pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6592-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 5,000 7,799E-15 1,905E-11 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 5,000 5,093E-13 6,221E-10 ! positive regulation of hormone secretion GO:0046887 35 19 5,000 2,927E-11 2,384E-08 ! carbohydrate homeostasis GO:0033500 59 39 6,000 4,921E-11 3,006E-08 GO:0042593|glucose homeostasis, ! regulation of intracellular protein transport GO:0033157 86 42 6,000 8,562E-11 4,183E-08 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 6,000 1,68E-10 6,842E-08 ! regulation of insulin secretion GO:0050796 42 25 5,000 1,88E-10 6,562E-08 ! regulation of peptide secretion GO:0002791 52 29 5,000 4,99E-10 1,524E-07 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 5,561E-10 1,509E-07 ! regulation of intracellular transport GO:0032386 108 57 6,000 8,056E-10 1,968E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,664E-09 3,695E-07 ! organ growth GO:0035265 15 7 3,000 3,873E-09 7,884E-07 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 3,873E-09 7,278E-07 GO:0046676|negative regulation of insulin secretion, ! negative regulation of focal adhesion formation GO:0051895 21 7 3,000 3,873E-09 6,758E-07 ! regulation of hormone secretion GO:0046883 69 41 5,000 4,574E-09 7,449E-07 ! regulation of focal adhesion formation GO:0051893 23 8 3,000 7,726E-09 1,18E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 7,726E-09 1,11E-06 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 3,000 1,387E-08 1,883E-06 ! regulation of protein transport GO:0051223 165 87 6,000 1,642E-08 2,111E-06 GO:0070201|regulation of establishment of protein localization, ! regulation of protein kinase B signaling cascade GO:0051896 27 10 3,000 2,306E-08 2,817E-06 ! regulation of protein localization GO:0032880 188 97 6,000 3,512E-08 4,086E-06 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 3,000 3,614E-08 4,014E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of secretion GO:0051047 110 61 5,000 5,354E-08 5,686E-06 ! DNA damage checkpoint GO:0000077 78 35 4,000 1,064E-07 1,083E-05 ! cell cycle checkpoint GO:0000075 145 71 5,000 1,344E-07 1,314E-05 ! DNA integrity checkpoint GO:0031570 82 38 4,000 1,632E-07 1,533E-05 ! negative regulation of hormone secretion GO:0046888 26 17 3,000 2,567E-07 2,323E-05 ! endothelial cell migration GO:0043542 31 17 3,000 2,567E-07 2,24E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 3,000 2,567E-07 2,163E-05 ! cardiac muscle tissue development GO:0048738 34 17 3,000 2,567E-07 2,091E-05 ! cellular response to hormone stimulus GO:0032870 182 85 5,000 3,955E-07 3,116E-05 ! inositol metabolic process GO:0006020 33 19 3,000 4,16E-07 3,176E-05 ! positive regulation of MAP kinase activity GO:0043406 174 93 5,000 6,746E-07 4,994E-05 ! myoblast cell fate commitment GO:0048625 18 6 2,000 6,902E-07 4,959E-05 ! regulation of cell-matrix adhesion GO:0001952 81 23 3,000 9,407E-07 6,566E-05 GO:0010810|regulation of cell-substrate adhesion, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 1,295E-06 8,787E-05 ! lipid modification GO:0030258 112 60 4,000 1,676E-06 1,106E-04 ! ER overload response GO:0006983 13 8 2,000 1,923E-06 1,236E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 1,923E-06 1,205E-04 ! DNA damage response, signal transduction GO:0042770 136 62 4,000 1,975E-06 1,206E-04 ! negative regulation of protein kinase cascade GO:0010741 72 30 3,000 2,86E-06 1,704E-04 ! activation of MAPK activity GO:0000187 124 67 4,000 2,909E-06 1,692E-04 ! triglyceride metabolic process GO:0006641 46 33 3,000 4,238E-06 2,408E-04 ! negative regulation of secretion GO:0051048 68 35 3,000 5,395E-06 2,996E-04 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 5,626E-06 3,054E-04 ! phosphoinositide metabolic process GO:0030384 146 77 4,000 5,798E-06 3,079E-04 ! negative regulation of cell adhesion GO:0007162 94 37 3,000 6,771E-06 3,519E-04 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 7,483E-06 3,809E-04 ! neutral lipid metabolic process GO:0006638 54 38 3,000 7,548E-06 3,763E-04 GO:0006639|acylglycerol metabolic process, ! regulation of protein stability GO:0031647 77 38 3,000 7,548E-06 3,688E-04 ! glycerol ether metabolic process GO:0006662 57 40 3,000 9,298E-06 4,454E-04 ! negative regulation of transport GO:0051051 164 85 4,000 9,426E-06 4,428E-04 ! organic ether metabolic process GO:0018904 59 42 3,000 1,133E-05 5,223E-04 ! hormone-mediated signaling GO:0009755 84 43 3,000 1,246E-05 5,637E-04 ! polyol metabolic process GO:0019751 77 45 3,000 1,497E-05 6,648E-04 ! G1/S transition checkpoint GO:0031575 37 15 2,000 1,537E-05 6,703E-04 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 1,537E-05 6,586E-04 ! negative regulation of cell migration GO:0030336 122 46 3,000 1,635E-05 6,887E-04 ! myoblast differentiation GO:0045445 50 17 2,000 2,285E-05 9,463E-04 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 3,000 2,672E-05 1,088E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 2,736E-05 1,096E-03 ! regulation of multicellular organism growth GO:0040014 90 55 3,000 3,34E-05 1,316E-03 ! negative regulation of cell motion GO:0051271 142 55 3,000 3,34E-05 1,295E-03 ! RNA elongation GO:0006354 90 56 3,000 3,588E-05 1,37E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 3,804E-05 1,43E-03 ! pancreas development GO:0031016 40 20 2,000 3,804E-05 1,408E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 4,427E-05 1,614E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 5,114E-05 1,837E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 6,083E-05 2,154E-03 ! multicellular organism reproduction GO:0032504 123 65 3,000 6,465E-05 2,256E-03 GO:0048609|reproductive process in a multicellular organism, ! protein tetramerization GO:0051262 57 25 2,000 7,583E-05 2,609E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 8,551E-05 2,901E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 9,138E-05 3,058E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 9,597E-05 3,168E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,067E-04 3,477E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,067E-04 3,431E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,067E-04 3,386E-03 ! nucleobase transport GO:0015851 6 5 1,000 1,067E-04 3,343E-03 ! muscle cell proliferation GO:0033002 12 5 1,000 1,067E-04 3,301E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,067E-04 3,259E-03 ! fat cell differentiation GO:0045444 57 28 2,000 1,072E-04 3,234E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 1,193E-04 3,555E-03 ! protein oligomerization GO:0051259 149 79 3,000 1,385E-04 4,076E-03 ! muscle cell differentiation GO:0042692 178 81 3,000 1,526E-04 4,437E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 3,000 1,526E-04 4,385E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 1,598E-04 4,538E-03 ! positive regulation of catabolic process GO:0009896 72 32 2,000 1,608E-04 4,515E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 2,232E-04 6,196E-03 ! male sex determination GO:0030238 15 7 1,000 2,232E-04 6,126E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 2,232E-04 6,058E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,232E-04 5,992E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,232E-04 5,926E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 2,489E-04 6,538E-03 ! regulation of cell adhesion GO:0030155 241 92 3,000 2,492E-04 6,476E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 2,696E-04 6,933E-03 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 2,913E-04 7,414E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,969E-04 7,478E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,969E-04 7,402E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,969E-04 7,327E-03 ! cardiac muscle cell differentiation GO:0055007 31 8 1,000 2,969E-04 7,254E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 2,969E-04 7,182E-03 ! response to tumor cell GO:0002347 16 8 1,000 2,969E-04 7,112E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 2,969E-04 7,043E-03 ! transcription initiation GO:0006352 171 97 3,000 3,051E-04 7,167E-03 ! mesenchymal cell development GO:0014031 94 41 2,000 3,382E-04 7,869E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! hormone metabolic process GO:0042445 171 100 3,000 3,427E-04 7,898E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,809E-04 8,698E-03 ! Golgi to endosome transport GO:0006895 25 9 1,000 3,809E-04 8,617E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 3,809E-04 8,538E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 3,809E-04 8,461E-03 ! retinoic acid receptor signaling pathway GO:0048384 16 9 1,000 3,809E-04 8,384E-03 ! icosanoid secretion GO:0032309 15 9 1,000 3,809E-04 8,309E-03 GO:0050482|arachidonic acid secretion, ! regulation of developmental growth GO:0048638 16 10 1,000 4,752E-04 0,01027271 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 4,752E-04 0,0101826 ! protein heterooligomerization GO:0051291 17 10 1,000 4,752E-04 0,01009405 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 4,752E-04 0,01000704 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of gene-specific transcription GO:0032583 102 46 2,000 4,759E-04 9,937E-03 ! positive regulation of protein transport GO:0051222 80 46 2,000 4,759E-04 9,852E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 5,071E-04 0,01041085 ! cortical actin cytoskeleton organization GO:0030866 29 11 1,000 5,795E-04 0,01179768 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 5,795E-04 0,01170017 ! keratinocyte proliferation GO:0043616 19 11 1,000 5,795E-04 0,01160427 ! regulation of intracellular pH GO:0051453 21 11 1,000 5,795E-04 0,01150993 ! acid secretion GO:0046717 20 11 1,000 5,795E-04 0,01141711 ! cardiac cell differentiation GO:0035051 36 11 1,000 5,795E-04 0,01132577 ! regulation of embryonic development GO:0045995 35 11 1,000 5,795E-04 0,01123588 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 6,939E-04 0,0133481 ! cortical cytoskeleton organization GO:0030865 30 12 1,000 6,939E-04 0,01324382 ! virus-host interaction GO:0019048 30 12 1,000 6,939E-04 0,01314116 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 6,939E-04 0,01304007 ! localization within membrane GO:0051668 26 12 1,000 6,939E-04 0,01294053 ! response to UV GO:0009411 120 55 2,000 8,049E-04 0,01489742 ! cGMP metabolic process GO:0046068 18 13 1,000 8,183E-04 0,01503096 GO:0006182|cGMP biosynthetic process, ! response to X-ray GO:0010165 28 13 1,000 8,183E-04 0,01491879 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 8,183E-04 0,01480828 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 8,183E-04 0,0146994 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 8,183E-04 0,0145921 ! skeletal muscle fiber development GO:0048741 130 56 2,000 8,485E-04 0,01502033 ! regulation of DNA replication GO:0006275 105 56 2,000 8,485E-04 0,01491227 ! muscle fiber development GO:0048747 131 57 2,000 8,935E-04 0,01559098 ! heart morphogenesis GO:0003007 105 57 2,000 8,935E-04 0,01548041 ! positive regulation of cell migration GO:0030335 137 58 2,000 9,4E-04 0,01617113 ! regulation of cellular pH GO:0030641 27 14 1,000 9,526E-04 0,01627474 ! response to gamma radiation GO:0010332 30 14 1,000 9,526E-04 0,01616172 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 9,526E-04 0,01605026 ! regulation of mRNA processing GO:0050684 26 15 1,000 1,097E-03 0,01835313 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,097E-03 0,01822827 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,251E-03 0,02064707 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 1,251E-03 0,0205085 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 1,251E-03 0,02037177 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,251E-03 0,02023686 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 1,251E-03 0,02010858 ! positive regulation of cell motion GO:0051272 157 65 2,000 1,309E-03 0,02089384 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 1,368E-03 0,02169479 ! response to retinoic acid GO:0032526 31 18 1,000 1,588E-03 0,02502821 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 1,000 1,588E-03 0,02486777 ! long-chain fatty acid transport GO:0015909 32 18 1,000 1,588E-03 0,02470938 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,588E-03 0,02455299 ! response to vitamin A GO:0033189 32 19 1,000 1,771E-03 0,0272104 ! regulation of caspase activity GO:0043281 136 74 2,000 1,901E-03 0,02902129 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,964E-03 0,02979407 ! response to vitamin GO:0033273 36 20 1,000 1,964E-03 0,02961016 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 1,964E-03 0,0294285 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,964E-03 0,02924906 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 1,964E-03 0,02907179 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 2,000 2,051E-03 0,03019099 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 2,13E-03 0,03115249 ! cytosolic calcium ion homeostasis GO:0051480 149 77 2,000 2,13E-03 0,03096706 ! regulation of catabolic process GO:0009894 173 77 2,000 2,13E-03 0,03078382 ! lipid phosphorylation GO:0046834 43 21 1,000 2,166E-03 0,03111995 ! smooth muscle contraction GO:0006939 48 21 1,000 2,166E-03 0,03093796 ! regulation of vasoconstriction GO:0019229 40 21 1,000 2,166E-03 0,03075809 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 2,166E-03 0,0305803 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 2,166E-03 0,03040455 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 2,377E-03 0,0331825 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 2,377E-03 0,03299397 ! cellular response to starvation GO:0009267 37 22 1,000 2,377E-03 0,03280756 ! cell aging GO:0007569 48 22 1,000 2,377E-03 0,03262325 ! peptidyl-serine modification GO:0018209 50 22 1,000 2,377E-03 0,03244099 ! regulation of peptidase activity GO:0052547 150 82 2,000 2,548E-03 0,03457693 ! positive regulation of DNA replication GO:0045740 44 23 1,000 2,598E-03 0,03506259 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 2,598E-03 0,03486994 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 1,000 2,598E-03 0,0346794 GO:0060415|muscle tissue morphogenesis, ! fatty acid transport GO:0015908 47 23 1,000 2,598E-03 0,03449092 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 2,828E-03 0,03734277 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 1,000 2,828E-03 0,03714201 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 2,828E-03 0,03694338 ! sex determination GO:0007530 48 24 1,000 2,828E-03 0,03674688 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 2,828E-03 0,03655245 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 3,067E-03 0,03943703 ! keratinization GO:0031424 37 25 1,000 3,067E-03 0,03923056 ! negative regulation of DNA replication GO:0008156 45 25 1,000 3,067E-03 0,03902623 ! interaction with host GO:0051701 66 25 1,000 3,067E-03 0,03882402 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 3,067E-03 0,0386239 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 3,316E-03 0,0415387 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 3,316E-03 0,04132677 ! negative regulation of cell development GO:0010721 83 26 1,000 3,316E-03 0,04111699 GO:0050768|negative regulation of neurogenesis, ! mitochondrial membrane organization GO:0007006 60 27 1,000 3,573E-03 0,04408734 ! response to starvation GO:0042594 47 27 1,000 3,573E-03 0,0438658 ! cellular response to nutrient levels GO:0031669 45 27 1,000 3,573E-03 0,04364647 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 3,84E-03 0,04666979 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 3,84E-03 0,04643875 ! base-excision repair GO:0006284 41 28 1,000 3,84E-03 0,04620999 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 1,000 3,84E-03 0,04598347 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 3,84E-03 0,04575916 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 4,093E-03 0,04853687 ! tissue homeostasis GO:0001894 50 30 1,000 4,4E-03 0,05192731 GO:0048871|multicellular organismal homeostasis, ! skeletal muscle tissue development GO:0007519 223 100 2,000 4,457E-03 0,05234498 GO:0060538|skeletal muscle organ development, ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 4,693E-03 0,05485957 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 4,995E-03 0,05811351 ! regulation of pH GO:0006885 56 33 1,000 5,306E-03 0,06143777 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 5,306E-03 0,06114797 ! response to ionizing radiation GO:0010212 74 33 1,000 5,306E-03 0,06086089 ! negative regulation of protein transport GO:0051224 74 33 1,000 5,306E-03 0,06057649 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 5,626E-03 0,06392605 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 5,954E-03 0,06734207 ! calcium-mediated signaling GO:0019722 67 35 1,000 5,954E-03 0,06703173 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 6,291E-03 0,07049807 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 6,99E-03 0,07797315 ! cyclic nucleotide metabolic process GO:0009187 69 38 1,000 6,99E-03 0,07761872 ! glycogen metabolic process GO:0005977 63 38 1,000 6,99E-03 0,07726751 ! glucan metabolic process GO:0044042 64 39 1,000 7,352E-03 0,08090396 GO:0006073|cellular glucan metabolic process, ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 8,101E-03 0,0887474 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 8,101E-03 0,0883512 ! T cell differentiation GO:0030217 93 42 1,000 8,488E-03 0,09215919 ! striated muscle cell differentiation GO:0051146 91 43 1,000 8,883E-03 0,09602161 ! monocarboxylic acid transport GO:0015718 93 43 1,000 8,883E-03 0,09559861 ! energy reserve metabolic process GO:0006112 76 44 1,000 9,286E-03 0,0994988 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 9,286E-03 0,09906431 ! double-strand break repair GO:0006302 85 44 1,000 9,286E-03 0,09863359 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 9,697E-03 0,10255501 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 9,697E-03 0,10211297 ! keratinocyte differentiation GO:0030216 81 45 1,000 9,697E-03 0,10167471 ! B cell differentiation GO:0030183 124 45 1,000 9,697E-03 0,10124021 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 0,01011633 0,10516677 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,01097835 0,11364454 ! mitochondrial transport GO:0006839 94 48 1,000 0,01097835 0,11316503 ! endosome transport GO:0016197 127 48 1,000 0,01097835 0,11268955 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,01097835 0,11221804 ! protein homooligomerization GO:0051260 84 49 1,000 0,01142111 0,11625741 ! activation of caspase activity GO:0006919 95 50 1,000 0,01187163 0,12034192 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,01187163 0,11984464 ! amino acid activation GO:0043038 98 52 1,000 0,01279574 0,12864192 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of growth GO:0045927 96 53 1,000 0,01326921 0,13285524 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,01326921 0,13231297 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,01375022 0,13655201 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,01423872 0,14083078 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 1,000 0,01423872 0,14026292 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,01473466 0,14456536 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,01523798 0,1489055 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,01523798 0,14831225 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,01523798 0,14772371 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,01574862 0,15207066 ! aging GO:0007568 112 58 1,000 0,01574862 0,15147196 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01574862 0,15087795 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01635139 0,15604082 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01635139 0,15543366 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01635139 0,1548312 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01635139 0,1542334 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01635139 0,15364019 ! neuron fate determination GO:0048664 7 5 0,000 0,01635139 0,15305153 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01635139 0,15246736 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01635139 0,15188764 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01635139 0,15131231 ! polyol transport GO:0015791 12 5 0,000 0,01635139 0,15074132 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01635139 0,15017462 ! response to superoxide GO:0000303 10 5 0,000 0,01635139 0,14961217 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01635139 0,14905392 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01635139 0,14849981 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01635139 0,14794981 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01635139 0,14740387 ! female meiosis GO:0007143 10 5 0,000 0,01635139 0,14686195 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01635139 0,14632399 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01635139 0,14578996 ! hypothalamus development GO:0021854 9 5 0,000 0,01635139 0,14525982 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01635139 0,14473351 ! cobalt ion transport GO:0006824 11 5 0,000 0,01635139 0,14421101 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01635139 0,14369226 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01635139 0,14317724 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01635139 0,14266589 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01635139 0,14215818 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01635139 0,14165408 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01635139 0,14115353 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01635139 0,14065651 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01635139 0,14016298 ! transposition GO:0032196 9 5 0,000 0,01635139 0,1396729 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01635139 0,13918624 ! negative chemotaxis GO:0050919 16 5 0,000 0,01635139 0,13870295 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01635139 