pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6561-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 67 40 7,000 2,329E-10 5,357E-07 ! DNA ligation during DNA repair GO:0051103 9 6 3,000 3,029E-08 3,484E-05 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 3,000 3,029E-08 2,323E-05 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 3,000 1,399E-07 8,044E-05 ! DNA ligation GO:0006266 14 9 3,000 2,505E-07 1,152E-04 ! base-excision repair GO:0006284 31 24 4,000 5,147E-07 1,973E-04 ! response to UV GO:0009411 75 46 5,000 6,572E-07 2,159E-04 ! DNA unwinding during replication GO:0006268 21 14 3,000 1,938E-06 5,572E-04 ! DNA damage response, signal transduction GO:0042770 96 56 5,000 2,155E-06 5,508E-04 ! microvillus organization GO:0032528 7 5 2,000 3,045E-06 7,003E-04 GO:0030033|microvillus assembly, ! DNA duplex unwinding GO:0032508 25 17 3,000 4,536E-06 9,484E-04 GO:0032392|DNA geometric change, ! regulation of helicase activity GO:0051095 11 6 2,000 6,06E-06 1,161E-03 ! response to interferon-gamma GO:0034341 12 6 2,000 6,06E-06 1,072E-03 ! ER overload response GO:0006983 7 6 2,000 6,06E-06 9,955E-04 ! negative regulation of DNA recombination GO:0045910 9 6 2,000 6,06E-06 9,291E-04 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 2,000 6,06E-06 8,711E-04 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 2,000 1,055E-05 1,428E-03 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 2,000 1,055E-05 1,348E-03 GO:0016446|somatic hypermutation of immunoglobulin genes, ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,055E-05 1,277E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 3,000 1,117E-05 1,284E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 3,000 1,358E-05 1,487E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 3,000 1,635E-05 1,71E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 3,000 1,635E-05 1,635E-03 ! negative regulation of phosphorylation GO:0042326 41 23 3,000 1,635E-05 1,567E-03 ! induction of positive chemotaxis GO:0050930 14 8 2,000 1,68E-05 1,545E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 1,68E-05 1,486E-03 ! insulin receptor signaling pathway GO:0008286 40 24 3,000 1,952E-05 1,663E-03 ! ear development GO:0043583 72 50 4,000 2,228E-05 1,83E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 2,312E-05 1,833E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of DNA metabolic process GO:0051052 135 85 5,000 2,473E-05 1,896E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 2,507E-05 1,86E-03 ! DNA recombination GO:0006310 146 92 5,000 3,879E-05 2,788E-03 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 4,239E-05 2,954E-03 ! regulation of positive chemotaxis GO:0050926 17 11 2,000 4,876E-05 3,299E-03 GO:0050927|positive regulation of positive chemotaxis, ! chondrocyte differentiation GO:0002062 17 11 2,000 4,876E-05 3,204E-03 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 2,000 4,876E-05 3,115E-03 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! negative regulation of glucose import GO:0046325 14 11 2,000 4,876E-05 3,031E-03 GO:0010829|negative regulation of glucose transport, ! response to light stimulus GO:0009416 153 96 5,000 4,932E-05 2,985E-03 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 5,000 5,864E-05 3,458E-03 ! negative regulation of DNA metabolic process GO:0051053 48 32 3,000 6,334E-05 3,642E-03 ! meiosis I GO:0007127 52 32 3,000 6,334E-05 3,553E-03 ! auditory receptor cell differentiation GO:0042491 25 12 2,000 6,469E-05 3,543E-03 ! immunoglobulin production during immune response GO:0002381 20 12 2,000 6,469E-05 3,46E-03 ! cellular response to insulin stimulus GO:0032869 52 34 3,000 8,083E-05 4,225E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 8,368E-05 4,277E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,06E-04 5,299E-03 ! positive regulation of phosphorylation GO:0042327 102 70 4,000 1,142E-04 5,588E-03 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 4,000 1,306E-04 6,258E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,318E-04 6,187E-03 ! inner ear development GO:0048839 57 40 3,000 1,543E-04 7,1E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 1,614E-04 7,28E-03 ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 2,000 1,614E-04 7,14E-03 ! inner ear receptor cell differentiation GO:0060113 30 16 2,000 1,614E-04 7,005E-03 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 2,000 1,95E-04 8,308E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 1,95E-04 8,157E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 1,95E-04 8,011E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 2,052E-04 8,279E-03 ! DNA-dependent DNA replication GO:0006261 59 43 3,000 2,052E-04 8,136E-03 ! response to insulin stimulus GO:0032868 63 43 3,000 2,052E-04 7,998E-03 ! induction of apoptosis by extracellular signals GO:0008624 74 44 3,000 2,245E-04 8,606E-03 ! mechanoreceptor differentiation GO:0042490 32 18 2,000 2,329E-04 8,781E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 2,329E-04 8,64E-03 ! regulation of glucose import GO:0046324 21 18 2,000 2,329E-04 8,503E-03 GO:0010827|regulation of glucose transport, ! positive regulation of cell cycle GO:0045787 77 45 3,000 2,451E-04 8,809E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 2,451E-04 8,674E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 2,752E-04 9,59E-03 ! somatic diversification of immunoglobulins GO:0016445 29 19 2,000 2,752E-04 9,447E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 3,222E-04 0,01089646 ! positive regulation of locomotion GO:0040017 35 20 2,000 3,222E-04 0,01073854 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 2,000 3,222E-04 0,01058513 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 2,000 3,74E-04 0,01211509 GO:0016444|somatic cell DNA recombination, ! regulation of chemotaxis GO:0050920 36 21 2,000 3,74E-04 0,01194682 ! dendrite development GO:0016358 35 21 2,000 3,74E-04 0,01178317 ! regulation of DNA recombination GO:0000018 40 21 2,000 3,74E-04 0,01162394 ! immunoglobulin production GO:0002377 33 21 2,000 3,74E-04 0,01146895 GO:0002440|production of molecular mediator of immune response, ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 3,74E-04 0,01131804 ! response to cytokine stimulus GO:0034097 47 21 2,000 3,74E-04 0,01117106 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 3,984E-04 0,01174819 ! negative regulation of cell motion GO:0051271 104 51 3,000 3,984E-04 0,01159947 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 4,309E-04 0,0123882 ! regulation of behavior GO:0050795 38 22 2,000 4,309E-04 0,01223526 ! neural tube closure GO:0001843 33 22 2,000 4,309E-04 0,01208605 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! protein tetramerization GO:0051262 39 22 2,000 4,309E-04 0,01194044 ! peptidyl-amino acid modification GO:0018193 147 93 4,000 4,331E-04 0,01185757 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 4,534E-04 0,01226752 ! positive regulation of glycolysis GO:0045821 11 5 1,000 4,534E-04 0,01212487 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 4,534E-04 0,01198551 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 1,000 4,534E-04 0,01184931 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 1,000 4,534E-04 0,01171617 ! establishment of planar polarity GO:0001736 6 5 1,000 4,534E-04 0,01158599 ! regulation of respiratory burst GO:0060263 8 5 1,000 4,534E-04 0,01145867 ! determination of adult lifespan GO:0008340 8 5 1,000 4,534E-04 0,01133412 ! spindle assembly GO:0051225 5 5 1,000 4,534E-04 0,01121225 ! myelination GO:0042552 35 23 2,000 4,931E-04 0,01206461 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 4,931E-04 0,01193762 ! somatic diversification of immune receptors GO:0002200 35 23 2,000 4,931E-04 0,01181327 ! regulation of cellular catabolic process GO:0031329 36 24 2,000 5,607E-04 0,01329557 ! primary neural tube formation GO:0014020 35 24 2,000 5,607E-04 0,0131599 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 6,103E-04 0,01417891 ! chromosome segregation GO:0007059 83 57 3,000 6,103E-04 0,01403712 ! regulation of chromosome organization GO:0033044 35 25 2,000 6,34E-04 0,01443846 ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 6,34E-04 0,01429691 ! negative regulation of kinase activity GO:0033673 100 58 3,000 6,521E-04 0,01456146 ! male meiosis GO:0007140 7 6 1,000 6,77E-04 0,0149725 ! meiotic prophase I GO:0007128 9 6 1,000 6,77E-04 0,0148299 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 6,77E-04 0,01469 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 6,77E-04 0,01455271 ! establishment of tissue polarity GO:0007164 7 6 1,000 6,77E-04 0,01441796 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 6,77E-04 0,01428569 ! male sex determination GO:0030238 9 6 1,000 6,77E-04 0,01415582 ! dendrite morphogenesis GO:0048813 9 6 1,000 6,77E-04 0,01402829 ! establishment of chromosome localization GO:0051303 9 6 1,000 6,77E-04 0,01390304 GO:0050000|chromosome localization, ! receptor internalization GO:0031623 9 6 1,000 6,77E-04 0,01378 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 6,77E-04 0,01365912 ! lung development GO:0030324 94 59 3,000 6,959E-04 0,01391759 ! regulation of pH GO:0006885 36 26 2,000 7,132E-04 0,01414089 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 7,132E-04 0,01402003 ! negative regulation of protein modification process GO:0031400 50 26 2,000 7,132E-04 0,01390122 ! meiosis GO:0007126 96 61 3,000 7,896E-04 0,01526143 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of transferase activity GO:0051348 105 61 3,000 7,896E-04 0,01513425 ! negative regulation of transcription regulator activity GO:0090048 47 27 2,000 7,984E-04 0,01517573 GO:0043433|negative regulation of transcription factor activity, ! respiratory tube development GO:0030323 99 62 3,000 8,397E-04 0,01582988 ! meiotic cell cycle GO:0051321 97 62 3,000 8,397E-04 0,01570118 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 8,898E-04 0,01650363 ! ensheathment of neurons GO:0007272 43 28 2,000 8,898E-04 0,0163716 GO:0008366|axon ensheathment, ! neural tube formation GO:0001841 41 28 2,000 8,898E-04 0,01624167 ! regulation of transcription factor activity GO:0051090 97 63 3,000 8,919E-04 0,01615305 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 8,919E-04 0,01602685 ! negative regulation of cellular catabolic process GO:0031330 9 7 1,000 9,436E-04 0,01682394 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 9,436E-04 0,01669453 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 9,436E-04 0,01656709 ! microtubule bundle formation GO:0001578 8 7 1,000 9,436E-04 0,01644158 ! central nervous system neuron axonogenesis GO:0021955 14 7 1,000 9,436E-04 0,01631796 GO:0021952|central nervous system projection neuron axonogenesis, ! protein heterooligomerization GO:0051291 10 7 1,000 9,436E-04 0,01619618 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 9,436E-04 0,01607621 ! B cell lineage commitment GO:0002326 17 7 1,000 9,436E-04 0,015958 ! multicellular organismal aging GO:0010259 11 7 1,000 9,436E-04 0,01584152 ! T cell lineage commitment GO:0002360 12 7 1,000 9,436E-04 0,01572673 ! response to tumor cell GO:0002347 12 7 1,000 9,436E-04 0,01561359 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 3,000 9,464E-04 0,0155486 ! respiratory system development GO:0060541 100 64 3,000 9,464E-04 0,01543833 ! mismatch repair GO:0006298 34 29 2,000 9,875E-04 0,01599508 ! B cell activation GO:0042113 104 65 3,000 1,003E-03 0,01613615 ! spindle organization GO:0007051 37 30 2,000 1,092E-03 0,0174389 ! embryonic epithelial tube formation GO:0001838 44 30 2,000 1,092E-03 0,01731863 ! leukocyte chemotaxis GO:0030595 43 31 2,000 1,203E-03 0,01894884 GO:0060326|cell chemotaxis, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,253E-03 0,01959754 ! axon extension GO:0048675 11 8 1,000 1,253E-03 0,01946513 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 1,253E-03 0,01933449 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,253E-03 0,01920559 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,253E-03 0,0190784 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,253E-03 0,01895289 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,253E-03 0,01882901 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,253E-03 0,01870675 ! oligodendrocyte development GO:0014003 8 8 1,000 1,253E-03 0,01858606 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 1,253E-03 0,01846692 ! morphogenesis of a polarized epithelium GO:0001738 9 8 1,000 1,253E-03 0,01834929 ! prophase GO:0051324 11 8 1,000 1,253E-03 0,01823316 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,253E-03 0,01811848 ! regulation of embryonic development GO:0045995 16 8 1,000 1,253E-03 0,01800524 ! mitotic sister chromatid segregation GO:0000070 45 32 2,000 1,321E-03 0,01886741 ! monovalent inorganic cation homeostasis GO:0055067 45 32 2,000 1,321E-03 0,01875095 ! calcium-mediated signaling GO:0019722 50 32 2,000 1,321E-03 0,01863591 ! sister chromatid segregation GO:0000819 46 33 2,000 1,446E-03 0,02027396 ! ear morphogenesis GO:0042471 42 33 2,000 1,446E-03 0,02015109 ! negative regulation of DNA binding GO:0043392 54 33 2,000 1,446E-03 0,02002969 ! cytokinesis GO:0000910 52 33 2,000 1,446E-03 0,01990976 ! neuron migration GO:0001764 46 34 2,000 1,578E-03 0,02159944 ! regulation of developmental growth GO:0048638 13 9 1,000 1,603E-03 0,02181929 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 1,603E-03 0,02169094 ! regulation of glycolysis GO:0006110 15 9 1,000 1,603E-03 0,02156409 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 1,603E-03 0,02143872 ! L-serine metabolic process GO:0006563 13 9 1,000 1,603E-03 0,0213148 ! motor axon guidance GO:0008045 14 9 1,000 1,603E-03 0,0211923 ! localization within membrane GO:0051668 15 9 1,000 1,603E-03 0,0210712 ! cellular response to hormone stimulus GO:0032870 109 74 3,000 1,627E-03 0,02125985 ! regulation of action potential in neuron GO:0019228 54 35 2,000 1,717E-03 0,02231256 ! negative regulation of binding GO:0051100 58 36 2,000 1,864E-03 0,02408489 ! neural tube development GO:0021915 50 36 2,000 1,864E-03 0,02395033 ! regulation of DNA binding GO:0051101 119 77 3,000 1,884E-03 0,02406943 ! positive regulation of protein modification process GO:0031401 107 78 3,000 1,975E-03 0,02509929 ! negative regulation of muscle development GO:0048635 12 10 1,000 1,995E-03 0,02521336 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,995E-03 0,02507558 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,995E-03 0,0249393 ! response to X-ray GO:0010165 16 10 1,000 1,995E-03 0,02480449 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 1,995E-03 0,02467114 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 1,995E-03 0,0245392 GO:0043470|regulation of carbohydrate catabolic process, ! morphogenesis of embryonic epithelium GO:0016331 60 39 2,000 2,351E-03 0,02875884 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 2,351E-03 0,02860668 ! virus-host interaction GO:0019048 17 11 1,000 2,428E-03 0,02938763 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,428E-03 0,02923376 ! detection of mechanical stimulus GO:0050982 15 11 1,000 2,428E-03 0,0290815 ! negative regulation of proteolysis GO:0045861 16 11 1,000 2,428E-03 0,02893082 ! oligodendrocyte differentiation GO:0048709 14 11 1,000 2,428E-03 0,02878169 ! focal adhesion formation GO:0048041 24 11 1,000 2,428E-03 0,0286341 ! regulation of intracellular pH GO:0051453 17 11 1,000 2,428E-03 0,028488 ! serine family amino acid biosynthetic process GO:0009070 13 11 1,000 2,428E-03 0,02834339 ! digestive tract morphogenesis GO:0048546 15 11 1,000 2,428E-03 0,02820025 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 2,428E-03 0,02805854 GO:0042130|negative regulation of T cell proliferation, ! acrosome reaction GO:0007340 13 11 1,000 2,428E-03 0,02791824 ! positive regulation of response to external stimulus GO:0032103 65 40 2,000 2,529E-03 0,0289366 ! double-strand break repair GO:0006302 67 40 2,000 2,529E-03 0,02879335 ! microtubule cytoskeleton organization GO:0000226 120 84 3,000 2,59E-03 0,0293415 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 2,703E-03 0,03048063 ! cell cycle arrest GO:0007050 150 86 3,000 2,821E-03 0,03164662 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 2,821E-03 0,03149299 ! reproductive cellular process GO:0048610 14 12 1,000 2,9E-03 0,03222522 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 2,9E-03 0,03207029 ! non-recombinational repair GO:0000726 19 12 1,000 2,9E-03 0,03191684 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 2,9E-03 0,03176486 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 2,9E-03 0,03161431 ! peptidyl-lysine modification GO:0018205 18 12 1,000 2,9E-03 0,03146519 ! response to gamma radiation GO:0010332 20 12 1,000 2,9E-03 0,03131746 ! receptor-mediated endocytosis GO:0006898 76 42 2,000 2,909E-03 0,03127007 ! interphase GO:0051325 159 88 3,000 3,065E-03 0,03279242 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 3,112E-03 0,03314022 ! leukocyte migration GO:0050900 60 43 2,000 3,112E-03 0,0329875 ! activation of caspase activity GO:0006919 65 43 2,000 3,112E-03 0,03283618 ! epithelial tube morphogenesis GO:0060562 65 43 2,000 3,112E-03 0,03268625 ! regulation of action potential GO:0001508 71 44 2,000 3,324E-03 0,03474673 ! regulation of inflammatory response GO:0050727 60 44 2,000 3,324E-03 0,03458951 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 3,324E-03 0,0344337 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 3,412E-03 0,03519491 ! response to hexose stimulus GO:0009746 19 13 1,000 3,412E-03 0,03503779 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! regulation of cellular pH GO:0030641 20 13 1,000 3,412E-03 0,03488207 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 3,412E-03 0,03472772 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 1,000 3,412E-03 0,03457473 ! positive regulation of defense response GO:0031349 59 45 2,000 3,543E-03 0,03574575 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 3,963E-03 0,0398075 ! cellular response to starvation GO:0009267 21 14 1,000 3,963E-03 0,03963442 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 3,963E-03 0,03946285 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 3,963E-03 0,03929275 ! G1/S transition checkpoint GO:0031575 33 14 1,000 3,963E-03 0,03912411 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 4,009E-03 0,0394093 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of binding GO:0051098 151 95 3,000 4,036E-03 0,03949689 ! regulation of cellular component biogenesis GO:0044087 158 96 3,000 4,189E-03 0,04082716 ! positive regulation of caspase activity GO:0043280 72 48 2,000 4,256E-03 0,04130059 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 2,000 4,256E-03 0,04112706 ! regulation of DNA replication GO:0006275 75 48 2,000 4,256E-03 0,04095498 ! immunoglobulin mediated immune response GO:0016064 66 48 2,000 4,256E-03 0,04078434 GO:0019724|B cell mediated immunity, ! cartilage development GO:0051216 70 49 2,000 4,511E-03 0,04305146 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 4,553E-03 0,04327159 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 4,553E-03 0,04309351 ! lipid phosphorylation GO:0046834 23 15 1,000 4,553E-03 0,0429169 ! regulation of neurotransmitter secretion GO:0046928 26 15 1,000 4,553E-03 0,04274173 ! regulation of survival gene product expression GO:0045884 20 15 1,000 4,553E-03 0,04256798 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 4,553E-03 0,04239564 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 4,553E-03 0,04222469 ! dopamine metabolic process GO:0042417 30 15 1,000 4,553E-03 0,04205512 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 4,553E-03 0,0418869 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 4,553E-03 0,04172002 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 4,553E-03 0,04155446 ! positive regulation of cell migration GO:0030335 92 51 2,000 5,049E-03 0,04589988 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 5,18E-03 0,04690805 ! endothelial cell migration GO:0043542 22 16 1,000 5,18E-03 0,04672409 ! protein amino acid acetylation GO:0006473 28 16 1,000 5,18E-03 0,04654158 ! glial cell development GO:0021782 24 16 1,000 5,18E-03 0,04636048 ! mitotic chromosome condensation GO:0007076 25 16 1,000 5,18E-03 0,04618079 ! cellular response to unfolded protein GO:0034620 19 16 1,000 5,18E-03 0,04600249 GO:0030968|endoplasmic reticulum unfolded protein response, ! fructose metabolic process GO:0006000 20 16 1,000 5,18E-03 0,04582555 ! oogenesis GO:0048477 23 16 1,000 5,18E-03 0,04564998 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 5,18E-03 0,04547574 ! negative regulation of translation GO:0017148 22 16 1,000 5,18E-03 0,04530283 ! aging GO:0007568 79 52 2,000 5,332E-03 0,04645147 ! establishment of organelle localization GO:0051656 85 52 2,000 5,332E-03 0,04627618 ! cell projection assembly GO:0030031 76 53 2,000 5,624E-03 0,04862866 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 5,845E-03 0,05034999 ! forelimb morphogenesis GO:0035136 19 17 1,000 5,845E-03 