pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6586-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! histone modification GO:0016570 91 50 5,000 4,39E-07 1,056E-03 ! covalent chromatin modification GO:0016569 101 52 5,000 5,571E-07 6,702E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 6,000 1,372E-06 1,1E-03 ! interphase GO:0051325 213 98 6,000 1,692E-06 1,018E-03 ! activation of MAPKKK activity GO:0000185 12 6 2,000 3,743E-06 1,801E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 6,522E-06 2,615E-03 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 8,509E-06 2,925E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,039E-05 3,125E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,039E-05 2,778E-03 ! chromatin remodeling GO:0006338 109 51 4,000 1,151E-05 2,77E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 1,151E-05 2,518E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,552E-05 3,112E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,995E-05 3,693E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,208E-05 3,794E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 3,023E-05 4,848E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 4,013E-05 6,035E-03 ! histone acetylation GO:0016573 26 12 2,000 4,013E-05 5,68E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 4,013E-05 5,364E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 4,013E-05 5,082E-03 GO:0042130|negative regulation of T cell proliferation, ! actin filament organization GO:0007015 148 66 4,000 4,084E-05 4,913E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 4,393E-05 5,033E-03 ! negative regulation of kinase activity GO:0033673 131 68 4,000 4,719E-05 5,161E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 6,217E-05 6,504E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 6,584E-05 6,6E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 6,584E-05 6,336E-03 ! histone deacetylation GO:0016575 20 15 2,000 8,195E-05 7,583E-03 ! regulation of T cell proliferation GO:0042129 71 41 3,000 9,224E-05 8,22E-03 ! G1 phase of mitotic cell cycle GO:0000080 35 16 2,000 1,004E-04 8,63E-03 ! activation of MAPKK activity GO:0000186 35 16 2,000 1,004E-04 8,332E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,004E-04 8,054E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! response to hypoxia GO:0001666 171 81 4,000 1,092E-04 8,474E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,114E-04 8,376E-03 ! signal complex assembly GO:0007172 41 17 2,000 1,214E-04 8,854E-03 ! response to oxygen levels GO:0070482 176 83 4,000 1,226E-04 8,675E-03 ! nucleosome assembly GO:0006334 122 85 4,000 1,372E-04 9,432E-03 ! chromatin assembly GO:0031497 124 86 4,000 1,45E-04 9,691E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 1,453E-04 9,45E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 1,716E-04 0,01086349 ! G1 phase GO:0051318 40 19 2,000 1,716E-04 0,01058494 ! protein-DNA complex assembly GO:0065004 130 90 4,000 1,796E-04 0,01080404 ! nucleosome organization GO:0034728 138 92 4,000 1,991E-04 0,01168534 ! protein amino acid deacetylation GO:0006476 29 20 2,000 2,01E-04 0,01151433 ! protein amino acid acetylation GO:0006473 39 20 2,000 2,01E-04 0,01124656 ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,01E-04 0,01099096 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,692E-04 0,01439466 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 3,083E-04 0,01612537 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 3,083E-04 0,01578227 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,281E-04 0,01644647 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 3,281E-04 0,01611083 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 3,281E-04 0,01578861 ! valine metabolic process GO:0006573 10 5 1,000 3,281E-04 0,01547903 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 3,281E-04 0,01518135 GO:0051489|regulation of filopodium assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,281E-04 0,01489491 ! positive regulation of transporter activity GO:0032411 8 5 1,000 3,281E-04 0,01461908 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,281E-04 0,01435328 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 1,000 3,281E-04 0,01409697 ! cellular glucose homeostasis GO:0001678 5 5 1,000 3,281E-04 0,01384966 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,281E-04 0,01361087 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,281E-04 0,01338018 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,281E-04 0,01315717 ! stem cell division GO:0017145 11 5 1,000 3,281E-04 0,01294148 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 1,000 3,281E-04 0,01273275 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 3,508E-04 0,01339908 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 3,508E-04 0,01318972 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 3,97E-04 0,01469522 ! protein amino acid alkylation GO:0008213 53 25 2,000 3,97E-04 0,01447257 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 2,000 3,97E-04 0,01425656 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 4,469E-04 0,01581187 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 4,469E-04 0,01558272 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 4,903E-04 0,01685204 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 4,903E-04 0,01661469 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 4,903E-04 0,01638393 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! establishment of spindle localization GO:0051293 12 6 1,000 4,903E-04 0,01615949 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 14 6 1,000 4,903E-04 0,01594112 ! purine base biosynthetic process GO:0009113 17 6 1,000 4,903E-04 0,01572857 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,903E-04 0,01552162 ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,903E-04 0,01532004 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 5,006E-04 0,01544215 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 5,006E-04 0,01524668 ! protein amino acid acylation GO:0043543 55 27 2,000 5,006E-04 0,0150561 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 5,006E-04 0,01487022 ! positive regulation of cell motion GO:0051272 146 64 3,000 5,219E-04 0,01531433 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 6,201E-04 0,01797562 ! lung development GO:0030324 144 67 3,000 6,212E-04 0,01779366 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 6,838E-04 0,01935557 ! mRNA stabilization GO:0048255 18 7 1,000 6,838E-04 0,0191305 GO:0043489|RNA stabilization, ! cranial nerve morphogenesis GO:0021602 11 7 1,000 6,838E-04 0,01891061 ! prostate gland development GO:0030850 13 7 1,000 6,838E-04 0,01869572 ! regulation of lipid catabolic process GO:0050994 15 7 1,000 6,838E-04 0,01848566 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 6,838E-04 0,01828026 ! transcription termination GO:0006353 13 7 1,000 6,838E-04 0,01807938 ! cell junction assembly GO:0034329 78 30 2,000 6,861E-04 0,01794282 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 6,861E-04 0,01774989 ! regulation of B cell activation GO:0050864 50 30 2,000 6,861E-04 0,01756106 ! respiratory tube development GO:0030323 150 70 3,000 7,332E-04 0,01856974 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 7,564E-04 0,01895704 GO:0043433|negative regulation of transcription factor activity, ! respiratory system development GO:0060541 153 72 3,000 8,154E-04 0,02022447 ! regulation of transcription factor activity GO:0051090 126 74 3,000 9,038E-04 0,02218933 GO:0090046|regulation of transcription regulator activity, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 9,083E-04 0,02207371 ! succinate metabolic process GO:0006105 14 8 1,000 9,083E-04 0,02185298 ! T-helper 1 type immune response GO:0042088 12 8 1,000 9,083E-04 0,02163661 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 9,083E-04 0,02142449 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 9,083E-04 0,02121648 ! regulation of vascular permeability GO:0043114 12 8 1,000 9,083E-04 0,02101248 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 9,083E-04 0,02081236 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 9,083E-04 0,02061601 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 9,104E-04 0,02047027 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 3,000 1,101E-03 0,02451845 ! activation of protein kinase activity GO:0032147 147 79 3,000 1,154E-03 0,02547504 ! Golgi to endosome transport GO:0006895 23 9 1,000 1,163E-03 0,02544545 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,163E-03 0,02521621 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,163E-03 0,02499106 GO:0006600|creatine metabolic process, ! receptor clustering GO:0043113 18 9 1,000 1,163E-03 0,0247699 ! motor axon guidance GO:0008045 16 9 1,000 1,163E-03 0,02455262 ! S phase GO:0051320 9 9 1,000 1,163E-03 0,02433912 GO:0000084|S phase of mitotic cell cycle, ! musculoskeletal movement GO:0050881 14 9 1,000 1,163E-03 0,0241293 GO:0050879|multicellular organismal movement, ! purine base metabolic process GO:0006144 21 9 1,000 1,163E-03 0,02392307 ! cell junction organization GO:0034330 86 36 2,000 1,176E-03 0,02398468 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,176E-03 0,02378313 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,275E-03 0,02555761 ! regulation of protein stability GO:0031647 73 37 2,000 1,275E-03 0,02534639 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,275E-03 0,02513863 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,326E-03 0,02593013 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,378E-03 0,02673982 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 1,378E-03 0,0265259 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,449E-03 0,02766246 ! lung alveolus development GO:0048286 26 10 1,000 1,449E-03 0,02744464 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,449E-03 0,02723023 ! nucleobase biosynthetic process GO:0046112 24 10 1,000 1,449E-03 0,02701914 ! epithelial cell development GO:0002064 20 10 1,000 1,449E-03 0,0268113 ! regulation of bone resorption GO:0045124 25 10 1,000 1,449E-03 0,02660664 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 1,449E-03 0,02640507 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,449E-03 0,02620654 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,449E-03 0,02601097 ! localization within membrane GO:0051668 20 10 1,000 1,449E-03 0,02581829 ! negative regulation of binding GO:0051100 72 40 2,000 1,6E-03 0,02831322 ! cytokinesis GO:0000910 72 40 2,000 1,6E-03 0,02810656 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,719E-03 0,02997879 ! regulation of DNA binding GO:0051101 155 88 3,000 1,721E-03 0,02978275 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,764E-03 0,03031326 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 1,764E-03 0,03009827 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,764E-03 0,02988631 ! blood vessel remodeling GO:0001974 29 11 1,000 1,764E-03 0,02967732 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,764E-03 0,02947123 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,764E-03 0,02926798 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,764E-03 0,02906751 ! lamellipodium assembly GO:0030032 20 11 1,000 1,764E-03 0,02886977 ! regulation of cell adhesion GO:0030155 212 89 3,000 1,794E-03 0,02915757 ! neuron migration GO:0001764 79 42 2,000 1,844E-03 0,02977534 ! epithelial cell differentiation GO:0030855 79 43 2,000 1,974E-03 0,03166108 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,107E-03 0,03357014 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,109E-03 0,03337708 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 2,109E-03 0,03315893 ! cartilage condensation GO:0001502 20 12 1,000 2,109E-03 0,03294361 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,109E-03 0,03273107 GO:0050927|positive regulation of positive chemotaxis, ! protein complex disassembly GO:0043241 27 12 1,000 2,109E-03 0,03252126 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,109E-03 0,03231412 ! regulation of cell projection assembly GO:0060491 30 12 1,000 2,109E-03 0,0321096 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,109E-03 0,03190765 ! focal adhesion formation GO:0048041 35 12 1,000 2,109E-03 0,03170823 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 2,109E-03 0,03151128 ! cranial nerve development GO:0021545 20 12 1,000 2,109E-03 0,03131677 ! histone methylation GO:0016571 26 12 1,000 2,109E-03 0,03112464 ! autonomic nervous system development GO:0048483 24 12 1,000 2,109E-03 0,03093486 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,109E-03 0,03074737 ! biopolymer methylation GO:0043414 84 44 2,000 2,109E-03 0,03057341 ! transcription initiation GO:0006352 153 94 3,000 2,191E-03 0,0315619 ! regulation of T cell activation GO:0050863 158 94 3,000 2,191E-03 0,03137403 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,397E-03 0,03413121 ! response to insulin stimulus GO:0032868 95 46 2,000 2,397E-03 0,03393043 ! positive regulation of lipid metabolic process GO:0045834 25 13 1,000 2,483E-03 0,03492989 ! plasma membrane organization GO:0007009 24 13 1,000 2,483E-03 0,03472681 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 2,483E-03 0,03452608 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 1,000 2,483E-03 0,03432765 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,483E-03 0,0341315 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,483E-03 0,03393757 ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 2,483E-03 0,03374583 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 2,483E-03 0,03355625 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,483E-03 0,03336878 ! endosome transport GO:0016197 108 47 2,000 2,55E-03 0,03408621 ! methylation GO:0032259 90 47 2,000 2,55E-03 0,03389788 ! skeletal muscle tissue development GO:0007519 186 99 3,000 2,645E-03 0,03496216 GO:0060538|skeletal muscle organ development, ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,709E-03 0,03561205 ! cellular component disassembly GO:0022411 86 48 2,000 2,709E-03 0,0354185 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,709E-03 0,03522705 ! cell cycle arrest GO:0007050 213 100 3,000 2,743E-03 0,03547739 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 2,873E-03 0,03696692 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 2,885E-03 0,03692613 ! regulation of RNA stability GO:0043487 32 14 1,000 2,885E-03 0,03673076 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,044E-03 0,03854274 ! regulation of cell shape GO:0008360 125 51 2,000 3,22E-03 0,04056593 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,317E-03 0,04156145 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 3,317E-03 0,0413461 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! response to UV GO:0009411 104 53 2,000 3,592E-03 0,04454994 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 3,776E-03 0,04659102 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 3,776E-03 0,04635331 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,776E-03 0,04611802 ! DNA replication initiation GO:0006270 27 16 1,000 3,776E-03 0,0458851 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,776E-03 0,04565452 ! negative regulation of cell motion GO:0051271 134 55 2,000 3,989E-03 0,04798932 ! regulation of DNA replication GO:0006275 101 56 2,000 4,197E-03 0,05024154 ! positive regulation of organelle organization GO:0010638 100 56 2,000 4,197E-03 0,04999282 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 4,263E-03 0,05053035 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,263E-03 0,05028265 ! inositol metabolic process GO:0006020 28 17 1,000 4,263E-03 0,05003737 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,263E-03 0,04979447 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,263E-03 0,04955392 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,263E-03 0,04931568 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,263E-03 0,04907972 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 4,263E-03 0,048846 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,263E-03 0,04861451 ! nucleobase metabolic process GO:0009112 37 17 1,000 4,263E-03 0,04838519 ! regulation of bone remodeling GO:0046850 137 57 2,000 4,412E-03 0,04983486 ! positive regulation of cell migration GO:0030335 126 57 2,000 4,412E-03 0,04960198 ! regulation of tissue remodeling GO:0034103 140 58 2,000 4,633E-03 0,05184572 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,778E-03 0,05322328 ! glutamine metabolic process GO:0006541 29 18 1,000 4,778E-03 0,05297802 ! cell-substrate junction assembly GO:0007044 54 18 1,000 4,778E-03 0,052735 ! nerve development GO:0021675 28 18 1,000 4,778E-03 0,0524942 ! skeletal system morphogenesis GO:0048705 105 59 2,000 4,861E-03 0,05315772 ! DNA catabolic process GO:0006308 86 59 2,000 4,861E-03 0,05291719 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 5,095E-03 0,05521877 ! lipid phosphorylation GO:0046834 35 19 1,000 5,32E-03 0,05739982 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,32E-03 0,05714357 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,32E-03 0,0568896 ! neuromuscular junction development GO:0007528 34 19 1,000 5,32E-03 0,05663788 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,32E-03 0,05638837 ! cell-cell junction organization GO:0045216 35 19 1,000 5,32E-03 0,05614106 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,336E-03 0,05606358 ! regulation of homeostatic process GO:0032844 134 62 2,000 5,584E-03 0,05841218 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 5,889E-03 0,06133622 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,889E-03 0,06107184 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 5,889E-03 0,06080973 ! cellular response to starvation GO:0009267 33 20 1,000 5,889E-03 0,06054986 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 5,889E-03 0,0602922 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 5,889E-03 0,06003673 ! leukotriene biosynthetic process GO:0019370 37 20 1,000 5,889E-03 0,05978341 GO:0043450|alkene biosynthetic process, ! actin filament-based movement GO:0030048 43 20 1,000 5,889E-03 0,05953221 ! hindlimb morphogenesis GO:0035137 43 21 1,000 6,484E-03 0,06527602 ! cellular macromolecular complex disassembly GO:0034623 43 21 1,000 6,484E-03 0,06500403 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 6,484E-03 0,06473431 ! positive regulation of locomotion GO:0040017 39 21 1,000 6,484E-03 0,06446681 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of cell growth GO:0030308 132 67 2,000 6,926E-03 0,06857541 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 6,926E-03 0,06829436 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 7,106E-03 0,06978077 ! regulation of chemotaxis GO:0050920 40 22 1,000 7,106E-03 0,06949711 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 7,106E-03 0,06921574 ! vesicle docking during exocytosis GO:0006904 41 22 1,000 7,106E-03 0,06893665 ! apoptotic nuclear changes GO:0030262 32 22 1,000 7,106E-03 0,06865979 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,106E-03 0,06838515 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,106E-03 0,0681127 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 7,106E-03 0,06784242 ! protein stabilization GO:0050821 39 22 1,000 7,106E-03 0,06757426 ! negative regulation of ligase activity GO:0051352 112 68 2,000 7,215E-03 0,06834628 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cell cycle checkpoint GO:0000075 137 69 2,000 7,512E-03 0,0708749 ! negative regulation of cell size GO:0045792 134 69 2,000 7,512E-03 0,07059805 ! urogenital system development GO:0001655 137 69 2,000 7,512E-03 0,07032335 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 7,753E-03 0,07230179 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 7,753E-03 0,07202263 ! sex determination GO:0007530 47 23 1,000 7,753E-03 0,07174562 ! leukotriene metabolic process GO:0006691 42 23 1,000 7,753E-03 0,07147074 ! fatty acid transport GO:0015908 44 23 1,000 7,753E-03 0,07119795 ! negative regulation of catabolic process GO:0009895 50 23 1,000 7,753E-03 0,07092723 ! reproductive structure development GO:0048608 113 71 2,000 8,126E-03 0,07405608 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,426E-03 0,07650161 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 8,426E-03 0,07621401 ! regulation of transmembrane transport GO:0034762 38 24 1,000 8,426E-03 0,07592857 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 8,426E-03 0,07564525 ! vesicle docking GO:0048278 47 24 1,000 8,426E-03 0,07536404 ! regulation of behavior GO:0050795 43 24 1,000 8,426E-03 0,07508492 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 8,426E-03 0,07480785 ! cellular alkene metabolic process GO:0043449 43 24 1,000 8,426E-03 0,07453282 ! learning or memory GO:0007611 147 73 2,000 8,769E-03 0,0772808 ! eye development GO:0001654 143 74 2,000 9,101E-03 0,07991688 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 9,124E-03 0,07982811 ! myelination GO:0042552 45 25 1,000 9,124E-03 0,07953888 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 9,124E-03 0,07925174 ! negative regulation of DNA replication GO:0008156 42 25 1,000 9,124E-03 0,07896666 ! receptor metabolic process GO:0043112 46 25 1,000 9,124E-03 0,07868362 ! response to starvation GO:0042594 42 25 1,000 9,124E-03 0,07840261 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 9,124E-03 0,0781236 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 9,124E-03 0,07784656 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 9,124E-03 0,07757149 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,124E-03 0,07729835 ! neural tube closure GO:0001843 49 25 1,000 9,124E-03 