pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6581-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! elastic fiber assembly GO:0048251 15 9 6,000 1,524E-14 3,668E-11 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 8,000 1,488E-11 1,79E-08 ! collagen metabolic process GO:0032963 45 31 7,000 1,857E-11 1,489E-08 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 7,000 4,203E-11 2,528E-08 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 8,000 1,143E-10 5,5E-08 ! multicellular organismal metabolic process GO:0044236 57 40 7,000 1,722E-10 6,906E-08 ! interphase of mitotic cell cycle GO:0051329 209 95 9,000 6,44E-10 2,214E-07 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 5,000 7,955E-10 2,393E-07 ! interphase GO:0051325 213 98 9,000 8,777E-10 2,346E-07 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 4,000 4,839E-09 1,164E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! phospholipid dephosphorylation GO:0046839 12 5 3,000 8,478E-09 1,854E-06 ! extracellular matrix organization GO:0030198 133 66 7,000 1,114E-08 2,234E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 2,531E-08 4,683E-06 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 5,875E-08 1,01E-05 ! aging GO:0007568 103 55 6,000 6,681E-08 1,072E-05 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 1,169E-07 1,758E-05 ! regulation of intracellular protein transport GO:0033157 80 42 5,000 2,947E-07 4,171E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 4,000 3,308E-07 4,422E-05 GO:0010810|regulation of cell-substrate adhesion, ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 3,471E-07 4,396E-05 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 3,000 3,471E-07 4,176E-05 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 5,000 5,151E-07 5,901E-05 ! meiosis GO:0007126 121 74 6,000 5,341E-07 5,841E-05 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 6,000 5,859E-07 6,129E-05 ! positive regulation of cell cycle GO:0045787 89 48 5,000 6,676E-07 6,692E-05 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 4,000 7,772E-07 7,48E-05 ! embryonic skeletal system development GO:0048706 85 51 5,000 9,64E-07 8,921E-05 ! regulation of angiogenesis GO:0045765 114 52 5,000 1,084E-06 9,659E-05 ! regulation of mRNA stability GO:0043488 31 13 3,000 1,164E-06 1E-04 ! negative regulation of growth GO:0045926 155 84 6,000 1,273E-06 1,056E-04 ! regulation of RNA stability GO:0043487 32 14 3,000 1,621E-06 1,3E-04 ! regulation of intracellular transport GO:0032386 101 57 5,000 1,881E-06 1,46E-04 ! regulation of cell cycle process GO:0010564 149 90 6,000 2,032E-06 1,528E-04 ! skeletal system morphogenesis GO:0048705 105 59 5,000 2,31E-06 1,685E-04 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 4,000 2,997E-06 2,121E-04 ! negative regulation of cell adhesion GO:0007162 81 35 4,000 2,997E-06 2,06E-04 ! embryonic skeletal system morphogenesis GO:0048704 59 35 4,000 2,997E-06 2,003E-04 ! endothelial cell migration GO:0043542 28 17 3,000 3,797E-06 2,469E-04 ! inositol metabolic process GO:0006020 28 17 3,000 3,797E-06 2,404E-04 ! cardiac muscle tissue development GO:0048738 31 17 3,000 3,797E-06 2,342E-04 ! regulation of protein stability GO:0031647 73 37 4,000 3,982E-06 2,395E-04 ! cell cycle arrest GO:0007050 213 100 6,000 4,123E-06 2,42E-04 ! negative regulation of cell growth GO:0030308 132 67 5,000 4,902E-06 2,808E-04 ! male meiosis GO:0007140 7 6 2,000 5,27E-06 2,949E-04 ! negative regulation of cell size GO:0045792 134 69 5,000 5,826E-06 3,186E-04 ! dorsal/ventral pattern formation GO:0009953 68 41 4,000 6,703E-06 3,584E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 3,000 7,613E-06 3,982E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 9,178E-06 4,698E-04 ! cranial nerve morphogenesis GO:0021602 11 7 2,000 9,178E-06 4,6E-04 ! double-strand break repair GO:0006302 81 44 4,000 9,562E-06 4,695E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 1,07E-05 5,149E-04 ! positive regulation of intracellular transport GO:0032388 37 22 3,000 1,138E-05 5,367E-04 ! negative regulation of cell migration GO:0030336 115 46 4,000 1,194E-05 5,526E-04 ! ER overload response GO:0006983 12 8 2,000 1,461E-05 6,634E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,461E-05 6,512E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,461E-05 6,393E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 1,461E-05 6,279E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 1,636E-05 6,906E-04 ! regulation of oxidoreductase activity GO:0051341 46 24 3,000 1,636E-05 6,787E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 3,000 1,938E-05 7,902E-04 ! negative regulation of DNA replication GO:0008156 42 25 3,000 1,938E-05 7,771E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 2,182E-05 8,605E-04 ! regulation of protein transport GO:0051223 154 87 5,000 2,228E-05 8,648E-04 GO:0070201|regulation of establishment of protein localization, ! insulin receptor signaling pathway GO:0008286 64 26 3,000 2,279E-05 8,702E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 2,279E-05 8,566E-04 GO:0045936|negative regulation of phosphate metabolic process, ! gland development GO:0048732 206 88 5,000 2,379E-05 8,805E-04 ! response to UV GO:0009411 104 53 4,000 2,41E-05 8,787E-04 ! regulation of cell adhesion GO:0030155 212 89 5,000 2,537E-05 9,111E-04 ! negative regulation of cell motion GO:0051271 134 55 4,000 2,891E-05 1,023E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 3,102E-05 1,082E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 3,102E-05 1,066E-03 ! positive regulation of cell migration GO:0030335 126 57 4,000 3,444E-05 1,167E-03 ! lipid modification GO:0030258 97 57 4,000 3,444E-05 1,151E-03 ! forebrain development GO:0030900 188 95 5,000 3,674E-05 1,211E-03 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 4,093E-05 1,331E-03 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 4,133E-05 1,326E-03 ! regulation of protein localization GO:0032880 176 97 5,000 4,133E-05 1,309E-03 ! thyroid gland development GO:0030878 26 11 2,000 4,245E-05 1,326E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 4,245E-05 1,309E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 4,245E-05 1,293E-03 ! embryonic gut development GO:0048566 15 11 2,000 4,245E-05 1,277E-03 ! kidney development GO:0001822 122 60 4,000 4,422E-05 1,314E-03 ! metanephros development GO:0001656 74 32 3,000 5,317E-05 1,56E-03 ! regulation of protein import into nucleus GO:0042306 63 32 3,000 5,317E-05 1,541E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 5,633E-05 1,613E-03 ! cranial nerve development GO:0021545 20 12 2,000 5,633E-05 1,594E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 5,633E-05 1,576E-03 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of gene-specific transcription GO:0043193 65 33 3,000 6,02E-05 1,665E-03 ! positive regulation of cell motion GO:0051272 146 64 4,000 6,046E-05 1,653E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 7,287E-05 1,97E-03 GO:0000725|recombinational repair, ! response to X-ray GO:0010165 25 13 2,000 7,287E-05 1,948E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 7,287E-05 1,927E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 3,000 7,625E-05 1,994E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 3,000 8,535E-05 2,208E-03 ! embryonic organ development GO:0048568 57 36 3,000 8,535E-05 2,185E-03 ! urogenital system development GO:0001655 137 69 4,000 8,681E-05 2,199E-03 ! regulation of S phase GO:0033261 23 14 2,000 9,231E-05 2,313E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 9,231E-05 2,29E-03 GO:0060675|ureteric bud morphogenesis, ! response to gamma radiation GO:0010332 28 14 2,000 9,231E-05 2,266E-03 ! respiratory tube development GO:0030323 150 70 4,000 9,3E-05 2,26E-03 ! meiosis I GO:0007127 65 37 3,000 9,521E-05 2,291E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 9,521E-05 2,268E-03 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 1,064E-04 2,51E-03 ! heterophilic cell adhesion GO:0007157 39 15 2,000 1,148E-04 2,682E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 2,000 1,148E-04 2,657E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 2,000 1,148E-04 2,631E-03 ! mammary gland development GO:0030879 86 39 3,000 1,174E-04 2,664E-03 ! ear morphogenesis GO:0042471 60 39 3,000 1,174E-04 2,639E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 1,407E-04 3,134E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,407E-04 3,105E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 1,407E-04 3,077E-03 ! polyol metabolic process GO:0019751 66 41 3,000 1,431E-04 3,101E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 4,000 1,652E-04 3,549E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,726E-04 3,675E-03 ! protein import into nucleus GO:0006606 158 80 4,000 1,753E-04 3,7E-03 ! nuclear import GO:0051170 161 81 4,000 1,859E-04 3,889E-03 ! JAK-STAT cascade GO:0007259 71 44 3,000 1,889E-04 3,918E-03 ! response to retinoic acid GO:0032526 26 18 2,000 2,03E-04 4,175E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 2,03E-04 4,139E-03 ! nerve development GO:0021675 28 18 2,000 2,03E-04 4,105E-03 ! regulation of ligase activity GO:0051340 142 84 4,000 2,205E-04 4,421E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 2,248E-04 4,47E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 2,248E-04 4,433E-03 ! positive regulation of protein transport GO:0051222 72 46 3,000 2,248E-04 4,397E-03 ! response to vitamin A GO:0033189 27 19 2,000 2,399E-04 4,655E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 2,399E-04 4,618E-03 ! protein localization in nucleus GO:0034504 176 87 4,000 2,598E-04 4,961E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 2,653E-04 5,027E-03 ! response to vitamin GO:0033273 31 20 2,000 2,809E-04 5,281E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,809E-04 5,24E-03 ! negative regulation of angiogenesis GO:0016525 45 20 2,000 2,809E-04 5,199E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,809E-04 5,16E-03 ! DNA-dependent DNA replication GO:0006261 74 49 3,000 2,875E-04 5,24E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 3,262E-04 5,901E-03 ! cell aging GO:0007569 44 21 2,000 3,262E-04 5,857E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 2,000 3,262E-04 5,814E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 3,262E-04 5,771E-03 ! gut development GO:0048565 39 21 2,000 3,262E-04 5,729E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 3,357E-04 5,852E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 3,000 3,357E-04 5,81E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,759E-04 6,46E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 3,759E-04 6,414E-03 ! ureteric bud development GO:0001657 43 22 2,000 3,759E-04 6,369E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 4,118E-04 6,928E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 4,118E-04 6,88E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 4,118E-04 6,832E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 4,118E-04 6,786E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 4,118E-04 6,74E-03 ! microvillus organization GO:0032528 7 5 1,000 4,118E-04 6,694E-03 GO:0030033|microvillus assembly, ! muscle cell migration GO:0014812 8 5 1,000 4,118E-04 6,649E-03 ! mRNA transcription GO:0009299 9 5 1,000 4,118E-04 6,605E-03 ! nerve growth factor processing GO:0032455 8 5 1,000 4,118E-04 6,561E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 4,118E-04 6,518E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,118E-04 6,475E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 4,118E-04 6,433E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 4,118E-04 6,392E-03 ! mitotic recombination GO:0006312 9 5 1,000 4,118E-04 6,351E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 4,118E-04 6,31E-03 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 1,000 4,118E-04 6,27E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 4,118E-04 6,231E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 4,118E-04 6,192E-03 ! stem cell division GO:0017145 11 5 1,000 4,118E-04 6,153E-03 GO:0048103|somatic stem cell division, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 2,000 4,302E-04 6,39E-03 ! nucleotide-excision repair GO:0006289 83 56 3,000 4,811E-04 7,101E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 4,811E-04 7,058E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 4,894E-04 7,136E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 5,534E-04 8,022E-03 ! negative regulation of cell development GO:0010721 73 25 2,000 5,534E-04 7,974E-03 GO:0050768|negative regulation of neurogenesis, ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 6,15E-04 8,808E-03 ! forebrain regionalization GO:0021871 8 6 1,000 6,15E-04 8,756E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 6,15E-04 8,704E-03 ! toxin metabolic process GO:0009404 11 6 1,000 6,15E-04 8,653E-03 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 1,000 6,15E-04 8,603E-03 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 6,15E-04 8,553E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 6,15E-04 8,504E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 6,15E-04 8,456E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! establishment of spindle localization GO:0051293 12 6 1,000 6,15E-04 8,408E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 6,15E-04 8,36E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 1,000 6,15E-04 8,313E-03 ! response to UV-C GO:0010225 11 6 1,000 6,15E-04 8,267E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 6,15E-04 8,221E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 6,15E-04 8,175E-03 ! ectodermal gut morphogenesis GO:0048567 12 6 1,000 6,15E-04 8,13E-03 GO:0007439|ectodermal gut development, ! negative regulation of B cell activation GO:0050869 13 6 1,000 6,15E-04 8,086E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 6,227E-04 8,142E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 6,227E-04 8,098E-03 ! cellular response to oxidative stress GO:0034599 39 26 2,000 6,227E-04 8,054E-03 ! positive regulation of nuclear division GO:0051785 40 26 2,000 6,227E-04 8,011E-03 GO:0045840|positive regulation of mitosis, ! DNA damage response, signal transduction GO:0042770 128 60 3,000 6,26E-04 8,011E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 6,26E-04 7,969E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 6,665E-04 8,44E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 6,972E-04 8,782E-03 ! negative regulation of neuron differentiation GO:0045665 42 27 2,000 6,972E-04 8,736E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 6,972E-04 8,691E-03 ! ear development GO:0043583 103 62 3,000 7,089E-04 8,792E-03 ! regulation of mitosis GO:0007088 105 63 3,000 7,532E-04 9,293E-03 GO:0051783|regulation of nuclear division, ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 7,771E-04 9,54E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 8,574E-04 0,010471 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 8,574E-04 0,01041811 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 8,574E-04 0,01036576 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 8,574E-04 0,01031393 ! mRNA stabilization GO:0048255 18 7 1,000 8,574E-04 0,01026262 GO:0043489|RNA stabilization, ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 1,000 8,574E-04 0,01021181 ! spinal cord patterning GO:0021511 13 7 1,000 8,574E-04 0,01016151 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 8,574E-04 0,0101117 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 8,574E-04 0,01006237 ! centrosome duplication GO:0051298 13 7 1,000 8,574E-04 0,01001353 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 8,574E-04 9,965E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 8,574E-04 9,917E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 8,574E-04 9,87E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 8,574E-04 9,823E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 8,574E-04 9,776E-03 ! response to tumor cell GO:0002347 13 7 1,000 8,574E-04 9,73E-03 ! embryonic heart tube development GO:0035050 10 7 1,000 8,574E-04 9,684E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 8,627E-04 9,699E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 9,499E-04 0,01062988 ! lung development GO:0030324 144 67 3,000 9,499E-04 0,01058067 ! cell junction assembly GO:0034329 78 30 2,000 9,54E-04 0,01057731 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 9,54E-04 0,01052879 ! regulation of B cell activation GO:0050864 50 30 2,000 9,54E-04 0,01048071 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,004E-03 0,01098224 ! inner ear morphogenesis GO:0042472 47 31 2,000 1,051E-03 0,0114441 ! cell cycle checkpoint GO:0000075 137 69 3,000 1,061E-03 0,01149514 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 1,061E-03 0,0114436 ! appendage morphogenesis GO:0035107 135 70 3,000 1,119E-03 0,01202242 GO:0035108|limb morphogenesis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,138E-03 0,01217183 ! signal peptide processing GO:0006465 12 8 1,000 1,138E-03 0,01211797 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,138E-03 0,01206459 ! hemoglobin metabolic process GO:0020027 13 8 1,000 1,138E-03 0,01201167 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,138E-03 0,01195922 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,138E-03 0,01190722 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,138E-03 0,01185568 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,138E-03 0,01180457 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,138E-03 0,01175391 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,138E-03 0,01170368 ! blastocyst growth GO:0001832 19 8 1,000 1,138E-03 0,01165388 ! spindle organization GO:0007051 46 32 2,000 1,154E-03 0,01176927 ! response to ionizing radiation GO:0010212 65 32 2,000 1,154E-03 0,01171961 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,154E-03 0,01167037 ! appendage development GO:0048736 136 71 3,000 1,18E-03 0,01188077 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 3,000 1,243E-03 0,01246448 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 1,243E-03 0,01241276 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 1,243E-03 0,01236147 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,243E-03 0,0123106 ! respiratory system development GO:0060541 153 72 3,000 1,243E-03 0,01226015 ! cell fate specification GO:0001708 52 33 2,000 1,264E-03 0,01241151 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,264E-03 0,01236105 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,377E-03 0,01341023 ! cell-matrix adhesion GO:0007160 163 75 3,000 1,447E-03 0,014038 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,457E-03 0,01408088 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,457E-03 0,01402455 ! regulation of glycolysis GO:0006110 21 9 1,000 1,457E-03 0,01396868 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 1,457E-03 0,01391325 ! microtubule bundle formation GO:0001578 21 9 1,000 1,457E-03 0,01385825 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,457E-03 0,01380369 ! motor axon guidance GO:0008045 16 9 1,000 1,457E-03 0,01374956 ! gas homeostasis GO:0033483 16 9 1,000 1,457E-03 0,01369585 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 1,457E-03 0,01364256 ! induction of an organ GO:0001759 14 9 1,000 1,457E-03 0,01358968 ! S phase GO:0051320 9 9 1,000 1,457E-03 0,01353721 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,457E-03 0,01348515 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,457E-03 0,01343348 ! telencephalon development GO:0021537 68 35 2,000 1,502E-03 0,01379111 ! positive regulation of ligase activity GO:0051351 124 77 3,000 1,595E-03 0,01459126 ! cell junction organization GO:0034330 86 36 2,000 1,631E-03 0,01486016 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,631E-03 0,01480409 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,631E-03 0,01474843 ! protein oligomerization GO:0051259 139 78 3,000 1,673E-03 0,01507379 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,753E-03 0,01573937 ! tissue remodeling GO:0048771 76 37 2,000 1,766E-03 0,01579563 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,766E-03 0,01573713 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,814E-03 0,01610338 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,814E-03 0,01604417 ! smoothened signaling pathway GO:0007224 16 10 1,000 1,814E-03 0,0159854 ! lung alveolus development GO:0048286 26 10 1,000 1,814E-03 0,01592706 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,814E-03 0,01586914 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,814E-03 0,01581165 ! multicellular organism growth GO:0035264 18 10 1,000 1,814E-03 0,01575457 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 1,814E-03 0,01569789 ! regulation of bone resorption GO:0045124 25 10 1,000 1,814E-03 0,01564163 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,814E-03 0,01558577 GO:0045685|regulation of glial cell differentiation, ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,814E-03 0,0155303 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,814E-03 0,01547523 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,814E-03 0,01542055 ! localization within membrane GO:0051668 20 10 1,000 1,814E-03 0,01536625 ! nucleus organization GO:0006997 67 38 2,000 1,908E-03 0,01611015 ! response to hypoxia GO:0001666 171 81 3,000 1,922E-03 0,01616863 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,922E-03 0,01611229 ! regulation of neuron differentiation GO:0045664 167 81 3,000 1,922E-03 0,01605635 ! response to nutrient GO:0007584 125 82 3,000 2,01E-03 0,01673727 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 2,01E-03 0,01667955 ! response to oxygen levels GO:0070482 176 83 3,000 2,102E-03 0,0173766 ! negative regulation of muscle development GO:0048635 