pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6571-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 3,000 1,508E-08 3,628E-05 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 7,000 4,842E-08 5,825E-05 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 7,000 6,799E-08 5,453E-05 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 7,000 6,799E-08 4,089E-05 ! positive regulation of ligase activity GO:0051351 124 77 7,000 1,158E-07 5,57E-05 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 7,000 1,417E-07 5,682E-05 ! regulation of ligase activity GO:0051340 142 84 7,000 2,293E-07 7,882E-05 ! apoptotic mitochondrial changes GO:0008637 41 20 4,000 3,15E-07 9,473E-05 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 6,000 7,789E-07 2,082E-04 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 1,288E-06 3,1E-04 ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 2,863E-06 6,262E-04 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 4,069E-06 8,159E-04 ! response to peptide hormone stimulus GO:0043434 122 61 5,000 6,409E-06 1,186E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 6,000 6,5E-06 1,117E-03 GO:0010498|proteasomal protein catabolic process, ! cell junction organization GO:0034330 86 36 4,000 6,948E-06 1,114E-03 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 7,985E-06 1,201E-03 ! deoxyribonucleoside metabolic process GO:0009120 8 6 2,000 8,094E-06 1,146E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 3,000 8,549E-06 1,143E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 5,000 1,11E-05 1,405E-03 ! negative regulation of ligase activity GO:0051352 112 68 5,000 1,21E-05 1,455E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! peptidyl-serine modification GO:0018209 43 20 3,000 1,338E-05 1,533E-03 ! B cell lineage commitment GO:0002326 21 7 2,000 1,409E-05 1,54E-03 ! T cell lineage commitment GO:0002360 16 7 2,000 1,409E-05 1,474E-03 ! deoxyribonucleotide metabolic process GO:0009262 32 22 3,000 1,996E-05 2,001E-03 ! ER overload response GO:0006983 12 8 2,000 2,241E-05 2,157E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,241E-05 2,074E-03 ! response to insulin stimulus GO:0032868 95 46 4,000 2,377E-05 2,119E-03 ! response to ethanol GO:0045471 46 23 3,000 2,402E-05 2,064E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 3,000 2,402E-05 1,993E-03 ! regulation of developmental growth GO:0048638 15 9 2,000 3,343E-05 2,681E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 3,343E-05 2,595E-03 ! response to drug GO:0042493 143 82 5,000 3,548E-05 2,667E-03 ! positive regulation of growth GO:0045927 90 52 4,000 4,347E-05 3,169E-03 ! mitochondrion organization GO:0007005 148 86 5,000 4,647E-05 3,288E-03 ! protein sumoylation GO:0016925 15 10 2,000 4,75E-05 3,265E-03 ! response to UV GO:0009411 104 53 4,000 4,77E-05 3,188E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 3,000 6,221E-05 4,045E-03 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 2,000 6,495E-05 4,112E-03 ! regulation of embryonic development GO:0045995 27 11 2,000 6,495E-05 4,007E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 6,794E-05 4,086E-03 ! cell junction assembly GO:0034329 78 30 3,000 7,136E-05 4,188E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 3,000 7,136E-05 4,088E-03 ! regulation of membrane potential GO:0042391 164 93 5,000 7,214E-05 4,036E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 8,612E-05 4,709E-03 ! focal adhesion formation GO:0048041 35 12 2,000 8,612E-05 4,605E-03 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 2,000 8,612E-05 4,505E-03 ! T cell homeostasis GO:0043029 25 12 2,000 8,612E-05 4,409E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 8,702E-05 4,362E-03 ! regulation of homeostatic process GO:0032844 134 62 4,000 1,019E-04 5,002E-03 ! regulation of skeletal muscle fiber development GO:0048742 32 13 2,000 1,113E-04 5,358E-03 ! response to gamma radiation GO:0010332 28 14 2,000 1,409E-04 6,649E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 1,696E-04 7,846E-03 ! regulation of skeletal muscle tissue development GO:0048641 35 15 2,000 1,752E-04 7,953E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 1,752E-04 7,806E-03 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 2,000 1,752E-04 7,664E-03 ! lymphocyte homeostasis GO:0002260 30 15 2,000 1,752E-04 7,527E-03 ! learning GO:0007612 77 39 3,000 2,032E-04 8,577E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 2,144E-04 8,895E-03 ! cell-matrix adhesion GO:0007160 163 75 4,000 2,511E-04 0,01024133 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 2,000 2,59E-04 0,01038395 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of survival gene product expression GO:0045884 33 17 2,000 2,59E-04 0,01021372 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,59E-04 0,01004899 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 2,59E-04 9,889E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 3,09E-04 0,01161767 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 3,554E-04 0,01315526 ! cell-substrate adhesion GO:0031589 171 81 4,000 3,596E-04 0,01310725 ! regulation of postsynaptic membrane potential GO:0060078 32 19 2,000 3,65E-04 0,01310577 ! visual learning GO:0008542 36 19 2,000 3,65E-04 0,01291304 ! cellular pigmentation GO:0033059 36 19 2,000 3,65E-04 0,01272589 ! cell-cell junction organization GO:0045216 35 19 2,000 3,65E-04 0,01254409 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 3,806E-04 0,01289732 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 3,87E-04 0,01293169 ! pigmentation GO:0043473 100 46 3,000 3,87E-04 0,01275454 ! response to alkaloid GO:0043279 38 20 2,000 4,27E-04 0,01388329 ! cellular response to starvation GO:0009267 33 20 2,000 4,27E-04 0,01369818 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 4,27E-04 0,01351794 ! D-ribose metabolic process GO:0006014 29 20 2,000 4,27E-04 0,01334238 ! DNA-dependent DNA replication GO:0006261 74 49 3,000 4,937E-04 0,01522991 ! cell aging GO:0007569 44 21 2,000 4,954E-04 0,01508864 ! cytolysis GO:0019835 24 21 2,000 4,954E-04 0,01490003 ! gland development GO:0048732 206 88 4,000 5,27E-04 0,01565474 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,475E-04 0,01606421 ! lipoprotein particle clearance GO:0034381 10 5 1,000 5,475E-04 0,01587067 ! positive regulation of glycolysis GO:0045821 14 5 1,000 5,475E-04 0,01568173 ! anagen GO:0042640 6 5 1,000 5,475E-04 0,01549724 ! skeletal myofibril assembly GO:0014866 10 5 1,000 5,475E-04 0,01531704 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 5,475E-04 0,01514098 ! microvillus organization GO:0032528 7 5 1,000 5,475E-04 0,01496892 GO:0030033|microvillus assembly, ! response to food GO:0032094 6 5 1,000 5,475E-04 0,01480073 ! lipoprotein catabolic process GO:0042159 11 5 1,000 5,475E-04 0,01463628 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 5,475E-04 0,01447544 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 5,475E-04 0,0143181 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 1,000 5,475E-04 0,01416414 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 5,475E-04 0,01401346 ! meiotic chromosome segregation GO:0045132 7 5 1,000 5,475E-04 0,01386595 ! B cell homeostasis GO:0001782 13 5 1,000 5,475E-04 0,01372151 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 5,475E-04 0,01358005 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 5,475E-04 0,01344148 ! regulation of sensory perception GO:0051931 7 5 1,000 5,475E-04 0,01330571 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 5,475E-04 0,01317265 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 5,475E-04 0,01304223 GO:0022011|myelination in the peripheral nervous system, ! glutamate signaling pathway GO:0007215 41 22 2,000 5,705E-04 0,01345716 ! renal system process GO:0003014 41 22 2,000 5,705E-04 0,01332651 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 5,705E-04 0,01319837 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 5,705E-04 0,01307267 ! synapse organization GO:0050808 85 52 3,000 6,199E-04 0,01407151 ! visual behavior GO:0007632 42 23 2,000 6,525E-04 0,01467154 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 2,000 6,525E-04 0,01453569 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 7,416E-04 0,01636945 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 7,416E-04 0,01622063 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 7,416E-04 0,0160745 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 7,416E-04 0,01593098 ! membrane depolarization GO:0051899 39 24 2,000 7,416E-04 0,01579 ! pentose metabolic process GO:0019321 35 24 2,000 7,416E-04 0,01565149 ! leukocyte homeostasis GO:0001776 44 24 2,000 7,416E-04 0,01551539 ! protein tetramerization GO:0051262 52 24 2,000 7,416E-04 0,01538163 ! regulation of multicellular organism growth GO:0040014 85 55 3,000 7,675E-04 0,0157823 ! regulation of respiratory gaseous exchange GO:0043576 8 6 1,000 8,172E-04 0,01666238 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 8,172E-04 0,01652236 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 8,172E-04 0,01638467 ! male sex determination GO:0030238 15 6 1,000 8,172E-04 0,01624926 ! establishment of spindle localization GO:0051293 12 6 1,000 8,172E-04 0,01611607 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 14 6 1,000 8,172E-04 0,01598505 ! astrocyte development GO:0014002 15 6 1,000 8,172E-04 0,01585614 ! hair follicle maturation GO:0048820 7 6 1,000 8,172E-04 0,01572929 ! Schwann cell development GO:0014044 15 6 1,000 8,172E-04 0,01560445 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 8,172E-04 0,01548158 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 8,172E-04 0,01536063 ! triglyceride catabolic process GO:0019433 10 6 1,000 8,172E-04 0,01524156 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 8,172E-04 0,01512432 ! myelination GO:0042552 45 25 2,000 8,381E-04 0,01539275 ! response to starvation GO:0042594 42 25 2,000 8,381E-04 0,01527614 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 8,381E-04 0,01516128 ! cellular response to nutrient levels GO:0031669 41 25 2,000 8,381E-04 0,01504814 ! positive regulation of cell migration GO:0030335 126 57 3,000 8,786E-04 0,01565854 ! molting cycle process GO:0022404 50 26 2,000 9,422E-04 0,01666882 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 9,422E-04 0,01654715 GO:0045936|negative regulation of phosphate metabolic process, ! cell cycle arrest GO:0007050 213 100 4,000 9,422E-04 0,01642764 ! integrin-mediated signaling pathway GO:0007229 135 59 3,000 1,001E-03 0,01731975 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,054E-03 0,01811673 ! mitochondrial membrane organization GO:0007006 57 27 2,000 1,054E-03 0,01798824 ! regulation of chromosome organization GO:0033044 42 27 2,000 1,054E-03 0,01786157 ! regulation of helicase activity GO:0051095 15 7 1,000 1,138E-03 0,01915433 ! prostate gland development GO:0030850 13 7 1,000 1,138E-03 0,01902131 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 1,138E-03 0,01889013 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,138E-03 0,01876075 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,138E-03 0,01863312 ! mRNA stabilization GO:0048255 18 7 1,000 1,138E-03 0,01850722 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,138E-03 0,01838301 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 1,000 1,138E-03 0,01826046 ! glycerol ether catabolic process GO:0044269 12 7 1,000 1,138E-03 0,01813953 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 1,000 1,138E-03 0,01802019 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,138E-03 0,01790241 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,138E-03 0,01778616 ! response to tumor cell GO:0002347 13 7 1,000 1,138E-03 0,01767141 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,138E-03 0,01755814 ! peptidyl-threonine modification GO:0018210 25 7 1,000 1,138E-03 0,0174463 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 1,138E-03 0,01733588 ! endosome to lysosome transport GO:0008333 11 7 1,000 1,138E-03 0,01722685 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,174E-03 0,01765706 ! synaptogenesis GO:0007416 42 28 2,000 1,174E-03 0,01754739 ! regulation of mitosis GO:0007088 105 63 3,000 1,279E-03 0,01900267 GO:0051783|regulation of nuclear division, ! complement activation, classical pathway GO:0006958 48 29 2,000 1,303E-03 0,01922599 ! response to organic cyclic substance GO:0014070 55 29 2,000 1,303E-03 0,01910875 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 1,303E-03 0,01899294 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,357E-03 0,01966652 ! ensheathment of neurons GO:0007272 57 30 2,000 1,439E-03 0,02073631 GO:0008366|axon ensheathment, ! response to heat GO:0009408 50 30 2,000 1,439E-03 0,02061288 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,51E-03 0,02150365 ! neutral lipid catabolic process GO:0046461 13 8 1,000 1,51E-03 0,02137716 ! oligopeptide transport GO:0006857 15 8 1,000 1,51E-03 0,02125215 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,51E-03 0,02112859 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,51E-03 0,02100646 ! glycerolipid catabolic process GO:0046503 13 8 1,000 1,51E-03 0,02088573 ! pigment granule organization GO:0048753 16 8 1,000 1,51E-03 0,02076638 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,51E-03 0,02064839 ! astrocyte differentiation GO:0048708 18 8 1,000 1,51E-03 0,02053173 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 1,51E-03 0,02041639 GO:0006559|L-phenylalanine catabolic process, ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,51E-03 0,02030233 ! melanin metabolic process GO:0006582 15 8 1,000 1,51E-03 0,02018954 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,51E-03 0,02007799 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,51E-03 0,01996768 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,51E-03 0,01985856 ! response to UV-B GO:0010224 16 8 1,000 1,51E-03 0,01975064 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,51E-03 0,01964388 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,51E-03 0,01953826 ! actin filament organization GO:0007015 148 66 3,000 1,521E-03 0,01957429 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 2,000 1,585E-03 0,0202819 ! negative regulation of cell growth GO:0030308 132 67 3,000 1,609E-03 0,02047761 ! lung development GO:0030324 144 67 3,000 1,609E-03 0,02036983 ! adaptive immune response GO:0002250 119 67 3,000 1,609E-03 0,02026318 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 3,000 1,609E-03 0,02015765 ! spindle organization GO:0007051 46 32 2,000 1,739E-03 0,02168089 ! response to ionizing radiation GO:0010212 65 32 2,000 1,739E-03 0,02156913 ! peripheral nervous system development GO:0007422 64 32 2,000 1,739E-03 0,02145852 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,739E-03 0,02134904 ! urogenital system development GO:0001655 137 69 3,000 1,793E-03 0,02190279 ! respiratory tube development GO:0030323 150 70 3,000 1,891E-03 0,02297924 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,932E-03 0,02336408 ! cell proliferation in forebrain GO:0021846 15 9 1,000 1,932E-03 0,02324726 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,932E-03 0,0231316 ! regulation of glycolysis GO:0006110 21 9 1,000 1,932E-03 0,02301709 ! cerebral cortex cell migration GO:0021795 15 9 1,000 1,932E-03 0,02290371 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 1,932E-03 0,02279143 ! microtubule bundle formation GO:0001578 21 9 1,000 1,932E-03 0,02268026 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,932E-03 0,02257016 ! T cell selection GO:0045058 23 9 1,000 1,932E-03 0,02246112 ! intestinal cholesterol absorption GO:0030299 16 9 1,000 1,932E-03 0,02235314 ! behavioral fear response GO:0001662 22 9 1,000 1,932E-03 0,02224618 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,932E-03 0,02214025 ! protein heterooligomerization GO:0051291 16 9 1,000 1,932E-03 0,02203532 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,932E-03 0,02193138 ! nucleoside diphosphate metabolic process GO:0009132 13 9 1,000 1,932E-03 0,02182842 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,932E-03 0,02172641 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,932E-03 0,02162536 ! regulation of synaptogenesis GO:0051963 15 9 1,000 1,932E-03 0,02152524 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,932E-03 0,02142605 ! humoral immune response GO:0006959 109 71 3,000 1,992E-03 0,0219892 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 2,075E-03 0,02279998 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 2,000 2,075E-03 0,02269634 ! respiratory system development GO:0060541 153 72 3,000 2,097E-03 0,02283386 ! learning or memory GO:0007611 147 73 3,000 2,206E-03 0,02390976 ! regulation of muscle development GO:0048634 70 35 2,000 2,257E-03 0,02435624 ! regulation of microtubule-based process GO:0032886 78 35 2,000 2,257E-03 0,0242475 ! meiosis GO:0007126 121 74 3,000 2,319E-03 0,02479493 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,404E-03 0,02558958 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,404E-03 0,02547685 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 2,404E-03 0,02536511 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 2,404E-03 0,02525434 ! lung alveolus development GO:0048286 26 10 1,000 2,404E-03 0,02514454 ! glucan biosynthetic process GO:0009250 14 10 1,000 2,404E-03 0,02503569 GO:0005978|glycogen biosynthetic process, ! B cell proliferation GO:0042100 18 10 1,000 2,404E-03 0,02492778 ! epithelial cell development GO:0002064 20 10 1,000 2,404E-03 0,02482079 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,404E-03 0,02471472 ! regulation of bone resorption GO:0045124 25 10 1,000 2,404E-03 0,02460955 ! alpha-beta T cell activation GO:0046631 23 10 1,000 2,404E-03 0,02450527 ! apical protein localization GO:0045176 15 10 1,000 2,404E-03 0,02440188 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 2,404E-03 0,02429935 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,404E-03 0,02419768 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 2,404E-03 0,02409685 ! response to nicotine GO:0035094 20 10 1,000 2,404E-03 0,02399687 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,404E-03 0,02389771 ! meiotic cell cycle GO:0051321 122 75 3,000 2,435E-03 0,0241116 ! meiosis I GO:0007127 65 37 2,000 2,651E-03 0,02613823 ! glycogen metabolic process GO:0005977 61 37 2,000 2,651E-03 0,02603154 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 2,000 2,862E-03 0,02799416 GO:0006956|complement activation, ! carbohydrate homeostasis GO:0033500 53 38 2,000 2,862E-03 0,02788082 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 62 38 2,000 2,862E-03 0,0277684 GO:0006073|cellular glucan metabolic process, ! telencephalon cell migration GO:0022029 20 11 1,000 2,923E-03 0,02824772 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,923E-03 0,02813473 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,923E-03 0,02802264 ! blood vessel remodeling GO:0001974 29 11 1,000 2,923E-03 0,02791144 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,923E-03 0,02780112 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,923E-03 0,02769167 ! regulation of intracellular pH GO:0051453 19 11 1,000 2,923E-03 0,02758307 ! lipid digestion GO:0044241 18 11 1,000 2,923E-03 0,02747532 ! negative regulation of ossification GO:0030279 26 11 1,000 2,923E-03 0,02736842 ! DNA methylation GO:0006306 19 11 1,000 2,923E-03 0,02726234 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,923E-03 0,02715708 ! oocyte differentiation GO:0009994 18 11 1,000 2,923E-03 0,02705263 ! thymus development GO:0048538 27 11 1,000 2,923E-03 0,02694898 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 2,923E-03 0,02684612 ! regulation of synapse organization GO:0050807 17 11 1,000 2,923E-03 0,02674404 ! regulation of action potential in neuron GO:0019228 73 39 2,000 3,084E-03 0,02810494 ! response to hypoxia GO:0001666 171 81 3,000 3,22E-03 0,02923157 ! regulation of neuron differentiation GO:0045664 167 81 3,000 3,22E-03 0,02912168 ! virus-host interaction GO:0019048 29 12 1,000 3,491E-03 0,03145684 ! regulation of B cell proliferation GO:0030888 20 12 1,000 3,491E-03 0,03133947 ! cartilage condensation GO:0001502 20 12 1,000 3,491E-03 0,03122296 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 3,491E-03 0,03110732 GO:0050927|positive regulation of positive chemotaxis, ! drug transport GO:0015893 16 12 1,000 3,491E-03 0,03099253 ! tyrosine metabolic process GO:0006570 16 12 1,000 3,491E-03 0,03087859 ! forebrain cell migration GO:0021885 21 12 1,000 3,491E-03 0,03076548 ! asymmetric protein localization GO:0008105 20 12 1,000 3,491E-03 0,0306532 ! fear response GO:0042596 26 12 1,000 3,491E-03 0,03054173 ! synaptic vesicle exocytosis GO:0016079 19 12 1,000 3,491E-03 0,03043108 ! histone acetylation GO:0016573 26 12 1,000 3,491E-03 0,03032122 ! gland morphogenesis GO:0022612 29 12 1,000 3,491E-03 0,03021215 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,491E-03 0,03010386 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 3,491E-03 0,02999635 ! spleen development GO:0048536 22 12 1,000 3,491E-03 0,0298896 ! digestive tract morphogenesis GO:0048546 26 12 1,000 3,491E-03 0,02978361 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 3,491E-03 0,02967836 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 3,491E-03 0,02957386 ! regulation of synapse structure and activity GO:0050803 18 12 1,000 3,491E-03 0,02947009 ! response to oxygen levels GO:0070482 176 83 3,000 3,515E-03 0,02957193 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 2,000 3,558E-03 0,02982701 ! T cell differentiation GO:0030217 81 41 2,000 3,558E-03 0,02972345 ! negative regulation of growth GO:0045926 155 84 3,000 3,67E-03 0,0305511 ! response to reactive oxygen species GO:0000302 67 42 2,000 3,811E-03 0,03161571 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 3,811E-03 0,03150706 ! epithelial cell differentiation GO:0030855 79 43 2,000 4,074E-03 0,03357005 ! energy reserve metabolic process GO:0006112 74 43 2,000 4,074E-03 0,03345547 ! glucose transport GO:0015758 65 43 2,000 4,074E-03 0,03334168 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 4,105E-03 0,03348256 ! Golgi organization GO:0007030 24 13 1,000 4,105E-03 0,03336944 ! cell-cell junction assembly GO:0007043 27 13 1,000 4,105E-03 0,03325709 ! response to X-ray GO:0010165 25 13 1,000 4,105E-03 0,03314549 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 4,105E-03 0,03303463 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 4,105E-03 0,03292452 ! regulation of cellular pH GO:0030641 22 13 1,000 4,105E-03 0,03281513 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 4,105E-03 0,03270647 ! regulation of mRNA stability GO:0043488 31 13 1,000 4,105E-03 0,03259853 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 4,105E-03 0,0324913 ! regulation of neurological system process GO:0031644 148 88 3,000 4,334E-03 0,03418638 ! hexose transport GO:0008645 67 44 2,000 4,348E-03 0,03419074 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 107 44 2,000 4,348E-03 0,03407937 ! developmental growth GO:0048589 82 44 2,000 4,348E-03 0,03396872 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 4,512E-03 0,0351284 ! regulation of cell adhesion GO:0030155 212 89 3,000 4,512E-03 0,03501508 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 4,634E-03 0,03584759 ! regulation of cell cycle process GO:0010564 149 90 3,000 4,694E-03 0,03619927 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,766E-03 0,036636 ! hair follicle morphogenesis GO:0031069 26 14 1,000 4,766E-03 0,03651933 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 4,766E-03 0,03640339 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 4,766E-03 0,03628819 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 4,766E-03 0,03617372 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 4,766E-03 0,03605996 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 4,766E-03 0,03594692 ! intestinal absorption GO:0050892 25 14 1,000 4,766E-03 0,03583459 ! regulation of RNA stability GO:0043487 32 14 1,000 4,766E-03 0,03572295 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 4,93E-03 0,0368368 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,93E-03 0,03672276 ! regulation of JNK cascade GO:0046328 94 47 2,000 5,237E-03 0,03889259 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 5,272E-03 0,03902794 ! pituitary gland development GO:0021983 29 15 1,000 5,472E-03 0,04038768 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 5,472E-03 0,04026417 ! G1/S transition checkpoint GO:0031575 40 15 1,000 5,472E-03 0,04014142 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 5,472E-03 0,04001941 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 5,472E-03 0,03989813 ! positive regulation of cell cycle GO:0045787 89 48 2,000 5,556E-03 0,04038708 ! mitochondrial transport GO:0006839 82 48 2,000 5,556E-03 0,04026544 ! cellular component disassembly GO:0022411 86 48 2,000 5,556E-03 0,04014452 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 5,556E-03 0,04002433 ! activation of caspase activity GO:0006919 84 48 2,000 5,556E-03 0,03990485 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 5,556E-03 0,03978609 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 5,682E-03 0,04056854 ! regulation of action potential GO:0001508 95 49 2,000 5,886E-03 0,04190084 ! response to temperature stimulus GO:0009266 76 49 2,000 5,886E-03 0,04177724 ! immunoglobulin mediated immune response GO:0016064 83 49 2,000 5,886E-03 0,04165437 GO:0019724|B cell mediated immunity, ! positive regulation of immune response GO:0050778 156 96 3,000 5,895E-03 0,04159543 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 6,114E-03 0,04300913 ! regulation of protein localization GO:0032880 176 97 3,000 6,114E-03 0,04288374 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,223E-03 0,04352788 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 6,223E-03 0,04340172 ! startle response GO:0001964 28 16 1,000 6,223E-03 0,04327628 ! complement activation, alternative pathway GO:0006957 18 16 1,000 6,223E-03 0,04315156 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 6,223E-03 0,04302756 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 1,000 6,223E-03 0,04290428 ! intermediate filament-based process GO:0045103 32 16 1,000 6,223E-03 0,04278169 ! axon cargo transport GO:0008088 43 16 1,000 6,223E-03 0,04265981 ! DNA replication initiation GO:0006270 27 16 1,000 6,223E-03 0,04253861 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 6,223E-03 0,04241811 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 6,223E-03 0,04229828 ! defense response to virus GO:0051607 37 16 1,000 6,223E-03 0,04217913 ! interphase GO:0051325 213 98 3,000 6,337E-03 0,04282858 ! skeletal muscle tissue development GO:0007519 186 99 3,000 6,566E-03 0,04425133 GO:0060538|skeletal muscle organ development, ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 6,581E-03 0,04423048 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 2,000 6,581E-03 0,04410727 ! regulation of angiogenesis GO:0045765 114 52 2,000 6,946E-03 0,04642403 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 6,946E-03 0,04629543 ! metencephalon development GO:0022037 30 17 1,000 7,019E-03 0,04664917 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 7,019E-03 0,04652066 ! inositol metabolic process GO:0006020 28 17 1,000 7,019E-03 0,04639286 ! glial cell development GO:0021782 27 17 1,000 7,019E-03 0,04626575 ! limbic system development GO:0021761 36 17 1,000 7,019E-03 0,04613934 ! regulation of viral genome replication GO:0045069 28 17 1,000 7,019E-03 0,04601362 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 7,019E-03 0,04588859 ! regulation of protein binding GO:0043393 33 17 1,000 7,019E-03 0,04576423 ! DNA unwinding during replication GO:0006268 27 17 1,000 7,019E-03 0,04564054 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 7,019E-03 0,04551752 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 7,019E-03 0,04539516 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 7,019E-03 0,04527346 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 7,323E-03 0,04711008 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,857E-03 0,05041315 ! positive regulation of proteolysis GO:0045862 31 18 1,000 7,857E-03 0,05027908 ! epidermis morphogenesis GO:0048730 40 18 1,000 7,857E-03 0,05014571 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 7,857E-03 0,05001305 ! aromatic compound catabolic process GO:0019439 27 18 1,000 7,857E-03 0,04988109 ! positive regulation of synaptic transmission GO:0050806 28 18 1,000 7,857E-03 0,04974982 ! positive regulation of caspase activity GO:0043280 95 55 2,000 8,112E-03 0,05122886 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 8,112E-03 0,05109475 ! aging GO:0007568 103 55 2,000 8,112E-03 0,05096134 ! skeletal muscle fiber development GO:0048741 111 56 2,000 8,525E-03 0,0534143 ! regulation of DNA replication GO:0006275 101 56 2,000 8,525E-03 0,05327556 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 8,739E-03 0,05447083 ! lipid phosphorylation GO:0046834 35 19 1,000 8,739E-03 0,05433007 ! cerebral cortex development GO:0021987 36 19 1,000 8,739E-03 0,05419005 ! actin filament bundle formation GO:0051017 42 19 1,000 8,739E-03 0,05405074 ! neuromuscular junction development GO:0007528 34 19 1,000 8,739E-03 0,05391215 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 8,739E-03 0,05377427 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 8,739E-03 0,05363709 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 1,000 8,739E-03 0,05350061 ! regulation of bone remodeling GO:0046850 137 57 2,000 8,95E-03 0,05465268 ! muscle fiber development GO:0048747 112 57 2,000 8,95E-03 0,05451432 ! regulation of intracellular transport GO:0032386 101 57 2,000 8,95E-03 0,05437666 ! regulation of tissue remodeling GO:0034103 140 58 2,000 9,387E-03 0,05688807 ! protein amino acid acetylation GO:0006473 39 20 1,000 9,662E-03 0,05841151 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 9,662E-03 0,05826511 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 9,662E-03 0,05811945 GO:0010675|regulation of cellular carbohydrate metabolic process, ! DNA duplex unwinding GO:0032508 31 20 1,000 9,662E-03 0,05797451 GO:0032392|DNA geometric change, ! diencephalon development GO:0021536 34 20 1,000 9,662E-03 0,0578303 ! positive regulation of neurological system process GO:0031646 32 20 1,000 9,662E-03 0,0576868 ! negative regulation of T cell activation GO:0050868 40 20 1,000 9,662E-03 0,05754401 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 9,662E-03 0,05740193 ! skeletal system morphogenesis GO:0048705 105 59 2,000 9,836E-03 0,05828937 ! establishment of organelle localization GO:0051656 109 59 2,000 9,836E-03 0,05814615 ! nucleoside metabolic process GO:0009116 81 60 2,000 0,01029762 0,06072564 ! kidney development GO:0001822 122 60 2,000 0,01029762 0,06057717 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 0,01062737 0,06236449 ! axis specification GO:0009798 38 21 1,000 0,01062737 0,06221275 ! ovarian follicle development GO:0001541 35 21 1,000 0,01062737 0,06206175 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 0,01062737 0,06191148 ! oogenesis GO:0048477 36 21 1,000 0,01062737 0,06176193 ! DNA modification GO:0006304 34 21 1,000 0,01062737 0,06161311 ! positive regulation of locomotion GO:0040017 39 21 1,000 0,01062737 0,061465 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 0,01062737 0,0613176 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 0,01062737 0,06117091 ! response to cytokine stimulus GO:0034097 63 21 1,000 0,01062737 0,06102492 ! gut development GO:0048565 39 21 1,000 0,01062737 0,06087962 ! ear development GO:0043583 103 62 2,000 0,01125802 0,06433918 ! microtubule-based transport GO:0010970 54 22 1,000 0,01163305 0,06632493 ! regulation of chemotaxis GO:0050920 40 22 1,000 0,01163305 0,06616814 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 0,01163305 0,06601208 ! positive regulation of B cell activation GO:0050871 38 22 1,000 0,01163305 0,06585676 ! activation of JUN kinase activity GO:0007257 42 22 1,000 0,01163305 0,06570216 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 0,01163305 0,0655483 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 0,01163305 0,06539515 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 0,01163305 0,06524271 ! regeneration GO:0031099 41 22 1,000 0,01163305 0,06509098 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 0,01163305 0,06493996 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 0,01163305 0,06478963 ! vacuolar transport GO:0007034 36 22 1,000 0,01163305 0,06464 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 0,01163305 0,06449106 ! apoptotic nuclear changes GO:0030262 32 22 1,000 0,01163305 0,06434281 ! ureteric bud development GO:0001657 43 22 1,000 0,01163305 0,06419523 ! lymphocyte mediated immunity GO:0002449 114 64 2,000 0,01226842 0,06754652 ! positive regulation of DNA replication GO:0045740 43 23 1,000 0,01267882 0,06964667 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 0,01267882 0,06948802 ! protein amino acid O-linked glycosylation GO:0006493 42 23 1,000 0,01267882 0,0693301 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 0,01267882 0,06917289 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 0,01267882 0,06901639 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! vesicle targeting GO:0006903 43 23 1,000 0,01267882 0,06886059 ! sex determination GO:0007530 47 23 1,000 0,01267882 0,0687055 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 0,01267882 0,06855111 ! regulation of viral reproduction GO:0050792 38 23 1,000 0,01267882 0,06839741 ! synaptic vesicle transport GO:0048489 46 23 1,000 0,01267882 0,06824439 ! germ cell development GO:0007281 118 65 2,000 0,0127925 0,06870259 ! developmental maturation GO:0021700 116 66 2,000 0,01332922 0,07142564 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01376402 0,07359165 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 0,01376402 0,07342847 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 0,01376402 0,07326602 ! multicellular organismal response to stress GO:0033555 49 24 1,000 0,01376402 0,07310428 ! digestive system process GO:0022600 39 24 1,000 0,01376402 0,07294326 ! regulation of behavior GO:0050795 43 24 1,000 0,01376402 0,07278295 ! lymphocyte proliferation GO:0046651 48 24 1,000 0,01376402 0,07262333 ! pallium development GO:0021543 49 24 1,000 0,01376402 0,07246442 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 0,01376402 0,0723062 ! regulation of cellular response to stress GO:0080135 128 67 2,000 0,01387863 0,07274941 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 0,01387863 0,07259126 ! activation of MAPK activity GO:0000187 115 67 2,000 0,01387863 0,0724338 ! homeostasis of number of cells GO:0048872 114 67 2,000 0,01387863 0,07227701 ! negative regulation of kinase activity GO:0033673 131 68 2,000 0,01444075 0,07504202 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 0,01444075 0,07488029 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01488802 0,07703348 ! vasculogenesis GO:0001570 46 25 1,000 0,01488802 0,07686818 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01488802 0,07670358 ! negative regulation of DNA replication GO:0008156 42 25 1,000 0,01488802 0,07653968 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01488802 0,07637648 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 0,01488802 0,07621398 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 0,01488802 0,07605217 ! somitogenesis GO:0001756 43 25 1,000 0,01488802 0,07589104 ! cell cycle checkpoint GO:0000075 137 69 2,000 0,01501564 0,07637974 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 0,01605017 0,08146984 ! macromolecular complex disassembly GO:0032984 53 26 1,000 0,01605017 0,08129832 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01605017 0,08112753 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 0,01605017 0,08095745 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01605017 0,08078808 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01605017 0,08061942 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01605017 0,08045147 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 52 26 1,000 0,01605017 0,08028421 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 0,01605017 0,08011764 ! reproductive structure development GO:0048608 113 71 2,000 0,01620378 0,08071699 ! B cell activation GO:0042113 160 71 2,000 0,01620378 0,08055022 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 0,01620378 0,08038414 ! acute inflammatory response GO:0002526 113 72 2,000 0,01681711 0,08325506 ! regulation of caspase activity GO:0043281 122 72 2,000 0,01681711 0,08308411 ! carbohydrate transport GO:0008643 110 72 2,000 0,01681711 0,08291385 ! negative regulation of transferase activity GO:0051348 140 72 2,000 0,01681711 0,08274429 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01724985 0,08470027 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01724985 0,08452777 ! male gonad development GO:0008584 44 27 1,000 0,01724985 0,08435596 ! response to toxin GO:0009636 47 27 1,000 0,01724985 0,08418485 ! base-excision repair GO:0006284 41 27 1,000 0,01724985 0,08401444 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01724985 0,08384471 ! axon guidance GO:0007411 139 73 2,000 0,01744329 0,08461403 ! leukocyte mediated immunity GO:0002443 128 74 2,000 0,01808236 0,08753753 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01808236 0,08736175 ! organelle localization GO:0051640 136 74 2,000 0,01808236 0,08718668 ! dendrite development GO:0016358 59 28 1,000 0,01848644 0,08895673 ! negative regulation of protein modification process GO:0031400 60 28 1,000 0,01848644 0,08877917 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01848644 0,08860232 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01848644 0,08842617 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01873432 0,08943409 ! lymphocyte differentiation GO:0030098 167 75 2,000 0,01873432 0,08925699 ! regulation of catabolic process GO:0009894 161 76 2,000 0,0193992 0,09224204 ! regulation of pH GO:0006885 43 29 1,000 0,01975932 0,09376908 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01975932 0,09358449 ! immune response-activating signal transduction GO:0002757 47 29 1,000 0,01975932 0,09340063 GO:0002764|immune response-regulating signal transduction, ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01975932 0,09321749 ! tissue homeostasis GO:0001894 48 29 1,000 0,01975932 0,09303507 GO:0048871|multicellular organismal homeostasis, ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,02076773 0,09759211 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 0,02076773 0,09740187 ! protein oligomerization GO:0051259 139 78 2,000 0,02076773 0,09721238 ! myofibril assembly GO:0030239 47 30 1,000 0,02106789 0,09842592 GO:0055002|striated muscle cell development, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,02106789 0,09823517 ! neurotransmitter secretion GO:0007269 48 30 1,000 0,02106789 0,09804516 ! regulation of B cell activation GO:0050864 50 30 1,000 0,02106789 0,09785588 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,0214714 0,09953794 ! regulation of synaptic transmission GO:0050804 134 79 2,000 0,0214714 0,09934652 ! response to metal ion GO:0010038 140 80 2,000 0,02218801 0,10246518 ! protein import into nucleus GO:0006606 158 80 2,000 0,02218801 0,10226889 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,02241155 0,10310172 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,02241155 0,10290496 ! ovulation cycle process GO:0022602 49 31 1,000 0,02241155 0,10270895 ! peptide transport GO:0015833 55 31 1,000 0,02241155 0,10251369 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,02241155 0,10231916 ! iron ion homeostasis GO:0055072 54 31 1,000 0,02241155 0,10212538 ! T cell activation GO:0042110 168 81 2,000 0,02291757 0,10423378 ! nuclear import GO:0051170 161 81 2,000 0,02291757 0,10403711 ! cholesterol metabolic process GO:0008203 136 82 2,000 0,02366006 0,10720548 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,02378971 0,10759032 ! cholesterol transport GO:0030301 56 32 1,000 0,02378971 0,10738846 ! metanephros development GO:0001656 74 32 1,000 0,02378971 0,10718736 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,02378971 0,10698701 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,02378971 0,10678741 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,02378971 0,10658855 ! muscle cell development GO:0055001 49 32 1,000 0,02378971 0,10639043 ! ovulation cycle GO:0042698 51 32 1,000 0,02378971 0,10619305 ! hindbrain development GO:0030902 61 32 1,000 0,02378971 0,10599639 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 0,02518386 0,11200067 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,02520179 0,11187361 ! post-embryonic development GO:0009791 69 33 1,000 0,02520179 0,11166758 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,02520179 0,11146231 ! sterol transport GO:0015918 57 33 1,000 0,02520179 0,11125779 ! adult locomotory behavior GO:0008344 59 33 1,000 0,02520179 0,11105402 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,02520179 0,110851 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,02520179 0,11064872 ! glial cell differentiation GO:0010001 63 34 1,000 0,02664719 0,11678168 ! placenta development GO:0001890 53 34 1,000 0,02664719 0,11656935 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,02664719 0,11635779 ! response to inorganic substance GO:0010035 153 86 2,000 0,02675934 0,11663582 ! tube morphogenesis GO:0035239 176 86 2,000 0,02675934 0,11642491 ! protein localization in nucleus GO:0034504 176 87 2,000 0,02756644 0,11971994 ! regulation of protein transport GO:0051223 154 87 2,000 0,02756644 0,11950423 GO:0070201|regulation of establishment of protein localization, ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,02812536 0,12170793 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,02812536 0,12148942 ! female gonad development GO:0008585 58 35 1,000 0,02812536 0,1212717 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,02812536 0,12105475 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 1,000 0,02812536 0,12083858 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02812536 0,12062318 ! vesicle localization GO:0051648 64 35 1,000 0,02812536 0,12040855 ! regulation of DNA binding GO:0051101 155 88 2,000 0,02838642 0,12131033 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02963572 0,12642471 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02963572 0,12620095 ! positive regulation of cell development GO:0010720 80 36 1,000 0,02963572 0,12597798 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,02963572 0,12575579 ! regulation of proteolysis GO:0030162 72 36 1,000 0,02963572 0,12553439 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,02963572 0,12531377 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02963572 0,12509392 ! sterol metabolic process GO:0016125 152 91 2,000 0,03092347 0,13030101 ! response to protein stimulus GO:0051789 149 91 2,000 0,03092347 0,13007321 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,03117771 0,13091375 ! sister chromatid segregation GO:0000819 58 37 1,000 0,03117771 0,13068568 ! actomyosin structure organization GO:0031032 62 37 1,000 0,03117771 0,1304584 ! tissue remodeling GO:0048771 76 37 1,000 0,03117771 0,13023191 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,03117771 0,13000621 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,03117771 0,12978128 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,03117771 0,12955714 ! regulation of protein stability GO:0031647 73 37 1,000 0,03117771 0,12933376 ! pigment metabolic