 0,01165033 ! positive regulation of protein transport GO:0051222 72 46 2,000 5,762E-04 0,01155324 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 6,611E-04 0,01314496 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 6,611E-04 0,01303722 ! regulation of intracellular pH GO:0051453 19 11 1,000 6,611E-04 0,01293123 ! acid secretion GO:0046717 18 11 1,000 6,611E-04 0,01282694 ! cardiac cell differentiation GO:0035051 31 11 1,000 6,611E-04 0,01272433 ! regulation of embryonic development GO:0045995 27 11 1,000 6,611E-04 0,01262334 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 7,915E-04 0,01499421 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 7,915E-04 0,01487707 ! virus-host interaction GO:0019048 29 12 1,000 7,915E-04 0,01476174 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 7,915E-04 0,01464819 ! response to UV GO:0009411 104 53 2,000 8,735E-04 0,01604297 ! cGMP metabolic process GO:0046068 18 13 1,000 9,332E-04 0,01701006 GO:0006182|cGMP biosynthetic process, ! response to X-ray GO:0010165 25 13 1,000 9,332E-04 0,01688216 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 9,332E-04 0,01675618 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 9,332E-04 0,01663206 ! regulation of cellular pH GO:0030641 22 13 1,000 9,332E-04 0,01650976 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 9,332E-04 0,01638925 ! heart morphogenesis GO:0003007 97 55 2,000 9,733E-04 0,01696858 ! skeletal muscle fiber development GO:0048741 111 56 2,000 1,026E-03 0,01775477 ! regulation of DNA replication GO:0006275 101 56 2,000 1,026E-03 0,01762795 ! muscle fiber development GO:0048747 112 57 2,000 1,08E-03 0,01842829 ! positive regulation of cell migration GO:0030335 126 57 2,000 1,08E-03 0,01829851 ! regulation of mRNA processing GO:0050684 24 14 1,000 1,086E-03 0,01827647 ! response to gamma radiation GO:0010332 28 14 1,000 1,086E-03 0,01814955 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,086E-03 0,01802438 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,25E-03 0,02060751 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 1,315E-03 0,02152133 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,426E-03 0,02317988 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,426E-03 0,02302431 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,426E-03 0,02287081 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,426E-03 0,02271935 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 1,443E-03 0,02284863 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,511E-03 0,0237551 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 1,000 1,612E-03 0,02518909 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,81E-03 0,02809034 ! response to retinoic acid GO:0032526 26 18 1,000 1,81E-03 0,02791027 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,81E-03 0,0277325 ! long-chain fatty acid transport GO:0015909 31 18 1,000 1,81E-03 0,02755698 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,81E-03 0,02738366 ! lipid phosphorylation GO:0046834 35 19 1,000 2,018E-03 0,03034426 ! response to vitamin A GO:0033189 27 19 1,000 2,018E-03 0,03015579 ! regulation of caspase activity GO:0043281 122 72 2,000 2,119E-03 0,03146818 ! response to vitamin GO:0033273 31 20 1,000 2,237E-03 0,03301946 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,237E-03 0,03281812 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,237E-03 0,03261922 ! cellular response to starvation GO:0009267 33 20 1,000 2,237E-03 0,03242272 ! peptidyl-serine modification GO:0018209 43 20 1,000 2,237E-03 0,03222857 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,237E-03 0,03203674 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 2,291E-03 0,03262048 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 2,000 2,381E-03 0,03369405 ! smooth muscle contraction GO:0006939 46 21 1,000 2,467E-03 0,0347081 ! cell aging GO:0007569 44 21 1,000 2,467E-03 0,03450631 ! regulation of vasoconstriction GO:0019229 39 21 1,000 2,467E-03 0,03430685 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 2,467E-03 0,03410969 ! cytosolic calcium ion homeostasis GO:0051480 135 76 2,000 2,472E-03 0,03399001 ! regulation of catabolic process GO:0009894 161 76 2,000 2,472E-03 0,03379688 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,707E-03 0,03680022 ! keratinization GO:0031424 28 22 1,000 2,707E-03 0,03659348 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,707E-03 0,03638905 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,707E-03 0,03618688 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 2,707E-03 0,03598696 GO:0060415|muscle tissue morphogenesis, ! regulation of peptidase activity GO:0052547 134 79 2,000 2,76E-03 0,03648499 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,958E-03 0,03889425 ! sex determination GO:0007530 47 23 1,000 2,958E-03 0,03868287 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,958E-03 0,03847377 ! fatty acid transport GO:0015908 44 23 1,000 2,958E-03 0,03826693 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 3,22E-03 0,04142743 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 3,22E-03 0,04120708 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 3,22E-03 0,04098905 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 3,22E-03 0,04077332 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 3,492E-03 0,04398588 ! negative regulation of DNA replication GO:0008156 42 25 1,000 3,492E-03 0,04375679 ! response to starvation GO:0042594 42 25 1,000 3,492E-03 0,04353007 ! negative regulation of cell development GO:0010721 73 25 1,000 3,492E-03 0,04330569 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 3,492E-03 0,0430836 ! cellular response to nutrient levels GO:0031669 41 25 1,000 3,492E-03 0,04286379 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 3,774E-03 0,04609434 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 3,774E-03 0,04586154 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 4,067E-03 0,04916883 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 4,067E-03 0,04892299 ! mitochondrial membrane organization GO:0007006 57 27 1,000 4,067E-03 0,04867959 ! base-excision repair GO:0006284 41 27 1,000 4,067E-03 0,0484386 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 1,000 4,067E-03 0,04819999 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 4,37E-03 0,0515351 ! regulation of pH GO:0006885 43 29 1,000 4,683E-03 0,05495656 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 4,683E-03 0,05468978 ! tissue homeostasis GO:0001894 48 29 1,000 4,683E-03 0,05442558 GO:0048871|multicellular organismal homeostasis, ! regulation of DNA metabolic process GO:0051052 178 97 2,000 4,916E-03 0,05686592 ! protein ubiquitination GO:0016567 217 97 2,000 4,916E-03 0,05659384 ! skeletal muscle tissue development GO:0007519 186 99 2,000 5,203E-03 0,05961607 GO:0060538|skeletal muscle organ development, ! response to ionizing radiation GO:0010212 65 32 1,000 5,681E-03 0,06478372 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 5,681E-03 0,06447814 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 6,034E-03 0,06815975 ! negative regulation of protein transport GO:0051224 69 33 1,000 6,034E-03 0,06784124 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 6,397E-03 0,07158224 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 6,769E-03 0,07539658 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 6,769E-03 0,07504913 ! calcium-mediated signaling GO:0019722 62 35 1,000 6,769E-03 0,07470486 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 7,542E-03 0,08285798 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 7,542E-03 0,08248136 ! cyclic nucleotide metabolic process GO:0009187 63 37 1,000 7,542E-03 0,08210814 ! glycogen metabolic process GO:0005977 61 37 1,000 7,542E-03 0,08173828 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 7,943E-03 0,08569649 ! glucan metabolic process GO:0044042 62 38 1,000 7,943E-03 0,08531391 GO:0006073|cellular glucan metabolic process, ! T cell differentiation GO:0030217 81 41 1,000 9,201E-03 0,09839442 ! keratinocyte differentiation GO:0030216 62 41 1,000 9,201E-03 0,09795905 ! monocarboxylic acid transport GO:0015718 85 42 1,000 9,64E-03 0,10217058 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01008673 0,10644153 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01008673 0,10597672 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01008673 0,10551596 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01054299 0,10981137 ! double-strand break repair GO:0006302 81 44 1,000 0,01054299 0,10933805 ! B cell differentiation GO:0030183 107 44 1,000 0,01054299 0,10886879 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,01100824 0,1131873 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,01148242 0,11756048 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,01148242 0,11706234 ! endosome transport GO:0016197 108 47 1,000 0,01196547 0,12147222 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01196547 0,12096183 ! protein homooligomerization GO:0051260 76 47 1,000 0,01196547 0,12045571 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,01245731 0,12488449 ! mitochondrial transport GO:0006839 82 48 1,000 0,01245731 0,1243663 ! activation of caspase activity GO:0006919 84 48 1,000 0,01245731 0,12385239 ! positive regulation of growth GO:0045927 90 52 1,000 0,01451127 0,14367947 ! amino acid activation GO:0043038 92 52 1,000 0,01451127 0,14309062 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,01504608 0,14775867 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01504608 0,14715803 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,0155893 0,15185364 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01614085 0,15659223 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01614085 0,15596335 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01614085 0,15533949 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,01614085 0,15472061 ! aging GO:0007568 103 55 1,000 0,01614085 0,15410664 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01670066 0,15882134 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01726869 0,16357664 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01747575 0,1648888 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01747575 0,1642447 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01747575 0,16360562 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01747575 0,16297149 ! neuron fate determination GO:0048664 7 5 0,000 0,01747575 0,16234225 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01747575 0,16171786 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01747575 0,16109825 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01747575 0,16048337 ! polyol transport GO:0015791 12 5 0,000 0,01747575 0,15987317 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01747575 0,15926759 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01747575 0,15866658 ! response to superoxide GO:0000303 10 5 0,000 0,01747575 0,15807009 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01747575 0,15747807 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01747575 0,15689046 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01747575 0,15630723 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01747575 0,15572831 ! female meiosis GO:0007143 7 5 0,000 0,01747575 0,15515367 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01747575 0,15458325 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01747575 0,15401701 ! cobalt ion transport GO:0006824 11 5 0,000 0,01747575 0,15345491 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01747575 0,15289689 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01747575 0,15234291 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01747575 0,15179294 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01747575 0,15124692 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01747575 0,15070482 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01747575 0,15016659 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01747575 0,14963219 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01747575 0,14910157 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01747575 0,14857471 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01747575 0,14805156 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01747575 0,14753208 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01747575 0,14701624 ! negative chemotaxis GO:0050919 14 5 0,000 0,01747575 0,14650399 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01747575 0,14599529 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01747575 0,14549012 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01747575 0,14498843 ! behavioral response to pain GO:0048266 9 5 0,000 0,01747575 0,14449019 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01747575 0,14399536 ! Notch receptor processing GO:0007220 8 5 0,000 0,01747575 0,1435039 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01747575 0,1430158 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01747575 0,142531 ! micturition GO:0060073 9 5 0,000 0,01747575 0,14204947 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01747575 0,14157119 ! copulation GO:0007620 9 5 0,000 0,01747575 0,14109612 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01747575 0,14062423 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01747575 0,14015548 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01747575 0,13968985 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01747575 0,1392273 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01747575 0,1387678 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01747575 0,13831133 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01747575 0,13785785 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01747575 0,13740733 ! grooming behavior GO:0007625 6 5 0,000 0,01747575 0,13695975 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01747575 0,13651508 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01747575 0,13607328 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01747575 0,13563434 ! response to protozoan GO:0001562 10 5 0,000 0,01747575 0,13519821 ! lymph vessel development GO:0001945 10 5 0,000 0,01747575 0,13476488 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01747575 0,13433433 ! endochondral ossification GO:0001958 16 5 0,000 0,01747575 0,13390651 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01747575 0,13348141 ! parathyroid gland development GO:0060017 13 5 0,000 0,01747575 0,133059 ! anagen GO:0042640 6 5 0,000 0,01747575 0,13263926 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01747575 0,13222215 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01747575 0,13180766 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01747575 0,13139576 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01747575 0,13098643 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01747575 0,13057964 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01747575 0,13017537 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01747575 0,12977359 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01747575 0,12937429 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01747575 0,12897744 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01747575 0,12858301 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01747575 0,12819099 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01747575 0,12780135 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01747575 0,12741407 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01747575 0,12702914 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01747575 0,12664652 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01747575 0,1262662 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01747575 0,12588816 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01747575 0,12551237 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01747575 0,12513882 ! histidine catabolic process GO:0006548 6 5 0,000 0,01747575 0,12476749 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01747575 0,12439835 ! microvillus organization GO:0032528 7 5 0,000 0,01747575 0,1240314 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01747575 0,1236666 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01747575 0,12330394 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01747575 0,1229434 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01747575 0,12258497 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01747575 0,12222862 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01747575 0,12187433 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01747575 0,12152209 ! polyol catabolic process GO:0046174 7 5 0,000 0,01747575 0,12117188 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01747575 0,12082369 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01747575 0,12047749 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01747575 0,12013327 ! muscle cell migration GO:0014812 8 5 0,000 0,01747575 0,11979101 ! mitochondrial fission GO:0000266 8 5 0,000 0,01747575 0,11945069 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01747575 0,11911231 ! mRNA transcription GO:0009299 9 5 0,000 0,01747575 0,11877583 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01747575 0,11844125 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01747575 0,11810855 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01747575 0,11777771 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01747575 0,11744873 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01747575 0,11712157 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01747575 0,11679623 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01747575 0,1164727 ! response to food GO:0032094 6 5 0,000 0,01747575 0,11615095 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01747575 0,11583098 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01747575 0,11551276 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01747575 0,11519628 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01747575 0,11488154 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01747575 0,11456851 ! forebrain neuron development GO:0021884 13 5 0,000 0,01747575 0,11425718 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01747575 0,11394754 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01747575 0,11363958 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01747575 0,11333327 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01747575 0,11302861 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01747575 0,11272559 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01747575 0,11242418 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01747575 0,11212438 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01747575 0,11182618 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01747575 0,11152956 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01747575 0,11123451 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01747575 0,11094101 ! basic amino acid transport GO:0015802 11 5 0,000 0,01747575 0,11064906 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01747575 0,11035865 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01747575 0,11006975 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01747575 0,10978236 ! depyrimidination GO:0045008 10 5 0,000 0,01747575 0,10949647 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01747575 0,10921206 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01747575 0,10892913 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01747575 0,10864766 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01747575 0,10836764 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01747575 0,10808906 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01747575 0,10781191 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01747575 0,10753617 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01747575 0,10726185 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01747575 0,10698892 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01747575 0,10671737 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01747575 0,1064472 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01747575 0,10617839 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01747575 0,10591094 ! response to arsenic GO:0046685 10 5 0,000 0,01747575 0,10564483 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01747575 0,10538006 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01747575 