pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6581-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of intracellular protein transport GO:0033157 25 25 5,000 8,65E-08 1,594E-04 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 5,000 1,425E-07 1,313E-04 ! regulation of cell migration GO:0030334 71 71 7,000 2,716E-07 1,668E-04 ! skeletal system morphogenesis GO:0048705 31 30 5,000 2,795E-07 1,288E-04 ! regulation of intracellular transport GO:0032386 31 31 5,000 3,441E-07 1,268E-04 ! embryonic skeletal system morphogenesis GO:0048704 17 17 4,000 3,651E-07 1,121E-04 ! regulation of angiogenesis GO:0045765 35 34 5,000 6,147E-07 1,618E-04 ! regulation of locomotion GO:0040012 79 79 7,000 6,275E-07 1,446E-04 ! regulation of cell motion GO:0051270 79 79 7,000 6,275E-07 1,285E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 3,000 8,826E-07 1,627E-04 ! embryonic skeletal system development GO:0048706 22 22 4,000 1,498E-06 2,51E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 3,000 2,279E-06 3,5E-04 GO:0032388|positive regulation of intracellular transport, ! regulation of protein transport GO:0051223 53 53 5,000 9,121E-06 1,293E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of protein localization GO:0032880 58 57 5,000 1,4E-05 1,843E-03 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 6,000 1,443E-05 1,773E-03 ! heart development GO:0007507 90 87 6,000 1,558E-05 1,794E-03 ! ER overload response GO:0006983 6 6 2,000 1,578E-05 1,711E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 4,000 1,68E-05 1,72E-03 ! positive regulation of cell migration GO:0030335 36 36 4,000 1,937E-05 1,878E-03 ! negative regulation of growth GO:0045926 37 37 4,000 2,223E-05 2,048E-03 ! metanephros development GO:0001656 19 19 3,000 2,529E-05 2,219E-03 ! dorsal/ventral pattern formation GO:0009953 19 19 3,000 2,529E-05 2,118E-03 ! pattern specification process GO:0007389 96 94 6,000 2,591E-05 2,076E-03 ! cranial nerve development GO:0021545 7 7 2,000 2,742E-05 2,106E-03 ! regulation of mRNA stability GO:0043488 7 7 2,000 2,742E-05 2,022E-03 ! positive regulation of cell motion GO:0051272 39 39 4,000 2,894E-05 2,051E-03 ! positive regulation of gene-specific transcription GO:0043193 20 20 3,000 3,138E-05 2,142E-03 ! striated muscle tissue development GO:0014706 69 67 5,000 3,576E-05 2,354E-03 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 3,000 3,85E-05 2,446E-03 ! regulation of protein import into nucleus GO:0042306 21 21 3,000 3,85E-05 2,365E-03 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 6,000 3,875E-05 2,304E-03 ! regionalization GO:0003002 70 69 5,000 4,233E-05 2,438E-03 ! thyroid gland development GO:0030878 8 8 2,000 4,358E-05 2,434E-03 ! regulation of RNA stability GO:0043487 8 8 2,000 4,358E-05 2,362E-03 ! muscle tissue development GO:0060537 72 70 5,000 4,596E-05 2,42E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 3,000 4,672E-05 2,392E-03 ! protein import into nucleus GO:0006606 44 44 4,000 5,263E-05 2,622E-03 ! nuclear import GO:0051170 45 45 4,000 5,878E-05 2,851E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 2,000 6,493E-05 3,069E-03 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 2,000 6,493E-05 2,992E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 2,000 6,493E-05 2,919E-03 GO:0060675|ureteric bud morphogenesis, ! positive regulation of protein import into nucleus GO:0042307 9 9 2,000 6,493E-05 2,849E-03 ! regulation of gene-specific transcription GO:0032583 25 25 3,000 7,909E-05 3,39E-03 ! protein localization in nucleus GO:0034504 48 48 4,000 8,061E-05 3,376E-03 ! gland development GO:0048732 51 49 4,000 8,912E-05 3,65E-03 ! cell cycle arrest GO:0007050 49 49 4,000 8,912E-05 3,57E-03 ! nuclear transport GO:0051169 79 79 5,000 9,118E-05 3,575E-03 GO:0006913|nucleocytoplasmic transport, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 2,000 9,214E-05 3,538E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 9,214E-05 3,465E-03 ! nerve development GO:0021675 10 10 2,000 9,214E-05 3,396E-03 ! anterior/posterior pattern formation GO:0009952 51 50 4,000 9,83E-05 3,552E-03 ! tube development GO:0035295 83 81 5,000 1,049E-04 3,718E-03 ! blood vessel morphogenesis GO:0048514 84 83 5,000 1,202E-04 4,18E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 1,253E-04 4,277E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 2,000 1,258E-04 4,217E-03 ! regulation of monooxygenase activity GO:0032768 11 11 2,000 1,258E-04 4,141E-03 ! negative regulation of angiogenesis GO:0016525 11 11 2,000 1,258E-04 4,069E-03 ! regulation of cellular localization GO:0060341 86 85 5,000 1,373E-04 4,362E-03 ! positive regulation of protein transport GO:0051222 29 29 3,000 1,443E-04 4,509E-03 ! heterophilic cell adhesion GO:0007157 12 12 2,000 1,666E-04 5,119E-03 ! collagen metabolic process GO:0032963 12 12 2,000 1,666E-04 5,035E-03 ! extracellular structure organization GO:0043062 56 56 4,000 1,697E-04 5,043E-03 ! brain development GO:0007420 91 90 5,000 1,883E-04 5,51E-03 ! negative regulation of cell cycle GO:0045786 92 91 5,000 2,002E-04 5,764E-03 ! negative regulation of cell growth GO:0030308 32 32 3,000 2,139E-04 6,066E-03 ! kidney development GO:0001822 32 32 3,000 2,139E-04 5,974E-03 ! ureteric bud development GO:0001657 13 13 2,000 2,152E-04 5,919E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 2,000 2,152E-04 5,832E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 2,000 2,152E-04 5,748E-03 ! negative regulation of intracellular transport GO:0032387 13 13 2,000 2,152E-04 5,665E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 2,000 2,152E-04 5,586E-03 ! negative regulation of DNA replication GO:0008156 13 13 2,000 2,152E-04 5,508E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 2,000 2,152E-04 5,433E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 2,152E-04 5,359E-03 ! protein localization in organelle GO:0033365 59 59 4,000 2,176E-04 5,347E-03 ! blood vessel development GO:0001568 95 94 5,000 2,392E-04 5,8E-03 ! negative regulation of cell size GO:0045792 33 33 3,000 2,417E-04 5,786E-03 ! vasculature development GO:0001944 97 96 5,000 2,683E-04 6,34E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 2,72E-04 6,346E-03 ! response to retinoic acid GO:0032526 14 14 2,000 2,72E-04 6,267E-03 GO:0033189|response to vitamin A, ! protein import GO:0017038 62 62 4,000 2,752E-04 6,261E-03 ! angiogenesis GO:0001525 65 64 4,000 3,195E-04 7,182E-03 ! muscle organ development GO:0007517 102 100 5,000 3,35E-04 7,439E-03 ! protein import into nucleus, translocation GO:0000060 15 15 2,000 3,377E-04 7,41E-03 ! response to vitamin GO:0033273 15 15 2,000 3,377E-04 7,323E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 3,377E-04 7,238E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 3,377E-04 7,155E-03 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 2,000 3,377E-04 7,073E-03 ! protein homooligomerization GO:0051260 15 15 2,000 3,377E-04 6,994E-03 ! meiosis GO:0007126 37 37 3,000 3,792E-04 7,766E-03 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 3,000 3,792E-04 7,681E-03 ! cell fate specification GO:0001708 16 16 2,000 4,129E-04 8,271E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 4,129E-04 8,182E-03 ! cell-matrix adhesion GO:0007160 39 38 3,000 4,209E-04 8,252E-03 ! urogenital system development GO:0001655 38 38 3,000 4,209E-04 8,165E-03 ! meiotic cell cycle GO:0051321 38 38 3,000 4,209E-04 8,08E-03 ! respiratory tube development GO:0030323 40 39 3,000 4,657E-04 8,848E-03 ! respiratory system development GO:0060541 40 39 3,000 4,657E-04 8,757E-03 ! protein oligomerization GO:0051259 39 39 3,000 4,657E-04 8,669E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 4,98E-04 9,178E-03 ! cell junction assembly GO:0034329 18 17 2,000 4,98E-04 9,087E-03 ! tissue remodeling GO:0048771 17 17 2,000 4,98E-04 8,998E-03 ! regulation of oxidoreductase activity GO:0051341 17 17 2,000 4,98E-04 8,91E-03 ! embryonic organ development GO:0048568 17 17 2,000 4,98E-04 8,825E-03 ! negative regulation of signal transduction GO:0009968 71 71 4,000 5,186E-04 9,103E-03 ! meiosis I GO:0007127 18 18 2,000 5,935E-04 0,01031991 ! cell-substrate adhesion GO:0031589 43 42 3,000 6,204E-04 0,01068557 ! forebrain development GO:0030900 43 42 3,000 6,204E-04 0,01058663 ! negative regulation of DNA metabolic process GO:0051053 19 19 2,000 7,001E-04 0,01183743 ! regulation of endothelial cell proliferation GO:0001936 19 19 2,000 7,001E-04 0,01172982 ! multicellular organismal metabolic process GO:0044236 19 19 2,000 7,001E-04 0,01162414 ! cellular response to oxidative stress GO:0034599 19 19 2,000 7,001E-04 0,01152036 ! negative regulation of cell communication GO:0010648 76 76 4,000 7,097E-04 0,01157569 ! neuron fate specification GO:0048665 5 5 1,000 8,63E-04 0,01395163 ! hemoglobin biosynthetic process GO:0042541 5 5 1,000 8,63E-04 0,01383031 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 8,63E-04 0,01371109 ! forebrain regionalization GO:0021871 5 5 1,000 8,63E-04 0,0135939 ! mRNA stabilization GO:0048255 5 5 1,000 8,63E-04 0,01347869 GO:0043489|RNA stabilization, ! memory GO:0007613 5 5 1,000 8,63E-04 0,01336543 ! middle ear morphogenesis GO:0042474 5 5 1,000 8,63E-04 0,01325405 ! heart looping GO:0001947 5 5 1,000 8,63E-04 0,01314451 ! muscle cell migration GO:0014812 5 5 1,000 8,63E-04 0,01303677 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 8,63E-04 0,01293078 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 1,000 8,63E-04 0,0128265 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 8,63E-04 0,01272389 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 8,63E-04 0,0126229 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 8,63E-04 0,01252351 ! positive regulation of monooxygenase activity GO:0032770 5 5 1,000 8,63E-04 0,01242567 ! spinal cord motor neuron differentiation GO:0021522 5 5 1,000 8,63E-04 0,01232935 GO:0021517|ventral spinal cord development, ! DNA methylation GO:0006306 5 5 1,000 8,63E-04 0,01223451 GO:0006305|DNA alkylation, ! T cell lineage commitment GO:0002360 5 5 1,000 8,63E-04 0,01214111 ! regulation of hormone metabolic process GO:0032350 5 5 1,000 8,63E-04 0,01204914 ! peptidyl-lysine modification GO:0018205 5 5 1,000 8,63E-04 0,01195854 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 8,63E-04 0,0118693 ! positive regulation of erythrocyte differentiation GO:0045648 5 5 1,000 8,63E-04 0,01178138 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 8,63E-04 0,01169475 GO:0007439|ectodermal gut development, ! embryonic gut development GO:0048566 5 5 1,000 8,63E-04 0,01160939 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 8,63E-04 0,01152526 ! embryonic heart tube development GO:0035050 5 5 1,000 8,63E-04 0,01144235 ! mammary gland development GO:0030879 23 21 2,000 9,48E-04 0,01248028 ! ear morphogenesis GO:0042471 21 21 2,000 9,48E-04 0,01239177 ! negative regulation of protein transport GO:0051224 21 21 2,000 9,48E-04 0,0123045 ! cell junction organization GO:0034330 23 22 2,000 1,09E-03 0,01405262 ! skeletal muscle tissue development GO:0007519 50 49 3,000 1,118E-03 0,01430442 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 1,118E-03 0,01420577 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 1,206E-03 0,01522739 ! endocrine system development GO:0035270 23 23 2,000 1,245E-03 0,01561517 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,287E-03 0,01602155 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of lipid kinase activity GO:0043550 6 6 1,000 1,287E-03 0,01591402 ! cartilage condensation GO:0001502 7 6 1,000 1,287E-03 0,01580793 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 1,287E-03 0,01570324 GO:0050927|positive regulation of positive chemotaxis, ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 1,287E-03 0,01559993 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 1,287E-03 0,01549797 ! oligodendrocyte differentiation GO:0048709 6 6 1,000 1,287E-03 0,01539733 ! focal adhesion formation GO:0048041 7 6 1,000 1,287E-03 0,015298 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,287E-03 0,01519993 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 1,287E-03 0,01510312 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 1,287E-03 0,01500753 ! regulation of bone resorption GO:0045124 6 6 1,000 1,287E-03 0,01491314 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,287E-03 0,01481993 ! DNA unwinding during replication GO:0006268 6 6 1,000 1,287E-03 0,01472789 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,287E-03 0,01463697 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 1,287E-03 0,01454718 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 1,287E-03 0,01445847 ! thymus development GO:0048538 6 6 1,000 1,287E-03 0,01437085 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,287E-03 0,01428427 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! localization within membrane GO:0051668 6 6 1,000 1,287E-03 0,01419874 ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 1,3E-03 0,01425855 GO:0051325|interphase, ! cell fate commitment GO:0045165 52 52 3,000 1,398E-03 0,01524736 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 1,414E-03 0,01532785 ! epithelial tube morphogenesis GO:0060562 25 24 2,000 1,414E-03 0,01523821 ! response to hypoxia GO:0001666 53 53 3,000 1,502E-03 0,01609044 ! DNA replication GO:0006260 91 91 4,000 1,603E-03 0,01707341 ! protein amino acid dephosphorylation GO:0006470 55 54 3,000 1,61E-03 0,01705716 ! response to oxygen levels GO:0070482 55 54 3,000 1,61E-03 0,01695969 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,79E-03 0,01874686 ! regulation of chemokine production GO:0032642 7 7 1,000 1,79E-03 0,01864095 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 1,79E-03 0,01853622 GO:0000725|recombinational repair, ! axis specification GO:0009798 7 7 1,000 1,79E-03 0,01843267 ! digestive system development GO:0055123 7 7 1,000 1,79E-03 0,01833027 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 1,000 1,79E-03 0,01822899 ! cell differentiation in spinal cord GO:0021515 7 7 1,000 1,79E-03 0,01812883 ! regulation of mRNA processing GO:0050684 7 7 1,000 1,79E-03 0,01802977 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,79E-03 0,01793178 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 1,000 1,79E-03 0,01783485 ! response to X-ray GO:0010165 7 7 1,000 1,79E-03 0,01773897 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,79E-03 0,01764411 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,79E-03 0,01755025 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! induction of an organ GO:0001759 7 7 1,000 1,79E-03 0,0174574 ! autonomic nervous system development GO:0048483 7 7 1,000 1,79E-03 0,01736551 ! response to gamma radiation GO:0010332 8 7 1,000 1,79E-03 0,0172746 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 1,79E-03 0,01718462 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 1,79E-03 0,01709558 GO:0001953|negative regulation of cell-matrix adhesion, ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,79E-03 0,01700746 ! negative regulation of cell migration GO:0030336 26 26 2,000 1,792E-03 0,01693594 ! double-strand break repair GO:0006302 27 26 2,000 1,792E-03 0,01684953 ! synapse organization GO:0050808 26 26 2,000 1,792E-03 0,016764 ! regulation of cell growth GO:0001558 97 96 4,000 2,032E-03 0,01891097 ! posttranscriptional regulation of gene expression GO:0010608 98 98 4,000 2,225E-03 0,02060505 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 2,000 2,228E-03 0,02052768 GO:0007254|JNK cascade, ! cartilage development GO:0051216 29 28 2,000 2,228E-03 0,02042555 ! dephosphorylation GO:0016311 60 59 3,000 2,237E-03 0,02041239 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 2,372E-03 0,02153935 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 2,372E-03 0,02143377 ! DNA duplex unwinding GO:0032508 8 8 1,000 2,372E-03 0,02132921 GO:0032392|DNA geometric change, ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 2,372E-03 0,02122567 ! plasma membrane fusion GO:0045026 8 8 1,000 2,372E-03 0,02112313 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 2,372E-03 0,02102158 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 2,372E-03 0,020921 ! peptidyl-serine modification GO:0018209 8 8 1,000 2,372E-03 0,02082138 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 2,372E-03 0,0207227 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 2,372E-03 0,02062495 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 2,372E-03 0,02052812 ! developmental induction GO:0031128 8 8 1,000 2,372E-03 0,02043219 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 2,372E-03 0,02033716 ! positive regulation of cell cycle GO:0045787 29 29 2,000 2,468E-03 0,02105814 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 2,468E-03 0,0209611 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 2,468E-03 0,02086495 ! DNA-dependent DNA replication GO:0006261 29 29 2,000 2,468E-03 0,02076967 ! response to UV GO:0009411 29 29 2,000 2,468E-03 0,02067526 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 3,000 2,529E-03 0,02109364 ! morphogenesis of an epithelium GO:0002009 63 62 3,000 2,685E-03 0,02228926 GO:0060429|epithelium development, ! skeletal muscle fiber development GO:0048741 31 31 2,000 2,996E-03 0,02475664 ! aging GO:0007568 32 31 2,000 2,996E-03 0,02464612 ! regulation of DNA replication GO:0006275 32 31 2,000 2,996E-03 0,02453658 ! extracellular matrix organization GO:0030198 31 31 2,000 2,996E-03 0,02442802 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 2,996E-03 0,0243204 ! negative regulation of cell motion GO:0051271 31 31 2,000 2,996E-03 0,02421373 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 3,032E-03 0,02439991 ! RNA polyadenylation GO:0043631 9 9 1,000 3,032E-03 0,02429382 GO:0006378|mRNA polyadenylation, ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 3,032E-03 0,02418865 ! regulation of cellular pH GO:0030641 9 9 1,000 3,032E-03 0,02408439 ! histone acetylation GO:0016573 9 9 1,000 3,032E-03 0,02398102 ! positive regulation of oxidoreductase activity GO:0051353 9 9 1,000 3,032E-03 0,02387854 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 3,032E-03 0,02377693 ! regulation of leukocyte migration GO:0002685 9 9 1,000 3,032E-03 0,02367618 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 3,032E-03 0,02357628 ! muscle fiber development GO:0048747 32 32 2,000 3,283E-03 0,0254246 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 3,283E-03 0,02531822 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 3,283E-03 0,02521273 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 3,372E-03 0,02579027 ! negative regulation of cell differentiation GO:0045596 68 67 3,000 3,561E-03 0,02712292 ! regulation of cell size GO:0008361 68 68 3,000 3,758E-03 0,02849834 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 3,767E-03 0,02845091 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 3,767E-03 0,02833478 ! inositol metabolic process GO:0006020 10 10 1,000 3,767E-03 0,0282196 ! transcription from RNA polymerase III promoter GO:0006383 10 10 1,000 3,767E-03 0,02810535 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 3,767E-03 0,02799202 ! neuromuscular junction development GO:0007528 10 10 1,000 3,767E-03 0,0278796 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 3,767E-03 0,02776809 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 3,767E-03 0,02765746 ! gut development GO:0048565 10 10 1,000 3,767E-03 0,0275477 ! embryonic organ morphogenesis GO:0048562 10 10 1,000 3,767E-03 0,02743882 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 3,767E-03 0,02733079 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 3,767E-03 0,02722361 ! mRNA 3'-end processing GO:0031124 10 10 1,000 3,767E-03 0,02711727 ! ear development GO:0043583 34 34 2,000 3,908E-03 0,02802696 ! response to nutrient levels GO:0031667 69 69 3,000 3,961E-03 0,02829357 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 3,961E-03 0,02818433 ! positive regulation of transport GO:0051050 71 70 3,000 4,171E-03 0,02956887 ! wound healing GO:0042060 74 70 3,000 4,171E-03 0,02945558 ! endothelial cell migration GO:0043542 11 11 1,000 4,576E-03 0,03218762 ! protein amino acid acetylation GO:0006473 11 11 1,000 4,576E-03 0,03206523 ! spinal cord development GO:0021510 11 11 1,000 4,576E-03 0,03194378 ! cellular response to starvation GO:0009267 11 11 1,000 4,576E-03 0,03182323 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 4,576E-03 0,0317036 ! G1/S transition checkpoint GO:0031575 12 11 1,000 4,576E-03 0,03158486 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 4,576E-03 0,031467 GO:0006109|regulation of carbohydrate metabolic process, ! muscle maintenance GO:0046716 12 11 1,000 4,576E-03 0,03135003 ! hindbrain development GO:0030902 11 11 1,000 4,576E-03 0,03123391 ! proximal/distal pattern formation GO:0009954 11 11 1,000 4,576E-03 0,03111866 ! RNA 3'-end processing GO:0031123 11 11 1,000 4,576E-03 0,03100425 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 4,576E-03 0,03089068 ! regulation of mitosis GO:0007088 37 36 2,000 4,601E-03 0,03094836 GO:0051783|regulation of nuclear division, ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 4,601E-03 0,03083583 ! sensory organ development GO:0007423 72 72 3,000 4,615E-03 0,03081777 ! response to extracellular stimulus GO:0009991 72 72 3,000 4,615E-03 0,03070651 ! response to drug GO:0042493 37 37 2,000 4,974E-03 0,03297267 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 5,364E-03 0,03543229 ! regulation of homeostatic process GO:0032844 38 38 2,000 5,364E-03 0,03530575 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 5,458E-03 0,03579488 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 5,458E-03 0,03566795 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 5,458E-03 0,03554191 ! regulation of chromosome organization GO:0033044 12 12 1,000 5,458E-03 0,03541677 ! somitogenesis GO:0001756 13 12 1,000 5,458E-03 0,0352925 ! G1 phase GO:0051318 13 12 1,000 5,458E-03 0,0351691 ! synaptogenesis GO:0007416 12 12 1,000 5,458E-03 0,03504656 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 5,458E-03 0,03492487 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 5,458E-03 0,03480402 ! nucleotide-excision repair GO:0006289 40 39 2,000 5,772E-03 0,03668239 ! regulation of protein modification process GO:0031399 79 78 3,000 6,135E-03 0,03885449 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 6,198E-03 0,0391221 ! vasculogenesis GO:0001570 13 13 1,000 6,411E-03 0,0403244 ! mitochondrial membrane organization GO:0007006 13 13 1,000 6,411E-03 0,04018724 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 6,411E-03 0,04005102 ! actin filament bundle formation GO:0051017 13 13 1,000 6,411E-03 0,03991571 ! cell aging GO:0007569 13 13 1,000 6,411E-03 0,03978131 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 6,411E-03 0,03964782 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 6,411E-03 0,03951522 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 6,411E-03 0,0393835 ! negative regulation of phosphorylation GO:0042326 13 13 1,000 6,411E-03 0,03925266 ! positive regulation of locomotion GO:0040017 13 13 1,000 6,411E-03 0,03912268 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 1,000 6,411E-03 0,03899356 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 6,411E-03 0,0388653 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 6,411E-03 0,03873787 GO:0001952|regulation of cell-matrix adhesion, ! activation of JUN kinase activity GO:0007257 13 13 1,000 6,411E-03 0,03861127 ! camera-type eye morphogenesis GO:0048593 13 13 1,000 6,411E-03 0,0384855 ! tissue homeostasis GO:0001894 13 13 1,000 6,411E-03 0,03836055 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 6,411E-03 0,03823641 ! cell cycle checkpoint GO:0000075 42 41 2,000 6,643E-03 0,03949443 ! regulation of caspase activity GO:0043281 41 41 2,000 6,643E-03 0,03936744 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 7,106E-03 0,04197793 ! neuron fate commitment GO:0048663 14 14 1,000 7,434E-03 0,04377211 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 7,434E-03 0,0436327 ! protein amino acid acylation GO:0043543 14 14 1,000 7,434E-03 0,04349419 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 7,434E-03 0,04335655 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 7,434E-03 0,04321978 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of behavior GO:0050795 14 14 1,000 7,434E-03 0,04308386 ! base-excision repair GO:0006284 14 14 1,000 7,434E-03 0,04294881 ! DNA modification GO:0006304 14 14 1,000 7,434E-03 0,04281459 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 8,089E-03 0,04644488 ! mRNA transport GO:0051028 44 44 2,000 8,089E-03 0,04630064 ! striated muscle cell differentiation GO:0051146 16 15 1,000 8,526E-03 0,04864614 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 8,526E-03 0,048496 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 8,526E-03 0,04834678 ! response to starvation GO:0042594 15 15 1,000 8,526E-03 0,04819848 ! response to ionizing radiation GO:0010212 16 15 1,000 8,526E-03 0,04805108 ! negative regulation of cell activation GO:0050866 15 15 1,000 8,526E-03 0,04790458 ! homophilic cell adhesion GO:0007156 45 45 2,000 8,609E-03 0,04822885 ! regulation of DNA binding GO:0051101 47 45 2,000 8,609E-03 0,0480827 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 8,609E-03 0,04793744 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 8,609E-03 0,04779305 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 8,635E-03 0,04779096 ! tube morphogenesis GO:0035239 47 46 2,000 9,149E-03 0,05048281 ! regulation of peptidase activity GO:0052547 46 46 2,000 9,149E-03 0,05033211 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 9,149E-03 0,05018231 ! positive regulation of ligase activity GO:0051351 47 46 2,000 9,149E-03 0,0500334 ! positive regulation of transferase activity GO:0051347 91 88 3,000 9,35E-03 0,05098415 GO:0033674|positive regulation of kinase activity, ! inner ear morphogenesis GO:0042472 16 16 1,000 9,685E-03 0,05265095 ! positive regulation of mitosis GO:0045840 16 16 1,000 9,685E-03 0,05249609 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 9,685E-03 0,05234214 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 9,685E-03 0,05218909 ! segmentation GO:0035282 17 16 1,000 9,685E-03 0,05203694 ! iron ion homeostasis GO:0055072 16 16 1,000 9,685E-03 0,05188567 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 9,685E-03 0,05173528 ! cellular response to nutrient levels GO:0031669 16 16 1,000 9,685E-03 0,05158575 ! polyol metabolic process GO:0019751 16 16 1,000 9,685E-03 0,05143709 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 9,685E-03 0,05128928 GO:0043507|positive regulation of JUN kinase activity, ! regulation of catabolic process GO:0009894 48 47 2,000 9,708E-03 0,05126354 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 0,01028578 0,054162 ! regulation of cell cycle process GO:0010564 50 48 2,000 0,01028578 0,0540077 ! ossification GO:0001503 50 49 2,000 0,01088371 0,05698486 GO:0060348|bone development, ! response to nutrient GO:0007584 49 49 2,000 0,01088371 0,05682343 ! regulation of ligase activity GO:0051340 50 49 2,000 0,01088371 0,05666291 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 0,01090945 0,05663697 ! myelination GO:0042552 17 17 1,000 0,01090945 0,05647788 ! leukocyte adhesion GO:0007159 17 17 1,000 0,01090945 0,05631968 ! neural crest cell development GO:0014032 19 17 1,000 0,01090945 0,05616236 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 18 17 1,000 0,01090945 0,05600592 GO:0050768|negative regulation of neurogenesis, ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 0,01090945 0,05585034 ! glucose transport GO:0015758 17 17 1,000 0,01090945 0,05569563 ! response to toxin GO:0009636 18 17 1,000 0,01090945 0,05554178 ! liver development GO:0001889 17 17 1,000 0,01090945 0,05538877 ! tissue morphogenesis GO:0048729 94 93 3,000 0,01130493 0,05723899 ! negative regulation of transport GO:0051051 51 50 2,000 0,01150141 0,05807426 ! RNA transport GO:0050658 50 50 2,000 0,01150141 0,05791559 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! regulation of neurogenesis GO:0050767 51 50 2,000 0,01150141 0,05775778 ! anatomical structure homeostasis GO:0060249 51 50 2,000 0,01150141 0,05760083 ! mRNA export from nucleus GO:0006406 18 18 1,000 0,01219894 0,06092859 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 0,01219894 0,06076392 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 0,01219894 0,06060014 ! hexose transport GO:0008645 18 18 1,000 0,01219894 0,06043723 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 0,01219894 0,0602752 ! negative regulation of DNA binding GO:0043392 19 18 1,000 0,01219894 0,06011404 ! telencephalon development GO:0021537 19 18 1,000 0,01219894 0,05995374 ! B cell differentiation GO:0030183 18 18 1,000 0,01219894 0,05979428 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 0,01219894 0,05963568 ! ensheathment of neurons GO:0007272 18 18 1,000 0,01219894 0,05947791 GO:0008366|axon ensheathment, ! RNA localization GO:0006403 52 52 2,000 0,01279662 0,06222737 ! response to light stimulus GO:0009416 53 52 2,000 0,01279662 0,06206361 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 2,000 0,01347432 0,06517892 ! DNA damage checkpoint GO:0000077 19 19 1,000 0,01355175 0,06538186 ! glial cell differentiation GO:0010001 19 19 1,000 0,01355175 0,06521115 ! regulation of pH GO:0006885 19 19 1,000 0,01355175 0,06504133 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01355175 0,06487239 ! regulation of protein stability GO:0031647 19 19 1,000 0,01355175 0,06470433 ! eye morphogenesis GO:0048592 19 19 1,000 0,01355175 0,06453713 ! regulation of cell shape GO:0008360 21 19 1,000 0,01355175 0,0643708 ! placenta development GO:0001890 19 19 1,000 0,01355175 0,06420532 ! hemopoiesis GO:0030097 104 100 3,000 0,01445791 0,06832289 ! in utero embryonic development GO:0001701 55 55 2,000 0,01489033 0,07018641 ! regulation of cell adhesion GO:0030155 56 55 2,000 0,01489033 0,07000736 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 0,0149666 0,07018686 ! negative regulation of binding GO:0051100 21 20 1,000 0,0149666 0,07000873 ! neural tube development GO:0021915 21 20 1,000 0,0149666 0,06983149 ! regulation of nervous system development GO:0051960 57 56 2,000 0,0156288 0,07273707 ! regulation of binding GO:0051098 60 57 2,000 0,01638766 0,07607672 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 0,01644223 0,07613829 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01644223 0,07594746 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01644223 0,07575759 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01644223 0,07556867 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 0,01644223 0,07538069 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 0,01796677 0,08216567 ! regulation of cell development GO:0060284 60 59 2,000 0,01796677 0,08196229 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01797742 0,08180837 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 1,000 0,01797742 0,08160687 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01797742 0,08140636 ! sister chromatid segregation GO:0000819 22 22 1,000 0,01797742 0,08120684 ! odontogenesis GO:0042476 22 22 1,000 0,01797742 0,08100829 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01797742 0,0808107 ! spindle organization GO:0007051 22 22 1,000 0,01797742 0,08061408 ! erythrocyte differentiation GO:0030218 23 22 1,000 0,01797742 0,08041842 ! biopolymer methylation GO:0043414 22 22 1,000 0,01797742 0,0802237 GO:0032259|methylation, ! cytokinesis GO:0000910 23 22 1,000 0,01797742 0,08002992 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,01957094 0,08691384 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01957094 0,08670491 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,01957094 0,08649698 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,01957094 0,08629005 ! regulation of JNK cascade GO:0046328 25 23 1,000 0,01957094 0,08608411 ! cell projection assembly GO:0030031 25 23 1,000 0,01957094 0,08587915 ! mitochondrial transport GO:0006839 24 24 1,000 0,02122158 0,09290114 ! regulation of action potential GO:0001508 24 24 1,000 0,02122158 0,09268099 ! gliogenesis GO:0042063 24 24 1,000 0,02122158 0,09246189 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 0,02122158 0,09224382 ! glucose homeostasis GO:0042593 24 24 1,000 0,02122158 0,09202677 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 0,02122158 0,09181075 ! erythrocyte homeostasis GO:0034101 25 24 1,000 0,02122158 0,09159574 ! maintenance of protein location GO:0045185 25 24 1,000 0,02122158 0,09138173 ! glucan metabolic process GO:0044042 25 24 1,000 0,02122158 0,09116872 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! negative regulation of cellular component organization GO:0051129 65 63 2,000 0,02137169 0,09160005 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,02292817 0,09804319 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,02292817 0,09781623 ! heart morphogenesis GO:0003007 25 25 1,000 0,02292817 0,09759033 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,02292817 0,09736547 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,02292817 0,09714164 ! positive regulation of cytokine production GO:0001819 25 25 1,000 0,02292817 0,09691884 ! positive regulation of binding GO:0051099 27 26 1,000 0,02468952 0,10412537 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,02468952 0,10388765 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,02468952 0,103651 ! response to insulin stimulus GO:0032868 28 26 1,000 0,02468952 0,10341543 ! maintenance of location in cell GO:0051651 27 26 1,000 0,02468952 0,10318093 ! response to radiation GO:0009314 70 68 2,000 0,02609201 0,1087954 