pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6558-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! carbohydrate homeostasis GO:0033500 53 38 7,000 3,526E-11 8,483E-08 GO:0042593|glucose homeostasis, ! organ growth GO:0035265 15 7 4,000 1,091E-10 1,313E-07 ! positive regulation of MAP kinase activity GO:0043406 160 93 9,000 1,281E-10 1,027E-07 ! cell cycle checkpoint GO:0000075 137 69 8,000 1,891E-10 1,137E-07 ! DNA damage checkpoint GO:0000077 71 33 6,000 5,842E-10 2,811E-07 ! positive regulation of hormone secretion GO:0046887 32 19 5,000 7,293E-10 2,925E-07 ! DNA integrity checkpoint GO:0031570 75 36 6,000 1,125E-09 3,868E-07 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 4,000 1,292E-09 3,884E-07 ! interphase of mitotic cell cycle GO:0051329 209 95 8,000 3,461E-09 9,253E-07 ! activation of MAPK activity GO:0000187 115 67 7,000 4,096E-09 9,856E-07 ! interphase GO:0051325 213 98 8,000 4,569E-09 9,994E-07 ! regulation of insulin secretion GO:0050796 37 25 5,000 4,63E-09 9,283E-07 ! regulation of peptide secretion GO:0002791 47 29 5,000 1,219E-08 2,256E-06 ! cellular response to hormone stimulus GO:0032870 167 82 7,000 2,084E-08 3,582E-06 ! regulation of multicellular organism growth GO:0040014 85 55 6,000 2,502E-08 4,013E-06 ! negative regulation of transport GO:0051051 153 84 7,000 2,525E-08 3,798E-06 ! regulation of protein export from nucleus GO:0046825 10 7 3,000 3,305E-08 4,678E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 3,305E-08 4,418E-06 GO:0046676|negative regulation of insulin secretion, ! DNA damage response, signal transduction GO:0042770 128 60 6,000 4,65E-08 5,889E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 6,582E-08 7,918E-06 ! regulation of hormone secretion GO:0046883 62 40 5,000 9,359E-08 1,072E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 1,013E-07 1,108E-05 ! negative regulation of kinase activity GO:0033673 131 68 6,000 1,124E-07 1,176E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 1,179E-07 1,182E-05 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 1,179E-07 1,135E-05 ! negative regulation of transferase activity GO:0051348 140 72 6,000 1,676E-07 1,551E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 1,941E-07 1,729E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 2,221E-07 1,909E-05 ! fat cell differentiation GO:0045444 50 27 4,000 3,83E-07 3,178E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 4,573E-07 3,668E-05 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of growth GO:0045926 155 84 6,000 4,872E-07 3,781E-05 ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 9,167E-07 6,892E-05 ! positive regulation of secretion GO:0051047 95 59 5,000 1,006E-06 7,335E-05 ! response to peptide hormone stimulus GO:0043434 122 61 5,000 1,228E-06 8,692E-05 ! negative regulation of bone remodeling GO:0046851 33 15 3,000 1,245E-06 8,556E-05 ! negative regulation of secretion GO:0051048 63 35 4,000 1,485E-06 9,926E-05 ! cell cycle arrest GO:0007050 213 100 6,000 1,597E-06 1,038E-04 ! negative regulation of tissue remodeling GO:0034104 36 16 3,000 1,652E-06 1,046E-04 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 1,722E-06 1,062E-04 ! L-serine biosynthetic process GO:0006564 6 5 2,000 1,722E-06 1,036E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 1,976E-06 1,16E-04 ! negative regulation of cell growth GO:0030308 132 67 5,000 2,147E-06 1,23E-04 ! negative regulation of hormone secretion GO:0046888 25 17 3,000 2,151E-06 1,204E-04 ! negative regulation of cell size GO:0045792 134 69 5,000 2,555E-06 1,397E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 3,429E-06 1,833E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 4,247E-06 2,221E-04 ! pancreas development GO:0031016 35 20 3,000 4,322E-06 2,212E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 4,322E-06 2,166E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 5,315E-06 2,61E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 3,000 5,315E-06 2,558E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 5,966E-06 2,815E-04 ! fibrinolysis GO:0042730 10 7 2,000 5,976E-06 2,765E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 5,976E-06 2,713E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 5,976E-06 2,663E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 5,976E-06 2,614E-04 ! regulation of chemotaxis GO:0050920 40 22 3,000 6,468E-06 2,779E-04 ! regulation of inflammatory response GO:0050727 75 48 4,000 7,386E-06 3,118E-04 ! regulation of behavior GO:0050795 43 24 3,000 9,314E-06 3,864E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 9,314E-06 3,798E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 9,522E-06 3,818E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 9,522E-06 3,756E-04 ! positive regulation of growth GO:0045927 90 52 4,000 1,101E-05 4,272E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 1,104E-05 4,216E-04 ! response to UV GO:0009411 104 53 4,000 1,21E-05 4,549E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,299E-05 4,808E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,299E-05 4,735E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of developmental growth GO:0048638 15 9 2,000 1,422E-05 5,108E-04 ! negative regulation of multicellular organismal process GO:0051241 166 93 5,000 1,454E-05 5,145E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 1,518E-05 5,294E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 1,518E-05 5,218E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,734E-05 5,876E-04 ! regulation of bone remodeling GO:0046850 137 57 4,000 1,734E-05 5,794E-04 ! positive regulation of cell migration GO:0030335 126 57 4,000 1,734E-05 5,715E-04 ! regulation of protein localization GO:0032880 176 97 5,000 1,851E-05 6,017E-04 ! regulation of tissue remodeling GO:0034103 140 58 4,000 1,889E-05 6,06E-04 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 2,024E-05 6,406E-04 ! L-serine metabolic process GO:0006563 18 10 2,000 2,024E-05 6,323E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,024E-05 6,242E-04 ! regulation of homeostatic process GO:0032844 134 62 4,000 2,62E-05 7,979E-04 ! triglyceride metabolic process GO:0006641 43 31 3,000 2,675E-05 8,044E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,771E-05 8,231E-04 ! negative regulation of ossification GO:0030279 26 11 2,000 2,771E-05 8,13E-04 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 2,771E-05 8,032E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,771E-05 7,937E-04 GO:0010829|negative regulation of glucose transport, ! multicellular organism reproduction GO:0032504 111 64 4,000 3,059E-05 8,659E-04 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 4,000 3,059E-05 8,558E-04 ! focal adhesion formation GO:0048041 35 12 2,000 3,679E-05 1,018E-03 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 3,679E-05 1,006E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 3,823E-05 1,033E-03 ! regulation of striated muscle tissue development GO:0016202 69 34 3,000 3,891E-05 1,04E-03 ! regulation of muscle development GO:0048634 70 35 3,000 4,374E-05 1,156E-03 ! neutral lipid metabolic process GO:0006638 50 35 3,000 4,374E-05 1,144E-03 GO:0006639|acylglycerol metabolic process, ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 4,763E-05 1,232E-03 ! androgen receptor signaling pathway GO:0030521 74 36 3,000 4,899E-05 1,254E-03 ! meiosis I GO:0007127 65 37 3,000 5,469E-05 1,385E-03 ! glycerol ether metabolic process GO:0006662 53 37 3,000 5,469E-05 1,371E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 6,037E-05 1,498E-03 ! response to gamma radiation GO:0010332 28 14 2,000 6,037E-05 1,482E-03 ! meiosis GO:0007126 121 74 4,000 6,178E-05 1,501E-03 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 4,000 6,589E-05 1,585E-03 ! organic ether metabolic process GO:0018904 55 39 3,000 6,752E-05 1,608E-03 ! mesenchymal cell development GO:0014031 87 40 3,000 7,469E-05 1,762E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of skeletal muscle tissue development GO:0048641 35 15 2,000 7,516E-05 1,756E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 7,516E-05 1,739E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 7,516E-05 1,722E-03 ! hormone-mediated signaling GO:0009755 74 41 3,000 8,24E-05 1,87E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 8,45E-05 1,9E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 9,068E-05 2,02E-03 ! activation of MAPKK activity GO:0000186 35 16 2,000 9,212E-05 2,033E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 9,52E-05 2,082E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 4,000 9,52E-05 2,064E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 9,955E-05 2,138E-03 ! response to oxygen levels GO:0070482 176 83 4,000 1,069E-04 2,276E-03 ! myoblast differentiation GO:0045445 45 17 2,000 1,114E-04 2,351E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,114E-04 2,331E-03 ! regulation of protein binding GO:0043393 33 17 2,000 1,114E-04 2,311E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,114E-04 2,291E-03 ! negative regulation of blood coagulation GO:0030195 24 17 2,000 1,114E-04 2,271E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 1,114E-04 2,252E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,299E-04 2,605E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,331E-04 2,647E-03 ! regulation of protein transport GO:0051223 154 87 4,000 1,336E-04 2,635E-03 GO:0070201|regulation of establishment of protein localization, ! positive regulation of defense response GO:0031349 76 47 3,000 1,414E-04 2,766E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,536E-04 2,98E-03 ! G1 phase GO:0051318 40 19 2,000 1,574E-04 3,03E-03 ! regulation of defense response GO:0031347 149 92 4,000 1,739E-04 3,32E-03 ! regulation of ossification GO:0030278 117 50 3,000 1,802E-04 3,413E-03 ! response to alkaloid GO:0043279 38 20 2,000 1,845E-04 3,467E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,845E-04 3,44E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,845E-04 3,414E-03 GO:0010827|regulation of glucose transport, ! negative regulation of translation GO:0017148 29 20 2,000 1,845E-04 3,388E-03 ! negative regulation of coagulation GO:0050819 29 20 2,000 1,845E-04 3,362E-03 ! regulation of muscle contraction GO:0006937 81 52 3,000 2,1E-04 3,798E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 2,143E-04 3,848E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,143E-04 3,82E-03 ! cell aging GO:0007569 44 21 2,000 2,143E-04 3,792E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 2,45E-04 4,304E-03 GO:0060538|skeletal muscle organ development, ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,471E-04 4,309E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 2,471E-04 4,278E-03 ! skeletal muscle fiber development GO:0048741 111 56 3,000 2,799E-04 4,811E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 2,83E-04 4,83E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 2,83E-04 4,796E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 2,83E-04 4,762E-03 ! muscle fiber development GO:0048747 112 57 3,000 2,998E-04 5,008E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 2,998E-04 4,974E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,096E-04 5,102E-03 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 1,000 3,096E-04 5,067E-03 ! adaptation of signaling pathway GO:0022401 7 5 1,000 3,096E-04 5,033E-03 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,096E-04 4,999E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,096E-04 4,966E-03 ! microvillus organization GO:0032528 7 5 1,000 3,096E-04 4,933E-03 GO:0030033|microvillus assembly, ! muscle cell migration GO:0014812 8 5 1,000 3,096E-04 4,9E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,096E-04 4,868E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,096E-04 4,837E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 3,096E-04 4,805E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,096E-04 4,775E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,096E-04 4,744E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 3,096E-04 4,714E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,096E-04 4,684E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 3,096E-04 4,655E-03 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 3,096E-04 4,626E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 3,096E-04 4,598E-03 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 1,000 3,096E-04 4,57E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 3,221E-04 4,726E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 3,221E-04 4,697E-03 ! protein tetramerization GO:0051262 52 24 2,000 3,221E-04 4,669E-03 ! myelination GO:0042552 45 25 2,000 3,646E-04 5,252E-03 ! regulation of blood coagulation GO:0030193 40 25 2,000 3,646E-04 5,221E-03 ! regulation of heart contraction GO:0008016 110 60 3,000 3,652E-04 5,2E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,652E-04 5,169E-03 ! negative regulation of response to stimulus GO:0048585 100 60 3,000 3,652E-04 5,139E-03 ! positive regulation of nuclear division GO:0051785 40 26 2,000 4,104E-04 5,741E-03 GO:0045840|positive regulation of mitosis, ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 4,404E-04 6,124E-03 ! mitochondrial membrane organization GO:0007006 57 27 2,000 4,598E-04 6,358E-03 ! response to toxin GO:0009636 47 27 2,000 4,598E-04 6,322E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 4,598E-04 6,286E-03 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 4,626E-04 6,289E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 4,626E-04 6,254E-03 ! hyperosmotic response GO:0006972 9 6 1,000 4,626E-04 6,219E-03 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 1,000 4,626E-04 6,184E-03 ! male sex determination GO:0030238 15 6 1,000 4,626E-04 6,15E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 4,626E-04 6,116E-03 GO:0051653|spindle localization, ! monocyte differentiation GO:0030224 12 6 1,000 4,626E-04 6,083E-03 ! neural nucleus development GO:0048857 14 6 1,000 4,626E-04 6,05E-03 ! astrocyte development GO:0014002 15 6 1,000 4,626E-04 6,017E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 4,626E-04 5,985E-03 ! Schwann cell development GO:0014044 15 6 1,000 4,626E-04 5,953E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 4,626E-04 5,921E-03 ! negative regulation of multicellular organism growth GO:0040015 8 6 1,000 4,626E-04 5,89E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,626E-04 5,859E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,626E-04 5,828E-03 ! negative regulation of smooth muscle contraction GO:0045986 12 6 1,000 4,626E-04 5,798E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 5,129E-04 6,394E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 5,697E-04 7,066E-03 ! tissue homeostasis GO:0001894 48 29 2,000 5,697E-04 7,029E-03 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 2,000 5,697E-04 6,994E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 5,891E-04 7,195E-03 ! cell junction assembly GO:0034329 78 30 2,000 6,304E-04 7,661E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 6,304E-04 7,622E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 6,304E-04 7,584E-03 GO:0008366|axon ensheathment, ! regulation of helicase activity GO:0051095 15 7 1,000 6,453E-04 7,724E-03 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 6,453E-04 7,686E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,453E-04 7,648E-03 ! mRNA stabilization GO:0048255 18 7 1,000 6,453E-04 7,611E-03 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,453E-04 7,574E-03 ! lipoprotein transport GO:0042953 14 7 1,000 6,453E-04 7,537E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 6,453E-04 7,501E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! response to dietary excess GO:0002021 8 7 1,000 6,453E-04 7,465E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 6,453E-04 7,429E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 1,000 6,453E-04 7,393E-03 ! response to tumor cell GO:0002347 13 7 1,000 6,453E-04 7,358E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 6,453E-04 7,324E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 6,453E-04 7,289E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 6,453E-04 7,255E-03 ! endosome to lysosome transport GO:0008333 11 7 1,000 6,453E-04 7,222E-03 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 6,951E-04 7,743E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 7,639E-04 8,469E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 7,639E-04 8,43E-03 ! peripheral nervous system development GO:0007422 64 32 2,000 7,639E-04 8,392E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 8,368E-04 9,151E-03 GO:0060326|cell chemotaxis, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 1,000 8,572E-04 9,333E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 8,572E-04 9,291E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 8,572E-04 9,249E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,572E-04 9,208E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,572E-04 9,167E-03 ! pigment granule organization GO:0048753 16 8 1,000 8,572E-04 9,126E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 8,572E-04 9,086E-03 ! astrocyte differentiation GO:0048708 18 8 1,000 8,572E-04 9,046E-03 ! ER overload response GO:0006983 12 8 1,000 8,572E-04 9,007E-03 ! regulation of pigmentation during development GO:0048070 24 8 1,000 8,572E-04 8,968E-03 ! melanin metabolic process GO:0006582 15 8 1,000 8,572E-04 8,929E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 8,572E-04 8,89E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,572E-04 8,852E-03 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 8,572E-04 8,814E-03 ! positive regulation of vasodilation GO:0045909 13 8 1,000 8,572E-04 8,777E-03 ! negative regulation of muscle contraction GO:0045932 15 8 1,000 8,572E-04 8,74E-03 ! Schwann cell differentiation GO:0014037 19 8 1,000 8,572E-04 8,703E-03 ! response to UV-B GO:0010224 16 8 1,000 8,572E-04 8,666E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 8,572E-04 8,63E-03 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 8,572E-04 8,594E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 8,572E-04 8,558E-03 ! negative regulation of calcium ion transport GO:0051926 13 8 1,000 8,572E-04 8,523E-03 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 1,000 8,572E-04 8,488E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 8,572E-04 8,453E-03 ! placenta development GO:0001890 53 34 2,000 9,14E-04 8,976E-03 ! blood coagulation GO:0007596 146 78 3,000 9,88E-04 9,663E-03 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 3,000 9,88E-04 9,624E-03 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 9,956E-04 9,659E-03 ! activation of protein kinase activity GO:0032147 147 79 3,000 1,036E-03 0,01001222 ! cell junction organization GO:0034330 86 36 2,000 1,082E-03 0,01040977 ! muscle cell differentiation GO:0042692 159 80 3,000 1,086E-03 0,01040994 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,098E-03 0,01048431 ! cell proliferation in forebrain GO:0021846 15 9 1,000 1,098E-03 0,01044287 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,098E-03 0,01040175 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 21 9 1,000 1,098E-03 0,01036096 ! cerebral cortex cell migration GO:0021795 15 9 1,000 1,098E-03 0,01032049 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,098E-03 0,01028033 ! T cell selection GO:0045058 23 9 1,000 1,098E-03 0,01024049 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,098E-03 0,01020095 ! behavioral fear response GO:0001662 22 9 1,000 1,098E-03 0,01016171 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,098E-03 0,01012278 ! protein heterooligomerization GO:0051291 16 9 1,000 1,098E-03 0,01008414 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,098E-03 0,0100458 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,098E-03 0,01000775 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,098E-03 9,97E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,098E-03 9,933E-03 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,137E-03 0,01024992 ! tissue remodeling GO:0048771 76 37 2,000 1,172E-03 0,0105241 ! response to drug GO:0042493 143 82 3,000 1,191E-03 0,01064915 ! lipid homeostasis GO:0055088 67 38 2,000 1,268E-03 0,01129505 ! hemostasis GO:0007599 158 84 3,000 1,302E-03 0,01156037 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,368E-03 0,01209656 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,368E-03 0,01205269 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,368E-03 0,0120087 ! negative regulation of blood pressure GO:0045776 26 10 1,000 1,368E-03 0,01196504 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,368E-03 0,01192168 ! positive regulation of heart contraction GO:0045823 16 10 1,000 1,368E-03 0,01187865 ! lung alveolus development GO:0048286 26 10 1,000 1,368E-03 0,01183592 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,368E-03 0,01179349 ! B cell proliferation GO:0042100 18 10 1,000 1,368E-03 0,01175137 ! regulation of sodium ion transport GO:0002028 21 10 1,000 1,368E-03 0,01170955 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,368E-03 0,01166803 ! regulation of bone resorption GO:0045124 25 10 1,000 1,368E-03 0,0116268 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,368E-03 0,01158586 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,368E-03 0,01154521 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,368E-03 0,01150484 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,368E-03 0,01146476 ! response to nicotine GO:0035094 20 10 1,000 1,368E-03 0,01142495 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,368E-03 0,01138541 ! localization within