0,13822301 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01635139 0,13774638 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01635139 0,13727302 ! behavioral response to pain GO:0048266 10 5 0,000 0,01635139 0,13680291 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01635139 0,13633601 ! Notch receptor processing GO:0007220 11 5 0,000 0,01635139 0,13587228 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01635139 0,13541169 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01635139 0,13495422 ! micturition GO:0060073 9 5 0,000 0,01635139 0,13449983 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01635139 0,13404849 ! copulation GO:0007620 9 5 0,000 0,01635139 0,13360017 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01635139 0,13315483 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01635139 0,13271246 ! bioluminescence GO:0008218 9 5 0,000 0,01635139 0,13227301 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01635139 0,13183647 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01635139 0,13140279 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01635139 0,13097197 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01635139 0,13054395 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01635139 0,13011873 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01635139 0,12969626 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01635139 0,12927654 ! grooming behavior GO:0007625 6 5 0,000 0,01635139 0,12885951 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01635139 0,12844518 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01635139 0,12803349 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01635139 0,12762444 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01635139 0,12721799 ! response to protozoan GO:0001562 13 5 0,000 0,01635139 0,12681413 ! lymph vessel development GO:0001945 10 5 0,000 0,01635139 0,12641282 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01635139 0,12601404 ! endochondral ossification GO:0001958 17 5 0,000 0,01635139 0,12561777 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01635139 0,12522398 ! single strand break repair GO:0000012 8 5 0,000 0,01635139 0,12483266 ! parathyroid gland development GO:0060017 14 5 0,000 0,01635139 0,12444377 ! anagen GO:0042640 7 5 0,000 0,01635139 0,1240573 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01635139 0,12367322 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01635139 0,12329151 ! cytokine secretion GO:0050663 15 5 0,000 0,01635139 0,12291215 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01635139 0,12253512 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01635139 0,1221604 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01635139 0,12178796 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01635139 0,12141778 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01635139 0,12104985 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01635139 0,12068414 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01635139 0,12032063 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01635139 0,11995931 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01635139 0,11960015 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01635139 0,11924313 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01635139 0,11888824 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01635139 0,11853546 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01635139 0,11818476 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01635139 0,11783613 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01635139 0,11748956 ! microvillus organization GO:0032528 8 5 0,000 0,01635139 0,11714501 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01635139 0,11680248 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01635139 0,11646195 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01635139 0,1161234 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01635139 0,11578681 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01635139 0,11545217 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01635139 0,11511945 ! polyol catabolic process GO:0046174 9 5 0,000 0,01635139 0,11478865 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01635139 0,11445974 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01635139 0,11413271 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01635139 0,11380755 ! muscle cell migration GO:0014812 8 5 0,000 0,01635139 0,11348423 ! mitochondrial fission GO:0000266 8 5 0,000 0,01635139 0,11316275 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01635139 0,11284308 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01635139 0,11252521 ! mRNA transcription GO:0009299 10 5 0,000 0,01635139 0,11220913 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01635139 0,11189482 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01635139 0,11158226 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01635139 0,11127145 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01635139 0,11096236 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01635139 0,11065499 ! monocyte activation GO:0042117 10 5 0,000 0,01635139 0,11034931 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01635139 0,11004532 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01635139 0,10974299 ! response to food GO:0032094 6 5 0,000 0,01635139 0,10944233 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01635139 0,1091433 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01635139 0,10884591 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01635139 0,10855013 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01635139 0,10825596 ! forebrain neuron development GO:0021884 13 5 0,000 0,01635139 0,10796338 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01635139 0,10767237 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01635139 0,10738293 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01635139 0,10709504 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01635139 0,10680869 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01635139 0,10652387 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01635139 0,10624056 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01635139 0,10595875 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01635139 0,10567844 ! lipid glycosylation GO:0030259 7 5 0,000 0,01635139 0,1053996 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01635139 0,10512224 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01635139 0,10484632 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01635139 0,10457186 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01635139 0,10429882 ! basic amino acid transport GO:0015802 12 5 0,000 0,01635139 0,10402721 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01635139 0,10375701 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01635139 0,10348821 ! actin nucleation GO:0045010 11 5 0,000 0,01635139 0,1032208 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01635139 0,10295477 ! depurination GO:0045007 5 5 0,000 0,01635139 0,1026901 ! depyrimidination GO:0045008 10 5 0,000 0,01635139 0,10242679 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01635139 0,10216483 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01635139 0,10190421 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01635139 0,10164491 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01635139 0,10138693 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01635139 0,10113025 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01635139 0,10087487 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01635139 0,10062078 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01635139 0,10036796 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01635139 0,10011642 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01635139 0,09986612 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01635139 0,09961708 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01635139 0,09936928 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01635139 0,0991227 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01635139 0,09887735 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01635139 0,09863321 ! response to arsenic GO:0046685 11 5 0,000 0,01635139 0,09839027 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01635139 0,09814852 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01635139 0,09790796 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01635139 0,09766858 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01635139 0,09743036 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01635139 0,09719331 ! response to mercury ion GO:0046689 8 5 0,000 0,01635139 0,0969574 ! response to cadmium ion GO:0046686 7 5 0,000 0,01635139 0,09672264 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01635139 0,09648901 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01635139 0,09625651 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01635139 0,09602512 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01635139 0,09579484 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01635139 0,09556567 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01635139 0,09533759 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01635139 0,09511059 ! decidualization GO:0046697 11 5 0,000 0,01635139 0,09488468 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01635139 0,09465983 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01635139 0,09443605 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01635139 0,09421332 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01635139 0,09399165 ! embryonic cleavage GO:0040016 6 5 0,000 0,01635139 0,09377101 ! peroxisome fission GO:0016559 5 5 0,000 0,01635139 0,0935514 ! histone demethylation GO:0016577 13 5 0,000 0,01635139 0,09333283 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01635139 0,09311527 ! mitotic recombination GO:0006312 9 5 0,000 0,01635139 0,09289872 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01635139 0,09268318 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01635139 0,09246863 ! metaphase plate congression GO:0051310 7 5 0,000 0,01635139 0,09225508 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01635139 0,09204251 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01635139 0,09183092 ! enteric nervous system development GO:0048484 8 5 0,000 0,01635139 0,0916203 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01635139 0,09141064 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01635139 0,09120194 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01635139 0,09099419 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01635139 0,09078739 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01635139 0,09058152 ! B cell homeostasis GO:0001782 13 5 0,000 0,01635139 0,09037658 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01635139 0,09017257 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01635139 0,08996948 ! metaphase GO:0051323 11 5 0,000 0,01635139 0,0897673 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01635139 0,08956603 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01635139 0,08936566 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01635139 0,08916618 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01635139 0,08896759 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01635139 0,08876989 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01635139 0,08857306 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01635139 0,0883771 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01635139 0,08818201 ! response to redox state GO:0051775 6 5 0,000 0,01635139 0,08798777 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01635139 0,08779439 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01635139 0,08760186 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01635139 0,08741017 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01635139 0,08721932 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01635139 0,0870293 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01635139 0,08684011 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01635139 0,08665173 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01635139 0,08646418 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01635139 0,08627743 ! striatum development GO:0021756 14 5 0,000 0,01635139 0,08609149 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01635139 0,08590634 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01635139 0,08572199 ! glial cell migration GO:0008347 10 5 0,000 0,01635139 0,08553844 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01635139 0,08535566 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01635139 0,08517367 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01635139 0,08499245 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01635139 0,08481199 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01635139 0,08463231 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01635139 0,08445338 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01635139 0,08427521 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01635139 0,08409779 ! neuroprotection GO:0043526 8 5 0,000 0,01635139 0,08392111 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01635139 0,08374518 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01635139 0,08356998 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01635139 0,08339551 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01635139 0,08322177 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01635139 0,08304875 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01635139 0,08287645 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01635139 0,08270486 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01635139 0,08253399 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01635139 0,08236381 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01635139 0,08219434 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01635139 0,08202556 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01635139 0,08185748 ! spindle assembly GO:0051225 6 5 0,000 0,01635139 0,08169008 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01635139 0,08152337 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01635139 0,08135733 ! protein palmitoylation GO:0018345 12 5 0,000 0,01635139 0,08119197 ! drug metabolic process GO:0017144 7 5 0,000 0,01635139 0,08102728 ! stem cell division GO:0017145 11 5 0,000 0,01635139 0,08086326 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01635139 0,0806999 ! organ regeneration GO:0031100 7 5 0,000 0,01635139 0,0805372 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01635139 0,08037515 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01635139 0,08021375 ! viral reproductive process GO:0022415 132 62 1,000 0,01786342 0,08745557 ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,01952389 0,09539375 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01958972 0,09552431 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01958972 0,09533403 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01958972 0,0951445 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01958972 0,09495572 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01958972 0,09476769 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01958972 0,0945804 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01958972 0,09439385 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01958972 0,09420803 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01958972 0,09402295 ! response to oxygen radical GO:0000305 11 6 0,000 0,01958972 0,09383859 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01958972 0,09365495 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01958972 0,09347203 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01958972 0,09328983 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01958972 0,09310833 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01958972 0,09292754 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01958972 0,09274744 ! forebrain regionalization GO:0021871 9 6 0,000 0,01958972 0,09256805 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01958972 0,09238935 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01958972 0,09221133 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01958972 0,092034 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01958972 0,09185735 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01958972 0,09168138 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01958972 0,09150608 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01958972 0,09133145 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01958972 0,09115749 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01958972 0,09098419 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01958972 0,09081154 ! malate metabolic process GO:0006108 13 6 0,000 0,01958972 0,09063955 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01958972 0,09046821 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01958972 0,09029751 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01958972 0,09012746 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01958972 0,08995805 ! protein refolding GO:0042026 15 6 0,000 0,01958972 0,08978927 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01958972 0,08962113 ! opsonization GO:0008228 8 6 0,000 0,01958972 0,08945361 ! mating behavior GO:0007617 7 6 0,000 0,01958972 0,08928672 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01958972 0,08912045 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01958972 0,0889548 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01958972 0,08878976 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01958972 0,08862534 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01958972 0,08846152 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01958972 0,08829831 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01958972 0,08813569 ! toxin metabolic process GO:0009404 11 6 0,000 0,01958972 0,08797368 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01958972 0,08781226 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01958972 0,08765143 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01958972 0,08749119 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01958972 0,08733154 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01958972 0,08717246 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01958972 0,08701397 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01958972 0,08685605 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01958972 0,0866987 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01958972 0,08654192 ! thymic T cell selection GO:0045061 16 6 0,000 0,01958972 0,08638571 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01958972 0,08623006 ! protein lipoylation GO:0009249 10 6 0,000 0,01958972 0,08607497 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01958972 0,08592043 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01958972 0,08576645 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01958972 0,08561303 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01958972 0,08546015 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01958972 0,08530781 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01958972 0,08515602 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01958972 0,08500476 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01958972 0,08485404 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01958972 0,08470386 ! hyperosmotic response GO:0006972 10 6 0,000 0,01958972 0,08455421 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01958972 0,08440508 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01958972 0,08425648 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01958972 0,0841084 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01958972 0,08396084 ! urea metabolic process GO:0019627 7 6 0,000 0,01958972 0,0838138 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01958972 0,08366728 ! neutrophil activation GO:0042119 7 6 0,000 0,01958972 0,08352126 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01958972 0,08337575 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01958972 0,08323075 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01958972 0,08308625 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01958972 0,08294226 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01958972 0,08279876 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01958972 0,08265575 ! neuron apoptosis GO:0051402 15 6 0,000 0,01958972 0,08251324 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01958972 0,08237122 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01958972 0,08222969 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01958972 0,08208865 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01958972 0,08194808 ! carnitine transport GO:0015879 10 6 0,000 0,01958972 0,081808 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01958972 0,0816684 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01958972 0,08152927 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01958972 0,08139061 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01958972 0,08125243 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01958972 0,08111471 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01958972 0,08097746 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01958972 0,08084068 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01958972 0,08070435 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01958972 0,08056849 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01958972 0,08043308 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01958972 0,08029812 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01958972 0,08016362 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01958972 0,08002957 ! response to UV-C GO:0010225 14 6 0,000 0,01958972 