pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6578-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! chromosome segregation GO:0007059 38 38 5,000 3,181E-07 5,863E-04 ! mitotic sister chromatid segregation GO:0000070 21 21 4,000 3,763E-07 3,468E-04 ! sister chromatid segregation GO:0000819 22 22 4,000 4,842E-07 2,975E-04 ! spindle organization GO:0007051 22 22 4,000 4,842E-07 2,231E-04 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 3,000 1,374E-06 5,064E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 2,000 4,03E-06 1,238E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 2,000 8,017E-06 2,111E-03 ! regulation of mitotic cell cycle GO:0007346 72 69 5,000 1,156E-05 2,662E-03 ! SMAD protein nuclear translocation GO:0007184 7 7 2,000 1,396E-05 2,858E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 4,000 2,445E-05 4,507E-03 ! regulation of cell cycle process GO:0010564 50 48 4,000 2,714E-05 4,548E-03 ! negative regulation of cell cycle process GO:0010948 9 9 2,000 3,314E-05 5,089E-03 ! positive regulation of protein import into nucleus GO:0042307 9 9 2,000 3,314E-05 4,698E-03 ! epidermis morphogenesis GO:0048730 10 10 2,000 4,708E-05 6,198E-03 ! microtubule cytoskeleton organization GO:0000226 55 55 4,000 5,299E-05 6,51E-03 ! positive regulation of cell cycle GO:0045787 29 29 3,000 5,994E-05 6,905E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 6,439E-05 6,981E-03 GO:0032388|positive regulation of intracellular transport, ! mitotic spindle organization GO:0007052 11 11 2,000 6,439E-05 6,593E-03 ! mitotic chromosome condensation GO:0007076 12 12 2,000 8,54E-05 8,284E-03 ! positive regulation of cellular component organization GO:0051130 65 65 4,000 1,188E-04 0,01095117 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 2,000 1,398E-04 0,01226899 ! collagen fibril organization GO:0030199 14 14 2,000 1,398E-04 0,01171131 ! regulation of mitosis GO:0007088 37 36 3,000 1,43E-04 0,01145582 GO:0051783|regulation of nuclear division, ! protein import into nucleus, translocation GO:0000060 15 15 2,000 1,738E-04 0,01334769 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 1,738E-04 0,01281378 ! chromosome condensation GO:0030261 15 15 2,000 1,738E-04 0,01232094 ! positive regulation of cell motion GO:0051272 39 39 3,000 1,963E-04 0,01340021 ! cell cycle checkpoint GO:0000075 42 41 3,000 2,39E-04 0,01573306 ! negative regulation of ligase activity GO:0051352 43 42 3,000 2,627E-04 0,0166962 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 3,000 2,627E-04 0,01613966 ! negative regulation of organelle organization GO:0010639 45 44 3,000 3,151E-04 0,01873307 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 3,000 3,746E-04 0,02157334 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 3,000 4,417E-04 0,0246679 ! gland development GO:0048732 51 49 3,000 4,783E-04 0,02592577 ! cell cycle arrest GO:0007050 49 49 3,000 4,783E-04 0,02518503 ! regulation of ligase activity GO:0051340 50 49 3,000 4,783E-04 0,02448544 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 4,921E-04 0,02451001 ! prostate gland development GO:0030850 5 5 1,000 5,522E-04 0,02678398 ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 5,522E-04 0,02609721 ! heart looping GO:0001947 5 5 1,000 5,522E-04 0,02544478 ! sister chromatid cohesion GO:0007062 5 5 1,000 5,522E-04 0,02482417 ! cellular glucose homeostasis GO:0001678 5 5 1,000 5,522E-04 0,02423312 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 1,000 5,522E-04 0,02366956 ! DNA methylation GO:0006306 5 5 1,000 5,522E-04 0,02313162 GO:0006305|DNA alkylation, ! positive regulation of epidermis development GO:0045684 5 5 1,000 5,522E-04 0,02261758 ! dopamine biosynthetic process GO:0042416 5 5 1,000 5,522E-04 0,02212589 ! pyrimidine base metabolic process GO:0006206 5 5 1,000 5,522E-04 0,02165513 ! RNA localization GO:0006403 52 52 3,000 6,01E-04 0,02307599 ! response to hypoxia GO:0001666 53 53 3,000 6,465E-04 0,02431462 ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 6,483E-04 0,02389513 ! positive regulation of growth GO:0045927 23 23 2,000 6,483E-04 0,0234266 ! response to oxygen levels GO:0070482 55 54 3,000 6,943E-04 0,02460744 ! glucose homeostasis GO:0042593 24 24 2,000 7,369E-04 0,02562595 GO:0033500|carbohydrate homeostasis, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 8,244E-04 0,02813517 ! virus-host interaction GO:0019048 6 6 1,000 8,244E-04 0,02762362 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 8,244E-04 0,02713034 ! succinate metabolic process GO:0006105 7 6 1,000 8,244E-04 0,02665437 ! artery development GO:0060840 6 6 1,000 8,244E-04 0,02619481 GO:0048844|artery morphogenesis, ! positive regulation of heart contraction GO:0045823 6 6 1,000 8,244E-04 0,02575083 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 1,000 8,244E-04 0,02532165 ! positive regulation of cell growth GO:0030307 6 6 1,000 8,244E-04 0,02490654 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 1,000 8,244E-04 0,02450482 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 8,244E-04 0,02411586 ! salivary gland morphogenesis GO:0007435 6 6 1,000 8,244E-04 0,02373905 ! thymus development GO:0048538 6 6 1,000 8,244E-04 0,02337383 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 8,33E-04 0,02326025 ! heart morphogenesis GO:0003007 25 25 2,000 8,33E-04 0,02291308 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 2,000 9,366E-04 0,0253852 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 1,048E-03 0,02799492 ! proteasomal protein catabolic process GO:0010498 62 61 3,000 1,102E-03 0,02901191 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,149E-03 0,02981311 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 1,149E-03 0,02939904 ! hair follicle morphogenesis GO:0031069 7 7 1,000 1,149E-03 0,02899631 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 1,149E-03 0,02860447 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 1,000 1,149E-03 0,02822308 ! endothelial cell differentiation GO:0045446 7 7 1,000 1,149E-03 0,02785172 ! regulation of defense response to virus GO:0050688 7 7 1,000 1,149E-03 0,02749001 ! dopamine metabolic process GO:0042417 7 7 1,000 1,149E-03 0,02713758 ! negative regulation of cellular component organization GO:0051129 65 63 3,000 1,244E-03 0,02901817 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 1,295E-03 0,02984389 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,295E-03 0,02947545 ! regulation of gene expression, epigenetic GO:0040029 29 29 2,000 1,295E-03 0,02911599 ! positive regulation of protein transport GO:0051222 29 29 2,000 1,295E-03 0,0287652 ! embryonic forelimb morphogenesis GO:0035115 8 8 1,000 1,524E-03 0,03343648 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 1,000 1,524E-03 0,03304311 ! phosphagen metabolic process GO:0006599 8 8 1,000 1,524E-03 0,03265889 GO:0006600|creatine metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 1,524E-03 0,0322835 ! salivary gland development GO:0007431 8 8 1,000 1,524E-03 0,03191664 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 1,524E-03 0,03155803 ! T cell homeostasis GO:0043029 8 8 1,000 1,524E-03 0,03120738 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 1,524E-03 0,03086444 ! catecholamine biosynthetic process GO:0042423 8 8 1,000 1,524E-03 0,03052896 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 1,000 1,524E-03 0,03020069 ! regulation of multi-organism process GO:0043900 8 8 1,000 1,524E-03 0,02987941 ! extracellular matrix organization GO:0030198 31 31 2,000 1,577E-03 0,03058861 ! regulation of intracellular transport GO:0032386 31 31 2,000 1,577E-03 0,03026998 ! negative regulation of cell growth GO:0030308 32 32 2,000 1,731E-03 0,0328816 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 1,731E-03 0,03254607 ! positive regulation of transport GO:0051050 71 70 3,000 1,842E-03 0,03428365 ! negative regulation of cell size GO:0045792 33 33 2,000 1,894E-03 0,03489854 ! activation of protein kinase activity GO:0032147 35 33 2,000 1,894E-03 0,03455301 ! positive regulation of cell size GO:0045793 9 9 1,000 1,95E-03 0,03523227 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 1,000 1,95E-03 0,03489021 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 1,000 1,95E-03 0,03455473 ! nucleobase biosynthetic process GO:0046112 9 9 1,000 1,95E-03 0,03422563 ! regulation of dephosphorylation GO:0035303 9 9 1,000 1,95E-03 0,03390275 ! forelimb morphogenesis GO:0035136 10 10 1,000 2,426E-03 0,04177963 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 2,426E-03 0,04139278 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 2,426E-03 0,04101303 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! exocrine system development GO:0035272 10 10 1,000 2,426E-03 0,04064019 ! protein export from nucleus GO:0006611 10 10 1,000 2,426E-03 0,04027406 ! negative regulation of immune response GO:0050777 10 10 1,000 2,426E-03 0,03991447 ! gland morphogenesis GO:0022612 10 10 1,000 2,426E-03 0,03956124 ! regulation of epidermis development GO:0045682 10 10 1,000 2,426E-03 0,03921422 ! regulation of BMP signaling pathway GO:0030510 10 10 1,000 2,426E-03 0,03887322 ! lymphocyte homeostasis GO:0002260 10 10 1,000 2,426E-03 0,03853811 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 2,426E-03 0,03820872 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,426E-03 0,03788492 ! negative regulation of coagulation GO:0050819 11 10 1,000 2,426E-03 0,03756656 ! positive regulation of cell migration GO:0030335 36 36 2,000 2,439E-03 0,03745616 ! positive regulation of organelle organization GO:0010638 36 36 2,000 2,439E-03 0,0371466 ! meiosis GO:0007126 37 37 2,000 2,64E-03 0,03988043 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 2,000 2,64E-03 0,0395562 ! negative regulation of growth GO:0045926 37 37 2,000 2,64E-03 0,03923719 ! positive regulation of protein kinase cascade GO:0010740 79 78 3,000 2,741E-03 0,04040698 ! meiotic cell cycle GO:0051321 38 38 2,000 2,851E-03 0,04170207 ! nuclear transport GO:0051169 79 79 3,000 2,871E-03 0,04166001 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 3,000 2,871E-03 0,04133455 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 2,95E-03 0,04215096 ! phosphatidylinositol metabolic process GO:0046488 11 11 1,000 2,95E-03 0,04182672 ! skin development GO:0043588 11 11 1,000 2,95E-03 0,04150744 ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 2,95E-03 0,04119299 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! cellular response to starvation GO:0009267 11 11 1,000 2,95E-03 0,04088326 ! interaction with host GO:0051701 11 11 1,000 2,95E-03 0,04057817 ! hindbrain development GO:0030902 11 11 1,000 2,95E-03 0,04027759 ! proximal/distal pattern formation GO:0009954 11 11 1,000 2,95E-03 0,03998143 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 3,523E-03 0,04739774 ! positive regulation of endocytosis GO:0045807 12 12 1,000 3,523E-03 0,04705427 ! barbed-end actin filament capping GO:0051016 12 12 1,000 3,523E-03 0,04671575 GO:0051693|actin filament capping, ! regulation of chromosome organization GO:0033044 12 12 1,000 3,523E-03 0,04638207 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 3,523E-03 0,04605312 ! regulation of response to biotic stimulus GO:0002831 12 12 1,000 3,523E-03 0,0457288 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 1,000 3,523E-03 0,04540902 ! regulation of caspase activity GO:0043281 41 41 2,000 3,546E-03 0,04538045 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 3,798E-03 0,04827735 ! negative regulation of actin filament polymerization GO:0030837 13 13 1,000 4,144E-03 0,05230904 ! phenol metabolic process GO:0018958 13 13 1,000 4,144E-03 0,0519532 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 4,144E-03 0,05160216 ! patterning of blood vessels GO:0001569 13 13 1,000 4,144E-03 0,05125584 ! vasculogenesis GO:0001570 13 13 1,000 4,144E-03 0,05091413 ! actin filament bundle formation GO:0051017 13 13 1,000 4,144E-03 0,05057695 ! nucleobase metabolic process GO:0009112 13 13 1,000 4,144E-03 0,05024421 ! neutrophil chemotaxis GO:0030593 14 13 1,000 4,144E-03 0,04991582 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 4,144E-03 0,04959169 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 1,000 4,144E-03 0,04927174 ! positive regulation of transferase activity GO:0051347 91 88 3,000 4,239E-03 0,05007558 GO:0033674|positive regulation of kinase activity, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 4,336E-03 0,05089578 ! protein import into nucleus GO:0006606 44 44 2,000 4,336E-03 0,05057365 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 4,621E-03 0,05356052 ! nuclear import GO:0051170 45 45 2,000 4,621E-03 0,05322576 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 1,000 4,811E-03 0,05507473 ! hair cycle GO:0042633 14 14 1,000 4,811E-03 0,05473477 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! DNA modification GO:0006304 14 14 1,000 4,811E-03 0,05439897 ! regulation of blood coagulation GO:0030193 15 14 1,000 4,811E-03 0,05406727 ! negative regulation of protein polymerization GO:0032272 14 14 1,000 4,811E-03 0,05373959 ! tube morphogenesis GO:0035239 47 46 2,000 4,917E-03 0,054591 ! regulation of peptidase activity GO:0052547 46 46 2,000 4,917E-03 0,05426411 ! positive regulation of ligase activity GO:0051351 47 46 2,000 4,917E-03 0,05394111 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 4,917E-03 0,05362193 ! tissue morphogenesis GO:0048729 94 93 3,000 5,162E-03 0,05596456 ! regulation of response to stress GO:0080134 97 94 3,000 5,362E-03 0,05778931 ! blood vessel development GO:0001568 95 94 3,000 5,362E-03 0,05745333 ! pattern specification process GO:0007389 96 94 3,000 5,362E-03 0,05712123 ! negative regulation of actin filament depolymerization GO:0030835 15 15 1,000 5,525E-03 0,05851671 ! positive regulation of ossification GO:0045778 15 15 1,000 5,525E-03 0,05818233 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 5,525E-03 0,05785174 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 5,525E-03 0,0575249 ! response to starvation GO:0042594 15 15 1,000 5,525E-03 0,05720172 ! leukocyte homeostasis GO:0001776 15 15 1,000 5,525E-03 0,05688216 ! protein homooligomerization GO:0051260 15 15 1,000 5,525E-03 0,05656615 ! protein localization in nucleus GO:0034504 48 48 2,000 5,543E-03 0,05644457 ! vasculature development GO:0001944 97 96 3,000 5,777E-03 0,05849673 ! RNA transport GO:0050658 50 50 2,000 6,216E-03 0,06259797 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! anterior/posterior pattern formation GO:0009952 51 50 2,000 6,216E-03 0,06225776 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 6,283E-03 0,06259698 ! positive regulation of mitosis GO:0045840 16 16 1,000 6,283E-03 0,06226044 GO:0051785|positive regulation of nuclear division, ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 6,283E-03 0,06192749 ! positive regulation of cell development GO:0010720 16 16 1,000 6,283E-03 0,06159809 ! positive regulation of MAPKKK cascade GO:0043410 17 16 1,000 6,283E-03 0,06127217 ! cellular response to nutrient levels GO:0031669 16 16 1,000 6,283E-03 0,06094969 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 6,283E-03 0,06063058 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 6,283E-03 0,0603148 ! regulation of coagulation GO:0050818 17 16 1,000 6,283E-03 0,06000228 ! regulation of actin filament depolymerization GO:0030834 17 17 1,000 7,087E-03 0,06732651 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 7,087E-03 0,06698125 ! regulation of transmembrane transport GO:0034762 17 17 1,000 7,087E-03 0,06663951 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 7,087E-03 0,06630124 ! pigmentation GO:0043473 17 17 1,000 7,087E-03 0,06596638 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 2,000 7,312E-03 0,06771819 ! regulation of protein transport GO:0051223 53 53 2,000 7,312E-03 0,0673796 GO:0070201|regulation of establishment of protein localization, ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 7,935E-03 0,07275293 ! regulation of microtubule-based process GO:0032886 18 18 1,000 7,935E-03 0,07239277 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 7,935E-03 0,07203616 ! meiosis I GO:0007127 18 18 1,000 7,935E-03 0,07168304 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 7,935E-03 0,07133336 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 7,935E-03 0,07098709 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! extracellular structure organization GO:0043062 56 56 2,000 8,516E-03 0,07582177 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 8,825E-03 0,07819792 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 8,825E-03 0,07782377 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 8,825E-03 0,07745318 ! ribonucleoside metabolic process GO:0009119 19 19 1,000 8,825E-03 0,0770861 ! cellular response to oxidative stress GO:0034599 19 19 1,000 8,825E-03 0,07672249 ! biogenic amine biosynthetic process GO:0042401 20 19 1,000 8,825E-03 0,07636229 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 8,825E-03 0,07600545 ! regulation of protein localization GO:0032880 58 57 2,000 8,942E-03 0,07664993 ! neural tube development GO:0021915 21 20 1,000 9,759E-03 0,08326656 ! chromatin remodeling GO:0006338 20 20 1,000 9,759E-03 0,08288284 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 9,759E-03 0,08250265 ! cellular aromatic compound metabolic process GO:0006725 60 59 2,000 9,83E-03 0,08272696 ! protein localization in organelle GO:0033365 59 59 2,000 9,83E-03 0,08235093 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 0,01073431 0,08951736 ! mammary gland development GO:0030879 23 21 1,000 0,01073431 0,08911412 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 0,01073431 0,08871451 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,01073431 0,08831846 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01073431 0,08792594 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 0,01073431 0,08753688 ! protein import GO:0017038 62 62 2,000 0,01125657 0,09139144 ! RNA export from nucleus GO:0006405 22 22 1,000 0,01175107 0,09498781 ! cellular amide metabolic process GO:0043603 22 22 1,000 0,01175107 0,09457302 ! odontogenesis GO:0042476 22 22 1,000 0,01175107 0,09416183 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01175107 0,09375421 ! cell chemotaxis GO:0060326 23 22 1,000 0,01175107 0,09335009 GO:0030595|leukocyte chemotaxis, ! biopolymer methylation GO:0043414 22 22 1,000 0,01175107 0,09294945 GO:0032259|methylation, ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 0,01175107 0,09255223 ! cytokinesis GO:0000910 23 22 1,000 0,01175107 0,09215839 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 1,000 0,01175107 0,09176789 ! angiogenesis GO:0001525 65 64 2,000 0,01227054 0,09542026 ! regulation of cytoskeleton organization GO:0051493 66 64 2,000 0,01227054 0,09501934 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,01280848 0,09876999 ! negative regulation of protein complex disassembly GO:0043242 23 23 1,000 0,01280848 0,09835845 ! Rho protein signal transduction GO:0007266 24 23 1,000 0,01280848 0,09795032 ! DNA packaging GO:0006323 66 66 2,000 0,0133355 0,10155922 ! gliogenesis GO:0042063 24 24 1,000 0,01390589 0,10546733 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 0,01390589 0,10503508 ! maintenance of protein location GO:0045185 25 24 1,000 0,01390589 0,10460637 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01390589 0,10418114 ! regulation of cell size GO:0008361 68 68 2,000 0,01445184 0,10783295 ! regionalization GO:0003002 70 69 2,000 0,01502938 0,11169007 ! regulation of actin filament polymerization GO:0030833 25 25 1,000 0,01504267 0,11133991 ! regulation of endocytosis GO:0030100 25 25 1,000 0,01504267 0,11089455 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01504267 0,11045274 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01504267 0,11001443 ! wound healing GO:0042060 74 70 2,000 0,01561987 0,11378429 ! growth GO:0040007 70 70 2,000 0,01561987 0,11333632 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 0,01621817 0,11721604 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01621817 0,11675817 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01621817 0,11630385 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01621817 0,11585306 ! translational elongation GO:0006414 71 71 2,000 0,01622336 0,1154427 ! regulation of cell migration GO:0030334 71 71 2,000 0,01622336 0,11499869 ! regulation of cytokine production GO:0001817 72 72 2,000 0,01683988 0,11891147 ! activation of caspase activity GO:0006919 27 27 1,000 0,01743178 0,12262124 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01743178 0,122155 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! cell growth GO:0016049 27 27 1,000 0,01743178 0,12169229 ! positive regulation of multicellular organismal process GO:0051240 76 76 2,000 0,01943667 0,13517653 ! viral reproductive process GO:0022415 29 29 1,000 0,01997082 0,13836927 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,01997082 0,13785103 ! leukocyte migration GO:0050900 30 29 1,000 0,01997082 0,13733666 ! regulation of protein polymerization GO:0032271 29 29 1,000 0,01997082 0,13682611 ! regulation of immune response GO:0050776 78 78 2,000 0,02081377 0,14207326 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,02129504 0,144822 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,02129504 0,14428957 GO:0043280|positive regulation of caspase activity, ! regulation of protein complex disassembly GO:0043244 30 30 1,000 0,02129504 0,14376103 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,02129504 0,14323636 ! regulation of ossification GO:0030278 30 30 1,000 0,02129504 0,1427155 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 1,000 0,02129504 0,14219841 ! establishment of organelle localization GO:0051656 31 30 1,000 0,02129504 0,14168506 ! regulation of locomotion GO:0040012 79 79 2,000 0,02152205 0,14268034 ! negative regulation of cytoskeleton organization GO:0051494 32 31 1,000 0,02265493 0,14965243 ! nucleoside metabolic process GO:0009116 31 31 1,000 0,02265493 0,14911795 ! regulation of heart contraction GO:0008016 31 31 1,000 0,02265493 0,14858728 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,02265493 0,14806038 ! tube development GO:0035295 83 81 2,000 0,02297809 0,14964177 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,02404988 0,15607017 ! cell maturation GO:0048469 32 32 1,000 0,02404988 0,15552255 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,02404988 0,15497877 ! nuclear export GO:0051168 32 32 1,000 0,02404988 0,15443877 ! maintenance of location GO:0051235 33 32 1,000 0,02404988 0,15390253 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,02448681 0,15615635 ! cellular amino acid derivative metabolic process GO:0006575 87 84 2,000 0,02526092 0,16053749 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,02547932 0,16136902 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,02547932 0,16081638 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 0,02547932 0,16026752 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02547932 0,15972239 ! regulation of cellular localization GO:0060341 86 85 2,000 0,02604819 0,16273497 ! nitrogen compound biosynthetic process GO:0044271 86 85 2,000 0,02604819 0,16218519 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 0,02684862 0,1666061 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,02684862 0,16604702 ! regulation of actin filament length GO:0030832 34 34 1,000 0,02694266 0,16607133 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,02694266 0,16551776 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,02694266 0,16496787 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 0,02694266 0,16442162 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,02694266 0,16387897 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,02694266 0,16333989 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 0,02694266 0,16280435 ! viral reproduction GO:0016032 34 34 1,000 0,02694266 0,16227231 ! heart development GO:0007507 90 87 2,000 0,0276622 0,16606331 ! regulation of cellular component size GO:0032535 35 35 1,000 0,02843934 0,17017436 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02843934 0,16962363 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,02843934 0,16907646 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,02843934 0,16853281 ! regulation of immune effector process GO:0002697 35 35 1,000 0,02843934 0,16799264 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,02996878 0,17646155 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,02996878 0,17589957 GO:0045937|positive regulation of phosphate metabolic process, ! coagulation GO:0050817 39 36 1,000 0,02996878 0,17534116 GO:0007596|blood coagulation, ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,03104773 0,18107902 ! lung development GO:0030324 38 37 1,000 0,03153043 0,18331414 ! eye development GO:0001654 37 37 1,000 0,03153043 0,18273768 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,03153043 0,18216484 ! fatty acid metabolic process GO:0006631 93 92 2,000 0,03192684 0,18387862 ! urogenital system development GO:0001655 38 38 1,000 0,03312373 0,19017768 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,03312373 0,18958706 ! epidermis development GO:0008544 94 94 2,000 0,03372417 0,19242614 ! hemostasis GO:0007599 42 39 1,000 0,03474813 0,19765682 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,03474813 0,19704865 ! activation of MAPK activity GO:0000187 39 39 1,000 0,03474813 0,1964442 ! respiratory tube development GO:0030323 40 39 1,000 0,03474813 0,19584346 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,03474813 0,19524637 ! intracellular protein transmembrane transport GO:0065002 39 39 1,000 0,03474813 0,19465292 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,03474813 0,19406306 ! respiratory system development GO:0060541 40 39 1,000 0,03474813 0,19347677 ! developmental maturation GO:0021700 39 39 1,000 0,03474813 0,19289401 ! limb development GO:0060173 39 39 1,000 0,03474813 0,19231475 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 1,000 0,03474813 0,19173895 ! regulation of cell growth GO:0001558 97 96 2,000 0,0355735 0,19570734 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,0364031 0,19967534 ! organelle localization GO:0051640 41 40 1,000 0,0364031 0,19908283 ! rRNA transcription GO:0009303 5 5 0,000 0,03723441 0,20302666 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03723441 0,20242776 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03723441 0,20183238 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03723441 0,2012405 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03723441 0,20065208 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03723441 0,20006709 ! reproductive cellular process GO:0048610 5 5 0,000 0,03723441 0,1994855 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03723441 0,19890728 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03723441 0,1983324 ! metencephalon development GO:0022037 5 5 0,000 0,03723441 0,19776084 ! water transport GO:0006833 5 5 0,000 0,03723441 0,19719256 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03723441 0,19662754 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03723441 0,19606574 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03723441 0,19550715 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03723441 0,19495173 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03723441 0,19439946 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03723441 0,19385031 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03723441 0,19330426 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03723441 0,19276127 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03723441 0,19222132 ! filopodium assembly GO:0046847 7 5 0,000 0,03723441 0,19168439 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03723441 0,19115045 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03723441 0,19061947 ! GTP metabolic process GO:0046039 5 5 0,000 0,03723441 0,19009144 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03723441 0,18956633 ! mRNA stabilization GO:0048255 5 5 0,000 0,03723441 0,18904411 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03723441 0,18852475 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03723441 0,18800825 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03723441 0,18749456 ! social behavior GO:0035176 5 5 0,000 0,03723441 0,18698368 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03723441 0,18647557 ! memory GO:0007613 5 5 0,000 0,03723441 0,18597022 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03723441 0,1854676 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03723441 0,18496768 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03723441 0,18447046 ! response to lipid GO:0033993 5 5 0,000 0,03723441 0,1839759 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03723441 0,18348399 ! hippocampus development GO:0021766 6 5 0,000 0,03723441 0,18299469 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03723441 0,18250801 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03723441 0,1820239 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03723441 0,18154236 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03723441 0,18106335 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03723441 0,18058687 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03723441 0,18011289 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03723441 0,17964139 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03723441 0,17917235 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03723441 0,17870576 ! pH reduction GO:0045851 5 5 0,000 0,03723441 0,17824159 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03723441 0,17777982 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03723441 0,17732044 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03723441 0,17686343 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03723441 0,17640877 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03723441 0,17595644 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03723441 0,17550642 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03723441 0,1750587 ! adrenal gland development GO:0030325 5 5 0,000 0,03723441 0,17461326 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03723441 0,17417008 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03723441 0,17372914 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03723441 0,17329043 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03723441 0,17285393 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03723441 0,17241962 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03723441 0,1719875 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03723441 0,17155753 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03723441 0,1711297 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03723441 0,17070401 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03723441 0,17028042 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03723441 0,16985894 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03723441 0,16943953 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03723441 0,16902219 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03723441 0,16860691 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03723441 0,16819365 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03723441 0,16778242 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03723441 0,1673732 GO:0021952|central nervous system projection neuron axonogenesis, ! response to ATP GO:0033198 5 5 0,000 0,03723441 0,16696596 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03723441 0,16656071 ! regulation of appetite GO:0032098 5 5 0,000 0,03723441 0,16615741 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03723441 0,16575606 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03723441 0,16535665 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,03723441 0,16495916 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03723441 0,16456357 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03723441 0,16416988 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03723441 0,16377807 ! receptor clustering GO:0043113 5 5 0,000 0,03723441 0,16338812 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03723441 0,16300003 ! fear response GO:0042596 5 5 0,000 0,03723441 0,16261377 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03723441 0,16222934 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03723441 0,16184672 ! retinol metabolic process GO:0042572 5 5 0,000 0,03723441 0,16146591 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03723441 0,16108688 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03723441 0,16070963 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03723441 0,16033414 ! parturition GO:0007567 5 5 0,000 0,03723441 0,1599604 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03723441 0,1595884 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03723441 0,15921812 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03723441 0,15884956 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03723441 0,1584827 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03723441 0,15811754 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03723441 0,15775405 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03723441 0,15739223 ! response to UV-B GO:0010224 5 5 0,000 0,03723441 0,15703206 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03723441 0,15667354 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03723441 0,15631665 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03723441 0,15596139 ! interaction with symbiont GO:0051702 5 5 0,000 0,03723441 0,15560773 ! cellular extravasation GO:0045123 5 5 0,000 0,03723441 0,15525568 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03723441 0,15490522 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03723441 0,15455633 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03723441 0,15420901 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03723441 0,15386325 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03723441 0,15351904 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03723441 0,15317636 ! response to amine stimulus GO:0014075 5 5 0,000 0,03723441 0,15283521 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03723441 0,15249558 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03723441 0,15215745 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03723441 0,15182082 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03723441 0,15148567 ! neuron recognition GO:0008038 5 5 0,000 0,03723441 0,15115201 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03723441 0,1508198 ! decidualization GO:0046697 5 5 0,000 0,03723441 0,15048906 ! hair follicle maturation GO:0048820 5 5 0,000 0,03723441 0,15015976 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03723441 0,1498319 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03723441 0,14950547 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03723441 0,14918046 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03723441 0,14885686 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03723441 0,14853465 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03723441 0,14821385 ! postreplication repair GO:0006301 5 5 0,000 0,03723441 0,14789442 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03723441 0,14757637 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03723441 0,14725968 ! histone methylation GO:0016571 5 5 0,000 0,03723441 0,14694435 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03723441 0,14663036 ! T cell lineage commitment GO:0002360 5 5 0,000 0,03723441 0,14631772 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03723441 0,14600641 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03723441 0,14569641 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03723441 0,14538773 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03723441 0,14508036 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03723441 0,14477428 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03723441 0,1444695 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03723441 0,14416599 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03723441 0,14386375 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03723441 0,14356278 ! sterol catabolic process GO:0016127 5 5 0,000 0,03723441 0,14326307 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03723441 0,14296461 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03723441 0,14266738 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03723441 0,14237139 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03723441 0,14207663 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03723441 0,14178308 ! zymogen activation GO:0031638 5 5 0,000 0,03723441 0,14149074 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03723441 0,14119961 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03723441 0,14090967 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03723441 0,14062092 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,03723441 0,14033335 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,03723441 0,14004696 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03723441 0,13976173 ! nucleosome positioning GO:0016584 5 5 0,000 0,03723441 0,13947766 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03723441 0,13919475 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03723441 0,13891298 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03723441 0,13863234 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03723441 0,13835284 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03723441 0,13807447 ! NADPH regeneration GO:0006740 5 5 0,000 0,03723441 0,13779721 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03723441 0,13752106 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03723441 0,13724602 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03723441 0,13697208 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03723441 0,13669922 ! sarcomere organization GO:0045214 5 5 0,000 0,03723441 0,13642746 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03723441 0,13615677 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03723441 0,13588715 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03723441 0,1356186 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03723441 0,13535111 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03723441 0,13508467 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03723441 0,13481927 ! spleen development GO:0048536 5 5 0,000 0,03723441 0,13455492 ! male genitalia development GO:0030539 5 5 0,000 0,03723441 0,13429161 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03723441 0,13402932 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03723441 0,13376805 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03723441 0,1335078 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03723441 0,13324856 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03723441 0,13299033 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03723441 0,1327331 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03723441 0,13247685 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03723441 0,1322216 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03723441 0,13196733 ! ATP catabolic process GO:0006200 5 5 0,000 0,03723441 0,13171403 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03723441 0,13146171 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03723441 0,13121035 ! blastocyst formation GO:0001825 5 5 0,000 0,03723441 0,13095994 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03723441 0,1307105 ! embryonic gut development GO:0048566 5 5 0,000 0,03723441 0,130462 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03723441 0,13021444 ! activation of innate immune response GO:0002218 5 5 0,000 0,03723441 0,12996782 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,03723441 0,12972214 ! catecholamine transport GO:0051937 5 5 0,000 0,03723441 0,12947738 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03723441 0,12923354 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03723441 0,12899062 ! muscle adaptation GO:0043500 5 5 0,000 0,03723441 0,12874861 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03723441 0,12850751 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03723441 0,12826731 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03723441 0,128028 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03723441 0,12778959 ! defense response to fungus GO:0050832 5 5 0,000 0,03723441 0,12755206 ! lysogeny GO:0030069 5 5 0,000 0,03723441 0,12731542 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03723441 0,12707965 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03723441 0,12684475 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03723441 0,12661072 ! response to nicotine GO:0035094 5 5 0,000 0,03723441 0,12637755 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03723441 0,12614524 ! mitochondrion localization GO:0051646 5 5 0,000 0,03723441 0,12591378 ! nucleus localization GO:0051647 5 5 0,000 0,03723441 0,12568317 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03723441 0,1254534 ! ectoderm development GO:0007398 99 99 2,000 0,03844448 0,12929413 ! response to hormone stimulus GO:0009725 102 100 2,000 0,03942721 0,13235766 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,03942721 0,13211701 ! response to other organism GO:0051707 101 100 2,000 0,03942721 0,13187723 ! protein ubiquitination GO:0016567 43 42 1,000 0,03980258 0,1328916 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,03980258 0,13265129 ! reproductive structure development GO:0048608 43 43 1,000 0,04154605 0,13821186 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,04154605 0,13796283 ! mRNA transport GO:0051028 44 44 1,000 0,04331797 0,14358817 ! axon extension GO:0048675 7 6 0,000 0,04451642 0,14729579 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04451642 0,14703182 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,04451642 0,14676879 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,04451642 0,1465067 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04451642 0,14624555 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04451642 0,14598533 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04451642 0,14572603 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04451642 0,14546765 ! regulation of S phase GO:0033261 6 6 0,000 0,04451642 0,14521018 ! myotube differentiation GO:0014902 6 6 0,000 0,04451642 0,14495363 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04451642 0,14469798 ! bone remodeling GO:0046849 6 6 0,000 0,04451642 0,14444323 ! N-glycan processing GO:0006491 6 6 0,000 0,04451642 0,14418937 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04451642 0,14393641 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04451642 0,14368433 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04451642 0,14343313 ! RNA methylation GO:0001510 6 6 0,000 0,04451642 0,14318281 ! cartilage condensation GO:0001502 7 6 0,000 0,04451642 0,14293337 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04451642 0,14268479 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04451642 0,14243707 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04451642 0,14219021 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04451642 0,14194421 ! androgen metabolic process GO:0008209 6 6 0,000 0,04451642 0,14169906 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04451642 0,14145475 ! limbic system development GO:0021761 7 6 0,000 0,04451642 0,14121128 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04451642 0,14096865 ! pathogenesis GO:0009405 6 6 0,000 0,04451642 0,14072685 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04451642 0,14048588 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04451642 0,14024573 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04451642 0,1400064 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04451642 0,13976789 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04451642 0,13953019 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04451642 0,1392933 ! arginine metabolic process GO:0006525 6 6 0,000 0,04451642 0,13905721 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04451642 0,13882192 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04451642 0,13858742 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04451642 0,13835371 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04451642 0,1381208 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04451642 0,13788866 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04451642 0,1376573 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04451642 0,13742672 ! ER overload response GO:0006983 6 6 0,000 0,04451642 0,13719691 ! V(D)J recombination GO:0033151 6 6 0,000 0,04451642 0,13696787 ! focal adhesion formation GO:0048041 7 6 0,000 0,04451642 0,13673959 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04451642 0,13651207 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,04451642 0,1362853 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04451642 0,13605929 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04451642 0,13583403 ! regulation of heart rate GO:0002027 6 6 0,000 0,04451642 0,13560951 ! lipid digestion GO:0044241 6 6 0,000 0,04451642 0,13538573 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04451642 0,13516269 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04451642 0,13494038 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04451642 0,13471881 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04451642 0,13449796 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04451642 0,13427783 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04451642 0,13405842 ! ruffle organization GO:0031529 6 6 0,000 0,04451642 0,13383973 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,04451642 0,13362175 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04451642 0,13340448 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04451642 0,13318791 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04451642 0,13297205 ! L-amino acid transport GO:0015807 6 6 0,000 0,04451642 0,13275688 ! bone mineralization GO:0030282 6 6 0,000 0,04451642 0,13254241 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04451642 0,13232863 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04451642 0,13211554 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04451642 0,13190314 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,04451642 0,13169142 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04451642 0,13148037 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04451642 0,13127 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,04451642 0,13106031 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04451642 0,13085128 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04451642 0,13064292 ! regulation of organ growth GO:0046620 6 6 0,000 0,04451642 0,13043522 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04451642 0,13022818 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04451642 0,1300218 ! response to dsRNA GO:0043331 6 6 0,000 0,04451642 0,12981606 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04451642 0,12961098 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04451642 0,12940655 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,04451642 0,12920276 ! genitalia development GO:0048806 6 6 0,000 0,04451642 0,12899961 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04451642 0,1287971 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04451642 0,12859522 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04451642 0,12839398 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04451642 0,12819336 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04451642 0,12799337 ! erythrocyte development GO:0048821 6 6 0,000 0,04451642 0,12779401 ! renal water homeostasis GO:0003091 6 6 0,000 0,04451642 0,12759526 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04451642 0,12739713 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04451642 0,12719962 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04451642 0,12700271 ! ribosome assembly GO:0042255 6 6 0,000 0,04451642 0,12680642 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04451642 0,12661073 ! diencephalon development GO:0021536 6 6 0,000 0,04451642 0,12641564 ! fucose catabolic process GO:0019317 6 6 0,000 0,04451642 0,12622116 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04451642 0,12602727 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04451642 0,12583398 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04451642 0,12564128 ! regulation of cell division GO:0051302 6 6 0,000 0,04451642 0,12544916 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04451642 0,12525764 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04451642 0,1250667 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04451642 0,12487634 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04451642 0,12468655 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04451642 0,12449735 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04451642 0,12430872 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04451642 0,12412065 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04451642 0,12393316 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04451642 0,12374623 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04451642 0,12355987 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04451642 0,12337406 ! lymph node development GO:0048535 6 6 0,000 0,04451642 0,12318882 ! organic cation transport GO:0015695 6 6 0,000 0,04451642 0,12300413 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04451642 0,12281999 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04451642 0,1226364 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04451642 0,12245336 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04451642 0,12227087 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04451642 0,12208892 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04451642 0,12190751 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04451642 0,12172664 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04451642 0,1215463 ! alditol metabolic process GO:0019400 6 6 0,000 0,04451642 0,1213665 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04451642 