20 11 1,000 2,207E-03 0,0181887 ! neuron fate specification GO:0048665 17 11 1,000 2,207E-03 0,01812662 ! blood vessel remodeling GO:0001974 29 11 1,000 2,207E-03 0,01806497 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,207E-03 0,01800373 ! ventral spinal cord development GO:0021517 21 11 1,000 2,207E-03 0,01794291 ! telomere maintenance via telomerase GO:0007004 21 11 1,000 2,207E-03 0,01788249 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of intracellular pH GO:0051453 19 11 1,000 2,207E-03 0,01782249 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 2,207E-03 0,01776288 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 2,207E-03 0,01770367 ! DNA methylation GO:0006306 19 11 1,000 2,207E-03 0,01764485 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 24 11 1,000 2,207E-03 0,01758643 ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,207E-03 0,01752838 ! oocyte differentiation GO:0009994 18 11 1,000 2,207E-03 0,01747073 ! thymus development GO:0048538 27 11 1,000 2,207E-03 0,01741344 ! developmental induction GO:0031128 19 11 1,000 2,207E-03 0,01735654 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of binding GO:0051100 72 40 2,000 2,214E-03 0,01735032 ! cytokinesis GO:0000910 72 40 2,000 2,214E-03 0,01729399 ! response to unfolded protein GO:0006986 131 85 3,000 2,293E-03 0,01785142 ! regulation of T cell proliferation GO:0042129 71 41 2,000 2,377E-03 0,01845126 ! regulation of T cell differentiation GO:0045580 70 41 2,000 2,377E-03 0,01839193 ! tube morphogenesis GO:0035239 176 86 3,000 2,392E-03 0,0184496 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 2,548E-03 0,0195871 ! regulation of DNA binding GO:0051101 155 88 3,000 2,601E-03 0,01993009 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,638E-03 0,02014672 ! cartilage condensation GO:0001502 20 12 1,000 2,638E-03 0,02008296 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,638E-03 0,02001961 GO:0050927|positive regulation of positive chemotaxis, ! hippocampus development GO:0021766 26 12 1,000 2,638E-03 0,01995666 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,638E-03 0,0198941 ! cytokine biosynthetic process GO:0042089 21 12 1,000 2,638E-03 0,01983193 ! regulation of exit from mitosis GO:0007096 17 12 1,000 2,638E-03 0,01977014 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 2,638E-03 0,01970875 ! focal adhesion formation GO:0048041 35 12 1,000 2,638E-03 0,01964773 ! entry into host cell GO:0030260 32 12 1,000 2,638E-03 0,01958709 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 2,638E-03 0,01952682 ! mRNA polyadenylation GO:0006378 23 12 1,000 2,638E-03 0,01946692 ! autonomic nervous system development GO:0048483 24 12 1,000 2,638E-03 0,01940739 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 2,638E-03 0,01934822 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,638E-03 0,01928941 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,638E-03 0,01923096 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,638E-03 0,01917286 ! neural tube development GO:0021915 77 43 2,000 2,726E-03 0,0197573 ! developmental growth GO:0048589 82 44 2,000 2,912E-03 0,02103942 ! response to protein stimulus GO:0051789 149 91 3,000 2,937E-03 0,02115498 ! regulation of chemokine production GO:0032642 18 13 1,000 3,104E-03 0,02229312 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 3,104E-03 0,02222677 ! cytokine metabolic process GO:0042107 22 13 1,000 3,104E-03 0,02216081 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,104E-03 0,02209525 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! RNA-dependent DNA replication GO:0006278 23 13 1,000 3,104E-03 0,02203007 ! regulation of cellular pH GO:0030641 22 13 1,000 3,104E-03 0,02196528 ! mRNA 3'-end processing GO:0031124 24 13 1,000 3,104E-03 0,02190086 ! embryonic placenta development GO:0001892 23 13 1,000 3,104E-03 0,02183683 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 3,104E-03 0,02177316 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 3,105E-03 0,02171835 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 3,176E-03 0,02215111 ! protein homooligomerization GO:0051260 76 47 2,000 3,515E-03 0,02444184 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,606E-03 0,02500253 ! non-recombinational repair GO:0000726 25 14 1,000 3,606E-03 0,02493068 GO:0006303|double-strand break repair via nonhomologous end joining, ! RNA polyadenylation GO:0043631 30 14 1,000 3,606E-03 0,02485925 ! regulation of mRNA processing GO:0050684 24 14 1,000 3,606E-03 0,02478822 ! embryo implantation GO:0007566 30 14 1,000 3,606E-03 0,0247176 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 3,606E-03 0,02464738 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,606E-03 0,02457756 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 3,606E-03 0,02450813 ! activation of caspase activity GO:0006919 84 48 2,000 3,732E-03 0,02529044 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 3,732E-03 0,0252194 ! endocrine system development GO:0035270 104 49 2,000 3,956E-03 0,02666253 ! skeletal muscle tissue development GO:0007519 186 99 3,000 3,974E-03 0,02670944 GO:0060538|skeletal muscle organ development, ! negative regulation of bone remodeling GO:0046851 33 15 1,000 4,143E-03 0,02776636 ! G1/S transition checkpoint GO:0031575 40 15 1,000 4,143E-03 0,02768923 ! muscle maintenance GO:0046716 26 15 1,000 4,143E-03 0,02761253 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 4,143E-03 0,02753625 ! peptide hormone processing GO:0016486 23 15 1,000 4,143E-03 0,02746039 ! inner ear development GO:0048839 79 50 2,000 4,189E-03 0,02768775 ! negative regulation of immune system process GO:0002683 95 50 2,000 4,189E-03 0,0276119 ! viral infectious cycle GO:0019058 99 51 2,000 4,43E-03 0,02911957 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 4,679E-03 0,03067297 ! cartilage development GO:0051216 90 52 2,000 4,679E-03 0,03058962 ! synapse organization GO:0050808 85 52 2,000 4,679E-03 0,03050672 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,715E-03 0,0306589 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 4,715E-03 0,03057626 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 4,715E-03 0,03049406 GO:0031114|regulation of microtubule depolymerization, ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 4,715E-03 0,03041231 ! neuron recognition GO:0008038 35 16 1,000 4,715E-03 0,030331 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,715E-03 0,03025011 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,715E-03 0,03016966 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 5,321E-03 0,03395694 ! limbic system development GO:0021761 36 17 1,000 5,321E-03 0,0338671 ! heart looping GO:0001947 30 17 1,000 5,321E-03 0,03377774 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 5,321E-03 0,03368886 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 5,321E-03 0,03360043 ! DNA unwinding during replication GO:0006268 27 17 1,000 5,321E-03 0,03351247 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 5,321E-03 0,03342497 ! neural crest cell migration GO:0001755 37 17 1,000 5,321E-03 0,03333793 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 5,321E-03 0,03325134 ! RNA 3'-end processing GO:0031123 34 17 1,000 5,321E-03 0,03316519 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 5,321E-03 0,0330795 ! positive regulation of caspase activity GO:0043280 95 55 2,000 5,476E-03 0,03395696 GO:0010952|positive regulation of peptidase activity, ! skeletal muscle fiber development GO:0048741 111 56 2,000 5,759E-03 0,03561839 ! positive regulation of organelle organization GO:0010638 100 56 2,000 5,759E-03 0,03552706 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,96E-03 0,03667757 ! memory GO:0007613 31 18 1,000 5,96E-03 0,036584 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 5,96E-03 0,03649091 GO:0050886|endocrine process, ! centrosome cycle GO:0007098 25 18 1,000 5,96E-03 0,0363983 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 5,96E-03 0,03630615 ! peptide biosynthetic process GO:0043043 24 18 1,000 5,96E-03 0,03621447 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,96E-03 0,03612325 ! muscle fiber development GO:0048747 112 57 2,000 6,05E-03 0,03657411 ! protein secretion GO:0009306 39 19 1,000 6,633E-03 0,04000045 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 6,633E-03 0,03990045 ! lipid phosphorylation GO:0046834 35 19 1,000 6,633E-03 0,03980095 ! forelimb morphogenesis GO:0035136 32 19 1,000 6,633E-03 0,03970194 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 6,633E-03 0,03960343 ! actin filament bundle formation GO:0051017 42 19 1,000 6,633E-03 0,0395054 ! neuromuscular junction development GO:0007528 34 19 1,000 6,633E-03 0,03940785 ! plasma membrane fusion GO:0045026 28 19 1,000 6,633E-03 0,03931079 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 6,633E-03 0,0392142 ! G1 phase GO:0051318 40 19 1,000 6,633E-03 0,03911809 ! proximal/distal pattern formation GO:0009954 32 19 1,000 6,633E-03 0,03902245 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 6,633E-03 0,03892727 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 6,659E-03 0,03898074 ! protein amino acid acetylation GO:0006473 39 20 1,000 7,339E-03 0,04286027 ! transcription from RNA polymerase III promoter GO:0006383 41 20 1,000 7,339E-03 0,04275649 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 7,339E-03 0,04265322 GO:0010675|regulation of cellular carbohydrate metabolic process, ! DNA duplex unwinding GO:0032508 31 20 1,000 7,339E-03 0,04255044 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 1,000 7,339E-03 0,04244815 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 7,339E-03 0,04234636 ! peptidyl-serine modification GO:0018209 43 20 1,000 7,339E-03 0,04224505 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 7,339E-03 0,04214423 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 7,339E-03 0,04204389 ! viral reproductive process GO:0022415 126 62 2,000 7,638E-03 0,04365071 ! regulation of homeostatic process GO:0032844 134 62 2,000 7,638E-03 0,04354727 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 7,982E-03 0,04540233 ! hindlimb morphogenesis GO:0035137 43 21 1,000 8,078E-03 0,04583632 ! axis specification GO:0009798 38 21 1,000 8,078E-03 0,04572847 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 8,078E-03 0,04562113 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 8,078E-03 0,04551429 ! oogenesis GO:0048477 36 21 1,000 8,078E-03 0,04540795 ! DNA modification GO:0006304 34 21 1,000 8,078E-03 0,0453021 ! positive regulation of locomotion GO:0040017 39 21 1,000 8,078E-03 0,04519675 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! embryonic limb morphogenesis GO:0030326 125 65 2,000 8,698E-03 0,04855419 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 8,848E-03 0,0492769 ! regulation of chemotaxis GO:0050920 40 22 1,000 8,848E-03 0,04916309 ! central nervous system neuron development GO:0021954 46 22 1,000 8,848E-03 0,04904981 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 8,848E-03 0,04893705 ! apoptotic nuclear changes GO:0030262 32 22 1,000 8,848E-03 0,04882481 ! renal system process GO:0003014 41 22 1,000 8,848E-03 0,04871309 ! positive regulation of B cell activation GO:0050871 38 22 1,000 8,848E-03 0,04860187 ! activation of JUN kinase activity GO:0007257 42 22 1,000 8,848E-03 0,04849116 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 8,848E-03 0,04838095 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 8,848E-03 0,04827124 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 9,45E-03 0,05143944 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 9,649E-03 0,05240728 ! leukocyte adhesion GO:0007159 50 23 1,000 9,649E-03 0,05228925 ! regulation of DNA recombination GO:0000018 48 23 1,000 9,649E-03 0,05217174 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 9,649E-03 0,05205477 ! negative regulation of ligase activity GO:0051352 112 68 2,000 9,84E-03 0,05296216 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 9,84E-03 0,05284394 ! viral reproduction GO:0016032 134 68 2,000 9,84E-03 0,05272625 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 9,84E-03 0,05260908 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01048212 0,05592012 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 0,01048212 0,0557964 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 0,01048212 0,05567323 ! spinal cord development GO:0021510 47 24 1,000 0,01048212 0,05555061 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 0,01048212 0,05542852 ! regulation of behavior GO:0050795 43 24 1,000 0,01048212 0,05530696 ! pallium development GO:0021543 49 24 1,000 0,01048212 0,05518594 ! protein tetramerization GO:0051262 52 24 1,000 0,01048212 0,05506545 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01134548 0,05947108 ! myelination GO:0042552 45 25 1,000 0,01134548 0,05934179 ! vasculogenesis GO:0001570 46 25 1,000 0,01134548 0,05921307 ! response to starvation GO:0042594 42 25 1,000 0,01134548 0,0590849 ! neural crest cell development GO:0014032 54 25 1,000 0,01134548 0,05895729 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 0,01134548 0,05883023 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 0,01134548 0,05870371 ! somitogenesis GO:0001756 43 25 1,000 0,01134548 0,05857774 ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01134548 0,0584523 ! telomere organization GO:0032200 43 25 1,000 0,01134548 0,0583274 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 1,000 0,01134548 0,05820304 GO:0060606|tube closure, ! liver development GO:0001889 53 25 1,000 0,01134548 0,0580792 ! axon guidance GO:0007411 139 73 2,000 0,01192805 0,06093181 ! initiation of viral infection GO:0019059 57 26 1,000 0,01223905 0,06238803 ! tube lumen formation GO:0035148 50 26 1,000 0,01223905 0,06225613 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 0,01223905 0,06212479 ! microtubule organizing center organization GO:0031023 39 26 1,000 0,01223905 0,061994 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01223905 0,06186376 ! blastocyst development GO:0001824 49 26 1,000 0,01223905 0,06173407 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 0,01223905 0,06160492 ! regulation of transcription factor activity GO:0051090 126 74 2,000 0,01237388 0,06215356 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01282917 0,0643062 ! neuron fate commitment GO:0048663 48 27 1,000 0,0131624 0,06583936 ! response to toxin GO:0009636 47 27 1,000 0,0131624 0,06570276 ! base-excision repair GO:0006284 41 27 1,000 0,0131624 0,06556673 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,0131624 0,06543126 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,0131624 0,06529635 ! protein amino acid acylation GO:0043543 55 27 1,000 0,0131624 0,065162 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,0131624 0,0650282 ! primary neural tube formation GO:0014020 51 27 1,000 0,0131624 0,06489494 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01329394 0,06540944 ! dendrite development GO:0016358 59 28 1,000 0,01411511 0,06930808 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01411511 0,06916693 ! synaptogenesis GO:0007416 42 28 1,000 0,01411511 0,06902634 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01411511 0,06888633 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01411511 0,06874688 ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,01425204 0,06927355 ! regulation of pH GO:0006885 43 29 1,000 0,01509677 0,07323153 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01509677 0,07308418 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01509677 0,07293743 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01509677 0,07279126 ! tissue homeostasis GO:0001894 48 29 1,000 0,01509677 0,07264568 GO:0048871|multicellular organismal homeostasis, ! ensheathment of neurons GO:0007272 57 30 1,000 0,01610697 0,07735206 GO:0008366|axon ensheathment, ! eye morphogenesis GO:0048592 60 30 1,000 0,01610697 0,07719797 ! response to drug GO:0042493 143 82 2,000 0,0162831 0,07788694 ! mRNA export from nucleus GO:0006406 48 31 1,000 0,0171453 0,08184842 ! iron ion homeostasis GO:0055072 54 31 1,000 0,0171453 0,08168634 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,0171453 0,08152491 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,0171453 0,08136411 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of transport GO:0051051 153 84 2,000 0,01735635 0,08220351 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01821136 0,08608358 ! hindbrain development GO:0030902 61 32 1,000 0,01821136 0,08591478 ! mitochondrion organization GO:0007005 148 86 2,000 0,01846825 0,08695616 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01930475 0,09071725 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01930475 0,09054041 ! glial cell differentiation GO:0010001 63 34 1,000 0,02042507 0,09560842 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,02042507 0,09542277 ! mismatch repair GO:0006298 46 34 1,000 0,02042507 0,09523784 ! placenta development GO:0001890 53 34 1,000 0,02042507 0,09505363 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,02042507 0,09487013 ! ossification GO:0001503 188 90 2,000 0,02080827 0,09646375 ! bone development GO:0060348 189 91 2,000 0,02141752 0,09909723 ! regulation of muscle development GO:0048634 70 35 1,000 0,02157194 0,09962013 ! odontogenesis GO:0042476 66 35 1,000 0,02157194 0,09942929 ! female gonad development GO:0008585 58 35 1,000 0,02157194 0,09923918 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02157194 0,09904979 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,02157194 0,09886112 ! cytokine production GO:0001816 59 35 1,000 0,02157194 0,09867317 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,02157194 0,09848594 ! neural tube formation GO:0001841 67 35 1,000 0,02157194 0,09829941 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,02266516 0,10308578 GO:0010498|proteasomal protein catabolic process, ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02274496 0,10325355 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02274496 0,1030591 ! positive regulation of cell development GO:0010720 80 36 1,000 0,02274496 0,10286538 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,02274496 0,10267239 ! regulation of T cell activation GO:0050863 158 94 2,000 0,02330354 0,10499686 ! RNA export from nucleus GO:0006405 56 37 1,000 0,02394376 0,10767979 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02394376 0,1074789 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,02394376 0,10727875 ! glycogen metabolic process GO:0005977 61 37 1,000 0,02394376 0,10707935 ! mRNA transport GO:0051028 169 96 2,000 0,02460942 0,10985208 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02516795 0,11213721 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,02516795 0,11192994 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02516795 0,11172342 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02516795 0,11151767 GO:0046660|female sex differentiation, ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02516795 0,11131267 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02516795 0,11110843 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02516795 0,11090494 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,02516795 0,11070218 GO:0006073|cellular glucan metabolic process, ! protein ubiquitination GO:0016567 217 97 2,000 0,02527691 0,11097857 ! segmentation GO:0035282 67 39 1,000 0,02641716 0,11577358 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02641716 0,11556308 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02769102 0,12091579 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 0,02769102 0,12069674 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 0,02898916 0,12612643 ! gliogenesis GO:0042063 88 41 1,000 0,02898916 0,12589877 ! T cell differentiation GO:0030217 81 41 1,000 0,02898916 0,12567192 ! female gamete generation GO:0007292 61 41 1,000 0,02898916 0,12544589 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03031121 0,13093137 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,03031121 0,13069673 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,03031121 0,13046292 ! neuron migration GO:0001764 79 42 1,000 0,03031121 0,13022996 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,03165682 0,13576881 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,03165682 0,13552723 ! glucose transport GO:0015758 65 43 1,000 0,03165682 0,13528651 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,03165682 0,13504664 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,03165682 0,13480762 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03195932 0,13585534 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03195932 0,13561574 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03195932 0,13537698 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03195932 0,13513905 ! neuron fate determination GO:0048664 7 5 0,000 0,03195932 0,13490197 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03195932 0,13466571 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03195932 0,13443028 ! polyol transport GO:0015791 12 5 0,000 0,03195932 0,13419568 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03195932 0,13396189 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03195932 0,13372891 ! response to superoxide GO:0000303 10 5 0,000 0,03195932 0,13349674 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03195932 0,13326538 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03195932 0,13303481 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03195932 0,13280505 ! female meiosis GO:0007143 7 5 0,000 0,03195932 0,13257607 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03195932 0,13234789 ! cobalt ion transport GO:0006824 11 5 0,000 0,03195932 0,13212048 