0,07702713 GO:0060606|tube closure, ! cell-matrix adhesion GO:0007160 163 75 2,000 9,441E-03 0,07942072 ! regulation of catabolic process GO:0009894 161 76 2,000 9,788E-03 0,08205239 ! tube lumen formation GO:0035148 50 26 1,000 9,847E-03 0,08226571 ! macromolecular complex disassembly GO:0032984 53 26 1,000 9,847E-03 0,08198105 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 9,847E-03 0,08169836 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 9,847E-03 0,08141761 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 9,847E-03 0,08113878 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 9,847E-03 0,08086186 ! positive regulation of nuclear division GO:0051785 40 26 1,000 9,847E-03 0,08058682 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 9,847E-03 0,08031364 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 0,01014191 0,08243724 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,010595 0,08583019 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 0,010595 0,08554217 ! male gonad development GO:0008584 44 27 1,000 0,010595 0,08525608 ! primary neural tube formation GO:0014020 51 27 1,000 0,010595 0,08497189 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,010595 0,08468959 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 0,01087262 0,0866209 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 0,01087262 0,08633503 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01136705 0,08996423 ! T cell activation GO:0042110 168 81 2,000 0,01163305 0,09176757 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 0,01163305 0,09146768 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01163305 0,09116974 ! icosanoid biosynthetic process GO:0046456 54 29 1,000 0,01216312 0,09501451 ! negative regulation of growth GO:0045926 155 84 2,000 0,01282984 0,09989834 ! regulation of ligase activity GO:0051340 142 84 2,000 0,01282984 0,09957609 ! membrane docking GO:0022406 61 30 1,000 0,01298291 0,10044013 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01298291 0,1001182 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01298291 0,09979834 GO:0008366|axon ensheathment, ! one-carbon metabolic process GO:0006730 154 85 2,000 0,01324383 0,10147976 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01324383 0,1011576 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 2,000 0,01366538 0,10404713 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01382612 0,10493892 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01382612 0,10460892 ! mesoderm formation GO:0001707 69 31 1,000 0,01382612 0,104281 ! gland development GO:0048732 206 88 2,000 0,01453123 0,10925669 ! spindle organization GO:0007051 46 32 1,000 0,01469245 0,11012473 ! pigment biosynthetic process GO:0046148 66 32 1,000 0,01469245 0,10978272 ! metanephros development GO:0001656 74 32 1,000 0,01469245 0,10944284 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 1,000 0,01469245 0,10910505 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01469245 0,10876934 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01469245 0,1084357 ! hindbrain development GO:0030902 61 32 1,000 0,01469245 0,10810409 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01469245 0,1077745 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,01497557 0,10951737 ! ossification GO:0001503 188 90 2,000 0,01542753 0,11248072 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01542753 0,1121409 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01558162 0,1129198 ! cell fate specification GO:0001708 52 33 1,000 0,01558162 0,1125807 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01558162 0,11224363 ! bone development GO:0060348 189 91 2,000 0,01588713 0,11410281 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01649333 0,11810402 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01649333 0,11775356 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01649333 0,11740518 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01649333 0,11705885 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01682931 0,11909209 ! regulation of muscle development GO:0048634 70 35 1,000 0,0174273 0,12296211 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,0174273 0,12260257 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,0174273 0,12224513 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,0174273 0,12188976 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,0174273 0,12153646 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,0174273 0,1211852 ! cytokine production GO:0001816 59 35 1,000 0,0174273 0,12083596 ! neural tube formation GO:0001841 67 35 1,000 0,0174273 0,12048873 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01838324 0,12673373 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01838324 0,12637163 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01838324 0,1260116 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01838324 0,12565361 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01838324 0,12529765 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01838324 0,12494371 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,0188058 0,12745564 ! meiosis I GO:0007127 65 37 1,000 0,01936087 0,13084902 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01936087 0,1304825 ! tissue remodeling GO:0048771 76 37 1,000 0,01936087 0,13011802 ! pigment metabolic process GO:0042440 80 37 1,000 0,01936087 0,12975558 ! nucleus organization GO:0006997 67 38 1,000 0,02035991 0,13607208 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02035991 0,13569515 ! mammary gland development GO:0030879 86 39 1,000 0,02138009 0,1421008 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02138009 0,14170934 ! segmentation GO:0035282 67 39 1,000 0,02138009 0,14132003 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02138009 0,14093285 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,02242112 0,14739132 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02242112 0,14698971 ! maintenance of protein location GO:0045185 91 40 1,000 0,02242112 0,14659028 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02348275 0,15311514 ! gliogenesis GO:0042063 88 41 1,000 0,02348275 0,15270132 ! T cell differentiation GO:0030217 81 41 1,000 0,02348275 0,15228972 ! polyol metabolic process GO:0019751 66 41 1,000 0,02348275 0,15188034 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02348275 0,15147315 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02456469 0,15802844 GO:0090047|positive regulation of transcription regulator activity, ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,02456469 0,15760703 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,02456469 0,15718786 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02456469 0,15677091 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02456469 0,15635618 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02566668 0,16293938 ! neural tube development GO:0021915 77 43 1,000 0,02566668 0,16251059 ! male sex differentiation GO:0046661 76 44 1,000 0,02678845 0,16916802 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02678845 0,16872517 ! developmental growth GO:0048589 82 44 1,000 0,02678845 0,16828464 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02678845 0,1678464 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,02792975 0,1745428 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02792975 0,17409062 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02792975 0,17364077 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,02792975 0,17319325 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,02792975 0,17274802 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,02792975 0,17230508 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02855735 0,17572627 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02855735 0,17527799 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02855735 0,17483199 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02855735 0,17438826 ! neuron fate determination GO:0048664 7 5 0,000 0,02855735 0,17394677 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02855735 0,17350751 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02855735 0,17307046 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02855735 0,17263561 ! polyol transport GO:0015791 12 5 0,000 0,02855735 0,17220294 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02855735 0,17177243 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02855735 0,17134407 ! response to superoxide GO:0000303 10 5 0,000 0,02855735 0,17091784 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02855735 0,17049373 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02855735 0,17007172 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02855735 0,16965179 ! female meiosis GO:0007143 7 5 0,000 0,02855735 0,16923392 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02855735 0,16881812 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02855735 0,16840435 ! cobalt ion transport GO:0006824 11 5 0,000 0,02855735 0,1679926 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02855735 0,16758286 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02855735 0,16717512 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02855735 0,16676935 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02855735 0,16636555 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02855735 0,1659637 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02855735 0,16556379 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02855735 0,1651658 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02855735 0,16476972 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02855735 0,16437553 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02855735 0,16398323 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02855735 0,16359279 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02855735 0,16320421 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02855735 0,16281747 ! negative chemotaxis GO:0050919 14 5 0,000 0,02855735 0,16243256 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02855735 0,16204947 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02855735 0,16166817 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02855735 0,16128867 ! behavioral response to pain GO:0048266 9 5 0,000 0,02855735 0,16091094 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02855735 0,16053498 ! Notch receptor processing GO:0007220 8 5 0,000 0,02855735 0,16016078 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02855735 0,15978831 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02855735 0,15941757 ! micturition GO:0060073 9 5 0,000 0,02855735 0,15904855 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02855735 0,15868123 ! copulation GO:0007620 9 5 0,000 0,02855735 0,15831561 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02855735 0,15795166 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02855735 0,15758939 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02855735 0,15722877 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02855735 0,1568698 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02855735 0,15651247 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02855735 0,15615676 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02855735 0,15580266 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02855735 0,15545017 ! grooming behavior GO:0007625 6 5 0,000 0,02855735 0,15509926 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02855735 0,15474994 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02855735 0,15440219 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02855735 0,15405599 ! response to protozoan GO:0001562 10 5 0,000 0,02855735 0,15371135 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02855735 0,15336824 ! lymph vessel development GO:0001945 10 5 0,000 0,02855735 0,15302667 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02855735 0,15268661 ! endochondral ossification GO:0001958 16 5 0,000 0,02855735 0,15234806 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02855735 0,152011 ! parathyroid gland development GO:0060017 13 5 0,000 0,02855735 0,15167544 ! anagen GO:0042640 6 5 0,000 0,02855735 0,15134135 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02855735 0,15100873 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02855735 0,15067757 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02855735 0,15034786 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02855735 0,15001959 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02855735 0,14969275 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02855735 0,14936733 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02855735 0,14904333 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02855735 0,14872072 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02855735 0,14839951 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02855735 0,14807968 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02855735 0,14776123 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02855735 0,14744415 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02855735 0,14712842 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02855735 0,14681405 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02855735 0,14650101 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02855735 0,1461893 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02855735 0,14587892 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02855735 0,14556986 ! histidine catabolic process GO:0006548 6 5 0,000 0,02855735 0,1452621 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02855735 0,14495564 ! microvillus organization GO:0032528 7 5 0,000 0,02855735 0,14465047 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02855735 0,14434658 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02855735 0,14404397 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02855735 0,14374262 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02855735 0,14344253 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02855735 0,14314369 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02855735 0,1428461 ! polyol catabolic process GO:0046174 7 5 0,000 0,02855735 0,14254974 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02855735 0,1422546 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02855735 0,14196069 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02855735 0,14166799 ! muscle cell migration GO:0014812 8 5 0,000 0,02855735 0,14137649 ! mitochondrial fission GO:0000266 8 5 0,000 0,02855735 0,14108619 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02855735 0,14079708 ! mRNA transcription GO:0009299 9 5 0,000 0,02855735 0,14050915 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02855735 0,14022239 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02855735 0,13993681 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02855735 0,13965238 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02855735 0,13936911 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02855735 0,13908699 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02855735 0,13880601 ! response to food GO:0032094 6 5 0,000 0,02855735 0,13852616 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02855735 0,13824743 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02855735 0,13796983 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02855735 0,13769333 ! forebrain neuron development GO:0021884 13 5 0,000 0,02855735 0,13741795 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02855735 0,13714366 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02855735 0,13687046 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02855735 0,13659836 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02855735 0,13632733 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02855735 0,13605737 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02855735 0,13578848 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02855735 0,13552066 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02855735 0,13525388 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02855735 0,13498816 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02855735 0,13472348 ! basic amino acid transport GO:0015802 11 5 0,000 0,02855735 0,13445983 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02855735 0,13419721 ! depyrimidination GO:0045008 10 5 0,000 0,02855735 0,13393562 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02855735 0,13367505 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02855735 0,13341548 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02855735 0,13315692 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02855735 0,13289937 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02855735 0,13264281 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02855735 0,13238723 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02855735 0,13213264 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02855735 0,13187903 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02855735 0,13162639 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02855735 0,13137471 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02855735 0,13112399 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02855735 0,13087423 ! response to arsenic GO:0046685 10 5 0,000 0,02855735 0,13062542 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02855735 0,13037756 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02855735 0,13013063 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02855735 0,12988464 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02855735 0,12963957 ! response to cadmium ion GO:0046686 7 5 0,000 0,02855735 0,12939543 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02855735 0,12915221 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02855735 0,12890989 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02855735 0,12866849 ! decidualization GO:0046697 11 5 0,000 0,02855735 0,12842799 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02855735 0,12818838 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02855735 0,12794967 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02855735 0,12771185 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02855735 0,1274749 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02855735 0,12723884 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02855735 0,12700365 ! neural tube patterning GO:0021532 7 5 0,000 0,02855735 0,12676932 ! embryonic cleavage GO:0040016 6 5 0,000 0,02855735 0,12653586 ! peroxisome fission GO:0016559 5 5 0,000 0,02855735 0,12630326 ! histone demethylation GO:0016577 10 5 0,000 0,02855735 0,12607151 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02855735 0,12584061 ! mitotic recombination GO:0006312 9 5 0,000 0,02855735 0,12561055 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02855735 0,12538134 ! metaphase plate congression GO:0051310 7 5 0,000 0,02855735 0,12515296 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02855735 0,12492541 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02855735 0,12469868 ! enteric nervous system development GO:0048484 8 5 0,000 0,02855735 0,12447278 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02855735 0,12424769 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02855735 0,12402342 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02855735 0,12379995 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02855735 0,12357729 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02855735 0,12335543 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02855735 0,12313436 ! plasminogen activation GO:0031639 5 5 0,000 0,02855735 0,12291408 ! B cell homeostasis GO:0001782 13 5 0,000 0,02855735 0,1226946 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02855735 0,12247589 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02855735 0,12225796 ! metaphase GO:0051323 8 5 0,000 0,02855735 0,12204081 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02855735 0,12182442 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02855735 0,1216088 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02855735 0,12139395 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02855735 0,12117985 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02855735 0,1209665 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02855735 0,12075391 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02855735 0,12054206 ! response to redox state GO:0051775 5 5 0,000 0,02855735 0,12033095 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02855735 0,12012058 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02855735 0,11991095 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02855735 0,11970204 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02855735 0,11949387 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02855735 0,11928641 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02855735 0,11907968 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02855735 0,11887366 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02855735 0,11866835 ! striatum development GO:0021756 9 5 0,000 0,02855735 0,11846375 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02855735 0,11825985 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02855735 0,11805666 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02855735 0,11785416 ! glial cell migration GO:0008347 11 5 0,000 0,02855735 0,11765235 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02855735 0,11745124 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02855735 0,11725081 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02855735 