0,12118723 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04451642 0,12100849 ! maternal placenta development GO:0001893 6 6 0,000 0,04451642 0,12083027 ! regulation of embryonic development GO:0045995 6 6 0,000 0,04451642 0,12065258 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04451642 0,12047541 ! localization within membrane GO:0051668 6 6 0,000 0,04451642 0,12029876 ! amine biosynthetic process GO:0009309 46 45 1,000 0,04511784 0,12174551 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,04511784 0,12156752 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,04511784 0,12139005 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,04511784 0,12121309 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,04694515 0,12593874 ! regulation of blood pressure GO:0008217 48 47 1,000 0,0487994 0,13072281 ! actin filament organization GO:0007015 50 48 1,000 0,0506801 0,13556374 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,0506801 0,13536727 ! respiratory burst GO:0045730 7 7 0,000 0,0517444 0,13801002 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,0517444 0,13781058 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,0517444 0,13761172 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,0517444 0,13741343 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,0517444 0,13721572 ! regulation of chemokine production GO:0032642 7 7 0,000 0,0517444 0,13701857 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,0517444 0,13682198 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,0517444 0,13662596 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,0517444 0,13643051 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,0517444 0,1362356 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,0517444 0,13604126 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,0517444 0,13584747 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,0517444 0,13565423 ! axis specification GO:0009798 7 7 0,000 0,0517444 0,13546154 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,0517444 0,13526939 ! visual behavior GO:0007632 7 7 0,000 0,0517444 0,13507779 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,0517444 0,13488674 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,0517444 0,13469622 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,0517444 0,13450624 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,0517444 0,13431679 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,0517444 0,13412788 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,0517444 0,1339395 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,0517444 0,13375165 ! digestive system development GO:0055123 7 7 0,000 0,0517444 0,13356432 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,0517444 0,13337751 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,0517444 0,13319123 ! protein targeting to ER GO:0045047 8 7 0,000 0,0517444 0,13300547 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,0517444 0,13282023 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,0517444 0,1326355 ! endoderm development GO:0007492 7 7 0,000 0,0517444 0,13245128 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,0517444 0,13226758 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,0517444 0,13208438 ! response to hexose stimulus GO:0009746 7 7 0,000 0,0517444 0,13190169 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,0517444 0,13171951 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,0517444 0,13153783 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,0517444 0,13135664 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,0517444 0,13117596 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,0517444 0,13099577 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,0517444 0,13081608 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,0517444 0,13063688 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,0517444 0,13045817 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,0517444 0,13027995 ! response to X-ray GO:0010165 7 7 0,000 0,0517444 0,13010221 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,0517444 0,12992496 ! UV protection GO:0009650 7 7 0,000 0,0517444 0,12974819 ! DNA integration GO:0015074 7 7 0,000 0,0517444 0,12957191 ! myofibril assembly GO:0030239 7 7 0,000 0,0517444 0,1293961 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,0517444 0,12922076 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,0517444 0,1290459 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,0517444 0,12887152 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,0517444 0,1286976 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,0517444 0,12852416 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,0517444 0,12835118 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,0517444 0,12817866 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,0517444 0,12800661 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,0517444 0,12783502 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,0517444 0,12766389 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,0517444 0,12749321 ! axon cargo transport GO:0008088 7 7 0,000 0,0517444 0,12732299 ! eating behavior GO:0042755 7 7 0,000 0,0517444 0,12715323 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,0517444 0,12698392 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,0517444 0,12681506 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,0517444 0,12664664 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,0517444 0,12647868 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,0517444 0,12631116 ! cranial nerve development GO:0021545 7 7 0,000 0,0517444 0,12614408 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,0517444 0,12597744 ! induction of an organ GO:0001759 7 7 0,000 0,0517444 0,12581124 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,0517444 0,12564549 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,0517444 0,12548016 ! autonomic nervous system development GO:0048483 7 7 0,000 0,0517444 0,12531527 ! intracellular lipid transport GO:0032365 7 7 0,000 0,0517444 0,12515082 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,0517444 0,12498679 ! platelet activation GO:0030168 8 7 0,000 0,0517444 0,1248232 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,0517444 0,12466003 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,0517444 0,12449729 ! natural killer cell activation GO:0030101 7 7 0,000 0,0517444 0,12433497 ! response to gamma radiation GO:0010332 8 7 0,000 0,0517444 0,12417308 ! NADP metabolic process GO:0006739 7 7 0,000 0,0517444 0,1240116 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,0517444 0,12385055 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,0517444 0,12368991 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,0517444 0,12352969 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,0517444 0,12336989 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,0517444 0,1232105 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,0517444 0,12305151 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,0517444 0,12289294 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,0517444 0,12273478 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,0517444 0,12257702 ! cell-cell recognition GO:0009988 8 7 0,000 0,0517444 0,12241967 ! hormone catabolic process GO:0042447 7 7 0,000 0,0517444 0,12226272 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,0517444 0,12210618 ! oxygen transport GO:0015671 7 7 0,000 0,0517444 0,12195003 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,0517444 0,12179428 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,0517444 0,12163893 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,0517444 0,12148398 ! regulation of axon extension GO:0030516 7 7 0,000 0,0517444 0,12132942 ! cell killing GO:0001906 7 7 0,000 0,0517444 0,12117525 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,0517444 0,12102148 ! adult feeding behavior GO:0008343 7 7 0,000 0,0517444 0,12086809 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,0517444 0,12071509 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,0517444 0,12056248 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,0517444 0,12041026 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,0517444 0,12025842 ! response to cold GO:0009409 7 7 0,000 0,0517444 0,12010696 ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 0,05258675 0,12190865 ! regulation of defense response GO:0031347 50 50 1,000 0,05451888 0,12622901 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,05451888 0,12607063 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,05647601 0,13043268 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,05647601 0,13026944 ! positive regulation of immune response GO:0050778 51 51 1,000 0,05647601 0,1301066 ! rRNA metabolic process GO:0016072 51 51 1,000 0,05647601 0,12994417 GO:0006364|rRNA processing, ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,05647601 0,12978215 GO:0051325|interphase, ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,05845766 0,1341687 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,05845766 0,13400183 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,05845766 0,13383537 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05891874 0,13472363 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05891874 0,13455669 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05891874 0,13439016 ! positive regulation of translation GO:0045727 8 8 0,000 0,05891874 0,13422404 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05891874 0,13405833 ! superoxide anion generation GO:0042554 8 8 0,000 0,05891874 0,13389303 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05891874 0,13372814 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05891874 0,13356365 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05891874 0,13339957 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05891874 0,13323588 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05891874 0,13307261 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05891874 0,13290973 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,05891874 0,13274724 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05891874 0,13258516 ! zinc ion transport GO:0006829 8 8 0,000 0,05891874 0,13242347 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05891874 0,13226218 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05891874 0,13210127 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05891874 0,13194076 ! lipid localization GO:0010876 8 8 0,000 0,05891874 0,13178064 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05891874 0,1316209 ! response to cAMP GO:0051591 8 8 0,000 0,05891874 0,13146156 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05891874 0,13130259 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05891874 0,13114402 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05891874 0,13098582 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05891874 0,13082801 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05891874 0,13067057 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05891874 0,13051352 ! sensory perception of taste GO:0050909 8 8 0,000 0,05891874 0,13035684 ! organelle fusion GO:0048284 8 8 0,000 0,05891874 0,13020053 ! pancreas development GO:0031016 8 8 0,000 0,05891874 0,13004461 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05891874 0,12988905 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05891874 0,12973387 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05891874 0,12957905 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05891874 0,12942461 ! sperm motility GO:0030317 8 8 0,000 0,05891874 0,12927053 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05891874 0,12911682 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05891874 0,12896347 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05891874 0,12881049 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05891874 0,12865787 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05891874 0,12850562 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05891874 0,12835372 ! Golgi organization GO:0007030 8 8 0,000 0,05891874 0,12820218 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05891874 0,128051 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05891874 0,12790017 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,05891874 0,1277497 ! fructose metabolic process GO:0006000 8 8 0,000 0,05891874 0,12759958 ! mannose metabolic process GO:0006013 9 8 0,000 0,05891874 0,12744982 ! NAD metabolic process GO:0019674 8 8 0,000 0,05891874 0,12730041 ! sex determination GO:0007530 8 8 0,000 0,05891874 0,12715134 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05891874 0,12700263 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,05891874 0,12685426 ! response to fungus GO:0009620 8 8 0,000 0,05891874 0,12670624 ! stem cell differentiation GO:0048863 8 8 0,000 0,05891874 0,12655856 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05891874 0,12641123 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05891874 0,12626424 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05891874 0,12611759 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05891874 0,12597128 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05891874 0,12582531 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05891874 0,12567968 ! vasoconstriction GO:0042310 8 8 0,000 0,05891874 0,12553439 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05891874 0,12538943 ! muscle cell development GO:0055001 8 8 0,000 0,05891874 0,1252448 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05891874 0,12510051 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05891874 0,12495655 ! sensory perception of pain GO:0019233 8 8 0,000 0,05891874 0,12481293 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05891874 0,12466963 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05891874 0,12452666 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05891874 0,12438402 ! chromatin silencing GO:0006342 8 8 0,000 0,05891874 0,1242417 ! tissue regeneration GO:0042246 8 8 0,000 0,05891874 0,12409971 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05891874 0,12395804 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,05891874 0,1238167 ! water homeostasis GO:0030104 8 8 0,000 0,05891874 0,12367568 ! cofactor transport GO:0051181 8 8 0,000 0,05891874 0,12353498 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05891874 0,1233946 ! acid secretion GO:0046717 8 8 0,000 0,05891874 0,12325454 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,05891874 0,12311479 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05891874 0,12297536 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05891874 0,12283625 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05891874 0,12269745 ! regulation of RNA stability GO:0043487 8 8 0,000 0,05891874 0,12255897 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,05891874 0,1224208 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05891874 0,12228293 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,05891874 0,12214538 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05891874 0,12200814 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05891874 0,12187121 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05891874 0,12173458 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05891874 0,12159826 ! developmental induction GO:0031128 8 8 0,000 0,05891874 0,12146224 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05891874 0,12132653 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05891874 0,12119112 ! actin filament polymerization GO:0030041 9 8 0,000 0,05891874 0,12105602 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05891874 0,12092121 ! peptide hormone processing GO:0016486 8 8 0,000 0,05891874 0,1207867 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05891874 0,1206525 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05891874 0,12051859 ! response to virus GO:0009615 54 54 1,000 0,06249269 0,12768739 ! hormone metabolic process GO:0042445 55 54 1,000 0,06249269 0,12754599 ! sulfur metabolic process GO:0006790 55 54 1,000 0,06249269 0,1274049 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,06249269 0,12726412 ! in utero embryonic development GO:0001701 55 55 1,000 0,06454515 0,13129879 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,06454515 0,13115403 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,06454515 0,13100959 ! lactation GO:0007595 10 9 0,000 0,06603985 0,13389597 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06603985 0,13374884 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06603985 0,13360202 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06603985 0,13345553 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06603985 