pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6578-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! mitotic sister chromatid segregation GO:0000070 57 36 5,000 6,158E-08 1,482E-04 ! sister chromatid segregation GO:0000819 58 37 5,000 7,314E-08 8,799E-05 ! chromosome segregation GO:0007059 113 67 6,000 1,337E-07 1,072E-04 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 6,000 1,337E-07 8,039E-05 ! negative regulation of ligase activity GO:0051352 112 68 6,000 1,483E-07 7,134E-05 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 6,000 1,483E-07 5,945E-05 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 6,000 2,209E-07 7,593E-05 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 6,000 4,2E-07 1,263E-04 ! regulation of ligase activity GO:0051340 142 84 6,000 6,404E-07 1,712E-04 ! spindle organization GO:0007051 46 32 4,000 1,141E-06 2,745E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 6,000 1,282E-06 2,803E-04 GO:0010498|proteasomal protein catabolic process, ! carbohydrate homeostasis GO:0033500 53 38 4,000 2,764E-06 5,542E-04 GO:0042593|glucose homeostasis, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 5,000 3,231E-06 5,98E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 3,874E-06 6,657E-04 ! mitotic chromosome condensation GO:0007076 34 19 3,000 4,079E-06 6,543E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 5,000 4,15E-06 6,241E-04 ! positive regulation of ligase activity GO:0051351 124 77 5,000 6,148E-06 8,702E-04 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 5,000 7,139E-06 9,542E-04 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 3,000 7,594E-06 9,616E-04 ! positive regulation of cell cycle GO:0045787 89 48 4,000 8,994E-06 1,082E-03 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 1,075E-05 1,232E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 2,000 1,075E-05 1,176E-03 ! chromosome condensation GO:0030261 45 25 3,000 1,295E-05 1,355E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 2,000 1,606E-05 1,61E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,606E-05 1,546E-03 ! SMAD protein nuclear translocation GO:0007184 20 10 2,000 2,284E-05 2,114E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 2,284E-05 2,036E-03 ! cell cycle arrest GO:0007050 213 100 5,000 2,767E-05 2,377E-03 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 3,128E-05 2,595E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 2,000 4,152E-05 3,33E-03 ! mitotic spindle organization GO:0007052 21 12 2,000 4,152E-05 3,223E-03 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 4,152E-05 3,122E-03 ! detection of bacterium GO:0016045 18 15 2,000 8,477E-05 6,181E-03 ! activation of protein kinase activity GO:0032147 147 79 4,000 1,023E-04 7,239E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 1,039E-04 7,141E-03 ! response to drug GO:0042493 143 82 4,000 1,221E-04 8,161E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 1,256E-04 8,168E-03 ! myoblast differentiation GO:0045445 45 17 2,000 1,256E-04 7,953E-03 ! branching morphogenesis of a tube GO:0048754 97 45 3,000 1,393E-04 8,592E-03 ! patterning of blood vessels GO:0001569 39 18 2,000 1,501E-04 9,027E-03 ! epidermis morphogenesis GO:0048730 40 18 2,000 1,501E-04 8,807E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 1,775E-04 0,01016561 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 1,775E-04 9,929E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 1,775E-04 9,704E-03 ! protein export from nucleus GO:0006611 36 19 2,000 1,775E-04 9,488E-03 ! regulation of cell cycle process GO:0010564 149 90 4,000 1,894E-04 9,907E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,079E-04 0,0106414 ! pancreas development GO:0031016 35 20 2,000 2,079E-04 0,0104197 ! phosphatidylinositol metabolic process GO:0046488 36 21 2,000 2,415E-04 0,01185715 ! collagen fibril organization GO:0030199 59 21 2,000 2,415E-04 0,01162001 ! detection of biotic stimulus GO:0009595 29 21 2,000 2,415E-04 0,01139217 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 2,451E-04 0,01134248 ! calcium-independent cell-cell adhesion GO:0016338 30 22 2,000 2,784E-04 0,01263873 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,784E-04 0,01240468 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 3,357E-04 0,01468415 ! serotonin receptor signaling pathway GO:0007210 10 5 1,000 3,357E-04 0,01442193 ! response to protozoan GO:0001562 10 5 1,000 3,357E-04 0,01416891 ! positive regulation of neurotransmitter secretion GO:0001956 11 5 1,000 3,357E-04 0,01392462 ! smooth muscle tissue development GO:0048745 28 5 1,000 3,357E-04 0,01368861 ! valine metabolic process GO:0006573 10 5 1,000 3,357E-04 0,01346047 ! polyol catabolic process GO:0046174 7 5 1,000 3,357E-04 0,0132398 GO:0019405|alditol catabolic process, ! sister chromatid cohesion GO:0007062 12 5 1,000 3,357E-04 0,01302626 ! positive regulation of transporter activity GO:0032411 8 5 1,000 3,357E-04 0,01281949 GO:0032414|positive regulation of ion transmembrane transporter activity, ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 3,357E-04 0,01261919 ! cellular glucose homeostasis GO:0001678 5 5 1,000 3,357E-04 0,01242505 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,357E-04 0,01223679 ! regulation of centrosome cycle GO:0046605 7 5 1,000 3,357E-04 0,01205415 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,357E-04 0,01187688 ! neural tube patterning GO:0021532 7 5 1,000 3,357E-04 0,01170475 ! muscle cell proliferation GO:0033002 11 5 1,000 3,357E-04 0,01153754 ! regulation of hair follicle development GO:0051797 10 5 1,000 3,357E-04 0,01137504 GO:0042634|regulation of hair cycle, ! secretory granule organization GO:0033363 11 5 1,000 3,357E-04 0,01121706 ! glial cell migration GO:0008347 11 5 1,000 3,357E-04 0,0110634 ! regulation of sensory perception GO:0051931 7 5 1,000 3,357E-04 0,01091389 GO:0051930|regulation of sensory perception of pain, ! stem cell division GO:0017145 11 5 1,000 3,357E-04 0,01076837 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 1,000 3,357E-04 0,01062668 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 3,628E-04 0,01133567 ! regulation of transmembrane transport GO:0034762 38 24 2,000 3,628E-04 0,01119034 ! positive regulation of secretion GO:0051047 95 59 3,000 3,992E-04 0,01215863 ! vasculogenesis GO:0001570 46 25 2,000 4,105E-04 0,01234527 ! regulation of insulin secretion GO:0050796 37 25 2,000 4,105E-04 0,01219286 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 4,62E-04 0,01355682 ! embryonic hemopoiesis GO:0035162 14 6 1,000 5,016E-04 0,01453954 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 5,016E-04 0,01436645 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! establishment of spindle localization GO:0051293 12 6 1,000 5,016E-04 0,01419744 GO:0051653|spindle localization, ! myeloid dendritic cell activation GO:0001773 10 6 1,000 5,016E-04 0,01403235 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 1,000 5,016E-04 0,01387106 ! regulation of mitosis GO:0007088 105 63 3,000 5,131E-04 0,01402877 GO:0051783|regulation of nuclear division, ! fat cell differentiation GO:0045444 50 27 2,000 5,176E-04 0,0139917 ! positive regulation of cell motion GO:0051272 146 64 3,000 5,448E-04 0,0145653 ! regulation of peptide secretion GO:0002791 47 29 2,000 6,41E-04 0,01694868 ! prostate gland development GO:0030850 13 7 1,000 6,995E-04 0,01829347 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 6,995E-04 0,01809677 ! SMAD protein complex assembly GO:0007183 12 7 1,000 6,995E-04 0,01790425 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 6,995E-04 0,01771578 ! positive regulation of neurotransmitter transport GO:0051590 16 7 1,000 6,995E-04 0,01753124 ! regulation of dopamine metabolic process GO:0042053 11 7 1,000 6,995E-04 0,01735051 GO:0042069|regulation of catecholamine metabolic process, ! melanosome organization GO:0032438 9 7 1,000 6,995E-04 0,01717346 ! spindle checkpoint GO:0031577 15 7 1,000 6,995E-04 0,01699999 ! negative regulation of nuclear division GO:0051784 14 7 1,000 6,995E-04 0,01682999 GO:0045839|negative regulation of mitosis, ! dopamine biosynthetic process GO:0042416 18 7 1,000 6,995E-04 0,01666336 ! cell cycle checkpoint GO:0000075 137 69 3,000 7,247E-04 0,01709451 ! myeloid leukocyte activation GO:0002274 49 31 2,000 7,818E-04 0,01826321 ! regulation of caspase activity GO:0043281 122 72 3,000 8,508E-04 0,01968271 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 8,59E-04 0,01968411 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 1,000 9,291E-04 0,02108844 ! regulation of cellular amine metabolic process GO:0033238 12 8 1,000 9,291E-04 0,02089136 ! succinate metabolic process GO:0006105 14 8 1,000 9,291E-04 0,02069792 ! endothelial cell differentiation GO:0045446 17 8 1,000 9,291E-04 0,02050803 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 9,291E-04 0,02032159 ! pigment granule organization GO:0048753 16 8 1,000 9,291E-04 0,02013851 ! regulation of defense response to virus by virus GO:0050690 18 8 1,000 9,291E-04 0,01995871 ! glycine catabolic process GO:0006546 13 8 1,000 9,291E-04 0,01978208 ! macrophage activation GO:0042116 12 8 1,000 9,291E-04 0,01960855 ! protein retention in ER lumen GO:0006621 14 8 1,000 9,291E-04 0,01943804 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 9,291E-04 0,01927047 ! positive regulation of epidermis development GO:0045684 13 8 1,000 9,291E-04 0,01910577 ! behavioral response to nicotine GO:0035095 12 8 1,000 9,291E-04 0,01894386 ! leukocyte chemotaxis GO:0030595 50 33 2,000 9,409E-04 0,01902348 GO:0060326|cell chemotaxis, ! regulation of endopeptidase activity GO:0052548 125 74 3,000 9,43E-04 0,01890658 ! steroid biosynthetic process GO:0006694 131 76 3,000 1,042E-03 0,02071872 ! negative regulation of organelle organization GO:0010639 161 78 3,000 1,148E-03 0,02264075 ! artery development GO:0060840 24 9 1,000 1,19E-03 0,02327653 GO:0048844|artery morphogenesis, ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 1,19E-03 0,02308882 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,19E-03 0,02290411 GO:0006600|creatine metabolic process, ! serine family amino acid catabolic process GO:0009071 16 9 1,000 1,19E-03 0,02272233 ! pyrimidine base metabolic process GO:0006206 17 9 1,000 1,19E-03 0,02254341 ! regulation of amino acid transport GO:0051955 11 9 1,000 1,19E-03 0,02236729 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,204E-03 0,02245241 ! protein import into nucleus GO:0006606 158 80 3,000 1,261E-03 0,02334653 ! response to hypoxia GO:0001666 171 81 3,000 1,321E-03 0,02426195 ! nuclear import GO:0051170 161 81 3,000 1,321E-03 0,02407815 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 1,424E-03 0,02576033 ! response to oxygen levels GO:0070482 176 83 3,000 1,446E-03 0,02596196 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,482E-03 0,0264076 ! positive regulation of heart contraction GO:0045823 16 10 1,000 1,482E-03 0,02621343 ! nucleobase biosynthetic process GO:0046112 24 10 1,000 1,482E-03 0,02602209 ! epithelial cell development GO:0002064 20 10 1,000 1,482E-03 0,02583352 ! salivary gland development GO:0007431 27 10 1,000 1,482E-03 0,02564767 ! midbrain development GO:0030901 13 10 1,000 1,482E-03 0,02546447 ! natural killer cell mediated immunity GO:0002228 18 10 1,000 1,482E-03 0,02528387 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 1,000 1,482E-03 0,02510582 ! response to nicotine GO:0035094 20 10 1,000 1,482E-03 0,02493025 ! tube morphogenesis GO:0035239 176 86 3,000 1,648E-03 0,02754247 ! regulation of hormone secretion GO:0046883 62 40 2,000 1,654E-03 0,02743725 ! protein localization in nucleus GO:0034504 176 87 3,000 1,72E-03 0,02834607 ! gland development GO:0048732 206 88 3,000 1,794E-03 0,02936103 ! DNA methylation GO:0006306 19 11 1,000 1,804E-03 0,02932792 GO:0006305|DNA alkylation, ! thymus development GO:0048538 27 11 1,000 1,804E-03 0,02913109 ! regulation of organic acid transport GO:0032890 18 11 1,000 1,804E-03 0,02893688 ! regulation of embryonic development GO:0045995 27 11 1,000 1,804E-03 0,02874525 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,905E-03 0,03015347 ! epithelial cell differentiation GO:0030855 79 43 2,000 2,039E-03 0,03206581 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 2,000 2,039E-03 0,03185759 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,039E-03 0,03165206 ! virus-host interaction GO:0019048 29 12 1,000 2,157E-03 0,03326063 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 2,157E-03 0,03304878 ! positive regulation of cell growth GO:0030307 22 12 1,000 2,157E-03 0,03283961 ! focal adhesion formation GO:0048041 35 12 1,000 2,157E-03 0,03263307 ! L-glutamate transport GO:0015813 22 12 1,000 2,157E-03 0,03242912 GO:0015800|acidic amino acid transport, ! gland morphogenesis GO:0022612 29 12 1,000 2,157E-03 0,03222769 ! T cell homeostasis GO:0043029 25 12 1,000 2,157E-03 0,03202876 ! leukocyte mediated cytotoxicity GO:0001909 26 12 1,000 2,157E-03 0,03183226 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 2,179E-03 0,03196712 ! leukocyte migration GO:0050900 68 45 2,000 2,325E-03 0,03389784 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,476E-03 0,03589081 ! pigmentation GO:0043473 100 46 2,000 2,476E-03 0,03567589 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,476E-03 0,03546354 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 2,539E-03 0,03614521 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,539E-03 0,03593259 ! exocrine system development GO:0035272 32 13 1,000 2,539E-03 0,03572246 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,539E-03 0,03551477 ! regulation of epidermis development GO:0045682 19 13 1,000 2,539E-03 0,03530948 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 2,539E-03 0,03510655 ! response to virus GO:0009615 160 98 3,000 2,656E-03 0,0365207 ! activation of caspase activity GO:0006919 84 48 2,000 2,797E-03 0,03824247 ! hair follicle morphogenesis GO:0031069 26 14 1,000 2,951E-03 0,04010914 ! palate development GO:0060021 31 14 1,000 2,951E-03 0,03988381 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,951E-03 0,03966099 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 1,000 2,951E-03 0,03944066 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 2,951E-03 0,03922275 ! positive regulation of cell size GO:0045793 27 15 1,000 3,392E-03 0,04483595 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 3,392E-03 0,04459094 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 1,000 3,392E-03 0,0443486 ! dopamine metabolic process GO:0042417 35 15 1,000 3,392E-03 0,04410888 ! cell killing GO:0001906 29 15 1,000 3,392E-03 0,04387173 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,392E-03 0,04363713 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 3,392E-03 0,04340501 ! positive regulation of growth GO:0045927 90 52 2,000 3,514E-03 0,04473387 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 3,861E-03 0,04889563 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 3,861E-03 0,04863963 ! regulation of defense response to virus GO:0050688 27 16 1,000 3,861E-03 0,0483863 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 3,861E-03 0,0481356 ! regulation of dephosphorylation GO:0035303 43 16 1,000 3,861E-03 0,04788747 ! negative regulation of immune response GO:0050777 35 16 1,000 3,861E-03 0,0476419 ! neuron recognition GO:0008038 35 16 1,000 3,861E-03 0,04739883 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,861E-03 0,04715822 ! defense response to virus GO:0051607 37 16 1,000 3,861E-03 0,04692005 ! positive regulation of caspase activity GO:0043280 95 55 2,000 4,119E-03 0,04979483 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 97 55 2,000 4,119E-03 0,04954586 ! nuclear export GO:0051168 97 55 2,000 4,119E-03 0,04929936 ! negative regulation of cell motion GO:0051271 134 55 2,000 4,119E-03 0,0490553 ! skeletal muscle fiber development GO:0048741 111 56 2,000 4,333E-03 0,05135758 ! positive regulation of organelle organization GO:0010638 100 56 2,000 4,333E-03 0,05110583 ! glycine metabolic process GO:0006544 28 17 1,000 4,359E-03 0,05116373 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 1,000 4,359E-03 0,05091536 ! nucleobase metabolic process GO:0009112 37 17 1,000 4,359E-03 0,0506694 ! heart looping GO:0001947 30 17 1,000 4,359E-03 0,05042579 ! neutrophil chemotaxis GO:0030593 27 17 1,000 4,359E-03 0,05018452 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 4,359E-03 0,04994555 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 4,359E-03 0,04970884 ! muscle fiber development GO:0048747 112 57 2,000 4,554E-03 0,05168893 ! positive regulation of cell migration GO:0030335 126 57 2,000 4,554E-03 0,05144625 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,554E-03 0,05120585 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 1,000 4,885E-03 0,05467209 ! cell-substrate junction assembly GO:0007044 54 18 1,000 4,885E-03 0,05441898 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 4,885E-03 0,0541682 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 4,885E-03 0,05391972 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 4,885E-03 0,05367351 ! skin development GO:0043588 36 19 1,000 5,439E-03 0,05948705 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,439E-03 0,05921788 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 5,439E-03 0,05895113 ! cellular pigmentation GO:0033059 36 19 1,000 5,439E-03 0,05868678 ! proximal/distal pattern formation GO:0009954 32 19 1,000 5,439E-03 0,05842478 ! protein import into nucleus, docking GO:0000059 41 20 1,000 6,021E-03 0,06438092 ! positive regulation of ossification GO:0045778 47 20 1,000 6,021E-03 0,06409605 ! response to alkaloid GO:0043279 38 20 1,000 6,021E-03 0,06381369 ! cellular response to starvation GO:0009267 33 20 1,000 6,021E-03 0,06353381 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 1,000 6,021E-03 0,06325637 ! detection of external stimulus GO:0009581 91 63 2,000 6,026E-03 0,06303227 ! glycerol metabolic process GO:0006071 34 21 1,000 6,629E-03 0,06904485 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 6,629E-03 0,06874725 ! inactivation of MAPK activity GO:0000188 39 21 1,000 6,629E-03 0,06845219 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 6,629E-03 0,06815966 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 6,629E-03 0,06786962 ! regulation of vasoconstriction GO:0019229 39 21 1,000 6,629E-03 0,06758204 ! DNA modification GO:0006304 34 21 1,000 6,629E-03 0,06729688 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 6,629E-03 0,06701412 ! actin filament organization GO:0007015 148 66 2,000 6,855E-03 0,06901375 ! extracellular matrix organization GO:0030198 133 66 2,000 6,855E-03 0,0687262 ! negative regulation of cell growth GO:0030308 132 67 2,000 7,146E-03 0,07134577 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 7,264E-03 0,0722203 ! positive regulation of bone remodeling GO:0046852 51 22 1,000 7,264E-03 0,07192309 GO:0034105|positive regulation of tissue remodeling, ! regeneration GO:0031099 41 22 1,000 7,264E-03 0,07162833 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 7,264E-03 0,07133597 ! negative regulation of cell size GO:0045792 134 69 2,000 7,75E-03 0,0757995 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 7,926E-03 0,07720149 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 7,926E-03 0,07689019 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 7,926E-03 0,0765814 ! gluconeogenesis GO:0006094 33 23 1,000 7,926E-03 0,07627507 ! barbed-end actin filament capping GO:0051016 50 23 1,000 7,926E-03 0,07597119 GO:0051693|actin filament capping, ! pyrimidine nucleoside metabolic process GO:0006213 29 23 1,000 7,926E-03 0,07566971 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 8,613E-03 0,08190886 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 8,613E-03 0,08158639 ! leukocyte homeostasis GO:0001776 44 24 1,000 8,613E-03 0,08126644 ! alditol metabolic process GO:0019400 38 24 1,000 8,613E-03 0,08094899 ! regulation of multi-organism process GO:0043900 36 24 1,000 8,613E-03 0,08063402 ! regulation of amine transport GO:0051952 40 24 1,000 8,613E-03 0,08032148 ! phosphoinositide metabolic process GO:0030384 128 72 2,000 8,71E-03 0,08091608 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 9,326E-03 0,08630407 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 9,326E-03 0,0859734 ! response to starvation GO:0042594 42 25 1,000 9,326E-03 0,08564526 ! interaction with host GO:0051701 62 25 1,000 9,326E-03 0,08531961 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 9,326E-03 0,08499643 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,326E-03 0,08467569 ! meiosis GO:0007126 121 74 2,000 9,388E-03 0,08491255 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 2,000 9,738E-03 0,08774699 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 0,01006498 0,09035948 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 0,01006498 0,09002357 ! pyruvate metabolic process GO:0006090 38 26 1,000 0,01006498 0,08969015 ! molting cycle process GO:0022404 50 26 1,000 0,01006498 0,08935919 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! insulin receptor signaling pathway GO:0008286 64 26 1,000 0,01006498 0,08903066 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01006498 0,08870454 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 0,01006498 0,0883808 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01006498 0,08805942 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 0,01006498 0,08774036 ! regulation of response to biotic stimulus GO:0002831 44 26 1,000 0,01006498 0,08742361 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01006498 0,08710914 GO:0045840|positive regulation of mitosis, ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01082877 0,09338361 