0,05016212 ! cell-substrate junction assembly GO:0007044 39 17 1,000 5,845E-03 0,04997564 ! actin filament bundle formation GO:0051017 26 17 1,000 5,845E-03 0,04979055 ! neuromuscular junction development GO:0007528 23 17 1,000 5,845E-03 0,04960682 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 5,845E-03 0,04942444 ! peptidyl-serine modification GO:0018209 27 17 1,000 5,845E-03 0,0492434 ! regulation of mitosis GO:0007088 84 54 2,000 5,926E-03 0,04974076 GO:0051783|regulation of nuclear division, ! cytokine-mediated signaling pathway GO:0019221 76 54 2,000 5,926E-03 0,04955988 ! positive regulation of DNA replication GO:0045740 29 18 1,000 6,546E-03 0,05455406 ! response to carbohydrate stimulus GO:0009743 24 18 1,000 6,546E-03 0,05435711 ! central nervous system neuron development GO:0021954 30 18 1,000 6,546E-03 0,05416159 ! somitogenesis GO:0001756 24 18 1,000 6,546E-03 0,05396746 ! cellular response to nutrient levels GO:0031669 27 18 1,000 6,546E-03 0,05377472 ! gut development GO:0048565 26 18 1,000 6,546E-03 0,05358335 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 6,546E-03 0,05339334 ! negative regulation of T cell activation GO:0050868 25 18 1,000 6,546E-03 0,05320467 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 6,546E-03 0,05301733 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 6,558E-03 0,05292031 ! positive regulation of cell motion GO:0051272 99 56 2,000 6,558E-03 0,05273528 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 7,284E-03 0,05837581 ! reciprocal meiotic recombination GO:0007131 31 19 1,000 7,284E-03 0,05817312 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 7,284E-03 0,05797183 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 7,284E-03 0,05777193 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 32 19 1,000 7,284E-03 0,0575734 ! vesicle docking during exocytosis GO:0006904 24 19 1,000 7,284E-03 0,05737623 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 7,284E-03 0,0571804 ! apoptotic nuclear changes GO:0030262 24 19 1,000 7,284E-03 0,05698591 ! response to starvation GO:0042594 30 19 1,000 7,284E-03 0,05679274 ! sex determination GO:0007530 29 19 1,000 7,284E-03 0,05660087 ! plasma membrane fusion GO:0045026 23 19 1,000 7,284E-03 0,0564103 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 7,284E-03 0,056221 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 7,284E-03 0,05603297 ! regulation of heart contraction GO:0008016 91 60 2,000 7,938E-03 0,06085643 ! hindlimb morphogenesis GO:0035137 32 20 1,000 8,058E-03 0,06157166 ! regulation of neurotransmitter transport GO:0051588 35 20 1,000 8,058E-03 0,06136778 ! central nervous system neuron differentiation GO:0021953 33 20 1,000 8,058E-03 0,06116524 ! chromosome condensation GO:0030261 31 20 1,000 8,058E-03 0,06096404 ! positive regulation of B cell activation GO:0050871 31 20 1,000 8,058E-03 0,06076416 ! negative regulation of cell growth GO:0030308 106 62 2,000 8,687E-03 0,06529633 ! lymphocyte mediated immunity GO:0002449 88 62 2,000 8,687E-03 0,06508364 ! organelle localization GO:0051640 96 62 2,000 8,687E-03 0,06487232 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 8,867E-03 0,06599798 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 8,867E-03 0,06578508 ! protein amino acid acylation GO:0043543 37 21 1,000 8,867E-03 0,06557355 ! vesicle docking GO:0048278 27 21 1,000 8,867E-03 0,06536338 ! ovarian follicle development GO:0001541 30 21 1,000 8,867E-03 0,06515455 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 8,867E-03 0,06494705 ! cell aging GO:0007569 32 21 1,000 8,867E-03 0,06474087 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 8,867E-03 0,06453599 ! acetyl-CoA catabolic process GO:0046356 31 21 1,000 8,867E-03 0,06433241 GO:0006099|tricarboxylic acid cycle, ! negative regulation of cell size GO:0045792 108 64 2,000 9,477E-03 0,06854348 ! adaptive immune response GO:0002250 94 64 2,000 9,477E-03 0,06832861 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! protein import into nucleus, translocation GO:0000060 36 22 1,000 9,71E-03 0,06979252 ! coenzyme catabolic process GO:0009109 33 22 1,000 9,71E-03 0,0695751 ! regulation of caspase activity GO:0043281 97 65 2,000 9,887E-03 0,07062068 ! protein oligomerization GO:0051259 100 65 2,000 9,887E-03 0,07040204 ! regulation of Rho protein signal transduction GO:0035023 111 66 2,000 0,01030711 0,07316775 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01058809 0,07493111 ! acetyl-CoA metabolic process GO:0006084 33 23 1,000 0,01058809 0,07470126 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01058809 0,07447281 ! negative regulation of DNA replication GO:0008156 35 23 1,000 0,01058809 0,07424576 ! interaction with host GO:0051701 37 23 1,000 0,01058809 0,07402009 ! negative regulation of catabolic process GO:0009895 34 23 1,000 0,01058809 0,07379579 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01073757 0,0746115 ! fat cell differentiation GO:0045444 37 24 1,000 0,01149967 0,07966639 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01149967 0,07942715 ! receptor metabolic process GO:0043112 37 24 1,000 0,01149967 0,07918934 ! negative regulation of cell development GO:0010721 56 24 1,000 0,01149967 0,07895296 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,01149967 0,07871798 ! regulation of catabolic process GO:0009894 106 70 2,000 0,01209084 0,08251912 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01244451 0,08468156 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01244451 0,08443176 GO:0045840|positive regulation of mitosis, ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 0,01244451 0,08418343 ! leukocyte mediated immunity GO:0002443 99 71 2,000 0,0125627 0,08473377 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,013045 0,08772954 ! negative regulation of organelle organization GO:0010639 115 72 2,000 0,013045 0,08747377 ! regulation of synaptic transmission GO:0050804 109 72 2,000 0,013045 0,08721948 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,01342212 0,08948078 ! negative regulation of transport GO:0051051 116 73 2,000 0,01353778 0,08999099 ! tube morphogenesis GO:0035239 118 73 2,000 0,01353778 0,08973165 ! mitochondrion organization GO:0007005 104 73 2,000 0,01353778 0,0894738 ! membrane docking GO:0022406 39 27 1,000 0,01443202 0,09511071 ! inner ear morphogenesis GO:0042472 35 27 1,000 0,01443202 0,09483896 ! catechol metabolic process GO:0009712 43 27 1,000 0,01443202 0,09456877 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to ionizing radiation GO:0010212 47 27 1,000 0,01443202 0,0943001 ! cofactor catabolic process GO:0051187 45 27 1,000 0,01443202 0,09403297 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 0,01443202 0,09376734 ! serine family amino acid metabolic process GO:0009069 37 27 1,000 0,01443202 0,0935032 ! negative regulation of growth GO:0045926 123 75 2,000 0,01455487 0,09403425 ! phenol metabolic process GO:0018958 44 28 1,000 0,01547373 0,09969068 ! cell junction assembly GO:0034329 56 28 1,000 0,01547373 0,09941222 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 1,000 0,01547373 0,0991353 ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,01547373 0,09885993 ! regulation of B cell activation GO:0050864 42 28 1,000 0,01547373 0,09858608 ! regulation of transmission of nerve impulse GO:0051969 116 77 2,000 0,01561419 0,09920619 ! ovulation cycle process GO:0022602 41 29 1,000 0,01654678 0,10484186 ! ovulation cycle GO:0042698 43 30 1,000 0,01765071 0,11152918 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,01765071 0,11122362 ! negative regulation of cell activation GO:0050866 44 30 1,000 0,01765071 0,11091973 ! response to heat GO:0009408 41 30 1,000 0,01765071 0,1106175 ! regulation of cell cycle process GO:0010564 122 81 2,000 0,01786025 0,11162655 ! regulation of neurological system process GO:0031644 122 81 2,000 0,01786025 0,11132404 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,01878504 0,11677188 ! mammary gland development GO:0030879 57 31 1,000 0,01878504 0,11645713 ! glial cell differentiation GO:0010001 55 31 1,000 0,01878504 0,11614407 ! segmentation GO:0035282 41 31 1,000 0,01878504 0,11583269 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,01878504 0,11552298 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01878504 0,11521492 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,01878504 0,1149085 ! regulation of defense response GO:0031347 117 84 2,000 0,01965679 0,11992206 ! regulation of muscle development GO:0048634 48 32 1,000 0,01994933 0,12138481 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 0,01994933 0,12106453 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01994933 0,12074594 ! regulation of protein stability GO:0031647 48 32 1,000 0,01994933 0,12042902 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,01994933 0,12011376 ! Golgi vesicle transport GO:0048193 138 85 2,000 0,02027703 0,12176808 ! rRNA metabolic process GO:0016072 107 85 2,000 0,02027703 0,12145097 GO:0006364|rRNA processing, ! regulation of membrane potential GO:0042391 128 85 2,000 0,02027703 0,12113552 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,02114312 0,1259823 ! cell junction organization GO:0034330 63 33 1,000 0,02114312 0,12565677 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,02114312 0,12533291 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 0,02114312 0,12501072 ! female gonad development GO:0008585 49 33 1,000 0,02114312 0,12469018 ! regulation of proteolysis GO:0030162 50 33 1,000 0,02114312 0,12437128 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,02114312 0,124054 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,02114312 0,12373834 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,02154965 0,12579746 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 0,02154965 0,12547899 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,02236596 0,12990328 ! mRNA catabolic process GO:0006402 48 34 1,000 0,02236596 0,12957606 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,02236596 0,1292505 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,02236596 0,12892656 ! female gamete generation GO:0007292 43 34 1,000 0,02236596 0,12860424 ! aerobic respiration GO:0009060 47 34 1,000 0,02236596 0,12828354 ! reproductive developmental process GO:0003006 127 89 2,000 0,02286514 0,13082048 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,0236174 0,13478914 ! glycogen metabolic process GO:0005977 48 35 1,000 0,0236174 0,1344555 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,0236174 0,13412351 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,02489702 0,14104221 GO:0090047|positive regulation of transcription regulator activity, ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,02489702 0,14069567 GO:0046660|female sex differentiation, ! glucan metabolic process GO:0044042 49 36 1,000 0,02489702 0,14035082 GO:0006073|cellular glucan metabolic process, ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 0,02753901 0,15486487 ! gliogenesis GO:0042063 71 38 1,000 0,02753901 0,15448716 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,02753901 0,15411127 ! pigmentation GO:0043473 74 38 1,000 0,02753901 0,15373722 ! regulation of response to external stimulus GO:0032101 139 96 2,000 0,02780682 0,1548564 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 0,02890054 0,16055858 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,02890054 0,16017169 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,02890054 0,15978666 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 1,000 0,02890054 0,15940348 ! JNK cascade GO:0007254 54 39 1,000 0,02890054 0,15902213 ! cell growth GO:0016049 61 39 1,000 0,02890054 0,1586426 ! synapse organization GO:0050808 55 39 1,000 0,02890054 0,15826488 ! calcium ion transport GO:0006816 167 99 2,000 0,03008497 0,16435968 ! response to calcium ion GO:0051592 58 40 1,000 0,03028853 0,16507967 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,03028853 0,16468941 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,03028853 0,16430099 ! peptide metabolic process GO:0006518 56 40 1,000 0,03028853 0,1639144 ! T cell differentiation GO:0030217 65 40 1,000 0,03028853 0,16352962 ! B cell differentiation GO:0030183 62 40 1,000 0,03028853 0,16314665 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,03028853 0,16276547 ! regulation of translation GO:0006417 151 100 2,000 0,03086563 0,16548009 ! divalent metal ion transport GO:0070838 171 100 2,000 0,03086563 0,16509525 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,03170256 0,16917838 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,03170256 0,16878676 ! glucose transport GO:0015758 52 41 1,000 0,03170256 0,16839695 ! endosome transport GO:0016197 71 41 1,000 0,03170256 0,16800894 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,03170256 0,16762271 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,03170256 0,16723826 ! mitochondrial transport GO:0006839 60 42 1,000 0,03314221 0,17443269 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,03314221 0,17403444 ! cellular component disassembly GO:0022411 64 42 1,000 0,03314221 0,173638 ! hexose transport GO:0008645 54 42 1,000 0,03314221 0,17324337 GO:0015749|monosaccharide transport, ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03357859 0,17512642 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03357859 0,17473021 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03357859 0,17433578 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03357859 0,17394313 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03357859 0,17355225 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03357859 0,17316312 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03357859 0,17277573 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03357859 0,17239007 ! sleep GO:0030431 11 5 0,000 0,03357859 0,17200613 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03357859 0,17162389 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03357859 0,17124335 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03357859 0,17086449 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03357859 0,17048731 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03357859 0,17011179 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03357859 0,16973791 ! tongue development GO:0043586 6 5 0,000 0,03357859 0,16936568 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03357859 0,16899508 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03357859 0,16862609 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03357859 0,16825872 ! cobalt ion transport GO:0006824 9 5 0,000 0,03357859 0,16789294 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03357859 0,16752874 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03357859 0,16716613 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03357859 0,16680508 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03357859 0,16644558 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03357859 0,16608764 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03357859 0,16573123 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03357859 0,16537634 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03357859 0,16502297 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03357859 0,16467111 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03357859 0,16432075 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03357859 0,16397187 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03357859 0,16362447 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03357859 0,16327854 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03357859 0,16293407 ! malate metabolic process GO:0006108 7 5 0,000 0,03357859 0,16259106 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03357859 0,16224948 ! behavioral response to pain GO:0048266 7 5 0,000 0,03357859 0,16190933 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03357859 0,16157061 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03357859 0,1612333 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03357859 0,1608974 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03357859 0,16056289 ! mating behavior GO:0007617 6 5 0,000 0,03357859 0,16022977 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03357859 0,15989804 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03357859 0,15956767 ! rhythmic behavior GO:0007622 12 5 0,000 0,03357859 0,15923866 ! copulation GO:0007620 7 5 0,000 0,03357859 0,15891101 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03357859 0,1585847 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03357859 0,15825974 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03357859 0,1579361 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03357859 0,15761378 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03357859 0,15729277 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03357859 0,15697307 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03357859 0,15665467 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03357859 0,15633755 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03357859 0,15602172 ! response to protozoan GO:0001562 9 5 0,000 0,03357859 0,15570716 ! lymph vessel development GO:0001945 7 5 0,000 0,03357859 0,15539387 ! endochondral ossification GO:0001958 12 5 0,000 0,03357859 0,15508183 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03357859 0,15477104 ! parathyroid gland development GO:0060017 8 5 0,000 0,03357859 0,1544615 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03357859 0,1541532 ! anagen GO:0042640 6 5 0,000 0,03357859 0,15384612 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03357859 0,15354026 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03357859 0,15323562 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03357859 0,15293218 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03357859 0,15262994 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03357859 0,1523289 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03357859 0,15202904 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03357859 0,15173036 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03357859 0,15143285 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03357859 0,1511365 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03357859 0,15084131 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03357859 0,15054727 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03357859 0,15025438 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03357859 0,14996262 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03357859 0,149672 ! ovulation GO:0030728 6 5 0,000 0,03357859 0,1493825 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03357859 0,14909411 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,03357859 0,14880684 ! response to pH GO:0009268 9 5 0,000 0,03357859 0,14852068 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03357859 0,14823561 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03357859 0,14795163 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03357859 0,14766874 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03357859 0,14738693 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03357859 0,14710619 ! polyol catabolic process GO:0046174 7 5 0,000 0,03357859 0,14682652 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03357859 0,14654792 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03357859 0,14627036 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03357859 0,14599386 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03357859 0,1457184 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03357859 0,14544398 ! urea metabolic process GO:0019627 6 5 0,000 0,03357859 0,14517059 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03357859 0,14489822 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03357859 0,14462687 ! neutrophil activation GO:0042119 5 5 0,000 0,03357859 0,14435654 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03357859 0,14408722 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03357859 0,1438189 ! response to food GO:0032094 5 5 0,000 0,03357859 0,14355158 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03357859 0,14328525 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03357859 0,14301991 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03357859 0,14275555 ! forebrain neuron development GO:0021884 7 5 0,000 0,03357859 0,14249216 ! melanosome organization GO:0032438 7 5 0,000 0,03357859 0,14222974 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03357859 0,14196829 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03357859 0,1417078 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03357859 0,14144826 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,03357859 0,14118967 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03357859 0,14093203 ! nucleoside transport GO:0015858 6 5 0,000 0,03357859 0,14067532 ! nucleoside salvage GO:0043174 7 5 0,000 0,03357859 0,14041955 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03357859 