0,13330935 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06603985 0,1331635 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,06603985 0,13301797 ! viral genome replication GO:0019079 9 9 0,000 0,06603985 0,13287275 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06603985 0,13272785 ! copper ion transport GO:0006825 9 9 0,000 0,06603985 0,13258327 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06603985 0,132439 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06603985 0,13229504 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06603985 0,1321514 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06603985 0,13200807 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06603985 0,13186505 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06603985 0,13172234 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06603985 0,13157994 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06603985 0,13143784 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06603985 0,13129605 ! phospholipid efflux GO:0033700 9 9 0,000 0,06603985 0,13115457 ! response to alkaloid GO:0043279 10 9 0,000 0,06603985 0,13101339 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06603985 0,13087252 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06603985 0,13073194 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,06603985 0,13059167 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06603985 0,1304517 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06603985 0,13031203 ! response to ethanol GO:0045471 9 9 0,000 0,06603985 0,13017266 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,06603985 0,13003359 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,06603985 0,12989481 ! methionine metabolic process GO:0006555 9 9 0,000 0,06603985 0,12975633 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06603985 0,12961815 ! cerebral cortex development GO:0021987 9 9 0,000 0,06603985 0,12948026 ! response to osmotic stress GO:0006970 9 9 0,000 0,06603985 0,12934266 ! pigmentation during development GO:0048066 9 9 0,000 0,06603985 0,12920535 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06603985 0,12906834 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06603985 0,12893161 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06603985 0,12879517 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06603985 0,12865903 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06603985 0,12852317 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,06603985 0,1283876 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,06603985 0,12825231 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,06603985 0,12811731 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06603985 0,12798259 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06603985 0,12784815 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06603985 0,127714 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06603985 0,12758013 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,06603985 0,12744653 ! DNA replication initiation GO:0006270 9 9 0,000 0,06603985 0,12731322 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06603985 0,12718019 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,06603985 0,12704743 ! regulation of cellular pH GO:0030641 9 9 0,000 0,06603985 0,12691495 ! histone acetylation GO:0016573 9 9 0,000 0,06603985 0,12678275 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,06603985 0,12665082 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06603985 0,12651917 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06603985 0,12638779 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06603985 0,12625668 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06603985 0,12612584 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06603985 0,12599528 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,06603985 0,12586498 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06603985 0,12573496 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,06603985 0,1256052 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06603985 0,12547571 ! collagen catabolic process GO:0030574 9 9 0,000 0,06603985 0,12534649 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06603985 0,12521753 ! purine base metabolic process GO:0006144 9 9 0,000 0,06603985 0,12508884 ! gas transport GO:0015669 9 9 0,000 0,06603985 0,12496041 ! cholesterol efflux GO:0033344 9 9 0,000 0,06603985 0,12483225 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06603985 0,12470434 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06603985 0,1245767 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06603985 0,12444933 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06603985 0,12432221 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,06603985 0,12419535 ! defense response to virus GO:0051607 9 9 0,000 0,06603985 0,12406875 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06603985 0,1239424 ! actin filament-based movement GO:0030048 9 9 0,000 0,06603985 0,12381632 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06603985 0,12369049 ! reproductive developmental process GO:0003006 56 56 1,000 0,0666203 0,12465097 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,07297749 0,13640722 ! regulation of cell development GO:0060284 60 59 1,000 0,07297749 0,13626901 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,0731081 0,13637472 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,0731081 0,13623683 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,0731081 0,13609921 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,0731081 0,13596188 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,0731081 0,13582482 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,0731081 0,13568804 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,0731081 0,13555153 ! neuron maturation GO:0042551 10 10 0,000 0,0731081 0,1354153 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,0731081 0,13527934 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,0731081 0,13514365 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,0731081 0,13500824 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,0731081 0,13487309 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,0731081 0,13473822 ! hormone secretion GO:0046879 10 10 0,000 0,0731081 0,13460362 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,0731081 0,13446928 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,0731081 0,13433521 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,0731081 0,13420141 ! inositol metabolic process GO:0006020 10 10 0,000 0,0731081 0,13406788 ! cAMP metabolic process GO:0046058 10 10 0,000 0,0731081 0,13393461 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,0731081 0,13380161 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,0731081 0,13366887 ! glial cell development GO:0021782 10 10 0,000 0,0731081 0,13353639 ! phototransduction GO:0007602 11 10 0,000 0,0731081 0,13340418 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,0731081 0,13327223 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,0731081 0,13314053 ! fat cell differentiation GO:0045444 10 10 0,000 0,0731081 0,1330091 ! myoblast differentiation GO:0045445 10 10 0,000 0,0731081 0,13287793 ! centrosome cycle GO:0007098 10 10 0,000 0,0731081 0,13274701 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,0731081 0,13261636 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,0731081 0,13248596 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,0731081 0,13235582 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,0731081 0,13222593 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,0731081 0,13209629 ! protein polyubiquitination GO:0000209 10 10 0,000 0,0731081 0,13196691 ! glutamate metabolic process GO:0006536 11 10 0,000 0,0731081 0,13183779 ! plasma membrane organization GO:0007009 10 10 0,000 0,0731081 0,13170892 ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,0731081 0,13158029 ! lysosomal transport GO:0007041 10 10 0,000 0,0731081 0,13145192 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,0731081 0,1313238 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,0731081 0,13119593 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,0731081 0,13106831 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,0731081 0,13094093 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,0731081 0,13081381 ! neuromuscular junction development GO:0007528 10 10 0,000 0,0731081 0,13068693 ! embryo implantation GO:0007566 11 10 0,000 0,0731081 0,13056029 ! regulation of protein binding GO:0043393 11 10 0,000 0,0731081 0,1304339 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,0731081 0,13030776 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,0731081 0,13018186 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,0731081 0,1300562 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,0731081 0,12993078 ! cytolysis GO:0019835 10 10 0,000 0,0731081 0,12980561 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,0731081 0,12968067 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,0731081 0,12955598 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,0731081 0,12943153 ! histone deacetylation GO:0016575 10 10 0,000 0,0731081 0,12930731 ! mRNA splice site selection GO:0006376 11 10 0,000 0,0731081 0,12918334 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,0731081 0,1290596 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,0731081 0,1289361 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,0731081 0,12881283 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,0731081 0,1286898 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,0731081 0,128567 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,0731081 0,12844444 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,0731081 0,12832211 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,0731081 0,12820002 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,0731081 0,12807816 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,0731081 0,12795652 ! nerve development GO:0021675 10 10 0,000 0,0731081 0,12783512 ! gut development GO:0048565 10 10 0,000 0,0731081 0,12771395 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,0731081 0,12759301 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,0731081 0,1274723 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0731081 0,12735181 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,0731081 0,12723156 ! protein stabilization GO:0050821 10 10 0,000 0,0731081 0,12711153 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,07513902 0,13051952 ! protein polymerization GO:0051258 65 60 1,000 0,07513902 0,13039662 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,07732107 0,13405713 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,07732107 0,13393113 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,07952322 0,13761623 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,07952322 0,13748714 ! protein secretion GO:0009306 11 11 0,000 0,08012387 0,13839578 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,08012387 0,13826619 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,08012387 0,13813685 ! negative regulation of defense response GO:0031348 11 11 0,000 0,08012387 0,13800775 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,08012387 0,13787889 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,08012387 0,13775027 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,08012387 0,1376219 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,08012387 0,13749376 ! signal complex assembly GO:0007172 11 11 0,000 0,08012387 0,13736586 ! microtubule-based transport GO:0010970 11 11 0,000 0,08012387 0,13723819 ! endothelial cell migration GO:0043542 11 11 0,000 0,08012387 0,13711077 ! peroxisomal transport GO:0043574 11 11 0,000 0,08012387 0,13698358 ! protein amino acid methylation GO:0006479 11 11 0,000 0,08012387 0,13685662 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,08012387 0,1367299 ! heart contraction GO:0060047 11 11 0,000 0,08012387 0,13660342 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,08012387 0,13647717 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,08012387 0,13635115 ! T cell proliferation GO:0042098 11 11 0,000 0,08012387 0,13622536 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,08012387 0,13609981 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,08012387 0,13597449 ! spinal cord development GO:0021510 11 11 0,000 0,08012387 0,1358494 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,08012387 0,13572454 ! smooth muscle contraction GO:0006939 11 11 0,000 0,08012387 0,1355999 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,08012387 0,1354755 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,08012387 0,13535132 ! digestive system process GO:0022600 11 11 0,000 0,08012387 0,13522738 ! fucose metabolic process GO:0006004 11 11 0,000 0,08012387 0,13510365 ! membrane budding GO:0006900 11 11 0,000 0,08012387 0,13498016 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,08012387 0,13485689 ! monoamine transport GO:0015844 11 11 0,000 0,08012387 0,13473385 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,08012387 0,13461103 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,08012387 0,13448843 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,08012387 0,13436606 ! body fluid secretion GO:0007589 11 11 0,000 0,08012387 0,1342439 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,08012387 0,13412198 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,08012387 0,13400027 ! intermediate filament-based process GO:0045103 11 11 0,000 0,08012387 0,13387878 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,08012387 0,13375751 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,08012387 0,13363647 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,08012387 0,13351564 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,08012387 0,13339503 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,08012387 0,13327463 ! oogenesis GO:0048477 11 11 0,000 0,08012387 0,13315446 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,08012387 0,1330345 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,08012387 0,13291476 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,08012387 0,13279523 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,08012387 0,13267592 ! muscle maintenance GO:0046716 12 11 0,000 0,08012387 0,13255682 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,08012387 0,13243793 ! steroid catabolic process GO:0006706 11 11 0,000 0,08012387 0,13231926 ! endocrine process GO:0050886 11 11 0,000 0,08012387 0,1322008 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,08012387 0,13208255 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,08012387 0,13196452 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,08012387 0,13184669 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,08012387 0,13172908 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,08398617 0,13795589 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,08398617 0,13783304 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,08398617 0,13771042 ! regulation of hormone levels GO:0010817 66 65 1,000 0,08624615 0,14129036 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,08708756 0,14254207 ! translational initiation GO:0006413 12 12 0,000 0,08708756 0,14241559 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,08708756 0,14228933 ! initiation of viral infection GO:0019059 12 12 0,000 0,08708756 0,1421633 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,08708756 0,14203749 ! iron ion transport GO:0006826 13 12 0,000 0,08708756 0,14191191 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08708756 0,14178654 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08708756 0,1416614 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,08708756 0,14153648 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,08708756 0,14141178 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,08708756 0,1412873 ! collagen metabolic process GO:0032963 12 12 0,000 0,08708756 0,14116303 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08708756 0,14103899 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,08708756 0,14091516 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08708756 0,14079155 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08708756 0,14066816 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08708756 0,14054498 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08708756 0,14042202 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,08708756 0,14029927 ! actomyosin structure organization GO:0031032 12 12 0,000 0,08708756 0,14017674 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08708756 0,14005442 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,08708756 