0,07989596 ! astrocyte development GO:0014002 16 6 0,000 0,01958972 0,0797628 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01958972 0,07963009 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01958972 0,07949781 ! interaction with symbiont GO:0051702 14 6 0,000 0,01958972 0,07936597 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01958972 0,07923457 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01958972 0,07910361 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01958972 0,07897307 ! response to copper ion GO:0046688 10 6 0,000 0,01958972 0,07884297 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01958972 0,07871329 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01958972 0,07858404 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01958972 0,07845522 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01958972 0,07832681 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01958972 0,07819883 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01958972 0,07807126 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01958972 0,07794411 ! hair follicle maturation GO:0048820 8 6 0,000 0,01958972 0,07781737 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01958972 0,07769104 ! Schwann cell development GO:0014044 15 6 0,000 0,01958972 0,07756512 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01958972 0,07743961 ! response to pheromone GO:0019236 6 6 0,000 0,01958972 0,07731451 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01958972 0,07718981 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01958972 0,07706551 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01958972 0,07694161 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01958972 0,07681811 ! subpallium development GO:0021544 15 6 0,000 0,01958972 0,076695 ! neural tube patterning GO:0021532 8 6 0,000 0,01958972 0,07657229 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01958972 0,07644997 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01958972 0,07632804 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01958972 0,0762065 ! G2 phase GO:0051319 16 6 0,000 0,01958972 0,07608534 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01958972 0,07596457 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01958972 0,07584419 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01958972 0,07572418 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01958972 0,07560455 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01958972 0,0754853 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01958972 0,07536643 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01958972 0,07524793 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01958972 0,0751298 ! receptor internalization GO:0031623 11 6 0,000 0,01958972 0,07501204 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01958972 0,07489465 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01958972 0,07477763 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01958972 0,07466097 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01958972 0,07454468 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01958972 0,07442874 ! protein deubiquitination GO:0016579 16 6 0,000 0,01958972 0,07431317 ! protein destabilization GO:0031648 9 6 0,000 0,01958972 0,07419796 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01958972 0,0740831 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01958972 0,0739686 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01958972 0,07385445 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01958972 0,07374065 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01958972 0,0736272 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01958972 0,0735141 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01958972 0,07340135 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01958972 0,07328895 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01958972 0,07317688 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01958972 0,07306516 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01958972 0,07295378 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01958972 0,07284274 ! neural plate development GO:0001840 9 6 0,000 0,01958972 0,07273204 ! catecholamine transport GO:0051937 9 6 0,000 0,01958972 0,07262167 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01958972 0,07251164 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01958972 0,07240194 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01958972 0,07229257 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01958972 0,07218353 ! maternal placenta development GO:0001893 12 6 0,000 0,01958972 0,07207482 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01958972 0,07196644 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01958972 0,07185838 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01958972 0,07175065 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01958972 0,07164324 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01958972 0,07153615 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01958972 0,07142938 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01958972 0,07132292 GO:0055081|anion homeostasis, ! negative regulation of cell growth GO:0030308 142 67 1,000 0,02066553 0,0751278 ! viral reproduction GO:0016032 142 68 1,000 0,02124658 0,07712541 ! regulation of lipase activity GO:0060191 137 68 1,000 0,02124658 0,07701098 ! negative regulation of cell size GO:0045792 144 69 1,000 0,0218344 0,07902436 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,0218344 0,07890746 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,0218344 0,0787909 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,02242893 0,08081693 ! tRNA transcription GO:0009304 17 7 0,000 0,02281747 0,08209586 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02281747 0,08197513 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02281747 0,08185476 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02281747 0,08173474 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02281747 0,08161507 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02281747 0,08149575 ! sleep GO:0030431 16 7 0,000 0,02281747 0,08137677 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02281747 0,08125815 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02281747 0,08113987 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02281747 0,08102193 ! prostate gland development GO:0030850 14 7 0,000 0,02281747 0,08090434 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02281747 0,08078709 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02281747 0,08067017 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02281747 0,0805536 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02281747 0,08043736 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02281747 0,08032146 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02281747 0,08020588 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02281747 0,08009065 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02281747 0,07997574 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02281747 0,07986116 ! glycolipid transport GO:0046836 11 7 0,000 0,02281747 0,07974691 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02281747 0,07963299 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02281747 0,07951939 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,02281747 0,07940611 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02281747 0,07929316 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02281747 0,07918053 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02281747 0,07906821 ! mRNA stabilization GO:0048255 18 7 0,000 0,02281747 0,07895622 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02281747 0,07884454 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02281747 0,07873318 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02281747 0,07862213 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02281747 0,07851139 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02281747 0,07840097 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02281747 0,07829086 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02281747 0,07818105 ! lipoprotein transport GO:0042953 14 7 0,000 0,02281747 0,07807155 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02281747 0,07796236 ! rhythmic behavior GO:0007622 17 7 0,000 0,02281747 0,07785348 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02281747 0,0777449 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02281747 0,07763662 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02281747 0,07752864 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02281747 0,07742096 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02281747 0,07731358 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02281747 0,0772065 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02281747 0,07709971 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02281747 0,07699322 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02281747 0,07688702 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02281747 0,07678112 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02281747 0,0766755 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02281747 0,07657018 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02281747 0,07646514 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02281747 0,0763604 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02281747 0,07625594 ! spinal cord patterning GO:0021511 14 7 0,000 0,02281747 0,07615176 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02281747 0,07604787 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02281747 0,07594426 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02281747 0,07584094 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02281747 0,07573789 ! adrenal gland development GO:0030325 17 7 0,000 0,02281747 0,07563513 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02281747 0,07553264 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02281747 0,07543043 ! ovulation GO:0030728 10 7 0,000 0,02281747 0,0753285 ! adenohypophysis development GO:0021984 11 7 0,000 0,02281747 0,07522684 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02281747 0,07512546 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02281747 0,07502435 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02281747 0,07492351 ! microtubule nucleation GO:0007020 21 7 0,000 0,02281747 0,07482294 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02281747 0,07472264 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02281747 0,07462261 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02281747 0,07452285 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02281747 0,07442335 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02281747 0,07432412 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02281747 0,07422515 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02281747 0,07412645 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02281747 0,07402801 ! galactose metabolic process GO:0006012 13 7 0,000 0,02281747 0,07392983 ! vesicle fusion GO:0006906 20 7 0,000 0,02281747 0,07383191 ! response to dietary excess GO:0002021 8 7 0,000 0,02281747 0,07373425 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02281747 0,07363684 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02281747 0,0735397 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02281747 0,07344281 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02281747 0,07334617 ! nucleoside transport GO:0015858 11 7 0,000 0,02281747 0,07324979 ! nucleoside salvage GO:0043174 11 7 0,000 0,02281747 0,07315366 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02281747 0,07305779 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02281747 0,07296216 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02281747 0,07286678 ! parturition GO:0007567 16 7 0,000 0,02281747 0,07277166 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02281747 0,07267678 ! rRNA modification GO:0000154 14 7 0,000 0,02281747 0,07258215 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02281747 0,07248776 ! spindle checkpoint GO:0031577 16 7 0,000 0,02281747 0,07239362 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02281747 0,07229973 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02281747 0,07220608 ! monocyte differentiation GO:0030224 16 7 0,000 0,02281747 0,07211266 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02281747 0,0720195 ! centrosome duplication GO:0051298 14 7 0,000 0,02281747 0,07192657 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02281747 0,07183388 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02281747 0,07174143 ! fibrinolysis GO:0042730 11 7 0,000 0,02281747 0,07164922 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02281747 0,07155724 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02281747 0,0714655 ! eating behavior GO:0042755 8 7 0,000 0,02281747 0,07137399 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02281747 0,07128272 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02281747 0,07119169 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02281747 0,07110088 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02281747 0,07101031 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02281747 0,07091996 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02281747 0,07082985 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02281747 0,07073996 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02281747 0,0706503 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02281747 0,07056087 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02281747 0,07047167 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02281747 0,07038269 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02281747 0,07029393 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02281747 0,0702054 ! histone ubiquitination GO:0016574 9 7 0,000 0,02281747 0,07011709 ! regulation of meiosis GO:0040020 12 7 0,000 0,02281747 0,07002901 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02281747 0,06994114 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02281747 0,0698535 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02281747 0,06976607 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02281747 0,06967886 ! transcription termination GO:0006353 14 7 0,000 0,02281747 0,06959187 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02281747 0,0695051 ! anaphase GO:0051322 18 7 0,000 0,02281747 0,06941854 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02281747 0,0693322 ! axonal fasciculation GO:0007413 19 7 0,000 0,02281747 0,06924607 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02281747 0,06916016 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02281747 0,06907446 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02281747 0,06898897 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02281747 0,0689037 ! diuresis GO:0030146 12 7 0,000 0,02281747 0,06881863 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02281747 0,06873377 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02281747 0,06864913 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02281747 0,06856469 ! antibiotic transport GO:0042891 9 7 0,000 0,02281747 0,06848045 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02281747 0,06839643 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02281747 0,06831261 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02281747 0,068229 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02281747 0,06814559 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02281747 0,06806238 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02281747 0,06797938 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02281747 0,06789658 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02281747 0,06781398 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02281747 0,06773158 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02281747 0,06764938 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02281747 0,06756738 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02281747 0,06748558 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02281747 0,06740398 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02281747 0,06732257 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02281747 0,06724136 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02281747 0,06716035 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02281747 0,06707953 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02281747 0,06699891 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02281747 0,06691848 ! muscle adaptation GO:0043500 13 7 0,000 0,02281747 0,06683824 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02281747 0,06675819 ! retina homeostasis GO:0001895 12 7 0,000 0,02281747 0,06667834 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02281747 0,06659867 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02281747 0,0665192 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02281747 0,06643992 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02281747 0,06636082 ! actin filament organization GO:0007015 167 72 1,000 0,02363792 0,06866521 ! B cell activation GO:0042113 179 72 1,000 0,02363792 0,06858366 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,02487316 0,07208202 ! organelle localization GO:0051640 155 74 1,000 0,02487316 0,07199661 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,02550051 0,07372513 GO:0090046|regulation of transcription regulator activity, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02603469 0,07518057 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02603469 0,07509181 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02603469 0,07500325 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02603469 0,07491491 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02603469 0,07482678 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02603469 0,07473885 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02603469 0,07465113 ! male meiosis GO:0007140 9 8 0,000 0,02603469 0,07456361 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02603469 0,0744763 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02603469 0,07438919 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02603469 0,07430229 ! meiotic prophase I GO:0007128 14 8 0,000 0,02603469 0,07421559 ! response to zinc ion GO:0010043 12 8 0,000 0,02603469 0,07412909 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,02603469 0,07404279 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02603469 0,0739567 ! oligopeptide transport GO:0006857 16 8 0,000 0,02603469 0,0738708 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02603469 0,0737851 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02603469 0,0736996 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02603469 0,0736143 ! signal peptide processing GO:0006465 12 8 0,000 0,02603469 0,0735292 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02603469 0,07344429 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02603469 0,07335958 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02603469 0,07327507 ! succinate metabolic process GO:0006105 17 8 0,000 0,02603469 0,07319075 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02603469 0,07310662 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02603469 0,07302269 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02603469 0,07293894 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02603469 0,07285539 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02603469 0,07277204 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02603469 0,07268887 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02603469 0,07260589 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02603469 0,0725231 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02603469 0,0724405 ! reflex GO:0060004 17 8 0,000 0,02603469 0,07235809 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02603469 0,07227586 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02603469 0,07219382 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02603469 0,07211197 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02603469 0,0720303 ! pigment granule organization GO:0048753 17 8 0,000 0,02603469 0,07194882 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02603469 0,07186752 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02603469 0,07178641 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02603469 0,07170548 ! histidine catabolic process GO:0006548 10 8 0,000 0,02603469 0,07162473 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02603469 0,07154416 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02603469 0,07146377 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02603469 0,07138357 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02603469 0,07130354 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02603469 0,07122369 ! melanin metabolic process GO:0006582 17 8 0,000 0,02603469 0,07114403 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02603469 0,07106454 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02603469 0,07098522 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02603469 0,07090609 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02603469 0,07082713 ! macrophage activation GO:0042116 13 8 0,000 0,02603469 0,07074834 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02603469 0,07066973 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02603469 0,0705913 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02603469 0,07051304 ! purine salvage GO:0043101 12 8 0,000 0,02603469 0,07043495 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02603469 0,07035703 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02603469 0,07027929 ! osteoblast development GO:0002076 17 8 0,000 0,02603469 0,07020172 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02603469 0,07012432 