pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6574-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 4,000 5,303E-11 1,276E-07 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 3,719E-10 4,474E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,113E-09 8,928E-07 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 4,000 1,281E-09 7,704E-07 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 2,592E-09 1,247E-06 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 5,171E-09 2,074E-06 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 1,544E-08 5,308E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 1,93E-08 5,806E-06 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 2,421E-08 6,473E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of protein stability GO:0031647 73 37 4,000 8,608E-08 2,071E-05 ! endothelial cell migration GO:0043542 28 17 3,000 1,722E-07 3,767E-05 ! inositol metabolic process GO:0006020 28 17 3,000 1,722E-07 3,453E-05 ! cardiac muscle tissue development GO:0048738 31 17 3,000 1,722E-07 3,188E-05 ! myoblast cell fate commitment GO:0048625 16 6 2,000 5,128E-07 8,812E-05 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 5,234E-07 8,395E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 6,321E-07 9,506E-05 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell migration GO:0030335 126 57 4,000 7,889E-07 1,116E-04 ! lipid modification GO:0030258 97 57 4,000 7,889E-07 1,054E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 8,989E-07 1,138E-04 ! fat cell differentiation GO:0045444 50 27 3,000 1,241E-06 1,493E-04 ! positive regulation of cell motion GO:0051272 146 64 4,000 1,413E-06 1,619E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 1,43E-06 1,563E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 1,43E-06 1,495E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,43E-06 1,433E-04 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 1,925E-06 1,853E-04 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 2,545E-06 2,355E-04 ! negative regulation of protein transport GO:0051224 69 33 3,000 2,855E-06 2,544E-04 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 3,637E-06 3,125E-04 ! maintenance of protein location in cell GO:0032507 86 36 3,000 4,082E-06 3,387E-04 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 4,185E-06 3,356E-04 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 4,847E-06 3,762E-04 ! carbohydrate homeostasis GO:0033500 53 38 3,000 5,092E-06 3,828E-04 GO:0042593|glucose homeostasis, ! regulation of hormone metabolic process GO:0032350 26 12 2,000 5,568E-06 4,059E-04 ! maintenance of protein location GO:0045185 91 40 3,000 6,276E-06 4,441E-04 ! polyol metabolic process GO:0019751 66 41 3,000 6,938E-06 4,769E-04 ! cytoplasmic sequestering of protein GO:0051220 24 13 2,000 7,222E-06 4,827E-04 ! regulation of cell adhesion GO:0030155 212 89 4,000 7,254E-06 4,717E-04 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 7,651E-06 4,844E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 8,417E-06 5,192E-04 ! maintenance of location in cell GO:0051651 97 44 3,000 9,237E-06 5,556E-04 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,105E-05 6,486E-04 ! negative regulation of cell migration GO:0030336 115 46 3,000 1,105E-05 6,332E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,144E-05 6,401E-04 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 1,405E-05 7,683E-04 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 2,000 1,405E-05 7,512E-04 ! myoblast differentiation GO:0045445 45 17 2,000 1,702E-05 8,904E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,702E-05 8,715E-04 ! negative regulation of cell motion GO:0051271 134 55 3,000 2,263E-05 1,134E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 2,415E-05 1,186E-03 ! skeletal muscle fiber development GO:0048741 111 56 3,000 2,432E-05 1,17E-03 ! muscle fiber development GO:0048747 112 57 3,000 2,609E-05 1,231E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 2,609E-05 1,207E-03 ! maintenance of location GO:0051235 118 57 3,000 2,609E-05 1,185E-03 ! pancreas development GO:0031016 35 20 2,000 2,835E-05 1,263E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,835E-05 1,24E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,199E-05 1,375E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 3,301E-05 1,393E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 5,659E-05 2,348E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 6,383E-05 2,603E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 6,383E-05 2,56E-03 ! regulation of catabolic process GO:0009894 161 76 3,000 8,116E-05 3,201E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 8,78E-05 3,407E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 8,78E-05 3,353E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 8,78E-05 3,301E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 8,78E-05 3,25E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 8,78E-05 3,201E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 8,913E-05 3,201E-03 ! negative regulation of transport GO:0051051 153 84 3,000 1,199E-04 4,241E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,202E-04 4,192E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,202E-04 4,132E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 1,314E-04 4,454E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! male sex determination GO:0030238 15 6 1,000 1,314E-04 4,392E-03 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 1,314E-04 4,332E-03 ! cell fate specification GO:0001708 52 33 2,000 1,319E-04 4,29E-03 ! regulation of protein transport GO:0051223 154 87 3,000 1,373E-04 4,406E-03 GO:0070201|regulation of establishment of protein localization, ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,716E-04 5,431E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,777E-04 5,552E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,837E-04 5,665E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,837E-04 5,593E-03 GO:0043489|RNA stabilization, ! regulation of respiratory burst GO:0060263 11 7 1,000 1,837E-04 5,524E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,863E-04 5,533E-03 ! regulation of protein localization GO:0032880 176 97 3,000 2,09E-04 6,131E-03 ! skeletal muscle tissue development GO:0007519 186 99 3,000 2,26E-04 6,551E-03 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 3,000 2,349E-04 6,728E-03 ! regulation of hormone secretion GO:0046883 62 40 2,000 2,353E-04 6,662E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 2,353E-04 6,584E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,444E-04 6,759E-03 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 1,000 2,444E-04 6,682E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,444E-04 6,607E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,444E-04 6,534E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,444E-04 6,462E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,444E-04 6,392E-03 ! hormone-mediated signaling GO:0009755 74 41 2,000 2,534E-04 6,555E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,136E-04 8,027E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,136E-04 7,943E-03 ! DNA synthesis during DNA repair GO:0000731 14 9 1,000 3,136E-04 7,86E-03 ! cell proliferation in forebrain GO:0021846 15 9 1,000 3,136E-04 7,779E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 3,136E-04 7,7E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,136E-04 7,622E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 3,136E-04 7,546E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,136E-04 7,471E-03 ! receptor clustering GO:0043113 18 9 1,000 3,136E-04 7,398E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,136E-04 7,326E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,136E-04 7,255E-03 ! induction of an organ GO:0001759 14 9 1,000 3,136E-04 7,186E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 3,569E-04 8,102E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 3,569E-04 8,026E-03 ! lung alveolus development GO:0048286 26 10 1,000 3,913E-04 8,716E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 3,913E-04 8,636E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 3,913E-04 8,558E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 3,913E-04 8,481E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 3,913E-04 8,405E-03 ! localization within membrane GO:0051668 20 10 1,000 3,913E-04 8,331E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 4,049E-04 8,546E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 4,773E-04 9,985E-03 ! blood vessel remodeling GO:0001974 29 11 1,000 4,773E-04 9,899E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 4,773E-04 9,815E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 4,773E-04 9,732E-03 ! developmental induction GO:0031128 19 11 1,000 4,773E-04 9,65E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 4,773E-04 9,569E-03 ! nucleus localization GO:0051647 19 11 1,000 4,773E-04 9,49E-03 ! synapse organization GO:0050808 85 52 2,000 5,13E-04 0,01011636 ! response to UV GO:0009411 104 53 2,000 5,426E-04 0,01061325 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 5,716E-04 0,01109126 ! virus-host interaction GO:0019048 29 12 1,000 5,716E-04 0,01100253 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 5,716E-04 0,01091521 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 5,716E-04 0,01082927 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 5,716E-04 0,01074466 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 5,716E-04 0,01066137 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 5,716E-04 0,01057936 ! regulation of protein catabolic process GO:0042176 116 55 2,000 6,05E-04 0,01111201 ! nucleotide-excision repair GO:0006289 83 56 2,000 6,379E-04 0,01162695 ! regulation of DNA replication GO:0006275 101 56 2,000 6,379E-04 0,01153953 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 6,742E-04 0,01210608 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 6,742E-04 0,01201641 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 6,742E-04 0,01192805 ! regulation of mRNA stability GO:0043488 31 13 1,000 6,742E-04 0,01184099 ! positive regulation of secretion GO:0051047 95 59 2,000 7,433E-04 0,01295876 ! regulation of mRNA processing GO:0050684 24 14 1,000 7,851E-04 0,01358925 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 7,851E-04 0,01349219 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 7,851E-04 0,0133965 ! regulation of RNA stability GO:0043487 32 14 1,000 7,851E-04 0,01330216 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 8,193E-04 0,01378521 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 9,001E-04 0,01503991 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 9,041E-04 0,01500188 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,031E-03 0,0169945 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,031E-03 0,01687889 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,031E-03 0,01676484 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,031E-03 0,01665233 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! lung development GO:0030324 144 67 2,000 1,077E-03 0,01726818 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 1,124E-03 0,01790695 ! signal complex assembly GO:0007172 41 17 1,000 1,166E-03 0,01846422 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,166E-03 0,01834354 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,166E-03 0,01822443 ! respiratory tube development GO:0030323 150 70 2,000 1,222E-03 0,01897257 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,31E-03 0,02020033 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,31E-03 0,02007166 ! respiratory system development GO:0060541 153 72 2,000 1,326E-03 0,02019133 ! axon guidance GO:0007411 139 73 2,000 1,38E-03 0,02087928 ! lipid phosphorylation GO:0046834 35 19 1,000 1,461E-03 0,02196968 ! cerebral cortex development GO:0021987 36 19 1,000 1,461E-03 0,02183323 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,461E-03 0,02169845 GO:0030968|endoplasmic reticulum unfolded protein response, ! neuromuscular junction development GO:0007528 34 19 1,000 1,461E-03 0,02156533 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,461E-03 0,02143384 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 1,492E-03 0,02175018 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,62E-03 0,02348278 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,62E-03 0,02334216 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,62E-03 0,02320322 GO:0010675|regulation of cellular carbohydrate metabolic process, ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,62E-03 0,02306593 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 1,732E-03 0,02451094 ! positive regulation of locomotion GO:0040017 39 21 1,000 1,787E-03 0,02514685 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! muscle cell differentiation GO:0042692 159 80 2,000 1,795E-03 0,02511577 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 1,861E-03 0,02587534 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 1,962E-03 0,02713188 ! regulation of chemotaxis GO:0050920 40 22 1,000 1,962E-03 0,02697684 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,962E-03 0,02682356 ! protein stabilization GO:0050821 39 22 1,000 1,962E-03 0,02667202 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,145E-03 0,02899176 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,145E-03 0,02882979 ! sex determination GO:0007530 47 23 1,000 2,145E-03 0,02866963 ! negative regulation of catabolic process GO:0009895 50 23 1,000 2,145E-03 0,02851123 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,335E-03 0,03087229 ! regulation of behavior GO:0050795 43 24 1,000 2,335E-03 0,03070358 ! pallium development GO:0021543 49 24 1,000 2,335E-03 0,03053672 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,335E-03 0,03037165 ! protein tetramerization GO:0051262 52 24 1,000 2,335E-03 0,03020837 ! myelination GO:0042552 45 25 1,000 2,533E-03 0,03259628 ! vasculogenesis GO:0001570 46 25 1,000 2,533E-03 0,03242289 ! receptor metabolic process GO:0043112 46 25 1,000 2,533E-03 0,03225134 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,533E-03 0,0320816 ! interaction with host GO:0051701 62 25 1,000 2,533E-03 0,03191363 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 2,739E-03 0,03432637 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,739E-03 0,03414851 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 2,929E-03 0,03632538 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 2,953E-03 0,0364314 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,953E-03 0,03624553 ! base-excision repair GO:0006284 41 27 1,000 2,953E-03 0,03606154 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,953E-03 0,03587941 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 3,107E-03 0,03756023 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,174E-03 0,03817886 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,174E-03 0,03798892 ! interphase GO:0051325 213 98 2,000 3,198E-03 0,03808915 ! tissue homeostasis GO:0001894 48 29 1,000 3,402E-03 0,04032266 GO:0048871|multicellular organismal homeostasis, ! ensheathment of neurons GO:0007272 57 30 1,000 3,638E-03 0,04290782 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 3,638E-03 0,04269851 ! mesoderm formation GO:0001707 69 31 1,000 3,881E-03 0,04533373 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 3,881E-03 0,04511473 GO:0043433|negative regulation of transcription factor activity, ! spindle organization GO:0007051 46 32 1,000 4,132E-03 0,04779832 ! peripheral nervous system development GO:0007422 64 32 1,000 4,132E-03 0,04756962 ! formation of primary germ layer GO:0001704 72 33 1,000 4,39E-03 0,05029996 ! mesoderm morphogenesis GO:0048332 76 34 1,000 4,656E-03 0,05308751 ! mismatch repair GO:0006298 46 34 1,000 4,656E-03 0,0528371 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 4,656E-03 0,05258904 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 4,928E-03 0,05540823 ! odontogenesis GO:0042476 66 35 1,000 4,928E-03 0,05515052 ! telencephalon development GO:0021537 68 35 1,000 4,928E-03 0,05489519 ! calcium-mediated signaling GO:0019722 62 35 1,000 4,928E-03 0,05464222 ! regulation of microtubule-based process GO:0032886 78 35 1,000 4,928E-03 0,05439157 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 5,208E-03 0,05721723 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell activation GO:0050866 65 36 1,000 5,208E-03 0,05695715 ! tissue remodeling GO:0048771 76 37 1,000 5,495E-03 0,05982351 ! negative regulation of DNA binding GO:0043392 68 37 1,000 5,495E-03 0,05955403 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 5,789E-03 0,06245973 ! mammary gland development GO:0030879 86 39 1,000 6,09E-03 0,06541535 ! regulation of action potential in neuron GO:0019228 73 39 1,000 6,09E-03 0,06512462 ! negative regulation of binding GO:0051100 72 40 1,000 6,398E-03 0,06811703 ! regulation of T cell proliferation GO:0042129 71 41 1,000 6,713E-03 0,07115703 ! regulation of T cell differentiation GO:0045580 70 41 1,000 6,713E-03 0,07084494 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 7,364E-03 0,07737545 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 7,364E-03 0,07703904 ! cell growth GO:0016049 84 45 1,000 8,043E-03 0,08377144 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 8,392E-03 0,08703348 ! positive regulation of protein transport GO:0051222 72 46 1,000 8,392E-03 0,08665995 ! response to calcium ion GO:0051592 81 47 1,000 8,748E-03 0,08995084 ! endosome transport GO:0016197 108 47 1,000 8,748E-03 0,08956807 ! vascular process in circulatory system GO:0003018 80 47 1,000 8,748E-03 0,08918854 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 9,111E-03 0,09249489 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 9,111E-03 0,09210625 ! regulation of action potential GO:0001508 95 49 1,000 9,48E-03 0,09543951 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 9,48E-03 0,09504184 ! negative regulation of immune system process GO:0002683 95 50 1,000 9,856E-03 0,09840106 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,010239 0,10179764 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,010239 0,10137872 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01062804 0,10479944 ! positive regulation of growth GO:0045927 90 52 1,000 0,01062804 0,10437168 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01142548 0,11174679 GO:0010863|positive regulation of phospholipase C activity, ! gastrulation GO:0007369 112 55 1,000 0,0118338 0,11527177 ! heart morphogenesis GO:0003007 97 55 1,000 0,0118338 0,11480696 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,0118338 0,11434589 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01266943 0,12193061 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01266943 0,12144483 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01309666 0,12504194 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01309666 0,1245477 ! mesoderm development GO:0007498 119 61 1,000 0,01441553 0,13655022 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01485367 0,14014877 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01485367 0,13960131 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01485367 0,13905811 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01485367 0,13851913 ! neuron fate determination GO:0048664 7 5 0,000 0,01485367 0,13798431 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01485367 0,1374536 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01485367 0,13692696 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01485367 0,13640433 ! polyol transport GO:0015791 12 5 0,000 0,01485367 0,13588569 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01485367 0,13537097 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01485367 0,13486013 ! response to superoxide GO:0000303 10 5 0,000 0,01485367 0,13435314 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01485367 0,13384994 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01485367 0,1333505 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01485367 0,13285478 ! female meiosis GO:0007143 7 5 0,000 0,01485367 0,13236272 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01485367 0,1318743 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01485367 0,13138947 ! cobalt ion transport GO:0006824 11 5 0,000 0,01485367 0,13090819 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01485367 0,13043042 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01485367 0,12995613 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01485367 0,12948527 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01485367 0,12901782 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01485367 0,12855372 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01485367 0,12809296 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01485367 0,12763548 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01485367 0,12718126 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01485367 0,12673027 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01485367 0,12628246 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01485367 0,1258378 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01485367 0,12539626 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01485367 0,12495782 ! negative chemotaxis GO:0050919 14 5 0,000 0,01485367 0,12452242 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01485367 0,12409005 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01485367 0,12366068 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01485367 