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03195932 0,13189386 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03195932 0,13166802 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03195932 0,13144294 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03195932 0,13121864 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03195932 0,1309951 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03195932 0,13077232 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03195932 0,13055029 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03195932 0,13032902 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03195932 0,1301085 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03195932 0,12988872 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03195932 0,12966968 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03195932 0,12945138 ! negative chemotaxis GO:0050919 14 5 0,000 0,03195932 0,12923382 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03195932 0,12901698 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03195932 0,12880087 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03195932 0,12858549 ! behavioral response to pain GO:0048266 9 5 0,000 0,03195932 0,12837082 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03195932 0,12815687 ! Notch receptor processing GO:0007220 8 5 0,000 0,03195932 0,12794363 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03195932 0,1277311 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03195932 0,12751927 ! micturition GO:0060073 9 5 0,000 0,03195932 0,12730815 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03195932 0,12709772 ! copulation GO:0007620 9 5 0,000 0,03195932 0,12688799 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03195932 0,12667895 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03195932 0,1264706 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03195932 0,12626293 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03195932 0,12605594 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03195932 0,12584963 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03195932 0,12564399 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03195932 0,12543902 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03195932 0,12523473 ! grooming behavior GO:0007625 6 5 0,000 0,03195932 0,12503109 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03195932 0,12482812 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03195932 0,12462581 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03195932 0,12442415 ! response to protozoan GO:0001562 10 5 0,000 0,03195932 0,12422314 ! lymph vessel development GO:0001945 10 5 0,000 0,03195932 0,12402278 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03195932 0,12382306 ! endochondral ossification GO:0001958 16 5 0,000 0,03195932 0,12362399 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03195932 0,12342556 ! parathyroid gland development GO:0060017 13 5 0,000 0,03195932 0,12322776 ! anagen GO:0042640 6 5 0,000 0,03195932 0,1230306 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03195932 0,12283406 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03195932 0,12263815 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03195932 0,12244287 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03195932 0,12224821 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03195932 0,12205416 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03195932 0,12186073 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03195932 0,12166791 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03195932 0,12147571 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03195932 0,1212841 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03195932 0,12109311 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03195932 0,12090271 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03195932 0,12071291 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03195932 0,1205237 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03195932 0,12033509 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03195932 0,12014707 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03195932 0,11995963 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,03195932 0,11977278 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03195932 0,1195865 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03195932 0,11940081 ! histidine catabolic process GO:0006548 6 5 0,000 0,03195932 0,11921569 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03195932 0,11903115 ! valine metabolic process GO:0006573 10 5 0,000 0,03195932 0,11884717 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03195932 0,11866377 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03195932 0,11848093 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03195932 0,11829865 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03195932 0,11811693 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03195932 0,11793577 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03195932 0,11775516 ! polyol catabolic process GO:0046174 7 5 0,000 0,03195932 0,11757511 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03195932 0,11739561 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03195932 0,11721665 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03195932 0,11703824 ! mitochondrial fission GO:0000266 8 5 0,000 0,03195932 0,11686037 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03195932 0,11668304 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03195932 0,11650625 GO:0009253|peptidoglycan catabolic process, ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03195932 0,11632999 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03195932 0,11615426 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03195932 0,11597907 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03195932 0,1158044 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03195932 0,11563026 ! response to food GO:0032094 6 5 0,000 0,03195932 0,11545664 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03195932 0,11528354 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03195932 0,11511096 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03195932 0,1149389 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03195932 0,11476735 ! forebrain neuron development GO:0021884 13 5 0,000 0,03195932 0,11459631 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03195932 0,11442578 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,03195932 0,11425575 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03195932 0,11408623 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03195932 0,11391722 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03195932 0,1137487 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03195932 0,11358068 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03195932 0,11341316 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03195932 0,11324613 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03195932 0,11307959 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03195932 0,11291354 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03195932 0,11274798 ! basic amino acid transport GO:0015802 11 5 0,000 0,03195932 0,1125829 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03195932 0,11241831 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03195932 0,11225419 ! depyrimidination GO:0045008 10 5 0,000 0,03195932 0,11209056 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03195932 0,1119274 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03195932 0,11176471 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03195932 0,1116025 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03195932 0,11144076 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03195932 0,11127948 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03195932 0,11111867 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03195932 0,11095833 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03195932 0,11079845 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03195932 0,11063902 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03195932 0,11048006 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03195932 0,11032155 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03195932 0,1101635 ! response to arsenic GO:0046685 10 5 0,000 0,03195932 0,1100059 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03195932 0,10984875 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03195932 0,10969204 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03195932 0,10953579 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03195932 0,10937997 ! response to cadmium ion GO:0046686 7 5 0,000 0,03195932 0,10922461 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03195932 0,10906968 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03195932 0,10891519 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03195932 0,10876113 ! decidualization GO:0046697 11 5 0,000 0,03195932 0,10860752 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03195932 0,10845433 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03195932 0,10830158 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03195932 0,10814926 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03195932 0,10799736 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03195932 0,10784589 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03195932 0,10769485 ! neural tube patterning GO:0021532 7 5 0,000 0,03195932 0,10754423 ! embryonic cleavage GO:0040016 6 5 0,000 0,03195932 0,10739403 ! peroxisome fission GO:0016559 5 5 0,000 0,03195932 0,10724424 ! histone demethylation GO:0016577 10 5 0,000 0,03195932 0,10709488 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03195932 0,10694593 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03195932 0,10679739 ! metaphase plate congression GO:0051310 7 5 0,000 0,03195932 0,10664927 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03195932 0,10650155 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,03195932 0,10635425 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03195932 0,10620735 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03195932 0,10606086 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03195932 0,10591477 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03195932 0,10576908 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03195932 0,10562379 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03195932 0,10547891 ! plasminogen activation GO:0031639 5 5 0,000 0,03195932 0,10533441 ! B cell homeostasis GO:0001782 13 5 0,000 0,03195932 0,10519032 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03195932 0,10504661 ! metaphase GO:0051323 8 5 0,000 0,03195932 0,1049033 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03195932 0,10476038 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03195932 0,10461785 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03195932 0,10447571 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03195932 0,10433395 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03195932 0,10419258 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03195932 0,10405159 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03195932 0,10391098 ! response to redox state GO:0051775 5 5 0,000 0,03195932 0,10377075 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03195932 0,10363089 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03195932 0,10349142 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03195932 0,10335231 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03195932 0,10321359 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03195932 0,10307523 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03195932 0,10293725 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03195932 0,10279963 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03195932 0,10266238 ! striatum development GO:0021756 9 5 0,000 0,03195932 0,1025255 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03195932 0,10238898 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03195932 0,10225282 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03195932 0,10211703 ! glial cell migration GO:0008347 11 5 0,000 0,03195932 0,10198159 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,03195932 0,10184652 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03195932 0,1017118 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03195932 0,10157744 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03195932 0,10144343 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03195932 0,10130978 ! neuroprotection GO:0043526 6 5 0,000 0,03195932 0,10117648 ! neural plate development GO:0001840 8 5 0,000 0,03195932 0,10104352 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03195932 0,10091092 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03195932 0,10077867 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03195932 0,10064676 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03195932 0,10051519 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03195932 0,10038397 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03195932 0,10025309 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03195932 0,10012255 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03195932 0,09999236 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03195932 0,0998625 ! spindle assembly GO:0051225 6 5 0,000 0,03195932 0,09973297 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03195932 0,09960379 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03195932 0,09947493 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03195932 0,09934641 ! drug metabolic process GO:0017144 6 5 0,000 0,03195932 0,09921822 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03195932 0,09909036 ! organ regeneration GO:0031100 7 5 0,000 0,03195932 0,09896283 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03195932 0,09883563 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03195932 0,09870876 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03195932 0,09858221 ! hexose transport GO:0008645 67 44 1,000 0,03302562 0,1017409 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 1,000 0,03302562 0,1016108 ! B cell differentiation GO:0030183 107 44 1,000 0,03302562 0,10148103 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03302562 0,10135159 ! glycolysis GO:0006096 65 45 1,000 0,03441727 0,10548783 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,0372677 0,11407899 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,0372677 0,11393403 ! JNK cascade GO:0007254 91 47 1,000 0,0372677 0,11378945 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,0372677 0,11364523 ! methylation GO:0032259 90 47 1,000 0,0372677 0,11350137 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03822818 0,11627939 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03822818 0,11613258 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03822818 0,11598613 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03822818 0,11584005 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03822818 0,11569434 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03822818 0,115549 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03822818 0,11540402 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03822818 0,1152594 ! sleep GO:0030431 13 6 0,000 0,03822818 0,11511515 ! response to oxygen radical GO:0000305 11 6 0,000 0,03822818 0,11497125 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03822818 0,11482772 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03822818 0,11468454 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03822818 0,11454172 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03822818 0,11439925 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03822818 0,11425714 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03822818 0,11411539 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03822818 0,11397398 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03822818 0,11383292 ! response to zinc ion GO:0010043 9 6 0,000 0,03822818 0,11369221 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03822818 0,11355185 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03822818 0,11341184 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03822818 0,11327217 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03822818 0,11313284 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03822818 0,11299386 ! malate metabolic process GO:0006108 11 6 0,000 0,03822818 0,11285522 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03822818 0,11271691 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03822818 0,11257895 ! protein refolding GO:0042026 15 6 0,000 0,03822818 0,11244132 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03822818 0,11230403 ! opsonization GO:0008228 8 6 0,000 0,03822818 0,11216707 ! mating behavior GO:0007617 7 6 0,000 0,03822818 0,11203045 ! neuron remodeling GO:0016322 15 6 0,000 0,03822818 0,11189416 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03822818 0,1117582 ! equilibrioception GO:0050957 14 6 0,000 0,03822818 0,11162257 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03822818 0,11148727 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03822818 0,1113523 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03822818 0,11121766 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03822818 0,11108333 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03822818 0,11094934 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03822818 0,11081566 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03822818 0,11068231 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03822818 0,11054928 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03822818 0,11041657 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03822818 0,11028417 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03822818 0,1101521 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03822818 0,11002034 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03822818 0,10988889 ! thymic T cell selection GO:0045061 12 6 0,000 0,03822818 0,10975776 ! protein lipoylation GO:0009249 10 6 0,000 0,03822818 0,10962694 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03822818 0,10949643 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03822818 0,10936623 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03822818 0,10923634 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03822818 0,10910676 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03822818 0,10897749 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03822818 0,10884852 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03822818 0,10871986 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03822818 0,1085915 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03822818 0,10846344 ! hyperosmotic response GO:0006972 9 6 0,000 0,03822818 0,10833569 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03822818 0,10820824 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03822818 0,10808108 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03822818 0,10795423 ! urea metabolic process GO:0019627 7 6 0,000 0,03822818 0,10782767 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03822818 0,10770141 ! neutrophil activation GO:0042119 8 6 0,000 0,03822818 0,10757544 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03822818 0,10744977 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03822818 0,10732439 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03822818 0,1071993 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03822818 0,10707451 ! neuron apoptosis GO:0051402 9 6 0,000 0,03822818 0,10695 ! nucleoside salvage GO:0043174 9 6 0,000 0,03822818 0,10682579 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03822818 0,10670186 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03822818 0,10657822 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03822818 0,10645486 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03822818 0,10633179 ! carnitine transport GO:0015879 10 6 0,000 0,03822818 0,10620901 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03822818 0,10608651 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03822818 0,10596429 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03822818 0,10584235 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03822818 0,10572069 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03822818 0,10559931 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03822818 0,10547821 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03822818 0,10535739 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03822818 0,10523684 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03822818 0,10511657 ! monocyte differentiation GO:0030224 12 6 0,000 0,03822818 0,10499658 ! astrocyte development GO:0014002 15 6 0,000 0,03822818 0,10487685 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03822818 0,1047574 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03822818 0,10463823 ! interaction with symbiont GO:0051702 13 6 0,000 0,03822818 0,10451932 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03822818 0,10440068 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03822818 0,10428231 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03822818 0,10416421 ! response to copper ion GO:0046688 10 6 0,000 0,03822818 0,10404638 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03822818 0,10392881 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03822818 0,10381151 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03822818 0,10369448 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03822818 0,1035777 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03822818 