0,13993232 GO:0016101|diterpenoid metabolic process, ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08708756 0,13981043 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08708756 0,13968874 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,08708756 0,13956728 ! acute-phase response GO:0006953 12 12 0,000 0,08708756 0,13944602 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08708756 0,13932497 ! vacuolar transport GO:0007034 12 12 0,000 0,08708756 0,13920414 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08708756 0,13908351 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08708756 0,13896309 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08708756 0,13884288 ! osteoblast differentiation GO:0001649 12 12 0,000 0,08708756 0,13872288 ! male gonad development GO:0008584 12 12 0,000 0,08708756 0,13860308 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08708756 0,13848349 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08708756 0,13836411 ! renal system process GO:0003014 12 12 0,000 0,08708756 0,13824493 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08708756 0,13812596 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08708756 0,1380072 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,08708756 0,13788863 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08708756 0,13777027 ! pallium development GO:0021543 13 12 0,000 0,08708756 0,13765212 ! cell fate determination GO:0001709 12 12 0,000 0,08708756 0,13753416 ! somitogenesis GO:0001756 13 12 0,000 0,08708756 0,13741641 ! G1 phase GO:0051318 13 12 0,000 0,08708756 0,13729886 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08708756 0,13718151 ! detection of light stimulus GO:0009583 13 12 0,000 0,08708756 0,13706436 ! synaptogenesis GO:0007416 12 12 0,000 0,08708756 0,13694741 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08708756 0,13683066 ! hormone transport GO:0009914 12 12 0,000 0,08708756 0,13671411 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,08708756 0,13659776 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08708756 0,13648161 ! spermatid differentiation GO:0048515 13 12 0,000 0,08708756 0,13636565 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,08708756 0,13624989 ! neural tube closure GO:0001843 13 12 0,000 0,08708756 0,13613432 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,08708756 0,13601896 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,08708756 0,13590378 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,08708756 0,13578881 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,08852461 0,13791281 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,08852461 0,13779633 ! Golgi vesicle transport GO:0048193 67 67 1,000 0,09082115 0,14125179 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,09082115 0,14113269 ! response to radiation GO:0009314 70 68 1,000 0,09313537 0,14460698 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,09399953 0,14582587 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,09399953 0,14570323 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,09399953 0,14558079 GO:0016444|somatic cell DNA recombination, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,09399953 0,14545855 ! gluconeogenesis GO:0006094 13 13 0,000 0,09399953 0,14533653 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,09399953 0,1452147 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,09399953 0,14509308 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,09399953 0,14497166 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,09399953 0,14485045 ! regeneration GO:0031099 13 13 0,000 0,09399953 0,14472944 ! keratinization GO:0031424 13 13 0,000 0,09399953 0,14460863 ! post-embryonic development GO:0009791 14 13 0,000 0,09399953 0,14448802 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,09399953 0,14436762 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,09399953 0,14424741 ! regulation of innate immune response GO:0045088 13 13 0,000 0,09399953 0,1441274 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,09399953 0,1440076 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,09399953 0,14388799 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,09399953 0,14376858 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,09399953 0,14364937 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,09399953 0,14353036 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,09399953 0,14341154 ! autophagy GO:0006914 13 13 0,000 0,09399953 0,14329292 ! receptor metabolic process GO:0043112 14 13 0,000 0,09399953 0,14317449 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,09399953 0,14305627 ! ureteric bud development GO:0001657 13 13 0,000 0,09399953 0,14293823 ! cell aging GO:0007569 13 13 0,000 0,09399953 0,14282039 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,09399953 0,14270275 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,09399953 0,1425853 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,09399953 0,14246804 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,09399953 0,14235098 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,09399953 0,1422341 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,09399953 0,14211742 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,09399953 0,14200093 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,09399953 0,14188463 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,09399953 0,14176853 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,09399953 0,14165261 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,09399953 0,14153688 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,09399953 0,14142134 ! vasodilation GO:0042311 14 13 0,000 0,09399953 0,14130599 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,09399953 0,14119082 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,09399953 0,14107585 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,09399953 0,14096106 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,09399953 0,14084645 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,09399953 0,14073204 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,09399953 0,14061781 ! immunoglobulin production GO:0002377 13 13 0,000 0,09399953 0,14050376 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,09399953 0,1403899 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,09399953 0,14027623 ! cell-cell junction organization GO:0045216 13 13 0,000 0,09399953 0,14016273 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,09399953 0,14004942 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,09399953 0,1399363 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,09399953 0,13982336 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,09399953 0,1397106 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,09399953 0,13959802 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,09399953 0,13948562 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,09399953 0,1393734 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,09399953 0,13926137 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,09399953 0,13914951 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,09399953 0,13903783 ! blastocyst development GO:0001824 13 13 0,000 0,09399953 0,13892633 ! telomere organization GO:0032200 13 13 0,000 0,09399953 0,13881501 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,09399953 0,13870387 ! regulation of amine transport GO:0051952 13 13 0,000 0,09399953 0,13859291 ! tissue homeostasis GO:0001894 13 13 0,000 0,09399953 0,13848213 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,09399953 0,13837152 ! protein tetramerization GO:0051262 13 13 0,000 0,09399953 0,13826108 ! sensory perception of sound GO:0007605 71 69 1,000 0,09546689 0,1403074 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 1,000 0,09546689 0,1401956 ! muscle tissue development GO:0060537 72 70 1,000 0,09781533 0,14352998 ! ribosome biogenesis GO:0042254 71 71 1,000 0,10018032 0,14688331 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,10018032 0,14676655 ! neuron fate commitment GO:0048663 14 14 0,000 0,10086017 0,1476452 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,10086017 0,14752802 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,10086017 0,14741102 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,10086017 0,14729422 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,10086017 0,14717759 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,10086017 0,14706116 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,10086017 0,1469449 ! protein amino acid acylation GO:0043543 14 14 0,000 0,10086017 0,14682883 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,10086017 0,14671294 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,10086017 0,14659724 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,10086017 0,14648172 ! vesicle docking GO:0048278 14 14 0,000 0,10086017 0,14636638 ! superoxide metabolic process GO:0006801 15 14 0,000 0,10086017 0,14625122 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,10086017 0,14613624 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,10086017 0,14602145 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,10086017 0,14590683 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,10086017 0,14579239 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,10086017 0,14567814 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,10086017 0,14556406 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,10086017 0,14545016 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,10086017 0,14533644 ! lysosome organization GO:0007040 14 14 0,000 0,10086017 0,14522289 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,10086017 0,14510952 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,10086017 0,14499633 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,10086017 0,14488332 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,10086017 0,14477048 ! primary neural tube formation GO:0014020 15 14 0,000 0,10086017 0,14465782 ! peptide cross-linking GO:0018149 14 14 0,000 0,10086017 0,14454533 ! regulation of behavior GO:0050795 14 14 0,000 0,10086017 0,14443302 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,10086017 0,14432089 ! base-excision repair GO:0006284 14 14 0,000 0,10086017 0,14420892 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,10086017 0,14409713 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,10086017 0,14398552 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,10086017 0,14387407 ! formation of primary germ layer GO:0001704 14 14 0,000 0,10086017 0,1437628 GO:0001707|mesoderm formation, ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,10086017 0,1436517 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,10086017 0,14354077 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,10086017 0,14343002 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,10086017 0,14331943 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,10086017 0,14320901 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,10086017 0,14309877 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,10086017 0,14298869 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,10256147 0,14528885 ! sensory organ development GO:0007423 72 72 1,000 0,10256147 0,14517726 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,10256147 0,14506584 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,10766986 0,1521745 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,10766986 0,15205789 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,10766986 0,15194146 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,10766986 0,15182521 ! response to vitamin GO:0033273 15 15 0,000 0,10766986 0,15170913 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,10766986 0,15159323 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,10766986 0,15147751 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,10766986 0,15136197 ! ovarian follicle development GO:0001541 15 15 0,000 0,10766986 0,1512466 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,10766986 0,15113141 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,10766986 0,1510164 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,10766986 0,15090155 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,10766986 0,15078689 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,10766986 0,15067239 ! heme metabolic process GO:0042168 15 15 0,000 0,10766986 0,15055808 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,10766986 0,15044393 ! response to ionizing radiation GO:0010212 16 15 0,000 0,10766986 0,15032996 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,10766986 0,15021616 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,10766986 0,15010253 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,10766986 0,14998907 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,10766986 0,14987579 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,10766986 0,14976267 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,10766986 0,14964973 ! phospholipid transport GO:0015914 15 15 0,000 0,10766986 0,14953696 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,10766986 0,14942435 ! glutathione metabolic process GO:0006749 16 15 0,000 0,10766986 0,14931192 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,10766986 0,14919966 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,10766986 0,14908756 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,10766986 0,14897563 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,10766986 0,14886387 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,10766986 0,14875228 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,10766986 0,14864086 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,10766986 0,1485296 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,10766986 0,14841851 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,10979831 0,15123937 ! response to oxidative stress GO:0006979 76 75 1,000 0,10979831 0,15112642 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,11224051 0,15437259 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,11442895 0,15726514 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,11442895 0,15714795 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,11442895 0,15703094 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,11442895 0,1569141 ! learning GO:0007612 16 16 0,000 0,11442895 0,15679743 ! circadian rhythm GO:0007623 16 16 0,000 0,11442895 0,15668094 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,11442895 0,15656463 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,11442895 0,15644848 ! vacuole organization GO:0007033 16 16 0,000 0,11442895 0,15633251 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,11442895 0,1562167 ! vesicle targeting GO:0006903 17 16 0,000 0,11442895 0,15610107 ! segmentation GO:0035282 17 16 0,000 0,11442895 0,15598561 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,11442895 0,15587033 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,11442895 0,15575521 ! iron ion homeostasis GO:0055072 16 16 0,000 0,11442895 0,15564026 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,11442895 0,15552548 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,11442895 0,15541087 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,11442895 0,15529643 ! cell fate specification GO:0001708 16 16 0,000 0,11442895 0,15518216 ! pentose metabolic process GO:0019321 16 16 0,000 0,11442895 0,15506805 ! fatty acid transport GO:0015908 16 16 0,000 0,11442895 0,15495411 ! cofactor catabolic process GO:0051187 16 16 0,000 0,11442895 0,15484035 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,11442895 0,15472674 ! polyol metabolic process GO:0019751 16 16 0,000 0,11442895 0,15461331 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,11442895 0,15450004 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,11442895 0,15438693 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,11442895 0,15427399 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,11442895 0,15416122 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,11442895 0,15404861 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,11442895 0,15393617 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,11442895 0,15382389 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,1146971 0,15407198 ! regulation of protein modification process GO:0031399 79 78 1,000 0,11716771 0,1572761 ! microtubule-based movement GO:0007018 82 78 1,000 0,11716771 0,15716164 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,12113782 0,16236873 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,12113782 0,16225073 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,12113782 0,1621329 ! myelination GO:0042552 17 17 0,000 0,12113782 0,16201524 