pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6574-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 3,000 2,963E-08 6,816E-05 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 2,000 4,226E-07 4,86E-04 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 3,000 5,341E-07 4,094E-04 ! negative regulation of focal adhesion formation GO:0051895 16 6 2,000 8,431E-07 4,848E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 9,863E-07 4,537E-04 ! positive regulation of cell migration GO:0030335 92 51 4,000 9,863E-07 3,781E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 3,000 1,445E-06 4,747E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 2,000 1,472E-06 4,231E-04 ! regulation of focal adhesion formation GO:0051893 17 7 2,000 1,472E-06 3,761E-04 ! positive regulation of cell motion GO:0051272 99 56 4,000 1,582E-06 3,639E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 2,000 2,349E-06 4,911E-04 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,349E-06 4,502E-04 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 2,000 2,349E-06 4,156E-04 ! negative regulation of protein transport GO:0051224 49 27 3,000 2,367E-06 3,889E-04 ! maintenance of protein location in cell GO:0032507 60 31 3,000 4,199E-06 6,439E-04 ! regulation of protein stability GO:0031647 48 32 3,000 4,787E-06 6,881E-04 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 2,000 5,008E-06 6,775E-04 GO:0010812|negative regulation of cell-substrate adhesion, ! cytoplasmic sequestering of protein GO:0051220 14 10 2,000 5,008E-06 6,399E-04 ! cellular response to hormone stimulus GO:0032870 109 74 4,000 6,354E-06 7,691E-04 ! regulation of intracellular protein transport GO:0033157 59 35 3,000 6,914E-06 7,952E-04 ! maintenance of protein location GO:0045185 65 35 3,000 6,914E-06 7,573E-04 ! maintenance of location in cell GO:0051651 69 38 3,000 9,67E-06 1,011E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 1,075E-05 1,075E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 1,451E-05 1,39E-03 ! inositol metabolic process GO:0006020 20 14 2,000 1,504E-05 1,383E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 2,000 1,875E-05 1,659E-03 ! cardiac muscle tissue development GO:0048738 23 15 2,000 1,875E-05 1,597E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 1,916E-05 1,574E-03 ! endothelial cell migration GO:0043542 22 16 2,000 2,302E-05 1,826E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 2,000 2,302E-05 1,765E-03 ! regulation of intracellular transport GO:0032386 78 49 3,000 2,696E-05 2E-03 ! maintenance of location GO:0051235 84 49 3,000 2,696E-05 1,938E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 2,788E-05 1,943E-03 ! negative regulation of intracellular transport GO:0032387 29 17 2,000 2,788E-05 1,886E-03 ! lipid modification GO:0030258 73 50 3,000 2,923E-05 1,921E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 4,639E-05 2,964E-03 ! phosphoinositide metabolic process GO:0030384 87 60 3,000 6,027E-05 3,746E-03 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 6,235E-05 3,774E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of transcription factor import into nucleus GO:0042990 46 23 2,000 7,152E-05 4,218E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 8,153E-05 4,688E-03 ! fat cell differentiation GO:0045444 37 24 2,000 8,153E-05 4,573E-03 ! negative regulation of protein kinase cascade GO:0010741 51 26 2,000 1,042E-04 5,706E-03 ! regulation of catabolic process GO:0009894 106 70 3,000 1,104E-04 5,903E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,229E-04 6,425E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,229E-04 6,282E-03 ! early endosome to late endosome transport GO:0045022 11 5 1,000 1,229E-04 6,145E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,229E-04 6,015E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 1,229E-04 5,889E-03 ! negative regulation of transport GO:0051051 116 73 3,000 1,3E-04 6,1E-03 ! positive regulation of catabolic process GO:0009896 40 28 2,000 1,306E-04 6,009E-03 ! regulation of protein import into nucleus GO:0042306 53 29 2,000 1,453E-04 6,554E-03 ! regulation of protein transport GO:0051223 114 76 3,000 1,52E-04 6,722E-03 GO:0070201|regulation of establishment of protein localization, ! cell fate specification GO:0001708 37 31 2,000 1,779E-04 7,719E-03 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 1,839E-04 7,834E-03 ! mRNA stabilization GO:0048255 15 6 1,000 1,839E-04 7,692E-03 GO:0043489|RNA stabilization, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 1,839E-04 7,555E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of insulin secretion GO:0032024 8 6 1,000 1,839E-04 7,422E-03 ! male sex determination GO:0030238 9 6 1,000 1,839E-04 7,294E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 1,839E-04 7,171E-03 ! regulation of cell adhesion GO:0030155 159 83 3,000 2,137E-04 8,192E-03 ! negative regulation of cell adhesion GO:0007162 67 33 2,000 2,148E-04 8,1E-03 ! carbohydrate homeostasis GO:0033500 39 33 2,000 2,148E-04 7,969E-03 GO:0042593|glucose homeostasis, ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 2,342E-04 8,551E-03 ! regulation of protein localization GO:0032880 132 85 3,000 2,342E-04 8,417E-03 ! polyol metabolic process GO:0019751 44 34 2,000 2,35E-04 8,316E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 2,35E-04 8,19E-03 ! T-helper 1 type immune response GO:0042088 11 7 1,000 2,569E-04 8,82E-03 ! protein heterooligomerization GO:0051291 10 7 1,000 2,569E-04 8,69E-03 ! hormone-mediated signaling GO:0009755 49 36 2,000 2,79E-04 9,3E-03 ! glycerophospholipid metabolic process GO:0006650 130 92 3,000 3,173E-04 0,01042524 ! cell fate commitment GO:0045165 141 92 3,000 3,173E-04 0,01027841 ! DNA synthesis during DNA repair GO:0000731 9 8 1,000 3,418E-04 0,01091821 ! cell proliferation in forebrain GO:0021846 10 8 1,000 3,418E-04 0,01076865 ! induction of positive chemotaxis GO:0050930 14 8 1,000 3,418E-04 0,01062312 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 3,418E-04 0,01048148 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 1,000 3,418E-04 0,01034357 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 3,418E-04 0,01020924 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,418E-04 0,01007835 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 3,418E-04 9,951E-03 ! induction of an organ GO:0001759 11 8 1,000 3,418E-04 9,826E-03 ! regulation of embryonic development GO:0045995 16 8 1,000 3,418E-04 9,705E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 3,418E-04 9,587E-03 ! synapse organization GO:0050808 55 39 2,000 3,544E-04 9,822E-03 ! angiogenesis GO:0001525 149 95 3,000 3,587E-04 9,82E-03 ! regulation of developmental growth GO:0048638 13 9 1,000 4,384E-04 0,01186359 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 4,384E-04 0,01172564 ! regulation of glycolysis GO:0006110 15 9 1,000 4,384E-04 0,01159086 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 1,000 4,384E-04 0,01145915 ! lung alveolus development GO:0048286 17 9 1,000 4,384E-04 0,01133039 ! receptor clustering GO:0043113 15 9 1,000 4,384E-04 0,0112045 ! motor axon guidance GO:0008045 14 9 1,000 4,384E-04 0,01108137 ! positive regulation of peptide secretion GO:0002793 15 9 1,000 4,384E-04 0,01096092 ! regulation of hormone metabolic process GO:0032350 15 9 1,000 4,384E-04 0,01084306 ! nucleus localization GO:0051647 15 9 1,000 4,384E-04 0,01072771 ! localization within membrane GO:0051668 15 9 1,000 4,384E-04 0,01061479 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 4,738E-04 0,01135152 ! response to insulin stimulus GO:0032868 63 43 2,000 4,738E-04 0,0112345 ! negative regulation of cell migration GO:0030336 92 44 2,000 5,072E-04 0,01190345 ! positive regulation of cell cycle GO:0045787 77 45 2,000 5,42E-04 0,01259307 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 5,468E-04 0,01257627 ! blood vessel remodeling GO:0001974 21 10 1,000 5,468E-04 0,01245175 ! regulation of bone resorption GO:0045124 24 10 1,000 5,468E-04 0,01232967 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 5,468E-04 0,01220997 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 5,468E-04 0,01209256 GO:0043470|regulation of carbohydrate catabolic process, ! developmental induction GO:0031128 13 10 1,000 5,468E-04 0,0119774 GO:0045168|cell-cell signaling involved in cell fate specification, ! response to UV GO:0009411 75 46 2,000 5,784E-04 0,01255034 ! regulation of DNA replication GO:0006275 75 48 2,000 6,557E-04 0,0140949 ! virus-host interaction GO:0019048 17 11 1,000 6,668E-04 0,0141999 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 6,668E-04 0,01406962 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 6,668E-04 0,01394172 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 6,668E-04 0,01381611 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 6,668E-04 0,01369276 ! regulation of mRNA processing GO:0050684 18 11 1,000 6,668E-04 0,01357158 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 6,668E-04 0,01345253 ! regulation of leukocyte migration GO:0002685 24 11 1,000 6,668E-04 0,01333555 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 6,668E-04 0,01322059 GO:0042130|negative regulation of T cell proliferation, ! skeletal muscle fiber development GO:0048741 73 50 2,000 7,393E-04 0,01453386 ! muscle fiber development GO:0048747 74 51 2,000 7,836E-04 0,01527283 ! regulation of protein catabolic process GO:0042176 77 51 2,000 7,836E-04 0,01514449 ! negative regulation of cell motion GO:0051271 104 51 2,000 7,836E-04 0,01501829 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 7,983E-04 0,01517442 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 1,000 7,983E-04 0,01505004 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 7,983E-04 0,01492768 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of mRNA stability GO:0043488 27 12 1,000 7,983E-04 0,01480729 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 7,983E-04 0,01468884 ! nucleotide-excision repair GO:0006289 64 52 2,000 8,294E-04 0,01514064 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 9,413E-04 0,01704715 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 9,413E-04 0,01691397 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 9,413E-04 0,01678285 ! regulation of RNA stability GO:0043487 28 13 1,000 9,413E-04 0,01665376 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 1,084E-03 0,01903956 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,096E-03 0,01909133 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 1,096E-03 0,01894778 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 1,096E-03 0,01880638 ! lung development GO:0030324 94 59 2,000 1,199E-03 0,02042383 ! lipid phosphorylation GO:0046834 23 15 1,000 1,261E-03 0,02133178 ! myoblast differentiation GO:0045445 27 15 1,000 1,261E-03 0,02117607 ! cerebral cortex development GO:0021987 29 15 1,000 1,261E-03 0,02102262 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,261E-03 0,02087138 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 1,261E-03 0,0207223 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! respiratory tube development GO:0030323 99 62 2,000 1,384E-03 0,02257829 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,438E-03 0,02329581 ! cellular response to unfolded protein GO:0034620 19 16 1,000 1,438E-03 0,0231329 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,438E-03 0,02297225 ! respiratory system development GO:0060541 100 64 2,000 1,517E-03 0,0240656 ! positive regulation of hormone secretion GO:0046887 24 17 1,000 1,626E-03 0,02562002 ! signal complex assembly GO:0007172 29 17 1,000 1,626E-03 0,02544573 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 1,626E-03 0,0252738 ! neuromuscular junction development GO:0007528 23 17 1,000 1,626E-03 0,02510418 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 1,626E-03 0,02493682 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 1,626E-03 0,02477167 ! axon guidance GO:0007411 99 66 2,000 1,658E-03 0,02508775 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,825E-03 0,02744113 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 1,825E-03 0,02726295 ! pancreas development GO:0031016 26 18 1,000 1,825E-03 0,02708706 ! negative regulation of T cell activation GO:0050868 25 18 1,000 1,825E-03 0,02691342 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 1,963E-03 0,02876453 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 2,036E-03 0,02963125 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 2,036E-03 0,02944489 GO:0010675|regulation of cellular carbohydrate metabolic process, ! sex determination GO:0007530 29 19 1,000 2,036E-03 0,02926086 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 2,036E-03 0,02907912 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 2,036E-03 0,02889962 ! protein stabilization GO:0050821 26 19 1,000 2,036E-03 0,02872232 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 2,045E-03 0,02867947 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 2,129E-03 0,02967038 GO:0045937|positive regulation of phosphate metabolic process, ! pallium development GO:0021543 38 20 1,000 2,257E-03 0,03126553 ! positive regulation of locomotion GO:0040017 35 20 1,000 2,257E-03 0,03107831 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 36 21 1,000 2,488E-03 0,03406746 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,488E-03 0,03386587 ! regulation of insulin secretion GO:0050796 26 21 1,000 2,488E-03 0,03366666 ! vasculogenesis GO:0001570 33 22 1,000 2,731E-03 0,0367329 ! regulation of behavior GO:0050795 38 22 1,000 2,731E-03 0,03651934 ! protein tetramerization GO:0051262 39 22 1,000 2,731E-03 0,03630824 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 2,984E-03 0,0394476 ! myelination GO:0042552 35 23 1,000 2,984E-03 0,03922219 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 2,984E-03 0,03899933 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 2,984E-03 0,038779 ! interaction with host GO:0051701 37 23 1,000 2,984E-03 0,03856114 ! negative regulation of catabolic process GO:0009895 34 23 1,000 2,984E-03 0,03834571 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 3,248E-03 0,04150459 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 3,248E-03 0,04127528 ! receptor metabolic process GO:0043112 37 24 1,000 3,248E-03 0,04104849 ! base-excision repair GO:0006284 31 24 1,000 3,248E-03 0,04082418 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 3,248E-03 0,04060231 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 3,412E-03 0,04241793 ! regulation of peptide secretion GO:0002791 34 25 1,000 3,523E-03 0,04355904 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 3,523E-03 0,0433261 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 3,523E-03 0,04309564 ! cell cycle arrest GO:0007050 150 86 2,000 3,526E-03 0,04291316 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 3,526E-03 0,04268731 ! skeletal muscle tissue development GO:0007519 123 87 2,000 3,643E-03 0,04387023 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 3,643E-03 0,04364174 ! interphase GO:0051325 159 88 2,000 3,762E-03 0,04483537 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 3,807E-03 0,04514007 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 3,807E-03 0,04490859 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 4,103E-03 0,04814405 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 4,103E-03 0,04789966 GO:0043433|negative regulation of transcription factor activity, ! mesoderm formation GO:0001707 46 28 1,000 4,408E-03 0,051207 ! ensheathment of neurons GO:0007272 43 28 1,000 4,408E-03 0,05094968 GO:0008366|axon ensheathment, ! mismatch repair GO:0006298 34 29 1,000 4,724E-03 0,05432631 ! formation of primary germ layer GO:0001704 48 29 1,000 4,724E-03 0,05405603 ! telencephalon development GO:0021537 52 29 1,000 4,724E-03 0,05378843 ! tissue homeostasis GO:0001894 42 29 1,000 4,724E-03 0,05352346 GO:0048871|multicellular organismal homeostasis, ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 4,801E-03 0,05413326 ! response to light stimulus GO:0009416 153 96 2,000 4,801E-03 0,05386919 ! spindle organization GO:0007051 37 30 1,000 5,05E-03 0,05638296 ! regulation of microtubule-based process GO:0032886 58 30 1,000 5,05E-03 0,05611058 ! negative regulation of cell activation GO:0050866 44 30 1,000 5,05E-03 0,05584082 ! extracellular structure organization GO:0043062 156 99 2,000 5,231E-03 0,05756998 ! mammary gland development GO:0030879 57 31 1,000 5,386E-03 0,05898905 ! odontogenesis GO:0042476 50 31 1,000 5,386E-03 0,05870949 ! mesoderm morphogenesis GO:0048332 49 31 1,000 5,386E-03 0,05843255 ! peripheral nervous system development GO:0007422 53 32 1,000 5,732E-03 0,06189449 ! calcium-mediated signaling GO:0019722 50 32 1,000 5,732E-03 0,06160527 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 5,732E-03 0,06131873 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 6,088E-03 0,064825 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 6,088E-03 0,06452627 ! negative regulation of DNA binding GO:0043392 54 33 1,000 6,088E-03 0,06423028 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 6,088E-03 0,06393699 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 6,454E-03 0,0674707 ! regulation of action potential in neuron GO:0019228 54 35 1,000 6,829E-03 0,07107431 ! regulation of hormone secretion GO:0046883 48 36 1,000 7,215E-03 0,07474613 ! negative regulation of binding GO:0051100 58 36 1,000 7,215E-03 0,07441094 ! tissue remodeling GO:0048771 62 36 1,000 7,215E-03 0,07407875 ! regulation of T cell proliferation GO:0042129 58 38 1,000 8,014E-03 0,08192209 ! mesenchymal cell development GO:0014031 64 38 1,000 8,014E-03 0,0815596 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 8,428E-03 0,0853954 ! cell growth GO:0016049 61 39 1,000 8,428E-03 0,08502085 ! response to calcium ion GO:0051592 58 40 1,000 8,852E-03 0,08890279 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 8,852E-03 0,08851626 ! positive regulation of protein transport GO:0051222 55 40 1,000 8,852E-03 0,08813307 ! endosome transport GO:0016197 71 41 1,000 9,284E-03 0,09204422 ! regulation of T cell differentiation GO:0045580 59 41 1,000 9,284E-03 0,09164919 ! regulation of cell shape GO:0008360 78 42 1,000 9,727E-03 0,09560324 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,01017795 0,09961394 ! regulation of action potential GO:0001508 71 44 1,000 0,01063846 0,10367989 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,01063846 0,10324243 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,01110806 0,10734679 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,01207425 0,11619574 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,01207425 0,11571159 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! gastrulation GO:0007369 73 48 1,000 0,01257071 0,11996944 ! heart morphogenesis GO:0003007 65 48 1,000 0,01257071 0,1194737 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,01257071 0,11898203 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,01307599 0,12325725 ! positive regulation of growth GO:0045927 67 50 1,000 0,01359001 0,12757972 ! positive regulation of secretion GO:0051047 71 51 1,000 0,01411273 0,13194825 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01411273 0,13141405 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,01464406 0,13581182 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,01518394 0,14025328 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01573231 0,1447373 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,01573231 0,14416065 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01573231 0,14358859 ! mesoderm development GO:0007498 76 55 1,000 0,01628911 0,14808283 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01760919 0,15945333 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01760919 0,15882802 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01760919 0,1582076 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01760919 0,157592 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01760919 0,15698118 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01760919 0,15637508 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01760919 0,15577364 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01760919 0,1551768 ! sleep GO:0030431 11 5 0,000 0,01760919 0,15458452 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01760919 0,15399675 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01760919 0,15341343 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01760919 0,15283451 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01760919 0,15225994 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01760919 0,15168968 ! tongue development GO:0043586 6 5 0,000 0,01760919 0,15112368 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01760919 0,15056188 