0,11705106 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02855735 0,116852 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02855735 0,1166536 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02855735 0,11645589 ! neuroprotection GO:0043526 6 5 0,000 0,02855735 0,11625884 ! neural plate development GO:0001840 8 5 0,000 0,02855735 0,11606245 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02855735 0,11586673 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02855735 0,11567167 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02855735 0,11547727 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02855735 0,11528351 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02855735 0,11509041 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02855735 0,11489795 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02855735 0,11470613 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02855735 0,11451496 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02855735 0,11432441 ! spindle assembly GO:0051225 6 5 0,000 0,02855735 0,11413451 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02855735 0,11394523 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02855735 0,11375658 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02855735 0,11356855 ! drug metabolic process GO:0017144 6 5 0,000 0,02855735 0,11338114 ! organ regeneration GO:0031100 7 5 0,000 0,02855735 0,11319435 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02855735 0,11300818 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02855735 0,11282262 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02855735 0,11263766 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,02909031 0,11455203 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02909031 0,11436485 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03026988 0,11880803 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03026988 0,11861453 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,03146819 0,1231097 ! activation of caspase activity GO:0006919 84 48 1,000 0,03146819 0,12290985 ! regulation of action potential GO:0001508 95 49 1,000 0,032685 0,12745561 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,032685 0,12724937 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,03392006 0,13184435 ! neuromuscular process GO:0050905 99 50 1,000 0,03392006 0,1316317 ! regulation of ossification GO:0030278 117 50 1,000 0,03392006 0,13141973 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03417076 0,1321782 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03417076 0,13196603 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03417076 0,13175455 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03417076 0,13154374 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03417076 0,13133361 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03417076 0,13112415 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03417076 0,13091535 ! sleep GO:0030431 13 6 0,000 0,03417076 0,13070722 ! response to oxygen radical GO:0000305 11 6 0,000 0,03417076 0,13049974 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03417076 0,13029293 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03417076 0,13008677 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03417076 0,12988126 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03417076 0,1296764 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03417076 0,12947219 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03417076 0,12926862 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03417076 0,12906568 ! forebrain regionalization GO:0021871 8 6 0,000 0,03417076 0,12886338 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03417076 0,12866172 ! male meiosis GO:0007140 7 6 0,000 0,03417076 0,12846069 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03417076 0,12826028 ! response to zinc ion GO:0010043 9 6 0,000 0,03417076 0,1280605 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03417076 0,12786134 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03417076 0,12766279 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03417076 0,12746487 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03417076 0,12726755 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03417076 0,12707085 ! malate metabolic process GO:0006108 11 6 0,000 0,03417076 0,12687475 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03417076 0,12667926 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03417076 0,12648437 ! protein refolding GO:0042026 15 6 0,000 0,03417076 0,12629008 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03417076 0,12609638 ! opsonization GO:0008228 8 6 0,000 0,03417076 0,12590328 ! mating behavior GO:0007617 7 6 0,000 0,03417076 0,12571076 ! neuron remodeling GO:0016322 15 6 0,000 0,03417076 0,12551884 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03417076 0,1253275 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03417076 0,12513674 ! equilibrioception GO:0050957 14 6 0,000 0,03417076 0,12494656 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03417076 0,12475696 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03417076 0,12456794 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03417076 0,12437948 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03417076 0,1241916 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03417076 0,12400428 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03417076 0,12381753 ! toxin metabolic process GO:0009404 11 6 0,000 0,03417076 0,12363134 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03417076 0,1234457 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03417076 0,12326063 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03417076 0,12307611 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03417076 0,12289214 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03417076 0,12270872 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03417076 0,12252584 ! thymic T cell selection GO:0045061 12 6 0,000 0,03417076 0,12234351 ! protein lipoylation GO:0009249 10 6 0,000 0,03417076 0,12216172 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03417076 0,12198047 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03417076 0,12179976 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03417076 0,12161958 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03417076 0,12143994 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03417076 0,12126082 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,03417076 0,12108224 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03417076 0,12090418 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03417076 0,12072664 ! hyperosmotic response GO:0006972 9 6 0,000 0,03417076 0,12054962 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03417076 0,12037312 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03417076 0,12019713 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03417076 0,12002166 ! urea metabolic process GO:0019627 7 6 0,000 0,03417076 0,1198467 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03417076 0,11967226 ! neutrophil activation GO:0042119 8 6 0,000 0,03417076 0,11949831 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03417076 0,11932488 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03417076 0,11915194 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03417076 0,11897951 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03417076 0,11880757 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03417076 0,11863613 ! neuron apoptosis GO:0051402 9 6 0,000 0,03417076 0,11846519 ! nucleoside salvage GO:0043174 9 6 0,000 0,03417076 0,11829473 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03417076 0,11812477 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03417076 0,11795529 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03417076 0,1177863 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03417076 0,1176178 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03417076 0,11744977 ! carnitine transport GO:0015879 10 6 0,000 0,03417076 0,11728222 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03417076 0,11711516 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03417076 0,11694856 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03417076 0,11678244 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03417076 0,11661679 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03417076 0,11645161 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03417076 0,1162869 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03417076 0,11612265 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03417076 0,11595887 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03417076 0,11579555 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03417076 0,11563269 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03417076 0,11547028 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03417076 0,11530833 ! response to UV-C GO:0010225 11 6 0,000 0,03417076 0,11514683 ! astrocyte development GO:0014002 15 6 0,000 0,03417076 0,11498579 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03417076 0,11482519 ! interaction with symbiont GO:0051702 13 6 0,000 0,03417076 0,11466505 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03417076 0,11450535 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03417076 0,11434609 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03417076 0,11418728 ! response to copper ion GO:0046688 10 6 0,000 0,03417076 0,1140289 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03417076 0,11387097 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03417076 0,11371347 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03417076 0,11355641 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03417076 0,11339978 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03417076 0,11324358 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03417076 0,11308781 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03417076 0,11293247 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03417076 0,11277756 ! hair follicle maturation GO:0048820 7 6 0,000 0,03417076 0,11262307 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03417076 0,112469 ! Schwann cell development GO:0014044 15 6 0,000 0,03417076 0,11231535 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03417076 0,11216213 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03417076 0,11200932 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03417076 0,11185692 ! subpallium development GO:0021544 10 6 0,000 0,03417076 0,11170494 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03417076 0,11155338 ! histone ubiquitination GO:0016574 8 6 0,000 0,03417076 0,11140222 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03417076 0,11125147 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03417076 0,11110113 ! G2 phase GO:0051319 16 6 0,000 0,03417076 0,1109512 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03417076 0,11080167 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03417076 0,11065254 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03417076 0,11050382 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03417076 0,11035549 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03417076 0,11020756 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03417076 0,11006003 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03417076 0,10991289 ! receptor internalization GO:0031623 10 6 0,000 0,03417076 0,10976614 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03417076 0,10961979 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03417076 0,10947382 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03417076 0,10932824 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03417076 0,10918305 ! protein deubiquitination GO:0016579 14 6 0,000 0,03417076 0,10903825 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03417076 0,10889383 ! protein destabilization GO:0031648 9 6 0,000 0,03417076 0,10874979 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03417076 0,10860613 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03417076 0,10846285 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03417076 0,10831995 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03417076 0,10817742 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03417076 0,10803527 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03417076 0,10789349 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03417076 0,10775208 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03417076 0,10761105 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03417076 0,10747038 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03417076 0,10733008 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03417076 0,10719014 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03417076 0,10705057 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03417076 0,10691136 ! catecholamine transport GO:0051937 9 6 0,000 0,03417076 0,10677252 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03417076 0,10663403 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03417076 0,10649591 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03417076 0,10635814 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03417076 0,10622072 ! maternal placenta development GO:0001893 12 6 0,000 0,03417076 0,10608366 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03417076 0,10594696 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03417076 0,1058106 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03417076 0,1056746 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03417076 0,10553895 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03417076 0,10540364 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03417076 0,10526868 ! positive regulation of binding GO:0051099 78 51 1,000 0,03517311 0,10821802 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03517311 0,10807981 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,03517311 0,10794196 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,03517311 0,10780445 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,03517311 0,10766729 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,03517311 0,10753049 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03644391 0,11127416 ! positive regulation of growth GO:0045927 90 52 1,000 0,03644391 0,11113313 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03644391 0,11099245 ! cartilage development GO:0051216 90 52 1,000 0,03644391 0,11085213 ! synapse organization GO:0050808 85 52 1,000 0,03644391 0,11071217 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,03773221 0,11448133 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,03773221 0,11433715 ! cell maturation GO:0048469 100 53 1,000 0,03773221 0,11419333 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,03773221 0,11404987 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03903778 0,11784805 GO:0010863|positive regulation of phospholipase C activity, ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 0,03903778 0,11770037 ! tRNA transcription GO:0009304 14 7 0,000 0,03975192 0,11970352 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03975192 0,11955389 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03975192 0,11940463 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03975192 0,11925575 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03975192 0,11910723 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03975192 0,11895909 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03975192 0,11881132 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03975192 0,11866391 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03975192 0,11851686 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03975192 0,11837018 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03975192 0,11822387 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03975192 0,11807791 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03975192 0,11793232 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03975192 0,11778708 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03975192 0,1176422 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03975192 0,11749768 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03975192 0,11735351 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03975192 0,11720969 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03975192 0,11706623 ! glycolipid transport GO:0046836 10 7 0,000 0,03975192 0,11692312 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03975192 0,11678035 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03975192 0,11663794 ! neuron adhesion GO:0007158 12 7 0,000 0,03975192 0,11649587 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03975192 0,11635415 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03975192 0,11621277 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03975192 0,11607173 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03975192 0,11593104 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03975192 0,11579069 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03975192 0,11565068 ! pericardium development GO:0060039 14 7 0,000 0,03975192 0,115511 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03975192 0,11537166 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03975192 0,11523266 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03975192 0,11509399 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03975192 0,11495566 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03975192 0,11481766 ! lipoprotein transport GO:0042953 14 7 0,000 0,03975192 0,11467999 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03975192 0,11454265 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03975192 0,11440563 ! rhythmic behavior GO:0007622 15 7 0,000 0,03975192 0,11426895 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03975192 0,11413259 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03975192 0,11399655 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03975192 0,11386084 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03975192 0,11372546 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03975192 0,11359039 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03975192 0,11345564 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03975192 0,11332122 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03975192 0,11318711 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03975192 0,11305332 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03975192 0,11291984 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03975192 0,11278668 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03975192 0,11265384 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03975192 0,1125213 ! spinal cord patterning GO:0021511 13 7 0,000 0,03975192 0,11238908 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03975192 0,11225717 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03975192 0,11212557 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03975192 0,11199427 ! adrenal gland development GO:0030325 17 7 0,000 0,03975192 0,11186329 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03975192 0,1117326 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03975192 0,11160223 ! ovulation GO:0030728 9 7 0,000 0,03975192 0,11147215 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03975192 0,11134238 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03975192 0,11121292 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03975192 0,11108375 ! microtubule nucleation GO:0007020 20 7 0,000 0,03975192 0,11095488 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03975192 0,11082631 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03975192 0,11069804 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03975192 0,11057007 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03975192 0,11044239 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03975192 0,110315 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03975192 0,11018791 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03975192 0,11006111 ! galactose metabolic process GO:0006012 13 7 0,000 0,03975192 0,10993461 ! vesicle fusion GO:0006906 17 7 0,000 0,03975192 0,10980839 ! response to dietary excess GO:0002021 8 7 0,000 0,03975192 0,10968246 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03975192 0,10955683 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03975192 0,10943147 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03975192 0,10930641 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03975192 0,10918163 ! organ growth GO:0035265 15 7 0,000 0,03975192 0,10905714 ! purine salvage GO:0043101 10 7 0,000 0,03975192 0,10893293 ! nucleoside transport GO:0015858 8 7 0,000 0,03975192 0,108809 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03975192 0,10868535 ! parturition GO:0007567 14 7 0,000 0,03975192 0,10856198 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03975192 0,1084389 ! rRNA modification GO:0000154 14 7 0,000 0,03975192 0,10831609 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03975192 0,10819356 ! spindle checkpoint GO:0031577 15 7 0,000 0,03975192 0,10807131 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03975192 0,10794933 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03975192 0,10782763 ! macrophage differentiation GO:0030225 11 7 0,000 0,03975192 0,1077062 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03975192 0,10758505 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03975192 0,10746417 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03975192 