pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6578-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! mitotic sister chromatid segregation GO:0000070 45 32 5,000 9,665E-08 2,223E-04 ! sister chromatid segregation GO:0000819 46 33 5,000 1,174E-07 1,351E-04 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 6,000 2,403E-07 1,842E-04 ! negative regulation of ligase activity GO:0051352 91 61 6,000 2,698E-07 1,552E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 6,000 2,698E-07 1,241E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 6,000 4,204E-07 1,612E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 6,000 7,749E-07 2,546E-04 ! regulation of ligase activity GO:0051340 114 75 6,000 1,129E-06 3,247E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 6,000 1,754E-06 4,484E-04 GO:0010498|proteasomal protein catabolic process, ! spindle organization GO:0007051 37 30 4,000 2,215E-06 5,094E-04 ! chromosome segregation GO:0007059 83 57 5,000 3,341E-06 6,985E-04 ! mitotic chromosome condensation GO:0007076 25 16 3,000 4,378E-06 8,392E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 5,000 5,496E-06 9,723E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 5,000 7,255E-06 1,192E-03 ! positive regulation of ligase activity GO:0051351 99 69 5,000 1,028E-05 1,577E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 5,000 1,118E-05 1,608E-03 ! chromosome condensation GO:0030261 31 20 3,000 1,14E-05 1,542E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 2,000 1,253E-05 1,601E-03 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 2,000 1,994E-05 2,414E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 1,994E-05 2,293E-03 ! SMAD protein nuclear translocation GO:0007184 15 9 2,000 2,975E-05 3,258E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 2,000 4,228E-05 4,42E-03 ! detection of bacterium GO:0016045 10 10 2,000 4,228E-05 4,228E-03 ! mitotic spindle organization GO:0007052 15 11 2,000 5,783E-05 5,542E-03 ! positive regulation of protein import into nucleus GO:0042307 23 13 2,000 9,918E-05 9,124E-03 ! epidermis morphogenesis GO:0048730 29 14 2,000 1,256E-04 0,01110756 ! response to drug GO:0042493 108 69 4,000 1,396E-04 0,01188843 ! negative regulation of cell cycle process GO:0010948 24 15 2,000 1,561E-04 0,01282489 ! patterning of blood vessels GO:0001569 24 16 2,000 1,911E-04 0,01516005 ! protein export from nucleus GO:0006611 24 16 2,000 1,911E-04 0,01465472 ! detection of biotic stimulus GO:0009595 19 16 2,000 1,911E-04 0,01418199 ! phosphatidylinositol metabolic process GO:0046488 22 17 2,000 2,309E-04 0,01659513 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 2,309E-04 0,01609225 ! branching morphogenesis of a tube GO:0048754 72 42 3,000 2,329E-04 0,01575793 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 2,000 2,756E-04 0,01811156 ! positive regulation of cell cycle GO:0045787 77 45 3,000 3,05E-04 0,01948318 ! calcium-independent cell-cell adhesion GO:0016338 21 19 2,000 3,256E-04 0,02023804 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 2,000 3,256E-04 0,01970546 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 3,256E-04 0,01920019 ! microtubule cytoskeleton organization GO:0000226 120 84 4,000 3,518E-04 0,02022678 ! collagen fibril organization GO:0030199 45 20 2,000 3,81E-04 0,02137374 ! cell cycle arrest GO:0007050 150 86 4,000 3,923E-04 0,02148347 ! morphogenesis of a branching structure GO:0001763 86 49 3,000 4,241E-04 0,02268591 ! SMAD protein complex assembly GO:0007183 9 5 1,000 5,081E-04 0,02655984 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 5,081E-04 0,02596962 ! serotonin receptor signaling pathway GO:0007210 8 5 1,000 5,081E-04 0,02540507 ! embryonic hemopoiesis GO:0035162 10 5 1,000 5,081E-04 0,02486453 ! response to protozoan GO:0001562 9 5 1,000 5,081E-04 0,02434652 ! positive regulation of neurotransmitter secretion GO:0001956 10 5 1,000 5,081E-04 0,02384966 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 1,000 5,081E-04 0,02337266 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! valine metabolic process GO:0006573 8 5 1,000 5,081E-04 0,02291437 ! polyol catabolic process GO:0046174 7 5 1,000 5,081E-04 0,02247371 GO:0019405|alditol catabolic process, ! sister chromatid cohesion GO:0007062 9 5 1,000 5,081E-04 0,02204968 ! melanosome organization GO:0032438 7 5 1,000 5,081E-04 0,02164135 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 5,081E-04 0,02124787 ! early endosome to late endosome transport GO:0045022 11 5 1,000 5,081E-04 0,02086845 ! regulation of centrosome cycle GO:0046605 7 5 1,000 5,081E-04 0,02050234 ! neural tube patterning GO:0021532 6 5 1,000 5,081E-04 0,02014885 ! muscle cell proliferation GO:0033002 8 5 1,000 5,081E-04 0,01980734 ! regulation of hair follicle development GO:0051797 9 5 1,000 5,081E-04 0,01947722 GO:0042634|regulation of hair cycle, ! glial cell migration GO:0008347 10 5 1,000 5,081E-04 0,01915792 ! regulation of sensory perception GO:0051931 6 5 1,000 5,081E-04 0,01884892 GO:0051930|regulation of sensory perception of pain, ! organ regeneration GO:0031100 7 5 1,000 5,081E-04 0,01854973 ! RNA localization GO:0006403 135 91 4,000 5,091E-04 0,01829485 ! protein import into nucleus, translocation GO:0000060 36 22 2,000 5,093E-04 0,0180217 ! vasculogenesis GO:0001570 33 22 2,000 5,093E-04 0,01774865 ! regulation of transcription factor import into nucleus GO:0042990 46 23 2,000 5,826E-04 0,02000082 ! prostate gland development GO:0030850 9 6 1,000 7,586E-04 0,02565696 ! regulation of dopamine metabolic process GO:0042053 9 6 1,000 7,586E-04 0,02528512 GO:0042069|regulation of catecholamine metabolic process, ! inositol phosphate-mediated signaling GO:0048016 9 6 1,000 7,586E-04 0,0249239 ! pigment granule organization GO:0048753 11 6 1,000 7,586E-04 0,02457286 ! positive regulation of insulin secretion GO:0032024 8 6 1,000 7,586E-04 0,02423157 ! spindle checkpoint GO:0031577 14 6 1,000 7,586E-04 0,02389963 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 7,586E-04 0,02357667 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 1,000 7,586E-04 0,02326231 ! midbrain development GO:0030901 6 6 1,000 7,586E-04 0,02295623 ! myeloid leukocyte activation GO:0002274 39 28 2,000 1,05E-03 0,03135781 ! glycerol-3-phosphate metabolic process GO:0006072 9 7 1,000 1,057E-03 0,03116688 ! regulation of cellular amine metabolic process GO:0033238 10 7 1,000 1,057E-03 0,03077237 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 1,057E-03 0,03038771 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 1,057E-03 0,03001255 ! positive regulation of neurotransmitter transport GO:0051590 15 7 1,000 1,057E-03 0,02964655 ! regulation of defense response to virus by virus GO:0050690 16 7 1,000 1,057E-03 0,02928936 ! protein retention in ER lumen GO:0006621 12 7 1,000 1,057E-03 0,02894068 ! positive regulation of epidermis development GO:0045684 11 7 1,000 1,057E-03 0,0286002 ! dopamine biosynthetic process GO:0042416 15 7 1,000 1,057E-03 0,02826764 ! behavioral response to nicotine GO:0035095 11 7 1,000 1,057E-03 0,02794272 ! regulation of protein import into nucleus GO:0042306 53 29 2,000 1,165E-03 0,03044376 ! cell cycle checkpoint GO:0000075 108 64 3,000 1,17E-03 0,03024651 ! succinate metabolic process GO:0006105 14 8 1,000 1,403E-03 0,03584521 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,403E-03 0,03545131 ! endothelial cell differentiation GO:0045446 14 8 1,000 1,403E-03 0,03506597 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 1,000 1,403E-03 0,03468891 ! macrophage activation GO:0042116 12 8 1,000 1,403E-03 0,03431988 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,403E-03 0,03395862 ! leukocyte chemotaxis GO:0030595 43 31 2,000 1,418E-03 0,03397136 GO:0060326|cell chemotaxis, ! activation of protein kinase activity GO:0032147 102 69 3,000 1,549E-03 0,03672968 ! carbohydrate homeostasis GO:0033500 39 33 2,000 1,703E-03 0,03997125 GO:0042593|glucose homeostasis, ! steroid biosynthetic process GO:0006694 94 71 3,000 1,722E-03 0,0400028 ! artery development GO:0060840 19 9 1,000 1,795E-03 0,04128252 GO:0048844|artery morphogenesis, ! phosphagen metabolic process GO:0006599 12 9 1,000 1,795E-03 0,04087379 GO:0006600|creatine metabolic process, ! epithelial cell development GO:0002064 10 9 1,000 1,795E-03 0,04047306 ! positive regulation of peptide secretion GO:0002793 15 9 1,000 1,795E-03 0,04008012 ! regulation of hormone metabolic process GO:0032350 15 9 1,000 1,795E-03 0,03969473 ! thymus development GO:0048538 15 9 1,000 1,795E-03 0,03931669 ! pyrimidine base metabolic process GO:0006206 14 9 1,000 1,795E-03 0,03894578 ! natural killer cell mediated immunity GO:0002228 13 9 1,000 1,795E-03 0,0385818 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of amino acid transport GO:0051955 11 9 1,000 1,795E-03 0,03822456 ! positive regulation of amine transport GO:0051954 15 9 1,000 1,795E-03 0,03787387 ! response to nicotine GO:0035094 16 9 1,000 1,795E-03 0,03752957 ! negative regulation of organelle organization GO:0010639 115 72 3,000 1,813E-03 0,03756873 ! mitotic cell cycle checkpoint GO:0007093 63 34 2,000 1,858E-03 0,03815897 ! tube morphogenesis GO:0035239 118 73 3,000 1,908E-03 0,03882806 ! protein import into nucleus GO:0006606 118 74 3,000 2,006E-03 0,04046265 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 2,022E-03 0,04043517 ! nuclear import GO:0051170 121 75 3,000 2,107E-03 0,04177399 ! regulation of phosphatase activity GO:0010921 21 10 1,000 2,233E-03 0,04389748 ! hair follicle morphogenesis GO:0031069 17 10 1,000 2,233E-03 0,04352547 ! positive regulation of heart contraction GO:0045823 14 10 1,000 2,233E-03 0,04315971 ! nucleobase biosynthetic process GO:0046112 21 10 1,000 2,233E-03 0,04280005 ! DNA methylation GO:0006306 15 10 1,000 2,233E-03 0,04244633 GO:0006305|DNA alkylation, ! salivary gland development GO:0007431 22 10 1,000 2,233E-03 0,04209841 ! gland development GO:0048732 148 77 3,000 2,32E-03 0,04338234 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 2,000 2,565E-03 0,04758169 ! pigmentation GO:0043473 74 38 2,000 2,565E-03 0,04720104 ! protein localization in nucleus GO:0034504 133 80 3,000 2,667E-03 0,04868155 ! virus-host interaction GO:0019048 17 11 1,000 2,716E-03 0,04919516 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 1,000 2,716E-03 0,04881082 ! focal adhesion formation GO:0048041 24 11 1,000 2,716E-03 0,04843244 ! cellular carbohydrate catabolic process GO:0044275 13 11 1,000 2,716E-03 0,04805988 ! L-glutamate transport GO:0015813 16 11 1,000 2,716E-03 0,04769301 GO:0015800|acidic amino acid transport, ! T cell homeostasis GO:0043029 20 11 1,000 2,716E-03 0,0473317 ! leukocyte mediated cytotoxicity GO:0001909 17 11 1,000 2,716E-03 0,04697583 ! regulation of organic acid transport GO:0032890 17 11 1,000 2,716E-03 0,04662526 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 2,000 2,765E-03 0,0470996 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 2,765E-03 0,04675328 ! regulation of cell cycle process GO:0010564 122 81 3,000 2,79E-03 0,04683965 ! positive regulation of protein transport GO:0051222 55 40 2,000 2,973E-03 0,04955167 ! epithelial cell differentiation GO:0030855 55 41 2,000 3,191E-03 0,05280216 ! heart looping GO:0001947 15 12 1,000 3,244E-03 0,05330044 ! palate development GO:0060021 15 12 1,000 3,244E-03 0,05292243 ! positive regulation of cell growth GO:0030307 16 12 1,000 3,244E-03 0,05254973 ! gland morphogenesis GO:0022612 23 12 1,000 3,244E-03 0,05218225 ! regulation of epidermis development GO:0045682 17 12 1,000 3,244E-03 0,05181988 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 3,419E-03 0,05422665 ! leukocyte migration GO:0050900 60 43 2,000 3,656E-03 0,0575926 ! establishment of RNA localization GO:0051236 128 88 3,000 3,763E-03 0,05886928 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 1,000 3,816E-03 0,05930625 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 1,000 3,816E-03 0,05890823 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! exocrine system development GO:0035272 27 13 1,000 3,816E-03 0,0585155 ! negative regulation of mitotic cell cycle GO:0045930 23 13 1,000 3,816E-03 0,05812798 ! cellular pigmentation GO:0033059 24 13 1,000 3,816E-03 0,05774556 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 1,000 3,816E-03 0,05736814 ! lymphocyte homeostasis GO:0002260 24 13 1,000 3,816E-03 0,05699562 ! regulation of defense response to virus GO:0050688 24 14 1,000 4,431E-03 0,06575536 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 1,000 4,431E-03 0,06533385 ! catecholamine biosynthetic process GO:0042423 23 14 1,000 4,431E-03 0,06491771 ! cell killing GO:0001906 20 14 1,000 4,431E-03 0,06450684 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 4,431E-03 0,06410114 ! angiogenesis GO:0001525 149 95 3,000 4,943E-03 0,07104997 ! heart morphogenesis GO:0003007 65 48 2,000 4,992E-03 0,07131028 ! nuclear export GO:0051168 69 48 2,000 4,992E-03 0,07087009 ! positive regulation of cell size GO:0045793 20 15 1,000 5,089E-03 0,07180888 ! skin development GO:0043588 25 15 1,000 5,089E-03 0,07137102 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 5,089E-03 0,07093847 ! regulation of neurotransmitter secretion GO:0046928 26 15 1,000 5,089E-03 0,07051113 ! myoblast differentiation GO:0045445 27 15 1,000 5,089E-03 0,07008891 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 1,000 5,089E-03 0,06967171 ! neuron recognition GO:0008038 22 15 1,000 5,089E-03 0,06925945 ! dopamine metabolic process GO:0042417 30 15 1,000 5,089E-03 0,06885204 ! regulation of BMP signaling pathway GO:0030510 21 15 1,000 5,089E-03 0,0684494 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 5,089E-03 0,06805144 ! defense response to virus GO:0051607 27 15 1,000 5,089E-03 0,06765808 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 3,000 5,129E-03 0,06780019 ! regulation of intracellular transport GO:0032386 78 49 2,000 5,29E-03 0,06952053 ! positive regulation of growth GO:0045927 67 50 2,000 5,598E-03 0,07315538 ! protein import GO:0017038 156 99 3,000 5,717E-03 0,07429287 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 1,000 5,789E-03 0,07479867 ! regulation of dephosphorylation GO:0035303 33 16 1,000 5,789E-03 0,0743808 ! negative regulation of immune response GO:0050777 28 16 1,000 5,789E-03 0,07396757 ! neutrophil chemotaxis GO:0030593 21 16 1,000 5,789E-03 0,07355891 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 5,789E-03 0,07315474 ! positive regulation of secretion GO:0051047 71 51 2,000 5,917E-03 0,07436579 ! positive regulation of cell migration GO:0030335 92 51 2,000 5,917E-03 0,07396163 ! positive regulation of organelle organization GO:0010638 82 51 2,000 5,917E-03 0,07356184 ! protein localization in organelle GO:0033365 161 100 3,000 5,923E-03 0,07324048 ! positive regulation of hormone secretion GO:0046887 24 17 1,000 6,53E-03 0,08031325 ! glycerol metabolic process GO:0006071 20 17 1,000 6,53E-03 0,07988605 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 1,000 6,53E-03 0,07946338 ! forelimb morphogenesis GO:0035136 19 17 1,000 6,53E-03 0,07904515 ! inactivation of MAPK activity GO:0000188 27 17 1,000 6,53E-03 0,0786313 ! cell-substrate junction assembly GO:0007044 39 17 1,000 6,53E-03 0,07822176 ! actin filament bundle formation GO:0051017 26 17 1,000 6,53E-03 0,07781647 ! nucleobase metabolic process GO:0009112 31 17 1,000 6,53E-03 0,07741535 ! proximal/distal pattern formation GO:0009954 25 17 1,000 6,53E-03 0,07701835 ! regulation of mitosis GO:0007088 84 54 2,000 6,938E-03 0,08141769 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 66 54 2,000 6,938E-03 0,0810044 ! pancreas development GO:0031016 26 18 1,000 7,312E-03 0,08493264 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 7,312E-03 0,08450584 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 1,000 7,312E-03 0,08408331 ! positive regulation of cell motion GO:0051272 99 56 2,000 7,674E-03 0,08780718 ! protein import into nucleus, docking GO:0000059 30 19 1,000 8,133E-03 0,0926089 ! positive regulation of ossification GO:0045778 30 19 1,000 8,133E-03 0,0921527 ! regeneration GO:0031099 32 19 1,000 8,133E-03 0,09170097 ! response to alkaloid GO:0043279 32 19 1,000 8,133E-03 0,09125365 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 8,133E-03 0,09081067 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 1,000 8,133E-03 0,09037197 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 1,000 8,133E-03 0,08993749 ! regulation of neurotransmitter transport GO:0051588 35 20 1,000 8,995E-03 0,09898653 ! DNA modification GO:0006304 28 20 1,000 8,995E-03 0,09851516 ! alditol metabolic process GO:0019400 24 20 1,000 8,995E-03 0,09804827 ! phosphoinositide metabolic process GO:0030384 87 60 2,000 9,278E-03 0,1006574 ! meiosis GO:0007126 96 61 2,000 9,707E-03 0,10482091 GO:0051327|M phase of meiotic cell cycle, ! extracellular matrix organization GO:0030198 103 61 2,000 9,707E-03 0,10433109 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 9,895E-03 0,10585504 ! myeloid leukocyte differentiation GO:0002573 33 21 1,000 9,895E-03 0,10536497 ! gluconeogenesis GO:0006094 25 21 1,000 9,895E-03 0,10487942 ! positive regulation of bone remodeling GO:0046852 33 21 1,000 9,895E-03 0,10439832 GO:0034105|positive regulation of tissue remodeling, ! regulation of insulin secretion GO:0050796 26 21 1,000 9,895E-03 0,10392162 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 9,895E-03 0,10344925 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 9,895E-03 0,10298115 ! regulation of vasoconstriction GO:0019229 31 21 1,000 9,895E-03 0,10251727 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 9,895E-03 0,10205755 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 1,000 9,895E-03 0,10160194 ! regulation of multi-organism process GO:0043900 32 21 1,000 9,895E-03 0,10115037 ! negative regulation of cell growth GO:0030308 106 62 2,000 0,01014809 0,103277 ! meiotic cell cycle GO:0051321 97 62 2,000 0,01014809 0,10282204 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 0,01083373 0,10928762 ! regulation of transmembrane transport GO:0034762 30 22 1,000 0,01083373 0,10881038 ! molting cycle process GO:0022404 40 22 1,000 0,01083373 0,10833729 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 0,01083373 0,1078683 ! barbed-end actin filament capping GO:0051016 33 22 1,000 0,01083373 0,10740335 GO:0051693|actin filament capping, ! leukocyte homeostasis GO:0001776 33 22 1,000 0,01083373 0,10694239 ! negative regulation of cell size GO:0045792 108 64 2,000 0,01106409 0,10874962 ! regulation of caspase activity GO:0043281 97 65 2,000 0,01153944 0,11293918 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 0,01181002 0,11509769 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01181002 0,11461205 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 0,01181002 0,11413048 ! interaction with host GO:0051701 37 23 1,000 0,01181002 0,11365295 ! cellular response to oxidative stress GO:0034599 33 23 1,000 0,01181002 0,11317939 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 0,01181002 0,11270977 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 1,000 0,01181002 0,11224403 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! regulation of response to biotic stimulus GO:0002831 35 23 1,000 0,01181002 0,11178212 ! regulation of amine transport GO:0051952 38 23 1,000 0,01181002 0,111324 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01252505 0,11758215 ! pyruvate metabolic process GO:0006090 29 24 1,000 0,01282345 0,11989401 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 0,01282345 0,11940861 ! fat cell differentiation GO:0045444 37 24 1,000 0,01282345 0,11892713 ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 0,01282345 0,11844951 ! intracellular protein transmembrane transport GO:0065002 102 68 2,000 0,01303541 0,11992579 ! negative regulation of actin filament depolymerization GO:0030835 36 25 1,000 0,01387342 0,12712696 ! negative regulation of actin filament polymerization GO:0030837 36 25 1,000 0,01387342 0,12662249 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 0,01387342 0,126122 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of peptide secretion GO:0002791 34 25 1,000 0,01387342 0,12562546 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,01387342 0,12513281 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 0,01387342 0,12464401 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01387342 0,12415901 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 0,01387342 0,12367778 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,01495937 0,13284386 ! negative regulation of protein modification process GO:0031400 50 26 1,000 0,01495937 0,13233292 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,01495937 0,1318259 ! negative regulation of protein polymerization GO:0032272 38 26 1,000 0,01495937 0,13132275 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,0151947 0,13288138 ! response to hypoxia GO:0001666 132 72 2,000 0,0151947 0,13237804 ! regulation of actin filament depolymerization GO:0030834 39 27 1,000 0,01608074 0,13956871 ! catechol metabolic process