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01760919 0,15000424 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01760919 0,14945072 ! cobalt ion transport GO:0006824 9 5 0,000 0,01760919 0,14890127 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01760919 0,14835584 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01760919 0,1478144 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01760919 0,14727689 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01760919 0,14674328 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01760919 0,14621352 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01760919 0,14568757 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01760919 0,14516539 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01760919 0,14464695 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01760919 0,14413219 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01760919 0,14362108 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01760919 0,14311359 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01760919 0,14260967 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01760919 0,14210928 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01760919 0,1416124 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01760919 0,14111897 ! malate metabolic process GO:0006108 7 5 0,000 0,01760919 0,14062898 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01760919 0,14014237 ! behavioral response to pain GO:0048266 7 5 0,000 0,01760919 0,13965912 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01760919 0,13917919 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01760919 0,13870255 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01760919 0,13822916 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01760919 0,137759 ! mating behavior GO:0007617 6 5 0,000 0,01760919 0,13729202 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01760919 0,13682819 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01760919 0,13636749 ! rhythmic behavior GO:0007622 12 5 0,000 0,01760919 0,13590988 ! copulation GO:0007620 7 5 0,000 0,01760919 0,13545534 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01760919 0,13500382 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01760919 0,1345553 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01760919 0,13410975 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01760919 0,13366715 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01760919 0,13322745 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01760919 0,13279064 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01760919 0,13235668 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01760919 0,13192555 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01760919 0,13149722 ! response to protozoan GO:0001562 9 5 0,000 0,01760919 0,13107167 ! lymph vessel development GO:0001945 7 5 0,000 0,01760919 0,13064886 ! endochondral ossification GO:0001958 12 5 0,000 0,01760919 0,13022876 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01760919 0,12981136 ! parathyroid gland development GO:0060017 8 5 0,000 0,01760919 0,12939663 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01760919 0,12898454 ! anagen GO:0042640 6 5 0,000 0,01760919 0,12857506 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01760919 0,12816818 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01760919 0,12776386 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01760919 0,12736209 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01760919 0,12696284 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01760919 0,12656608 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01760919 0,12617179 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01760919 0,12577995 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01760919 0,12539054 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01760919 0,12500353 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01760919 0,12461891 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01760919 0,12423664 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01760919 0,12385671 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01760919 0,1234791 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01760919 0,12310378 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01760919 0,12273074 ! ovulation GO:0030728 6 5 0,000 0,01760919 0,12235996 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01760919 0,1219914 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01760919 0,12162506 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01760919 0,12126091 ! response to pH GO:0009268 9 5 0,000 0,01760919 0,12089894 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01760919 0,12053912 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01760919 0,12018144 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01760919 0,11982587 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01760919 0,1194724 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01760919 0,11912102 ! polyol catabolic process GO:0046174 7 5 0,000 0,01760919 0,11877169 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01760919 0,1184244 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01760919 0,11807914 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01760919 0,11773589 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01760919 0,11739462 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01760919 0,11705533 ! urea metabolic process GO:0019627 6 5 0,000 0,01760919 0,116718 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01760919 0,1163826 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01760919 0,11604913 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01760919 0,11571756 ! neutrophil activation GO:0042119 5 5 0,000 0,01760919 0,11538788 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01760919 0,11506007 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01760919 0,11473412 ! response to food GO:0032094 5 5 0,000 0,01760919 0,11441001 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01760919 0,11408773 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01760919 0,11376726 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01760919 0,11344859 ! forebrain neuron development GO:0021884 7 5 0,000 0,01760919 0,11313169 ! melanosome organization GO:0032438 7 5 0,000 0,01760919 0,11281656 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01760919 0,11250318 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01760919 0,11219154 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01760919 0,11188162 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01760919 0,1115734 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01760919 0,11126688 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01760919 0,11096204 ! nucleoside transport GO:0015858 6 5 0,000 0,01760919 0,11065887 ! nucleoside salvage GO:0043174 7 5 0,000 0,01760919 0,11035734 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01760919 0,11005746 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01760919 0,1097592 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01760919 0,10946255 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01760919 0,10916751 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01760919 0,10887405 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01760919 0,10858216 ! depyrimidination GO:0045008 8 5 0,000 0,01760919 0,10829183 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01760919 0,10800305 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01760919 0,10771581 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01760919 0,10743009 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01760919 0,10714589 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01760919 0,10686318 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01760919 0,10658196 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01760919 0,10630222 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01760919 0,10602394 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01760919 0,10574712 ! monocyte differentiation GO:0030224 8 5 0,000 0,01760919 0,10547173 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01760919 0,10519778 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01760919 0,10492525 ! centrosome duplication GO:0051298 5 5 0,000 0,01760919 0,10465412 ! response to UV-C GO:0010225 6 5 0,000 0,01760919 0,10438439 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01760919 0,10411605 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01760919 0,10384909 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01760919 0,10358349 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01760919 0,10331925 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01760919 0,10305635 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01760919 0,10279478 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01760919 0,10253454 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01760919 0,10227562 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01760919 0,102018 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01760919 0,10176167 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01760919 0,10150663 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01760919 0,10125286 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01760919 0,10100036 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01760919 0,10074912 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01760919 0,10049912 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01760919 0,10025036 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01760919 0,10000283 ! neural tube patterning GO:0021532 6 5 0,000 0,01760919 0,09975652 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01760919 0,09951141 ! histone demethylation GO:0016577 9 5 0,000 0,01760919 0,09926751 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01760919 0,0990248 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01760919 0,09878328 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01760919 0,09854293 ! enteric nervous system development GO:0048484 8 5 0,000 0,01760919 0,09830375 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01760919 0,09806573 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01760919 0,09782885 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01760919 0,09759312 ! transcription termination GO:0006353 8 5 0,000 0,01760919 0,09735852 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01760919 0,09712505 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01760919 0,09689269 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01760919 0,09666144 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01760919 0,0964313 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01760919 0,09620225 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01760919 0,09597428 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01760919 0,09574739 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01760919 0,09552157 ! apical protein localization GO:0045176 6 5 0,000 0,01760919 0,09529681 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01760919 0,09507311 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01760919 0,09485046 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01760919 0,09462884 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01760919 0,09440826 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01760919 0,09418871 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01760919 0,09397017 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01760919 0,09375265 ! glial cell migration GO:0008347 10 5 0,000 0,01760919 0,09353613 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01760919 0,09332061 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01760919 0,09310608 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01760919 0,09289253 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01760919 0,09267997 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01760919 0,09246837 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01760919 0,09225773 ! neural plate development GO:0001840 6 5 0,000 0,01760919 0,09204806 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01760919 0,09183933 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01760919 0,09163155 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01760919 0,09142471 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01760919 0,0912188 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01760919 0,09101381 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01760919 0,09080974 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01760919 0,09060659 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01760919 0,09040434 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01760919 0,090203 ! spindle assembly GO:0051225 5 5 0,000 0,01760919 0,09000254 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01760919 0,08980298 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01760919 0,0896043 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01760919 0,0894065 ! organ regeneration GO:0031100 7 5 0,000 0,01760919 0,08920957 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01760919 0,08901351 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01760919 0,0888183 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01760919 0,08862395 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01760919 0,08843045 GO:0055081|anion homeostasis, ! viral reproductive process GO:0022415 87 58 1,000 0,01800939 0,09024315 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,01800939 0,09004696 ! activation of MAPK activity GO:0000187 84 59 1,000 0,01859924 0,09279447 ! actin filament organization GO:0007015 95 59 1,000 0,01859924 0,09259361 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,01919719 0,095364 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,01919719 0,09515847 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,02041715 0,10098803 ! organelle localization GO:0051640 96 62 1,000 0,02041715 0,10077132 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02103903 0,10361834 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,02103903 0,10339694 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,02103903 0,10317647 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,02103903 0,10295695 ! viral reproduction GO:0016032 92 63 1,000 0,02103903 0,10273836 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02103903 0,10252069 ! tRNA transcription GO:0009304 11 6 0,000 0,02109424 0,10257243 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02109424 0,10235604 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02109424 0,10214055 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02109424 0,10192597 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02109424 0,10171229 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02109424 0,1014995 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02109424 0,1012876 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02109424 0,10107659 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02109424 0,10086645 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02109424 0,10065718 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02109424 0,10044878 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02109424 0,10024124 ! prostate gland development GO:0030850 9 6 0,000 0,02109424 0,10003456 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02109424 0,09982873 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02109424 0,09962374 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02109424 0,09941959 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02109424 0,09921628 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02109424 0,0990138 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02109424 0,09881214 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02109424 0,0986113 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02109424 0,09841128 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02109424 0,09821207 ! neuron adhesion GO:0007158 9 6 0,000 0,02109424 0,09801366 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,02109424 0,09781605 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02109424 0,09761924 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02109424 0,09742322 ! signal peptide processing GO:0006465 8 6 0,000 0,02109424 0,09722798 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02109424 0,09703352 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02109424 0,09683984 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02109424 0,09664694 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02109424 0,09645479 ! opsonization GO:0008228 8 6 0,000 0,02109424 0,09626342 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02109424 0,0960728 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02109424 0,09588293 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02109424 0,09569381 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02109424 0,09550544 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02109424 0,0953178 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02109424 0,09513091 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02109424 0,09494474 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02109424 0,0947593 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02109424 0,09457458 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02109424 0,09439059 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02109424 0,0942073 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02109424 0,09402473 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02109424 0,09384287 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02109424 0,0936617 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02109424 0,09348124 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02109424 0,09330146 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02109424 0,09312238 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02109424 0,09294399 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02109424 0,09276627 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02109424 0,09258924 ! thymic T cell selection GO:0045061 12 6 0,000 0,02109424 0,09241288 ! protein lipoylation GO:0009249 10 6 0,000 0,02109424 0,09223719 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02109424 0,09206217 ! pigment granule organization GO:0048753 11 6 0,000 0,02109424 0,09188781 ! drug transport GO:0015893 6 6 0,000 0,02109424 0,09171411 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02109424 0,09154106 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02109424 0,09136867 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02109424 0,09119692 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02109424 0,09102582 ! histidine metabolic process GO:0006547 6 6 0,000 0,02109424 0,09085536 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02109424 0,09068554 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02109424 0,09051635 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,02109424 0,09034779 ! adenohypophysis development GO:0021984 10 6 0,000 0,02109424 0,09017985 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02109424 0,09001254 ! hyperosmotic response GO:0006972 8 6 0,000 0,02109424 0,08984585 ! microtubule nucleation GO:0007020 10 6 0,000 0,02109424 0,08967978 ! ER overload response GO:0006983 7 6 0,000 0,02109424 0,08951432 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02109424 0,08934947 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02109424 0,08918522 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02109424 0,08902158 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02109424 0,08885854 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02109424 0,08869609 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02109424 0,08853424 ! response to dietary excess GO:0002021 7 6 0,000 0,02109424 0,08837297 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02109424 0,08821229 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02109424 0,0880522 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02109424 0,08789268 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02109424 0,08773375 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02109424 0,08757538 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02109424 0,08741759 ! neuron apoptosis GO:0051402 8 6 0,000 0,02109424 0,08726036 ! organic alcohol transport GO:0015850 9 6 0,000 0,02109424 0,0871037 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02109424 0,0869476 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02109424 0,08679206 ! carnitine transport GO:0015879 8 6 0,000 0,02109424 0,08663707 