0,10734356 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03975192 0,10722322 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03975192 0,10710315 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03975192 0,10698334 ! fibrinolysis GO:0042730 10 7 0,000 0,03975192 0,10686381 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03975192 0,10674454 ! eating behavior GO:0042755 7 7 0,000 0,03975192 0,10662554 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03975192 0,1065068 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03975192 0,10638833 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03975192 0,10627012 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03975192 0,10615217 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03975192 0,10603449 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03975192 0,10591706 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03975192 0,1057999 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03975192 0,10568299 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03975192 0,10556635 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03975192 0,10544995 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03975192 0,10533382 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03975192 0,10521794 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03975192 0,10510232 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03975192 0,10498695 ! regulation of meiosis GO:0040020 12 7 0,000 0,03975192 0,10487183 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03975192 0,10475696 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03975192 0,10464235 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03975192 0,10452799 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03975192 0,10441387 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03975192 0,10430001 ! response to tumor cell GO:0002347 13 7 0,000 0,03975192 0,10418639 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03975192 0,10407302 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03975192 0,1039599 ! anaphase GO:0051322 17 7 0,000 0,03975192 0,10384702 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03975192 0,10373439 ! axonal fasciculation GO:0007413 18 7 0,000 0,03975192 0,103622 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03975192 0,10350986 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03975192 0,10339796 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03975192 0,10328629 ! diuresis GO:0030146 12 7 0,000 0,03975192 0,10317487 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03975192 0,10306369 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03975192 0,10295275 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03975192 0,10284205 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03975192 0,10273159 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03975192 0,10262136 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03975192 0,10251137 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03975192 0,10240162 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03975192 0,10229209 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03975192 0,10218281 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03975192 0,10207376 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03975192 0,10196493 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03975192 0,10185635 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03975192 0,10174799 ! lymph node development GO:0048535 10 7 0,000 0,03975192 0,10163986 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03975192 0,10153196 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03975192 0,10142429 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03975192 0,10131685 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03975192 0,10120964 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03975192 0,10110265 ! adult feeding behavior GO:0008343 9 7 0,000 0,03975192 0,10099589 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03975192 0,10088936 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03975192 0,10078304 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03975192 0,10067696 ! muscle adaptation GO:0043500 14 7 0,000 0,03975192 0,10057109 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03975192 0,10046545 ! retina homeostasis GO:0001895 12 7 0,000 0,03975192 0,10036003 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03975192 0,10025483 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03975192 0,10014985 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03975192 0,10004509 ! protein prenylation GO:0018342 18 7 0,000 0,03975192 0,09994055 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03975192 0,09983623 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03975192 0,09973213 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03975192 0,09962824 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,04036037 0,10104791 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04036037 0,10094287 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,04036037 0,10083805 ! aging GO:0007568 103 55 1,000 0,04036037 0,10073345 ! gastrulation GO:0007369 112 55 1,000 0,04036037 0,10062906 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,04036037 0,10052489 ! RNA elongation GO:0006354 79 55 1,000 0,04036037 0,10042094 ! regulation of actin filament length GO:0030832 105 56 1,000 0,04169974 0,10364626 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04169974 0,1035393 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04169974 0,10343256 ! muscle fiber development GO:0048747 112 57 1,000 0,04305567 0,10668583 ! lipid modification GO:0030258 97 57 1,000 0,04305567 0,10657607 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04305567 0,10646653 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,04305567 0,10635722 ! maintenance of location GO:0051235 118 57 1,000 0,04305567 0,10624814 ! regulation of endocytosis GO:0030100 91 58 1,000 0,04442791 0,10952208 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04442791 0,10940998 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04530101 0,11144604 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04530101 0,1113322 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04530101 0,1112186 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04530101 0,11110522 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04530101 0,11099208 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04530101 0,11087917 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04530101 0,11076649 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04530101 0,11065404 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04530101 0,11054181 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04530101 0,11042981 ! meiotic prophase I GO:0007128 13 8 0,000 0,04530101 0,11031804 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04530101 0,1102065 ! oligopeptide transport GO:0006857 15 8 0,000 0,04530101 0,11009518 ! UTP metabolic process GO:0046051 8 8 0,000 0,04530101 0,10998408 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04530101 0,10987321 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04530101 0,10976256 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04530101 0,10965214 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04530101 0,10954193 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04530101 0,10943195 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04530101 0,10932219 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04530101 0,10921265 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04530101 0,10910333 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04530101 0,10899422 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04530101 0,10888534 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04530101 0,10877667 ! reflex GO:0060004 16 8 0,000 0,04530101 0,10866822 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04530101 0,10855998 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04530101 0,10845196 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04530101 0,10834416 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04530101 0,10823657 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04530101 0,10812919 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04530101 0,10802203 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04530101 0,10791507 ! pigment granule organization GO:0048753 16 8 0,000 0,04530101 0,10780833 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04530101 0,1077018 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04530101 0,10759548 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04530101 0,10748937 ! histidine metabolic process GO:0006547 16 8 0,000 0,04530101 0,10738347 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04530101 0,10727778 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04530101 0,1071723 ! glycine catabolic process GO:0006546 13 8 0,000 0,04530101 0,10706702 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04530101 0,10696195 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04530101 0,10685708 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,04530101 0,10675242 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04530101 0,10664797 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04530101 0,10654372 ! melanin metabolic process GO:0006582 15 8 0,000 0,04530101 0,10643967 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04530101 0,10633583 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04530101 0,10623219 ! macrophage activation GO:0042116 12 8 0,000 0,04530101 0,10612875 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04530101 0,10602551 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04530101 0,10592247 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04530101 0,10581964 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04530101 0,105717 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04530101 0,10561456 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04530101 0,10551232 ! osteoblast development GO:0002076 16 8 0,000 0,04530101 0,10541028 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04530101 0,10530843 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04530101 0,10520678 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04530101 0,10510533 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04530101 0,10500407 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04530101 0,10490301 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04530101 0,10480214 ! response to UV-B GO:0010224 16 8 0,000 0,04530101 0,10470146 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04530101 0,10460098 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04530101 0,10450069 ! intermediate filament organization GO:0045109 12 8 0,000 0,04530101 0,1044006 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04530101 0,10430069 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04530101 0,10420098 ! cellular extravasation GO:0045123 12 8 0,000 0,04530101 0,10410146 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04530101 0,10400212 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04530101 0,10390298 ! response to antibiotic GO:0046677 11 8 0,000 0,04530101 0,10380402 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04530101 0,10370526 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04530101 0,10360668 ! DNA topological change GO:0006265 12 8 0,000 0,04530101 0,10350829 ! response to tropane GO:0014073 15 8 0,000 0,04530101 0,10341008 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04530101 0,10331206 ! melanosome transport GO:0032402 13 8 0,000 0,04530101 0,10321423 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04530101 0,10311658 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04530101 0,10301912 ! mast cell activation GO:0045576 14 8 0,000 0,04530101 0,10292184 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04530101 0,10282474 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04530101 0,10272783 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04530101 0,1026311 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04530101 0,10253455 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04530101 0,10243818 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04530101 0,10234199 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04530101 0,10224599 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04530101 0,10215016 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04530101 0,10205452 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04530101 0,10195905 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04530101 0,10186376 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04530101 0,10176865 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04530101 0,10167372 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04530101 0,10157896 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04530101 0,10148438 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04530101 0,10138998 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04530101 0,10129575 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04530101 0,10120169 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04530101 0,10110781 ! hormone catabolic process GO:0042447 17 8 0,000 0,04530101 0,10101411 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04530101 0,10092058 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04530101 0,10082722 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04530101 0,10073403 ! ATP catabolic process GO:0006200 11 8 0,000 0,04530101 0,10064102 ! blastocyst growth GO:0001832 19 8 0,000 0,04530101 0,10054818 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04530101 0,10045551 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04530101 0,10036301 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04530101 0,10027068 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04530101 0,10017852 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04530101 0,10008652 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04530101 0,0999947 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04530101 0,09990305 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04530101 0,09981156 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04530101 0,09972024 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04530101 0,09962909 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04530101 0,0995381 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04530101 0,09944729 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04530101 0,09935663 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04530101 0,09926614 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04530101 0,09917582 ! regulation of cellular component size GO:0032535 109 59 1,000 0,04581623 0,1002126 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04581623 0,10012158 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04581623 0,10003072 ! camera-type eye development GO:0043010 116 60 1,000 0,04722041 0,10300301 ! kidney development GO:0001822 122 60 1,000 0,04722041 0,10290971 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,04864022 0,10590803 ! mesoderm development GO:0007498 119 61 1,000 0,04864022 0,10581227 ! gonad development GO:0008406 98 62 1,000 0,05007543 0,10883604 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05081822 0,11035075 ! axon extension GO:0048675 15 9 0,000 0,05081822 0,11025124 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05081822 0,11015192 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05081822 0,11005277 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05081822 0,1099538 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05081822 0,10985501 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05081822 0,1097564 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05081822 0,10965796 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05081822 0,1095597 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05081822 0,10946162 ! phosphate transport GO:0006817 19 9 0,000 0,05081822 0,10936371 ! reproductive behavior GO:0019098 19 9 0,000 0,05081822 0,10926598 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05081822 0,10916842 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05081822 0,10907103 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05081822 0,10897382 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 0,000 0,05081822 0,10887678 ! RNA methylation GO:0001510 15 9 0,000 0,05081822 0,10877992 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05081822 0,10868322 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05081822 0,1085867 ! artery development GO:0060840 24 9 0,000 0,05081822 0,10849035 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05081822 0,10839417 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05081822 0,10829816 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05081822 0,10820233 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05081822 0,10810666 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05081822 0,10801116 ! chemosensory behavior GO:0007635 20 9 0,000 0,05081822 0,10791582 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05081822 0,10782066 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05081822 0,10772566 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05081822 0,10763083 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05081822 0,10753617 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05081822 0,10744168 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05081822 0,10734735 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05081822 0,10725318 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05081822 0,10715918 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05081822 0,10706535 ! protein targeting to ER GO:0045047 22 9 0,000 0,05081822 0,10697168 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05081822 0,10687817 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05081822 0,10678483 ! T cell selection GO:0045058 23 9 0,000 0,05081822 0,10669165 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05081822 0,10659863 ! endosome organization GO:0007032 17 9 0,000 0,05081822 0,10650577 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05081822 0,10641308 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05081822 0,10632055 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05081822 0,10622817 ! mannose metabolic process GO:0006013 13 9 0,000 0,05081822 0,10613596 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05081822 0,10604391 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05081822 0,10595202 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05081822 0,10586028 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05081822 0,10576871 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05081822 0,10567729 ! ruffle organization GO:0031529 15 9 0,000 0,05081822 0,10558603 ! retinol metabolic process GO:0042572 18 9 0,000 0,05081822 0,10549493 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05081822 0,10540399 ! behavioral fear response GO:0001662 22 9 0,000 0,05081822 0,1053132 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05081822 0,10522257 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05081822 0,1051321 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05081822 0,10504178 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05081822 0,10495161 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05081822 0,1048616 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05081822 0,10477175 ! segment specification GO:0007379 13 9 0,000 0,05081822 0,10468204 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05081822 0,1045925 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05081822 0,1045031 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05081822 0,10441386 ! response to amine stimulus GO:0014075 13 9 0,000 0,05081822 0,10432477 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05081822 0,10423583 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05081822 0,10414704 ! erythrocyte development GO:0048821 15 9 0,000 0,05081822 0,10405841 ! gas homeostasis GO:0033483 16 9 0,000 0,05081822 0,10396992 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05081822 0,10388159 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05081822 0,1037934 ! renal water homeostasis GO:0003091 14 9 0,000 0,05081822 0,10370537 ! postreplication repair GO:0006301 22 9 0,000 0,05081822 0,10361748 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05081822 0,10352974 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05081822 0,10344216 ! icosanoid secretion GO:0032309 15 9 0,000 0,05081822 0,10335471 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05081822 0,10326742 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05081822 0,10318028 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05081822 0,10309328 ! regulation of cell division GO:0051302 15 9 0,000 0,05081822 0,10300643 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05081822 0,10291972 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05081822 0,10283316 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05081822 0,10274675 ! sterol catabolic process GO:0016127 11 9 0,000 0,05081822 0,10266048 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05081822 0,10257435 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05081822 0,10248837 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05081822 0,10240254 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05081822 