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,12113782 0,16189775 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,12113782 0,16178043 ! leukocyte adhesion GO:0007159 17 17 0,000 0,12113782 0,16166329 ! sensory perception of smell GO:0007608 17 17 0,000 0,12113782 0,16154631 ! glucose transport GO:0015758 17 17 0,000 0,12113782 0,1614295 ! cell junction assembly GO:0034329 18 17 0,000 0,12113782 0,16131286 ! tissue remodeling GO:0048771 17 17 0,000 0,12113782 0,16119639 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,12113782 0,16108009 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,12113782 0,16096395 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,12113782 0,16084798 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,12113782 0,16073218 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,12113782 0,16061655 ! neural crest cell development GO:0014032 19 17 0,000 0,12113782 0,16050108 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,12113782 0,16038578 ! negative regulation of cell development GO:0010721 18 17 0,000 0,12113782 0,16027064 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,12113782 0,16015567 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,12113782 0,16004086 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,12113782 0,15992622 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,12113782 0,15981174 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,12113782 0,15969743 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,12113782 0,15958327 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,12113782 0,15946929 ! adult locomotory behavior GO:0008344 17 17 0,000 0,12113782 0,15935546 ! embryonic organ development GO:0048568 17 17 0,000 0,12113782 0,1592418 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,12113782 0,1591283 ! liver development GO:0001889 17 17 0,000 0,12113782 0,15901496 ! gene silencing GO:0016458 17 17 0,000 0,12113782 0,15890178 ! MAPKKK cascade GO:0000165 82 81 1,000 0,12466034 0,16340612 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,12779684 0,16739841 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,12779684 0,16727952 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,12779684 0,1671608 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,12779684 0,16704225 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,12779684 0,16692386 ! membrane docking GO:0022406 18 18 0,000 0,12779684 0,16680564 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,12779684 0,16668759 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,12779684 0,16656971 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,12779684 0,16645199 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,12779684 0,16633444 ! hexose transport GO:0008645 18 18 0,000 0,12779684 0,16621706 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,12779684 0,16609984 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,12779684 0,16598278 ! striated muscle contraction GO:0006941 18 18 0,000 0,12779684 0,16586589 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,12779684 0,16574917 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,12779684 0,16563261 ! ceramide metabolic process GO:0006672 18 18 0,000 0,12779684 0,16551621 GO:0046519|sphingoid metabolic process, ! telencephalon development GO:0021537 19 18 0,000 0,12779684 0,16539998 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,12779684 0,16528391 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,12779684 0,165168 ! B cell differentiation GO:0030183 18 18 0,000 0,12779684 0,16505226 ! ensheathment of neurons GO:0007272 18 18 0,000 0,12779684 0,16493667 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,12779684 0,16482125 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,12779684 0,16470599 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,12779684 0,16459089 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,12971943 0,16695035 ! ncRNA processing GO:0034470 83 83 1,000 0,12971943 0,16683385 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,13440636 0,17274123 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,13440636 0,17262085 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,13440636 0,17250064 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,13440636 0,1723806 ! glial cell differentiation GO:0010001 19 19 0,000 0,13440636 0,17226073 ! regulation of pH GO:0006885 19 19 0,000 0,13440636 0,17214102 ! feeding behavior GO:0007631 19 19 0,000 0,13440636 0,17202148 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,13440636 0,1719021 ! peroxisome organization GO:0007031 19 19 0,000 0,13440636 0,17178289 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,13440636 0,17166384 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,13440636 0,17154496 ! metanephros development GO:0001656 19 19 0,000 0,13440636 0,17142625 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,13440636 0,17130769 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,13440636 0,1711893 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,13440636 0,17107108 ! peripheral nervous system development GO:0007422 19 19 0,000 0,13440636 0,17095302 ! regulation of protein stability GO:0031647 19 19 0,000 0,13440636 0,17083512 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,13440636 0,17071738 ! eye morphogenesis GO:0048592 19 19 0,000 0,13440636 0,17059981 ! regulation of cell shape GO:0008360 21 19 0,000 0,13440636 0,1704824 ! placenta development GO:0001890 19 19 0,000 0,13440636 0,17036515 ! response to heat GO:0009408 19 19 0,000 0,13440636 0,17024806 ! vesicle localization GO:0051648 20 19 0,000 0,13440636 0,17013113 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,13482669 0,17054605 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,13482669 0,17042908 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,1373976 0,17355982 GO:0006644|phospholipid metabolic process, ! regulation of muscle development GO:0048634 21 20 0,000 0,14096676 0,17794639 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,14096676 0,17782459 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,14096676 0,17770296 ! negative regulation of binding GO:0051100 21 20 0,000 0,14096676 0,1775815 ! organic ether metabolic process GO:0018904 20 20 0,000 0,14096676 0,1774602 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,14096676 0,17733907 ! nucleus organization GO:0006997 20 20 0,000 0,14096676 0,1772181 ! phagocytosis GO:0006909 21 20 0,000 0,14096676 0,1770973 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,14096676 0,17697666 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,14096676 0,17685618 ! protein targeting to membrane GO:0006612 22 20 0,000 0,14096676 0,17673587 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,14096676 0,17661573 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,14096676 0,17649574 ! lipid oxidation GO:0034440 20 20 0,000 0,14096676 0,17637592 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,14096676 0,17625626 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,14096676 0,17613677 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,14096676 0,17601743 ! RNA modification GO:0009451 20 20 0,000 0,14096676 0,17589826 ! single fertilization GO:0007338 21 20 0,000 0,14096676 0,17577925 ! regulation of B cell activation GO:0050864 20 20 0,000 0,14096676 0,1756604 ! chemotaxis GO:0006935 90 89 1,000 0,14517572 0,180783 GO:0042330|taxis, ! mRNA catabolic process GO:0006402 21 21 0,000 0,14747838 0,18352644 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,14747838 0,1834026 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,14747838 0,18327893 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,14747838 0,18315543 ! Notch signaling pathway GO:0007219 22 21 0,000 0,14747838 0,18303209 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,14747838 0,18290892 ! ear morphogenesis GO:0042471 21 21 0,000 0,14747838 0,18278591 ! organic anion transport GO:0015711 21 21 0,000 0,14747838 0,18266307 ! cholesterol transport GO:0030301 21 21 0,000 0,14747838 0,1825404 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,14747838 0,18241789 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,14747838 0,18229554 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,14747838 0,18217336 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,14747838 0,18205134 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,14747838 0,18192949 ! regulation of proteolysis GO:0030162 21 21 0,000 0,14747838 0,18180779 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,14747838 0,18168626 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,14747838 0,1815649 ! brain development GO:0007420 91 90 1,000 0,14778922 0,18182612 ! DNA replication GO:0006260 91 91 1,000 0,15041262 0,18493026 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,15304564 0,18804208 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,15394158 0,18901688 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,15394158 0,18889104 ! regulation of ion transport GO:0043269 22 22 0,000 0,15394158 0,18876536 ! cell junction organization GO:0034330 23 22 0,000 0,15394158 0,18863985 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,15394158 0,18851451 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,15394158 0,18838934 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,15394158 0,18826433 ! ovulation cycle process GO:0022602 22 22 0,000 0,15394158 0,18813948 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,15394158 0,1880148 ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,15394158 0,18789029 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,15394158 0,18776594 ! male sex differentiation GO:0046661 22 22 0,000 0,15394158 0,18764176 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,15394158 0,18751774 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,15394158 0,18739388 ! detection of external stimulus GO:0009581 23 22 0,000 0,15394158 0,18727019 ! neuron migration GO:0001764 22 22 0,000 0,15394158 0,18714666 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,15394158 0,1870233 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,15394158 0,18690009 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,15394158 0,18677705 ! aerobic respiration GO:0009060 22 22 0,000 0,15394158 0,18665417 ! cytokine production GO:0001816 22 22 0,000 0,15394158 0,18653145 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,16035672 0,19417703 ! viral infectious cycle GO:0019058 23 23 0,000 0,16035672 0,19404954 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,16035672 0,19392221 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,16035672 0,19379505 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,16035672 0,19366805 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,16035672 0,19354122 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,16035672 0,19341456 ! endocrine system development GO:0035270 23 23 0,000 0,16035672 0,19328806 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,16035672 0,19316173 ! female gonad development GO:0008585 23 23 0,000 0,16035672 0,19303556 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,16035672 0,19290956 ! lipid homeostasis GO:0055088 23 23 0,000 0,16035672 0,19278372 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,16035672 0,19265805 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,16035672 0,19253254 ! cell projection assembly GO:0030031 25 23 0,000 0,16035672 0,19240719 ! mitochondrial transport GO:0006839 24 24 0,000 0,16672415 0,19991712 ! regulation of action potential GO:0001508 24 24 0,000 0,16672415 0,19978713 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,16672415 0,19965732 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,16672415 0,19952767 ! T cell differentiation GO:0030217 24 24 0,000 0,16672415 0,19939819 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,16672415 0,19926888 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,16672415 0,19913974 ! ovulation cycle GO:0042698 24 24 0,000 0,16672415 0,19901076 ! fertilization GO:0009566 25 24 0,000 0,16672415 0,19888195 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,16672415 0,19875331 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,16672415 0,19862483 ! glucan metabolic process GO:0044042 25 24 0,000 0,16672415 0,19849652 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! endocytosis GO:0006897 99 98 1,000 0,16902981 0,20111165 GO:0010324|membrane invagination, ! blood circulation GO:0008015 99 98 1,000 0,16902981 0,2009819 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 1,000 0,16902981 0,20085232 ! negative regulation of secretion GO:0051048 26 25 0,000 0,17304421 0,20549 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,17304421 0,20535769 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,17304421 0,20522554 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,17304421 0,20509356 ! cellular component disassembly GO:0022411 26 25 0,000 0,17304421 0,20496175 ! endosome transport GO:0016197 25 25 0,000 0,17304421 0,20483011 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,17304421 0,20469864 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,17304421 0,20456734 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,17304421 0,20443621 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,17304421 0,20430524 ! excretion GO:0007588 25 25 0,000 0,17304421 0,20417445 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,17304421 0,20404382 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,17304421 0,20391335 ! gastrulation GO:0007369 25 25 0,000 0,17304421 0,20378306 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,17304421 0,20365293 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,17304421 0,20352297 ! muscle organ development GO:0007517 102 100 1,000 0,1744222 0,20501282 ! hemopoiesis GO:0030097 104 100 1,000 0,1744222 0,20488216 ! positive regulation of binding GO:0051099 27 26 0,000 0,17931726 0,2104979 ! positive regulation of defense response GO:0031349 26 26 0,000 0,17931726 0,21036391 ! glycolysis GO:0006096 26 26 0,000 0,17931726 0,21023009 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,17931726 0,21009644 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,17931726 0,20996296 ! cellular defense response GO:0006968 26 26 0,000 0,17931726 0,20982965 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,17931726 0,20969651 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,17931726 0,20956354 ! double-strand break repair GO:0006302 27 26 0,000 0,17931726 0,20943074 ! regulation of protein secretion GO:0050708 26 26 0,000 0,17931726 0,2092981 ! germ cell development GO:0007281 27 26 0,000 0,17931726 0,20916563 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,17931726 0,20903334 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,17931726 0,2089012 ! synapse organization GO:0050808 26 26 0,000 0,17931726 0,20876924 ! chloride transport GO:0006821 27 27 0,000 0,18554362 0,21588188 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,18554362 0,21574567 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,18554362 0,21560964 ! learning or memory GO:0007611 28 27 0,000 0,18554362 0,21547378 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,18554362 0,21533809 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,18554362 0,21520258 ! peptide metabolic process GO:0006518 29 27 0,000 0,18554362 0,21506723 ! inner ear development GO:0048839 27 27 0,000 0,18554362 0,21493205 ! defense response to bacterium GO:0042742 27 27 0,000 0,18554362 0,21479704 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,18554362 0,2146622 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,18554362 0,21452754 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,19172365 0,22153397 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,19172365 0,22139517 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,19172365 0,22125653 ! carbohydrate transport GO:0008643 28 28 0,000 0,19172365 0,22111808 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,19172365 0,22097979 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,19172365 0,22084168 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,19172365 0,22070374 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,19172365 0,22056597 ! histone modification GO:0016570 28 28 0,000 0,19172365 0,22042837 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,19172365 0,22029095 ! developmental growth GO:0048589 28 28 0,000 0,19172365 0,2201537 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,19172365 0,22001662 ! cartilage development GO:0051216 29 28 0,000 0,19172365 0,2198797 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,19785768 0,22677345 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,19785768 0,2266325 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,19785768 0,22649174 