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02109424 0,08648264 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02109424 0,08632876 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02109424 0,08617542 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02109424 0,08602263 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02109424 0,08587037 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02109424 0,08571866 ! parturition GO:0007567 12 6 0,000 0,02109424 0,08556748 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02109424 0,08541683 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02109424 0,08526672 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02109424 0,08511713 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02109424 0,08496806 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02109424 0,08481951 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02109424 0,08467149 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02109424 0,08452398 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02109424 0,08437698 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02109424 0,08423049 ! macrophage differentiation GO:0030225 10 6 0,000 0,02109424 0,08408451 ! astrocyte development GO:0014002 14 6 0,000 0,02109424 0,08393903 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02109424 0,08379406 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02109424 0,08364959 ! interaction with symbiont GO:0051702 8 6 0,000 0,02109424 0,08350561 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02109424 0,08336213 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02109424 0,08321915 ! eating behavior GO:0042755 6 6 0,000 0,02109424 0,08307665 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02109424 0,08293464 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02109424 0,08279311 ! response to copper ion GO:0046688 9 6 0,000 0,02109424 0,08265206 ! DNA topological change GO:0006265 8 6 0,000 0,02109424 0,0825115 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02109424 0,08237141 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02109424 0,0822318 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02109424 0,08209266 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02109424 0,08195399 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02109424 0,08181579 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02109424 0,08167805 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02109424 0,08154078 ! gas homeostasis GO:0033483 11 6 0,000 0,02109424 0,08140396 ! hair follicle maturation GO:0048820 7 6 0,000 0,02109424 0,08126761 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02109424 0,08113171 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02109424 0,08099626 ! Schwann cell development GO:0014044 14 6 0,000 0,02109424 0,08086127 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02109424 0,08072672 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02109424 0,08059263 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02109424 0,08045897 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02109424 0,08032576 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02109424 0,08019299 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02109424 0,08006066 ! histone ubiquitination GO:0016574 7 6 0,000 0,02109424 0,07992877 ! regulation of meiosis GO:0040020 10 6 0,000 0,02109424 0,07979731 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02109424 0,07966628 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02109424 0,07953567 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02109424 0,0794055 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02109424 0,07927575 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02109424 0,07914643 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02109424 0,07901753 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02109424 0,07888904 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02109424 0,07876098 ! receptor internalization GO:0031623 9 6 0,000 0,02109424 0,07863333 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02109424 0,07850609 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02109424 0,07837926 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02109424 0,07825284 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02109424 0,07812683 ! protein deubiquitination GO:0016579 8 6 0,000 0,02109424 0,07800122 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02109424 0,07787602 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02109424 0,07775122 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02109424 0,07762682 ! axonal fasciculation GO:0007413 9 6 0,000 0,02109424 0,07750281 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02109424 0,07737921 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02109424 0,07725599 ! midbrain development GO:0030901 6 6 0,000 0,02109424 0,07713317 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02109424 0,07701073 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02109424 0,07688869 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02109424 0,07676703 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02109424 0,07664575 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02109424 0,07652486 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02109424 0,07640435 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02109424 0,07628422 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02109424 0,07616446 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02109424 0,07604508 ! adult feeding behavior GO:0008343 6 6 0,000 0,02109424 0,07592607 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02109424 0,07580744 ! blastocyst growth GO:0001832 15 6 0,000 0,02109424 0,07568918 ! pigment granule transport GO:0051904 12 6 0,000 0,02109424 0,07557128 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02109424 0,07545375 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02109424 0,07533659 ! catecholamine transport GO:0051937 7 6 0,000 0,02109424 0,07521979 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02109424 0,07510335 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02109424 0,07498727 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02109424 0,07487155 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02109424 0,07475618 ! protein prenylation GO:0018342 10 6 0,000 0,02109424 0,07464117 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02109424 0,07452652 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02109424 0,07441221 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02109424 0,07429826 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02109424 0,07418465 ! negative regulation of cell size GO:0045792 108 64 1,000 0,02166877 0,0760888 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,02166877 0,07597281 ! adaptive immune response GO:0002250 94 64 1,000 0,02166877 0,07585717 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! protein oligomerization GO:0051259 100 65 1,000 0,02230629 0,07797033 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,02426502 0,08468825 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02456713 0,08561273 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02456713 0,08548321 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02456713 0,08535408 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02456713 0,08522534 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02456713 0,08509699 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02456713 0,08496902 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02456713 0,08484144 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02456713 0,08471424 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02456713 0,08458742 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02456713 0,08446099 ! reproductive behavior GO:0019098 12 7 0,000 0,02456713 0,08433492 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02456713 0,08420924 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02456713 0,08408393 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02456713 0,08395899 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02456713 0,08383442 ! oligopeptide transport GO:0006857 11 7 0,000 0,02456713 0,08371022 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02456713 0,08358639 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02456713 0,08346292 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02456713 0,08333982 ! RNA methylation GO:0001510 11 7 0,000 0,02456713 0,08321708 ! pericardium development GO:0060039 8 7 0,000 0,02456713 0,08309471 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02456713 0,08297269 ! fibril organization GO:0043206 13 7 0,000 0,02456713 0,08285103 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02456713 0,08272972 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02456713 0,08260877 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02456713 0,08248817 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02456713 0,08236793 ! lipoprotein transport GO:0042953 9 7 0,000 0,02456713 0,08224803 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02456713 0,08212849 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02456713 0,08200929 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02456713 0,08189043 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02456713 0,08177192 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02456713 0,08165376 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02456713 0,08153593 ! chemosensory behavior GO:0007635 9 7 0,000 0,02456713 0,08141844 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02456713 0,08130129 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02456713 0,08118448 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02456713 0,08106801 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02456713 0,08095186 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02456713 0,08083605 ! reflex GO:0060004 12 7 0,000 0,02456713 0,08072057 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02456713 0,08060542 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02456713 0,0804906 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02456713 0,0803761 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02456713 0,08026193 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02456713 0,08014808 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02456713 0,08003456 ! spinal cord patterning GO:0021511 7 7 0,000 0,02456713 0,07992136 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02456713 0,07980847 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02456713 0,07969591 ! adrenal gland development GO:0030325 17 7 0,000 0,02456713 0,07958366 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02456713 0,07947173 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02456713 0,07936011 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02456713 0,07924881 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02456713 0,07913781 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02456713 0,07902713 ! endosome organization GO:0007032 10 7 0,000 0,02456713 0,07891676 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02456713 0,07880669 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02456713 0,07869694 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02456713 0,07858748 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02456713 0,07847833 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02456713 0,07836949 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02456713 0,07826094 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02456713 0,0781527 ! galactose metabolic process GO:0006012 10 7 0,000 0,02456713 0,07804475 ! vesicle fusion GO:0006906 15 7 0,000 0,02456713 0,0779371 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02456713 0,07782975 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02456713 0,0777227 ! organ growth GO:0035265 11 7 0,000 0,02456713 0,07761593 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02456713 0,07750946 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02456713 0,07740329 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02456713 0,0772974 ! retinol metabolic process GO:0042572 9 7 0,000 0,02456713 0,0771918 ! behavioral fear response GO:0001662 13 7 0,000 0,02456713 0,07708649 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02456713 0,07698147 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02456713 0,07687673 ! rRNA modification GO:0000154 12 7 0,000 0,02456713 0,07677228 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02456713 0,07666811 ! response to UV-B GO:0010224 11 7 0,000 0,02456713 0,07656423 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,02456713 0,07646062 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02456713 0,0763573 ! intermediate filament organization GO:0045109 11 7 0,000 0,02456713 0,07625425 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02456713 0,07615148 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02456713 0,07604899 ! fibrinolysis GO:0042730 9 7 0,000 0,02456713 0,07594677 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02456713 0,07584483 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02456713 0,07574316 ! B cell lineage commitment GO:0002326 17 7 0,000 0,02456713 0,07564177 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02456713 0,07554064 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02456713 0,07543979 ! response to tropane GO:0014073 13 7 0,000 0,02456713 0,0753392 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02456713 0,07523888 ! melanosome localization GO:0032400 10 7 0,000 0,02456713 0,07513883 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02456713 0,07503904 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02456713 0,07493952 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02456713 0,07484026 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02456713 0,07474127 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02456713 0,07464254 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02456713 0,07454406 ! mast cell activation GO:0045576 9 7 0,000 0,02456713 0,07444585 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02456713 0,07434789 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02456713 0,0742502 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02456713 0,07415276 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02456713 0,07405557 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02456713 0,07395864 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02456713 0,07386196 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02456713 0,07376553 ! T cell lineage commitment GO:0002360 12 7 0,000 0,02456713 0,07366936 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02456713 0,07357344 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02456713 0,07347776 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02456713 0,07338234 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02456713 0,07328716 ! response to tumor cell GO:0002347 12 7 0,000 0,02456713 0,07319223 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02456713 0,07309754 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02456713 0,0730031 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02456713 0,0729089 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02456713 0,07281495 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02456713 0,07272124 ! diuresis GO:0030146 12 7 0,000 0,02456713 0,07262776 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02456713 0,07253453 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02456713 0,07244154 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02456713 0,07234878 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02456713 0,07225627 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02456713 0,07216398 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02456713 0,07207194 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02456713 0,07198013 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02456713 0,07188855 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02456713 0,0717972 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02456713 0,07170609 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02456713 0,07161521 ! lymph node development GO:0048535 9 7 0,000 0,02456713 0,07152456 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02456713 0,07143413 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02456713 0,07134394 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02456713 0,07125397 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02456713 0,07116423 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02456713 0,07107472 ! ATP catabolic process GO:0006200 10 7 0,000 0,02456713 0,07098543 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02456713 0,07089636 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02456713 0,07080752 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02456713 0,0707189 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02456713 0,0706305 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02456713 0,07054232 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02456713 0,07045436 ! muscle adaptation GO:0043500 12 7 0,000 0,02456713 0,07036662 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02456713 0,0702791 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02456713 0,0701918 ! retina homeostasis GO:0001895 9 7 0,000 0,02456713 0,07010471 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02456713 0,07001784 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02456713 0,06993119 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02456713 0,06984475 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02456713 0,06975852 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02456713 0,0696725 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02456713 0,0695867 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02456713 0,06950111 ! response to metal ion GO:0010038 103 70 1,000 0,02560869 0,0723587 ! muscle cell differentiation GO:0042692 104 71 1,000 0,0262917 0,07419742 ! response to hypoxia GO:0001666 132 72 1,000 0,02698207 0,07605241 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02802789 0,07890349 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02802789 0,07880704 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02802789 0,07871081 ! axon extension GO:0048675 11 8 0,000 0,02802789 0,07861482 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02802789 0,07851907 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02802789 0,07842355 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02802789 0,07832826 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02802789 0,0782332 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02802789 0,07813837 ! phosphate transport GO:0006817 10 8 0,000 0,02802789 0,07804377 ! N-glycan processing GO:0006491 12 8 0,000 0,02802789 0,0779494 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02802789 0,07785526 ! UTP metabolic process GO:0046051 8 8 0,000 0,02802789 0,07776135 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02802789 0,07766766 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02802789 0,07757419 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02802789 0,07748096 ! succinate metabolic process GO:0006105 14 8 0,000 0,02802789 0,07738794 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02802789 0,07729515 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02802789 0,07720258 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02802789 0,07711023 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02802789 0,07701811 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02802789 0,0769262 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02802789 0,07683451 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02802789 0,07674304 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02802789 0,07665179 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02802789 0,07656075 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02802789 0,07646993 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02802789 0,07637933 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02802789 0,07628894 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02802789 0,07619876 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02802789 0,0761088 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02802789 0,07601905 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02802789 0,07592951 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02802789 0,07584018 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02802789 0,07575106 