membrane GO:0051668 20 10 1,000 1,368E-03 0,01134615 ! tube morphogenesis GO:0035239 176 86 3,000 1,421E-03 0,0117463 ! mitochondrion organization GO:0007005 148 86 3,000 1,421E-03 0,01170607 ! gland development GO:0048732 206 88 3,000 1,547E-03 0,01270009 ! gliogenesis GO:0042063 88 41 2,000 1,582E-03 0,01294724 ! T cell differentiation GO:0030217 81 41 2,000 1,582E-03 0,01290335 ! regulation of cell adhesion GO:0030155 212 89 3,000 1,612E-03 0,01310607 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,665E-03 0,0134908 ! telencephalon cell migration GO:0022029 20 11 1,000 1,665E-03 0,01344552 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,665E-03 0,01340056 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,665E-03 0,01335589 ! blood vessel remodeling GO:0001974 29 11 1,000 1,665E-03 0,01331152 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,665E-03 0,01326744 ! bone resorption GO:0045453 16 11 1,000 1,665E-03 0,01322365 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,665E-03 0,01318015 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,665E-03 0,01313694 ! temperature homeostasis GO:0001659 17 11 1,000 1,665E-03 0,01309401 ! nitric oxide metabolic process GO:0046209 15 11 1,000 1,665E-03 0,01305136 GO:0006809|nitric oxide biosynthetic process, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,665E-03 0,01300898 ! oocyte differentiation GO:0009994 18 11 1,000 1,665E-03 0,01296688 ! thymus development GO:0048538 27 11 1,000 1,665E-03 0,01292505 ! regulation of embryonic development GO:0045995 27 11 1,000 1,665E-03 0,01288349 ! neuron migration GO:0001764 79 42 2,000 1,697E-03 0,01308498 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 1,697E-03 0,01304317 ! regulation of membrane potential GO:0042391 164 93 3,000 1,895E-03 0,01452031 ! double-strand break repair GO:0006302 81 44 2,000 1,942E-03 0,0148297 ! B cell differentiation GO:0030183 107 44 2,000 1,942E-03 0,01478277 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,991E-03 0,01511172 ! virus-host interaction GO:0019048 29 12 1,000 1,991E-03 0,0150642 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,991E-03 0,01501697 ! forebrain cell migration GO:0021885 21 12 1,000 1,991E-03 0,01497005 ! fear response GO:0042596 26 12 1,000 1,991E-03 0,01492341 ! histone acetylation GO:0016573 26 12 1,000 1,991E-03 0,01487706 ! gland morphogenesis GO:0022612 29 12 1,000 1,991E-03 0,014831 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,991E-03 0,01478523 ! T cell homeostasis GO:0043029 25 12 1,000 1,991E-03 0,01473974 ! spleen development GO:0048536 22 12 1,000 1,991E-03 0,01469452 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,991E-03 0,01464959 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,991E-03 0,01460492 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,991E-03 0,01456053 ! response to cold GO:0009409 17 12 1,000 1,991E-03 0,01451641 ! leukocyte migration GO:0050900 68 45 2,000 2,072E-03 0,01505906 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 2,072E-03 0,0150137 ! leukocyte differentiation GO:0002521 202 96 3,000 2,128E-03 0,01537707 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,207E-03 0,0158997 ! negative regulation of cell migration GO:0030336 115 46 2,000 2,207E-03 0,01585224 ! pigmentation GO:0043473 100 46 2,000 2,207E-03 0,01580506 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,21E-03 0,01577966 ! hormone metabolic process GO:0042445 157 97 3,000 2,21E-03 0,01573298 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,344E-03 0,01663882 GO:0000725|recombinational repair, ! endocrine pancreas development GO:0031018 22 13 1,000 2,344E-03 0,01658989 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,344E-03 0,01654124 ! response to X-ray GO:0010165 25 13 1,000 2,344E-03 0,01649287 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,344E-03 0,01644479 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,344E-03 0,01639698 ! regulation of cellular pH GO:0030641 22 13 1,000 2,344E-03 0,01634945 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,344E-03 0,0163022 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,344E-03 0,01625522 ! vascular process in circulatory system GO:0003018 80 47 2,000 2,348E-03 0,01623387 ! mitochondrial transport GO:0006839 82 48 2,000 2,494E-03 0,01719593 ! activation of caspase activity GO:0006919 84 48 2,000 2,494E-03 0,0171468 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,494E-03 0,01709794 ! regulation of action potential GO:0001508 95 49 2,000 2,646E-03 0,01808707 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,646E-03 0,01803583 ! response to temperature stimulus GO:0009266 76 49 2,000 2,646E-03 0,01798488 ! endocrine system development GO:0035270 104 49 2,000 2,646E-03 0,01793422 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,725E-03 0,01841698 ! hair follicle morphogenesis GO:0031069 26 14 1,000 2,725E-03 0,01836539 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 2,725E-03 0,01831409 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,725E-03 0,01826308 ! positive regulation of bone mineralization GO:0030501 29 14 1,000 2,725E-03 0,01821235 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 2,725E-03 0,0181619 ! regulation of RNA stability GO:0043487 32 14 1,000 2,725E-03 0,01811173 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 2,967E-03 0,01966301 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,967E-03 0,01960899 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 2,000 2,967E-03 0,01955527 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 3,133E-03 0,02059374 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! pituitary gland development GO:0021983 29 15 1,000 3,133E-03 0,02053763 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,133E-03 0,02048182 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,133E-03 0,02042631 ! positive regulation of biomineral formation GO:0070169 30 15 1,000 3,133E-03 0,0203711 ! regulation of vasodilation GO:0042312 26 15 1,000 3,133E-03 0,0203162 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 3,133E-03 0,02026158 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,133E-03 0,02020726 ! regulation of angiogenesis GO:0045765 114 52 2,000 3,135E-03 0,02017044 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 3,135E-03 0,02011665 ! cartilage development GO:0051216 90 52 2,000 3,135E-03 0,02006315 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 3,31E-03 0,02112394 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,567E-03 0,02270477 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 3,567E-03 0,02264487 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 3,567E-03 0,02258527 ! bone remodeling GO:0046849 27 16 1,000 3,567E-03 0,022526 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 3,567E-03 0,02246703 ! response to osmotic stress GO:0006970 25 16 1,000 3,567E-03 0,02240837 ! lysosomal transport GO:0007041 26 16 1,000 3,567E-03 0,02235001 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 3,567E-03 0,02229196 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,567E-03 0,02223421 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,567E-03 0,02217676 ! defense response to virus GO:0051607 37 16 1,000 3,567E-03 0,0221196 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,677E-03 0,0227404 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 3,677E-03 0,02268209 ! negative regulation of cell motion GO:0051271 134 55 2,000 3,677E-03 0,02262408 ! regulation of DNA replication GO:0006275 101 56 2,000 3,869E-03 0,02374645 ! positive regulation of organelle organization GO:0010638 100 56 2,000 3,869E-03 0,02368602 ! metencephalon development GO:0022037 30 17 1,000 4,028E-03 0,02459642 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,028E-03 0,02453415 ! inositol metabolic process GO:0006020 28 17 1,000 4,028E-03 0,02447219 ! glial cell development GO:0021782 27 17 1,000 4,028E-03 0,02441055 ! limbic system development GO:0021761 36 17 1,000 4,028E-03 0,02434922 ! regulation of viral genome replication GO:0045069 28 17 1,000 4,028E-03 0,02428819 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,028E-03 0,02422747 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,028E-03 0,02416705 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,028E-03 0,02410694 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,515E-03 0,02695366 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 4,515E-03 0,02688694 ! negative regulation of ion transport GO:0043271 24 18 1,000 4,515E-03 0,02682055 ! epidermis morphogenesis GO:0048730 40 18 1,000 4,515E-03 0,02675449 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 4,515E-03 0,02668875 ! long-chain fatty acid transport GO:0015909 31 18 1,000 4,515E-03 0,02662334 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,515E-03 0,02655825 ! lipid phosphorylation GO:0046834 35 19 1,000 5,027E-03 0,02950166 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,027E-03 0,02942988 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,027E-03 0,02935844 ! cerebral cortex development GO:0021987 36 19 1,000 5,027E-03 0,02928736 ! actin filament bundle formation GO:0051017 42 19 1,000 5,027E-03 0,02921662 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,027E-03 0,02914621 ! negative regulation of defense response GO:0031348 25 19 1,000 5,027E-03 0,02907615 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,027E-03 0,02900642 ! neuromuscular junction development GO:0007528 34 19 1,000 5,027E-03 0,02893703 ! cellular pigmentation GO:0033059 36 19 1,000 5,027E-03 0,02886797 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,027E-03 0,02879924 ! ear development GO:0043583 103 62 2,000 5,151E-03 0,0294368 ! regulation of mitosis GO:0007088 105 63 2,000 5,386E-03 0,03070986 GO:0051783|regulation of nuclear division, ! positive regulation of ossification GO:0045778 47 20 1,000 5,565E-03 0,03165563 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,565E-03 0,03158097 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,565E-03 0,03150666 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 5,565E-03 0,0314327 ! diencephalon development GO:0021536 34 20 1,000 5,565E-03 0,03135909 ! peptidyl-serine modification GO:0018209 43 20 1,000 5,565E-03 0,03128582 ! negative regulation of T cell activation GO:0050868 40 20 1,000 5,565E-03 0,03121289 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 5,565E-03 0,03114031 ! myeloid cell differentiation GO:0030099 111 65 2,000 5,877E-03 0,03280521 ! hindlimb morphogenesis GO:0035137 43 21 1,000 6,129E-03 0,03413324 ! ovarian follicle development GO:0001541 35 21 1,000 6,129E-03 0,03405441 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 6,129E-03 0,03397595 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 6,129E-03 0,03389784 ! vasodilation GO:0042311 39 21 1,000 6,129E-03 0,0338201 ! oogenesis GO:0048477 36 21 1,000 6,129E-03 0,0337427 ! response to cytokine stimulus GO:0034097 63 21 1,000 6,129E-03 0,03366567 ! gut development GO:0048565 39 21 1,000 6,129E-03 0,03358898 ! actin filament organization GO:0007015 148 66 2,000 6,131E-03 0,03352745 ! lung development GO:0030324 144 67 2,000 6,393E-03 0,03487705 ! homeostasis of number of cells GO:0048872 114 67 2,000 6,393E-03 0,03479814 ! positive regulation of bone remodeling GO:0046852 51 22 1,000 6,717E-03 0,03648004 GO:0034105|positive regulation of tissue remodeling, ! regeneration GO:0031099 41 22 1,000 6,717E-03 0,03639788 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 6,717E-03 0,03631608 ! vacuolar transport GO:0007034 36 22 1,000 6,717E-03 0,03623466 ! apoptotic nuclear changes GO:0030262 32 22 1,000 6,717E-03 0,0361536 ! ureteric bud development GO:0001657 43 22 1,000 6,717E-03 0,0360729 ! renal system process GO:0003014 41 22 1,000 6,717E-03 0,03599255 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,717E-03 0,03591257 ! activation of JUN kinase activity GO:0007257 42 22 1,000 6,717E-03 0,03583294 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 6,717E-03 0,03575367 ! respiratory tube development GO:0030323 150 70 2,000 7,216E-03 0,03832637 ! positive regulation of DNA replication GO:0045740 43 23 1,000 7,33E-03 0,03884342 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 7,33E-03 0,03875805 ! response to ethanol GO:0045471 46 23 1,000 7,33E-03 0,03867305 ! sex determination GO:0007530 47 23 1,000 7,33E-03 0,03858843 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 7,33E-03 0,03850417 ! regulation of viral reproduction GO:0050792 38 23 1,000 7,33E-03 0,03842029 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 7,33E-03 0,03833676 ! fatty acid transport GO:0015908 44 23 1,000 7,33E-03 0,0382536 ! platelet activation GO:0030168 37 23 1,000 7,33E-03 0,0381708 ! regulation of bone mineralization GO:0030500 49 23 1,000 7,33E-03 0,03808836 ! B cell activation GO:0042113 160 71 2,000 7,504E-03 0,03890984 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 7,504E-03 0,03882616 ! regulation of caspase activity GO:0043281 122 72 2,000 7,798E-03 0,04026314 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 7,798E-03 0,04017692 ! respiratory system development GO:0060541 153 72 2,000 7,798E-03 0,04009107 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 7,967E-03 0,04086914 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 7,967E-03 0,04078218 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 7,967E-03 0,04069559 ! regulation of transmembrane transport GO:0034762 38 24 1,000 7,967E-03 0,04060937 ! multicellular organismal response to stress GO:0033555 49 24 1,000 7,967E-03 0,04052352 ! lymphocyte proliferation GO:0046651 48 24 1,000 7,967E-03 0,04043803 ! pallium development GO:0021543 49 24 1,000 7,967E-03 0,04035289 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 7,967E-03 0,04026812 ! leukocyte homeostasis GO:0001776 44 24 1,000 7,967E-03 0,0401837 ! regulation of blood pressure GO:0008217 125 73 2,000 8,099E-03 0,04076839 ! exocytosis GO:0006887 133 74 2,000 8,407E-03 0,04223018 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 8,407E-03 0,0421422 ! vasculogenesis GO:0001570 46 25 1,000 8,628E-03 0,04315614 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 8,628E-03 0,0430666 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 8,628E-03 0,04297744 ! negative regulation of DNA replication GO:0008156 42 25 1,000 8,628E-03 0,04288864 ! receptor metabolic process GO:0043112 46 25 1,000 8,628E-03 0,04280021 ! response to starvation GO:0042594 42 25 1,000 8,628E-03 0,04271214 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 8,628E-03 0,04262444 ! negative regulation of cell development GO:0010721 73 25 1,000 8,628E-03 0,04253709 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 8,628E-03 0,04245011 ! regulation of biomineral formation GO:0070167 51 25 1,000 8,628E-03 0,04236347 ! somitogenesis GO:0001756 43 25 1,000 8,628E-03 0,04227719 ! cellular response to nutrient levels GO:0031669 41 25 1,000 8,628E-03 0,04219126 ! neural tube closure GO:0001843 49 25 1,000 8,628E-03 0,04210568 GO:0060606|tube closure, ! liver development GO:0001889 53 25 1,000 8,628E-03 0,04202045 ! cell-matrix adhesion GO:0007160 163 75 2,000 8,722E-03 0,04239515 ! lymphocyte differentiation GO:0030098 167 75 2,000 8,722E-03 0,04230967 ! molting cycle process GO:0022404 50 26 1,000 9,312E-03 0,0450818 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 9,312E-03 0,04499128 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 9,312E-03 0,04490111 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 9,312E-03 0,04481131 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 9,312E-03 0,04472187 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 9,312E-03 0,04463278 ! leukocyte proliferation GO:0070661 52 26 1,000 9,312E-03 0,04454405 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 9,312E-03 0,04445567 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 9,708E-03 0,0462507 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01002062 0,04764743 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01002062 0,04755345 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 1,000 0,01002062 0,04745984 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! male gonad development GO:0008584 44 27 1,000 0,01002062 0,0473666 ! primary neural tube formation GO:0014020 51 27 1,000 0,01002062 0,04727373 ! base-excision repair GO:0006284 41 27 1,000 0,01002062 0,04718122 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01002062 0,04708906 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01004994 0,04713483 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01075198 0,0503293 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01075198 0,05023158 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01075198 0,05013423 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01075198 0,05003726 ! T cell activation GO:0042110 168 81 2,000 0,01075541 0,04995659 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01075541 0,04986034 ! response to nutrient GO:0007584 125 82 2,000 0,01111863 0,05144504 ! regulation of pH GO:0006885 43 29 1,000 0,01150622 0,05313622 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01150622 0,05303442 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01150622 0,05293302 ! sterol biosynthetic process GO:0016126 52 29 1,000 0,01150622 0,052832 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01150622 0,05273137 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01228306 0,05618451 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01228306 0,0560779 ! response to heat GO:0009408 50 30 1,000 0,01228306 0,05597169 ! amine biosynthetic process GO:0009309 138 86 2,000 0,01264195 0,05749819 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01308223 0,05938841 GO:0055092|sterol homeostasis, ! ovulation cycle process GO:0022602 49 31 1,000 0,01308223 0,05927657 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01308223 0,05916514 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01308223 0,05905414 ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01344616 0,06058328 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,01385897 0,06232651 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01390346 0,06240993 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 0,01390346 0,06229371 ! spindle organization GO:0007051 46 32 1,000 0,01390346 0,06217793 ! metanephros development GO:0001656 74 32 1,000 0,01390346 0,06206257 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01390346 0,06194764 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,01390346 0,06183313 ! ovulation cycle GO:0042698 51 32 1,000 0,01390346 0,06171905 ! hindbrain development GO:0030902 61 32 1,000 0,01390346 0,06160539 ! regulation of calcium ion transport GO:0051924 53 32 1,000 0,01390346 0,06149214 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01390346 0,06137931 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01427893 0,06292145 ! post-embryonic development GO:0009791 69 33 1,000 0,01474647 0,06486291 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01474647 0,06474454 ! glial cell differentiation GO:0010001 63 34 1,000 0,015611 0,06841542 ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,015611 0,06829103 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,015611 0,06816709 ! forebrain development GO:0030900 188 95 2,000 0,01648656 0,07185988 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 0,01648656 0,07172993 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01649678 0,07164487 ! female gonad development GO:0008585 58 35 1,000 0,01649678 0,07151578 ! telencephalon development GO:0021537 68 35 1,000 0,01649678 0,07138716 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01649678 0,07125899 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01649678 0,07113129 ! cytokine production GO:0001816 59 35 1,000 0,01649678 0,07100404 ! neural tube formation GO:0001841 67 35 1,000 0,01649678 0,07087725 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01740356 0,07463985 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01740356 0,07450703 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01740356 0,0743747 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01833106 0,07819951 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01833106 0,07806111 ! regulation of protein stability GO:0031647 73 37 1,000 0,01833106 0,07792319 ! pigment metabolic process GO:0042440 80 37 1,000 0,01833106 0,07778576 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01927903 0,08166435 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,01927903 0,08152083 ! regulation of metal ion transport GO:0010959 63 38 1,000 0,01927903 0,08137781 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01927903 0,08123529 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01927903 0,08109327 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01927903 0,08095175 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01927903 0,08081071 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01927903 0,08067017 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01927903 0,08053012 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,01927903 0,08039056 ! mammary gland development GO:0030879 86 39 1,000 0,02024722 0,08428169 ! ear morphogenesis GO:0042471 60 39 1,000 0,02024722 0,08413612 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02024722 0,08399106 ! segmentation GO:0035282 67 39 1,000 0,02024722 0,0838465 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,02024722 0,08370243 ! negative regulation of binding GO:0051100 72 40 1,000 0,02123537 0,08763689 ! cytokinesis GO:0000910 72 40 1,000 0,02123537 0,08748683 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02224323 