pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6558-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! carbohydrate homeostasis GO:0033500 59 39 7,000 2,82E-11 6,889E-08 GO:0042593|glucose homeostasis, ! positive regulation of MAP kinase activity GO:0043406 174 93 9,000 7,441E-11 9,09E-08 ! organ growth GO:0035265 15 7 4,000 8,171E-11 6,654E-08 ! cell cycle checkpoint GO:0000075 145 71 8,000 1,501E-10 9,165E-08 ! positive regulation of hormone secretion GO:0046887 35 19 5,000 5,178E-10 2,53E-07 ! DNA damage checkpoint GO:0000077 78 35 6,000 6,142E-10 2,501E-07 ! DNA integrity checkpoint GO:0031570 82 38 6,000 1,137E-09 3,969E-07 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 1,767E-09 5,396E-07 ! activation of MAPK activity GO:0000187 124 67 7,000 2,635E-09 7,153E-07 ! interphase of mitotic cell cycle GO:0051329 224 98 8,000 2,805E-09 6,853E-07 ! regulation of insulin secretion GO:0050796 42 25 5,000 3,292E-09 7,312E-07 ! regulation of peptide secretion GO:0002791 52 29 5,000 8,676E-09 1,766E-06 ! regulation of multicellular organism growth GO:0040014 90 55 6,000 1,695E-08 3,186E-06 ! negative regulation of transport GO:0051051 164 85 7,000 1,793E-08 3,129E-06 ! cellular response to hormone stimulus GO:0032870 182 85 7,000 1,793E-08 2,92E-06 ! regulation of protein export from nucleus GO:0046825 10 7 3,000 2,62E-08 4,001E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 2,62E-08 3,766E-06 GO:0046676|negative regulation of insulin secretion, ! DNA damage response, signal transduction GO:0042770 136 62 6,000 3,982E-08 5,405E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 5,219E-08 6,71E-06 ! regulation of hormone secretion GO:0046883 69 41 5,000 7,791E-08 9,517E-06 ! negative regulation of protein kinase activity GO:0006469 144 69 6,000 8,468E-08 9,852E-06 ! induction of positive chemotaxis GO:0050930 17 9 3,000 9,355E-08 1,039E-05 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 3,000 9,355E-08 9,937E-06 ! negative regulation of kinase activity GO:0033673 145 70 6,000 9,368E-08 9,535E-06 ! negative regulation of transferase activity GO:0051348 155 74 6,000 1,381E-07 1,35E-05 ! induction of apoptosis by intracellular signals GO:0008629 95 45 5,000 1,387E-07 1,303E-05 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 5,000 1,588E-07 1,437E-05 ! fat cell differentiation GO:0045444 57 28 4,000 3,494E-07 3,049E-05 ! negative regulation of growth GO:0045926 168 85 6,000 3,608E-07 3,039E-05 ! regulation of positive chemotaxis GO:0050926 22 12 3,000 3,63E-07 2,956E-05 GO:0050927|positive regulation of positive chemotaxis, ! release of cytochrome c from mitochondria GO:0001836 31 14 3,000 7,28E-07 5,737E-05 ! positive regulation of secretion GO:0051047 110 61 5,000 8,813E-07 6,728E-05 ! negative regulation of bone remodeling GO:0046851 34 15 3,000 9,886E-07 7,318E-05 ! negative regulation of secretion GO:0051048 68 35 4,000 1,12E-06 8,048E-05 ! response to peptide hormone stimulus GO:0043434 129 64 5,000 1,175E-06 8,198E-05 ! negative regulation of tissue remodeling GO:0034104 37 16 3,000 1,313E-06 8,908E-05 ! positive regulation of muscle development GO:0048636 15 5 2,000 1,445E-06 9,541E-05 GO:0045844|positive regulation of striated muscle development, ! regulation of mitochondrial membrane permeability GO:0046902 15 5 2,000 1,445E-06 9,29E-05 ! negative regulation of cell growth GO:0030308 142 67 5,000 1,543E-06 9,665E-05 ! negative regulation of hormone secretion GO:0046888 26 17 3,000 1,709E-06 1,044E-04 ! cellular response to insulin stimulus GO:0032869 85 38 4,000 1,71E-06 1,019E-04 ! negative regulation of cell size GO:0045792 144 69 5,000 1,837E-06 1,069E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 2,879E-06 1,635E-04 ! L-serine biosynthetic process GO:0006564 7 6 2,000 2,879E-06 1,598E-04 ! pancreas development GO:0031016 40 20 3,000 3,437E-06 1,866E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 3,437E-06 1,825E-04 ! positive regulation of response to external stimulus GO:0032103 88 44 4,000 3,605E-06 1,874E-04 ! positive regulation of inflammatory response GO:0050729 41 21 3,000 4,228E-06 2,152E-04 ! fibrinolysis GO:0042730 11 7 2,000 5,018E-06 2,502E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 5,018E-06 2,452E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 5,018E-06 2,404E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 5,018E-06 2,357E-04 ! response to insulin stimulus GO:0032868 98 47 4,000 5,027E-06 2,317E-04 ! positive