0,10511661 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01747575 0,10485447 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01747575 0,10459364 ! response to cadmium ion GO:0046686 7 5 0,000 0,01747575 0,1043341 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01747575 0,10407585 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01747575 0,10381887 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01747575 0,10356316 ! decidualization GO:0046697 11 5 0,000 0,01747575 0,10330871 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01747575 0,1030555 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01747575 0,10280353 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01747575 0,10255279 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01747575 0,10230327 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01747575 0,10205496 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01747575 0,10180785 ! neural tube patterning GO:0021532 7 5 0,000 0,01747575 0,10156194 ! embryonic cleavage GO:0040016 6 5 0,000 0,01747575 0,10131721 ! peroxisome fission GO:0016559 5 5 0,000 0,01747575 0,10107366 ! histone demethylation GO:0016577 10 5 0,000 0,01747575 0,10083128 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01747575 0,10059006 ! mitotic recombination GO:0006312 9 5 0,000 0,01747575 0,10034999 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01747575 0,10011106 ! metaphase plate congression GO:0051310 7 5 0,000 0,01747575 0,09987326 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01747575 0,0996366 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01747575 0,09940105 ! enteric nervous system development GO:0048484 8 5 0,000 0,01747575 0,09916661 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01747575 0,09893328 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01747575 0,09870104 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01747575 0,09846989 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01747575 0,09823982 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01747575 0,09801083 ! plasminogen activation GO:0031639 5 5 0,000 0,01747575 0,09778289 ! B cell homeostasis GO:0001782 13 5 0,000 0,01747575 0,09755602 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01747575 0,09733019 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01747575 0,09710541 ! metaphase GO:0051323 8 5 0,000 0,01747575 0,09688167 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01747575 0,09665895 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01747575 0,09643726 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01747575 0,09621658 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01747575 0,0959969 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01747575 0,09577823 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01747575 0,09556055 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01747575 0,09534386 ! response to redox state GO:0051775 5 5 0,000 0,01747575 0,09512815 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01747575 0,09491342 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01747575 0,09469965 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01747575 0,09448684 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01747575 0,09427499 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01747575 0,09406408 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01747575 0,09385412 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01747575 0,09364509 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01747575 0,09343699 ! striatum development GO:0021756 9 5 0,000 0,01747575 0,09322981 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01747575 0,09302355 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01747575 0,0928182 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01747575 0,09261375 ! glial cell migration GO:0008347 11 5 0,000 0,01747575 0,09241021 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01747575 0,09220755 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01747575 0,09200579 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01747575 0,0918049 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01747575 0,09160489 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01747575 0,09140575 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01747575 0,09120747 ! neuroprotection GO:0043526 6 5 0,000 0,01747575 0,09101005 ! neural plate development GO:0001840 8 5 0,000 0,01747575 0,09081349 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01747575 0,09061777 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01747575 0,09042289 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01747575 0,09022885 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01747575 0,09003564 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01747575 0,08984326 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01747575 0,08965169 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01747575 0,08946094 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01747575 0,08927101 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01747575 0,08908187 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01747575 0,08889354 ! spindle assembly GO:0051225 6 5 0,000 0,01747575 0,088706 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01747575 0,08851925 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01747575 0,08833329 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01747575 0,0881481 ! drug metabolic process GO:0017144 6 5 0,000 0,01747575 0,08796369 ! stem cell division GO:0017145 11 5 0,000 0,01747575 0,08778005 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01747575 0,08759717 ! organ regeneration GO:0031100 7 5 0,000 0,01747575 0,08741506 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01747575 0,0872337 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01747575 0,08705309 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01747575 0,08687323 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01784486 0,08852521 ! viral reproductive process GO:0022415 126 62 1,000 0,0202297 0,10014952 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,02084565 0,1029869 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02093442 0,10321355 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02093442 0,10300248 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02093442 0,10279227 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02093442 0,10258292 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02093442 0,10237441 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02093442 0,10216676 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02093442 0,10195994 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02093442 0,10175396 ! sleep GO:0030431 13 6 0,000 0,02093442 0,10154881 ! response to oxygen radical GO:0000305 11 6 0,000 0,02093442 0,10134449 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02093442 0,10114099 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02093442 0,1009383 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02093442 0,10073642 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02093442 0,10053535 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02093442 0,10033508 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02093442 0,10013561 ! forebrain regionalization GO:0021871 8 6 0,000 0,02093442 0,09993693 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02093442 0,09973903 ! male meiosis GO:0007140 7 6 0,000 0,02093442 0,09954192 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02093442 0,09934559 ! response to zinc ion GO:0010043 9 6 0,000 0,02093442 0,09915002 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02093442 0,09895523 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02093442 0,0987612 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02093442 0,09856793 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02093442 0,09837541 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02093442 0,09818365 ! malate metabolic process GO:0006108 11 6 0,000 0,02093442 0,09799263 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02093442 0,09780235 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02093442 0,09761281 ! protein refolding GO:0042026 15 6 0,000 0,02093442 0,09742401 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02093442 0,09723593 ! opsonization GO:0008228 8 6 0,000 0,02093442 0,09704858 ! mating behavior GO:0007617 7 6 0,000 0,02093442 0,09686195 ! neuron remodeling GO:0016322 15 6 0,000 0,02093442 0,09667603 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02093442 0,09649083 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02093442 0,09630633 ! equilibrioception GO:0050957 14 6 0,000 0,02093442 0,09612254 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02093442 0,09593945 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02093442 0,09575706 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02093442 0,09557535 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02093442 0,09539434 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02093442 0,09521401 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02093442 0,09503436 ! toxin metabolic process GO:0009404 11 6 0,000 0,02093442 0,09485539 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02093442 0,09467709 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02093442 0,09449946 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02093442 0,09432249 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02093442 0,09414619 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02093442 0,09397054 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02093442 0,09379555 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02093442 0,09362121 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02093442 0,09344752 ! thymic T cell selection GO:0045061 12 6 0,000 0,02093442 0,09327447 ! protein lipoylation GO:0009249 10 6 0,000 0,02093442 0,09310206 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02093442 0,09293028 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02093442 0,09275914 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02093442 0,09258862 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02093442 0,09241874 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02093442 0,09224947 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02093442 0,09208083 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02093442 0,0919128 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02093442 0,09174538 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02093442 0,09157857 ! hyperosmotic response GO:0006972 9 6 0,000 0,02093442 0,09141236 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02093442 0,09124676 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02093442 0,09108176 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02093442 0,09091735 ! urea metabolic process GO:0019627 7 6 0,000 0,02093442 0,09075354 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02093442 0,09059031 ! neutrophil activation GO:0042119 8 6 0,000 0,02093442 0,09042767 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02093442 0,09026561 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02093442 0,09010414 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02093442 0,08994324 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02093442 0,08978291 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02093442 0,08962315 ! neuron apoptosis GO:0051402 9 6 0,000 0,02093442 0,08946396 ! nucleoside salvage GO:0043174 9 6 0,000 0,02093442 0,08930534 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02093442 0,08914728 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02093442 0,08898977 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02093442 0,08883283 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02093442 0,08867643 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02093442 0,08852058 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02093442 0,08836528 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02093442 0,08821053 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02093442 0,08805631 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02093442 0,08790264 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02093442 0,0877495 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02093442 0,08759689 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02093442 0,08744481 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02093442 0,08729326 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02093442 0,08714224 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02093442 0,08699173 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02093442 0,08684174 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02093442 0,08669228 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02093442 0,08654332 ! neural nucleus development GO:0048857 14 6 0,000 0,02093442 0,08639487 ! response to UV-C GO:0010225 11 6 0,000 0,02093442 0,08624694 ! astrocyte development GO:0014002 15 6 0,000 0,02093442 0,08609951 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02093442 0,08595258 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02093442 0,08580615 ! interaction with symbiont GO:0051702 13 6 0,000 0,02093442 0,08566022 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02093442 0,08551479 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02093442 0,08536985 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02093442 0,0852254 ! response to copper ion GO:0046688 10 6 0,000 0,02093442 0,08508144 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02093442 0,08493796 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02093442 0,08479497 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02093442 0,08465246 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02093442 0,08451042 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02093442 0,08436886 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02093442 0,08422778 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02093442 0,08408717 ! hair follicle maturation GO:0048820 7 6 0,000 0,02093442 0,08394702 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02093442 0,08380734 ! Schwann cell development GO:0014044 15 6 0,000 0,02093442 0,08366813 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02093442 0,08352937 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02093442 0,08339108 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02093442 0,08325324 ! subpallium development GO:0021544 10 6 0,000 0,02093442 0,08311586 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02093442 0,08297893 ! histone ubiquitination GO:0016574 8 6 0,000 0,02093442 0,08284245 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02093442 0,08270642 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02093442 0,08257084 ! G2 phase GO:0051319 16 6 0,000 0,02093442 0,0824357 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02093442 0,082301 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02093442 0,08216674 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02093442 0,08203292 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02093442 0,08189953 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02093442 0,08176658 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02093442 0,08163406 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02093442 0,08150196 ! receptor internalization GO:0031623 10 6 0,000 0,02093442 0,08137029 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02093442 0,08123905 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02093442 0,08110823 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02093442 0,08097783 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02093442 0,08084785 ! protein deubiquitination GO:0016579 14 6 0,000 0,02093442 0,08071829 ! protein destabilization GO:0031648 9 6 0,000 0,02093442 0,08058914 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02093442 0,0804604 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02093442 0,08033208 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02093442 0,08020416 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02093442 0,08007665 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02093442 0,07994954 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02093442 0,07982284 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02093442 0,07969654 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02093442 0,07957064 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02093442 0,07944513 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02093442 0,07932002 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02093442 0,0791953 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02093442 0,07907098 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02093442 0,07894704 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02093442 0,07882349 ! catecholamine transport GO:0051937 9 6 0,000 0,02093442 0,07870033 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02093442 0,07857755 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02093442 0,07845516 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02093442 0,07833314 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02093442 0,07821151 ! maternal placenta development GO:0001893 12 6 0,000 0,02093442 0,07809025 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02093442 0,07796937 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02093442 0,07784886 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02093442 0,07772872 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02093442 0,07760896 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02093442 0,07748956 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02093442 0,07737053 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02093442 0,07725186 ! actin filament organization GO:0007015 148 66 1,000 0,02273984 0,08378569 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,02338649 0,08603654 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,02338649 0,08590518 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,02338649 0,08577423 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,02404067 0,08803934 ! viral reproduction GO:0016032 134 68 1,000 0,02404067 0,08790554 ! regulation of lipase activity GO:0060191 130 68 1,000 0,02404067 0,08777215 ! tRNA transcription GO:0009304 14 7 0,000 0,02438103 0,08887994 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02438103 0,08874548 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02438103 0,08861142 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02438103 0,08847777 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02438103 0,08834452 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02438103 0,08821167 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02438103 0,08807922 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02438103 0,08794717 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02438103 0,08781551 ! prostate gland development GO:0030850 13 7 0,000 0,02438103 0,08768425 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02438103 0,08755338 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02438103 0,08742289 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02438103 0,0872928 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02438103 0,08716309 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02438103 0,08703377 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02438103 0,08690483 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02438103 0,08677627 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02438103 0,0866481 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02438103 0,0865203 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02438103 0,08639287 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02438103 0,08626583 ! glycolipid transport GO:0046836 10 7 0,000 0,02438103 0,08613915 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02438103 0,08601285 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02438103 0,08588691 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02438103 0,08576135 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02438103 0,08563615 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02438103 0,08551131 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02438103 0,08538684 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02438103 