0,09148243 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02224323 0,09132631 ! female gamete generation GO:0007292 61 41 1,000 0,02224323 0,09117073 ! polyol metabolic process GO:0019751 66 41 1,000 0,02224323 0,09101568 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02327055 0,09505765 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02327055 0,09489653 ! regulation of tube size GO:0035150 71 42 1,000 0,02327055 0,09473596 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,02327055 0,09457594 ! regulation of protein secretion GO:0050708 71 42 1,000 0,02327055 0,09441645 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02431709 0,09849649 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,02431709 0,09833095 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,02431709 0,09816597 ! glucose transport GO:0015758 65 43 1,000 0,02431709 0,09800154 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02431709 0,09783765 ! neural tube development GO:0021915 77 43 1,000 0,02431709 0,09767432 ! activation of adenylate cyclase activity GO:0007190 91 44 1,000 0,02538259 0,10178419 ! hexose transport GO:0008645 67 44 1,000 0,02538259 0,10161483 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,02538259 0,10144604 ! developmental growth GO:0048589 82 44 1,000 0,02538259 0,1012778 ! glycolysis GO:0006096 65 45 1,000 0,02646682 0,10542908 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02646682 0,10525482 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 1,000 0,02756953 0,10945922 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02774594 0,10997816 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02774594 0,10979727 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02774594 0,10961698 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02774594 0,10943728 ! neuron fate determination GO:0048664 7 5 0,000 0,02774594 0,10925817 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02774594 0,10907964 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02774594 0,1089017 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02774594 0,10872433 ! polyol transport GO:0015791 12 5 0,000 0,02774594 0,10854755 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02774594 0,10837133 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02774594 0,10819569 ! response to superoxide GO:0000303 10 5 0,000 0,02774594 0,10802062 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02774594 0,10784611 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02774594 0,10767216 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02774594 0,10749878 ! female meiosis GO:0007143 7 5 0,000 0,02774594 0,10732595 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02774594 0,10715368 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02774594 0,10698196 ! cobalt ion transport GO:0006824 11 5 0,000 0,02774594 0,10681079 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02774594 0,10664016 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02774594 0,10647008 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02774594 0,10630054 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02774594 0,10613154 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02774594 0,10596308 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02774594 0,10579515 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02774594 0,10562775 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02774594 0,10546089 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02774594 0,10529454 ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02774594 0,10512873 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02774594 0,10496343 ! negative chemotaxis GO:0050919 14 5 0,000 0,02774594 0,10479865 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02774594 0,10463439 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02774594 0,10447064 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02774594 0,10430741 ! behavioral response to pain GO:0048266 9 5 0,000 0,02774594 0,10414468 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02774594 0,10398246 ! Notch receptor processing GO:0007220 8 5 0,000 0,02774594 0,10382075 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02774594 0,10365954 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02774594 0,10349882 ! micturition GO:0060073 9 5 0,000 0,02774594 0,10333861 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02774594 0,10317889 ! copulation GO:0007620 9 5 0,000 0,02774594 0,10301966 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02774594 0,10286093 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02774594 0,10270268 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02774594 0,10254492 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02774594 0,10238764 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02774594 0,10223084 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02774594 0,10207453 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02774594 0,10191869 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02774594 0,10176332 ! grooming behavior GO:0007625 6 5 0,000 0,02774594 0,10160843 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02774594 0,10145401 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02774594 0,10130006 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02774594 0,10114658 ! response to protozoan GO:0001562 10 5 0,000 0,02774594 0,10099356 ! lymph vessel development GO:0001945 10 5 0,000 0,02774594 0,100841 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02774594 0,1006889 ! endochondral ossification GO:0001958 16 5 0,000 0,02774594 0,10053726 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02774594 0,10038608 ! parathyroid gland development GO:0060017 13 5 0,000 0,02774594 0,10023535 ! anagen GO:0042640 6 5 0,000 0,02774594 0,10008507 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02774594 0,09993524 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02774594 0,09978586 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02774594 0,09963693 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02774594 0,09948844 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02774594 0,09934039 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02774594 0,09919278 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02774594 0,09904561 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02774594 0,09889888 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02774594 0,09875258 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02774594 0,09860671 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02774594 0,09846127 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02774594 0,09831626 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02774594 0,09817168 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02774594 0,09802752 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02774594 0,09788378 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02774594 0,09774047 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02774594 0,09759757 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02774594 0,0974551 ! histidine catabolic process GO:0006548 6 5 0,000 0,02774594 0,09731303 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02774594 0,09717138 ! valine metabolic process GO:0006573 10 5 0,000 0,02774594 0,09703015 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02774594 0,09688932 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02774594 0,0967489 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02774594 0,09660889 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02774594 0,09646928 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02774594 0,09633007 ! polyol catabolic process GO:0046174 7 5 0,000 0,02774594 0,09619127 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02774594 0,09605286 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02774594 0,09591486 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02774594 0,09577725 ! mitochondrial fission GO:0000266 8 5 0,000 0,02774594 0,09564003 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02774594 0,09550321 ! mRNA transcription GO:0009299 9 5 0,000 0,02774594 0,09536677 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02774594 0,09523073 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02774594 0,09509507 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02774594 0,0949598 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02774594 0,09482492 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02774594 0,09469041 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02774594 0,09455629 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02774594 0,09442255 ! response to food GO:0032094 6 5 0,000 0,02774594 0,09428918 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02774594 0,09415619 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02774594 0,09402358 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02774594 0,09389134 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02774594 0,09375947 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02774594 0,09362797 ! forebrain neuron development GO:0021884 13 5 0,000 0,02774594 0,09349684 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02774594 0,09336607 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02774594 0,09323567 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02774594 0,09310564 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02774594 0,09297596 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02774594 0,09284665 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02774594 0,0927177 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02774594 0,0925891 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02774594 0,09246086 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02774594 0,09233297 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02774594 0,09220544 ! basic amino acid transport GO:0015802 11 5 0,000 0,02774594 0,09207826 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02774594 0,09195143 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02774594 0,09182495 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02774594 0,09169882 ! depyrimidination GO:0045008 10 5 0,000 0,02774594 0,09157303 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02774594 0,09144759 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02774594 0,09132249 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02774594 0,09119773 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02774594 0,09107332 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02774594 0,09094924 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02774594 0,0908255 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02774594 0,09070209 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02774594 0,09057902 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02774594 0,09045629 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02774594 0,09033388 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02774594 0,09021181 ! response to arsenic GO:0046685 10 5 0,000 0,02774594 0,09009007 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02774594 0,08996865 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02774594 0,08984756 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02774594 0,0897268 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02774594 0,08960636 ! response to cadmium ion GO:0046686 7 5 0,000 0,02774594 0,08948625 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02774594 0,08936645 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02774594 0,08924698 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02774594 0,08912782 ! decidualization GO:0046697 11 5 0,000 0,02774594 0,08900899 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02774594 0,08889047 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02774594 0,08877226 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02774594 0,08865437 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02774594 0,08853679 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02774594 0,08841952 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02774594 0,08830257 ! neural tube patterning GO:0021532 7 5 0,000 0,02774594 0,08818592 ! embryonic cleavage GO:0040016 6 5 0,000 0,02774594 0,08806958 ! peroxisome fission GO:0016559 5 5 0,000 0,02774594 0,08795355 ! histone demethylation GO:0016577 10 5 0,000 0,02774594 0,08783782 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02774594 0,08772239 ! mitotic recombination GO:0006312 9 5 0,000 0,02774594 0,08760727 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02774594 0,08749245 ! metaphase plate congression GO:0051310 7 5 0,000 0,02774594 0,08737793 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02774594 0,08726371 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02774594 0,08714979 ! enteric nervous system development GO:0048484 8 5 0,000 0,02774594 0,08703617 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02774594 0,08692284 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02774594 0,08680981 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02774594 0,08669707 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02774594 0,08658462 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02774594 0,08647246 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02774594 0,0863606 ! plasminogen activation GO:0031639 5 5 0,000 0,02774594 0,08624902 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02774594 0,08613773 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02774594 0,08602673 ! metaphase GO:0051323 8 5 0,000 0,02774594 0,08591601 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02774594 0,08580558 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02774594 0,08569543 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02774594 0,08558557 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02774594 0,08547598 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02774594 0,08536668 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02774594 0,08525765 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02774594 0,0851489 ! response to redox state GO:0051775 5 5 0,000 0,02774594 0,08504043 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02774594 0,08493224 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02774594 0,08482432 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02774594 0,08471668 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02774594 0,0846093 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02774594 0,0845022 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02774594 0,08439537 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02774594 0,08428881 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02774594 0,08418252 ! striatum development GO:0021756 9 5 0,000 0,02774594 0,0840765 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02774594 0,08397074 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02774594 0,08386525 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02774594 0,08376003 ! glial cell migration GO:0008347 11 5 0,000 0,02774594 0,08365506 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02774594 0,08355036 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02774594 0,08344593 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02774594 0,08334175 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02774594 0,08323783 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02774594 0,08313417 ! neuroprotection GO:0043526 6 5 0,000 0,02774594 0,08303077 ! neural plate development GO:0001840 8 5 0,000 0,02774594 0,08292763 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02774594 0,08282474 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02774594 0,08272211 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02774594 0,08261973 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02774594 0,0825176 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02774594 0,08241573 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02774594 0,08231411 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02774594 0,08221273 ! spindle assembly GO:0051225 6 5 0,000 0,02774594 0,08211161 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02774594 0,08201074 GO:0016226|iron-sulfur cluster assembly, ! drug metabolic process GO:0017144 6 5 0,000 0,02774594 0,08191011 ! stem cell division GO:0017145 11 5 0,000 0,02774594 0,08180973 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02774594 0,0817096 ! organ regeneration GO:0031100 7 5 0,000 0,02774594 0,08160971 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02774594 0,08151006 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02774594 0,08141066 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02774594 0,0813115 ! endosome transport GO:0016197 108 47 1,000 0,02869048 0,08397726 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02869048 0,08387522 ! positive regulation of cyclase activity GO:0031281 103 47 1,000 0,02869048 0,08377343 ! JNK cascade GO:0007254 91 47 1,000 0,02869048 0,08367188 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,02869048 0,08357059 ! protein homooligomerization GO:0051260 76 47 1,000 0,02869048 0,08346953 ! cellular component disassembly GO:0022411 86 48 1,000 0,02982945 0,08667832 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02982945 0,08657376 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,02982945 0,08646946 ! positive regulation of lyase activity GO:0051349 104 48 1,000 0,02982945 0,0863654 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02982945 0,0862616 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,03098618 0,08949911 ! regulation of ion transport GO:0043269 77 49 1,000 0,03098618 0,08939179 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03098618 0,08928474 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,03216046 0,09255749 ! histone modification GO:0016570 91 50 1,000 0,03216046 0,09244691 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03216046 0,09233659 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0332026 0,09521509 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0332026 0,09510174 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0332026 0,09498866 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0332026 0,09487585 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0332026 0,0947633 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0332026 0,09465102 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0332026 0,09453901 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0332026 0,09442726 ! sleep GO:0030431 13 6 0,000 0,0332026 0,09431578 ! response to oxygen radical GO:0000305 11 6 0,000 0,0332026 0,09420456 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0332026 0,0940936 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0332026 0,0939829 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0332026 0,09387246 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0332026 0,09376228 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0332026 0,09365236 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0332026 0,0935427 ! forebrain regionalization GO:0021871 8 6 0,000 0,0332026 0,09343329 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0332026 0,09332414 ! male meiosis GO:0007140 7 6 0,000 0,0332026 0,09321524 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0332026 0,0931066 ! response to zinc ion GO:0010043 9 6 0,000 0,0332026 0,09299821 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0332026 0,09289007 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0332026 0,09278219 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0332026 0,09267455 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0332026 0,09256717 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0332026 0,09246003 ! malate metabolic process GO:0006108 11 6 0,000 0,0332026 0,09235314 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0332026 0,09224649 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0332026 0,0921401 ! protein refolding GO:0042026 15 6 0,000 0,0332026 0,09203394 ! opsonization GO:0008228 8 6 0,000 0,0332026 0,09192804 ! mating behavior GO:0007617 7 6 0,000 0,0332026 0,09182237 ! neuron remodeling GO:0016322 15 6 0,000 0,0332026 0,09171695 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0332026 0,09161177 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0332026 0,09150683 ! equilibrioception GO:0050957 14 6 0,000 0,0332026 0,09140213 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0332026 0,09129767 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0332026 0,09119345 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0332026 0,09108947 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0332026 0,09098572 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0332026 0,09088221 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0332026 0,09077894 ! toxin metabolic process GO:0009404 11 6 0,000 0,0332026 0,0906759 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0332026 0,09057309 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0332026 0,09047051 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0332026 0,09036817 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0332026 0,09026606 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0332026 0,09016418 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0332026 0,09006253 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0332026 0,08996111 ! thymic T cell selection GO:0045061 12 6 0,000 0,0332026 0,08985991 ! protein lipoylation GO:0009249 10 6 0,000 0,0332026 