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01082877 0,09305009 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 0,01082877 0,09271896 ! muscle cell differentiation GO:0042692 159 80 2,000 0,01159999 0,09897012 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 0,01161736 0,09876805 ! negative regulation of protein modification process GO:0031400 60 28 1,000 0,01161736 0,09842027 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 0,01161736 0,09807494 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01161736 0,09773202 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01161736 0,09739149 ! intracellular protein transmembrane transport GO:0065002 153 81 2,000 0,01199533 0,10021102 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01239835 0,10321952 ! negative regulation of protein complex assembly GO:0031333 59 29 1,000 0,01243042 0,10312959 ! catechol metabolic process GO:0009712 54 29 1,000 0,01243042 0,1027752 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01243042 0,10242323 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01243042 0,10207366 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01243042 0,10172647 ! negative regulation of growth GO:0045926 155 84 2,000 0,0132275 0,10788262 ! phenol metabolic process GO:0018958 55 30 1,000 0,01326765 0,10784444 ! cell junction assembly GO:0034329 78 30 1,000 0,01326765 0,10748133 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01326765 0,10712065 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01412874 0,11369143 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 0,01412874 0,11331246 ! regulation of protein transport GO:0051223 154 87 2,000 0,01452929 0,11613781 GO:0070201|regulation of establishment of protein localization, ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01501338 0,11960992 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,01501338 0,11921517 ! hindbrain development GO:0030902 61 32 1,000 0,01501338 0,11882302 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01501338 0,11843343 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01543607 0,12136987 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01685214 0,1320725 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01685214 0,13164369 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01685214 0,13121766 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,01685214 0,13079438 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 1,000 0,01685214 0,13037382 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01685214 0,12995595 ! odontogenesis GO:0042476 66 35 1,000 0,01780566 0,13687037 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01780566 0,13643448 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01780566 0,13600135 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01780566 0,13557097 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01878155 0,14255019 ! cell junction organization GO:0034330 86 36 1,000 0,01878155 0,14210192 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01878155 0,14165646 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01878155 0,14121378 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,01878155 0,14077386 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01878155 0,14033667 ! embryonic organ development GO:0048568 57 36 1,000 0,01878155 0,1399022 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01878155 0,1394704 ! mRNA transport GO:0051028 169 96 2,000 0,01885661 0,13959693 ! detection of stimulus GO:0051606 151 96 2,000 0,01885661 0,13916872 ! regulation of protein localization GO:0032880 176 97 2,000 0,01937673 0,14257009 ! RNA export from nucleus GO:0006405 56 37 1,000 0,01977951 0,14508997 ! meiosis I GO:0007127 65 37 1,000 0,01977951 0,14464896 ! organic anion transport GO:0015711 68 37 1,000 0,01977951 0,14421063 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,01977951 0,14377495 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02044065 0,14813316 GO:0060538|skeletal muscle organ development, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,02079926 0,15027937 ! mammary gland development GO:0030879 86 39 1,000 0,02184052 0,1573302 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,02184052 0,15686056 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,02290299 0,16400177 ! feeding behavior GO:0007631 59 40 1,000 0,02290299 0,16351512 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02290299 0,16303135 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02290299 0,16255043 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,02290299 0,16207234 ! maintenance of protein location GO:0045185 91 40 1,000 0,02290299 0,16159705 ! cytokinesis GO:0000910 72 40 1,000 0,02290299 0,16112455 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,0239864 0,16825447 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,0239864 0,16776536 ! gliogenesis GO:0042063 88 41 1,000 0,0239864 0,16727908 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,0239864 0,16679562 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,0239864 0,16631494 ! polyol metabolic process GO:0019751 66 41 1,000 0,0239864 0,16583702 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,0239864 0,16536185 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02509047 0,17247909 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02509047 0,1719877 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,02509047 0,1714991 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,02621493 0,17867741 ! neural tube development GO:0021915 77 43 1,000 0,02621493 0,17817267 ! phagocytosis GO:0006909 90 43 1,000 0,02621493 0,17767078 ! biopolymer methylation GO:0043414 84 44 1,000 0,0273595 0,18490719 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,0273595 0,18438925 ! maintenance of location in cell GO:0051651 97 44 1,000 0,0273595 0,18387419 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,02852391 0,19116583 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02852391 0,19063481 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,02852391 0,19010674 ! cell growth GO:0016049 84 45 1,000 0,02852391 0,18958158 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02888175 0,19143113 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02888175 0,19090522 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02888175 0,1903822 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02888175 0,18986203 ! neuron fate determination GO:0048664 7 5 0,000 0,02888175 0,18934469 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02888175 0,18883017 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02888175 0,18831843 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02888175 0,18780946 ! polyol transport GO:0015791 12 5 0,000 0,02888175 0,18730324 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02888175 0,18679973 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02888175 0,18629893 ! response to superoxide GO:0000303 10 5 0,000 0,02888175 0,18580081 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02888175 0,18530534 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02888175 0,1848125 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02888175 0,18432228 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02888175 0,18383466 ! female meiosis GO:0007143 7 5 0,000 0,02888175 0,18334961 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02888175 0,18286711 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02888175 0,18238714 ! cobalt ion transport GO:0006824 11 5 0,000 0,02888175 0,18190969 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02888175 0,18143473 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02888175 0,18096224 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02888175 0,18049221 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02888175 0,18002461 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02888175 0,17955943 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02888175 0,17909665 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02888175 0,17863625 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02888175 0,17817821 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02888175 0,17772251 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02888175 0,17726914 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02888175 0,17681807 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02888175 0,17636929 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02888175 0,17592279 ! negative chemotaxis GO:0050919 14 5 0,000 0,02888175 0,17547854 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02888175 0,17503653 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02888175 0,17459674 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02888175 0,17415915 ! behavioral response to pain GO:0048266 9 5 0,000 0,02888175 0,17372375 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02888175 0,17329053 ! Notch receptor processing GO:0007220 8 5 0,000 0,02888175 0,17285946 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02888175 0,17243052 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02888175 0,17200372 ! micturition GO:0060073 9 5 0,000 0,02888175 0,17157902 ! copulation GO:0007620 9 5 0,000 0,02888175 0,17115641 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02888175 0,17073588 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02888175 0,17031741 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02888175 0,16990098 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02888175 0,16948659 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02888175 0,16907421 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02888175 0,16866384 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02888175 0,16825545 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02888175 0,16784904 ! grooming behavior GO:0007625 6 5 0,000 0,02888175 0,16744458 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02888175 0,16704207 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02888175 0,16664149 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02888175 0,16624283 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02888175 0,16584607 ! lymph vessel development GO:0001945 10 5 0,000 0,02888175 0,16545119 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02888175 0,1650582 ! endochondral ossification GO:0001958 16 5 0,000 0,02888175 0,16466706 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! parathyroid gland development GO:0060017 13 5 0,000 0,02888175 0,16427778 ! anagen GO:0042640 6 5 0,000 0,02888175 0,16389033 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02888175 0,16350471 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02888175 0,16312089 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02888175 0,16273888 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02888175 0,16235865 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02888175 0,16198019 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02888175 0,16160349 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02888175 0,16122854 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02888175 0,16085533 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02888175 0,16048384 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02888175 0,16011406 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02888175 0,15974598 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02888175 0,15937959 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02888175 0,15901488 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02888175 0,15865183 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02888175 0,15829044 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02888175 0,15793068 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02888175 0,15757257 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02888175 0,15721607 ! histidine catabolic process GO:0006548 6 5 0,000 0,02888175 0,15686118 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02888175 0,15650789 ! microvillus organization GO:0032528 7 5 0,000 0,02888175 0,15615618 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02888175 0,15580606 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02888175 0,1554575 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02888175 0,15511049 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02888175 0,15476504 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02888175 0,15442111 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02888175 0,15407872 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02888175 0,15373783 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02888175 0,15339846 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02888175 0,15306058 ! muscle cell migration GO:0014812 8 5 0,000 0,02888175 0,15272418 ! mitochondrial fission GO:0000266 8 5 0,000 0,02888175 0,15238926 ! mRNA transcription GO:0009299 9 5 0,000 0,02888175 0,1520558 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02888175 0,1517238 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02888175 0,15139325 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02888175 0,15106413 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02888175 0,15073645 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02888175 0,15041018 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02888175 0,15008532 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02888175 0,14976186 ! response to food GO:0032094 6 5 0,000 0,02888175 0,14943979 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02888175 0,1491191 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02888175 0,14879979 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02888175 0,14848184 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02888175 0,14816525 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02888175 0,14785 ! forebrain neuron development GO:0021884 13 5 0,000 0,02888175 0,1475361 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02888175 0,14722352 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02888175 0,14691226 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02888175 0,14660232 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02888175 0,14629369 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02888175 0,14598635 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02888175 0,1456803 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02888175 0,14537553 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02888175 0,14507203 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02888175 0,14476979 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02888175 0,14446882 ! basic amino acid transport GO:0015802 11 5 0,000 0,02888175 0,14416909 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02888175 0,1438706 ! depyrimidination GO:0045008 10 5 0,000 0,02888175 0,14357335 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02888175 0,14327732 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02888175 0,14298251 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02888175 0,14268891 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02888175 0,14239652 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02888175 0,14210532 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02888175 0,14181531 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02888175 0,14152648 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02888175 0,14123882 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02888175 0,14095234 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02888175 0,14066701 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02888175 0,14038283 ! response to arsenic GO:0046685 10 5 0,000 0,02888175 0,1400998 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02888175 0,13981791 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02888175 0,13953715 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02888175 0,13925752 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02888175 0,138979 ! response to cadmium ion GO:0046686 7 5 0,000 0,02888175 0,1387016 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02888175 0,1384253 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02888175 0,1381501 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02888175 0,13787599 ! decidualization GO:0046697 11 5 0,000 0,02888175 0,13760297 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02888175 0,13733103 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02888175 0,13706016 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02888175 0,13679036 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02888175 0,13652161 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02888175 0,13625392 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02888175 0,13598728 ! embryonic cleavage GO:0040016 6 5 0,000 0,02888175 0,13572168 ! peroxisome fission GO:0016559 5 5 0,000 0,02888175 0,13545712 ! histone demethylation GO:0016577 10 5 0,000 0,02888175 0,13519358 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02888175 0,13493107 ! mitotic recombination GO:0006312 9 5 0,000 0,02888175 0,13466958 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02888175 0,13440909 ! metaphase plate congression GO:0051310 7 5 0,000 0,02888175 0,13414962 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02888175 0,13389114 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02888175 0,13363366 ! enteric nervous system development GO:0048484 8 5 0,000 0,02888175 0,13337716 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02888175 0,13312165 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02888175 0,13286712 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02888175 0,13261355 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02888175 0,13236095 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02888175 0,13210932 ! plasminogen activation GO:0031639 5 5 0,000 0,02888175 0,13185864 ! B cell homeostasis GO:0001782 13 5 0,000 0,02888175 0,1316089 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02888175 0,13136012 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02888175 0,13111227 ! metaphase GO:0051323 8 5 0,000 0,02888175 0,13086535 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02888175 0,13061936 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02888175 0,1303743 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02888175 0,13013015 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02888175 0,12988692 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02888175 0,12964459 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02888175 0,12940317 ! response to redox state GO:0051775 5 5 0,000 0,02888175 0,12916264 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02888175 0,12892301 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02888175 0,12868426 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02888175 0,1284464 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02888175 0,12820941 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02888175 0,1279733 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02888175 0,12773805 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02888175 0,12750367 ! striatum development GO:0021756 9 5 0,000 0,02888175 0,12727015 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02888175 0,12703748 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02888175 0,12680566 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02888175 0,12657468 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02888175 0,12634455 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02888175 0,12611525 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02888175 0,12588678 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02888175 0,12565913 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02888175 0,12543231 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02888175 0,12520631 ! neuroprotection GO:0043526 6 5 0,000 0,02888175 0,12498112 ! neural plate development GO:0001840 8 5 0,000 0,02888175 0,12475673 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02888175 0,12453316 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02888175 0,12431038 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02888175 0,1240884 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02888175 0,1238672 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02888175 0,1236468 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02888175 0,12342718 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02888175 0,12320834 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02888175 0,12299027 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02888175 0,12277297 ! spindle assembly GO:0051225 6 5 0,000 0,02888175 0,12255644 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02888175 0,12234067 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02888175 0,12212566 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02888175 0,12191141 ! drug metabolic process GO:0017144 6 5 0,000 0,02888175 0,1216979 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02888175 0,12148514 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02888175 0,12127313 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02888175 0,12106185 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02888175 0,12085131 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,0297079 0,12409236 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,0297079 0,1238773 ! response to insulin stimulus GO:0032868 95 46 1,000 0,0297079 0,12366298 ! endosome transport GO:0016197 108 47 1,000 0,03091119 0,1284496 ! methylation GO:0032259 90 47 1,000 0,03091119 0,12822814 ! protein homooligomerization GO:0051260 76 47 1,000 0,03091119 0,12800744 