0,12323426 ! behavioral response to pain GO:0048266 9 5 0,000 0,01485367 0,12281077 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01485367 0,12239019 ! Notch receptor processing GO:0007220 8 5 0,000 0,01485367 0,12197248 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01485367 0,1215576 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01485367 0,12114554 ! micturition GO:0060073 9 5 0,000 0,01485367 0,12073627 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01485367 0,12032975 ! copulation GO:0007620 9 5 0,000 0,01485367 0,11992596 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01485367 0,11952487 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01485367 0,11912645 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01485367 0,11873068 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01485367 0,11833753 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01485367 0,11794698 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01485367 0,117559 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01485367 0,11717356 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01485367 0,11679064 ! grooming behavior GO:0007625 6 5 0,000 0,01485367 0,11641021 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01485367 0,11603226 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01485367 0,11565675 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01485367 0,11528366 ! response to protozoan GO:0001562 10 5 0,000 0,01485367 0,11491298 ! lymph vessel development GO:0001945 10 5 0,000 0,01485367 0,11454466 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01485367 0,11417871 ! endochondral ossification GO:0001958 16 5 0,000 0,01485367 0,11381508 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01485367 0,11345376 ! parathyroid gland development GO:0060017 13 5 0,000 0,01485367 0,11309473 ! anagen GO:0042640 6 5 0,000 0,01485367 0,11273797 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01485367 0,11238344 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01485367 0,11203115 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01485367 0,11168105 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01485367 0,11133313 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01485367 0,11098738 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01485367 0,11064376 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01485367 0,11030227 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01485367 0,10996288 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01485367 0,10962557 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01485367 0,10929032 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01485367 0,10895712 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01485367 0,10862594 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01485367 0,10829677 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01485367 0,10796959 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01485367 0,10764438 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01485367 0,10732113 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01485367 0,10699981 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01485367 0,1066804 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01485367 0,1063629 ! histidine catabolic process GO:0006548 6 5 0,000 0,01485367 0,10604729 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01485367 0,10573354 ! microvillus organization GO:0032528 7 5 0,000 0,01485367 0,10542164 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01485367 0,10511157 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01485367 0,10480333 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01485367 0,10449689 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01485367 0,10419223 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01485367 0,10388935 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01485367 0,10358822 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01485367 0,10328883 ! polyol catabolic process GO:0046174 7 5 0,000 0,01485367 0,10299117 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01485367 0,10269522 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01485367 0,10240096 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01485367 0,10210839 ! muscle cell migration GO:0014812 8 5 0,000 0,01485367 0,10181748 ! mitochondrial fission GO:0000266 8 5 0,000 0,01485367 0,10152823 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01485367 0,10124061 ! mRNA transcription GO:0009299 9 5 0,000 0,01485367 0,10095462 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01485367 0,10067024 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01485367 0,10038746 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01485367 0,10010626 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01485367 0,09982663 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01485367 0,09954857 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01485367 0,09927204 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01485367 0,09899705 ! response to food GO:0032094 6 5 0,000 0,01485367 0,09872358 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01485367 0,09845161 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01485367 0,09818114 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01485367 0,09791215 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01485367 0,09764463 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01485367 0,09737857 ! forebrain neuron development GO:0021884 13 5 0,000 0,01485367 0,09711395 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01485367 0,09685077 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01485367 0,09658901 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01485367 0,09632867 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01485367 0,09606972 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01485367 0,09581216 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01485367 0,09555598 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01485367 0,09530116 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01485367 0,0950477 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01485367 0,09479558 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01485367 0,0945448 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01485367 0,09429534 ! basic amino acid transport GO:0015802 11 5 0,000 0,01485367 0,0940472 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01485367 0,09380036 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01485367 0,0935548 ! depyrimidination GO:0045008 10 5 0,000 0,01485367 0,09331054 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01485367 0,09306754 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01485367 0,09282581 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01485367 0,09258532 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01485367 0,09234609 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01485367 0,09210808 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01485367 0,0918713 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01485367 0,09163573 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01485367 0,09140137 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01485367 0,0911682 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01485367 0,09093622 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01485367 0,09070542 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01485367 0,09047579 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01485367 0,09024731 ! response to arsenic GO:0046685 10 5 0,000 0,01485367 0,09001999 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01485367 0,08979381 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01485367 0,08956876 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01485367 0,08934484 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01485367 0,08912203 ! response to cadmium ion GO:0046686 7 5 0,000 0,01485367 0,08890034 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01485367 0,08867974 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01485367 0,08846024 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01485367 0,08824182 ! decidualization GO:0046697 11 5 0,000 0,01485367 0,08802447 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01485367 0,08780819 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01485367 0,08759298 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01485367 0,08737881 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01485367 0,0871657 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01485367 0,08695361 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01485367 0,08674256 ! neural tube patterning GO:0021532 7 5 0,000 0,01485367 0,08653253 ! embryonic cleavage GO:0040016 6 5 0,000 0,01485367 0,08632352 ! peroxisome fission GO:0016559 5 5 0,000 0,01485367 0,08611551 ! histone demethylation GO:0016577 10 5 0,000 0,01485367 0,0859085 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01485367 0,08570248 ! mitotic recombination GO:0006312 9 5 0,000 0,01485367 0,08549745 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01485367 0,0852934 ! metaphase plate congression GO:0051310 7 5 0,000 0,01485367 0,08509032 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01485367 0,08488821 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01485367 0,08468705 ! enteric nervous system development GO:0048484 8 5 0,000 0,01485367 0,08448684 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01485367 0,08428758 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01485367 0,08408926 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01485367 0,08389187 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01485367 0,0836954 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01485367 0,08349985 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01485367 0,08330521 ! plasminogen activation GO:0031639 5 5 0,000 0,01485367 0,08311148 ! B cell homeostasis GO:0001782 13 5 0,000 0,01485367 0,08291864 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01485367 0,0827267 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01485367 0,08253565 ! metaphase GO:0051323 8 5 0,000 0,01485367 0,08234547 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01485367 0,08215617 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01485367 0,08196774 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01485367 0,08178017 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01485367 0,08159346 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01485367 0,0814076 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01485367 0,08122258 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01485367 0,0810384 ! response to redox state GO:0051775 5 5 0,000 0,01485367 0,08085506 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01485367 0,08067254 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01485367 0,08049085 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01485367 0,08030997 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01485367 0,0801299 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01485367 0,07995064 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01485367 0,07977218 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01485367 0,07959451 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01485367 0,07941763 ! striatum development GO:0021756 9 5 0,000 0,01485367 0,07924154 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01485367 0,07906623 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01485367 0,07889169 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01485367 0,07871792 ! glial cell migration GO:0008347 11 5 0,000 0,01485367 0,07854491 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01485367 0,07837267 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01485367 0,07820117 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01485367 0,07803043 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01485367 0,07786043 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01485367 0,07769116 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01485367 0,07752264 ! neuroprotection GO:0043526 6 5 0,000 0,01485367 0,07735484 ! neural plate development GO:0001840 8 5 0,000 0,01485367 0,07718777 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01485367 0,07702141 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01485367 0,07685577 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01485367 0,07669085 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01485367 0,07652663 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01485367 0,07636311 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01485367 0,07620029 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01485367 0,07603816 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01485367 0,07587672 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01485367 0,07571596 ! spindle assembly GO:0051225 6 5 0,000 0,01485367 0,07555589 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01485367 0,07539649 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01485367 0,07523776 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01485367 0,0750797 ! drug metabolic process GO:0017144 6 5 0,000 0,01485367 0,0749223 ! stem cell division GO:0017145 11 5 0,000 0,01485367 0,07476555 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01485367 0,07460947 ! organ regeneration GO:0031100 7 5 0,000 0,01485367 0,07445403 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01485367 0,07429924 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01485367 0,07414509 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01485367 0,07399158 ! viral reproductive process GO:0022415 126 62 1,000 0,01486741 0,07390698 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01486741 0,07375459 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01673516 0,08284939 ! actin filament organization GO:0007015 148 66 1,000 0,01673516 0,08267927 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01721697 0,08488529 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01721697 0,0847117 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01721697 0,08453882 ! adaptive immune response GO:0002250 119 67 1,000 0,01721697 0,08436664 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 0,01770464 0,08657999 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01770464 0,08640437 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01779812 0,08668476 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01779812 0,08650964 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01779812 0,08633523 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01779812 0,08616152 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01779812 0,0859885 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01779812 0,08581618 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01779812 0,08564455 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01779812 0,0854736 ! sleep GO:0030431 13 6 0,000 0,01779812 0,08530333 ! response to oxygen radical GO:0000305 11 6 0,000 0,01779812 0,08513374 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01779812 0,08496483 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01779812 0,08479658 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01779812 0,084629 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01779812 0,08446208 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01779812 0,08429581 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01779812 0,0841302 ! forebrain regionalization GO:0021871 8 6 0,000 0,01779812 0,08396524 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01779812 0,08380093 ! male meiosis GO:0007140 7 6 0,000 0,01779812 0,08363725 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01779812 0,08347422 ! response to zinc ion GO:0010043 9 6 0,000 0,01779812 0,08331182 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01779812 0,08315005 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01779812 0,0829889 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01779812 0,08282838 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01779812 0,08266848 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01779812 0,0825092 ! malate metabolic process GO:0006108 11 6 0,000 0,01779812 0,08235053 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01779812 0,08219246 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01779812 0,08203501 ! protein refolding GO:0042026 15 6 0,000 0,01779812 0,08187815 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01779812 0,0817219 ! opsonization GO:0008228 8 6 0,000 0,01779812 0,08156623 ! mating behavior GO:0007617 7 6 0,000 0,01779812 0,08141117 ! neuron remodeling GO:0016322 15 6 0,000 0,01779812 0,08125669 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01779812 0,08110279 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01779812 0,08094948 ! equilibrioception GO:0050957 14 6 0,000 0,01779812 0,08079674 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01779812 0,08064458 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01779812 0,08049299 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01779812 0,08034198 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01779812 0,08019152 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01779812 0,08004163 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01779812 0,0798923 ! toxin metabolic process GO:0009404 11 6 0,000 0,01779812 0,07974353 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01779812 0,0795953 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01779812 0,07944763 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01779812 0,07930051 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01779812 0,07915392 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01779812 0,07900788 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01779812 0,07886238 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01779812 0,07871741 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01779812 0,07857298 ! thymic T cell selection GO:0045061 12 6 0,000 0,01779812 0,07842907 ! protein lipoylation GO:0009249 10 6 0,000 0,01779812 0,07828569 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01779812 0,07814283 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01779812 0,0780005 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01779812 0,07785868 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01779812 0,07771737 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01779812 0,07757658 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,01779812 0,0774363 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01779812 0,07729652 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01779812 0,07715725 ! hyperosmotic response GO:0006972 9 6 0,000 0,01779812 0,07701848 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01779812 0,0768802 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01779812 0,07674243 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01779812 0,07660514 ! urea metabolic process GO:0019627 7 6 0,000 0,01779812 0,07646835 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01779812 0,07633204 ! neutrophil activation GO:0042119 8 6 0,000 0,01779812 0,07619622 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01779812 0,07606088 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01779812 0,07592602 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01779812 0,07579163 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01779812 0,07565773 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01779812 0,07552429 ! neuron apoptosis GO:0051402 9 6 0,000 0,01779812 0,07539133 ! nucleoside salvage GO:0043174 9 6 0,000 0,01779812 0,07525883 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01779812 0,0751268 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01779812 0,07499522 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01779812 0,07486411 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01779812 0,07473346 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01779812 0,07460326 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01779812 0,07447352 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01779812 0,07434422 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01779812 0,07421538 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01779812 0,07408698 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01779812 0,07395902 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01779812 0,07383151 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01779812 0,07370443 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01779812 0,07357779 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01779812 0,07345158 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01779812 0,07332581 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01779812 0,07320047 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01779812 0,07307555 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01779812 0,07295106 ! neural nucleus development GO:0048857 14 6 0,000 0,01779812 0,072827 ! response to UV-C GO:0010225 11 6 0,000 0,01779812 0,07270335 ! astrocyte development GO:0014002 15 6 0,000 0,01779812 0,07258012 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01779812 0,07245732 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01779812 0,07233492 ! interaction with symbiont GO:0051702 13 6 0,000 0,01779812 0,07221294 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01779812 