process GO:0042440 80 37 1,000 0,03117771 0,12911116 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,03267889 0,13509522 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,0327508 0,13516023 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,0327508 0,13492879 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,0327508 0,13469815 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,0327508 0,13446829 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,0327508 0,13423921 ! lipid homeostasis GO:0055088 67 38 1,000 0,0327508 0,13401091 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,0327508 0,13378339 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,0327508 0,13355664 ! mammary gland development GO:0030879 86 39 1,000 0,03435442 0,13985909 ! ear morphogenesis GO:0042471 60 39 1,000 0,03435442 0,13962285 ! organic ether metabolic process GO:0018904 55 39 1,000 0,03435442 0,13938739 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,03435442 0,13915273 ! segmentation GO:0035282 67 39 1,000 0,03435442 0,13891886 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,03435442 0,13868578 ! leukocyte differentiation GO:0002521 202 96 2,000 0,03540757 0,14269784 ! feeding behavior GO:0007631 59 40 1,000 0,03598803 0,14479466 ! negative regulation of binding GO:0051100 72 40 1,000 0,03598803 0,14455294 ! mesenchymal cell development GO:0014031 87 40 1,000 0,03598803 0,14431202 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 0,03598803 0,1440719 ! cytokinesis GO:0000910 72 40 1,000 0,03598803 0,14383257 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03680274 0,14684477 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03680274 0,14660165 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03680274 0,14635933 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03680274 0,14611782 ! neuron fate determination GO:0048664 7 5 0,000 0,03680274 0,1458771 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03680274 0,14563717 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03680274 0,14539802 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,03680274 0,14515967 ! polyol transport GO:0015791 12 5 0,000 0,03680274 0,14492209 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03680274 0,14468529 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03680274 0,14444926 ! response to superoxide GO:0000303 10 5 0,000 0,03680274 0,144214 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03680274 0,14397951 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03680274 0,14374577 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03680274 0,1435128 ! female meiosis GO:0007143 7 5 0,000 0,03680274 0,14328058 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03680274 0,14304911 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03680274 0,14281838 ! cobalt ion transport GO:0006824 11 5 0,000 0,03680274 0,1425884 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03680274 0,14235916 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03680274 0,14213065 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03680274 0,14190288 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03680274 0,14167584 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03680274 0,14144952 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03680274 0,14122392 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03680274 0,14099904 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03680274 0,14077488 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03680274 0,14055142 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03680274 0,14032868 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03680274 0,14010664 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03680274 0,1398853 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03680274 0,13966466 ! negative chemotaxis GO:0050919 14 5 0,000 0,03680274 0,13944472 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03680274 0,13922547 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03680274 0,1390069 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03680274 0,13878902 ! behavioral response to pain GO:0048266 9 5 0,000 0,03680274 0,13857183 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03680274 0,13835531 ! Notch receptor processing GO:0007220 8 5 0,000 0,03680274 0,13813946 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03680274 0,13792429 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03680274 0,13770979 ! micturition GO:0060073 9 5 0,000 0,03680274 0,13749596 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03680274 0,13728279 ! copulation GO:0007620 9 5 0,000 0,03680274 0,13707027 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03680274 0,13685842 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03680274 0,13664722 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03680274 0,13643667 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03680274 0,13622676 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03680274 0,13601751 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03680274 0,13580889 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03680274 0,13560091 ! grooming behavior GO:0007625 6 5 0,000 0,03680274 0,13539357 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03680274 0,13518687 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03680274 0,13498079 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03680274 0,13477534 ! response to protozoan GO:0001562 10 5 0,000 0,03680274 0,13457051 ! lymph vessel development GO:0001945 10 5 0,000 0,03680274 0,13436631 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03680274 0,13416272 ! endochondral ossification GO:0001958 16 5 0,000 0,03680274 0,13395975 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03680274 0,1337574 ! parathyroid gland development GO:0060017 13 5 0,000 0,03680274 0,13355565 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03680274 0,13335451 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03680274 0,13315398 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03680274 0,13295405 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03680274 0,13275472 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03680274 0,13255598 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03680274 0,13235784 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03680274 0,13216029 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03680274 0,13196333 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03680274 0,13176696 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03680274 0,13157117 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03680274 0,13137596 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03680274 0,13118133 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03680274 0,13098727 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03680274 0,13079379 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03680274 0,13060088 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03680274 0,13040854 ! histidine catabolic process GO:0006548 6 5 0,000 0,03680274 0,13021676 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03680274 0,13002555 ! valine metabolic process GO:0006573 10 5 0,000 0,03680274 0,12983489 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03680274 0,1296448 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03680274 0,12945526 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03680274 0,12926627 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03680274 0,12907784 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03680274 0,12888995 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03680274 0,12870261 ! polyol catabolic process GO:0046174 7 5 0,000 0,03680274 0,12851582 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03680274 0,12832956 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03680274 0,12814385 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03680274 0,12795867 ! muscle cell migration GO:0014812 8 5 0,000 0,03680274 0,12777402 ! mitochondrial fission GO:0000266 8 5 0,000 0,03680274 0,12758991 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03680274 0,12740633 ! mRNA transcription GO:0009299 9 5 0,000 0,03680274 0,12722327 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03680274 0,12704074 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03680274 0,12685873 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03680274 0,12667725 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03680274 0,12649628 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03680274 0,12631583 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03680274 0,12613589 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03680274 0,12595647 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03680274 0,12577755 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03680274 0,12559914 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03680274 0,12542124 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03680274 0,12524384 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03680274 0,12506694 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,03680274 0,12489055 ! forebrain neuron development GO:0021884 13 5 0,000 0,03680274 0,12471464 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03680274 0,12453924 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03680274 0,12436432 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03680274 0,1241899 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03680274 0,12401596 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03680274 0,12384251 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03680274 0,12366955 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03680274 0,12349707 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03680274 0,12332507 ! basic amino acid transport GO:0015802 11 5 0,000 0,03680274 0,12315354 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03680274 0,1229825 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03680274 0,12281192 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03680274 0,12264182 ! depyrimidination GO:0045008 10 5 0,000 0,03680274 0,1224722 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03680274 0,12230303 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03680274 0,12213434 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03680274 0,12196611 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03680274 0,12179835 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03680274 0,12163104 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03680274 0,12146419 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03680274 0,1212978 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03680274 0,12113187 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03680274 0,12096639 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03680274 0,12080136 ! response to arsenic GO:0046685 10 5 0,000 0,03680274 0,12063678 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03680274 0,12047265 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03680274 0,12030896 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03680274 0,12014572 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03680274 0,11998292 ! response to cadmium ion GO:0046686 7 5 0,000 0,03680274 0,11982056 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03680274 0,11965864 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03680274 0,11949716 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03680274 0,11933611 ! decidualization GO:0046697 11 5 0,000 0,03680274 0,1191755 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03680274 0,11901532 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03680274 0,11885557 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03680274 0,11869624 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03680274 0,11853735 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03680274 0,11837887 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03680274 0,11822082 ! neural tube patterning GO:0021532 7 5 0,000 0,03680274 0,1180632 ! embryonic cleavage GO:0040016 6 5 0,000 0,03680274 0,11790599 ! peroxisome fission GO:0016559 5 5 0,000 0,03680274 0,1177492 ! histone demethylation GO:0016577 10 5 0,000 0,03680274 0,11759282 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03680274 0,11743687 ! mitotic recombination GO:0006312 9 5 0,000 0,03680274 0,11728132 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03680274 0,11712619 ! metaphase plate congression GO:0051310 7 5 0,000 0,03680274 0,11697146 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03680274 0,11681715 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03680274 0,11666324 ! enteric nervous system development GO:0048484 8 5 0,000 0,03680274 0,11650973 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03680274 0,11635663 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03680274 0,11620393 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03680274 0,11605163 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03680274 0,11589973 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03680274 0,11574823 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03680274 0,11559712 ! plasminogen activation GO:0031639 5 5 0,000 0,03680274 0,11544641 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03680274 0,11529609 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03680274 0,11514616 ! metaphase GO:0051323 8 5 0,000 0,03680274 0,11499662 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03680274 0,11484747 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03680274 0,1146987 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03680274 0,11455032 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03680274 0,11440232 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03680274 0,11425471 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03680274 0,11410747 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03680274 0,11396061 ! response to redox state GO:0051775 5 5 0,000 0,03680274 0,11381413 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03680274 0,11366803 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03680274 0,1135223 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03680274 0,11337695 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03680274 0,11323197 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03680274 0,11308735 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03680274 0,11294311 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03680274 0,11279923 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03680274 0,11265572 ! striatum development GO:0021756 9 5 0,000 0,03680274 0,11251258 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03680274 0,11236979 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03680274 0,11222737 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03680274 0,11208531 ! glial cell migration GO:0008347 11 5 0,000 0,03680274 0,11194361 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03680274 0,11180227 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03680274 0,11166128 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03680274 0,11152065 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03680274 0,11138037 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03680274 0,11124045 ! neuroprotection GO:0043526 6 5 0,000 0,03680274 0,11110087 ! neural plate development GO:0001840 8 5 0,000 0,03680274 0,11096165 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03680274 0,11082277 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03680274 0,11068425 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03680274 0,11054606 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03680274 0,11040823 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03680274 0,11027073 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03680274 0,11013358 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03680274 0,10999677 ! spindle assembly GO:0051225 6 5 0,000 0,03680274 0,10986029 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03680274 0,10972416 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03680274 0,10958836 ! drug metabolic process GO:0017144 6 5 0,000 0,03680274 0,1094529 ! stem cell division GO:0017145 11 5 0,000 0,03680274 0,10931777 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,03680274 0,10918298 ! organ regeneration GO:0031100 7 5 0,000 0,03680274 0,10904852 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03680274 0,10891439 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03680274 0,10878059 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03680274 0,10864711 ! gliogenesis GO:0042063 88 41 1,000 0,03765112 0,11101542 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,03765112 0,11087954 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,03765112 0,11074399 ! female gamete generation GO:0007292 61 41 1,000 0,03765112 0,11060877 ! polyol metabolic process GO:0019751 66 41 1,000 0,03765112 0,11047389 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,03765112 0,11033933 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03934314 0,11515765 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,03934314 0,11501773 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,03934314 0,11487814 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,03934314 0,11473889 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,04106357 0,11961133 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,04106357 0,1194667 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,04106357 0,11932242 ! male sex differentiation GO:0046661 76 44 1,000 0,04281191 0,12425267 ! double-strand break repair GO:0006302 81 44 1,000 0,04281191 0,12410297 ! biopolymer methylation GO:0043414 84 44 1,000 0,04281191 0,12395363 ! maintenance of location in cell GO:0051651 97 44 1,000 0,04281191 0,12380465 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04399985 0,12708721 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04399985 0,12693483 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,04399985 0,12678281 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04399985 0,12663115 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04399985 0,12647986 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,04399985 0,12632893 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,04399985 0,12617836 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,04399985 0,12602815 ! sleep GO:0030431 13 6 0,000 0,04399985 0,12587829 ! response to oxygen radical GO:0000305 11 6 0,000 0,04399985 0,12572879 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,04399985 0,12557965 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,04399985 0,12543086 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,04399985 0,12528242 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,04399985 0,12513433 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04399985 0,12498659 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,04399985 0,1248392 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,04399985 0,12469216 ! forebrain regionalization GO:0021871 8 6 0,000 0,04399985 0,12454546 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04399985 0,12439911 ! male meiosis GO:0007140 7 6 0,000 0,04399985 0,1242531 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04399985 0,12410744 ! response to zinc ion GO:0010043 9 6 0,000 0,04399985 0,12396211 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04399985 0,12381713 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,04399985 0,12367248 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04399985 0,12352817 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04399985 0,1233842 ! malate metabolic process GO:0006108 11 6 0,000 0,04399985 0,12324056 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,04399985 0,12309726 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,04399985 0,12295429 ! protein refolding GO:0042026 15 6 0,000 0,04399985 0,12281165 ! opsonization GO:0008228 8 6 0,000 0,04399985 0,12266934 ! mating behavior GO:0007617 7 6 0,000 0,04399985 0,12252737 ! neuron remodeling GO:0016322 15 6 0,000 0,04399985 0,12238572 ! erythrocyte maturation GO:0043249 7 6 0,000 0,04399985 0,12224439 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,04399985 0,1221034 ! equilibrioception GO:0050957 14 6 0,000 0,04399985 0,12196272 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,04399985 0,12182238 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,04399985 0,12168235 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04399985 0,12154265 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,04399985 0,12140326 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04399985 0,1212642 ! response to interferon-gamma GO:0034341 15 6 0,000 0,04399985 0,12112545 ! toxin metabolic process GO:0009404 11 6 0,000 0,04399985 0,12098702 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04399985 0,12084891 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04399985 0,12071111 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,04399985 0,12057363 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,04399985 0,12043646 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,04399985 0,1202996 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,04399985 0,12016305 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,04399985 0,12002681 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,04399985 0,11989088 ! thymic T cell selection GO:0045061 12 6 0,000 0,04399985 0,11975525 ! protein lipoylation GO:0009249 10 6 0,000 0,04399985 0,11961994 ! cysteine metabolic process GO:0006534 10 6 0,000 0,04399985 0,11948493 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,04399985 0,11935022 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04399985 