0,1401647 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03357859 0,13991078 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03357859 0,13965778 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03357859 0,13940569 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03357859 0,13915451 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03357859 0,13890423 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03357859 0,13865485 ! depyrimidination GO:0045008 8 5 0,000 0,03357859 0,13840636 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03357859 0,13815877 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03357859 0,13791206 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03357859 0,13766622 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03357859 0,13742127 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03357859 0,13717718 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03357859 0,13693396 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,03357859 0,1366916 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03357859 0,13645009 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03357859 0,13620944 ! monocyte differentiation GO:0030224 8 5 0,000 0,03357859 0,13596963 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03357859 0,13573067 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03357859 0,13549255 ! centrosome duplication GO:0051298 5 5 0,000 0,03357859 0,13525526 ! response to UV-C GO:0010225 6 5 0,000 0,03357859 0,1350188 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03357859 0,13478316 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03357859 0,13454835 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03357859 0,13431435 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03357859 0,13408117 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03357859 0,13384879 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03357859 0,13361722 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03357859 0,13338644 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03357859 0,13315647 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03357859 0,13292728 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03357859 0,13269889 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03357859 0,13247127 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03357859 0,13224444 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03357859 0,13201838 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03357859 0,13179309 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03357859 0,13156857 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03357859 0,13134482 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03357859 0,13112182 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03357859 0,13089958 ! neural tube patterning GO:0021532 6 5 0,000 0,03357859 0,13067809 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03357859 0,13045735 ! histone demethylation GO:0016577 9 5 0,000 0,03357859 0,13023735 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03357859 0,1300181 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03357859 0,12979958 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03357859 0,1295818 ! enteric nervous system development GO:0048484 8 5 0,000 0,03357859 0,12936474 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03357859 0,12914841 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03357859 0,12893281 ! transcription termination GO:0006353 8 5 0,000 0,03357859 0,12871792 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03357859 0,12850375 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03357859 0,12829028 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03357859 0,12807753 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03357859 0,12786548 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03357859 0,12765413 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03357859 0,12744348 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03357859 0,12723353 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03357859 0,12702426 ! apical protein localization GO:0045176 6 5 0,000 0,03357859 0,12681568 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03357859 0,12660779 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03357859 0,12640057 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03357859 0,12619404 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03357859 0,12598817 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03357859 0,12578298 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03357859 0,12557846 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03357859 0,1253746 ! glial cell migration GO:0008347 10 5 0,000 0,03357859 0,1251714 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,03357859 0,12496885 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03357859 0,12476696 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03357859 0,12456573 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03357859 0,12436514 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03357859 0,12416519 ! neural plate development GO:0001840 6 5 0,000 0,03357859 0,12396589 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03357859 0,12376723 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03357859 0,1235692 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03357859 0,12337181 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03357859 0,12317504 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,03357859 0,1229789 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03357859 0,12278339 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03357859 0,12258849 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03357859 0,12239422 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03357859 0,12220056 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03357859 0,12200751 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03357859 0,12181507 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03357859 0,12162323 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03357859 0,121432 ! organ regeneration GO:0031100 7 5 0,000 0,03357859 0,12124137 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03357859 0,12105133 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03357859 0,1208619 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03357859 0,12067305 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03357859 0,12048479 GO:0055081|anion homeostasis, ! positive regulation of binding GO:0051099 59 43 1,000 0,03460708 0,12398177 ! glycolysis GO:0006096 53 44 1,000 0,03609677 0,12911754 ! cellular amino acid biosynthetic process GO:0008652 51 44 1,000 0,03609677 0,12891705 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,03609677 0,12871718 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,03609677 0,12851793 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,03609677 0,12831929 ! RNA catabolic process GO:0006401 64 45 1,000 0,03761088 0,13349541 ! regulation of translational initiation GO:0006446 64 45 1,000 0,03761088 0,13328971 ! cell maturation GO:0048469 60 45 1,000 0,03761088 0,13308465 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,03914901 0,13831446 ! histone modification GO:0016570 68 46 1,000 0,03914901 0,13810233 ! tRNA transcription GO:0009304 11 6 0,000 0,0401589 0,14144789 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,0401589 0,14123161 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,0401589 0,14101599 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,0401589 0,14080103 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0401589 0,14058672 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,0401589 0,14037306 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,0401589 0,14016005 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,0401589 0,13994769 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,0401589 0,13973597 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,0401589 0,13952488 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,0401589 0,13931444 ! prostate gland development GO:0030850 9 6 0,000 0,0401589 0,13910463 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,0401589 0,13889545 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,0401589 0,1386869 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,0401589 0,13847897 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,0401589 0,13827167 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,0401589 0,13806498 GO:0046463|acylglycerol biosynthetic process, ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,0401589 0,13785892 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,0401589 0,13765346 ! neuron adhesion GO:0007158 9 6 0,000 0,0401589 0,13744862 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,0401589 0,13724439 ! signal peptide processing GO:0006465 8 6 0,000 0,0401589 0,13704076 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,0401589 0,13683774 ! mRNA stabilization GO:0048255 15 6 0,000 0,0401589 0,13663532 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,0401589 0,13643349 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,0401589 0,13623226 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,0401589 0,13603163 ! opsonization GO:0008228 8 6 0,000 0,0401589 0,13583158 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,0401589 0,13563212 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,0401589 0,13543325 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,0401589 0,13523495 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,0401589 0,13503724 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,0401589 0,13484011 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0401589 0,13464355 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,0401589 0,13444756 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,0401589 0,13425214 ! mechanosensory behavior GO:0007638 8 6 0,000 0,0401589 0,13405729 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,0401589 0,13386301 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,0401589 0,13366928 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,0401589 0,13347612 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0401589 0,13328351 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,0401589 0,13309146 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,0401589 0,13289996 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,0401589 0,13270901 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,0401589 0,13251861 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,0401589 0,13232876 ! thymic T cell selection GO:0045061 12 6 0,000 0,0401589 0,13213945 ! protein lipoylation GO:0009249 10 6 0,000 0,0401589 0,13195068 ! pigment granule organization GO:0048753 11 6 0,000 0,0401589 0,13176244 ! drug transport GO:0015893 6 6 0,000 0,0401589 0,13157475 ! cysteine metabolic process GO:0006534 7 6 0,000 0,0401589 0,13138759 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,0401589 0,13120096 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0401589 0,13101486 ! histidine metabolic process GO:0006547 6 6 0,000 0,0401589 0,13082928 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,0401589 0,13064423 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,0401589 0,13045971 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,0401589 0,1302757 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,0401589 0,13009222 ! adenohypophysis development GO:0021984 10 6 0,000 0,0401589 0,12990925 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,0401589 0,12972679 ! hyperosmotic response GO:0006972 8 6 0,000 0,0401589 0,12954484 ! microtubule nucleation GO:0007020 10 6 0,000 0,0401589 0,12936341 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,0401589 0,12918248 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,0401589 0,12900206 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,0401589 0,12882214 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,0401589 0,12864272 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,0401589 0,1284638 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,0401589 0,12828538 ! response to dietary excess GO:0002021 7 6 0,000 0,0401589 0,12810745 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,0401589 0,12793002 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,0401589 0,12775308 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,0401589 0,12757662 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,0401589 0,12740065 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,0401589 0,12722517 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,0401589 0,12705017 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0401589 0,12687565 ! neuron apoptosis GO:0051402 8 6 0,000 0,0401589 0,12670161 ! organic alcohol transport GO:0015850 9 6 0,000 0,0401589 0,12652805 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,0401589 0,12635496 ! T cell mediated immunity GO:0002456 12 6 0,000 0,0401589 0,12618234 ! carnitine transport GO:0015879 8 6 0,000 0,0401589 0,1260102 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,0401589 0,12583852 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,0401589 0,12566731 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0401589 0,12549657 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,0401589 0,12532629 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,0401589 0,12515647 ! parturition GO:0007567 12 6 0,000 0,0401589 0,12498711 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,0401589 0,12481821 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,0401589 0,12464976 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,0401589 0,12448177 ! spindle checkpoint GO:0031577 14 6 0,000 0,0401589 0,12431423 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,0401589 0,12414714 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,0401589 0,1239805 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,0401589 0,12381431 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,0401589 0,12364856 ! macrophage differentiation GO:0030225 10 6 0,000 0,0401589 0,12348325 ! astrocyte development GO:0014002 14 6 0,000 0,0401589 0,12331839 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,0401589 0,12315396 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,0401589 0,12298998 ! interaction with symbiont GO:0051702 8 6 0,000 0,0401589 0,12282643 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,0401589 0,12266331 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0401589 0,12250063 ! eating behavior GO:0042755 6 6 0,000 0,0401589 0,12233838 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,0401589 0,12217655 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,0401589 0,12201516 ! response to copper ion GO:0046688 9 6 0,000 0,0401589 0,12185419 ! DNA topological change GO:0006265 8 6 0,000 0,0401589 0,12169364 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,0401589 0,12153352 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,0401589 0,12137382 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,0401589 0,12121453 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0401589 0,12105567 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0401589 0,12089722 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,0401589 0,12073918 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,0401589 0,12058156 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,0401589 0,12042435 ! gas homeostasis GO:0033483 11 6 0,000 0,0401589 0,12026754 ! hair follicle maturation GO:0048820 7 6 0,000 0,0401589 0,12011115 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,0401589 0,11995516 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,0401589 0,11979958 ! Schwann cell development GO:0014044 14 6 0,000 0,0401589 0,1196444 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,0401589 0,11948962 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0401589 0,11933524 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,0401589 0,11918126 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,0401589 0,11902767 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,0401589 0,11887448 ! histone ubiquitination GO:0016574 7 6 0,000 0,0401589 0,11872169 ! regulation of meiosis GO:0040020 10 6 0,000 0,0401589 0,11856929 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,0401589 0,11841727 GO:0000085|G2 phase of mitotic cell cycle, ! regulation of cell division GO:0051302 8 6 0,000 0,0401589 0,11826565 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,0401589 0,11811442 ! membrane to membrane docking GO:0022614 12 6 0,000 0,0401589 0,11796357 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,0401589 0,1178131 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,0401589 0,11766302 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,0401589 0,11751333 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,0401589 0,11736401 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,0401589 0,11721507 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0401589 0,11706651 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,0401589 0,11691832 ! protein deubiquitination GO:0016579 8 6 0,000 0,0401589 0,11677051 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,0401589 0,11662307 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,0401589 0,11647601 ! axonal fasciculation GO:0007413 9 6 0,000 0,0401589 0,11632931 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,0401589 0,11618299 ! thiamin metabolic process GO:0006772 6 6 0,000 0,0401589 0,11603703 ! midbrain development GO:0030901 6 6 0,000 0,0401589 0,11589143 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,0401589 0,11574621 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0401589 0,11560134 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,0401589 0,11545684 ! progesterone metabolic process GO:0042448 8 6 0,000 0,0401589 0,1153127 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,0401589 0,11516892 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,0401589 0,1150255 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,0401589 0,11488243 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,0401589 0,11473972 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,0401589 0,11459736 ! adult feeding behavior GO:0008343 6 6 0,000 0,0401589 0,11445536 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,0401589 0,1143137 ! blastocyst growth GO:0001832 15 6 0,000 0,0401589 0,1141724 ! pigment granule transport GO:0051904 12 6 0,000 0,0401589 0,11403145 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,0401589 0,11389084 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,0401589 0,11375058 ! catecholamine transport GO:0051937 7 6 0,000 0,0401589 0,11361067 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0401589 0,1134711 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,0401589 0,11333187 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,0401589 0,11319298 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,0401589 0,11305444 ! protein prenylation GO:0018342 10 6 0,000 0,0401589 0,11291623 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0401589 0,11277836 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,0401589 0,11264082 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,0401589 0,11250362 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,0401589 0,11236676 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,0401589 0,11223022 ! covalent chromatin modification GO:0016569 75 47 1,000 0,04071076 0,11363442 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,04071076 0,11349668 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,04071076 0,11335927 ! response to temperature stimulus GO:0009266 62 48 1,000 0,04229576 0,1176303 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,04229576 0,11748824 ! heart morphogenesis GO:0003007 65 48 1,000 0,04229576 0,11734651 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,04229576 0,11720513 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,04390363 0,12151425 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,04390363 0,12136819 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,04553397 0,12572404 ! membrane fusion GO:0006944 80 50 1,000 0,04553397 0,12557329 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,04553397 0,1254229 ! lipid modification GO:0030258 73 50 1,000 0,04553397 0,12527288 ! positive regulation of growth GO:0045927 67 50 1,000 0,04553397 0,12512321 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,04669478 0,12815991 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,04669478 0,12800716 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,04669478 0,12785477 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04669478 0,12770274 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,04669478 0,12755107 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04669478 0,12739977 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,04669478 0,12724882 