0,07209137 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01779812 0,07197021 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01779812 0,07184945 ! response to copper ion GO:0046688 10 6 0,000 0,01779812 0,0717291 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01779812 0,07160915 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01779812 0,0714896 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01779812 0,07137046 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01779812 0,0712517 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01779812 0,07113334 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01779812 0,07101538 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01779812 0,0708978 ! hair follicle maturation GO:0048820 7 6 0,000 0,01779812 0,07078062 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01779812 0,07066382 ! Schwann cell development GO:0014044 15 6 0,000 0,01779812 0,0705474 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01779812 0,07043137 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01779812 0,07031572 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01779812 0,07020045 ! subpallium development GO:0021544 10 6 0,000 0,01779812 0,07008555 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01779812 0,06997103 ! histone ubiquitination GO:0016574 8 6 0,000 0,01779812 0,06985689 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01779812 0,06974312 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01779812 0,06962971 ! G2 phase GO:0051319 16 6 0,000 0,01779812 0,06951668 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01779812 0,06940401 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01779812 0,0692917 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01779812 0,06917976 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01779812 0,06906818 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01779812 0,06895696 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01779812 0,0688461 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01779812 0,06873559 ! receptor internalization GO:0031623 10 6 0,000 0,01779812 0,06862544 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01779812 0,06851564 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01779812 0,06840619 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01779812 0,06829709 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01779812 0,06818833 ! protein deubiquitination GO:0016579 14 6 0,000 0,01779812 0,06807993 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01779812 0,06797186 ! protein destabilization GO:0031648 9 6 0,000 0,01779812 0,06786414 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01779812 0,06775676 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01779812 0,06764972 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01779812 0,06754302 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01779812 0,06743665 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01779812 0,06733062 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01779812 0,06722492 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01779812 0,06711955 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01779812 0,06701451 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01779812 0,0669098 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01779812 0,06680542 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01779812 0,06670136 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01779812 0,06659763 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01779812 0,06649421 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01779812 0,06639112 ! catecholamine transport GO:0051937 9 6 0,000 0,01779812 0,06628835 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01779812 0,06618589 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01779812 0,06608376 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01779812 0,06598193 ! maternal placenta development GO:0001893 12 6 0,000 0,01779812 0,06588042 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01779812 0,06577922 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01779812 0,06567833 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01779812 0,06557775 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01779812 0,06547748 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01779812 0,06537752 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01779812 0,06527786 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01779812 0,0651785 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01819814 0,06654212 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,01819814 0,06644115 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,01971323 0,07186368 ! tRNA transcription GO:0009304 14 7 0,000 0,02073386 0,07547 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02073386 0,075356 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02073386 0,07524234 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02073386 0,07512902 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02073386 0,07501605 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02073386 0,07490341 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02073386 0,07479111 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02073386 0,07467915 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02073386 0,07456752 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02073386 0,07445623 ! prostate gland development GO:0030850 13 7 0,000 0,02073386 0,07434526 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02073386 0,07423463 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02073386 0,07412433 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02073386 0,07401435 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02073386 0,0739047 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02073386 0,07379537 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02073386 0,07368637 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02073386 0,07357769 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02073386 0,07346933 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02073386 0,07336128 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02073386 0,07325356 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02073386 0,07314615 ! glycolipid transport GO:0046836 10 7 0,000 0,02073386 0,07303905 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02073386 0,07293227 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02073386 0,0728258 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02073386 0,07271964 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02073386 0,07261379 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02073386 0,07250824 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02073386 0,07240301 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02073386 0,07229808 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02073386 0,07219345 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02073386 0,07208912 ! pericardium development GO:0060039 14 7 0,000 0,02073386 0,0719851 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02073386 0,07188137 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02073386 0,07177795 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02073386 0,07167482 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02073386 0,07157198 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02073386 0,07146944 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02073386 0,0713672 ! lipoprotein transport GO:0042953 14 7 0,000 0,02073386 0,07126525 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02073386 0,07116358 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02073386 0,07106221 ! rhythmic behavior GO:0007622 15 7 0,000 0,02073386 0,07096113 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02073386 0,07086033 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02073386 0,07075982 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02073386 0,07065959 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02073386 0,07055965 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02073386 0,07045999 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02073386 0,07036061 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02073386 0,07026151 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02073386 0,07016269 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02073386 0,07006415 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02073386 0,06996588 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02073386 0,06986789 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02073386 0,06977017 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02073386 0,06967273 ! spinal cord patterning GO:0021511 13 7 0,000 0,02073386 0,06957555 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02073386 0,06947865 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02073386 0,06938202 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02073386 0,06928566 ! adrenal gland development GO:0030325 17 7 0,000 0,02073386 0,06918956 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02073386 0,06909373 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02073386 0,06899816 ! ovulation GO:0030728 9 7 0,000 0,02073386 0,06890286 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02073386 0,06880782 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02073386 0,06871305 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02073386 0,06861853 ! microtubule nucleation GO:0007020 20 7 0,000 0,02073386 0,06852427 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02073386 0,06843028 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02073386 0,06833654 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02073386 0,06824305 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02073386 0,06814982 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02073386 0,06805685 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02073386 0,06796413 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02073386 0,06787166 ! galactose metabolic process GO:0006012 13 7 0,000 0,02073386 0,06777945 ! vesicle fusion GO:0006906 17 7 0,000 0,02073386 0,06768748 ! response to dietary excess GO:0002021 8 7 0,000 0,02073386 0,06759576 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02073386 0,06750429 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02073386 0,06741307 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02073386 0,06732209 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02073386 0,06723136 ! organ growth GO:0035265 15 7 0,000 0,02073386 0,06714088 ! purine salvage GO:0043101 10 7 0,000 0,02073386 0,06705063 ! nucleoside transport GO:0015858 8 7 0,000 0,02073386 0,06696063 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02073386 0,06687087 ! parturition GO:0007567 14 7 0,000 0,02073386 0,06678135 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02073386 0,06669207 ! rRNA modification GO:0000154 14 7 0,000 0,02073386 0,06660303 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02073386 0,06651423 ! spindle checkpoint GO:0031577 15 7 0,000 0,02073386 0,06642566 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02073386 0,06633733 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02073386 0,06624923 ! macrophage differentiation GO:0030225 11 7 0,000 0,02073386 0,06616137 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02073386 0,06607374 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02073386 0,06598634 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02073386 0,06589917 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02073386 0,06581223 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02073386 0,06572552 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02073386 0,06563904 ! fibrinolysis GO:0042730 10 7 0,000 0,02073386 0,06555279 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02073386 0,06546676 ! eating behavior GO:0042755 7 7 0,000 0,02073386 0,06538096 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02073386 0,06529538 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02073386 0,06521003 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02073386 0,0651249 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02073386 0,06503999 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02073386 0,0649553 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02073386 0,06487083 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02073386 0,06478659 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02073386 0,06470256 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02073386 0,06461875 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02073386 0,06453515 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02073386 0,06445177 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02073386 0,06436861 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02073386 0,06428566 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02073386 0,06420292 ! regulation of meiosis GO:0040020 12 7 0,000 0,02073386 0,0641204 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02073386 0,06403809 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02073386 0,06395599 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02073386 0,0638741 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02073386 0,06379242 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02073386 0,06371095 ! transcription termination GO:0006353 13 7 0,000 0,02073386 0,06362968 ! response to tumor cell GO:0002347 13 7 0,000 0,02073386 0,06354863 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02073386 0,06346778 ! anaphase GO:0051322 17 7 0,000 0,02073386 0,06338713 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02073386 0,06330669 ! axonal fasciculation GO:0007413 18 7 0,000 0,02073386 0,06322645 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02073386 0,06314642 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02073386 0,06306659 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02073386 0,06298696 ! diuresis GO:0030146 12 7 0,000 0,02073386 0,06290753 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02073386 0,0628283 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02073386 0,06274927 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02073386 0,06267044 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02073386 0,06259181 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02073386 0,06251337 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02073386 0,06243513 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02073386 0,06235709 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02073386 0,06227924 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02073386 0,06220159 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02073386 0,06212412 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02073386 0,06204686 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02073386 0,06196978 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02073386 0,06189289 ! lymph node development GO:0048535 10 7 0,000 0,02073386 0,0618162 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02073386 0,06173969 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02073386 0,06166338 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02073386 0,06158725 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02073386 0,06151131 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02073386 0,06143556 ! adult feeding behavior GO:0008343 9 7 0,000 0,02073386 0,06135999 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02073386 0,06128461 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02073386 0,06120941 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02073386 0,0611344 ! muscle adaptation GO:0043500 14 7 0,000 0,02073386 0,06105957 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02073386 0,06098493 ! retina homeostasis GO:0001895 12 7 0,000 0,02073386 0,06091047 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02073386 0,06083619 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02073386 0,06076209 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02073386 0,06068817 ! protein prenylation GO:0018342 18 7 0,000 0,02073386 0,06061443 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02073386 0,06054086 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02073386 0,06046748 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02073386 0,06039428 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02075174 0,06037325 GO:0090046|regulation of transcription regulator activity, ! organelle localization GO:0051640 136 74 1,000 0,02075174 0,06030033 ! protein oligomerization GO:0051259 139 78 1,000 0,02289567 0,06644993 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02366093 0,06858818 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02366093 0,06850565 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02366093 0,06842331 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02366093 0,06834117 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02366093 0,06825922 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02366093 0,06817748 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02366093 0,06809592 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02366093 0,06801457 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02366093 0,0679334 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02366093 0,06785243 ! meiotic prophase I GO:0007128 13 8 0,000 0,02366093 0,06777166 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02366093 0,06769107 ! oligopeptide transport GO:0006857 15 8 0,000 0,02366093 0,06761068 ! UTP metabolic process GO:0046051 8 8 0,000 0,02366093 0,06753048 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02366093 0,06745046 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02366093 0,06737064 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02366093 0,06729101 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02366093 0,06721156 ! succinate metabolic process GO:0006105 14 8 0,000 0,02366093 0,0671323 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02366093 0,06705323 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02366093 0,06697434 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02366093 0,06689564 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02366093 0,06681713 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02366093 0,0667388 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02366093 0,06666065 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02366093 0,06658268 ! reflex GO:0060004 16 8 0,000 0,02366093 0,0665049 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02366093 0,0664273 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02366093 0,06634987 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02366093 0,06627263 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02366093 0,06619557 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02366093 0,06611869 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02366093 0,06604199 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02366093 0,06596546 ! pigment granule organization GO:0048753 16 8 0,000 0,02366093 0,06588911 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02366093 0,06581294 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02366093 0,06573694 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02366093 0,06566112 ! histidine metabolic process GO:0006547 16 8 0,000 0,02366093 0,06558547 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02366093 0,06551 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02366093 0,0654347 ! glycine catabolic process GO:0006546 13 8 0,000 0,02366093 0,06535958 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02366093 0,06528462 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02366093 0,06520984 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02366093 0,06513523 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02366093 0,06506079 ! melanin metabolic process GO:0006582 15 8 0,000 0,02366093 0,06498652 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02366093 0,06491242 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02366093 0,06483849 ! macrophage activation GO:0042116 12 8 0,000 0,02366093 0,06476472 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02366093 0,06469113 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02366093 0,0646177 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02366093 0,06454444 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02366093 0,06447134 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02366093 0,06439841 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02366093 0,06432564 ! osteoblast development GO:0002076 16 8 0,000 0,02366093 0,06425304 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02366093 0,0641806 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02366093 0,06410832 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02366093 0,06403621 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02366093 0,06396426 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02366093 0,06389247 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02366093 0,06382084 ! response to UV-B GO:0010224 16 8 0,000 0,02366093 0,06374938 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02366093 0,06367807 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02366093 0,06360692 ! intermediate filament organization GO:0045109 