regulation of locomotion GO:0040017 44 22 3,000 5,146E-06 2,328E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of inflammatory response GO:0050727 84 48 4,000 5,588E-06 2,482E-04 ! regulation of chemotaxis GO:0050920 45 23 3,000 6,204E-06 2,707E-04 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 7,414E-06 3,178E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 7,997E-06 3,369E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 7,997E-06 3,311E-04 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 3,000 8,79E-06 3,579E-04 ! regulation of behavior GO:0050795 48 25 3,000 8,79E-06 3,52E-04 ! positive regulation of growth GO:0045927 96 53 4,000 9,166E-06 3,612E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 1,035E-05 4,012E-04 GO:0045936|negative regulation of phosphate metabolic process, ! response to UV GO:0009411 120 55 4,000 1,102E-05 4,205E-04 ! negative regulation of multicellular organismal process GO:0051241 174 95 5,000 1,189E-05 4,468E-04 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 1,209E-05 4,477E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 1,315E-05 4,794E-04 ! regulation of bone remodeling GO:0046850 143 57 4,000 1,315E-05 4,723E-04 ! regulation of protein localization GO:0032880 188 97 5,000 1,34E-05 4,744E-04 ! regulation of fibroblast proliferation GO:0048145 56 28 3,000 1,405E-05 4,904E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 3,000 1,405E-05 4,835E-04 ! positive regulation of cell migration GO:0030335 137 58 4,000 1,433E-05 4,861E-04 ! regulation of tissue remodeling GO:0034103 146 58 4,000 1,433E-05 4,794E-04 ! regulation of developmental growth GO:0048638 16 10 2,000 1,7E-05 5,614E-04 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 1,7E-05 5,539E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,7E-05 5,466E-04 ! regulation of homeostatic process GO:0032844 148 62 4,000 1,989E-05 6,31E-04 ! L-serine metabolic process GO:0006563 21 11 2,000 2,329E-05 7,294E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 2,329E-05 7,202E-04 ! negative regulation of ossification GO:0030279 27 11 2,000 2,329E-05 7,112E-04 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 2,329E-05 7,024E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 2,329E-05 6,938E-04 GO:0010829|negative regulation of glucose transport, ! multicellular organism reproduction GO:0032504 123 65 4,000 2,506E-05 7,377E-04 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 157 65 4,000 2,506E-05 7,289E-04 ! triglyceride metabolic process GO:0006641 46 33 3,000 2,751E-05 7,906E-04 ! focal adhesion formation GO:0048041 37 12 2,000 3,093E-05 8,787E-04 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 3,093E-05 8,686E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 4,000 3,352E-05 9,307E-04 ! regulation of striated muscle tissue development GO:0016202 81 35 3,000 3,491E-05 9,582E-04 ! regulation of muscle development GO:0048634 82 36 3,000 3,911E-05 1,062E-03 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 4,367E-05 1,172E-03 ! meiosis I GO:0007127 74 38 3,000 4,861E-05 1,291E-03 ! neutral lipid metabolic process GO:0006638 54 38 3,000 4,861E-05 1,277E-03 GO:0006639|acylglycerol metabolic process, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 5,078E-05 1,32E-03 ! response to gamma radiation GO:0010332 30 14 2,000 5,078E-05 1,306E-03 ! serine family amino acid biosynthetic process GO:0009070 19 14 2,000 5,078E-05 1,292E-03 ! glycerol ether metabolic process GO:0006662 57 40 3,000 5,969E-05 1,503E-03 ! regulation of skeletal muscle tissue development GO:0048641 35 15 2,000 6,323E-05 1,576E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 6,323E-05 1,56E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 6,323E-05 1,545E-03 ! mesenchymal cell development GO:0014031 94 41 3,000 6,587E-05 1,593E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! organic ether metabolic process GO:0018904 59 42 3,000 7,25E-05 1,736E-03 ! regulation of intracellular protein transport GO:0033157 86 42 3,000 7,25E-05 1,72E-03 ! meiosis GO:0007126 143 81 4,000 7,261E-05 1,706E-03 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 4,000 7,261E-05 1,689E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 7,261E-05 1,673E-03 ! meiotic cell cycle GO:0051321 144 82 4,000 7,7E-05 1,758E-03 ! hormone-mediated signaling GO:0009755 84 43 3,000 7,961E-05 1,801E-03 ! response to oxygen levels GO:0070482 183 83 4,000 8,158E-05 