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03213353 0,13284066 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,03213353 0,1326128 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,03337464 0,13749896 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03337464 0,13726392 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03455779 0,14188745 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03455779 0,14164573 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03455779 0,14140484 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03455779 0,14116476 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03455779 0,1409255 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03455779 0,14068705 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03455779 0,1404494 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03455779 0,14021255 ! sleep GO:0030431 13 6 0,000 0,03455779 0,13997651 ! response to oxygen radical GO:0000305 11 6 0,000 0,03455779 0,13974125 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03455779 0,13950679 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03455779 0,13927311 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03455779 0,13904021 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03455779 0,13880809 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03455779 0,13857674 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03455779 0,13834616 ! forebrain regionalization GO:0021871 8 6 0,000 0,03455779 0,13811635 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03455779 0,13788731 ! male meiosis GO:0007140 7 6 0,000 0,03455779 0,13765902 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03455779 0,13743148 ! response to zinc ion GO:0010043 9 6 0,000 0,03455779 0,13720469 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03455779 0,13697866 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03455779 0,13675336 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03455779 0,13652881 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03455779 0,13630499 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03455779 0,13608191 ! malate metabolic process GO:0006108 11 6 0,000 0,03455779 0,13585955 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03455779 0,13563792 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03455779 0,13541701 ! protein refolding GO:0042026 15 6 0,000 0,03455779 0,13519682 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03455779 0,13497735 ! opsonization GO:0008228 8 6 0,000 0,03455779 0,13475858 ! mating behavior GO:0007617 7 6 0,000 0,03455779 0,13454053 ! neuron remodeling GO:0016322 15 6 0,000 0,03455779 0,13432317 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03455779 0,13410652 ! equilibrioception GO:0050957 14 6 0,000 0,03455779 0,13389057 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03455779 0,13367531 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03455779 0,13346075 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03455779 0,13324687 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03455779 0,13303367 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03455779 0,13282116 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03455779 0,13260932 ! toxin metabolic process GO:0009404 11 6 0,000 0,03455779 0,13239816 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03455779 0,13218767 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03455779 0,13197785 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03455779 0,13176869 ! nuclear migration GO:0007097 12 6 0,000 0,03455779 0,1315602 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03455779 0,13135236 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03455779 0,13114518 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03455779 0,13093865 ! thymic T cell selection GO:0045061 12 6 0,000 0,03455779 0,13073278 ! protein lipoylation GO:0009249 10 6 0,000 0,03455779 0,13052754 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03455779 0,13032295 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03455779 0,13011901 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03455779 0,1299157 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03455779 0,12971302 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03455779 0,12951097 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03455779 0,12930956 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03455779 0,12910877 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03455779 0,1289086 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03455779 0,12870905 ! hyperosmotic response GO:0006972 9 6 0,000 0,03455779 0,12851012 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03455779 0,1283118 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03455779 0,12811409 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03455779 0,12791699 ! urea metabolic process GO:0019627 7 6 0,000 0,03455779 0,1277205 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03455779 0,12752461 ! neutrophil activation GO:0042119 8 6 0,000 0,03455779 0,12732932 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03455779 0,12713463 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03455779 0,12694053 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03455779 0,12674702 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03455779 0,1265541 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03455779 0,12636177 ! neuron apoptosis GO:0051402 9 6 0,000 0,03455779 0,12617002 ! nucleoside salvage GO:0043174 9 6 0,000 0,03455779 0,12597886 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03455779 0,12578827 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03455779 0,12559826 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03455779 0,12540882 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03455779 0,12521995 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03455779 0,12503165 ! carnitine transport GO:0015879 10 6 0,000 0,03455779 0,12484391 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03455779 0,12465674 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03455779 0,12447013 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03455779 0,12428407 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03455779 0,12409857 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03455779 0,12391363 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03455779 0,12372923 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03455779 0,12354539 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03455779 0,12336208 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03455779 0,12317933 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03455779 0,12299711 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03455779 0,12281543 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03455779 0,12263428 ! neural nucleus development GO:0048857 14 6 0,000 0,03455779 0,12245367 ! response to UV-C GO:0010225 11 6 0,000 0,03455779 0,1222736 ! astrocyte development GO:0014002 15 6 0,000 0,03455779 0,12209405 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03455779 0,12191502 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03455779 0,12173652 ! interaction with symbiont GO:0051702 13 6 0,000 0,03455779 0,12155855 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03455779 0,12138109 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03455779 0,12120415 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03455779 0,12102772 ! response to copper ion GO:0046688 10 6 0,000 0,03455779 0,12085181 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03455779 0,12067641 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03455779 0,12050151 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03455779 0,12032713 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03455779 0,12015324 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03455779 0,11997986 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03455779 0,11980698 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03455779 0,1196346 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03455779 0,11946271 ! hair follicle maturation GO:0048820 7 6 0,000 0,03455779 0,11929131 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03455779 0,11912041 ! Schwann cell development GO:0014044 15 6 0,000 0,03455779 0,11894999 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03455779 0,11878006 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03455779 0,11861062 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03455779 0,11844166 ! subpallium development GO:0021544 10 6 0,000 0,03455779 0,11827318 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03455779 0,11810518 ! histone ubiquitination GO:0016574 8 6 0,000 0,03455779 0,11793765 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03455779 0,1177706 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03455779 0,11760402 ! G2 phase GO:0051319 16 6 0,000 0,03455779 0,11743792 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03455779 0,11727228 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03455779 0,11710711 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03455779 0,1169424 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03455779 0,11677815 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03455779 0,11661437 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03455779 0,11645104 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03455779 0,11628817 ! receptor internalization GO:0031623 10 6 0,000 0,03455779 0,11612576 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03455779 0,1159638 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03455779 0,11580229 ! protein deubiquitination GO:0016579 14 6 0,000 0,03455779 0,11564123 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03455779 0,11548062 ! protein destabilization GO:0031648 9 6 0,000 0,03455779 0,11532045 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03455779 0,11516073 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03455779 0,11500145 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03455779 0,1148426 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03455779 0,1146842 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03455779 0,11452623 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03455779 0,1143687 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03455779 0,1142116 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03455779 0,11405493 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03455779 0,11389869 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03455779 0,11374288 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03455779 0,11358749 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03455779 0,11343253 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03455779 0,11327799 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03455779 0,11312387 ! catecholamine transport GO:0051937 9 6 0,000 0,03455779 0,11297017 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03455779 0,11281689 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03455779 0,11266402 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03455779 0,11251156 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03455779 0,11235952 ! maternal placenta development GO:0001893 12 6 0,000 0,03455779 0,11220789 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03455779 0,11205666 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03455779 0,11190585 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03455779 0,11175544 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03455779 0,11160543 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03455779 0,11145582 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03455779 0,11130662 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03455779 0,11115781 ! regulation of ossification GO:0030278 117 50 1,000 0,03463429 0,11125514 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03463429 0,1111068 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03463429 0,11095885 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,0359122 0,11489994 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,0359122 0,11474736 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,0359122 0,11459517 ! vesicle organization GO:0016050 107 51 1,000 0,0359122 0,11444339 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,03852182 0,12259722 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,03852182 0,12243527 ! cell maturation GO:0048469 100 53 1,000 0,03852182 0,12227375 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03852182 0,12211265 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,03852182 0,12195198 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03985303 0,1260005 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,03985303 0,12583514 ! cell recognition GO:0008037 85 54 1,000 0,03985303 0,12567022 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,03985303 0,12550573 ! tRNA transcription GO:0009304 14 7 0,000 0,04020084 0,12643558 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04020084 0,12627052 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04020084 0,12610589 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04020084 0,12594169 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04020084 0,12577792 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04020084 0,12561457 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04020084 0,12545165 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04020084 0,12528914 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04020084 0,12512706 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04020084 0,1249654 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04020084 0,12480415 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04020084 0,12464332 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04020084 0,12448291 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04020084 0,1243229 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04020084 0,12416331 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04020084 0,12400413 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04020084 0,12384535 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04020084 0,12368698 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04020084 0,12352902 ! glycolipid transport GO:0046836 10 7 0,000 0,04020084 0,12337145 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04020084 0,12321429 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04020084 0,12305753 ! neuron adhesion GO:0007158 12 7 0,000 0,04020084 0,12290117 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,04020084 0,1227452 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04020084 0,12258963 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04020084 0,12243445 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04020084 0,12227967 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04020084 0,12212528 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04020084 0,12197127 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04020084 0,12181766 ! mRNA stabilization GO:0048255 18 7 0,000 0,04020084 0,12166443 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04020084 0,12151158 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04020084 0,12135912 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04020084 0,12120704 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04020084 0,12105534 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04020084 0,12090402 ! lipoprotein transport GO:0042953 14 7 0,000 0,04020084 0,12075308 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04020084 0,12060252 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04020084 0,12045233 ! rhythmic behavior GO:0007622 15 7 0,000 0,04020084 0,12030251 ! estrogen metabolic process GO:0008210 17 7 0,000 0,04020084 0,12015307 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04020084 0,12000399 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04020084 0,11985529 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04020084 0,11970695 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04020084 0,11955899 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04020084 0,11941138 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04020084 0,11926414 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04020084 0,11911727 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04020084 0,11897075 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04020084 0,11882459 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04020084 0,1186788 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04020084 0,11853336 ! spinal cord patterning GO:0021511 13 7 0,000 0,04020084 0,11838827 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04020084 0,11824354 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04020084 0,11809917 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04020084 0,11795515 ! adrenal gland development GO:0030325 17 7 0,000 0,04020084 0,11781147 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04020084 0,11766815 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04020084 0,11752518 ! ovulation GO:0030728 9 7 0,000 0,04020084 0,11738255 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04020084 0,11724027 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04020084 0,11709833 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04020084 0,11695673 ! microtubule nucleation GO:0007020 20 7 0,000 0,04020084 0,11681548 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04020084 0,11667457 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04020084 0,116534 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04020084 0,11639377 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04020084 0,11625387 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04020084 0,11611431 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04020084 0,11597508 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04020084 0,11583619 ! galactose metabolic process GO:0006012 13 7 0,000 0,04020084 0,11569763 ! vesicle fusion GO:0006906 17 7 0,000 0,04020084 0,1155594 ! response to dietary excess GO:0002021 8 7 0,000 0,04020084 0,1154215 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04020084 0,11528393 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04020084 0,11514669 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04020084 0,11500977 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 0,000 0,04020084 0,11487318 ! purine salvage GO:0043101 10 7 0,000 0,04020084 0,11473692 ! nucleoside transport GO:0015858 8 7 0,000 0,04020084 0,11460097 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04020084 0,11446535 ! parturition GO:0007567 14 7 0,000 0,04020084 0,11433005 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04020084 0,11419506 ! rRNA modification GO:0000154 14 7 0,000 0,04020084 0,1140604 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04020084 0,11392605 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04020084 0,11379202 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04020084 0,11365831 ! macrophage differentiation GO:0030225 11 7 0,000 0,04020084 0,11352491 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04020084 0,11339182 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04020084 0,11325904 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04020084 0,11312657 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04020084 0,11299442 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04020084 0,11286257 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04020084 0,11273102 ! fibrinolysis GO:0042730 10 7 0,000 0,04020084 0,11259979 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04020084 0,11246886 ! eating behavior GO:0042755 7 7 0,000 0,04020084 0,11233823 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04020084 0,11220791 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04020084 0,11207789 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04020084 0,11194817 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04020084 0,11181875 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04020084 0,11168963 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04020084 0,11156081 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04020084 0,11143228 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04020084 0,11130405 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04020084 0,11117611 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04020084 0,11104847 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04020084 0,11092112 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04020084 0,11079407 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04020084 0,1106673 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04020084 0,11054082 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04020084 0,11041463 ! regulation of meiosis GO:0040020 12 7 0,000 0,04020084 0,11028873 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04020084 0,11016312 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04020084 0,11003779 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04020084 0,10991275 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04020084 0,10978799 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04020084 0,10966351 ! transcription termination GO:0006353 13 7 0,000 0,04020084 0,10953932 ! response to tumor cell GO:0002347 13 7 0,000 0,04020084 0,10941541 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04020084 0,10929177 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04020084 0,10916842 ! anaphase GO:0051322 17 7 0,000 0,04020084 0,10904534 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04020084 