12 8 0,000 0,02366093 0,06353593 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02366093 0,0634651 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02366093 0,06339442 ! cellular extravasation GO:0045123 12 8 0,000 0,02366093 0,06332391 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02366093 0,06325355 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02366093 0,06318334 ! response to antibiotic GO:0046677 11 8 0,000 0,02366093 0,0631133 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02366093 0,0630434 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02366093 0,06297366 ! DNA topological change GO:0006265 12 8 0,000 0,02366093 0,06290408 ! response to tropane GO:0014073 15 8 0,000 0,02366093 0,06283465 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02366093 0,06276537 ! melanosome transport GO:0032402 13 8 0,000 0,02366093 0,06269625 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02366093 0,06262727 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02366093 0,06255845 ! mast cell activation GO:0045576 14 8 0,000 0,02366093 0,06248978 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02366093 0,06242126 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02366093 0,06235289 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02366093 0,06228467 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02366093 0,0622166 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02366093 0,06214868 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02366093 0,06208091 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02366093 0,06201328 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02366093 0,0619458 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02366093 0,06187847 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02366093 0,06181128 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02366093 0,06174424 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02366093 0,06167735 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02366093 0,0616106 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02366093 0,06154399 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02366093 0,06147753 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02366093 0,06141121 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02366093 0,06134503 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02366093 0,061279 ! hormone catabolic process GO:0042447 17 8 0,000 0,02366093 0,06121311 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02366093 0,06114736 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02366093 0,06108175 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02366093 0,06101628 ! ATP catabolic process GO:0006200 11 8 0,000 0,02366093 0,06095096 ! blastocyst growth GO:0001832 19 8 0,000 0,02366093 0,06088577 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02366093 0,06082072 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02366093 0,06075581 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02366093 0,06069104 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02366093 0,0606264 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02366093 0,06056191 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02366093 0,06049755 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02366093 0,06043333 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02366093 0,06036924 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02366093 0,06030529 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02366093 0,06024147 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02366093 0,06017779 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02366093 0,06011425 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02366093 0,06005084 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02366093 0,05998756 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02366093 0,05992441 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02366093 0,0598614 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,02400051 0,06065675 ! response to metal ion GO:0010038 140 80 1,000 0,02400051 0,0605931 ! response to hypoxia GO:0001666 171 81 1,000 0,02456101 0,06194319 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,02456101 0,06187832 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,02512686 0,06323769 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,02512686 0,06317161 ! response to oxygen levels GO:0070482 176 83 1,000 0,02569802 0,06454012 ! regulation of lyase activity GO:0051339 160 83 1,000 0,02569802 0,06447282 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,02627445 0,06585034 ! negative regulation of growth GO:0045926 155 84 1,000 0,02627445 0,06578181 ! axon extension GO:0048675 15 9 0,000 0,02657934 0,06647598 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02657934 0,06640695 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02657934 0,06633807 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02657934 0,06626932 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02657934 0,06620072 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02657934 0,06613226 ! phosphate transport GO:0006817 19 9 0,000 0,02657934 0,06606394 ! reproductive behavior GO:0019098 19 9 0,000 0,02657934 0,06599576 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02657934 0,06592773 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02657934 0,06585983 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02657934 0,06579207 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02657934 0,06572446 ! GTP metabolic process GO:0046039 9 9 0,000 0,02657934 0,06565698 ! RNA methylation GO:0001510 15 9 0,000 0,02657934 0,06558964 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02657934 0,06552243 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02657934 0,06545537 ! artery development GO:0060840 24 9 0,000 0,02657934 0,06538844 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02657934 0,06532165 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02657934 0,065255 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02657934 0,06518848 ! chemosensory behavior GO:0007635 20 9 0,000 0,02657934 0,06512209 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02657934 0,06505584 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02657934 0,06498973 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02657934 0,06492375 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02657934 0,06485791 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02657934 0,06479219 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02657934 0,06472661 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02657934 0,06466117 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02657934 0,06459585 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02657934 0,06453067 ! protein targeting to ER GO:0045047 22 9 0,000 0,02657934 0,06446562 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02657934 0,0644007 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02657934 0,06433591 ! T cell selection GO:0045058 23 9 0,000 0,02657934 0,06427125 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02657934 0,06420672 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02657934 0,06414232 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02657934 0,06407805 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02657934 0,06401391 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02657934 0,0639499 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02657934 0,06388601 ! mannose metabolic process GO:0006013 13 9 0,000 0,02657934 0,06382225 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02657934 0,06375862 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02657934 0,06369512 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02657934 0,06363174 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02657934 0,06356848 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02657934 0,06350536 ! ruffle organization GO:0031529 15 9 0,000 0,02657934 0,06344236 ! retinol metabolic process GO:0042572 18 9 0,000 0,02657934 0,06337948 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02657934 0,06331673 ! behavioral fear response GO:0001662 22 9 0,000 0,02657934 0,0632541 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02657934 0,0631916 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02657934 0,06312922 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02657934 0,06306696 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02657934 0,06300482 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02657934 0,06294281 ! segment specification GO:0007379 13 9 0,000 0,02657934 0,06288092 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02657934 0,06281915 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02657934 0,0627575 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02657934 0,06269598 ! response to amine stimulus GO:0014075 13 9 0,000 0,02657934 0,06263457 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02657934 0,06257328 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02657934 0,06251212 ! erythrocyte development GO:0048821 15 9 0,000 0,02657934 0,06245107 ! gas homeostasis GO:0033483 16 9 0,000 0,02657934 0,06239014 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02657934 0,06232933 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02657934 0,06226864 ! renal water homeostasis GO:0003091 14 9 0,000 0,02657934 0,06220807 ! postreplication repair GO:0006301 22 9 0,000 0,02657934 0,06214761 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02657934 0,06208728 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02657934 0,06202706 ! icosanoid secretion GO:0032309 15 9 0,000 0,02657934 0,06196695 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02657934 0,06190697 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02657934 0,06184709 ! regulation of cell division GO:0051302 15 9 0,000 0,02657934 0,06178734 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02657934 0,0617277 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02657934 0,06166817 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02657934 0,06160876 ! sterol catabolic process GO:0016127 11 9 0,000 0,02657934 0,06154947 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02657934 0,06149028 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02657934 0,06143122 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02657934 0,06137226 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02657934 0,06131342 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02657934 0,06125469 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02657934 0,06119607 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02657934 0,06113757 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02657934 0,06107917 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02657934 0,06102089 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02657934 0,06096272 ! purine base metabolic process GO:0006144 21 9 0,000 0,02657934 0,06090466 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02657934 0,06084671 ! pigment granule transport GO:0051904 17 9 0,000 0,02657934 0,06078887 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02657934 0,06073114 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02657934 0,06067353 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02657934 0,06061601 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02657934 0,06055861 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02657934 0,06050132 ! mitochondrion localization GO:0051646 15 9 0,000 0,02657934 0,06044414 ! response to unfolded protein GO:0006986 131 85 1,000 0,02685611 0,06101587 ! response to inorganic substance GO:0010035 153 86 1,000 0,02744298 0,06229038 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,028035 0,06357419 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,02863216 0,06486721 ! regulation of DNA binding GO:0051101 155 88 1,000 0,02863216 0,06480619 ! gland development GO:0048732 206 88 1,000 0,02863216 0,06474528 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02923441 0,06604507 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02948913 0,06655801 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02948913 0,06649563 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02948913 0,06643337 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02948913 0,06637123 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02948913 0,0663092 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02948913 0,06624729 ! synapsis GO:0007129 13 10 0,000 0,02948913 0,06618549 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02948913 0,0661238 ! N-glycan processing GO:0006491 20 10 0,000 0,02948913 0,06606224 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02948913 0,06600078 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02948913 0,06593944 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02948913 0,06587822 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02948913 0,06581711 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02948913 0,06575611 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02948913 0,06569522 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02948913 0,06563445 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02948913 0,06557379 ! androgen metabolic process GO:0008209 17 10 0,000 0,02948913 0,06551324 ! phospholipid efflux GO:0033700 16 10 0,000 0,02948913 0,06545281 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02948913 0,06539248 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02948913 0,06533227 ! pathogenesis GO:0009405 13 10 0,000 0,02948913 0,06527216 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02948913 0,06521217 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02948913 0,06515229 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02948913 0,06509252 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02948913 0,06503285 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02948913 0,0649733 ! endoderm development GO:0007492 16 10 0,000 0,02948913 0,06491385 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02948913 0,06485452 ! arginine catabolic process GO:0006527 13 10 0,000 0,02948913 0,06479529 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02948913 0,06473617 ! proline metabolic process GO:0006560 13 10 0,000 0,02948913 0,06467716 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02948913 0,06461825 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02948913 0,06455946 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02948913 0,06450077 ! V(D)J recombination GO:0033151 28 10 0,000 0,02948913 0,06444218 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02948913 0,0643837 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02948913 0,06432533 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02948913 0,06426707 ! B cell proliferation GO:0042100 18 10 0,000 0,02948913 0,06420891 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02948913 0,06415085 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02948913 0,0640929 ! multicellular organism growth GO:0035264 18 10 0,000 0,02948913 0,06403506 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02948913 0,06397732 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02948913 0,06391968 ! epithelial cell development GO:0002064 20 10 0,000 0,02948913 0,06386214 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02948913 0,06380471 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02948913 0,06374739 ! macroautophagy GO:0016236 17 10 0,000 0,02948913 0,06369016 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02948913 0,06363304 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02948913 0,06357602 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02948913 0,06351911 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02948913 0,06346229 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02948913 0,06340558 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02948913 0,06334897 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02948913 0,06329246 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02948913 0,06323604 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02948913 0,06317974 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02948913 0,06312353 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02948913 0,06306742 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02948913 0,06301141 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02948913 0,06295549 ! response to dsRNA GO:0043331 20 10 0,000 0,02948913 0,06289968 ! DNA ligation GO:0006266 19 10 0,000 0,02948913 0,06284397 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02948913 0,06278836 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02948913 0,06273284 ! melanosome localization GO:0032400 16 10 0,000 0,02948913 0,06267742 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02948913 0,0626221 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02948913 0,06256688 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02948913 0,06251176 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02948913 0,06245673 ! mRNA cleavage GO:0006379 17 10 0,000 0,02948913 0,0624018 ! protein sumoylation GO:0016925 15 10 0,000 0,02948913 0,06234696 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02948913 0,06229222 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02948913 0,06223758 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02948913 0,06218303 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02948913 0,06212858 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02948913 0,06207423 ! salivary gland development GO:0007431 27 10 0,000 0,02948913 0,06201997 ! prophase GO:0051324 15 10 0,000 0,02948913 0,0619658 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02948913 0,06191173 ! apical protein localization GO:0045176 15 10 0,000 0,02948913 0,06185775 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02948913 0,06180387 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02948913 0,06175008 ! midbrain development GO:0030901 13 10 0,000 0,02948913 0,06169638 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02948913 0,06164278 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02948913 0,06158927 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02948913 0,06153586 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02948913 0,06148253 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02948913 0,0614293 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02948913 0,06137616 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02948913 0,06132311 ! detection of calcium ion GO:0005513 23 10 0,000 0,02948913 0,06127016 ! oocyte development GO:0048599 17 10 0,000 0,02948913 0,06121729 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02948913 0,06116452 ! blastocyst formation GO:0001825 17 10 0,000 0,02948913 0,06111184 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02948913 0,06105924 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02948913 0,06100674 ! activation of innate immune response GO:0002218 12 10 0,000 0,02948913 0,06095433 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02948913 0,06090201 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02948913 0,06084978 ! response to nicotine GO:0035094 20 10 0,000 0,02948913 0,06079764 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02948913 0,06074558 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02948913 0,06069362 ! ossification GO:0001503 188 90 1,000 0,02984172 0,06136682 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,02984172 0,06131442 ! bone development GO:0060348 189 91 1,000 0,03045405 0,06251916 ! response to protein stimulus GO:0051789 149 91 1,000 0,03045405 0,06246586 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,03169365 0,06495309 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03169365 0,06489782 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03169365 0,06484263 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03232085 0,06606964 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03239031 0,06615543 ! respiratory burst GO:0045730 17 11 0,000 0,03239031 0,06609932 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03239031 0,0660433 ! neuron fate specification GO:0048665 17 11 0,000 0,03239031 0,06598738 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03239031 0,06593155 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03239031 0,06587582 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03239031 0,06582018 ! thyroid gland development GO:0030878 26 11 0,000 0,03239031 0,06576464 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03239031 0,06570919 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03239031 0,06565383 ! response to pain GO:0048265 24 11 0,000 0,03239031 0,06559856 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03239031 0,06554339 ! T cell proliferation GO:0042098 26 11 0,000 0,03239031 0,06548831 ! bone resorption GO:0045453 16 11 0,000 0,03239031 0,06543333 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,03239031 0,06537843 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03239031 0,06532363 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03239031 0,06526892 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03239031 0,0652143 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03239031 0,06515978 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03239031 0,06510534 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03239031 