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,02650449 0,11026587 ! learning or memory GO:0007611 28 27 1,000 0,02650449 0,11001752 ! activation of caspase activity GO:0006919 27 27 1,000 0,02650449 0,10977029 ! mesenchymal cell development GO:0014031 29 27 1,000 0,02650449 0,10952417 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 1,000 0,02650449 0,10927915 ! tRNA aminoacylation for protein translation GO:0006418 28 28 1,000 0,02837194 0,11671761 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! carbohydrate transport GO:0008643 28 28 1,000 0,02837194 0,11645766 ! histone modification GO:0016570 28 28 1,000 0,02837194 0,11619887 ! developmental growth GO:0048589 28 28 1,000 0,02837194 0,11594122 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,02837194 0,11568471 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,03023934 0,12302673 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,03029075 0,12296444 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,03029075 0,12269419 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,03029075 0,12242512 ! covalent chromatin modification GO:0016569 29 29 1,000 0,03029075 0,12215723 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,03225982 0,12981406 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,03225982 0,12953124 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,03225982 0,12924965 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,03225982 0,12896928 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,03225982 0,12869013 ! establishment of organelle localization GO:0051656 31 30 1,000 0,03225982 0,12841218 ! response to oxidative stress GO:0006979 76 75 2,000 0,03356522 0,13332048 ! membrane fusion GO:0006944 31 31 1,000 0,03427804 0,135859 ! B cell activation GO:0042113 31 31 1,000 0,03427804 0,13556745 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,03427804 0,13527716 ! camera-type eye development GO:0043010 31 31 1,000 0,03427804 0,13498811 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,03588437 0,14101258 ! lipid modification GO:0030258 32 32 1,000 0,03634436 0,14251629 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,03634436 0,14221371 ! nuclear export GO:0051168 32 32 1,000 0,03634436 0,14191241 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,03634436 0,14161239 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,03634436 0,14131363 ! maintenance of location GO:0051235 33 32 1,000 0,03634436 0,14101612 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,03845771 0,14890245 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,03845771 0,14859028 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,03845771 0,14827942 ! neuron projection development GO:0031175 85 80 2,000 0,03951479 0,15203706 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,04061705 0,15595256 ! muscle cell differentiation GO:0042692 35 34 1,000 0,04061705 0,15562834 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,04061705 0,15530546 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,04061705 0,15498391 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,04061705 0,1546637 ! secondary metabolic process GO:0019748 34 34 1,000 0,04061705 0,1543448 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,04061705 0,15402722 ! MAPKKK cascade GO:0000165 82 81 2,000 0,0407651 0,15427122 ! mesoderm development GO:0007498 35 35 1,000 0,04282136 0,16172081 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,04282136 0,1613901 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,04282136 0,16106073 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,04282136 0,1607327 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,0450696 0,16882781 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,0450696 0,16848536 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 0,0450696 0,16814429 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,0450696 0,16780461 ! regulation of lipase activity GO:0060191 36 36 1,000 0,0450696 0,16746629 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,04596517 0,17045031 ! rRNA transcription GO:0009303 5 5 0,000 0,04636741 0,17159664 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04636741 0,17125276 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04636741 0,17091026 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04636741 0,17056912 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! reproductive cellular process GO:0048610 5 5 0,000 0,04636741 0,17022934 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04636741 0,16989091 ! prostate gland development GO:0030850 5 5 0,000 0,04636741 0,16955383 ! metencephalon development GO:0022037 5 5 0,000 0,04636741 0,16921808 ! water transport GO:0006833 5 5 0,000 0,04636741 0,16888365 GO:0042044|fluid transport, ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04636741 0,16855055 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04636741 0,16821876 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04636741 0,16788827 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04636741 0,16755908 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04636741 0,16723117 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04636741 0,16690455 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04636741 0,1665792 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04636741 0,16625511 ! filopodium assembly GO:0046847 7 5 0,000 0,04636741 0,16593229 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04636741 0,16561071 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04636741 0,16529038 ! GTP metabolic process GO:0046039 5 5 0,000 0,04636741 0,16497129 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04636741 0,16465343 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04636741 0,16433679 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04636741 0,16402136 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04636741 0,16370714 ! social behavior GO:0035176 5 5 0,000 0,04636741 0,16339413 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04636741 0,16308231 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,04636741 0,16277167 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,04636741 0,16246222 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04636741 0,16215394 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04636741 0,16184684 ! response to lipid GO:0033993 5 5 0,000 0,04636741 0,16154089 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04636741 0,16123609 ! hippocampus development GO:0021766 6 5 0,000 0,04636741 0,16093245 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04636741 0,16062994 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04636741 0,16032857 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04636741 0,16002833 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04636741 0,15972921 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04636741 0,15943121 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04636741 0,15913432 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04636741 0,15883853 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04636741 0,15854384 ! pH reduction GO:0045851 5 5 0,000 0,04636741 0,15825024 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04636741 0,15795772 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04636741 0,15766629 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04636741 0,15737593 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04636741 0,15708663 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04636741 0,1567984 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04636741 0,15651123 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,04636741 0,1562251 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04636741 0,15594002 ! adrenal gland development GO:0030325 5 5 0,000 0,04636741 0,15565597 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04636741 0,15537296 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04636741 0,15509098 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04636741 0,15481002 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04636741 0,15453007 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04636741 0,15425114 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04636741 0,15397321 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04636741 0,15369628 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04636741 0,15342034 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04636741 0,15314539 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04636741 0,15287143 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04636741 0,15259844 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04636741 0,15232643 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04636741 0,15205539 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04636741 0,15178531 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04636741 0,15151619 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04636741 0,15124802 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04636741 0,15098079 ! response to ATP GO:0033198 5 5 0,000 0,04636741 0,15071451 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04636741 0,15044917 ! regulation of appetite GO:0032098 5 5 0,000 0,04636741 0,15018476 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04636741 0,14992128 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04636741 0,14965872 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04636741 0,14939708 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04636741 0,14913635 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04636741 0,14887653 ! receptor clustering GO:0043113 5 5 0,000 0,04636741 0,14861762 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04636741 0,1483596 ! fear response GO:0042596 5 5 0,000 0,04636741 0,14810248 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,04636741 0,14784624 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04636741 0,1475909 ! retinol metabolic process GO:0042572 5 5 0,000 0,04636741 0,14733643 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04636741 0,14708284 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04636741 0,14683012 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04636741 0,14657827 ! parturition GO:0007567 5 5 0,000 0,04636741 0,14632728 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04636741 0,14607714 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04636741 0,14582787 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04636741 0,14557944 ! protein heterooligomerization GO:0051291 5 5 0,000 0,04636741 0,14533185 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04636741 0,14508511 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04636741 0,1448392 ! response to UV-B GO:0010224 5 5 0,000 0,04636741 0,14459413 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04636741 0,14434988 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04636741 0,14410646 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04636741 0,14386385 ! interaction with symbiont GO:0051702 5 5 0,000 0,04636741 0,14362207 ! cellular extravasation GO:0045123 5 5 0,000 0,04636741 0,14338109 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04636741 0,14314092 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04636741 0,14290155 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04636741 0,14266299 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04636741 0,14242521 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04636741 0,14218823 ! response to amine stimulus GO:0014075 5 5 0,000 0,04636741 0,14195204 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04636741 0,14171663 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04636741 0,141482 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04636741 0,14124815 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04636741 0,14101506 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04636741 0,14078275 ! neuron recognition GO:0008038 5 5 0,000 0,04636741 0,1405512 ! decidualization GO:0046697 5 5 0,000 0,04636741 0,14032041 ! hair follicle maturation GO:0048820 5 5 0,000 0,04636741 0,14009038 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04636741 0,13986109 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,04636741 0,13963256 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04636741 0,13940478 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04636741 0,13917773 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04636741 0,13895143 ! postreplication repair GO:0006301 5 5 0,000 0,04636741 0,13872586 ! cellular pigmentation GO:0033059 5 5 0,000 0,04636741 0,13850102 ! histone methylation GO:0016571 5 5 0,000 0,04636741 0,13827691 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04636741 0,13805352 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04636741 0,13783085 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04636741 0,1376089 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04636741 0,13738767 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04636741 0,13716714 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04636741 0,13694732 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04636741 0,13672821 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04636741 0,13650979 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04636741 0,13629207 ! sterol catabolic process GO:0016127 5 5 0,000 0,04636741 0,13607505 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04636741 0,13585871 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04636741 0,13564306 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04636741 0,1354281 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04636741 0,13521381 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04636741 0,1350002 ! zymogen activation GO:0031638 5 5 0,000 0,04636741 0,13478727 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04636741 0,13457501 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04636741 0,13436341 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,04636741 0,13415248 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04636741 0,13394221 ! nucleosome positioning GO:0016584 5 5 0,000 0,04636741 0,1337326 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04636741 0,13352364 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04636741 0,13331533 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04636741 0,13310768 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04636741 0,13290067 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04636741 0,1326943 ! NADPH regeneration GO:0006740 5 5 0,000 0,04636741 0,13248857 GO:0006098|pentose-phosphate shunt, ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04636741 0,13228348 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04636741 0,13207902 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04636741 0,1318752 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04636741 0,131672 ! sarcomere organization GO:0045214 5 5 0,000 0,04636741 0,13146943 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04636741 0,13126748 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04636741 0,13106615 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04636741 0,13086543 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04636741 0,13066533 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,04636741 0,13046585 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04636741 0,13026696 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,04636741 0,13006869 ! spleen development GO:0048536 5 5 0,000 0,04636741 0,12987102 ! male genitalia development GO:0030539 5 5 0,000 0,04636741 0,12967394 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04636741 0,12947747 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04636741 0,12928159 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04636741 0,1290863 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04636741 0,1288916 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04636741 0,12869748 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04636741 0,12850395 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04636741 0,128311 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04636741 0,12811863 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04636741 0,12792684 ! ATP catabolic process GO:0006200 5 5 0,000 0,04636741 0,12773562 ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04636741 0,12754497 ! blastocyst formation GO:0001825 5 5 0,000 0,04636741 0,12735489 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04636741 0,12716537 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04636741 0,12697642 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04636741 0,12678803 ! activation of innate immune response GO:0002218 5 5 0,000 0,04636741 0,12660019 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,04636741 