GO:0009712 43 27 1,000 0,01608074 0,13904402 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to oxygen levels GO:0070482 137 74 2,000 0,01634549 0,14080386 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 0,01634549 0,14027847 ! negative regulation of growth GO:0045926 123 75 2,000 0,01693877 0,14482961 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,01723697 0,14683344 ! phenol metabolic process GO:0018958 44 28 1,000 0,01723697 0,14629162 ! negative regulation of protein complex assembly GO:0031333 42 28 1,000 0,01723697 0,14575378 ! cell junction assembly GO:0034329 56 28 1,000 0,01723697 0,14521988 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,01723697 0,14468988 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,01723697 0,14416374 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 0,01723697 0,14364141 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 0,01723697 0,14312284 ! regulation of protein transport GO:0051223 114 76 2,000 0,01754399 0,14514813 GO:0070201|regulation of establishment of protein localization, ! hexose biosynthetic process GO:0019319 35 29 1,000 0,0184275 0,15191129 ! organic anion transport GO:0015711 51 30 1,000 0,01965179 0,16142541 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 0,01965179 0,16085094 ! hindbrain development GO:0030902 45 30 1,000 0,01965179 0,16028054 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,01965179 0,15971418 ! mRNA transport GO:0051028 121 81 2,000 0,02074986 0,16804461 ! mammary gland development GO:0030879 57 31 1,000 0,0209093 0,16874168 ! odontogenesis GO:0042476 50 31 1,000 0,0209093 0,16815168 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,0209093 0,16756578 ! biogenic amine biosynthetic process GO:0042401 44 31 1,000 0,0209093 0,16698396 ! detection of stimulus GO:0051606 108 82 2,000 0,02142705 0,17052674 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,02219949 0,17606489 ! meiosis I GO:0007127 52 32 1,000 0,02219949 0,17545986 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,02219949 0,17485897 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,02219949 0,17426218 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,02219949 0,17366945 ! RNA export from nucleus GO:0006405 44 33 1,000 0,02352183 0,18339056 ! cell junction organization GO:0034330 63 33 1,000 0,02352183 0,182771 ! positive regulation of cell development GO:0010720 54 33 1,000 0,02352183 0,1821556 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,02352183 0,18154434 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,02352183 0,18093717 ! cytokinesis GO:0000910 52 33 1,000 0,02352183 0,18033405 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 1,000 0,02352183 0,17973493 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 0,0235308 0,17920804 ! regulation of protein localization GO:0032880 132 85 2,000 0,0235308 0,1786166 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,02487581 0,18820515 ! feeding behavior GO:0007631 45 34 1,000 0,02487581 0,18758808 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 0,02487581 0,18697505 ! polyol metabolic process GO:0019751 44 34 1,000 0,02487581 0,18636601 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,02487581 0,18576093 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,02487581 0,18515976 ! embryonic organ development GO:0048568 45 34 1,000 0,02487581 0,18456247 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 0,02487581 0,18396902 ! maintenance of protein location GO:0045185 65 35 1,000 0,02626091 0,19359001 ! Rho protein signal transduction GO:0007266 51 35 1,000 0,02626091 0,19297151 ! protein homooligomerization GO:0051260 52 35 1,000 0,02626091 0,19235695 ! response to reactive oxygen species GO:0000302 55 36 1,000 0,0276766 0,20208314 ! regulation of hormone secretion GO:0046883 48 36 1,000 0,0276766 0,20144363 ! cellular amide metabolic process GO:0043603 52 36 1,000 0,0276766 0,20080816 ! neural tube development GO:0021915 50 36 1,000 0,0276766 0,20017669 ! response to virus GO:0009615 122 91 2,000 0,02806269 0,20233286 ! glycerophospholipid metabolic process GO:0006650 130 92 2,000 0,02885996 0,20743097 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,0291224 0,20866518 ! ribonucleoside metabolic process GO:0009119 48 37 1,000 0,0291224 0,20801715 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 0,02966919 0,21126667 ! gliogenesis GO:0042063 71 38 1,000 0,0305978 0,21720658 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,0305978 0,21653825 ! phagocytosis GO:0006909 60 38 1,000 0,0305978 0,21587403 ! mesenchymal cell development GO:0014031 64 38 1,000 0,0305978 0,21521386 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 1,000 0,0305978 0,21455772 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 0,0321023 0,22442335 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,0321023 0,22374328 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 1,000 0,0321023 0,22306732 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,0321023 0,22239543 ! cell growth GO:0016049 61 39 1,000 0,0321023 0,22172758 ! regulation of actin filament polymerization GO:0030833 59 40 1,000 0,03363541 0,2316211 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 0,03363541 0,2309297 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,03363541 0,23024241 ! extracellular structure organization GO:0043062 156 99 2,000 0,03477447 0,23733316 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,03477447 0,23663099 ! endosome transport GO:0016197 71 41 1,000 0,03519666 0,2387974 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,03519666 0,23809505 ! biopolymer methylation GO:0043414 62 41 1,000 0,03519666 0,23739683 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03552534 0,23891307 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03552534 0,23821653 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03552534 0,23752404 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03552534 0,23683557 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03552534 0,23615107 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03552534 0,23547052 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03552534 0,23479388 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03552534 0,23412112 ! sleep GO:0030431 11 5 0,000 0,03552534 0,2334522 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03552534 0,2327871 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03552534 0,23212577 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03552534 0,23146819 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03552534 0,23081432 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03552534 0,23016414 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03552534 0,22951761 ! tongue development GO:0043586 6 5 0,000 0,03552534 0,22887471 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03552534 0,22823539 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03552534 0,22759964 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03552534 0,22696742 ! cobalt ion transport GO:0006824 9 5 0,000 0,03552534 0,2263387 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03552534 0,22571345 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03552534 0,22509165 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03552534 0,22447327 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03552534 0,22385828 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03552534 0,22324664 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03552534 0,22263834 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03552534 0,22203334 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03552534 0,22143163 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03552534 0,22083316 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03552534 0,22023793 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,03552534 0,21964589 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03552534 0,21905703 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03552534 0,21847131 ! malate metabolic process GO:0006108 7 5 0,000 0,03552534 0,21788872 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03552534 0,21730923 ! behavioral response to pain GO:0048266 7 5 0,000 0,03552534 0,21673281 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03552534 0,21615945 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03552534 0,2155891 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03552534 0,21502176 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03552534 0,2144574 ! mating behavior GO:0007617 6 5 0,000 0,03552534 0,213896 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03552534 0,21333752 ! rhythmic behavior GO:0007622 12 5 0,000 0,03552534 0,21278195 ! copulation GO:0007620 7 5 0,000 0,03552534 0,21222927 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03552534 0,21167946 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03552534 0,21113248 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03552534 0,21058833 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03552534 0,21004697 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03552534 0,20950839 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03552534 0,20897256 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03552534 0,20843947 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03552534 0,20790909 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,03552534 0,2073814 ! lymph vessel development GO:0001945 7 5 0,000 0,03552534 0,20685638 ! endochondral ossification GO:0001958 12 5 0,000 0,03552534 0,20633402 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! parathyroid gland development GO:0060017 8 5 0,000 0,03552534 0,20581428 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03552534 0,20529716 ! anagen GO:0042640 6 5 0,000 0,03552534 0,20478263 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03552534 0,20427068 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03552534 0,20376127 ! nuclear migration GO:0007097 10 5 0,000 0,03552534 0,2032544 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03552534 0,20275005 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03552534 0,20224819 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03552534 0,20174882 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03552534 0,2012519 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03552534 0,20075742 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03552534 0,20026537 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03552534 0,19977572 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03552534 0,19928846 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,03552534 0,19880358 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03552534 0,19832105 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03552534 0,19784085 ! ovulation GO:0030728 6 5 0,000 0,03552534 0,19736297 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03552534 0,1968874 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,03552534 0,19641411 GO:0030033|microvillus assembly, ! response to pH GO:0009268 9 5 0,000 0,03552534 0,19594309 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03552534 0,19547433 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03552534 0,19500781 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03552534 0,1945435 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03552534 0,1940814 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03552534 0,19362149 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03552534 0,19316376 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03552534 0,19270819 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03552534 0,19225475 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03552534 0,19180345 ! urea metabolic process GO:0019627 6 5 0,000 0,03552534 0,19135426 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03552534 0,19090717 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03552534 0,19046217 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03552534 0,19001923 ! neutrophil activation GO:0042119 5 5 0,000 0,03552534 0,18957835 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03552534 0,18913952 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03552534 0,1887027 ! response to food GO:0032094 5 5 0,000 0,03552534 0,1882679 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03552534 0,1878351 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03552534 0,18740429 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03552534 0,18697545 ! forebrain neuron development GO:0021884 7 5 0,000 0,03552534 0,18654856 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03552534 0,18612362 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03552534 0,18570061 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03552534 0,18527953 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03552534 0,18486034 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,03552534 0,18444305 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03552534 0,18402764 ! nucleoside transport GO:0015858 6 5 0,000 0,03552534 0,18361409 ! nucleoside salvage GO:0043174 7 5 0,000 0,03552534 0,1832024 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03552534 0,18279255 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03552534 0,18238453 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03552534 0,18197833 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03552534 0,18157393 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03552534 0,18117133 ! depyrimidination GO:0045008 8 5 0,000 0,03552534 0,18077051 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03552534 0,18037146 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03552534 0,17997416 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03552534 0,17957862 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03552534 0,1791848 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03552534 0,17879271 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,03552534 0,17840234 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03552534 0,17801366 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03552534 0,17762668 ! monocyte differentiation GO:0030224 8 5 0,000 0,03552534 0,17724137 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03552534 0,17685773 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03552534 0,17647575 ! centrosome duplication GO:0051298 5 5 0,000 0,03552534 0,17609541 ! response to UV-C GO:0010225 6 5 0,000 0,03552534 0,17571671 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03552534 0,17533964 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03552534 0,17496418 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03552534 0,17459032 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03552534 0,17421806 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03552534 0,17384738 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03552534 0,17347828 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03552534 0,17311074 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03552534 0,17274476 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03552534 0,17238032 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03552534 0,17201741 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03552534 0,17165603 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03552534 0,17129616 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03552534 0,1709378 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03552534 0,17058094 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03552534 0,17022556 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03552534 0,16987166 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03552534 0,16951923 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03552534 0,16916826 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03552534 0,16881874 ! histone demethylation GO:0016577 9 5 0,000 0,03552534 0,16847066 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03552534 0,16812401 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03552534 0,16777879 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03552534 0,16743498 ! enteric nervous system development GO:0048484 8 5 0,000 0,03552534 0,16709258 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03552534 0,16675157 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03552534 0,16641196 ! transcription termination GO:0006353 8 5 0,000 0,03552534 0,16607372 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03552534 0,16573686 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03552534 0,16540136 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03552534 0,16506721 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,03552534 0,16473442 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03552534 0,16440296 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03552534 0,16407283 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03552534 0,16374403 GO:0015991|ATP hydrolysis coupled proton transport, ! protein destabilization GO:0031648 6 5 0,000 0,03552534 0,16341654 ! apical protein localization GO:0045176 6 5 0,000 0,03552534 0,16309036 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03552534 0,16276548 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03552534 0,16244189 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03552534 0,16211958 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03552534 0,16179856 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03552534 0,1614788 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03552534 0,1611603 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03552534 0,16084305 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03552534 0,16052705 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,03552534 0,1602123 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03552534 0,15989877 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03552534 0,15958647 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03552534 0,15927538 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03552534 0,15896551 ! neural plate development GO:0001840 6 5 0,000 0,03552534 0,15865684 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03552534 0,15834936 ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03552534 0,15804308 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03552534 0,15773797 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,03552534 0,15743405 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03552534 0,15713129 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03552534 0,15682969 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03552534 0,15652925 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03552534 0,15622996 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03552534 0,15593181 ! spindle assembly GO:0051225 5 5 0,000 0,03552534 0,1556348 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03552534 0,15533892 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03552534 0,15504416 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03552534 0,15475051 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03552534 0,15445798 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03552534 0,15416655 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03552534 0,15387622 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03552534 0,15358697 GO:0055081|anion homeostasis, ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,03678556 0,15873694 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,03678556 0,15843968 ! embryonic skeletal system development GO:0048706 56 42 1,000 0,03678556 0,15814353 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,03678556 0,15784849 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 0,03840164 0,16447631 ! activation of caspase activity GO:0006919 65 43 1,000 0,03840164 0,16417059 ! vesicle organization GO:0016050 79 43 1,000 0,03840164 0,16386601 ! response to insulin stimulus GO:0032868 63 43 1,000 0,03840164 0,16356255 ! methylation GO:0032259 64 43 1,000 0,03840164 0,16326022 ! cell recognition GO:0008037 58 45 1,000 0,04171349 0,17701295 ! cell maturation GO:0048469 60 45 1,000 0,04171349 0,17668695 ! tRNA transcription GO:0009304 11 6 0,000 0,04247869 0,17959741 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04247869 0,17926787 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04247869 0,17893954 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04247869 0,17861241 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04247869 0,17828648 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04247869 0,17796173 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04247869 0,17763816 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04247869 0,17731577 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04247869 0,17699455 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04247869 0,17667448 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04247869 0,17635558 