0,065051 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03239031 0,06499674 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03239031 0,06494258 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03239031 0,0648885 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03239031 0,06483452 ! lipid digestion GO:0044241 18 11 0,000 0,03239031 0,06478063 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03239031 0,06472682 ! UV protection GO:0009650 19 11 0,000 0,03239031 0,06467311 ! adult heart development GO:0007512 14 11 0,000 0,03239031 0,06461948 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03239031 0,06456594 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03239031 0,06451249 ! temperature homeostasis GO:0001659 17 11 0,000 0,03239031 0,06445913 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03239031 0,06440586 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03239031 0,06435268 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03239031 0,06429958 ! regulation of organ growth GO:0046620 13 11 0,000 0,03239031 0,06424657 ! pigment granule localization GO:0051875 20 11 0,000 0,03239031 0,06419365 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03239031 0,06414082 ! vasoconstriction GO:0042310 18 11 0,000 0,03239031 0,06408807 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03239031 0,06403541 ! embryonic axis specification GO:0000578 18 11 0,000 0,03239031 0,06398284 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03239031 0,06393035 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03239031 0,06387795 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03239031 0,06382563 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03239031 0,0637734 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03239031 0,06372125 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03239031 0,06366919 ! zymogen activation GO:0031638 15 11 0,000 0,03239031 0,06361722 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03239031 0,06356533 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03239031 0,06351352 ! nucleosome positioning GO:0016584 15 11 0,000 0,03239031 0,0634618 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03239031 0,06341017 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03239031 0,06335861 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03239031 0,06330714 ! acid secretion GO:0046717 18 11 0,000 0,03239031 0,06325576 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03239031 0,06320446 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03239031 0,06315324 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03239031 0,0631021 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03239031 0,06305105 ! oocyte differentiation GO:0009994 18 11 0,000 0,03239031 0,06300008 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03239031 0,06294919 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03239031 0,06289838 ! cholesterol efflux GO:0033344 19 11 0,000 0,03239031 0,06284766 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03239031 0,06279701 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03239031 0,06274645 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03239031 0,06269597 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03239031 0,06264557 ! embryonic gut development GO:0048566 15 11 0,000 0,03239031 0,06259526 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03239031 0,06254502 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03239031 0,06249486 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03239031 0,06244479 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03239031 0,06239479 ! defense response to fungus GO:0050832 13 11 0,000 0,03239031 0,06234487 ! lysogeny GO:0030069 21 11 0,000 0,03239031 0,06229504 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03239031 0,06224528 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03239031 0,06219561 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03239031 0,06214601 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03239031 0,06209649 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03239031 0,06204705 ! forebrain development GO:0030900 188 95 1,000 0,03295294 0,06307459 ! mRNA transport GO:0051028 169 96 1,000 0,03358987 0,06424263 ! protein ubiquitination GO:0016567 217 97 1,000 0,03423162 0,06541802 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03528292 0,06737358 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03528292 0,06732015 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03528292 0,06726681 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03528292 0,06721355 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,03528292 0,06716037 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03528292 0,06710728 ! cartilage condensation GO:0001502 20 12 0,000 0,03528292 0,06705427 ! mating GO:0007618 17 12 0,000 0,03528292 0,06700135 ! protein complex disassembly GO:0043241 27 12 0,000 0,03528292 0,06694851 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03528292 0,06689575 ! hippocampus development GO:0021766 26 12 0,000 0,03528292 0,06684308 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03528292 0,06679049 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03528292 0,06673798 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03528292 0,06668555 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03528292 0,06663321 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03528292 0,06658095 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03528292 0,06652877 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03528292 0,06647667 ! drug transport GO:0015893 16 12 0,000 0,03528292 0,06642466 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03528292 0,06637272 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03528292 0,06632087 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03528292 0,06626909 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03528292 0,0662174 ! focal adhesion formation GO:0048041 35 12 0,000 0,03528292 0,06616579 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03528292 0,06611426 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03528292 0,06606281 ! forebrain cell migration GO:0021885 21 12 0,000 0,03528292 0,06601144 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03528292 0,06596015 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03528292 0,06590894 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03528292 0,0658578 ! entry into host cell GO:0030260 32 12 0,000 0,03528292 0,06580675 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03528292 0,06575578 ! monoamine transport GO:0015844 18 12 0,000 0,03528292 0,06570488 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03528292 0,06565407 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03528292 0,06560333 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03528292 0,06555267 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03528292 0,06550209 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03528292 0,06545159 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03528292 0,06540116 ! protein homotetramerization GO:0051289 21 12 0,000 0,03528292 0,06535082 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03528292 0,06530055 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03528292 0,06525035 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03528292 0,06520024 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03528292 0,0651502 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03528292 0,06510024 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03528292 0,06505035 ! cranial nerve development GO:0021545 20 12 0,000 0,03528292 0,06500054 ! fucose catabolic process GO:0019317 22 12 0,000 0,03528292 0,06495081 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03528292 0,06490115 ! histone acetylation GO:0016573 26 12 0,000 0,03528292 0,06485157 ! histone methylation GO:0016571 26 12 0,000 0,03528292 0,06480207 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03528292 0,06475264 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03528292 0,06470328 ! gland morphogenesis GO:0022612 29 12 0,000 0,03528292 0,06465401 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03528292 0,0646048 ! T cell homeostasis GO:0043029 25 12 0,000 0,03528292 0,06455567 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03528292 0,06450662 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03528292 0,06445764 ! spleen development GO:0048536 22 12 0,000 0,03528292 0,06440873 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03528292 0,0643599 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03528292 0,06431114 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03528292 0,06426246 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03528292 0,06421385 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03528292 0,06416531 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03528292 0,06411685 ! response to cold GO:0009409 17 12 0,000 0,03528292 0,06406846 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03528292 0,06402014 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03528292 0,0639719 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,03552945 0,06437037 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03816698 0,06909688 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03816698 0,06904493 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03816698 0,06899305 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03816698 0,06894125 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03816698 0,06888954 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03816698 0,06883789 ! lipid localization GO:0010876 28 13 0,000 0,03816698 0,06878633 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,03816698 0,06873484 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03816698 0,06868343 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03816698 0,0686321 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03816698 0,06858084 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03816698 0,06852966 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03816698 0,06847856 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03816698 0,06842753 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03816698 0,06837658 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03816698 0,06832571 ! methionine metabolic process GO:0006555 27 13 0,000 0,03816698 0,06827491 ! plasma membrane organization GO:0007009 24 13 0,000 0,03816698 0,06822418 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03816698 0,06817353 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03816698 0,06812296 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03816698 0,06807246 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03816698 0,06802204 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03816698 0,06797169 ! response to X-ray GO:0010165 25 13 0,000 0,03816698 0,06792141 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03816698 0,06787121 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03816698 0,06782109 ! exocrine system development GO:0035272 32 13 0,000 0,03816698 0,06777103 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03816698 0,06772106 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03816698 0,06767115 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03816698 0,06762132 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03816698 0,06757156 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03816698 0,06752188 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03816698 0,06747226 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03816698 0,06742272 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03816698 0,06737326 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03816698 0,06732386 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03816698 0,06727454 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03816698 0,06722529 ! ribosome assembly GO:0042255 17 13 0,000 0,03816698 0,06717612 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03816698 0,06712701 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03816698 0,06707798 ! chromatin silencing GO:0006342 26 13 0,000 0,03816698 0,06702902 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03816698 0,06698012 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03816698 0,06693131 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03816698 0,06688256 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03816698 0,06683388 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03816698 0,06678527 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03816698 0,06673674 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03816698 0,06668827 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03816698 0,06663988 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03816698 0,06659155 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03816698 0,0665433 ! embryonic placenta development GO:0001892 23 13 0,000 0,03816698 0,06649511 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03816698 0,066447 ! insulin secretion GO:0030073 23 13 0,000 0,03816698 0,06639895 ! actin filament polymerization GO:0030041 24 13 0,000 0,03816698 0,06635098 ! acrosome reaction GO:0007340 18 13 0,000 0,03816698 0,06630307 ! rRNA transcription GO:0009303 25 14 0,000 0,04104251 0,07124695 ! lactation GO:0007595 26 14 0,000 0,04104251 0,07119559 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,04104251 0,07114429 ! reproductive cellular process GO:0048610 20 14 0,000 0,04104251 0,07109307 ! tRNA modification GO:0006400 20 14 0,000 0,04104251 0,07104193 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04104251 0,07099085 ! regulation of S phase GO:0033261 23 14 0,000 0,04104251 0,07093985 ! water transport GO:0006833 21 14 0,000 0,04104251 0,07088893 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04104251 0,07083808 ! non-recombinational repair GO:0000726 25 14 0,000 0,04104251 0,0707873 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04104251 0,07073659 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04104251 0,07068595 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04104251 0,07063539 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04104251 0,0705849 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04104251 0,07053448 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04104251 0,07048414 ! palate development GO:0060021 31 14 0,000 0,04104251 0,07043386 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04104251 0,07038366 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04104251 0,07033353 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04104251 0,07028347 ! arginine metabolic process GO:0006525 17 14 0,000 0,04104251 0,07023348 ! regulation of heart rate GO:0002027 24 14 0,000 0,04104251 0,07018357 ! organic alcohol transport GO:0015850 29 14 0,000 0,04104251 0,07013372 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04104251 0,07008394 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04104251 0,07003424 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04104251 0,0699846 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04104251 0,06993504 ! L-amino acid transport GO:0015807 30 14 0,000 0,04104251 0,06988555 ! bone mineralization GO:0030282 17 14 0,000 0,04104251 0,06983612 ! stem cell development GO:0048864 43 14 0,000 0,04104251 0,06978677 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04104251 0,06973748 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04104251 0,06968827 ! cerebellum development GO:0021549 21 14 0,000 0,04104251 0,06963912 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04104251 0,06959005 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04104251 0,06954104 ! response to gamma radiation GO:0010332 28 14 0,000 0,04104251 0,0694921 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04104251 0,06944323 ! cofactor transport GO:0051181 26 14 0,000 0,04104251 0,06939443 ! NADP metabolic process GO:0006739 24 14 0,000 0,04104251 0,0693457 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04104251 0,06929704 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04104251 0,06924844 ! intestinal absorption GO:0050892 25 14 0,000 0,04104251 0,06919991 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04104251 0,06915145 ! oxygen transport GO:0015671 21 14 0,000 0,04104251 0,06910306 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04104251 0,06905474 ! male genitalia development GO:0030539 24 14 0,000 0,04104251 0,06900648 ! regulation of axon extension GO:0030516 37 14 0,000 0,04104251 0,06895829 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,04104251 0,06891017 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04104251 0,06886212 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04390954 0,07362115 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04390954 0,07356988 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04390954 0,07351868 ! superoxide anion generation GO:0042554 20 15 0,000 0,04390954 0,07346756 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04390954 0,0734165 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04390954 0,07336552 ! copper ion transport GO:0006825 20 15 0,000 0,04390954 0,07331461 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04390954 0,07326377 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04390954 0,07321299 ! sulfate transport GO:0008272 23 15 0,000 0,04390954 0,07316229 ! response to cAMP GO:0051591 22 15 0,000 0,04390954 0,07311166 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04390954 0,0730611 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04390954 0,07301061 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04390954 0,07296019 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04390954 0,07290983 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04390954 0,07285955 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04390954 0,07280934 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04390954 0,07275919 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04390954 0,07270912 ! pituitary gland development GO:0021983 29 15 0,000 0,04390954 0,07265911 ! vesicle coating GO:0006901 33 15 0,000 0,04390954 0,07260917 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04390954 0,07255931 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04390954 0,07250951 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04390954 0,07245977 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04390954 0,07241011 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04390954 0,07236051 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04390954 0,07231099 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04390954 0,07226152 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04390954 0,07221213 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04390954 0,07216281 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04390954 0,07211355 ! histone deacetylation GO:0016575 20 15 0,000 0,04390954 0,07206436 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04390954 0,07201523 ! tissue regeneration GO:0042246 26 15 0,000 0,04390954 0,07196618 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04390954 0,07191719 ! water homeostasis GO:0030104 27 15 0,000 0,04390954 0,07186826 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04390954 0,07181941 ! muscle maintenance GO:0046716 26 15 0,000 0,04390954 0,07177062 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04390954 0,07172189 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04390954 0,07167324 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04390954 0,07162464 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04390954 0,07157612 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04390954 0,07152766 ! cell killing GO:0001906 29 15 0,000 0,04390954 0,07147926 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04390954 0,07143093 ! detection of bacterium GO:0016045 18 15 0,000 0,04390954 0,07138267 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04390954 0,07133447 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04390954 0,07128634 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04390954 0,07123827 ! peptide hormone processing GO:0016486 23 15 0,000 0,04390954 0,07119026 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04676809 0,07577375 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04676809 0,07572276 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04676809 0,07567184 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04676809 0,07562099 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04676809 0,0755702 ! bone remodeling GO:0046849 27 16 0,000 0,04676809 0,07551948 ! filopodium assembly GO:0046847 32 16 0,000 0,04676809 0,07546883 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04676809 0,07541825 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04676809 0,07536773 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04676809 0,07531729 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04676809 0,07526691 ! startle response GO:0001964 28 16 0,000 0,04676809 0,0752166 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04676809 0,07516635 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04676809 0,07511617 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04676809 0,07506606 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04676809 0,07501602 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04676809 0,07496604 