0,10346119 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03822818 0,10334494 ! hair follicle maturation GO:0048820 7 6 0,000 0,03822818 0,10322896 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03822818 0,10311323 ! Schwann cell development GO:0014044 15 6 0,000 0,03822818 0,10299776 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03822818 0,10288255 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03822818 0,1027676 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03822818 0,1026529 ! subpallium development GO:0021544 10 6 0,000 0,03822818 0,10253846 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03822818 0,10242428 ! histone ubiquitination GO:0016574 8 6 0,000 0,03822818 0,10231035 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03822818 0,10219667 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03822818 0,10208324 ! G2 phase GO:0051319 16 6 0,000 0,03822818 0,10197007 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03822818 0,10185714 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03822818 0,10174447 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03822818 0,10163205 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03822818 0,10151987 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03822818 0,10140794 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03822818 0,10129626 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03822818 0,10118482 ! receptor internalization GO:0031623 10 6 0,000 0,03822818 0,10107363 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03822818 0,10096268 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03822818 0,10085197 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03822818 0,10074151 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03822818 0,10063129 ! protein deubiquitination GO:0016579 14 6 0,000 0,03822818 0,10052131 ! protein destabilization GO:0031648 9 6 0,000 0,03822818 0,10041157 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03822818 0,10030207 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03822818 0,10019281 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03822818 0,10008379 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03822818 0,099975 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03822818 0,09986645 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03822818 0,09975814 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03822818 0,09965006 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03822818 0,09954221 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03822818 0,0994346 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03822818 0,09932721 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03822818 0,09922007 ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03822818 0,09911315 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03822818 0,09900646 ! catecholamine transport GO:0051937 9 6 0,000 0,03822818 0,0989 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03822818 0,09879377 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03822818 0,09868777 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03822818 0,09858199 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03822818 0,09847645 ! maternal placenta development GO:0001893 12 6 0,000 0,03822818 0,09837112 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03822818 0,09826603 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03822818 0,09816115 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03822818 0,0980565 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03822818 0,09795208 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03822818 0,09784787 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03822818 0,09774389 ! mitochondrial transport GO:0006839 82 48 1,000 0,03872579 0,0989111 ! cellular component disassembly GO:0022411 86 48 1,000 0,03872579 0,09880621 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,03872579 0,09870154 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03872579 0,0985971 ! regulation of action potential GO:0001508 95 49 1,000 0,04020535 0,10225589 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,04020535 0,10214792 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,04020535 0,10204017 ! peptide metabolic process GO:0006518 76 49 1,000 0,04020535 0,10193264 ! histone modification GO:0016570 91 50 1,000 0,04170604 0,10562603 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,04170604 0,10551497 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,04170604 0,10540413 ! positive regulation of binding GO:0051099 78 51 1,000 0,04322752 0,10913476 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,04322752 0,10902036 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,04322752 0,1089062 ! regulation of cell shape GO:0008360 125 51 1,000 0,04322752 0,10879229 ! tRNA transcription GO:0009304 14 7 0,000 0,04445665 0,11176876 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04445665 0,11165209 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04445665 0,11153567 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04445665 0,11141948 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04445665 0,11130354 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04445665 0,11118784 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04445665 0,11107238 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04445665 0,11095716 ! prostate gland development GO:0030850 13 7 0,000 0,04445665 0,11084218 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04445665 0,11072744 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04445665 0,11061293 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04445665 0,11049866 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04445665 0,11038463 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04445665 0,11027083 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04445665 0,11015726 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04445665 0,11004393 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04445665 0,10993084 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04445665 0,10981797 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04445665 0,10970534 ! glycolipid transport GO:0046836 10 7 0,000 0,04445665 0,10959293 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04445665 0,10948076 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04445665 0,10936882 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04445665 0,1092571 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04445665 0,10914562 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04445665 0,10903436 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04445665 0,10892332 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04445665 0,10881252 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04445665 0,10870193 ! pericardium development GO:0060039 14 7 0,000 0,04445665 0,10859158 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04445665 0,10848144 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04445665 0,10837153 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04445665 0,10826185 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04445665 0,10815238 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04445665 0,10804313 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04445665 0,10793411 ! lipoprotein transport GO:0042953 14 7 0,000 0,04445665 0,10782531 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04445665 0,10771672 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04445665 0,10760835 ! rhythmic behavior GO:0007622 15 7 0,000 0,04445665 0,1075002 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04445665 0,10739227 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04445665 0,10728456 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04445665 0,10717706 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04445665 0,10706977 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04445665 0,1069627 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04445665 0,10685585 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04445665 0,1067492 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04445665 0,10664277 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04445665 0,10653656 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04445665 0,10643055 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04445665 0,10632475 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04445665 0,10621917 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04445665 0,10611379 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04445665 0,10600863 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04445665 0,10590367 ! adrenal gland development GO:0030325 17 7 0,000 0,04445665 0,10579892 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04445665 0,10569437 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04445665 0,10559003 ! ovulation GO:0030728 9 7 0,000 0,04445665 0,1054859 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04445665 0,10538197 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04445665 0,10527825 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04445665 0,10517473 ! microtubule nucleation GO:0007020 20 7 0,000 0,04445665 0,10507142 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04445665 0,10496831 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04445665 0,1048654 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04445665 0,10476269 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04445665 0,10466018 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04445665 0,10455787 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04445665 0,10445576 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04445665 0,10435386 ! galactose metabolic process GO:0006012 13 7 0,000 0,04445665 0,10425215 ! vesicle fusion GO:0006906 17 7 0,000 0,04445665 0,10415064 ! response to dietary excess GO:0002021 8 7 0,000 0,04445665 0,10404932 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04445665 0,10394821 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04445665 0,10384728 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04445665 0,10374656 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04445665 0,10364603 ! organ growth GO:0035265 15 7 0,000 0,04445665 0,1035457 ! purine salvage GO:0043101 10 7 0,000 0,04445665 0,10344555 ! nucleoside transport GO:0015858 8 7 0,000 0,04445665 0,10334561 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04445665 0,10324585 ! parturition GO:0007567 14 7 0,000 0,04445665 0,10314629 ! rRNA modification GO:0000154 14 7 0,000 0,04445665 0,10304692 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04445665 0,10294774 ! spindle checkpoint GO:0031577 15 7 0,000 0,04445665 0,10284875 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04445665 0,10274996 ! macrophage differentiation GO:0030225 11 7 0,000 0,04445665 0,10265135 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04445665 0,10255293 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04445665 0,1024547 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04445665 0,10235665 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04445665 0,1022588 ! fibrinolysis GO:0042730 10 7 0,000 0,04445665 0,10216113 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04445665 0,10206365 ! eating behavior GO:0042755 7 7 0,000 0,04445665 0,10196635 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04445665 0,10186924 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04445665 0,10177232 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04445665 0,10167557 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04445665 0,10157902 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04445665 0,10148264 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04445665 0,10138645 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04445665 0,10129044 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04445665 0,10119461 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04445665 0,10109896 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04445665 0,1010035 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04445665 0,10090821 ! regulation of meiosis GO:0040020 12 7 0,000 0,04445665 0,1008131 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04445665 0,10071818 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04445665 0,10062343 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04445665 0,10052886 ! transcription termination GO:0006353 13 7 0,000 0,04445665 0,10043446 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04445665 0,10034025 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04445665 0,10024621 ! anaphase GO:0051322 17 7 0,000 0,04445665 0,10015234 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04445665 0,10005866 ! axonal fasciculation GO:0007413 18 7 0,000 0,04445665 0,09996514 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04445665 0,09987181 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04445665 0,09977864 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04445665 0,09968565 ! diuresis GO:0030146 12 7 0,000 0,04445665 0,09959283 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04445665 0,09950019 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04445665 0,09940772 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04445665 0,09931542 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04445665 0,09922329 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04445665 0,09913133 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04445665 0,09903954 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04445665 0,09894792 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04445665 0,09885647 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04445665 0,09876519 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04445665 0,09867408 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04445665 0,09858314 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04445665 0,09849236 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04445665 0,09840175 ! lymph node development GO:0048535 10 7 0,000 0,04445665 0,09831131 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04445665 0,09822103 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04445665 0,09813092 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04445665 0,09804097 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04445665 0,09795119 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04445665 0,09786158 ! adult feeding behavior GO:0008343 9 7 0,000 0,04445665 0,09777212 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04445665 0,09768283 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04445665 0,09759371 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04445665 0,09750474 ! muscle adaptation GO:0043500 14 7 0,000 0,04445665 0,09741594 ! retina homeostasis GO:0001895 12 7 0,000 0,04445665 0,0973273 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04445665 0,09723882 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04445665 0,0971505 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04445665 0,09706234 ! protein prenylation GO:0018342 18 7 0,000 0,04445665 0,09697435 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04445665 0,09688651 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04445665 0,09679883 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04445665 0,0967113 ! membrane fusion GO:0006944 110 52 1,000 0,04476948 0,09730385 ! covalent chromatin modification GO:0016569 101 52 1,000 0,04476948 0,09721603 ! amino acid activation GO:0043038 92 52 1,000 0,04476948 0,09712837 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cell maturation GO:0048469 100 53 1,000 0,04633157 0,10042681 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,04633157 0,10033642 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04791349 0,10366893 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,04791349 0,10357578 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,04791349 0,10348281 ! glucose catabolic process GO:0006007 82 55 1,000 0,0495149 0,1068456 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,0495149 0,10674986 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,0495149 0,1066543 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,0495149 0,1065589 ! heart morphogenesis GO:0003007 97 55 1,000 0,0495149 0,10646367 ! RNA elongation GO:0006354 79 55 1,000 0,0495149 0,10636861 ! nuclear export GO:0051168 97 55 1,000 0,0495149 0,10627373 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05064499 0,10860236 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05064499 0,10850566 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,05064499 0,10840912 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05064499 0,10831276 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05064499 0,10821656 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05064499 0,10812054 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05064499 0,10802469 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05064499 0,10792901 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,05064499 0,1078335 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05064499 0,10773815 ! meiotic prophase I GO:0007128 13 8 0,000 0,05064499 0,10764298 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05064499 0,10754797 ! oligopeptide transport GO:0006857 15 8 0,000 0,05064499 0,10745313 ! UTP metabolic process GO:0046051 8 8 0,000 0,05064499 0,10735846 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05064499 0,10726395 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05064499 0,10716961 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05064499 0,10707544 ! succinate metabolic process GO:0006105 14 8 0,000 0,05064499 0,10698143 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05064499 0,10688759 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,05064499 0,10679391 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,05064499 0,1067004 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05064499 0,10660704 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05064499 0,10651386 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05064499 0,10642083 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05064499 0,10632797 ! reflex GO:0060004 16 8 0,000 0,05064499 0,10623527 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05064499 0,10614273 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05064499 0,10605035 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05064499 0,10595813 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05064499 0,10586607 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,05064499 0,10577418 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05064499 0,10568244 ! pigment granule organization GO:0048753 16 8 0,000 0,05064499 0,10559086 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05064499 0,10549944 ! astrocyte differentiation GO:0048708 18 8 0,000 0,05064499 0,10540818 ! histidine metabolic process GO:0006547 16 8 0,000 0,05064499 0,10531707 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05064499 0,10522612 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05064499 0,10513533 ! glycine catabolic process GO:0006546 13 8 0,000 0,05064499 0,1050447 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05064499 0,10495422 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,05064499 0,1048639 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05064499 0,10477373 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,05064499 0,10468372 ! melanin metabolic process GO:0006582 15 8 0,000 0,05064499 0,10459386 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,05064499 0,10450416 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05064499 0,10441461 ! macrophage activation GO:0042116 12 8 0,000 0,05064499 0,10432522 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05064499 0,10423597 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05064499 0,10414688 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05064499 0,10405794 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,05064499 0,10396916 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05064499 0,10388052 ! osteoblast development GO:0002076 16 8 0,000 0,05064499 0,10379204 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05064499 0,1037037 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05064499 0,10361552 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05064499 0,10352749 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,05064499 0,1034396 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05064499 0,10335187 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05064499 0,10326428 ! response to UV-B GO:0010224 16 8 0,000 0,05064499 0,10317684 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05064499 0,10308955 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05064499 0,10300241 ! intermediate filament organization GO:0045109 12 8 0,000 0,05064499 0,10291542 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05064499 0,10282857 ! cellular extravasation GO:0045123 12 8 0,000 0,05064499 0,10274187 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05064499 0,10265531 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05064499 0,1025689 ! response to antibiotic GO:0046677 11 8 0,000 0,05064499 0,10248263 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05064499 0,10239651 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05064499 0,10231054 ! DNA topological change GO:0006265 12 8 0,000 0,05064499 0,10222471 ! response to tropane GO:0014073 15 8 0,000 0,05064499 0,10213902 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05064499 0,10205348 ! melanosome