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04247869 0,17603782 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04247869 0,17572121 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04247869 0,17540573 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04247869 0,17509138 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,04247869 0,17477816 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04247869 0,17446605 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04247869 0,17415506 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04247869 0,17384518 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04247869 0,17353639 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04247869 0,17322871 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,04247869 0,17292211 ! neuron adhesion GO:0007158 9 6 0,000 0,04247869 0,17261659 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,04247869 0,17231215 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04247869 0,17200879 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04247869 0,17170649 ! signal peptide processing GO:0006465 8 6 0,000 0,04247869 0,17140525 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04247869 0,17110506 ! mRNA stabilization GO:0048255 15 6 0,000 0,04247869 0,17080593 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04247869 0,17050784 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04247869 0,17021078 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04247869 0,16991477 ! opsonization GO:0008228 8 6 0,000 0,04247869 0,16961977 ! erythrocyte maturation GO:0043249 6 6 0,000 0,04247869 0,16932581 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04247869 0,16903285 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04247869 0,16874092 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04247869 0,16844998 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04247869 0,16816005 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04247869 0,16787112 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04247869 0,16758317 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04247869 0,16729622 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04247869 0,16701024 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04247869 0,16672524 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04247869 0,16644121 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04247869 0,16615815 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04247869 0,16587604 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04247869 0,1655949 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04247869 0,1653147 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04247869 0,16503546 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04247869 0,16475715 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04247869 0,16447978 ! thymic T cell selection GO:0045061 12 6 0,000 0,04247869 0,16420334 ! protein lipoylation GO:0009249 10 6 0,000 0,04247869 0,16392784 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04247869 0,16365325 ! drug transport GO:0015893 6 6 0,000 0,04247869 0,16337958 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04247869 0,16310683 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04247869 0,16283498 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04247869 0,16256404 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04247869 0,162294 ! histidine metabolic process GO:0006547 6 6 0,000 0,04247869 0,16202486 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04247869 0,16175661 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04247869 0,16148924 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04247869 0,16122276 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04247869 0,16095715 ! adenohypophysis development GO:0021984 10 6 0,000 0,04247869 0,16069242 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04247869 0,16042856 ! hyperosmotic response GO:0006972 8 6 0,000 0,04247869 0,16016556 ! microtubule nucleation GO:0007020 10 6 0,000 0,04247869 0,15990342 ! ER overload response GO:0006983 7 6 0,000 0,04247869 0,15964214 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04247869 0,15938171 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04247869 0,15912213 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04247869 0,1588634 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04247869 0,1586055 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04247869 0,15834844 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,04247869 0,15809222 ! response to dietary excess GO:0002021 7 6 0,000 0,04247869 0,15783682 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04247869 0,15758224 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04247869 0,15732849 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04247869 0,15707555 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04247869 0,15682342 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04247869 0,1565721 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04247869 0,15632158 ! neuron apoptosis GO:0051402 8 6 0,000 0,04247869 0,15607187 ! organic alcohol transport GO:0015850 9 6 0,000 0,04247869 0,15582295 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04247869 0,15557482 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04247869 0,15532749 ! male sex determination GO:0030238 9 6 0,000 0,04247869 0,15508094 ! carnitine transport GO:0015879 8 6 0,000 0,04247869 0,15483517 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04247869 0,15459017 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04247869 0,15434596 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04247869 0,15410251 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04247869 0,15385983 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04247869 0,15361791 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04247869 0,15337675 ! parturition GO:0007567 12 6 0,000 0,04247869 0,15313635 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04247869 0,1528967 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04247869 0,1526578 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04247869 0,15241964 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04247869 0,15218223 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04247869 0,15194555 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04247869 0,15170961 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04247869 0,1514744 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04247869 0,15123992 ! macrophage differentiation GO:0030225 10 6 0,000 0,04247869 0,15100617 ! astrocyte development GO:0014002 14 6 0,000 0,04247869 0,15077313 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04247869 0,15054082 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04247869 0,15030922 ! interaction with symbiont GO:0051702 8 6 0,000 0,04247869 0,15007833 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04247869 0,14984814 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04247869 0,14961867 ! eating behavior GO:0042755 6 6 0,000 0,04247869 0,14938989 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04247869 0,14916182 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04247869 0,14893444 ! response to copper ion GO:0046688 9 6 0,000 0,04247869 0,14870775 ! DNA topological change GO:0006265 8 6 0,000 0,04247869 0,14848175 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04247869 0,14825643 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,04247869 0,1480318 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04247869 0,14780785 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04247869 0,14758458 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04247869 0,14736198 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04247869 0,14714005 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04247869 0,14691878 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04247869 0,14669818 ! gas homeostasis GO:0033483 11 6 0,000 0,04247869 0,14647825 ! hair follicle maturation GO:0048820 7 6 0,000 0,04247869 0,14625897 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04247869 0,14604034 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04247869 0,14582237 ! Schwann cell development GO:0014044 14 6 0,000 0,04247869 0,14560505 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04247869 0,14538838 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04247869 0,14517235 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04247869 0,14495696 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04247869 0,14474221 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,04247869 0,14452809 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04247869 0,14431461 ! histone ubiquitination GO:0016574 7 6 0,000 0,04247869 0,14410176 ! regulation of meiosis GO:0040020 10 6 0,000 0,04247869 0,14388953 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04247869 0,14367793 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04247869 0,14346695 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04247869 0,14325658 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04247869 0,14304684 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04247869 0,1428377 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04247869 0,14262918 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04247869 0,14242127 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04247869 0,14221396 ! receptor internalization GO:0031623 9 6 0,000 0,04247869 0,14200725 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04247869 0,14180115 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04247869 0,14159564 ! protein deubiquitination GO:0016579 8 6 0,000 0,04247869 0,14139072 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04247869 0,1411864 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04247869 0,14098267 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04247869 0,14077952 ! axonal fasciculation GO:0007413 9 6 0,000 0,04247869 0,14057696 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04247869 0,14037499 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04247869 0,14017359 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04247869 0,13997277 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04247869 0,13977252 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04247869 0,13957284 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04247869 0,13937374 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04247869 0,1391752 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04247869 0,13897723 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04247869 0,13877982 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04247869 0,13858296 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04247869 0,13838667 ! adult feeding behavior GO:0008343 6 6 0,000 0,04247869 0,13819093 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04247869 0,13799575 ! blastocyst growth GO:0001832 15 6 0,000 0,04247869 0,13780111 ! pigment granule transport GO:0051904 12 6 0,000 0,04247869 0,13760703 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04247869 0,13741349 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04247869 0,13722049 ! catecholamine transport GO:0051937 7 6 0,000 0,04247869 0,13702804 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04247869 0,13683612 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04247869 0,13664474 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04247869 0,1364539 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,04247869 0,13626358 ! protein prenylation GO:0018342 10 6 0,000 0,04247869 0,1360738 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04247869 0,13588455 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04247869 0,13569582 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04247869 0,13550761 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04247869 0,13531993 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04247869 0,13513277 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,04340833 0,13789938 ! regulation of ossification GO:0030278 71 46 1,000 0,04340833 0,13770917 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,04512851 0,1429691 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,04512851 0,14277245 ! regulation of protein polymerization GO:0032271 71 47 1,000 0,04512851 0,14257633 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,04687359 0,14788649 GO:0010952|positive regulation of peptidase activity, ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,04687359 0,1476839 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,04687359 0,14748187 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,04687359 0,14728039 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 1,000 0,04864312 0,15263188 ! maintenance of location GO:0051235 84 49 1,000 0,04864312 0,15242394 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,04938231 0,15452969 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,04938231 0,15431973 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,04938231 0,15411034 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,04938231 0,15390152 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,04938231 0,15369326 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,04938231 0,15348557 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04938231 0,15327843 GO:0070193|synaptonemal complex organization, ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04938231 0,15307186 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,04938231 0,15286584 ! reproductive behavior GO:0019098 12 7 0,000 0,04938231 0,15266037 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,04938231 0,15245546 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,04938231 0,1522511 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,04938231 0,15204728 ! oligopeptide transport GO:0006857 11 7 0,000 0,04938231 0,15184401 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,04938231 0,15164128 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,04938231 0,15143909 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,04938231 0,15123744 ! RNA methylation GO:0001510 11 7 0,000 0,04938231 0,15103633 ! pericardium development GO:0060039 8 7 0,000 0,04938231 0,15083575 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,04938231 0,1506357 ! fibril organization GO:0043206 13 7 0,000 0,04938231 0,15043618 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04938231 0,15023719 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,04938231 0,15003873 ! lipoprotein transport GO:0042953 9 7 0,000 0,04938231 0,14984079 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,04938231 0,14964337 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04938231 0,14944647 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04938231 0,14925009 ! estrogen metabolic process GO:0008210 14 7 0,000 0,04938231 0,14905422 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,04938231 0,14885887 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,04938231 0,14866403 ! chemosensory behavior GO:0007635 9 7 0,000 0,04938231 0,1484697 ! microtubule bundle formation GO:0001578 8 7 0,000 0,04938231 0,14827587 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,04938231 0,14808255 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,04938231 0,14788974 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,04938231 0,14769742 ! leukocyte degranulation GO:0043299 10 7 0,000 0,04938231 0,14750561 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,04938231 0,14731429 ! reflex GO:0060004 12 7 0,000 0,04938231 0,14712347 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04938231 0,14693314 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,04938231 0,14674331 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04938231 0,14655396 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,04938231 0,1463651 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,04938231 0,14617673 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04938231 0,14598884 ! spinal cord patterning GO:0021511 7 7 0,000 0,04938231 0,14580144 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,04938231 0,14561451 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,04938231 0,14542807 ! adrenal gland development GO:0030325 17 7 0,000 0,04938231 0,1452421 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,04938231 0,1450566 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,04938231 0,14487158 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,04938231 0,14468703 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,04938231 0,14450295 ! endosome organization GO:0007032 10 7 0,000 0,04938231 0,14431934 ! thyroid hormone generation GO:0006590 11 7 0,000 0,04938231 0,14413619 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,04938231 0,14395351 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,04938231 0,14377129 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,04938231 0,14358953 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04938231 0,14340823 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,04938231 0,14322739 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04938231 0,143047 ! galactose metabolic process GO:0006012 10 7 0,000 0,04938231 0,14286707 ! vesicle fusion GO:0006906 15 7 0,000 0,04938231 0,14268759 ! intracellular pH reduction GO:0051452 10 7 0,000 0,04938231 0,14250856 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,04938231 0,14232997 ! organ growth GO:0035265 11 7 0,000 0,04938231 0,14215184 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,04938231 0,14197415 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,04938231 0,1417969 ! retinol metabolic process GO:0042572 9 7 0,000 0,04938231 0,1416201 ! behavioral fear response GO:0001662 13 7 0,000 0,04938231 0,14144373 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,04938231 0,14126781 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,04938231 0,14109232 ! rRNA modification GO:0000154 12 7 0,000 0,04938231 0,14091727 ! protein heterooligomerization GO:0051291 10 7 0,000 0,04938231 0,14074265 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04938231 0,14056846 ! response to UV-B GO:0010224 11 7 0,000 0,04938231 0,14039471 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,04938231 0,14022138 ! intermediate filament organization GO:0045109 11 7 0,000 0,04938231 0,14004848 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,04938231 0,13987601 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,04938231 0,13970396 ! fibrinolysis GO:0042730 9 7 0,000 0,04938231 0,13953233 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,04938231 0,13936113 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,04938231 0,13919034 ! B cell lineage commitment GO:0002326 17 7 0,000 0,04938231 0,13901997 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,04938231 0,13885002 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,04938231 0,13868049 ! response to tropane GO:0014073 13 7 0,000 0,04938231 0,13851136 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,04938231 0,13834265 ! melanosome localization GO:0032400 10 7 0,000 0,04938231 0,13817435 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,04938231 0,13800646 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,04938231 0,13783898 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,04938231 0,1376719 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,04938231 0,13750523 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,04938231 0,13733896 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,04938231 0,13717309 ! mast cell activation GO:0045576 9 7 0,000 0,04938231 0,13700762 ! multicellular organismal aging GO:0010259 11 7 0,000 0,04938231 0,13684255 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,04938231 0,13667788 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,04938231 0,1365136 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,04938231 0,13634972 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,04938231 0,13618623 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,04938231 0,13602314 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,04938231 0,13586043 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,04938231 0,13569811 ! T cell lineage commitment GO:0002360 12 7 0,000 0,04938231 0,13553618 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,04938231 0,13537464 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,04938231 0,13521347 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,04938231 0,1350527 ! regulation of lipid transport GO:0032368 13 7 0,000 0,04938231 0,1348923 ! response to tumor cell GO:0002347 12 7 0,000 0,04938231 0,13473229 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,04938231 0,13457265 ! neuroblast proliferation GO:0007405 13 7 0,000 0,04938231 0,1344134 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,04938231 0,13425451 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,04938231 0,13409601 