0,10231684 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05081822 0,10223129 ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05081822 0,10214589 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05081822 0,10206062 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05081822 0,1019755 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05081822 0,10189052 ! pigment granule transport GO:0051904 17 9 0,000 0,05081822 0,10180569 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05081822 0,10172099 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05081822 0,10163643 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05081822 0,10155202 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05081822 0,10146774 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05081822 0,10138361 ! mitochondrion localization GO:0051646 15 9 0,000 0,05081822 0,10129961 ! regulation of mitosis GO:0007088 105 63 1,000 0,05152583 0,10262511 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,05152583 0,10254023 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,05152583 0,10245549 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,05152583 0,10237088 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,05447127 0,10813355 GO:0035113|embryonic appendage morphogenesis, ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,05447127 0,10804441 ! germ cell development GO:0007281 118 65 1,000 0,05447127 0,10795541 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05596588 0,11082626 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,05596588 0,11073512 ! developmental maturation GO:0021700 116 66 1,000 0,05596588 0,11064413 ! cell projection assembly GO:0030031 120 66 1,000 0,05596588 0,11055329 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05630372 0,11112941 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05630372 0,11103832 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05630372 0,11094738 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05630372 0,11085659 ! synapsis GO:0007129 13 10 0,000 0,05630372 0,11076595 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05630372 0,11067545 ! N-glycan processing GO:0006491 20 10 0,000 0,05630372 0,11058511 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05630372 0,11049491 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05630372 0,11040485 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05630372 0,11031495 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05630372 0,11022519 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05630372 0,11013557 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05630372 0,11004611 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05630372 0,10995678 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05630372 0,1098676 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05630372 0,10977857 ! androgen metabolic process GO:0008209 17 10 0,000 0,05630372 0,10968968 ! phospholipid efflux GO:0033700 16 10 0,000 0,05630372 0,10960094 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05630372 0,10951233 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05630372 0,10942387 ! pathogenesis GO:0009405 13 10 0,000 0,05630372 0,10933556 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05630372 0,10924738 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05630372 0,10915935 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05630372 0,10907146 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05630372 0,10898371 ! endoderm development GO:0007492 16 10 0,000 0,05630372 0,10889611 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05630372 0,10880864 ! arginine catabolic process GO:0006527 13 10 0,000 0,05630372 0,10872131 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05630372 0,10863413 ! proline metabolic process GO:0006560 13 10 0,000 0,05630372 0,10854708 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05630372 0,10846017 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05630372 0,10837341 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05630372 0,10828678 ! V(D)J recombination GO:0033151 28 10 0,000 0,05630372 0,10820028 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05630372 0,10811393 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05630372 0,10802772 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05630372 0,10794164 ! B cell proliferation GO:0042100 18 10 0,000 0,05630372 0,1078557 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05630372 0,10776989 ! multicellular organism growth GO:0035264 18 10 0,000 0,05630372 0,10768423 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05630372 0,10759869 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05630372 0,1075133 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05630372 0,10742804 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05630372 0,10734291 ! macroautophagy GO:0016236 17 10 0,000 0,05630372 0,10725792 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05630372 0,10717307 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05630372 0,10708834 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05630372 0,10700376 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05630372 0,1069193 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05630372 0,10683498 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05630372 0,10675079 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05630372 0,10666674 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05630372 0,10658281 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05630372 0,10649902 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05630372 0,10641536 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05630372 0,10633183 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05630372 0,10624844 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05630372 0,10616517 ! response to dsRNA GO:0043331 20 10 0,000 0,05630372 0,10608203 ! DNA ligation GO:0006266 19 10 0,000 0,05630372 0,10599903 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05630372 0,10591615 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05630372 0,1058334 ! melanosome localization GO:0032400 16 10 0,000 0,05630372 0,10575079 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05630372 0,1056683 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05630372 0,10558594 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05630372 0,1055037 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05630372 0,1054216 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05630372 0,10533962 ! mRNA cleavage GO:0006379 17 10 0,000 0,05630372 0,10525777 ! protein sumoylation GO:0016925 15 10 0,000 0,05630372 0,10517605 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05630372 0,10509446 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05630372 0,10501299 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05630372 0,10493165 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05630372 0,10485043 ! salivary gland development GO:0007431 27 10 0,000 0,05630372 0,10476934 ! prophase GO:0051324 15 10 0,000 0,05630372 0,10468837 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05630372 0,10460753 ! apical protein localization GO:0045176 15 10 0,000 0,05630372 0,10452682 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05630372 0,10444623 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05630372 0,10436576 ! midbrain development GO:0030901 13 10 0,000 0,05630372 0,10428542 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05630372 0,1042052 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05630372 0,1041251 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05630372 0,10404513 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05630372 0,10396528 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05630372 0,10388555 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05630372 0,10380594 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05630372 0,10372646 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05630372 0,1036471 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05630372 0,10356786 ! oocyte development GO:0048599 17 10 0,000 0,05630372 0,10348874 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05630372 0,10340974 ! blastocyst formation GO:0001825 17 10 0,000 0,05630372 0,10333086 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05630372 0,1032521 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05630372 0,10317346 ! activation of innate immune response GO:0002218 12 10 0,000 0,05630372 0,10309494 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05630372 0,10301654 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05630372 0,10293826 ! response to nicotine GO:0035094 20 10 0,000 0,05630372 0,1028601 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05630372 0,10278206 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05630372 0,10270414 ! activation of MAPK activity GO:0000187 115 67 1,000 0,0574748 0,10476089 ! chromosome segregation GO:0007059 113 67 1,000 0,0574748 0,10468158 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,0574748 0,1046024 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,0574748 0,10452333 ! adaptive immune response GO:0002250 119 67 1,000 0,0574748 0,10444439 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,05899782 0,10713113 ! regulation of lipase activity GO:0060191 130 68 1,000 0,05899782 0,10705034 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,05899782 0,10696967 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06053472 0,10967359 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06053472 0,10959107 ! respiratory burst GO:0045730 17 11 0,000 0,06175771 0,11172109 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06175771 0,11163715 ! neuron fate specification GO:0048665 17 11 0,000 0,06175771 0,11155334 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06175771 0,11146965 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06175771 0,11138609 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,06175771 0,11130266 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06175771 0,11121935 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06175771 0,11113616 ! response to pain GO:0048265 24 11 0,000 0,06175771 0,1110531 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06175771 0,11097016 ! T cell proliferation GO:0042098 26 11 0,000 0,06175771 0,11088735 ! bone resorption GO:0045453 16 11 0,000 0,06175771 0,11080466 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06175771 0,11072209 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06175771 0,11063965 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06175771 0,11055733 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06175771 0,11047513 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06175771 0,11039305 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06175771 0,1103111 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06175771 0,11022926 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06175771 0,11014755 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06175771 0,11006596 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06175771 0,10998449 ! lipid digestion GO:0044241 18 11 0,000 0,06175771 0,10990314 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06175771 0,10982191 ! UV protection GO:0009650 19 11 0,000 0,06175771 0,1097408 ! adult heart development GO:0007512 14 11 0,000 0,06175771 0,10965981 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06175771 0,10957894 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06175771 0,10949819 ! temperature homeostasis GO:0001659 17 11 0,000 0,06175771 0,10941756 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06175771 0,10933705 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06175771 0,10925665 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06175771 0,10917638 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06175771 0,10909622 ! regulation of organ growth GO:0046620 13 11 0,000 0,06175771 0,10901617 ! pigment granule localization GO:0051875 20 11 0,000 0,06175771 0,10893625 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06175771 0,10885644 ! vasoconstriction GO:0042310 18 11 0,000 0,06175771 0,10877675 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06175771 0,10869718 ! embryonic axis specification GO:0000578 18 11 0,000 0,06175771 0,10861772 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06175771 0,10853838 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06175771 0,10845916 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06175771 0,10838005 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06175771 0,10830105 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06175771 0,10822218 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06175771 0,10814341 ! zymogen activation GO:0031638 15 11 0,000 0,06175771 0,10806476 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06175771 0,10798623 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06175771 0,1079078 ! nucleosome positioning GO:0016584 15 11 0,000 0,06175771 0,1078295 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06175771 0,1077513 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06175771 0,10767322 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06175771 0,10759525 ! acid secretion GO:0046717 18 11 0,000 0,06175771 0,1075174 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06175771 0,10743966 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06175771 0,10736203 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06175771 0,10728451 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06175771 0,1072071 ! oocyte differentiation GO:0009994 18 11 0,000 0,06175771 0,10712981 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06175771 0,10705263 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06175771 0,10697556 ! cholesterol efflux GO:0033344 19 11 0,000 0,06175771 0,10689859 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06175771 0,10682174 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06175771 0,106745 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06175771 0,10666838 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06175771 0,10659186 ! embryonic gut development GO:0048566 15 11 0,000 0,06175771 0,10651545 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06175771 0,10643914 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06175771 0,10636295 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06175771 0,10628687 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06175771 0,1062109 ! defense response to fungus GO:0050832 13 11 0,000 0,06175771 0,10613503 ! developmental induction GO:0031128 19 11 0,000 0,06175771 0,10605928 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06175771 0,10598363 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06175771 0,10590809 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06175771 0,10583265 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06175771 0,10575733 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06175771 0,10568211 ! nucleus localization GO:0051647 19 11 0,000 0,06175771 0,105607 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06175771 0,10553199 ! appendage morphogenesis GO:0035107 135 70 1,000 0,06208529 0,10601647 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,06364933 0,10861014 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 1,000 0,06522664 0,11122274 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06522664 0,11114397 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,06522664 0,11106531 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06522664 0,11098677 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,06522664 0,11090833 ! axon guidance GO:0007411 139 73 1,000 0,066817 0,11353227 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06718035 0,11406911 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06718035 0,11398867 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06718035 0,11390834 ! virus-host interaction GO:0019048 29 12 0,000 0,06718035 0,11382812 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06718035 0,11374802 ! mating GO:0007618 17 12 0,000 0,06718035 0,11366802 ! hippocampus development GO:0021766 26 12 0,000 0,06718035 0,11358815 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06718035 0,11350838 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06718035 0,11342872 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06718035 0,11334918 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06718035 0,11326975 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06718035 0,11319043 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06718035 0,11311122 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06718035 0,11303212 ! drug transport GO:0015893 16 12 0,000 0,06718035 0,11295313 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06718035 0,11287425 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06718035 0,11279549 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06718035 0,11271683 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06718035 0,11263828 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06718035 0,11255984 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06718035 0,11248151 ! forebrain cell migration GO:0021885 21 12 0,000 0,06718035 0,11240329 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06718035 0,11232518 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06718035 0,11224717 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06718035 0,11216928 ! entry into host cell GO:0030260 32 12 0,000 0,06718035 0,11209149 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06718035 0,11201381 ! monoamine transport GO:0015844 18 12 0,000 0,06718035 0,11193624 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06718035 0,11185878 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06718035 0,11178142 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06718035 0,11170417 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06718035 0,11162702 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06718035 0,11154999 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06718035 0,11147306 ! protein homotetramerization GO:0051289 21 12 0,000 0,06718035 0,11139623 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06718035 0,11131951 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06718035 0,1112429 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06718035 0,11116639 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06718035 0,11108999 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06718035 0,11101369 ! fucose catabolic process GO:0019317 22 12 0,000 0,06718035 0,1109375 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06718035 0,11086141 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06718035 0,11078542 ! gland morphogenesis GO:0022612 29 12 0,000 0,06718035 0,11070954 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06718035 0,11063377 ! T cell homeostasis GO:0043029 25 12 0,000 0,06718035 0,11055809 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06718035 0,11048252 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06718035 0,11040706 ! spleen development GO:0048536 22 12 0,000 0,06718035 0,11033169 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06718035 0,11025643 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06718035 0,11018128 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06718035 0,11010622 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06718035 0,11003127 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06718035 0,10995642 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06718035 0,10988167 ! response to cold GO:0009409 17 12 0,000 0,06718035 0,10980702 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06718035 0,10973247 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06718035 0,10965803 ! meiosis GO:0007126 121 74 1,000 0,06842022 0,11160613 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 1,000 0,06842022 0,11153052 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,06842022 0,11145501 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,06842022 0,1113796 ! organelle localization GO:0051640 136 74 1,000 0,06842022 0,11130429 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,0700361 0,11385598 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,0700361 0,1137791 ! meiotic cell cycle GO:0051321 122 75 1,000 0,0700361 0,11370232 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,0700361 0,11362565 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,07166443 0,1161891 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07257184 0,11758104 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07257184 0,11750191 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07257184 0,11742289 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07257184 0,11734398 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07257184 0,11726517 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07257184 0,11718647 ! lipid localization GO:0010876 28 13 0,000 0,07257184 0,11710787 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07257184 0,11702938 ! organelle fusion GO:0048284 32 13 0,000 0,07257184 0,116951 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07257184 0,11687272 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07257184 0,11679454 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07257184 0,11671647 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07257184 0,1166385 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07257184 0,11656064 