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02802789 0,07566215 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02802789 0,07557345 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02802789 0,07548496 ! melanin metabolic process GO:0006582 12 8 0,000 0,02802789 0,07539667 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02802789 0,07530859 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02802789 0,07522072 ! macrophage activation GO:0042116 12 8 0,000 0,02802789 0,07513305 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02802789 0,07504558 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02802789 0,07495832 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02802789 0,07487126 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02802789 0,0747844 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02802789 0,07469775 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02802789 0,07461129 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02802789 0,07452503 ! ruffle organization GO:0031529 11 8 0,000 0,02802789 0,07443898 ! osteoblast development GO:0002076 13 8 0,000 0,02802789 0,07435312 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02802789 0,07426746 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02802789 0,074182 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02802789 0,07409673 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02802789 0,07401166 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02802789 0,07392678 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02802789 0,0738421 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02802789 0,07375761 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02802789 0,07367332 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02802789 0,07358922 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02802789 0,07350531 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02802789 0,07342159 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02802789 0,07333806 ! segment specification GO:0007379 10 8 0,000 0,02802789 0,07325472 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02802789 0,07317157 ! cellular extravasation GO:0045123 11 8 0,000 0,02802789 0,07308861 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02802789 0,07300584 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02802789 0,07292325 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02802789 0,07284085 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02802789 0,07275864 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02802789 0,07267661 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02802789 0,07259477 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02802789 0,07251311 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02802789 0,07243163 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02802789 0,07235034 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02802789 0,07226923 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02802789 0,0721883 ! icosanoid secretion GO:0032309 12 8 0,000 0,02802789 0,07210756 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02802789 0,07202699 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02802789 0,0719466 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02802789 0,07186639 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02802789 0,07178636 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02802789 0,07170651 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02802789 0,07162684 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02802789 0,07154734 ! sterol catabolic process GO:0016127 9 8 0,000 0,02802789 0,07146802 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02802789 0,07138888 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02802789 0,07130991 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02802789 0,07123111 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02802789 0,07115249 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02802789 0,07107404 ! prophase GO:0051324 11 8 0,000 0,02802789 0,07099577 ! S phase GO:0051320 8 8 0,000 0,02802789 0,07091766 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02802789 0,07083973 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02802789 0,07076197 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02802789 0,07068438 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02802789 0,07060696 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02802789 0,07052971 ! hormone catabolic process GO:0042447 13 8 0,000 0,02802789 0,07045263 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02802789 0,07037572 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02802789 0,07029897 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02802789 0,07022239 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02802789 0,07014598 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02802789 0,07006973 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02802789 0,06999365 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02802789 0,06991774 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02802789 0,06984199 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02802789 0,0697664 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02802789 0,06969098 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02802789 0,06961572 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02802789 0,06954062 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02802789 0,06946568 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02802789 0,06939091 ! response to oxygen levels GO:0070482 137 74 1,000 0,0283847 0,07019872 ! response to inorganic substance GO:0010035 115 75 1,000 0,02909683 0,07188261 ! negative regulation of growth GO:0045926 123 75 1,000 0,02909683 0,07180548 ! response to unfolded protein GO:0006986 99 76 1,000 0,0298161 0,07350164 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,0298161 0,07342294 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,03054245 0,07513115 ! regulation of DNA binding GO:0051101 119 77 1,000 0,03054245 0,07505088 ! gland development GO:0048732 148 77 1,000 0,03054245 0,07497079 ! protein ubiquitination GO:0016567 125 77 1,000 0,03054245 0,07489086 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,03127581 0,07660742 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,03127581 0,07652592 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03147658 0,07693531 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03147658 0,07685363 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03147658 0,07677214 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03147658 0,07669081 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03147658 0,07660965 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03147658 0,07652867 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03147658 0,07644786 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03147658 0,07636722 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03147658 0,07628675 ! GTP metabolic process GO:0046039 9 9 0,000 0,03147658 0,07620645 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03147658 0,07612631 ! social behavior GO:0035176 14 9 0,000 0,03147658 0,07604635 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03147658 0,07596655 ! artery development GO:0060840 19 9 0,000 0,03147658 0,07588692 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03147658 0,07580746 ! response to pain GO:0048265 16 9 0,000 0,03147658 0,07572816 ! protein complex disassembly GO:0043241 17 9 0,000 0,03147658 0,07564903 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03147658 0,07557007 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03147658 0,07549127 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03147658 0,07541263 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03147658 0,07533416 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03147658 0,07525585 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03147658 0,0751777 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03147658 0,07509971 ! protein targeting to ER GO:0045047 19 9 0,000 0,03147658 0,07502189 ! T cell selection GO:0045058 18 9 0,000 0,03147658 0,07494423 ! endoderm development GO:0007492 12 9 0,000 0,03147658 0,07486673 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03147658 0,07478938 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03147658 0,0747122 ! arginine catabolic process GO:0006527 10 9 0,000 0,03147658 0,07463518 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03147658 0,07455832 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03147658 0,07448161 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03147658 0,07440506 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03147658 0,07432867 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03147658 0,07425243 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03147658 0,07417636 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03147658 0,07410043 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03147658 0,07402467 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03147658 0,07394905 ! mannose metabolic process GO:0006013 9 9 0,000 0,03147658 0,0738736 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03147658 0,07379829 ! epithelial cell development GO:0002064 10 9 0,000 0,03147658 0,07372314 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03147658 0,07364814 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03147658 0,0735733 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03147658 0,0734986 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03147658 0,07342406 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03147658 0,07334967 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03147658 0,07327543 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03147658 0,07320134 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03147658 0,0731274 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03147658 0,07305361 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03147658 0,07297996 ! DNA ligation GO:0006266 14 9 0,000 0,03147658 0,07290647 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03147658 0,07283312 ! response to amine stimulus GO:0014075 13 9 0,000 0,03147658 0,07275992 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03147658 0,07268687 ! erythrocyte development GO:0048821 11 9 0,000 0,03147658 0,07261397 ! renal water homeostasis GO:0003091 14 9 0,000 0,03147658 0,07254121 ! postreplication repair GO:0006301 11 9 0,000 0,03147658 0,07246859 ! mRNA cleavage GO:0006379 13 9 0,000 0,03147658 0,07239612 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03147658 0,0723238 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03147658 0,07225162 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03147658 0,07217959 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03147658 0,07210769 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03147658 0,07203594 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03147658 0,07196434 ! acid secretion GO:0046717 14 9 0,000 0,03147658 0,07189287 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03147658 0,07182155 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03147658 0,07175037 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03147658 0,07167933 ! purine base metabolic process GO:0006144 18 9 0,000 0,03147658 0,07160843 ! oocyte differentiation GO:0009994 12 9 0,000 0,03147658 0,07153767 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03147658 0,07146705 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03147658 0,07139657 ! spleen development GO:0048536 15 9 0,000 0,03147658 0,07132623 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03147658 0,07125603 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03147658 0,07118596 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03147658 0,07111604 ! detection of calcium ion GO:0005513 13 9 0,000 0,03147658 0,07104625 ! blastocyst formation GO:0001825 12 9 0,000 0,03147658 0,07097659 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03147658 0,07090708 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03147658 0,07083769 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03147658 0,07076845 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03147658 0,07069934 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03147658 0,07063036 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03147658 0,07056152 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03147658 0,07049282 ! prepulse inhibition GO:0060134 14 9 0,000 0,03147658 0,07042425 ! embryonic placenta development GO:0001892 12 9 0,000 0,03147658 0,07035581 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03147658 0,0702875 ! insulin secretion GO:0030073 17 9 0,000 0,03147658 0,07021932 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03147658 0,07015128 ! response to nicotine GO:0035094 16 9 0,000 0,03147658 0,07008337 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03147658 0,07001559 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03147658 0,06994795 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,03201614 0,07107831 ! regulation of lyase activity GO:0051339 133 79 1,000 0,03201614 0,07100977 ! forebrain development GO:0030900 131 80 1,000 0,03276338 0,07259708 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,03351746 0,0741965 ! mRNA transport GO:0051028 121 81 1,000 0,03351746 0,07412516 ! response to protein stimulus GO:0051789 111 81 1,000 0,03351746 0,07405396 ! ossification GO:0001503 134 82 1,000 0,03427834 0,07566237 GO:0060348|bone development, ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03491322 0,07698984 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03491322 0,07691609 ! neuron fate specification GO:0048665 11 10 0,000 0,03491322 0,07684249 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03491322 0,07676903 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03491322 0,0766957 ! thyroid gland development GO:0030878 19 10 0,000 0,03491322 0,07662252 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03491322 0,07654948 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03491322 0,07647657 ! synapsis GO:0007129 13 10 0,000 0,03491322 0,07640381 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03491322 0,07633118 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03491322 0,07625869 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03491322 0,07618634 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03491322 0,07611412 ! sulfate transport GO:0008272 12 10 0,000 0,03491322 0,07604205 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03491322 0,07597011 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03491322 0,0758983 ! androgen metabolic process GO:0008209 13 10 0,000 0,03491322 0,07582663 ! phospholipid efflux GO:0033700 16 10 0,000 0,03491322 0,0757551 ! hippocampus development GO:0021766 19 10 0,000 0,03491322 0,0756837 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03491322 0,07561243 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03491322 0,0755413 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03491322 0,0754703 ! pathogenesis GO:0009405 13 10 0,000 0,03491322 0,07539944 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03491322 0,07532871 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03491322 0,07525811 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03491322 0,07518764 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,03491322 0,07511731 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03491322 0,0750471 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03491322 0,07497703 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03491322 0,07490709 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03491322 0,07483728 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03491322 0,0747676 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03491322 0,07469805 ! response to X-ray GO:0010165 16 10 0,000 0,03491322 0,07462863 ! B cell proliferation GO:0042100 14 10 0,000 0,03491322 0,07455933 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03491322 0,07449017 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03491322 0,07442113 ! forebrain cell migration GO:0021885 17 10 0,000 0,03491322 0,07435222 ! lipid digestion GO:0044241 15 10 0,000 0,03491322 0,07428344 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03491322 0,07421479 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03491322 0,07414626 ! UV protection GO:0009650 14 10 0,000 0,03491322 0,07407786 ! entry into host cell GO:0030260 20 10 0,000 0,03491322 0,07400959 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03491322 0,07394144 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03491322 0,07387341 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03491322 0,07380552 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03491322 0,07373774 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03491322 0,07367009 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03491322 0,07360257 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03491322 0,07353517 ! regulation of organ growth GO:0046620 11 10 0,000 0,03491322 0,07346789 ! response to dsRNA GO:0043331 18 10 0,000 0,03491322 0,07340073 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03491322 0,0733337 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03491322 0,07326679 ! embryonic axis specification GO:0000578 12 10 0,000 0,03491322 0,0732 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03491322 0,07313333 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03491322 0,07306679 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03491322 0,07300036 ! cranial nerve development GO:0021545 12 10 0,000 0,03491322 0,07293406 ! fucose catabolic process GO:0019317 16 10 0,000 0,03491322 0,07286788 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03491322 0,07280181 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03491322 0,07273587 ! protein sumoylation GO:0016925 12 10 0,000 0,03491322 0,07267005 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03491322 0,07260434 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03491322 0,07253875 ! zymogen activation GO:0031638 14 10 0,000 0,03491322 0,07247329 ! salivary gland development GO:0007431 22 10 0,000 0,03491322 0,07240794 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03491322 0,0723427 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03491322 0,07227759 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03491322 0,07221259 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03491322 0,07214771 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03491322 0,07208295 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03491322 0,0720183 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03491322 0,07195376 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03491322 0,07188935 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03491322 0,07182505 ! detection of bacterium GO:0016045 10 10 0,000 0,03491322 0,07176086 ! embryonic gut development GO:0048566 11 10 0,000 0,03491322 0,07169679 ! activation of innate immune response GO:0002218 10 10 0,000 0,03491322 0,07163283 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03491322 0,07156899 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03491322 0,07150525 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03491322 0,07144164 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03491322 0,07137813 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03491322 0,07131474 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,03504596 0,07152237 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,03582026 0,07303776 ! regulation of membrane potential GO:0042391 128 85 1,000 0,03660118 0,07456397 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,03660118 0,07449798 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,03738868 0,07603357 ! rRNA transcription GO:0009303 17 11 0,000 0,03833786 0,07789495 ! respiratory burst GO:0045730 14 11 0,000 0,03833786 0,0778262 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03833786 0,07775757 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03833786 0,07768906 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03833786 0,07762067 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03833786 0,0775524 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03833786 0,07748426 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03833786 0,07741623 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03833786 0,07734832 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03833786 0,07728053 ! mating GO:0007618 14 11 0,000 0,03833786 0,07721286 ! T cell proliferation GO:0042098 20 11 0,000 0,03833786 