0,10892254 ! axonal fasciculation GO:0007413 18 7 0,000 0,04020084 0,10880002 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04020084 0,10867777 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04020084 0,1085558 ! diuresis GO:0030146 12 7 0,000 0,04020084 0,1084341 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04020084 0,10831268 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04020084 0,10819152 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04020084 0,10807064 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04020084 0,10795002 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04020084 0,10782968 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04020084 0,1077096 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04020084 0,10758979 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04020084 0,10747024 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04020084 0,10735096 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04020084 0,10723195 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04020084 0,1071132 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04020084 0,10699471 ! lymph node development GO:0048535 10 7 0,000 0,04020084 0,10687649 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04020084 0,10675852 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04020084 0,10664082 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04020084 0,10652337 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04020084 0,10640618 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04020084 0,10628925 ! adult feeding behavior GO:0008343 9 7 0,000 0,04020084 0,10617258 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04020084 0,10605616 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04020084 0,10594 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04020084 0,10582409 ! muscle adaptation GO:0043500 14 7 0,000 0,04020084 0,10570844 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04020084 0,10559303 ! retina homeostasis GO:0001895 12 7 0,000 0,04020084 0,10547788 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04020084 0,10536298 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04020084 0,10524833 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04020084 0,10513393 ! protein prenylation GO:0018342 18 7 0,000 0,04020084 0,10501978 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04020084 0,10490588 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04020084 0,10479222 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04020084 0,10467881 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,0412015 0,10716844 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,0412015 0,1070527 ! regulation of actin filament length GO:0030832 105 56 1,000 0,04256699 0,11048132 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,04394926 0,11394605 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04394926 0,11382339 ! maintenance of location GO:0051235 118 57 1,000 0,04394926 0,113701 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,04534808 0,11719385 ! regulation of endocytosis GO:0030100 91 58 1,000 0,04534808 0,11706811 ! adult behavior GO:0030534 99 58 1,000 0,04534808 0,11694263 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04534808 0,11681743 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04581109 0,11788394 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04581109 0,11775799 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,04581109 0,11763232 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04581109 0,11750691 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04581109 0,11738177 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04581109 0,1172569 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04581109 0,11713229 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04581109 0,11700794 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04581109 0,11688386 ! meiotic prophase I GO:0007128 13 8 0,000 0,04581109 0,11676005 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04581109 0,11663649 ! oligopeptide transport GO:0006857 15 8 0,000 0,04581109 0,1165132 ! UTP metabolic process GO:0046051 8 8 0,000 0,04581109 0,11639016 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04581109 0,11626739 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04581109 0,11614487 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04581109 0,11602261 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04581109 0,11590061 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04581109 0,11577887 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04581109 0,11565738 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04581109 0,11553615 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04581109 0,11541517 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04581109 0,11529444 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04581109 0,11517396 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04581109 0,11505374 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04581109 0,11493377 ! reflex GO:0060004 16 8 0,000 0,04581109 0,11481404 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04581109 0,11469457 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04581109 0,11457535 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04581109 0,11445637 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04581109 0,11433764 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04581109 0,11421915 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04581109 0,11410091 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04581109 0,11398292 ! histidine metabolic process GO:0006547 16 8 0,000 0,04581109 0,11386517 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04581109 0,11374766 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04581109 0,11363039 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04581109 0,11351337 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04581109 0,11339659 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,04581109 0,11328004 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04581109 0,11316374 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04581109 0,11304767 ! melanin metabolic process GO:0006582 15 8 0,000 0,04581109 0,11293185 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04581109 0,11281626 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04581109 0,1127009 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04581109 0,11258578 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04581109 0,1124709 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04581109 0,11235625 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04581109 0,11224184 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04581109 0,11212765 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04581109 0,1120137 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04581109 0,11189998 ! osteoblast development GO:0002076 16 8 0,000 0,04581109 0,11178649 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04581109 0,11167323 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04581109 0,11156021 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04581109 0,1114474 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04581109 0,11133483 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04581109 0,11122249 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04581109 0,11111037 ! response to UV-B GO:0010224 16 8 0,000 0,04581109 0,11099847 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04581109 0,1108868 ! intermediate filament organization GO:0045109 12 8 0,000 0,04581109 0,11077536 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04581109 0,11066414 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04581109 0,11055314 ! cellular extravasation GO:0045123 12 8 0,000 0,04581109 0,11044237 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04581109 0,11033181 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04581109 0,11022148 ! response to antibiotic GO:0046677 11 8 0,000 0,04581109 0,11011137 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04581109 0,11000148 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04581109 0,10989181 ! DNA topological change GO:0006265 12 8 0,000 0,04581109 0,10978235 ! response to tropane GO:0014073 15 8 0,000 0,04581109 0,10967312 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04581109 0,1095641 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,04581109 0,1094553 ! melanosome transport GO:0032402 13 8 0,000 0,04581109 0,10934671 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04581109 0,10923834 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04581109 0,10913018 ! mast cell activation GO:0045576 14 8 0,000 0,04581109 0,10902224 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04581109 0,10891451 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04581109 0,10880699 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04581109 0,10869969 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04581109 0,10859259 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04581109 0,10848571 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04581109 0,10837904 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04581109 0,10827258 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04581109 0,10816632 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04581109 0,10806028 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04581109 0,10795444 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04581109 0,10784881 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04581109 0,10774339 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04581109 0,10763817 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04581109 0,10753315 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04581109 0,10742835 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04581109 0,10732374 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04581109 0,10721934 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04581109 0,10711514 ! hormone catabolic process GO:0042447 17 8 0,000 0,04581109 0,10701115 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04581109 0,10690735 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04581109 0,10680376 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04581109 0,10670037 ! ATP catabolic process GO:0006200 11 8 0,000 0,04581109 0,10659718 ! blastocyst growth GO:0001832 19 8 0,000 0,04581109 0,10649419 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04581109 0,10639139 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04581109 0,1062888 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04581109 0,1061864 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04581109 0,1060842 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04581109 0,1059822 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04581109 0,10588039 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04581109 0,10577877 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04581109 0,10567736 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04581109 0,10557613 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04581109 0,1054751 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04581109 0,10537427 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04581109 0,10527362 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04581109 0,10517317 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04581109 0,10507291 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04581109 0,10497284 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04581109 0,10487296 ! regulation of cellular component size GO:0032535 109 59 1,000 0,04676319 0,1069508 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04676319 0,10684923 ! regulation of Rab protein signal transduction GO:0032483 92 59 1,000 0,04676319 0,10674786 GO:0032313|regulation of Rab GTPase activity, ! establishment of organelle localization GO:0051656 109 59 1,000 0,04676319 0,10664667 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,04819437 0,1098065 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,04819437 0,10970261 ! regulation of heart contraction GO:0008016 110 60 1,000 0,04819437 0,10959892 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,04819437 0,10949543 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,04964138 0,11267657 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,04964138 0,11257038 ! viral reproductive process GO:0022415 126 62 1,000 0,051104 0,11577798 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05138873 0,11631354 ! axon extension GO:0048675 15 9 0,000 0,05138873 0,11620422 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05138873 0,11609511 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05138873 0,1159862 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05138873 0,1158775 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05138873 0,115769 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05138873 0,1156607 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05138873 0,11555261 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05138873 0,11544472 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05138873 0,11533703 ! phosphate transport GO:0006817 19 9 0,000 0,05138873 0,11522954 ! reproductive behavior GO:0019098 19 9 0,000 0,05138873 0,11512225 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05138873 0,11501515 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05138873 0,11490826 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05138873 0,11480157 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05138873 0,11469508 ! GTP metabolic process GO:0046039 9 9 0,000 0,05138873 0,11458878 ! RNA methylation GO:0001510 15 9 0,000 0,05138873 0,11448268 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05138873 0,11437677 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05138873 0,11427106 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05138873 0,11416555 ! regulation of histone modification GO:0031056 12 9 0,000 0,05138873 0,11406023 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05138873 0,11395511 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05138873 0,11385018 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05138873 0,11374544 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05138873 0,11364089 ! chemosensory behavior GO:0007635 20 9 0,000 0,05138873 0,11353654 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05138873 0,11343238 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05138873 0,11332841 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05138873 0,11322463 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05138873 0,11312104 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05138873 0,11301763 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05138873 0,11291442 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05138873 0,1128114 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05138873 0,11270856 ! protein targeting to ER GO:0045047 22 9 0,000 0,05138873 0,11260591 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05138873 0,11250345 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05138873 0,11240117 ! T cell selection GO:0045058 23 9 0,000 0,05138873 0,11229908 ! endosome organization GO:0007032 17 9 0,000 0,05138873 0,11219718 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05138873 0,11209546 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05138873 0,11199392 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05138873 0,11189257 ! mannose metabolic process GO:0006013 13 9 0,000 0,05138873 0,1117914 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05138873 0,11169042 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05138873 0,11158961 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05138873 0,11148899 ! receptor clustering GO:0043113 18 9 0,000 0,05138873 0,11138855 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05138873 0,11128829 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05138873 0,11118821 ! ruffle organization GO:0031529 15 9 0,000 0,05138873 0,11108831 ! retinol metabolic process GO:0042572 18 9 0,000 0,05138873 0,11098859 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05138873 0,11088905 ! behavioral fear response GO:0001662 22 9 0,000 0,05138873 0,11078969 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05138873 0,1106905 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05138873 0,1105915 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05138873 0,11049266 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,05138873 0,11039401 ! protein heterooligomerization GO:0051291 16 9 0,000 0,05138873 0,11029553 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05138873 0,11019723 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05138873 0,1100991 ! segment specification GO:0007379 13 9 0,000 0,05138873 0,11000115 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05138873 0,10990337 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05138873 0,10980577 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05138873 0,10970833 ! response to amine stimulus GO:0014075 13 9 0,000 0,05138873 0,10961107 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05138873 0,10951399 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05138873 0,10941707 ! erythrocyte development GO:0048821 15 9 0,000 0,05138873 0,10932033 ! gas homeostasis GO:0033483 16 9 0,000 0,05138873 0,10922376 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05138873 0,10912735 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05138873 0,10903112 ! renal water homeostasis GO:0003091 14 9 0,000 0,05138873 0,10893506 ! postreplication repair GO:0006301 22 9 0,000 0,05138873 0,10883917 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05138873 0,10874344 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05138873 0,10864788 ! icosanoid secretion GO:0032309 15 9 0,000 0,05138873 0,10855249 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05138873 0,10845727 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05138873 0,10836222 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05138873 0,10826733 ! regulation of cell division GO:0051302 15 9 0,000 0,05138873 0,10817261 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05138873 0,10807805 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05138873 0,10798366 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05138873 0,10788943 ! sterol catabolic process GO:0016127 11 9 0,000 0,05138873 0,10779537 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05138873 0,10770147 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05138873 0,10760774 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05138873 0,10751417 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05138873 0,10742076 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05138873 0,10732751 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05138873 0,10723442 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05138873 0,1071415 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05138873 0,10704874 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05138873 0,10695613 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05138873 0,10686369 ! purine base metabolic process GO:0006144 21 9 0,000 0,05138873 0,10677141 ! pigment granule transport GO:0051904 17 9 0,000 0,05138873 0,10667929 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05138873 0,10658732 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05138873 0,10649551 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05138873 0,10640387 ! mitochondrion localization GO:0051646 15 9 0,000 0,05138873 0,10631237 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,05258198 0,10868749 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,05258198 0,1085942 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,05258198 0,10850106 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,05258198 0,10840809 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,0540751 0,11139101 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,05558315 0,11439953 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 1,000 0,05558315 0,11430176 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05693396 0,11697959 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,05693396 0,11687978 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05693396 0,11678014 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05693396 0,11668066 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,05693396 0,11658136 ! synapsis GO:0007129 13 10 0,000 0,05693396 0,11648223 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05693396 0,11638326 ! N-glycan processing GO:0006491 20 10 0,000 0,05693396 0,11628446 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05693396 0,11618583 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05693396 0,11608737 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05693396 0,11598908 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05693396 0,11589095 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05693396 0,11579298 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05693396 0,11569518 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05693396 0,11559755 ! androgen metabolic process GO:0008209 17 10 0,000 0,05693396 0,11550008 ! phospholipid efflux GO:0033700 16 10 0,000 0,05693396 0,11540278 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05693396 0,11530564 ! lung alveolus development GO:0048286 26 10 0,000 0,05693396 0,11520866 ! pathogenesis GO:0009405 13 10 0,000 0,05693396 0,11511185 