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04676809 0,07491613 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04676809 0,07486628 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04676809 0,07481651 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04676809 0,07476679 ! response to osmotic stress GO:0006970 25 16 0,000 0,04676809 0,07471715 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04676809 0,07466757 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04676809 0,07461805 ! fructose metabolic process GO:0006000 25 16 0,000 0,04676809 0,07456861 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04676809 0,07451922 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04676809 0,0744699 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04676809 0,07442065 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04676809 0,07437146 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04676809 0,07432234 ! axon cargo transport GO:0008088 43 16 0,000 0,04676809 0,07427328 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04676809 0,07422429 ! DNA replication initiation GO:0006270 27 16 0,000 0,04676809 0,07417536 ! neuron recognition GO:0008038 35 16 0,000 0,04676809 0,0741265 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04676809 0,0740777 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04676809 0,07402896 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04676809 0,07398029 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04676809 0,07393169 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04676809 0,07388314 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04676809 0,07383466 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04676809 0,07378625 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04676809 0,07373789 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04676809 0,0736896 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04676809 0,07364138 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04676809 0,07359322 ! defense response to virus GO:0051607 37 16 0,000 0,04676809 0,07354512 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04961819 0,07797607 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04961819 0,07792517 ! metencephalon development GO:0022037 30 17 0,000 0,04961819 0,07787434 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04961819 0,07782358 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04961819 0,07777288 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04961819 0,07772224 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04961819 0,07767168 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04961819 0,07762118 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04961819 0,07757074 ! glial cell development GO:0021782 27 17 0,000 0,04961819 0,07752037 ! limbic system development GO:0021761 36 17 0,000 0,04961819 0,07747006 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04961819 0,07741982 ! adult walking behavior GO:0007628 33 17 0,000 0,04961819 0,07736965 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04961819 0,07731954 ! heart looping GO:0001947 30 17 0,000 0,04961819 0,07726949 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04961819 0,07721951 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04961819 0,0771696 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04961819 0,07711975 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04961819 0,07706996 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04961819 0,07702024 ! glycine metabolic process GO:0006544 28 17 0,000 0,04961819 0,07697058 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04961819 0,07692098 ! NAD metabolic process GO:0019674 29 17 0,000 0,04961819 0,07687145 ! membrane budding GO:0006900 37 17 0,000 0,04961819 0,07682199 ! DNA integration GO:0015074 29 17 0,000 0,04961819 0,07677258 ! regulation of protein binding GO:0043393 33 17 0,000 0,04961819 0,07672324 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04961819 0,07667397 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04961819 0,07662475 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04961819 0,0765756 ! genitalia development GO:0048806 30 17 0,000 0,04961819 0,07652652 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04961819 0,07647749 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04961819 0,07642853 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04961819 0,07637963 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04961819 0,0763308 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04961819 0,07628202 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04961819 0,07623331 ! steroid catabolic process GO:0006706 31 17 0,000 0,04961819 0,07618466 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04961819 0,07613608 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04961819 0,07608755 ! gas transport GO:0015669 25 17 0,000 0,04961819 0,07603909 ! organic cation transport GO:0015695 31 17 0,000 0,04961819 0,07599069 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04961819 0,07594235 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04961819 0,07589407 ! microspike assembly GO:0030035 36 17 0,000 0,04961819 0,07584585 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04961819 0,07579769 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04961819 0,0757496 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05245986 0,08003705 ! neuron maturation GO:0042551 42 18 0,000 0,05245986 0,07998633 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05245986 0,07993568 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05245986 0,07988508 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05245986 0,07983456 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05245986 0,07978409 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05245986 0,07973369 ! memory GO:0007613 31 18 0,000 0,05245986 0,07968335 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05245986 0,07963308 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05245986 0,07958287 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05245986 0,07953272 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05245986 0,07948264 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05245986 0,07943262 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05245986 0,07938266 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05245986 0,07933277 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05245986 0,07928294 ! response to retinoic acid GO:0032526 26 18 0,000 0,05245986 0,07923317 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05245986 0,07918346 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05245986 0,07913381 ! response to fungus GO:0009620 21 18 0,000 0,05245986 0,07908423 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05245986 0,07903471 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05245986 0,07898525 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05245986 0,07893586 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05245986 0,07888652 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05245986 0,07883725 ! vitamin transport GO:0051180 27 18 0,000 0,05245986 0,07878804 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05245986 0,07873889 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05245986 0,0786898 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05245986 0,07864077 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05245986 0,0785918 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05245986 0,0785429 ! nerve development GO:0021675 28 18 0,000 0,05245986 0,07849405 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05245986 0,07844527 ! protein secretion GO:0009306 39 19 0,000 0,05529313 0,08263061 ! positive regulation of translation GO:0045727 30 19 0,000 0,05529313 0,08257932 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05529313 0,08252809 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05529313 0,08247693 ! skin development GO:0043588 36 19 0,000 0,05529313 0,08242583 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05529313 0,08237479 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05529313 0,08232381 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05529313 0,0822729 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05529313 0,08222205 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05529313 0,08217127 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05529313 0,08212054 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05529313 0,08206988 ! pigmentation during development GO:0048066 41 19 0,000 0,05529313 0,08201929 ! response to vitamin A GO:0033189 27 19 0,000 0,05529313 0,08196875 ! heme metabolic process GO:0042168 36 19 0,000 0,05529313 0,08191828 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05529313 0,08186787 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05529313 0,08181752 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05529313 0,08176723 ! peptide cross-linking GO:0018149 37 19 0,000 0,05529313 0,081717 ! protein export from nucleus GO:0006611 36 19 0,000 0,05529313 0,08166684 ! heart process GO:0003015 30 19 0,000 0,05529313 0,08161674 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05529313 0,0815667 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05529313 0,08151672 ! visual learning GO:0008542 36 19 0,000 0,05529313 0,0814668 ! cellular pigmentation GO:0033059 36 19 0,000 0,05529313 0,08141694 ! G1 phase GO:0051318 40 19 0,000 0,05529313 0,08136715 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05529313 0,08131741 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05529313 0,08126774 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05529313 0,08121812 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05529313 0,08116857 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05529313 0,08111907 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05529313 0,08106964 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05529313 0,08102027 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05529313 0,08097096 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05529313 0,0809217 ! cilium assembly GO:0042384 37 19 0,000 0,05529313 0,08087251 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05529313 0,08082338 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05811803 0,08490102 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05811803 0,0848495 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05811803 0,08479804 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05811803 0,08474665 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,05811803 0,08469532 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05811803 0,08464405 ! response to vitamin GO:0033273 31 20 0,000 0,05811803 0,08459285 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05811803 0,0845417 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05811803 0,08449062 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05811803 0,0844396 ! response to alkaloid GO:0043279 38 20 0,000 0,05811803 0,08438864 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05811803 0,08433774 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,05811803 0,0842869 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05811803 0,08423613 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05811803 0,08418541 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05811803 0,08413476 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,05811803 0,08408417 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05811803 0,08403364 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05811803 0,08398317 ! body fluid secretion GO:0007589 31 20 0,000 0,05811803 0,08393276 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05811803 0,08388241 ! peptide secretion GO:0002790 35 20 0,000 0,05811803 0,08383212 ! stem cell differentiation GO:0048863 53 20 0,000 0,05811803 0,08378189 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05811803 0,08373172 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05811803 0,08368161 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05811803 0,08363156 ! sensory perception of pain GO:0019233 30 20 0,000 0,05811803 0,08358157 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05811803 0,08353165 ! diencephalon development GO:0021536 34 20 0,000 0,05811803 0,08348178 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05811803 0,08343197 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05811803 0,08338221 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05811803 0,08333252 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05811803 0,08328289 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05811803 0,08323332 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05811803 0,0831838 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05811803 0,08313435 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05811803 0,08308495 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05811803 0,08303561 ! regulation of glucose import GO:0046324 29 20 0,000 0,05811803 0,08298633 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05811803 0,08293711 ! actin filament-based movement GO:0030048 43 20 0,000 0,05811803 0,08288795 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05811803 0,08283885 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05811803 0,0827898 ! negative regulation of translation GO:0017148 29 20 0,000 0,05811803 0,08274081 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05811803 0,08269188 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,05811803 0,08264301 ! regulation of cell killing GO:0031341 42 21 0,000 0,06093457 0,08659691 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06093457 0,08654579 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06093457 0,08649473 ! hormone secretion GO:0046879 38 21 0,000 0,06093457 0,08644373 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06093457 0,08639279 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06093457 0,08634191 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06093457 0,08629109 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06093457 0,08624033 ! axis specification GO:0009798 38 21 0,000 0,06093457 0,08618963 ! ovarian follicle development GO:0001541 35 21 0,000 0,06093457 0,08613899 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06093457 0,08608841 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06093457 0,08603789 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06093457 0,08598743 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06093457 0,08593703 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06093457 0,08588668 ! cell aging GO:0007569 44 21 0,000 0,06093457 0,0858364 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06093457 0,08578617 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06093457 0,085736 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06093457 0,0856859 ! cytolysis GO:0019835 24 21 0,000 0,06093457 0,08563585 ! vasodilation GO:0042311 39 21 0,000 0,06093457 0,08558585 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06093457 0,08553592 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06093457 0,08548604 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06093457 0,08543623 ! oogenesis GO:0048477 36 21 0,000 0,06093457 0,08538647 ! DNA modification GO:0006304 34 21 0,000 0,06093457 0,08533677 ! collagen fibril organization GO:0030199 59 21 0,000 0,06093457 0,08528712 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06093457 0,08523754 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06093457 0,08518801 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06093457 0,08513854 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06093457 0,08508913 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06093457 0,08503977 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06093457 0,08499047 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06093457 0,08494123 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06093457 0,08489205 ! collagen catabolic process GO:0030574 28 21 0,000 0,06093457 0,08484292 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06093457 0,08479385 ! gut development GO:0048565 39 21 0,000 0,06093457 0,08474484 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06374278 0,08859915 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06374278 0,08854799 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06374278 0,0884969 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06374278 0,08844586 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06374278 0,08839488 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06374278 0,08834396 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06374278 0,0882931 ! regeneration GO:0031099 41 22 0,000 0,06374278 0,0882423 ! keratinization GO:0031424 28 22 0,000 0,06374278 0,08819156 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06374278 0,08814087 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06374278 0,08809025 ! sensory perception of taste GO:0050909 28 22 0,000 0,06374278 0,08803968 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,06374278 0,08798917 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06374278 0,08793872 ! vacuolar transport GO:0007034 36 22 0,000 0,06374278 0,08788832 ! lysosome organization GO:0007040 41 22 0,000 0,06374278 0,08783798 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06374278 0,0877877 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06374278 0,08773748 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06374278 0,08768732 ! fucose metabolic process GO:0006004 39 22 0,000 0,06374278 0,08763721 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06374278 0,08758716 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06374278 0,08753717 ! ureteric bud development GO:0001657 43 22 0,000 0,06374278 0,08748723 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06374278 0,08743735 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06374278 0,08738753 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06374278 0,08733777 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06374278 0,08728806 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06374278 0,08723841 ! sarcomere organization GO:0045214 30 22 0,000 0,06374278 0,08718881 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,06374278 0,08713927 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06374278 0,08708979 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06374278 0,08704036 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06374278 0,08699099 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06374278 0,08694168 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06374278 0,08689242 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06654268 0,09065781 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06654268 0,0906065 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06654268 0,09055526 ! gluconeogenesis GO:0006094 33 23 0,000 0,06654268 0,09050407 ! viral genome replication GO:0019079 41 23 0,000 0,06654268 0,09045293 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06654268 0,09040186 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06654268 0,09035084 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06654268 0,09029988 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06654268 0,09024898 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06654268 0,09019814 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06654268 0,09014735 ! visual behavior GO:0007632 42 23 0,000 0,06654268 0,09009662 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06654268 0,09004595 ! response to ethanol GO:0045471 46 23 0,000 0,06654268 0,08999533 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06654268 0,08994477 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06654268 0,08989427 ! peroxisome organization GO:0007031 37 23 0,000 0,06654268 0,08984382 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06654268 0,08979343 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06654268 0,0897431 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06654268 0,08969283 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06654268 0,08964261 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,06654268 0,08959244 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06654268 0,08954233 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06654268 0,08949228 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06654268 0,08944229 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06654268 0,08939235 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06654268 0,08934246 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06654268 0,08929263 ! fatty acid transport GO:0015908 44 23 0,000 0,06654268 0,08924286 ! platelet activation GO:0030168 37 23 0,000 0,06654268 0,08919314 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06654268 0,08914348 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06654268 0,08909387 ! hormone transport GO:0009914 40 23 0,000 0,06654268 0,08904432 ! cell-cell recognition GO:0009988 25 23 0,000 0,06654268 0,08899483 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06654268 0,08894538 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06654268 0,088896 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06654268 0,08884667 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06654268 0,08879739 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,06933431 0,09247136 