0,08526274 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02438103 0,08513899 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02438103 0,0850156 ! mRNA stabilization GO:0048255 18 7 0,000 0,02438103 0,08489256 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02438103 0,08476989 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02438103 0,08464756 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02438103 0,08452559 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02438103 0,08440397 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02438103 0,0842827 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02438103 0,08416178 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02438103 0,08404121 ! lipoprotein transport GO:0042953 14 7 0,000 0,02438103 0,08392098 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02438103 0,08380109 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02438103 0,08368154 ! rhythmic behavior GO:0007622 15 7 0,000 0,02438103 0,08356234 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02438103 0,08344347 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02438103 0,08332495 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02438103 0,08320675 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02438103 0,0830889 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02438103 0,08297137 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02438103 0,08285418 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02438103 0,08273732 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02438103 0,08262079 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02438103 0,08250459 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02438103 0,08238871 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02438103 0,08227316 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02438103 0,08215793 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02438103 0,08204302 ! spinal cord patterning GO:0021511 13 7 0,000 0,02438103 0,08192844 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02438103 0,08181417 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02438103 0,08170023 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02438103 0,0815866 ! adrenal gland development GO:0030325 17 7 0,000 0,02438103 0,08147328 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02438103 0,08136028 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02438103 0,08124759 ! ovulation GO:0030728 9 7 0,000 0,02438103 0,08113522 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02438103 0,08102315 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02438103 0,0809114 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02438103 0,08079995 ! microtubule nucleation GO:0007020 20 7 0,000 0,02438103 0,08068881 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02438103 0,08057797 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02438103 0,08046744 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02438103 0,08035721 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02438103 0,08024728 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02438103 0,08013765 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02438103 0,08002832 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02438103 0,07991929 ! galactose metabolic process GO:0006012 13 7 0,000 0,02438103 0,07981056 ! vesicle fusion GO:0006906 17 7 0,000 0,02438103 0,07970212 ! response to dietary excess GO:0002021 8 7 0,000 0,02438103 0,07959398 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02438103 0,07948613 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02438103 0,07937857 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02438103 0,0792713 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02438103 0,07916432 ! purine salvage GO:0043101 10 7 0,000 0,02438103 0,07905763 ! nucleoside transport GO:0015858 8 7 0,000 0,02438103 0,07895123 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02438103 0,07884511 ! parturition GO:0007567 14 7 0,000 0,02438103 0,07873928 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02438103 0,07863373 ! rRNA modification GO:0000154 14 7 0,000 0,02438103 0,07852846 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02438103 0,07842348 ! spindle checkpoint GO:0031577 15 7 0,000 0,02438103 0,07831877 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02438103 0,07821435 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02438103 0,0781102 ! macrophage differentiation GO:0030225 11 7 0,000 0,02438103 0,07800633 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02438103 0,07790274 ! centrosome duplication GO:0051298 13 7 0,000 0,02438103 0,07779942 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02438103 0,07769637 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02438103 0,0775936 ! fibrinolysis GO:0042730 10 7 0,000 0,02438103 0,0774911 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02438103 0,07738887 ! eating behavior GO:0042755 7 7 0,000 0,02438103 0,07728691 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02438103 0,07718521 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02438103 0,07708379 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02438103 0,07698263 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02438103 0,07688173 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02438103 0,0767811 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02438103 0,07668073 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02438103 0,07658063 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02438103 0,07648078 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02438103 0,0763812 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02438103 0,07628187 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02438103 0,07618281 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02438103 0,076084 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02438103 0,07598544 ! regulation of meiosis GO:0040020 12 7 0,000 0,02438103 0,07588714 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02438103 0,0757891 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02438103 0,07569131 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02438103 0,07559377 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02438103 0,07549648 ! transcription termination GO:0006353 13 7 0,000 0,02438103 0,07539944 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02438103 0,07530265 ! anaphase GO:0051322 17 7 0,000 0,02438103 0,0752061 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02438103 0,07510981 ! axonal fasciculation GO:0007413 18 7 0,000 0,02438103 0,07501376 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02438103 0,07491796 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02438103 0,0748224 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02438103 0,07472709 ! diuresis GO:0030146 12 7 0,000 0,02438103 0,07463201 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02438103 0,07453718 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02438103 0,07444259 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02438103 0,07434824 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02438103 0,07425413 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02438103 0,07416026 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02438103 0,07406662 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02438103 0,07397322 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02438103 0,07388005 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02438103 0,07378712 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02438103 0,07369442 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02438103 0,07360196 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02438103 0,07350973 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02438103 0,07341772 ! lymph node development GO:0048535 10 7 0,000 0,02438103 0,07332595 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02438103 0,07323441 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02438103 0,07314309 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02438103 0,07305201 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02438103 0,07296115 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02438103 0,07287051 ! adult feeding behavior GO:0008343 9 7 0,000 0,02438103 0,0727801 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02438103 0,07268992 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02438103 0,07259995 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02438103 0,07251021 ! muscle adaptation GO:0043500 14 7 0,000 0,02438103 0,07242069 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02438103 0,0723314 ! retina homeostasis GO:0001895 12 7 0,000 0,02438103 0,07224232 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02438103 0,07215346 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02438103 0,07206482 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02438103 0,07197639 ! protein prenylation GO:0018342 18 7 0,000 0,02438103 0,07188819 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02438103 0,0718002 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02438103 0,07171242 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02438103 0,07162486 ! negative regulation of cell size GO:0045792 134 69 1,000 0,02470231 0,07248019 ! B cell activation GO:0042113 160 71 1,000 0,02604776 0,07633483 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,02673144 0,07824312 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02781563 0,08131761 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02781563 0,08121892 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02781563 0,08112048 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02781563 0,08102227 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02781563 0,0809243 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02781563 0,08082656 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02781563 0,08072906 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02781563 0,0806318 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02781563 0,08053477 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02781563 0,08043797 ! meiotic prophase I GO:0007128 13 8 0,000 0,02781563 0,08034141 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02781563 0,08024508 ! oligopeptide transport GO:0006857 15 8 0,000 0,02781563 0,08014897 ! UTP metabolic process GO:0046051 8 8 0,000 0,02781563 0,0800531 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02781563 0,07995746 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02781563 0,07986205 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02781563 0,07976686 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02781563 0,0796719 ! succinate metabolic process GO:0006105 14 8 0,000 0,02781563 0,07957716 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02781563 0,07948265 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02781563 0,07938837 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02781563 0,07929431 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02781563 0,07920047 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02781563 0,07910685 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02781563 0,07901345 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02781563 0,07892028 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02781563 0,07882732 ! reflex GO:0060004 16 8 0,000 0,02781563 0,07873458 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02781563 0,07864206 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02781563 0,07854976 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02781563 0,07845767 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02781563 0,0783658 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02781563 0,07827414 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02781563 0,0781827 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02781563 0,07809147 ! pigment granule organization GO:0048753 16 8 0,000 0,02781563 0,07800046 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02781563 0,07790966 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02781563 0,07781906 ! histidine metabolic process GO:0006547 16 8 0,000 0,02781563 0,07772868 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02781563 0,07763851 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02781563 0,07754854 ! glycine catabolic process GO:0006546 13 8 0,000 0,02781563 0,07745879 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02781563 0,07736924 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02781563 0,0772799 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02781563 0,07719077 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02781563 0,07710184 ! melanin metabolic process GO:0006582 15 8 0,000 0,02781563 0,07701311 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02781563 0,07692459 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02781563 0,07683627 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02781563 0,07674816 ! macrophage activation GO:0042116 12 8 0,000 0,02781563 0,07666024 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02781563 0,07657253 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02781563 0,07648502 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02781563 0,07639771 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02781563 0,0763106 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02781563 0,07622368 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02781563 0,07613697 ! osteoblast development GO:0002076 16 8 0,000 0,02781563 0,07605045 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02781563 0,07596412 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02781563 0,075878 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02781563 0,07579207 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02781563 0,07570633 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02781563 0,07562078 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02781563 0,07553543 ! response to UV-B GO:0010224 16 8 0,000 0,02781563 0,07545027 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02781563 0,07536531 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02781563 0,07528053 ! intermediate filament organization GO:0045109 12 8 0,000 0,02781563 0,07519595 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02781563 0,07511155 ! cellular extravasation GO:0045123 12 8 0,000 0,02781563 0,07502735 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02781563 0,07494333 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02781563 0,0748595 ! response to antibiotic GO:0046677 11 8 0,000 0,02781563 0,07477586 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02781563 0,0746924 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02781563 0,07460913 ! DNA topological change GO:0006265 12 8 0,000 0,02781563 0,07452605 ! response to tropane GO:0014073 15 8 0,000 0,02781563 0,07444315 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02781563 0,07436044 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02781563 0,07427791 ! melanosome transport GO:0032402 13 8 0,000 0,02781563 0,07419556 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02781563 0,07411339 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02781563 0,07403141 ! mast cell activation GO:0045576 14 8 0,000 0,02781563 0,07394961 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02781563 0,07386798 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02781563 0,07378654 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02781563 0,07370528 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02781563 0,0736242 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02781563 0,07354329 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02781563 0,07346256 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02781563 0,07338201 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02781563 0,07330164 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02781563 0,07322144 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02781563 0,07314141 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02781563 0,07306157 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02781563 0,07298189 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02781563 0,07290239 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02781563 0,07282306 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02781563 0,07274391 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02781563 0,07266492 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02781563 0,07258611 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02781563 0,07250747 ! hormone catabolic process GO:0042447 17 8 0,000 0,02781563 0,072429 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02781563 0,0723507 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02781563 0,07227256 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02781563 0,0721946 ! ATP catabolic process GO:0006200 11 8 0,000 0,02781563 0,0721168 ! blastocyst growth GO:0001832 19 8 0,000 0,02781563 0,07203918 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02781563 0,07196171 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02781563 0,07188442 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02781563 0,07180729 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02781563 0,07173033 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02781563 0,07165353 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02781563 0,07157689 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02781563 0,07150042 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02781563 0,07142411 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02781563 0,07134797 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02781563 0,07127198 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02781563 0,07119616 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02781563 0,0711205 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02781563 0,071045 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02781563 0,07096966 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02781563 0,07089449 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02781563 0,07081946 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02812044 0,07151985 GO:0090046|regulation of transcription regulator activity, ! organelle localization GO:0051640 136 74 1,000 0,02812044 0,07144432 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02882564 0,07315873 ! axon extension GO:0048675 15 9 0,000 0,03123824 0,07919832 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03123824 0,07911496 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03123824 0,07903176 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03123824 0,07894875 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03123824 0,07886591 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03123824 0,07878324 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03123824 0,07870074 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03123824 0,07861842 ! phosphate transport GO:0006817 19 9 0,000 0,03123824 0,07853627 ! reproductive behavior GO:0019098 19 9 0,000 0,03123824 0,07845429 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03123824 0,07837248 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03123824 0,07829084 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03123824 0,07820937 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 0,000 0,03123824 0,07812807 ! RNA methylation GO:0001510 15 9 0,000 0,03123824 0,07804694 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03123824 0,07796598 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03123824 0,07788519 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03123824 0,07780456 ! artery development GO:0060840 24 9 0,000 0,03123824 0,0777241 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03123824 0,07764381 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03123824 0,07756368 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03123824 0,07748372 ! chemosensory behavior GO:0007635 20 9 0,000 0,03123824 0,07740392 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03123824 0,07732429 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03123824 0,07724482 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03123824 0,07716551 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03123824 