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05693396 0,1150152 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05693396 0,11491871 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05693396 0,11482238 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05693396 0,11472621 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05693396 0,11463021 ! endoderm development GO:0007492 16 10 0,000 0,05693396 0,11453436 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05693396 0,11443868 ! arginine catabolic process GO:0006527 13 10 0,000 0,05693396 0,11434315 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05693396 0,11424779 ! proline metabolic process GO:0006560 13 10 0,000 0,05693396 0,11415258 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05693396 0,11405753 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05693396 0,11396264 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05693396 0,11386791 ! V(D)J recombination GO:0033151 28 10 0,000 0,05693396 0,11377334 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05693396 0,11367892 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05693396 0,11358466 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05693396 0,11349055 ! B cell proliferation GO:0042100 18 10 0,000 0,05693396 0,1133966 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05693396 0,11330281 ! multicellular organism growth GO:0035264 18 10 0,000 0,05693396 0,11320917 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05693396 0,11311569 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05693396 0,11302236 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05693396 0,11292918 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05693396 0,11283616 ! macroautophagy GO:0016236 17 10 0,000 0,05693396 0,11274329 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05693396 0,11265057 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05693396 0,11255801 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05693396 0,1124656 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05693396 0,11237334 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05693396 0,11228123 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05693396 0,11218927 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05693396 0,11209746 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05693396 0,1120058 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05693396 0,1119143 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05693396 0,11182294 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05693396 0,11173173 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05693396 0,11164067 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05693396 0,11154975 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05693396 0,11145899 ! response to dsRNA GO:0043331 20 10 0,000 0,05693396 0,11136837 ! DNA ligation GO:0006266 19 10 0,000 0,05693396 0,1112779 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05693396 0,11118758 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05693396 0,1110974 ! melanosome localization GO:0032400 16 10 0,000 0,05693396 0,11100737 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05693396 0,11091749 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05693396 0,11082775 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05693396 0,11073816 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05693396 0,11064871 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05693396 0,1105594 ! mRNA cleavage GO:0006379 17 10 0,000 0,05693396 0,11047024 ! protein sumoylation GO:0016925 15 10 0,000 0,05693396 0,11038122 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05693396 0,11029235 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05693396 0,11020362 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05693396 0,11011503 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05693396 0,11002659 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05693396 0,10993828 ! prophase GO:0051324 15 10 0,000 0,05693396 0,10985012 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05693396 0,1097621 ! apical protein localization GO:0045176 15 10 0,000 0,05693396 0,10967422 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05693396 0,10958648 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05693396 0,10949888 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05693396 0,10941142 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05693396 0,1093241 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05693396 0,10923692 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05693396 0,10914988 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05693396 0,10906298 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05693396 0,10897621 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05693396 0,10888959 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05693396 0,1088031 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05693396 0,10871675 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05693396 0,10863053 ! oocyte development GO:0048599 17 10 0,000 0,05693396 0,10854445 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05693396 0,10845851 ! blastocyst formation GO:0001825 17 10 0,000 0,05693396 0,1083727 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05693396 0,10828703 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05693396 0,1082015 ! activation of innate immune response GO:0002218 12 10 0,000 0,05693396 0,1081161 GO:0002758|innate immune response-activating signal transduction, ! establishment of cell polarity GO:0030010 16 10 0,000 0,05693396 0,10803084 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05693396 0,1079457 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05693396 0,10786071 ! localization within membrane GO:0051668 20 10 0,000 0,05693396 0,10777584 ! developmental maturation GO:0021700 116 66 1,000 0,05710589 0,10801633 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,0586431 0,11083684 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,0586431 0,11074984 ! activation of MAPK activity GO:0000187 115 67 1,000 0,0586431 0,11066298 ! lung development GO:0030324 144 67 1,000 0,0586431 0,11057626 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,0586431 0,11048966 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,0586431 0,11040321 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,0586431 0,11031689 ! amino acid transport GO:0006865 125 68 1,000 0,06019457 0,11314698 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,06019457 0,11305865 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,06019457 0,11297047 ! viral reproduction GO:0016032 134 68 1,000 0,06019457 0,11288241 ! regulation of lipase activity GO:0060191 130 68 1,000 0,06019457 0,1127945 ! urogenital system development GO:0001655 137 69 1,000 0,06176008 0,11563794 ! antigen processing and presentation GO:0019882 104 69 1,000 0,06176008 0,11554802 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06244695 0,11674231 ! respiratory burst GO:0045730 17 11 0,000 0,06244695 0,11665167 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06244695 0,11656118 ! neuron fate specification GO:0048665 17 11 0,000 0,06244695 0,11647082 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06244695 0,1163806 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06244695 0,11629052 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06244695 0,11620058 ! thyroid gland development GO:0030878 26 11 0,000 0,06244695 0,11611078 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,06244695 0,11602112 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06244695 0,1159316 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06244695 0,11584222 ! response to pain GO:0048265 24 11 0,000 0,06244695 0,11575297 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06244695 0,11566386 ! T cell proliferation GO:0042098 26 11 0,000 0,06244695 0,11557489 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06244695 0,11548605 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,06244695 0,11539735 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06244695 0,11530879 ! bone resorption GO:0045453 16 11 0,000 0,06244695 0,11522036 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,06244695 0,11513207 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06244695 0,11504392 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06244695 0,1149559 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06244695 0,11486801 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06244695 0,11478026 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06244695 0,11469264 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06244695 0,11460515 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06244695 0,1145178 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06244695 0,11443058 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06244695 0,1143435 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06244695 0,11425654 ! lipid digestion GO:0044241 18 11 0,000 0,06244695 0,11416972 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06244695 0,11408303 ! UV protection GO:0009650 19 11 0,000 0,06244695 0,11399648 ! adult heart development GO:0007512 14 11 0,000 0,06244695 0,11391005 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06244695 0,11382375 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06244695 0,11373759 ! temperature homeostasis GO:0001659 17 11 0,000 0,06244695 0,11365155 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06244695 0,11356565 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06244695 0,11347988 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06244695 0,11339423 ! regulation of organ growth GO:0046620 13 11 0,000 0,06244695 0,11330871 ! pigment granule localization GO:0051875 20 11 0,000 0,06244695 0,11322333 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06244695 0,11313807 ! vasoconstriction GO:0042310 18 11 0,000 0,06244695 0,11305294 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06244695 0,11296794 ! embryonic axis specification GO:0000578 18 11 0,000 0,06244695 0,11288306 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06244695 0,11279831 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06244695 0,1127137 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06244695 0,1126292 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06244695 0,11254484 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06244695 0,1124606 ! zymogen activation GO:0031638 15 11 0,000 0,06244695 0,11237648 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06244695 0,11229249 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06244695 0,11220863 ! nucleosome positioning GO:0016584 15 11 0,000 0,06244695 0,11212489 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06244695 0,11204128 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06244695 0,11195779 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06244695 0,11187443 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06244695 0,11179119 ! acid secretion GO:0046717 18 11 0,000 0,06244695 0,11170807 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06244695 0,11162508 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06244695 0,11154221 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06244695 0,11145946 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06244695 0,11137684 ! oocyte differentiation GO:0009994 18 11 0,000 0,06244695 0,11129434 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06244695 0,11121196 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06244695 0,1111297 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06244695 0,11104756 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06244695 0,11096555 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06244695 0,11088366 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06244695 0,11080188 ! embryonic gut development GO:0048566 15 11 0,000 0,06244695 0,11072023 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06244695 0,1106387 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06244695 0,11055729 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06244695 0,110476 ! defense response to fungus GO:0050832 13 11 0,000 0,06244695 0,11039482 ! developmental induction GO:0031128 19 11 0,000 0,06244695 0,11031377 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06244695 0,11023284 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06244695 0,11015202 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06244695 0,11007132 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06244695 0,10999074 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06244695 0,10991028 ! nucleus localization GO:0051647 19 11 0,000 0,06244695 0,10982994 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06244695 0,10974971 ! appendage morphogenesis GO:0035107 135 70 1,000 0,06333941 0,11123695 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,06333941 0,11115581 ! amine catabolic process GO:0009310 117 71 1,000 0,06493235 0,11386825 ! reproductive structure development GO:0048608 113 71 1,000 0,06493235 0,11378531 ! appendage development GO:0048736 136 71 1,000 0,06493235 0,1137025 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,06493235 0,11361981 ! regulation of immune effector process GO:0002697 137 71 1,000 0,06493235 0,11353723 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,06653869 0,1162615 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,06653869 0,11617713 ! respiratory system development GO:0060541 153 72 1,000 0,06653869 0,11609289 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06792789 0,1184308 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06792789 0,11834505 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06792789 0,11825941 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,06792789 0,1181739 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06792789 0,11808852 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,06792789 0,11800326 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06792789 0,11791812 ! cartilage condensation GO:0001502 20 12 0,000 0,06792789 0,1178331 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,06792789 0,11774821 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06792789 0,11766343 ! protein complex disassembly GO:0043241 27 12 0,000 0,06792789 0,11757878 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06792789 0,11749426 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06792789 0,11740985 ! hippocampus development GO:0021766 26 12 0,000 0,06792789 0,11732556 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06792789 0,1172414 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06792789 0,11715735 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06792789 0,11707343 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06792789 0,11698963 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06792789 0,11690594 ! drug transport GO:0015893 16 12 0,000 0,06792789 0,11682238 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06792789 0,11673894 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06792789 0,11665561 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06792789 0,1165724 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06792789 0,11648932 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06792789 0,11640635 ! forebrain cell migration GO:0021885 21 12 0,000 0,06792789 0,11632349 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06792789 0,11624076 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06792789 0,11615814 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06792789 0,11607565 ! entry into host cell GO:0030260 32 12 0,000 0,06792789 0,11599326 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06792789 0,115911 ! monoamine transport GO:0015844 18 12 0,000 0,06792789 0,11582885 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06792789 0,11574682 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06792789 0,1156649 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06792789 0,1155831 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06792789 0,11550142 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06792789 0,11541985 ! protein homotetramerization GO:0051289 21 12 0,000 0,06792789 0,1153384 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06792789 0,11525706 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06792789 0,11517583 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06792789 0,11509473 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06792789 0,11501373 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06792789 0,11493285 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06792789 0,11485208 ! cranial nerve development GO:0021545 20 12 0,000 0,06792789 0,11477143 ! fucose catabolic process GO:0019317 22 12 0,000 0,06792789 0,11469088 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06792789 0,11461046 ! histone acetylation GO:0016573 26 12 0,000 0,06792789 0,11453014 ! histone methylation GO:0016571 26 12 0,000 0,06792789 0,11444994 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06792789 0,11436985 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06792789 0,11428987 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06792789 0,11421 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06792789 0,11413024 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06792789 0,1140506 ! spleen development GO:0048536 22 12 0,000 0,06792789 0,11397107 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06792789 0,11389164 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06792789 0,11381233 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06792789 0,11373313 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06792789 0,11365404 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,06792789 0,11357506 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06792789 0,11349619 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06792789 0,11341743 ! response to cold GO:0009409 17 12 0,000 0,06792789 0,11333877 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06792789 0,11326023 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06792789 0,11318179 ! regulation of blood pressure GO:0008217 125 73 1,000 0,06815822 0,11348698 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,06979074 0,11612484 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,06979074 0,11604459 ! eye development GO:0001654 143 74 1,000 0,06979074 0,11596444 ! organelle localization GO:0051640 136 74 1,000 0,06979074 0,11588441 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,07143603 0,11853455 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,07143603 0,11845285 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,07143603 0,11837128 ! defense response to bacterium GO:0042742 89 76 1,000 0,0730939 0,12103505 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07337698 0,12142023 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07337698 0,12133677 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07337698 0,12125344 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07337698 0,12117022 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07337698 0,12108711 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07337698 0,12100412 ! lipid localization GO:0010876 28 13 0,000 0,07337698 0,12092124 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07337698 0,12083847 ! organelle fusion GO:0048284 32 13 0,000 0,07337698 0,12075582 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07337698 0,12067328 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07337698 0,12059085 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07337698 0,12050854 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07337698 0,12042634 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07337698 0,12034424 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07337698 0,12026227 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07337698 0,1201804 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07337698 0,12009864 ! methionine metabolic process GO:0006555 27 13 0,000 0,07337698 0,120017 ! plasma membrane organization GO:0007009 24 13 0,000 0,07337698 0,11993547 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07337698 0,11985404 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07337698 0,11977273 ! Golgi organization GO:0007030 24 13 0,000 0,07337698 0,11969153 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07337698 0,11961044 ! response to X-ray GO:0010165 25 13 0,000 0,07337698 0,11952946 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07337698 0,11944858 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07337698 0,11936782 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07337698 0,11928717 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07337698 0,11920662 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07337698 0,11912619 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07337698 0,11904586 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07337698 0,11896564 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07337698 0,11888553 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07337698 0,11880552 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07337698 0,11872563 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07337698 0,11864584 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07337698 0,11856616 ! ribosome assembly GO:0042255 17 13 0,000 0,07337698 0,11848658 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,07337698 0,11840711 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07337698 0,11832775 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07337698 0,1182485 ! chromatin silencing GO:0006342 26 13 0,000 0,07337698 0,11816935 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07337698 0,11809031 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07337698 0,11801137 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07337698 0,11793254 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07337698 0,11785381 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07337698 0,11777519 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07337698 0,11769667 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07337698 0,11761826 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07337698 0,11753995 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07337698 0,11746175 ! embryonic placenta development GO:0001892 23 13 0,000 0,07337698 0,11738365 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07337698 0,11730565 ! insulin secretion GO:0030073 23 13 0,000 0,07337698 0,11722776 ! actin filament polymerization GO:0030041 24 13 0,000 0,07337698 0,11714997 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07337698 0,11707229 ! acrosome reaction GO:0007340 18 13 0,000 0,07337698 0,1169947 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,07476415 0,11912751 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,07476415 0,11904867 ! protein oligomerization GO:0051259 139 78 1,000 0,07644656 0,12164711 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,07814096 0,12426117 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,07814096 0,1241791 ! rRNA transcription GO:0009303 25 14 0,000 0,07879439 0,12513485 ! lactation GO:0007595 26 14 0,000 0,07879439 0,1250523 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,07879439 0,12496987 ! reproductive cellular process GO:0048610 20 14 0,000 0,07879439 0,12488754 ! tRNA modification GO:0006400 20 14 0,000 0,07879439 0,12480533 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07879439 0,12472322 ! regulation of S phase GO:0033261 23 14 0,000 0,07879439 0,12464122 ! water transport GO:0006833 21 14 0,000 0,07879439 0,12455932 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07879439 0,12447754 ! non-recombinational repair GO:0000726 25 14 0,000 0,07879439 0,12439586 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07879439 0,12431429 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07879439 0,12423282 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07879439 0,12415147 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07879439 0,12407022 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07879439 0,12398907 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07879439 0,12390803 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07879439 0,1238271 ! arginine metabolic process GO:0006525 17 14 0,000 0,07879439 0,12374627 ! regulation of heart rate GO:0002027 24 14 0,000 0,07879439 0,12366555 ! organic alcohol transport GO:0015850 29 14 0,000 0,07879439 0,12358494 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07879439 0,12350442 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07879439 0,12342402 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07879439 0,12334372 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07879439 0,12326352 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07879439 0,12318342 ! L-amino acid transport GO:0015807 30 14 0,000 0,07879439 0,12310344 ! bone mineralization GO:0030282 17 14 0,000 0,07879439 0,12302355 ! stem cell development GO:0048864 43 14 0,000 0,07879439 0,12294377 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07879439 0,12286409 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07879439 0,12278451 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07879439 0,12270504 ! cerebellum development GO:0021549 21 14 0,000 0,07879439 0,12262567 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07879439 0,12254641 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07879439 0,12246724 ! response to gamma radiation GO:0010332 28 14 0,000 0,07879439 0,12238818 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07879439 0,12230922 ! cofactor transport GO:0051181 26 14 0,000 0,07879439 0,12223036 ! NADP metabolic process GO:0006739 24 14 0,000 0,07879439 0,1221516 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07879439 0,12207295 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07879439 0,1219944 ! intestinal absorption GO:0050892 25 14 0,000 0,07879439 0,12191594 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07879439 0,12183759 ! oxygen transport GO:0015671 21 14 0,000 0,07879439 0,12175934 ! male genitalia development GO:0030539 24 14 0,000 0,07879439 0,12168119 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07879439 0,12160314 ! regulation of axon extension GO:0030516 37 14 0,000 0,07879439 0,12152519 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,07879439 0,12144734 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07879439 0,12136958 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,08156491 0,12555673 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,08156491 0,12547645 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0841803 0,12941713 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0841803 0,12933448 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,0841803 0,12925195 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0841803 0,12916952 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0841803 0,12908719 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0841803 0,12900497 ! copper ion transport GO:0006825 20 15 0,000 0,0841803 0,12892285 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0841803 0,12884084 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0841803 0,12875893 ! sulfate transport GO:0008272 23 15 0,000 0,0841803 0,12867713 ! response to cAMP GO:0051591 22 15 0,000 0,0841803 0,12859543 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0841803 0,12851383 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0841803 0,12843234 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0841803 0,12835095 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0841803 0,12826967 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0841803 0,12818848 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0841803 0,1281074 ! pituitary gland development GO:0021983 29 15 0,000 0,0841803 0,12802642 ! vesicle coating GO:0006901 33 15 0,000 0,0841803 0,12794555 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0841803 0,12786477 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0841803 0,1277841 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0841803 0,12770353 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0841803 0,12762306 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0841803 0,1275427 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0841803 0,12746243 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0841803 0,12738227 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0841803 0,1273022 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0841803 0,12722224 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0841803 0,12714237 ! histone deacetylation GO:0016575 20 15 0,000 0,0841803 0,12706261 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0841803 0,12698295 ! tissue regeneration GO:0042246 26 15 0,000 0,0841803 0,12690338 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0841803 0,12682392 ! water homeostasis GO:0030104 27 15 0,000 0,0841803 0,12674456 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0841803 0,12666529 ! muscle maintenance GO:0046716 26 15 0,000 0,0841803 0,12658613 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0841803 0,12650706 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0841803 0,12642809 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0841803 0,12634922 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0841803 0,12627045 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0841803 0,12619178 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0841803 0,1261132 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0841803 0,12603472 ! peptide hormone processing GO:0016486 23 15 0,000 0,0841803 0,12595634 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,08678583 0,12977421 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,08854805 0,13232709 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,08854805 0,13224495 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0895349 0,13363584 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,0895349 0,13355299 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,0895349 0,13347025 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0895349 0,1333876 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0895349 0,13330506 ! bone remodeling GO:0046849 27 16 0,000 0,0895349 0,13322262 ! filopodium assembly GO:0046847 32 16 0,000 0,0895349 0,13314028 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0895349 0,13305805 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0895349 0,13297591 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0895349 0,13289388 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0895349 0,13281195 ! startle response GO:0001964 28 16 0,000 0,0895349 0,13273012 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0895349 0,13264838 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0895349 0,13256676 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0895349 0,13248523 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0895349 0,1324038 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0895349 0,13232247 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0895349 0,13224124 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0895349 0,13216011 ! response to osmotic stress GO:0006970 25 16 0,000 0,0895349 0,13207908 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0895349 0,13199815 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,0895349 0,13191732 ! fructose metabolic process GO:0006000 25 16 0,000 0,0895349 0,13183658 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0895349 0,13175595 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,0895349 0,13167541 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0895349 0,13159498 ! axon cargo transport GO:0008088 43 16 0,000 0,0895349 0,13151464 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0895349 0,1314344 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0895349 0,13135425 ! DNA replication initiation GO:0006270 27 16 0,000 0,0895349 0,13127421 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0895349 0,13119426 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0895349 0,13111441 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0895349 0,13103466 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0895349 0,130955 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,0895349 0,13087544 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0895349 0,13079598 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0895349 0,13071661 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0895349 0,13063734 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0895349 0,13055817 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0895349 0,13047909 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0895349 0,13040011 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,0895349 0,13032122 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! amine biosynthetic process GO:0009309 138 86 1,000 0,09032092 0,13138581 ! alcohol catabolic process GO:0046164 130 86 1,000 0,09032092 0,13130642 ! amine transport GO:0015837 155 86 1,000 0,09032092 0,13122713 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,09210425 0,13373737 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,09389787 0,13625951 ! regulation of neurological system process GO:0031644 148 88 1,000 0,09389787 0,13617738 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09485838 0,1374875 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09485838 0,13740473 ! metencephalon development GO:0022037 30 17 0,000 0,09485838 0,13732205 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09485838 0,13723948 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09485838 0,137157 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09485838 0,13707463 ! signal complex assembly GO:0007172 41 17 0,000 0,09485838 0,13699235 ! endothelial cell migration GO:0043542 28 17 0,000 0,09485838 0,13691017 ! inositol metabolic process GO:0006020 28 17 0,000 0,09485838 0,13682809 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09485838 0,13674611 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09485838 0,13666422 ! glial cell development GO:0021782 27 17 0,000 0,09485838 0,13658244 ! limbic system development GO:0021761 36 17 0,000 0,09485838 0,13650075 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09485838 0,13641916 ! adult walking behavior GO:0007628 33 17 0,000 0,09485838 0,13633767 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09485838 0,13625627 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09485838 0,13617497 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09485838 0,13609377 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09485838 0,13601267 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,09485838 0,13593166 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,09485838 0,13585075 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09485838 0,13576993 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09485838 0,13568921 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,09485838 0,13560859 ! NAD metabolic process GO:0019674 29 17 0,000 0,09485838 0,13552806 ! membrane budding GO:0006900 37 17 0,000 0,09485838 0,13544763 ! DNA integration GO:0015074 29 17 0,000 0,09485838 0,13536729 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,09485838 0,13528705 ! regulation of protein binding GO:0043393 33 17 0,000 0,09485838 0,1352069 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09485838 0,13512685 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09485838 0,1350469 ! genitalia development GO:0048806 30 17 0,000 0,09485838 0,13496703 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,09485838 0,13488727 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09485838 0,13480759 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09485838 0,13472801 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09485838 0,13464853 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09485838 0,13456913 ! steroid catabolic process GO:0006706 31 17 0,000 0,09485838 0,13448984 ! gas transport GO:0015669 25 17 0,000 0,09485838 0,13441063 ! organic cation transport GO:0015695 31 17 0,000 0,09485838 0,13433152 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09485838 0,1342525 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,09485838 0,13417358 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09485838 0,13409474 ! microspike assembly GO:0030035 36 17 0,000 0,09485838 0,134016 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09485838 0,13393735 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09485838 0,1338588 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,09570159 0,13496953 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,1001509 0,14116172 ! neuron maturation GO:0042551 42 18 0,000 0,1001509 0,14107908 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,1001509 0,14099653 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,1001509 0,14091407 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,1001509 0,14083171 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,1001509 0,14074945 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,1001509 0,14066729 ! memory GO:0007613 31 18 0,000 0,1001509 0,14058522 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,1001509 0,14050324 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,1001509 0,14042136 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,1001509 0,14033958 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,1001509 0,14025789 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,1001509 0,1401763 ! glutamine metabolic process GO:0006541 29 18 0,000 0,1001509 0,1400948 ! response to retinoic acid GO:0032526 26 18 0,000 0,1001509 0,1400134 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,1001509 0,13993209 ! response to fungus GO:0009620 21 18 0,000 0,1001509 0,13985088 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,1001509 0,13976976 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,1001509 0,13968873 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,1001509 0,1396078 ! vitamin transport GO:0051180 27 18 0,000 0,1001509 0,13952696 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,1001509 0,13944622 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,1001509 0,13936556 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,1001509 0,13928501 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,1001509 0,13920454 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,1001509 0,13912417 ! nerve development GO:0021675 28 18 0,000 0,1001509 0,13904389 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,1001509 0,1389637 ! regulation of defense response GO:0031347 149 92 1,000 0,1011716 0,14029906 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,10301397 0,14277167 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,10301397 0,14268948 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,10486558 0,14517065 ! regulation of T cell activation GO:0050863 158 94 1,000 0,10486558 0,14508717 ! protein secretion GO:0009306 39 19 0,000 0,10541265 0,14576025 ! positive regulation of translation GO:0045727 30 19 0,000 0,10541265 0,14567653 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10541265 0,1455929 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10541265 0,14550937 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10541265 0,14542594 ! lipid phosphorylation GO:0046834 35 19 0,000 0,10541265 0,1453426 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10541265 0,14525936 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10541265 0,14517621 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10541265 0,14509315 ! cerebral cortex development GO:0021987 36 19 0,000 0,10541265 0,1450102 ! pigmentation during development GO:0048066 41 19 0,000 0,10541265 0,14492733 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10541265 0,14484457 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10541265 0,14476189 ! heme metabolic process GO:0042168 36 19 0,000 0,10541265 0,14467931 ! neuromuscular junction development GO:0007528 34 19 0,000 0,10541265 0,14459683 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10541265 0,14451444 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10541265 0,14443214 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10541265 0,14434993 ! peptide cross-linking GO:0018149 37 19 0,000 0,10541265 0,14426782 ! heart process GO:0003015 30 19 0,000 0,10541265 0,14418581 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10541265 0,14410388 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,10541265 0,14402205 ! G1 phase GO:0051318 40 19 0,000 0,10541265 0,14394031 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10541265 0,14385867 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10541265 0,14377712 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10541265 0,14369566 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10541265 0,14361429 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10541265 0,14353301 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10541265 0,14345183 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10541265 0,14337074 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10541265 0,14328974 ! cilium assembly GO:0042384 37 19 0,000 0,10541265 0,14320883 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10541265 0,14312801 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,10672625 0,14482987 ! leukocyte differentiation GO:0002521 202 96 1,000 0,10859582 0,14728385 ! positive regulation of immune response GO:0050778 156 96 1,000 0,10859582 0,14720087 ! protein ubiquitination GO:0016567 217 97 1,000 0,11047412 0,14966257 ! hormone metabolic process GO:0042445 157 97 1,000 0,11047412 0,14957835 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,11064381 0,14972385 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11064381 0,14963968 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11064381 0,14955562 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,11064381 0,14947164 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11064381 0,14938777 ! response to vitamin GO:0033273 31 20 0,000 0,11064381 0,14930398 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11064381 0,14922029 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,11064381 0,14913669 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11064381 0,14905319 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11064381 0,14896978 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11064381 0,14888646 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,11064381 0,14880324 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11064381 0,14872011 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11064381 0,14863707 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11064381 0,14855413 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,11064381 0,14847128 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11064381 0,14838852 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11064381 0,14830585 ! body fluid secretion GO:0007589 31 20 0,000 0,11064381 0,14822327 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11064381 0,14814079 ! peptide secretion