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,04938231 0,13393788 ! diuresis GO:0030146 12 7 0,000 0,04938231 0,13378012 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,04938231 0,13362273 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04938231 0,13346571 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,04938231 0,13330906 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04938231 0,13315278 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04938231 0,13299686 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04938231 0,13284131 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,04938231 0,13268612 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,04938231 0,13253129 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,04938231 0,13237683 ! lymph node development GO:0048535 9 7 0,000 0,04938231 0,13222272 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,04938231 0,13206898 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,04938231 0,13191559 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04938231 0,13176255 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,04938231 0,13160987 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,04938231 0,13145755 ! ATP catabolic process GO:0006200 10 7 0,000 0,04938231 0,13130557 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,04938231 0,13115395 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,04938231 0,13100267 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,04938231 0,13085175 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,04938231 0,13070117 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,04938231 0,13055094 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,04938231 0,13040106 ! muscle adaptation GO:0043500 12 7 0,000 0,04938231 0,13025151 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,04938231 0,13010231 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,04938231 0,12995345 ! retina homeostasis GO:0001895 9 7 0,000 0,04938231 0,12980494 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,04938231 0,12965676 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,04938231 0,12950892 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,04938231 0,12936141 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,04938231 0,12921424 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,04938231 0,12906741 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04938231 0,12892091 ! regulation of actin filament length GO:0030832 72 50 1,000 0,05043667 0,13152418 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,05043667 0,13137523 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,05043667 0,13122662 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,05043667 0,13107834 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 1,000 0,05043667 0,13093039 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,0522538 0,13549463 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,0522538 0,13534204 ! adult behavior GO:0030534 80 51 1,000 0,0522538 0,1351898 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,0522538 0,1350379 ! establishment of organelle localization GO:0051656 85 52 1,000 0,05409409 0,13963681 ! regulation of cellular component size GO:0032535 74 52 1,000 0,05409409 0,13948027 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,05409409 0,13932408 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,05595711 0,14396125 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,05595711 0,1438004 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05623655 0,14435722 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05623655 0,14419629 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,05623655 0,14403571 ! axon extension GO:0048675 11 8 0,000 0,05623655 0,14387549 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,05623655 0,14371563 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05623655 0,14355613 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05623655 0,14339697 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05623655 0,14323817 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05623655 0,14307972 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05623655 0,14292162 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,05623655 0,14276387 ! phosphate transport GO:0006817 10 8 0,000 0,05623655 0,14260647 ! N-glycan processing GO:0006491 12 8 0,000 0,05623655 0,14244942 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,05623655 0,14229271 ! UTP metabolic process GO:0046051 8 8 0,000 0,05623655 0,14213634 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05623655 0,14198032 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05623655 0,14182464 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,05623655 0,1416693 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05623655 0,1415143 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05623655 0,14135964 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05623655 0,14120532 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,05623655 0,14105133 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,05623655 0,14089768 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,05623655 0,14074436 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05623655 0,14059138 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,05623655 0,14043873 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05623655 0,14028641 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05623655 0,14013442 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05623655 0,13998276 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,05623655 0,13983143 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05623655 0,13968042 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05623655 0,13952974 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05623655 0,13937938 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05623655 0,13922935 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05623655 0,13907964 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05623655 0,13893026 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,05623655 0,13878119 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05623655 0,13863244 ! melanin metabolic process GO:0006582 12 8 0,000 0,05623655 0,13848401 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05623655 0,1383359 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05623655 0,13818811 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,05623655 0,13804063 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05623655 0,13789346 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05623655 0,13774661 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,05623655 0,13760007 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,05623655 0,13745385 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05623655 0,13730793 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,05623655 0,13716232 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05623655 0,13701702 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05623655 0,13687203 ! ruffle organization GO:0031529 11 8 0,000 0,05623655 0,13672735 ! osteoblast development GO:0002076 13 8 0,000 0,05623655 0,13658297 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05623655 0,13643889 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,05623655 0,13629512 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05623655 0,13615165 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,05623655 0,13600848 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,05623655 0,13586562 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,05623655 0,13572305 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05623655 0,13558078 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05623655 0,13543882 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05623655 0,13529714 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,05623655 0,13515577 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,05623655 0,13501469 ! oligodendrocyte development GO:0014003 8 8 0,000 0,05623655 0,1348739 ! segment specification GO:0007379 10 8 0,000 0,05623655 0,13473341 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,05623655 0,1345932 ! cellular extravasation GO:0045123 11 8 0,000 0,05623655 0,13445329 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05623655 0,13431367 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05623655 0,13417435 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05623655 0,1340353 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,05623655 0,13389655 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05623655 0,13375809 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,05623655 0,13361991 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,05623655 0,13348201 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,05623655 0,1333444 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,05623655 0,13320707 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05623655 0,13307003 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05623655 0,13293327 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,05623655 0,13279679 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05623655 0,13266058 ! icosanoid secretion GO:0032309 12 8 0,000 0,05623655 0,13252466 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,05623655 0,13238902 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05623655 0,13225365 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05623655 0,13211856 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05623655 0,13198374 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05623655 0,1318492 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05623655 0,13171494 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,05623655 0,13158094 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05623655 0,13144722 ! sterol catabolic process GO:0016127 9 8 0,000 0,05623655 0,13131378 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05623655 0,1311806 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,05623655 0,13104769 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05623655 0,13091505 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,05623655 0,13078268 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05623655 0,13065057 ! prophase GO:0051324 11 8 0,000 0,05623655 0,13051874 ! S phase GO:0051320 8 8 0,000 0,05623655 0,13038717 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,05623655 0,13025586 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,05623655 0,13012482 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05623655 0,12999404 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05623655 0,12986352 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05623655 0,12973327 ! hormone catabolic process GO:0042447 13 8 0,000 0,05623655 0,12960328 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05623655 0,12947354 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,05623655 0,12934407 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05623655 0,12921485 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05623655 0,1290859 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05623655 0,1289572 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,05623655 0,12882875 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05623655 0,12870057 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05623655 0,12857263 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05623655 0,12844495 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05623655 0,12831753 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05623655 0,12819036 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05623655 0,12806343 ! regulation of embryonic development GO:0045995 16 8 0,000 0,05623655 0,12793676 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05623655 0,12781034 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,05623655 0,12768417 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,05623655 0,12755825 ! amino acid transport GO:0006865 84 54 1,000 0,05784245 0,13107157 ! regulation of protein complex assembly GO:0043254 81 54 1,000 0,05784245 0,13094256 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,05784245 0,13081381 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,05784245 0,13068531 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,05784245 0,13055706 ! nucleoside metabolic process GO:0009116 69 55 1,000 0,0597497 0,13472972 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,06167845 0,13894263 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,06167845 0,13880668 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 0,06167845 0,13867099 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,06304176 0,1415977 ! regulation of developmental growth GO:0048638 13 9 0,000 0,06304176 0,14145956 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,06304176 0,14132168 ! telencephalon cell migration GO:0022029 16 9 0,000 0,06304176 0,14118408 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,06304176 0,14104674 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,06304176 0,14090967 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,06304176 0,14077286 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,06304176 0,14063632 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06304176 0,14050004 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,06304176 0,14036403 ! GTP metabolic process GO:0046039 9 9 0,000 0,06304176 0,14022828 ! elastic fiber assembly GO:0048251 13 9 0,000 0,06304176 0,1400928 ! social behavior GO:0035176 14 9 0,000 0,06304176 0,13995757 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,06304176 0,13982261 ! regulation of histone modification GO:0031056 11 9 0,000 0,06304176 0,13968791 ! regulation of glycolysis GO:0006110 15 9 0,000 0,06304176 0,13955346 ! response to pain GO:0048265 16 9 0,000 0,06304176 0,13941927 ! protein complex disassembly GO:0043241 17 9 0,000 0,06304176 0,13928535 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,06304176 0,13915168 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,06304176 0,13901826 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,06304176 0,1388851 ! lung alveolus development GO:0048286 17 9 0,000 0,06304176 0,1387522 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,06304176 0,13861955 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,06304176 0,13848715 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,06304176 0,13835501 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,06304176 0,13822311 ! ventral spinal cord development GO:0021517 11 9 0,000 0,06304176 0,13809147 ! protein targeting to ER GO:0045047 19 9 0,000 0,06304176 0,13796008 ! T cell selection GO:0045058 18 9 0,000 0,06304176 0,13782894 ! endoderm development GO:0007492 12 9 0,000 0,06304176 0,13769805 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,06304176 0,13756741 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,06304176 0,13743701 ! arginine catabolic process GO:0006527 10 9 0,000 0,06304176 0,13730686 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,06304176 0,13717696 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,06304176 0,1370473 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,06304176 0,13691789 ! V(D)J recombination GO:0033151 12 9 0,000 0,06304176 0,13678872 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,06304176 0,1366598 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,06304176 0,13653112 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,06304176 0,13640268 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06304176 0,13627448 ! mannose metabolic process GO:0006013 9 9 0,000 0,06304176 0,13614652 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,06304176 0,1360188 ! receptor clustering GO:0043113 15 9 0,000 0,06304176 0,13589133 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,06304176 0,13576409 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,06304176 0,13563709 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,06304176 0,13551032 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,06304176 0,1353838 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,06304176 0,13525751 ! motor axon guidance GO:0008045 14 9 0,000 0,06304176 0,13513145 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,06304176 0,13500563 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,06304176 0,13488004 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,06304176 0,13475469 ! blastoderm segmentation GO:0007350 11 9 0,000 0,06304176 0,13462957 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,06304176 0,13450468 ! DNA ligation GO:0006266 14 9 0,000 0,06304176 0,13438002 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,06304176 0,1342556 ! response to amine stimulus GO:0014075 13 9 0,000 0,06304176 0,1341314 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,06304176 0,13400744 ! erythrocyte development GO:0048821 11 9 0,000 0,06304176 0,1338837 ! renal water homeostasis GO:0003091 14 9 0,000 0,06304176 0,13376019 ! postreplication repair GO:0006301 11 9 0,000 0,06304176 0,13363691 ! mRNA cleavage GO:0006379 13 9 0,000 0,06304176 0,13351385 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,06304176 0,13339103 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,06304176 0,13326842 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,06304176 0,13314605 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,06304176 0,1330239 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,06304176 0,13290197 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,06304176 0,13278026 ! acid secretion GO:0046717 14 9 0,000 0,06304176 0,13265878 ! musculoskeletal movement GO:0050881 11 9 0,000 0,06304176 0,13253752 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,06304176 0,13241648 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,06304176 0,13229566 ! purine base metabolic process GO:0006144 18 9 0,000 0,06304176 0,13217506 ! oocyte differentiation GO:0009994 12 9 0,000 0,06304176 0,13205469 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,06304176 0,13193453 ! spleen development GO:0048536 15 9 0,000 0,06304176 0,13181459 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,06304176 0,13169486 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,06304176 0,13157536 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,06304176 0,13145607 ! detection of calcium ion GO:0005513 13 9 0,000 0,06304176 0,131337 ! blastocyst formation GO:0001825 12 9 0,000 0,06304176 0,13121814 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,06304176 0,1310995 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,06304176 0,13098107 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,06304176 0,13086286 ! prepulse inhibition GO:0060134 14 9 0,000 0,06304176 0,13074486 ! embryonic placenta development GO:0001892 12 9 0,000 0,06304176 0,13062707 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,06304176 0,13050949 ! insulin secretion GO:0030073 17 9 0,000 0,06304176 0,13039213 ! sequestering of metal ion GO:0051238 11 9 0,000 0,06304176 0,13027497 ! establishment of cell polarity GO:0030010 12 9 0,000 0,06304176 0,13015803 ! nucleus localization GO:0051647 15 9 0,000 0,06304176 0,1300413 ! regulation of synapse organization GO:0050807 12 9 0,000 0,06304176 0,12992477 ! localization within membrane GO:0051668 15 9 0,000 0,06304176 0,12980846 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,06362829 0,13089898 ! developmental maturation GO:0021700 75 57 1,000 0,06362829 0,130782 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,06362829 0,13066523 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,06559882 0,13459169 ! viral reproductive process GO:0022415 87 58 1,000 0,06559882 0,13447174 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,06559882 0,13435199 ! activation of MAPK activity GO:0000187 84 59 1,000 0,06758966 0,13830624 ! lung development GO:0030324 94 59 1,000 0,06758966 0,1381833 ! actin filament organization GO:0007015 95 59 1,000 0,06758966 0,13806058 ! nucleoside monophosphate metabolic process GO:0009123 95 59 1,000 0,06758966 0,13793807 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,06758966 0,13781579 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,0696004 0,14179002 GO:0035113|embryonic appendage morphogenesis, ! regulation of heart contraction GO:0008016 91 60 1,000 0,0696004 0,14166454 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,06979828 0,14194169 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,06979828 0,1418163 ! neuron fate specification GO:0048665 11 10 0,000 0,06979828 0,14169113 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,06979828 0,14156618 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,06979828 0,14144145 ! thyroid gland development GO:0030878 19 10 0,000 0,06979828 0,14131695 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,06979828 0,14119266 ! synapsis GO:0007129 13 10 0,000 0,06979828 0,14106859 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,06979828 