1,829E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 8,158E-05 1,812E-03 GO:0045937|positive regulation of phosphate metabolic process, ! myoblast differentiation GO:0045445 50 17 2,000 9,376E-05 2,064E-03 ! activation of MAPKK activity GO:0000186 43 17 2,000 9,376E-05 2,045E-03 ! regulation of protein binding GO:0043393 33 17 2,000 9,376E-05 2,027E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 9,376E-05 2,009E-03 ! negative regulation of blood coagulation GO:0030195 25 17 2,000 9,376E-05 1,992E-03 ! negative regulation of homeostatic process GO:0032845 36 17 2,000 9,376E-05 1,975E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 9,532E-05 1,99E-03 ! regulation of protein transport GO:0051223 165 87 4,000 1,021E-04 2,113E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 1,04E-04 2,134E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 1,121E-04 2,282E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,121E-04 2,263E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 1,23E-04 2,462E-03 ! positive regulation of defense response GO:0031349 88 48 3,000 1,23E-04 2,442E-03 ! regulation of ossification GO:0030278 123 50 3,000 1,443E-04 2,844E-03 ! regulation of defense response GO:0031347 171 95 4,000 1,547E-04 3,023E-03 ! response to alkaloid GO:0043279 38 20 2,000 1,554E-04 3,012E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,554E-04 2,988E-03 GO:0010827|regulation of glucose transport, ! negative regulation of translation GO:0017148 32 20 2,000 1,554E-04 2,965E-03 ! negative regulation of coagulation GO:0050819 30 20 2,000 1,554E-04 2,942E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,805E-04 3,393E-03 ! regulation of muscle contraction GO:0006937 94 54 3,000 1,95E-04 3,636E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 1,968E-04 3,642E-03 GO:0060538|skeletal muscle organ development, ! reciprocal meiotic recombination GO:0007131 44 22 2,000 2,082E-04 3,825E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 2,082E-04 3,796E-03 ! cell aging GO:0007569 48 22 2,000 2,082E-04 3,768E-03 ! G1 phase GO:0051318 44 22 2,000 2,082E-04 3,741E-03 ! response to glucocorticoid stimulus GO:0051384 42 22 2,000 2,082E-04 3,713E-03 ! skeletal muscle fiber development GO:0048741 130 56 3,000 2,246E-04 3,975E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 2,000 2,385E-04 4,193E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 2,385E-04 4,163E-03 ! muscle fiber development GO:0048747 131 57 3,000 2,405E-04 4,167E-03 ! regulation of intracellular transport GO:0032386 108 57 3,000 2,405E-04 4,138E-03 ! positive regulation of cell adhesion GO:0045785 61 24 2,000 2,716E-04 4,639E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 2,716E-04 4,607E-03 ! response to corticosteroid stimulus GO:0031960 46 24 2,000 2,716E-04 4,575E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,754E-04 4,608E-03 ! hypothalamus development GO:0021854 9 5 1,000 2,754E-04 4,577E-03 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 1,000 2,754E-04 4,546E-03 ! adaptation of signaling pathway GO:0022401 7 5 1,000 2,754E-04 4,515E-03 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,754E-04 4,485E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,754E-04 4,455E-03 ! microvillus organization GO:0032528 8 5 1,000 2,754E-04 4,426E-03 GO:0030033|microvillus assembly, ! muscle cell migration GO:0014812 8 5 1,000 2,754E-04 4,397E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,754E-04 4,368E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,754E-04 4,34E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 2,754E-04 4,312E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,754E-04 4,285E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,754E-04 4,258E-03 ! brown fat cell differentiation GO:0050873 7 5 1,000 2,754E-04 4,231E-03 ! regulation of mitochondrial depolarization GO:0051900 14 5 1,000 2,754E-04 4,205E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,754E-04 4,179E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 2,754E-04 4,153E-03 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 2,754E-04 4,127E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,754E-04 4,102E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 2,754E-04 4,077E-03 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 1,000 2,754E-04 4,053E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 3,074E-04 4,497E-03 ! protein tetramerization GO:0051262 57 25 2,000 3,074E-04 4,47E-03 ! regulation of