0,07708637 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03123824 0,07700739 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03123824 0,07692856 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03123824 0,07684991 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03123824 0,07677141 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03123824 0,07669307 ! protein targeting to ER GO:0045047 22 9 0,000 0,03123824 0,07661489 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03123824 0,07653687 ! T cell selection GO:0045058 23 9 0,000 0,03123824 0,07645901 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03123824 0,07638131 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03123824 0,07630376 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03123824 0,07622638 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03123824 0,07614915 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03123824 0,07607207 ! mannose metabolic process GO:0006013 13 9 0,000 0,03123824 0,07599515 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03123824 0,07591839 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03123824 0,07584178 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03123824 0,07576533 ! receptor clustering GO:0043113 18 9 0,000 0,03123824 0,07568903 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03123824 0,07561289 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03123824 0,07553689 ! ruffle organization GO:0031529 15 9 0,000 0,03123824 0,07546105 ! retinol metabolic process GO:0042572 18 9 0,000 0,03123824 0,07538536 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03123824 0,07530983 ! behavioral fear response GO:0001662 22 9 0,000 0,03123824 0,07523444 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03123824 0,07515921 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03123824 0,07508412 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03123824 0,07500919 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03123824 0,0749344 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03123824 0,07485977 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03123824 0,07478528 ! segment specification GO:0007379 13 9 0,000 0,03123824 0,07471094 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03123824 0,07463675 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03123824 0,07456271 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03123824 0,07448881 ! response to amine stimulus GO:0014075 13 9 0,000 0,03123824 0,07441506 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03123824 0,07434145 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03123824 0,07426799 ! erythrocyte development GO:0048821 15 9 0,000 0,03123824 0,07419468 ! gas homeostasis GO:0033483 16 9 0,000 0,03123824 0,07412151 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03123824 0,07404848 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03123824 0,0739756 ! renal water homeostasis GO:0003091 14 9 0,000 0,03123824 0,07390286 ! postreplication repair GO:0006301 22 9 0,000 0,03123824 0,07383026 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03123824 0,07375781 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03123824 0,0736855 ! induction of an organ GO:0001759 14 9 0,000 0,03123824 0,07361333 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03123824 0,0735413 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03123824 0,07346941 ! regulation of cell division GO:0051302 15 9 0,000 0,03123824 0,07339766 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03123824 0,07332606 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03123824 0,07325459 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03123824 0,07318326 ! sterol catabolic process GO:0016127 11 9 0,000 0,03123824 0,07311207 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03123824 0,07304102 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03123824 0,0729701 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03123824 0,07289933 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03123824 0,07282869 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03123824 0,07275819 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03123824 0,07268782 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03123824 0,07261759 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03123824 0,0725475 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03123824 0,07247754 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03123824 0,07240771 ! purine base metabolic process GO:0006144 21 9 0,000 0,03123824 0,07233802 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03123824 0,07226847 ! pigment granule transport GO:0051904 17 9 0,000 0,03123824 0,07219905 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03123824 0,07212976 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03123824 0,0720606 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03123824 0,07199158 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03123824 0,07192269 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03123824 0,07185393 ! mitochondrion localization GO:0051646 15 9 0,000 0,03123824 0,0717853 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,03171641 0,07281458 ! protein import into nucleus GO:0006606 158 80 1,000 0,03245631 0,07444222 ! T cell activation GO:0042110 168 81 1,000 0,03320299 0,07608228 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,03320299 0,07600989 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 1,000 0,03320299 0,07593764 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,03395638 0,07758695 ! response to drug GO:0042493 143 82 1,000 0,03395638 0,07751334 ! response to nutrient GO:0007584 125 82 1,000 0,03395638 0,07743986 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03464892 0,07894442 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03464892 0,07886973 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03464892 0,07879518 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03464892 0,07872078 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03464892 0,07864651 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03464892 0,07857239 ! synapsis GO:0007129 13 10 0,000 0,03464892 0,0784984 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03464892 0,07842456 ! N-glycan processing GO:0006491 20 10 0,000 0,03464892 0,07835085 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03464892 0,07827728 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03464892 0,07820385 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03464892 0,07813056 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03464892 0,0780574 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03464892 0,07798438 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03464892 0,0779115 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03464892 0,07783875 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03464892 0,07776614 ! androgen metabolic process GO:0008209 17 10 0,000 0,03464892 0,07769367 ! phospholipid efflux GO:0033700 16 10 0,000 0,03464892 0,07762133 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03464892 0,07754912 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03464892 0,07747705 ! lung alveolus development GO:0048286 26 10 0,000 0,03464892 0,07740511 ! pathogenesis GO:0009405 13 10 0,000 0,03464892 0,07733331 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03464892 0,07726163 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03464892 0,0771901 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03464892 0,07711869 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03464892 0,07704742 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03464892 0,07697627 ! endoderm development GO:0007492 16 10 0,000 0,03464892 0,07690526 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03464892 0,07683438 ! arginine catabolic process GO:0006527 13 10 0,000 0,03464892 0,07676363 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03464892 0,07669301 ! proline metabolic process GO:0006560 13 10 0,000 0,03464892 0,07662252 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03464892 0,07655216 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03464892 0,07648193 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03464892 0,07641183 ! V(D)J recombination GO:0033151 28 10 0,000 0,03464892 0,07634185 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03464892 0,07627201 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03464892 0,07620229 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03464892 0,0761327 ! B cell proliferation GO:0042100 18 10 0,000 0,03464892 0,07606323 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03464892 0,0759939 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03464892 0,07592468 ! multicellular organism growth GO:0035264 18 10 0,000 0,03464892 0,0758556 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03464892 0,07578664 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03464892 0,07571781 ! epithelial cell development GO:0002064 20 10 0,000 0,03464892 0,0756491 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03464892 0,07558051 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03464892 0,07551205 ! macroautophagy GO:0016236 17 10 0,000 0,03464892 0,07544371 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03464892 0,0753755 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03464892 0,07530741 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03464892 0,07523944 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03464892 0,0751716 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03464892 0,07510388 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03464892 0,07503628 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03464892 0,0749688 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03464892 0,07490144 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03464892 0,0748342 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03464892 0,07476709 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03464892 0,07470009 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03464892 0,07463322 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03464892 0,07456646 ! response to dsRNA GO:0043331 20 10 0,000 0,03464892 0,07449982 ! DNA ligation GO:0006266 19 10 0,000 0,03464892 0,07443331 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03464892 0,07436691 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03464892 0,07430063 ! melanosome localization GO:0032400 16 10 0,000 0,03464892 0,07423446 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03464892 0,07416842 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03464892 0,07410249 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03464892 0,07403668 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03464892 0,07397099 ! mRNA cleavage GO:0006379 17 10 0,000 0,03464892 0,07390541 ! protein sumoylation GO:0016925 15 10 0,000 0,03464892 0,07383995 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03464892 0,0737746 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03464892 0,07370938 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03464892 0,07364426 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03464892 0,07357926 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03464892 0,07351438 ! salivary gland development GO:0007431 27 10 0,000 0,03464892 0,07344961 ! prophase GO:0051324 15 10 0,000 0,03464892 0,07338495 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03464892 0,07332041 ! apical protein localization GO:0045176 15 10 0,000 0,03464892 0,07325598 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03464892 0,07319166 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03464892 0,07312746 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03464892 0,07306337 ! midbrain development GO:0030901 13 10 0,000 0,03464892 0,07299939 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03464892 0,07293552 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03464892 0,07287177 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03464892 0,07280813 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03464892 0,07274459 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03464892 0,07268117 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03464892 0,07261786 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03464892 0,07255466 ! detection of calcium ion GO:0005513 23 10 0,000 0,03464892 0,07249157 ! oocyte development GO:0048599 17 10 0,000 0,03464892 0,07242859 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03464892 0,07236571 ! blastocyst formation GO:0001825 17 10 0,000 0,03464892 0,07230295 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03464892 0,0722403 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03464892 0,07217775 ! activation of innate immune response GO:0002218 12 10 0,000 0,03464892 0,07211531 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03464892 0,07205298 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03464892 0,07199076 ! response to nicotine GO:0035094 20 10 0,000 0,03464892 0,07192865 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03464892 0,07186664 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03464892 0,07180474 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03464892 0,07174295 ! negative regulation of growth GO:0045926 155 84 1,000 0,03548309 0,07340698 ! mitochondrion organization GO:0007005 148 86 1,000 0,037036 0,0765538 ! protein localization in nucleus GO:0034504 176 87 1,000 0,03782214 0,07811166 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03804771 0,0785101 ! respiratory burst GO:0045730 17 11 0,000 0,03804771 0,07844283 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03804771 0,07837567 ! neuron fate specification GO:0048665 17 11 0,000 0,03804771 0,07830862 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03804771 0,07824169 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03804771 0,07817488 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,03804771 0,07810817 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03804771 0,07804159 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03804771 0,07797511 ! response to pain GO:0048265 24 11 0,000 0,03804771 0,07790875 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03804771 0,0778425 ! T cell proliferation GO:0042098 26 11 0,000 0,03804771 0,07777636 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03804771 0,07771034 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03804771 0,07764443 ! bone resorption GO:0045453 16 11 0,000 0,03804771 0,07757863 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,03804771 0,07751294 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03804771 0,07744736 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03804771 0,07738189 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03804771 0,07731654 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03804771 0,07725129 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03804771 0,07718615 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03804771 0,07712113 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03804771 0,07705621 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03804771 0,0769914 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03804771 0,07692671 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03804771 0,07686212 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03804771 0,07679763 ! UV protection GO:0009650 19 11 0,000 0,03804771 0,07673326 ! adult heart development GO:0007512 14 11 0,000 0,03804771 0,07666899 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03804771 0,07660484 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03804771 0,07654079 ! temperature homeostasis GO:0001659 17 11 0,000 0,03804771 0,07647684 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03804771 0,076413 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03804771 0,07634927 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03804771 0,07628565 ! regulation of organ growth GO:0046620 13 11 0,000 0,03804771 0,07622213 ! pigment granule localization GO:0051875 20 11 0,000 0,03804771 0,07615872 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03804771 0,07609541 ! vasoconstriction GO:0042310 18 11 0,000 0,03804771 0,07603221 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03804771 0,07596911 ! embryonic axis specification GO:0000578 18 11 0,000 0,03804771 0,07590612 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03804771 0,07584323 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03804771 0,07578045 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03804771 0,07571777 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03804771 0,07565519 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03804771 0,07559272 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03804771 0,07553035 ! zymogen activation GO:0031638 15 11 0,000 0,03804771 0,07546808 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03804771 0,07540591 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03804771 0,07534385 ! nucleosome positioning GO:0016584 15 11 0,000 0,03804771 0,07528189 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03804771 0,07522003 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03804771 0,07515828 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03804771 0,07509662 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03804771 0,07503507 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03804771 0,07497361 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03804771 0,07491226 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03804771 0,07485101 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03804771 0,07478985 ! oocyte differentiation GO:0009994 18 11 0,000 0,03804771 0,0747288 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03804771 0,07466785 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03804771 0,07460699 ! cholesterol efflux GO:0033344 19 11 0,000 0,03804771 0,07454624 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03804771 0,07448558 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03804771 0,07442502 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03804771 0,07436457 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03804771 0,0743042 ! embryonic gut development GO:0048566 15 11 0,000 0,03804771 0,07424394 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03804771 0,07418378 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03804771 0,07412371 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03804771 0,07406374 ! defense response to fungus GO:0050832 13 11 0,000 0,03804771 0,07400386 ! developmental induction GO:0031128 19 11 0,000 0,03804771 0,07394409 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03804771 0,07388441 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03804771 0,07382482 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03804771 0,07376533 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03804771 0,07370594 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03804771 0,07364664 ! nucleus localization GO:0051647 19 11 0,000 0,03804771 0,07358744 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03804771 0,07352834 ! regulation of DNA binding GO:0051101 155 88 1,000 0,03861468 0,07456413 ! ossification GO:0001503 188 90 1,000 0,04021868 0,07759916 ! bone development GO:0060348 189 91 1,000 0,04103005 0,07910121 ! sterol metabolic process GO:0016125 152 91 1,000 0,04103005 0,07903788 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04143464 0,07975339 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04143464 0,07968964 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04143464 0,07962599 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04143464 0,07956244 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04143464 0,07949899 ! cartilage condensation GO:0001502 20 12 0,000 0,04143464 0,07943565 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04143464 0,0793724 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04143464 0,07930926 ! protein complex disassembly GO:0043241 27 12 0,000 0,04143464 0,07924621 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04143464 0,07918327 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,04143464 0,07912043 ! hippocampus development GO:0021766 26 12 0,000 0,04143464 0,07905768 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04143464 