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,19785768 0,22635115 ! tRNA processing GO:0008033 29 29 0,000 0,19785768 0,22621073 ! covalent chromatin modification GO:0016569 29 29 0,000 0,19785768 0,22607049 ! adult behavior GO:0030534 30 29 0,000 0,19785768 0,22593042 ! response to UV GO:0009411 29 29 0,000 0,19785768 0,22579053 ! transition metal ion transport GO:0000041 31 30 0,000 0,20394604 0,23259441 ! RNA catabolic process GO:0006401 30 30 0,000 0,20394604 0,23245056 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,20394604 0,2323069 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,20394604 0,23216341 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,20394604 0,2320201 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,20394604 0,23187697 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,20394604 0,23173401 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,20394604 0,23159123 ! response to temperature stimulus GO:0009266 30 30 0,000 0,20394604 0,23144862 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,20394604 0,23130619 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,20394604 0,23116394 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,20394604 0,23102186 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,20394604 0,23087995 ! vesicle organization GO:0016050 30 30 0,000 0,20394604 0,23073822 ! regulation of translational initiation GO:0006446 31 31 0,000 0,20998908 0,23742937 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,20998908 0,2372838 ! membrane fusion GO:0006944 31 31 0,000 0,20998908 0,23713841 ! B cell activation GO:0042113 31 31 0,000 0,20998908 0,23699319 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,20998908 0,23684815 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,20998908 0,23670329 ! ion transmembrane transport GO:0034220 31 31 0,000 0,20998908 0,23655861 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,20998908 0,2364141 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,20998908 0,23626977 ! digestion GO:0007586 31 31 0,000 0,20998908 0,23612561 ! regulation of DNA replication GO:0006275 32 31 0,000 0,20998908 0,23598163 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,20998908 0,23583783 ! camera-type eye development GO:0043010 31 31 0,000 0,20998908 0,2356942 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,20998908 0,23555075 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,20998908 0,23540747 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,20998908 0,23526436 ! cell redox homeostasis GO:0045454 32 32 0,000 0,21598712 0,24183734 ! muscle fiber development GO:0048747 32 32 0,000 0,21598712 0,24169051 ! glucose catabolic process GO:0006007 32 32 0,000 0,21598712 0,24154385 ! lipid modification GO:0030258 32 32 0,000 0,21598712 0,24139737 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,21598712 0,24125107 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,21598712 0,24110494 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,21598712 0,240959 ! kidney development GO:0001822 32 32 0,000 0,21598712 0,24081323 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,21598712 0,24066763 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,21598712 0,24052221 ! amino acid transport GO:0006865 33 33 0,000 0,22194049 0,24700261 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,22194049 0,24685354 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,22194049 0,24670466 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,22194049 0,24655595 ! response to metal ion GO:0010038 34 34 0,000 0,22784951 0,25296786 ! ear development GO:0043583 34 34 0,000 0,22784951 0,25281557 ! muscle cell differentiation GO:0042692 35 34 0,000 0,22784951 0,25266345 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,22784951 0,25251152 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,22784951 0,25235977 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,22784951 0,2522082 ! secondary metabolic process GO:0019748 34 34 0,000 0,22784951 0,25205682 ! detection of stimulus GO:0051606 36 34 0,000 0,22784951 0,25190561 ! acute inflammatory response GO:0002526 35 35 0,000 0,23371452 0,25823493 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,23371452 0,2580802 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,23371452 0,25792566 ! mesoderm development GO:0007498 35 35 0,000 0,23371452 0,25777131 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,23371452 0,25761714 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,23371452 0,25746316 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,23371452 0,25730935 ! hydrogen transport GO:0006818 36 36 0,000 0,23953583 0,26356091 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,23953583 0,26340366 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,23953583 0,26324659 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,23953583 0,26308971 ! female pregnancy GO:0007565 37 36 0,000 0,23953583 0,26293301 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,23953583 0,26277651 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,23953583 0,26262018 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,23953583 0,26246405 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,23953583 0,2623081 ! gonad development GO:0008406 36 36 0,000 0,23953583 0,26215233 ! regulation of lipase activity GO:0060191 36 36 0,000 0,23953583 0,26199675 ! activation of immune response GO:0002253 36 36 0,000 0,23953583 0,26184136 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,24531375 0,26799837 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,24531375 0,2678396 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,24531375 0,26768102 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,24531375 0,26752263 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,24531375 0,26736443 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,24531375 0,26720641 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,24531375 0,26704858 ! adaptive immune response GO:0002250 37 37 0,000 0,24531375 0,26689094 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,25104862 0,27296909 ! neurotransmitter transport GO:0006836 40 38 0,000 0,25104862 0,27280814 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,25104862 0,27264738 ! exocytosis GO:0006887 40 38 0,000 0,25104862 0,27248681 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,25104862 0,27232643 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,25104862 0,27216624 ! hexose catabolic process GO:0019320 38 38 0,000 0,25104862 0,27200624 ! RNA elongation GO:0006354 38 38 0,000 0,25104862 0,27184642 ! axon guidance GO:0007411 39 38 0,000 0,25104862 0,27168679 ! regulation of neurological system process GO:0031644 38 38 0,000 0,25104862 0,27152735 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,25104862 0,2713681 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,25674074 0,27735825 ! response to unfolded protein GO:0006986 39 39 0,000 0,25674074 0,27719577 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,25674074 0,27703348 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,25674074 0,27687138 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,25674074 0,27670946 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,25674074 0,27654774 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,25674074 0,2763862 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,26239042 0,2823033 ! DNA catabolic process GO:0006308 41 40 0,000 0,26239042 0,28213859 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,26239042 0,28197408 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,26239042 0,28180976 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,26799798 0,28766469 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,26799798 0,28749725 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,26799798 0,28733 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,26799798 0,28716295 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,26799798 0,28699609 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,26799798 0,28682943 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,26799798 0,28666296 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,27356372 0,2924466 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,27356372 0,29227706 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,27356372 0,29210773 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,27356372 0,29193859 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,27356372 0,29176964 ! response to protein stimulus GO:0051789 42 42 0,000 0,27356372 0,29160089 ! forebrain development GO:0030900 43 42 0,000 0,27356372 0,29143233 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,27908795 0,29714563 ! mitochondrion organization GO:0007005 44 43 0,000 0,27908795 0,29697407 ! alcohol catabolic process GO:0046164 43 43 0,000 0,27908795 0,29680271 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,27908795 0,29663154 ! humoral immune response GO:0006959 44 44 0,000 0,28457097 0,3022849 ! vitamin metabolic process GO:0006766 44 44 0,000 0,28457097 0,30211077 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,28457097 0,30193685 ! regulation of DNA binding GO:0051101 47 45 0,000 0,29001309 0,30753402 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,29001309 0,30735717 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,29001309 0,30718053 ! protein processing GO:0016485 45 45 0,000 0,29001309 0,30700409 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,2954146 0,31254254 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,2954146 0,31236323 ! regulation of membrane potential GO:0042391 46 46 0,000 0,2954146 0,31218412 ! sex differentiation GO:0007548 47 47 0,000 0,3007758 0,31766751 ! amine transport GO:0015837 47 47 0,000 0,3007758 0,31748557 ! rhythmic process GO:0048511 47 47 0,000 0,3007758 0,31730383 ! regulation of catabolic process GO:0009894 48 47 0,000 0,3007758 0,31712231 ! calcium ion transport GO:0006816 48 48 0,000 0,30609699 0,32254817 ! DNA recombination GO:0006310 48 48 0,000 0,30609699 0,32236385 ! leukocyte differentiation GO:0002521 50 49 0,000 0,31137845 0,32773871 ! ossification GO:0001503 50 49 0,000 0,31137845 0,32755164 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,31137845 0,32736479 ! divalent metal ion transport GO:0070838 49 49 0,000 0,31137845 0,32717815 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,31137845 0,32699173 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,31137845 0,32680551 ! response to bacterium GO:0009617 50 49 0,000 0,31137845 0,32661951 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,31137845 0,32643372 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,31137845 0,32624814 GO:0002696|positive regulation of leukocyte activation, ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,31662048 0,33155201 ! negative regulation of transport GO:0051051 51 50 0,000 0,31662048 0,33136374 ! chromatin assembly GO:0031497 50 50 0,000 0,31662048 0,33117568 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,31662048 0,33098783 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,31662048 0,3308002 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,31662048 0,33061277 ! transcription initiation GO:0006352 50 50 0,000 0,31662048 0,33042556 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,31662048 0,33023857 ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,32182337 0,33547538 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,32182337 0,33528574 ! protein maturation GO:0051604 51 51 0,000 0,32182337 0,33509631 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,3269874 0,34028108 ! cell fate commitment GO:0045165 52 52 0,000 0,3269874 0,34008904 ! response to light stimulus GO:0009416 53 52 0,000 0,3269874 0,33989723 ! sodium ion transport GO:0006814 53 53 0,000 0,33211287 0,34503045 ! tRNA metabolic process GO:0006399 53 53 0,000 0,33211287 0,34483606 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,33211287 0,3446419 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,33211287 0,34444795 ! regulation of T cell activation GO:0050863 53 53 0,000 0,33211287 0,34425422 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,33720004 0,3493309 ! nucleosome organization GO:0034728 55 55 0,000 0,3422492 0,35436252 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,3422492 0,35416355 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,34726064 0,35914779 ! regulation of nervous system development GO:0051960 57 56 0,000 0,34726064 0,35894636 ! regulation of binding GO:0051098 60 57 0,000 0,35223462 0,36388363 ! ATP metabolic process GO:0046034 57 57 0,000 0,35223462 0,36367978 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,35223462 0,36347615 ! innate immune response GO:0045087 58 58 0,000 0,35717142 0,36836426 ! dephosphorylation GO:0016311 60 59 0,000 0,36207132 0,37320886 ! carboxylic acid transport GO:0046942 59 59 0,000 0,36207132 0,37300024 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,36207132 0,37279186 ! immune effector process GO:0002252 59 59 0,000 0,36207132 0,37258372 ! potassium ion transport GO:0006813 60 60 0,000 0,36693458 0,37737747 ! cellular respiration GO:0045333 62 61 0,000 0,37176147 0,38212849 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,37176147 0,38191549 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,37655226 0,38662162 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,37655226 0,38640635 ! axonogenesis GO:0007409 66 62 0,000 0,37655226 0,38619133 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,37655226 0,38597654 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,37655226 0,38576199 ! regulation of secretion GO:0051046 65 63 0,000 0,38130721 0,39041622 ! glucose metabolic process GO:0006006 63 63 0,000 0,38130721 0,39019944 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,38130721 0,3899829 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,38130721 0,38976661 ! anion transport GO:0006820 65 65 0,000 0,39071066 0,39915729 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,39535968 0,40368304 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,39535968 0,40345952 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,39535968 0,40323624 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,3999739 0,40771676 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! muscle contraction GO:0006936 67 67 0,000 0,3999739 0,40749138 ! striated muscle tissue development GO:0014706 69 67 0,000 0,3999739 0,40726624 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,3999739 0,40704136 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,40455358 0,41147475 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,40455358 0,41124779 ! regulation of translation GO:0006417 69 69 0,000 0,40909897 0,41563914 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,40909897 0,41541014 ! cell part morphogenesis GO:0032990 75 70 0,000 0,41361033 0,41975982 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,41361033 0,4195288 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,4180879 0,42383719 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,4180879 0,42360418 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 0,000 0,4180879 0,42337143 ! secretion by cell GO:0032940 75 72 0,000 0,42253194 0,42763666 ! muscle system process GO:0003012 72 72 0,000 0,42253194 0,42740195 ! electron transport chain GO:0022900 75 74 0,000 0,43132038 0,43605236 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,43132038 0,4358133 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,43566527 0,43996224 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,44425761 0,44839363 ! metal ion homeostasis GO:0055065 78 78 0,000 0,44850553 0,45243332 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,45690605 0,46065528 ! neuron projection development GO:0031175 85 80 0,000 0,45690605 0,46040342 ! lymphocyte activation GO:0046649 82 81 0,000 0,46105912 0,46433441 ! lipid catabolic process GO:0016042 82 81 0,000 0,46105912 0,46408081 ! hexose metabolic process GO:0019318 87 86 0,000 0,48136175 0,48425202 ! male gamete generation GO:0048232 90 88 0,000 0,48927107 0,4919403 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,48927107 0,49167207 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,49318124 0,49533135 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,49706205 0,49895717 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,50091371 0,50254979 ! visual perception GO:0007601 93 92 0,000 0,50473644 0,50610949 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,50473644 0,50583429 ! cofactor metabolic process GO:0051186 95 94 0,000 0,51229594 0,5131312 ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,527077 0,5276496 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,527077 0,52736314 ! anti-apoptosis GO:0006916 100 99 0,000 0,53070307 0,53070307