0,08975895 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0332026 0,08965821 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0332026 0,08955769 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0332026 0,08945741 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0332026 0,08935734 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0332026 0,0892575 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0332026 0,08915788 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0332026 0,08905849 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0332026 0,08895931 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0332026 0,08886036 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0332026 0,08876163 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0332026 0,08866311 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0332026 0,08856482 ! urea metabolic process GO:0019627 7 6 0,000 0,0332026 0,08846674 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0332026 0,08836888 ! neutrophil activation GO:0042119 8 6 0,000 0,0332026 0,08827123 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0332026 0,0881738 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0332026 0,08807659 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0332026 0,08797959 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0332026 0,0878828 ! neuron apoptosis GO:0051402 9 6 0,000 0,0332026 0,08778622 ! nucleoside salvage GO:0043174 9 6 0,000 0,0332026 0,08768986 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0332026 0,08759371 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0332026 0,08749777 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0332026 0,08740204 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0332026 0,08730652 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0332026 0,08721121 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0332026 0,0871161 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0332026 0,0870212 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0332026 0,08692651 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0332026 0,08683203 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0332026 0,08673775 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0332026 0,08664367 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0332026 0,0865498 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0332026 0,08645613 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0332026 0,08636266 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0332026 0,0862694 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0332026 0,08617634 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 11 6 0,000 0,0332026 0,08608347 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0332026 0,08599081 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0332026 0,08589835 ! interaction with symbiont GO:0051702 13 6 0,000 0,0332026 0,08580608 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0332026 0,08571402 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0332026 0,08562215 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0332026 0,08553048 ! response to copper ion GO:0046688 10 6 0,000 0,0332026 0,085439 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0332026 0,08534772 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0332026 0,08525663 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0332026 0,08516574 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0332026 0,08507504 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0332026 0,08498454 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0332026 0,08489422 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0332026 0,0848041 ! hair follicle maturation GO:0048820 7 6 0,000 0,0332026 0,08471417 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0332026 0,08462443 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0332026 0,08453488 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0332026 0,08444552 ! subpallium development GO:0021544 10 6 0,000 0,0332026 0,08435635 ! histone ubiquitination GO:0016574 8 6 0,000 0,0332026 0,08426737 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0332026 0,08417857 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0332026 0,08408996 ! G2 phase GO:0051319 16 6 0,000 0,0332026 0,08400154 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0332026 0,0839133 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0332026 0,08382525 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0332026 0,08373738 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0332026 0,0836497 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0332026 0,0835622 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0332026 0,08347488 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0332026 0,08338775 ! receptor internalization GO:0031623 10 6 0,000 0,0332026 0,0833008 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0332026 0,08321402 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0332026 0,08312743 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0332026 0,08304102 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0332026 0,08295479 ! protein deubiquitination GO:0016579 14 6 0,000 0,0332026 0,08286874 ! protein destabilization GO:0031648 9 6 0,000 0,0332026 0,08278286 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0332026 0,08269717 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0332026 0,08261165 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0332026 0,08252631 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0332026 0,08244114 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0332026 0,08235615 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0332026 0,08227133 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0332026 0,08218669 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0332026 0,08210222 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0332026 0,08201793 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0332026 0,08193381 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0332026 0,08184986 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0332026 0,08176608 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0332026 0,08168248 ! catecholamine transport GO:0051937 9 6 0,000 0,0332026 0,08159904 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0332026 0,08151578 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0332026 0,08143268 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0332026 0,08134976 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0332026 0,081267 ! maternal placenta development GO:0001893 12 6 0,000 0,0332026 0,08118441 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0332026 0,08110199 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,0332026 0,08101974 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0332026 0,08093765 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0332026 0,08085573 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0332026 0,08077398 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0332026 0,08069239 ! positive regulation of binding GO:0051099 78 51 1,000 0,03335204 0,08097378 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03335204 0,08089215 ! vesicle organization GO:0016050 107 51 1,000 0,03335204 0,08081069 ! regulation of cell shape GO:0008360 125 51 1,000 0,03335204 0,08072939 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03456071 0,08357092 ! synapse organization GO:0050808 85 52 1,000 0,03456071 0,08348702 ! cell maturation GO:0048469 100 53 1,000 0,03578623 0,08636075 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03702838 0,08926882 GO:0010863|positive regulation of phospholipase C activity, ! glucose catabolic process GO:0006007 82 55 1,000 0,03828694 0,09221058 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03828694 0,09211837 ! heart morphogenesis GO:0003007 97 55 1,000 0,03828694 0,09202634 ! nuclear export GO:0051168 97 55 1,000 0,03828694 0,0919345 ! tRNA transcription GO:0009304 14 7 0,000 0,03862882 0,09266295 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03862882 0,09257065 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03862882 0,09247854 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03862882 0,09238662 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03862882 0,09229487 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03862882 0,09220331 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03862882 0,09211193 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03862882 0,09202073 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03862882 0,09192971 ! prostate gland development GO:0030850 13 7 0,000 0,03862882 0,09183887 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03862882 0,09174821 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03862882 0,09165773 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03862882 0,09156743 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03862882 0,0914773 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03862882 0,09138735 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03862882 0,09129758 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03862882 0,09120799 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03862882 0,09111857 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03862882 0,09102932 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03862882 0,09094025 ! glycolipid transport GO:0046836 10 7 0,000 0,03862882 0,09085136 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03862882 0,09076263 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03862882 0,09067409 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03862882 0,09058571 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03862882 0,0904975 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03862882 0,09040947 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03862882 0,09032161 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03862882 0,09023392 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03862882 0,0901464 ! pericardium development GO:0060039 14 7 0,000 0,03862882 0,09005905 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03862882 0,08997187 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03862882 0,08988485 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03862882 0,08979801 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03862882 0,08971133 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03862882 0,08962482 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03862882 0,08953848 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03862882 0,0894523 ! rhythmic behavior GO:0007622 15 7 0,000 0,03862882 0,08936629 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03862882 0,08928044 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03862882 0,08919476 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03862882 0,08910924 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03862882 0,08902389 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03862882 0,0889387 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03862882 0,08885367 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03862882 0,0887688 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03862882 0,0886841 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03862882 0,08859956 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03862882 0,08851518 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03862882 0,08843096 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03862882 0,0883469 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03862882 0,088263 ! spinal cord patterning GO:0021511 13 7 0,000 0,03862882 0,08817926 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03862882 0,08809568 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03862882 0,08801225 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03862882 0,08792899 ! adrenal gland development GO:0030325 17 7 0,000 0,03862882 0,08784588 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03862882 0,08776292 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03862882 0,08768013 ! ovulation GO:0030728 9 7 0,000 0,03862882 0,08759749 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03862882 0,08751501 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03862882 0,08743268 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03862882 0,0873505 ! microtubule nucleation GO:0007020 20 7 0,000 0,03862882 0,08726849 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03862882 0,08718662 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03862882 0,08710491 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03862882 0,08702335 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03862882 0,08694194 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03862882 0,08686069 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03862882 0,08677959 ! galactose metabolic process GO:0006012 13 7 0,000 0,03862882 0,08669864 ! vesicle fusion GO:0006906 17 7 0,000 0,03862882 0,08661784 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03862882 0,08653719 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03862882 0,08645669 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03862882 0,08637634 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03862882 0,08629613 ! purine salvage GO:0043101 10 7 0,000 0,03862882 0,08621608 ! nucleoside transport GO:0015858 8 7 0,000 0,03862882 0,08613618 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03862882 0,08605642 ! parturition GO:0007567 14 7 0,000 0,03862882 0,08597682 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03862882 0,08589735 ! rRNA modification GO:0000154 14 7 0,000 0,03862882 0,08581804 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03862882 0,08573887 ! spindle checkpoint GO:0031577 15 7 0,000 0,03862882 0,08565985 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03862882 0,08558097 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03862882 0,08550224 ! macrophage differentiation GO:0030225 11 7 0,000 0,03862882 0,08542366 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03862882 0,08534521 ! centrosome duplication GO:0051298 13 7 0,000 0,03862882 0,08526691 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03862882 0,08518876 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03862882 0,08511075 ! eating behavior GO:0042755 7 7 0,000 0,03862882 0,08503288 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03862882 0,08495515 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03862882 0,08487757 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03862882 0,08480013 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03862882 0,08472282 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03862882 0,08464566 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03862882 0,08456864 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03862882 0,08449176 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03862882 0,08441502 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03862882 0,08433842 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03862882 0,08426196 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03862882 0,08418563 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03862882 0,08410945 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03862882 0,0840334 ! regulation of meiosis GO:0040020 12 7 0,000 0,03862882 0,08395749 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03862882 0,08388171 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03862882 0,08380607 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03862882 0,08373057 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03862882 0,08365521 ! transcription termination GO:0006353 13 7 0,000 0,03862882 0,08357998 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03862882 0,08350489 ! anaphase GO:0051322 17 7 0,000 0,03862882 0,08342993 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03862882 0,0833551 ! axonal fasciculation GO:0007413 18 7 0,000 0,03862882 0,08328041 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03862882 0,08320585 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03862882 0,08313143 ! diuresis GO:0030146 12 7 0,000 0,03862882 0,08305714 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03862882 0,08298298 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03862882 0,08290895 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03862882 0,08283506 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03862882 0,0827613 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03862882 0,08268767 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03862882 0,08261417 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03862882 0,0825408 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03862882 0,08246756 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03862882 0,08239445 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03862882 0,08232147 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03862882 0,08224862 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03862882 0,08217589 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,03862882 0,0821033 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03862882 0,08203084 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03862882 0,0819585 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03862882 0,08188629 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03862882 0,08181421 ! adult feeding behavior GO:0008343 9 7 0,000 0,03862882 0,08174225 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03862882 0,08167042 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03862882 0,08159872 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03862882 0,08152714 ! muscle adaptation GO:0043500 14 7 0,000 0,03862882 0,08145569 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03862882 0,08138436 ! retina homeostasis GO:0001895 12 7 0,000 0,03862882 0,08131316 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03862882 0,08124208 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03862882 0,08117112 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03862882 0,08110029 ! protein prenylation GO:0018342 18 7 0,000 0,03862882 0,08102959 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03862882 0,080959 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03862882 0,08088854 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03862882 0,08081821 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,03956168 0,082698 ! lipid modification GO:0030258 97 57 1,000 0,04085239 0,08532191 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04085239 0,08524791 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04215884 0,0878979 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04348084 0,09057566 ! DNA catabolic process GO:0006308 86 59 1,000 0,04348084 0,09049731 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04348084 0,09041909 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04402476 0,09147113 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04402476 0,09139221 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04402476 0,09131342 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04402476 0,09123477 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04402476 0,09115625 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04402476 0,09107787 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04402476 0,09099963 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04402476 0,09092152 ! meiotic prophase I GO:0007128 13 8 0,000 0,04402476 0,09084354 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04402476 0,0907657 ! oligopeptide transport GO:0006857 15 8 0,000 0,04402476 0,09068799 ! UTP metabolic process GO:0046051 8 8 0,000 0,04402476 0,09061041 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04402476 0,09053296 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04402476 0,09045565 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04402476 0,09037847 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04402476 0,09030142 ! succinate metabolic process GO:0006105 14 8 0,000 0,04402476 0,0902245 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04402476 0,09014772 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04402476 0,09007106 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04402476 0,08999453 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04402476 0,08991814 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04402476 0,08984187 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04402476 0,08976573 ! reflex GO:0060004 16 8 0,000 0,04402476 0,08968973 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04402476 0,08961385 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04402476 0,0895381 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04402476 0,08946247 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04402476 0,08938698 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04402476 0,08931161 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04402476 0,08923637 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04402476 0,08916125 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04402476 0,08908626 ! histidine metabolic process GO:0006547 16 8 0,000 0,04402476 0,0890114 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04402476 0,08893666 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04402476 0,08886205 ! glycine catabolic process GO:0006546 13 8 0,000 0,04402476 0,08878757 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04402476 0,08871321 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04402476 