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,06933431 0,09242013 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06933431 0,09236896 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06933431 0,09231784 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06933431 0,09226678 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06933431 0,09221578 ! vesicle docking GO:0048278 47 24 0,000 0,06933431 0,09216483 ! spinal cord development GO:0021510 47 24 0,000 0,06933431 0,09211394 ! vacuole organization GO:0007033 43 24 0,000 0,06933431 0,0920631 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06933431 0,09201232 ! digestive system process GO:0022600 39 24 0,000 0,06933431 0,0919616 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06933431 0,09191093 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06933431 0,09186032 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06933431 0,09180976 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06933431 0,09175926 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06933431 0,09170882 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,06933431 0,09165843 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06933431 0,0916081 ! membrane depolarization GO:0051899 39 24 0,000 0,06933431 0,09155782 ! pentose metabolic process GO:0019321 35 24 0,000 0,06933431 0,09150759 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06933431 0,09145742 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06933431 0,09140731 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06933431 0,09135725 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06933431 0,09130725 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06933431 0,0912573 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06933431 0,0912074 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06933431 0,09115756 ! regulation of amine transport GO:0051952 40 24 0,000 0,06933431 0,09110778 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07211768 0,0947135 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,07211768 0,09466183 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07211768 0,09461021 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07211768 0,09455865 ! phototransduction GO:0007602 33 25 0,000 0,07211768 0,09450715 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07211768 0,0944557 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,07211768 0,09440431 ! sperm motility GO:0030317 31 25 0,000 0,07211768 0,09435298 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07211768 0,0943017 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,07211768 0,09425048 ! chromosome condensation GO:0030261 45 25 0,000 0,07211768 0,09419931 ! response to starvation GO:0042594 42 25 0,000 0,07211768 0,0941482 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07211768 0,09409714 ! neural crest cell development GO:0014032 54 25 0,000 0,07211768 0,09404614 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07211768 0,09399519 ! negative regulation of cell development GO:0010721 73 25 0,000 0,07211768 0,0939443 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07211768 0,09389347 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07211768 0,09384269 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07211768 0,09379196 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,07211768 0,09374129 ! immunoglobulin production GO:0002377 55 25 0,000 0,07211768 0,09369067 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07211768 0,09364011 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07211768 0,0935896 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07211768 0,09353915 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,07211768 0,09348875 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07211768 0,09343841 ! telomere organization GO:0032200 43 25 0,000 0,07211768 0,09338812 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07211768 0,09333788 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07211768 0,0932877 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07489281 0,09682542 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07489281 0,09677342 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07489281 0,09672147 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07489281 0,09666958 ! initiation of viral infection GO:0019059 57 26 0,000 0,07489281 0,09661775 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07489281 0,09656597 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07489281 0,09651425 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07489281 0,09646258 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07489281 0,09641097 ! molting cycle process GO:0022404 50 26 0,000 0,07489281 0,09635941 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07489281 0,09630791 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07489281 0,09625647 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07489281 0,09620508 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07489281 0,09615374 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,07489281 0,09610246 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07489281 0,09605123 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07489281 0,09600006 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07489281 0,09594894 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07489281 0,09589787 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07489281 0,09584686 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07489281 0,09579591 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07489281 0,09574501 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07489281 0,09569416 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07489281 0,09564337 ! blastocyst development GO:0001824 49 26 0,000 0,07489281 0,09559263 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07489281 0,09554194 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07489281 0,09549131 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07489281 0,09544073 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,07765974 0,09891442 ! neuron fate commitment GO:0048663 48 27 0,000 0,07765974 0,09886208 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,07765974 0,0988098 ! iron ion transport GO:0006826 59 27 0,000 0,07765974 0,09875758 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07765974 0,09870541 ! protein amino acid acylation GO:0043543 55 27 0,000 0,07765974 0,09865329 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07765974 0,09860123 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07765974 0,09854923 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07765974 0,09849728 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,07765974 0,09844538 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07765974 0,09839354 ! autophagy GO:0006914 41 27 0,000 0,07765974 0,09834176 ! male gonad development GO:0008584 44 27 0,000 0,07765974 0,09829002 ! response to toxin GO:0009636 47 27 0,000 0,07765974 0,09823835 ! primary neural tube formation GO:0014020 51 27 0,000 0,07765974 0,09818672 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07765974 0,09813516 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07765974 0,09808364 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07765974 0,09803218 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07765974 0,09798077 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07765974 0,09792942 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07765974 0,09787812 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07765974 0,09782688 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08041849 0,10124902 ! circadian rhythm GO:0007623 50 28 0,000 0,08041849 0,10119606 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08041849 0,10114317 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08041849 0,10109032 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08041849 0,10103753 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08041849 0,1009848 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08041849 0,10093212 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08041849 0,1008795 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08041849 0,10082693 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08041849 0,10077441 ! synaptogenesis GO:0007416 42 28 0,000 0,08041849 0,10072195 ! lipid oxidation GO:0034440 43 28 0,000 0,08041849 0,10066955 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08041849 0,1006172 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08041849 0,1005649 ! translational initiation GO:0006413 65 29 0,000 0,08316907 0,10395054 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08316907 0,10389656 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08316907 0,10384265 ! regulation of pH GO:0006885 43 29 0,000 0,08316907 0,10378879 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08316907 0,10373498 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08316907 0,10368123 ! catechol metabolic process GO:0009712 54 29 0,000 0,08316907 0,10362754 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08316907 0,1035739 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08316907 0,10352032 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08316907 0,10346679 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08316907 0,10341332 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08316907 0,10335991 ! cell fate determination GO:0001709 60 29 0,000 0,08316907 0,10330655 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08316907 0,10325324 ! detection of light stimulus GO:0009583 38 29 0,000 0,08316907 0,10319999 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,08316907 0,10314679 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08316907 0,10309365 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08316907 0,10304057 ! regulation of coagulation GO:0050818 46 29 0,000 0,08316907 0,10298754 ! phenol metabolic process GO:0018958 55 30 0,000 0,08591152 0,10632876 ! zinc ion transport GO:0006829 45 30 0,000 0,08591152 0,10627409 ! membrane docking GO:0022406 61 30 0,000 0,08591152 0,10621948 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08591152 0,10616493 ! cell junction assembly GO:0034329 78 30 0,000 0,08591152 0,10611043 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08591152 0,10605598 ! acute-phase response GO:0006953 49 30 0,000 0,08591152 0,1060016 ! myofibril assembly GO:0030239 47 30 0,000 0,08591152 0,10594726 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08591152 0,10589299 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08591152 0,10583877 ! phospholipid transport GO:0015914 51 30 0,000 0,08591152 0,1057846 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08591152 0,10573049 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08591152 0,10567644 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08591152 0,10562244 ! eye morphogenesis GO:0048592 60 30 0,000 0,08591152 0,10556849 ! regulation of B cell activation GO:0050864 50 30 0,000 0,08591152 0,10551461 ! response to heat GO:0009408 50 30 0,000 0,08591152 0,10546077 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08864585 0,10876182 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,08864585 0,10870638 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08864585 0,10865101 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08864585 0,10859568 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,08864585 0,10854042 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08864585 0,10848521 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08864585 0,10843006 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08864585 0,10837496 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08864585 0,10831992 ! ovulation cycle process GO:0022602 49 31 0,000 0,08864585 0,10826494 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08864585 0,10821001 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08864585 0,10815513 ! peptide transport GO:0015833 55 31 0,000 0,08864585 0,10810032 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08864585 0,10804555 ! iron ion homeostasis GO:0055072 54 31 0,000 0,08864585 0,10799085 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08864585 0,1079362 ! natural killer cell activation GO:0030101 45 31 0,000 0,08864585 0,1078816 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08864585 0,10782706 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08864585 0,10777257 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08864585 0,10771814 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08864585 0,10766377 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0913721 0,11091891 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0913721 0,11086297 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0913721 0,11080709 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0913721 0,11075127 ! cholesterol transport GO:0030301 56 32 0,000 0,0913721 0,11069551 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0913721 0,1106398 ! spliceosome assembly GO:0000245 67 32 0,000 0,0913721 0,11058414 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0913721 0,11052854 ! metanephros development GO:0001656 74 32 0,000 0,0913721 0,110473 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0913721 0,11041752 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0913721 0,11036209 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0913721 0,11030671 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0913721 0,11025139 ! muscle cell development GO:0055001 49 32 0,000 0,0913721 0,11019613 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0913721 0,11014092 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0913721 0,11008577 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0913721 0,11003067 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0913721 0,10997563 ! ovulation cycle GO:0042698 51 32 0,000 0,0913721 0,10992064 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0913721 0,1098657 ! hindbrain development GO:0030902 61 32 0,000 0,0913721 0,10981083 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0913721 0,109756 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0913721 0,10970123 ! gene silencing GO:0016458 65 32 0,000 0,0913721 0,10964652 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,09409028 0,11285205 ! post-embryonic development GO:0009791 69 33 0,000 0,09409028 0,11279583 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,09409028 0,11273965 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09409028 0,11268353 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09409028 0,11262747 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09409028 0,11257147 ! sterol transport GO:0015918 57 33 0,000 0,09409028 0,11251552 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09409028 0,11245962 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09409028 0,11240378 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09409028 0,112348 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09409028 0,11229227 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,09680042 0,11546942 ! glial cell differentiation GO:0010001 63 34 0,000 0,09680042 0,1154122 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09680042 0,11535504 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09680042 0,11529793 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09680042 0,11524088 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09680042 0,11518389 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09680042 0,11512695 ! spermatid development GO:0007286 63 34 0,000 0,09680042 0,11507007 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09680042 0,11501324 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09680042 0,11495648 ! placenta development GO:0001890 53 34 0,000 0,09680042 0,11489976 ! regulation of muscle development GO:0048634 70 35 0,000 0,09950255 0,11804888 ! negative regulation of secretion GO:0051048 63 35 0,000 0,09950255 0,1179907 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,09950255 0,11793258 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,09950255 0,11787451 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,09950255 0,1178165 ! female gonad development GO:0008585 58 35 0,000 0,09950255 0,11775855 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,09950255 0,11770065 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,09950255 0,11764281 ! cytokine production GO:0001816 59 35 0,000 0,09950255 0,11758503 ! neural tube formation GO:0001841 67 35 0,000 0,09950255 0,11752731 ! vesicle localization GO:0051648 64 35 0,000 0,09950255 0,11746964 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10219668 0,12059107 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10219668 0,12053196 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10219668 0,12047291 ! cell junction organization GO:0034330 86 36 0,000 0,10219668 0,12041391 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10219668 0,12035497 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10219668 0,12029609 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,10219668 0,12023726 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10219668 0,12017849 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10219668 0,12011979 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10219668 0,12006113 ! aerobic respiration GO:0009060 55 36 0,000 0,10219668 0,12000254 ! embryonic organ development GO:0048568 57 36 0,000 0,10219668 0,119944 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10219668 0,11988552 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10488283 0,12297665 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10488283 0,12291675 ! meiosis I GO:0007127 65 37 0,000 0,10488283 0,12285691 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,10488283 0,12279713 ! sister chromatid segregation GO:0000819 58 37 0,000 0,10488283 0,1227374 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10488283 0,12267773 ! organic anion transport GO:0015711 68 37 0,000 0,10488283 0,12261812 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,10488283 0,12255857 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10488283 0,12249908 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,10488283 0,12243964 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10488283 0,12238026 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,10488283 0,12232094 ! pigment metabolic process GO:0042440 80 37 0,000 0,10488283 0,12226167 ! spermatid differentiation GO:0048515 66 37 0,000 0,10488283 0,12220247 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10756104 0,12526228 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10756104 0,12520168 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,10756104 0,12514113 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10756104 0,12508065 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,10756104 0,12502023 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,10756104 0,12495986 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,10756104 0,12489955 ! lipid homeostasis GO:0055088 67 38 0,000 0,10756104 0,1248393 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10756104 0,12477911 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,10756104 0,12471897 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,10756104 0,1246589 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,10756104 0,12459888 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,10756104 0,12453892 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,10756104 0,12447901 ! glucan metabolic process GO:0044042 62 38 0,000 0,10756104 0,12441917 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,11023133 0,1274467 ! learning GO:0007612 77 39 0,000 0,11023133 0,12738548 ! ear morphogenesis GO:0042471 60 39 0,000 0,11023133 0,12732433 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11023133 0,12726323 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11023133 0,12720219 ! segmentation GO:0035282 67 39 0,000 0,11023133 0,12714121 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11023133 0,12708029 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11023133 0,12701943 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11023133 0,12695863 ! RNA modification GO:0009451 57 39 0,000 0,11023133 0,12689788 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11023133 0,12683719 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11289371 0,12983856 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11289371 0,12977653 ! feeding behavior GO:0007631 59 40 0,000 0,11289371 0,12971455 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11289371 0,12965263 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11289371 0,12959078 ! cytokinesis GO:0000910 72 40 0,000 0,11289371 0,12952898 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11554822 0,13251144 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11554822 0,13244831 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,11554822 0,13238524 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,11554822 0,13232223 ! gliogenesis GO:0042063 88 41 0,000 0,11554822 0,13225928 ! T cell differentiation GO:0030217 81 41 0,000 0,11554822 0,13219639 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,11554822 0,13213356 ! female gamete generation GO:0007292 61 41 0,000 0,11554822 0,13207079 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,11554822 0,13200808 