0,12641291 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04636741 0,12622619 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04636741 0,12604001 ! muscle adaptation GO:0043500 5 5 0,000 0,04636741 0,12585439 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04636741 0,12566931 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04636741 0,12548477 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04636741 0,12530078 ! defense response to fungus GO:0050832 5 5 0,000 0,04636741 0,12511732 ! lysogeny GO:0030069 5 5 0,000 0,04636741 0,1249344 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04636741 0,12475201 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,04636741 0,12457016 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04636741 0,12438883 ! response to nicotine GO:0035094 5 5 0,000 0,04636741 0,12420804 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04636741 0,12402776 ! mitochondrion localization GO:0051646 5 5 0,000 0,04636741 0,12384801 ! nucleus localization GO:0051647 5 5 0,000 0,04636741 0,12366878 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04636741 0,12349007 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,0473608 0,12595377 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,0473608 0,12577228 ! eye development GO:0001654 37 37 1,000 0,0473608 0,12559131 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,0473608 0,12541086 ! adaptive immune response GO:0002250 37 37 1,000 0,0473608 0,12523093 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! chromosome segregation GO:0007059 38 38 1,000 0,04969397 0,13121201 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,04969397 0,13102429 ! RNA elongation GO:0006354 38 38 1,000 0,04969397 0,13083711 ! axon guidance GO:0007411 39 38 1,000 0,04969397 0,13065047 ! intracellular protein transmembrane transport GO:0065002 39 39 1,000 0,05206812 0,13669737 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,05206812 0,13650292 ! activation of MAPK activity GO:0000187 39 39 1,000 0,05206812 0,13630902 ! response to unfolded protein GO:0006986 39 39 1,000 0,05206812 0,13611568 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,05206812 0,13592288 ! limb development GO:0060173 39 39 1,000 0,05206812 0,13573063 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,05448232 0,14182333 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,05448232 0,14162329 ! organelle localization GO:0051640 41 40 1,000 0,05448232 0,14142382 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,05538357 0,14356106 ! axon extension GO:0048675 7 6 0,000 0,05538357 0,14335943 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,05538357 0,14315837 ! tRNA modification GO:0006400 6 6 0,000 0,05538357 0,14295787 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,05538357 0,14275793 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,05538357 0,14255854 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,05538357 0,14235972 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,05538357 0,14216144 ! virus-host interaction GO:0019048 6 6 0,000 0,05538357 0,14196372 ! regulation of S phase GO:0033261 6 6 0,000 0,05538357 0,14176655 ! myotube differentiation GO:0014902 6 6 0,000 0,05538357 0,14156993 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,05538357 0,14137385 ! bone remodeling GO:0046849 6 6 0,000 0,05538357 0,14117831 ! N-glycan processing GO:0006491 6 6 0,000 0,05538357 0,14098331 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,05538357 0,14078885 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,05538357 0,14059493 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,05538357 0,14040154 ! RNA methylation GO:0001510 6 6 0,000 0,05538357 0,14020868 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,05538357 0,14001635 ! succinate metabolic process GO:0006105 7 6 0,000 0,05538357 0,13982454 ! artery development GO:0060840 6 6 0,000 0,05538357 0,13963327 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,05538357 0,13944251 ! bile acid metabolic process GO:0008206 6 6 0,000 0,05538357 0,13925227 ! androgen metabolic process GO:0008209 6 6 0,000 0,05538357 0,13906256 ! estrogen metabolic process GO:0008210 6 6 0,000 0,05538357 0,13887336 ! limbic system development GO:0021761 7 6 0,000 0,05538357 0,13868467 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,05538357 0,13849649 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,05538357 0,13830883 ! pathogenesis GO:0009405 6 6 0,000 0,05538357 0,13812167 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,05538357 0,13793502 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,05538357 0,13774888 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,05538357 0,13756323 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,05538357 0,13737808 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,05538357 0,13719344 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,05538357 0,13700928 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,05538357 0,13682563 ! arginine metabolic process GO:0006525 6 6 0,000 0,05538357 0,13664246 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,05538357 0,13645978 ! glutamate catabolic process GO:0006538 7 6 0,000 0,05538357 0,13627759 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,05538357 0,13609589 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,05538357 0,13591467 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,05538357 0,13573393 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,05538357 0,13555367 ! V(D)J recombination GO:0033151 6 6 0,000 0,05538357 0,13537389 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,05538357 0,13519459 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,05538357 0,13501576 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,05538357 0,13483741 ! regulation of heart rate GO:0002027 6 6 0,000 0,05538357 0,13465952 ! lipid digestion GO:0044241 6 6 0,000 0,05538357 0,1344821 ! asymmetric protein localization GO:0008105 6 6 0,000 0,05538357 0,13430515 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,05538357 0,13412867 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,05538357 0,13395265 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,05538357 0,13377709 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,05538357 0,13360199 ! ruffle organization GO:0031529 6 6 0,000 0,05538357 0,13342734 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,05538357 0,13325316 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,05538357 0,13307942 ! neutral amino acid transport GO:0015804 6 6 0,000 0,05538357 0,13290614 ! L-amino acid transport GO:0015807 6 6 0,000 0,05538357 0,13273331 ! bone mineralization GO:0030282 6 6 0,000 0,05538357 0,13256093 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,05538357 0,132389 ! negative regulation of ossification GO:0030279 6 6 0,000 0,05538357 0,13221751 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,05538357 0,13204646 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,05538357 0,13187586 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,05538357 0,1317057 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,05538357 0,13153598 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,05538357 0,13136669 ! regulation of organ growth GO:0046620 6 6 0,000 0,05538357 0,13119784 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,05538357 0,13102942 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,05538357 0,13086143 ! response to dsRNA GO:0043331 6 6 0,000 0,05538357 0,13069388 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,05538357 0,13052675 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,05538357 0,13036005 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,05538357 0,13019377 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,05538357 0,13002792 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,05538357 0,12986249 ! multicellular organismal aging GO:0010259 6 6 0,000 0,05538357 0,12969748 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,05538357 0,12953289 ! erythrocyte development GO:0048821 6 6 0,000 0,05538357 0,12936872 ! renal water homeostasis GO:0003091 6 6 0,000 0,05538357 0,12920496 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,05538357 0,12904161 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,05538357 0,12887868 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,05538357 0,12871616 ! ribosome assembly GO:0042255 6 6 0,000 0,05538357 0,12855405 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,05538357 0,12839235 ! diencephalon development GO:0021536 6 6 0,000 0,05538357 0,12823105 ! fucose catabolic process GO:0019317 6 6 0,000 0,05538357 0,12807016 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,05538357 0,12790967 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,05538357 0,12774958 ! regulation of lipid transport GO:0032368 6 6 0,000 0,05538357 0,1275899 ! regulation of cell division GO:0051302 6 6 0,000 0,05538357 0,12743061 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,05538357 0,12727172 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,05538357 0,12711322 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,05538357 0,12695512 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,05538357 0,12679741 ! neuroblast proliferation GO:0007405 6 6 0,000 0,05538357 0,1266401 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,05538357 0,12648317 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,05538357 0,12632663 ! regulation of glucose transport GO:0010827 6 6 0,000 0,05538357 0,12617048 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,05538357 0,12601471 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,05538357 0,12585933 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,05538357 0,12570433 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,05538357 0,12554971 ! lymph node development GO:0048535 6 6 0,000 0,05538357 0,12539548 ! organic cation transport GO:0015695 6 6 0,000 0,05538357 0,12524162 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,05538357 0,12508813 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,05538357 0,12493503 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,05538357 0,12478229 ! sperm-egg recognition GO:0035036 7 6 0,000 0,05538357 0,12462994 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,05538357 0,12447795 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,05538357 0,12432633 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,05538357 0,12417508 ! alditol metabolic process GO:0019400 6 6 0,000 0,05538357 0,1240242 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,05538357 0,12387369 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,05538357 0,12372354 ! maternal placenta development GO:0001893 6 6 0,000 0,05538357 0,12357375 ! regulation of embryonic development GO:0045995 6 6 0,000 0,05538357 0,12342433 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,05538357 0,12327526 ! protein ubiquitination GO:0016567 43 42 1,000 0,05942707 0,13211591 ! response to protein stimulus GO:0051789 42 42 1,000 0,05942707 0,13195674 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,05942707 0,13179795 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,05942707 0,13163954 ! mitochondrion organization GO:0007005 44 43 1,000 0,06195579 0,13707624 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,06195579 0,13691188 ! respiratory burst GO:0045730 7 7 0,000 0,06431579 0,14195688 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,06431579 0,14178708 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,06431579 0,14161768 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,06431579 0,14144868 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,06431579 0,14128009 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,06431579 0,1411119 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,06431579 0,14094411 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,06431579 0,14077672 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,06431579 0,14060972 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,06431579 0,14044312 ! gene silencing by RNA GO:0031047 7 7 0,000 0,06431579 0,14027692 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,06431579 0,14011111 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,06431579 0,13994568 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,06431579 0,13978065 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,06431579 0,13961601 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,06431579 0,13945176 ! visual behavior GO:0007632 7 7 0,000 0,06431579 0,13928789 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,06431579 0,13912441 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,06431579 0,13896131 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,06431579 0,13879859 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,06431579 0,13863625 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,06431579 0,13847429 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,06431579 0,13831271 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,06431579 0,13815151 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,06431579 0,13799068 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,06431579 0,13783023 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,06431579 0,13767015 ! protein targeting to ER GO:0045047 8 7 0,000 0,06431579 0,13751044 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,06431579 0,13735109 ! endoderm development GO:0007492 7 7 0,000 0,06431579 0,13719212 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,06431579 0,13703352 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,06431579 0,13687528 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,06431579 0,13671741 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,06431579 0,1365599 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,06431579 0,13640276 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,06431579 0,13624597 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,06431579 0,13608955 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,06431579 0,13593348 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,06431579 0,13577777 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,06431579 0,13562242 ! UV protection GO:0009650 7 7 0,000 0,06431579 0,13546742 ! DNA integration GO:0015074 7 7 0,000 0,06431579 0,13531278 ! myofibril assembly GO:0030239 7 7 0,000 0,06431579 0,13515849 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,06431579 0,13500455 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,06431579 0,13485096 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,06431579 0,13469772 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,06431579 0,13454483 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,06431579 0,13439228 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,06431579 0,13424008 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,06431579 0,13408823 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,06431579 0,13393672 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,06431579 0,13378555 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,06431579 0,13363472 ! axon cargo transport GO:0008088 7 7 0,000 0,06431579 0,13348423 ! eating behavior GO:0042755 7 7 0,000 0,06431579 0,13333408 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,06431579 0,13318426 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,06431579 0,13303479 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,06431579 0,13288564 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,06431579 0,13273684 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,06431579 0,13258836 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,06431579 0,13244022 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,06431579 0,13229241 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,06431579 0,13214492 ! intracellular lipid transport GO:0032365 7 7 0,000 0,06431579 0,13199777 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,06431579 0,13185094 ! platelet activation GO:0030168 8 7 0,000 0,06431579 0,13170444 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,06431579 0,13155826 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,06431579 0,13141241 ! natural killer cell activation GO:0030101 7 7 0,000 0,06431579 0,13126688 ! NADP metabolic process GO:0006739 7 7 0,000 0,06431579 0,13112168 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,06431579 0,13097679 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,06431579 0,13083222 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,06431579 0,13068798 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,06431579 0,13054405 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,06431579 0,13040043 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,06431579 0,13025714 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,06431579 