0,08863897 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04402476 0,08856486 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04402476 0,08849087 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04402476 0,088417 ! macrophage activation GO:0042116 12 8 0,000 0,04402476 0,08834326 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04402476 0,08826964 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04402476 0,08819614 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04402476 0,08812277 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04402476 0,08804952 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04402476 0,08797638 ! osteoblast development GO:0002076 16 8 0,000 0,04402476 0,08790338 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04402476 0,08783049 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04402476 0,08775772 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04402476 0,08768507 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04402476 0,08761255 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04402476 0,08754014 ! intermediate filament organization GO:0045109 12 8 0,000 0,04402476 0,08746785 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04402476 0,08739568 ! cellular extravasation GO:0045123 12 8 0,000 0,04402476 0,08732363 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04402476 0,0872517 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04402476 0,08717989 ! response to antibiotic GO:0046677 11 8 0,000 0,04402476 0,0871082 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04402476 0,08703662 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04402476 0,08696516 ! DNA topological change GO:0006265 12 8 0,000 0,04402476 0,08689382 ! response to tropane GO:0014073 15 8 0,000 0,04402476 0,0868226 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04402476 0,08675149 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04402476 0,0866805 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04402476 0,08660962 ! mast cell activation GO:0045576 14 8 0,000 0,04402476 0,08653886 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04402476 0,08646822 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04402476 0,08639769 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04402476 0,08632728 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04402476 0,08625698 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04402476 0,08618679 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04402476 0,08611672 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04402476 0,08604676 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04402476 0,08597692 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04402476 0,08590719 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04402476 0,08583757 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04402476 0,08576807 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04402476 0,08569868 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04402476 0,0856294 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04402476 0,08556023 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04402476 0,08549118 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04402476 0,08542223 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04402476 0,0853534 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04402476 0,08528468 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04402476 0,08521606 ! hormone catabolic process GO:0042447 17 8 0,000 0,04402476 0,08514756 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04402476 0,08507917 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04402476 0,08501089 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04402476 0,08494272 ! ATP catabolic process GO:0006200 11 8 0,000 0,04402476 0,08487465 ! blastocyst growth GO:0001832 19 8 0,000 0,04402476 0,0848067 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04402476 0,08473885 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04402476 0,08467112 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04402476 0,08460349 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04402476 0,08453597 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04402476 0,08446855 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04402476 0,08440125 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04402476 0,08433405 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04402476 0,08426696 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04402476 0,08419997 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04402476 0,0841331 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04402476 0,08406632 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04402476 0,08399966 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04402476 0,0839331 ! kidney development GO:0001822 122 60 1,000 0,04481815 0,08537804 ! viral reproductive process GO:0022415 126 62 1,000 0,0475379 0,09048749 ! gonad development GO:0008406 98 62 1,000 0,0475379 0,09041596 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,04891992 0,09297103 ! detection of external stimulus GO:0009581 91 63 1,000 0,04891992 0,09289765 ! axon extension GO:0048675 15 9 0,000 0,04939059 0,09371747 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04939059 0,09364362 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04939059 0,09356989 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04939059 0,09349627 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04939059 0,09342277 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04939059 0,09334938 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04939059 0,0932761 ! phosphate transport GO:0006817 19 9 0,000 0,04939059 0,09320295 ! reproductive behavior GO:0019098 19 9 0,000 0,04939059 0,0931299 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04939059 0,09305698 ! CTP metabolic process GO:0046036 9 9 0,000 0,04939059 0,09298416 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04939059 0,09291146 ! GTP metabolic process GO:0046039 9 9 0,000 0,04939059 0,09283887 ! RNA methylation GO:0001510 15 9 0,000 0,04939059 0,0927664 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04939059 0,09269404 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04939059 0,09262179 ! artery development GO:0060840 24 9 0,000 0,04939059 0,09254966 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04939059 0,09247763 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04939059 0,09240572 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04939059 0,09233392 ! chemosensory behavior GO:0007635 20 9 0,000 0,04939059 0,09226223 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04939059 0,09219066 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04939059 0,09211919 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04939059 0,09204784 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04939059 0,09197659 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04939059 0,09190546 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04939059 0,09183443 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04939059 0,09176352 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04939059 0,09169271 ! protein targeting to ER GO:0045047 22 9 0,000 0,04939059 0,09162202 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04939059 0,09155143 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04939059 0,09148095 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04939059 0,09141058 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04939059 0,09134032 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04939059 0,09127017 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04939059 0,09120012 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04939059 0,09113018 ! mannose metabolic process GO:0006013 13 9 0,000 0,04939059 0,09106035 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04939059 0,09099063 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04939059 0,09092101 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04939059 0,0908515 ! receptor clustering GO:0043113 18 9 0,000 0,04939059 0,09078209 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04939059 0,09071279 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04939059 0,0906436 ! ruffle organization GO:0031529 15 9 0,000 0,04939059 0,09057451 ! retinol metabolic process GO:0042572 18 9 0,000 0,04939059 0,09050553 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04939059 0,09043665 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04939059 0,09036788 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04939059 0,09029921 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04939059 0,09023064 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04939059 0,09016218 ! segment specification GO:0007379 13 9 0,000 0,04939059 0,09009383 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04939059 0,09002557 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04939059 0,08995742 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04939059 0,08988938 ! response to amine stimulus GO:0014075 13 9 0,000 0,04939059 0,08982143 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04939059 0,08975359 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04939059 0,08968585 ! erythrocyte development GO:0048821 15 9 0,000 0,04939059 0,08961822 ! gas homeostasis GO:0033483 16 9 0,000 0,04939059 0,08955068 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04939059 0,08948325 ! renal water homeostasis GO:0003091 14 9 0,000 0,04939059 0,08941592 ! postreplication repair GO:0006301 22 9 0,000 0,04939059 0,08934869 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04939059 0,08928156 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04939059 0,08921453 ! icosanoid secretion GO:0032309 15 9 0,000 0,04939059 0,0891476 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04939059 0,08908078 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04939059 0,08901405 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04939059 0,08894742 ! regulation of cell division GO:0051302 15 9 0,000 0,04939059 0,0888809 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04939059 0,08881447 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04939059 0,08874814 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04939059 0,08868191 ! sterol catabolic process GO:0016127 11 9 0,000 0,04939059 0,08861578 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04939059 0,08854974 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04939059 0,08848381 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04939059 0,08841797 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04939059 0,08835224 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04939059 0,0882866 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04939059 0,08822105 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04939059 0,08815561 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04939059 0,08809026 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04939059 0,08802501 ! purine base metabolic process GO:0006144 21 9 0,000 0,04939059 0,08795985 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04939059 0,08789479 ! pigment granule transport GO:0051904 17 9 0,000 0,04939059 0,08782983 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04939059 0,08776496 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04939059 0,08770019 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04939059 0,08763551 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04939059 0,08757093 ! mitochondrion localization GO:0051646 15 9 0,000 0,04939059 0,08750645 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,05031642 0,08908117 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,05172721 0,09151152 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,05172721 0,09144428 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,05172721 0,09137714 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05315208 0,09382532 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,05315208 0,09375653 ! secondary metabolic process GO:0019748 116 66 1,000 0,05315208 0,09368784 ! developmental maturation GO:0021700 116 66 1,000 0,05315208 0,09361926 ! cell projection assembly GO:0030031 120 66 1,000 0,05315208 0,09355077 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,05459083 0,09601282 ! hexose catabolic process GO:0019320 104 67 1,000 0,05459083 0,09594269 ! adaptive immune response GO:0002250 119 67 1,000 0,05459083 0,09587266 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! chromosome segregation GO:0007059 113 67 1,000 0,05459083 0,09580273 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05472648 0,09597078 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05472648 0,09590088 ! synapsis GO:0007129 13 10 0,000 0,05472648 0,09583108 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05472648 0,09576139 ! N-glycan processing GO:0006491 20 10 0,000 0,05472648 0,09569179 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05472648 0,0956223 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05472648 0,09555291 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05472648 0,09548362 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05472648 0,09541443 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05472648 0,09534534 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05472648 0,09527635 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05472648 0,09520745 ! androgen metabolic process GO:0008209 17 10 0,000 0,05472648 0,09513866 ! phospholipid efflux GO:0033700 16 10 0,000 0,05472648 0,09506997 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05472648 0,09500138 ! pathogenesis GO:0009405 13 10 0,000 0,05472648 0,09493288 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05472648 0,09486449 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05472648 0,09479619 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05472648 0,09472799 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05472648 0,09465989 ! endoderm development GO:0007492 16 10 0,000 0,05472648 0,09459189 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05472648 0,09452398 ! arginine catabolic process GO:0006527 13 10 0,000 0,05472648 0,09445618 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05472648 0,09438847 ! proline metabolic process GO:0006560 13 10 0,000 0,05472648 0,09432085 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05472648 0,09425334 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05472648 0,09418592 ! V(D)J recombination GO:0033151 28 10 0,000 0,05472648 0,09411859 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05472648 0,09405136 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05472648 0,09398423 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05472648 0,0939172 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05472648 0,09385026 ! multicellular organism growth GO:0035264 18 10 0,000 0,05472648 0,09378341 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05472648 0,09371666 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05472648 0,09365001 ! epithelial cell development GO:0002064 20 10 0,000 0,05472648 0,09358345 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05472648 0,09351698 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05472648 0,09345061 ! macroautophagy GO:0016236 17 10 0,000 0,05472648 0,09338433 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05472648 0,09331815 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05472648 0,09325206 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05472648 0,09318606 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05472648 0,09312016 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05472648 0,09305435 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05472648 0,09298864 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05472648 0,09292301 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05472648 0,09285748 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05472648 0,09279204 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05472648 0,0927267 ! response to dsRNA GO:0043331 20 10 0,000 0,05472648 0,09266144 ! DNA ligation GO:0006266 19 10 0,000 0,05472648 0,09259628 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05472648 0,09253121 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05472648 0,09246623 ! melanosome localization GO:0032400 16 10 0,000 0,05472648 0,09240134 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05472648 0,09233654 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05472648 0,09227184 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05472648 0,09220722 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05472648 0,09214269 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05472648 0,09207826 ! mRNA cleavage GO:0006379 17 10 0,000 0,05472648 0,09201391 ! protein sumoylation GO:0016925 15 10 0,000 0,05472648 0,09194966 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05472648 0,09188549 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05472648 0,09182142 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05472648 0,09175743 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05472648 0,09169353 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05472648 0,09162972 ! salivary gland development GO:0007431 27 10 0,000 0,05472648 0,091566 ! prophase GO:0051324 15 10 0,000 0,05472648 0,09150237 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05472648 0,09143883 ! apical protein localization GO:0045176 15 10 0,000 0,05472648 0,09137537 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05472648 0,091312 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05472648 0,09124872 ! midbrain development GO:0030901 13 10 0,000 0,05472648 0,09118553 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05472648 0,09112243 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05472648 0,09105941 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05472648 0,09099648 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05472648 0,09093364 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05472648 0,09087088 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05472648 0,09080821 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05472648 0,09074563 ! detection of calcium ion GO:0005513 23 10 0,000 0,05472648 0,09068313 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05472648 0,09062072 ! blastocyst formation GO:0001825 17 10 0,000 0,05472648 0,0905584 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05472648 0,09049616 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05472648 0,090434 ! activation of innate immune response GO:0002218 12 10 0,000 0,05472648 0,09037194 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05472648 0,09030995 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05472648 0,09024805 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05472648 0,09018624 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05472648 0,09012451 ! viral reproduction GO:0016032 134 68 1,000 0,05604327 0,09222989 ! regulation of lipase activity GO:0060191 130 68 1,000 0,05604327 0,09216685 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,05750918 0,09451304 ! urogenital system development GO:0001655 137 69 1,000 0,05750918 0,09444853 ! appendage morphogenesis GO:0035107 135 70 1,000 0,05898839 0,09681178 GO:0035108|limb morphogenesis, ! respiratory burst GO:0045730 17 11 0,000 0,0600326 0,09845837 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0600326 0,0983913 ! neuron fate specification GO:0048665 17 11 0,000 0,0600326 0,09832432 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0600326 0,09825743 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0600326 0,09819063 ! thyroid gland development GO:0030878 26 11 0,000 0,0600326 0,09812393 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0600326 0,09805731 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0600326 0,09799079 ! response to pain GO:0048265 24 11 0,000 0,0600326 0,09792436 ! T cell proliferation GO:0042098 26 11 0,000 0,0600326 0,09785801 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0600326 0,09779176 GO:0010812|negative regulation of cell-substrate adhesion, ! ventral spinal cord development GO:0021517 21 11 0,000 0,0600326 0,09772559 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0600326 0,09765952 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0600326 0,09759353 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0600326 0,09752763 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0600326 0,09746182 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0600326 0,09739611 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0600326 0,09733047 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0600326 0,09726493 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0600326 0,09719948 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0600326 0,09713411 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0600326 0,09706883 ! UV protection GO:0009650 19 11 0,000 0,0600326 0,09700364 ! adult heart development GO:0007512 14 11 0,000 0,0600326 0,09693854 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0600326 0,09687352 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0600326 0,0968086 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0600326 0,09674375 ! regulation of organ growth GO:0046620 13 11 0,000 0,0600326 0,096679 ! pigment granule localization GO:0051875 20 11 0,000 0,0600326 0,09661433 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0600326 0,09654975 ! vasoconstriction GO:0042310 18 11 