0,07899504 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04143464 0,07893249 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04143464 0,07887004 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04143464 0,0788077 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04143464 0,07874545 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04143464 0,0786833 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04143464 0,07862124 ! drug transport GO:0015893 16 12 0,000 0,04143464 0,07855929 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04143464 0,07849743 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04143464 0,07843567 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04143464 0,07837401 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04143464 0,07831244 ! focal adhesion formation GO:0048041 35 12 0,000 0,04143464 0,07825097 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04143464 0,0781896 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04143464 0,07812832 ! forebrain cell migration GO:0021885 21 12 0,000 0,04143464 0,07806714 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04143464 0,07800605 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04143464 0,07794506 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04143464 0,07788417 ! entry into host cell GO:0030260 32 12 0,000 0,04143464 0,07782337 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,04143464 0,07776266 ! monoamine transport GO:0015844 18 12 0,000 0,04143464 0,07770205 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04143464 0,07764154 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04143464 0,07758112 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04143464 0,07752079 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04143464 0,07746056 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04143464 0,07740042 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04143464 0,07734037 ! protein homotetramerization GO:0051289 21 12 0,000 0,04143464 0,07728042 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04143464 0,07722055 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04143464 0,07716079 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04143464 0,07710111 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04143464 0,07704153 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04143464 0,07698204 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04143464 0,07692264 ! cranial nerve development GO:0021545 20 12 0,000 0,04143464 0,07686333 ! fucose catabolic process GO:0019317 22 12 0,000 0,04143464 0,07680411 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04143464 0,07674498 ! histone acetylation GO:0016573 26 12 0,000 0,04143464 0,07668595 ! histone methylation GO:0016571 26 12 0,000 0,04143464 0,07662701 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04143464 0,07656815 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04143464 0,07650939 ! gland morphogenesis GO:0022612 29 12 0,000 0,04143464 0,07645072 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,04143464 0,07639213 ! T cell homeostasis GO:0043029 25 12 0,000 0,04143464 0,07633364 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04143464 0,07627524 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04143464 0,07621692 ! spleen development GO:0048536 22 12 0,000 0,04143464 0,0761587 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04143464 0,07610056 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04143464 0,07604251 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04143464 0,07598455 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04143464 0,07592668 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04143464 0,0758689 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04143464 0,07581121 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04143464 0,0757536 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04143464 0,07569608 ! response to cold GO:0009409 17 12 0,000 0,04143464 0,07563865 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04143464 0,0755813 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04143464 0,07552404 ! vitamin metabolic process GO:0006766 139 92 1,000 0,0418476 0,07621901 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,04433674 0,08069153 ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04480975 0,08149076 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04480975 0,08142921 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04480975 0,08136775 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04480975 0,08130639 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04480975 0,08124512 ! lipid localization GO:0010876 28 13 0,000 0,04480975 0,08118394 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04480975 0,08112285 ! organelle fusion GO:0048284 32 13 0,000 0,04480975 0,08106186 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04480975 0,08100095 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04480975 0,08094014 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04480975 0,08087942 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04480975 0,08081879 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04480975 0,08075825 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04480975 0,08069781 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04480975 0,08063745 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04480975 0,08057718 ! methionine metabolic process GO:0006555 27 13 0,000 0,04480975 0,080517 ! plasma membrane organization GO:0007009 24 13 0,000 0,04480975 0,08045692 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04480975 0,08039692 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04480975 0,08033701 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04480975 0,08027719 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04480975 0,08021746 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04480975 0,08015782 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04480975 0,08009827 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04480975 0,0800388 ! exocrine system development GO:0035272 32 13 0,000 0,04480975 0,07997943 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04480975 0,07992014 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04480975 0,07986094 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04480975 0,07980183 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04480975 0,0797428 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04480975 0,07968387 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04480975 0,07962501 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04480975 0,07956625 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04480975 0,07950757 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04480975 0,07944898 ! ribosome assembly GO:0042255 17 13 0,000 0,04480975 0,07939048 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04480975 0,07933206 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04480975 0,07927373 ! chromatin silencing GO:0006342 26 13 0,000 0,04480975 0,07921548 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04480975 0,07915732 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04480975 0,07909924 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04480975 0,07904125 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04480975 0,07898335 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04480975 0,07892553 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04480975 0,07886779 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04480975 0,07881014 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04480975 0,07875257 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04480975 0,07869509 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04480975 0,07863769 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04480975 0,07858037 ! embryonic placenta development GO:0001892 23 13 0,000 0,04480975 0,07852314 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04480975 0,07846599 ! insulin secretion GO:0030073 23 13 0,000 0,04480975 0,07840892 ! actin filament polymerization GO:0030041 24 13 0,000 0,04480975 0,07835194 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04480975 0,07829504 ! acrosome reaction GO:0007340 18 13 0,000 0,04480975 0,07823822 ! leukocyte differentiation GO:0002521 202 96 1,000 0,04517846 0,07882478 ! interphase GO:0051325 213 98 1,000 0,04687958 0,08173353 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,04773888 0,08317144 ! rRNA transcription GO:0009303 25 14 0,000 0,0481731 0,08386721 ! lactation GO:0007595 26 14 0,000 0,0481731 0,08380657 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,0481731 0,08374601 ! reproductive cellular process GO:0048610 20 14 0,000 0,0481731 0,08368554 ! tRNA modification GO:0006400 20 14 0,000 0,0481731 0,08362517 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0481731 0,08356487 ! regulation of S phase GO:0033261 23 14 0,000 0,0481731 0,08350467 ! water transport GO:0006833 21 14 0,000 0,0481731 0,08344455 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0481731 0,08338452 ! non-recombinational repair GO:0000726 25 14 0,000 0,0481731 0,08332457 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0481731 0,08326471 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0481731 0,08320494 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0481731 0,08314525 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0481731 0,08308565 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0481731 0,08302613 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0481731 0,0829667 ! palate development GO:0060021 31 14 0,000 0,0481731 0,08290735 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0481731 0,08284809 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0481731 0,08278891 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0481731 0,08272982 ! arginine metabolic process GO:0006525 17 14 0,000 0,0481731 0,08267081 ! regulation of heart rate GO:0002027 24 14 0,000 0,0481731 0,08261189 ! organic alcohol transport GO:0015850 29 14 0,000 0,0481731 0,08255305 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0481731 0,08249429 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0481731 0,08243562 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0481731 0,08237703 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0481731 0,08231852 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0481731 0,0822601 ! L-amino acid transport GO:0015807 30 14 0,000 0,0481731 0,08220176 ! bone mineralization GO:0030282 17 14 0,000 0,0481731 0,0821435 ! stem cell development GO:0048864 43 14 0,000 0,0481731 0,08208533 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0481731 0,08202723 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0481731 0,08196922 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0481731 0,08191129 ! cerebellum development GO:0021549 21 14 0,000 0,0481731 0,08185345 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0481731 0,08179568 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0481731 0,081738 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0481731 0,08168039 ! cofactor transport GO:0051181 26 14 0,000 0,0481731 0,08162287 ! NADP metabolic process GO:0006739 24 14 0,000 0,0481731 0,08156543 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0481731 0,08150807 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0481731 0,08145079 ! intestinal absorption GO:0050892 25 14 0,000 0,0481731 0,0813936 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0481731 0,08133648 ! oxygen transport GO:0015671 21 14 0,000 0,0481731 0,08127944 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0481731 0,08122248 ! male genitalia development GO:0030539 24 14 0,000 0,0481731 0,0811656 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0481731 0,0811088 ! regulation of axon extension GO:0030516 37 14 0,000 0,0481731 0,08105208 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0481731 0,08099544 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05152472 0,08657016 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05152472 0,08650974 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05152472 0,08644942 ! superoxide anion generation GO:0042554 20 15 0,000 0,05152472 0,08638917 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,05152472 0,08632901 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05152472 0,08626894 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05152472 0,08620895 ! copper ion transport GO:0006825 20 15 0,000 0,05152472 0,08614904 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05152472 0,08608921 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05152472 0,08602947 ! sulfate transport GO:0008272 23 15 0,000 0,05152472 0,08596981 ! response to cAMP GO:0051591 22 15 0,000 0,05152472 0,08591023 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05152472 0,08585074 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05152472 0,08579132 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05152472 0,08573199 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05152472 0,08567275 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05152472 0,08561358 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05152472 0,0855545 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05152472 0,08549549 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05152472 0,08543657 ! pituitary gland development GO:0021983 29 15 0,000 0,05152472 0,08537773 ! vesicle coating GO:0006901 33 15 0,000 0,05152472 0,08531897 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05152472 0,08526029 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05152472 0,08520169 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05152472 0,08514318 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05152472 0,08508474 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05152472 0,08502638 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05152472 0,0849681 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05152472 0,08490991 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05152472 0,08485179 ! histone deacetylation GO:0016575 20 15 0,000 0,05152472 0,08479375 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05152472 0,08473579 ! tissue regeneration GO:0042246 26 15 0,000 0,05152472 0,08467791 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05152472 0,08462011 ! water homeostasis GO:0030104 27 15 0,000 0,05152472 0,08456239 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05152472 0,08450475 ! muscle maintenance GO:0046716 26 15 0,000 0,05152472 0,08444718 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05152472 0,0843897 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05152472 0,08433229 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05152472 0,08427496 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05152472 0,08421771 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05152472 0,08416053 ! cell killing GO:0001906 29 15 0,000 0,05152472 0,08410344 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05152472 0,08404642 ! detection of bacterium GO:0016045 18 15 0,000 0,05152472 0,08398947 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05152472 0,08393261 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05152472 0,08387582 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05152472 0,08381911 ! peptide hormone processing GO:0016486 23 15 0,000 0,05152472 0,08376248 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05486464 0,08913188 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,05486464 0,08907174 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05486464 0,08901168 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05486464 0,0889517 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05486464 0,0888918 ! bone remodeling GO:0046849 27 16 0,000 0,05486464 0,08883198 ! filopodium assembly GO:0046847 32 16 0,000 0,05486464 0,08877224 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05486464 0,08871258 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05486464 0,088653 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05486464 0,0885935 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05486464 0,08853408 ! startle response GO:0001964 28 16 0,000 0,05486464 0,08847475 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05486464 0,08841549 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05486464 0,08835631 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05486464 0,0882972 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05486464 0,08823818 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05486464 0,08817924 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05486464 0,08812037 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05486464 0,08806159 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05486464 0,08800288 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05486464 0,08794425 ! response to osmotic stress GO:0006970 25 16 0,000 0,05486464 0,0878857 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,05486464 0,08782723 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,05486464 0,08776883 ! fructose metabolic process GO:0006000 25 16 0,000 0,05486464 0,08771051 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05486464 0,08765227 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05486464 0,08759411 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05486464 0,08753602 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05486464 0,08747801 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05486464 0,08742008 ! axon cargo transport GO:0008088 43 16 0,000 0,05486464 0,08736222 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05486464 0,08730444 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05486464 0,08724674 ! DNA replication initiation GO:0006270 27 16 0,000 0,05486464 0,08718912 ! neuron recognition GO:0008038 35 16 0,000 0,05486464 0,08713156 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05486464 0,08707409 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05486464 0,08701669 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05486464 0,08695937 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05486464 0,08690212 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,05486464 0,08684495 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05486464 0,08678785 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05486464 0,08673083 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05486464 0,08667388 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05486464 0,08661701 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05486464 0,08656021 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05486464 0,08650349 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,05486464 0,08644684 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,05486464 0,08639026 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05819291 0,09157106 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05819291 0,09151121 ! metencephalon development GO:0022037 30 17 0,000 0,05819291 0,09145143 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05819291 0,09139174 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05819291 0,09133212 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05819291 0,09127259 ! signal complex assembly GO:0007172 41 17 0,000 0,05819291 0,09121312 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05819291 0,09115374 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05819291 0,09109443 ! glial cell development GO:0021782 27 17 0,000 0,05819291 0,09103521 ! limbic system development GO:0021761 36 17 0,000 0,05819291 0,09097605 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05819291 0,09091698 ! adult walking behavior GO:0007628 33 17 0,000 0,05819291 0,09085798 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05819291 0,09079906 ! heart looping GO:0001947 30 17 0,000 0,05819291 0,09074021 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05819291 0,09068144 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05819291 0,09062275 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05819291 0,09056413 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05819291 0,09050559 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05819291 0,09044712 ! glycine metabolic process GO:0006544 28 17 0,000 0,05819291 0,09038873 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05819291 