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02603469 0,07004709 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02603469 0,06997003 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02603469 0,06989314 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02603469 0,06981642 ! response to UV-B GO:0010224 17 8 0,000 0,02603469 0,06973987 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02603469 0,06966348 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02603469 0,06958726 ! intermediate filament organization GO:0045109 12 8 0,000 0,02603469 0,06951121 ! cellular extravasation GO:0045123 13 8 0,000 0,02603469 0,06943533 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02603469 0,06935961 ! response to antibiotic GO:0046677 11 8 0,000 0,02603469 0,06928405 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02603469 0,06920866 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02603469 0,06913343 ! DNA topological change GO:0006265 12 8 0,000 0,02603469 0,06905837 ! response to tropane GO:0014073 15 8 0,000 0,02603469 0,06898347 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02603469 0,06890873 ! melanosome transport GO:0032402 13 8 0,000 0,02603469 0,06883415 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02603469 0,06875974 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02603469 0,06868548 ! mast cell activation GO:0045576 14 8 0,000 0,02603469 0,06861139 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02603469 0,06853746 ! gas homeostasis GO:0033483 14 8 0,000 0,02603469 0,06846368 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02603469 0,06839006 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02603469 0,0683166 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02603469 0,0682433 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02603469 0,06817016 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02603469 0,06809717 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02603469 0,06802434 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02603469 0,06795167 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02603469 0,06787915 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02603469 0,06780678 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02603469 0,06773457 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02603469 0,06766251 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02603469 0,0675906 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02603469 0,06751885 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02603469 0,06744725 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02603469 0,0673758 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02603469 0,06730451 ! hormone catabolic process GO:0042447 17 8 0,000 0,02603469 0,06723336 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02603469 0,06716236 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02603469 0,06709152 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02603469 0,06702082 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02603469 0,06695027 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02603469 0,06687987 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02603469 0,06680962 ! adult feeding behavior GO:0008343 10 8 0,000 0,02603469 0,06673952 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02603469 0,06666956 ! ATP catabolic process GO:0006200 11 8 0,000 0,02603469 0,06659975 ! blastocyst growth GO:0001832 19 8 0,000 0,02603469 0,06653008 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02603469 0,06646056 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02603469 0,06639119 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02603469 0,06632196 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02603469 0,06625287 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02603469 0,06618393 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02603469 0,06611513 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02603469 0,06604648 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02603469 0,06597797 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02603469 0,06590959 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02603469 0,06584137 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02603469 0,06577328 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02603469 0,06570533 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02603469 0,06563752 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02603469 0,06556985 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02603469 0,06550233 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02603469 0,06543494 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02603469 0,06536769 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02603469 0,06530057 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02603469 0,0652336 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,02613426 0,06541599 ! axon extension GO:0048675 16 9 0,000 0,02924141 0,0731185 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02924141 0,07304373 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02924141 0,07296912 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02924141 0,07289467 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02924141 0,07282036 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02924141 0,0727462 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02924141 0,0726722 ! reproductive behavior GO:0019098 22 9 0,000 0,02924141 0,07259835 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02924141 0,07252464 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02924141 0,07245109 GO:0010469|regulation of receptor activity, ! UTP metabolic process GO:0046051 10 9 0,000 0,02924141 0,07237768 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02924141 0,07230442 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02924141 0,07223132 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02924141 0,07215836 ! artery development GO:0060840 25 9 0,000 0,02924141 0,07208554 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02924141 0,07201287 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02924141 0,07194035 ! equilibrioception GO:0050957 20 9 0,000 0,02924141 0,07186798 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02924141 0,07179575 ! chemosensory behavior GO:0007635 21 9 0,000 0,02924141 0,07172367 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02924141 0,07165173 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02924141 0,07157993 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02924141 0,07150828 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02924141 0,07143677 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02924141 0,07136541 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02924141 0,07129418 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02924141 0,0712231 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02924141 0,07115216 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02924141 0,07108136 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02924141 0,07101071 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02924141 0,07094019 ! protein targeting to ER GO:0045047 25 9 0,000 0,02924141 0,07086981 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02924141 0,07079958 ! T cell selection GO:0045058 27 9 0,000 0,02924141 0,07072948 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02924141 0,07065952 ! glycine catabolic process GO:0006546 15 9 0,000 0,02924141 0,0705897 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02924141 0,07052001 ! endosome organization GO:0007032 20 9 0,000 0,02924141 0,07045047 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02924141 0,07038106 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02924141 0,07031178 ! mannose metabolic process GO:0006013 13 9 0,000 0,02924141 0,07024265 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02924141 0,07017365 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02924141 0,07010478 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02924141 0,07003605 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02924141 0,06996746 ! receptor clustering GO:0043113 20 9 0,000 0,02924141 0,06989899 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02924141 0,06983067 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02924141 0,06976247 ! retinol metabolic process GO:0042572 20 9 0,000 0,02924141 0,06969441 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02924141 0,06962648 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02924141 0,06955869 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02924141 0,06949102 ! macrophage differentiation GO:0030225 15 9 0,000 0,02924141 0,06942349 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02924141 0,06935609 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02924141 0,06928882 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02924141 0,06922168 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02924141 0,06915467 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02924141 0,06908779 ! response to amine stimulus GO:0014075 13 9 0,000 0,02924141 0,06902104 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02924141 0,06895441 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02924141 0,06888792 ! erythrocyte development GO:0048821 17 9 0,000 0,02924141 0,06882155 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02924141 0,06875531 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02924141 0,0686892 ! renal water homeostasis GO:0003091 15 9 0,000 0,02924141 0,06862322 ! postreplication repair GO:0006301 25 9 0,000 0,02924141 0,06855736 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02924141 0,06849163 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02924141 0,06842603 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02924141 0,06836055 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02924141 0,06829519 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02924141 0,06822996 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02924141 0,06816486 ! sterol catabolic process GO:0016127 14 9 0,000 0,02924141 0,06809988 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02924141 0,06803502 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02924141 0,06797029 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02924141 0,06790568 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02924141 0,06784119 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02924141 0,06777682 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02924141 0,06771258 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02924141 0,06764846 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02924141 0,06758446 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02924141 0,06752058 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02924141 0,06745682 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02924141 0,06739318 ! purine base metabolic process GO:0006144 25 9 0,000 0,02924141 0,06732966 ! pigment granule transport GO:0051904 17 9 0,000 0,02924141 0,06726626 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02924141 0,06720298 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02924141 0,06713982 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02924141 0,06707678 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02924141 0,06701386 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02924141 0,06695105 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02924141 0,06688836 ! mitochondrion localization GO:0051646 18 9 0,000 0,02924141 0,06682579 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,02939762 0,06711998 ! protein import into nucleus GO:0006606 174 82 1,000 0,03006887 0,06858846 ! response to drug GO:0042493 149 83 1,000 0,0307462 0,07006806 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,0307462 0,07000276 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,0307462 0,06993758 ! T cell activation GO:0042110 189 84 1,000 0,03142957 0,07142552 ! response to nutrient GO:0007584 135 84 1,000 0,03142957 0,07135914 ! cholesterol metabolic process GO:0008203 148 85 1,000 0,03211893 0,07285659 ! negative regulation of growth GO:0045926 168 85 1,000 0,03211893 0,072789 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03243766 0,0734432 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,03243766 0,0733752 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03243766 0,07330732 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03243766 0,07323957 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03243766 0,07317194 ! associative learning GO:0008306 21 10 0,000 0,03243766 0,07310444 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03243766 0,07303706 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03243766 0,07296981 ! phosphate transport GO:0006817 24 10 0,000 0,03243766 0,07290268 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03243766 0,07283567 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03243766 0,07276879 ! CTP metabolic process GO:0046036 11 10 0,000 0,03243766 0,07270203 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03243766 0,07263539 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03243766 0,07256887 ! GTP metabolic process GO:0046039 11 10 0,000 0,03243766 0,07250248 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03243766 0,07243621 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03243766 0,07237006 ! social behavior GO:0035176 29 10 0,000 0,03243766 0,07230402 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03243766 0,07223811 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03243766 0,07217232 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03243766 0,07210665 ! androgen metabolic process GO:0008209 17 10 0,000 0,03243766 0,0720411 ! phospholipid efflux GO:0033700 19 10 0,000 0,03243766 0,07197567 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03243766 0,07191036 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03243766 0,07184516 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03243766 0,07178008 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03243766 0,07171512 ! lung alveolus development GO:0048286 26 10 0,000 0,03243766 0,07165028 ! pathogenesis GO:0009405 17 10 0,000 0,03243766 0,07158556 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03243766 0,07152095 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03243766 0,07145646 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03243766 0,07139208 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03243766 0,07132782 ! endoderm development GO:0007492 18 10 0,000 0,03243766 0,07126368 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03243766 0,07119965 ! arginine catabolic process GO:0006527 17 10 0,000 0,03243766 0,07113574 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03243766 0,07107194 ! proline metabolic process GO:0006560 13 10 0,000 0,03243766 0,07100825 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03243766 0,07094468 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03243766 0,07088123 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03243766 0,07081788 ! V(D)J recombination GO:0033151 34 10 0,000 0,03243766 0,07075465 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03243766 0,07069154 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03243766 0,07062853 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03243766 0,07056564 ! B cell proliferation GO:0042100 19 10 0,000 0,03243766 0,07050286 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03243766 0,07044019 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03243766 0,07037763 ! multicellular organism growth GO:0035264 19 10 0,000 0,03243766 0,07031518 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03243766 0,07025285 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03243766 0,07019062 ! ruffle organization GO:0031529 17 10 0,000 0,03243766 0,07012851 ! epithelial cell development GO:0002064 21 10 0,000 0,03243766 0,0700665 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03243766 0,0700046 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03243766 0,06994282 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03243766 0,06988114 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03243766 0,06981957 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03243766 0,06975811 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03243766 0,06969676 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,03243766 0,06963551 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03243766 0,06957437 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03243766 0,06951334 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03243766 0,06945242 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03243766 0,0693916 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03243766 0,06933089 ! segment specification GO:0007379 15 10 0,000 0,03243766 0,06927029 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03243766 0,06920979 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03243766 0,0691494 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03243766 0,06908911 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03243766 0,06902893 ! response to dsRNA GO:0043331 23 10 0,000 0,03243766 0,06896885 ! DNA ligation GO:0006266 18 10 0,000 0,03243766 0,06890888 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03243766 0,06884901 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03243766 0,06878925 ! melanosome localization GO:0032400 16 10 0,000 0,03243766 0,06872958 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03243766 0,06867003 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03243766 0,06861057 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03243766 0,06855122 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03243766 0,06849197 ! induction of an organ GO:0001759 17 10 0,000 0,03243766 0,06843282 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03243766 0,06837378 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03243766 0,06831484 ! protein sumoylation GO:0016925 17 10 0,000 0,03243766 0,068256 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03243766 0,06819726 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03243766 0,06813862 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03243766 0,06808008 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03243766 0,06802164 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03243766 0,0679633 ! salivary gland development GO:0007431 28 10 0,000 0,03243766 0,06790507 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03243766 0,06784693 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03243766 0,06778889 ! midbrain development GO:0030901 14 10 0,000 0,03243766 0,06773095 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03243766 0,06767311 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03243766 0,06761537 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03243766 0,06755772 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03243766 0,06750018 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03243766 0,06744273 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03243766 0,06738538 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03243766 0,06732813 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03243766 0,06727098 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03243766 0,06721392 ! detection of calcium ion GO:0005513 24 10 0,000 0,03243766 0,06715696 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03243766 0,06710009 ! blastocyst formation GO:0001825 18 10 0,000 0,03243766 0,06704333 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03243766 0,06698665 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03243766 0,06693008 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03243766 0,0668736 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03243766 0,06681721 ! response to nicotine GO:0035094 20 10 0,000 0,03243766 0,06676092 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03243766 0,06670472 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03243766 0,06664862 ! mitochondrion organization GO:0007005 159 87 1,000 0,03351544 0,06880522 ! regulation of DNA binding GO:0051101 167 89 1,000 0,03493536 0,07166001 ! protein localization in nucleus GO:0034504 192 89 1,000 0,03493536 0,07159989 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03562348 0,072949 ! respiratory burst GO:0045730 17 11 0,000 0,03562348 0,07288791 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03562348 0,07282691 ! neuron fate specification GO:0048665 18 11 0,000 0,03562348 0,07276602 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03562348 0,07270523 ! thyroid gland development GO:0030878 26 11 0,000 0,03562348 0,07264454 ! synapsis GO:0007129 14 11 0,000 0,03562348 0,07258395 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03562348 0,07252347 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03562348 0,07246308 ! response to pain GO:0048265 27 11 0,000 0,03562348 0,0724028 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03562348 0,07234261 ! blood vessel remodeling GO:0001974 30 11 0,000 0,03562348 0,07228253 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,03562348 0,07222254 ! bone resorption GO:0045453 16 11 0,000 0,03562348 0,07216265 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03562348 0,07210287 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,03562348 0,07204318 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03562348 0,07198359 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03562348 0,0719241 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03562348 0,07186471 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03562348 0,07180541 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03562348 0,07174622 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03562348 0,07168712 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03562348 0,07162812 