0,14094473 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,06979828 0,1408211 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,06979828 0,14069768 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,06979828 0,14057447 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,06979828 0,14045149 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,06979828 0,14032872 ! androgen metabolic process GO:0008209 13 10 0,000 0,06979828 0,14020616 ! phospholipid efflux GO:0033700 16 10 0,000 0,06979828 0,14008381 ! hippocampus development GO:0021766 19 10 0,000 0,06979828 0,13996168 ! blood vessel remodeling GO:0001974 21 10 0,000 0,06979828 0,13983977 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,06979828 0,13971806 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,06979828 0,13959657 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,06979828 0,13947528 ! pathogenesis GO:0009405 13 10 0,000 0,06979828 0,13935421 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,06979828 0,13923335 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06979828 0,1391127 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,06979828 0,13899225 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,06979828 0,13887202 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,06979828 0,13875199 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,06979828 0,13863217 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,06979828 0,13851255 ! melanocyte differentiation GO:0030318 15 10 0,000 0,06979828 0,13839315 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,06979828 0,13827395 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,06979828 0,13815495 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06979828 0,13803616 ! response to X-ray GO:0010165 16 10 0,000 0,06979828 0,13791757 ! B cell proliferation GO:0042100 14 10 0,000 0,06979828 0,13779918 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,06979828 0,137681 ! forebrain cell migration GO:0021885 17 10 0,000 0,06979828 0,13756303 ! lipid digestion GO:0044241 15 10 0,000 0,06979828 0,13744525 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,06979828 0,13732767 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,06979828 0,1372103 ! UV protection GO:0009650 14 10 0,000 0,06979828 0,13709313 ! entry into host cell GO:0030260 20 10 0,000 0,06979828 0,13697615 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,06979828 0,13685938 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,06979828 0,1367428 ! negative regulation of ossification GO:0030279 19 10 0,000 0,06979828 0,13662643 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,06979828 0,13651025 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,06979828 0,13639427 ! regulation of bone resorption GO:0045124 24 10 0,000 0,06979828 0,13627848 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,06979828 0,13616289 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,06979828 0,1360475 ! regulation of organ growth GO:0046620 11 10 0,000 0,06979828 0,1359323 ! response to dsRNA GO:0043331 18 10 0,000 0,06979828 0,1358173 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,06979828 0,13570249 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06979828 0,13558788 ! embryonic axis specification GO:0000578 12 10 0,000 0,06979828 0,13547346 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,06979828 0,13535923 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,06979828 0,1352452 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,06979828 0,13513136 ! cranial nerve development GO:0021545 12 10 0,000 0,06979828 0,1350177 ! fucose catabolic process GO:0019317 16 10 0,000 0,06979828 0,13490424 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,06979828 0,13479097 ! protein sumoylation GO:0016925 12 10 0,000 0,06979828 0,13467789 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,06979828 0,134565 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06979828 0,1344523 ! zymogen activation GO:0031638 14 10 0,000 0,06979828 0,13433979 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06979828 0,13422747 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,06979828 0,13411533 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,06979828 0,13400338 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,06979828 0,13389162 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,06979828 0,13378004 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,06979828 0,13366865 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06979828 0,13355745 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,06979828 0,13344643 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,06979828 0,13333559 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,06979828 0,13322494 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,06979828 0,13311447 ! embryonic gut development GO:0048566 11 10 0,000 0,06979828 0,13300418 ! activation of innate immune response GO:0002218 10 10 0,000 0,06979828 0,13289408 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,06979828 0,13278416 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,06979828 0,13267442 ! developmental induction GO:0031128 13 10 0,000 0,06979828 0,13256486 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,06979828 0,13245549 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,06979828 0,13234629 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,06979828 0,13223727 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,06979828 0,13212844 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,07163068 0,13548566 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,07163068 0,13537433 ! urogenital system development GO:0001655 101 61 1,000 0,07163068 0,13526318 ! homeostasis of number of cells GO:0048872 84 61 1,000 0,07163068 0,13515222 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,07163068 0,13504144 ! respiratory tube development GO:0030323 99 62 1,000 0,0736801 0,13879134 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,0736801 0,13867776 ! organelle localization GO:0051640 96 62 1,000 0,0736801 0,13856437 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,07574829 0,14233747 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,07574829 0,14222127 ! viral reproduction GO:0016032 92 63 1,000 0,07574829 0,14210527 ! regulation of lipase activity GO:0060191 109 63 1,000 0,07574829 0,14198945 ! rRNA transcription GO:0009303 17 11 0,000 0,07650647 0,14329387 ! respiratory burst GO:0045730 14 11 0,000 0,07650647 0,14317728 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07650647 0,14306088 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07650647 0,14294466 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,07650647 0,14282863 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,07650647 0,1427128 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,07650647 0,14259715 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,07650647 0,14248168 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07650647 0,14236641 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07650647 0,14225132 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,07650647 0,14213641 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,07650647 0,14202169 ! mating GO:0007618 14 11 0,000 0,07650647 0,14190716 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,07650647 0,14179281 ! T cell proliferation GO:0042098 20 11 0,000 0,07650647 0,14167864 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,07650647 0,14156466 ! bone resorption GO:0045453 16 11 0,000 0,07650647 0,14145087 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07650647 0,14133725 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07650647 0,14122382 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,07650647 0,14111057 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,07650647 0,1409975 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07650647 0,14088461 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,07650647 0,1407719 ! syncytium formation GO:0006949 15 11 0,000 0,07650647 0,14065937 ! plasma membrane organization GO:0007009 18 11 0,000 0,07650647 0,14054703 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,07650647 0,14043486 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,07650647 0,14032287 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,07650647 0,14021106 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07650647 0,14009942 ! adult heart development GO:0007512 11 11 0,000 0,07650647 0,13998797 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,07650647 0,13987669 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,07650647 0,13976559 ! temperature homeostasis GO:0001659 16 11 0,000 0,07650647 0,13965466 ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,07650647 0,13954392 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07650647 0,13943334 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07650647 0,13932294 ! stem cell development GO:0048864 29 11 0,000 0,07650647 0,13921272 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,07650647 0,13910267 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07650647 0,13899279 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,07650647 0,13888309 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07650647 0,13877356 ! vasoconstriction GO:0042310 15 11 0,000 0,07650647 0,13866421 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,07650647 0,13855502 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,07650647 0,13844601 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07650647 0,13833717 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07650647 0,1382285 ! ribosome assembly GO:0042255 13 11 0,000 0,07650647 0,13812 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,07650647 0,13801167 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,07650647 0,13790351 ! chromatin silencing GO:0006342 19 11 0,000 0,07650647 0,13779552 ! nucleosome positioning GO:0016584 13 11 0,000 0,07650647 0,1376877 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07650647 0,13758004 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,07650647 0,13747256 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07650647 0,13736524 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07650647 0,13725809 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,07650647 0,13715111 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,07650647 0,1370443 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,07650647 0,13693765 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,07650647 0,13683116 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,07650647 0,13672485 ! male genitalia development GO:0030539 13 11 0,000 0,07650647 0,13661869 ! cholesterol efflux GO:0033344 19 11 0,000 0,07650647 0,13651271 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,07650647 0,13640688 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07650647 0,13630122 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,07650647 0,13619573 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,07650647 0,13609039 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,07650647 0,13598522 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,07650647 0,13588021 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07650647 0,13577537 ! lysogeny GO:0030069 18 11 0,000 0,07650647 0,13567068 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07650647 0,13556616 ! acrosome reaction GO:0007340 13 11 0,000 0,07650647 0,1354618 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07650647 0,1353576 ! appendage morphogenesis GO:0035107 93 64 1,000 0,07783487 0,137602 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,07783487 0,13749632 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,07783487 0,1373908 ! respiratory system development GO:0060541 100 64 1,000 0,07783487 0,13728543 ! reproductive structure development GO:0048608 90 65 1,000 0,07993949 0,14088952 ! appendage development GO:0048736 94 65 1,000 0,07993949 0,14078164 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 1,000 0,07993949 0,14067393 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,07993949 0,14056638 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,07993949 0,140459 ! protein oligomerization GO:0051259 100 65 1,000 0,07993949 0,14035178 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,08206177 0,14396802 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,08206177 0,14385829 ! regulation of immune effector process GO:0002697 101 66 1,000 0,08206177 0,14374873 ! lactation GO:0007595 20 12 0,000 0,08316666 0,1455733 ! reproductive cellular process GO:0048610 14 12 0,000 0,08316666 0,1454626 ! tRNA modification GO:0006400 14 12 0,000 0,08316666 0,14535206 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,08316666 0,1452417 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,08316666 0,1451315 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,08316666 0,14502147 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,08316666 0,1449116 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,08316666 0,1448019 ! non-recombinational repair GO:0000726 19 12 0,000 0,08316666 0,14469237 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,08316666 0,144583 ! peroxisomal transport GO:0043574 21 12 0,000 0,08316666 0,1444738 ! cartilage condensation GO:0001502 18 12 0,000 0,08316666 0,14436477 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,08316666 0,14425589 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,08316666 0,14414719 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,08316666 0,14403864 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,08316666 0,14393026 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,08316666 0,14382204 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,08316666 0,14371399 ! arginine metabolic process GO:0006525 13 12 0,000 0,08316666 0,14360609 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,08316666 0,14349836 ! methionine metabolic process GO:0006555 13 12 0,000 0,08316666 0,14339079 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,08316666 0,14328338 ! Golgi organization GO:0007030 18 12 0,000 0,08316666 0,14317613 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,08316666 0,14306905 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,08316666 0,14296212 ! monoamine transport GO:0015844 13 12 0,000 0,08316666 0,14285535 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08316666 0,14274874 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,08316666 0,14264229 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,08316666 0,142536 ! L-amino acid transport GO:0015807 20 12 0,000 0,08316666 0,14242987 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,08316666 0,14232389 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,08316666 0,14221808 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,08316666 0,14211242 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08316666 0,14200692 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,08316666 0,14190157 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,08316666 0,14179638 ! cerebellum development GO:0021549 13 12 0,000 0,08316666 0,14169134 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,08316666 0,14158647 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,08316666 0,14148174 ! histone acetylation GO:0016573 23 12 0,000 0,08316666 0,14137717 ! histone methylation GO:0016571 15 12 0,000 0,08316666 0,14127276 ! autonomic nervous system development GO:0048483 23 12 0,000 0,08316666 0,1411685 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,08316666 0,14106439 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,08316666 0,14096044 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,08316666 0,14085664 ! response to gamma radiation GO:0010332 20 12 0,000 0,08316666 0,14075299 ! intestinal absorption GO:0050892 19 12 0,000 0,08316666 0,1406495 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,08316666 0,14054615 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,08316666 0,14044296 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,08316666 0,14033992 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,08316666 0,14023703 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,08316666 0,1401343 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,08316666 0,14003171 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,08316666 0,13992927 ! microspike assembly GO:0030035 23 12 0,000 0,08316666 0,13982698 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,08316666 0,13972485 ! response to cold GO:0009409 14 12 0,000 0,08316666 0,13962286 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,08977919 0,15061426 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,08977919 0,15050448 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,08977919 0,15039486 ! cGMP metabolic process GO:0046068 16 13 0,000 0,08977919 0,15028541 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,08977919 0,15017611 ! water transport GO:0006833 17 13 0,000 0,08977919 0,15006697 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,08977919 0,14995799 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,08977919 0,14984916 ! lipid localization GO:0010876 24 13 0,000 0,08977919 0,1497405 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,08977919 0,14963199 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,08977919 0,14952364 ! organelle fusion GO:0048284 28 13 0,000 0,08977919 0,14941545 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,08977919 0,14930741 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,08977919 0,14919953 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,08977919 0,1490918 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,08977919 0,14898423 ! response to hexose stimulus GO:0009746 19 13 0,000 0,08977919 0,14887682 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,08977919 0,14876956 ! glutamate metabolic process GO:0006536 18 13 0,000 0,08977919 0,14866245 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,08977919 0,1485555 ! cytokine metabolic process GO:0042107 17 13 0,000 0,08977919 0,1484487 ! NAD metabolic process GO:0019674 21 13 0,000 0,08977919 0,14834206 ! bone mineralization GO:0030282 15 13 0,000 0,08977919 0,14823557 ! regulation of exocytosis GO:0017157 17 13 0,000 0,08977919 0,14812923 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,08977919 0,14802304 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,08977919 0,14791701 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,08977919 0,14781113 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,08977919 0,1477054 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,08977919 0,14759982 ! genitalia development GO:0048806 15 13 0,000 0,08977919 0,14749439 ! regulation of cellular pH GO:0030641 20 13 0,000 0,08977919 0,14738911 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,08977919 0,14728399 ! tissue regeneration GO:0042246 21 13 0,000 0,08977919 0,14717901 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,08977919 0,14707418 ! cofactor transport GO:0051181 19 13 0,000 0,08977919 0,1469695 ! NADP metabolic process GO:0006739 18 13 0,000 0,08977919 0,14686497 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,08977919 0,14676059 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,08977919 0,14665635 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08977919 0,14655227 ! gas transport GO:0015669 18 13 0,000 0,08977919 0,14644833 ! regulation of RNA stability GO:0043487 28 13 0,000 0,08977919 0,14634454 ! heme biosynthetic process GO:0006783 20 13 0,000 0,08977919 0,1462409 ! regulation of axon extension GO:0030516 23 13 0,000 0,08977919 0,1461374 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,08977919 0,14603405 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,08977919 0,14593085 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,08977919 0,14582779 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,08977919 0,14572487 ! eye development GO:0001654 111 70 1,000 0,09072046 0,14714884 ! amine transport GO:0015837 101 70 1,000 0,09072046 0,14704514 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,09072046 0,14694158 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,09292577 0,15040765 ! muscle cell differentiation GO:0042692 104 71 1,000 0,09292577 0,15030188 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,09292577 0,15019625 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,09514666 0,15367789 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,09514666 0,15357004 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,09634441 0,15539422 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,09634441 0,15528532 ! superoxide anion generation GO:0042554 18 14 0,000 0,09634441 0,15517658 ! neuron maturation GO:0042551 21 14 0,000 0,09634441 0,15506799 ! regulation of S phase GO:0033261 18 14 0,000 0,09634441 0,15495955 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09634441 0,15485126 ! myotube