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,11819487 0,13496766 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,11819487 0,13490363 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,11819487 0,13483966 ! regulation of tube size GO:0035150 71 42 0,000 0,11819487 0,13477576 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,11819487 0,13471191 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,11819487 0,13464813 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,11819487 0,13458441 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,11819487 0,13452074 ! neuron migration GO:0001764 79 42 0,000 0,11819487 0,13445714 ! regulation of protein secretion GO:0050708 71 42 0,000 0,11819487 0,1343936 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,11819487 0,13433011 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12083369 0,13726433 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12083369 0,13719955 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12083369 0,13713483 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12083369 0,13707018 ! glucose transport GO:0015758 65 43 0,000 0,12083369 0,13700558 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12083369 0,13694105 ! neural tube development GO:0021915 77 43 0,000 0,12083369 0,13687658 ! striated muscle contraction GO:0006941 77 43 0,000 0,12083369 0,13681216 ! phagocytosis GO:0006909 90 43 0,000 0,12083369 0,13674781 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12083369 0,13668352 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12346469 0,13959401 ! hexose transport GO:0008645 67 44 0,000 0,12346469 0,13952844 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12346469 0,13946294 ! male sex differentiation GO:0046661 76 44 0,000 0,12346469 0,13939749 ! double-strand break repair GO:0006302 81 44 0,000 0,12346469 0,13933211 ! biopolymer methylation GO:0043414 84 44 0,000 0,12346469 0,13926679 ! B cell differentiation GO:0030183 107 44 0,000 0,12346469 0,13920153 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12346469 0,13913633 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,12346469 0,13907119 ! developmental growth GO:0048589 82 44 0,000 0,12346469 0,13900611 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,12608792 0,14189314 ! glycolysis GO:0006096 65 45 0,000 0,12608792 0,1418268 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,12608792 0,14176053 ! leukocyte migration GO:0050900 68 45 0,000 0,12608792 0,14169432 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,12608792 0,14162816 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,12608792 0,14156208 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,12608792 0,14149605 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,12608792 0,14143008 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,12608792 0,14136418 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,12608792 0,14129834 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,12608792 0,14123256 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,12608792 0,14116684 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,12870338 0,14402806 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,12870338 0,1439611 ! pigmentation GO:0043473 100 46 0,000 0,12870338 0,1438942 ! positive regulation of defense response GO:0031349 76 47 0,000 0,13131109 0,14674152 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,13131109 0,1466734 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13131109 0,14660533 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13131109 0,14653733 ! JNK cascade GO:0007254 91 47 0,000 0,13131109 0,1464694 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13131109 0,14640153 ! methylation GO:0032259 90 47 0,000 0,13131109 0,14633372 ! protein homooligomerization GO:0051260 76 47 0,000 0,13131109 0,14626597 ! mitochondrial transport GO:0006839 82 48 0,000 0,13391109 0,14909306 ! Notch signaling pathway GO:0007219 96 48 0,000 0,13391109 0,1490241 ! cellular component disassembly GO:0022411 86 48 0,000 0,13391109 0,1489552 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,13391109 0,14888637 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,13391109 0,1488176 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,13391109 0,14874889 ! activation of caspase activity GO:0006919 84 48 0,000 0,13391109 0,14868025 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,13391109 0,14861167 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,13391109 0,14854315 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,1365034 0,15134893 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,1365034 0,15127922 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,1365034 0,15120957 ! regulation of ion transport GO:0043269 77 49 0,000 0,1365034 0,15113998 ! peptide metabolic process GO:0006518 76 49 0,000 0,1365034 0,15107046 ! response to temperature stimulus GO:0009266 76 49 0,000 0,1365034 0,151001 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,1365034 0,15093161 ! endocrine system development GO:0035270 104 49 0,000 0,1365034 0,15086228 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,1365034 0,15079301 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,1365034 0,15072381 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,1365034 0,15065467 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,1365034 0,15058559 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,13908803 0,15336655 ! neuromuscular process GO:0050905 99 50 0,000 0,13908803 0,15329629 ! regulation of ossification GO:0030278 117 50 0,000 0,13908803 0,1532261 ! inner ear development GO:0048839 79 50 0,000 0,13908803 0,15315597 ! histone modification GO:0016570 91 50 0,000 0,13908803 0,15308591 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,13908803 0,15301591 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,13908803 0,15294598 ! positive regulation of binding GO:0051099 78 51 0,000 0,14166501 0,15570855 ! viral infectious cycle GO:0019058 99 51 0,000 0,14166501 0,15563745 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,14166501 0,15556642 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,14166501 0,15549545 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,14166501 0,15542454 ! excretion GO:0007588 83 51 0,000 0,14166501 0,1553537 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,14166501 0,15528292 ! chromatin remodeling GO:0006338 109 51 0,000 0,14166501 0,15521221 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,14166501 0,15514156 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,14166501 0,15507098 ! vesicle organization GO:0016050 107 51 0,000 0,14166501 0,15500046 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,14166501 0,15493001 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,14423436 0,15766828 ! membrane fusion GO:0006944 110 52 0,000 0,14423436 0,15759668 ! covalent chromatin modification GO:0016569 101 52 0,000 0,14423436 0,15752514 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,14423436 0,15745367 ! amino acid activation GO:0043038 92 52 0,000 0,14423436 0,15738226 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,14423436 0,15731092 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,14679611 0,16003237 ! RNA catabolic process GO:0006401 93 53 0,000 0,14679611 0,15995989 ! regulation of translational initiation GO:0006446 82 53 0,000 0,14679611 0,15988748 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,14679611 0,15981513 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,14679611 0,15974285 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,14679611 0,15967063 ! cell maturation GO:0048469 100 53 0,000 0,14679611 0,15959848 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,14679611 0,1595264 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,14679611 0,15945438 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,14935027 0,16215558 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,14935027 0,16208243 ! cell recognition GO:0008037 85 54 0,000 0,14935027 0,16200936 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,14935027 0,16193635 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,14935027 0,1618634 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,14935027 0,16179053 ! chloride transport GO:0006821 90 55 0,000 0,15189687 0,16447519 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,15189687 0,16440121 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,15189687 0,16432728 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,15189687 0,16425343 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,15189687 0,16417964 ! aging GO:0007568 103 55 0,000 0,15189687 0,16410592 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,15189687 0,16403226 ! RNA elongation GO:0006354 79 55 0,000 0,15189687 0,16395867 ! nuclear export GO:0051168 97 55 0,000 0,15189687 0,16388515 ! regulation of actin filament length GO:0030832 105 56 0,000 0,15443594 0,16654992 ! sensory perception of smell GO:0007608 80 56 0,000 0,15443594 0,1664753 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,15443594 0,16640074 ! proton transport GO:0015992 94 56 0,000 0,15443594 0,16632626 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,15443594 0,16625184 ! hydrogen transport GO:0006818 97 58 0,000 0,15949153 0,17161745 ! regulation of endocytosis GO:0030100 91 58 0,000 0,15949153 0,17154073 ! adult behavior GO:0030534 99 58 0,000 0,15949153 0,17146408 ! regulation of cellular component size GO:0032535 109 59 0,000 0,16200811 0,17409178 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,16200811 0,17401406 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,16200811 0,17393641 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,16200811 0,17385883 ! DNA catabolic process GO:0006308 86 59 0,000 0,16200811 0,17378132 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,16200811 0,17370388 ! establishment of organelle localization GO:0051656 109 59 0,000 0,16200811 0,17362651 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,16451723 0,17623707 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,16451723 0,17615864 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,16451723 0,17608027 ! regulation of heart contraction GO:0008016 110 60 0,000 0,16451723 0,17600198 ! camera-type eye development GO:0043010 116 60 0,000 0,16451723 0,17592376 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,16451723 0,17584561 ! kidney development GO:0001822 122 60 0,000 0,16451723 0,17576752 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,16701893 0,17836109 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,16701893 0,17828196 ! tRNA processing GO:0008033 89 61 0,000 0,16701893 0,1782029 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,16701893 0,17812391 ! ear development GO:0043583 103 62 0,000 0,16951321 0,18070394 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,16951321 0,18062391 ! gonad development GO:0008406 98 62 0,000 0,16951321 0,18054395 ! regulation of mitosis GO:0007088 105 63 0,000 0,17200011 0,18311163 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,17200011 0,18303064 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,17200011 0,18294972 ! detection of external stimulus GO:0009581 91 63 0,000 0,17200011 0,18286888 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,17200011 0,18278811 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,17447965 0,1853413 ! cell redox homeostasis GO:0045454 102 64 0,000 0,17447965 0,18525951 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,17447965 0,18517779 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,17447965 0,18509614 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,17447965 0,18501456 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,17695184 0,18755336 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,17695184 0,18747078 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,17695184 0,18738826 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,17695184 0,18730582 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,17695184 0,18722346 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,17941672 0,18974796 ! extracellular matrix organization GO:0030198 133 66 0,000 0,17941672 0,1896646 ! secondary metabolic process GO:0019748 116 66 0,000 0,17941672 0,1895813 ! developmental maturation GO:0021700 116 66 0,000 0,17941672 0,18949808 ! cell projection assembly GO:0030031 120 66 0,000 0,17941672 0,18941493 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,18187429 0,19192524 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,18187429 0,1918411 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,18187429 0,19175703 ! chromosome segregation GO:0007059 113 67 0,000 0,18187429 0,19167303 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,18187429 0,19158911 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,18187429 0,19150527 ! hexose catabolic process GO:0019320 104 67 0,000 0,18187429 0,1914215 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,18187429 0,1913378 ! activation of immune response GO:0002253 105 67 0,000 0,18187429 0,19125417 ! amino acid transport GO:0006865 125 68 0,000 0,18432458 0,19374615 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,18432458 0,19366155 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,18432458 0,19357702 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,18432458 0,19349256 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,18432458 0,19340817 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,18432458 0,19332386 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,18676762 0,19580082 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,18676762 0,19571554 ! urogenital system development GO:0001655 137 69 0,000 0,18676762 0,19563034 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,18676762 0,19554521 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,18676762 0,19546015 ! antigen processing and presentation GO:0019882 104 69 0,000 0,18676762 0,19537517 ! appendage morphogenesis GO:0035107 135 70 0,000 0,18920342 0,19783721 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,191632 0,20028957 ! reproductive structure development GO:0048608 113 71 0,000 0,191632 0,2002026 ! appendage development GO:0048736 136 71 0,000 0,191632 0,20011571 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,191632 0,20002889 ! B cell activation GO:0042113 160 71 0,000 0,191632 0,19994215 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,191632 0,19985548 ! regulation of immune effector process GO:0002697 137 71 0,000 0,191632 0,19976889 ! acute inflammatory response GO:0002526 113 72 0,000 0,19405339 0,20220549 ! regulation of caspase activity GO:0043281 122 72 0,000 0,19405339 0,20211795 ! carbohydrate transport GO:0008643 110 72 0,000 0,19405339 0,20203049 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,19405339 0,20194311 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,19405339 0,2018558 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,19405339 0,20176857 ! learning or memory GO:0007611 147 73 0,000 0,19646761 0,20419053 ! regulation of blood pressure GO:0008217 125 73 0,000 0,19646761 0,20410236 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,19646761 0,20401427 ! fertilization GO:0009566 90 73 0,000 0,19646761 0,20392626 ! transition metal ion transport GO:0000041 126 74 0,000 0,19887468 0,2063357 ! neurotransmitter transport GO:0006836 123 74 0,000 0,19887468 0,20624676 ! meiosis GO:0007126 121 74 0,000 0,19887468 0,2061579 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,19887468 0,20606911 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,19887468 0,2059804 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,19887468 0,20589177 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,19887468 0,20580322 ! eye development GO:0001654 143 74 0,000 0,19887468 0,20571474 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,20127462 0,20810775 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,20127462 0,20801835 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,20127462 0,20792904 ! meiotic cell cycle GO:0051321 122 75 0,000 0,20127462 0,2078398 ! rhythmic process GO:0048511 128 75 0,000 0,20127462 0,20775063 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,20127462 0,20766155 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,20366744 0,21004023 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,20366744 0,20995024 ! defense response to bacterium GO:0042742 89 76 0,000 0,20366744 0,20986033 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,20366744 0,20977049 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,20366744 0,20968073 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,20605318 0,21204617 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,20605318 0,21195551 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,20605318 0,21186493 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,20605318 0,21177443 ! blood coagulation GO:0007596 146 78 0,000 0,20843185 0,21412768 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,20843185 0,21403629 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,20843185 0,21394498 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,20843185 0,21385374 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,21080347 0,21619486 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,21080347 0,21610275 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,21080347 0,21601071 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,21080347 0,21591875 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,21080347 0,21582687 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,21080347 0,21573507 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,21316806 0,21806223 ! protein import into nucleus GO:0006606 158 80 0,000 0,21316806 0,21796955 ! inorganic anion transport GO:0015698 138 80 0,000 0,21316806 0,21787696 ! T cell activation GO:0042110 168 81 0,000 0,21552565 0,22019309 ! digestion GO:0007586 112 81 0,000 0,21552565 0,22009963 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,21552565 0,22000624 ! nuclear import GO:0051170 161 81 0,000 0,21552565 0,21991294 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,21552565 0,21981972 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,21787625 0,22212299 ! response to drug GO:0042493 143 82 0,000 0,21787625 0,22202891 ! response to nutrient GO:0007584 125 82 0,000 0,21787625 0,22193491 ! hemostasis GO:0007599 158 84 0,000 0,22255658 0,22660649 ! regulation of ligase activity GO:0051340 142 84 0,000 0,22255658 0,22651063 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,22255658 0,22641486 ! nucleosome assembly GO:0006334 122 85 0,000 0,22488635 0,22868832 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,22488635 0,2285917 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,22488635 0,22849517 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,22720921 0,23075786 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,22720921 0,23066049 ! chromatin assembly GO:0031497 124 86 0,000 0,22720921 0,23056321 ! tube morphogenesis GO:0035239 176 86 0,000 0,22720921 0,23046601 ! mitochondrion organization GO:0007005 148 86 0,000 0,22720921 0,23036889 ! alcohol catabolic process GO:0046164 130 86 0,000 0,22720921 0,23027185 ! amine transport GO:0015837 155 86 0,000 0,22720921 0,23017489 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,22952519 0,23242324 ! protein localization in nucleus GO:0034504 176 87 0,000 0,22952519 0,23232546 ! cellular respiration GO:0045333 135 88 0,000 0,23183431 0,23456406 ! regulation of neurological system process GO:0031644 148 88 0,000 0,23183431 0,23446547 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,23183431 0,23436695 ! cellular defense response GO:0006968 114 89 0,000 0,23413658 0,23659496 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,23643203 0,23881421 ! sex differentiation GO:0007548 145 90 0,000 0,23643203 0,238714 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,23643203 0,23861387 ! sterol metabolic process GO:0016125 152 91 0,000 0,23872067 0,24082261 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,23872067 0,24072168 ! regulation of defense response GO:0031347 149 92 0,000 0,24100253 0,24292086 ! nucleosome organization GO:0034728 138 92 0,000 0,24100253 0,24281913 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,24100253 0,24271749 ! vitamin metabolic process GO:0006766 139 92 0,000 0,24100253 0,24261594 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,24327763 0,24480384 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,24327763 0,24470149 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,24554598 0,24687991 ! female pregnancy GO:0007565 164 94 0,000 0,24554598 0,24677679 ! transcription initiation GO:0006352 153 94 0,000 0,24554598 0,24667375 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,24780761 0,24884186 ! leukocyte differentiation GO:0002521 202 96 0,000 0,25006253 0,25100144 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,25006253 0,25089677 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,25006253 0,25079219 ! detection of stimulus GO:0051606 151 96 0,000 0,25006253 0,25068769 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,25231077 0,2528362 ! hormone metabolic process GO:0042445 157 97 0,000 0,25231077 0,25273094 ! response to virus GO:0009615 160 98 0,000 0,25455234 0,25487014 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,25455234 0,25476412 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,25455234 0,25465819 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,25678727 0,25678727