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03562348 0,07156921 ! UV protection GO:0009650 20 11 0,000 0,03562348 0,0715104 ! adult heart development GO:0007512 16 11 0,000 0,03562348 0,07145169 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03562348 0,07139308 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03562348 0,07133456 ! macroautophagy GO:0016236 19 11 0,000 0,03562348 0,07127613 ! temperature homeostasis GO:0001659 18 11 0,000 0,03562348 0,07121781 ! behavioral fear response GO:0001662 27 11 0,000 0,03562348 0,07115958 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03562348 0,07110144 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03562348 0,0710434 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03562348 0,07098545 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03562348 0,0709276 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03562348 0,07086984 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03562348 0,07081217 ! regulation of organ growth GO:0046620 14 11 0,000 0,03562348 0,0707546 ! pigment granule localization GO:0051875 20 11 0,000 0,03562348 0,07069712 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03562348 0,07063974 ! vasoconstriction GO:0042310 20 11 0,000 0,03562348 0,07058245 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03562348 0,07052525 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03562348 0,07046815 ! embryonic axis specification GO:0000578 19 11 0,000 0,03562348 0,07041113 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03562348 0,07035421 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03562348 0,07029738 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03562348 0,07024065 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03562348 0,070184 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03562348 0,07012745 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03562348 0,07007098 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03562348 0,07001461 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03562348 0,06995833 ! prophase GO:0051324 17 11 0,000 0,03562348 0,06990214 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03562348 0,06984604 ! nucleosome positioning GO:0016584 15 11 0,000 0,03562348 0,06979002 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03562348 0,0697341 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03562348 0,06967827 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03562348 0,06962253 ! apical protein localization GO:0045176 18 11 0,000 0,03562348 0,06956687 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03562348 0,06951131 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03562348 0,06945583 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,03562348 0,06940045 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03562348 0,06934515 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03562348 0,06928994 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03562348 0,06923481 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03562348 0,06917978 ! cholesterol efflux GO:0033344 21 11 0,000 0,03562348 0,06912483 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03562348 0,06906997 ! oocyte development GO:0048599 20 11 0,000 0,03562348 0,06901519 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03562348 0,06896051 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03562348 0,06890591 ! embryonic gut development GO:0048566 19 11 0,000 0,03562348 0,06885139 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03562348 0,06879696 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03562348 0,06874262 ! activation of innate immune response GO:0002218 16 11 0,000 0,03562348 0,06868837 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03562348 0,0686342 ! lysogeny GO:0030069 22 11 0,000 0,03562348 0,06858011 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03562348 0,06852611 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03562348 0,0684722 ! sequestering of metal ion GO:0051238 15 11 0,000 0,03562348 0,06841836 ! nucleus localization GO:0051647 22 11 0,000 0,03562348 0,06836462 ! ossification GO:0001503 205 91 1,000 0,03637832 0,06975843 ! bone development GO:0060348 206 92 1,000 0,03710834 0,07110249 ! vitamin metabolic process GO:0006766 153 93 1,000 0,03784398 0,07245521 ! sterol metabolic process GO:0016125 166 94 1,000 0,03858521 0,0738165 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0387989 0,07416722 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0387989 0,07410923 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,0387989 0,07405133 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,0387989 0,07399352 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0387989 0,0739358 ! protein complex disassembly GO:0043241 28 12 0,000 0,0387989 0,07387818 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0387989 0,07382064 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0387989 0,07376319 ! hippocampus development GO:0021766 29 12 0,000 0,0387989 0,07370583 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0387989 0,07364856 ! T cell proliferation GO:0042098 32 12 0,000 0,0387989 0,07359138 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0387989 0,07353429 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0387989 0,07347729 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0387989 0,07342037 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0387989 0,07336355 ! drug transport GO:0015893 16 12 0,000 0,0387989 0,07330681 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0387989 0,07325016 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0387989 0,07319359 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0387989 0,07313712 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0387989 0,07308073 ! focal adhesion formation GO:0048041 37 12 0,000 0,0387989 0,07302442 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0387989 0,07296821 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0387989 0,07291208 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0387989 0,07285603 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0387989 0,07280008 ! lipid digestion GO:0044241 21 12 0,000 0,0387989 0,07274421 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0387989 0,07268842 ! entry into host cell GO:0030260 34 12 0,000 0,0387989 0,07263272 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0387989 0,07257711 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0387989 0,07252158 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0387989 0,07246613 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0387989 0,07241077 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0387989 0,0723555 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0387989 0,07230031 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0387989 0,0722452 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0387989 0,07219018 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0387989 0,07213524 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0387989 0,07208038 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0387989 0,07202561 ! cranial nerve development GO:0021545 23 12 0,000 0,0387989 0,07197092 ! fucose catabolic process GO:0019317 25 12 0,000 0,0387989 0,07191631 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0387989 0,07186179 ! histone acetylation GO:0016573 27 12 0,000 0,0387989 0,07180735 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0387989 0,07175299 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0387989 0,07169872 ! zymogen activation GO:0031638 18 12 0,000 0,0387989 0,07164452 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0387989 0,07159041 ! T cell homeostasis GO:0043029 28 12 0,000 0,0387989 0,07153638 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0387989 0,07148243 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0387989 0,07142856 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0387989 0,07137478 ! oocyte differentiation GO:0009994 21 12 0,000 0,0387989 0,07132107 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0387989 0,07126744 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0387989 0,0712139 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,0387989 0,07116044 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0387989 0,07110705 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0387989 0,07105375 ! defense response to fungus GO:0050832 15 12 0,000 0,0387989 0,07100053 ! developmental induction GO:0031128 22 12 0,000 0,0387989 0,07094738 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0387989 0,07089432 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0387989 0,07084133 ! response to cold GO:0009409 17 12 0,000 0,0387989 0,07078843 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0387989 0,0707356 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0387989 0,07068285 ! leukocyte differentiation GO:0002521 232 98 1,000 0,04160508 0,07573861 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,04160508 0,07568221 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,04196394 0,07627821 ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04196394 0,0762215 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04196394 0,07616487 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04196394 0,07610833 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04196394 0,07605187 ! peroxisomal transport GO:0043574 28 13 0,000 0,04196394 0,07599549 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04196394 0,0759392 ! cartilage condensation GO:0001502 22 13 0,000 0,04196394 0,07588299 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04196394 0,07582686 ! organelle fusion GO:0048284 36 13 0,000 0,04196394 0,07577082 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04196394 0,07571486 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,04196394 0,07565898 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04196394 0,07560318 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04196394 0,07554747 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,04196394 0,07549184 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04196394 0,07543629 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04196394 0,07538082 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,04196394 0,07532543 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04196394 0,07527013 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04196394 0,07521491 ! methionine metabolic process GO:0006555 31 13 0,000 0,04196394 0,07515976 ! plasma membrane organization GO:0007009 27 13 0,000 0,04196394 0,0751047 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04196394 0,07504972 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04196394 0,07499482 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04196394 0,07494 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,04196394 0,07488526 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,04196394 0,0748306 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,04196394 0,07477602 ! exocrine system development GO:0035272 34 13 0,000 0,04196394 0,07472151 ! asymmetric protein localization GO:0008105 24 13 0,000 0,04196394 0,07466709 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,04196394 0,07461275 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,04196394 0,07455848 ! L-glutamate transport GO:0015813 30 13 0,000 0,04196394 0,0745043 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04196394 0,07445019 ! protein homotetramerization GO:0051289 24 13 0,000 0,04196394 0,07439617 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04196394 0,07434222 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04196394 0,07428835 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,04196394 0,07423455 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,04196394 0,07418084 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04196394 0,0741272 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04196394 0,07407364 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04196394 0,07402016 ! histone methylation GO:0016571 29 13 0,000 0,04196394 0,07396675 ! chromatin silencing GO:0006342 29 13 0,000 0,04196394 0,07391342 ! gland morphogenesis GO:0022612 31 13 0,000 0,04196394 0,07386017 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04196394 0,073807 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,04196394 0,0737539 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04196394 0,07370087 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,04196394 0,07364793 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,04196394 0,07359506 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,04196394 0,07354226 ! spleen development GO:0048536 24 13 0,000 0,04196394 0,07348955 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,04196394 0,0734369 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,04196394 0,07338434 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,04196394 0,07333184 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04196394 0,07327943 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04196394 0,07322708 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04196394 0,07317482 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04196394 0,07312262 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04196394 0,0730705 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04196394 0,07301846 ! insulin secretion GO:0030073 24 13 0,000 0,04196394 0,07296649 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04196394 0,07291459 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,04196394 0,07286277 ! acrosome reaction GO:0007340 19 13 0,000 0,04196394 0,07281102 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04196394 0,07275934 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,04196394 0,07270774 ! rRNA transcription GO:0009303 28 14 0,000 0,04511866 0,07811828 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04511866 0,07806295 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,04511866 0,07800771 ! water transport GO:0006833 21 14 0,000 0,04511866 0,07795254 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04511866 0,07789745 ! non-recombinational repair GO:0000726 29 14 0,000 0,04511866 0,07784244 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,04511866 0,0777875 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04511866 0,07773264 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,04511866 0,07767786 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04511866 0,07762316 ! lipid localization GO:0010876 32 14 0,000 0,04511866 0,07756853 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04511866 0,07751399 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04511866 0,07745951 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04511866 0,07740512 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04511866 0,0773508 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04511866 0,07729656 ! arginine metabolic process GO:0006525 21 14 0,000 0,04511866 0,07724239 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04511866 0,0771883 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,04511866 0,07713428 ! regulation of heart rate GO:0002027 25 14 0,000 0,04511866 0,07708034 ! fear response GO:0042596 34 14 0,000 0,04511866 0,07702648 ! organic alcohol transport GO:0015850 29 14 0,000 0,04511866 0,07697269 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04511866 0,07691897 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,04511866 0,07686533 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04511866 0,07681177 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04511866 0,07675828 ! bone mineralization GO:0030282 18 14 0,000 0,04511866 0,07670486 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04511866 0,07665152 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04511866 0,07659825 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,04511866 0,07654506 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04511866 0,07649194 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04511866 0,0764389 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,04511866 0,07638592 ! ribosome assembly GO:0042255 18 14 0,000 0,04511866 0,07633302 ! cerebellum development GO:0021549 23 14 0,000 0,04511866 0,0762802 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04511866 0,07622745 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04511866 0,07617477 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04511866 0,07612216 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04511866 0,07606963 ! NADP metabolic process GO:0006739 24 14 0,000 0,04511866 0,07601716 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04511866 0,07596477 ! oxygen transport GO:0015671 22 14 0,000 0,04511866 0,07591246 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04511866 0,07586021 ! male genitalia development GO:0030539 26 14 0,000 0,04511866 0,07580804 ! regulation of RNA stability GO:0043487 33 14 0,000 0,04511866 0,07575594 ! regulation of axon extension GO:0030516 43 14 0,000 0,04511866 0,07570391 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04511866 0,07565195 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,04511866 0,07560006 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04826308 0,08081336 ! lactation GO:0007595 30 15 0,000 0,04826308 0,08075801 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,04826308 0,08070274 ! reproductive cellular process GO:0048610 22 15 0,000 0,04826308 0,08064754 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04826308 0,08059241 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04826308 0,08053736 ! superoxide anion generation GO:0042554 22 15 0,000 0,04826308 0,08048239 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04826308 0,08042749 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,04826308 0,08037266 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04826308 0,08031791 ! copper ion transport GO:0006825 22 15 0,000 0,04826308 0,08026324 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04826308 0,08020864 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04826308 0,08015411 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04826308 0,08009966 ! sulfate transport GO:0008272 27 15 0,000 0,04826308 0,08004528 ! response to cAMP GO:0051591 25 15 0,000 0,04826308 0,07999098 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04826308 0,07993674 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04826308 0,07988259 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04826308 0,0798285 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04826308 0,07977449 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04826308 0,07972055 ! vesicle coating GO:0006901 38 15 0,000 0,04826308 0,07966669 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,04826308 0,07961289 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,04826308 0,07955918 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04826308 0,07950553 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04826308 0,07945195 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04826308 0,07939845 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04826308 0,07934502 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04826308 0,07929166 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04826308 0,07923837 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04826308 0,07918516 ! histone deacetylation GO:0016575 24 15 0,000 0,04826308 0,07913201 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04826308 0,07907894 ! water homeostasis GO:0030104 28 15 0,000 0,04826308 0,07902594 ! cofactor transport GO:0051181 30 15 0,000 0,04826308 0,07897301 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04826308 0,07892015 ! muscle maintenance GO:0046716 26 15 0,000 0,04826308 0,07886736 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04826308 0,07881464 ! intestinal absorption GO:0050892 31 15 0,000 0,04826308 0,07876199 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04826308 0,07870941 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04826308 0,0786569 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04826308 0,07860446 ! cell killing GO:0001906 32 15 0,000 0,04826308 0,0785521 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04826308 0,0784998 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04826308 0,07844757 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04826308 0,07839541 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04826308 0,07834332 ! actin filament polymerization GO:0030041 27 15 0,000 0,04826308 0,0782913 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04826308 0,07823935 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,05139723 0,08326487 ! positive regulation of cell size GO:0045793 29 16 0,000 0,05139723 0,08320969 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,05139723 0,08315459 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,05139723 0,08309955 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,05139723 0,08304459 ! bone remodeling GO:0046849 28 16 0,000 0,05139723 0,08298971 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,05139723 0,08293489 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05139723 0,08288015 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,05139723 0,08282548 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,05139723 0,08277088 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,05139723 0,08271635 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,05139723 0,0826619 ! startle response GO:0001964 28 16 0,000 0,05139723 0,08260752 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,05139723 0,08255321 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,05139723 0,08249897 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,05139723 0,0824448 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,05139723 0,0823907 ! protein polyubiquitination GO:0000209 41 16 0,000 