transport GO:0032402 13 8 0,000 0,05064499 0,10196808 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05064499 0,10188282 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05064499 0,1017977 ! mast cell activation GO:0045576 14 8 0,000 0,05064499 0,10171273 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05064499 0,1016279 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05064499 0,10154321 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05064499 0,10145866 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05064499 0,10137425 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05064499 0,10128999 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,05064499 0,10120586 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05064499 0,10112187 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05064499 0,10103802 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05064499 0,10095431 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05064499 0,10087074 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05064499 0,10078731 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05064499 0,10070401 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05064499 0,10062085 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05064499 0,10053783 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05064499 0,10045495 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05064499 0,1003722 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05064499 0,10028959 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05064499 0,10020712 ! hormone catabolic process GO:0042447 17 8 0,000 0,05064499 0,10012478 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05064499 0,10004257 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05064499 0,0999605 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05064499 0,09987857 ! ATP catabolic process GO:0006200 11 8 0,000 0,05064499 0,09979677 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05064499 0,0997151 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05064499 0,09963357 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05064499 0,09955217 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05064499 0,0994709 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05064499 0,09938977 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05064499 0,09930876 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05064499 0,09922789 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05064499 0,09914715 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05064499 0,09906655 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05064499 0,09898607 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05064499 0,09890572 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05064499 0,09882551 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05064499 0,09874542 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05064499 0,09866547 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05064499 0,09858564 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05064499 0,09850594 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,05277497 0,10256589 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,05277497 0,10248311 ! maintenance of location GO:0051235 118 57 1,000 0,05277497 0,10240046 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,054433 0,10553247 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,054433 0,1054475 ! DNA catabolic process GO:0006308 86 59 1,000 0,05610929 0,10860736 ! establishment of organelle localization GO:0051656 109 59 1,000 0,05610929 0,10852005 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05679346 0,10975507 ! axon extension GO:0048675 15 9 0,000 0,05679346 0,10966699 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05679346 0,10957904 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05679346 0,10949124 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05679346 0,10940358 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05679346 0,10931605 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05679346 0,10922867 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05679346 0,10914143 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05679346 0,10905432 ! phosphate transport GO:0006817 19 9 0,000 0,05679346 0,10896736 ! reproductive behavior GO:0019098 19 9 0,000 0,05679346 0,10888053 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05679346 0,10879384 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05679346 0,10870729 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05679346 0,10862088 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05679346 0,1085346 ! GTP metabolic process GO:0046039 9 9 0,000 0,05679346 0,10844847 ! RNA methylation GO:0001510 15 9 0,000 0,05679346 0,10836246 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05679346 0,1082766 ! artery development GO:0060840 24 9 0,000 0,05679346 0,10819087 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05679346 0,10810527 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05679346 0,10801982 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05679346 0,10793449 ! chemosensory behavior GO:0007635 20 9 0,000 0,05679346 0,1078493 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05679346 0,10776425 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05679346 0,10767933 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05679346 0,10759454 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05679346 0,10750989 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05679346 0,10742537 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05679346 0,10734098 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05679346 0,10725672 ! protein targeting to ER GO:0045047 22 9 0,000 0,05679346 0,1071726 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05679346 0,10708861 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05679346 0,10700475 ! T cell selection GO:0045058 23 9 0,000 0,05679346 0,10692102 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05679346 0,10683742 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05679346 0,10675396 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05679346 0,10667062 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05679346 0,10658742 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05679346 0,10650434 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05679346 0,10642139 ! mannose metabolic process GO:0006013 13 9 0,000 0,05679346 0,10633857 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05679346 0,10625588 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05679346 0,10617332 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05679346 0,10609089 ! receptor clustering GO:0043113 18 9 0,000 0,05679346 0,10600859 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05679346 0,10592641 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05679346 0,10584436 ! ruffle organization GO:0031529 15 9 0,000 0,05679346 0,10576244 ! retinol metabolic process GO:0042572 18 9 0,000 0,05679346 0,10568064 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05679346 0,10559897 ! behavioral fear response GO:0001662 22 9 0,000 0,05679346 0,10551743 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05679346 0,10543601 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05679346 0,10535472 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05679346 0,10527355 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05679346 0,10519251 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05679346 0,10511159 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05679346 0,1050308 ! segment specification GO:0007379 13 9 0,000 0,05679346 0,10495013 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05679346 0,10486958 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05679346 0,10478916 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05679346 0,10470886 ! response to amine stimulus GO:0014075 13 9 0,000 0,05679346 0,10462869 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05679346 0,10454864 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05679346 0,10446871 ! erythrocyte development GO:0048821 15 9 0,000 0,05679346 0,1043889 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05679346 0,10430921 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05679346 0,10422965 ! renal water homeostasis GO:0003091 14 9 0,000 0,05679346 0,1041502 ! postreplication repair GO:0006301 22 9 0,000 0,05679346 0,10407088 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05679346 0,10399168 ! icosanoid secretion GO:0032309 15 9 0,000 0,05679346 0,1039126 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05679346 0,10383364 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05679346 0,1037548 ! regulation of cell division GO:0051302 15 9 0,000 0,05679346 0,10367607 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05679346 0,10359747 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05679346 0,10351899 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05679346 0,10344063 ! sterol catabolic process GO:0016127 11 9 0,000 0,05679346 0,10336238 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05679346 0,10328425 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05679346 0,10320624 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05679346 0,10312835 GO:0002820|negative regulation of adaptive immune response, ! musculoskeletal movement GO:0050881 14 9 0,000 0,05679346 0,10305058 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05679346 0,10297292 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05679346 0,10289538 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05679346 0,10281796 ! purine base metabolic process GO:0006144 21 9 0,000 0,05679346 0,10274065 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05679346 0,10266346 ! pigment granule transport GO:0051904 17 9 0,000 0,05679346 0,10258639 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05679346 0,10250943 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05679346 0,10243258 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05679346 0,10235586 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05679346 0,10227924 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05679346 0,10220274 ! mitochondrion localization GO:0051646 15 9 0,000 0,05679346 0,10212636 ! camera-type eye development GO:0043010 116 60 1,000 0,05780353 0,10386504 ! mesoderm development GO:0007498 119 61 1,000 0,05951542 0,10686127 ! gonad development GO:0008406 98 62 1,000 0,06124467 0,10988417 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06290231 0,11277419 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06290231 0,11269022 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06290231 0,11260637 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06290231 0,11252265 ! synapsis GO:0007129 13 10 0,000 0,06290231 0,11243905 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06290231 0,11235558 ! N-glycan processing GO:0006491 20 10 0,000 0,06290231 0,11227223 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06290231 0,112189 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06290231 0,1121059 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06290231 0,11202292 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06290231 0,11194006 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06290231 0,11185733 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06290231 0,11177471 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06290231 0,11169222 ! androgen metabolic process GO:0008209 17 10 0,000 0,06290231 0,11160985 ! phospholipid efflux GO:0033700 16 10 0,000 0,06290231 0,11152761 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06290231 0,11144548 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06290231 0,11136347 ! pathogenesis GO:0009405 13 10 0,000 0,06290231 0,11128159 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06290231 0,11119982 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06290231 0,11111818 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06290231 0,11103666 ! endoderm development GO:0007492 16 10 0,000 0,06290231 0,11095525 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06290231 0,11087396 ! arginine catabolic process GO:0006527 13 10 0,000 0,06290231 0,1107928 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06290231 0,11071175 ! proline metabolic process GO:0006560 13 10 0,000 0,06290231 0,11063082 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06290231 0,11055001 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06290231 0,11046931 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06290231 0,11038874 ! V(D)J recombination GO:0033151 28 10 0,000 0,06290231 0,11030828 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06290231 0,11022794 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06290231 0,11014772 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06290231 0,11006761 ! B cell proliferation GO:0042100 18 10 0,000 0,06290231 0,10998762 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06290231 0,10990774 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06290231 0,10982798 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06290231 0,10974834 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06290231 0,10966881 ! epithelial cell development GO:0002064 20 10 0,000 0,06290231 0,1095894 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06290231 0,1095101 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06290231 0,10943092 ! macroautophagy GO:0016236 17 10 0,000 0,06290231 0,10935185 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06290231 0,1092729 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06290231 0,10919406 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06290231 0,10911533 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06290231 0,10903672 ! brain morphogenesis GO:0048854 23 10 0,000 0,06290231 0,10895822 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06290231 0,10887983 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06290231 0,10880155 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06290231 0,10872339 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,06290231 0,10864534 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06290231 0,1085674 ! response to dsRNA GO:0043331 20 10 0,000 0,06290231 0,10848958 ! DNA ligation GO:0006266 19 10 0,000 0,06290231 0,10841186 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06290231 0,10833426 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06290231 0,10825677 ! melanosome localization GO:0032400 16 10 0,000 0,06290231 0,10817939 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06290231 0,10810212 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06290231 0,10802495 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06290231 0,1079479 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06290231 0,10787096 ! mRNA cleavage GO:0006379 17 10 0,000 0,06290231 0,10779413 ! protein sumoylation GO:0016925 15 10 0,000 0,06290231 0,10771741 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06290231 0,1076408 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06290231 0,10756429 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06290231 0,1074879 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06290231 0,10741161 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06290231 0,10733543 ! salivary gland development GO:0007431 27 10 0,000 0,06290231 0,10725936 ! prophase GO:0051324 15 10 0,000 0,06290231 0,1071834 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06290231 0,10710755 ! apical protein localization GO:0045176 15 10 0,000 0,06290231 0,1070318 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06290231 0,10695616 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06290231 0,10688062 ! midbrain development GO:0030901 13 10 0,000 0,06290231 0,10680519 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06290231 0,10672987 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06290231 0,10665466 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06290231 0,10657955 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06290231 0,10650455 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06290231 0,10642965 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06290231 0,10635486 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06290231 0,10628017 ! detection of calcium ion GO:0005513 23 10 0,000 0,06290231 0,10620559 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06290231 0,10613111 ! blastocyst formation GO:0001825 17 10 0,000 0,06290231 0,10605674 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06290231 0,10598247 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06290231 0,1059083 ! activation of innate immune response GO:0002218 12 10 0,000 0,06290231 0,10583424 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06290231 0,10576028 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06290231 0,10568643 ! response to nicotine GO:0035094 20 10 0,000 0,06290231 0,10561267 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06290231 0,10553902 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06290231 0,10546548 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,06299098 0,10554059 ! single fertilization GO:0007338 75 64 1,000 0,06475406 0,10841911 ! germ cell development GO:0007281 118 65 1,000 0,06653362 0,11132121 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,06653362 0,11124385 ! actin filament organization GO:0007015 148 66 1,000 0,06832939 0,11416702 ! secondary metabolic process GO:0019748 116 66 1,000 0,06832939 0,11408779 ! developmental maturation GO:0021700 116 66 1,000 0,06832939 0,11400867 ! cell projection assembly GO:0030031 120 66 1,000 0,06832939 0,11392966 ! respiratory burst GO:0045730 17 11 0,000 0,0689718 0,11492115 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0689718 0,11484162 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0689718 0,1147622 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0689718 0,11468289 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0689718 0,11460369 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0689718 0,1145246 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0689718 0,11444562 ! response to pain GO:0048265 24 11 0,000 0,0689718 0,11436675 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0689718 0,11428798 ! T cell proliferation GO:0042098 26 11 0,000 0,0689718 0,11420932 ! bone resorption GO:0045453 16 11 0,000 0,0689718 0,11413078 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0689718 0,11405233 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0689718 0,113974 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0689718 0,11389578 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0689718 0,11381766 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0689718 0,11373965 ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0689718 0,11366174 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0689718 0,11358395 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0689718 0,11350626 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0689718 0,11342867 ! UV protection GO:0009650 19 11 0,000 0,0689718 0,11335119 ! adult heart development GO:0007512 14 11 0,000 0,0689718 0,11327382 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0689718 0,11319655 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0689718 0,11311939 ! temperature homeostasis GO:0001659 17 11 0,000 0,0689718 0,11304233 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0689718 0,11296538 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0689718 0,11288854 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0689718 0,11281179 ! regulation of organ growth GO:0046620 13 11 0,000 0,0689718 0,11273515 ! pigment granule localization GO:0051875 20 11 0,000 0,0689718 0,11265862 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0689718 0,11258219 ! vasoconstriction GO:0042310 18 11 0,000 0,0689718 0,11250586 ! embryonic axis specification GO:0000578 18 11 0,000 0,0689718 0,11242964 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0689718 0,11235352 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0689718 0,1122775 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0689718 0,11220159 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0689718 0,11212578 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0689718 0,11205007 ! zymogen activation GO:0031638 15 11 0,000 0,0689718 0,11197446 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0689718 0,11189895 ! nucleosome positioning GO:0016584 15 11 0,000 0,0689718 0,11182355 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0689718 0,11174825 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0689718 0,11167305 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0689718 0,11159795 ! acid secretion GO:0046717 18 11 0,000 0,0689718 0,11152295 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0689718 0,11144805 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0689718 0,11137325 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0689718 0,11129856 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0689718 0,11122396 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0689718 0,11114946 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,0689718 0,11107507 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0689718 0,11100077 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0689718 0,11092657 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0689718 0,11085247 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0689718 0,11077847 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0689718 0,11070457 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0689718 