0,11921582 ! glutamate catabolic process GO:0006538 10 6 0,000 0,04399985 0,11908171 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,04399985 0,11894791 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,04399985 0,11881442 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,04399985 0,11868122 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,04399985 0,11854831 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,04399985 0,11841571 ! hyperosmotic response GO:0006972 9 6 0,000 0,04399985 0,1182834 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,04399985 0,11815139 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,04399985 0,11801967 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04399985 0,11788825 ! urea metabolic process GO:0019627 7 6 0,000 0,04399985 0,11775711 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04399985 0,11762627 ! neutrophil activation GO:0042119 8 6 0,000 0,04399985 0,11749572 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04399985 0,11736546 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,04399985 0,11723549 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04399985 0,1171058 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04399985 0,1169764 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04399985 0,11684729 ! neuron apoptosis GO:0051402 9 6 0,000 0,04399985 0,11671846 ! nucleoside salvage GO:0043174 9 6 0,000 0,04399985 0,11658992 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,04399985 0,11646165 ! T cell mediated immunity GO:0002456 16 6 0,000 0,04399985 0,11633367 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,04399985 0,11620598 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,04399985 0,11607856 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,04399985 0,11595142 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04399985 0,11582456 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,04399985 0,11569797 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,04399985 0,11557166 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,04399985 0,11544563 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,04399985 0,11531987 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,04399985 0,11519439 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,04399985 0,11506918 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,04399985 0,11494424 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,04399985 0,11481957 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,04399985 0,11469517 ! response to UV-C GO:0010225 11 6 0,000 0,04399985 0,11457104 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,04399985 0,11444718 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,04399985 0,11432359 ! interaction with symbiont GO:0051702 13 6 0,000 0,04399985 0,11420026 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04399985 0,1140772 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04399985 0,11395441 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,04399985 0,11383188 ! response to copper ion GO:0046688 10 6 0,000 0,04399985 0,11370961 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,04399985 0,1135876 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,04399985 0,11346586 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04399985 0,11334437 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04399985 0,11322315 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,04399985 0,11310218 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,04399985 0,11298148 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04399985 0,11286103 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,04399985 0,11274084 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04399985 0,1126209 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,04399985 0,11250122 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04399985 0,11238179 ! subpallium development GO:0021544 10 6 0,000 0,04399985 0,11226261 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,04399985 0,11214369 ! histone ubiquitination GO:0016574 8 6 0,000 0,04399985 0,11202502 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,04399985 0,1119066 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04399985 0,11178843 ! G2 phase GO:0051319 16 6 0,000 0,04399985 0,11167051 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,04399985 0,11155284 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04399985 0,11143541 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,04399985 0,11131824 ! membrane to membrane docking GO:0022614 14 6 0,000 0,04399985 0,11120131 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04399985 0,11108462 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,04399985 0,11096818 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04399985 0,11085198 ! receptor internalization GO:0031623 10 6 0,000 0,04399985 0,11073603 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,04399985 0,11062032 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,04399985 0,11050485 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04399985 0,11038962 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,04399985 0,11027463 ! protein deubiquitination GO:0016579 14 6 0,000 0,04399985 0,11015988 ! protein destabilization GO:0031648 9 6 0,000 0,04399985 0,11004537 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04399985 0,10993109 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,04399985 0,10981706 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04399985 0,10970326 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,04399985 0,10958969 ! progesterone metabolic process GO:0042448 10 6 0,000 0,04399985 0,10947636 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,04399985 0,10936327 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,04399985 0,10925041 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,04399985 0,10913778 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,04399985 0,10902538 ! determination of adult lifespan GO:0008340 15 6 0,000 0,04399985 0,10891321 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,04399985 0,10880128 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,04399985 0,10868957 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04399985 0,1085781 ! catecholamine transport GO:0051937 9 6 0,000 0,04399985 0,10846685 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,04399985 0,10835583 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04399985 0,10824503 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04399985 0,10813447 ! maternal placenta development GO:0001893 12 6 0,000 0,04399985 0,10802413 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,04399985 0,10791401 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04399985 0,10780412 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,04399985 0,10769445 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,04399985 0,107585 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04399985 0,10747578 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,04399985 0,10736678 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,04399985 0,107258 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,04458765 0,10858085 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,04458765 0,10847106 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,04639027 0,11274241 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,04639027 0,11262865 ! endosome transport GO:0016197 108 47 1,000 0,04821929 0,11695121 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,04821929 0,11683343 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,04821929 0,1167159 ! JNK cascade GO:0007254 91 47 1,000 0,04821929 0,11659859 ! methylation GO:0032259 90 47 1,000 0,04821929 0,11648153 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,0500742 0,12084106 ! tRNA transcription GO:0009304 14 7 0,000 0,05114342 0,12329767 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,05114342 0,12317425 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,05114342 0,12305107 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,05114342 0,12292815 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,05114342 0,12280546 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,05114342 0,12268302 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,05114342 0,12256083 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,05114342 0,12243888 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,05114342 0,12231717 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,05114342 0,1221957 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05114342 0,12207448 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,05114342 0,12195349 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,05114342 0,12183275 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05114342 0,12171224 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,05114342 0,12159197 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,05114342 0,12147194 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,05114342 0,12135214 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,05114342 0,12123258 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,05114342 0,12111326 ! glycolipid transport GO:0046836 10 7 0,000 0,05114342 0,12099417 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,05114342 0,12087532 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,05114342 0,1207567 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,05114342 0,12063831 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,05114342 0,12052015 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,05114342 0,12040222 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,05114342 0,12028453 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,05114342 0,12016706 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,05114342 0,12004983 ! pericardium development GO:0060039 14 7 0,000 0,05114342 0,11993282 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,05114342 0,11981604 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,05114342 0,11969949 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,05114342 0,11958316 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05114342 0,11946706 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,05114342 0,11935119 ! lipoprotein transport GO:0042953 14 7 0,000 0,05114342 0,11923554 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05114342 0,11912011 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05114342 0,11900491 ! rhythmic behavior GO:0007622 15 7 0,000 0,05114342 0,11888993 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,05114342 0,11877517 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,05114342 0,11866063 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,05114342 0,11854631 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,05114342 0,11843222 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,05114342 0,11831834 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,05114342 0,11820468 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,05114342 0,11809124 ! mechanosensory behavior GO:0007638 14 7 0,000 0,05114342 0,11797802 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,05114342 0,11786501 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05114342 0,11775222 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,05114342 0,11763965 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05114342 0,11752729 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05114342 0,11741515 ! spinal cord patterning GO:0021511 13 7 0,000 0,05114342 0,11730322 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,05114342 0,1171915 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,05114342 0,11707999 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,05114342 0,1169687 ! adrenal gland development GO:0030325 17 7 0,000 0,05114342 0,11685762 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,05114342 0,11674675 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,05114342 0,11663609 ! ovulation GO:0030728 9 7 0,000 0,05114342 0,11652564 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,05114342 0,1164154 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,05114342 0,11630536 ! microtubule nucleation GO:0007020 20 7 0,000 0,05114342 0,11619554 ! proline biosynthetic process GO:0006561 10 7 0,000 0,05114342 0,11608592 ! thyroid hormone generation GO:0006590 13 7 0,000 0,05114342 0,11597651 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,05114342 0,1158673 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,05114342 0,1157583 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,05114342 0,11564951 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05114342 0,11554091 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05114342 0,11543253 ! galactose metabolic process GO:0006012 13 7 0,000 0,05114342 0,11532434 ! vesicle fusion GO:0006906 17 7 0,000 0,05114342 0,11521636 ! response to dietary excess GO:0002021 8 7 0,000 0,05114342 0,11510858 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,05114342 0,115001 ! intracellular pH reduction GO:0051452 11 7 0,000 0,05114342 0,11489363 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,05114342 0,11478645 ! purine salvage GO:0043101 10 7 0,000 0,05114342 0,11467947 ! nucleoside transport GO:0015858 8 7 0,000 0,05114342 0,11457269 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,05114342 0,11446611 ! parturition GO:0007567 14 7 0,000 0,05114342 0,11435973 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,05114342 0,11425355 ! rRNA modification GO:0000154 14 7 0,000 0,05114342 0,11414756 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,05114342 0,11404177 ! spindle checkpoint GO:0031577 15 7 0,000 0,05114342 0,11393618 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,05114342 0,11383078 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,05114342 0,11372558 ! macrophage differentiation GO:0030225 11 7 0,000 0,05114342 0,11362057 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05114342 0,11351575 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,05114342 0,11341113 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,05114342 0,1133067 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,05114342 0,11320246 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,05114342 0,11309841 ! fibrinolysis GO:0042730 10 7 0,000 0,05114342 0,11299456 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,05114342 0,11289089 ! eating behavior GO:0042755 7 7 0,000 0,05114342 0,11278742 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,05114342 0,11268413 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,05114342 0,11258104 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,05114342 0,11247813 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,05114342 0,11237541 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,05114342 0,11227288 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,05114342 0,11217053 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,05114342 0,11206837 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,05114342 0,1119664 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,05114342 0,11186461 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,05114342 0,11176301 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,05114342 0,11166159 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,05114342 0,11156036 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,05114342 0,11145931 ! regulation of meiosis GO:0040020 12 7 0,000 0,05114342 0,11135844 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,05114342 0,11125775 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,05114342 0,11115725 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,05114342 0,11105693 ! oxygen homeostasis GO:0032364 12 7 0,000 0,05114342 0,11095678 ! transcription termination GO:0006353 13 7 0,000 0,05114342 0,11085682 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,05114342 0,11075704 ! anaphase GO:0051322 17 7 0,000 0,05114342 0,11065744 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,05114342 0,11055802 ! axonal fasciculation GO:0007413 18 7 0,000 0,05114342 0,11045877 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,05114342 0,11035971 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,05114342 0,11026082 ! diuresis GO:0030146 12 7 0,000 0,05114342 0,11016211 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,05114342 0,11006357 ! thiamin metabolic process GO:0006772 7 7 0,000 0,05114342 0,10996521 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05114342 0,10986703 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,05114342 0,10976902 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,05114342 0,10967119 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,05114342 0,10957353 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05114342 0,10947604 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05114342 0,10937873 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05114342 0,10928159 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,05114342 0,10918463 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,05114342 0,10908783 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,05114342 0,10899121 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,05114342 0,10889476 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,05114342 0,10879847 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05114342 0,10870236 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,05114342 0,10860642 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,05114342 0,10851065 ! adult feeding behavior GO:0008343 9 7 0,000 0,05114342 0,10841504 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,05114342 0,10831961 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,05114342 0,10822434 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,05114342 0,10812924 ! muscle adaptation GO:0043500 14 7 0,000 0,05114342 0,1080343 ! embryonic heart tube development GO:0035050 10 7 0,000 0,05114342 0,10793954 ! retina homeostasis GO:0001895 12 7 0,000 0,05114342 0,10784494 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,05114342 0,1077505 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,05114342 0,10765623 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,05114342 0,10756213 ! protein prenylation GO:0018342 18 7 0,000 0,05114342 0,10746819 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,05114342 0,10737441 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,05114342 0,1072808 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05114342 0,10718735 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,05195454 0,10879253 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,05195454 0,10869793 ! endocrine system development GO:0035270 104 49 1,000 0,05195454 0,10860349 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,05195454 0,10850922 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,05385981 0,1123909 ! neuromuscular process GO:0050905 99 50 1,000 0,05385981 0,11229351 ! regulation of ossification GO:0030278 117 50 1,000 0,05385981 0,11219628 ! histone modification GO:0016570 91 50 1,000 0,05385981 0,11209923 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,05385981 0,11200234 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,05385981 0,11190562 ! positive regulation of binding GO:0051099 78 51 1,000 0,05578955 0,11581506 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,05578955 0,11571522 ! vesicle organization GO:0016050 107 51 1,000 0,05578955 0,11561555 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,05578955 0,11551605 ! covalent chromatin modification GO:0016569 101 52 1,000 0,05774328 0,11945859 ! cartilage development GO:0051216 90 52 1,000 0,05774328 0,11935596 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05823385 0,12026664 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05823385 0,1201635 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,05823385 0,12006053 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05823385 0,11995774 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05823385 0,11985512 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05823385 0,11975268 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05823385 0,11965042 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05823385 0,11954833 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05823385 0,11944641 ! meiotic prophase I GO:0007128 13 8 0,000 0,05823385 0,11934467 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05823385 0,1192431 ! UTP metabolic process GO:0046051 8 8 0,000 0,05823385 0,1191417 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,05823385 0,11904047 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05823385 0,11893942 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05823385 0,11883854 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05823385 0,11873783 ! succinate metabolic process GO:0006105 14 8 0,000 0,05823385 0,11863729 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05823385 0,11853692 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,05823385 0,11843672 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05823385 0,11833669 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05823385 0,11823683 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05823385 0,11813713 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05823385 0,11803761 ! reflex GO:0060004 16 8 0,000 0,05823385 0,11793825 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05823385 0,11783906 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05823385 0,11774003 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05823385 0,11764117 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05823385 0,11754248 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,05823385 