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07257184 0,11648288 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07257184 0,11640523 ! methionine metabolic process GO:0006555 27 13 0,000 0,07257184 0,11632768 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07257184 0,11625023 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07257184 0,11617288 ! Golgi organization GO:0007030 24 13 0,000 0,07257184 0,11609564 ! response to X-ray GO:0010165 25 13 0,000 0,07257184 0,1160185 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07257184 0,11594146 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07257184 0,11586453 ! exocrine system development GO:0035272 32 13 0,000 0,07257184 0,11578769 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07257184 0,11571096 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07257184 0,11563433 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07257184 0,1155578 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07257184 0,11548138 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07257184 0,11540505 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07257184 0,11532882 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07257184 0,1152527 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07257184 0,11517668 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07257184 0,11510075 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07257184 0,11502493 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07257184 0,1149492 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07257184 0,11487358 ! ribosome assembly GO:0042255 17 13 0,000 0,07257184 0,11479805 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07257184 0,11472263 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07257184 0,1146473 ! chromatin silencing GO:0006342 26 13 0,000 0,07257184 0,11457207 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07257184 0,11449694 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07257184 0,11442191 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07257184 0,11434698 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07257184 0,11427215 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07257184 0,11419741 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07257184 0,11412277 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07257184 0,11404823 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07257184 0,11397379 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07257184 0,11389944 ! embryonic placenta development GO:0001892 23 13 0,000 0,07257184 0,11382519 ! insulin secretion GO:0030073 23 13 0,000 0,07257184 0,11375104 ! actin filament polymerization GO:0030041 24 13 0,000 0,07257184 0,11367698 ! acrosome reaction GO:0007340 18 13 0,000 0,07257184 0,11360302 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,07330503 0,11467614 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,07330503 0,11460163 ! blood coagulation GO:0007596 146 78 1,000 0,0749577 0,11710924 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,0749577 0,11703325 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,07662225 0,11955456 ! rRNA transcription GO:0009303 25 14 0,000 0,07793234 0,1215199 ! lactation GO:0007595 26 14 0,000 0,07793234 0,12144119 ! reproductive cellular process GO:0048610 20 14 0,000 0,07793234 0,12136259 ! tRNA modification GO:0006400 20 14 0,000 0,07793234 0,12128409 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07793234 0,12120569 ! regulation of S phase GO:0033261 23 14 0,000 0,07793234 0,12112739 ! water transport GO:0006833 21 14 0,000 0,07793234 0,1210492 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07793234 0,1209711 ! non-recombinational repair GO:0000726 25 14 0,000 0,07793234 0,1208931 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07793234 0,12081521 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07793234 0,12073741 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07793234 0,12065972 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07793234 0,12058213 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07793234 0,12050463 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07793234 0,12042723 ! palate development GO:0060021 31 14 0,000 0,07793234 0,12034994 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,07793234 0,12027274 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07793234 0,12019564 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07793234 0,12011864 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07793234 0,12004174 ! arginine metabolic process GO:0006525 17 14 0,000 0,07793234 0,11996494 ! regulation of heart rate GO:0002027 24 14 0,000 0,07793234 0,11988824 ! organic alcohol transport GO:0015850 29 14 0,000 0,07793234 0,11981163 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07793234 0,11973512 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07793234 0,11965871 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07793234 0,1195824 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07793234 0,11950619 ! L-amino acid transport GO:0015807 30 14 0,000 0,07793234 0,11943007 ! bone mineralization GO:0030282 17 14 0,000 0,07793234 0,11935404 ! stem cell development GO:0048864 43 14 0,000 0,07793234 0,11927812 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07793234 0,11920229 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07793234 0,11912656 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07793234 0,11905092 ! cerebellum development GO:0021549 21 14 0,000 0,07793234 0,11897538 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07793234 0,11889994 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07793234 0,11882459 ! response to gamma radiation GO:0010332 28 14 0,000 0,07793234 0,11874934 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07793234 0,11867418 ! cofactor transport GO:0051181 26 14 0,000 0,07793234 0,11859912 ! NADP metabolic process GO:0006739 24 14 0,000 0,07793234 0,11852415 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07793234 0,11844928 ! intestinal absorption GO:0050892 25 14 0,000 0,07793234 0,1183745 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07793234 0,11829981 ! oxygen transport GO:0015671 21 14 0,000 0,07793234 0,11822522 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07793234 0,11815073 ! male genitalia development GO:0030539 24 14 0,000 0,07793234 0,11807633 ! regulation of axon extension GO:0030516 37 14 0,000 0,07793234 0,11800202 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,07793234 0,1179278 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07793234 0,11785368 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,07829849 0,11833301 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,08168526 0,12337397 ! response to nutrient GO:0007584 125 82 1,000 0,08168526 0,12329657 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,08168526 0,12321927 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08326203 0,12551908 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08326203 0,12544048 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08326203 0,12536198 ! superoxide anion generation GO:0042554 20 15 0,000 0,08326203 0,12528358 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08326203 0,12520528 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08326203 0,12512708 ! copper ion transport GO:0006825 20 15 0,000 0,08326203 0,12504897 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08326203 0,12497096 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08326203 0,12489305 ! sulfate transport GO:0008272 23 15 0,000 0,08326203 0,12481523 ! response to cAMP GO:0051591 22 15 0,000 0,08326203 0,12473751 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08326203 0,12465989 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08326203 0,12458237 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08326203 0,12450494 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08326203 0,12442761 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08326203 0,12435037 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08326203 0,12427323 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08326203 0,12419619 ! pituitary gland development GO:0021983 29 15 0,000 0,08326203 0,12411924 ! vesicle coating GO:0006901 33 15 0,000 0,08326203 0,12404238 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08326203 0,12396562 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08326203 0,12388896 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08326203 0,12381239 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08326203 0,12373592 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08326203 0,12365954 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08326203 0,12358325 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08326203 0,12350706 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08326203 0,12343096 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08326203 0,12335496 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08326203 0,12327904 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08326203 0,12320323 ! tissue regeneration GO:0042246 26 15 0,000 0,08326203 0,1231275 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08326203 0,12305187 ! water homeostasis GO:0030104 27 15 0,000 0,08326203 0,12297633 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08326203 0,12290089 ! muscle maintenance GO:0046716 26 15 0,000 0,08326203 0,12282554 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08326203 0,12275027 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08326203 0,12267511 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08326203 0,12260003 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08326203 0,12252504 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08326203 0,12245015 ! cell killing GO:0001906 29 15 0,000 0,08326203 0,12237535 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,08326203 0,12230064 ! detection of bacterium GO:0016045 18 15 0,000 0,08326203 0,12222602 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08326203 0,12215149 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08326203 0,12207706 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08326203 0,12200271 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08326203 0,12192845 ! peptide hormone processing GO:0016486 23 15 0,000 0,08326203 0,12185429 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08339543 0,12197532 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,08511654 0,12441701 ! hemostasis GO:0007599 158 84 1,000 0,08511654 0,12434147 ! negative regulation of transport GO:0051051 153 84 1,000 0,08511654 0,12426602 ! response to unfolded protein GO:0006986 131 85 1,000 0,08684842 0,12671758 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08856109 0,12913818 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08856109 0,12905996 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08856109 0,12898184 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08856109 0,12890381 ! bone remodeling GO:0046849 27 16 0,000 0,08856109 0,12882587 ! filopodium assembly GO:0046847 32 16 0,000 0,08856109 0,12874803 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,08856109 0,12867029 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08856109 0,12859263 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08856109 0,12851508 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08856109 0,12843761 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08856109 0,12836024 ! startle response GO:0001964 28 16 0,000 0,08856109 0,12828296 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08856109 0,12820577 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08856109 0,12812868 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08856109 0,12805168 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08856109 0,12797477 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08856109 0,12789796 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08856109 0,12782123 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08856109 0,1277446 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08856109 0,12766806 ! response to osmotic stress GO:0006970 25 16 0,000 0,08856109 0,12759161 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08856109 0,12751526 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08856109 0,12743899 ! fructose metabolic process GO:0006000 25 16 0,000 0,08856109 0,12736282 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08856109 0,12728674 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08856109 0,12721074 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08856109 0,12713484 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08856109 0,12705903 ! axon cargo transport GO:0008088 43 16 0,000 0,08856109 0,12698331 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08856109 0,12690768 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08856109 0,12683214 ! neuron recognition GO:0008038 35 16 0,000 0,08856109 0,12675669 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08856109 0,12668133 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08856109 0,12660606 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08856109 0,12653088 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08856109 0,12645578 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08856109 0,12638078 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08856109 0,12630587 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08856109 0,12623104 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08856109 0,1261563 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08856109 0,12608165 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08856109 0,12600709 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08856109 0,12593262 ! defense response to virus GO:0051607 37 16 0,000 0,08856109 0,12585824 ! mitochondrion organization GO:0007005 148 86 1,000 0,08859087 0,12582623 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,09034373 0,12824012 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 1,000 0,09034373 0,12816451 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,09210681 0,13058867 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0938297 0,13295304 ! metencephalon development GO:0022037 30 17 0,000 0,0938297 0,13287479 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0938297 0,13279663 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0938297 0,13271856 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0938297 0,13264058 ! endothelial cell migration GO:0043542 28 17 0,000 0,0938297 0,13256269 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0938297 0,1324849 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0938297 0,13240719 ! glial cell development GO:0021782 27 17 0,000 0,0938297 0,13232958 ! limbic system development GO:0021761 36 17 0,000 0,0938297 0,13225206 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0938297 0,13217463 ! adult walking behavior GO:0007628 33 17 0,000 0,0938297 0,13209729 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0938297 0,13202004 ! heart looping GO:0001947 30 17 0,000 0,0938297 0,13194288 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0938297 0,13186581 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0938297 0,13178883 ! myoblast differentiation GO:0045445 45 17 0,000 0,0938297 0,13171194 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0938297 0,13163514 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,0938297 0,13155843 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0938297 0,13148181 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0938297 0,13140528 ! glycine metabolic process GO:0006544 28 17 0,000 0,0938297 0,13132883 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0938297 0,13125248 ! NAD metabolic process GO:0019674 29 17 0,000 0,0938297 0,13117621 ! membrane budding GO:0006900 37 17 0,000 0,0938297 0,13110004 ! DNA integration GO:0015074 29 17 0,000 0,0938297 0,13102395 ! regulation of protein binding GO:0043393 33 17 0,000 0,0938297 0,13094795 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0938297 0,13087204 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0938297 0,13079621 ! genitalia development GO:0048806 30 17 0,000 0,0938297 0,13072048 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0938297 0,13064483 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0938297 0,13056927 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,0938297 0,13049379 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0938297 0,13041841 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0938297 0,13034311 ! steroid catabolic process GO:0006706 31 17 0,000 0,0938297 0,1302679 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0938297 0,13019277 ! gas transport GO:0015669 25 17 0,000 0,0938297 0,13011773 ! organic cation transport GO:0015695 31 17 0,000 0,0938297 0,13004278 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0938297 0,12996791 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0938297 0,12989313 ! microspike assembly GO:0030035 36 17 0,000 0,0938297 0,12981844 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0938297 0,12974383 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0938297 0,12966931 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,09566295 0,1321269 ! sex differentiation GO:0007548 145 90 1,000 0,09566295 0,13205109 ! response to protein stimulus GO:0051789 149 91 1,000 0,09745566 0,13444858 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09906803 0,13659466 ! neuron maturation GO:0042551 42 18 0,000 0,09906803 0,13651643 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09906803 0,13643828 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09906803 0,13636023 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09906803 0,13628226 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09906803 0,13620439 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09906803 0,1361266 ! memory GO:0007613 31 18 0,000 0,09906803 0,1360489 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09906803 0,13597129 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09906803 0,13589377 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09906803 0,13581634 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09906803 0,135739 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09906803 0,13566174 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09906803 0,13558457 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09906803 0,13550749 ! response to retinoic acid GO:0032526 26 18 0,000 0,09906803 0,1354305 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,09906803 0,13535359 ! response to fungus GO:0009620 21 18 0,000 0,09906803 0,13527678 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09906803 0,13520004 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09906803 0,1351234 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09906803 0,13504684 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09906803 0,13497037 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09906803 0,13489399 ! vitamin transport GO:0051180 27 18 0,000 0,09906803 0,13481769 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09906803 0,13474148 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09906803 0,13466536 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09906803 0,13458932 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09906803 0,13451336 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,09906803 0,1344375 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09906803 0,13436171 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09906803 0,13428602 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,10106953 0,1369219 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,10106953 0,13684485 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,10106953 0,13676788 ! protein secretion GO:0009306 39 19 0,000 0,10427625 0,14102791 ! positive regulation of translation GO:0045727 30 19 0,000 0,10427625 0,14094868 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10427625 0,14086954 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10427625 0,14079049 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10427625 0,14071153 ! skin development GO:0043588 36 19 0,000 0,10427625 0,14063265 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10427625 0,14055387 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10427625 0,14047517 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10427625 0,14039656 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10427625 0,14031804 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10427625 0,1402396 ! cerebral cortex development GO:0021987 36 19 0,000 0,10427625 0,14016126 ! pigmentation during development GO:0048066 41 19 0,000 0,10427625 0,140083 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10427625 0,14000483 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10427625 0,13992674 ! heme metabolic process GO:0042168 36 19 0,000 0,10427625 0,13984875 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10427625 0,13977084 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10427625 0,13969301 ! peptide cross-linking GO:0018149 37 19 0,000 0,10427625 0,13961528 ! protein export from nucleus GO:0006611 36 19 0,000 0,10427625 0,13953763 ! heart process GO:0003015 30 19 0,000 0,10427625 0,13946006 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10427625 0,13938258 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10427625 0,13930519 ! visual learning GO:0008542 36 19 0,000 0,10427625 0,13922789 ! cellular pigmentation GO:0033059 36 19 