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,04669478 0,12709823 ! reproductive behavior GO:0019098 12 7 0,000 0,04669478 0,126948 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,04669478 0,12679812 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,04669478 0,12664859 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,04669478 0,12649942 ! oligopeptide transport GO:0006857 11 7 0,000 0,04669478 0,12635059 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,04669478 0,12620212 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,04669478 0,126054 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,04669478 0,12590622 ! RNA methylation GO:0001510 11 7 0,000 0,04669478 0,12575879 ! pericardium development GO:0060039 8 7 0,000 0,04669478 0,1256117 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,04669478 0,12546496 ! fibril organization GO:0043206 13 7 0,000 0,04669478 0,12531856 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,04669478 0,1251725 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04669478 0,12502678 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,04669478 0,1248814 ! lipoprotein transport GO:0042953 9 7 0,000 0,04669478 0,12473636 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,04669478 0,12459165 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04669478 0,12444728 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04669478 0,12430325 ! estrogen metabolic process GO:0008210 14 7 0,000 0,04669478 0,12415954 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,04669478 0,12401617 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,04669478 0,12387313 ! chemosensory behavior GO:0007635 9 7 0,000 0,04669478 0,12373042 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,04669478 0,12358804 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,04669478 0,12344598 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,04669478 0,12330425 ! leukocyte degranulation GO:0043299 10 7 0,000 0,04669478 0,12316285 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,04669478 0,12302177 ! reflex GO:0060004 12 7 0,000 0,04669478 0,12288101 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04669478 0,12274058 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,04669478 0,12260046 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04669478 0,12246067 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,04669478 0,12232119 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,04669478 0,12218203 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04669478 0,12204319 ! spinal cord patterning GO:0021511 7 7 0,000 0,04669478 0,12190466 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,04669478 0,12176644 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,04669478 0,12162854 ! adrenal gland development GO:0030325 17 7 0,000 0,04669478 0,12149096 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,04669478 0,12135368 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,04669478 0,12121671 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,04669478 0,12108005 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,04669478 0,1209437 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,04669478 0,12080765 ! endosome organization GO:0007032 10 7 0,000 0,04669478 0,12067191 ! thyroid hormone generation GO:0006590 11 7 0,000 0,04669478 0,12053648 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,04669478 0,12040135 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,04669478 0,12026652 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,04669478 0,120132 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04669478 0,11999777 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04669478 0,11986384 ! galactose metabolic process GO:0006012 10 7 0,000 0,04669478 0,11973022 ! vesicle fusion GO:0006906 15 7 0,000 0,04669478 0,11959689 ! intracellular pH reduction GO:0051452 10 7 0,000 0,04669478 0,11946385 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,04669478 0,11933112 ! organ growth GO:0035265 11 7 0,000 0,04669478 0,11919867 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,04669478 0,11906652 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,04669478 0,11893467 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,04669478 0,1188031 ! retinol metabolic process GO:0042572 9 7 0,000 0,04669478 0,11867183 ! behavioral fear response GO:0001662 13 7 0,000 0,04669478 0,11854084 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,04669478 0,11841015 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,04669478 0,11827974 ! rRNA modification GO:0000154 12 7 0,000 0,04669478 0,11814962 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04669478 0,11801978 ! response to UV-B GO:0010224 11 7 0,000 0,04669478 0,11789024 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,04669478 0,11776097 ! intermediate filament organization GO:0045109 11 7 0,000 0,04669478 0,11763199 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,04669478 0,11750329 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,04669478 0,11737487 ! fibrinolysis GO:0042730 9 7 0,000 0,04669478 0,11724673 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,04669478 0,11711887 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,04669478 0,11699129 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,04669478 0,11686399 ! response to tropane GO:0014073 13 7 0,000 0,04669478 0,11673696 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,04669478 0,11661021 ! melanosome localization GO:0032400 10 7 0,000 0,04669478 0,11648374 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,04669478 0,11635753 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,04669478 0,11623161 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,04669478 0,11610595 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,04669478 0,11598057 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,04669478 0,11585545 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,04669478 0,11573061 ! mast cell activation GO:0045576 9 7 0,000 0,04669478 0,11560603 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,04669478 0,11548173 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,04669478 0,11535768 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,04669478 0,11523391 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,04669478 0,1151104 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,04669478 0,11498716 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,04669478 0,11486418 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,04669478 0,11474146 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,04669478 0,114619 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,04669478 0,11449681 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,04669478 0,11437487 ! regulation of lipid transport GO:0032368 13 7 0,000 0,04669478 0,1142532 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,04669478 0,11413178 ! neuroblast proliferation GO:0007405 13 7 0,000 0,04669478 0,11401062 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,04669478 0,11388972 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,04669478 0,11376907 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,04669478 0,11364868 ! diuresis GO:0030146 12 7 0,000 0,04669478 0,11352855 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,04669478 0,11340866 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,04669478 0,11328903 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04669478 0,11316966 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,04669478 0,11305053 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04669478 0,11293166 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04669478 0,11281303 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04669478 0,11269465 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,04669478 0,11257652 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,04669478 0,11245864 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,04669478 0,11234101 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,04669478 0,11222362 ! lymph node development GO:0048535 9 7 0,000 0,04669478 0,11210648 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,04669478 0,11198958 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,04669478 0,11187292 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04669478 0,11175651 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,04669478 0,11164034 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,04669478 0,11152441 ! ATP catabolic process GO:0006200 10 7 0,000 0,04669478 0,11140872 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,04669478 0,11129327 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,04669478 0,11117806 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,04669478 0,11106309 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,04669478 0,11094835 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,04669478 0,11083385 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,04669478 0,11071959 ! muscle adaptation GO:0043500 12 7 0,000 0,04669478 0,11060557 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,04669478 0,11049177 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,04669478 0,11037822 ! retina homeostasis GO:0001895 9 7 0,000 0,04669478 0,11026489 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,04669478 0,1101518 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,04669478 0,11003894 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,04669478 0,10992631 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,04669478 0,10981391 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,04669478 0,10970174 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,04669478 0,1095898 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04669478 0,10947809 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,04718642 0,11051808 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,04718642 0,11040565 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,04718642 0,11029345 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,04718642 0,11018148 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,0488606 0,11397503 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,0488606 0,11385955 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,05055615 0,11769145 ! single fertilization GO:0007338 59 53 1,000 0,05055615 0,11757245 ! glucose catabolic process GO:0006007 66 54 1,000 0,05227271 0,12144165 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,05227271 0,1213191 ! DNA catabolic process GO:0006308 67 54 1,000 0,05227271 0,12119681 ! detection of external stimulus GO:0009581 66 54 1,000 0,05227271 0,12107476 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,05227271 0,12095295 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05318653 0,12294375 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05318653 0,12282031 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05318653 0,12269712 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05318653 0,12257418 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05318653 0,12245148 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05318653 0,12232903 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05318653 0,12220682 ! phosphate transport GO:0006817 10 8 0,000 0,05318653 0,12208486 ! N-glycan processing GO:0006491 12 8 0,000 0,05318653 0,12196314 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,05318653 0,12184166 ! UTP metabolic process GO:0046051 8 8 0,000 0,05318653 0,12172043 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05318653 0,12159943 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05318653 0,12147868 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05318653 0,12135816 ! succinate metabolic process GO:0006105 14 8 0,000 0,05318653 0,12123789 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05318653 0,12111785 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05318653 0,12099805 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,05318653 0,12087849 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05318653 0,12075916 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,05318653 0,12064007 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05318653 0,12052121 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05318653 0,12040259 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,05318653 0,1202842 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05318653 0,12016604 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,05318653 0,12004811 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05318653 0,11993042 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,05318653 0,11981296 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05318653 0,11969572 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05318653 0,11957872 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05318653 0,11946194 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,05318653 0,11934539 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05318653 0,11922907 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05318653 0,11911298 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,05318653 0,11899711 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05318653 0,11888147 ! melanin metabolic process GO:0006582 12 8 0,000 0,05318653 0,11876605 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05318653 0,11865085 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05318653 0,11853588 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,05318653 0,11842113 ! macrophage activation GO:0042116 12 8 0,000 0,05318653 0,1183066 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05318653 0,1181923 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05318653 0,11807821 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,05318653 0,11796435 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,05318653 0,1178507 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05318653 0,11773727 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,05318653 0,11762407 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05318653 0,11751107 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05318653 0,1173983 ! ruffle organization GO:0031529 11 8 0,000 0,05318653 0,11728574 ! osteoblast development GO:0002076 13 8 0,000 0,05318653 0,1171734 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05318653 0,11706127 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,05318653 0,11694936 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05318653 0,11683766 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,05318653 0,11672617 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,05318653 0,1166149 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,05318653 0,11650384 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05318653 0,11639299 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05318653 0,11628235 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05318653 0,11617192 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,05318653 0,1160617 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,05318653 0,11595169 ! segment specification GO:0007379 10 8 0,000 0,05318653 0,11584188 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,05318653 0,11573229 ! cellular extravasation GO:0045123 11 8 0,000 0,05318653 0,1156229 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05318653 0,11551372 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05318653 0,11540474 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05318653 0,11529597 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05318653 0,11518741 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,05318653 0,11507905 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,05318653 0,11497089 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,05318653 0,11486294 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,05318653 0,11475519 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05318653 0,11464764 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05318653 0,11454029 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,05318653 0,11443314 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05318653 0,11432619 ! icosanoid secretion GO:0032309 12 8 0,000 0,05318653 0,11421945 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,05318653 0,1141129 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05318653 0,11400655 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05318653 0,1139004 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05318653 0,11379444 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05318653 0,11368869 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05318653 0,11358313 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05318653 0,11347776 ! sterol catabolic process GO:0016127 9 8 0,000 0,05318653 0,11337259 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05318653 0,11326762 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05318653 0,11316284 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,05318653 0,11305825 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05318653 0,11295386 ! S phase GO:0051320 8 8 0,000 0,05318653 0,11284966 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,05318653 0,11274565 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,05318653 0,11264183 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05318653 0,1125382 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05318653 0,11243477 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05318653 0,11233152 ! hormone catabolic process GO:0042447 13 8 0,000 0,05318653 0,11222847 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05318653 0,1121256 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,05318653 0,11202292 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05318653 0,11192043 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05318653 0,11181812 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05318653 0,11171601 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05318653 0,11161408 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05318653 0,11151233 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05318653 0,11141077 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05318653 0,1113094 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05318653 0,11120821 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05318653 0,1111072 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05318653 0,11100638 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,05318653 0,11090574 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,05318653 0,11080528 ! exocytosis GO:0006887 74 55 1,000 0,05400991 0,11241883 ! mesoderm development GO:0007498 76 55 1,000 0,05400991 0,11231718 ! carbohydrate transport GO:0008643 74 57 1,000 0,05754485 0,11956021 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,05754485 0,1194523 GO:0048609|reproductive process in a multicellular organism, ! developmental maturation GO:0021700 75 57 1,000 0,05754485 0,11934459 ! gonad development GO:0008406 79 57 1,000 0,05754485 0,11923707 ! viral reproductive process GO:0022415 87 58 1,000 0,05934188 0,12284997 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,05934188 0,12273949 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,05963445 0,1232338 ! telencephalon cell migration GO:0022029 16 9 0,000 0,05963445 0,12312318 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,05963445 0,12301276 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,05963445 0,12290253 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,05963445 0,1227925 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,05963445 0,12268267 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05963445 0,12257303 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,05963445 0,12246359 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,05963445 0,12235435 ! GTP metabolic process GO:0046039 9 9 0,000 0,05963445 0,1222453 ! elastic fiber assembly GO:0048251 13 9 0,000 0,05963445 0,12213644 ! social behavior GO:0035176 14 9 0,000 0,05963445 0,12202778 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,05963445 0,12191931 ! artery development GO:0060840 19 9 0,000 0,05963445 0,12181103 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,05963445 0,12170295 ! response to pain GO:0048265 16 9 0,000 0,05963445 0,12159506 ! protein complex disassembly GO:0043241 17 9 0,000 0,05963445 0,12148736 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,05963445 0,12137984 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,05963445 0,12127252 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,05963445 0,12116539 ! lung alveolus development GO:0048286 17 9 0,000 0,05963445 0,12105845 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,05963445 0,1209517 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,05963445 0,12084513 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,05963445 0,12073875 ! ventral spinal cord development GO:0021517 11 9 0,000 