0,13011415 ! cell-cell recognition GO:0009988 8 7 0,000 0,06431579 0,12997149 ! hormone catabolic process GO:0042447 7 7 0,000 0,06431579 0,12982913 ! dopamine metabolic process GO:0042417 7 7 0,000 0,06431579 0,12968708 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,06431579 0,12954535 ! oxygen transport GO:0015671 7 7 0,000 0,06431579 0,12940392 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,06431579 0,12926281 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,06431579 0,129122 ! regulation of axon extension GO:0030516 7 7 0,000 0,06431579 0,1289815 ! cell killing GO:0001906 7 7 0,000 0,06431579 0,1288413 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,06431579 0,12870141 ! adult feeding behavior GO:0008343 7 7 0,000 0,06431579 0,12856182 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,06431579 0,12842253 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,06431579 0,12828354 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,06431579 0,12814486 ! response to cold GO:0009409 7 7 0,000 0,06431579 0,12800647 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,06452085 0,12827608 ! blood circulation GO:0008015 99 98 2,000 0,06499767 0,12908481 GO:0003013|circulatory system process, ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,06712138 0,13315899 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,06975649 0,13823787 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,06975649 0,13808939 ! regulation of membrane potential GO:0042391 46 46 1,000 0,06975649 0,13794122 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,07316483 0,14452603 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,07316483 0,14437129 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,07316483 0,14421688 ! positive regulation of translation GO:0045727 8 8 0,000 0,07316483 0,1440628 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,07316483 0,14390905 ! superoxide anion generation GO:0042554 8 8 0,000 0,07316483 0,14375563 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,07316483 0,14360254 ! cGMP metabolic process GO:0046068 8 8 0,000 0,07316483 0,14344977 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 8 8 0,000 0,07316483 0,14329732 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,07316483 0,1431452 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,07316483 0,14299341 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,07316483 0,14284193 ! zinc ion transport GO:0006829 8 8 0,000 0,07316483 0,14269077 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,07316483 0,14253994 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,07316483 0,14238942 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,07316483 0,14223922 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,07316483 0,14208934 ! lipid localization GO:0010876 8 8 0,000 0,07316483 0,14193977 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,07316483 0,14179052 ! response to cAMP GO:0051591 8 8 0,000 0,07316483 0,14164158 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,07316483 0,14149295 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,07316483 0,14134463 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,07316483 0,14119663 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,07316483 0,14104893 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,07316483 0,14090155 ! sensory perception of taste GO:0050909 8 8 0,000 0,07316483 0,14075447 ! organelle fusion GO:0048284 8 8 0,000 0,07316483 0,1406077 ! pancreas development GO:0031016 8 8 0,000 0,07316483 0,14046123 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,07316483 0,14031507 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,07316483 0,14016921 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,07316483 0,14002366 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,07316483 0,1398784 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,07316483 0,13973345 ! sperm motility GO:0030317 8 8 0,000 0,07316483 0,1395888 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,07316483 0,13944445 ! glycine metabolic process GO:0006544 8 8 0,000 0,07316483 0,13930039 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,07316483 0,13915664 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,07316483 0,13901318 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,07316483 0,13887001 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,07316483 0,13872714 ! Golgi organization GO:0007030 8 8 0,000 0,07316483 0,13858456 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,07316483 0,13844228 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,07316483 0,13830029 ! fructose metabolic process GO:0006000 8 8 0,000 0,07316483 0,13815859 ! mannose metabolic process GO:0006013 9 8 0,000 0,07316483 0,13801718 ! NAD metabolic process GO:0019674 8 8 0,000 0,07316483 0,13787605 ! sex determination GO:0007530 8 8 0,000 0,07316483 0,13773522 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,07316483 0,13759468 ! response to fungus GO:0009620 8 8 0,000 0,07316483 0,13745442 ! stem cell differentiation GO:0048863 8 8 0,000 0,07316483 0,13731444 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,07316483 0,13717475 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,07316483 0,13703535 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,07316483 0,13689622 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,07316483 0,13675738 ! regulation of vasodilation GO:0042312 8 8 0,000 0,07316483 0,13661883 ! vasoconstriction GO:0042310 8 8 0,000 0,07316483 0,13648055 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,07316483 0,13634255 ! muscle cell development GO:0055001 8 8 0,000 0,07316483 0,13620483 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,07316483 0,13606739 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,07316483 0,13593022 ! sensory perception of pain GO:0019233 8 8 0,000 0,07316483 0,13579333 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,07316483 0,13565672 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,07316483 0,13552038 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,07316483 0,13538432 ! chromatin silencing GO:0006342 8 8 0,000 0,07316483 0,13524853 ! tissue regeneration GO:0042246 8 8 0,000 0,07316483 0,13511301 ! salivary gland development GO:0007431 8 8 0,000 0,07316483 0,13497776 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,07316483 0,13484278 ! T cell homeostasis GO:0043029 8 8 0,000 0,07316483 0,13470807 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,07316483 0,13457363 ! water homeostasis GO:0030104 8 8 0,000 0,07316483 0,13443946 ! cofactor transport GO:0051181 8 8 0,000 0,07316483 0,13430556 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,07316483 0,13417192 ! acid secretion GO:0046717 8 8 0,000 0,07316483 0,13403855 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,07316483 0,13390544 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,07316483 0,1337726 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,07316483 0,13364002 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,07316483 0,1335077 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,07316483 0,13337565 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,07316483 0,13324386 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,07316483 0,13311232 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,07316483 0,13298105 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,07316483 0,13285003 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,07316483 0,13271927 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,07316483 0,13258877 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,07316483 0,13245853 ! peptide hormone secretion GO:0030072 8 8 0,000 0,07316483 0,13232854 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,07316483 0,13219881 ! actin filament polymerization GO:0030041 9 8 0,000 0,07316483 0,13206933 ! peptide hormone processing GO:0016486 8 8 0,000 0,07316483 0,1319401 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,07316483 0,13181113 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,07316483 0,1316824 ! actin filament organization GO:0007015 50 48 1,000 0,07512706 0,13508211 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,07512706 0,13495046 ! DNA recombination GO:0006310 48 48 1,000 0,07512706 0,13481905 ! leukocyte differentiation GO:0002521 50 49 1,000 0,07786082 0,13958899 ! T cell activation GO:0042110 51 50 1,000 0,08062579 0,14440557 ! transcription initiation GO:0006352 50 50 1,000 0,08062579 0,14426537 ! lactation GO:0007595 10 9 0,000 0,08193146 0,14645944 ! embryonic pattern specification GO:0009880 10 9 0,000 0,08193146 0,14631752 ! positive regulation of cell size GO:0045793 9 9 0,000 0,08193146 0,14617588 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,08193146 0,14603451 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,08193146 0,14589341 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,08193146 0,14575259 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,08193146 0,14561204 ! viral genome replication GO:0019079 9 9 0,000 0,08193146 0,14547176 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,08193146 0,14533174 ! copper ion transport GO:0006825 9 9 0,000 0,08193146 0,145192 ! lipid phosphorylation GO:0046834 9 9 0,000 0,08193146 0,14505253 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,08193146 0,14491332 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,08193146 0,14477438 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,08193146 0,14463571 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,08193146 0,1444973 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,08193146 0,14435916 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,08193146 0,14422128 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,08193146 0,14408367 ! phospholipid efflux GO:0033700 9 9 0,000 0,08193146 0,14394631 ! response to alkaloid GO:0043279 10 9 0,000 0,08193146 0,14380922 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,08193146 0,14367239 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,08193146 0,14353582 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,08193146 0,14339951 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,08193146 0,14326346 ! response to ethanol GO:0045471 9 9 0,000 0,08193146 0,14312766 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,08193146 0,14299212 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,08193146 0,14285684 ! methionine metabolic process GO:0006555 9 9 0,000 0,08193146 0,14272182 ! glutamine metabolic process GO:0006541 9 9 0,000 0,08193146 0,14258705 ! cerebral cortex development GO:0021987 9 9 0,000 0,08193146 0,14245253 ! response to osmotic stress GO:0006970 9 9 0,000 0,08193146 0,14231827 ! pigmentation during development GO:0048066 9 9 0,000 0,08193146 0,14218426 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,08193146 0,1420505 ! central nervous system neuron development GO:0021954 10 9 0,000 0,08193146 0,14191699 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,08193146 0,14178374 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,08193146 0,14165073 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,08193146 0,14151798 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,08193146 0,14138547 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,08193146 0,14125321 ! L-glutamate transport GO:0015813 9 9 0,000 0,08193146 0,1411212 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,08193146 0,14098943 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,08193146 0,14085791 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,08193146 0,14072664 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,08193146 0,14059561 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,08193146 0,14046482 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,08193146 0,14033428 ! DNA replication initiation GO:0006270 9 9 0,000 0,08193146 0,14020398 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,08193146 0,14007392 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,08193146 0,1399441 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,08193146 0,13981452 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,08193146 0,13968518 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,08193146 0,13955608 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,08193146 0,13942722 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,08193146 0,1392986 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,08193146 0,13917021 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,08193146 0,13904206 ! collagen catabolic process GO:0030574 9 9 0,000 0,08193146 0,13891415 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,08193146 0,13878647 ! purine base metabolic process GO:0006144 9 9 0,000 0,08193146 0,13865903 ! gas transport GO:0015669 9 9 0,000 0,08193146 0,13853182 ! cholesterol efflux GO:0033344 9 9 0,000 0,08193146 0,13840484 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,08193146 0,1382781 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,08193146 0,13815158 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,08193146 0,1380253 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,08193146 0,13789925 ! defense response to virus GO:0051607 9 9 0,000 0,08193146 0,13777343 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,08193146 0,13764784 ! actin filament-based movement GO:0030048 9 9 0,000 0,08193146 0,13752248 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,08193146 0,13739734 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,08342117 0,13976838 ! tRNA metabolic process GO:0006399 53 53 1,000 0,08909995 0,14914733 ! regulation of T cell activation GO:0050863 53 53 1,000 0,08909995 0,14901199 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,09061643 0,15141078 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,09061643 0,15127363 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,09061643 0,15113673 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,09061643 0,15100008 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,09061643 0,15086368 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,09061643 0,15072752 ! neuron maturation GO:0042551 10 10 0,000 0,09061643 0,1505916 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,09061643 0,15045594 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,09061643 0,15032051 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,09061643 0,15018533 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,09061643 0,15005039 ! hormone secretion GO:0046879 10 10 0,000 0,09061643 0,1499157 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,09061643 0,14978125 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,09061643 0,14964703 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! cAMP metabolic process GO:0046058 10 10 0,000 0,09061643 0,14951306 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,09061643 0,14937933 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,09061643 0,14924583 ! glial cell development GO:0021782 10 10 0,000 0,09061643 0,14911258 ! phototransduction GO:0007602 11 10 0,000 0,09061643 0,14897956 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,09061643 0,14884678 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,09061643 0,14871424 ! fat cell differentiation GO:0045444 10 10 0,000 0,09061643 0,14858193 ! myoblast differentiation GO:0045445 10 10 0,000 0,09061643 0,14844986 ! centrosome cycle GO:0007098 10 10 0,000 0,09061643 0,14831802 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,09061643 0,14818641 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,09061643 0,14805504 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,09061643 0,1479239 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,09061643 0,147793 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,09061643 0,14766232 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,09061643 0,14753188 ! protein polyubiquitination GO:0000209 10 10 0,000 0,09061643 0,14740167 ! glutamate metabolic process GO:0006536 11 10 0,000 0,09061643 0,14727168 ! plasma membrane organization GO:0007009 10 10 0,000 0,09061643 0,14714193 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,09061643 0,1470124 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,09061643 0,1468831 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,09061643 0,14675403 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,09061643 0,14662519 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,09061643 0,14649657 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,09061643 0,14636818 ! exocrine system development GO:0035272 10 10 0,000 0,09061643 0,14624001 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,09061643 0,14611206 ! embryo implantation GO:0007566 11 10 0,000 0,09061643 0,14598434 ! regulation of protein binding GO:0043393 11 10 0,000 