0,000 0,0600326 0,09648525 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0600326 0,09642084 ! embryonic axis specification GO:0000578 18 11 0,000 0,0600326 0,09635652 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0600326 0,09629228 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0600326 0,09622813 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0600326 0,09616406 ! DNA methylation GO:0006306 19 11 0,000 0,0600326 0,09610008 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0600326 0,09603619 ! zymogen activation GO:0031638 15 11 0,000 0,0600326 0,09597237 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0600326 0,09590865 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0600326 0,09584501 ! nucleosome positioning GO:0016584 15 11 0,000 0,0600326 0,09578145 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0600326 0,09571797 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0600326 0,09565459 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0600326 0,09559128 ! acid secretion GO:0046717 18 11 0,000 0,0600326 0,09552806 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0600326 0,09546492 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0600326 0,09540187 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0600326 0,09533889 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0600326 0,09527601 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0600326 0,0952132 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,0600326 0,09515048 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0600326 0,09508784 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0600326 0,09502528 ! germ cell migration GO:0008354 25 11 0,000 0,0600326 0,0949628 ! embryonic gut development GO:0048566 15 11 0,000 0,0600326 0,09490041 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0600326 0,0948381 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0600326 0,09477587 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0600326 0,09471372 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0600326 0,09465165 ! defense response to fungus GO:0050832 13 11 0,000 0,0600326 0,09458967 ! developmental induction GO:0031128 19 11 0,000 0,0600326 0,09452776 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0600326 0,09446594 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0600326 0,0944042 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0600326 0,09434254 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0600326 0,09428096 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0600326 0,09421945 ! nucleus localization GO:0051647 19 11 0,000 0,0600326 0,09415803 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0600326 0,09409669 ! reproductive structure development GO:0048608 113 71 1,000 0,0604807 0,09473735 ! appendage development GO:0048736 136 71 1,000 0,0604807 0,09467571 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,0604807 0,09461415 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06198591 0,09690585 ! carbohydrate transport GO:0008643 110 72 1,000 0,06198591 0,09684293 ! axon guidance GO:0007411 139 73 1,000 0,06350384 0,09915006 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,0650343 0,10147375 GO:0090046|regulation of transcription regulator activity, ! organelle localization GO:0051640 136 74 1,000 0,0650343 0,10140798 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0653091 0,10177053 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0653091 0,10170466 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0653091 0,10163887 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0653091 0,10157317 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0653091 0,10150756 ! cartilage condensation GO:0001502 20 12 0,000 0,0653091 0,10144203 ! mating GO:0007618 17 12 0,000 0,0653091 0,10137658 ! protein complex disassembly GO:0043241 27 12 0,000 0,0653091 0,10131122 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0653091 0,10124594 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0653091 0,10118075 ! hippocampus development GO:0021766 26 12 0,000 0,0653091 0,10111564 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0653091 0,10105061 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0653091 0,10098567 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0653091 0,10092081 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0653091 0,10085603 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0653091 0,10079134 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0653091 0,10072673 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0653091 0,1006622 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0653091 0,10059776 ! drug transport GO:0015893 16 12 0,000 0,0653091 0,1005334 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0653091 0,10046912 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0653091 0,10040492 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0653091 0,1003408 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0653091 0,10027677 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0653091 0,10021282 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0653091 0,10014895 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0653091 0,10008516 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0653091 0,10002145 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0653091 0,09995782 ! entry into host cell GO:0030260 32 12 0,000 0,0653091 0,09989428 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,0653091 0,09983081 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0653091 0,09976743 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0653091 0,09970412 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0653091 0,0996409 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0653091 0,09957776 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0653091 0,09951469 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0653091 0,09945171 ! protein homotetramerization GO:0051289 21 12 0,000 0,0653091 0,0993888 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0653091 0,09932598 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0653091 0,09926323 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0653091 0,09920057 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0653091 0,09913798 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0653091 0,09907547 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0653091 0,09901304 ! cranial nerve development GO:0021545 20 12 0,000 0,0653091 0,09895069 ! fucose catabolic process GO:0019317 22 12 0,000 0,0653091 0,09888842 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0653091 0,09882622 ! histone methylation GO:0016571 26 12 0,000 0,0653091 0,09876411 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0653091 0,09870207 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0653091 0,09864011 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0653091 0,09857823 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0653091 0,09851642 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0653091 0,0984547 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0653091 0,09839305 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0653091 0,09833148 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0653091 0,09826998 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0653091 0,09820856 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0653091 0,09814722 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0653091 0,09808595 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,06657709 0,09992794 ! rhythmic process GO:0048511 128 75 1,000 0,06657709 0,09986564 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,06813205 0,1021344 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,06813205 0,1020708 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,06813205 0,10200729 ! regulation of catabolic process GO:0009894 161 76 1,000 0,06813205 0,10194385 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,06969898 0,10422358 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07055616 0,10543983 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07055616 0,10537438 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07055616 0,10530901 ! peroxisomal transport GO:0043574 24 13 0,000 0,07055616 0,10524372 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07055616 0,10517852 ! lipid localization GO:0010876 28 13 0,000 0,07055616 0,10511339 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07055616 0,10504835 ! organelle fusion GO:0048284 32 13 0,000 0,07055616 0,10498338 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07055616 0,1049185 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07055616 0,10485369 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07055616 0,10478897 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07055616 0,10472432 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07055616 0,10465976 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07055616 0,10459527 ! methionine metabolic process GO:0006555 27 13 0,000 0,07055616 0,10453087 ! plasma membrane organization GO:0007009 24 13 0,000 0,07055616 0,10446654 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07055616 0,10440229 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07055616 0,10433812 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07055616 0,10427403 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07055616 0,10421002 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07055616 0,10414609 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07055616 0,10408224 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07055616 0,10401846 ! exocrine system development GO:0035272 32 13 0,000 0,07055616 0,10395476 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07055616 0,10389114 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07055616 0,1038276 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07055616 0,10376414 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07055616 0,10370075 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07055616 0,10363744 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07055616 0,10357421 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07055616 0,10351105 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07055616 0,10344797 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07055616 0,10338497 ! ribosome assembly GO:0042255 17 13 0,000 0,07055616 0,10332205 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07055616 0,1032592 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07055616 0,10319643 ! chromatin silencing GO:0006342 26 13 0,000 0,07055616 0,10313373 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07055616 0,10307111 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07055616 0,10300857 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07055616 0,1029461 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07055616 0,10288371 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07055616 0,1028214 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07055616 0,10275916 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07055616 0,10269699 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07055616 0,1026349 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07055616 0,10257289 ! embryonic placenta development GO:0001892 23 13 0,000 0,07055616 0,10251095 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07055616 0,10244908 ! insulin secretion GO:0030073 23 13 0,000 0,07055616 0,10238729 ! actin filament polymerization GO:0030041 24 13 0,000 0,07055616 0,10232557 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07055616 0,10226393 ! acrosome reaction GO:0007340 18 13 0,000 0,07055616 0,10220236 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,0712777 0,1031854 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,07446979 0,10774162 ! response to metal ion GO:0010038 140 80 1,000 0,07446979 0,10767687 ! protein import into nucleus GO:0006606 158 80 1,000 0,07446979 0,1076122 ! rRNA transcription GO:0009303 25 14 0,000 0,07577394 0,10943103 ! lactation GO:0007595 26 14 0,000 0,07577394 0,10936539 ! reproductive cellular process GO:0048610 20 14 0,000 0,07577394 0,10929982 ! tRNA modification GO:0006400 20 14 0,000 0,07577394 0,10923433 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07577394 0,10916892 ! regulation of S phase GO:0033261 23 14 0,000 0,07577394 0,10910359 ! water transport GO:0006833 21 14 0,000 0,07577394 0,10903834 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07577394 0,10897316 ! non-recombinational repair GO:0000726 25 14 0,000 0,07577394 0,10890807 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07577394 0,10884305 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07577394 0,1087781 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07577394 0,10871324 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07577394 0,10864845 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07577394 0,10858374 ! palate development GO:0060021 31 14 0,000 0,07577394 0,10851911 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07577394 0,10845455 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07577394 0,10839007 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07577394 0,10832567 ! arginine metabolic process GO:0006525 17 14 0,000 0,07577394 0,10826134 ! regulation of heart rate GO:0002027 24 14 0,000 0,07577394 0,10819709 ! organic alcohol transport GO:0015850 29 14 0,000 0,07577394 0,10813292 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07577394 0,10806882 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07577394 0,1080048 ! embryo implantation GO:0007566 30 14 0,000 0,07577394 0,10794085 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07577394 0,10787698 ! L-amino acid transport GO:0015807 30 14 0,000 0,07577394 0,10781319 ! bone mineralization GO:0030282 17 14 0,000 0,07577394 0,10774947 ! stem cell development GO:0048864 43 14 0,000 0,07577394 0,10768582 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07577394 0,10762226 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07577394 0,10755876 ! cerebellum development GO:0021549 21 14 0,000 0,07577394 0,10749534 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07577394 0,107432 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07577394 0,10736873 ! cofactor transport GO:0051181 26 14 0,000 0,07577394 0,10730553 ! NADP metabolic process GO:0006739 24 14 0,000 0,07577394 0,10724241 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07577394 0,10717937 ! intestinal absorption GO:0050892 25 14 0,000 0,07577394 0,10711639 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07577394 0,10705349 ! oxygen transport GO:0015671 21 14 0,000 0,07577394 0,10699067 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07577394 0,10692792 ! male genitalia development GO:0030539 24 14 0,000 0,07577394 0,10686524 ! regulation of axon extension GO:0030516 37 14 0,000 0,07577394 0,10680264 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07577394 0,10674011 ! nuclear import GO:0051170 161 81 1,000 0,07608281 0,10711249 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,07770692 0,109335 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,07770692 0,1092711 ! regulation of lyase activity GO:0051339 160 83 1,000 0,07934193 0,11150507 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0809626 0,1137163 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0809626 0,11364995 ! superoxide anion generation GO:0042554 20 15 0,000 0,0809626 0,11358368 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0809626 0,11351749 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0809626 0,11345138 ! copper ion transport GO:0006825 20 15 0,000 0,0809626 0,11338534 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0809626 0,11331938 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0809626 0,1132535 ! sulfate transport GO:0008272 23 15 0,000 0,0809626 0,11318769 ! response to cAMP GO:0051591 22 15 0,000 0,0809626 0,11312196 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0809626 0,11305631 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0809626 0,11299073 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0809626 0,11292523 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0809626 0,1128598 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0809626 0,11279445 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0809626 0,11272918 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0809626 0,11266398 ! vesicle coating GO:0006901 33 15 0,000 0,0809626 0,11259885 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0809626 0,1125338 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0809626 0,11246883 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0809626 0,11240393 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0809626 0,11233911 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0809626 0,11227436 ! histone deacetylation GO:0016575 20 15 0,000 0,0809626 0,11220969 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0809626 0,11214509 ! tissue regeneration GO:0042246 26 15 0,000 0,0809626 0,11208056 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0809626 0,11201611 ! water homeostasis GO:0030104 27 15 0,000 0,0809626 0,11195173 ! muscle maintenance GO:0046716 26 15 0,000 0,0809626 0,11188743 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0809626 0,1118232 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0809626 0,11175904 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0809626 0,11169496 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0809626 0,11163095 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0809626 0,11156702 ! cell killing GO:0001906 29 15 0,000 0,0809626 0,11150316 ! detection of bacterium GO:0016045 18 15 0,000 0,0809626 0,11143937 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0809626 0,11137565 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0809626 0,11131201 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0809626 0,11124844 ! peptide hormone processing GO:0016486 23 15 0,000 0,0809626 0,11118494 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,08098768 0,11115594 ! nucleosome assembly GO:0006334 122 85 1,000 0,082644 0,11336457 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,082644 0,11329998 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,08431071 0,11551912 ! chromatin assembly GO:0031497 124 86 1,000 0,08431071 0,11545338 ! alcohol catabolic process GO:0046164 130 86 1,000 0,08431071 0,1153877 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,08598766 0,11761587 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,08598766 0,11754904 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0861223 0,11766624 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0861223 0,11759946 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0861223 0,11753276 ! filopodium assembly GO:0046847 32 16 0,000 0,0861223 0,11746613 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0861223 0,11739958 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0861223 0,1173331 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0861223 0,1172667 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0861223 0,11720037 ! startle response GO:0001964 28 16 0,000 0,0861223 0,11713412 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0861223 0,11706794 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0861223 0,11700184 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0861223 0,11693581 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0861223 0,11686986 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0861223 0,11680398 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0861223 0,11673817 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0861223 0,11667244 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0861223 0,11660678 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0861223 0,1165412 GO:0031114|regulation of microtubule depolymerization, ! fructose metabolic process GO:0006000 25 16 0,000 0,0861223 0,11647569 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0861223 0,11641026 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0861223 0,11634489 ! intermediate filament-based process GO:0045103 32 16 0,000 0,0861223 0,1162796 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0861223 0,11621439 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0861223 0,11614925 ! axon cargo transport GO:0008088 43 16 0,000 0,0861223 0,11608418 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0861223 0,11601918 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0861223 0,11595426 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,0861223 0,1158894 ! DNA replication initiation GO:0006270 27 16 0,000 0,0861223 0,11582463 ! neuron recognition GO:0008038 35 16 0,000 0,0861223 0,11575992 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0861223 0,11569528 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0861223 0,11563072 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0861223 0,11556623 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0861223 0,11550181 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0861223 0,11543747 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0861223 0,11537319 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0861223 0,11530899 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0861223 0,11524486 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0861223 0,1151808 ! regulation of neurological system process GO:0031644 148 88 1,000 0,08767467 0,11719181 ! regulation of DNA binding GO:0051101 155 88 1,000 0,08767467 0,11712674 ! ossification GO:0001503 188 90 1,000 0,09107824 0,12160613 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,09107824 0,12153868 ! sex differentiation GO:0007548 145 90 1,000 0,09107824 0,12147131 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,09107824 0,12140401 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0912532 0,12156988 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0912532 0,12150261 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0912532 0,1214354 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0912532 0,12136828 ! signal complex assembly GO:0007172 41 17 0,000 0,0912532 0,12130122 ! endothelial cell migration GO:0043542 28 17 0,000 0,0912532 0,12123424 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0912532 0,12116733 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0912532 0,1211005 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0912532 0,12103374 ! adult walking behavior GO:0007628 33 17 0,000 0,0912532 0,12096706 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0912532 0,12090045 ! heart looping GO:0001947 30 17 0,000 0,0912532 0,12083391 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0912532 0,12076744 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0912532 0,12070105 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0912532 0,12063473 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0912532 0,12056848 ! glycine metabolic process GO:0006544 28 17 0,000 0,0912532 0,12050231 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0912532 0,12043621 ! NAD metabolic process GO:0019674 29 17 0,000 0,0912532 0,12037018 ! membrane budding GO:0006900 37 17 0,000 0,0912532 0,12030422 ! DNA integration GO:0015074 29 17 0,000 0,0912532 0,12023834 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0912532 0,12017253 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0912532 0,12010679 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0912532 0,12004112 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0912532 0,11997552 ! genitalia development GO:0048806 30 17 0,000 0,0912532 0,11991 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0912532 0,11984455 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0912532 0,11977917 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0912532 0,11971385 ! steroid catabolic process GO:0006706 31 17 0,000 0,0912532 0,11964862 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0912532 0,11958345 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0912532 0,11951835 ! gas transport GO:0015669 25 17 0,000 0,0912532 0,11945332 ! organic cation transport GO:0015695 31 17 0,000 0,0912532 0,11938837 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0912532 0,11932348 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0912532 0,11925867 ! microspike assembly GO:0030035 36 17 0,000 0,0912532 0,11919392 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0912532 0,11912925 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0912532 0,11906465 ! bone development GO:0060348 189 91 1,000 0,09279447 0,12101002 ! sterol metabolic process GO:0016125 152 91 1,000 0,09279447 0,12094447 ! response to protein stimulus GO:0051789 149 91 1,000 0,09279447 0,12087898 ! nucleosome organization GO:0034728 138 92 1,000 0,09452011 0,12306028 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,09625502 0,12525126 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09635547 0,1253142 ! neuron maturation GO:0042551 42 18 0,000 0,09635547 0,12524649 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09635547 0,12517887 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09635547 0,12511131 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09635547 0,12504383 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09635547 0,12497642 ! memory GO:0007613 31 18 0,000 0,09635547 0,12490909 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09635547 0,12484182 GO:0050886|endocrine process, ! patterning of blood vessels GO:0001569 39 18 0,000 0,09635547 0,12477463 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09635547 0,12470751 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09635547 0,12464046 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09635547 0,12457349 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09635547 0,12450659 ! response to retinoic acid GO:0032526 26 18 0,000 0,09635547 0,12443975 ! response to fungus GO:0009620 21 18 0,000 0,09635547 0,12437299 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09635547 0,12430631 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09635547 0,12423969 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09635547 0,12417315 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09635547 0,12410667 ! vitamin transport GO:0051180 27 18 0,000 0,09635547 0,12404027 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09635547 0,12397394 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09635547 0,12390768 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09635547 0,12384149 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09635547 0,12377537 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09635547 0,12370932 ! nerve development GO:0021675 28 18 0,000 0,09635547 0,12364334 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09635547 0,12357743 ! female pregnancy GO:0007565 164 94 1,000 0,09799903 0,12561836 ! transcription initiation GO:0006352 153 94 1,000 0,09799903 0,12555147 ! regulation of T cell activation GO:0050863 158 94 1,000 0,09799903 0,12548465 ! protein secretion GO:0009306 39 19 0,000 0,10142926 0,12980787 ! positive regulation of translation GO:0045727 30 19 0,000 0,10142926 0,12973886 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10142926 0,12966992 ! skin development GO:0043588 36 19 0,000 0,10142926 0,12960106 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10142926 0,12953227 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10142926 0,12946355 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10142926 0,12939491 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10142926 0,12932633 ! pigmentation during development GO:0048066 41 19 0,000 0,10142926 0,12925784 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10142926 0,12918941 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10142926 0,12912106 ! heme metabolic process GO:0042168 36 19 0,000 0,10142926 0,12905277 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10142926 0,12898456 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10142926 0,12891643 ! peptide cross-linking GO:0018149 37 19 0,000 0,10142926 0,12884836 ! protein export from nucleus GO:0006611 36 19 0,000 0,10142926 0,12878037 ! heart process GO:0003015 30 19 0,000 0,10142926 0,12871244 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10142926 0,12864459 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10142926 0,12857681 ! visual learning GO:0008542 36 19 0,000 0,10142926 0,12850911 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10142926 0,12844147 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10142926 0,12837391 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10142926 0,12830641 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10142926 0,12823899 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10142926 0,12817164 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10142926 0,12810435 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10142926 0,12803714 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10142926 0,12797 ! cilium assembly GO:0042384 37 19 0,000 0,10142926 0,12790293 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10142926 0,12783593 ! detection of stimulus GO:0051606 151 96 1,000 0,10151373 0,12787541 ! response to virus GO:0009615 160 98 1,000 0,10506301 0,13227713 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10647472 0,13398441 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10647472 0,13391437 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10647472 0,1338444 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10647472 0,13377451 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,10647472 0,13370469 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10647472 0,13363494 ! response to vitamin GO:0033273 31 20 0,000 0,10647472 0,13356527 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10647472 0,13349567 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10647472 0,13342614 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10647472 0,13335668 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10647472 0,1332873 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10647472 0,13321799 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10647472 0,13314875 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10647472 0,13307958 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10647472 0,13301048 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10647472 0,13294146 ! body fluid secretion GO:0007589 31 20 0,000 0,10647472 0,1328725 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10647472 0,13280362 ! peptide secretion GO:0002790 35 20 0,000 0,10647472 0,13273481 ! stem cell differentiation GO:0048863 53 20 0,000 0,10647472 0,13266607 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10647472 0,13259741 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10647472 0,13252881 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10647472 0,13246028 ! sensory perception of pain GO:0019233 30 20 0,000 0,10647472 0,13239183 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10647472 0,13232344 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10647472 0,13225513 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10647472 0,13218689 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10647472 0,13211871 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10647472 0,13205061 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10647472 0,13198258 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10647472 0,13191462 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10647472 0,13184673 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10647472 0,1317789 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10647472 0,13171115 ! actin filament-based movement GO:0030048 43 20 0,000 0,10647472 0,13164347 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10647472 0,13157585 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10647472 0,13150831 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,10685023 0,13190439 ! regulation of cell killing GO:0031341 42 21 0,000 0,11149203 0,13756401 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11149203 0,1374935 ! hormone secretion GO:0046879 38 21 0,000 0,11149203 0,13742306 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11149203 0,1373527 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11149203 0,1372824 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11149203 0,13721218 ! axis specification GO:0009798 38 21 0,000 0,11149203 0,13714203 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11149203 0,13707196 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11149203 0,13700195 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11149203 0,13693202 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11149203 0,13686215 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11149203 0,13679236 ! cytolysis GO:0019835 24 21 0,000 0,11149203 0,13672264 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11149203 0,13665299 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11149203 0,13658341 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11149203 0,1365139 ! DNA modification GO:0006304 34 21 0,000 0,11149203 0,13644446 ! collagen fibril organization GO:0030199 59 21 0,000 0,11149203 0,1363751 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11149203 0,1363058 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11149203 0,13623658 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11149203 0,13616742 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11149203 0,13609833 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11149203 0,13602932 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11149203 0,13596037 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11149203 0,1358915 ! collagen catabolic process GO:0030574 28 21 0,000 0,11149203 0,13582269 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11149203 0,13575396 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,11648132 0,14175724 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11648132 0,14168557 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11648132 0,14161398 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11648132 0,14154246 ! microtubule-based transport GO:0010970 54 22 0,000 0,11648132 0,14147101 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11648132 0,14139963 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11648132 0,14132832 ! keratinization GO:0031424 28 22 0,000 0,11648132 0,14125709 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11648132 0,14118593 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11648132 0,14111484 ! sensory perception of taste GO:0050909 28 22 0,000 0,11648132 0,14104382 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11648132 0,14097287 ! lysosome organization GO:0007040 41 22 0,000 0,11648132 0,14090199 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11648132 0,14083119 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11648132 0,14076045 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11648132 0,14068979 ! fucose metabolic process GO:0006004 39 22 0,000 0,11648132 0,1406192 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11648132 0,14054868 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11648132 0,14047823 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11648132 0,14040785 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,11648132 0,14033754 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11648132 0,1402673 ! sarcomere organization GO:0045214 30 22 0,000 0,11648132 0,14019713 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11648132 0,14012703 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11648132 0,140057 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11648132 0,13998704 ! protein stabilization GO:0050821 39 22 0,000 0,11648132 0,13991716 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12144277 0,14580404 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12144277 0,14573132 ! gluconeogenesis GO:0006094 33 23 0,000 0,12144277 0,14565867 ! viral genome replication GO:0019079 41 23 0,000 0,12144277 0,1455861 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12144277 0,14551359 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12144277 0,14544116 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12144277 0,14536881 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12144277 0,14529652 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12144277 0,1452243 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12144277 0,14515216 ! visual behavior GO:0007632 42 23 0,000 0,12144277 0,14508009 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12144277 0,14500809 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12144277 0,14493616 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,12144277 0,1448643 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12144277 0,14479252 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12144277 0,1447208 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12144277 0,14464916 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12144277 0,14457758 GO:0051693|actin filament capping, ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12144277 0,14450608 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12144277 0,14443465 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12144277 0,14436329 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12144277 0,144292 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12144277 0,14422078 ! hormone transport GO:0009914 40 23 0,000 0,12144277 0,14414963 ! cell-cell recognition GO:0009988 25 23 0,000 0,12144277 0,14407855 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12144277 0,14400754 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12144277 0,1439366 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,12144277 0,14386573 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12144277 0,14379493 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12144277 0,1437242 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12637651 0,14948962 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12637651 0,14941616 ! vesicle docking GO:0048278 47 24 0,000 0,12637651 0,14934278 ! spinal cord development GO:0021510 47 24 0,000 0,12637651 0,14926946 ! vacuole organization GO:0007033 43 24 0,000 0,12637651 0,14919622 ! digestive system process GO:0022600 39 24 0,000 0,12637651 0,14912305 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12637651 0,14904995 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,12637651 0,14897692 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12637651 0,14890396 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12637651 0,14883108 ! membrane depolarization GO:0051899 39 24 0,000 0,12637651 0,14875826 ! pentose metabolic process GO:0019321 35 24 0,000 0,12637651 0,14868552 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12637651 0,14861285 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12637651 0,14854025 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12637651 0,14846772 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12637651 0,14839526 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12637651 0,14832287 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12637651 0,14825056 ! regulation of amine transport GO:0051952 40 24 0,000 0,12637651 0,14817831 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13128272 0,15385593 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13128272 0,15378102 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13128272 0,15370619 ! phototransduction GO:0007602 33 25 0,000 0,13128272 0,15363143 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13128272 0,15355674 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,13128272 0,15348213 ! chromosome condensation GO:0030261 45 25 0,000 0,13128272 0,15340758 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13128272 0,15333312 ! neural crest cell development GO:0014032 54 25 0,000 0,13128272 0,15325872 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13128272 0,15318439 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13128272 0,15311014 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,13128272 0,15303596 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13128272 0,15296185 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13128272 0,15288781 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13128272 0,15281384 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13128272 0,15273995 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13128272 0,15266613 ! telomere organization GO:0032200 43 25 0,000 0,13128272 0,15259238 GO:0000723|telomere maintenance, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13616153 0,15818669 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13616153 0,15811035 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13616153 0,15803408 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13616153 0,15795788 ! initiation of viral infection GO:0019059 57 26 0,000 0,13616153 0,15788175 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13616153 0,1578057 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13616153 0,15772973 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13616153 0,15765382 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13616153 0,15757799 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13616153 0,15750223 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,13616153 0,15742654 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13616153 0,15735093 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13616153 0,15727539 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13616153 0,15719992 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,13616153 0,15712453 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13616153 0,1570492 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13616153 0,15697395 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13616153 0,15689877 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13616153 0,15682367 ! blastocyst development GO:0001824 49 26 0,000 0,13616153 0,15674863 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13616153 0,15667367 ! neuron fate commitment GO:0048663 48 27 0,000 0,1410131 0,16217855 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,1410131 0,16210106 ! iron ion transport GO:0006826 59 27 0,000 0,1410131 0,16202365 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,1410131 0,16194631 ! superoxide metabolic process GO:0006801 38 27 0,000 0,1410131 0,16186905 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,1410131 0,16179186 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,1410131 0,16171474 ! autophagy GO:0006914 41 27 0,000 0,1410131 0,1616377 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,1410131 0,16156073 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,1410131 0,16148383 ! glutathione metabolic process GO:0006749 39 27 0,000 0,1410131 0,16140701 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,1410131 0,16133025 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,1410131 0,16125358 