heart contraction GO:0008016 123 61 3,000 3,126E-04 4,518E-03 ! negative regulation of response to stimulus GO:0048585 106 61 3,000 3,126E-04 4,492E-03 ! myelination GO:0042552 50 26 2,000 3,461E-04 4,945E-03 ! regulation of blood coagulation GO:0030193 46 26 2,000 3,461E-04 4,916E-03 ! positive regulation of nuclear division GO:0051785 41 26 2,000 3,461E-04 4,888E-03 GO:0045840|positive regulation of mitosis, ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 3,759E-04 5,278E-03 ! mitochondrial membrane organization GO:0007006 60 27 2,000 3,879E-04 5,415E-03 ! response to toxin GO:0009636 49 27 2,000 3,879E-04 5,384E-03 ! regulation of chromosome organization GO:0033044 49 27 2,000 3,879E-04 5,354E-03 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 4,116E-04 5,649E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 4,116E-04 5,618E-03 ! hyperosmotic response GO:0006972 10 6 1,000 4,116E-04 5,587E-03 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 1,000 4,116E-04 5,556E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 4,116E-04 5,525E-03 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 19 6 1,000 4,116E-04 5,495E-03 ! astrocyte development GO:0014002 16 6 1,000 4,116E-04 5,465E-03 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 4,116E-04 5,436E-03 ! Schwann cell development GO:0014044 15 6 1,000 4,116E-04 5,406E-03 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 4,116E-04 5,378E-03 ! negative regulation of multicellular organism growth GO:0040015 9 6 1,000 4,116E-04 5,349E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 4,116E-04 5,321E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,116E-04 5,293E-03 ! negative regulation of smooth muscle contraction GO:0045986 12 6 1,000 4,116E-04 5,265E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 4,229E-04 5,381E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 4,328E-04 5,478E-03 ! positive regulation of multicellular organism growth GO:0040018 55 30 2,000 5,322E-04 6,702E-03 ! tissue homeostasis GO:0001894 50 30 2,000 5,322E-04 6,667E-03 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 2,000 5,322E-04 6,633E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 5,585E-04 6,926E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 5,743E-04 7,086E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 5,743E-04 7,05E-03 ! mRNA stabilization GO:0048255 18 7 1,000 5,743E-04 7,015E-03 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,743E-04 6,98E-03 ! lipoprotein transport GO:0042953 14 7 1,000 5,743E-04 6,945E-03 ! regulation of granule cell precursor proliferation GO:0021936 12 7 1,000 5,743E-04 6,911E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! response to dietary excess GO:0002021 8 7 1,000 5,743E-04 6,877E-03 ! male sex determination GO:0030238 15 7 1,000 5,743E-04 6,844E-03 ! monocyte differentiation GO:0030224 16 7 1,000 5,743E-04 6,81E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 5,743E-04 6,777E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 1,000 5,743E-04 6,745E-03 ! peptidyl-threonine modification GO:0018210 26 7 1,000 5,743E-04 6,713E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 5,743E-04 6,681E-03 ! endosome to lysosome transport GO:0008333 12 7 1,000 5,743E-04 6,649E-03 ! cell junction assembly GO:0034329 85 31 2,000 5,869E-04 6,763E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 5,869E-04 6,732E-03 ! ensheathment of neurons GO:0007272 64 31 2,000 5,869E-04 6,7E-03 GO:0008366|axon ensheathment, ! peripheral nervous system development GO:0007422 68 32 2,000 6,451E-04 7,33E-03 ! response to ionizing radiation GO:0010212 74 33 2,000 7,069E-04 7,995E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 7,069E-04 7,958E-03 GO:0060326|cell chemotaxis, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 1,000 7,63E-04 8,551E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 7,63E-04 8,512E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 7,63E-04 8,473E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 7,63E-04 8,435E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,63E-04 8,397E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,63E-04 8,359E-03 ! pigment granule organization GO:0048753 17 8 1,000 7,63E-04 8,322E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,63E-04 8,285E-03 ! astrocyte differentiation GO:0048708 19 8 1,000 7,63E-04 8,248E-03 ! ER overload response GO:0006983 13 8 1,000 7,63E-04 8,212E-03 ! regulation of