GO:0002790 35 20 0,000 0,11064381 0,1480584 ! stem cell differentiation GO:0048863 53 20 0,000 0,11064381 0,1479761 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11064381 0,14789389 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11064381 0,14781177 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11064381 0,14772974 ! sensory perception of pain GO:0019233 30 20 0,000 0,11064381 0,14764781 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11064381 0,14756596 ! diencephalon development GO:0021536 34 20 0,000 0,11064381 0,14748421 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11064381 0,14740255 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11064381 0,14732097 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11064381 0,14723949 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,11064381 0,1471581 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11064381 0,1470768 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11064381 0,14699558 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11064381 0,14691446 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11064381 0,14683342 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11064381 0,14675248 ! regulation of glucose import GO:0046324 29 20 0,000 0,11064381 0,14667162 GO:0010827|regulation of glucose transport, ! actin filament-based movement GO:0030048 43 20 0,000 0,11064381 0,14659086 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11064381 0,14651018 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,11064381 0,14642959 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11064381 0,14634909 ! negative regulation of translation GO:0017148 29 20 0,000 0,11064381 0,14626868 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11064381 0,14618836 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11064381 0,14610812 ! interphase GO:0051325 213 98 1,000 0,11236098 0,1482943 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,11236098 0,148213 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 1,000 0,11425624 0,15063042 ! regulation of cell killing GO:0031341 42 21 0,000 0,11584455 0,15264073 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11584455 0,15255719 ! hormone secretion GO:0046879 38 21 0,000 0,11584455 0,15247373 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11584455 0,15239037 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11584455 0,15230709 ! axis specification GO:0009798 38 21 0,000 0,11584455 0,15222391 ! ovarian follicle development GO:0001541 35 21 0,000 0,11584455 0,15214082 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11584455 0,15205782 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11584455 0,15197491 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,11584455 0,15189209 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11584455 0,15180936 ! cell aging GO:0007569 44 21 0,000 0,11584455 0,15172672 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11584455 0,15164417 ! cytolysis GO:0019835 24 21 0,000 0,11584455 0,15156171 ! vasodilation GO:0042311 39 21 0,000 0,11584455 0,15147934 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11584455 0,15139706 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11584455 0,15131486 ! oogenesis GO:0048477 36 21 0,000 0,11584455 0,15123276 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,11584455 0,15115075 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11584455 0,15106882 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,11584455 0,15098699 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11584455 0,15090524 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11584455 0,15082358 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11584455 0,15074201 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11584455 0,15066053 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11584455 0,15057914 ! collagen catabolic process GO:0030574 28 21 0,000 0,11584455 0,15049783 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11584455 0,15041661 ! gut development GO:0048565 39 21 0,000 0,11584455 0,15033548 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,12101505 0,15696076 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12101505 0,15687619 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12101505 0,15679171 ! microtubule-based transport GO:0010970 54 22 0,000 0,12101505 0,15670732 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,12101505 0,15662302 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12101505 0,15653882 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12101505 0,1564547 ! keratinization GO:0031424 28 22 0,000 0,12101505 0,15637068 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12101505 0,15628674 ! sensory perception of taste GO:0050909 28 22 0,000 0,12101505 0,1562029 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,12101505 0,15611914 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12101505 0,15603548 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12101505 0,1559519 ! vacuolar transport GO:0007034 36 22 0,000 0,12101505 0,15586842 ! lysosome organization GO:0007040 41 22 0,000 0,12101505 0,15578502 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12101505 0,15570171 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12101505 0,15561849 ! fucose metabolic process GO:0006004 39 22 0,000 0,12101505 0,15553537 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12101505 0,15545232 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,12101505 0,15536937 ! ureteric bud development GO:0001657 43 22 0,000 0,12101505 0,15528651 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12101505 0,15520373 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12101505 0,15512105 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12101505 0,15503845 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12101505 0,15495594 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12101505 0,15487351 ! sarcomere organization GO:0045214 30 22 0,000 0,12101505 0,15479118 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,12101505 0,15470893 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12101505 0,15462677 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12101505 0,15454469 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12101505 0,15446271 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,12101505 0,15438081 ! protein stabilization GO:0050821 39 22 0,000 0,12101505 0,15429899 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,12615548 0,16076805 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12615548 0,16068295 ! viral genome replication GO:0019079 41 23 0,000 0,12615548 0,16059793 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12615548 0,160513 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12615548 0,16042816 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12615548 0,16034342 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12615548 0,16025876 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12615548 0,16017419 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12615548 0,16008971 ! visual behavior GO:0007632 42 23 0,000 0,12615548 0,16000532 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,12615548 0,15992102 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12615548 0,1598368 ! response to ethanol GO:0045471 46 23 0,000 0,12615548 0,15975268 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12615548 0,15966864 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,12615548 0,15958469 ! peroxisome organization GO:0007031 37 23 0,000 0,12615548 0,15950083 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12615548 0,15941706 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12615548 0,15933338 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12615548 0,15924978 ! sex determination GO:0007530 47 23 0,000 0,12615548 0,15916628 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,12615548 0,15908285 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12615548 0,15899952 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12615548 0,15891628 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12615548 0,15883312 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12615548 0,15875005 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12615548 0,15866706 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12615548 0,15858416 ! fatty acid transport GO:0015908 44 23 0,000 0,12615548 0,15850135 ! platelet activation GO:0030168 37 23 0,000 0,12615548 0,15841863 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12615548 0,15833599 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12615548 0,15825343 ! hormone transport GO:0009914 40 23 0,000 0,12615548 0,15817097 ! cell-cell recognition GO:0009988 25 23 0,000 0,12615548 0,15808859 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12615548 0,15800629 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,12615548 0,15792408 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12615548 0,15784196 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12615548 0,15775992 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,13126602 0,16406548 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13126602 0,1639803 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,13126602 0,1638952 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,13126602 0,16381019 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13126602 0,16372527 ! vesicle docking GO:0048278 47 24 0,000 0,13126602 0,16364044 ! spinal cord development GO:0021510 47 24 0,000 0,13126602 0,1635557 ! vacuole organization GO:0007033 43 24 0,000 0,13126602 0,16347104 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13126602 0,16338647 ! digestive system process GO:0022600 39 24 0,000 0,13126602 0,16330199 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13126602 0,1632176 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13126602 0,16313329 ! regulation of behavior GO:0050795 43 24 0,000 0,13126602 0,16304907 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13126602 0,16296494 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13126602 0,16288089 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13126602 0,16279693 ! membrane depolarization GO:0051899 39 24 0,000 0,13126602 0,16271306 ! pallium development GO:0021543 49 24 0,000 0,13126602 0,16262927 ! pentose metabolic process GO:0019321 35 24 0,000 0,13126602 0,16254557 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,13126602 0,16246196 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13126602 0,16237843 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13126602 0,16229499 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13126602 0,16221163 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13126602 0,16212836 GO:0033013|tetrapyrrole metabolic process, ! protein tetramerization GO:0051262 52 24 0,000 0,13126602 0,16204518 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,13634684 0,16823103 ! myelination GO:0042552 45 25 0,000 0,13634684 0,1681448 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13634684 0,16805866 ! phototransduction GO:0007602 33 25 0,000 0,13634684 0,16797261 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13634684 0,16788665 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,13634684 0,16780077 ! sperm motility GO:0030317 31 25 0,000 0,13634684 0,16771498 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13634684 0,16762928 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,13634684 0,16754367 ! receptor metabolic process GO:0043112 46 25 0,000 0,13634684 0,16745815 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13634684 0,16737271 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,13634684 0,16728736 ! neural crest cell development GO:0014032 54 25 0,000 0,13634684 0,16720209 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13634684 0,16711692 ! negative regulation of cell development GO:0010721 73 25 0,000 0,13634684 0,16703183 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13634684 0,16694682 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13634684 0,16686191 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,13634684 0,16677708 ! somitogenesis GO:0001756 43 25 0,000 0,13634684 0,16669233 ! immunoglobulin production GO:0002377 55 25 0,000 0,13634684 0,16660767 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13634684 0,1665231 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13634684 0,16643861 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13634684 0,16635421 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13634684 0,1662699 ! telomere organization GO:0032200 43 25 0,000 0,13634684 0,16618567 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,13634684 0,16610152 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,13634684 0,16601746 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14139812 0,17208087 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14139812 0,17199387 ! initiation of viral infection GO:0019059 57 26 0,000 0,14139812 0,17190696 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14139812 0,17182014 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14139812 0,1717334 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14139812 0,17164676 ! tube lumen formation GO:0035148 50 26 0,000 0,14139812 0,1715602 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14139812 0,17147373 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14139812 0,17138734 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14139812 0,17130104 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,14139812 0,17121483 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14139812 0,17112871 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14139812 0,17104267 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14139812 0,17095672 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14139812 0,17087086 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14139812 0,17078508 ! blastocyst development GO:0001824 49 26 0,000 0,14139812 0,17069938 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14139812 0,17061378 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14139812 0,17052826 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14139812 0,17044282 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,14642002 0,17640789 ! neuron fate commitment GO:0048663 48 27 0,000 0,14642002 0,1763196 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,14642002 0,1762314 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14642002 0,17614328 ! iron ion transport GO:0006826 59 27 0,000 0,14642002 0,17605525 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14642002 0,17596731 ! protein amino acid acylation GO:0043543 55 27 0,000 0,14642002 0,17587946 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14642002 0,1757917 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14642002 0,17570402 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14642002 0,17561643 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14642002 0,17552893 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14642002 0,17544151 ! autophagy GO:0006914 41 27 0,000 0,14642002 0,17535419 ! male gonad development GO:0008584 44 27 0,000 0,14642002 0,17526695 ! response to toxin GO:0009636 47 27 0,000 0,14642002 0,17517979 ! primary neural tube formation GO:0014020 51 27 0,000 0,14642002 0,17509272 ! base-excision repair GO:0006284 41 27 0,000 0,14642002 0,17500574 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14642002 0,17491885 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14642002 0,17483204 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14642002 0,17474532 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14642002 0,17465868 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,14642002 0,17457213 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,14642002 0,17448567 ! circadian rhythm GO:0007623 50 28 0,000 0,15141271 0,18034603 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15141271 0,18025679 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,15141271 0,18016764 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15141271 0,18007858 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,15141271 0,17998961 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15141271 0,17990073 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15141271 0,17981193 ! synaptogenesis GO:0007416 42 28 0,000 0,15141271 0,17972322 ! lipid oxidation GO:0034440 43 28 0,000 0,15141271 0,1796346 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15141271 0,17954607 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15141271 0,17945762 ! translational initiation GO:0006413 65 29 0,000 0,15637636 0,1852494 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15637636 0,18515823 ! regulation of pH GO:0006885 43 29 0,000 0,15637636 0,18506715 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,15637636 0,18497617 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15637636 0,18488527 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15637636 0,18479446 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15637636 0,18470374 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15637636 0,18461311 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15637636 0,18452257 ! cell fate determination GO:0001709 60 29 0,000 0,15637636 0,18443212 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15637636 0,18434176 ! detection of light stimulus GO:0009583 38 29 0,000 0,15637636 0,18425148 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15637636 0,18416129 ! tissue homeostasis GO:0001894 48 29 0,000 0,15637636 0,1840712 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,15637636 0,18398119 ! zinc ion transport GO:0006829 45 30 0,000 0,16131114 0,18969434 ! membrane docking GO:0022406 61 30 0,000 0,16131114 0,18960167 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16131114 0,18950909 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16131114 0,1894166 ! acute-phase response GO:0006953 49 30 0,000 0,16131114 0,1893242 ! myofibril assembly GO:0030239 47 30 0,000 0,16131114 0,18923189 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16131114 0,18913968 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16131114 0,18904755 ! phospholipid transport GO:0015914 51 30 0,000 0,16131114 0,18895551 ! ensheathment of neurons GO:0007272 57 30 0,000 0,16131114 0,18886356 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16131114 0,1887717 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16131114 0,18867993 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,16131114 0,18858825 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,16131114 0,18849666 ! eye morphogenesis GO:0048592 60 30 0,000 0,16131114 0,18840515 ! regulation of B cell activation GO:0050864 50 30 0,000 0,16131114 0,18831374 ! response to heat GO:0009408 50 30 0,000 0,16131114 0,18822241 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16621723 0,19385295 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16621723 0,19375903 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16621723 0,1936652 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16621723 0,19357146 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16621723 0,19347781 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16621723 0,19338426 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16621723 0,19329079 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16621723 0,19319741 ! ovulation cycle process GO:0022602 49 31 0,000 0,16621723 0,19310413 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16621723 0,19301093 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16621723 0,19291782 ! peptide transport GO:0015833 55 31 0,000 0,16621723 0,1928248 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16621723 0,19273188 ! iron ion homeostasis GO:0055072 54 31 0,000 0,16621723 0,19263904 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16621723 0,19254629 ! mesoderm formation GO:0001707 69 31 0,000 0,16621723 0,19245363 ! natural killer cell activation GO:0030101 45 31 0,000 0,16621723 0,19236106 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16621723 0,19226858 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,16621723 0,19217619 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16621723 0,19208388 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,17109477 0,19762555 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,17109477 0,19753072 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17109477 0,19743598 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,17109477 0,19734133 ! cholesterol transport GO:0030301 56 32 0,000 0,17109477 0,19724677 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,17109477 0,1971523 ! spliceosome assembly GO:0000245 67 32 0,000 0,17109477 0,19705793 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17109477 0,19696364 ! metanephros development GO:0001656 74 32 0,000 0,17109477 0,19686945 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17109477 0,19677534 ! response to ionizing radiation GO:0010212 65 32 0,000 0,17109477 0,19668132 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,17109477 0,1965874 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17109477 0,19649356 ! muscle cell development GO:0055001 49 32 0,000 0,17109477 0,19639982 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17109477 0,19630616 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17109477 0,19621259 ! ovulation cycle GO:0042698 51 32 0,000 0,17109477 0,19611911 ! peripheral nervous system development GO:0007422 64 32 0,000 0,17109477 0,19602572 ! BMP signaling pathway GO:0030509 64 32 0,000 0,17109477 0,19593242 