0,05139723 0,08233667 ! glutamate metabolic process GO:0006536 25 16 0,000 0,05139723 0,08228272 ! pituitary gland development GO:0021983 30 16 0,000 0,05139723 0,08222883 ! response to osmotic stress GO:0006970 27 16 0,000 0,05139723 0,08217502 ! lysosomal transport GO:0007041 31 16 0,000 0,05139723 0,08212127 ! fructose metabolic process GO:0006000 25 16 0,000 0,05139723 0,0820676 ! L-amino acid transport GO:0015807 33 16 0,000 0,05139723 0,08201399 ! stem cell development GO:0048864 46 16 0,000 0,05139723 0,08196046 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05139723 0,081907 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05139723 0,0818536 ! intermediate filament-based process GO:0045103 36 16 0,000 0,05139723 0,08180028 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,05139723 0,08174702 ! negative regulation of immune response GO:0050777 38 16 0,000 0,05139723 0,08169384 ! axon cargo transport GO:0008088 46 16 0,000 0,05139723 0,08164072 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,05139723 0,08158767 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,05139723 0,08153469 ! DNA replication initiation GO:0006270 28 16 0,000 0,05139723 0,08148178 ! neuron recognition GO:0008038 40 16 0,000 0,05139723 0,08142894 ! mRNA splice site selection GO:0006376 44 16 0,000 0,05139723 0,08137617 ! tissue regeneration GO:0042246 27 16 0,000 0,05139723 0,08132346 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,05139723 0,08127083 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,05139723 0,08121826 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,05139723 0,08116576 ! biomineral formation GO:0031214 22 16 0,000 0,05139723 0,08111332 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,05139723 0,08106096 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,05139723 0,08100866 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,05139723 0,08095643 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05139723 0,08090427 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,05139723 0,08085217 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,05139723 0,08080015 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,05139723 0,08074818 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,05139723 0,08069629 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,05139723 0,08064446 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,05452114 0,08549111 ! metencephalon development GO:0022037 32 17 0,000 0,05452114 0,08543628 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,05452114 0,08538151 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,05452114 0,08532681 ! signal complex assembly GO:0007172 47 17 0,000 0,05452114 0,08527219 ! filopodium assembly GO:0046847 42 17 0,000 0,05452114 0,08521763 ! gene silencing by RNA GO:0031047 38 17 0,000 0,05452114 0,08516314 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,05452114 0,08510873 ! glial cell development GO:0021782 28 17 0,000 0,05452114 0,08505438 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,05452114 0,0850001 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,05452114 0,08494589 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,05452114 0,08489175 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,05452114 0,08483768 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,05452114 0,08478368 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,05452114 0,08472974 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,05452114 0,08467588 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,05452114 0,08462208 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,05452114 0,08456835 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,05452114 0,08451469 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,05452114 0,0844611 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,05452114 0,08440758 ! membrane budding GO:0006900 42 17 0,000 0,05452114 0,08435412 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,05452114 0,08430073 ! regulation of protein binding GO:0043393 33 17 0,000 0,05452114 0,08424741 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,05452114 0,08419416 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,05452114 0,08414097 ! genitalia development GO:0048806 32 17 0,000 0,05452114 0,08408785 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,05452114 0,0840348 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,05452114 0,08398181 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,05452114 0,08392889 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,05452114 0,08387604 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,05452114 0,08382326 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,05452114 0,08377054 ! steroid catabolic process GO:0006706 34 17 0,000 0,05452114 0,08371789 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,05452114 0,0836653 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,05452114 0,08361278 ! gas transport GO:0015669 26 17 0,000 0,05452114 0,08356032 ! organic cation transport GO:0015695 32 17 0,000 0,05452114 0,08350793 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,05452114 0,08345561 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,05452114 0,08340335 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,05452114 0,08335116 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,05763486 0,08805626 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,05763486 0,08800123 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,05763486 0,08794626 ! limbic system development GO:0021761 40 18 0,000 0,05763486 0,08789136 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05763486 0,08783654 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,05763486 0,08778177 ! adult walking behavior GO:0007628 36 18 0,000 0,05763486 0,08772708 ! patterning of blood vessels GO:0001569 43 18 0,000 0,05763486 0,08767246 ! heart looping GO:0001947 34 18 0,000 0,05763486 0,0876179 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,05763486 0,08756341 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,05763486 0,08750899 ! centrosome cycle GO:0007098 26 18 0,000 0,05763486 0,08745464 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,05763486 0,08740035 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,05763486 0,08734613 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,05763486 0,08729198 ! glycine metabolic process GO:0006544 30 18 0,000 0,05763486 0,0872379 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05763486 0,08718388 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,05763486 0,08712993 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,05763486 0,08707605 ! DNA integration GO:0015074 32 18 0,000 0,05763486 0,08702223 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,05763486 0,08696848 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,05763486 0,08691479 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,05763486 0,08686118 ! neural crest cell migration GO:0001755 41 18 0,000 0,05763486 0,08680762 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,05763486 0,08675414 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,05763486 0,08670072 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,05763486 0,08664736 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,05763486 0,08659408 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,05763486 0,08654085 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,05763486 0,08648769 ! detection of bacterium GO:0016045 22 18 0,000 0,05763486 0,0864346 ! nerve development GO:0021675 34 18 0,000 0,05763486 0,08638157 ! defense response to virus GO:0051607 43 18 0,000 0,05763486 0,08632861 ! microspike assembly GO:0030035 46 18 0,000 0,05763486 0,08627571 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,05763486 0,08622288 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,05763486 0,08617011 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,06073841 0,0907547 ! positive regulation of translation GO:0045727 31 19 0,000 0,06073841 0,09069923 ! negative regulation of defense response GO:0031348 27 19 0,000 0,06073841 0,09064382 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,06073841 0,09058849 ! neuron maturation GO:0042551 46 19 0,000 0,06073841 0,09053321 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,06073841 0,09047801 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,06073841 0,09042288 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,06073841 0,09036781 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,06073841 0,09031281 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06073841 0,09025787 ! memory GO:0007613 34 19 0,000 0,06073841 0,090203 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,06073841 0,0901482 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,06073841 0,09009347 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,06073841 0,0900388 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,06073841 0,0899842 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,06073841 0,08992966 ! cerebral cortex development GO:0021987 40 19 0,000 0,06073841 0,08987519 ! pigmentation during development GO:0048066 42 19 0,000 0,06073841 0,08982079 ! heme metabolic process GO:0042168 40 19 0,000 0,06073841 0,08976645 ! neuromuscular junction development GO:0007528 43 19 0,000 0,06073841 0,08971218 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,06073841 0,08965797 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,06073841 0,08960383 ! response to fungus GO:0009620 26 19 0,000 0,06073841 0,08954975 ! peptide cross-linking GO:0018149 39 19 0,000 0,06073841 0,08949574 ! protein export from nucleus GO:0006611 40 19 0,000 0,06073841 0,0894418 ! heart process GO:0003015 32 19 0,000 0,06073841 0,08938792 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,06073841 0,0893341 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,06073841 0,08928035 ! visual learning GO:0008542 38 19 0,000 0,06073841 0,08922666 ! cellular pigmentation GO:0033059 37 19 0,000 0,06073841 0,08917304 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,06073841 0,08911948 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,06073841 0,08906599 ! vitamin transport GO:0051180 31 19 0,000 0,06073841 0,08901256 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,06073841 0,0889592 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,06073841 0,0889059 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,06073841 0,08885266 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,06073841 0,08879948 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,06073841 0,08874638 ! cilium assembly GO:0042384 38 19 0,000 0,06073841 0,08869333 ! peptide hormone secretion GO:0030072 32 19 0,000 0,06073841 0,08864035 ! protein secretion GO:0009306 45 20 0,000 0,06383183 0,0930992 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,06383183 0,09304365 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,06383183 0,09298817 ! positive regulation of ossification GO:0045778 50 20 0,000 0,06383183 0,09293275 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,06383183 0,0928774 ! skin development GO:0043588 42 20 0,000 0,06383183 0,09282212 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,06383183 0,0927669 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,06383183 0,09271174 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,06383183 0,09265666 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,06383183 0,09260164 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,06383183 0,09254668 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,06383183 0,09249179 ! bile acid metabolic process GO:0008206 34 20 0,000 0,06383183 0,09243696 ! response to alkaloid GO:0043279 38 20 0,000 0,06383183 0,0923822 ! retinoid metabolic process GO:0001523 34 20 0,000 0,06383183 0,0923275 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,06383183 0,09227287 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,06383183 0,09221831 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,06383183 0,0921638 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,06383183 0,09210936 ! body fluid secretion GO:0007589 33 20 0,000 0,06383183 0,09205499 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,06383183 0,09200068 ! peptide secretion GO:0002790 38 20 0,000 0,06383183 0,09194644 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,06383183 0,09189225 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,06383183 0,09183814 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,06383183 0,09178408 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,06383183 0,09173009 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,06383183 0,09167616 ! cell-cell junction organization GO:0045216 43 20 0,000 0,06383183 0,0916223 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,06383183 0,0915685 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,06383183 0,09151476 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,06383183 0,09146109 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,06383183 0,09140748 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,06383183 0,09135393 ! regulation of glucose import GO:0046324 30 20 0,000 0,06383183 0,09130044 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,06383183 0,09124702 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,06383183 0,09119366 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,06383183 0,09114036 ! negative regulation of translation GO:0017148 32 20 0,000 0,06383183 0,09108712 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,06383183 0,09103395 ! regulation of cell killing GO:0031341 46 21 0,000 0,06691514 0,09537555 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,06691514 0,09531994 ! hormone secretion GO:0046879 39 21 0,000 0,06691514 0,09526439 ! cAMP metabolic process GO:0046058 41 21 0,000 0,06691514 0,09520891 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,06691514 0,09515349 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,06691514 0,09509813 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,06691514 0,09504284 ! ovarian follicle development GO:0001541 39 21 0,000 0,06691514 0,09498762 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,06691514 0,09493246 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,06691514 0,09487736 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,06691514 0,09482233 ! plasma membrane fusion GO:0045026 33 21 0,000 0,06691514 0,09476736 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,06691514 0,09471245 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,06691514 0,09465761 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,06691514 0,09460283 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,06691514 0,09454812 ! diencephalon development GO:0021536 36 21 0,000 0,06691514 0,09449346 ! collagen fibril organization GO:0030199 62 21 0,000 0,06691514 0,09443888 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,06691514 0,09438435 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,06691514 0,09432989 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,06691514 0,09427549 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,06691514 0,09422115 ! collagen catabolic process GO:0030574 29 21 0,000 0,06691514 0,09416687 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,06691514 0,09411266 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,06691514 0,09405851 ! sperm-egg recognition GO:0035036 23 21 0,000 0,06691514 0,09400442 ! actin filament-based movement GO:0030048 47 21 0,000 0,06691514 0,0939504 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,06998839 0,09820886 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,06998839 0,09815249 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,06998839 0,09809618 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,06998839 0,09803993 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,06998839 0,09798374 ! microtubule-based transport GO:0010970 59 22 0,000 0,06998839 0,09792763 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,06998839 0,09787157 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,06998839 0,09781558 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,06998839 0,09775965 ! vacuolar transport GO:0007034 41 22 0,000 0,06998839 0,09770379 ! central nervous system neuron development GO:0021954 47 22 0,000 0,06998839 0,09764799 ! fucose metabolic process GO:0006004 44 22 0,000 0,06998839 0,09759226 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,06998839 0,09753659 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,06998839 0,09748098 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,06998839 0,09742543 ! ureteric bud development GO:0001657 50 22 0,000 0,06998839 0,09736995 ! stem cell differentiation GO:0048863 57 22 0,000 0,06998839 0,09731453 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,06998839 0,09725918 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,06998839 0,09720388 ! cytolysis GO:0019835 27 22 0,000 0,06998839 0,09714866 ! renal system process GO:0003014 42 22 0,000 0,06998839 0,09709349 ! vasodilation GO:0042311 40 22 0,000 0,06998839 0,09703838 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,06998839 0,09698334 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,06998839 0,09692836 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,06998839 0,09687345 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,06998839 0,09681859 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,06998839 0,0967638 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,06998839 0,09670907 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,06998839 0,0966544 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,06998839 0,09659979 ! sarcomere organization GO:0045214 32 22 0,000 0,06998839 0,09654525 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,06998839 0,09649076 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,06998839 0,09643634 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,06998839 0,09638198 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,06998839 0,09632768 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,06998839 0,09627344 ! gut development GO:0048565 44 22 0,000 0,06998839 0,09621926 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,06998839 0,09616515 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,06998839 0,09611109 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,06998839 0,0960571 ! protein stabilization GO:0050821 41 22 0,000 0,06998839 0,09600316 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,0730516 0,10014874 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,0730516 0,10009257 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,0730516 0,10003647 ! gluconeogenesis GO:0006094 38 23 0,000 0,0730516 0,09998042 ! glycerol metabolic process GO:0006071 40 23 0,000 0,0730516 0,09992444 ! viral genome replication GO:0019079 44 23 0,000 0,0730516 0,09986853 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,0730516 0,09981267 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,0730516 0,09975688 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,0730516 0,09970115 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,0730516 0,09964548 ! regeneration GO:0031099 42 23 0,000 0,0730516 0,09958988 ! axis specification GO:0009798 43 23 0,000 0,0730516 0,09953433 ! visual behavior GO:0007632 46 23 0,000 0,0730516 0,09947885 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,0730516 0,09942343 ! response to ethanol GO:0045471 47 23 0,000 0,0730516 0,09936807 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,0730516 0,09931277 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,0730516 0,09925754 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,0730516 0,09920237 ! peroxisome organization GO:0007031 43 23 0,000 0,0730516 0,09914725 ! lysosome organization GO:0007040 47 23 0,000 0,0730516 0,0990922 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,0730516 0,09903721 ! vesicle targeting GO:0006903 49 23 0,000 0,0730516 0,09898228 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,0730516 0,09892741 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,0730516 0,09887261 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,0730516 0,09881786 ! DNA modification GO:0006304 36 23 0,000 0,0730516 0,09876317 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,0730516 0,09870855 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,0730516 0,09865398 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,0730516 0,09859948 ! hormone transport GO:0009914 41 23 0,000 0,0730516 0,09854503 ! cell-cell recognition GO:0009988 28 23 0,000 0,0730516 0,09849065 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,0730516 0,09843632 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,0730516 0,09838206 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,0730516 0,09832785 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,07610481 0,10238108 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,07610481 0,10232473 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,07610481 0,10226845 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,07610481 0,10221223 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,07610481 0,10215607 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,07610481 0,10209997 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,07610481 0,10204393 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,07610481 0,10198795 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,07610481 0,10193204 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,07610481 0,10187619 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,07610481 0,10182039 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,07610481 0,10176466 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,07610481 0,10170899 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,07610481 0,10165338 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,07610481 0,10159784 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,07610481 