0,09033042 ! NAD metabolic process GO:0019674 29 17 0,000 0,05819291 0,09027218 ! membrane budding GO:0006900 37 17 0,000 0,05819291 0,09021401 ! DNA integration GO:0015074 29 17 0,000 0,05819291 0,09015592 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05819291 0,09009791 ! regulation of protein binding GO:0043393 33 17 0,000 0,05819291 0,09003996 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05819291 0,0899821 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05819291 0,08992431 ! genitalia development GO:0048806 30 17 0,000 0,05819291 0,08986659 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05819291 0,08980895 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05819291 0,08975138 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05819291 0,08969388 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05819291 0,08963646 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05819291 0,08957911 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05819291 0,08952183 ! steroid catabolic process GO:0006706 31 17 0,000 0,05819291 0,08946463 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05819291 0,0894075 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05819291 0,08935044 ! gas transport GO:0015669 25 17 0,000 0,05819291 0,08929346 ! organic cation transport GO:0015695 31 17 0,000 0,05819291 0,08923655 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05819291 0,08917971 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05819291 0,08912294 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05819291 0,08906625 ! microspike assembly GO:0030035 36 17 0,000 0,05819291 0,08900963 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05819291 0,08895308 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05819291 0,0888966 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06150957 0,09390358 ! neuron maturation GO:0042551 42 18 0,000 0,06150957 0,09384403 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06150957 0,09378456 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06150957 0,09372517 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06150957 0,09366585 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06150957 0,0936066 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06150957 0,09354743 ! memory GO:0007613 31 18 0,000 0,06150957 0,09348834 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06150957 0,09342932 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06150957 0,09337037 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06150957 0,0933115 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06150957 0,0932527 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06150957 0,09319398 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06150957 0,09313533 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06150957 0,09307675 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06150957 0,09301825 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,06150957 0,09295982 ! response to fungus GO:0009620 21 18 0,000 0,06150957 0,09290147 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06150957 0,09284318 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06150957 0,09278498 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06150957 0,09272684 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06150957 0,09266878 ! vitamin transport GO:0051180 27 18 0,000 0,06150957 0,09261079 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06150957 0,09255287 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06150957 0,09249502 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06150957 0,09243725 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06150957 0,09237955 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06150957 0,09232192 ! nerve development GO:0021675 28 18 0,000 0,06150957 0,09226436 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06150957 0,09220688 ! protein secretion GO:0009306 39 19 0,000 0,06481467 0,09710093 ! positive regulation of translation GO:0045727 30 19 0,000 0,06481467 0,0970405 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06481467 0,09698016 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,06481467 0,09691988 ! skin development GO:0043588 36 19 0,000 0,06481467 0,09685968 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,06481467 0,09679956 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06481467 0,09673951 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,06481467 0,09667953 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06481467 0,09661963 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06481467 0,09655981 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06481467 0,09650006 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,06481467 0,09644038 ! cerebral cortex development GO:0021987 36 19 0,000 0,06481467 0,09638077 ! pigmentation during development GO:0048066 41 19 0,000 0,06481467 0,09632124 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,06481467 0,09626178 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,06481467 0,0962024 ! actin filament bundle formation GO:0051017 42 19 0,000 0,06481467 0,09614309 ! neuromuscular junction development GO:0007528 34 19 0,000 0,06481467 0,09608385 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,06481467 0,09602469 ! plasma membrane fusion GO:0045026 28 19 0,000 0,06481467 0,09596559 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,06481467 0,09590657 ! peptide cross-linking GO:0018149 37 19 0,000 0,06481467 0,09584763 ! protein export from nucleus GO:0006611 36 19 0,000 0,06481467 0,09578875 ! heart process GO:0003015 30 19 0,000 0,06481467 0,09572995 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06481467 0,09567122 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,06481467 0,09561256 ! visual learning GO:0008542 36 19 0,000 0,06481467 0,09555398 ! cellular pigmentation GO:0033059 36 19 0,000 0,06481467 0,09549546 ! G1 phase GO:0051318 40 19 0,000 0,06481467 0,09543702 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,06481467 0,09537865 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06481467 0,09532035 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,06481467 0,09526212 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06481467 0,09520396 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06481467 0,09514588 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,06481467 0,09508786 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06481467 0,09502991 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,06481467 0,09497204 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06481467 0,09491424 ! cilium assembly GO:0042384 37 19 0,000 0,06481467 0,0948565 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06481467 0,09479884 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06810823 0,09955553 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06810823 0,09949508 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06810823 0,09943471 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06810823 0,09937441 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06810823 0,09931418 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,06810823 0,09925403 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06810823 0,09919395 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06810823 0,09913394 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06810823 0,099074 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06810823 0,09901414 ! response to alkaloid GO:0043279 38 20 0,000 0,06810823 0,09895435 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06810823 0,09889463 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06810823 0,09883498 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06810823 0,09877541 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06810823 0,0987159 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06810823 0,09865647 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06810823 0,09859711 ! body fluid secretion GO:0007589 31 20 0,000 0,06810823 0,09853782 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06810823 0,09847861 ! peptide secretion GO:0002790 35 20 0,000 0,06810823 0,09841946 ! stem cell differentiation GO:0048863 53 20 0,000 0,06810823 0,09836038 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06810823 0,09830138 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06810823 0,09824245 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06810823 0,09818358 ! sensory perception of pain GO:0019233 30 20 0,000 0,06810823 0,09812479 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06810823 0,09806607 ! diencephalon development GO:0021536 34 20 0,000 0,06810823 0,09800742 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06810823 0,09794883 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06810823 0,09789032 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06810823 0,09783188 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06810823 0,09777351 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06810823 0,09771521 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06810823 0,09765697 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06810823 0,09759881 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06810823 0,09754071 ! regulation of glucose import GO:0046324 29 20 0,000 0,06810823 0,09748269 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06810823 0,09742473 ! actin filament-based movement GO:0030048 43 20 0,000 0,06810823 0,09736685 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06810823 0,09730903 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,06810823 0,09725128 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06810823 0,09719359 ! negative regulation of translation GO:0017148 29 20 0,000 0,06810823 0,09713598 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06810823 0,09707844 ! regulation of cell killing GO:0031341 42 21 0,000 0,0713903 0,10169631 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,0713903 0,10163613 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,0713903 0,10157603 ! hormone secretion GO:0046879 38 21 0,000 0,0713903 0,101516 ! glycerol metabolic process GO:0006071 34 21 0,000 0,0713903 0,10145603 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,0713903 0,10139614 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,0713903 0,10133632 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,0713903 0,10127657 ! axis specification GO:0009798 38 21 0,000 0,0713903 0,10121689 ! ovarian follicle development GO:0001541 35 21 0,000 0,0713903 0,10115728 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,0713903 0,10109774 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,0713903 0,10103827 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,0713903 0,10097888 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,0713903 0,10091955 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,0713903 0,10086029 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,0713903 0,1008011 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,0713903 0,10074197 ! cytolysis GO:0019835 24 21 0,000 0,0713903 0,10068292 ! vasodilation GO:0042311 39 21 0,000 0,0713903 0,10062394 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,0713903 0,10056503 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,0713903 0,10050618 ! oogenesis GO:0048477 36 21 0,000 0,0713903 0,10044741 ! DNA modification GO:0006304 34 21 0,000 0,0713903 0,1003887 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,0713903 0,10033006 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,0713903 0,10027149 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,0713903 0,10021299 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,0713903 0,10015456 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,0713903 0,10009619 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,0713903 0,1000379 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,0713903 0,09997967 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,0713903 0,0999215 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,0713903 0,09986341 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,0713903 0,09980538 ! collagen catabolic process GO:0030574 28 21 0,000 0,0713903 0,09974743 ! sperm-egg recognition GO:0035036 21 21 0,000 0,0713903 0,09968953 ! gut development GO:0048565 39 21 0,000 0,0713903 0,09963171 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,07466092 0,10413576 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07466092 0,10407542 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07466092 0,10401516 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,07466092 0,10395497 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,07466092 0,10389484 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,07466092 0,10383479 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07466092 0,1037748 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07466092 0,10371489 ! regeneration GO:0031099 41 22 0,000 0,07466092 0,10365504 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,07466092 0,10359526 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07466092 0,10353555 ! sensory perception of taste GO:0050909 28 22 0,000 0,07466092 0,10347591 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07466092 0,10341634 ! vacuolar transport GO:0007034 36 22 0,000 0,07466092 0,10335684 ! lysosome organization GO:0007040 41 22 0,000 0,07466092 0,1032974 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07466092 0,10323804 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,07466092 0,10317874 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,07466092 0,10311951 ! fucose metabolic process GO:0006004 39 22 0,000 0,07466092 0,10306035 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07466092 0,10300125 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,07466092 0,10294222 ! ureteric bud development GO:0001657 43 22 0,000 0,07466092 0,10288327 ! renal system process GO:0003014 41 22 0,000 0,07466092 0,10282437 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,07466092 0,10276555 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07466092 0,10270679 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07466092 0,1026481 ! sarcomere organization GO:0045214 30 22 0,000 0,07466092 0,10258948 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,07466092 0,10253093 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,07466092 0,10247244 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,07466092 0,10241401 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07466092 0,10235566 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,07466092 0,10229737 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,07466092 0,10223915 ! protein stabilization GO:0050821 39 22 0,000 0,07466092 0,10218099 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07792013 0,10658092 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,07792013 0,10652037 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,07792013 0,10645988 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07792013 0,10639946 ! gluconeogenesis GO:0006094 33 23 0,000 0,07792013 0,10633911 ! viral genome replication GO:0019079 41 23 0,000 0,07792013 0,10627882 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07792013 0,10621861 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07792013 0,10615846 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07792013 0,10609838 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07792013 0,10603837 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07792013 0,10597843 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07792013 0,10591856 ! visual behavior GO:0007632 42 23 0,000 0,07792013 0,10585875 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07792013 0,10579901 ! response to ethanol GO:0045471 46 23 0,000 0,07792013 0,10573934 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07792013 0,10567973 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07792013 0,10562019 ! peroxisome organization GO:0007031 37 23 0,000 0,07792013 0,10556072 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07792013 0,10550132 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07792013 0,10544198 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07792013 0,10538271 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07792013 0,10532351 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07792013 0,10526437 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07792013 0,1052053 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07792013 0,10514629 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07792013 0,10508736 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07792013 0,10502848 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07792013 0,10496968 ! platelet activation GO:0030168 37 23 0,000 0,07792013 0,10491094 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07792013 0,10485226 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07792013 0,10479365 ! hormone transport GO:0009914 40 23 0,000 0,07792013 0,10473511 ! cell-cell recognition GO:0009988 25 23 0,000 0,07792013 0,10467663 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07792013 0,10461822 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07792013 0,10455987 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,07792013 0,10450158 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07792013 0,10444337 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07792013 0,10438521 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,08116797 0,10867565 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,08116797 0,10861521 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,08116797 0,10855483 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,08116797 0,10849452 ! vesicle docking GO:0048278 47 24 0,000 0,08116797 0,10843428 ! spinal cord development GO:0021510 47 24 0,000 0,08116797 0,10837411 ! vacuole organization GO:0007033 43 24 0,000 0,08116797 0,108314 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,08116797 0,10825396 ! digestive system process GO:0022600 39 24 0,000 0,08116797 0,10819399 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,08116797 0,10813408 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,08116797 0,10807424 ! regulation of behavior GO:0050795 43 24 0,000 0,08116797 0,10801446 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,08116797 0,10795475 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,08116797 0,10789511 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,08116797 0,10783553 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,08116797 0,10777602 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,08116797 0,10771657 ! membrane depolarization GO:0051899 39 24 0,000 0,08116797 0,10765719 ! pallium development GO:0021543 49 24 0,000 0,08116797 0,10759788 ! pentose metabolic process GO:0019321 35 24 0,000 0,08116797 0,10753863 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,08116797 0,10747944 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,08116797 0,10742032 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,08116797 0,10736127 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,08116797 0,10730228 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,08116797 0,10724335 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,08116797 0,10718449 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,08116797 0,1071257 ! regulation of amine transport GO:0051952 40 24 0,000 0,08116797 0,10706696 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,08440448 0,11127517 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,08440448 0,11121423 ! myelination GO:0042552 45 25 0,000 0,08440448 0,11115335 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,08440448 0,11109255 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,08440448 0,11103181 ! phototransduction GO:0007602 33 25 0,000 0,08440448 0,11097114 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,08440448 0,11091053 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,08440448 0,11084999 ! sperm motility GO:0030317 31 25 0,000 0,08440448 0,11078951 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,08440448 0,1107291 ! receptor metabolic process GO:0043112 46 25 0,000 0,08440448 0,11066876 ! chromosome condensation GO:0030261 45 25 0,000 0,08440448 0,11060848 ! osteoblast differentiation GO:0001649 60 25 0,000 0,08440448 