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17109477 0,19583921 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,17109477 0,19574608 ! gene silencing GO:0016458 65 32 0,000 0,17109477 0,19565305 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,17594394 0,20110267 ! post-embryonic development GO:0009791 69 33 0,000 0,17594394 0,20100718 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,17594394 0,20091178 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17594394 0,20081647 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17594394 0,20072125 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17594394 0,20062612 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17594394 0,20053108 ! cell fate specification GO:0001708 52 33 0,000 0,17594394 0,20043614 ! sterol transport GO:0015918 57 33 0,000 0,17594394 0,20034128 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17594394 0,20024651 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17594394 0,20015183 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,17594394 0,20005724 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17594394 0,19996274 ! glial cell differentiation GO:0010001 63 34 0,000 0,1807649 0,20534483 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,1807649 0,20524793 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,1807649 0,20515111 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,1807649 0,20505439 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,1807649 0,20495776 ! mismatch repair GO:0006298 46 34 0,000 0,1807649 0,20486121 ! spermatid development GO:0007286 63 34 0,000 0,1807649 0,20476476 ! placenta development GO:0001890 53 34 0,000 0,1807649 0,2046684 ! regulation of muscle development GO:0048634 70 35 0,000 0,18555782 0,20999629 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,18555782 0,20989756 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18555782 0,20979893 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,18555782 0,20970039 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18555782 0,20960193 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,18555782 0,20950358 ! female gonad development GO:0008585 58 35 0,000 0,18555782 0,20940531 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18555782 0,20930714 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,18555782 0,20920905 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,18555782 0,20911106 ! cytokine production GO:0001816 59 35 0,000 0,18555782 0,20901316 ! neural tube formation GO:0001841 67 35 0,000 0,18555782 0,20891536 ! vesicle localization GO:0051648 64 35 0,000 0,18555782 0,20881764 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,19032286 0,21407985 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19032286 0,21397981 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19032286 0,21387987 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,19032286 0,21378002 ! regulation of proteolysis GO:0030162 72 36 0,000 0,19032286 0,21368026 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19032286 0,2135806 ! aerobic respiration GO:0009060 55 36 0,000 0,19032286 0,21348102 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,19032286 0,21338155 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19506017 0,21859095 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19506017 0,21848919 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19506017 0,21838752 ! tissue remodeling GO:0048771 76 37 0,000 0,19506017 0,21828594 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19506017 0,21818446 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,19506017 0,21808308 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19506017 0,21798178 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19506017 0,21788058 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19506017 0,21777948 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,19506017 0,21767847 ! glycogen metabolic process GO:0005977 61 37 0,000 0,19506017 0,21757755 ! pigment metabolic process GO:0042440 80 37 0,000 0,19506017 0,21747673 ! spermatid differentiation GO:0048515 66 37 0,000 0,19506017 0,217376 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19976993 0,2225215 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,19976993 0,22241853 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19976993 0,22231566 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,19976993 0,22221287 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19976993 0,22211019 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,19976993 0,2220076 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,19976993 0,2219051 ! lipid homeostasis GO:0055088 67 38 0,000 0,19976993 0,2218027 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,19976993 0,22170039 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,19976993 0,22159818 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,19976993 0,22149606 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,19976993 0,22139403 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,19976993 0,2212921 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 0,000 0,19976993 0,22119027 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,20445228 0,22627056 ! learning GO:0007612 77 39 0,000 0,20445228 0,22616652 ! ear morphogenesis GO:0042471 60 39 0,000 0,20445228 0,22606259 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20445228 0,22595874 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,20445228 0,225855 ! segmentation GO:0035282 67 39 0,000 0,20445228 0,22575135 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20445228 0,22564779 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20445228 0,22554433 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,20445228 0,22544097 ! RNA modification GO:0009451 57 39 0,000 0,20445228 0,22533769 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20445228 0,22523452 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20910739 0,23025738 ! negative regulation of binding GO:0051100 72 40 0,000 0,20910739 0,23015205 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21373542 0,23513828 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21373542 0,23503081 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21373542 0,23492344 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,21373542 0,23481617 ! T cell differentiation GO:0030217 81 41 0,000 0,21373542 0,234709 ! female gamete generation GO:0007292 61 41 0,000 0,21373542 0,23460192 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,21833651 0,23954293 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 0,000 0,21833651 0,23943375 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21833651 0,23932467 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,21833651 0,23921569 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21833651 0,2391068 ! neuron migration GO:0001764 79 42 0,000 0,21833651 0,23899802 ! regulation of protein secretion GO:0050708 71 42 0,000 0,21833651 0,23888933 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,21833651 0,23878075 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22291083 0,24367263 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,22291083 0,24356197 ! glucose transport GO:0015758 65 43 0,000 0,22291083 0,24345142 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22291083 0,24334096 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,22291083 0,2432306 ! striated muscle contraction GO:0006941 77 43 0,000 0,22291083 0,24312034 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22291083 0,24301018 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22745854 0,24785564 ! hexose transport GO:0008645 67 44 0,000 0,22745854 0,24774344 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,22745854 0,24763133 ! double-strand break repair GO:0006302 81 44 0,000 0,22745854 0,24751933 ! B cell differentiation GO:0030183 107 44 0,000 0,22745854 0,24740744 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22745854 0,24729564 ! developmental growth GO:0048589 82 44 0,000 0,22745854 0,24718394 ! glycolysis GO:0006096 65 45 0,000 0,23197978 0,25198346 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,23197978 0,25186975 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,23197978 0,25175614 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,23197978 0,25164263 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,23197978 0,25152923 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,23197978 0,25141593 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,23197978 0,25130273 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23647471 0,25605678 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,23647471 0,25594159 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,23647471 0,25582651 ! positive regulation of defense response GO:0031349 76 47 0,000 0,24094348 0,26054383 ! response to calcium ion GO:0051592 81 47 0,000 0,24094348 0,26042679 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,24094348 0,26030984 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,24094348 0,26019301 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24094348 0,26007628 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,24094348 0,25995965 ! JNK cascade GO:0007254 91 47 0,000 0,24094348 0,25984313 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,24094348 0,25972671 ! mitochondrial transport GO:0006839 82 48 0,000 0,24538625 0,26439737 ! Notch signaling pathway GO:0007219 96 48 0,000 0,24538625 0,26427901 ! cellular component disassembly GO:0022411 86 48 0,000 0,24538625 0,26416077 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,24538625 0,26404263 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24538625 0,26392459 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24538625 0,26380667 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,24538625 0,26368884 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,24538625 0,26357112 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24980316 0,26819563 ! regulation of action potential GO:0001508 95 49 0,000 0,24980316 0,268076 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,24980316 0,26795649 ! regulation of ion transport GO:0043269 77 49 0,000 0,24980316 0,26783708 ! peptide metabolic process GO:0006518 76 49 0,000 0,24980316 0,26771777 ! response to temperature stimulus GO:0009266 76 49 0,000 0,24980316 0,26759857 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24980316 0,26747948 ! endocrine system development GO:0035270 104 49 0,000 0,24980316 0,2673605 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,24980316 0,26724162 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24980316 0,26712284 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24980316 0,26700418 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,24980316 0,26688561 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,25419436 0,27145656 ! neuromuscular process GO:0050905 99 50 0,000 0,25419436 0,27133613 ! inner ear development GO:0048839 79 50 0,000 0,25419436 0,2712158 ! histone modification GO:0016570 91 50 0,000 0,25419436 0,27109558 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,25419436 0,27097547 ! positive regulation of binding GO:0051099 78 51 0,000 0,25856 0,27550725 ! viral infectious cycle GO:0019058 99 51 0,000 0,25856 0,27538529 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,25856 0,27526344 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,25856 0,27514169 ! excretion GO:0007588 83 51 0,000 0,25856 0,27502006 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,25856 0,27489853 ! chromatin remodeling GO:0006338 109 51 0,000 0,25856 0,27477711 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,25856 0,27465579 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,25856 0,27453458 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,25856 0,27441348 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,26290024 0,27889681 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,26290024 0,27877389 ! membrane fusion GO:0006944 110 52 0,000 0,26290024 0,27865109 ! covalent chromatin modification GO:0016569 101 52 0,000 0,26290024 0,27852839 ! amino acid activation GO:0043038 92 52 0,000 0,26290024 0,2784058 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,26290024 0,27828331 ! synapse organization GO:0050808 85 52 0,000 0,26290024 0,27816094 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26721521 0,2826021 ! RNA catabolic process GO:0006401 93 53 0,000 0,26721521 0,28247794 ! regulation of translational initiation GO:0006446 82 53 0,000 0,26721521 0,28235388 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26721521 0,28222993 ! response to UV GO:0009411 104 53 0,000 0,26721521 0,28210609 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,27150506 0,28650928 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,27150506 0,28638368 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27150506 0,28625818 ! chloride transport GO:0006821 90 55 0,000 0,27576994 0,29062745 ! glucose catabolic process GO:0006007 82 55 0,000 0,27576994 0,29050021 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,27576994 0,29037307 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27576994 0,29024605 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,27576994 0,29011914 ! aging GO:0007568 103 55 0,000 0,27576994 0,28999234 ! gastrulation GO:0007369 112 55 0,000 0,27576994 0,28986565 ! RNA elongation GO:0006354 79 55 0,000 0,27576994 0,28973907 ! sensory perception of smell GO:0007608 80 56 0,000 0,28000999 0,29406549 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28000999 0,29393719 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,28000999 0,293809 ! regulation of DNA replication GO:0006275 101 56 0,000 0,28000999 0,29368092 ! proton transport GO:0015992 94 56 0,000 0,28000999 0,29355296 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,28422536 0,29784243 ! lipid modification GO:0030258 97 57 0,000 0,28422536 0,29771277 ! hydrogen transport GO:0006818 97 58 0,000 0,28841619 0,301971 ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,29258262 0,3062 ! DNA catabolic process GO:0006308 86 59 0,000 0,29258262 0,30606687 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,29258262 0,30593385 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,2967248 0,31013026 ! camera-type eye development GO:0043010 116 60 0,000 0,2967248 0,3099956 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,2967248 0,30986105 ! kidney development GO:0001822 122 60 0,000 0,2967248 0,30972662 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,30084285 0,31388894 ! mesoderm development GO:0007498 119 61 0,000 0,30084285 0,31375288 ! tRNA processing GO:0008033 89 61 0,000 0,30084285 0,31361694 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30084285 0,31348112 ! ear development GO:0043583 103 62 0,000 0,30493693 0,31760964 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,30493693 0,3174722 ! gonad development GO:0008406 98 62 0,000 0,30493693 0,31733489 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,30493693 0,31719769 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,31305372 0,3255001 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31305372 0,3253595 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,31305372 0,32521901 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,31305372 0,32507865 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,31707669 0,32911412 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,31707669 0,3289722 ! germ cell development GO:0007281 118 65 0,000 0,31707669 0,3288304 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,32107624 0,33283474 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,32107624 0,3326914 ! secondary metabolic process GO:0019748 116 66 0,000 0,32107624 0,33254819 ! cell projection assembly GO:0030031 120 66 0,000 0,32107624 0,3324051 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,3250525 0,33637691 ! hexose catabolic process GO:0019320 104 67 0,000 0,3250525 0,3362323 ! adaptive immune response GO:0002250 119 67 0,000 0,3250525 0,33608781 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,3250525 0,33594344 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,32900561 0,33988299 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,32900561 0,33973712 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,33293569 0,3436479 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,33293569 0,34350054 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,33293569 0,34335331 ! humoral immune response GO:0006959 109 71 0,000 0,34072732 0,35123819 ! B cell activation GO:0042113 160 71 0,000 0,34072732 0,35108776 ! acute inflammatory response GO:0002526 113 72 0,000 0,34458913 0,354915 ! carbohydrate transport GO:0008643 110 72 0,000 0,34458913 0,35476313 ! learning or memory GO:0007611 147 73 0,000 0,34842845 0,35856238 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,34842845 0,35840908 ! axon guidance GO:0007411 139 73 0,000 0,34842845 0,35825592 ! fertilization GO:0009566 90 73 0,000 0,34842845 0,35810288 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,3522454 0,36187124 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,3522454 0,36171679 ! neurotransmitter transport GO:0006836 123 74 0,000 0,3522454 0,36156247 ! exocytosis GO:0006887 133 74 0,000 0,3522454 0,36140829 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,35604012 0,36514601 ! rhythmic process GO:0048511 128 75 0,000 0,35604012 0,36499043 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,35604012 0,36483498 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,35981274 0,36854383 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,35981274 0,368387 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,35981274 0,36823031 ! regulation of catabolic process GO:0009894 161 76 0,000 0,35981274 0,36807375 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36356338 0,37175244 ! blood coagulation GO:0007596 146 78 0,000 0,36729217 0,37540567 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,36729217 0,37524627 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,36729217 0,37508699 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,37099923 0,37871199 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,3746847 0,38231187 ! response to metal ion GO:0010038 140 80 0,000 0,3746847 0,38214981 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,3746847 0,38198788 ! inorganic anion transport GO:0015698 138 80 0,000 0,3746847 0,38182609 ! T cell activation GO:0042110 168 81 0,000 0,3783487 0,38539669 ! digestion GO:0007586 112 81 0,000 0,3783487 0,38523359 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,3783487 0,38507063 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,38199135 0,38861361 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,38199135 0,38844936 ! response to nutrient GO:0007584 125 82 0,000 0,38199135 0,38828525 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,38199135 0,38812128 ! regulation of lyase activity GO:0051339 160 83 0,000 0,38561278 0,39163543 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,3892131 0,3951252 ! hemostasis GO:0007599 158 84 0,000 0,3892131 0,39495855 ! negative regulation of transport GO:0051051 153 84 0,000 0,3892131 0,39479204 ! response to unfolded protein GO:0006986 131 85 0,000 0,39279245 0,3982548 ! nucleosome assembly GO:0006334 122 85 0,000 0,39279245 0,39808704 ! response to inorganic substance GO:0010035 153 86 0,000 0,39635094 0,40152436 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,39635094 0,40135537 ! chromatin assembly GO:0031497 124 86 0,000 0,39635094 0,40118652 ! mitochondrion organization GO:0007005 148 86 0,000 0,39635094 0,40101781 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,39988869 0,40442715 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,40340582 0,40781278 ! regulation of DNA binding GO:0051101 155 88 0,000 0,40340582 0,4076415 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,40340582 0,40747037 ! cellular defense response GO:0006968 114 89 0,000 0,40690246 0,41082976 ! ossification GO:0001503 188 90 0,000 0,41037872 0,41416578 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,41037872 0,41399212 ! sex differentiation GO:0007548 145 90 0,000 0,41037872 0,41381861 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,41037872 0,41364525 ! bone development GO:0060348 189 91 0,000 0,41383473 0,41695408 ! sterol metabolic process GO:0016125 152 91 0,000 0,41383473 0,41677955 ! response to protein stimulus GO:0051789 149 91 0,000 0,41383473 0,41660517 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41383473 0,41643093 ! nucleosome organization GO:0034728 138 92 0,000 0,41727058 0,4197128 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,41727058 0,41953741 ! vitamin metabolic process GO:0006766 139 92 0,000 0,41727058 0,41936217 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,42068642 0,42261859 ! regulation of membrane potential GO:0042391 164 93 0,000 0,42068642 0,4224422 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,42068642 0,42226597 ! female pregnancy GO:0007565 164 94 0,000 0,42408234 0,42549713 ! transcription initiation GO:0006352 153 94 0,000 0,42408234 0,42531976 ! forebrain development GO:0030900 188 95 0,000 0,42745847 0,42852711 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,42745847 0,42834864 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,43081492 0,43153234 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,4341518 0,43469381 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,4341518 0,43451299 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,43746923 0,43765113 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,44076732 0,44076732