0,11063076 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0689718 0,11055706 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0689718 0,11048345 ! defense response to fungus GO:0050832 13 11 0,000 0,0689718 0,11040994 ! lysogeny GO:0030069 21 11 0,000 0,0689718 0,11033653 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0689718 0,11026322 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0689718 0,11019 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0689718 0,11011689 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0689718 0,11004386 ! regulation of embryonic development GO:0045995 27 11 0,000 0,0689718 0,10997094 ! nucleus localization GO:0051647 19 11 0,000 0,0689718 0,10989811 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0689718 0,10982538 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,07014107 0,11161336 ! activation of MAPK activity GO:0000187 115 67 1,000 0,07014107 0,11153959 ! chromosome segregation GO:0007059 113 67 1,000 0,07014107 0,11146592 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,07014107 0,11139235 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,07014107 0,11131887 ! hexose catabolic process GO:0019320 104 67 1,000 0,07014107 0,11124549 ! adaptive immune response GO:0002250 119 67 1,000 0,07014107 0,1111722 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 0,07196838 0,11399337 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,07196838 0,11391837 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07500217 0,11864249 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07500217 0,11856454 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07500217 0,11848669 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07500217 0,11840894 ! virus-host interaction GO:0019048 29 12 0,000 0,07500217 0,1183313 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07500217 0,11825376 ! mating GO:0007618 17 12 0,000 0,07500217 0,11817631 ! protein complex disassembly GO:0043241 27 12 0,000 0,07500217 0,11809897 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07500217 0,11802173 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07500217 0,1179446 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07500217 0,11786756 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07500217 0,11779062 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07500217 0,11771378 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07500217 0,11763705 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07500217 0,11756041 ! drug transport GO:0015893 16 12 0,000 0,07500217 0,11748387 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07500217 0,11740744 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07500217 0,1173311 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07500217 0,11725486 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07500217 0,11717872 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07500217 0,11710268 ! forebrain cell migration GO:0021885 21 12 0,000 0,07500217 0,11702674 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07500217 0,1169509 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07500217 0,11687515 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07500217 0,1167995 ! fear response GO:0042596 26 12 0,000 0,07500217 0,11672395 ! monoamine transport GO:0015844 18 12 0,000 0,07500217 0,1166485 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07500217 0,11657315 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07500217 0,11649789 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07500217 0,11642273 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07500217 0,11634767 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07500217 0,1162727 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07500217 0,11619783 ! protein homotetramerization GO:0051289 21 12 0,000 0,07500217 0,11612306 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07500217 0,11604838 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07500217 0,1159738 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07500217 0,11589931 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07500217 0,11582492 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07500217 0,11575063 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07500217 0,11567643 ! fucose catabolic process GO:0019317 22 12 0,000 0,07500217 0,11560233 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07500217 0,11552832 ! histone methylation GO:0016571 26 12 0,000 0,07500217 0,1154544 ! gland morphogenesis GO:0022612 29 12 0,000 0,07500217 0,11538058 ! T cell homeostasis GO:0043029 25 12 0,000 0,07500217 0,11530686 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07500217 0,11523323 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07500217 0,11515969 ! spleen development GO:0048536 22 12 0,000 0,07500217 0,11508624 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07500217 0,11501289 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07500217 0,11493964 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07500217 0,11486647 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07500217 0,1147934 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07500217 0,11472043 ! response to cold GO:0009409 17 12 0,000 0,07500217 0,11464754 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07500217 0,11457475 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07500217 0,11450205 ! reproductive structure development GO:0048608 113 71 1,000 0,07754141 0,11830351 ! B cell activation GO:0042113 160 71 1,000 0,07754141 0,11822854 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,07754141 0,11815367 ! carbohydrate transport GO:0008643 110 72 1,000 0,07942855 0,12095259 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08099369 0,12325795 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,08099369 0,12318004 ! peroxisomal transport GO:0043574 24 13 0,000 0,08099369 0,12310222 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,08099369 0,12302451 ! lipid localization GO:0010876 28 13 0,000 0,08099369 0,12294689 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,08099369 0,12286937 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,08099369 0,12279195 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,08099369 0,12271462 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,08099369 0,12263739 ! endocrine pancreas development GO:0031018 22 13 0,000 0,08099369 0,12256026 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,08099369 0,12248323 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,08099369 0,12240629 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,08099369 0,12232945 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,08099369 0,12225271 ! methionine metabolic process GO:0006555 27 13 0,000 0,08099369 0,12217606 ! plasma membrane organization GO:0007009 24 13 0,000 0,08099369 0,12209951 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,08099369 0,12202305 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,08099369 0,12194669 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,08099369 0,12187043 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,08099369 0,12179426 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,08099369 0,12171819 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,08099369 0,12164221 ! exocrine system development GO:0035272 32 13 0,000 0,08099369 0,12156632 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,08099369 0,12149054 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,08099369 0,12141484 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,08099369 0,12133924 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,08099369 0,12126373 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,08099369 0,12118832 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,08099369 0,121113 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,08099369 0,12103778 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,08099369 0,12096264 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08099369 0,1208876 ! ribosome assembly GO:0042255 17 13 0,000 0,08099369 0,12081266 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,08099369 0,12073781 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,08099369 0,12066305 ! chromatin silencing GO:0006342 26 13 0,000 0,08099369 0,12058838 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,08099369 0,1205138 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08099369 0,12043932 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08099369 0,12036493 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,08099369 0,12029063 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,08099369 0,12021642 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08099369 0,1201423 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,08099369 0,12006828 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,08099369 0,11999435 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,08099369 0,1199205 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,08099369 0,11984675 ! insulin secretion GO:0030073 23 13 0,000 0,08099369 0,11977309 ! actin filament polymerization GO:0030041 24 13 0,000 0,08099369 0,11969952 ! acrosome reaction GO:0007340 18 13 0,000 0,08099369 0,11962604 ! learning or memory GO:0007611 147 73 1,000 0,08132997 0,12004903 ! regulation of blood pressure GO:0008217 125 73 1,000 0,08132997 0,11997542 ! fertilization GO:0009566 90 73 1,000 0,08132997 0,11990191 ! eye development GO:0001654 143 74 1,000 0,08324542 0,12265063 ! organelle localization GO:0051640 136 74 1,000 0,08324542 0,12257557 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,08517463 0,12533955 ! rRNA transcription GO:0009303 25 14 0,000 0,08694659 0,12786889 ! lactation GO:0007595 26 14 0,000 0,08694659 0,12779078 ! reproductive cellular process GO:0048610 20 14 0,000 0,08694659 0,12771276 ! tRNA modification GO:0006400 20 14 0,000 0,08694659 0,12763484 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08694659 0,12755702 ! water transport GO:0006833 21 14 0,000 0,08694659 0,12747928 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08694659 0,12740165 ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08694659 0,12732411 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08694659 0,12724666 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08694659 0,1271693 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08694659 0,12709204 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08694659 0,12701488 ! palate development GO:0060021 31 14 0,000 0,08694659 0,12693781 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08694659 0,12686083 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08694659 0,12678394 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08694659 0,12670715 ! arginine metabolic process GO:0006525 17 14 0,000 0,08694659 0,12663045 ! regulation of heart rate GO:0002027 24 14 0,000 0,08694659 0,12655385 ! organic alcohol transport GO:0015850 29 14 0,000 0,08694659 0,12647733 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,08694659 0,12640091 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08694659 0,12632458 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08694659 0,12624834 ! L-amino acid transport GO:0015807 30 14 0,000 0,08694659 0,1261722 ! bone mineralization GO:0030282 17 14 0,000 0,08694659 0,12609615 ! stem cell development GO:0048864 43 14 0,000 0,08694659 0,12602018 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,08694659 0,12594431 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08694659 0,12586854 ! cerebellum development GO:0021549 21 14 0,000 0,08694659 0,12579285 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08694659 0,12571725 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08694659 0,12564175 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08694659 0,12556633 ! cofactor transport GO:0051181 26 14 0,000 0,08694659 0,12549101 ! NADP metabolic process GO:0006739 24 14 0,000 0,08694659 0,12541577 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08694659 0,12534063 ! intestinal absorption GO:0050892 25 14 0,000 0,08694659 0,12526557 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08694659 0,12519061 ! oxygen transport GO:0015671 21 14 0,000 0,08694659 0,12511573 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08694659 0,12504095 ! male genitalia development GO:0030539 24 14 0,000 0,08694659 0,12496625 ! regulation of axon extension GO:0030516 37 14 0,000 0,08694659 0,12489165 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08694659 0,12481713 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,08711735 0,12498769 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,08711735 0,1249132 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,08907333 0,12764171 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,09104231 0,1303856 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,09104231 0,13030803 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,09286113 0,13283228 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09286113 0,13275335 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,09286113 0,13267452 ! superoxide anion generation GO:0042554 20 15 0,000 0,09286113 0,13259578 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,09286113 0,13251714 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,09286113 0,13243858 ! copper ion transport GO:0006825 20 15 0,000 0,09286113 0,13236012 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,09286113 0,13228176 ! sulfate transport GO:0008272 23 15 0,000 0,09286113 0,13220349 ! response to cAMP GO:0051591 22 15 0,000 0,09286113 0,1321253 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,09286113 0,13204722 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,09286113 0,13196922 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,09286113 0,13189132 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,09286113 0,1318135 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,09286113 0,13173578 ! response to hexose stimulus GO:0009746 22 15 0,000 0,09286113 0,13165816 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,09286113 0,13158062 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,09286113 0,13150317 ! pituitary gland development GO:0021983 29 15 0,000 0,09286113 0,13142582 ! vesicle coating GO:0006901 33 15 0,000 0,09286113 0,13134855 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,09286113 0,13127138 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,09286113 0,1311943 ! regulation of exocytosis GO:0017157 22 15 0,000 0,09286113 0,13111731 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,09286113 0,1310404 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,09286113 0,13096359 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,09286113 0,13088687 ! regulation of vasodilation GO:0042312 26 15 0,000 0,09286113 0,13081024 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,09286113 0,1307337 ! histone deacetylation GO:0016575 20 15 0,000 0,09286113 0,13065725 ! mRNA splice site selection GO:0006376 38 15 0,000 0,09286113 0,13058088 ! tissue regeneration GO:0042246 26 15 0,000 0,09286113 0,13050461 ! water homeostasis GO:0030104 27 15 0,000 0,09286113 0,13042842 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09286113 0,13035233 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,09286113 0,13027632 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,09286113 0,1302004 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,09286113 0,13012457 ! dopamine metabolic process GO:0042417 35 15 0,000 0,09286113 0,13004883 ! heme biosynthetic process GO:0006783 29 15 0,000 0,09286113 0,12997318 ! cell killing GO:0001906 29 15 0,000 0,09286113 0,12989761 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,09286113 0,12982213 ! detection of bacterium GO:0016045 18 15 0,000 0,09286113 0,12974674 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,09286113 0,12967144 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,09286113 0,12959622 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,09286113 0,1295211 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,09302405 0,12967315 ! muscle cell differentiation GO:0042692 159 80 1,000 0,0950183 0,13237639 ! T cell activation GO:0042110 168 81 1,000 0,09702481 0,13509358 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,09702481 0,13501544 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,09702481 0,1349374 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09873756 0,13724007 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09873756 0,13716083 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09873756 0,13708169 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09873756 0,13700263 ! bone remodeling GO:0046849 27 16 0,000 0,09873756 0,13692367 ! filopodium assembly GO:0046847 32 16 0,000 0,09873756 0,13684479 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09873756 0,13676601 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09873756 0,13668732 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09873756 0,13660872 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09873756 0,13653021 ! startle response GO:0001964 28 16 0,000 0,09873756 0,13645179 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09873756 0,13637346 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09873756 0,13629522 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09873756 0,13621707 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09873756 0,136139 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09873756 0,13606103 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09873756 0,13598315 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09873756 0,13590536 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09873756 0,13582765 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09873756 0,13575004 ! response to osmotic stress GO:0006970 25 16 0,000 0,09873756 0,13567251 ! lysosomal transport GO:0007041 26 16 0,000 0,09873756 0,13559507 ! fructose metabolic process GO:0006000 25 16 0,000 0,09873756 0,13551772 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09873756 0,13544046 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09873756 0,13536328 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09873756 0,1352862 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09873756 0,1352092 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09873756 0,13513229 ! axon cargo transport GO:0008088 43 16 0,000 0,09873756 0,13505547 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09873756 0,13497873 ! DNA replication initiation GO:0006270 27 16 0,000 0,09873756 0,13490208 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09873756 0,13482552 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09873756 0,13474904 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09873756 0,13467266 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09873756 0,13459635 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09873756 0,13452014 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09873756 0,13444401 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09873756 0,13436797 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09873756 0,13429201 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09873756 0,13421614 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09873756 0,13414035 ! defense response to virus GO:0051607 37 16 0,000 0,09873756 0,13406465 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,10457611 0,14191208 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,10457611 0,14183208 ! metencephalon development GO:0022037 30 17 0,000 0,10457611 0,14175218 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10457611 0,14167236 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10457611 0,14159264 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10457611 0,141513 ! signal complex assembly GO:0007172 41 17 0,000 0,10457611 0,14143345 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10457611 0,141354 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10457611 0,14127463 ! glial cell development GO:0021782 27 17 0,000 0,10457611 0,14119535 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10457611 0,14111616 ! adult walking behavior GO:0007628 33 17 0,000 0,10457611 0,14103706 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10457611 0,14095805 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,10457611 0,14087912 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,10457611 0,14080029 ! myoblast differentiation GO:0045445 45 17 0,000 0,10457611 0,14072154 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,10457611 0,14064288 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10457611 0,14056431 ! glycine metabolic process GO:0006544 28 17 0,000 0,10457611 0,14048583 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,10457611 0,14040743 ! NAD metabolic process GO:0019674 29 17 0,000 0,10457611 0,14032912 ! membrane budding GO:0006900 37 17 0,000 0,10457611 0,1402509 ! DNA integration GO:0015074 29 17 0,000 0,10457611 0,14017277 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,10457611 0,14009472 ! regulation of protein binding GO:0043393 33 17 0,000 0,10457611 0,14001676 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10457611 0,13993888 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10457611 0,1398611 ! genitalia development GO:0048806 30 17 0,000 0,10457611 0,1397834 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10457611 0,13970578 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,10457611 0,13962825 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10457611 0,13955081 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,10457611 0,13947346 ! steroid catabolic process GO:0006706 