0,09061643 0,14585685 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,09061643 0,14572957 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,09061643 0,14560252 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,09061643 0,14547569 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,09061643 0,14534908 ! protein export from nucleus GO:0006611 10 10 0,000 0,09061643 0,14522269 ! negative regulation of immune response GO:0050777 10 10 0,000 0,09061643 0,14509651 ! cytolysis GO:0019835 10 10 0,000 0,09061643 0,14497056 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,09061643 0,14484483 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,09061643 0,14471931 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,09061643 0,14459402 ! histone deacetylation GO:0016575 10 10 0,000 0,09061643 0,14446893 ! mRNA splice site selection GO:0006376 11 10 0,000 0,09061643 0,14434407 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,09061643 0,14421942 ! gland morphogenesis GO:0022612 10 10 0,000 0,09061643 0,14409499 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,09061643 0,14397077 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,09061643 0,14384676 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,09061643 0,14372297 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,09061643 0,14359939 ! regulation of epidermis development GO:0045682 10 10 0,000 0,09061643 0,14347602 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,09061643 0,14335287 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,09061643 0,14322992 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,09061643 0,14310719 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,09061643 0,14298466 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,09061643 0,14286235 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,09061643 0,14274025 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,09061643 0,14261835 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,09061643 0,14249666 ! protein stabilization GO:0050821 10 10 0,000 0,09061643 0,14237518 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,09198179 0,1443973 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,0948909 0,14883738 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,0948909 0,14871082 ! protein secretion GO:0009306 11 11 0,000 0,0992205 0,15536396 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,0992205 0,15523207 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,0992205 0,15510041 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,0992205 0,15496897 ! negative regulation of defense response GO:0031348 11 11 0,000 0,0992205 0,15483775 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,0992205 0,15470675 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,0992205 0,15457598 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,0992205 0,15444542 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,0992205 0,15431509 ! skin development GO:0043588 11 11 0,000 0,0992205 0,15418498 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,0992205 0,15405508 ! signal complex assembly GO:0007172 11 11 0,000 0,0992205 0,15392541 ! microtubule-based transport GO:0010970 11 11 0,000 0,0992205 0,15379595 ! peroxisomal transport GO:0043574 11 11 0,000 0,0992205 0,15366671 ! protein amino acid methylation GO:0006479 11 11 0,000 0,0992205 0,15353768 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,0992205 0,15340888 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,0992205 0,15328029 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,0992205 0,15315191 ! T cell proliferation GO:0042098 11 11 0,000 0,0992205 0,15302375 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,0992205 0,1528958 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,0992205 0,15276807 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,0992205 0,15264055 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,0992205 0,15251325 ! smooth muscle contraction GO:0006939 11 11 0,000 0,0992205 0,15238615 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,0992205 0,15225927 ! digestive system process GO:0022600 11 11 0,000 0,0992205 0,1521326 ! mitotic spindle organization GO:0007052 11 11 0,000 0,0992205 0,15200614 ! fucose metabolic process GO:0006004 11 11 0,000 0,0992205 0,15187989 ! membrane budding GO:0006900 11 11 0,000 0,0992205 0,15175384 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,0992205 0,15162801 ! monoamine transport GO:0015844 11 11 0,000 0,0992205 0,15150239 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,0992205 0,15137697 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,0992205 0,15125176 ! body fluid secretion GO:0007589 11 11 0,000 0,0992205 0,15112676 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,0992205 0,15100197 ! intermediate filament-based process GO:0045103 11 11 0,000 0,0992205 0,15087738 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,0992205 0,15075299 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,0992205 0,15062882 ! membrane depolarization GO:0051899 11 11 0,000 0,0992205 0,15050484 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,0992205 0,15038107 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,0992205 0,1502575 ! oogenesis GO:0048477 11 11 0,000 0,0992205 0,15013414 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,0992205 0,15001098 ! vitamin transport GO:0051180 11 11 0,000 0,0992205 0,14988802 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,0992205 0,14976526 ! steroid catabolic process GO:0006706 11 11 0,000 0,0992205 0,1496427 ! endocrine process GO:0050886 11 11 0,000 0,0992205 0,14952034 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,0992205 0,14939819 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,0992205 0,14927623 ! translational initiation GO:0006413 12 12 0,000 0,1077444 0,16196813 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,1077444 0,16183613 ! initiation of viral infection GO:0019059 12 12 0,000 0,1077444 0,16170434 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,1077444 0,16157277 ! iron ion transport GO:0006826 13 12 0,000 0,1077444 0,16144141 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,1077444 0,16131026 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,1077444 0,16117933 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,1077444 0,1610486 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,1077444 0,16091809 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,1077444 0,1607878 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,1077444 0,16065771 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,1077444 0,16052783 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,1077444 0,16039817 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,1077444 0,16026871 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,1077444 0,16013946 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,1077444 0,16001042 ! actomyosin structure organization GO:0031032 12 12 0,000 0,1077444 0,15988159 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,1077444 0,15975296 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,1077444 0,15962454 ! retinoid metabolic process GO:0001523 12 12 0,000 0,1077444 0,15949633 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,1077444 0,15936832 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,1077444 0,15924052 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,1077444 0,15911292 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,1077444 0,15898553 ! acute-phase response GO:0006953 12 12 0,000 0,1077444 0,15885834 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,1077444 0,15873136 ! vacuolar transport GO:0007034 12 12 0,000 0,1077444 0,15860458 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,1077444 0,158478 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,1077444 0,15835162 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,1077444 0,15822544 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,1077444 0,15809947 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,1077444 0,15797369 ! male gonad development GO:0008584 12 12 0,000 0,1077444 0,15784812 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,1077444 0,15772274 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,1077444 0,15759756 ! renal system process GO:0003014 12 12 0,000 0,1077444 0,15747258 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,1077444 0,1573478 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,1077444 0,15722322 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,1077444 0,15709884 ! pallium development GO:0021543 13 12 0,000 0,1077444 0,15697465 ! cell fate determination GO:0001709 12 12 0,000 0,1077444 0,15685065 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,1077444 0,15672686 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,1077444 0,15660326 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,1077444 0,15647985 ! detection of light stimulus GO:0009583 13 12 0,000 0,1077444 0,15635664 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,1077444 0,15623362 ! hormone transport GO:0009914 12 12 0,000 0,1077444 0,15611079 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,1077444 0,15598816 ! heme biosynthetic process GO:0006783 12 12 0,000 0,1077444 0,15586572 ! spermatid differentiation GO:0048515 13 12 0,000 0,1077444 0,15574347 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,1077444 0,15562142 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,1077444 0,15549955 ! neural tube closure GO:0001843 13 12 0,000 0,1077444 0,15537788 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,1077444 0,15525639 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,1077444 0,1551351 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,11287696 0,16239831 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! axonogenesis GO:0007409 66 62 1,000 0,11595654 0,16669884 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,11595654 0,16656891 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,11595654 0,16643918 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,11618887 0,16664287 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,11618887 0,16651329 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,11618887 0,16638391 ! phenol metabolic process GO:0018958 13 13 0,000 0,11618887 0,16625472 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,11618887 0,16612575 ! gluconeogenesis GO:0006094 13 13 0,000 0,11618887 0,16599697 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,11618887 0,16586839 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,11618887 0,16574 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,11618887 0,16561182 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,11618887 0,16548384 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,11618887 0,16535605 ! regeneration GO:0031099 13 13 0,000 0,11618887 0,16522846 ! keratinization GO:0031424 13 13 0,000 0,11618887 0,16510107 ! post-embryonic development GO:0009791 14 13 0,000 0,11618887 0,16497387 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,11618887 0,16484687 ! patterning of blood vessels GO:0001569 13 13 0,000 0,11618887 0,16472007 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,11618887 0,16459346 ! regulation of innate immune response GO:0045088 13 13 0,000 0,11618887 0,16446704 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,11618887 0,16434082 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,11618887 0,16421479 ! autophagy GO:0006914 13 13 0,000 0,11618887 0,16408895 ! receptor metabolic process GO:0043112 14 13 0,000 0,11618887 0,16396331 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,11618887 0,16383786 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,11618887 0,1637126 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,11618887 0,16358754 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,11618887 0,16346266 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,11618887 0,16333798 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,11618887 0,16321348 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,11618887 0,16308917 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,11618887 0,16296506 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,11618887 0,16284113 ! vasodilation GO:0042311 14 13 0,000 0,11618887 0,16271739 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,11618887 0,16259384 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,11618887 0,16247047 GO:0006664|glycolipid metabolic process, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,11618887 0,1623473 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,11618887 0,16222431 ! immunoglobulin production GO:0002377 13 13 0,000 0,11618887 0,1621015 GO:0002440|production of molecular mediator of immune response, ! cell-cell junction organization GO:0045216 13 13 0,000 0,11618887 0,16197888 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,11618887 0,16185645 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,11618887 0,1617342 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,11618887 0,16161214 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,11618887 0,16149026 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,11618887 0,16136856 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,11618887 0,16124705 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,11618887 0,16112572 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,11618887 0,16100458 ! blastocyst development GO:0001824 13 13 0,000 0,11618887 0,16088361 ! telomere organization GO:0032200 13 13 0,000 0,11618887 0,16076283 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,11618887 0,16064222 ! regulation of amine transport GO:0051952 13 13 0,000 0,11618887 0,1605218 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,11618887 0,16040156 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,12217972 0,16854583 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,12217972 0,16841977 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,12217972 0,1682939 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,12455464 0,17143704 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,12455464 0,1713091 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,12455464 0,17118135 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,12455464 0,1710538 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,12455464 0,17092643 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,12455464 0,17079925 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,12455464 0,17067226 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,12455464 0,17054546 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,12455464 0,17041885 ! vesicle docking GO:0048278 14 14 0,000 0,12455464 0,17029243 ! superoxide metabolic process GO:0006801 15 14 0,000 0,12455464 0,17016619 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,12455464 0,17004014 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,12455464 0,16991428 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,12455464 0,16978861 ! hair cycle GO:0042633 14 14 0,000 0,12455464 0,16966312 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,12455464 0,16953781 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,12455464 0,16941269 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,12455464 0,16928775 ! lysosome organization GO:0007040 14 14 0,000 0,12455464 0,169163 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,12455464 0,16903843 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,12455464 0,16891405 ! peptide transport GO:0015833 14 14 0,000 0,12455464 0,16878985 ! primary neural tube formation GO:0014020 15 14 0,000 0,12455464 0,16866583 ! peptide cross-linking GO:0018149 14 14 0,000 0,12455464 0,16854199 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,12455464 0,16841834 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,12455464 0,16829486 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,12455464 0,16817157 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,12455464 0,16804846 ! formation of primary germ layer GO:0001704 14 14 0,000 0,12455464 0,16792553 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,12455464 0,16780277 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,12455464 0,1676802 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,12455464 0,16755781 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,12455464 0,16743559 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,12455464 0,16731355 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,12455464 0,16719169 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,12455464 0,16707001 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,12455464 0,16694851 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,12455464 0,16682718 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,12455464 0,16670602 