0,0771453 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03833786 0,07707787 ! bone resorption GO:0045453 16 11 0,000 0,03833786 0,07701055 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03833786 0,07694335 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03833786 0,07687627 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03833786 0,07680931 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03833786 0,07674246 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03833786 0,07667572 ! syncytium formation GO:0006949 15 11 0,000 0,03833786 0,07660911 ! plasma membrane organization GO:0007009 18 11 0,000 0,03833786 0,07654261 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03833786 0,07647622 ! focal adhesion formation GO:0048041 24 11 0,000 0,03833786 0,07640995 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03833786 0,07634379 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03833786 0,07627775 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03833786 0,07621183 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03833786 0,07614601 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03833786 0,07608031 ! adult heart development GO:0007512 11 11 0,000 0,03833786 0,07601473 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03833786 0,07594925 ! temperature homeostasis GO:0001659 16 11 0,000 0,03833786 0,07588389 ! L-glutamate transport GO:0015813 16 11 0,000 0,03833786 0,07581864 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03833786 0,07575351 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03833786 0,07568848 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03833786 0,07562357 ! stem cell development GO:0048864 29 11 0,000 0,03833786 0,07555877 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03833786 0,07549408 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03833786 0,0754295 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03833786 0,07536503 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03833786 0,07530067 ! vasoconstriction GO:0042310 15 11 0,000 0,03833786 0,07523642 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03833786 0,07517228 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03833786 0,07510825 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03833786 0,07504433 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03833786 0,07498051 ! ribosome assembly GO:0042255 13 11 0,000 0,03833786 0,07491681 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03833786 0,07485321 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03833786 0,07478972 ! chromatin silencing GO:0006342 19 11 0,000 0,03833786 0,07472634 ! nucleosome positioning GO:0016584 13 11 0,000 0,03833786 0,07466307 ! T cell homeostasis GO:0043029 20 11 0,000 0,03833786 0,0745999 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03833786 0,07453684 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03833786 0,07447389 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03833786 0,07441104 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03833786 0,0743483 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03833786 0,07428566 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03833786 0,07422313 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03833786 0,07416071 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03833786 0,07409839 ! male genitalia development GO:0030539 13 11 0,000 0,03833786 0,07403617 ! cholesterol efflux GO:0033344 19 11 0,000 0,03833786 0,07397406 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03833786 0,07391206 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03833786 0,07385015 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03833786 0,07378835 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03833786 0,07372666 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03833786 0,07366506 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03833786 0,07360357 ! defense response to fungus GO:0050832 12 11 0,000 0,03833786 0,07354219 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03833786 0,0734809 ! lysogeny GO:0030069 18 11 0,000 0,03833786 0,07341972 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03833786 0,07335864 ! acrosome reaction GO:0007340 13 11 0,000 0,03833786 0,07329766 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03833786 0,07323678 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,03898317 0,07440771 ! establishment of RNA localization GO:0051236 128 88 1,000 0,03898317 0,07434601 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! reproductive developmental process GO:0003006 127 89 1,000 0,03979005 0,07582197 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,03979005 0,0757592 ! regulation of T cell activation GO:0050863 128 89 1,000 0,03979005 0,07569654 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,04060329 0,0771798 ! RNA localization GO:0006403 135 91 1,000 0,04142282 0,07867258 ! lactation GO:0007595 20 12 0,000 0,04175055 0,07922959 ! reproductive cellular process GO:0048610 14 12 0,000 0,04175055 0,07916427 ! tRNA modification GO:0006400 14 12 0,000 0,04175055 0,07909906 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04175055 0,07903396 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04175055 0,07896897 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04175055 0,07890408 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04175055 0,0788393 ! non-recombinational repair GO:0000726 19 12 0,000 0,04175055 0,07877462 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04175055 0,07871005 ! peroxisomal transport GO:0043574 21 12 0,000 0,04175055 0,07864559 ! cartilage condensation GO:0001502 18 12 0,000 0,04175055 0,07858123 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04175055 0,07851698 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04175055 0,07845283 ! heart looping GO:0001947 15 12 0,000 0,04175055 0,07838879 ! palate development GO:0060021 15 12 0,000 0,04175055 0,07832485 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04175055 0,07826101 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04175055 0,07819728 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04175055 0,07813366 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04175055 0,07807013 ! arginine metabolic process GO:0006525 13 12 0,000 0,04175055 0,07800671 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04175055 0,07794339 ! methionine metabolic process GO:0006555 13 12 0,000 0,04175055 0,07788018 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04175055 0,07781707 ! Golgi organization GO:0007030 18 12 0,000 0,04175055 0,07775406 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04175055 0,07769115 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04175055 0,07762834 ! monoamine transport GO:0015844 13 12 0,000 0,04175055 0,07756564 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04175055 0,07750304 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04175055 0,07744053 ! L-amino acid transport GO:0015807 20 12 0,000 0,04175055 0,07737813 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04175055 0,07731583 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04175055 0,07725363 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04175055 0,07719153 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04175055 0,07712953 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04175055 0,07706763 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04175055 0,07700582 ! cerebellum development GO:0021549 13 12 0,000 0,04175055 0,07694412 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04175055 0,07688252 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04175055 0,07682101 ! histone acetylation GO:0016573 23 12 0,000 0,04175055 0,0767596 ! histone methylation GO:0016571 15 12 0,000 0,04175055 0,07669829 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04175055 0,07663708 ! gland morphogenesis GO:0022612 23 12 0,000 0,04175055 0,07657597 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04175055 0,07651495 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,04175055 0,07645403 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04175055 0,07639321 ! response to gamma radiation GO:0010332 20 12 0,000 0,04175055 0,07633248 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04175055 0,07627185 ! intestinal absorption GO:0050892 19 12 0,000 0,04175055 0,07621132 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04175055 0,07615088 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04175055 0,07609054 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04175055 0,07603029 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04175055 0,07597014 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04175055 0,07591009 ! microspike assembly GO:0030035 23 12 0,000 0,04175055 0,07585013 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04175055 0,07579026 ! response to cold GO:0009409 14 12 0,000 0,04175055 0,07573049 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,04224861 0,07657352 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,04308059 0,07801996 ! regulation of binding GO:0051098 151 95 1,000 0,04476292 0,08100292 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,04515132 0,08164154 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04515132 0,0815774 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04515132 0,08151337 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04515132 0,08144944 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04515132 0,08138561 ! water transport GO:0006833 17 13 0,000 0,04515132 0,08132188 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04515132 0,08125824 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04515132 0,08119471 ! lipid localization GO:0010876 24 13 0,000 0,04515132 0,08113128 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04515132 0,08106794 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04515132 0,08100471 ! organelle fusion GO:0048284 28 13 0,000 0,04515132 0,08094157 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04515132 0,08087853 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04515132 0,08081559 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04515132 0,08075275 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04515132 0,08069 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04515132 0,08062736 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04515132 0,08056481 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04515132 0,08050235 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04515132 0,08044 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04515132 0,08037774 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04515132 0,08031557 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04515132 0,0802535 ! NAD metabolic process GO:0019674 21 13 0,000 0,04515132 0,08019153 ! exocrine system development GO:0035272 27 13 0,000 0,04515132 0,08012966 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04515132 0,08006788 ! bone mineralization GO:0030282 15 13 0,000 0,04515132 0,08000619 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04515132 0,0799446 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04515132 0,0798831 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04515132 0,0798217 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04515132 0,0797604 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04515132 0,07969918 ! genitalia development GO:0048806 15 13 0,000 0,04515132 0,07963806 ! regulation of cellular pH GO:0030641 20 13 0,000 0,04515132 0,07957704 ! cellular pigmentation GO:0033059 24 13 0,000 0,04515132 0,07951611 ! tissue regeneration GO:0042246 21 13 0,000 0,04515132 0,07945527 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04515132 0,07939452 ! cofactor transport GO:0051181 19 13 0,000 0,04515132 0,07933387 ! NADP metabolic process GO:0006739 18 13 0,000 0,04515132 0,07927331 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04515132 0,07921284 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04515132 0,07915247 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04515132 0,07909218 ! gas transport GO:0015669 18 13 0,000 0,04515132 0,07903199 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04515132 0,07897189 ! regulation of axon extension GO:0030516 23 13 0,000 0,04515132 0,07891188 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04515132 0,07885196 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04515132 0,07879214 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04515132 0,0787324 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04515132 0,07867275 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04515132 0,0786132 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04515132 0,07855373 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,04561316 0,07929726 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,04561316 0,07923736 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,04561316 0,07917756 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,04646939 0,08060302 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04854022 0,0841315 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,04854022 0,08406814 ! superoxide anion generation GO:0042554 18 14 0,000 0,04854022 0,08400489 ! neuron maturation GO:0042551 21 14 0,000 0,04854022 0,08394173 ! regulation of S phase GO:0033261 18 14 0,000 0,04854022 0,08387866 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04854022 0,08381569 ! myotube differentiation GO:0014902 21 14 0,000 0,04854022 0,08375281 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04854022 0,08369003 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04854022 0,08362734 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04854022 0,08356474 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04854022 0,08350224 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04854022 0,08343983 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04854022 0,08337752 ! response to cAMP GO:0051591 19 14 0,000 0,04854022 0,0833153 ! limbic system development GO:0021761 25 14 0,000 0,04854022 0,08325317 ! startle response GO:0001964 21 14 0,000 0,04854022 0,08319113 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04854022 0,08312918 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04854022 0,08306733 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,04854022 0,08300557 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04854022 0,0829439 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04854022 0,08288233 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04854022 0,08282084 ! glycine metabolic process GO:0006544 22 14 0,000 0,04854022 0,08275945 ! pituitary gland development GO:0021983 23 14 0,000 0,04854022 0,08269814 ! cellular response to starvation GO:0009267 21 14 0,000 0,04854022 0,08263693 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04854022 0,08257581 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04854022 0,08251478 ! regulation of heart rate GO:0002027 23 14 0,000 0,04854022 0,08245384 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04854022 0,08239299 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04854022 0,08233222 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04854022 0,08227155 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04854022 0,08221097 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,04854022 0,08215047 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,04854022 0,08209007 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04854022 0,08202975 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,04854022 0,08196953 ! axon cargo transport GO:0008088 27 14 0,000 0,04854022 0,08190939 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04854022 0,08184934 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04854022 0,08178937 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04854022 0,0817295 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04854022 0,08166971 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04854022 0,08161001 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04854022 0,0815504 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04854022 0,08149087 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04854022 0,08143143 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04854022 0,08137208 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04854022 0,08131282 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04854022 0,08125364 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04854022 0,08119454 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,04854022 0,08113553 ! muscle maintenance GO:0046716 19 14 0,000 0,04854022 0,08107661 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04854022 0,08101778 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04854022 0,08095902 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04854022 0,08090036 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04854022 0,08084178 ! cell killing GO:0001906 20 14 0,000 0,04854022 0,08078328 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,04854022 0,08072487 ! cilium assembly GO:0042384 20 14 0,000 0,04854022 0,08066654 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04854022 0,0806083 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,04907348 0,08143506 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05191728 0,0860921 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05191728 0,08603007 ! metencephalon development GO:0022037 19 15 0,000 0,05191728 0,08596813 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05191728 0,08590629 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05191728 0,08584453 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05191728 0,08578286 ! skin development GO:0043588 25 15 0,000 0,05191728 0,08572128 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05191728 0,08565978 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05191728 0,08559838 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05191728 0,08553706 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05191728 0,08547583 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05191728 0,08541469 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05191728 0,08535364 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05191728 0,08529267 ! adult walking behavior GO:0007628 25 15 0,000 0,05191728 0,08523179 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05191728 0,085171 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05191728 0,08511029 ! centrosome cycle GO:0007098 16 15 0,000 0,05191728 0,08504967 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05191728 0,08498914 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05191728 0,08492869 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05191728 0,08486833 ! response to osmotic stress GO:0006970 22 15 0,000 0,05191728 0,08480805 ! vesicle coating GO:0006901 25 15 0,000 0,05191728 0,08474786 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05191728 0,08468776 ! DNA integration GO:0015074 22 15 0,000 0,05191728 0,08462774 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05191728 0,0845678 ! peptide secretion GO:0002790 27 15 0,000 0,05191728 0,08450795 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05191728 0,08444819 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05191728 0,08438851 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05191728 0,08432891 ! neuron recognition GO:0008038 22 15 0,000 0,05191728 0,0842694 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05191728 0,08420997 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05191728 0,08415062 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05191728 0,08409136 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05191728 0,08403219 ! biomineral formation GO:0031214 18 15 0,000 0,05191728 0,08397309 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05191728 0,08391408 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05191728 0,08385515 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05191728 0,08379631 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05191728 0,08373754 ! organic cation transport GO:0015695 19 15 0,000 0,05191728 0,08367886 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05191728 0,08362026 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05191728 0,08356175 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,05191728 0,08350331 ! defense response to virus GO:0051607 27 15 0,000 0,05191728 0,08344496 ! peptide hormone processing GO:0016486 19 15 0,000 0,05191728 0,08338669 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05191728 0,0833285 ! protein secretion GO:0009306 27 16 0,000 0,05528254 0,08866796 ! hormone secretion GO:0046879 25 16 0,000 0,05528254 0,08860617 ! bone remodeling GO:0046849 24 16 0,000 0,05528254 0,08854446 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05528254 0,08848285 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,05528254 0,08842132 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05528254 0,08835987 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05528254 0,08829851 ! glial cell development GO:0021782 24 16 0,000 0,05528254 0,08823723 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05528254 0,08817604 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05528254 0,08811494 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,05528254 0,08805391 ! protein polyubiquitination GO:0000209 26 16 0,000 0,05528254 0,08799298 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,05528254 0,08793212 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,05528254 0,08787136 ! fructose metabolic process GO:0006000 20 16 0,000 0,05528254 0,08781067 ! regulation of protein binding GO:0043393 27 16 0,000 0,05528254 0,08775007 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05528254 0,08768955 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,05528254 0,08762912 ! protein export from nucleus GO:0006611 24 16 0,000 0,05528254 0,08756877 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05528254 0,0875085 ! DNA replication initiation GO:0006270 25 16 0,000 0,05528254 0,08744832 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05528254 0,08738821 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,05528254 0,08732819 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05528254 0,08726826 ! diencephalon development GO:0021536 25 16 0,000 0,05528254 0,0872084 ! oogenesis GO:0048477 23 16 0,000 0,05528254 0,08714863 ! neural crest cell migration GO:0001755 24 16 0,000 0,05528254 0,08708894 ! G1 phase GO:0051318 27 16 0,000 0,05528254 0,08702933 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,05528254 0,0869698 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05528254 0,08691036 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05528254 0,08685099 ! steroid catabolic process GO:0006706 22 16 0,000 0,05528254 0,08679171 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05528254 0,0867325 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05528254 0,08667338 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05528254 0,08661434 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05528254 0,08655538 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05528254 0,0864965 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,05528254 0,0864377 ! nerve development GO:0021675 18 16 0,000 0,05528254 0,08637898 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,05528254 0,08632033 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05528254 0,08626177 ! negative regulation of translation GO:0017148 22 16 0,000 0,05528254 0,08620329 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,05863606 0,09137055 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,05863606 0,09130869 ! negative regulation of defense response GO:0031348 19 17 0,000 0,05863606 0,09124691 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,05863606 0,09118522 ! glycerol metabolic process GO:0006071 20 17 0,000 0,05863606 0,0911236 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,05863606 0,09106208 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,05863606 0,09100063 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,05863606 0,09093927 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,05863606 0,09087799 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,05863606 0,09081679 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,05863606 0,09075568 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,05863606 0,09069464 ! memory GO:0007613 25 17 0,000 0,05863606 0,09063369 ! keratinization GO:0031424 17 17 0,000 0,05863606 0,09057282 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,05863606 0,09051204 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,05863606 0,09045133 ! retinoid metabolic process GO:0001523 22 17 0,000 0,05863606 0,09039071 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,05863606 0,09033016 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,05863606 0,0902697 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,05863606 0,09020932 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,05863606 0,09014902 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,05863606 0,0900888 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,05863606 0,09002866 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,05863606 0,0899686 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,05863606 0,08990862 ! membrane budding GO:0006900 29 17 0,000 0,05863606 0,08984872 ! heme metabolic process GO:0042168 27 17 0,000 0,05863606 0,0897889 ! actin filament bundle formation GO:0051017 26 17 0,000 0,05863606 0,08972916 ! body fluid secretion GO:0007589 27 17 0,000 0,05863606 0,0896695 ! stem cell differentiation GO:0048863 36 17 0,000 0,05863606 0,08960992 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,05863606 0,08955042 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,05863606 0,089491 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,05863606 0,08943165 ! sensory perception of pain GO:0019233 23 17 0,000 0,05863606 0,08937239 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,05863606 0,0893132 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,05863606 0,08925409 ! synaptogenesis GO:0007416 24 17 0,000 0,05863606 0,08919506 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,05863606 0,08913611 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,05863606 0,08907724 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,05863606 0,08901844 ! cell-cell junction organization GO:0045216 25 17 0,000 0,05863606 0,08895972 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,05863606 0,08890108 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,05863606 0,08884251 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,05863606 0,08878403 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,05863606 0,08872562 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,05863606 0,08866728 ! positive regulation of translation GO:0045727 28 18 0,000 0,06197786 0,09365905 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,06197786 0,09359756 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,06197786 0,09353614 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06197786 0,09347481 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,06197786 0,09341355 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06197786 0,09335238 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06197786 0,09329128 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06197786 0,09323027 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06197786 0,09316933 ! axis specification GO:0009798 26 18 0,000 0,06197786 0,09310848 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06197786 0,0930477 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06197786 0,092987 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,06197786 0,09292639 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06197786 0,09286585 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06197786 0,09280539 ! response to retinoic acid GO:0032526 25 18 0,000 0,06197786 0,09274501 ! pigmentation during development GO:0048066 31 18 0,000 0,06197786 0,09268471 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06197786 0,09262448 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,06197786 0,09256434 ! fucose metabolic process GO:0006004 26 18 0,000 0,06197786 0,09250427 ! response to fungus GO:0009620 19 18 0,000 0,06197786 0,09244428 ! peptide cross-linking GO:0018149 31 18 0,000 0,06197786 0,09238437 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,06197786 0,09232453 ! heart process GO:0003015 27 18 0,000 0,06197786 0,09226478 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,06197786 0,0922051 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06197786 0,09214549 ! visual learning GO:0008542 35 18 0,000 0,06197786 0,09208597 ! somitogenesis GO:0001756 24 18 0,000 0,06197786 0,09202652 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06197786 0,09196715 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,06197786 0,09190785 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06197786 0,09184863 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,06197786 0,09178949 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06197786 0,09173042 ! vitamin transport GO:0051180 24 18 0,000 0,06197786 0,09167143 ! hormone transport GO:0009914 27 18 0,000 0,06197786 0,09161252 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,06197786 0,09155368 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,06197786 0,09149492 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06197786 0,09143623 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06197786 0,09137761 ! cell-cell recognition GO:0009988 20 18 0,000 0,06197786 0,09131908 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06197786 0,09126061 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,06197786 0,09120223 ! regulation of glucose import GO:0046324 21 18 0,000 0,06197786 0,09114391 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,06197786 0,09108567 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06197786 0,09102751 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,06197786 0,09096942 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,06530799 0,09579616 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,06530799 0,0957351 ! positive regulation of ossification GO:0045778 30 19 0,000 0,06530799 0,09567412 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,06530799 0,09561322 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,06530799 0,0955524 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,06530799 0,09549166 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,06530799 0,09543099 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,06530799 0,0953704 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,06530799 0,09530988 ! regeneration GO:0031099 32 19 0,000 0,06530799 0,09524945 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,06530799 0,09518908 ! response to alkaloid GO:0043279 32 19 0,000 0,06530799 0,0951288 ! sensory perception of taste GO:0050909 23 19 0,000 0,06530799 0,09506859 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,06530799 0,09500846 ! smooth muscle contraction GO:0006939 36 19 0,000 0,06530799 0,0949484 ! peroxisome organization GO:0007031 29 19 0,000 0,06530799 0,09488842 ! digestive system process GO:0022600 30 19 0,000 0,06530799 0,09482852 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,06530799 0,09476869 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,06530799 0,09470894 ! response to vitamin A GO:0033189 26 19 0,000 0,06530799 0,09464926 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,06530799 0,09458966 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,06530799 0,09453013 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,06530799 0,09447068 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,06530799 0,0944113 ! response to starvation GO:0042594 30 19 0,000 0,06530799 0,09435199 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,06530799 0,09429277 ! plasma membrane fusion GO:0045026 23 19 0,000 0,06530799 0,09423361 ! cytolysis GO:0019835 20 19 0,000 0,06530799 0,09417453 ! renal system process GO:0003014 35 19 0,000 0,06530799 0,09411552 ! vasodilation GO:0042311 33 19 0,000 0,06530799 0,09405659 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,06530799 0,09399773 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,06530799 0,09393895 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,06530799 0,09388023 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,06530799 0,0938216 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,06530799 0,09376303 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,06530799 0,09370454 ! sarcomere organization GO:0045214 23 19 0,000 0,06530799 0,09364612 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,06530799 0,09358777 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,06530799 0,0935295 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,06530799 0,0934713 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,06530799 0,09341317 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,06530799 0,09335511 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,06530799 0,09329713 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,06530799 0,09323921 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,06530799 0,09318137 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,06862649 0,0978555 ! iron ion transport GO:0006826 37 20 0,000 0,06862649 0,09779487 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,06862649 0,09773431 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,06862649 0,09767383 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,06862649 0,09761343 ! response to vitamin GO:0033273 29 20 0,000 0,06862649 0,0975531 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,06862649 0,09749285 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,06862649 0,09743266 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,06862649 0,09737256 ! spinal cord development GO:0021510 31 20 0,000 0,06862649 0,09731253 ! response to ethanol GO:0045471 37 20 0,000 0,06862649 0,09725257 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,06862649 0,09719268 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,06862649 0,09713287 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,06862649 0,09707313 ! chromosome condensation GO:0030261 31 20 0,000 0,06862649 0,09701347 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,06862649 0,09695388 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,06862649 0,09689436 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,06862649 0,09683492 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,06862649 0,09677555 ! DNA modification GO:0006304 28 20 0,000 0,06862649 0,09671625 ! collagen fibril organization GO:0030199 45 20 0,000 0,06862649 0,09665702 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,06862649 0,09659787 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,06862649 0,09653879 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,06862649 0,09647978 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,06862649 0,09642084 ! collagen catabolic process GO:0030574 25 20 0,000 0,06862649 0,09636198 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,06862649 0,09630318 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,06862649 0,09624446 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,06862649 0,09618581 ! alditol metabolic process GO:0019400 24 20 0,000 0,06862649 0,09612723 ! actin filament-based movement GO:0030048 34 20 0,000 0,06862649 0,09606873 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,07193339 0,10063674 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,07193339 0,10057556 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,07193339 0,10051446 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,07193339 0,10045343 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,07193339 0,10039247 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07193339 0,10033159 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07193339 0,10027079 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,07193339 0,10021005 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,07193339 0,10014939 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07193339 0,10008881 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07193339 0,10002829 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07193339 0,09996785 ! protein amino acid acylation GO:0043543 37 21 0,000 0,07193339 0,09990749 ! vesicle docking GO:0048278 27 21 0,000 0,07193339 0,09984719 ! phototransduction GO:0007602 25 21 0,000 0,07193339 0,09978697 ! dendrite development GO:0016358 35 21 0,000 0,07193339 0,09972682 ! visual behavior GO:0007632 39 21 0,000 0,07193339 0,09966674 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,07193339 0,09960674 ! ovarian follicle development GO:0001541 30 21 0,000 0,07193339 0,09954681 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,07193339 0,09948695 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07193339 0,09942716 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07193339 0,09936745 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07193339 0,0993078 ! cell aging GO:0007569 32 21 0,000 0,07193339 0,09924823 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,07193339 0,09918873 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07193339 0,0991293 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07193339 0,09906994 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07193339 0,09901065 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07193339 0,09895143 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07193339 0,09889229 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,07193339 0,09883321 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07193339 0,09877421 ! fatty acid transport GO:0015908 30 21 0,000 0,07193339 0,09871527 ! immunoglobulin production GO:0002377 33 21 0,000 0,07193339 0,09865641 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,07193339 0,09859761 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,07193339 0,09853889 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07193339 0,09848024 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07193339 0,09842165 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,07193339 0,09836314 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07193339 0,09830469 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07193339 0,09824632 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07193339 0,09818801 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07193339 0,09812977 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07193339 0,0980716 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07193339 0,0980135 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07193339 0,09795547 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07193339 0,09789751 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07193339 0,09783962 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07193339 0,09778179 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,07522874 0,10220089 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,07522874 0,10214056 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,07522874 0,1020803 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,07522874 0,10202011 ! viral genome replication GO:0019079 29 22 0,000 0,07522874 0,10195999 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,07522874 0,10189994 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,07522874 0,10183997 ! leukocyte adhesion GO:0007159 38 22 0,000 0,07522874 0,10178006 ! molting cycle process GO:0022404 40 22 0,000 0,07522874 0,10172023 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,07522874 0,10166046 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,07522874 0,10160077 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,07522874 0,10154114 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,07522874 0,10148159 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,07522874 0,1014221 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,07522874 0,10136269 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,07522874 0,10130334 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,07522874 0,10124406 ! lysosome organization GO:0007040 37 22 0,000 0,07522874 0,10118486 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,07522874 0,10112572 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,07522874 0,10106665 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,07522874 0,10100765 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,07522874 0,10094872 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,07522874 0,10088986 ! membrane depolarization GO:0051899 35 22 0,000 0,07522874 0,10083106 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,07522874 0,10077234 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,07522874 0,10071368 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,07522874 0,10065509 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,07522874 0,10059657 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,07522874 0,10053812 ! blastocyst development GO:0001824 37 22 0,000 0,07522874 0,10047974 ! neural tube closure GO:0001843 33 22 0,000 0,07522874 0,10042142 