0,11744396 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05823385 0,11734559 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05823385 0,1172474 ! histidine metabolic process GO:0006547 16 8 0,000 0,05823385 0,11714936 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05823385 0,11705149 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05823385 0,11695379 ! glycine catabolic process GO:0006546 13 8 0,000 0,05823385 0,11685625 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05823385 0,11675887 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05823385 0,11666165 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,05823385 0,11656459 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05823385 0,1164677 ! macrophage activation GO:0042116 12 8 0,000 0,05823385 0,11637096 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05823385 0,11627439 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,05823385 0,11617798 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05823385 0,11608172 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,05823385 0,11598563 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05823385 0,11588969 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,05823385 0,11579392 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05823385 0,1156983 ! osteoblast development GO:0002076 16 8 0,000 0,05823385 0,11560284 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05823385 0,11550753 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05823385 0,11541239 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05823385 0,1153174 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05823385 0,11522256 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05823385 0,11512789 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05823385 0,11503337 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05823385 0,114939 ! intermediate filament organization GO:0045109 12 8 0,000 0,05823385 0,11484479 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05823385 0,11475073 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,05823385 0,11465682 ! cellular extravasation GO:0045123 12 8 0,000 0,05823385 0,11456307 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05823385 0,11446948 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05823385 0,11437603 ! response to antibiotic GO:0046677 11 8 0,000 0,05823385 0,11428274 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05823385 0,1141896 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05823385 0,11409661 ! DNA topological change GO:0006265 12 8 0,000 0,05823385 0,11400377 ! response to tropane GO:0014073 15 8 0,000 0,05823385 0,11391109 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05823385 0,11381855 ! melanosome transport GO:0032402 13 8 0,000 0,05823385 0,11372617 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05823385 0,11363393 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05823385 0,11354185 ! mast cell activation GO:0045576 14 8 0,000 0,05823385 0,11344991 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05823385 0,11335812 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05823385 0,11326648 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05823385 0,11317499 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05823385 0,11308365 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05823385 0,11299245 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05823385 0,1129014 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,05823385 0,1128105 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05823385 0,11271974 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05823385 0,11262913 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05823385 0,11253867 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05823385 0,11244835 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05823385 0,11235817 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05823385 0,11226814 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05823385 0,11217825 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05823385 0,11208851 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05823385 0,11199891 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05823385 0,11190946 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05823385 0,11182014 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05823385 0,11173097 ! hormone catabolic process GO:0042447 17 8 0,000 0,05823385 0,11164194 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05823385 0,11155306 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05823385 0,11146431 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05823385 0,11137571 ! ATP catabolic process GO:0006200 11 8 0,000 0,05823385 0,11128724 ! blastocyst growth GO:0001832 19 8 0,000 0,05823385 0,11119892 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05823385 0,11111074 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05823385 0,11102269 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05823385 0,11093479 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05823385 0,11084702 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05823385 0,1107594 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05823385 0,11067191 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05823385 0,11058456 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05823385 0,11049735 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05823385 0,11041027 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05823385 0,11032334 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05823385 0,11023654 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05823385 0,11014987 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05823385 0,11006335 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05823385 0,10997695 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05823385 0,1098907 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05823385 0,10980458 ! cell maturation GO:0048469 100 53 1,000 0,05972055 0,11251968 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,06172089 0,11619754 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,06172089 0,11610669 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,06374385 0,11981853 ! heart morphogenesis GO:0003007 97 55 1,000 0,06374385 0,11972499 ! nuclear export GO:0051168 97 55 1,000 0,06374385 0,1196316 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,06374385 0,11953836 ! axon extension GO:0048675 15 9 0,000 0,06527152 0,12230786 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,06527152 0,12221267 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,06527152 0,12211764 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,06527152 0,12202276 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,06527152 0,12192802 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,06527152 0,12183343 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,06527152 0,12173898 ! phosphate transport GO:0006817 19 9 0,000 0,06527152 0,12164468 ! reproductive behavior GO:0019098 19 9 0,000 0,06527152 0,12155053 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,06527152 0,12145653 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,06527152 0,12136266 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06527152 0,12126895 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,06527152 0,12117538 ! GTP metabolic process GO:0046039 9 9 0,000 0,06527152 0,12108195 ! RNA methylation GO:0001510 15 9 0,000 0,06527152 0,12098866 ! elastic fiber assembly GO:0048251 15 9 0,000 0,06527152 0,12089552 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,06527152 0,12080253 ! artery development GO:0060840 24 9 0,000 0,06527152 0,12070967 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,06527152 0,12061696 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,06527152 0,1205244 ! chemosensory behavior GO:0007635 20 9 0,000 0,06527152 0,12043197 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,06527152 0,12033968 ! leukocyte degranulation GO:0043299 16 9 0,000 0,06527152 0,12024754 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,06527152 0,12015554 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,06527152 0,12006367 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,06527152 0,11997195 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,06527152 0,11988037 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,06527152 0,11978893 ! protein targeting to ER GO:0045047 22 9 0,000 0,06527152 0,11969763 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,06527152 0,11960646 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,06527152 0,11951544 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,06527152 0,11942455 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06527152 0,1193338 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,06527152 0,11924319 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,06527152 0,11915272 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06527152 0,11906239 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,06527152 0,11897219 ! mannose metabolic process GO:0006013 13 9 0,000 0,06527152 0,11888212 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,06527152 0,1187922 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,06527152 0,11870241 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,06527152 0,11861275 ! receptor clustering GO:0043113 18 9 0,000 0,06527152 0,11852324 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,06527152 0,11843385 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,06527152 0,1183446 ! ruffle organization GO:0031529 15 9 0,000 0,06527152 0,11825549 ! retinol metabolic process GO:0042572 18 9 0,000 0,06527152 0,11816651 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,06527152 0,11807766 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,06527152 0,11798895 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,06527152 0,11790037 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,06527152 0,11781192 ! segment specification GO:0007379 13 9 0,000 0,06527152 0,1177236 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,06527152 0,11763542 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,06527152 0,11754737 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,06527152 0,11745945 ! response to amine stimulus GO:0014075 13 9 0,000 0,06527152 0,11737166 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,06527152 0,11728401 ! erythrocyte development GO:0048821 15 9 0,000 0,06527152 0,11719648 ! gas homeostasis GO:0033483 16 9 0,000 0,06527152 0,11710909 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,06527152 0,11702182 ! renal water homeostasis GO:0003091 14 9 0,000 0,06527152 0,11693469 ! postreplication repair GO:0006301 22 9 0,000 0,06527152 0,11684768 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,06527152 0,11676081 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,06527152 0,11667406 ! icosanoid secretion GO:0032309 15 9 0,000 0,06527152 0,11658744 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,06527152 0,11650095 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,06527152 0,11641459 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,06527152 0,11632836 ! regulation of cell division GO:0051302 15 9 0,000 0,06527152 0,11624226 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,06527152 0,11615628 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,06527152 0,11607043 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,06527152 0,1159847 ! sterol catabolic process GO:0016127 11 9 0,000 0,06527152 0,1158991 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,06527152 0,11581363 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,06527152 0,11572829 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,06527152 0,11564307 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,06527152 0,11555797 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,06527152 0,11547301 ! musculoskeletal movement GO:0050881 14 9 0,000 0,06527152 0,11538816 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,06527152 0,11530344 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,06527152 0,11521885 ! purine base metabolic process GO:0006144 21 9 0,000 0,06527152 0,11513437 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,06527152 0,11505003 ! pigment granule transport GO:0051904 17 9 0,000 0,06527152 0,1149658 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,06527152 0,1148817 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,06527152 0,11479772 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,06527152 0,11471387 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06527152 0,11463014 ! mitochondrion localization GO:0051646 15 9 0,000 0,06527152 0,11454653 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,065789 0,1153705 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,065789 0,11528647 ! lipid modification GO:0030258 97 57 1,000 0,06785588 0,11882187 ! maintenance of location GO:0051235 118 57 1,000 0,06785588 0,11873545 ! adult behavior GO:0030534 99 58 1,000 0,06994406 0,12230044 ! DNA catabolic process GO:0006308 86 59 1,000 0,07205311 0,12589673 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,07225684 0,12616107 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,07225684 0,12606959 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,07225684 0,12597823 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,07225684 0,12588701 ! synapsis GO:0007129 13 10 0,000 0,07225684 0,12579592 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,07225684 0,12570496 ! N-glycan processing GO:0006491 20 10 0,000 0,07225684 0,12561413 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,07225684 0,12552344 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,07225684 0,12543287 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,07225684 0,12534244 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,07225684 0,12525213 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,07225684 0,12516196 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,07225684 0,12507191 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,07225684 0,124982 ! androgen metabolic process GO:0008209 17 10 0,000 0,07225684 0,12489221 ! phospholipid efflux GO:0033700 16 10 0,000 0,07225684 0,12480255 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,07225684 0,12471303 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,07225684 0,12462363 ! pathogenesis GO:0009405 13 10 0,000 0,07225684 0,12453435 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07225684 0,12444521 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,07225684 0,12435619 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,07225684 0,1242673 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,07225684 0,12417854 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,07225684 0,12408991 ! endoderm development GO:0007492 16 10 0,000 0,07225684 0,1240014 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,07225684 0,12391301 ! arginine catabolic process GO:0006527 13 10 0,000 0,07225684 0,12382476 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,07225684 0,12373663 ! proline metabolic process GO:0006560 13 10 0,000 0,07225684 0,12364862 ! L-serine metabolic process GO:0006563 18 10 0,000 0,07225684 0,12356074 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,07225684 0,12347298 ! V(D)J recombination GO:0033151 28 10 0,000 0,07225684 0,12338535 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07225684 0,12329784 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,07225684 0,12321046 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,07225684 0,1231232 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,07225684 0,12303606 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,07225684 0,12294905 ! multicellular organism growth GO:0035264 18 10 0,000 0,07225684 0,12286216 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,07225684 0,12277539 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,07225684 0,12268875 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,07225684 0,12260223 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,07225684 0,12251583 ! macroautophagy GO:0016236 17 10 0,000 0,07225684 0,12242955 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,07225684 0,12234339 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,07225684 0,12225735 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,07225684 0,12217144 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,07225684 0,12208564 ! copper ion homeostasis GO:0055070 13 10 0,000 0,07225684 0,12199997 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,07225684 0,12191442 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,07225684 0,12182898 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,07225684 0,12174367 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,07225684 0,12165847 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,07225684 0,1215734 ! blastoderm segmentation GO:0007350 18 10 0,000 0,07225684 0,12148844 ! response to dsRNA GO:0043331 20 10 0,000 0,07225684 0,1214036 ! DNA ligation GO:0006266 19 10 0,000 0,07225684 0,12131888 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07225684 0,12123428 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,07225684 0,1211498 ! melanosome localization GO:0032400 16 10 0,000 0,07225684 0,12106543 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,07225684 0,12098118 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,07225684 0,12089705 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,07225684 0,12081304 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,07225684 0,12072914 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,07225684 0,12064536 ! mRNA cleavage GO:0006379 17 10 0,000 0,07225684 0,12056169 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,07225684 0,12047814 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07225684 0,12039471 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,07225684 0,12031139 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,07225684 0,12022819 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,07225684 0,1201451 ! salivary gland development GO:0007431 27 10 0,000 0,07225684 0,12006213 ! prophase GO:0051324 15 10 0,000 0,07225684 0,11997927 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07225684 0,11989652 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,07225684 0,11981389 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,07225684 0,11973138 ! midbrain development GO:0030901 13 10 0,000 0,07225684 0,11964897 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07225684 0,11956668 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,07225684 0,11948451 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,07225684 0,11940244 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,07225684 0,11932049 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,07225684 0,11923865 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,07225684 0,11915693 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,07225684 0,11907531 ! detection of calcium ion GO:0005513 23 10 0,000 0,07225684 0,11899381 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,07225684 0,11891242 ! blastocyst formation GO:0001825 17 10 0,000 0,07225684 0,11883114 ! cerebellar cortex development GO:0021695 15 10 0,000 0,07225684 0,11874997 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,07225684 0,11866891 ! activation of innate immune response GO:0002218 12 10 0,000 0,07225684 0,11858797 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,07225684 0,11850713 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,07225684 0,1184264 ! establishment of cell polarity GO:0030010 16 10 0,000 0,07225684 0,11834579 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,07225684 0,11826528 ! localization within membrane GO:0051668 20 10 0,000 0,07225684 0,11818488 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,07418261 0,12125229 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,07418261 0,12116997 ! viral reproductive process GO:0022415 126 62 1,000 0,07850128 0,12813709 ! gonad development GO:0008406 98 62 1,000 0,07850128 0,12805022 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,07919019 0,12908644 ! respiratory burst GO:0045730 17 11 0,000 0,07919019 0,12899904 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,07919019 0,12891176 ! neuron fate specification GO:0048665 17 11 0,000 0,07919019 0,1288246 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,07919019 0,12873756 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,07919019 0,12865063 ! thyroid gland development GO:0030878 26 11 0,000 0,07919019 0,12856382 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,07919019 0,12847713 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,07919019 0,12839056 ! response to pain GO:0048265 24 11 0,000 0,07919019 0,1283041 ! T cell proliferation GO:0042098 26 11 0,000 0,07919019 0,12821776 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,07919019 0,12813153 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,07919019 0,12804542 ! ventral spinal cord development GO:0021517 21 11 0,000 0,07919019 0,12795943 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07919019 0,12787355 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07919019 0,12778778 ! melanocyte differentiation GO:0030318 21 11 0,000 0,07919019 0,12770214 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,07919019 0,1276166 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,07919019 0,12753118 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,07919019 0,12744588 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,07919019 0,12736069 GO:0043088|regulation of Cdc42 GTPase activity, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,07919019 0,12727561 ! UV protection