0,05963445 0,12063256 ! protein targeting to ER GO:0045047 19 9 0,000 0,05963445 0,12052656 ! T cell selection GO:0045058 18 9 0,000 0,05963445 0,12042074 ! endoderm development GO:0007492 12 9 0,000 0,05963445 0,12031511 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,05963445 0,12020966 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,05963445 0,1201044 ! arginine catabolic process GO:0006527 10 9 0,000 0,05963445 0,11999932 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,05963445 0,11989443 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,05963445 0,11978972 GO:0010833|telomere maintenance via telomere lengthening, ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05963445 0,11968519 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,05963445 0,11958084 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,05963445 0,11947668 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,05963445 0,11937269 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,05963445 0,11926889 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05963445 0,11916527 ! mannose metabolic process GO:0006013 9 9 0,000 0,05963445 0,11906183 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,05963445 0,11895856 ! receptor clustering GO:0043113 15 9 0,000 0,05963445 0,11885548 ! epithelial cell development GO:0002064 10 9 0,000 0,05963445 0,11875257 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,05963445 0,11864985 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,05963445 0,1185473 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,05963445 0,11844493 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,05963445 0,11834273 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,05963445 0,11824071 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,05963445 0,11813887 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,05963445 0,1180372 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,05963445 0,1179357 ! blastoderm segmentation GO:0007350 11 9 0,000 0,05963445 0,11783438 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,05963445 0,11773324 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,05963445 0,11763227 ! response to amine stimulus GO:0014075 13 9 0,000 0,05963445 0,11753147 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,05963445 0,11743084 ! erythrocyte development GO:0048821 11 9 0,000 0,05963445 0,11733039 ! renal water homeostasis GO:0003091 14 9 0,000 0,05963445 0,11723011 ! postreplication repair GO:0006301 11 9 0,000 0,05963445 0,11712999 ! mRNA cleavage GO:0006379 13 9 0,000 0,05963445 0,11703005 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,05963445 0,11693028 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,05963445 0,11683068 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,05963445 0,11673125 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,05963445 0,11663199 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,05963445 0,1165329 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,05963445 0,11643398 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,05963445 0,11633522 ! acid secretion GO:0046717 14 9 0,000 0,05963445 0,11623663 ! musculoskeletal movement GO:0050881 11 9 0,000 0,05963445 0,11613821 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,05963445 0,11603995 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,05963445 0,11594186 ! purine base metabolic process GO:0006144 18 9 0,000 0,05963445 0,11584394 ! oocyte differentiation GO:0009994 12 9 0,000 0,05963445 0,11574618 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,05963445 0,11564859 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,05963445 0,11555116 ! spleen development GO:0048536 15 9 0,000 0,05963445 0,11545389 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,05963445 0,11535679 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,05963445 0,11525985 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,05963445 0,11516308 ! detection of calcium ion GO:0005513 13 9 0,000 0,05963445 0,11506646 ! blastocyst formation GO:0001825 12 9 0,000 0,05963445 0,11497001 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,05963445 0,11487372 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,05963445 0,11477759 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,05963445 0,11468163 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,05963445 0,11458582 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05963445 0,11449017 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,05963445 0,11439468 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,05963445 0,11429935 ! prepulse inhibition GO:0060134 14 9 0,000 0,05963445 0,11420418 ! embryonic placenta development GO:0001892 12 9 0,000 0,05963445 0,11410917 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,05963445 0,11401432 ! insulin secretion GO:0030073 17 9 0,000 0,05963445 0,11391962 ! sequestering of metal ion GO:0051238 11 9 0,000 0,05963445 0,11382508 ! response to nicotine GO:0035094 16 9 0,000 0,05963445 0,1137307 ! establishment of cell polarity GO:0030010 12 9 0,000 0,05963445 0,11363647 ! nucleus localization GO:0051647 15 9 0,000 0,05963445 0,1135424 ! regulation of synapse organization GO:0050807 12 9 0,000 0,05963445 0,11344849 ! activation of MAPK activity GO:0000187 84 59 1,000 0,06115815 0,11625103 ! actin filament organization GO:0007015 95 59 1,000 0,06115815 0,11615504 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,06299334 0,11954181 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,06299334 0,11944326 GO:0035113|embryonic appendage morphogenesis, ! fertilization GO:0009566 68 60 1,000 0,06299334 0,11934487 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,06299334 0,11924665 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,06484709 0,12265486 ! fatty acid biosynthetic process GO:0006633 92 61 1,000 0,06484709 0,12255408 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,06484709 0,12245346 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,06603881 0,12460153 ! neuron fate specification GO:0048665 11 10 0,000 0,06603881 0,1244994 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,06603881 0,12439743 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,06603881 0,12429564 ! thyroid gland development GO:0030878 19 10 0,000 0,06603881 0,124194 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,06603881 0,12409254 ! synapsis GO:0007129 13 10 0,000 0,06603881 0,12399124 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,06603881 0,1238901 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,06603881 0,12378913 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,06603881 0,12368833 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,06603881 0,12358769 ! sulfate transport GO:0008272 12 10 0,000 0,06603881 0,12348721 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,06603881 0,12338689 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,06603881 0,12328674 ! androgen metabolic process GO:0008209 13 10 0,000 0,06603881 0,12318675 ! phospholipid efflux GO:0033700 16 10 0,000 0,06603881 0,12308693 ! hippocampus development GO:0021766 19 10 0,000 0,06603881 0,12298726 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,06603881 0,12288776 ! blood vessel remodeling GO:0001974 21 10 0,000 0,06603881 0,12278841 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,06603881 0,12268923 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,06603881 0,12259021 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,06603881 0,12249134 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,06603881 0,12239264 ! pathogenesis GO:0009405 13 10 0,000 0,06603881 0,1222941 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,06603881 0,12219571 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06603881 0,12209748 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,06603881 0,12199941 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,06603881 0,1219015 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,06603881 0,12180374 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,06603881 0,12170614 ! melanocyte differentiation GO:0030318 15 10 0,000 0,06603881 0,1216087 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,06603881 0,12151141 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,06603881 0,12141428 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06603881 0,12131731 ! B cell proliferation GO:0042100 14 10 0,000 0,06603881 0,12122048 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,06603881 0,12112382 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,06603881 0,1210273 ! forebrain cell migration GO:0021885 17 10 0,000 0,06603881 0,12093095 ! lipid digestion GO:0044241 15 10 0,000 0,06603881 0,12083474 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,06603881 0,12073869 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,06603881 0,12064279 ! UV protection GO:0009650 14 10 0,000 0,06603881 0,12054704 ! entry into host cell GO:0030260 20 10 0,000 0,06603881 0,12045144 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,06603881 0,120356 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,06603881 0,1202607 ! negative regulation of ossification GO:0030279 19 10 0,000 0,06603881 0,12016556 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,06603881 0,12007057 ! regulation of bone resorption GO:0045124 24 10 0,000 0,06603881 0,11997572 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,06603881 0,11988103 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,06603881 0,11978649 ! regulation of organ growth GO:0046620 11 10 0,000 0,06603881 0,11969209 ! response to dsRNA GO:0043331 18 10 0,000 0,06603881 0,11959785 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,06603881 0,11950375 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06603881 0,1194098 ! embryonic axis specification GO:0000578 12 10 0,000 0,06603881 0,119316 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,06603881 0,11922235 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,06603881 0,11912884 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,06603881 0,11903548 ! cranial nerve development GO:0021545 12 10 0,000 0,06603881 0,11894226 ! fucose catabolic process GO:0019317 16 10 0,000 0,06603881 0,11884919 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,06603881 0,11875627 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,06603881 0,11866349 ! protein sumoylation GO:0016925 12 10 0,000 0,06603881 0,11857086 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,06603881 0,11847837 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06603881 0,11838602 ! zymogen activation GO:0031638 14 10 0,000 0,06603881 0,11829382 ! salivary gland development GO:0007431 22 10 0,000 0,06603881 0,11820176 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06603881 0,11810985 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,06603881 0,11801808 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,06603881 0,11792645 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,06603881 0,11783496 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,06603881 0,11774362 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,06603881 0,11765241 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06603881 0,11756135 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,06603881 0,11747043 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,06603881 0,11737965 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,06603881 0,11728901 ! detection of bacterium GO:0016045 10 10 0,000 0,06603881 0,11719851 ! embryonic gut development GO:0048566 11 10 0,000 0,06603881 0,11710815 ! activation of innate immune response GO:0002218 10 10 0,000 0,06603881 0,11701793 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,06603881 0,11692784 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,06603881 0,1168379 ! developmental induction GO:0031128 13 10 0,000 0,06603881 0,11674809 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,06603881 0,11665842 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,06603881 0,11656889 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,06603881 0,1164795 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,06603881 0,11639024 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,06671909 0,11749916 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,06860899 0,12073503 ! viral reproduction GO:0016032 92 63 1,000 0,06860899 0,12064272 ! regulation of lipase activity GO:0060191 109 63 1,000 0,06860899 0,12055056 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,07051648 0,12380756 ! appendage morphogenesis GO:0035107 93 64 1,000 0,07051648 0,12371312 GO:0035108|limb morphogenesis, ! hexose catabolic process GO:0019320 82 64 1,000 0,07051648 0,12361883 ! rRNA transcription GO:0009303 17 11 0,000 0,07239993 0,12682394 ! respiratory burst GO:0045730 14 11 0,000 0,07239993 0,12672742 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07239993 0,12663105 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07239993 0,12653482 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,07239993 0,12643875 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,07239993 0,12634281 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,07239993 0,12624703 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07239993 0,12615139 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07239993 0,12605589 ! mating GO:0007618 14 11 0,000 0,07239993 0,12596054 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,07239993 0,12586533 ! T cell proliferation GO:0042098 20 11 0,000 0,07239993 0,12577026 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,07239993 0,12567534 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,07239993 0,12558057 ! bone resorption GO:0045453 16 11 0,000 0,07239993 0,12548593 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07239993 0,12539144 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07239993 0,12529709 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of mRNA processing GO:0050684 18 11 0,000 0,07239993 0,12520288 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07239993 0,12510881 ! syncytium formation GO:0006949 15 11 0,000 0,07239993 0,12501489 ! plasma membrane organization GO:0007009 18 11 0,000 0,07239993 0,1249211 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,07239993 0,12482746 ! mitotic spindle organization GO:0007052 15 11 0,000 0,07239993 0,12473395 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,07239993 0,12464059 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,07239993 0,12454737 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07239993 0,12445428 ! adult heart development GO:0007512 11 11 0,000 0,07239993 0,12436134 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,07239993 0,12426853 ! temperature homeostasis GO:0001659 16 11 0,000 0,07239993 0,12417586 ! L-glutamate transport GO:0015813 16 11 0,000 0,07239993 0,12408333 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,07239993 0,12399094 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07239993 0,12389868 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07239993 0,12380656 ! stem cell development GO:0048864 29 11 0,000 0,07239993 0,12371458 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,07239993 0,12362274 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07239993 0,12353103 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,07239993 0,12343946 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07239993 0,12334802 ! vasoconstriction GO:0042310 15 11 0,000 0,07239993 0,12325672 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,07239993 0,12316555 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,07239993 0,12307452 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07239993 0,12298363 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07239993 0,12289286 ! ribosome assembly GO:0042255 13 11 0,000 0,07239993 0,12280223 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,07239993 0,12271174 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,07239993 0,12262138 ! chromatin silencing GO:0006342 19 11 0,000 0,07239993 0,12253115 ! nucleosome positioning GO:0016584 13 11 0,000 0,07239993 0,12244105 ! T cell homeostasis GO:0043029 20 11 0,000 0,07239993 0,12235109 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07239993 0,12226126 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,07239993 0,12217155 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07239993 0,12208199 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07239993 0,12199255 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,07239993 0,12190324 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,07239993 0,12181407 ! oxygen transport GO:0015671 15 11 0,000 0,07239993 0,12172502 ! male genitalia development GO:0030539 13 11 0,000 0,07239993 0,12163611 ! cholesterol efflux GO:0033344 19 11 0,000 0,07239993 0,12154732 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07239993 0,12145866 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,07239993 0,12137014 ! germ cell migration GO:0008354 18 11 0,000 0,07239993 0,12128174 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,07239993 0,12119347 ! defense response to fungus GO:0050832 12 11 0,000 0,07239993 0,12110533 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07239993 0,12101732 ! lysogeny GO:0030069 18 11 0,000 0,07239993 0,12092943 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07239993 0,12084168 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07239993 0,12075405 ! reproductive structure development GO:0048608 90 65 1,000 0,07244123 0,12073538 ! appendage development GO:0048736 94 65 1,000 0,07244123 0,12064795 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,07244123 0,12056065 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,07244123 0,12047348 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,07438292 0,12361323 ! axon guidance GO:0007411 99 66 1,000 0,07438292 0,12352398 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,07831587 0,1299614 ! rhythmic process GO:0048511 105 68 1,000 0,07831587 0,1298677 ! lactation GO:0007595 20 12 0,000 0,07871808 0,13044062 ! tRNA modification GO:0006400 14 12 0,000 0,07871808 0,13034671 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,07871808 0,13025293 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,07871808 0,13015929 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,07871808 0,13006579 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,07871808 0,12997242 ! phospholipid catabolic process GO:0009395 14 12 0,000 0,07871808 0,12987918 ! peroxisomal transport GO:0043574 21 12 0,000 0,07871808 0,12978608 ! cartilage condensation GO:0001502 18 12 0,000 0,07871808 0,12969311 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,07871808 0,12960027 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,07871808 0,12950756 ! heart looping GO:0001947 15 12 0,000 0,07871808 0,12941499 ! palate development GO:0060021 15 12 0,000 0,07871808 0,12932255 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,07871808 0,12923025 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,07871808 0,12913807 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,07871808 0,12904603 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,07871808 0,12895411 ! arginine metabolic process GO:0006525 13 12 0,000 0,07871808 0,12886233 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,07871808 0,12877068 ! methionine metabolic process GO:0006555 13 12 0,000 0,07871808 0,12867916 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,07871808 0,12858777 ! Golgi organization GO:0007030 18 12 0,000 0,07871808 0,12849651 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,07871808 0,12840537 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,07871808 0,12831437 ! monoamine transport GO:0015844 13 12 0,000 0,07871808 0,1282235 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07871808 0,12813275 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,07871808 0,12804213 ! L-amino acid transport GO:0015807 20 12 0,000 0,07871808 0,12795164 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,07871808 0,12786128 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,07871808 0,12777105 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,07871808 0,12768094 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07871808 0,12759096 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,07871808 0,12750111 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,07871808 0,12741138 ! cerebellum development GO:0021549 13 12 0,000 0,07871808 0,12732178 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,07871808 0,12723231 ! histone methylation GO:0016571 15 12 0,000 0,07871808 0,12714296 ! autonomic nervous system development GO:0048483 23 12 0,000 0,07871808 0,12705374 ! gland morphogenesis GO:0022612 23 12 0,000 0,07871808 0,12696464 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,07871808 0,12687567 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,07871808 0,12678682 ! regulation