differentiation GO:0014902 21 14 0,000 0,09634441 0,15474312 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,09634441 0,15463514 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,09634441 0,1545273 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,09634441 0,15441962 ! inositol metabolic process GO:0006020 20 14 0,000 0,09634441 0,15431208 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09634441 0,1542047 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09634441 0,15409746 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09634441 0,15399038 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09634441 0,15388344 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09634441 0,15377665 ! response to cAMP GO:0051591 19 14 0,000 0,09634441 0,15367001 ! limbic system development GO:0021761 25 14 0,000 0,09634441 0,15356352 ! startle response GO:0001964 21 14 0,000 0,09634441 0,15345717 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09634441 0,15335097 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,09634441 0,15324492 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,09634441 0,15313901 ! glycine metabolic process GO:0006544 22 14 0,000 0,09634441 0,15303325 ! pituitary gland development GO:0021983 23 14 0,000 0,09634441 0,15292764 ! cellular response to starvation GO:0009267 21 14 0,000 0,09634441 0,15282217 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,09634441 0,15271685 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,09634441 0,15261168 ! regulation of heart rate GO:0002027 23 14 0,000 0,09634441 0,15250664 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09634441 0,15240176 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09634441 0,15229701 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,09634441 0,15219241 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,09634441 0,15208796 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,09634441 0,15198364 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,09634441 0,15187947 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,09634441 0,15177545 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,09634441 0,15167156 ! axon cargo transport GO:0008088 27 14 0,000 0,09634441 0,15156782 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09634441 0,15146422 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,09634441 0,15136076 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,09634441 0,15125744 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,09634441 0,15115426 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09634441 0,15105123 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09634441 0,15094833 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,09634441 0,15084558 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09634441 0,15074296 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,09634441 0,15064048 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09634441 0,15053815 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,09634441 0,15043595 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,09634441 0,15033389 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,09634441 0,15023197 ! muscle maintenance GO:0046716 19 14 0,000 0,09634441 0,15013018 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,09634441 0,15002854 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09634441 0,14992703 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09634441 0,14982566 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,09634441 0,14972443 ! cilium assembly GO:0042384 20 14 0,000 0,09634441 0,14962333 ! peptide hormone secretion GO:0030072 23 14 0,000 0,09634441 0,14952237 ! regulation of blood pressure GO:0008217 107 73 1,000 0,09738278 0,15103197 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,09963382 0,15441899 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,10286265 0,15931589 ! metencephalon development GO:0022037 19 15 0,000 0,10286265 0,15920868 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,10286265 0,15910162 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,10286265 0,15899469 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,10286265 0,15888791 ! lipid phosphorylation GO:0046834 23 15 0,000 0,10286265 0,15878128 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,10286265 0,15867478 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,10286265 0,15856843 ! bile acid metabolic process GO:0008206 22 15 0,000 0,10286265 0,15846223 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,10286265 0,15835616 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,10286265 0,15825024 ! adult walking behavior GO:0007628 25 15 0,000 0,10286265 0,15814445 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,10286265 0,15803881 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,10286265 0,15793331 ! centrosome cycle GO:0007098 16 15 0,000 0,10286265 0,15782795 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,10286265 0,15772274 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,10286265 0,15761766 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,10286265 0,15751272 ! cerebral cortex development GO:0021987 29 15 0,000 0,10286265 0,15740792 ! response to osmotic stress GO:0006970 22 15 0,000 0,10286265 0,15730326 ! vesicle coating GO:0006901 25 15 0,000 0,10286265 0,15719874 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,10286265 0,15709436 ! DNA integration GO:0015074 22 15 0,000 0,10286265 0,15699011 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,10286265 0,15688601 ! peptide secretion GO:0002790 27 15 0,000 0,10286265 0,15678204 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,10286265 0,15667821 ! regulation of vasodilation GO:0042312 24 15 0,000 0,10286265 0,15657452 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,10286265 0,15647097 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,10286265 0,15636755 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,10286265 0,15626427 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,10286265 0,15616112 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,10286265 0,15605812 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,10286265 0,15595524 ! biomineral formation GO:0031214 18 15 0,000 0,10286265 0,15585251 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,10286265 0,1557499 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,10286265 0,15564744 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,10286265 0,1555451 ! organic cation transport GO:0015695 19 15 0,000 0,10286265 0,15544291 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,10286265 0,15534084 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,10286265 0,15523891 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 19 15 0,000 0,10286265 0,15513712 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,10286265 0,15503545 ! amine biosynthetic process GO:0009309 97 76 1,000 0,10417932 0,15691711 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,10417932 0,15681441 ! protein ubiquitination GO:0016567 125 77 1,000 0,10647313 0,16016233 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,10647313 0,16005765 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,10647313 0,15995311 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,10647313 0,1598487 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,10878057 0,16320634 ! protein secretion GO:0009306 27 16 0,000 0,10933425 0,16393009 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,10933425 0,1638233 ! hormone secretion GO:0046879 25 16 0,000 0,10933425 0,16371664 ! bone remodeling GO:0046849 24 16 0,000 0,10933425 0,16361013 ! endothelial cell migration GO:0043542 22 16 0,000 0,10933425 0,16350375 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,10933425 0,16339751 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,10933425 0,16329141 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,10933425 0,16318544 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,10933425 0,16307961 ! glial cell development GO:0021782 24 16 0,000 0,10933425 0,16297392 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,10933425 0,16286837 GO:0042744|hydrogen peroxide catabolic process, ! protein polyubiquitination GO:0000209 26 16 0,000 0,10933425 0,16276295 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,10933425 0,16265767 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,10933425 0,16255253 GO:0030968|endoplasmic reticulum unfolded protein response, ! fructose metabolic process GO:0006000 20 16 0,000 0,10933425 0,16244752 ! regulation of protein binding GO:0043393 27 16 0,000 0,10933425 0,16234265 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,10933425 0,16223791 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,10933425 0,16213331 ! DNA replication initiation GO:0006270 25 16 0,000 0,10933425 0,16202884 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,10933425 0,16192451 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,10933425 0,16182031 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,10933425 0,16171625 ! diencephalon development GO:0021536 25 16 0,000 0,10933425 0,16161232 ! oogenesis GO:0048477 23 16 0,000 0,10933425 0,16150852 ! neural crest cell migration GO:0001755 24 16 0,000 0,10933425 0,16140486 ! G1 phase GO:0051318 27 16 0,000 0,10933425 0,16130132 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,10933425 0,16119793 GO:0006626|protein targeting to mitochondrion, ! steroid catabolic process GO:0006706 22 16 0,000 0,10933425 0,16109466 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,10933425 0,16099153 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,10933425 0,16088853 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,10933425 0,16078566 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,10933425 0,16068292 ! sperm-egg recognition GO:0035036 16 16 0,000 0,10933425 0,16058031 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,10933425 0,16047783 ! nerve development GO:0021675 18 16 0,000 0,10933425 0,16037549 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,10933425 0,16027327 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,10933425 0,16017119 ! negative regulation of translation GO:0017148 22 16 0,000 0,10933425 0,16006923 ! alcohol catabolic process GO:0046164 104 80 1,000 0,11343509 0,16596737 ! regulation of GTPase activity GO:0043087 129 80 1,000 0,11343509 0,16586186 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,11575952 0,16915305 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,11575952 0,16904565 ! negative regulation of defense response GO:0031348 19 17 0,000 0,11575952 0,16893839 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,11575952 0,16883126 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,11575952 0,16872427 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,11575952 0,16861742 ! signal complex assembly GO:0007172 29 17 0,000 0,11575952 0,1685107 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,11575952 0,16840411 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,11575952 0,16829766 ! memory GO:0007613 25 17 0,000 0,11575952 0,16819135 ! keratinization GO:0031424 17 17 0,000 0,11575952 0,16808517 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,11575952 0,16797912 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,11575952 0,1678732 ! retinoid metabolic process GO:0001523 22 17 0,000 0,11575952 0,16776742 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,11575952 0,16766178 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,11575952 0,16755626 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,11575952 0,16745088 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,11575952 0,16734563 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,11575952 0,16724052 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,11575952 0,16713553 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,11575952 0,16703068 ! membrane budding GO:0006900 29 17 0,000 0,11575952 0,16692596 ! heme metabolic process GO:0042168 27 17 0,000 0,11575952 0,16682137 ! neuromuscular junction development GO:0007528 23 17 0,000 0,11575952 0,16671691 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,11575952 0,16661258 ! body fluid secretion GO:0007589 27 17 0,000 0,11575952 0,16650838 ! stem cell differentiation GO:0048863 36 17 0,000 0,11575952 0,16640431 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,11575952 0,16630038 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,11575952 0,16619657 ! sensory perception of pain GO:0019233 23 17 0,000 0,11575952 0,16609289 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,11575952 0,16598934 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,11575952 0,16588592 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,11575952 0,16578263 ! synaptogenesis GO:0007416 24 17 0,000 0,11575952 0,16567947 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,11575952 0,16557643 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,11575952 0,16547353 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,11575952 0,16537075 ! cell-cell junction organization GO:0045216 25 17 0,000 0,11575952 0,1652681 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,11575952 0,16516557 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,11575952 0,16506318 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,11575952 0,16496091 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,11575952 0,16485876 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,11575952 0,16475675 ! regulation of neurological system process GO:0031644 122 81 1,000 0,11578155 0,16468619 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,11578155 0,1645844 GO:0002696|positive regulation of leukocyte activation, ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,12051138 0,17120208 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,12051138 0,1710964 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,12213881 0,17329998 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,12213881 0,17319314 ! positive regulation of translation GO:0045727 28 18 0,000 0,12213881 0,17308643 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,12213881 0,17297985 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,12213881 0,1728734 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,12213881 0,17276708 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,12213881 0,17266089 ! cAMP metabolic process GO:0046058 33 18 0,000 0,12213881 0,17255483 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,12213881 0,17244891 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,12213881 0,17234311 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,12213881 0,17223744 ! axis specification GO:0009798 26 18 0,000 0,12213881 0,17213191 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,12213881 0,1720265 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,12213881 0,17192122 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,12213881 0,17181607 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,12213881 0,17171104 ! glutamine metabolic process GO:0006541 23 18 0,000 0,12213881 0,17160615 ! response to retinoic acid GO:0032526 25 18 0,000 0,12213881 0,17150139 ! pigmentation during development GO:0048066 31 18 0,000 0,12213881 0,17139675 ! central nervous system neuron development GO:0021954 30 18 0,000 0,12213881 0,17129224 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,12213881 0,17118785 ! fucose metabolic process GO:0006004 26 18 0,000 0,12213881 0,1710836 ! response to fungus GO:0009620 19 18 0,000 0,12213881 0,17097947 ! peptide cross-linking GO:0018149 31 18 0,000 0,12213881 0,17087547 ! heart process GO:0003015 27 18 0,000 0,12213881 0,17077159 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,12213881 0,17066784 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 35 18 0,000 0,12213881 0,17056422 ! somitogenesis GO:0001756 24 18 0,000 0,12213881 0,17046072 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,12213881 0,17035735 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,12213881 0,1702541 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,12213881 0,17015098 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,12213881 0,17004798 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,12213881 0,16994511 ! vitamin transport GO:0051180 24 18 0,000 0,12213881 0,16984236 ! hormone transport GO:0009914 27 18 0,000 0,12213881 0,16973974 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,12213881 0,16963724 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,12213881 0,16953486 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,12213881 0,16943261 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,12213881 0,16933048 ! cell-cell recognition GO:0009988 20 18 0,000 0,12213881 0,16922848 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,12213881 0,16912659 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,12213881 0,16902483 ! regulation of glucose import GO:0046324 21 18 0,000 0,12213881 0,16892319 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,12213881 0,16882168 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,12213881 0,16872028 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,12213881 0,16861901 ! regulation of defense response GO:0031347 117 84 1,000 0,12289416 0,16956002 ! Golgi vesicle transport GO:0048193 138 85 1,000 0,12528845 0,17275986 ! rRNA metabolic process GO:0016072 107 85 1,000 0,12528845 0,17265635 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,12528845 0,17255296 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 0,12769399 0,17576072 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,12847244 0,17672645 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,12847244 0,17662081 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,12847244 0,1765153 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,12847244 0,17640992 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,12847244 0,17630466 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,12847244 0,17619953 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,12847244 0,17609453 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,12847244 0,17598965 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,12847244 0,17588489 ! sensory perception of taste GO:0050909 23 19 0,000 0,12847244 0,17578026 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,12847244 0,17567575 ! smooth muscle contraction GO:0006939 36 19 0,000 0,12847244 0,17557137 ! peroxisome organization GO:0007031 29 19 0,000 0,12847244 0,17546711 ! digestive system process GO:0022600 30 19 0,000 0,12847244 0,17536298 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,12847244 0,17525897 ! response to vitamin A GO:0033189 26 19 0,000 0,12847244 0,17515508 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,12847244 0,17505131 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,12847244 0,17494767 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,12847244 0,17484415 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,12847244 0,17474076 ! response to starvation GO:0042594 30 19 0,000 0,12847244 0,17463748 ! sex determination GO:0007530 29 19 0,000 0,12847244 0,17453433 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,12847244 0,1744313 ! plasma membrane fusion GO:0045026 23 19 0,000 0,12847244 0,17432839 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,12847244 0,1742256 ! cytolysis GO:0019835 20 19 0,000 0,12847244 0,17412293 ! renal system process GO:0003014 35 19 0,000 0,12847244 0,17402039 ! vasodilation GO:0042311 33 19 0,000 0,12847244 0,17391796 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,12847244 0,17381566 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,12847244 0,17371347 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,12847244 0,17361141 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,12847244 0,17350946 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,12847244 0,17340764 ! sarcomere organization GO:0045214 23 19 0,000 0,12847244 0,17330593 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,12847244 0,17320435 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,12847244 0,17310288 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,12847244 0,17300153 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,12847244 0,1729003 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,12847244 0,17279919 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,12847244 0,1726982 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,12847244 0,17259732 ! protein stabilization GO:0050821 26 19 0,000 0,12847244 0,17249657 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,13011047 0,17459398 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,13011047 0,17449218 ! interphase GO:0051325 159 88 1,000 0,13253763 0,17764367 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,13476074 0,18051817 ! iron ion transport GO:0006826 37 20 0,000 0,13476074 0,18041309 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,13476074 0,18030814 