GO:0009650 19 11 0,000 0,07919019 0,12719064 ! adult heart development GO:0007512 14 11 0,000 0,07919019 0,12710579 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,07919019 0,12702106 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07919019 0,12693643 ! temperature homeostasis GO:0001659 17 11 0,000 0,07919019 0,12685192 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,07919019 0,12676752 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,07919019 0,12668324 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,07919019 0,12659906 ! regulation of organ growth GO:0046620 13 11 0,000 0,07919019 0,126515 ! pigment granule localization GO:0051875 20 11 0,000 0,07919019 0,12643105 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,07919019 0,12634721 ! vasoconstriction GO:0042310 18 11 0,000 0,07919019 0,12626348 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07919019 0,12617986 ! embryonic axis specification GO:0000578 18 11 0,000 0,07919019 0,12609635 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,07919019 0,12601295 ! snRNA metabolic process GO:0016073 24 11 0,000 0,07919019 0,12592967 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07919019 0,12584649 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,07919019 0,12576342 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,07919019 0,12568047 ! zymogen activation GO:0031638 15 11 0,000 0,07919019 0,12559762 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,07919019 0,12551488 ! neuroblast proliferation GO:0007405 24 11 0,000 0,07919019 0,12543225 ! nucleosome positioning GO:0016584 15 11 0,000 0,07919019 0,12534973 ! regulation of isotype switching GO:0045191 22 11 0,000 0,07919019 0,12526731 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,07919019 0,12518501 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,07919019 0,12510281 ! acid secretion GO:0046717 18 11 0,000 0,07919019 0,12502073 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07919019 0,12493874 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,07919019 0,12485687 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,07919019 0,12477511 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,07919019 0,12469345 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,07919019 0,12461189 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,07919019 0,12453045 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,07919019 0,12444911 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07919019 0,12436788 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,07919019 0,12428675 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,07919019 0,12420573 ! embryonic gut development GO:0048566 15 11 0,000 0,07919019 0,12412481 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,07919019 0,124044 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,07919019 0,1239633 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,07919019 0,1238827 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,07919019 0,1238022 ! defense response to fungus GO:0050832 13 11 0,000 0,07919019 0,12372181 ! developmental induction GO:0031128 19 11 0,000 0,07919019 0,12364152 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,07919019 0,12356134 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07919019 0,12348126 ! sequestering of metal ion GO:0051238 14 11 0,000 0,07919019 0,12340129 ! lamellipodium assembly GO:0030032 20 11 0,000 0,07919019 0,12332141 ! nucleus localization GO:0051647 19 11 0,000 0,07919019 0,12324165 ! detection of external stimulus GO:0009581 91 63 1,000 0,08068962 0,125494 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,08068962 0,12541293 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,08289675 0,12876022 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,08289675 0,12867715 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,08607194 0,13351973 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,08607194 0,1334337 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,08607194 0,13334778 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,08607194 0,13326197 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,08607194 0,13317627 ! mating GO:0007618 17 12 0,000 0,08607194 0,13309068 ! protein complex disassembly GO:0043241 27 12 0,000 0,08607194 0,1330052 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,08607194 0,13291983 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,08607194 0,13283457 ! hippocampus development GO:0021766 26 12 0,000 0,08607194 0,13274942 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,08607194 0,13266438 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,08607194 0,13257945 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,08607194 0,13249462 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,08607194 0,13240991 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,08607194 0,1323253 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,08607194 0,1322408 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,08607194 0,13215641 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,08607194 0,13207213 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,08607194 0,13198795 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,08607194 0,13190388 ! polyamine metabolic process GO:0006595 17 12 0,000 0,08607194 0,13181992 ! mitotic spindle organization GO:0007052 21 12 0,000 0,08607194 0,13173607 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,08607194 0,13165232 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,08607194 0,13156868 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,08607194 0,13148514 ! entry into host cell GO:0030260 32 12 0,000 0,08607194 0,13140171 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,08607194 0,13131839 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08607194 0,13123517 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,08607194 0,13115206 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,08607194 0,13106905 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,08607194 0,13098615 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,08607194 0,13090335 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,08607194 0,13082065 ! protein homotetramerization GO:0051289 21 12 0,000 0,08607194 0,13073807 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,08607194 0,13065558 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,08607194 0,1305732 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,08607194 0,13049092 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,08607194 0,13040875 ! cranial nerve development GO:0021545 20 12 0,000 0,08607194 0,13032668 ! fucose catabolic process GO:0019317 22 12 0,000 0,08607194 0,13024471 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,08607194 0,13016285 ! histone methylation GO:0016571 26 12 0,000 0,08607194 0,13008109 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,08607194 0,12999943 ! autonomic nervous system development GO:0048483 24 12 0,000 0,08607194 0,12991788 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,08607194 0,12983642 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,08607194 0,12975507 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,08607194 0,12967382 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,08607194 0,12959268 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,08607194 0,12951163 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,08607194 0,12943068 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,08607194 0,12934984 ! response to cold GO:0009409 17 12 0,000 0,08607194 0,1292691 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,08607194 0,12918846 ! secondary metabolic process GO:0019748 116 66 1,000 0,08736582 0,13104873 ! cell projection assembly GO:0030031 120 66 1,000 0,08736582 0,13096708 ! chromosome segregation GO:0007059 113 67 1,000 0,08962696 0,13427302 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,08962696 0,13418946 ! viral reproduction GO:0016032 134 68 1,000 0,09190533 0,13751507 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0929025 0,1389207 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0929025 0,13883441 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0929025 0,13874824 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0929025 0,13866216 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,0929025 0,1385762 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0929025 0,13849034 ! lipid localization GO:0010876 28 13 0,000 0,0929025 0,13840459 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,0929025 0,13831894 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0929025 0,1382334 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0929025 0,13814796 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0929025 0,13806264 ! endocrine pancreas development GO:0031018 22 13 0,000 0,0929025 0,13797741 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0929025 0,13789229 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0929025 0,13780728 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0929025 0,13772237 ! methionine metabolic process GO:0006555 27 13 0,000 0,0929025 0,13763757 ! plasma membrane organization GO:0007009 24 13 0,000 0,0929025 0,13755287 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,0929025 0,13746827 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,0929025 0,13738378 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0929025 0,13729939 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 22 13 0,000 0,0929025 0,13721511 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,0929025 0,13713092 ! exocrine system development GO:0035272 32 13 0,000 0,0929025 0,13704685 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0929025 0,13696287 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0929025 0,136879 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,0929025 0,13679523 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0929025 0,13671156 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,0929025 0,136628 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,0929025 0,13654454 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,0929025 0,13646118 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0929025 0,13637792 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0929025 0,13629476 ! ribosome assembly GO:0042255 17 13 0,000 0,0929025 0,1362117 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0929025 0,13612875 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,0929025 0,1360459 ! chromatin silencing GO:0006342 26 13 0,000 0,0929025 0,13596314 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,0929025 0,13588049 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0929025 0,13579794 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0929025 0,13571549 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,0929025 0,13563314 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,0929025 0,13555088 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0929025 0,13546873 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,0929025 0,13538668 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0929025 0,13530473 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0929025 0,13522287 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,0929025 0,13514112 ! embryonic placenta development GO:0001892 23 13 0,000 0,0929025 0,13505946 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,0929025 0,1349779 ! insulin secretion GO:0030073 23 13 0,000 0,0929025 0,13489644 ! actin filament polymerization GO:0030041 24 13 0,000 0,0929025 0,13481508 ! acrosome reaction GO:0007340 18 13 0,000 0,0929025 0,13473382 ! amine catabolic process GO:0009310 117 71 1,000 0,09884001 0,14325847 ! rRNA transcription GO:0009303 25 14 0,000 0,09968223 0,14439219 ! lactation GO:0007595 26 14 0,000 0,09968223 0,14430531 ! reproductive cellular process GO:0048610 20 14 0,000 0,09968223 0,14421854 ! tRNA modification GO:0006400 20 14 0,000 0,09968223 0,14413187 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,09968223 0,14404531 ! regulation of S phase GO:0033261 23 14 0,000 0,09968223 0,14395884 ! water transport GO:0006833 21 14 0,000 0,09968223 0,14387249 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,09968223 0,14378623 ! non-recombinational repair GO:0000726 25 14 0,000 0,09968223 0,14370008 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,09968223 0,14361403 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,09968223 0,14352809 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,09968223 0,14344224 ! RNA polyadenylation GO:0043631 30 14 0,000 0,09968223 0,14335651 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,09968223 0,14327087 ! palate development GO:0060021 31 14 0,000 0,09968223 0,14318533 ! regulated secretory pathway GO:0045055 23 14 0,000 0,09968223 0,1430999 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,09968223 0,14301457 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,09968223 0,14292934 ! arginine metabolic process GO:0006525 17 14 0,000 0,09968223 0,14284421 ! regulation of heart rate GO:0002027 24 14 0,000 0,09968223 0,14275919 ! organic alcohol transport GO:0015850 29 14 0,000 0,09968223 0,14267426 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,09968223 0,14258944 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,09968223 0,14250471 ! embryo implantation GO:0007566 30 14 0,000 0,09968223 0,14242009 ! neutral amino acid transport GO:0015804 26 14 0,000 0,09968223 0,14233557 ! L-amino acid transport GO:0015807 30 14 0,000 0,09968223 0,14225115 ! bone mineralization GO:0030282 17 14 0,000 0,09968223 0,14216682 ! stem cell development GO:0048864 43 14 0,000 0,09968223 0,1420826 GO:0019827|stem cell maintenance, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09968223 0,14199848 ! cerebellum development GO:0021549 21 14 0,000 0,09968223 0,14191446 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,09968223 0,14183053 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,09968223 0,14174671 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,09968223 0,14166298 ! cofactor transport GO:0051181 26 14 0,000 0,09968223 0,14157936 ! NADP metabolic process GO:0006739 24 14 0,000 0,09968223 0,14149583 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,09968223 0,1414124 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,09968223 0,14132907 ! oxygen transport GO:0015671 21 14 0,000 0,09968223 0,14124584 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,09968223 0,1411627 ! male genitalia development GO:0030539 24 14 0,000 0,09968223 0,14107967 ! regulation of axon extension GO:0030516 37 14 0,000 0,09968223 0,14099673 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,09968223 0,14091389 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,10118352 0,14295218 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,1035424 0,14619895 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,10591629 0,14946311 GO:0090046|regulation of transcription regulator activity, ! neurotransmitter transport GO:0006836 123 74 1,000 0,10591629 0,1493755 ! exocytosis GO:0006887 133 74 1,000 0,10591629 0,14928799 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,1064115 0,14989817 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,1064115 0,14981046 ! superoxide anion generation GO:0042554 20 15 0,000 0,1064115 0,14972285 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,1064115 0,14963535 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,1064115 0,14954794 ! copper ion transport GO:0006825 20 15 0,000 0,1064115 0,14946064 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,1064115 0,14937344 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,1064115 0,14928634 ! sulfate transport GO:0008272 23 15 0,000 0,1064115 0,14919935 ! response to cAMP GO:0051591 22 15 0,000 0,1064115 0,14911245 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,1064115 0,14902566 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,1064115 0,14893896 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,1064115 0,14885237 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,1064115 0,14876588 ! response to hexose stimulus GO:0009746 22 15 0,000 0,1064115 0,14867949 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,1064115 0,1485932 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,1064115 0,14850701 ! vesicle coating GO:0006901 33 15 0,000 0,1064115 0,14842092 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,1064115 0,14833492 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,1064115 0,14824903 ! regulation of exocytosis GO:0017157 22 15 0,000 0,1064115 0,14816324 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,1064115 0,14807755 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,1064115 0,14799195 ! regulation of vasodilation GO:0042312 26 15 0,000 0,1064115 0,14790646 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,1064115 0,14782106 ! histone deacetylation GO:0016575 20 15 0,000 0,1064115 0,14773576 ! mRNA splice site selection GO:0006376 38 15 0,000 0,1064115 0,14765057 ! tissue regeneration GO:0042246 26 15 0,000 0,1064115 0,14756546 ! water homeostasis GO:0030104 27 15 0,000 0,1064115 0,14748046 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,1064115 0,14739556 ! muscle maintenance GO:0046716 26 15 0,000 0,1064115 0,14731075 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,1064115 0,14722604 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,1064115 0,14714143 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,1064115 0,14705691 ! dopamine metabolic process GO:0042417 35 15 0,000 0,1064115 0,14697249 ! heme biosynthetic process GO:0006783 29 15 0,000 0,1064115 0,14688817 ! cell killing GO:0001906 29 15 0,000 0,1064115 0,14680394 ! detection of bacterium GO:0016045 18 15 0,000 0,1064115 0,14671982 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,1064115 0,14663578 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,1064115 0,14655185 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,1064115 0,14646801 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,1064115 0,14638427 ! peptide hormone processing GO:0016486 23 15 0,000 0,1064115 0,14630062 ! rhythmic process GO:0048511 128 75 1,000 0,10830484 0,14881864 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,11070769 0,15203351 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,11309071 0,15521748 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,11309071 0,15512899 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,11309071 0,1550406 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,11309071 0,1549523 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,11309071 0,15486411 ! bone remodeling GO:0046849 27 16 0,000 0,11309071 0,15477602 ! filopodium assembly GO:0046847 32 16 0,000 0,11309071 0,15468803 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,11309071 0,15460014 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,11309071 0,15451235 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,11309071 0,15442466 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,11309071 0,15433706 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,11309071 0,15424957 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,11309071 0,15416218 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,11309071 0,15407488 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,11309071 0,15398769 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,11309071 0,15390059 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,11309071 0,15381359 ! protein polyubiquitination GO:0000209 34 16 0,000 0,11309071 0,15372669 ! glutamate metabolic process GO:0006536 22 16 0,000 0,11309071 0,15363989 ! response to osmotic stress GO:0006970 25 16 0,000 0,11309071 0,15355319 ! fructose metabolic process GO:0006000 25 16 0,000 0,11309071 0,15346658 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,11309071 0,15338007 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,11309071 0,15329366 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,11309071 0,15320735 ! negative regulation of immune response GO:0050777 35 16 0,000 0,11309071 0,15312113 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,11309071 0,15303501 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,11309071 0,15294899 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,11309071 0,15286306 ! neuron recognition GO:0008038 35 16 0,000 0,11309071 0,15277723 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,11309071 0,1526915 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,11309071 0,15260586 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,11309071 0,15252032 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,11309071 0,15243487 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,11309071 0,15234952 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,11309071 0,15226427 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,11309071 0,15217911 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,11309071 0,15209404 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,11309071 0,15200908 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,11309071 0,1519242 ! neuropeptide signaling pathway GO:0007218 107 77 1,000 0,11312451 0,15188481 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,11312451 0,1518001 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,11972021 0,16056122 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,11972021 0,16047177 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,11972021 0,16038242 ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,11972021 0,16029317 ! signal complex assembly GO:0007172 41 17 0,000 0,11972021 0,16020402 ! endothelial cell migration GO:0043542 28 17 0,000 0,11972021 0,16011497 ! gene silencing by RNA GO:0031047 36 17 0,000 0,11972021 0,16002601 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,11972021 