0,11054827 ! neural crest cell development GO:0014032 54 25 0,000 0,08440448 0,11048813 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,08440448 0,11042805 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,08440448 0,11036803 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,08440448 0,11030808 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,08440448 0,1102482 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,08440448 0,11018838 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,08440448 0,11012862 ! immunoglobulin production GO:0002377 55 25 0,000 0,08440448 0,11006893 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,08440448 0,11000931 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,08440448 0,10994974 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,08440448 0,10989025 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,08440448 0,10983082 ! telomere organization GO:0032200 43 25 0,000 0,08440448 0,10977145 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,08440448 0,10971214 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,08440448 0,1096529 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,08762969 0,11378146 ! embryonic pattern specification GO:0009880 44 26 0,000 0,08762969 0,11372009 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,08762969 0,11365878 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,08762969 0,11359754 ! initiation of viral infection GO:0019059 57 26 0,000 0,08762969 0,11353637 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,08762969 0,11347526 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,08762969 0,11341422 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,08762969 0,11335325 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,08762969 0,11329234 ! molting cycle process GO:0022404 50 26 0,000 0,08762969 0,11323149 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,08762969 0,11317072 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,08762969 0,11311 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,08762969 0,11304935 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,08762969 0,11298877 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,08762969 0,11292825 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,08762969 0,1128678 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,08762969 0,11280741 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,08762969 0,11274708 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,08762969 0,11268682 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,08762969 0,11262663 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,08762969 0,11256649 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,08762969 0,11250643 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,08762969 0,11244642 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,08762969 0,11238648 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,08762969 0,11232661 ! blastocyst development GO:0001824 49 26 0,000 0,08762969 0,1122668 ! leukocyte proliferation GO:0070661 52 26 0,000 0,08762969 0,11220705 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,08762969 0,11214736 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,08762969 0,11208774 ! neuron fate commitment GO:0048663 48 27 0,000 0,09084365 0,116137 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,09084365 0,11607532 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,09084365 0,11601371 ! iron ion transport GO:0006826 59 27 0,000 0,09084365 0,11595216 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,09084365 0,11589068 ! protein amino acid acylation GO:0043543 55 27 0,000 0,09084365 0,11582927 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,09084365 0,11576792 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,09084365 0,11570663 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,09084365 0,11564541 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,09084365 0,11558426 ! autophagy GO:0006914 41 27 0,000 0,09084365 0,11552317 ! male gonad development GO:0008584 44 27 0,000 0,09084365 0,11546214 ! response to toxin GO:0009636 47 27 0,000 0,09084365 0,11540118 ! primary neural tube formation GO:0014020 51 27 0,000 0,09084365 0,11534028 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,09084365 0,11527945 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,09084365 0,11521868 ! glutathione metabolic process GO:0006749 39 27 0,000 0,09084365 0,11515797 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,09084365 0,11509733 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,09084365 0,11503675 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,09084365 0,11497624 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,09084365 0,11491579 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,0940464 0,11890469 ! circadian rhythm GO:0007623 50 28 0,000 0,0940464 0,11884224 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,0940464 0,11877986 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,0940464 0,11871754 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,0940464 0,11865529 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,0940464 0,1185931 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,0940464 0,11853097 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,0940464 0,11846892 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,0940464 0,11840692 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,0940464 0,118345 ! synaptogenesis GO:0007416 42 28 0,000 0,0940464 0,11828313 ! lipid oxidation GO:0034440 43 28 0,000 0,0940464 0,11822133 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,0940464 0,1181596 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,0940464 0,11809793 ! translational initiation GO:0006413 65 29 0,000 0,09723796 0,12204202 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,09723796 0,12197839 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,09723796 0,12191482 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,09723796 0,12185132 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,09723796 0,12178789 ! catechol metabolic process GO:0009712 54 29 0,000 0,09723796 0,12172453 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,09723796 0,12166123 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,09723796 0,121598 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,09723796 0,12153483 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,09723796 0,12147173 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,09723796 0,12140869 ! cell fate determination GO:0001709 60 29 0,000 0,09723796 0,12134572 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,09723796 0,12128281 ! detection of light stimulus GO:0009583 38 29 0,000 0,09723796 0,12121997 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,09723796 0,12115719 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,09723796 0,12109448 ! regulation of coagulation GO:0050818 46 29 0,000 0,09723796 0,12103184 ! phenol metabolic process GO:0018958 55 30 0,000 0,10041839 0,12492588 ! zinc ion transport GO:0006829 45 30 0,000 0,10041839 0,12486132 ! membrane docking GO:0022406 61 30 0,000 0,10041839 0,12479683 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,10041839 0,1247324 ! cell junction assembly GO:0034329 78 30 0,000 0,10041839 0,12466804 ! regulation of innate immune response GO:0045088 51 30 0,000 0,10041839 0,12460374 ! acute-phase response GO:0006953 49 30 0,000 0,10041839 0,12453951 ! myofibril assembly GO:0030239 47 30 0,000 0,10041839 0,12447535 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,10041839 0,12441126 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,10041839 0,12434722 ! phospholipid transport GO:0015914 51 30 0,000 0,10041839 0,12428326 ! ensheathment of neurons GO:0007272 57 30 0,000 0,10041839 0,12421936 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,10041839 0,12415553 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,10041839 0,12409176 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,10041839 0,12402806 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,10041839 0,12396442 ! eye morphogenesis GO:0048592 60 30 0,000 0,10041839 0,12390085 ! regulation of B cell activation GO:0050864 50 30 0,000 0,10041839 0,12383734 ! response to heat GO:0009408 50 30 0,000 0,10041839 0,1237739 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,10358773 0,12761499 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,10358773 0,12754968 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,10358773 0,12748443 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,10358773 0,12741926 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,10358773 0,12735415 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,10358773 0,1272891 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,10358773 0,12722413 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,10358773 0,12715922 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,10358773 0,12709437 ! ovulation cycle process GO:0022602 49 31 0,000 0,10358773 0,1270296 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,10358773 0,12696488 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,10358773 0,12690024 ! peptide transport GO:0015833 55 31 0,000 0,10358773 0,12683566 ! iron ion homeostasis GO:0055072 54 31 0,000 0,10358773 0,12677114 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,10358773 0,12670669 ! mesoderm formation GO:0001707 69 31 0,000 0,10358773 0,12664231 ! natural killer cell activation GO:0030101 45 31 0,000 0,10358773 0,12657799 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,10358773 0,12651374 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,10358773 0,12644955 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,10358773 0,12638543 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,10358773 0,12632137 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,10358773 0,12625738 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,10674599 0,13004094 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,10674599 0,12997513 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,10674599 0,12990939 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,10674599 0,12984371 ! cholesterol transport GO:0030301 56 32 0,000 0,10674599 0,1297781 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,10674599 0,12971256 ! spliceosome assembly GO:0000245 67 32 0,000 0,10674599 0,12964708 ! spindle organization GO:0007051 46 32 0,000 0,10674599 0,12958167 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,10674599 0,12951632 ! metanephros development GO:0001656 74 32 0,000 0,10674599 0,12945104 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,10674599 0,12938583 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,10674599 0,12932068 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,10674599 0,12925559 ! muscle cell development GO:0055001 49 32 0,000 0,10674599 0,12919058 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,10674599 0,12912562 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,10674599 0,12906074 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,10674599 0,12899591 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,10674599 0,12893116 ! ovulation cycle GO:0042698 51 32 0,000 0,10674599 0,12886646 ! peripheral nervous system development GO:0007422 64 32 0,000 0,10674599 0,12880184 ! BMP signaling pathway GO:0030509 64 32 0,000 0,10674599 0,12873728 ! hindbrain development GO:0030902 61 32 0,000 0,10674599 0,12867278 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,10674599 0,12860834 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,10674599 0,12854398 ! gene silencing GO:0016458 65 32 0,000 0,10674599 0,12847967 ! post-embryonic development GO:0009791 69 33 0,000 0,10989324 0,13220157 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10989324 0,1321355 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10989324 0,1320695 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10989324 0,13200356 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10989324 0,13193769 ! cell fate specification GO:0001708 52 33 0,000 0,10989324 0,13187189 ! sterol transport GO:0015918 57 33 0,000 0,10989324 0,13180615 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,10989324 0,13174048 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10989324 0,13167487 ! adult locomotory behavior GO:0008344 59 33 0,000 0,10989324 0,13160933 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10989324 0,13154385 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,1130295 0,13523072 ! glial cell differentiation GO:0010001 63 34 0,000 0,1130295 0,13516351 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,1130295 0,13509637 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,1130295 0,13502929 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,1130295 0,13496228 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,1130295 0,13489533 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,1130295 0,13482845 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,1130295 0,13476164 ! mismatch repair GO:0006298 46 34 0,000 0,1130295 0,13469489 ! spermatid development GO:0007286 63 34 0,000 0,1130295 0,13462821 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,1130295 0,1345616 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,1130295 0,13449505 ! placenta development GO:0001890 53 34 0,000 0,1130295 0,13442857 ! regulation of muscle development GO:0048634 70 35 0,000 0,11615482 0,13807732 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,11615482 0,13800913 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,11615482 0,13794102 ! odontogenesis GO:0042476 66 35 0,000 0,11615482 0,13787296 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,11615482 0,13780498 ! female gonad development GO:0008585 58 35 0,000 0,11615482 0,13773706 ! telencephalon development GO:0021537 68 35 0,000 0,11615482 0,13766921 ! cytokine production GO:0001816 59 35 0,000 0,11615482 0,13760143 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,11615482 0,13753371 ! neural tube formation GO:0001841 67 35 0,000 0,11615482 0,13746606 ! vesicle localization GO:0051648 64 35 0,000 0,11615482 0,13739847 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,11926923 0,14101315 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,11926923 0,14094389 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,11926923 0,1408747 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,11926923 0,14080557 ! cell junction organization GO:0034330 86 36 0,000 0,11926923 0,14073652 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,11926923 0,14066753 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,11926923 0,14059861 ! positive regulation of cell development GO:0010720 80 36 0,000 0,11926923 0,14052975 ! regulation of proteolysis GO:0030162 72 36 0,000 0,11926923 0,14046097 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,11926923 0,14039225 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,11926923 0,1403236 ! aerobic respiration GO:0009060 55 36 0,000 0,11926923 0,14025501 ! embryonic organ development GO:0048568 57 36 0,000 0,11926923 0,1401865 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,11926923 0,14011805 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,11926923 0,14004966 ! RNA export from nucleus GO:0006405 56 37 0,000 0,12237276 0,14362384 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,12237276 0,14355381 ! meiosis I GO:0007127 65 37 0,000 0,12237276 0,14348385 ! sister chromatid segregation GO:0000819 58 37 0,000 0,12237276 0,14341396 ! actomyosin structure organization GO:0031032 62 37 0,000 0,12237276 0,14334414 ! organic anion transport GO:0015711 68 37 0,000 0,12237276 0,14327439 ! tissue remodeling GO:0048771 76 37 0,000 0,12237276 0,1432047 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,12237276 0,14313508 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,12237276 0,14306553 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,12237276 0,14299605 ! spermatid differentiation GO:0048515 66 37 0,000 0,12237276 0,14292663 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,12546547 0,14646769 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,12546547 0,14639666 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,12546547 0,1463257 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,12546547 0,1462548 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,12546547 0,14618398 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,12546547 0,14611322 ! lipid homeostasis GO:0055088 67 38 0,000 0,12546547 0,14604253 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,12546547 0,14597191 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,12546547 0,14590136 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,12546547 0,14583087 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,12546547 0,14576046 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,12546547 0,14569011 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,12546547 0,14561983 ! mRNA catabolic process GO:0006402 71 39 0,000 0,12854737 0,14912487 ! mammary gland development GO:0030879 86 39 0,000 0,12854737 0,149053 ! learning GO:0007612 77 39 0,000 0,12854737 0,1489812 ! ear morphogenesis GO:0042471 60 39 0,000 0,12854737 0,14890947 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,12854737 0,14883781 ! segmentation GO:0035282 67 39 0,000 0,12854737 0,14876622 ! ion transmembrane transport GO:0034220 66 39 0,000 0,12854737 0,1486947 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,12854737 0,14862325 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,12854737 0,14855186 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,12854737 0,14848055 ! RNA modification GO:0009451 57 39 0,000 0,12854737 0,1484093 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,12854737 0,14833812 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,13161852 0,15180928 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,13161852 0,15173654 ! feeding behavior GO:0007631 59 40 0,000 0,13161852 0,15166387 ! negative regulation of binding GO:0051100 72 40 0,000 0,13161852 0,15159127 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,13161852 0,15151874 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,13161852 0,15144627 ! maintenance of protein location GO:0045185 91 40 0,000 0,13161852 0,15137388 ! cytokinesis GO:0000910 72 40 0,000 0,13161852 0,15130156 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,13467895 0,15474572 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,13467895 0,15467186 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,13467895 0,15459806 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,13467895 0,15452434 ! gliogenesis GO:0042063 88 41 0,000 0,13467895 0,15445069 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,13467895 0,1543771 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,13467895 0,15430359 ! female gamete generation GO:0007292 61 41 0,000 0,13467895 0,15423015 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,13467895 0,15415678 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,13772869 0,15757262 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,13772869 0,15749773 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,13772869 0,15742291 ! regulation of tube size GO:0035150 71 42 0,000 0,13772869 0,15734816 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,13772869 0,15727348 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,13772869 0,15719887 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,13772869 0,15712433 ! neuron migration GO:0001764 79 42 0,000 0,13772869 0,15704987 ! regulation of protein secretion GO:0050708 71 42 0,000 0,13772869 0,15697547 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,13772869 0,15690115 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,14076778 0,1602874 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,14076778 0,16021158 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,14076778 0,16013583 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,14076778 0,16006015 ! glucose transport GO:0015758 65 43 0,000 0,14076778 0,15998454 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,14076778 0,15990901 ! neural tube development GO:0021915 77 43 0,000 0,14076778 0,15983354 ! striated muscle contraction GO:0006941 77 43 0,000 0,14076778 0,15975815 ! phagocytosis GO:0006909 90 43 0,000 0,14076778 0,15968283 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,14076778 0,15960758 