of epidermis development GO:0045682 17 12 0,000 0,07871808 0,12669809 ! intestinal absorption GO:0050892 19 12 0,000 0,07871808 0,12660949 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,07871808 0,12652102 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,07871808 0,12643266 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,07871808 0,12634444 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,07871808 0,12625633 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,07871808 0,12616835 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,07871808 0,12608048 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,07871808 0,12599275 ! microspike assembly GO:0030035 23 12 0,000 0,07871808 0,12590513 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,07871808 0,12581763 ! response to cold GO:0009409 14 12 0,000 0,07871808 0,12573026 ! response to drug GO:0042493 108 69 1,000 0,08030651 0,12817833 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,08030651 0,12808944 ! response to metal ion GO:0010038 103 70 1,000 0,08231286 0,13119859 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,08231286 0,13110773 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,0843346 0,134235 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,0843346 0,13414217 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,0843346 0,13404947 ! monosaccharide catabolic process GO:0046365 91 71 1,000 0,0843346 0,13395689 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,08499355 0,1349104 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,08499355 0,13481736 ! cGMP metabolic process GO:0046068 16 13 0,000 0,08499355 0,13472444 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,08499355 0,13463166 ! water transport GO:0006833 17 13 0,000 0,08499355 0,134539 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,08499355 0,13444647 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,08499355 0,13435407 ! lipid localization GO:0010876 24 13 0,000 0,08499355 0,13426179 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,08499355 0,13416964 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,08499355 0,13407762 ! organelle fusion GO:0048284 28 13 0,000 0,08499355 0,13398572 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,08499355 0,13389395 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,08499355 0,13380231 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,08499355 0,13371079 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,08499355 0,13361939 ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,08499355 0,13352812 ! glutamate metabolic process GO:0006536 18 13 0,000 0,08499355 0,13343698 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,08499355 0,13334595 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,08499355 0,13325506 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,08499355 0,13316428 ! NAD metabolic process GO:0019674 21 13 0,000 0,08499355 0,13307363 ! exocrine system development GO:0035272 27 13 0,000 0,08499355 0,13298311 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,08499355 0,1328927 ! bone mineralization GO:0030282 15 13 0,000 0,08499355 0,13280242 ! regulation of exocytosis GO:0017157 17 13 0,000 0,08499355 0,13271227 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,08499355 0,13262223 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,08499355 0,13253232 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,08499355 0,13244253 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,08499355 0,13235286 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,08499355 0,13226331 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,08499355 0,13217388 ! genitalia development GO:0048806 15 13 0,000 0,08499355 0,13208457 ! cellular pigmentation GO:0033059 24 13 0,000 0,08499355 0,13199539 ! tissue regeneration GO:0042246 21 13 0,000 0,08499355 0,13190632 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,08499355 0,13181738 ! cofactor transport GO:0051181 19 13 0,000 0,08499355 0,13172855 ! NADP metabolic process GO:0006739 18 13 0,000 0,08499355 0,13163984 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,08499355 0,13155126 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,08499355 0,13146279 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08499355 0,13137444 ! gas transport GO:0015669 18 13 0,000 0,08499355 0,13128621 ! regulation of RNA stability GO:0043487 28 13 0,000 0,08499355 0,1311981 ! heme biosynthetic process GO:0006783 20 13 0,000 0,08499355 0,13111011 ! regulation of axon extension GO:0030516 23 13 0,000 0,08499355 0,13102223 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,08499355 0,13093447 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,08499355 0,13084683 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,08499355 0,13075931 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,08499355 0,1306719 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,08499355 0,13058461 ! response to hypoxia GO:0001666 132 72 1,000 0,08637144 0,13261303 ! response to oxygen levels GO:0070482 137 74 1,000 0,09048927 0,13884277 ! protein import into nucleus GO:0006606 118 74 1,000 0,09048927 0,13875021 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,09048927 0,13865777 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,09122664 0,13969458 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,09122664 0,13960164 ! superoxide anion generation GO:0042554 18 14 0,000 0,09122664 0,13950882 ! neuron maturation GO:0042551 21 14 0,000 0,09122664 0,13941612 ! regulation of S phase GO:0033261 18 14 0,000 0,09122664 0,13932355 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09122664 0,1392311 ! myotube differentiation GO:0014902 21 14 0,000 0,09122664 0,13913877 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,09122664 0,13904656 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,09122664 0,13895448 ! inositol metabolic process GO:0006020 20 14 0,000 0,09122664 0,13886252 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09122664 0,13877068 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09122664 0,13867896 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09122664 0,13858736 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09122664 0,13849588 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09122664 0,13840453 ! response to cAMP GO:0051591 19 14 0,000 0,09122664 0,13831329 ! limbic system development GO:0021761 25 14 0,000 0,09122664 0,13822218 ! startle response GO:0001964 21 14 0,000 0,09122664 0,13813118 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09122664 0,13804031 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,09122664 0,13794955 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,09122664 0,13785891 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,09122664 0,13776839 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,09122664 0,137678 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,09122664 0,13758771 ! glycine metabolic process GO:0006544 22 14 0,000 0,09122664 0,13749755 ! pituitary gland development GO:0021983 23 14 0,000 0,09122664 0,13740751 ! lysosomal transport GO:0007041 20 14 0,000 0,09122664 0,13731758 ! regulation of heart rate GO:0002027 23 14 0,000 0,09122664 0,13722777 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09122664 0,13713808 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09122664 0,13704851 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,09122664 0,13695905 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,09122664 0,13686971 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,09122664 0,13678049 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,09122664 0,13669138 ! axon cargo transport GO:0008088 27 14 0,000 0,09122664 0,13660239 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09122664 0,13651351 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,09122664 0,13642475 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,09122664 0,1363361 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09122664 0,13624757 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09122664 0,13615916 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,09122664 0,13607086 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09122664 0,13598267 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,09122664 0,1358946 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09122664 0,13580664 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,09122664 0,1357188 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,09122664 0,13563107 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,09122664 0,13554345 ! muscle maintenance GO:0046716 19 14 0,000 0,09122664 0,13545595 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,09122664 0,13536856 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09122664 0,13528128 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09122664 0,13519411 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,09122664 0,13510706 ! cell killing GO:0001906 20 14 0,000 0,09122664 0,13502012 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,09122664 0,13493329 ! cilium assembly GO:0042384 20 14 0,000 0,09122664 0,13484657 ! peptide hormone secretion GO:0030072 23 14 0,000 0,09122664 0,13475996 ! response to inorganic substance GO:0010035 115 75 1,000 0,09256966 0,13665611 ! regulation of ligase activity GO:0051340 114 75 1,000 0,09256966 0,13656845 ! nuclear import GO:0051170 121 75 1,000 0,09256966 0,13648091 ! amine biosynthetic process GO:0009309 97 76 1,000 0,094664 0,1394793 ! response to unfolded protein GO:0006986 99 76 1,000 0,094664 0,13939001 ! regulation of protein transport GO:0051223 114 76 1,000 0,094664 0,13930082 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 148 77 1,000 0,09677199 0,14231175 ! sex differentiation GO:0007548 105 77 1,000 0,09677199 0,14222082 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,09741762 0,14307824 ! positive regulation of cell size GO:0045793 20 15 0,000 0,09741762 0,14298693 ! metencephalon development GO:0022037 19 15 0,000 0,09741762 0,14289574 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,09741762 0,14280466 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,09741762 0,14271371 ! skin development GO:0043588 25 15 0,000 0,09741762 0,14262286 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,09741762 0,14253214 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,09741762 0,14244152 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,09741762 0,14235103 ! bile acid metabolic process GO:0008206 22 15 0,000 0,09741762 0,14226065 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,09741762 0,14217038 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,09741762 0,14208023 ! adult walking behavior GO:0007628 25 15 0,000 0,09741762 0,14199019 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,09741762 0,14190026 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,09741762 0,14181045 ! myoblast differentiation GO:0045445 27 15 0,000 0,09741762 0,14172076 ! centrosome cycle GO:0007098 16 15 0,000 0,09741762 0,14163117 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,09741762 0,1415417 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,09741762 0,14145235 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,09741762 0,1413631 ! cerebral cortex development GO:0021987 29 15 0,000 0,09741762 0,14127397 ! response to osmotic stress GO:0006970 22 15 0,000 0,09741762 0,14118495 ! vesicle coating GO:0006901 25 15 0,000 0,09741762 0,14109604 ! DNA integration GO:0015074 22 15 0,000 0,09741762 0,14100725 ! peptide secretion GO:0002790 27 15 0,000 0,09741762 0,14091856 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,09741762 0,14082999 ! regulation of vasodilation GO:0042312 24 15 0,000 0,09741762 0,14074153 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,09741762 0,14065318 ! neuron recognition GO:0008038 22 15 0,000 0,09741762 0,14056494 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,09741762 0,14047681 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,09741762 0,1403888 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,09741762 0,14030089 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,09741762 0,14021309 ! biomineral formation GO:0031214 18 15 0,000 0,09741762 0,1401254 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,09741762 0,14003782 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,09741762 0,13995035 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,09741762 0,13986299 ! organic cation transport GO:0015695 19 15 0,000 0,09741762 0,13977574 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,09741762 0,1396886 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,09741762 0,13960157 ! defense response to virus GO:0051607 27 15 0,000 0,09741762 0,13951464 ! peptide hormone processing GO:0016486 19 15 0,000 0,09741762 0,13942783 ! cellular respiration GO:0045333 107 79 1,000 0,10102784 0,144505 ! T cell activation GO:0042110 134 79 1,000 0,10102784 0,14441519 ! alcohol catabolic process GO:0046164 104 80 1,000 0,10317515 0,14739308 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,10317515 0,14730158 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 1,000 0,10317515 0,14721021 ! forebrain development GO:0030900 131 80 1,000 0,10317515 0,14711894 ! protein secretion GO:0009306 27 16 0,000 0,10356677 0,14758586 ! hormone secretion GO:0046879 25 16 0,000 0,10356677 0,14749447 ! bone remodeling GO:0046849 24 16 0,000 0,10356677 0,1474032 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,10356677 0,14731204 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,10356677 0,147221 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,10356677 0,14713007 ! patterning of blood vessels GO:0001569 24 16 0,000 0,10356677 0,14703924 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,10356677 0,14694854 GO:0042744|hydrogen peroxide catabolic process, ! protein polyubiquitination GO:0000209 26 16 0,000 0,10356677 0,14685794 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,10356677 0,14676745 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,10356677 0,14667708 ! regulation of protein binding GO:0043393 27 16 0,000 0,10356677 0,14658682 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,10356677 0,14649666 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,10356677 0,14640662 ! protein export from nucleus GO:0006611 24 16 0,000 0,10356677 0,14631669 ! negative regulation of immune response GO:0050777 28 16 0,000 0,10356677 0,14622687 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,10356677 0,14613716 ! DNA replication initiation GO:0006270 25 16 0,000 0,10356677 0,14604756 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,10356677 0,14595807 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,10356677 0,14586869 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,10356677 0,14577942 ! diencephalon development GO:0021536 25 16 0,000 0,10356677 0,14569026 ! neural crest cell migration GO:0001755 24 16 0,000 0,10356677 0,14560121 ! G1 phase GO:0051318 27 16 0,000 0,10356677 0,14551226 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,10356677 0,14542343 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,10356677 0,1453347 ! steroid catabolic process GO:0006706 22 16 0,000 0,10356677 0,14524608 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,10356677 0,14515757 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,10356677 0,14506917 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,10356677 0,14498087 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,10356677 0,14489269 ! sperm-egg recognition GO:0035036 16 16 0,000 0,10356677 0,14480461 GO:0007339|binding of sperm to zona pellucida, ! nerve development GO:0021675 18 16 0,000 0,10356677 0,14471663 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,10356677 0,14462876 ! response to protein stimulus GO:0051789 111 81 1,000 0,10533502 0,14700883 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,10533502 0,14691968 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,10750719 0,14985851 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,10750719 0,14976774 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,10967438 0,15269436 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,10967438 0,15260199 ! negative regulation of defense response GO:0031348 19 17 0,000 0,10967438 0,15250972 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,10967438 0,15241757 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,10967438 0,15232553 ! glycerol metabolic process GO:0006071 20 17 0,000 0,10967438 0,15223361 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,10967438 0,15214179 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,10967438 0,15205008 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,10967438 0,15195848 ! signal complex assembly GO:0007172 29 17 0,000 0,10967438 0,151867 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,10967438 0,15177562 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,10967438 0,15168436 ! memory GO:0007613 25 17 0,000 0,10967438 0,1515932 ! keratinization GO:0031424 17 17 0,000 0,10967438 0,15150215 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,10967438 0,15141121 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,10967438 0,15132039 ! retinoid metabolic process GO:0001523 22 17 0,000 0,10967438 0,15122967 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,10967438 0,15113906 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,10967438 0,15104855 ! vacuolar transport GO:0007034 24 17 0,000 0,10967438 0,15095816 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,10967438 0,15086787 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,10967438 0,15077769 ! membrane budding GO:0006900 29 17 0,000 0,10967438 0,15068762 ! heme metabolic process GO:0042168 27 17 0,000 0,10967438 0,15059766 ! body fluid secretion GO:0007589 27 17 0,000 0,10967438 0,15050781 ! stem cell differentiation GO:0048863 36 17 0,000 0,10967438 0,15041806 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,10967438 0,15032842 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,10967438 0,15023888 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,10967438 0,15014945 ! sensory perception of pain GO:0019233 23 17 0,000 0,10967438 0,15006013 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,10967438 0,14997092 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,10967438 0,14988181 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,10967438 0,14979281 ! synaptogenesis GO:0007416 24 17 0,000 0,10967438 0,14970391 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,10967438 0,14961511 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,10967438 0,14952643 ! cell-cell junction organization GO:0045216 25 17 0,000 0,10967438 0,14943785 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,10967438 0,14934937 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,10967438 0,149261 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,10967438 0,14917273 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,10967438 0,14908456 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,10967438 0,14899651 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,10967438 0,14890855 ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,10969139 0,14884377 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,10969139 0,14875601 ! transcription initiation GO:0006352 118 85 1,000 0,11409483 0,15463648 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,11409483 0,15454541 ! regulation of protein localization GO:0032880 132 85 1,000 0,11409483 0,15445445 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,11574073 0,1565904 ! positive regulation of translation GO:0045727 28 18 0,000 0,11574073 0,15649834 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,11574073 0,15640639 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,11574073 0,15631455 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,11574073 0,15622282 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,11574073 0,15613119 ! cAMP metabolic process GO:0046058 33 18 0,000 0,11574073 0,15603967 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,11574073 0,15594826 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,11574073 0,15585696 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,11574073 0,15576576 ! axis specification GO:0009798 26 18 0,000 0,11574073 0,15567467 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,11574073 0,15558368 GO:0050886|endocrine process, ! pancreas development GO:0031016 26 18 0,000 0,11574073 0,1554928 ! glutamine metabolic process GO:0006541 23 18 0,000 0,11574073 0,15540203 ! response to retinoic acid GO:0032526 25 18 0,000 0,11574073 0,15531137 ! pigmentation during development GO:0048066 31 18 0,000 0,11574073 0,15522081 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,11574073 0,15513035 ! fucose metabolic process GO:0006004 26 18 0,000 0,11574073 0,15504 ! response to fungus GO:0009620 19 18 0,000 0,11574073 0,15494976 ! peptide cross-linking GO:0018149 31 18 