0,10154235 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,07610481 0,10148692 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,07610481 0,10143156 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,07610481 0,10137625 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,07610481 0,101321 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,07610481 0,10126582 ! membrane depolarization GO:0051899 45 24 0,000 0,07610481 0,10121069 ! pallium development GO:0021543 56 24 0,000 0,07610481 0,10115563 ! oogenesis GO:0048477 44 24 0,000 0,07610481 0,10110062 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,07610481 0,10104567 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,07610481 0,10099079 ! platelet activation GO:0030168 41 24 0,000 0,07610481 0,10093596 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,07610481 0,10088119 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,07610481 0,10082649 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,07610481 0,10077184 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,07610481 0,10071725 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,07610481 0,10066272 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,07610481 0,10060825 ! regulation of amine transport GO:0051952 41 24 0,000 0,07610481 0,10055384 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,07610481 0,10049948 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,07914804 0,10446173 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,07914804 0,10440533 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,07914804 0,10434898 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,07914804 0,1042927 ! leukocyte adhesion GO:0007159 55 25 0,000 0,07914804 0,10423648 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,07914804 0,10418032 ! phototransduction GO:0007602 37 25 0,000 0,07914804 0,10412421 ! vasculogenesis GO:0001570 49 25 0,000 0,07914804 0,10406817 ! vacuole organization GO:0007033 49 25 0,000 0,07914804 0,10401219 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,07914804 0,10395627 ! receptor metabolic process GO:0043112 53 25 0,000 0,07914804 0,10390041 ! chromosome condensation GO:0030261 48 25 0,000 0,07914804 0,10384461 ! regulation of behavior GO:0050795 48 25 0,000 0,07914804 0,10378887 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,07914804 0,10373319 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,07914804 0,10367757 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,07914804 0,10362201 ! immunoglobulin production GO:0002377 62 25 0,000 0,07914804 0,10356651 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,07914804 0,10351106 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,07914804 0,10345568 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,07914804 0,10340036 ! liver development GO:0001889 55 25 0,000 0,07914804 0,10334509 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,08218134 0,1072484 ! myelination GO:0042552 50 26 0,000 0,08218134 0,10719114 ! initiation of viral infection GO:0019059 60 26 0,000 0,08218134 0,10713394 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,08218134 0,10707681 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,08218134 0,10701973 ! molting cycle process GO:0022404 52 26 0,000 0,08218134 0,10696271 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,08218134 0,10690576 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,08218134 0,10684886 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,08218134 0,10679203 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,08218134 0,10673525 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,08218134 0,10667854 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,08218134 0,10662189 ! digestive system process GO:0022600 49 26 0,000 0,08218134 0,10656529 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,08218134 0,10650876 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,08218134 0,10645229 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,08218134 0,10639587 ! osteoblast differentiation GO:0001649 63 26 0,000 0,08218134 0,10633952 ! neural crest cell development GO:0014032 59 26 0,000 0,08218134 0,10628322 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,08218134 0,10622699 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,08218134 0,10617081 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,08218134 0,1061147 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,08218134 0,10605864 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,08218134 0,10600265 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,08218134 0,10594671 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,08218134 0,10589083 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,08218134 0,10583501 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,08218134 0,10577925 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,08218134 0,10572354 ! blastocyst development GO:0001824 50 26 0,000 0,08218134 0,1056679 ! telomere organization GO:0032200 46 26 0,000 0,08218134 0,10561232 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,08218134 0,10555679 ! neural tube closure GO:0001843 58 26 0,000 0,08218134 0,10550132 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,08218134 0,10544591 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,08218134 0,10539056 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,08218134 0,10533526 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,08520473 0,1091532 ! embryonic pattern specification GO:0009880 49 27 0,000 0,08520473 0,10909599 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,08520473 0,10903884 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,08520473 0,10898176 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,08520473 0,10892473 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,08520473 0,10886776 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,08520473 0,10881085 ! iron ion transport GO:0006826 65 27 0,000 0,08520473 0,108754 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,08520473 0,10869721 ! superoxide metabolic process GO:0006801 41 27 0,000 0,08520473 0,10864048 ! tube lumen formation GO:0035148 59 27 0,000 0,08520473 0,1085838 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,08520473 0,10852719 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,08520473 0,10847064 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,08520473 0,10841414 ! response to toxin GO:0009636 49 27 0,000 0,08520473 0,10835771 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,08520473 0,10830133 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,08520473 0,10824501 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,08520473 0,10818875 ! leukocyte proliferation GO:0070661 59 27 0,000 0,08520473 0,10813255 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,08520473 0,1080764 ! neuron fate commitment GO:0048663 52 28 0,000 0,08821825 0,11184077 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,08821825 0,11178277 ! protein amino acid acylation GO:0043543 59 28 0,000 0,08821825 0,11172482 ! vesicle docking GO:0048278 55 28 0,000 0,08821825 0,11166693 ! circadian rhythm GO:0007623 56 28 0,000 0,08821825 0,1116091 ! dendrite development GO:0016358 67 28 0,000 0,08821825 0,11155133 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,08821825 0,11149362 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,08821825 0,11143597 ! sperm motility GO:0030317 37 28 0,000 0,08821825 0,11137838 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,08821825 0,11132085 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,08821825 0,11126338 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,08821825 0,11120597 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,08821825 0,11114862 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,08821825 0,11109133 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,08821825 0,11103409 ! glutathione metabolic process GO:0006749 42 28 0,000 0,08821825 0,11097692 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,08821825 0,1109198 ! lipid oxidation GO:0034440 48 28 0,000 0,08821825 0,11086274 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,08821825 0,11080574 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,08821825 0,1107488 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,09122192 0,11446078 ! translational initiation GO:0006413 66 29 0,000 0,09122192 0,11440203 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,09122192 0,11434333 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,09122192 0,11428469 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,09122192 0,11422611 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,09122192 0,1141676 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,09122192 0,11410914 ! primary neural tube formation GO:0014020 61 29 0,000 0,09122192 0,11405074 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,09122192 0,1139924 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,09122192 0,11393412 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,09122192 0,11387591 ! somitogenesis GO:0001756 52 29 0,000 0,09122192 0,11381775 ! synaptogenesis GO:0007416 46 29 0,000 0,09122192 0,11375965 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,09122192 0,11370161 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,09122192 0,11364362 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,09122192 0,1135857 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,09122192 0,11352784 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,09421578 0,11719407 ! phenol metabolic process GO:0018958 56 30 0,000 0,09421578 0,11713443 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,09421578 0,11707485 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,09421578 0,11701533 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,09421578 0,11695587 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,09421578 0,11689647 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,09421578 0,11683713 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,09421578 0,11677786 ! acute-phase response GO:0006953 50 30 0,000 0,09421578 0,11671864 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,09421578 0,11665948 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,09421578 0,11660038 ! myofibril assembly GO:0030239 50 30 0,000 0,09421578 0,11654134 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,09421578 0,11648237 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,09421578 0,11642345 ! cell fate determination GO:0001709 64 30 0,000 0,09421578 0,11636459 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,09421578 0,11630579 ! phospholipid transport GO:0015914 65 30 0,000 0,09421578 0,11624705 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,09421578 0,11618837 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,09421578 0,11612974 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,09421578 0,11607118 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,09421578 0,11601268 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 0,000 0,09421578 0,11595423 ! regulation of coagulation GO:0050818 52 30 0,000 0,09421578 0,11589585 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,09719987 0,11950643 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,09719987 0,11944631 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,09719987 0,11938626 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,09719987 0,11932627 ! cell junction assembly GO:0034329 85 31 0,000 0,09719987 0,11926633 ! regulation of innate immune response GO:0045088 57 31 0,000 0,09719987 0,11920646 ! ovulation cycle process GO:0022602 55 31 0,000 0,09719987 0,11914665 ! peptide transport GO:0015833 60 31 0,000 0,09719987 0,1190869 ! male gonad development GO:0008584 56 31 0,000 0,09719987 0,1190272 ! iron ion homeostasis GO:0055072 60 31 0,000 0,09719987 0,11896757 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,09719987 0,118908 ! detection of light stimulus GO:0009583 44 31 0,000 0,09719987 0,11884848 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,09719987 0,11878903 ! natural killer cell activation GO:0030101 50 31 0,000 0,09719987 0,11872964 ! ensheathment of neurons GO:0007272 64 31 0,000 0,09719987 0,1186703 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,09719987 0,11861102 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,09719987 0,11855181 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,09719987 0,11849265 ! eye morphogenesis GO:0048592 65 31 0,000 0,09719987 0,11843355 ! response to heat GO:0009408 54 31 0,000 0,09719987 0,11837451 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,09719987 0,11831553 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,1001742 0,12187529 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,1001742 0,12181462 ! collagen metabolic process GO:0032963 49 32 0,000 0,1001742 0,12175402 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,1001742 0,12169347 ! spindle organization GO:0007051 50 32 0,000 0,1001742 0,12163299 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,1001742 0,12157257 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,1001742 0,1215122 ! metanephros development GO:0001656 81 32 0,000 0,1001742 0,1214519 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,1001742 0,12139165 ! muscle cell development GO:0055001 52 32 0,000 0,1001742 0,12133147 ! mesoderm formation GO:0001707 73 32 0,000 0,1001742 0,12127135 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,1001742 0,12121128 ! ovulation cycle GO:0042698 57 32 0,000 0,1001742 0,12115127 ! peripheral nervous system development GO:0007422 68 32 0,000 0,1001742 0,12109133 ! BMP signaling pathway GO:0030509 71 32 0,000 0,1001742 0,12103144 ! hindbrain development GO:0030902 65 32 0,000 0,1001742 0,12097161 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,1001742 0,12091185 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,1001742 0,12085214 ! gene silencing GO:0016458 71 32 0,000 0,1001742 0,12079249 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,10313882 0,12430594 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,10313882 0,12424465 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,10313882 0,12418341 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,10313882 0,12412224 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,10313882 0,12406112 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,10313882 0,12400007 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,10313882 0,12393908 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,10313882 0,12387814 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,10313882 0,12381727 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,10313882 0,12375646 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,10609376 0,12723959 ! glial cell differentiation GO:0010001 67 34 0,000 0,10609376 0,12717716 ! post-embryonic development GO:0009791 76 34 0,000 0,10609376 0,12711479 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,10609376 0,12705248 ! cholesterol transport GO:0030301 62 34 0,000 0,10609376 0,12699023 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,10609376 0,12692804 ! spliceosome assembly GO:0000245 75 34 0,000 0,10609376 0,12686591 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,10609376 0,12680384 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,10609376 0,12674184 ! formation of primary germ layer GO:0001704 76 34 0,000 0,10609376 0,12667989 ! cell fate specification GO:0001708 56 34 0,000 0,10609376 0,126618 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,10609376 0,12655618 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,10609376 0,12649441 ! adult locomotory behavior GO:0008344 62 34 0,000 0,10609376 0,12643271 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,10903904 0,12987927 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,10903904 0,12981598 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,10903904 0,12975274 ! membrane docking GO:0022406 69 35 0,000 0,10903904 0,12968957 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,10903904 0,12962646 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,10903904 0,12956342 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,10903904 0,12950043 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,10903904 0,1294375 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,10903904 0,12937464 ! ceramide metabolic process GO:0006672 72 35 0,000 0,10903904 0,12931184 ! telencephalon development GO:0021537 81 35 0,000 0,10903904 0,12924909 ! sterol transport GO:0015918 63 35 0,000 0,10903904 0,12918641 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,10903904 0,12912379 ! placenta development GO:0001890 53 35 0,000 0,10903904 0,12906123 ! vesicle localization GO:0051648 70 35 0,000 0,10903904 0,12899873 ! regulation of muscle development GO:0048634 82 36 0,000 0,11197471 0,13240765 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,11197471 0,13234359 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,11197471 0,1322796 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,11197471 0,13221566 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,11197471 0,13215179 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,11197471 0,13208798 ! positive regulation of cell development GO:0010720 85 36 0,000 0,11197471 0,13202423 ! protein targeting to membrane GO:0006612 75 36 0,000 0,11197471 0,13196054 ! regulation of proteolysis GO:0030162 77 36 0,000 0,11197471 0,13189692 ! aerobic respiration GO:0009060 56 36 0,000 0,11197471 0,13183335 ! cytokine production GO:0001816 68 36 0,000 0,11197471 0,13176985 ! embryonic organ development GO:0048568 67 36 0,000 0,11197471 0,13170641 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,11197471 0,13164303 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,11197471 0,1315797 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,11490078 0,13495317 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,11490078 0,13488832 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,11490078 0,13482353 ! sister chromatid segregation GO:0000819 65 37 0,000 0,11490078 0,13475881 ! odontogenesis GO:0042476 74 37 0,000 0,11490078 0,13469415 ! actomyosin structure organization GO:0031032 68 37 0,000 0,11490078 0,13462954 ! cell junction organization GO:0034330 96 37 0,000 0,11490078 0,134565 ! tissue remodeling GO:0048771 78 37 0,000 0,11490078 0,13450053 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,11490078 0,13443611 ! female gonad development GO:0008585 71 37 0,000 0,11490078 0,13437176 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,11490078 0,13430746 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,11490078 0,13424323 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,11490078 0,13417906 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,11781729 0,13751918 ! meiosis I GO:0007127 74 38 0,000 0,11781729 0,13745351 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,11781729 0,13738789 ! organic anion transport GO:0015711 82 38 0,000 0,11781729 0,13732235 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,11781729 0,13725686 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,11781729 0,13719144 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,11781729 0,13712608 ! spermatid development GO:0007286 69 38 0,000 0,11781729 0,13706078 ! pigment metabolic process GO:0042440 87 38 0,000 0,11781729 0,13699554 ! neural tube formation GO:0001841 79 38 0,000 0,11781729 0,13693037 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,12072427 0,14024223 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,12072427 0,14017557 ! negative regulation of binding GO:0051100 71 39 0,000 0,12072427 0,14010898 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,12072427 0,14004245 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,12072427 0,13997599 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,12072427 0,13990958 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,12072427 0,13984324 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,12072427 0,13977697 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,12072427 0,13971075 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,12362176 0,14299619 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,12362176 0,14292852 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,12362176 0,14286091 ! learning GO:0007612 82 40 0,000 0,12362176 0,14279336 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,12362176 0,14272588 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,12362176 0,14265846 ! lipid homeostasis GO:0055088 75 40 0,000 0,12362176 0,14259111 ! mismatch repair GO:0006298 58 40 0,000 0,12362176 0,14252381 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,12362176 0,14245659 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,12362176 0,14238942 ! RNA export from nucleus GO:0006405 61 41 0,000 0,12650978 0,14564722 ! mRNA catabolic process GO:0006402 79 41 0,000 0,12650978 0,14557861 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,12650978 0,14551007 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,12650978 0,1454416 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,12650978 0,14537319 ! gliogenesis GO:0042063 91 41 0,000 0,12650978 0,14530484 ! feeding behavior GO:0007631 69 41 0,000 0,12650978 0,14523656 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,12650978 0,14516834 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,12650978 0,14510018 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,12650978 0,14503209 ! spermatid differentiation GO:0048515 73 41 0,000 0,12650978 0,14496407 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,12650978 0,14489611 ! RNA modification GO:0009451 64 41 0,000 0,12650978 0,14482821 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,12938836 0,14805423 ! ear morphogenesis GO:0042471 64 42 0,000 0,12938836 0,14798491 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,12938836 0,14791566 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,12938836 