0,15993716 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,11972021 0,1598484 ! adult walking behavior GO:0007628 33 17 0,000 0,11972021 0,15975975 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,11972021 0,15967119 ! heart looping GO:0001947 30 17 0,000 0,11972021 0,15958273 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,11972021 0,15949437 ! myoblast differentiation GO:0045445 45 17 0,000 0,11972021 0,1594061 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,11972021 0,15931793 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,11972021 0,15922986 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,11972021 0,15914189 ! glycine metabolic process GO:0006544 28 17 0,000 0,11972021 0,15905402 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,11972021 0,15896624 ! NAD metabolic process GO:0019674 29 17 0,000 0,11972021 0,15887856 ! membrane budding GO:0006900 37 17 0,000 0,11972021 0,15879097 ! DNA integration GO:0015074 29 17 0,000 0,11972021 0,15870348 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,11972021 0,15861609 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,11972021 0,1585288 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,11972021 0,1584416 ! genitalia development GO:0048806 30 17 0,000 0,11972021 0,15835449 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,11972021 0,15826749 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,11972021 0,15818057 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,11972021 0,15809376 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,11972021 0,15800703 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,11972021 0,15792041 ! steroid catabolic process GO:0006706 31 17 0,000 0,11972021 0,15783388 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,11972021 0,15774744 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,11972021 0,1576611 ! gas transport GO:0015669 25 17 0,000 0,11972021 0,15757485 ! organic cation transport GO:0015695 31 17 0,000 0,11972021 0,1574887 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,11972021 0,15740264 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,11972021 0,15731667 ! microspike assembly GO:0030035 36 17 0,000 0,11972021 0,1572308 ! muscle cell differentiation GO:0042692 159 80 1,000 0,12045537 0,15810999 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,12045537 0,15802378 ! digestion GO:0007586 112 81 1,000 0,12292468 0,16117535 ! response to nutrient GO:0007584 125 82 1,000 0,12540629 0,16433962 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,12630037 0,16542118 ! neuron maturation GO:0042551 42 18 0,000 0,12630037 0,16533117 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,12630037 0,16524127 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,12630037 0,16515147 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,12630037 0,16506176 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,12630037 0,16497215 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,12630037 0,16488264 ! memory GO:0007613 31 18 0,000 0,12630037 0,16479322 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,12630037 0,1647039 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,12630037 0,16461468 ! patterning of blood vessels GO:0001569 39 18 0,000 0,12630037 0,16452555 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,12630037 0,16443653 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,12630037 0,16434759 ! glutamine metabolic process GO:0006541 29 18 0,000 0,12630037 0,16425876 ! response to retinoic acid GO:0032526 26 18 0,000 0,12630037 0,16417002 ! response to fungus GO:0009620 21 18 0,000 0,12630037 0,16408137 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,12630037 0,16399282 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,12630037 0,16390437 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,12630037 0,16381601 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,12630037 0,16372775 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,12630037 0,16363958 ! vitamin transport GO:0051180 27 18 0,000 0,12630037 0,16355151 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,12630037 0,16346353 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,12630037 0,16337564 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,12630037 0,16328786 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,12630037 0,16320016 ! nerve development GO:0021675 28 18 0,000 0,12630037 0,16311256 ! negative regulation of transport GO:0051051 153 84 1,000 0,13040516 0,1683234 ! protein secretion GO:0009306 39 19 0,000 0,13283157 0,17136341 ! positive regulation of translation GO:0045727 30 19 0,000 0,13283157 0,17127157 ! negative regulation of defense response GO:0031348 25 19 0,000 0,13283157 0,17117984 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,13283157 0,1710882 ! skin development GO:0043588 36 19 0,000 0,13283157 0,17099666 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,13283157 0,17090522 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,13283157 0,17081387 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,13283157 0,17072262 ! bile acid metabolic process GO:0008206 29 19 0,000 0,13283157 0,17063148 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,13283157 0,17054042 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,13283157 0,17044947 ! pigmentation during development GO:0048066 41 19 0,000 0,13283157 0,17035861 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,13283157 0,17026785 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,13283157 0,17017718 ! heme metabolic process GO:0042168 36 19 0,000 0,13283157 0,17008662 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,13283157 0,16999615 ! plasma membrane fusion GO:0045026 28 19 0,000 0,13283157 0,16990577 ! peptide cross-linking GO:0018149 37 19 0,000 0,13283157 0,16981549 ! protein export from nucleus GO:0006611 36 19 0,000 0,13283157 0,16972531 ! heart process GO:0003015 30 19 0,000 0,13283157 0,16963522 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,13283157 0,16954523 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,13283157 0,16945533 ! G1 phase GO:0051318 40 19 0,000 0,13283157 0,16936553 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,13283157 0,16927582 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,13283157 0,16918621 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,13283157 0,16909669 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,13283157 0,16900727 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,13283157 0,16891795 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,13283157 0,16882871 ! cilium assembly GO:0042384 37 19 0,000 0,13283157 0,16873957 ! peptide hormone secretion GO:0030072 31 19 0,000 0,13283157 0,16865053 ! response to unfolded protein GO:0006986 131 85 1,000 0,13292179 0,16867607 ! nucleosome assembly GO:0006334 122 85 1,000 0,13292179 0,16858715 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,13292179 0,16849833 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,13292179 0,1684096 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 124 86 1,000 0,13544947 0,1715218 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,13798789 0,17464433 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,13931415 0,17623021 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,13931415 0,1761376 ! positive regulation of ossification GO:0045778 47 20 0,000 0,13931415 0,17604509 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,13931415 0,17595268 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,13931415 0,17586037 ! cAMP metabolic process GO:0046058 36 20 0,000 0,13931415 0,17576815 ! response to vitamin GO:0033273 31 20 0,000 0,13931415 0,17567603 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,13931415 0,175584 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,13931415 0,17549207 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,13931415 0,17540024 ! retinoid metabolic process GO:0001523 32 20 0,000 0,13931415 0,1753085 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,13931415 0,17521686 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,13931415 0,17512532 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,13931415 0,17503387 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,13931415 0,17494251 ! body fluid secretion GO:0007589 31 20 0,000 0,13931415 0,17485126 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,13931415 0,17476009 ! peptide secretion GO:0002790 35 20 0,000 0,13931415 0,17466902 ! stem cell differentiation GO:0048863 53 20 0,000 0,13931415 0,17457805 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,13931415 0,17448717 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,13931415 0,17439639 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,13931415 0,1743057 ! sensory perception of pain GO:0019233 30 20 0,000 0,13931415 0,1742151 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,13931415 0,1741246 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,13931415 0,17403419 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,13931415 0,17394388 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,13931415 0,17385366 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,13931415 0,17376353 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,13931415 0,1736735 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,13931415 0,17358356 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,13931415 0,17349371 ! regulation of glucose import GO:0046324 29 20 0,000 0,13931415 0,17340396 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,13931415 0,1733143 ! actin filament-based movement GO:0030048 43 20 0,000 0,13931415 0,17322473 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,13931415 0,17313526 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,13931415 0,17304587 ! negative regulation of translation GO:0017148 29 20 0,000 0,13931415 0,17295658 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,13931415 0,17286738 ! ossification GO:0001503 188 90 1,000 0,14566467 0,18065422 ! sex differentiation GO:0007548 145 90 1,000 0,14566467 0,18056115 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,14566467 0,18046817 ! regulation of cell killing GO:0031341 42 21 0,000 0,14574849 0,18047909 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,14574849 0,18038625 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,14574849 0,18029351 ! hormone secretion GO:0046879 38 21 0,000 0,14574849 0,18020086 ! glycerol metabolic process GO:0006071 34 21 0,000 0,14574849 0,18010831 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,14574849 0,18001585 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,14574849 0,17992349 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,14574849 0,17983122 ! smooth muscle contraction GO:0006939 46 21 0,000 0,14574849 0,17973905 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,14574849 0,17964697 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,14574849 0,17955498 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,14574849 0,17946309 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,14574849 0,17937129 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,14574849 0,17927959 ! vasodilation GO:0042311 39 21 0,000 0,14574849 0,17918798 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,14574849 0,17909646 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,14574849 0,17900504 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,14574849 0,17891371 ! collagen fibril organization GO:0030199 59 21 0,000 0,14574849 0,17882248 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,14574849 0,17873133 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,14574849 0,17864028 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,14574849 0,17854933 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,14574849 0,17845846 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,14574849 0,17836769 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,14574849 0,17827701 ! collagen catabolic process GO:0030574 28 21 0,000 0,14574849 0,17818642 ! sperm-egg recognition GO:0035036 21 21 0,000 0,14574849 0,17809593 ! bone development GO:0060348 189 91 1,000 0,14824312 0,18105226 ! nucleosome organization GO:0034728 138 92 1,000 0,15083086 0,18411926 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,15213494 0,18561698 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,15213494 0,1855229 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,15213494 0,18542891 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,15213494 0,18533503 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,15213494 0,18524123 ! keratinization GO:0031424 28 22 0,000 0,15213494 0,18514753 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,15213494 0,18505393 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,15213494 0,18496042 ! sensory perception of taste GO:0050909 28 22 0,000 0,15213494 0,18486701 ! lysosome organization GO:0007040 41 22 0,000 0,15213494 0,18477369 ! central nervous system neuron development GO:0021954 46 22 0,000 0,15213494 0,18468046 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,15213494 0,18458733 ! fucose metabolic process GO:0006004 39 22 0,000 0,15213494 0,18449429 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,15213494 0,18440135 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,15213494 0,1843085 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,15213494 0,18421574 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,15213494 0,18412308 ! sarcomere organization GO:0045214 30 22 0,000 0,15213494 0,18403051 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,15213494 0,18393803 ! protein stabilization GO:0050821 39 22 0,000 0,15213494 0,18384564 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,15342761 0,18531467 ! female pregnancy GO:0007565 164 94 1,000 0,15603308 0,18836709 ! transcription initiation GO:0006352 153 94 1,000 0,15603308 0,18827262 ! regulation of T cell activation GO:0050863 158 94 1,000 0,15603308 0,18817825 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,15847386 0,1910261 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,15847386 0,19093045 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,15847386 0,19083489 ! gluconeogenesis GO:0006094 33 23 0,000 0,15847386 0,19073942 ! viral genome replication GO:0019079 41 23 0,000 0,15847386 0,19064405 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,15847386 0,19054878 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,15847386 0,1904536 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,15847386 0,19035851 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,15847386 0,19026352 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,15847386 0,19016863 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,15847386 0,19007383 ! peroxisome organization GO:0007031 37 23 0,000 0,15847386 0,18997913 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,15847386 0,18988451 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,15847386 0,18979 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,15847386 0,18969557 GO:0051693|actin filament capping, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,15847386 0,18960125 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,15847386 0,18950701 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,15847386 0,18941287 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,15847386 0,18931882 ! fatty acid transport GO:0015908 44 23 0,000 0,15847386 0,18922487 ! platelet activation GO:0030168 37 23 0,000 0,15847386 0,189131 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,15847386 0,18903724 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,15847386 0,18894356 ! hormone transport GO:0009914 40 23 0,000 0,15847386 0,18884998 ! cell-cell recognition GO:0009988 25 23 0,000 0,15847386 0,18875649 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,15847386 0,18866309 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,15847386 0,18856978 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,15847386 0,18847657 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,15847386 0,18838345 ! forebrain development GO:0030900 188 95 1,000 0,15864702 0,18849616 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,15864702 0,18840312 ! detection of stimulus GO:0051606 151 96 1,000 0,16126913 0,19142256 ! protein ubiquitination GO:0016567 217 97 1,000 0,16389917 0,19444842 ! hormone metabolic process GO:0042445 157 97 1,000 0,16389917 0,19435258 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,16476559 0,19528375 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,16476559 0,1951876 ! vesicle docking GO:0048278 47 24 0,000 0,16476559 0,19509154 ! spinal cord development GO:0021510 47 24 0,000 0,16476559 0,19499558 ! vacuole organization GO:0007033 43 24 0,000 0,16476559 0,19489971 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,16476559 0,19480394 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,16476559 0,19470826 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,16476559 0,19461267 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,16476559 0,19451718 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,16476559 0,19442178 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,16476559 0,19432648 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,16476559 0,19423126 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,16476559 0,19413615 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,16476559 0,19404112 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,16476559 0,19394619 ! regulation of amine transport GO:0051952 40 24 0,000 0,16476559 0,19385135 ! response to virus GO:0009615 160 98 1,000 0,16653686 0,19583953 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,16653686 0,19574386 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 1,000 0,16918194 0,19875574 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,17101049 0,20080587 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,17101049 0,20070792 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,17101049 0,20061006 ! phototransduction GO:0007602 33 25 0,000 0,17101049 0,2005123 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,17101049 0,20041463 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,17101049 0,20031706 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,17101049 0,20021958 ! receptor metabolic process GO:0043112 46 25 0,000 0,17101049 0,2001222 ! chromosome condensation GO:0030261 45 25 0,000 0,17101049 0,20002491 ! osteoblast differentiation GO:0001649 60 25 0,000 0,17101049 0,19992772 ! neural crest cell development GO:0014032 54 25 0,000 0,17101049 0,19983062 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,17101049 0,19973361 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,17101049 0,1996367 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,17101049 0,19953988 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,17101049 0,19944316 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,17101049 0,19934653 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,17101049 0,19924999 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,17101049 0,19915355 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,17101049 0,1990572 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,17101049 0,19896095 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,17101049 0,19886478 ! telomere organization GO:0032200 43 25 0,000 0,17101049 0,19876871 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,17101049 0,19867274 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,17101049 0,19857685 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,1772089 0,20567517 ! embryonic pattern specification GO:0009880 44 26 0,000 0,1772089 0,205576 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,1772089 0,20547692 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,1772089 0,20537795 ! initiation of viral infection GO:0019059 57 26 0,000 0,1772089 0,20527907 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,1772089 0,20518028 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,1772089 0,20508159 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,1772089 0,20498299 ! tube lumen formation GO:0035148 50 26 0,000 0,1772089 0,20488449 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,1772089 0,20478608 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,1772089 0,20468777 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,1772089 0,20458955 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,1772089 0,20449142 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,1772089 0,20439339 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,1772089 0,20429546 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,1772089 0,20419761 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,1772089 0,20409987 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,1772089 0,20400221 ! blastocyst development GO:0001824 49 26 0,000 0,1772089 0,20390465 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,1772089 0,20380718 ! neuron fate commitment GO:0048663 48 27 0,000 0,18336117 0,21078212 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,18336117 0,21068146 ! iron ion transport GO:0006826 59 27 0,000 0,18336117 0,2105809 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,18336117 0,21048043 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,18336117 0,21038006 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,18336117 0,21027978 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,18336117 0,2101796 ! fat cell differentiation GO:0045444 50 27 0,000 0,18336117 0,21007952 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,18336117 0,20997953 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,18336117 0,20987963 ! autophagy GO:0006914 41 27 0,000 0,18336117 0,20977983 ! primary neural tube formation GO:0014020 51 27 