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,125322 0,16761136 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,12848388 0,17171559 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,13166472 0,17583919 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,13284242 0,17728355 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,13284242 0,17715527 ! positive regulation of ossification GO:0045778 15 15 0,000 0,13284242 0,17702718 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,13284242 0,17689927 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,13284242 0,17677154 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,13284242 0,176644 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,13284242 0,17651665 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,13284242 0,17638947 ! ovarian follicle development GO:0001541 15 15 0,000 0,13284242 0,17626248 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,13284242 0,17613567 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,13284242 0,17600905 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,13284242 0,17588261 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,13284242 0,17575634 ! heme metabolic process GO:0042168 15 15 0,000 0,13284242 0,17563026 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,13284242 0,17550436 ! chromosome condensation GO:0030261 15 15 0,000 0,13284242 0,17537864 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,13284242 0,1752531 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,13284242 0,17512774 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,13284242 0,17500256 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,13284242 0,17487756 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,13284242 0,17475274 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,13284242 0,17462809 ! phospholipid transport GO:0015914 15 15 0,000 0,13284242 0,17450363 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,13284242 0,17437934 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,13284242 0,17425522 ! glutathione metabolic process GO:0006749 16 15 0,000 0,13284242 0,17413129 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,13284242 0,17400752 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,13284242 0,17388394 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,13284242 0,17376053 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,13284242 0,1736373 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,13284242 0,17351424 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,13284242 0,17339135 ! regulation of translation GO:0006417 69 69 1,000 0,13808079 0,18010112 ! sensory perception of sound GO:0007605 71 69 1,000 0,13808079 0,17997375 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,13808079 0,17984656 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,14105295 0,18358798 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,14105295 0,18345842 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,14105295 0,18332904 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,14105295 0,18319985 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,14105295 0,18307083 ! learning GO:0007612 16 16 0,000 0,14105295 0,182942 ! circadian rhythm GO:0007623 16 16 0,000 0,14105295 0,18281335 ! vacuole organization GO:0007033 16 16 0,000 0,14105295 0,18268488 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,14105295 0,18255659 ! vesicle targeting GO:0006903 17 16 0,000 0,14105295 0,18242848 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,14105295 0,18230055 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,14105295 0,1821728 ! positive regulation of cell development GO:0010720 16 16 0,000 0,14105295 0,18204523 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,14105295 0,18191783 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,14105295 0,18179062 ! pentose metabolic process GO:0019321 16 16 0,000 0,14105295 0,18166358 ! fatty acid transport GO:0015908 16 16 0,000 0,14105295 0,18153672 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,14105295 0,18141004 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,14105295 0,18128353 ! cofactor catabolic process GO:0051187 16 16 0,000 0,14105295 0,1811572 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,14105295 0,18103105 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,14105295 0,18090507 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,14105295 0,18077926 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,14105295 0,18065364 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,14105295 0,18052818 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,14105295 0,1804029 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,14105295 0,1802778 ! regulation of coagulation GO:0050818 17 16 0,000 0,14105295 0,18015286 ! cell part morphogenesis GO:0032990 75 70 1,000 0,14131479 0,1803623 ! growth GO:0040007 70 70 1,000 0,14131479 0,18023748 ! ribosome biogenesis GO:0042254 71 71 1,000 0,14456532 0,1842558 ! regulation of cell activation GO:0050865 71 71 1,000 0,14456532 0,18412846 ! regulation of cytokine production GO:0001817 72 72 1,000 0,14783177 0,18815881 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,14918692 0,18975258 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,14918692 0,18962171 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,14918692 0,18949103 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,14918692 0,18936053 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,14918692 0,1892302 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,14918692 0,18910006 ! sensory perception of smell GO:0007608 17 17 0,000 0,14918692 0,18897009 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,14918692 0,18884031 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,14918692 0,1887107 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,14918692 0,18858127 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,14918692 0,18845201 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,14918692 0,18832293 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,14918692 0,18819403 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,14918692 0,18806531 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,14918692 0,18793676 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,14918692 0,18780839 ! pigmentation GO:0043473 17 17 0,000 0,14918692 0,18768019 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,14918692 0,18755217 ! adult locomotory behavior GO:0008344 17 17 0,000 0,14918692 0,18742433 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,14918692 0,18729665 ! gene silencing GO:0016458 17 17 0,000 0,14918692 0,18716915 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,15724503 0,19714462 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,15724503 0,1970106 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,15724503 0,19687676 ! membrane docking GO:0022406 18 18 0,000 0,15724503 0,1967431 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,15724503 0,19660963 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,15724503 0,19647633 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,15724503 0,19634322 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,15724503 0,19621029 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,15724503 0,19607753 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,15724503 0,19594496 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,15724503 0,19581256 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,15724503 0,19568035 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,15724503 0,19554831 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,15724503 0,19541645 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,15724503 0,19528477 ! BMP signaling pathway GO:0030509 18 18 0,000 0,15724503 0,19515326 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,15724503 0,19502193 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,15724503 0,19489078 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,15724503 0,19475981 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,15724503 0,19462901 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,1610455 0,19919923 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,16522799 0,20423554 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,16522799 0,20409865 GO:0006956|complement activation, ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,16522799 0,20396195 ! feeding behavior GO:0007631 19 19 0,000 0,16522799 0,20382543 ! peroxisome organization GO:0007031 19 19 0,000 0,16522799 0,20368909 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,16522799 0,20355293 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,16522799 0,20341696 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,16522799 0,20328117 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,16522799 0,20314556 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,16522799 0,20301013 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,16522799 0,20287488 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,16522799 0,20273981 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,16522799 0,20260492 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,16522799 0,20247021 ! response to heat GO:0009408 19 19 0,000 0,16522799 0,20233567 ! vesicle localization GO:0051648 20 19 0,000 0,16522799 0,20220132 ! regulation of muscle development GO:0048634 21 20 0,000 0,17313649 0,21173891 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,17313649 0,2115985 ! organic ether metabolic process GO:0018904 20 20 0,000 0,17313649 0,21145828 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,17313649 0,21131824 ! nucleus organization GO:0006997 20 20 0,000 0,17313649 0,21117839 ! phagocytosis GO:0006909 21 20 0,000 0,17313649 0,21103872 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,17313649 0,21089924 ! protein targeting to membrane GO:0006612 22 20 0,000 0,17313649 0,21075994 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,17313649 0,21062082 ! chromatin remodeling GO:0006338 20 20 0,000 0,17313649 0,21048189 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,17313649 0,21034314 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,17313649 0,21020457 ! lipid oxidation GO:0034440 20 20 0,000 0,17313649 0,21006619 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,17313649 0,20992799 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,17313649 0,20978997 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,17313649 0,20965213 ! RNA modification GO:0009451 20 20 0,000 0,17313649 0,20951447 ! single fertilization GO:0007338 21 20 0,000 0,17313649 0,209377 ! regulation of B cell activation GO:0050864 20 20 0,000 0,17313649 0,2092397 ! lymphocyte activation GO:0046649 82 81 1,000 0,17785446 0,21480063 ! mRNA catabolic process GO:0006402 21 21 0,000 0,1809712 0,21842169 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,1809712 0,21827874 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,1809712 0,21813598 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,1809712 0,21799341 ! Notch signaling pathway GO:0007219 22 21 0,000 0,1809712 0,21785102 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,1809712 0,21770882 ! organic anion transport GO:0015711 21 21 0,000 0,1809712 0,21756681 ! cholesterol transport GO:0030301 21 21 0,000 0,1809712 0,21742498 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,1809712 0,21728333 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,1809712 0,21714187 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,1809712 0,2170006 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,1809712 0,21685951 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,1809712 0,2167186 ! regulation of proteolysis GO:0030162 21 21 0,000 0,1809712 0,21657787 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,1809712 0,21643733 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,18873281 0,22557365 ! regulation of ion transport GO:0043269 22 22 0,000 0,18873281 0,22542746 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,18873281 0,22528145 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,18873281 0,22513564 ! ovulation cycle process GO:0022602 22 22 0,000 0,18873281 0,22499002 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,18873281 0,22484458 ! cell chemotaxis GO:0060326 23 22 0,000 0,18873281 0,22469933 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,18873281 0,22455427 ! male sex differentiation GO:0046661 22 22 0,000 0,18873281 0,2244094 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,18873281 0,22426471 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,18873281 0,22412021 ! detection of external stimulus GO:0009581 23 22 0,000 0,18873281 0,22397589 ! neuron migration GO:0001764 22 22 0,000 0,18873281 0,22383177 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,18873281 0,22368782 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,18873281 0,22354406 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,18873281 0,22340049 ! aerobic respiration GO:0009060 22 22 0,000 0,18873281 0,2232571 ! cytokine production GO:0001816 22 22 0,000 0,18873281 0,2231139 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,18873281 0,22297087 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,19149482 0,22608902 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,19492769 0,2299947 GO:0006644|phospholipid metabolic process, ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,19642198 0,23160954 ! viral infectious cycle GO:0019058 23 23 0,000 0,19642198 0,23146145 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,19642198 0,23131356 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,19642198 0,23116585 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,19642198 0,23101832 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,19642198 0,23087099 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,19642198 0,23072385 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,19642198 0,23057689 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,19642198 0,23043012 ! positive regulation of growth GO:0045927 23 23 0,000 0,19642198 0,23028353 ! female gonad development GO:0008585 23 23 0,000 0,19642198 0,23013714 ! lipid homeostasis GO:0055088 23 23 0,000 0,19642198 0,22999092 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,19642198 0,2298449 ! male gamete generation GO:0048232 90 88 1,000 0,20181751 0,23600867 GO:0007283|spermatogenesis, ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,20403939 0,23845567 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,20403939 0,23830456 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,20403939 0,23815364 ! ovulation cycle GO:0042698 24 24 0,000 0,20403939 0,23800291 ! fertilization GO:0009566 25 24 0,000 0,20403939 0,23785237 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,20403939 0,23770202 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,20527356 0,23898874 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,21158569 0,24618209 ! negative regulation of secretion GO:0051048 26 25 0,000 0,21158569 0,24602677 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,21158569 0,24587165 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,21158569 0,24571672 ! cellular component disassembly GO:0022411 26 25 0,000 0,21158569 0,24556198 ! endosome transport GO:0016197 25 25 0,000 0,21158569 0,24540745 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,21158569 0,2452531 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,21158569 0,24509895 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,21158569 0,24494499 ! excretion GO:0007588 25 25 0,000 0,21158569 0,24479123 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,21158569 0,24463766 ! gastrulation GO:0007369 25 25 0,000 0,21158569 0,24448428 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,21158569 0,2443311 ! regulation of endocytosis GO:0030100 25 25 0,000 0,21158569 0,2441781 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,21220579 0,24474047 ! visual perception GO:0007601 93 92 1,000 0,21568111 0,24859305 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,21568111 0,24843768 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,21568111 0,2482825 ! positive regulation of defense response GO:0031349 26 26 0,000 0,21906154 0,25201649 ! glycolysis GO:0006096 26 26 0,000 0,21906154 0,25185927 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,21906154 0,25170226 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,21906154 0,25154543 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,21906154 0,2513888 ! cellular defense response GO:0006968 26 26 0,000 0,21906154 0,25123237 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,21906154 0,25107613 ! regulation of protein secretion GO:0050708 26 26 0,000 0,21906154 0,25092009 ! germ cell development GO:0007281 27 26 0,000 0,21906154 0,25076423 