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,07522874 0,10036317 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,07851258 0,10468344 ! neuron fate commitment GO:0048663 32 23 0,000 0,07851258 0,10462279 ! embryonic pattern specification GO:0009880 31 23 0,000 0,07851258 0,10456221 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,07851258 0,1045017 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,07851258 0,10444126 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,07851258 0,10438089 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,07851258 0,10432059 ! vesicle targeting GO:0006903 32 23 0,000 0,07851258 0,10426035 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,07851258 0,10420019 ! osteoblast differentiation GO:0001649 40 23 0,000 0,07851258 0,1041401 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,07851258 0,10408008 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,07851258 0,10402012 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,07851258 0,10396024 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,07851258 0,10390042 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,07851258 0,10384067 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,07851258 0,103781 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,07851258 0,10372139 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,07851258 0,10366184 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,07851258 0,10360237 ! cell fate determination GO:0001709 45 23 0,000 0,07851258 0,10354297 ! pentose metabolic process GO:0019321 31 23 0,000 0,07851258 0,10348363 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,07851258 0,10342436 ! spermatid development GO:0007286 33 23 0,000 0,07851258 0,10336516 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,07851258 0,10330603 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,07851258 0,10324696 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,07851258 0,10318796 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,07851258 0,10312903 ! telomere organization GO:0032200 32 23 0,000 0,07851258 0,10307017 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,07851258 0,10301137 ! regulation of amine transport GO:0051952 38 23 0,000 0,07851258 0,10295264 ! liver development GO:0001889 40 23 0,000 0,07851258 0,10289398 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,08178494 0,10712151 ! initiation of viral infection GO:0019059 42 24 0,000 0,08178494 0,10706054 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08178494 0,10699964 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,08178494 0,10693881 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08178494 0,10687805 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08178494 0,10681736 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08178494 0,10675674 ! sperm motility GO:0030317 27 24 0,000 0,08178494 0,10669618 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,08178494 0,1066357 ! vacuole organization GO:0007033 39 24 0,000 0,08178494 0,10657528 ! neural crest cell development GO:0014032 39 24 0,000 0,08178494 0,10651493 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,08178494 0,10645465 ! primary neural tube formation GO:0014020 35 24 0,000 0,08178494 0,10639444 ! negative regulation of cell development GO:0010721 56 24 0,000 0,08178494 0,1063343 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08178494 0,10627422 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08178494 0,10621421 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,08178494 0,10615427 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,08178494 0,1060944 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08178494 0,1060346 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,08178494 0,10597486 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,08504588 0,11013824 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,08504588 0,11007626 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,08504588 0,11001435 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,08504588 0,10995251 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,08504588 0,10989074 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,08504588 0,10982904 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,08504588 0,1097674 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,08504588 0,10970584 ! peptide transport GO:0015833 43 25 0,000 0,08504588 0,10964435 ! male gonad development GO:0008584 33 25 0,000 0,08504588 0,10958292 ! iron ion homeostasis GO:0055072 39 25 0,000 0,08504588 0,10952156 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,08504588 0,10946028 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,08504588 0,10939906 ! phospholipid transport GO:0015914 35 25 0,000 0,08504588 0,10933791 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,08504588 0,10927682 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,08504588 0,10921581 ! detection of light stimulus GO:0009583 30 25 0,000 0,08504588 0,10915486 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,08504588 0,10909398 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,08504588 0,10903317 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,08829541 0,11313618 ! translational initiation GO:0006413 43 26 0,000 0,08829541 0,11307319 ! regulation of pH GO:0006885 36 26 0,000 0,08829541 0,11301027 ! circadian rhythm GO:0007623 42 26 0,000 0,08829541 0,11294741 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,08829541 0,11288463 ! post-embryonic development GO:0009791 42 26 0,000 0,08829541 0,11282191 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,08829541 0,11275927 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,08829541 0,1126967 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,08829541 0,11263419 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,08829541 0,11257176 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,08829541 0,11250939 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,08829541 0,11244709 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,08829541 0,11238486 ! regulation of coagulation GO:0050818 39 26 0,000 0,08829541 0,1123227 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09153359 0,1163777 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09153359 0,1163134 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09153359 0,11624918 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09153359 0,11618502 ! membrane docking GO:0022406 39 27 0,000 0,09153359 0,11612094 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09153359 0,11605693 ! catechol metabolic process GO:0009712 43 27 0,000 0,09153359 0,11599298 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09153359 0,11592911 ! acute-phase response GO:0006953 42 27 0,000 0,09153359 0,11586531 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09153359 0,11580157 ! myofibril assembly GO:0030239 36 27 0,000 0,09153359 0,11573791 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09153359 0,11567432 ! response to ionizing radiation GO:0010212 47 27 0,000 0,09153359 0,1156108 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09153359 0,11554735 ! natural killer cell activation GO:0030101 35 27 0,000 0,09153359 0,11548396 ! lipid oxidation GO:0034440 38 27 0,000 0,09153359 0,11542065 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09153359 0,1153574 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09153359 0,11529423 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09153359 0,11523112 ! gene silencing GO:0016458 41 27 0,000 0,09153359 0,11516809 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,09476046 0,11916296 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,09476046 0,11909784 ! phenol metabolic process GO:0018958 44 28 0,000 0,09476046 0,1190328 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,09476046 0,11896782 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,09476046 0,11890292 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,09476046 0,11883809 ! cell junction assembly GO:0034329 56 28 0,000 0,09476046 0,11877332 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,09476046 0,11870863 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,09476046 0,11864401 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,09476046 0,11857946 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,09476046 0,11851498 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,09476046 0,11845057 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,09476046 0,11838623 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,09476046 0,11832196 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,09476046 0,11825776 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,09476046 0,11819363 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,09476046 0,11812957 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,09476046 0,11806557 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,09476046 0,11800165 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,09476046 0,1179378 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,09476046 0,11787401 ! BMP signaling pathway GO:0030509 40 28 0,000 0,09476046 0,1178103 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,09476046 0,11774665 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,09476046 0,11768307 ! neural tube formation GO:0001841 41 28 0,000 0,09476046 0,11761956 ! placenta development GO:0001890 37 28 0,000 0,09476046 0,11755612 ! regulation of B cell activation GO:0050864 42 28 0,000 0,09476046 0,11749275 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,09797604 0,12141428 ! regulation of innate immune response GO:0045088 38 29 0,000 0,09797604 0,1213489 ! ovulation cycle process GO:0022602 41 29 0,000 0,09797604 0,12128358 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,09797604 0,12121834 ! protein targeting to membrane GO:0006612 53 29 0,000 0,09797604 0,12115317 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,09797604 0,12108807 ! muscle cell development GO:0055001 38 29 0,000 0,09797604 0,12102304 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,09797604 0,12095808 ! eye morphogenesis GO:0048592 51 29 0,000 0,09797604 0,12089319 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,09797604 0,12082836 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,10118039 0,12471324 ! collagen metabolic process GO:0032963 40 30 0,000 0,10118039 0,12464644 ! organic anion transport GO:0015711 51 30 0,000 0,10118039 0,12457971 ! cholesterol transport GO:0030301 46 30 0,000 0,10118039 0,12451306 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,10118039 0,12444647 ! spliceosome assembly GO:0000245 49 30 0,000 0,10118039 0,12437996 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,10118039 0,12431352 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,10118039 0,12424714 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,10118039 0,12418084 ! ceramide metabolic process GO:0006672 43 30 0,000 0,10118039 0,12411461 ! ovulation cycle GO:0042698 43 30 0,000 0,10118039 0,12404845 ! hindbrain development GO:0030902 45 30 0,000 0,10118039 0,12398237 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,10118039 0,12391635 ! adult locomotory behavior GO:0008344 47 30 0,000 0,10118039 0,1238504 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,10118039 0,12378452 ! response to heat GO:0009408 41 30 0,000 0,10118039 0,12371871 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,10118039 0,12365298 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,10118039 0,12358731 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,10437354 0,12741993 ! negative regulation of secretion GO:0051048 49 31 0,000 0,10437354 0,12735233 ! glial cell differentiation GO:0010001 55 31 0,000 0,10437354 0,1272848 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,10437354 0,12721735 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,10437354 0,12714997 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,10437354 0,12708266 ! segmentation GO:0035282 41 31 0,000 0,10437354 0,12701542 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,10437354 0,12694825 ! metanephros development GO:0001656 58 31 0,000 0,10437354 0,12688115 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,10437354 0,12681413 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,10437354 0,12674717 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,10437354 0,12668029 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,10437354 0,12661347 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,10437354 0,12654673 ! RNA modification GO:0009451 40 31 0,000 0,10437354 0,12648005 ! regulation of muscle development GO:0048634 48 32 0,000 0,10755553 0,13026736 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,10755553 0,13019879 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,10755553 0,1301303 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,10755553 0,13006189 ! meiosis I GO:0007127 52 32 0,000 0,10755553 0,12999354 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,10755553 0,12992527 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,10755553 0,12985707 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,10755553 0,12978893 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,10755553 0,12972088 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,10755553 0,12965289 ! cytokine production GO:0001816 44 32 0,000 0,10755553 0,12958497 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,10755553 0,12951713 ! vesicle localization GO:0051648 47 32 0,000 0,10755553 0,12944935 ! RNA export from nucleus GO:0006405 44 33 0,000 0,11072639 0,13319597 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,11072639 0,13312634 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,11072639 0,13305679 ! sister chromatid segregation GO:0000819 46 33 0,000 0,11072639 0,13298731 ! ear morphogenesis GO:0042471 42 33 0,000 0,11072639 0,1329179 ! actomyosin structure organization GO:0031032 43 33 0,000 0,11072639 0,13284856 ! cell junction organization GO:0034330 63 33 0,000 0,11072639 0,1327793 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,11072639 0,13271011 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,11072639 0,13264099 ! nucleus organization GO:0006997 49 33 0,000 0,11072639 0,13257194 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,11072639 0,13250296 ! female gonad development GO:0008585 49 33 0,000 0,11072639 0,13243406 ! positive regulation of cell development GO:0010720 54 33 0,000 0,11072639 0,13236523 ! lipid homeostasis GO:0055088 55 33 0,000 0,11072639 0,13229646 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,11072639 0,13222777 ! regulation of proteolysis GO:0030162 50 33 0,000 0,11072639 0,13215916 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,11072639 0,13209061 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,11072639 0,13202213 ! cytokinesis GO:0000910 52 33 0,000 0,11072639 0,13195373 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,11072639 0,13188539 ! mRNA catabolic process GO:0006402 48 34 0,000 0,11388617 0,13557877 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,11388617 0,13550863 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,11388617 0,13543856 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,11388617 0,13536857 ! feeding behavior GO:0007631 45 34 0,000 0,11388617 0,13529865 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,11388617 0,1352288 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,11388617 0,13515902 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,11388617 0,13508932 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,11388617 0,13501968 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,11388617 0,13495012 ! neuron migration GO:0001764 46 34 0,000 0,11388617 0,13488063 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,11388617 0,13481121 ! female gamete generation GO:0007292 43 34 0,000 0,11388617 0,13474186 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,11388617 0,13467259 ! aerobic respiration GO:0009060 47 34 0,000 0,11388617 0,13460338 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,11388617 0,13453425 ! embryonic organ development GO:0048568 45 34 0,000 0,11388617 0,13446519 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,11388617 0,13439619 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,1170349 0,13804116 ! Notch signaling pathway GO:0007219 56 35 0,000 0,1170349 0,13797041 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,1170349 0,13789973 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,1170349 0,13782912 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,1170349 0,13775858 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,1170349 0,13768811 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,1170349 0,13761772 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,1170349 0,1375474 ! glycogen metabolic process GO:0005977 48 35 0,000 0,1170349 0,13747715 ! pigment metabolic process GO:0042440 61 35 0,000 0,1170349 0,13740697 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,1170349 0,13733687 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,1170349 0,13726684 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,12017262 0,14087514 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,12017262 0,14080337 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,12017262 0,14073168 ! organic ether metabolic process GO:0018904 46 36 0,000 0,12017262 0,14066006 ! neural tube development GO:0021915 50 36 0,000 0,12017262 0,14058852 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,12017262 0,14051704 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,12017262 0,14044564 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,12017262 0,14037431 ! glucan metabolic process GO:0044042 49 36 0,000 0,12017262 0,14030306 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,12329937 0,14388054 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,12329937 0,14380758 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,12329937 0,14373469 ! learning GO:0007612 67 37 0,000 0,12329937 0,14366188 ! ion transmembrane transport GO:0034220 56 37 0,000 0,12329937 0,14358914 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,12329937 0,14351647 ! regulation of protein secretion GO:0050708 51 37 0,000 0,12329937 0,14344388 ! amino acid activation GO:0043038 52 37 0,000 0,12329937 0,14337136 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,12329937 0,14329891 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,12641519 0,14684593 ! gliogenesis GO:0042063 71 38 0,000 0,12641519 0,1467718 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,12641519 0,14669775 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,12641519 0,14662377 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,12641519 0,14654987 ! phagocytosis GO:0006909 60 38 0,000 0,12641519 0,14647604 ! pigmentation GO:0043473 74 38 0,000 0,12641519 0,14640228 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,12952011 0,14992262 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,12952011 0,14984721 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,12952011 0,14977187 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,12952011 0,14969661 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,12952011 0,14962142 ! male sex differentiation GO:0046661 53 39 0,000 0,12952011 0,14954631 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,12952011 0,14947128 ! chromatin remodeling GO:0006338 68 39 0,000 0,12952011 0,14939632 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,12952011 0,14932143 ! JNK cascade GO:0007254 54 39 0,000 0,12952011 0,14924662 ! developmental growth GO:0048589 62 39 0,000 0,12952011 0,14917188 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,13261417 0,15265896 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,13261417 0,15258259 ! regulation of tube size GO:0035150 60 40 0,000 0,13261417 0,1525063 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,13261417 0,15243008 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,13261417 0,15235395 ! peptide metabolic process GO:0006518 56 40 0,000 0,13261417 0,15227788 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,13261417 0,1522019 ! inner ear development GO:0048839 57 40 0,000 0,13261417 0,15212598 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,13261417 0,15205015 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,13261417 0,15197439 ! double-strand break repair GO:0006302 67 40 0,000 0,13261417 0,1518987 ! B cell differentiation GO:0030183 62 40 0,000 0,13261417 0,1518231 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,13261417 0,15174756 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,13261417 0,1516721 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,13261417 