0,14784648 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,12938836 0,14777736 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,12938836 0,14770831 ! regulation of protein secretion GO:0050708 77 42 0,000 0,12938836 0,14763932 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,12938836 0,14757039 ! cytokinesis GO:0000910 84 42 0,000 0,12938836 0,14750153 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,12938836 0,14743273 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,13225754 0,15063178 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,13225754 0,15056159 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,13225754 0,15049147 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,13225754 0,1504214 ! regulation of tube size GO:0035150 76 43 0,000 0,13225754 0,15035141 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,13225754 0,15028148 ! glucose transport GO:0015758 66 43 0,000 0,13225754 0,15021161 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,13225754 0,15014181 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,13225754 0,15007207 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,13225754 0,1500024 ! segmentation GO:0035282 78 43 0,000 0,13225754 0,1499328 ! ion transmembrane transport GO:0034220 79 43 0,000 0,13225754 0,14986325 ! neuron migration GO:0001764 85 43 0,000 0,13225754 0,14979378 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,13225754 0,14972436 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,13511735 0,152891 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,13511735 0,15282022 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,13511735 0,1527495 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,13511735 0,15267885 ! hexose transport GO:0008645 68 44 0,000 0,13511735 0,15260826 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,13511735 0,15253774 ! phagocytosis GO:0006909 105 44 0,000 0,13511735 0,15246729 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,13511735 0,1523969 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,1379678 0,15554008 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,1379678 0,15546833 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,1379678 0,15539665 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,1379678 0,15532504 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,1379678 0,1552535 ! female gamete generation GO:0007292 71 45 0,000 0,1379678 0,15518202 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,1379678 0,1551106 ! developmental growth GO:0048589 88 45 0,000 0,1379678 0,15503926 ! maintenance of location in cell GO:0051651 101 45 0,000 0,1379678 0,15496797 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,14080895 0,15808652 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,14080895 0,1580139 ! glycolysis GO:0006096 71 46 0,000 0,14080895 0,15794135 ! leukocyte migration GO:0050900 75 46 0,000 0,14080895 0,15786887 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,14080895 0,15779645 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,14080895 0,1577241 ! pigmentation GO:0043473 103 46 0,000 0,14080895 0,15765181 ! cell growth GO:0016049 90 46 0,000 0,14080895 0,1575796 ! neural tube development GO:0021915 91 47 0,000 0,14364081 0,16067513 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,14364081 0,1606016 ! positive regulation of defense response GO:0031349 88 48 0,000 0,14646341 0,16368258 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,14646341 0,16360774 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,14646341 0,16353296 ! cellular component disassembly GO:0022411 89 48 0,000 0,14646341 0,16345825 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,14646341 0,16338362 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,14646341 0,16330904 ! male sex differentiation GO:0046661 93 48 0,000 0,14646341 0,16323454 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,14646341 0,16316011 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,14646341 0,16308574 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,14646341 0,16301144 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,14646341 0,16293721 ! methylation GO:0032259 97 48 0,000 0,14646341 0,16286305 ! response to calcium ion GO:0051592 94 49 0,000 0,14927679 0,16591593 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,14927679 0,16584048 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,14927679 0,16576509 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,14927679 0,16568978 ! JNK cascade GO:0007254 106 49 0,000 0,14927679 0,16561454 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,14927679 0,16553936 ! regulation of action potential GO:0001508 102 50 0,000 0,15208098 0,16857252 ! regulation of ion transport GO:0043269 86 50 0,000 0,15208098 0,16849607 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,15208098 0,16841969 ! endocrine system development GO:0035270 109 50 0,000 0,15208098 0,16834338 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,15208098 0,16826714 ! regulation of ossification GO:0030278 123 50 0,000 0,15208098 0,16819096 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,15208098 0,16811486 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,15208098 0,16803882 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,15208098 0,16796286 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,15208098 0,16788696 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,154876 0,17089525 ! viral infectious cycle GO:0019058 104 51 0,000 0,154876 0,17081809 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,154876 0,17074101 ! peptide metabolic process GO:0006518 80 51 0,000 0,154876 0,17066399 ! response to temperature stimulus GO:0009266 84 51 0,000 0,154876 0,17058705 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,154876 0,17051017 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,154876 0,17043337 ! positive regulation of binding GO:0051099 88 52 0,000 0,15766189 0,17342098 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,15766189 0,17334293 ! Notch signaling pathway GO:0007219 111 52 0,000 0,15766189 0,17326496 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,15766189 0,17318705 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,15766189 0,17310921 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,15766189 0,17303145 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,15766189 0,17295375 ! excretion GO:0007588 87 52 0,000 0,15766189 0,17287612 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,15766189 0,17279856 ! histone modification GO:0016570 104 52 0,000 0,15766189 0,17272108 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,15766189 0,17264366 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,15766189 0,17256631 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,16043867 0,17552695 ! inner ear development GO:0048839 89 53 0,000 0,16043867 0,17544838 ! chromatin remodeling GO:0006338 122 53 0,000 0,16043867 0,17536988 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,16043867 0,17529145 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,16043867 0,17521309 ! vesicle organization GO:0016050 127 53 0,000 0,16043867 0,1751348 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,16043867 0,17505658 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,16043867 0,17497843 ! synapse organization GO:0050808 102 53 0,000 0,16043867 0,17490035 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,16320638 0,17783817 ! regulation of translational initiation GO:0006446 87 54 0,000 0,16320638 0,17775889 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,16320638 0,17767967 ! neuromuscular process GO:0050905 107 54 0,000 0,16320638 0,17760053 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,16320638 0,17752145 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,16320638 0,17744245 ! membrane fusion GO:0006944 122 54 0,000 0,16320638 0,17736352 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,16320638 0,17728465 ! covalent chromatin modification GO:0016569 115 54 0,000 0,16320638 0,17720586 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,16320638 0,17712714 ! regulation of cell shape GO:0008360 142 54 0,000 0,16320638 0,17704848 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,16320638 0,1769699 ! RNA catabolic process GO:0006401 103 55 0,000 0,16596504 0,17988136 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,16596504 0,17980159 ! cell recognition GO:0008037 98 55 0,000 0,16596504 0,17972189 ! cell maturation GO:0048469 107 55 0,000 0,16596504 0,17964227 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,16596504 0,17956271 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,16871468 0,18245683 ! glucose catabolic process GO:0006007 88 56 0,000 0,16871468 0,18237609 ! chloride transport GO:0006821 102 57 0,000 0,17145534 0,1852567 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,17145534 0,1851748 ! regulation of actin filament length GO:0030832 118 58 0,000 0,17418704 0,18804195 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,17418704 0,18795889 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,17418704 0,18787591 ! gastrulation GO:0007369 122 58 0,000 0,17418704 0,187793 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,17418704 0,18771016 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,17418704 0,18762739 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,17418704 0,1875447 ! maintenance of location GO:0051235 124 58 0,000 0,17418704 0,18746208 ! nuclear export GO:0051168 110 59 0,000 0,1769098 0,19030852 ! establishment of organelle localization GO:0051656 122 59 0,000 0,1769098 0,19022476 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,17962367 0,19305791 ! DNA catabolic process GO:0006308 94 60 0,000 0,17962367 0,19297301 ! regulation of endocytosis GO:0030100 104 60 0,000 0,17962367 0,19288819 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,17962367 0,19280344 ! adult behavior GO:0030534 104 60 0,000 0,17962367 0,19271876 ! kidney development GO:0001822 133 60 0,000 0,17962367 0,19263416 ! regulation of cellular component size GO:0032535 125 61 0,000 0,18232866 0,19544929 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,18232866 0,19536356 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,18232866 0,19527792 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,18232866 0,19519234 ! regulation of heart contraction GO:0008016 123 61 0,000 0,18232866 0,19510684 ! camera-type eye development GO:0043010 126 61 0,000 0,18232866 0,19502142 ! proton transport GO:0015992 117 61 0,000 0,18232866 0,19493607 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,18232866 0,1948508 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,18502482 0,19764566 ! tRNA processing GO:0008033 102 62 0,000 0,18502482 0,19755928 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,18502482 0,19747297 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,18771215 0,20025362 ! regulation of mitosis GO:0007088 112 63 0,000 0,18771215 0,20016621 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,18771215 0,20007888 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,18771215 0,19999162 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,18771215 0,19990444 ! hydrogen transport GO:0006818 121 64 0,000 0,1903907 0,20266862 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,1903907 0,20258035 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,1903907 0,20249216 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,1930605 0,2052423 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,1930605 0,20515302 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,1930605 0,20506382 ! ear development GO:0043583 114 66 0,000 0,19572156 0,20779999 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,19572156 0,20770972 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,19572156 0,20761953 ! gonad development GO:0008406 115 66 0,000 0,19572156 0,20752942 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,19837393 0,21025054 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,19837393 0,21015937 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,19837393 0,21006827 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,19837393 0,20997725 ! secondary metabolic process GO:0019748 125 67 0,000 0,19837393 0,20988632 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,19837393 0,20979546 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,20101762 0,21249937 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,20101762 0,21240746 ! hexose catabolic process GO:0019320 113 68 0,000 0,20101762 0,21231563 ! extracellular matrix organization GO:0030198 146 68 0,000 0,20101762 0,21222387 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,20101762 0,2121322 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,20101762 0,21204061 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,20101762 0,21194909 ! adaptive immune response GO:0002250 126 68 0,000 0,20101762 0,21185765 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,20101762 0,2117663 ! cell projection assembly GO:0030031 138 68 0,000 0,20101762 0,21167502 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,20365267 0,21435737 ! lung development GO:0030324 165 69 0,000 0,20365267 0,21426506 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,20365267 0,21417282 ! urogenital system development GO:0001655 149 69 0,000 0,20365267 0,21408066 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,20365267 0,21398859 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,20365267 0,21389659 ! developmental maturation GO:0021700 128 69 0,000 0,20365267 0,21380467 ! single fertilization GO:0007338 83 69 0,000 0,20365267 0,21371283 ! cell redox homeostasis GO:0045454 114 70 0,000 0,2062791 0,21637606 ! germ cell development GO:0007281 133 70 0,000 0,2062791 0,21628319 ! activation of immune response GO:0002253 120 70 0,000 0,2062791 0,2161904 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,2062791 0,2160977 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,20889694 0,21874635 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,20889694 0,21865262 ! appendage morphogenesis GO:0035107 150 72 0,000 0,21150622 0,22128895 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,21150622 0,22119422 ! respiratory tube development GO:0030323 171 72 0,000 0,21150622 0,22109957 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,21150622 0,221005 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,21150622 0,22091052 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,21150622 0,22081611 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,21150622 0,22072179 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,21150622 0,22062754 ! appendage development GO:0048736 151 73 0,000 0,21410697 0,22324513 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,21410697 0,22314988 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,21410697 0,22305472 ! regulation of immune effector process GO:0002697 156 73 0,000 0,21410697 0,22295965 ! acute inflammatory response GO:0002526 118 74 0,000 0,21669921 0,22556292 ! amino acid transport GO:0006865 148 74 0,000 0,21669921 0,22546686 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,21669921 0,22537087 ! respiratory system development GO:0060541 175 74 0,000 0,21669921 0,22527497 ! transition metal ion transport GO:0000041 143 75 0,000 0,21928298 0,22786402 ! reproductive structure development GO:0048608 131 75 0,000 0,21928298 0,22776714 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,21928298 0,22767035 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,21928298 0,22757363 ! eye development GO:0001654 155 75 0,000 0,21928298 0,22747699 ! axon guidance GO:0007411 162 75 0,000 0,21928298 0,22738044 ! rhythmic process GO:0048511 142 75 0,000 0,21928298 0,22728397 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,2218583 0,22985573 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,2218583 0,2297583 ! learning or memory GO:0007611 161 76 0,000 0,2218583 0,22966094 ! regulation of blood pressure GO:0008217 134 76 0,000 0,2218583 0,22956367 ! amine catabolic process GO:0009310 136 77 0,000 0,22442519 0,2321214 ! neurotransmitter transport GO:0006836 142 77 0,000 0,22442519 0,23202317 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,22442519 0,23192502 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,22442519 0,23182695 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,22442519 0,23172897 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,22698369 0,23427172 ! antigen processing and presentation GO:0019882 117 78 0,000 0,22698369 0,23417278 ! fertilization GO:0009566 99 78 0,000 0,22698369 0,23407393 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,22698369 0,23397517 ! blood coagulation GO:0007596 151 79 0,000 0,22953382 0,23650406 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,22953382 0,23640435 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,22953382 0,23630473 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,22953382 0,23620519 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,22953382 0,23610573 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,22953382 0,23600636 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,23207561 0,23851944 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,23207561 0,23841914 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,23207561 0,23831892 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,23207561 0,23821879 ! meiosis GO:0007126 143 81 0,000 0,23460908 0,24071818 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 0,000 0,23460908 0,24061712 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,23713427 0,24310492 ! meiotic cell cycle GO:0051321 144 82 0,000 0,23713427 0,24300295 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,2396512 0,24547919 ! exocytosis GO:0006887 153 83 0,000 0,2396512 0,24537631 ! response to oxygen levels GO:0070482 183 83 0,000 0,2396512 0,24527351 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,2396512 0,2451708 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,2396512 0,24506818 ! inorganic anion transport GO:0015698 156 83 0,000 0,2396512 0,24496564 ! response to metal ion GO:0010038 158 84 0,000 0,24215989 0,24742644 ! digestion GO:0007586 130 84 0,000 0,24215989 0,247323 ! regulation of ligase activity GO:0051340 147 84 0,000 0,24215989 0,24721965 ! hemostasis GO:0007599 165 85 0,000 0,24466038 0,24966805 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,24466038 0,2495638 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,24466038 0,24945964 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,24466038 0,24935557 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,24715269 0,25179067 ! regulation of lyase activity GO:0051339 169 86 0,000 0,24715269 0,25168571 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,24715269 0,25158084 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,24963684 0,25400367 ! alcohol catabolic process GO:0046164 142 87 0,000 0,24963684 0,25389792 ! nucleosome assembly GO:0006334 126 87 0,000 0,24963684 0,25379226 ! cellular respiration GO:0045333 143 88 0,000 0,25211287 0,25620289 ! amine biosynthetic process GO:0009309 146 88 0,000 0,25211287 0,25609636 ! sensory perception of smell GO:0007608 117 88 0,000 0,25211287 0,25598992 ! chromatin assembly GO:0031497 128 88 0,000 0,25211287 0,25588356 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,25211287 0,2557773 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,25458079 0,25817388 ! tube morphogenesis GO:0035239 194 89 0,000 0,25458079 0,25806676 ! cellular defense response GO:0006968 123 89 0,000 0,25458079 0,25795972 ! regulation of neurological system process GO:0031644 175 89 0,000 0,25458079 0,25785277 ! response to inorganic substance GO:0010035 173 90 0,000 0,25704065 0,26023634 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,25704065 0,26012854 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,25704065 0,26002083 ! response to unfolded protein GO:0006986 139 90 0,000 0,25704065 0,2599132 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,25704065 0,25980567 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,25949245 0,26217537 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 0,000 0,25949245 0,26206699 ! defense response to bacterium GO:0042742 112 91 0,000 0,25949245 0,2619587 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,26193623 0,26431649 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,26437202 0,26666426 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,26437202 0,2665542 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,26437202 0,26644424 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,26679983 0,2687802 ! female pregnancy GO:0007565 166 94 0,000 0,26679983 0,26866941 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,26679983 0,26855871 ! regulation of membrane potential GO:0042391 179 94 0,000 0,26679983 0,2684481 ! regulation of defense response GO:0031347 171 95 0,000 0,2692197 0,2707714 ! nucleosome organization GO:0034728 143 95 0,000 0,2692197 0,27065997 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,2692197 0,27054864 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,2692197 0,27043739 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,2692197 0,27032624 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,2692197 0,27021517 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,2692197 0,2701042 ! sex differentiation GO:0007548 171 96 0,000 0,27163166 0,27241221 ! response to protein stimulus GO:0051789 158 96 0,000 0,27163166 0,27230042 ! regulation of T cell activation GO:0050863 175 96 0,000 0,27163166 0,27218873 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,27403571 0,27448514 ! forebrain development GO:0030900 210 98 0,000 0,27643191 0,27677178 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,27643191 0,2766584 ! mRNA transport GO:0051028 185 100 0,000 0,28120079 0,28131594 ! positive regulation of immune response GO:0050778 175 100 0,000 0,28120079 0,28120079