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,13476074 0,18020331 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,13476074 0,1800986 ! response to vitamin GO:0033273 29 20 0,000 0,13476074 0,17999401 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,13476074 0,17988955 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,13476074 0,1797852 ! spinal cord development GO:0021510 31 20 0,000 0,13476074 0,17968098 ! response to ethanol GO:0045471 37 20 0,000 0,13476074 0,17957688 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,13476074 0,1794729 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,13476074 0,17936904 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,13476074 0,17926529 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,13476074 0,17916167 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,13476074 0,17905817 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,13476074 0,17895479 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,13476074 0,17885153 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,13476074 0,17874838 ! pallium development GO:0021543 38 20 0,000 0,13476074 0,17864536 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,13476074 0,17854245 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,13476074 0,17843966 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,13476074 0,17833699 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,13476074 0,17823444 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,13476074 0,17813201 ! collagen catabolic process GO:0030574 25 20 0,000 0,13476074 0,17802969 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,13476074 0,17792749 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,13476074 0,17782541 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,13476074 0,17772345 ! actin filament-based movement GO:0030048 34 20 0,000 0,13476074 0,1776216 ! reproductive developmental process GO:0003006 127 89 1,000 0,13497518 0,17780236 ! regulation of T cell activation GO:0050863 128 89 1,000 0,13497518 0,17770058 ! leukocyte differentiation GO:0002521 143 90 1,000 0,13742286 0,18081955 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,13742286 0,18071617 ! hormone metabolic process GO:0042445 121 90 1,000 0,13742286 0,1806129 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,14100402 0,18521373 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,14100402 0,18510801 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,14100402 0,18500242 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,14100402 0,18489694 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,14100402 0,18479159 GO:0009799|determination of symmetry, ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,14100402 0,18468635 ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,14100402 0,18458124 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,14100402 0,18447624 ! protein amino acid acylation GO:0043543 37 21 0,000 0,14100402 0,18437137 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,14100402 0,18426661 ! vesicle docking GO:0048278 27 21 0,000 0,14100402 0,18416197 ! phototransduction GO:0007602 25 21 0,000 0,14100402 0,18405746 ! dendrite development GO:0016358 35 21 0,000 0,14100402 0,18395305 ! visual behavior GO:0007632 39 21 0,000 0,14100402 0,18384877 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,14100402 0,18374461 ! ovarian follicle development GO:0001541 30 21 0,000 0,14100402 0,18364056 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,14100402 0,18353664 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,14100402 0,18343283 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,14100402 0,18332913 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,14100402 0,18322556 ! cell aging GO:0007569 32 21 0,000 0,14100402 0,1831221 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,14100402 0,18301876 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,14100402 0,18291553 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,14100402 0,18281242 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,14100402 0,18270943 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,14100402 0,18260655 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,14100402 0,18250379 ! fatty acid transport GO:0015908 30 21 0,000 0,14100402 0,18240114 ! immunoglobulin production GO:0002377 33 21 0,000 0,14100402 0,18229861 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,14100402 0,1821962 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,14100402 0,1820939 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,14100402 0,18199171 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,14100402 0,18188964 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,14100402 0,18178769 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,14100402 0,18168585 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,14100402 0,18158412 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,14100402 0,1814825 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,14100402 0,181381 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,14100402 0,18127962 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,14100402 0,18117834 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,14100402 0,18107718 GO:0006099|tricarboxylic acid cycle, ! cell fate commitment GO:0045165 141 92 1,000 0,14234751 0,18270049 ! positive regulation of immune response GO:0050778 121 92 1,000 0,14234751 0,18259859 ! sulfur metabolic process GO:0006790 118 92 1,000 0,14234751 0,18249681 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,14482396 0,1855683 ! carbohydrate catabolic process GO:0016052 121 93 1,000 0,14482396 0,18546498 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,1472026 0,18840622 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,1472026 0,18830144 ! viral genome replication GO:0019079 29 22 0,000 0,1472026 0,18819677 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,1472026 0,18809221 ! leukocyte adhesion GO:0007159 38 22 0,000 0,1472026 0,18798777 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,1472026 0,18788345 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,1472026 0,18777925 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,1472026 0,18767516 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,1472026 0,18757118 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,1472026 0,18746732 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,1472026 0,18736358 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,1472026 0,18725995 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,1472026 0,18715643 ! lysosome organization GO:0007040 37 22 0,000 0,1472026 0,18705303 ! ureteric bud development GO:0001657 32 22 0,000 0,1472026 0,18694974 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,1472026 0,18684657 ! regulation of behavior GO:0050795 38 22 0,000 0,1472026 0,18674351 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,1472026 0,18664056 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,1472026 0,18653773 ! membrane depolarization GO:0051899 35 22 0,000 0,1472026 0,18643501 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,1472026 0,18633241 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,1472026 0,18622991 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,1472026 0,18612753 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,1472026 0,18602526 ! blastocyst development GO:0001824 37 22 0,000 0,1472026 0,18592311 ! neural tube closure GO:0001843 33 22 0,000 0,1472026 0,18582107 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,1472026 0,18571913 ! protein tetramerization GO:0051262 39 22 0,000 0,1472026 0,18561731 ! response to oxidative stress GO:0006979 141 94 1,000 0,14730947 0,18565029 ! carboxylic acid transport GO:0046942 147 95 1,000 0,14980379 0,18869043 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 1,000 0,15230668 0,19173801 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,15230668 0,19163313 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,15230668 0,19152835 ! neuron fate commitment GO:0048663 32 23 0,000 0,15335681 0,19274353 ! embryonic pattern specification GO:0009880 31 23 0,000 0,15335681 0,19263826 ! myelination GO:0042552 35 23 0,000 0,15335681 0,19253311 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,15335681 0,19242807 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,15335681 0,19232315 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,15335681 0,19221834 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,15335681 0,19211365 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,15335681 0,19200907 ! vesicle targeting GO:0006903 32 23 0,000 0,15335681 0,1919046 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,15335681 0,19180025 ! osteoblast differentiation GO:0001649 40 23 0,000 0,15335681 0,19169601 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,15335681 0,19159188 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,15335681 0,19148787 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,15335681 0,19138397 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,15335681 0,19128018 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,15335681 0,19117651 ! glycolipid metabolic process GO:0006664 36 23 0,000 0,15335681 0,19107295 ! cell fate determination GO:0001709 45 23 0,000 0,15335681 0,1909695 ! pentose metabolic process GO:0019321 31 23 0,000 0,15335681 0,19086616 ! spermatid development GO:0007286 33 23 0,000 0,15335681 0,19076293 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,15335681 0,19065982 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,15335681 0,19055681 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,15335681 0,19045392 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,15335681 0,19035114 ! telomere organization GO:0032200 32 23 0,000 0,15335681 0,19024847 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,15335681 0,19014591 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,15335681 0,19004346 ! liver development GO:0001889 40 23 0,000 0,15335681 0,18994112 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,15946695 0,19740258 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,15946695 0,19729639 ! initiation of viral infection GO:0019059 42 24 0,000 0,15946695 0,19719032 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,15946695 0,19708436 ! superoxide metabolic process GO:0006801 32 24 0,000 0,15946695 0,19697852 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,15946695 0,19687278 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,15946695 0,19676717 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,15946695 0,19666166 ! sperm motility GO:0030317 27 24 0,000 0,15946695 0,19655627 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,15946695 0,19645099 ! vacuole organization GO:0007033 39 24 0,000 0,15946695 0,19634582 ! receptor metabolic process GO:0043112 37 24 0,000 0,15946695 0,19624077 ! neural crest cell development GO:0014032 39 24 0,000 0,15946695 0,19613583 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,15946695 0,196031 ! primary neural tube formation GO:0014020 35 24 0,000 0,15946695 0,19592628 ! negative regulation of cell development GO:0010721 56 24 0,000 0,15946695 0,19582167 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 0,000 0,15946695 0,19571718 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,15946695 0,1956128 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,15946695 0,19550853 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,15946695 0,19540437 ! glutathione metabolic process GO:0006749 29 24 0,000 0,15946695 0,19530032 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,15946695 0,19519638 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,15946695 0,19509255 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,15946695 0,19498883 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,16239882 0,19846827 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,16239882 0,19836287 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,16553335 0,20208424 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,16553335 0,20197703 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,16553335 0,20186994 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,16553335 0,20176296 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,16553335 0,2016561 ! peptide transport GO:0015833 43 25 0,000 0,16553335 0,20154934 ! male gonad development GO:0008584 33 25 0,000 0,16553335 0,2014427 ! iron ion homeostasis GO:0055072 39 25 0,000 0,16553335 0,20133618 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,16553335 0,20122976 ! phospholipid transport GO:0015914 35 25 0,000 0,16553335 0,20112346 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,16553335 0,20101727 ! detection of light stimulus GO:0009583 30 25 0,000 0,16553335 0,20091119 ! leukocyte proliferation GO:0070661 39 25 0,000 0,16553335 0,20080523 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,16553335 0,20069937 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,17155631 0,20789226 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,17155631 0,20778279 ! translational initiation GO:0006413 43 26 0,000 0,17155631 0,20767343 ! regulation of pH GO:0006885 36 26 0,000 0,17155631 0,20756419 ! circadian rhythm GO:0007623 42 26 0,000 0,17155631 0,20745506 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,17155631 0,20734604 ! post-embryonic development GO:0009791 42 26 0,000 0,17155631 0,20723714 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,17155631 0,20712835 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,17155631 0,20701968 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,17155631 0,20691113 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,17155631 0,20680268 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,17155631 0,20669435 ! regulation of coagulation GO:0050818 39 26 0,000 0,17155631 0,20658613 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,17753614 0,2136751 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,17753614 0,21356335 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,17753614 0,21345171 ! membrane docking GO:0022406 39 27 0,000 0,17753614 0,21334019 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,17753614 0,21322879 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,17753614 0,2131175 ! acute-phase response GO:0006953 42 27 0,000 0,17753614 0,21300632 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,17753614 0,21289527 ! myofibril assembly GO:0030239 36 27 0,000 0,17753614 0,21278433 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,17753614 0,2126735 ! response to ionizing radiation GO:0010212 47 27 0,000 0,17753614 0,21256279 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,17753614 0,2124522 ! natural killer cell activation GO:0030101 35 27 0,000 0,17753614 0,21234172 ! lipid oxidation GO:0034440 38 27 0,000 0,17753614 0,21223135 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,17753614 0,2121211 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,17753614 0,21201097 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,17753614 0,21190095 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,17753614 0,21179104 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,17753614 0,21168125 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,17753614 0,21157157 ! gene silencing GO:0016458 41 27 0,000 0,17753614 0,211462 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,18347315 0,21842041 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,18347315 0,21830742 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,18347315 0,21819454 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,18347315 0,21808178 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,18347315 0,21796913 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,18347315 0,2178566 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,18347315 0,21774419 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,18347315 0,21763189 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,18347315 0,21751971 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,18347315 0,21740764 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,18347315 0,21729569 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,18347315 0,21718386 ! mesoderm formation GO:0001707 46 28 0,000 0,18347315 0,21707214 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,18347315 0,21696053 ! ensheathment of neurons GO:0007272 43 28 0,000 0,18347315 0,21684904 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,18347315 0,21673767 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,18347315 0,21662641 ! neural tube formation GO:0001841 41 28 0,000 0,18347315 0,21651526 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,18347315 0,21640422 ! placenta development GO:0001890 37 28 0,000 0,18347315 0,21629331 ! regulation of B cell activation GO:0050864 42 28 0,000 0,18347315 0,2161825 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,18936763 0,2230136 ! regulation of innate immune response GO:0045088 38 29 0,000 0,18936763 0,22289947 ! ovulation cycle process GO:0022602 41 29 0,000 0,18936763 0,22278545 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,18936763 0,22267155 ! protein targeting to membrane GO:0006612 53 29 0,000 0,18936763 0,22255777 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,18936763 0,22244411 ! mismatch repair GO:0006298 34 29 0,000 0,18936763 0,22233056 ! muscle cell development GO:0055001 38 29 0,000 0,18936763 0,22221712 ! formation of primary germ layer GO:0001704 48 29 0,000 0,18936763 0,2221038 ! telencephalon development GO:0021537 52 29 0,000 0,18936763 0,2219906 ! eye morphogenesis GO:0048592 51 29 0,000 0,18936763 0,22187751 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,18936763 0,22176454 ! tissue homeostasis GO:0001894 42 29 0,000 0,18936763 0,22165168 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,19521991 0,22838544 ! collagen metabolic process GO:0032963 40 30 0,000 0,19521991 0,22826933 ! cholesterol transport GO:0030301 46 30 0,000 0,19521991 0,22815334 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,19521991 0,22803747 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,19521991 0,22792172 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,19521991 0,22780608 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,19521991 0,22769056 ! ceramide metabolic process GO:0006672 43 30 0,000 0,19521991 0,22757516 ! ovulation cycle GO:0042698 43 30 0,000 0,19521991 0,22745987 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,19521991 0,2273447 ! adult locomotory behavior GO:0008344 47 30 0,000 0,19521991 0,22722965 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,19521991 0,22711471 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,19521991 0,22699989 ! response to heat GO:0009408 41 30 0,000 0,19521991 0,22688519 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,19521991 0,2267706 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,19521991 0,22665612 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,20103026 0,23328436 ! negative regulation of secretion GO:0051048 49 31 0,000 0,20103026 0,23316671 ! glial cell differentiation GO:0010001 55 31 0,000 0,20103026 0,23304919 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,20103026 0,23293179 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,20103026 0,2328145 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,20103026 0,23269733 ! segmentation GO:0035282 41 31 0,000 0,20103026 0,23258028 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,20103026 0,23246335 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,20103026 0,23234653 ! metanephros development GO:0001656 58 31 0,000 0,20103026 0,23222983 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,20103026 0,23211325 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,20103026 0,23199679 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,20103026 0,23188044 ! cell fate specification GO:0001708 37 31 0,000 0,20103026 0,23176421 ! RNA modification GO:0009451 40 31 0,000 0,20103026 0,23164809 ! regulation of muscle development GO:0048634 48 32 0,000 0,20679899 0,23817611 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,20679899 0,2380569 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,20679899 0,23793781 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,20679899 0,23781884 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,20679899 0,23769999 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,20679899 0,23758126 ! peripheral nervous system development GO:0007422 53 32 0,000 0,20679899 0,23746265 ! regulation of protein stability GO:0031647 48 32 0,000 0,20679899 0,23734415 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,20679899 0,23722578 ! cytokine production GO:0001816 44 32 0,000 0,20679899 0,23710752 ! vesicle localization GO:0051648 47 32 0,000 0,20679899 0,23698938 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,2125264 0,24343164 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,2125264 0,24331047 