0,15159672 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,13569742 0,15504424 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,13569742 0,15496726 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,13569742 0,15489035 ! glucose transport GO:0015758 52 41 0,000 0,13569742 0,15481352 ! striated muscle contraction GO:0006941 62 41 0,000 0,13569742 0,15473677 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,13569742 0,15466009 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,13569742 0,15458349 ! biopolymer methylation GO:0043414 62 41 0,000 0,13569742 0,15450696 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,13569742 0,15443051 ! mitochondrial transport GO:0006839 60 42 0,000 0,13876988 0,15784902 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,13876988 0,15777099 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,13876988 0,15769304 ! cellular component disassembly GO:0022411 64 42 0,000 0,13876988 0,15761517 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,13876988 0,15753737 ! hexose transport GO:0008645 54 42 0,000 0,13876988 0,15745965 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,13876988 0,15738201 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,13876988 0,15730444 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,13876988 0,15722695 ! excretion GO:0007588 63 42 0,000 0,13876988 0,15714954 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,13876988 0,1570722 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,13876988 0,15699494 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,13876988 0,15691776 ! positive regulation of binding GO:0051099 59 43 0,000 0,14183159 0,16030106 ! leukocyte migration GO:0050900 60 43 0,000 0,14183159 0,16022232 ! neuromuscular process GO:0050905 79 43 0,000 0,14183159 0,16014367 ! activation of caspase activity GO:0006919 65 43 0,000 0,14183159 0,16006509 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,14183159 0,15998659 ! tRNA processing GO:0008033 49 43 0,000 0,14183159 0,15990816 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,14183159 0,15982982 ! vesicle organization GO:0016050 79 43 0,000 0,14183159 0,15975154 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,14183159 0,15967335 ! methylation GO:0032259 64 43 0,000 0,14183159 0,15959523 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,14488259 0,16294864 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,14488259 0,16286899 ! glycolysis GO:0006096 53 44 0,000 0,14488259 0,16278943 ! regulation of ion transport GO:0043269 57 44 0,000 0,14488259 0,16270994 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,14488259 0,16263053 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,14488259 0,1625512 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,14488259 0,16247195 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,14488259 0,16239277 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,14488259 0,16231367 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,14488259 0,16223464 ! RNA catabolic process GO:0006401 64 45 0,000 0,14792292 0,1655585 ! positive regulation of defense response GO:0031349 59 45 0,000 0,14792292 0,16547798 ! regulation of translational initiation GO:0006446 64 45 0,000 0,14792292 0,16539753 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,14792292 0,16531716 ! cell recognition GO:0008037 58 45 0,000 0,14792292 0,16523687 ! cell maturation GO:0048469 60 45 0,000 0,14792292 0,16515666 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,15095262 0,16845755 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,15095262 0,16837586 ! cell redox homeostasis GO:0045454 63 46 0,000 0,15095262 0,16829424 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,15095262 0,1682127 ! regulation of ossification GO:0030278 71 46 0,000 0,15095262 0,16813124 ! histone modification GO:0016570 68 46 0,000 0,15095262 0,16804986 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,15095262 0,16796856 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,15397171 0,17124513 ! viral infectious cycle GO:0019058 71 47 0,000 0,15397171 0,17116237 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,15397171 0,17107968 ! endocrine system development GO:0035270 83 47 0,000 0,15397171 0,17099707 ! covalent chromatin modification GO:0016569 75 47 0,000 0,15397171 0,17091454 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,15397171 0,1708321 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,15397171 0,17074973 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,15397171 0,17066744 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,15397171 0,17058523 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,15397171 0,1705031 ! chloride transport GO:0006821 67 48 0,000 0,15698024 0,17375099 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,15698024 0,17366742 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,15698024 0,17358392 ! response to temperature stimulus GO:0009266 62 48 0,000 0,15698024 0,17350051 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,15698024 0,17341717 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,15698024 0,17333392 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,15698024 0,17325075 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,15698024 0,17316765 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,15698024 0,17308464 ! regulation of endocytosis GO:0030100 63 48 0,000 0,15698024 0,1730017 ! nuclear export GO:0051168 69 48 0,000 0,15698024 0,17291885 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,15698024 0,17283607 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,15997825 0,17605262 ! sensory perception of smell GO:0007608 61 49 0,000 0,15997825 0,17596842 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,15997825 0,17588431 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,15997825 0,17580027 ! RNA elongation GO:0006354 62 49 0,000 0,15997825 0,17571632 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,15997825 0,17563244 ! germ cell development GO:0007281 68 49 0,000 0,15997825 0,17554865 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,15997825 0,17546494 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,15997825 0,1753813 ! cartilage development GO:0051216 70 49 0,000 0,15997825 0,17529775 ! regulation of actin filament length GO:0030832 72 50 0,000 0,16296576 0,17848631 ! ear development GO:0043583 72 50 0,000 0,16296576 0,17840136 ! membrane fusion GO:0006944 80 50 0,000 0,16296576 0,17831649 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,16296576 0,1782317 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,16296576 0,17814698 ! proton transport GO:0015992 75 50 0,000 0,16296576 0,17806235 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,16296576 0,1779778 ! hydrogen transport GO:0006818 77 51 0,000 0,16594282 0,18114309 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,16594282 0,18105716 ! adult behavior GO:0030534 80 51 0,000 0,16594282 0,18097131 ! transition metal ion transport GO:0000041 74 52 0,000 0,16890947 0,18411932 ! regulation of cellular component size GO:0032535 74 52 0,000 0,16890947 0,1840321 ! aging GO:0007568 79 52 0,000 0,16890947 0,18394497 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,16890947 0,18385791 ! establishment of organelle localization GO:0051656 85 52 0,000 0,16890947 0,18377094 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,17186573 0,1868989 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,17186573 0,18681057 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,17186573 0,18672233 ! kidney development GO:0001822 90 53 0,000 0,17186573 0,18663417 ! single fertilization GO:0007338 59 53 0,000 0,17186573 0,18654609 ! cell projection assembly GO:0030031 76 53 0,000 0,17186573 0,1864581 ! amino acid transport GO:0006865 84 54 0,000 0,17481164 0,18956472 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,17481164 0,18947539 ! regulation of mitosis GO:0007088 84 54 0,000 0,17481164 0,18938614 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,17481164 0,18929697 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,17481164 0,18920789 ! DNA catabolic process GO:0006308 67 54 0,000 0,17481164 0,1891189 ! detection of external stimulus GO:0009581 66 54 0,000 0,17481164 0,18902998 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,17481164 0,18894115 ! exocytosis GO:0006887 74 55 0,000 0,17774724 0,19202379 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,17774724 0,19193364 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,17774724 0,19184357 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,18067257 0,19490943 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,18067257 0,19481805 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,18067257 0,19472676 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,18358766 0,19777593 ! carbohydrate transport GO:0008643 74 57 0,000 0,18358766 0,19768334 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,18358766 0,19759083 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,18358766 0,19749841 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,18358766 0,19740608 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,18358766 0,19731384 ! camera-type eye development GO:0043010 88 57 0,000 0,18358766 0,19722168 ! secondary metabolic process GO:0019748 84 57 0,000 0,18358766 0,1971296 ! developmental maturation GO:0021700 75 57 0,000 0,18358766 0,19703761 ! gonad development GO:0008406 79 57 0,000 0,18358766 0,19694571 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,18649254 0,19996869 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,18649254 0,19987551 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,18649254 0,19978241 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,18938725 0,20278895 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,18938725 0,20269459 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,18938725 0,20260031 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,19227183 0,20559052 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,19227183 0,20549498 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,19227183 0,20539954 ! regulation of heart contraction GO:0008016 91 60 0,000 0,19227183 0,20530418 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,19227183 0,20520891 ! fertilization GO:0009566 68 60 0,000 0,19227183 0,20511373 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,1951463 0,20808368 ! meiosis GO:0007126 96 61 0,000 0,1951463 0,20798726 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,1951463 0,20789092 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,1951463 0,20779468 ! urogenital system development GO:0001655 101 61 0,000 0,1951463 0,20769852 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,1951463 0,20760245 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,1951463 0,20750647 ! extracellular matrix organization GO:0030198 103 61 0,000 0,1951463 0,20741058 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,1951463 0,20731478 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,1951463 0,20721907 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,1951463 0,20712344 ! amine catabolic process GO:0009310 90 62 0,000 0,19801072 0,21006672 ! neurotransmitter transport GO:0006836 81 62 0,000 0,19801072 0,20996987 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,19801072 0,20987311 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,19801072 0,20977644 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,19801072 0,20967986 ! meiotic cell cycle GO:0051321 97 62 0,000 0,19801072 0,20958336 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,20370948 0,21551601 ! appendage morphogenesis GO:0035107 93 64 0,000 0,20370948 0,21541693 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,20370948 0,21531793 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,20370948 0,21521902 ! hexose catabolic process GO:0019320 82 64 0,000 0,20370948 0,21512021 ! reproductive structure development GO:0048608 90 65 0,000 0,20654391 0,21801331 ! regulation of caspase activity GO:0043281 97 65 0,000 0,20654391 0,2179133 ! appendage development GO:0048736 94 65 0,000 0,20654391 0,21781338 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,20654391 0,21771356 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,20654391 0,21761383 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,20654391 0,21751419 ! defense response to bacterium GO:0042742 73 65 0,000 0,20654391 0,21741464 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,20654391 0,21731518 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,20654391 0,21721582 ! activation of immune response GO:0002253 83 65 0,000 0,20654391 0,21711654 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,20936841 0,21998508 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,20936841 0,21988463 ! antigen processing and presentation GO:0019882 96 66 0,000 0,20936841 0,21978427 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,20936841 0,219684 ! regulation of immune effector process GO:0002697 101 66 0,000 0,20936841 0,21958383 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,21218301 0,22243433 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,21218301 0,222333 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,21218301 0,22223175 ! acute inflammatory response GO:0002526 92 68 0,000 0,21498776 0,22506684 ! learning or memory GO:0007611 123 68 0,000 0,21498776 0,22496444 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,21498776 0,22486214 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,21498776 0,22475993 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,21498776 0,22465781 ! rhythmic process GO:0048511 105 68 0,000 0,21498776 0,22455579 ! inorganic anion transport GO:0015698 93 68 0,000 0,21498776 0,22445386 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,21778268 0,22726868 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,21778268 0,22716561 ! response to drug GO:0042493 108 69 0,000 0,21778268 0,22706263 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,21778268 0,22695975 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,22056781 0,22975814 ! humoral immune response GO:0006959 86 70 0,000 0,22056781 0,22965413 ! eye development GO:0001654 111 70 0,000 0,22056781 0,22955021 ! amine transport GO:0015837 101 70 0,000 0,22056781 0,22944639 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,22056781 0,22934266 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,22334318 0,23212351 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,22334318 0,23201866 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,22334318 0,23191391 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,22334318 0,23180926 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,22334318 0,2317047 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,22610883 0,23446813 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,22610883 0,23436247 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,22610883 0,2342569 ! regulation of blood pressure GO:0008217 107 73 0,000 0,22886479 0,23700541 ! tube morphogenesis GO:0035239 118 73 0,000 0,22886479 0,23689875 ! mitochondrion organization GO:0007005 104 73 0,000 0,22886479 0,23679218 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,22886479 0,23668571 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,22886479 0,23657934 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,23161109 0,23931065 ! digestion GO:0007586 97 74 0,000 0,23161109 0,2392032 ! protein import into nucleus GO:0006606 118 74 0,000 0,23161109 0,23909583 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,23161109 0,23898857 ! blood coagulation GO:0007596 116 75 0,000 0,23434777 0,24170398 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,23434777 0,24159564 ! regulation of ligase activity GO:0051340 114 75 0,000 0,23434777 0,2414874 ! nuclear import GO:0051170 121 75 0,000 0,23434777 0,24137926 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,23434777 0,24127121 ! amine biosynthetic process GO:0009309 97 76 0,000 0,23707486 0,24396966 ! tRNA metabolic process GO:0006399 95 76 0,000 0,23707486 0,24386055 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,23979239 0,2465456 ! sex differentiation GO:0007548 105 77 0,000 0,23979239 0,24643544 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,23979239 0,24632537 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,23979239 0,24621541 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,23979239 0,24610554 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,2425004 0,24877383 ! cellular respiration GO:0045333 107 79 0,000 0,24519892 0,25143001 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,24519892 0,25131796 ! T cell activation GO:0042110 134 79 0,000 0,24519892 0,25120602 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,24519892 0,25109417 ! chromatin assembly GO:0031497 102 80 0,000 0,24788798 0,25373491 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,24788798 0,25362204 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,24788798 0,25350927 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,24788798 0,2533966 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,24788798 0,25328403 ! hemostasis GO:0007599 125 81 0,000 0,25056761 0,2559083 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,25056761 0,25579472 ! regulation of neurological system process GO:0031644 122 81 0,000 0,25056761 0,25568123 ! vitamin metabolic process GO:0006766 103 81 0,000 0,25056761 0,25556785 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,25056761 0,25545456 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,25323784 0,25806249 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,25589872 0,26065857 ! regulation of defense response GO:0031347 117 84 0,000 0,25855027 0,26324286 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,25855027 0,26312638 ! sterol metabolic process GO:0016125 120 84 0,000 0,25855027 0,26301 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,26119252 0,26558037 ! rRNA metabolic process GO:0016072 107 85 0,000 0,26119252 0,26546301 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,26119252 0,26534576 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,26119252 0,26522861 ! nucleosome organization GO:0034728 114 87 0,000 0,26644926 0,27044718 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,26644926 0,27032788 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,26644926 0,27020869 ! female pregnancy GO:0007565 130 87 0,000 0,26644926 0,2700896 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,26906381 0,27261972 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,26906381 0,27249968 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,26906381 0,27237974 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,2716692 0,27489624 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,2716692 0,27477535 ! leukocyte differentiation GO:0002521 143 90 0,000 0,27426544 0,27727935 ! hormone metabolic process GO:0042445 121 90 0,000 0,27426544 0,27715752 ! ATP metabolic process GO:0046034 137 91 0,000 0,27685258 0,27964907 ! response to virus GO:0009615 122 91 0,000 0,27685258 0,27952631 ! positive regulation of immune response GO:0050778 121 92 0,000 0,27943065 0,28200548 ! DNA recombination GO:0006310 146 92 0,000 0,27943065 0,28188179 ! sulfur metabolic process GO:0006790 118 92 0,000 0,27943065 0,28175822 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,28199967 0,28422403 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,28199967 0,28409954 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,28199967 0,28397515 ! electron transport chain GO:0022900 123 94 0,000 0,28455968 0,28642769 ! response to oxidative stress GO:0006979 141 94 0,000 0,28455968 0,28630239 ! carboxylic acid transport GO:0046942 147 95 0,000 0,28711071 0,28874274 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,28965279 0,29117195 ! protein maturation GO:0051604 129 96 0,000 0,28965279 0,29104474 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,29218595 0,29346187 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,29722564 0,29839326 ! protein import GO:0017038 156 99 0,000 0,29722564 0,29826307 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,29722564 0,298133 ! regulation of translation GO:0006417 151 100 0,000 0,29973223 0,30051618 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,29973223 0,30038524 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,29973223 0,30025441 ! divalent metal ion transport GO:0070838 171 100 0,000 0,29973223 0,30012369 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,29973223 0,29999309 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,29973223 0,2998626 ! protein localization in organelle GO:0033365 161 100 0,000 0,29973223 0,29973223