0,000 0,11574073 0,15485962 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,11574073 0,15476958 ! heart process GO:0003015 27 18 0,000 0,11574073 0,15467965 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,11574073 0,15458983 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,11574073 0,15450011 ! visual learning GO:0008542 35 18 0,000 0,11574073 0,15441049 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,11574073 0,15432097 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,11574073 0,15423157 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,11574073 0,15414226 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,11574073 0,15405306 ! vitamin transport GO:0051180 24 18 0,000 0,11574073 0,15396396 ! hormone transport GO:0009914 27 18 0,000 0,11574073 0,15387496 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,11574073 0,15378607 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,11574073 0,15369728 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,11574073 0,15360859 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,11574073 0,15352 ! cell-cell recognition GO:0009988 20 18 0,000 0,11574073 0,15343152 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,11574073 0,15334313 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,11574073 0,15325485 ! protein processing GO:0016485 114 88 1,000 0,1207838 0,15984047 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,12176609 0,16104773 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,12176609 0,16095518 ! positive regulation of ossification GO:0045778 30 19 0,000 0,12176609 0,16086273 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,12176609 0,16077038 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,12176609 0,16067814 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,12176609 0,16058601 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,12176609 0,16049399 ! regeneration GO:0031099 32 19 0,000 0,12176609 0,16040206 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,12176609 0,16031025 ! sensory perception of taste GO:0050909 23 19 0,000 0,12176609 0,16021854 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,12176609 0,16012693 ! smooth muscle contraction GO:0006939 36 19 0,000 0,12176609 0,16003543 ! peroxisome organization GO:0007031 29 19 0,000 0,12176609 0,15994403 ! digestive system process GO:0022600 30 19 0,000 0,12176609 0,15985274 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,12176609 0,15976155 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,12176609 0,15967047 ! response to vitamin A GO:0033189 26 19 0,000 0,12176609 0,15957949 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,12176609 0,15948861 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,12176609 0,15939784 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,12176609 0,15930717 ! cytolysis GO:0019835 20 19 0,000 0,12176609 0,1592166 ! renal system process GO:0003014 35 19 0,000 0,12176609 0,15912614 ! vasodilation GO:0042311 33 19 0,000 0,12176609 0,15903578 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,12176609 0,15894552 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,12176609 0,15885536 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,12176609 0,15876531 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,12176609 0,15867536 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,12176609 0,15858551 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,12176609 0,15849576 ! sarcomere organization GO:0045214 23 19 0,000 0,12176609 0,15840611 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,12176609 0,15831657 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,12176609 0,15822712 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,12176609 0,15813778 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,12176609 0,15804854 GO:0043450|alkene biosynthetic process, ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,12176609 0,15795939 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,12176609 0,15787035 ! protein stabilization GO:0050821 26 19 0,000 0,12176609 0,15778141 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,1230348 0,15933561 ! regulation of T cell activation GO:0050863 128 89 1,000 0,1230348 0,15924594 ! leukocyte differentiation GO:0002521 143 90 1,000 0,12529607 0,16208153 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,12775073 0,16516396 ! iron ion transport GO:0006826 37 20 0,000 0,12775073 0,16507117 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,12775073 0,16497849 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,12775073 0,16488591 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,12775073 0,16479343 ! response to vitamin GO:0033273 29 20 0,000 0,12775073 0,16470106 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,12775073 0,16460879 ! spinal cord development GO:0021510 31 20 0,000 0,12775073 0,16451662 ! response to ethanol GO:0045471 37 20 0,000 0,12775073 0,16442456 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,12775073 0,1643326 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,12775073 0,16424074 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,12775073 0,16414899 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,12775073 0,16405733 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,12775073 0,16396578 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,12775073 0,16387434 ! pallium development GO:0021543 38 20 0,000 0,12775073 0,16378299 ! DNA modification GO:0006304 28 20 0,000 0,12775073 0,16369175 ! collagen fibril organization GO:0030199 45 20 0,000 0,12775073 0,1636006 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,12775073 0,16350956 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,12775073 0,16341862 ! collagen catabolic process GO:0030574 25 20 0,000 0,12775073 0,16332779 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,12775073 0,16323705 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,12775073 0,16314641 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,12775073 0,16305587 ! alditol metabolic process GO:0019400 24 20 0,000 0,12775073 0,16296544 ! actin filament-based movement GO:0030048 34 20 0,000 0,12775073 0,1628751 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,12984844 0,16545785 ! cell fate commitment GO:0045165 141 92 1,000 0,12984844 0,16536623 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,13213907 0,1681903 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,13213907 0,16809727 ! carbohydrate catabolic process GO:0016052 121 93 1,000 0,13213907 0,16800435 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,13369494 0,16988859 ! regulation of cell killing GO:0031341 34 21 0,000 0,13369494 0,16979478 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,13369494 0,16970108 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,13369494 0,16960747 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,13369494 0,16951398 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,13369494 0,16942058 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,13369494 0,16932729 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,13369494 0,1692341 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,13369494 0,16914101 ! phototransduction GO:0007602 25 21 0,000 0,13369494 0,16904802 ! visual behavior GO:0007632 39 21 0,000 0,13369494 0,16895514 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,13369494 0,16886236 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,13369494 0,16876968 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,13369494 0,1686771 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,13369494 0,16858462 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,13369494 0,16849225 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,13369494 0,16839997 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,13369494 0,1683078 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,13369494 0,16821573 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,13369494 0,16812376 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,13369494 0,16803189 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,13369494 0,16794012 ! fatty acid transport GO:0015908 30 21 0,000 0,13369494 0,16784845 ! platelet activation GO:0030168 28 21 0,000 0,13369494 0,16775687 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,13369494 0,1676654 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,13369494 0,16757403 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,13369494 0,16748276 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,13369494 0,16739159 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,13369494 0,16730052 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,13369494 0,16720954 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,13369494 0,16711867 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,13369494 0,16702789 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,13369494 0,16693722 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,13369494 0,16684664 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,13369494 0,16675616 ! angiogenesis GO:0001525 149 95 1,000 0,13674806 0,17047184 ! in utero embryonic development GO:0001701 147 96 1,000 0,13906596 0,17326745 ! protein maturation GO:0051604 129 96 1,000 0,13906596 0,17317364 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,13959897 0,1737433 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,13959897 0,17364934 ! viral genome replication GO:0019079 29 22 0,000 0,13959897 0,17355547 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,13959897 0,17346171 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,13959897 0,17336805 ! leukocyte adhesion GO:0007159 38 22 0,000 0,13959897 0,17327449 ! molting cycle process GO:0022404 40 22 0,000 0,13959897 0,17318103 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,13959897 0,17308767 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,13959897 0,17299441 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,13959897 0,17290125 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,13959897 0,17280819 ! vasculogenesis GO:0001570 33 22 0,000 0,13959897 0,17271524 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,13959897 0,17262238 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,13959897 0,17252962 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,13959897 0,17243696 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,13959897 0,1723444 ! lysosome organization GO:0007040 37 22 0,000 0,13959897 0,17225194 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,13959897 0,17215958 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,13959897 0,17206732 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,13959897 0,17197516 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,13959897 0,1718831 ! membrane depolarization GO:0051899 35 22 0,000 0,13959897 0,17179113 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,13959897 0,17169926 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,13959897 0,1716075 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,13959897 0,17151583 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,13959897 0,17142425 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,13959897 0,17133278 ! blastocyst development GO:0001824 37 22 0,000 0,13959897 0,1712414 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,13959897 0,17115012 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,1454631 0,17824461 ! neuron fate commitment GO:0048663 32 23 0,000 0,1454631 0,17814969 ! embryonic pattern specification GO:0009880 31 23 0,000 0,1454631 0,17805488 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,1454631 0,17796017 ! vesicle targeting GO:0006903 32 23 0,000 0,1454631 0,17786556 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,1454631 0,17777106 ! osteoblast differentiation GO:0001649 40 23 0,000 0,1454631 0,17767665 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,1454631 0,17758234 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,1454631 0,17748813 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,1454631 0,17739402 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,1454631 0,17730001 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,1454631 0,1772061 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,1454631 0,1771123 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,1454631 0,17701859 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,1454631 0,17692497 ! cell fate determination GO:0001709 45 23 0,000 0,1454631 0,17683146 ! pentose metabolic process GO:0019321 31 23 0,000 0,1454631 0,17673805 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,1454631 0,17664473 ! spermatid development GO:0007286 33 23 0,000 0,1454631 0,17655152 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,1454631 0,1764584 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,1454631 0,17636538 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,1454631 0,17627246 ! telomere organization GO:0032200 32 23 0,000 0,1454631 0,17617963 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,1454631 0,17608691 ! regulation of amine transport GO:0051952 38 23 0,000 0,1454631 0,17599428 ! liver development GO:0001889 40 23 0,000 0,1454631 0,17590175 ! extracellular structure organization GO:0043062 156 99 1,000 0,14607059 0,17654354 ! protein import GO:0017038 156 99 1,000 0,14607059 0,17645081 ! protein localization in organelle GO:0033365 161 100 1,000 0,14842171 0,17919681 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,1512876 0,18256111 ! initiation of viral infection GO:0019059 42 24 0,000 0,1512876 0,18246537 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,1512876 0,18236974 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,1512876 0,18227421 ! superoxide metabolic process GO:0006801 32 24 0,000 0,1512876 0,18217878 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,1512876 0,18208345 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,1512876 0,18198822 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,1512876 0,18189308 ! sperm motility GO:0030317 27 24 0,000 0,1512876 0,18179805 ! vacuole organization GO:0007033 39 24 0,000 0,1512876 0,18170312 ! neural crest cell development GO:0014032 39 24 0,000 0,1512876 0,18160828 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,1512876 0,18151355 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,1512876 0,18141891 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,1512876 0,18132437 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,1512876 0,18122993 ! glutathione metabolic process GO:0006749 29 24 0,000 0,1512876 0,18113559 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,1512876 0,18104135 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,1512876 0,1809472 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,1512876 0,18085315 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,15707272 0,18767131 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,15707272 0,18757387 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,15707272 0,18747653 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,15707272 0,18737929 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,15707272 0,18728215 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,15707272 0,18718511 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,15707272 0,18708817 ! peptide transport GO:0015833 43 25 0,000 0,15707272 0,18699134 ! male gonad development GO:0008584 33 25 0,000 0,15707272 0,1868946 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,15707272 0,18679797 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,15707272 0,18670143 ! phospholipid transport GO:0015914 35 25 0,000 0,15707272 0,18660499 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,15707272 0,18650865 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,15707272 0,18641242 ! detection of light stimulus GO:0009583 30 25 0,000 0,15707272 0,18631628 ! leukocyte proliferation GO:0070661 39 25 0,000 0,15707272 0,18622024 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,16281875 0,19293309 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,16281875 0,19283374 ! translational initiation GO:0006413 43 26 0,000 0,16281875 0,19273449 ! circadian rhythm GO:0007623 42 26 0,000 0,16281875 0,19263535 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,16281875 0,19253631 ! post-embryonic development GO:0009791 42 26 0,000 0,16281875 0,19243737 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,16281875 0,19233853 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,16281875 0,19223979 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,16281875 0,19214116 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,16281875 0,19204263 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,16281875 0,19194419 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,16281875 0,19184586 ! regulation of coagulation GO:0050818 39 26 0,000 0,16281875 0,19174763 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,16852593 0,19836727 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,16852593 0,1982658 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,16852593 0,19816444 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,16852593 0,19806318 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,16852593 0,19796202 ! acute-phase response GO:0006953 42 27 0,000 0,16852593 0,19786097 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,16852593 0,19776002 ! myofibril assembly GO:0030239 36 27 0,000 0,16852593 0,19765917 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,16852593 0,19755843 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,16852593 0,19745779 ! natural killer cell activation GO:0030101 35 27 0,000 0,16852593 0,19735725 ! lipid oxidation GO:0034440 38 27 0,000 0,16852593 0,19725681 GO:0019395|fatty acid oxidation, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,16852593 0,19715648 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,16852593 0,19705625 ! gene silencing GO:0016458 41 27 0,000 0,16852593 0,19695612 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,17419453 0,20347761 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,17419453 0,20337432 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,17419453 0,20327114 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,17419453 0,20316806 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,17419453 0,20306509 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,17419453 0,20296222 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,17419453 0,20285945 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,17419453 0,20275679 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,17419453 0,20265423 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,17419453 0,20255178 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,17419453 0,20244943 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,17419453 0,20234718 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,17419453 0,20224504 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,17419453 0,202143 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,17419453 0,20204106 ! mesoderm formation GO:0001707 46 28 0,000 0,17419453 0,20193922 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,17419453 0,20183749 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,17419453 0,20173586 ! BMP signaling pathway GO:0030509 40 28 0,000 0,17419453 0,20163433 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,17419453 0,20153291 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,17419453 0,20143158 ! placenta development GO:0001890 37 28 0,000 0,17419453 0,20133036 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,17982481 0,20773333 ! regulation of innate immune response GO:0045088 38 29 0,000 0,17982481 0,20762904 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,17982481 0,20752486 ! protein targeting to membrane GO:0006612 53 29 0,000 0,17982481 0,20742079 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,17982481 0,20731682 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,17982481 0,20721295 ! muscle cell development GO:0055001 38 29 0,000 0,17982481 0,20710919 ! formation of primary germ layer GO:0001704 48 29 0,000 0,17982481 0,20700553 ! telencephalon development GO:0021537 52 29 0,000 0,17982481 0,20690198 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,17982481 0,20679853 ! eye morphogenesis GO:0048592 51 29 0,000 0,17982481 0,20669518 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,17982481 0,20659194 ! tissue homeostasis GO:0001894 42 29 0,000 0,17982481 0,20648879 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,18541702 0,21280396 ! collagen metabolic process GO:0032963 40 30 0,000 0,18541702 0,21269783 ! organic anion transport GO:0015711 51 30 0,000 0,18541702 0,21259179 ! cholesterol transport GO:0030301 46 30 0,000 0,18541702 0,21248587 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,18541702 0,21238005 ! spliceosome assembly GO:0000245 49 30 0,000 0,18541702 0,21227434 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,18541702 