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,21906154 0,25060858 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,21906154 0,25045311 ! regulation of response to stress GO:0080134 97 94 1,000 0,22264808 0,25439579 ! epidermis development GO:0008544 94 94 1,000 0,22264808 0,25423818 ! chloride transport GO:0006821 27 27 0,000 0,22646758 0,25843947 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,22646758 0,25827955 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,22646758 0,25811982 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,22646758 0,25796029 ! peptide metabolic process GO:0006518 29 27 0,000 0,22646758 0,25780096 ! defense response to bacterium GO:0042742 27 27 0,000 0,22646758 0,25764182 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,22646758 0,25748288 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,22646758 0,25732414 ! cell growth GO:0016049 27 27 0,000 0,22646758 0,25716559 ! neuromuscular process GO:0050905 28 28 0,000 0,23380446 0,2653335 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,23380446 0,26517022 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,23380446 0,26500714 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,23380446 0,26484426 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,23380446 0,26468158 ! endocytosis GO:0006897 99 98 1,000 0,2366362 0,26772284 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,2366362 0,26755859 ! anti-apoptosis GO:0006916 100 99 1,000 0,24014226 0,27135634 ! ectoderm development GO:0007398 99 99 1,000 0,24014226 0,27119006 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,2410728 0,2720742 ! viral reproductive process GO:0022415 29 29 0,000 0,2410728 0,27190769 ! leukocyte migration GO:0050900 30 29 0,000 0,2410728 0,27174139 ! antigen processing and presentation GO:0019882 29 29 0,000 0,2410728 0,27157529 ! tRNA processing GO:0008033 29 29 0,000 0,2410728 0,27140939 ! adult behavior GO:0030534 30 29 0,000 0,2410728 0,2712437 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,2410728 0,2710782 ! response to hormone stimulus GO:0009725 102 100 1,000 0,24365119 0,27381046 ! transition metal ion transport GO:0000041 31 30 0,000 0,24827325 0,27883461 ! RNA catabolic process GO:0006401 30 30 0,000 0,24827325 0,2786648 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,24827325 0,27849519 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,24827325 0,27832579 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,24827325 0,27815659 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,24827325 0,27798761 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,24827325 0,27781882 ! response to temperature stimulus GO:0009266 30 30 0,000 0,24827325 0,27765024 ! regulation of ossification GO:0030278 30 30 0,000 0,24827325 0,27748187 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,24827325 0,2773137 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,24827325 0,27714573 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,24827325 0,27697797 ! vesicle organization GO:0016050 30 30 0,000 0,24827325 0,2768104 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,24827325 0,27664305 ! regulation of translational initiation GO:0006446 31 31 0,000 0,25540642 0,28441936 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,25540642 0,28424761 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,25540642 0,28407606 ! ion transmembrane transport GO:0034220 31 31 0,000 0,25540642 0,28390473 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,25540642 0,2837336 ! digestion GO:0007586 31 31 0,000 0,25540642 0,28356267 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,25540642 0,28339196 ! regulation of heart contraction GO:0008016 31 31 0,000 0,25540642 0,28322144 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,25540642 0,28305113 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,25540642 0,28288103 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,25540642 0,28271113 ! cell redox homeostasis GO:0045454 32 32 0,000 0,26247294 0,29035872 ! glucose catabolic process GO:0006007 32 32 0,000 0,26247294 0,29018454 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,26247294 0,29001057 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,26247294 0,28983681 ! cell maturation GO:0048469 32 32 0,000 0,26247294 0,28966325 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,26247294 0,2894899 ! amino acid transport GO:0006865 33 33 0,000 0,26947342 0,2970332 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,26947342 0,29685565 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,26947342 0,29667832 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,26947342 0,2965012 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,26947342 0,29632429 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,26947342 0,29614759 ! regulation of actin filament length GO:0030832 34 34 0,000 0,27640846 0,30358807 ! response to metal ion GO:0010038 34 34 0,000 0,27640846 0,30340726 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,27640846 0,30322666 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,27640846 0,30304628 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,27640846 0,3028661 ! viral reproduction GO:0016032 34 34 0,000 0,27640846 0,30268615 ! detection of stimulus GO:0051606 36 34 0,000 0,27640846 0,30250641 ! acute inflammatory response GO:0002526 35 35 0,000 0,28327867 0,3098413 ! regulation of cellular component size GO:0032535 35 35 0,000 0,28327867 0,30965752 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,28327867 0,30947397 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,28327867 0,30929063 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,28327867 0,30910751 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,28327867 0,30892461 ! regulation of immune effector process GO:0002697 35 35 0,000 0,28327867 0,30874192 ! hydrogen transport GO:0006818 36 36 0,000 0,29008464 0,31597281 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,29008464 0,31578617 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,29008464 0,31559976 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,29008464 0,31541356 ! female pregnancy GO:0007565 37 36 0,000 0,29008464 0,31522759 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,29008464 0,31504183 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,29008464 0,3148563 ! gonad development GO:0008406 36 36 0,000 0,29008464 0,31467098 ! activation of immune response GO:0002253 36 36 0,000 0,29008464 0,31448588 ! coagulation GO:0050817 39 36 0,000 0,29008464 0,31430099 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,29682697 0,32141722 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,29682697 0,32122848 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,29682697 0,32103997 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,29682697 0,32085167 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,29682697 0,3206636 ! positive regulation of secretion GO:0051047 39 38 0,000 0,30350624 0,32768717 ! neurotransmitter transport GO:0006836 40 38 0,000 0,30350624 0,32749532 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,30350624 0,32730369 ! exocytosis GO:0006887 40 38 0,000 0,30350624 0,32711228 ! hexose catabolic process GO:0019320 38 38 0,000 0,30350624 0,3269211 ! regulation of neurological system process GO:0031644 38 38 0,000 0,30350624 0,32673014 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,31012303 0,33365835 ! hemostasis GO:0007599 42 39 0,000 0,31012303 0,33346368 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,31012303 0,33326924 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,31012303 0,33307503 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,31012303 0,33288104 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,31012303 0,33268728 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,31012303 0,33249375 ! developmental maturation GO:0021700 39 39 0,000 0,31012303 0,33230043 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,31667792 0,33912691 ! DNA catabolic process GO:0006308 41 40 0,000 0,31667792 0,33892997 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,32317148 0,34567907 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,32317148 0,34547856 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,32317148 0,34527828 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,32317148 0,34507824 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,32317148 0,34487842 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,32317148 0,34467884 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,32317148 0,34447949 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,32960427 0,35113334 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,32960427 0,35093049 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,32960427 0,35072787 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,32960427 0,35052549 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,32960427 0,35032334 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! reproductive structure development GO:0048608 43 43 0,000 0,33597685 0,35689069 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,33597685 0,3566851 ! alcohol catabolic process GO:0046164 43 43 0,000 0,33597685 0,35647976 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,33597685 0,35627465 ! humoral immune response GO:0006959 44 44 0,000 0,34228978 0,36276025 ! vitamin metabolic process GO:0006766 44 44 0,000 0,34228978 0,36255177 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,34228978 0,36234352 ! amine biosynthetic process GO:0009309 46 45 0,000 0,34854361 0,36875194 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,34854361 0,36854038 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,34854361 0,36832906 ! protein processing GO:0016485 45 45 0,000 0,34854361 0,36811798 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,35473888 0,3744466 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,35473888 0,37423226 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,36087613 0,38048896 ! regulation of blood pressure GO:0008217 48 47 0,000 0,36087613 0,38027142 ! sex differentiation GO:0007548 47 47 0,000 0,36087613 0,38005412 ! amine transport GO:0015837 47 47 0,000 0,36087613 0,37983707 ! rhythmic process GO:0048511 47 47 0,000 0,36087613 0,37962027 ! calcium ion transport GO:0006816 48 48 0,000 0,3669559 0,38579562 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,37297871 0,39190409 ! divalent metal ion transport GO:0070838 49 49 0,000 0,37297871 0,39168078 ! response to bacterium GO:0009617 50 49 0,000 0,37297871 0,39145773 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,37297871 0,39123493 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,37297871 0,39101238 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,3789451 0,3970414 ! chromatin assembly GO:0031497 50 50 0,000 0,3789451 0,39681581 GO:0006334|nucleosome assembly, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,3789451 0,39659047 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,3789451 0,39636539 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,38485558 0,40231925 ! positive regulation of immune response GO:0050778 51 51 0,000 0,38485558 0,40209117 ! rRNA metabolic process GO:0016072 51 51 0,000 0,38485558 0,40186336 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,38485558 0,4016358 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,38485558 0,40140851 ! protein maturation GO:0051604 51 51 0,000 0,38485558 0,40118146 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,39071066 0,40705469 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,39071066 0,40682472 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,39071066 0,40659501 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,39071066 0,40636555 ! sodium ion transport GO:0006814 53 53 0,000 0,39651087 0,41216556 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,39651087 0,41193322 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,39651087 0,41170115 ! response to virus GO:0009615 54 54 0,000 0,4022567 0,41743193 ! hormone metabolic process GO:0042445 55 54 0,000 0,4022567 0,41719702 ! sulfur metabolic process GO:0006790 55 54 0,000 0,4022567 0,41696237 ! nucleosome organization GO:0034728 55 55 0,000 0,40794866 0,42262472 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,40794866 0,42238729 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,41358725 0,427985 ! reproductive developmental process GO:0003006 56 56 0,000 0,41358725 0,42774483 ! ATP metabolic process GO:0046034 57 57 0,000 0,41917295 0,4332786 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,41917295 0,43303573 ! innate immune response GO:0045087 58 58 0,000 0,42470626 0,43850623 ! carboxylic acid transport GO:0046942 59 59 0,000 0,43018765 0,44391705 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,43018765 0,44366863 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,43018765 0,44342049 ! immune effector process GO:0002252 59 59 0,000 0,43018765 0,44317263 ! potassium ion transport GO:0006813 60 60 0,000 0,43561762 0,44851579 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,43561762 0,44826537 ! protein polymerization GO:0051258 65 60 0,000 0,43561762 0,44801522 ! cellular respiration GO:0045333 62 61 0,000 0,44099663 0,45329436 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,44099663 0,45304169 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,44099663 0,4527893 ! lipid transport GO:0006869 62 62 0,000 0,44632516 0,45800516 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,44632516 0,45775029 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,44632516 0,4574957 ! regulation of secretion GO:0051046 65 63 0,000 0,45160366 0,462649 ! glucose metabolic process GO:0006006 63 63 0,000 0,45160366 0,46239197 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,45160366 0,46213523 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,45160366 0,46187877 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,45683262 0,46696756 ! anion transport GO:0006820 65 65 0,000 0,46201247 0,47200054 ! regulation of hormone levels GO:0010817 66 65 0,000 0,46201247 0,47173905 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,46714368 0,47671417 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,46714368 0,47645036 ! DNA packaging GO:0006323 66 66 0,000 0,46714368 0,47618684 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,46714368 0,4759236 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,47222669 0,48083635 ! muscle contraction GO:0006936 67 67 0,000 0,47222669 0,48057084 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,47222669 0,48030563 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,47726196 0,48515929 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,47726196 0,48489183 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,487191 0,4947069 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,49208566 0,49940191 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,49208566 0,49912706 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,49208566 0,49885251 GO:0006874|cellular calcium ion homeostasis, ! secretion by cell GO:0032940 75 72 0,000 0,4969343 0,50349089 ! muscle system process GO:0003012 72 72 0,000 0,4969343 0,50321424 ! electron transport chain GO:0022900 75 74 0,000 0,50649528 0,51261438 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,50649528 0,51233304 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,51120844 0,51681687 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,51120844 0,51653353 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,5205022 0,52563592 ! microtubule-based movement GO:0007018 82 78 0,000 0,52508362 0,52997213 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,52508362 0,52968205 ! metal ion homeostasis GO:0055065 78 78 0,000 0,52508362 0,52939229 ! regulation of immune response GO:0050776 78 78 0,000 0,52508362 0,52910285 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,53411752 0,5379118 ! lipid catabolic process GO:0016042 82 81 0,000 0,53857081 0,5421005 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,54735202 0,55063852 ! ncRNA processing GO:0034470 83 83 0,000 0,54735202 0,55033812 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,55168071 0,55438798 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,55596864 0,55839248 ! hexose metabolic process GO:0019318 87 86 0,000 0,56021618 0,56235208 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,5685916 0,57044873 ! chemotaxis GO:0006935 90 89 0,000 0,57272021 0,57427821 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,57680991 0,57806453 ! fatty acid metabolic process GO:0006631 93 92 0,000 0,58487404 0,58582764 ! cofactor metabolic process GO:0051186 95 94 0,000 0,59278682 0,5934308 ! regulation of system process GO:0044057 98 98 0,000 0,60816947 0,60849963 ! response to other organism GO:0051707 101 100 0,000 0,61564478 0,61564478