31 17 0,000 0,10457611 0,13939618 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,10457611 0,139319 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,10457611 0,1392419 ! gas transport GO:0015669 25 17 0,000 0,10457611 0,13916489 ! organic cation transport GO:0015695 31 17 0,000 0,10457611 0,13908796 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,10457611 0,13901111 ! microspike assembly GO:0030035 36 17 0,000 0,10457611 0,13893435 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,10457611 0,13885768 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,10516878 0,13956762 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,10516878 0,13949068 GO:0002696|positive regulation of leukocyte activation, ! alcohol catabolic process GO:0046164 130 86 1,000 0,10723308 0,1421503 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,11037703 0,1462374 ! neuron maturation GO:0042551 42 18 0,000 0,11037703 0,14615692 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,11037703 0,14607653 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,11037703 0,14599622 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,11037703 0,145916 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,11037703 0,14583587 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,11037703 0,14575583 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,11037703 0,14567588 ! patterning of blood vessels GO:0001569 39 18 0,000 0,11037703 0,14559601 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,11037703 0,14551623 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,11037703 0,14543654 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,11037703 0,14535694 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11037703 0,14527742 ! response to fungus GO:0009620 21 18 0,000 0,11037703 0,14519799 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,11037703 0,14511865 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,11037703 0,14503939 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,11037703 0,14496022 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,11037703 0,14488114 ! vitamin transport GO:0051180 27 18 0,000 0,11037703 0,14480214 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,11037703 0,14472323 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,11037703 0,1446444 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,11037703 0,14456566 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,11037703 0,14448701 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,11037703 0,14440844 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,11037703 0,14432996 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,11349026 0,14832024 ! sex differentiation GO:0007548 145 90 1,000 0,11559667 0,15099108 ! positive regulation of translation GO:0045727 30 19 0,000 0,11614056 0,1516192 ! negative regulation of defense response GO:0031348 25 19 0,000 0,11614056 0,15153697 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,11614056 0,15145484 ! skin development GO:0043588 36 19 0,000 0,11614056 0,15137279 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,11614056 0,15129084 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11614056 0,15120897 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,11614056 0,15112719 ! bile acid metabolic process GO:0008206 29 19 0,000 0,11614056 0,1510455 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,11614056 0,1509639 ! cerebral cortex development GO:0021987 36 19 0,000 0,11614056 0,15088238 ! pigmentation during development GO:0048066 41 19 0,000 0,11614056 0,15080096 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,11614056 0,15071962 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,11614056 0,15063837 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,11614056 0,15055721 ! peptide cross-linking GO:0018149 37 19 0,000 0,11614056 0,15047613 ! protein export from nucleus GO:0006611 36 19 0,000 0,11614056 0,15039514 ! heart process GO:0003015 30 19 0,000 0,11614056 0,15031424 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,11614056 0,15023343 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,11614056 0,1501527 ! visual learning GO:0008542 36 19 0,000 0,11614056 0,15007206 ! cellular pigmentation GO:0033059 36 19 0,000 0,11614056 0,14999151 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,11614056 0,14991104 ! cell-cell junction organization GO:0045216 35 19 0,000 0,11614056 0,14983066 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,11614056 0,14975036 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,11614056 0,14967015 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,11614056 0,14959003 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,11614056 0,14950999 ! cilium assembly GO:0042384 37 19 0,000 0,11614056 0,14943004 ! peptide hormone secretion GO:0030072 31 19 0,000 0,11614056 0,14935017 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,12186694 0,15663026 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,12186694 0,15654664 ! positive regulation of ossification GO:0045778 47 20 0,000 0,12186694 0,1564631 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,12186694 0,15637965 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,12186694 0,15629629 ! cAMP metabolic process GO:0046058 36 20 0,000 0,12186694 0,15621302 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,12186694 0,15612984 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,12186694 0,15604675 ! response to alkaloid GO:0043279 38 20 0,000 0,12186694 0,15596375 ! retinoid metabolic process GO:0001523 32 20 0,000 0,12186694 0,15588083 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,12186694 0,15579801 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,12186694 0,15571527 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,12186694 0,15563262 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,12186694 0,15555005 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,12186694 0,15546758 ! body fluid secretion GO:0007589 31 20 0,000 0,12186694 0,15538519 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,12186694 0,15530289 ! peptide secretion GO:0002790 35 20 0,000 0,12186694 0,15522067 ! stem cell differentiation GO:0048863 53 20 0,000 0,12186694 0,15513854 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,12186694 0,1550565 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,12186694 0,15497455 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,12186694 0,15489268 ! sensory perception of pain GO:0019233 30 20 0,000 0,12186694 0,1548109 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,12186694 0,15472921 ! diencephalon development GO:0021536 34 20 0,000 0,12186694 0,1546476 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,12186694 0,15456608 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,12186694 0,15448464 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,12186694 0,15440329 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,12186694 0,15432203 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,12186694 0,15424085 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,12186694 0,15415975 ! regulation of glucose import GO:0046324 29 20 0,000 0,12186694 0,15407874 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,12186694 0,15399782 ! actin filament-based movement GO:0030048 43 20 0,000 0,12186694 0,15391698 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,12186694 0,15383623 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,12186694 0,15375556 ! negative regulation of translation GO:0017148 29 20 0,000 0,12186694 0,15367497 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,12186694 0,15359447 ! regulation of membrane potential GO:0042391 164 93 1,000 0,12197489 0,15365004 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,12197489 0,15356964 ! female pregnancy GO:0007565 164 94 1,000 0,12411992 0,15618856 ! transcription initiation GO:0006352 153 94 1,000 0,12411992 0,15610691 ! regulation of cell killing GO:0031341 42 21 0,000 0,1275564 0,1603452 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,1275564 0,16026147 ! hormone secretion GO:0046879 38 21 0,000 0,1275564 0,16017782 ! glycerol metabolic process GO:0006071 34 21 0,000 0,1275564 0,16009427 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,1275564 0,1600108 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,1275564 0,15992742 ! ovarian follicle development GO:0001541 35 21 0,000 0,1275564 0,15984412 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,1275564 0,15976091 ! smooth muscle contraction GO:0006939 46 21 0,000 0,1275564 0,15967779 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,1275564 0,15959475 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,1275564 0,1595118 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,1275564 0,15942894 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,1275564 0,15934616 ! cytolysis GO:0019835 24 21 0,000 0,1275564 0,15926347 ! vasodilation GO:0042311 39 21 0,000 0,1275564 0,15918087 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,1275564 0,15909835 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,1275564 0,15901591 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,1275564 0,15893356 ! collagen fibril organization GO:0030199 59 21 0,000 0,1275564 0,1588513 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,1275564 0,15876912 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,1275564 0,15868703 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,1275564 0,15860502 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,1275564 0,15852309 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,1275564 0,15844125 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,1275564 0,1583595 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,1275564 0,15827783 ! collagen catabolic process GO:0030574 28 21 0,000 0,1275564 0,15819624 ! sperm-egg recognition GO:0035036 21 21 0,000 0,1275564 0,15811474 ! leukocyte differentiation GO:0002521 202 96 1,000 0,12843715 0,15912451 ! hormone metabolic process GO:0042445 157 97 1,000 0,13060895 0,16173192 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,1332092 0,16486694 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,1332092 0,16478218 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,1332092 0,1646975 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,1332092 0,16461291 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,1332092 0,16452841 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,1332092 0,16444399 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,1332092 0,16435966 ! regeneration GO:0031099 41 22 0,000 0,1332092 0,16427541 ! keratinization GO:0031424 28 22 0,000 0,1332092 0,16419126 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,1332092 0,16410719 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,1332092 0,1640232 ! sensory perception of taste GO:0050909 28 22 0,000 0,1332092 0,1639393 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,1332092 0,16385549 ! vacuolar transport GO:0007034 36 22 0,000 0,1332092 0,16377176 ! lysosome organization GO:0007040 41 22 0,000 0,1332092 0,16368812 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,1332092 0,16360456 ! fucose metabolic process GO:0006004 39 22 0,000 0,1332092 0,16352109 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,1332092 0,1634377 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,1332092 0,1633544 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,1332092 0,16327118 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,1332092 0,16318805 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,1332092 0,163105 ! sarcomere organization GO:0045214 30 22 0,000 0,1332092 0,16302204 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,1332092 0,16293916 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,1332092 0,16285637 ! protein stabilization GO:0050821 39 22 0,000 0,1332092 0,16277366 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,13882555 0,1695504 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,13882555 0,16946438 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,13882555 0,16937844 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,13882555 0,16929259 ! gluconeogenesis GO:0006094 33 23 0,000 0,13882555 0,16920683 ! viral genome replication GO:0019079 41 23 0,000 0,13882555 0,16912116 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13882555 0,16903557 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,13882555 0,16895007 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13882555 0,16886465 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13882555 0,16877932 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13882555 0,16869408 ! visual behavior GO:0007632 42 23 0,000 0,13882555 0,16860893 ! response to ethanol GO:0045471 46 23 0,000 0,13882555 0,16852386 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,13882555 0,16843887 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,13882555 0,16835397 ! peroxisome organization GO:0007031 37 23 0,000 0,13882555 0,16826916 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13882555 0,16818443 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,13882555 0,16809979 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,13882555 0,16801523 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,13882555 0,16793076 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,13882555 0,16784637 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,13882555 0,16776207 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,13882555 0,16767785 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,13882555 0,16759372 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,13882555 0,16750967 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13882555 0,16742571 ! fatty acid transport GO:0015908 44 23 0,000 0,13882555 0,16734183 ! platelet activation GO:0030168 37 23 0,000 0,13882555 0,16725803 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,13882555 0,16717432 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,13882555 0,16709069 ! hormone transport GO:0009914 40 23 0,000 0,13882555 0,16700714 ! cell-cell recognition GO:0009988 25 23 0,000 0,13882555 0,16692368 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,13882555 0,1668403 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,13882555 0,16675701 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,13882555 0,16667379 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,13882555 0,16659067 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,13882555 0,16650762 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1444057 0,17311416 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1444057 0,17302795 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,1444057 0,17294182 ! vesicle docking GO:0048278 47 24 0,000 0,1444057 0,17285578 ! vacuole organization GO:0007033 43 24 0,000 0,1444057 0,17276983 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,1444057 0,17268396 ! digestive system process GO:0022600 39 24 0,000 0,1444057 0,17259817 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,1444057 0,17251247 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,1444057 0,17242686 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,1444057 0,17234133 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,1444057 0,17225589 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1444057 0,17217053 ! membrane depolarization GO:0051899 39 24 0,000 0,1444057 0,17208525 ! pentose metabolic process GO:0019321 35 24 0,000 0,1444057 0,17200006 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,1444057 0,17191495 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,1444057 0,17182993 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1444057 0,17174499 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1444057 0,17166014 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1444057 0,17157537 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1444057 0,17149068 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1444057 0,17140608 ! regulation of amine transport GO:0051952 40 24 0,000 0,1444057 0,17132156 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,14994988 0,17781144 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14994988 0,17772385 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,14994988 0,17763634 ! phototransduction GO:0007602 33 25 0,000 0,14994988 0,17754892 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14994988 0,17746159 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,14994988 0,17737434 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14994988 0,17728718 ! receptor metabolic process GO:0043112 46 25 0,000 0,14994988 0,1772001 ! chromosome condensation GO:0030261 45 25 0,000 0,14994988 0,17711311 ! osteoblast differentiation GO:0001649 60 25 0,000 0,14994988 0,17702621 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,14994988 0,17693939 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14994988 0,17685265 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,14994988 0,176766 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,14994988 0,17667944 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14994988 0,17659296 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,14994988 0,17650656 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14994988 0,17642025 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14994988 0,17633402 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,14994988 0,17624788 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,14994988 0,17616182 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,15545831 0,18254402 ! embryonic pattern specification GO:0009880 44 26 0,000 0,15545831 0,18245498 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,15545831 0,18236602 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,15545831 0,18227714 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,15545831 0,18218836 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,15545831 0,18209966 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,15545831 0,18201105 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,15545831 0,18192252 ! molting cycle process GO:0022404 50 26 0,000 0,15545831 0,18183408 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,15545831 0,18174572 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,15545831 0,18165746 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,15545831 0,18156927 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,15545831 0,18148117 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,15545831 0,18139316 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,15545831 0,18130524 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,15545831 0,18121739 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,15545831 0,18112964 ! leukocyte proliferation GO:0070661 52 26 0,000 0,15545831 0,18104197 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,15545831 0,18095438 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,16093123 0,18723431 ! iron ion transport GO:0006826 59 27 0,000 0,16093123 0,18714381 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,16093123 0,1870534 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,16093123 0,18696308 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,16093123 0,18687285 ! fat cell differentiation GO:0045444 50 27 0,000 0,16093123 0,1867827 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,16093123 0,18669265 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,16093123 0,18660267 ! autophagy GO:0006914 41 27 0,000 0,16093123 0,18651279 ! male gonad development GO:0008584 44 27 0,000 0,16093123 0,18642299 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,16093123 0,18633328 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,16093123 0,18624365 ! glutathione metabolic process GO:0006749 39 27 0,000 0,16093123 0,18615411 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,16093123 0,18606465 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,16093123 0,18597529 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,16636887 0,19216682 ! circadian rhythm GO:0007623 50 28 0,000 0,16636887 0,19207461 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,16636887 0,19198249 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,16636887 0,19189046 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,16636887 0,19179851 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,16636887 0,19170665 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,16636887 0,19161488 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,16636887 0,1915232 ! lipid oxidation GO:0034440 43 28 0,000 0,16636887 0,19143161 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,16636887 0,1913401 ! translational initiation GO:0006413 65 29 0,000 0,17177144 0,19745919 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,17177144 0,19736489 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,17177144 0,19727069 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,17177144 0,19717657 ! catechol metabolic process GO:0009712 54 29 0,000 0,17177144 0,19708254 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,17177144 0,1969886 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,17177144 0,19689475 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,17177144 0,19680099 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,17177144 0,19670732 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,17177144 0,19661374 ! cell fate determination GO:0001709 60 29 0,000 0,17177144 0,19652025 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,17177144 0,19642685 ! detection of light stimulus GO:0009583 38 29 0,000 0,17177144 0,19633353 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,17177144 0,19624031 ! regulation of coagulation GO:0050818 