0,000 0,10427625 0,13915067 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10427625 0,13907353 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10427625 0,13899648 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10427625 0,13891952 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10427625 0,13884264 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10427625 0,13876585 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10427625 0,13868914 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10427625 0,13861252 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10427625 0,13853598 ! cilium assembly GO:0042384 37 19 0,000 0,10427625 0,13845952 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10427625 0,13838315 ! forebrain development GO:0030900 188 95 1,000 0,1047202 0,1388957 ! leukocyte differentiation GO:0002521 202 96 1,000 0,10655893 0,14125663 ! hormone metabolic process GO:0042445 157 97 1,000 0,10840636 0,14362649 ! regulation of protein localization GO:0032880 176 97 1,000 0,10840636 0,14354744 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10945453 0,14485567 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10945453 0,14477603 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10945453 0,14469648 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10945453 0,14461702 ! response to vitamin GO:0033273 31 20 0,000 0,10945453 0,14453765 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10945453 0,14445836 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,10945453 0,14437917 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10945453 0,14430005 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10945453 0,14422103 ! response to alkaloid GO:0043279 38 20 0,000 0,10945453 0,14414209 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10945453 0,14406324 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10945453 0,14398447 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10945453 0,14390579 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10945453 0,1438272 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10945453 0,14374869 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10945453 0,14367027 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10945453 0,14359193 ! body fluid secretion GO:0007589 31 20 0,000 0,10945453 0,14351368 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10945453 0,14343551 ! peptide secretion GO:0002790 35 20 0,000 0,10945453 0,14335743 ! stem cell differentiation GO:0048863 53 20 0,000 0,10945453 0,14327943 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10945453 0,14320152 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10945453 0,1431237 ! sensory perception of pain GO:0019233 30 20 0,000 0,10945453 0,14304595 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10945453 0,14296829 ! diencephalon development GO:0021536 34 20 0,000 0,10945453 0,14289072 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10945453 0,14281323 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10945453 0,14273583 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10945453 0,1426585 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,10945453 0,14258127 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10945453 0,14250411 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10945453 0,14242704 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10945453 0,14235005 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10945453 0,14227315 ! regulation of glucose import GO:0046324 29 20 0,000 0,10945453 0,14219633 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10945453 0,14211959 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10945453 0,14204293 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10945453 0,14196636 ! negative regulation of translation GO:0017148 29 20 0,000 0,10945453 0,14188987 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10945453 0,14181346 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,10945453 0,14173714 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,11212672 0,14511936 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,11212672 0,14504134 ! regulation of cell killing GO:0031341 42 21 0,000 0,11460305 0,14816493 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11460305 0,14808535 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11460305 0,14800587 ! hormone secretion GO:0046879 38 21 0,000 0,11460305 0,14792646 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11460305 0,14784715 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11460305 0,14776792 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11460305 0,14768877 ! axis specification GO:0009798 38 21 0,000 0,11460305 0,14760971 ! ovarian follicle development GO:0001541 35 21 0,000 0,11460305 0,14753073 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,11460305 0,14745183 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11460305 0,14737303 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11460305 0,1472943 ! cell aging GO:0007569 44 21 0,000 0,11460305 0,14721566 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11460305 0,1471371 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11460305 0,14705863 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11460305 0,14698024 ! cytolysis GO:0019835 24 21 0,000 0,11460305 0,14690193 ! vasodilation GO:0042311 39 21 0,000 0,11460305 0,14682371 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11460305 0,14674557 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11460305 0,14666752 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11460305 0,14658954 ! oogenesis GO:0048477 36 21 0,000 0,11460305 0,14651165 ! DNA modification GO:0006304 34 21 0,000 0,11460305 0,14643385 ! collagen fibril organization GO:0030199 59 21 0,000 0,11460305 0,14635612 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11460305 0,14627848 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11460305 0,14620092 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11460305 0,14612344 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,11460305 0,14604604 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11460305 0,14596873 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11460305 0,1458915 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11460305 0,14581435 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11460305 0,14573728 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11460305 0,14566029 ! collagen catabolic process GO:0030574 28 21 0,000 0,11460305 0,14558338 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11460305 0,14550656 ! gut development GO:0048565 39 21 0,000 0,11460305 0,14542982 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,11972197 0,15184558 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11972197 0,15176557 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11972197 0,15168565 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11972197 0,15160582 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11972197 0,15152607 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11972197 0,1514464 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11972197 0,15136682 ! regeneration GO:0031099 41 22 0,000 0,11972197 0,15128732 ! keratinization GO:0031424 28 22 0,000 0,11972197 0,1512079 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11972197 0,15112857 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11972197 0,15104932 ! sensory perception of taste GO:0050909 28 22 0,000 0,11972197 0,15097016 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,11972197 0,15089107 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11972197 0,15081207 ! vacuolar transport GO:0007034 36 22 0,000 0,11972197 0,15073315 ! lysosome organization GO:0007040 41 22 0,000 0,11972197 0,15065432 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11972197 0,15057557 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11972197 0,15049689 ! fucose metabolic process GO:0006004 39 22 0,000 0,11972197 0,15041831 ! ureteric bud development GO:0001657 43 22 0,000 0,11972197 0,1503398 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11972197 0,15026138 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,11972197 0,15018303 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11972197 0,15010477 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,11972197 0,15002659 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11972197 0,14994849 ! sarcomere organization GO:0045214 30 22 0,000 0,11972197 0,14987048 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11972197 0,14979254 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11972197 0,14971469 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11972197 0,14963691 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11972197 0,14955922 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,12481146 0,15583621 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,12481146 0,15575539 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12481146 0,15567464 ! gluconeogenesis GO:0006094 33 23 0,000 0,12481146 0,15559398 ! viral genome replication GO:0019079 41 23 0,000 0,12481146 0,1555134 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12481146 0,15543291 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12481146 0,1553525 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12481146 0,15527217 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12481146 0,15519193 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12481146 0,15511177 ! visual behavior GO:0007632 42 23 0,000 0,12481146 0,15503169 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12481146 0,15495169 ! response to ethanol GO:0045471 46 23 0,000 0,12481146 0,15487178 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12481146 0,15479195 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,12481146 0,1547122 ! peroxisome organization GO:0007031 37 23 0,000 0,12481146 0,15463254 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12481146 0,15455295 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12481146 0,15447345 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12481146 0,15439403 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12481146 0,15431469 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,12481146 0,15423543 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12481146 0,15415625 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12481146 0,15407716 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12481146 0,15399815 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12481146 0,15391921 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12481146 0,15384036 ! platelet activation GO:0030168 37 23 0,000 0,12481146 0,15376159 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12481146 0,1536829 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12481146 0,15360429 ! hormone transport GO:0009914 40 23 0,000 0,12481146 0,15352576 ! cell-cell recognition GO:0009988 25 23 0,000 0,12481146 0,15344731 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12481146 0,15336894 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12481146 0,15329065 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12481146 0,15321244 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12481146 0,15313431 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,1298717 0,15926163 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1298717 0,1591805 GO:0016444|somatic cell DNA recombination, ! spinal cord development GO:0021510 47 24 0,000 0,1298717 0,15909945 ! vacuole organization GO:0007033 43 24 0,000 0,1298717 0,15901848 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,1298717 0,1589376 ! digestive system process GO:0022600 39 24 0,000 0,1298717 0,1588568 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,1298717 0,15877608 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,1298717 0,15869544 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,1298717 0,15861488 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,1298717 0,15853441 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,1298717 0,15845401 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1298717 0,1583737 ! membrane depolarization GO:0051899 39 24 0,000 0,1298717 0,15829347 ! pallium development GO:0021543 49 24 0,000 0,1298717 0,15821332 ! pentose metabolic process GO:0019321 35 24 0,000 0,1298717 0,15813326 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,1298717 0,15805327 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1298717 0,15797337 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1298717 0,15789354 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1298717 0,1578138 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1298717 0,15773413 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1298717 0,15765455 ! regulation of amine transport GO:0051952 40 24 0,000 0,1298717 0,15757505 ! protein tetramerization GO:0051262 52 24 0,000 0,1298717 0,15749562 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13490285 0,16351449 ! phototransduction GO:0007602 33 25 0,000 0,13490285 0,16343215 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,13490285 0,1633499 ! sperm motility GO:0030317 31 25 0,000 0,13490285 0,16326774 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13490285 0,16318565 ! chromosome condensation GO:0030261 45 25 0,000 0,13490285 0,16310365 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13490285 0,16302173 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,13490285 0,16293989 ! neural crest cell development GO:0014032 54 25 0,000 0,13490285 0,16285813 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13490285 0,16277646 ! negative regulation of cell development GO:0010721 73 25 0,000 0,13490285 0,16269487 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13490285 0,16261336 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13490285 0,16253193 ! interaction with host GO:0051701 62 25 0,000 0,13490285 0,16245058 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13490285 0,16236931 ! immunoglobulin production GO:0002377 55 25 0,000 0,13490285 0,16228813 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13490285 0,16220703 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13490285 0,162126 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13490285 0,16204506 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13490285 0,1619642 ! telomere organization GO:0032200 43 25 0,000 0,13490285 0,16188342 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,13490285 0,16180272 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13990507 0,16771879 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13990507 0,16763526 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13990507 0,16755182 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13990507 0,16746846 ! initiation of viral infection GO:0019059 57 26 0,000 0,13990507 0,16738518 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13990507 0,16730199 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13990507 0,16721888 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13990507 0,16713585 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13990507 0,16705291 ! molting cycle process GO:0022404 50 26 0,000 0,13990507 0,16697004 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13990507 0,16688726 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13990507 0,16680456 GO:0051297|centrosome organization, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,13990507 0,16672194 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13990507 0,16663941 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13990507 0,16655696 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13990507 0,16647458 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13990507 0,16639229 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13990507 0,16631008 ! blastocyst development GO:0001824 49 26 0,000 0,13990507 0,16622795 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13990507 0,16614591 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13990507 0,16606394 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13990507 0,16598205 ! neuron fate commitment GO:0048663 48 27 0,000 0,14487854 0,17179781 ! iron ion transport GO:0006826 59 27 0,000 0,14487854 0,17171318 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14487854 0,17162864 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14487854 0,17154417 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14487854 0,17145979 ! fat cell differentiation GO:0045444 50 27 0,000 0,14487854 0,1713755 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14487854 0,17129128 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14487854 0,17120715 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14487854 0,1711231 ! autophagy GO:0006914 41 27 0,000 0,14487854 0,17103914 ! response to toxin GO:0009636 47 27 0,000 0,14487854 0,17095525 ! base-excision repair GO:0006284 41 27 0,000 0,14487854 0,17087145 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14487854 0,17078773 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14487854 0,17070409 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14487854 0,17062054 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14487854 0,17053707 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,14487854 0,17045367 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14487854 0,17037036 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14982341 0,17609923 ! circadian rhythm GO:0007623 50 28 0,000 0,14982341 0,17601324 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14982341 0,17592734 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,14982341 0,17584152 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,14982341 0,17575579 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14982341 0,17567014 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,14982341 0,17558457 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14982341 0,17549908 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14982341 0,17541368 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14982341 0,17532837 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14982341 0,17524313 ! synaptogenesis GO:0007416 42 28 0,000 0,14982341 0,17515798 ! lipid oxidation GO:0034440 43 28 0,000 0,14982341 0,17507291 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14982341 0,17498792 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14982341 0,17490302 ! translational initiation GO:0006413 65 29 0,000 0,15473985 0,18055484 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15473985 0,18046731 ! regulation of pH GO:0006885 43 29 0,000 0,15473985 0,18037988 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,15473985 0,18029253 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15473985 0,18020526 ! catechol metabolic process GO:0009712 54 29 0,000 0,15473985 0,18011808 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15473985 0,18003098 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15473985 0,17994397 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15473985 0,17985704 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15473985 0,17977019 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15473985 0,17968343 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,15473985 0,17959675 ! cell fate determination GO:0001709 60 29 0,000 0,15473985 0,17951016 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15473985 0,17942365 ! detection of light stimulus GO:0009583 38 29 0,000 0,15473985 0,17933722 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,15473985 0,17925088 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15473985 0,17916462 ! tissue homeostasis GO:0001894 48 29 0,000 0,15473985 0,17907844 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,15473985 0,17899234 ! phenol metabolic process GO:0018958 55 30 0,000 0,15962802 0,18455791 ! zinc ion transport GO:0006829 45 30 0,000 0,15962802 0,18446926 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,15962802 0,1843807 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15962802 0,18429223 ! acute-phase response GO:0006953 49 30 0,000 0,15962802 0,18420384 ! myofibril assembly GO:0030239 47 30 0,000 0,15962802 0,18411554 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,15962802 0,18402732 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15962802 0,18393918 ! phospholipid transport GO:0015914 51 30 0,000 0,15962802 0,18385113 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15962802 0,18376316 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,15962802 0,18367528 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15962802 0,18358748 ! eye morphogenesis GO:0048592 60 30 0,000 0,15962802 0,18349977 ! response to heat GO:0009408 50 30 0,000 0,15962802 0,18341213 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16448808 0,18890612 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16448808 0,18881599 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16448808 0,18872595 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16448808 0,188636 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16448808 0,18854613 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16448808 0,18845634 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16448808 0,18836664 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16448808 0,18827703 ! ovulation cycle process GO:0022602 49 31 0,000 0,16448808 0,1881875 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16448808 0,18809806 ! peptide transport GO:0015833 55 31 0,000 0,16448808 0,1880087 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16448808 