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,14379626 0,16296458 ! hexose transport GO:0008645 67 44 0,000 0,14379626 0,16288786 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,14379626 0,16281121 ! biopolymer methylation GO:0043414 84 44 0,000 0,14379626 0,16273463 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,14379626 0,16265812 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,14379626 0,16258168 ! developmental growth GO:0048589 82 44 0,000 0,14379626 0,16250531 ! maintenance of location in cell GO:0051651 97 44 0,000 0,14379626 0,16242902 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,14681417 0,16576016 ! glycolysis GO:0006096 65 45 0,000 0,14681417 0,16568241 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,14681417 0,16560474 ! leukocyte migration GO:0050900 68 45 0,000 0,14681417 0,16552713 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,14681417 0,1654496 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,14681417 0,16537215 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,14681417 0,16529476 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,14681417 0,16521745 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,14681417 0,16514021 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,14681417 0,16506304 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,14681417 0,16498594 ! cell growth GO:0016049 84 45 0,000 0,14681417 0,16490892 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,14982155 0,16820842 ! pigmentation GO:0043473 100 46 0,000 0,14982155 0,16812996 ! positive regulation of defense response GO:0031349 76 47 0,000 0,15281842 0,17141311 ! response to calcium ion GO:0051592 81 47 0,000 0,15281842 0,17133323 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,15281842 0,17125343 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,15281842 0,1711737 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,15281842 0,17109405 ! JNK cascade GO:0007254 91 47 0,000 0,15281842 0,17101447 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,15281842 0,17093497 ! methylation GO:0032259 90 47 0,000 0,15281842 0,17085554 ! Notch signaling pathway GO:0007219 96 48 0,000 0,15580482 0,17411352 ! cellular component disassembly GO:0022411 86 48 0,000 0,15580482 0,17403269 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,15580482 0,17395193 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,15580482 0,17387125 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,15580482 0,17379064 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,15580482 0,17371011 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,15580482 0,17362965 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,15580482 0,17354926 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,15580482 0,17346895 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,1587808 0,17670056 ! regulation of action potential GO:0001508 95 49 0,000 0,1587808 0,17661887 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,1587808 0,17653725 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,1587808 0,17645571 ! regulation of ion transport GO:0043269 77 49 0,000 0,1587808 0,17637424 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,1587808 0,17629285 ! peptide metabolic process GO:0006518 76 49 0,000 0,1587808 0,17621154 ! response to temperature stimulus GO:0009266 76 49 0,000 0,1587808 0,1761303 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,1587808 0,17604913 ! endocrine system development GO:0035270 104 49 0,000 0,1587808 0,17596804 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,1587808 0,17588702 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,1587808 0,17580608 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,1587808 0,17572521 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,1587808 0,17564442 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,16174639 0,17884274 ! neuromuscular process GO:0050905 99 50 0,000 0,16174639 0,17876059 ! regulation of ossification GO:0030278 117 50 0,000 0,16174639 0,17867852 ! inner ear development GO:0048839 79 50 0,000 0,16174639 0,17859652 ! histone modification GO:0016570 91 50 0,000 0,16174639 0,17851459 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,16174639 0,17843274 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,16174639 0,17835097 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,16174639 0,17826927 ! positive regulation of binding GO:0051099 78 51 0,000 0,16470162 0,18144327 ! viral infectious cycle GO:0019058 99 51 0,000 0,16470162 0,18136023 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,16470162 0,18127726 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,16470162 0,18119437 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,16470162 0,18111156 ! excretion GO:0007588 83 51 0,000 0,16470162 0,18102882 ! chromatin remodeling GO:0006338 109 51 0,000 0,16470162 0,18094616 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,16470162 0,18086357 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,16470162 0,18078106 ! vesicle organization GO:0016050 107 51 0,000 0,16470162 0,18069863 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,16470162 0,18061627 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,16470162 0,18053398 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,16470162 0,18045177 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,16764653 0,18359469 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,16764653 0,18351117 ! membrane fusion GO:0006944 110 52 0,000 0,16764653 0,18342771 ! covalent chromatin modification GO:0016569 101 52 0,000 0,16764653 0,18334434 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,16764653 0,18326104 ! cartilage development GO:0051216 90 52 0,000 0,16764653 0,18317781 ! synapse organization GO:0050808 85 52 0,000 0,16764653 0,18309466 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,17058115 0,18621518 ! RNA catabolic process GO:0006401 93 53 0,000 0,17058115 0,18613072 ! regulation of translational initiation GO:0006446 82 53 0,000 0,17058115 0,18604635 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,17058115 0,18596205 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,17058115 0,18587783 ! cell maturation GO:0048469 100 53 0,000 0,17058115 0,18579368 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,17058115 0,18570961 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,17350553 0,18880791 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,17350553 0,18872256 ! cell recognition GO:0008037 85 54 0,000 0,17350553 0,18863728 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,17350553 0,18855207 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,17350553 0,18846695 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,17350553 0,1883819 ! chloride transport GO:0006821 90 55 0,000 0,17641969 0,19145952 ! glucose catabolic process GO:0006007 82 55 0,000 0,17641969 0,1913732 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,17641969 0,19128696 ! gastrulation GO:0007369 112 55 0,000 0,17641969 0,19120079 ! nuclear export GO:0051168 97 55 0,000 0,17641969 0,19111471 ! regulation of actin filament length GO:0030832 105 56 0,000 0,17932367 0,19417315 ! sensory perception of smell GO:0007608 80 56 0,000 0,17932367 0,19408581 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,17932367 0,19399854 ! proton transport GO:0015992 94 56 0,000 0,17932367 0,19391135 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,17932367 0,19382423 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,18221751 0,19686364 ! maintenance of location GO:0051235 118 57 0,000 0,18221751 0,19677528 ! hydrogen transport GO:0006818 97 58 0,000 0,18510124 0,19979972 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,18510124 0,19971012 ! regulation of endocytosis GO:0030100 91 58 0,000 0,18510124 0,19962061 ! adult behavior GO:0030534 99 58 0,000 0,18510124 0,19953117 ! regulation of cellular component size GO:0032535 109 59 0,000 0,1879749 0,20253811 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,1879749 0,20244745 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1879749 0,20235687 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,1879749 0,20226637 ! DNA catabolic process GO:0006308 86 59 0,000 0,1879749 0,20217595 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,1879749 0,20208561 ! establishment of organelle localization GO:0051656 109 59 0,000 0,1879749 0,20199535 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,19083851 0,20498101 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,19083851 0,20488954 ! regulation of heart contraction GO:0008016 110 60 0,000 0,19083851 0,20479816 ! camera-type eye development GO:0043010 116 60 0,000 0,19083851 0,20470685 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,19083851 0,20461563 ! kidney development GO:0001822 122 60 0,000 0,19083851 0,20452448 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,19369213 0,20749032 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,19369213 0,20739798 ! mesoderm development GO:0007498 119 61 0,000 0,19369213 0,20730572 ! tRNA processing GO:0008033 89 61 0,000 0,19369213 0,20721355 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,19369213 0,20712145 ! ear development GO:0043583 103 62 0,000 0,19653578 0,21006889 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,19653578 0,20997561 ! gonad development GO:0008406 98 62 0,000 0,19653578 0,20988241 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,19653578 0,2097893 ! regulation of mitosis GO:0007088 105 63 0,000 0,19936949 0,21271973 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,19936949 0,21262544 ! detection of external stimulus GO:0009581 91 63 0,000 0,19936949 0,21253123 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,19936949 0,21243711 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,2021933 0,21535063 ! cell redox homeostasis GO:0045454 102 64 0,000 0,2021933 0,21525534 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,2021933 0,21516014 ! single fertilization GO:0007338 75 64 0,000 0,2021933 0,21506502 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,20500725 0,21796175 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,20500725 0,21786547 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,20500725 0,21776929 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,20500725 0,21767318 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,20500725 0,21757716 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,20781136 0,22045597 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,20781136 0,22035881 ! extracellular matrix organization GO:0030198 133 66 0,000 0,20781136 0,22026173 ! secondary metabolic process GO:0019748 116 66 0,000 0,20781136 0,22016474 ! developmental maturation GO:0021700 116 66 0,000 0,20781136 0,22006784 ! cell projection assembly GO:0030031 120 66 0,000 0,20781136 0,21997102 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,21060568 0,22283081 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,21060568 0,22273286 ! lung development GO:0030324 144 67 0,000 0,21060568 0,222635 ! chromosome segregation GO:0007059 113 67 0,000 0,21060568 0,22253722 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,21060568 0,22243953 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,21060568 0,22234193 ! hexose catabolic process GO:0019320 104 67 0,000 0,21060568 0,22224441 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,21060568 0,22214698 ! adaptive immune response GO:0002250 119 67 0,000 0,21060568 0,22204963 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,21060568 0,22195237 ! amino acid transport GO:0006865 125 68 0,000 0,21339023 0,22478848 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,21339023 0,2246901 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,21339023 0,22459181 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,21339023 0,22449361 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,21339023 0,22439549 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,21616505 0,22721412 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,21616505 0,2271149 ! urogenital system development GO:0001655 137 69 0,000 0,21616505 0,22701576 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,21616505 0,22691671 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,21616505 0,22681775 ! antigen processing and presentation GO:0019882 104 69 0,000 0,21616505 0,22671888 ! appendage morphogenesis GO:0035107 135 70 0,000 0,21893018 0,22951896 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,21893018 0,22941899 ! amine catabolic process GO:0009310 117 71 0,000 0,22168564 0,23220533 ! reproductive structure development GO:0048608 113 71 0,000 0,22168564 0,23210429 ! appendage development GO:0048736 136 71 0,000 0,22168564 0,23200333 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,22168564 0,23190246 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,22168564 0,23180167 ! regulation of immune effector process GO:0002697 137 71 0,000 0,22168564 0,23170098 ! acute inflammatory response GO:0002526 113 72 0,000 0,22443147 0,23446901 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,22443147 0,23436724 ! carbohydrate transport GO:0008643 110 72 0,000 0,22443147 0,23426556 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,22443147 0,23416397 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,22443147 0,23406247 ! respiratory system development GO:0060541 153 72 0,000 0,22443147 0,23396106 ! learning or memory GO:0007611 147 73 0,000 0,22716771 0,23671092 ! regulation of blood pressure GO:0008217 125 73 0,000 0,22716771 0,23660845 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,22716771 0,23650606 ! axon guidance GO:0007411 139 73 0,000 0,22716771 0,23640377 ! fertilization GO:0009566 90 73 0,000 0,22716771 0,23630156 ! transition metal ion transport GO:0000041 126 74 0,000 0,22989439 0,23903453 ! neurotransmitter transport GO:0006836 123 74 0,000 0,22989439 0,23893127 ! meiosis GO:0007126 121 74 0,000 0,22989439 0,23882811 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,22989439 0,23872503 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,22989439 0,23862204 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,22989439 0,23851914 ! eye development GO:0001654 143 74 0,000 0,22989439 0,23841633 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,23261153 0,24113026 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,23261153 0,24102642 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,23261153 0,24092266 ! meiotic cell cycle GO:0051321 122 75 0,000 0,23261153 0,24081899 ! rhythmic process GO:0048511 128 75 0,000 0,23261153 0,24071542 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,23531918 0,2434127 ! defense response to bacterium GO:0042742 89 76 0,000 0,23531918 0,2433081 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,23531918 0,24320358 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,23531918 0,24309916 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,23801736 0,24578102 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,23801736 0,24567558 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,23801736 0,24557023 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,23801736 0,24546497 ! blood coagulation GO:0007596 146 78 0,000 0,24070612 0,2481315 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,24070612 0,24802523 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,24070612 0,24791906 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,24338547 0,25057144 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,24338547 0,25046426 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,24338547 0,25035718 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,24338547 0,25025019 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,24338547 0,25014329 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,24605546 0,25277944 ! response to metal ion GO:0010038 140 80 0,000 0,24605546 0,25267155 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,24605546 0,25256376 ! inorganic anion transport GO:0015698 138 80 0,000 0,24605546 0,25245605 ! response to hypoxia GO:0001666 171 81 0,000 0,24871612 0,25507714 ! digestion GO:0007586 112 81 0,000 0,24871612 0,25496846 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,24871612 0,25485987 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,24871612 0,25475138 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,24871612 0,25464297 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,25136747 0,25724804 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,25136747 0,25713866 ! response to oxygen levels GO:0070482 176 83 0,000 0,25400956 0,25973098 ! regulation of lyase activity GO:0051339 160 83 0,000 0,25400956 0,25962064 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,25664241 0,26220027 ! hemostasis GO:0007599 158 84 0,000 0,25664241 0,26208898 ! regulation of ligase activity GO:0051340 142 84 0,000 0,25664241 0,26197778 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,25664241 0,26186668 ! response to unfolded protein GO:0006986 131 85 0,000 0,25926605 0,26443159 ! nucleosome assembly GO:0006334 122 85 0,000 0,25926605 0,26431954 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,25926605 0,26420759 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,25926605 0,26409573 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,26188052 0,26664602 ! response to inorganic substance GO:0010035 153 86 0,000 0,26188052 0,26653322 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,26188052 0,26642052 ! chromatin assembly GO:0031497 124 86 0,000 0,26188052 0,26630792 ! tube morphogenesis GO:0035239 176 86 0,000 0,26188052 0,26619541 ! alcohol catabolic process GO:0046164 130 86 0,000 0,26188052 0,266083 ! amine transport GO:0015837 155 86 0,000 0,26188052 0,26597068 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,26448585 0,26850336 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,26448585 0,26839011 ! cellular respiration GO:0045333 135 88 0,000 0,26708207 0,2709104 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,26708207 0,27079624 ! gland development GO:0048732 206 88 0,000 0,26708207 0,27068217 ! regulation of neurological system process GO:0031644 148 88 0,000 0,26708207 0,2705682 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,26708207 0,27045432 ! cellular defense response GO:0006968 114 89 0,000 0,26966922 0,27295925 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,26966922 0,27284446 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,27224731 0,27533713 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,27224731 0,27522144 ! sex differentiation GO:0007548 145 90 0,000 0,27224731 0,27510585 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,27224731 0,27499036 ! response to protein stimulus GO:0051789 149 91 0,000 0,27481639 0,27746884 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,27481639 0,27735245 ! regulation of defense response GO:0031347 149 92 0,000 0,27737649 0,2798188 ! nucleosome organization GO:0034728 138 92 0,000 0,27737649 0,27970152 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,27737649 0,27958435 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,27992763 0,28203764 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,27992763 0,28191958 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,27992763 0,28180163 ! regulation of membrane potential GO:0042391 164 93 0,000 0,27992763 0,28168377 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,27992763 0,28156601 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,28246985 0,28400438 ! female pregnancy GO:0007565 164 94 0,000 0,28246985 0,28388574 ! regulation of T cell activation GO:0050863 158 94 0,000 0,28246985 0,28376721 ! forebrain development GO:0030900 188 95 0,000 0,28500319 0,28619268 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,28500319 0,28607329 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,28752766 0,28848688 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,28752766 0,28836663 ! positive regulation of immune response GO:0050778 156 96 0,000 0,28752766 0,28824648 ! detection of stimulus GO:0051606 151 96 0,000 0,28752766 0,28812642 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,2900433 0,2905263 ! response to virus GO:0009615 160 98 0,000 0,29255014 0,29291537 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,29255014 0,29279353 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,29255014 0,29267178 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,29504821 0,29504821