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,1410131 0,16117697 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14583759 0,16661217 ! circadian rhythm GO:0007623 50 28 0,000 0,14583759 0,1665331 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14583759 0,1664541 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,14583759 0,16637517 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14583759 0,16629632 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14583759 0,16621755 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14583759 0,16613884 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14583759 0,16606022 ! synaptogenesis GO:0007416 42 28 0,000 0,14583759 0,16598166 ! lipid oxidation GO:0034440 43 28 0,000 0,14583759 0,16590319 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14583759 0,16582478 ! translational initiation GO:0006413 65 29 0,000 0,15063514 0,17119893 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15063514 0,1711181 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15063514 0,17103735 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15063514 0,17095667 ! catechol metabolic process GO:0009712 54 29 0,000 0,15063514 0,17087607 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15063514 0,17079554 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15063514 0,17071509 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15063514 0,17063472 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15063514 0,17055442 ! cell fate determination GO:0001709 60 29 0,000 0,15063514 0,1704742 ! detection of light stimulus GO:0009583 38 29 0,000 0,15063514 0,17039405 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,15063514 0,17031398 ! phenol metabolic process GO:0018958 55 30 0,000 0,1554059 0,17562545 ! zinc ion transport GO:0006829 45 30 0,000 0,1554059 0,175543 ! membrane docking GO:0022406 61 30 0,000 0,1554059 0,17546063 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,1554059 0,17537833 ! regulation of innate immune response GO:0045088 51 30 0,000 0,1554059 0,17529611 ! acute-phase response GO:0006953 49 30 0,000 0,1554059 0,17521396 ! myofibril assembly GO:0030239 47 30 0,000 0,1554059 0,17513189 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,1554059 0,1750499 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,1554059 0,17496799 ! phospholipid transport GO:0015914 51 30 0,000 0,1554059 0,17488615 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,1554059 0,17480439 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,1554059 0,17472271 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,1554059 0,1746411 ! eye morphogenesis GO:0048592 60 30 0,000 0,1554059 0,17455957 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16015002 0,17980446 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16015002 0,17972059 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16015002 0,17963681 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16015002 0,1795531 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16015002 0,17946947 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16015002 0,17938592 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16015002 0,17930244 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16015002 0,17921905 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16015002 0,17913573 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16015002 0,17905249 ! peptide transport GO:0015833 55 31 0,000 0,16015002 0,17896932 ! mesoderm formation GO:0001707 69 31 0,000 0,16015002 0,17888624 ! natural killer cell activation GO:0030101 45 31 0,000 0,16015002 0,17880323 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16015002 0,17872029 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16015002 0,17863744 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,16015002 0,17855466 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16015002 0,17847196 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,16486765 0,18364425 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16486765 0,18355926 ! cholesterol transport GO:0030301 56 32 0,000 0,16486765 0,18347436 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16486765 0,18338954 ! spliceosome assembly GO:0000245 67 32 0,000 0,16486765 0,18330479 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,16486765 0,18322013 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16486765 0,18313554 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,16486765 0,18305103 ! muscle cell development GO:0055001 49 32 0,000 0,16486765 0,18296659 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16486765 0,18288224 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,16486765 0,18279796 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,16486765 0,18271376 ! BMP signaling pathway GO:0030509 64 32 0,000 0,16486765 0,18262964 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,16486765 0,18254559 ! gene silencing GO:0016458 65 32 0,000 0,16486765 0,18246162 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16955894 0,18756727 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,16955894 0,18748107 ! ceramide metabolic process GO:0006672 64 33 0,000 0,16955894 0,18739495 ! formation of primary germ layer GO:0001704 72 33 0,000 0,16955894 0,18730891 ! cell fate specification GO:0001708 52 33 0,000 0,16955894 0,18722295 ! sterol transport GO:0015918 57 33 0,000 0,16955894 0,18713707 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16955894 0,18705126 ! adult locomotory behavior GO:0008344 59 33 0,000 0,16955894 0,18696554 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,16955894 0,18687989 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,16955894 0,18679433 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,17422403 0,19184577 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,17422403 0,19175801 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17422403 0,19167033 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,17422403 0,19158273 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,17422403 0,19149521 ! mismatch repair GO:0006298 46 34 0,000 0,17422403 0,19140777 ! spermatid development GO:0007286 63 34 0,000 0,17422403 0,19132041 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17422403 0,19123313 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17422403 0,19114592 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,17886306 0,1961461 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,17886306 0,19605674 ! odontogenesis GO:0042476 66 35 0,000 0,17886306 0,19596746 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,17886306 0,19587826 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,17886306 0,19578914 ! vesicle localization GO:0051648 64 35 0,000 0,17886306 0,19570011 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,18347619 0,20065624 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,18347619 0,20056507 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18347619 0,20047399 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18347619 0,20038299 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,18347619 0,20029207 ! regulation of proteolysis GO:0030162 72 36 0,000 0,18347619 0,20020123 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18347619 0,20011048 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18347619 0,20001981 ! aerobic respiration GO:0009060 55 36 0,000 0,18347619 0,19992922 ! embryonic organ development GO:0048568 57 36 0,000 0,18347619 0,19983872 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18347619 0,19974829 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18806356 0,2046499 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,18806356 0,20455738 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,18806356 0,20446494 ! actomyosin structure organization GO:0031032 62 37 0,000 0,18806356 0,20437259 ! organic anion transport GO:0015711 68 37 0,000 0,18806356 0,20428033 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,18806356 0,20418814 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,18806356 0,20409604 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,18806356 0,20400402 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,18806356 0,20391209 ! spermatid differentiation GO:0048515 66 37 0,000 0,18806356 0,20382024 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,1926253 0,20867018 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,1926253 0,20857627 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,1926253 0,20848245 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,1926253 0,2083887 ! glucan metabolic process GO:0044042 62 38 0,000 0,1926253 0,20829505 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,19716157 0,21310455 ! learning GO:0007612 77 39 0,000 0,19716157 0,21300886 ! ion transmembrane transport GO:0034220 66 39 0,000 0,19716157 0,21291326 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,19716157 0,21281774 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,19716157 0,2127223 ! RNA modification GO:0009451 57 39 0,000 0,19716157 0,21262695 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,2016725 0,21739428 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,2016725 0,21729692 ! feeding behavior GO:0007631 59 40 0,000 0,2016725 0,21719965 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,2016725 0,21710247 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,2016725 0,21700538 ! maintenance of protein location GO:0045185 91 40 0,000 0,2016725 0,21690837 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,20615823 0,22163391 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,20615823 0,22153492 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,20615823 0,22143602 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,20615823 0,22133721 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,20615823 0,22123849 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,20615823 0,22113986 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,2106189 0,22582401 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,2106189 0,22572342 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,2106189 0,22562292 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,2106189 0,22552251 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,21505466 0,23016971 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,21505466 0,23006737 ! striated muscle contraction GO:0006941 77 43 0,000 0,21505466 0,22996512 ! phagocytosis GO:0006909 90 43 0,000 0,21505466 0,22986296 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,21505466 0,22976088 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,21946564 0,23436943 ! biopolymer methylation GO:0043414 84 44 0,000 0,21946564 0,23426545 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,21946564 0,23416156 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,21946564 0,23405777 ! maintenance of location in cell GO:0051651 97 44 0,000 0,21946564 0,23395407 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22385198 0,23852429 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,22385198 0,2384187 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22385198 0,23831321 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22385198 0,23820781 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22385198 0,2381025 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22385198 0,23799728 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22385198 0,23789216 ! cell growth GO:0016049 84 45 0,000 0,22385198 0,23778713 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,22821381 0,24231351 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,22821381 0,24220663 ! response to calcium ion GO:0051592 81 47 0,000 0,23255127 0,24670122 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,23255127 0,24659249 ! methylation GO:0032259 90 47 0,000 0,23255127 0,24648386 ! Notch signaling pathway GO:0007219 96 48 0,000 0,2368645 0,25094495 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,2368645 0,2508345 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24115363 0,25526425 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,24115363 0,255152 ! peptide metabolic process GO:0006518 76 49 0,000 0,24115363 0,25503984 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24115363 0,25492779 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,24115363 0,25481583 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24115363 0,25470397 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24115363 0,25459221 ! neuromuscular process GO:0050905 99 50 0,000 0,2454188 0,25898142 ! inner ear development GO:0048839 79 50 0,000 0,2454188 0,25886788 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,2454188 0,25875444 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,2454188 0,2586411 ! viral infectious cycle GO:0019058 99 51 0,000 0,24966013 0,26299575 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,24966013 0,26288065 ! excretion GO:0007588 83 51 0,000 0,24966013 0,26276565 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,24966013 0,26265076 ! chromatin remodeling GO:0006338 109 51 0,000 0,24966013 0,26253596 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,24966013 0,26242127 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,24966013 0,26230667 ! membrane fusion GO:0006944 110 52 0,000 0,25387777 0,26662153 ! amino acid activation GO:0043038 92 52 0,000 0,25387777 0,2665052 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,25807184 0,27078973 ! RNA catabolic process GO:0006401 93 53 0,000 0,25807184 0,27067168 ! regulation of translational initiation GO:0006446 82 53 0,000 0,25807184 0,27055374 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,25807184 0,27043591 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,25807184 0,27031817 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,25807184 0,27020054 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,25807184 0,27008301 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,26224247 0,27432843 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,26224247 0,27420921 ! cell recognition GO:0008037 85 54 0,000 0,26224247 0,27409009 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,26224247 0,27397107 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,26224247 0,27385216 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,26224247 0,27373335 ! chloride transport GO:0006821 90 55 0,000 0,26638979 0,27794182 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,26638979 0,27782135 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,26638979 0,27770097 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,26638979 0,2775807 ! gastrulation GO:0007369 112 55 0,000 0,26638979 0,27746054 ! RNA elongation GO:0006354 79 55 0,000 0,26638979 0,27734048 ! regulation of actin filament length GO:0030832 105 56 0,000 0,27051394 0,28151235 ! sensory perception of smell GO:0007608 80 56 0,000 0,27051394 0,28139064 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27051394 0,28126903 ! proton transport GO:0015992 94 56 0,000 0,27051394 0,28114754 ! maintenance of location GO:0051235 118 57 0,000 0,27461504 0,28528661 ! hydrogen transport GO:0006818 97 58 0,000 0,27869322 0,28939831 ! regulation of endocytosis GO:0030100 91 58 0,000 0,27869322 0,28927346 ! adult behavior GO:0030534 99 58 0,000 0,27869322 0,28914872 ! regulation of cellular component size GO:0032535 109 59 0,000 0,28274861 0,2932298 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28274861 0,29310347 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,28274861 0,29297724 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,28274861 0,29285112 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,28678133 0,29690012 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,28678133 0,29677242 ! camera-type eye development GO:0043010 116 60 0,000 0,28678133 0,29664483 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,2907915 0,30066367 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,2907915 0,30053452 ! mesoderm development GO:0007498 119 61 0,000 0,2907915 0,30040548 ! tRNA processing GO:0008033 89 61 0,000 0,2907915 0,30027655 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2907915 0,30014773 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,29477927 0,30413333 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,29874474 0,30809252 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,29874474 0,30796052 ! cell redox homeostasis GO:0045454 102 64 0,000 0,30268805 0,31189184 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,30268805 0,31175832 ! single fertilization GO:0007338 75 64 0,000 0,30268805 0,31162492 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,30660931 0,31552695 ! extracellular matrix organization GO:0030198 133 66 0,000 0,31050865 0,31940309 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,3143862 0,3232535 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,3143862 0,32311542 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,3143862 0,32297745 ! activation of immune response GO:0002253 105 67 0,000 0,3143862 0,3228396 ! amino acid transport GO:0006865 125 68 0,000 0,31824206 0,32665973 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,31824206 0,32652043 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,31824206 0,32638124 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,31824206 0,32624218 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,31824206 0,32610324 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,32207637 0,32989176 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,32207637 0,32975138 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,32207637 0,32961112 ! antigen processing and presentation GO:0019882 104 69 0,000 0,32207637 0,32947098 ! amine catabolic process GO:0009310 117 71 0,000 0,32968079 0,33710666 ! regulation of immune effector process GO:0002697 137 71 0,000 0,32968079 0,33696346 ! acute inflammatory response GO:0002526 113 72 0,000 0,33345114 0,34067237 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,33345114 0,34052778 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,33345114 0,3403833 ! learning or memory GO:0007611 147 73 0,000 0,33720041 0,34406454 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,33720041 0,34391869 ! fertilization GO:0009566 90 73 0,000 0,33720041 0,34377296 ! transition metal ion transport GO:0000041 126 74 0,000 0,34092871 0,34742672 ! neurotransmitter transport GO:0006836 123 74 0,000 0,34092871 0,34727963 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,34092871 0,34713266 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,34092871 0,34698582 ! eye development GO:0001654 143 74 0,000 0,34092871 0,3468391 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,34463616 0,35046264 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,34463616 0,35031458 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,34832289 0,35391253 ! defense response to bacterium GO:0042742 89 76 0,000 0,34832289 0,35376313 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,35198899 0,35733566 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,35198899 0,35718495 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,35198899 0,35703436 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,35563459 0,3605802 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,3592598 0,3641024 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,3592598 0,36394909 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,3592598 0,36379591 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,3592598 0,36364286 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,36286474 0,36713733 ! inorganic anion transport GO:0015698 138 80 0,000 0,36286474 0,366983 ! digestion GO:0007586 112 81 0,000 0,36644951 0,37045274 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,36644951 0,37029716 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,37001424 0,37374234 ! regulation of ligase activity GO:0051340 142 84 0,000 0,37708398 0,38072348 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,37708398 0,38056378 ! response to unfolded protein GO:0006986 131 85 0,000 0,38058922 0,38394032 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,38058922 0,3837794 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,38407484 0,387132 ! amine transport GO:0015837 155 86 0,000 0,38407484 0,38696988 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,38754097 0,3902987 ! cellular respiration GO:0045333 135 88 0,000 0,39098771 0,3936052 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39098771 0,39344059 ! cellular defense response GO:0006968 114 89 0,000 0,39441517 0,39672362 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,40121266 0,40339225 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,40458291 0,40661089 ! vitamin metabolic process GO:0006766 139 92 0,000 0,40458291 0,40644112 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,4079343 0,40963686 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,4079343 0,40946597 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,41126694 0,41263897 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,41787637 0,41909568 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,41787637 0,41892106 ! positive regulation of immune response GO:0050778 156 96 0,000 0,41787637 0,41874658 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,42115337 0,42185471 ! protein ubiquitination GO:0016567 217 97 0,000 0,42115337 0,42167916 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,42441204 0,42476512 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,42441204 0,42458851 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,42765246 0,42765246