0,18791943 ! iron ion homeostasis GO:0055072 54 31 0,000 0,16448808 0,18783024 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16448808 0,18774114 ! natural killer cell activation GO:0030101 45 31 0,000 0,16448808 0,18765212 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16448808 0,18756319 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16448808 0,18747433 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16448808 0,18738557 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16448808 0,18729689 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,1693202 0,19270785 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,1693202 0,19261673 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1693202 0,19252571 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1693202 0,19243476 ! cholesterol transport GO:0030301 56 32 0,000 0,1693202 0,19234391 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1693202 0,19225314 ! spliceosome assembly GO:0000245 67 32 0,000 0,1693202 0,19216245 ! response to ionizing radiation GO:0010212 65 32 0,000 0,1693202 0,19207185 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,1693202 0,19198134 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,1693202 0,19189091 ! muscle cell development GO:0055001 49 32 0,000 0,1693202 0,19180056 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1693202 0,1917103 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1693202 0,19162013 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,1693202 0,19153004 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,1693202 0,19144003 ! ovulation cycle GO:0042698 51 32 0,000 0,1693202 0,19135011 ! BMP signaling pathway GO:0030509 64 32 0,000 0,1693202 0,19126028 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,1693202 0,19117053 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1693202 0,19108086 ! gene silencing GO:0016458 65 32 0,000 0,1693202 0,19099128 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,17412453 0,19631847 ! post-embryonic development GO:0009791 69 33 0,000 0,17412453 0,19622652 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17412453 0,19613465 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17412453 0,19604287 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17412453 0,19595118 ! sterol transport GO:0015918 57 33 0,000 0,17412453 0,19585957 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,17412453 0,19576804 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17412453 0,19567661 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17412453 0,19558525 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17412453 0,19549399 ! glial cell differentiation GO:0010001 63 34 0,000 0,17890123 0,20076323 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,17890123 0,20066963 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17890123 0,20057612 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,17890123 0,2004827 ! mismatch repair GO:0006298 46 34 0,000 0,17890123 0,20038937 ! spermatid development GO:0007286 63 34 0,000 0,17890123 0,20029612 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17890123 0,20020296 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17890123 0,20010988 ! placenta development GO:0001890 53 34 0,000 0,17890123 0,2000169 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,17890123 0,19992399 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18365046 0,20513603 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18365046 0,20504084 ! odontogenesis GO:0042476 66 35 0,000 0,18365046 0,20494574 ! female gonad development GO:0008585 58 35 0,000 0,18365046 0,20485073 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18365046 0,2047558 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,18365046 0,20466096 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,18365046 0,20456621 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,18365046 0,20447155 ! vesicle localization GO:0051648 64 35 0,000 0,18365046 0,20437697 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18837238 0,20953489 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18837238 0,20943806 ! positive regulation of cell development GO:0010720 80 36 0,000 0,18837238 0,20934132 ! regulation of proteolysis GO:0030162 72 36 0,000 0,18837238 0,20924467 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18837238 0,20914811 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18837238 0,20905164 ! aerobic respiration GO:0009060 55 36 0,000 0,18837238 0,20895526 ! embryonic organ development GO:0048568 57 36 0,000 0,18837238 0,20885897 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18837238 0,20876276 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19306715 0,2138672 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19306715 0,21376878 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19306715 0,21367045 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19306715 0,21357221 ! organic anion transport GO:0015711 68 37 0,000 0,19306715 0,21347406 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19306715 0,213376 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19306715 0,21327804 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19306715 0,21318016 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19306715 0,21308237 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,19306715 0,21298467 ! spermatid differentiation GO:0048515 66 37 0,000 0,19306715 0,21288706 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19773491 0,21793413 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,19773491 0,21783434 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19773491 0,21773464 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,19773491 0,21763504 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19773491 0,21753553 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,19773491 0,21743611 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,19773491 0,21733677 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,19773491 0,21723753 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,19773491 0,21713838 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,19773491 0,21703932 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,19773491 0,21694036 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,19773491 0,21684148 ! glucan metabolic process GO:0044042 62 38 0,000 0,19773491 0,21674269 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,20237583 0,22172871 ! learning GO:0007612 77 39 0,000 0,20237583 0,22162778 ! ear morphogenesis GO:0042471 60 39 0,000 0,20237583 0,22152695 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20237583 0,22142621 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20237583 0,22132557 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20237583 0,22122501 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,20237583 0,22112454 ! RNA modification GO:0009451 57 39 0,000 0,20237583 0,22102417 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20237583 0,22092389 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,20699005 0,22585853 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20699005 0,22575615 ! feeding behavior GO:0007631 59 40 0,000 0,20699005 0,22565386 ! mesenchymal cell development GO:0014031 87 40 0,000 0,20699005 0,22555166 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,20699005 0,22544955 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21157773 0,23034209 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,21157773 0,23023791 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21157773 0,23013383 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21157773 0,23002984 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,21157773 0,22992594 ! female gamete generation GO:0007292 61 41 0,000 0,21157773 0,22982214 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,21613903 0,2346708 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,21613903 0,23456495 ! regulation of tube size GO:0035150 71 42 0,000 0,21613903 0,2344592 GO:0050880|regulation of blood vessel size, ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,21613903 0,23435354 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21613903 0,23424797 ! regulation of protein secretion GO:0050708 71 42 0,000 0,21613903 0,2341425 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,22067408 0,23894773 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22067408 0,23884024 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22067408 0,23873284 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,22067408 0,23862555 ! glucose transport GO:0015758 65 43 0,000 0,22067408 0,23851835 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22067408 0,23841125 ! striated muscle contraction GO:0006941 77 43 0,000 0,22067408 0,23830424 ! phagocytosis GO:0006909 90 43 0,000 0,22067408 0,23819733 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22067408 0,23809051 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22518305 0,24284645 ! hexose transport GO:0008645 67 44 0,000 0,22518305 0,24273765 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,22518305 0,24262894 ! double-strand break repair GO:0006302 81 44 0,000 0,22518305 0,24252033 ! B cell differentiation GO:0030183 107 44 0,000 0,22518305 0,24241182 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22518305 0,24230341 ! glycolysis GO:0006096 65 45 0,000 0,22966608 0,24701681 ! leukocyte migration GO:0050900 68 45 0,000 0,22966608 0,24690643 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,22966608 0,24679616 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22966608 0,24668598 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22966608 0,2465759 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22966608 0,24646592 ! cell growth GO:0016049 84 45 0,000 0,22966608 0,24635604 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23412332 0,25102527 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,23412332 0,25091346 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,23412332 0,25080174 ! pigmentation GO:0043473 100 46 0,000 0,23412332 0,25069013 ! positive regulation of defense response GO:0031349 76 47 0,000 0,23855492 0,25532168 ! response to calcium ion GO:0051592 81 47 0,000 0,23855492 0,25520815 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,23855492 0,25509473 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,23855492 0,2549814 ! JNK cascade GO:0007254 91 47 0,000 0,23855492 0,25486818 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,23855492 0,25475505 ! protein homooligomerization GO:0051260 76 47 0,000 0,23855492 0,25464203 ! mitochondrial transport GO:0006839 82 48 0,000 0,24296102 0,25923025 ! Notch signaling pathway GO:0007219 96 48 0,000 0,24296102 0,25911534 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,24296102 0,25900054 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24296102 0,25888583 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24296102 0,25877123 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,24296102 0,25865673 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24734177 0,26320402 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,24734177 0,26308766 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,24734177 0,26297141 ! regulation of ion transport GO:0043269 77 49 0,000 0,24734177 0,26285525 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,24734177 0,2627392 ! peptide metabolic process GO:0006518 76 49 0,000 0,24734177 0,26262326 ! response to temperature stimulus GO:0009266 76 49 0,000 0,24734177 0,26250741 ! endocrine system development GO:0035270 104 49 0,000 0,24734177 0,26239167 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24734177 0,26227602 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24734177 0,26216048 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,24734177 0,26204504 ! inner ear development GO:0048839 79 50 0,000 0,25169731 0,26654214 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,25169731 0,26642487 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,25169731 0,26630771 ! viral infectious cycle GO:0019058 99 51 0,000 0,2560278 0,2707705 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,2560278 0,27065153 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,2560278 0,27053267 ! excretion GO:0007588 83 51 0,000 0,2560278 0,27041391 ! vesicle organization GO:0016050 107 51 0,000 0,2560278 0,27029525 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,26033336 0,27472021 ! membrane fusion GO:0006944 110 52 0,000 0,26033336 0,27459977 ! amino acid activation GO:0043038 92 52 0,000 0,26033336 0,27447944 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26461416 0,27887064 ! RNA catabolic process GO:0006401 93 53 0,000 0,26461416 0,27874854 ! regulation of translational initiation GO:0006446 82 53 0,000 0,26461416 0,27862655 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26461416 0,27850466 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,26461416 0,27838289 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,26887031 0,28273688 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,26887031 0,28261336 ! cell recognition GO:0008037 85 54 0,000 0,26887031 0,28248995 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,26887031 0,28236664 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,26887031 0,28224345 ! chloride transport GO:0006821 90 55 0,000 0,27310198 0,28656056 ! glucose catabolic process GO:0006007 82 55 0,000 0,27310198 0,28643564 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,27310198 0,28631083 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27310198 0,28618613 ! heart morphogenesis GO:0003007 97 55 0,000 0,27310198 0,28606154 ! nuclear export GO:0051168 97 55 0,000 0,27310198 0,28593706 ! sensory perception of smell GO:0007608 80 56 0,000 0,27730929 0,29021582 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27730929 0,29008963 ! proton transport GO:0015992 94 56 0,000 0,27730929 0,28996356 ! hydrogen transport GO:0006818 97 58 0,000 0,28565142 0,29855661 ! adult behavior GO:0030534 99 58 0,000 0,28565142 0,29842697 ! positive regulation of secretion GO:0051047 95 59 0,000 0,28978651 0,3026156 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28978651 0,30248431 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,28978651 0,30235314 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,2938978 0,3065098 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,2938978 0,306377 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,2938978 0,30624431 ! regulation of heart contraction GO:0008016 110 60 0,000 0,2938978 0,30611173 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,2938978 0,30597928 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,29798543 0,31010075 ! tRNA processing GO:0008033 89 61 0,000 0,29798543 0,30996668 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,29798543 0,30983273 ! ear development GO:0043583 103 62 0,000 0,30204952 0,31392274 ! viral reproductive process GO:0022415 126 62 0,000 0,30204952 0,3137872 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,30204952 0,31365177 ! detection of external stimulus GO:0009581 91 63 0,000 0,30609023 0,31771057 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,30609023 0,31757356 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,31010767 0,32160304 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31010767 0,32146448 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,31010767 0,32132604 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,31010767 0,32118772 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,31010767 0,32104951 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,31410199 0,3250449 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,31410199 0,32490516 ! extracellular matrix organization GO:0030198 133 66 0,000 0,31807332 0,32887168 ! secondary metabolic process GO:0019748 116 66 0,000 0,31807332 0,32873041 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,32202178 0,33266827 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,32202178 0,33252549 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,32202178 0,33238284 ! hexose catabolic process GO:0019320 104 67 0,000 0,32202178 0,33224031 ! activation of immune response GO:0002253 105 67 0,000 0,32202178 0,3320979 ! amino acid transport GO:0006865 125 68 0,000 0,32594751 0,33600245 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,32594751 0,33585855 ! viral reproduction GO:0016032 134 68 0,000 0,32594751 0,33571477 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,32594751 0,33557112 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,32985064 0,33944424 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,32985064 0,33929912 ! antigen processing and presentation GO:0019882 104 69 0,000 0,32985064 0,33915412 ! amine catabolic process GO:0009310 117 71 0,000 0,33758961 0,34696309 ! humoral immune response GO:0006959 109 71 0,000 0,33758961 0,34681495 ! B cell activation GO:0042113 160 71 0,000 0,33758961 0,34666692 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,33758961 0,34651903 ! regulation of immune effector process GO:0002697 137 71 0,000 0,33758961 0,34637126 ! acute inflammatory response GO:0002526 113 72 0,000 0,34142571 0,35015782 ! carbohydrate transport GO:0008643 110 72 0,000 0,34142571 0,35000863 ! regulation of blood pressure GO:0008217 125 73 0,000 0,34523972 0,35376779 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,34523972 0,35361718 ! fertilization GO:0009566 90 73 0,000 0,34523972 0,35346671 ! transition metal ion transport GO:0000041 126 74 0,000 0,34903177 0,35719712 ! neurotransmitter transport GO:0006836 123 74 0,000 0,34903177 0,35704525 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,34903177 0,35689351 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,35280198 0,3605954 ! rhythmic process GO:0048511 128 75 0,000 0,35280198 0,36044228 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,35655048 0,36411734 ! defense response to bacterium GO:0042742 89 76 0,000 0,35655048 0,36396286 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,35655048 0,3638085 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,35655048 0,36365428 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36027739 0,36729975 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,36398284 0,37092025 ! protein oligomerization GO:0051259 139 78 0,000 0,36398284 0,37076322 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,36766695 0,37435747 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,36766695 0,37419911 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,36766695 0,37404088 ! response to metal ion GO:0010038 140 80 0,000 0,37132985 0,37760761 ! muscle cell differentiation GO:0042692 159 80 0,000 0,37132985 0,37744808 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,37132985 0,37728869 ! protein import into nucleus GO:0006606 158 80 0,000 0,37132985 0,37712943 ! inorganic anion transport GO:0015698 138 80 0,000 0,37132985 0,3769703 ! digestion GO:0007586 112 81 0,000 0,37497164 0,38050686 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,37497164 0,38034645 ! nuclear import GO:0051170 161 81 0,000 0,37497164 0,38018616 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,37497164 0,38002602 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,37859246 0,38353409 ! response to drug GO:0042493 143 82 0,000 0,37859246 0,38337267 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,38577165 0,39047816 ! amine biosynthetic process GO:0009309 138 86 0,000 0,39286837 0,39749424 ! response to inorganic substance GO:0010035 153 86 0,000 0,39286837 0,39732716 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,39286837 0,39716021 ! alcohol catabolic process GO:0046164 130 86 0,000 0,39286837 0,39699341 ! amine transport GO:0015837 155 86 0,000 0,39286837 0,39682674 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,3963861 0,4002119 ! protein localization in nucleus GO:0034504 176 87 0,000 0,3963861 0,40004403 ! cellular respiration GO:0045333 135 88 0,000 0,39988356 0,40340455 ! regulation of neurological system process GO:0031644 148 88 0,000 0,39988356 0,40323548 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39988356 0,40306655 ! cellular defense response GO:0006968 114 89 0,000 0,40336088 0,40640129 ! sterol metabolic process GO:0016125 152 91 0,000 0,41025552 0,41317488 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41025552 0,413002 ! regulation of defense response GO:0031347 149 92 0,000 0,41367308 0,41626826 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,41367308 0,41609424 ! vitamin metabolic process GO:0006766 139 92 0,000 0,41367308 0,41592036 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,41707094 0,41916152 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,42044923 0,42238031 ! female pregnancy GO:0007565 164 94 0,000 0,42044923 0,42220402 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,42380805 0,42539931 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,42714751 0,42857252 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,42714751 0,42839388 ! positive regulation of immune response GO:0050778 156 96 0,000 0,42714751 0,42821538 ! detection of stimulus GO:0051606 151 96 0,000 0,42714751 0,42803703 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,43046773 0,43118458 ! protein ubiquitination GO:0016567 217 97 0,000 0,43046773 0,43100514 ! response to virus GO:0009615 160 98 0,000 0,43376882 0,43412969 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,43376882 0,43394918 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,43376882 0,43376882 GO:0016054|organic acid catabolic process,