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,2125264 0,24318942 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,2125264 0,24306849 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,2125264 0,24294768 ! ear morphogenesis GO:0042471 42 33 0,000 0,2125264 0,24282699 ! actomyosin structure organization GO:0031032 43 33 0,000 0,2125264 0,24270642 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,2125264 0,24258597 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,2125264 0,24246564 ! nucleus organization GO:0006997 49 33 0,000 0,2125264 0,24234543 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,2125264 0,24222534 ! female gonad development GO:0008585 49 33 0,000 0,2125264 0,24210536 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,2125264 0,24198551 ! lipid homeostasis GO:0055088 55 33 0,000 0,2125264 0,24186577 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,2125264 0,24174616 ! regulation of proteolysis GO:0030162 50 33 0,000 0,2125264 0,24162666 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,2125264 0,24150728 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,21821279 0,24784662 ! mRNA catabolic process GO:0006402 48 34 0,000 0,21821279 0,24772429 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,21821279 0,24760208 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,21821279 0,24747998 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,21821279 0,24735801 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,21821279 0,24723616 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,21821279 0,24711443 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,21821279 0,24699282 ! neuron migration GO:0001764 46 34 0,000 0,21821279 0,24687133 ! female gamete generation GO:0007292 43 34 0,000 0,21821279 0,24674996 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,21821279 0,2466287 ! aerobic respiration GO:0009060 47 34 0,000 0,21821279 0,24650757 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,22385843 0,25276111 ! Notch signaling pathway GO:0007219 56 35 0,000 0,22385843 0,25263709 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,22385843 0,25251319 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,22385843 0,25238941 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,22385843 0,25226575 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,22385843 0,25214221 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,22385843 0,25201879 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,22385843 0,25189549 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 48 35 0,000 0,22385843 0,25177232 ! pigment metabolic process GO:0042440 61 35 0,000 0,22385843 0,25164926 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,22385843 0,25152633 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,22946362 0,25769841 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 0,000 0,22946362 0,25757264 ! organic ether metabolic process GO:0018904 46 36 0,000 0,22946362 0,25744699 ! tissue remodeling GO:0048771 62 36 0,000 0,22946362 0,25732147 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,22946362 0,25719607 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,22946362 0,25707079 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,22946362 0,25694564 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,22946362 0,2568206 ! glucan metabolic process GO:0044042 49 36 0,000 0,22946362 0,25669569 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,23502866 0,26279335 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,23502866 0,26266565 ! learning GO:0007612 67 37 0,000 0,23502866 0,26253808 ! ion transmembrane transport GO:0034220 56 37 0,000 0,23502866 0,26241064 ! regulation of protein secretion GO:0050708 51 37 0,000 0,23502866 0,26228332 ! amino acid activation GO:0043038 52 37 0,000 0,23502866 0,26215612 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,23502866 0,26202904 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,24055382 0,268059 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,24055382 0,26792919 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,24055382 0,26779951 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,24603938 0,27377387 ! male sex differentiation GO:0046661 53 39 0,000 0,24603938 0,27364148 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,24603938 0,27350922 ! chromatin remodeling GO:0006338 68 39 0,000 0,24603938 0,27337709 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,24603938 0,27324509 ! JNK cascade GO:0007254 54 39 0,000 0,24603938 0,27311322 ! developmental growth GO:0048589 62 39 0,000 0,24603938 0,27298147 ! synapse organization GO:0050808 55 39 0,000 0,24603938 0,27284985 ! response to calcium ion GO:0051592 58 40 0,000 0,25148564 0,27875517 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,25148564 0,27862089 ! regulation of tube size GO:0035150 60 40 0,000 0,25148564 0,27848675 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,25148564 0,27835273 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,25148564 0,27821884 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,25148564 0,27808508 ! peptide metabolic process GO:0006518 56 40 0,000 0,25148564 0,27795145 ! inner ear development GO:0048839 57 40 0,000 0,25148564 0,27781795 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,25148564 0,27768458 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,25148564 0,27755133 ! double-strand break repair GO:0006302 67 40 0,000 0,25148564 0,27741821 ! B cell differentiation GO:0030183 62 40 0,000 0,25148564 0,27728522 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,25148564 0,27715236 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,25148564 0,27701962 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,25689286 0,2828404 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,25689286 0,28270507 ! glucose transport GO:0015758 52 41 0,000 0,25689286 0,28256986 ! striated muscle contraction GO:0006941 62 41 0,000 0,25689286 0,28243479 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,25689286 0,28229985 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,25689286 0,28216504 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,25689286 0,28203035 ! mitochondrial transport GO:0006839 60 42 0,000 0,26226133 0,28778677 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,26226133 0,28764953 ! cellular component disassembly GO:0022411 64 42 0,000 0,26226133 0,28751243 ! hexose transport GO:0008645 54 42 0,000 0,26226133 0,28737545 GO:0015749|monosaccharide transport, ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,26226133 0,2872386 ! excretion GO:0007588 63 42 0,000 0,26226133 0,28710189 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,26226133 0,2869653 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,26226133 0,28682885 ! regulation of cell shape GO:0008360 78 42 0,000 0,26226133 0,28669252 ! positive regulation of binding GO:0051099 59 43 0,000 0,26759133 0,29238007 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,26759133 0,29224124 ! neuromuscular process GO:0050905 79 43 0,000 0,26759133 0,29210254 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,26759133 0,29196397 ! tRNA processing GO:0008033 49 43 0,000 0,26759133 0,29182553 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,26759133 0,29168723 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,26759133 0,29154905 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,27288312 0,29717385 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,27288312 0,29703321 ! glycolysis GO:0006096 53 44 0,000 0,27288312 0,2968927 ! regulation of action potential GO:0001508 71 44 0,000 0,27288312 0,29675232 ! regulation of ion transport GO:0043269 57 44 0,000 0,27288312 0,29661208 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,27288312 0,29647197 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,27288312 0,296332 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,27288312 0,29619215 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,27288312 0,29605244 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,27288312 0,29591285 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,27288312 0,29577341 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,27288312 0,29563409 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,27288312 0,2954949 ! RNA catabolic process GO:0006401 64 45 0,000 0,27813697 0,30104237 ! positive regulation of defense response GO:0031349 59 45 0,000 0,27813697 0,30090077 ! regulation of translational initiation GO:0006446 64 45 0,000 0,27813697 0,3007593 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,27813697 0,30061797 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,27813697 0,30047676 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,27813697 0,3003357 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,28335316 0,30582462 ! cell redox homeostasis GO:0045454 63 46 0,000 0,28335316 0,30568118 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,28335316 0,30553787 ! histone modification GO:0016570 68 46 0,000 0,28335316 0,30539469 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,28335316 0,30525165 ! response to UV GO:0009411 75 46 0,000 0,28335316 0,30510874 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,28853196 0,31053978 ! viral infectious cycle GO:0019058 71 47 0,000 0,28853196 0,31039453 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,28853196 0,31024942 ! endocrine system development GO:0035270 83 47 0,000 0,28853196 0,31010444 ! covalent chromatin modification GO:0016569 75 47 0,000 0,28853196 0,3099596 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,28853196 0,3098149 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,28853196 0,30967033 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,28853196 0,30952589 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,28853196 0,30938159 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! chloride transport GO:0006821 67 48 0,000 0,29367363 0,31474806 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,29367363 0,31460146 ! response to temperature stimulus GO:0009266 62 48 0,000 0,29367363 0,314455 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,29367363 0,31430867 ! gastrulation GO:0007369 73 48 0,000 0,29367363 0,31416248 ! regulation of DNA replication GO:0006275 75 48 0,000 0,29367363 0,31401643 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,29367363 0,31387051 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,29367363 0,31372473 ! regulation of endocytosis GO:0030100 63 48 0,000 0,29367363 0,31357908 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,29367363 0,31343357 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,29877843 0,31873395 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,29877843 0,31858618 ! sensory perception of smell GO:0007608 61 49 0,000 0,29877843 0,31843855 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,29877843 0,31829105 ! RNA elongation GO:0006354 62 49 0,000 0,29877843 0,3181437 ! germ cell development GO:0007281 68 49 0,000 0,29877843 0,31799648 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,29877843 0,31784939 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,29877843 0,31770244 ! cartilage development GO:0051216 70 49 0,000 0,29877843 0,31755563 ! ear development GO:0043583 72 50 0,000 0,30384663 0,32279319 ! membrane fusion GO:0006944 80 50 0,000 0,30384663 0,32264416 ! lipid modification GO:0030258 73 50 0,000 0,30384663 0,32249527 ! proton transport GO:0015992 75 50 0,000 0,30384663 0,32234652 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,30887849 0,32753366 ! hydrogen transport GO:0006818 77 51 0,000 0,30887849 0,32738273 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,30887849 0,32723193 ! transition metal ion transport GO:0000041 74 52 0,000 0,31387426 0,33237145 ! aging GO:0007568 79 52 0,000 0,31387426 0,3322185 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,31387426 0,33206568 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,31387426 0,33191301 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,3188342 0,33700306 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,3188342 0,33684826 ! kidney development GO:0001822 90 53 0,000 0,3188342 0,3366936 ! single fertilization GO:0007338 59 53 0,000 0,3188342 0,33653909 ! cell projection assembly GO:0030031 76 53 0,000 0,3188342 0,33638471 ! glucose catabolic process GO:0006007 66 54 0,000 0,32375858 0,34142353 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,32375858 0,34126706 ! DNA catabolic process GO:0006308 67 54 0,000 0,32375858 0,34111073 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,32375858 0,34095454 ! exocytosis GO:0006887 74 55 0,000 0,32864763 0,34594487 ! mesoderm development GO:0007498 76 55 0,000 0,32864763 0,34578662 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,32864763 0,34562851 ! carbohydrate transport GO:0008643 74 57 0,000 0,33832078 0,35563885 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,33832078 0,35547638 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,33832078 0,35531406 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,33832078 0,35515189 ! camera-type eye development GO:0043010 88 57 0,000 0,33832078 0,35498987 ! secondary metabolic process GO:0019748 84 57 0,000 0,33832078 0,354828 ! gonad development GO:0008406 79 57 0,000 0,33832078 0,35466627 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,34310538 0,35951816 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,34310538 0,35935445 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,34785565 0,36416385 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,35257184 0,36893322 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,35257184 0,36876545 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,35257184 0,36859783 ! fertilization GO:0009566 68 60 0,000 0,35257184 0,36843036 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,35257184 0,36826305 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,35725419 0,3729844 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,35725419 0,37281517 ! amine catabolic process GO:0009310 90 62 0,000 0,36190295 0,37749514 ! neurotransmitter transport GO:0006836 81 62 0,000 0,36190295 0,37732401 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,36190295 0,37715305 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,36651834 0,38178994 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,36651834 0,38161711 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,37110062 0,38621332 ! hexose catabolic process GO:0019320 82 64 0,000 0,37110062 0,38603864 ! adaptive immune response GO:0002250 94 64 0,000 0,37110062 0,38586412 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! B cell activation GO:0042113 104 65 0,000 0,37565001 0,390418 ! activation of immune response GO:0002253 83 65 0,000 0,37565001 0,39024166 ! antigen processing and presentation GO:0019882 96 66 0,000 0,38016676 0,39475555 ! axon guidance GO:0007411 99 66 0,000 0,38016676 0,39457741 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,38016676 0,39439943 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,38465108 0,39887172 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,38465108 0,39869197 ! acute inflammatory response GO:0002526 92 68 0,000 0,38910322 0,40312495 ! learning or memory GO:0007611 123 68 0,000 0,38910322 0,40294345 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,38910322 0,40276211 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,38910322 0,40258093 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,38910322 0,40239991 ! rhythmic process GO:0048511 105 68 0,000 0,38910322 0,40221906 ! inorganic anion transport GO:0015698 93 68 0,000 0,38910322 0,40203836 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,3935234 0,40642291 ! response to metal ion GO:0010038 103 70 0,000 0,39791184 0,41077075 ! humoral immune response GO:0006959 86 70 0,000 0,39791184 0,41058647 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,39791184 0,41040235 ! regulation of catabolic process GO:0009894 106 70 0,000 0,39791184 0,4102184 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,40226879 0,41452429 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,40226879 0,41433865 ! negative regulation of transport GO:0051051 116 73 0,000 0,41088906 0,42302813 ! mitochondrion organization GO:0007005 104 73 0,000 0,41088906 0,42283885 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,41088906 0,42264975 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,41088906 0,42246081 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,41515283 0,42665394 ! digestion GO:0007586 97 74 0,000 0,41515283 0,42646338 ! blood coagulation GO:0007596 116 75 0,000 0,41938598 0,43061954 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,41938598 0,43042738 ! response to nutrient GO:0007584 104 75 0,000 0,41938598 0,4302354 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,41938598 0,43004358 ! tRNA metabolic process GO:0006399 95 76 0,000 0,42358874 0,43415958 ! response to unfolded protein GO:0006986 99 76 0,000 0,42358874 0,43396619 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,42776131 0,43804587 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,42776131 0,43785092 ! regulation of DNA binding GO:0051101 119 77 0,000 0,42776131 0,43765615 ! sex differentiation GO:0007548 105 77 0,000 0,42776131 0,43746155 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,43190392 0,44150178 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,43190392 0,44130565 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,43601677 0,4453102 ! cellular respiration GO:0045333 107 79 0,000 0,43601677 0,44511255 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,43601677 0,44491507 ! T cell activation GO:0042110 134 79 0,000 0,43601677 0,44471777 ! regulation of lyase activity GO:0051339 133 79 0,000 0,43601677 0,44452065 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,43601677 0,44432369 ! chromatin assembly GO:0031497 102 80 0,000 0,44010009 0,44828618 GO:0006334|nucleosome assembly, ! forebrain development GO:0030900 131 80 0,000 0,44010009 0,44808774 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,44415407 0,4520152 ! hemostasis GO:0007599 125 81 0,000 0,44415407 0,45181528 ! response to protein stimulus GO:0051789 111 81 0,000 0,44415407 0,45161554 ! vitamin metabolic process GO:0006766 103 81 0,000 0,44415407 0,45141598 ! ossification GO:0001503 134 82 0,000 0,44817893 0,45530545 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,45217487 0,45916212 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,45614211 0,46298625 ! sterol metabolic process GO:0016125 120 84 0,000 0,45614211 0,46278203 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,46008084 0,46657228 ! transcription initiation GO:0006352 118 85 0,000 0,46008084 0,46636666 ! regulation of membrane potential GO:0042391 128 85 0,000 0,46008084 0,46616121 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,46008084 0,46595594 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,46399128 0,46970948 ! nucleosome organization GO:0034728 114 87 0,000 0,46787361 0,47343128 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,46787361 0,47322309 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,46787361 0,47301508 ! female pregnancy GO:0007565 130 87 0,000 0,46787361 0,47280725 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,47172805 0,47649298 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,47172805 0,47628381 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,47172805 0,47607482 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,47172805 0,47586601 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,47555479 0,47951601 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,47555479 0,47930588 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,47555479 0,47909593 ! ATP metabolic process GO:0046034 137 91 0,000 0,48312595 0,48651037 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,48687077 0,49006686 ! DNA recombination GO:0006310 146 92 0,000 0,48687077 0,48985248 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,49058867 0,49337732 ! electron transport chain GO:0022900 123 94 0,000 0,49427984 0,49687222 ! regulation of binding GO:0051098 151 95 0,000 0,49794448 0,5003374 ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,50158277 0,50377309 ! protein maturation GO:0051604 129 96 0,000 0,50158277 0,5035532 ! response to light stimulus GO:0009416 153 96 0,000 0,50158277 0,5033335 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,50519491 0,50673715 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,50519491 0,50651626 ! calcium ion transport GO:0006816 167 99 0,000 0,51234145 0,51345766 ! regulation of translation GO:0006417 151 100 0,000 0,51587622 0,51677496 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,51587622 0,51654998 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,51587622 0,5163252 ! divalent metal ion transport GO:0070838 171 100 0,000 0,51587622 0,51610061 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,51587622 0,51587622