0,000 0,18336117 0,20968013 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,18336117 0,20958051 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,18336117 0,209481 ! glutathione metabolic process GO:0006749 39 27 0,000 0,18336117 0,20938158 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,18336117 0,20928225 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,18336117 0,20918302 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,18336117 0,20908388 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,18946765 0,21594465 ! circadian rhythm GO:0007623 50 28 0,000 0,18946765 0,2158424 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,18946765 0,21574025 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,18946765 0,2156382 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,18946765 0,21553624 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,18946765 0,21543438 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,18946765 0,21533262 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,18946765 0,21523095 ! lipid oxidation GO:0034440 43 28 0,000 0,18946765 0,21512938 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,18946765 0,2150279 ! translational initiation GO:0006413 65 29 0,000 0,19552866 0,22180196 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,19552866 0,22169743 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,19552866 0,221593 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,19552866 0,22148868 ! catechol metabolic process GO:0009712 54 29 0,000 0,19552866 0,22138445 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,19552866 0,22128031 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,19552866 0,22117628 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,19552866 0,22107234 ! cell fate determination GO:0001709 60 29 0,000 0,19552866 0,22096851 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,19552866 0,22086476 ! detection of light stimulus GO:0009583 38 29 0,000 0,19552866 0,22076112 ! regulation of coagulation GO:0050818 46 29 0,000 0,19552866 0,22065757 ! phenol metabolic process GO:0018958 55 30 0,000 0,20154455 0,22733998 ! zinc ion transport GO:0006829 45 30 0,000 0,20154455 0,22723345 ! membrane docking GO:0022406 61 30 0,000 0,20154455 0,22712701 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,20154455 0,22702068 ! regulation of innate immune response GO:0045088 51 30 0,000 0,20154455 0,22691445 ! acute-phase response GO:0006953 49 30 0,000 0,20154455 0,22680831 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,20154455 0,22670228 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,20154455 0,22659634 ! phospholipid transport GO:0015914 51 30 0,000 0,20154455 0,22649051 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,20154455 0,22638477 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,20154455 0,22627913 ! eye morphogenesis GO:0048592 60 30 0,000 0,20154455 0,22617359 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,20751565 0,2327658 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,20751565 0,23265734 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,20751565 0,23254897 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,20751565 0,23244071 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,20751565 0,23233255 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,20751565 0,23222448 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,20751565 0,23211652 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,20751565 0,23200866 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,20751565 0,2319009 ! mesoderm formation GO:0001707 69 31 0,000 0,20751565 0,23179324 ! natural killer cell activation GO:0030101 45 31 0,000 0,20751565 0,23168568 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,20751565 0,23157822 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,20751565 0,23147086 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,20751565 0,2313636 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,20751565 0,23125643 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,20751565 0,23114937 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,21344229 0,23764097 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,21344229 0,23753106 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,21344229 0,23742124 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,21344229 0,23731153 ! spliceosome assembly GO:0000245 67 32 0,000 0,21344229 0,23720191 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,21344229 0,2370924 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,21344229 0,23698299 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,21344229 0,23687368 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,21344229 0,23676447 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,21344229 0,23665537 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,21344229 0,23654636 ! BMP signaling pathway GO:0030509 64 32 0,000 0,21344229 0,23643745 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,21344229 0,23632865 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,21344229 0,23621994 ! gene silencing GO:0016458 65 32 0,000 0,21344229 0,23611133 ! protein targeting to membrane GO:0006612 68 33 0,000 0,2193248 0,24250711 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,2193248 0,24239572 ! ceramide metabolic process GO:0006672 64 33 0,000 0,2193248 0,24228443 ! formation of primary germ layer GO:0001704 72 33 0,000 0,2193248 0,24217323 ! cell fate specification GO:0001708 52 33 0,000 0,2193248 0,24206215 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,2193248 0,24195116 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,2193248 0,24184027 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,22516352 0,24816465 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,22516352 0,24805102 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,22516352 0,2479375 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,22516352 0,24782408 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,22516352 0,24771076 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,22516352 0,24759754 ! mismatch repair GO:0006298 46 34 0,000 0,22516352 0,24748443 ! spermatid development GO:0007286 63 34 0,000 0,22516352 0,24737143 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,22516352 0,24725852 ! negative regulation of secretion GO:0051048 63 35 0,000 0,23095876 0,25350674 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,23095876 0,25339114 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,23095876 0,25327565 ! odontogenesis GO:0042476 66 35 0,000 0,23095876 0,25316026 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,23095876 0,25304498 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,23095876 0,2529298 ! cytokine production GO:0001816 59 35 0,000 0,23095876 0,25281473 ! neural tube formation GO:0001841 67 35 0,000 0,23095876 0,25269976 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,23671085 0,25887559 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,23671085 0,25875797 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,23671085 0,25864046 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,23671085 0,25852306 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,23671085 0,25840576 ! aerobic respiration GO:0009060 55 36 0,000 0,23671085 0,25828857 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,23671085 0,25817149 ! embryonic organ development GO:0048568 57 36 0,000 0,23671085 0,25805451 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,23671085 0,25793763 ! RNA export from nucleus GO:0006405 56 37 0,000 0,2424201 0,26403928 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,2424201 0,2639198 ! organic anion transport GO:0015711 68 37 0,000 0,2424201 0,26380043 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,2424201 0,26368118 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,2424201 0,26356202 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,2424201 0,26344298 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,24808684 0,26947943 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,24808684 0,26935782 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,24808684 0,26923633 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,24808684 0,26911494 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,24808684 0,26899366 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,24808684 0,26887249 ! mRNA catabolic process GO:0006402 71 39 0,000 0,25371138 0,27484447 ! ion transmembrane transport GO:0034220 66 39 0,000 0,25371138 0,27472078 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,25371138 0,2745972 ! RNA modification GO:0009451 57 39 0,000 0,25371138 0,27447373 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,25371138 0,27435037 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,25929403 0,2802612 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,25929403 0,28013535 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,25929403 0,28000962 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,25929403 0,279884 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,25929403 0,27975849 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,2648351 0,28560881 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,2648351 0,28548085 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,2648351 0,285353 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,2648351 0,28522527 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,2648351 0,28509765 ! regulation of tube size GO:0035150 71 42 0,000 0,2703349 0,29088809 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,2703349 0,29075806 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,2703349 0,29062814 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,2703349 0,29049834 ! neuron migration GO:0001764 79 42 0,000 0,2703349 0,29036865 ! regulation of protein secretion GO:0050708 71 42 0,000 0,2703349 0,29023908 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,27579374 0,29596777 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,27579374 0,29583582 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,27579374 0,29570399 ! neural tube development GO:0021915 77 43 0,000 0,27579374 0,29557227 ! striated muscle contraction GO:0006941 77 43 0,000 0,27579374 0,29544067 ! phagocytosis GO:0006909 90 43 0,000 0,27579374 0,29530919 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,27579374 0,29517782 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,28121193 0,30084299 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,28121193 0,30070929 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,28121193 0,3005757 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,28121193 0,30044223 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,28658975 0,3060519 ! glycolysis GO:0006096 65 45 0,000 0,28658975 0,30591612 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,28658975 0,30578046 ! leukocyte migration GO:0050900 68 45 0,000 0,28658975 0,30564492 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,28658975 0,3055095 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,28658975 0,3053742 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,28658975 0,30523902 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,28658975 0,30510395 ! cell growth GO:0016049 84 45 0,000 0,28658975 0,30496901 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,29192752 0,31051176 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,29192752 0,31037455 ! positive regulation of defense response GO:0031349 76 47 0,000 0,29722552 0,31586776 ! response to calcium ion GO:0051592 81 47 0,000 0,29722552 0,3157283 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,29722552 0,31558897 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,29722552 0,31544976 ! protein homooligomerization GO:0051260 76 47 0,000 0,29722552 0,31531067 ! Notch signaling pathway GO:0007219 96 48 0,000 0,30248406 0,32074775 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,30248406 0,32060645 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,30248406 0,32046528 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,30248406 0,32032423 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,30248406 0,3201833 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,30770342 0,32556484 ! regulation of ion transport GO:0043269 77 49 0,000 0,30770342 0,32542173 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,30770342 0,32527875 ! peptide metabolic process GO:0006518 76 49 0,000 0,30770342 0,3251359 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,30770342 0,32499317 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,30770342 0,32485057 ! inner ear development GO:0048839 79 50 0,000 0,31288391 0,33017486 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,31288391 0,33003011 ! viral infectious cycle GO:0019058 99 51 0,000 0,31802579 0,33530677 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,31802579 0,3351599 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,31802579 0,33501316 ! excretion GO:0007588 83 51 0,000 0,31802579 0,33486655 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,31802579 0,33472006 ! chromatin remodeling GO:0006338 109 51 0,000 0,31802579 0,3345737 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,31802579 0,33442747 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,31802579 0,33428137 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,32312937 0,3394975 ! membrane fusion GO:0006944 110 52 0,000 0,32312937 0,33934931 ! amino acid activation GO:0043038 92 52 0,000 0,32312937 0,33920125 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,32819493 0,34436851 ! RNA catabolic process GO:0006401 93 53 0,000 0,32819493 0,34421839 ! regulation of translational initiation GO:0006446 82 53 0,000 0,32819493 0,34406841 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,32819493 0,34391855 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,32819493 0,34376883 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,32819493 0,34361923 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,32819493 0,34346977 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,33322274 0,34857996 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 0,000 0,33322274 0,34842847 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,33322274 0,34827711 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,33322274 0,34812588 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,33322274 0,34797479 ! chloride transport GO:0006821 90 55 0,000 0,33821309 0,35303284 ! glucose catabolic process GO:0006007 82 55 0,000 0,33821309 0,35287974 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,33821309 0,35272678 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,33821309 0,35257396 ! gastrulation GO:0007369 112 55 0,000 0,33821309 0,35242126 ! RNA elongation GO:0006354 79 55 0,000 0,33821309 0,3522687 ! regulation of actin filament length GO:0030832 105 56 0,000 0,34316625 0,35727304 ! sensory perception of smell GO:0007608 80 56 0,000 0,34316625 0,35711852 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,34316625 0,35696412 ! proton transport GO:0015992 94 56 0,000 0,34316625 0,35680986 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,34808251 0,36176524 ! hydrogen transport GO:0006818 97 58 0,000 0,35296213 0,36667828 ! regulation of endocytosis GO:0030100 91 58 0,000 0,35296213 0,36652002 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,35296213 0,3663619 ! positive regulation of secretion GO:0051047 95 59 0,000 0,35780539 0,37122888 ! regulation of cellular component size GO:0032535 109 59 0,000 0,35780539 0,37106887 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,35780539 0,37090899 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,35780539 0,37074926 ! regulation of heart contraction GO:0008016 110 60 0,000 0,36261256 0,37556858 ! camera-type eye development GO:0043010 116 60 0,000 0,36261256 0,37540698 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,36261256 0,37524551 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,3673839 0,38001963 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,3673839 0,37985632 ! mesoderm development GO:0007498 119 61 0,000 0,3673839 0,37969315 ! tRNA processing GO:0008033 89 61 0,000 0,3673839 0,37953012 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,3673839 0,37936723 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,37211968 0,38409264 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,37682016 0,38877758 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,37682016 0,38861094 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,37682016 0,38844444 ! cell redox homeostasis GO:0045454 102 64 0,000 0,38148561 0,39308539 ! single fertilization GO:0007338 75 64 0,000 0,38148561 0,39291712 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,38611629 0,39751639 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,38611629 0,39734636 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,38611629 0,39717648 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,38611629 0,39700675 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,39071245 0,40156094 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,39071245 0,40138948 ! extracellular matrix organization GO:0030198 133 66 0,000 0,39071245 0,40121816 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,39527435 0,40572956 ! hexose catabolic process GO:0019320 104 67 0,000 0,39527435 0,40555654 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,39527435 0,40538367 ! amino acid transport GO:0006865 125 68 0,000 0,39980225 0,40985267 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,39980225 0,40967811 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,39980225 0,40950371 ! regulation of lipase activity GO:0060191 130 68 0,000 0,39980225 0,40932945 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,40429639 0,41375462 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,40429639 0,41357871 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,40429639 0,41340294 ! antigen processing and presentation GO:0019882 104 69 0,000 0,40429639 0,41322732 ! appendage morphogenesis GO:0035107 135 70 0,000 0,40875703 0,4176091 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 0,000 0,41318442 0,42195319 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 137 71 0,000 0,41318442 0,42177417 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,4175788 0,42607913 ! regulation of blood pressure GO:0008217 125 73 0,000 0,42194041 0,43034703 ! fertilization GO:0009566 90 73 0,000 0,42194041 0,43016468 ! transition metal ion transport GO:0000041 126 74 0,000 0,42626951 0,43439409 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,42626951 0,43421018 ! eye development GO:0001654 143 74 0,000 0,42626951 0,43402643 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,43056633 0,43821599 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,43056633 0,43803069 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,43483111 0,44218244 ! defense response to bacterium GO:0042742 89 76 0,000 0,43483111 0,44199563 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,43483111 0,44180898 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,43483111 0,44162248 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,43906409 0,44573342 ! blood coagulation GO:0007596 146 78 0,000 0,44326551 0,44980887 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,44326551 0,44961923 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,4474356 0,45365784 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,4474356 0,45346674 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,4474356 0,45327581 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,4474356 0,45308504 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,45157459 0,45708391 ! inorganic anion transport GO:0015698 138 80 0,000 0,45157459 0,4568917 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,45568271 0,4608544 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,45568271 0,46066076 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,4597602 0,46458759 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,4597602 0,46439254 ! regulation of lyase activity GO:0051339 160 83 0,000 0,46380728 0,46828381 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,46782417 0,47214134 ! hemostasis GO:0007599 158 84 0,000 0,46782417 0,47194338 ! amine biosynthetic process GO:0009309 138 86 0,000 0,4757683 0,4797563 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,4757683 0,47955531 ! alcohol catabolic process GO:0046164 130 86 0,000 0,4757683 0,47935449 ! amine transport GO:0015837 155 86 0,000 0,4757683 0,47915384 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,47969598 0,48290733 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,48359436 0,4866282 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,48359436 0,48642476 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,48359436 0,48622149 ! cellular defense response GO:0006968 114 89 0,000 0,48746366 0,48990709 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,4913041 0,49356061 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,49511589 0,49718232 ! regulation of defense response GO:0031347 149 92 0,000 0,49889924 0,50077245 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,49889924 0,50056362 ! vitamin metabolic process GO:0006766 139 92 0,000 0,49889924 0,50035497 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,50265437 0,503911 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,50638148 0,507436 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,51375248 0,51460802 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,51375248 0,51439387 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,51739679 0,51782723 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,5210139 0,52123054 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,52460402 0,52460402