0,21216873 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,18541702 0,21206322 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,18541702 0,21195782 ! ceramide metabolic process GO:0006672 43 30 0,000 0,18541702 0,21185253 ! hindbrain development GO:0030902 45 30 0,000 0,18541702 0,21174734 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,18541702 0,21164225 ! adult locomotory behavior GO:0008344 47 30 0,000 0,18541702 0,21153727 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,18541702 0,21143239 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,18541702 0,21132762 ! negative regulation of secretion GO:0051048 49 31 0,000 0,19097142 0,2175504 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,19097142 0,2174427 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,19097142 0,21733511 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,19097142 0,21722763 ! odontogenesis GO:0042476 50 31 0,000 0,19097142 0,21712025 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,19097142 0,21701297 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,19097142 0,21690581 ! metanephros development GO:0001656 58 31 0,000 0,19097142 0,21679875 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,19097142 0,21669179 ! cell fate specification GO:0001708 37 31 0,000 0,19097142 0,21658494 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,19097142 0,2164782 ! RNA modification GO:0009451 40 31 0,000 0,19097142 0,21637156 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,19648826 0,22251255 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,19648826 0,22240305 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,19648826 0,22229365 GO:0006639|acylglycerol metabolic process, ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,19648826 0,22218436 ! cytokine production GO:0001816 44 32 0,000 0,19648826 0,22207518 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,19648826 0,22196611 ! vesicle localization GO:0051648 47 32 0,000 0,19648826 0,22185714 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,20196779 0,22793225 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,20196779 0,22782046 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,20196779 0,22770879 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,20196779 0,22759722 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,20196779 0,22748576 ! actomyosin structure organization GO:0031032 43 33 0,000 0,20196779 0,22737441 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,20196779 0,22726317 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,20196779 0,22715204 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,20196779 0,22704102 ! positive regulation of cell development GO:0010720 54 33 0,000 0,20196779 0,22693011 ! lipid homeostasis GO:0055088 55 33 0,000 0,20196779 0,2268193 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,20196779 0,2267086 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,20196779 0,22659801 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,20196779 0,22648753 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,20741027 0,2324774 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,20741027 0,23236416 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,20741027 0,23225104 ! feeding behavior GO:0007631 45 34 0,000 0,20741027 0,23213802 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,20741027 0,23202511 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,20741027 0,23191231 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,20741027 0,23179963 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,20741027 0,23168705 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,20741027 0,23157458 ! polyol metabolic process GO:0019751 44 34 0,000 0,20741027 0,23146222 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,20741027 0,23134997 ! embryonic organ development GO:0048568 45 34 0,000 0,20741027 0,23123782 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,20741027 0,23112579 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,21281595 0,23703471 ! Notch signaling pathway GO:0007219 56 35 0,000 0,21281595 0,23691998 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,21281595 0,23680536 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,21281595 0,23669085 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,21281595 0,23657645 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,21281595 0,23646216 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,21281595 0,23634798 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,21281595 0,23623392 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,21281595 0,23611996 ! pigment metabolic process GO:0042440 61 35 0,000 0,21281595 0,23600611 ! protein homooligomerization GO:0051260 52 35 0,000 0,21281595 0,23589237 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,21818506 0,24172718 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,21818506 0,2416108 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,21818506 0,24149453 ! organic ether metabolic process GO:0018904 46 36 0,000 0,21818506 0,24137837 ! tissue remodeling GO:0048771 62 36 0,000 0,21818506 0,24126232 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,21818506 0,24114639 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,21818506 0,24103056 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,21818506 0,24091485 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,22351786 0,24668477 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,22351786 0,24656646 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,22351786 0,24644826 ! learning GO:0007612 67 37 0,000 0,22351786 0,24633017 ! ion transmembrane transport GO:0034220 56 37 0,000 0,22351786 0,2462122 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,22351786 0,24609434 ! regulation of protein secretion GO:0050708 51 37 0,000 0,22351786 0,24597659 ! amino acid activation GO:0043038 52 37 0,000 0,22351786 0,24585895 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,22351786 0,24574143 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,22881458 0,25144459 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,22881458 0,25132452 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,22881458 0,25120455 ! phagocytosis GO:0006909 60 38 0,000 0,22881458 0,2510847 ! mesenchymal cell development GO:0014031 64 38 0,000 0,22881458 0,25096497 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 0,000 0,22881458 0,25084535 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,23407548 0,25649052 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,23407548 0,25636838 ! male sex differentiation GO:0046661 53 39 0,000 0,23407548 0,25624636 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,23407548 0,25612445 ! chromatin remodeling GO:0006338 68 39 0,000 0,23407548 0,25600266 ! developmental growth GO:0048589 62 39 0,000 0,23407548 0,25588099 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,23930078 0,26146879 ! regulation of tube size GO:0035150 60 40 0,000 0,23930078 0,26134463 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,23930078 0,2612206 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,23930078 0,26109668 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,23930078 0,26097288 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,23930078 0,26084919 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,23930078 0,26072563 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,24449074 0,26625412 ! striated muscle contraction GO:0006941 62 41 0,000 0,24449074 0,26612811 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,24449074 0,26600222 ! biopolymer methylation GO:0043414 62 41 0,000 0,24449074 0,26587645 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,24449074 0,2657508 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,24964558 0,27122571 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,24964558 0,27109766 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,24964558 0,27096972 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,24964558 0,2708419 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,24964558 0,27071421 ! excretion GO:0007588 63 42 0,000 0,24964558 0,27058663 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,24964558 0,27045918 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,24964558 0,27033184 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,24964558 0,27020463 ! regulation of cell shape GO:0008360 78 42 0,000 0,24964558 0,27007753 ! neuromuscular process GO:0050905 79 43 0,000 0,25476555 0,27548696 ! tRNA processing GO:0008033 49 43 0,000 0,25476555 0,2753575 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,25476555 0,27522816 ! vesicle organization GO:0016050 79 43 0,000 0,25476555 0,27509895 ! methylation GO:0032259 64 43 0,000 0,25476555 0,27496985 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,25985087 0,28032692 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,25985087 0,28019549 ! regulation of ion transport GO:0043269 57 44 0,000 0,25985087 0,28006419 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,25985087 0,27993302 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,26490177 0,28524067 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,26490177 0,2851072 ! cell recognition GO:0008037 58 45 0,000 0,26490177 0,28497385 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,2699185 0,29023495 ! cell redox homeostasis GO:0045454 63 46 0,000 0,2699185 0,29009933 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,2699185 0,28996383 ! regulation of ossification GO:0030278 71 46 0,000 0,2699185 0,28982846 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,2699185 0,28969321 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,27490128 0,29490342 ! viral infectious cycle GO:0019058 71 47 0,000 0,27490128 0,29476594 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,27490128 0,29462858 ! endocrine system development GO:0035270 83 47 0,000 0,27490128 0,29449136 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,27490128 0,29435426 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,27490128 0,29421728 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,27490128 0,29408044 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,27490128 0,29394372 ! chloride transport GO:0006821 67 48 0,000 0,27985033 0,29909655 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,27985033 0,29895762 ! gastrulation GO:0007369 73 48 0,000 0,27985033 0,29881883 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,27985033 0,29868017 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,27985033 0,29854164 ! regulation of endocytosis GO:0030100 63 48 0,000 0,27985033 0,29840323 ! nuclear export GO:0051168 69 48 0,000 0,27985033 0,29826495 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,27985033 0,2981268 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,28476589 0,30322294 ! sensory perception of smell GO:0007608 61 49 0,000 0,28476589 0,30308262 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,28476589 0,30294244 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,28476589 0,30280238 ! RNA elongation GO:0006354 62 49 0,000 0,28476589 0,30266245 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,28476589 0,30252265 ! germ cell development GO:0007281 68 49 0,000 0,28476589 0,30238298 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,28476589 0,30224344 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,28476589 0,30210403 ! maintenance of location GO:0051235 84 49 0,000 0,28476589 0,30196475 ! regulation of actin filament length GO:0030832 72 50 0,000 0,28964817 0,30700037 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,28964817 0,30685896 ! proton transport GO:0015992 75 50 0,000 0,28964817 0,30671768 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,28964817 0,30657653 ! positive regulation of secretion GO:0051047 71 51 0,000 0,29449741 0,3115658 ! hydrogen transport GO:0006818 77 51 0,000 0,29449741 0,31142255 ! adult behavior GO:0030534 80 51 0,000 0,29449741 0,31127943 ! transition metal ion transport GO:0000041 74 52 0,000 0,29931382 0,31622498 ! regulation of cellular component size GO:0032535 74 52 0,000 0,29931382 0,31607979 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,29931382 0,31593473 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,30409762 0,32083694 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,30409762 0,32068983 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,30409762 0,32054286 ! kidney development GO:0001822 90 53 0,000 0,30409762 0,32039602 ! amino acid transport GO:0006865 84 54 0,000 0,30884903 0,3252531 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,30884903 0,32510424 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,30884903 0,32495552 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,30884903 0,32480694 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,31356827 0,3296193 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,31356827 0,32946872 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,31825556 0,334241 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,32291111 0,33897561 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,32291111 0,33882096 ! camera-type eye development GO:0043010 88 57 0,000 0,32291111 0,33866646 ! secondary metabolic process GO:0019748 84 57 0,000 0,32291111 0,3385121 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,32753513 0,3432031 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,32753513 0,34304681 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,33212784 0,34769869 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,33212784 0,34754051 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,33212784 0,34738246 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,33668944 0,35199351 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,33668944 0,35183358 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,33668944 0,3516738 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,33668944 0,35151417 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,34122015 0,35608273 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,34122015 0,35592124 ! urogenital system development GO:0001655 101 61 0,000 0,34122015 0,3557599 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,34122015 0,3555987 ! extracellular matrix organization GO:0030198 103 61 0,000 0,34122015 0,35543765 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,34122015 0,35527675 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,34572016 0,35979927 ! neurotransmitter transport GO:0006836 81 62 0,000 0,34572016 0,35963653 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,34572016 0,35947395 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,3501897 0,36395676 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,35462896 0,36840407 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,35462896 0,36823774 ! defense response to bacterium GO:0042742 73 65 0,000 0,35903814 0,37264789 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,35903814 0,3724798 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,35903814 0,37231187 ! activation of immune response GO:0002253 83 65 0,000 0,35903814 0,37214408 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,36341745 0,37651358 ! antigen processing and presentation GO:0019882 96 66 0,000 0,36341745 0,37634405 ! regulation of immune effector process GO:0002697 101 66 0,000 0,36341745 0,37617468 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,36776709 0,38050576 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,36776709 0,38033467 ! acute inflammatory response GO:0002526 92 68 0,000 0,37208726 0,38462953 ! learning or memory GO:0007611 123 68 0,000 0,37208726 0,38445674 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,37208726 0,3842841 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,37208726 0,38411162 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,37208726 0,3839393 ! inorganic anion transport GO:0015698 93 68 0,000 0,37208726 0,38376713 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,37637815 0,38801871 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,37637815 0,38784487 ! humoral immune response GO:0006959 86 70 0,000 0,38063997 0,39206087 ! eye development GO:0001654 111 70 0,000 0,38063997 0,39188537 ! amine transport GO:0015837 101 70 0,000 0,38063997 0,39171003 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,38063997 0,39153485 ! muscle cell differentiation GO:0042692 104 71 0,000 0,3848729 0,39571197 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,3848729 0,39553515 ! regulation of blood pressure GO:0008217 107 73 0,000 0,3932529 0,4039668 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,3932529 0,40378646 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,3932529 0,40360628 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,39740034 0,407681 ! digestion GO:0007586 97 74 0,000 0,39740034 0,40749924 ! blood coagulation GO:0007596 116 75 0,000 0,40151968 0,41153978 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,40151968 0,41135646 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,40151968 0,41117331 ! tRNA metabolic process GO:0006399 95 76 0,000 0,40561109 0,41517824 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,40561109 0,41499355 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,40967476 0,41896485 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,40967476 0,41877864 ! protein ubiquitination GO:0016567 125 77 0,000 0,40967476 0,4185926 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,40967476 0,41840673 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,40967476 0,41822102 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,41371088 0,42215396 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,41371088 0,42196675 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,41771964 0,42586665 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,41771964 0,42567797 ! regulation of lyase activity GO:0051339 133 79 0,000 0,41771964 0,42548945 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,41771964 0,42530109 ! chromatin assembly GO:0031497 102 80 0,000 0,42170121 0,42916495 GO:0006334|nucleosome assembly, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,42170121 0,42897514 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,42565579 0,43280651 ! hemostasis GO:0007599 125 81 0,000 0,42565579 0,43261525 ! mRNA transport GO:0051028 121 81 0,000 0,42565579 0,43242417 ! vitamin metabolic process GO:0006766 103 81 0,000 0,42565579 0,43223325 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,43348468 0,43998886 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,43735934 0,44372584 ! sterol metabolic process GO:0016125 120 84 0,000 0,43735934 0,4435302 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,44120773 0,44723569 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,44503001 0,45091147 ! nucleosome organization GO:0034728 114 87 0,000 0,44882637 0,45455775 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,44882637 0,45435768 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,44882637 0,45415779 ! female pregnancy GO:0007565 130 87 0,000 0,44882637 0,45395807 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,45259698 0,45757057 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,45259698 0,45736953 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,45259698 0,45716866 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,45259698 0,45696797 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,456342 0,46054699 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,456342 0,460345 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,46006162 0,46389378 ! hormone metabolic process GO:0042445 121 90 0,000 0,46006162 0,4636905 ! RNA localization GO:0006403 135 91 0,000 0,463756 0,46720928 ! ATP metabolic process GO:0046034 137 91 0,000 0,463756 0,46700473 ! response to virus GO:0009615 122 91 0,000 0,463756 0,46680035 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,46742531 0,47028793 ! positive regulation of immune response GO:0050778 121 92 0,000 0,46742531 0,4700823 ! sulfur metabolic process GO:0006790 118 92 0,000 0,46742531 0,46987684 ! electron transport chain GO:0022900 123 94 0,000 0,47468941 0,47697058 ! response to oxidative stress GO:0006979 141 94 0,000 0,47468941 0,47676229 ! carboxylic acid transport GO:0046942 147 95 0,000 0,47828453 0,48016343 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,48185526 0,48353712 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,48185526 0,48332625 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,48540174 0,48667132 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,48540174 0,48645926 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,49589742 0,49676135 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,49589742 0,49654509 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,49589742 0,49632901 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,49589742 0,49611312 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,49589742 0,49589742