46 29 0,000 0,17177144 0,19614717 ! phenol metabolic process GO:0018958 55 30 0,000 0,17713918 0,20218068 ! zinc ion transport GO:0006829 45 30 0,000 0,17713918 0,20208481 ! membrane docking GO:0022406 61 30 0,000 0,17713918 0,20198904 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,17713918 0,20189335 ! regulation of innate immune response GO:0045088 51 30 0,000 0,17713918 0,20179776 ! acute-phase response GO:0006953 49 30 0,000 0,17713918 0,20170226 ! myofibril assembly GO:0030239 47 30 0,000 0,17713918 0,20160685 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,17713918 0,20151152 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,17713918 0,20141629 ! phospholipid transport GO:0015914 51 30 0,000 0,17713918 0,20132115 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,17713918 0,2012261 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,17713918 0,20113113 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,17713918 0,20103626 ! response to heat GO:0009408 50 30 0,000 0,17713918 0,20094148 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,18247231 0,20689368 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,18247231 0,20679622 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,18247231 0,20669886 GO:0009799|determination of symmetry, ! cholesterol homeostasis GO:0042632 53 31 0,000 0,18247231 0,20660159 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,18247231 0,20650441 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,18247231 0,20640733 ! ovulation cycle process GO:0022602 49 31 0,000 0,18247231 0,20631033 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,18247231 0,20621342 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,18247231 0,20611661 ! peptide transport GO:0015833 55 31 0,000 0,18247231 0,20601989 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,18247231 0,20592326 ! mesoderm formation GO:0001707 69 31 0,000 0,18247231 0,20582671 ! natural killer cell activation GO:0030101 45 31 0,000 0,18247231 0,20573026 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,18247231 0,2056339 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,18247231 0,20553763 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,18247231 0,20544145 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,18247231 0,20534536 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,18777105 0,21120951 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,18777105 0,21111082 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,18777105 0,21101221 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,18777105 0,2109137 ! cholesterol transport GO:0030301 56 32 0,000 0,18777105 0,21081528 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,18777105 0,21071695 ! spliceosome assembly GO:0000245 67 32 0,000 0,18777105 0,21061872 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,18777105 0,21052057 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,18777105 0,21042252 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,18777105 0,21032456 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,18777105 0,21022669 ! muscle cell development GO:0055001 49 32 0,000 0,18777105 0,21012891 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,18777105 0,21003122 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,18777105 0,20993362 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,18777105 0,20983611 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,18777105 0,2097387 ! ovulation cycle GO:0042698 51 32 0,000 0,18777105 0,20964137 ! BMP signaling pathway GO:0030509 64 32 0,000 0,18777105 0,20954413 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,18777105 0,20944699 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,18777105 0,20934993 ! gene silencing GO:0016458 65 32 0,000 0,18777105 0,20925296 ! post-embryonic development GO:0009791 69 33 0,000 0,19303562 0,21502024 ! protein targeting to membrane GO:0006612 68 33 0,000 0,19303562 0,21492074 ! ceramide metabolic process GO:0006672 64 33 0,000 0,19303562 0,21482133 ! formation of primary germ layer GO:0001704 72 33 0,000 0,19303562 0,21472201 ! sterol transport GO:0015918 57 33 0,000 0,19303562 0,21462279 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,19303562 0,21452365 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,19303562 0,21442461 ! adult locomotory behavior GO:0008344 59 33 0,000 0,19303562 0,21432566 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,19303562 0,2142268 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,19826625 0,21993019 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,19826625 0,21982884 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,19826625 0,21972759 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,19826625 0,21962642 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,19826625 0,21952535 ! spermatid development GO:0007286 63 34 0,000 0,19826625 0,21942437 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,19826625 0,21932349 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,19826625 0,2192227 ! negative regulation of secretion GO:0051048 63 35 0,000 0,20346314 0,22486555 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,20346314 0,22476231 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,20346314 0,22465916 GO:0006639|acylglycerol metabolic process, ! vesicle localization GO:0051648 64 35 0,000 0,20346314 0,2245561 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,20862651 0,23014919 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,20862651 0,23004372 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,20862651 0,22993834 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,20862651 0,22983305 ! regulation of proteolysis GO:0030162 72 36 0,000 0,20862651 0,22972787 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,20862651 0,22962278 ! aerobic respiration GO:0009060 55 36 0,000 0,20862651 0,22951778 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,20862651 0,22941288 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,21375659 0,23494671 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,21375659 0,23483943 ! actomyosin structure organization GO:0031032 62 37 0,000 0,21375659 0,23473225 ! organic anion transport GO:0015711 68 37 0,000 0,21375659 0,23462516 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,21375659 0,23451817 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,21375659 0,23441128 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,21375659 0,23430449 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,21375659 0,23419779 ! spermatid differentiation GO:0048515 66 37 0,000 0,21375659 0,2340912 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,21885358 0,23956402 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,21885358 0,23945508 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,21885358 0,23934623 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,21885358 0,23923749 ! lipid homeostasis GO:0055088 67 38 0,000 0,21885358 0,23912884 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,21885358 0,2390203 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,21885358 0,23891185 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,21885358 0,2388035 ! mRNA catabolic process GO:0006402 71 39 0,000 0,2239177 0,24421848 ! learning GO:0007612 77 39 0,000 0,2239177 0,24410783 ! organic ether metabolic process GO:0018904 55 39 0,000 0,2239177 0,24399727 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,2239177 0,24388682 ! ion transmembrane transport GO:0034220 66 39 0,000 0,2239177 0,24377646 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,2239177 0,2436662 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,2239177 0,24355605 ! RNA modification GO:0009451 57 39 0,000 0,2239177 0,24344599 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,2239177 0,24333603 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,22894915 0,24869149 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,22894915 0,24857927 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,22894915 0,24846714 ! feeding behavior GO:0007631 59 40 0,000 0,22894915 0,24835512 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,22894915 0,2482432 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,23394815 0,25354921 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,23394815 0,25343505 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,23394815 0,25332099 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,23394815 0,25320704 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,23394815 0,25309319 ! regulation of tube size GO:0035150 71 42 0,000 0,2389149 0,25835023 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,2389149 0,25823417 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,2389149 0,25811821 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,2389149 0,25800236 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,2389149 0,25788661 ! regulation of protein secretion GO:0050708 71 42 0,000 0,2389149 0,25777097 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,24384962 0,26297722 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,24384962 0,2628594 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,24384962 0,26274169 ! striated muscle contraction GO:0006941 77 43 0,000 0,24384962 0,26262408 ! phagocytosis GO:0006909 90 43 0,000 0,24384962 0,26250657 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,24384962 0,26238917 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,2487525 0,26754516 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,2487525 0,26742561 ! male sex differentiation GO:0046661 76 44 0,000 0,2487525 0,26730617 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,2487525 0,26718684 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,25362376 0,27229753 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,25362376 0,27217608 ! leukocyte migration GO:0050900 68 45 0,000 0,25362376 0,27205473 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,25362376 0,2719335 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,25362376 0,27181237 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,25362376 0,27169135 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,25362376 0,27157043 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,25362376 0,27144963 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,25362376 0,27132893 ! cell growth GO:0016049 84 45 0,000 0,25362376 0,27120834 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,25846359 0,27626095 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,25846359 0,27613828 ! pigmentation GO:0043473 100 46 0,000 0,25846359 0,27601571 ! positive regulation of defense response GO:0031349 76 47 0,000 0,2632722 0,28102613 ! response to calcium ion GO:0051592 81 47 0,000 0,2632722 0,28090151 ! endosome transport GO:0016197 108 47 0,000 0,2632722 0,280777 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,2632722 0,28065259 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,2632722 0,2805283 ! Notch signaling pathway GO:0007219 96 48 0,000 0,26804978 0,28549259 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,26804978 0,28536627 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,26804978 0,28524006 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,26804978 0,28511396 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,27279654 0,29003467 ! regulation of ion transport GO:0043269 77 49 0,000 0,27279654 0,28990657 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,27279654 0,28977857 ! response to temperature stimulus GO:0009266 76 49 0,000 0,27279654 0,28965069 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,27279654 0,28952292 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,27279654 0,28939527 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,27279654 0,28926773 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,27279654 0,28914029 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,27751267 0,29400946 ! neuromuscular process GO:0050905 99 50 0,000 0,27751267 0,29388005 ! regulation of ossification GO:0030278 117 50 0,000 0,27751267 0,29375076 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,28219837 0,29857928 ! excretion GO:0007588 83 51 0,000 0,28219837 0,29844804 ! chromatin remodeling GO:0006338 109 51 0,000 0,28219837 0,29831691 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,28219837 0,2981859 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,28219837 0,298055 ! vesicle organization GO:0016050 107 51 0,000 0,28219837 0,29792421 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,28685384 0,30270629 ! positive regulation of growth GO:0045927 90 52 0,000 0,28685384 0,30257358 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,29147927 0,30731776 ! RNA catabolic process GO:0006401 93 53 0,000 0,29147927 0,30718315 ! regulation of translational initiation GO:0006446 82 53 0,000 0,29147927 0,30704865 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,29147927 0,30691428 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,29147927 0,30678002 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,29147927 0,30664588 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,29147927 0,30651185 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,29607485 0,31120843 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,29607485 0,31107253 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,29607485 0,31093675 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,29607485 0,31080109 ! chloride transport GO:0006821 90 55 0,000 0,30064078 0,31545648 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,30064078 0,31531897 ! gastrulation GO:0007369 112 55 0,000 0,30064078 0,31518157 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,30064078 0,3150443 ! regulation of actin filament length GO:0030832 105 56 0,000 0,30517724 0,31965887 ! sensory perception of smell GO:0007608 80 56 0,000 0,30517724 0,31951977 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,30517724 0,31938079 ! proton transport GO:0015992 94 56 0,000 0,30517724 0,31924193 ! hydrogen transport GO:0006818 97 58 0,000 0,31416251 0,32849848 ! regulation of endocytosis GO:0030100 91 58 0,000 0,31416251 0,32835578 ! adult behavior GO:0030534 99 58 0,000 0,31416251 0,3282132 ! positive regulation of secretion GO:0051047 95 59 0,000 0,31861171 0,33271691 ! regulation of cellular component size GO:0032535 109 59 0,000 0,31861171 0,33257257 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,31861171 0,33242835 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,31861171 0,33228425 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,32303219 0,33674846 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,32303219 0,33660261 ! regulation of heart contraction GO:0008016 110 60 0,000 0,32303219 0,3364569 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,32303219 0,33631131 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,32742413 0,34073636 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,32742413 0,34058904 ! tRNA processing GO:0008033 89 61 0,000 0,32742413 0,34044186 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,32742413 0,3402948 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,33178773 0,34468103 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,33612316 0,34903424 ! detection of external stimulus GO:0009581 91 63 0,000 0,33612316 0,34888366 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,33612316 0,34873321 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,34043061 0,35305002 ! cell redox homeostasis GO:0045454 102 64 0,000 0,34043061 0,35289791 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,34043061 0,35274593 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,34043061 0,35259408 GO:0048609|reproductive process in a multicellular organism, ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,34471025 0,356873 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,34471025 0,35671951 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,34896226 0,3609644 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,34896226 0,36080928 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,35318682 0,3650204 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,35318682 0,36486367 ! activation of immune response GO:0002253 105 67 0,000 0,35318682 0,36470708 ! amino acid transport GO:0006865 125 68 0,000 0,35738411 0,36888296 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,35738411 0,36872478 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,36155431 0,37286741 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,36155431 0,37270765 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,36155431 0,37254803 ! antigen processing and presentation GO:0019882 104 69 0,000 0,36155431 0,37238855 ! amine catabolic process GO:0009310 117 71 0,000 0,36981409 0,38073286 ! humoral immune response GO:0006959 109 71 0,000 0,36981409 0,38057002 ! regulation of immune effector process GO:0002697 137 71 0,000 0,36981409 0,38040731 ! acute inflammatory response GO:0002526 113 72 0,000 0,37390403 0,38445004 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,37390403 0,38428581 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,37796756 0,3882963 ! transition metal ion transport GO:0000041 126 74 0,000 0,38200485 0,39227642 ! neurotransmitter transport GO:0006836 123 74 0,000 0,38200485 0,39210907 ! exocytosis GO:0006887 133 74 0,000 0,38200485 0,39194186 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,38200485 0,39177479 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,38200485 0,39160786 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,38601606 0,39555138 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,38601606 0,39538299 ! rhythmic process GO:0048511 128 75 0,000 0,38601606 0,39521475 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,39000138 0,39912519 ! defense response to bacterium GO:0042742 89 76 0,000 0,39000138 0,39895549 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,39000138 0,39878594 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,39396096 0,40266358 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,39396096 0,4024926 ! blood coagulation GO:0007596 146 78 0,000 0,39789497 0,40633926 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,40180357 0,41015672 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,40180357 0,40998278 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,40180357 0,40980898 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,40180357 0,40963533 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,40568693 0,41341921 ! response to metal ion GO:0010038 140 80 0,000 0,40568693 0,41324418 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,40568693 0,4130693 ! inorganic anion transport GO:0015698 138 80 0,000 0,40568693 0,41289456 ! digestion GO:0007586 112 81 0,000 0,4095452 0,41664514 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,41337856 0,42036721 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,41337856 0,42018961 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,41337856 0,42001217 ! regulation of lyase activity GO:0051339 160 83 0,000 0,41718716 0,42370295 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,42097115 0,42736565 ! hemostasis GO:0007599 158 84 0,000 0,42097115 0,4271854 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,42097115 0,42700531 ! nucleosome assembly GO:0006334 122 85 0,000 0,4247307 0,4306372 ! amine biosynthetic process GO:0009309 138 86 0,000 0,42846597 0,43424142 ! response to inorganic substance GO:0010035 153 86 0,000 0,42846597 0,43405858 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,42846597 0,43387589 ! chromatin assembly GO:0031497 124 86 0,000 0,42846597 0,43369336 ! amine transport GO:0015837 155 86 0,000 0,42846597 0,43351099 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,43217711 0,43708202 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,43217711 0,43689837 ! cellular respiration GO:0045333 135 88 0,000 0,43586427 0,44044075 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,43586427 0,44025585 ! regulation of neurological system process GO:0031644 148 88 0,000 0,43586427 0,4400711 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,43586427 0,43988651 ! cellular defense response GO:0006968 114 89 0,000 0,43952761 0,44339766 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,44316728 0,44688201 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,44316728 0,4466948 ! sterol metabolic process GO:0016125 152 91 0,000 0,44678344 0,45015115 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,44678344 0,44996273 ! regulation of defense response GO:0031347 149 92 0,000 0,45037623 0,45339131 ! nucleosome organization GO:0034728 138 92 0,000 0,45037623 0,45320168 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,45037623 0,45301222 ! vitamin metabolic process GO:0006766 139 92 0,000 0,45037623 0,45282291 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,45394581 0,45622123 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,45394581 0,45603074 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,45749233 0,45940173 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,46101593 0,4627469 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,46451676 0,46606644 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,46451676 0,46587216 ! detection of stimulus GO:0051606 151 96 0,000 0,46451676 0,46567805 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,46799496 0,46896955 ! response to virus GO:0009615 160 98 0,000 0,47145069 0,47223579 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,47145069 0,47203927 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,47145069 0,47184291 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,47488409 0,47508154 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,47488409 0,47488409