pigmentation during development GO:0048070 25 8 1,000 7,63E-04 8,176E-03 ! melanin metabolic process GO:0006582 17 8 1,000 7,63E-04 8,14E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,63E-04 8,105E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,63E-04 8,07E-03 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 1,000 7,63E-04 8,035E-03 ! positive regulation of vasodilation GO:0045909 14 8 1,000 7,63E-04 8E-03 ! Schwann cell differentiation GO:0014037 21 8 1,000 7,63E-04 7,966E-03 ! response to UV-B GO:0010224 17 8 1,000 7,63E-04 7,932E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 7,63E-04 7,899E-03 ! response to tumor cell GO:0002347 16 8 1,000 7,63E-04 7,865E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 7,63E-04 7,832E-03 ! negative regulation of calcium ion transport GO:0051926 13 8 1,000 7,63E-04 7,799E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 7,63E-04 7,767E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 7,723E-04 7,828E-03 ! serine family amino acid metabolic process GO:0009069 56 34 2,000 7,723E-04 7,796E-03 ! blood coagulation GO:0007596 151 79 3,000 8,358E-04 8,403E-03 GO:0050817|coagulation, ! protein oligomerization GO:0051259 149 79 3,000 8,358E-04 8,368E-03 ! placenta development GO:0001890 53 35 2,000 8,414E-04 8,39E-03 ! activation of protein kinase activity GO:0032147 170 80 3,000 8,762E-04 8,701E-03 ! muscle cell differentiation GO:0042692 178 81 3,000 9,179E-04 9,079E-03 ! cell-substrate adhesion GO:0031589 189 82 3,000 9,61E-04 9,467E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,776E-04 9,592E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 9,776E-04 9,553E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 9,776E-04 9,515E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 9,776E-04 9,477E-03 ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 9,776E-04 9,44E-03 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 9,776E-04 9,403E-03 ! regulation of telomere maintenance GO:0032204 17 9 1,000 9,776E-04 9,366E-03 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 1,000 9,776E-04 9,329E-03 ! cell proliferation in forebrain GO:0021846 18 9 1,000 9,776E-04 9,293E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 9,776E-04 9,257E-03 GO:0010469|regulation of receptor activity, ! cerebral cortex cell migration GO:0021795 18 9 1,000 9,776E-04 9,221E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,776E-04 9,186E-03 ! T cell selection GO:0045058 27 9 1,000 9,776E-04 9,151E-03 ! negative regulation of muscle contraction GO:0045932 16 9 1,000 9,776E-04 9,116E-03 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 2,000 9,912E-04 9,207E-03 ! cell junction organization GO:0034330 96 37 2,000 9,912E-04 9,172E-03 ! tissue remodeling GO:0048771 78 37 2,000 9,912E-04 9,137E-03 ! response to drug GO:0042493 149 83 3,000 1,006E-03 9,235E-03 ! hemostasis GO:0007599 165 85 3,000 1,099E-03 0,01005507 ! mitochondrion organization GO:0007005 159 87 3,000 1,198E-03 0,01092266 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 1,218E-03 0,01105956 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,218E-03 0,0110186 ! negative regulation of blood pressure GO:0045776 26 10 1,000 1,218E-03 0,01097794 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,218E-03 0,01093758 ! positive regulation of heart contraction GO:0045823 17 10 1,000 1,218E-03 0,01089752 ! lung alveolus development GO:0048286 26 10 1,000 1,218E-03 0,01085774 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 1,218E-03 0,01081826 ! B cell proliferation GO:0042100 19 10 1,000 1,218E-03 0,01077907 ! regulation of sodium ion transport GO:0002028 26 10 1,000 1,218E-03 0,01074015 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,218E-03 0,01070152 ! motor axon guidance GO:0008045 22 10 1,000 1,218E-03 0,01066316 ! regulation of bone resorption GO:0045124 25 10 1,000 1,218E-03 0,01062508 ! protein heterooligomerization GO:0051291 17 10 1,000 1,218E-03 0,01058727 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 1,218E-03 0,01054972 ! regulation of fat cell differentiation GO:0045598 18 10 1,000 1,218E-03 0,01051245 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,218E-03 0,01047543 GO:0043470|regulation of carbohydrate catabolic process, ! response to nicotine GO:0035094 20 10 1,000 1,218E-03 0,01043867 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,218E-03 0,01040217 ! lipid homeostasis GO:0055088 75 40 2,000 1,246E-03 0,01060396 ! regulation of action potential in neuron GO:0019228 80 40 2,000 1,246E-03 0,01056714 ! tube morphogenesis GO:0035239 194 89 3,000 1,304E-03 0,01102002 ! gliogenesis GO:0042063 91 41 2,000 1,339E-03 0,01127895 ! gland development GO:0048732 220 91 3,000 1,415E-03 0,0118822 ! T cell differentiation GO:0030217 93 42 2,000 1,436E-03 0,01201671 ! regulation of cell adhesion GO:0030155 241 92 3,000 1,474E-03 0,01228711 ! negative regulation of muscle development GO:0048635 27 11 1,000 1,483E-03 0,01232481 ! telencephalon cell migration GO:0022029 23 11 1,000 1,483E-03 0,01228303 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,483E-03 0,01224154 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,483E-03 0,01220032 ! blood vessel remodeling GO:0001974 30 11 1,000 1,483E-03 0,01215938 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,483E-03 0,01211871 ! bone resorption GO:0045453 16 11 1,000 1,483E-03 0,01207832 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,483E-03 0,01203819 ! regulation of intracellular pH GO:0051453 21 11 1,000 1,483E-03 0,01199833 ! temperature homeostasis GO:0001659 18 11 1,000 1,483E-03 0,01195873 ! behavioral fear response GO:0001662 27 11 1,000 1,483E-03 0,01191939 GO:0002209|behavioral defense response, ! alpha-beta T cell activation GO:0046631 26 11 1,000 1,483E-03 0,01188031 ! nitric oxide metabolic process GO:0046209 17 11 1,000 1,483E-03 0,01184149 GO:0006809|nitric oxide biosynthetic process, ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,483E-03 0,01180291 ! thymus development GO:0048538 29 11 1,000 1,483E-03 0,01176459 ! oocyte development GO:0048599 20 11 1,000 1,483E-03 0,01172652 ! regulation of embryonic development GO:0045995 35 11 1,000 1,483E-03 0,01168869 ! neuron migration GO:0001764 85 43 2,000 1,538E-03 0,01208186 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 1,538E-03 0,01204314 ! regulation of membrane potential GO:0042391 179 94 3,000 1,595E-03 0,01245078 ! double-strand break repair GO:0006302 85 44 2,000 1,644E-03 0,01279237 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 1,755E-03 0,0136098 ! B cell differentiation GO:0030183 124 45 2,000 1,755E-03 0,01356673 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,774E-03 0,01366902 ! virus-host interaction GO:0019048 30 12 1,000 1,774E-03 0,01362604 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,774E-03 0,01358332 ! forebrain cell migration GO:0021885 24 12 1,000 1,774E-03 0,01354088 ! histone acetylation GO:0016573 27 12 1,000 1,774E-03 0,01349869 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,774E-03 0,01345677 ! T cell homeostasis GO:0043029 28 12 1,000 1,774E-03 0,01341511 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,774E-03 0,01337371 ! oocyte differentiation GO:0009994 21 12 1,000 1,774E-03 0,01333256 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,774E-03 0,01329166 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,774E-03 0,01325101 ! response to cold GO:0009409 17 12 1,000 1,774E-03 0,01321061 ! localization within membrane GO:0051668 26 12 1,000 1,774E-03 0,01317046 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 1,79E-03 0,01325415 ! leukocyte differentiation GO:0002521 232 98 3,000 1,859E-03 0,01372018 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,87E-03 0,01376044 ! leukocyte migration GO:0050900 75 46 2,000 1,87E-03 0,01371911 ! negative regulation of cell migration GO:0030336 122 46 2,000 1,87E-03 0,01367804 ! pigmentation GO:0043473 103 46 2,000 1,87E-03 0,01363721 ! hormone metabolic process GO:0042445 171 100 3,000 2,001E-03 0,01455251 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,089E-03 0,0151428 GO:0000725|recombinational repair, ! endocrine pancreas development GO:0031018 25 13 1,000 2,089E-03 0,01509799 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,089E-03 0,01505346 ! response to X-ray GO:0010165 28 13 1,000 2,089E-03 0,01500918 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,089E-03 0,01496517 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 2,089E-03 0,01492141 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,089E-03 0,01487791 ! gland morphogenesis GO:0022612 31 13 1,000 2,089E-03 0,01483466 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 2,089E-03 0,01479166 ! spleen development GO:0048536 24 13 1,000 2,089E-03 0,01474891 ! regulation of mRNA stability GO:0043488 32 13 1,000 2,089E-03 0,0147064 ! digestive tract morphogenesis GO:0048546 31 13 1,000 2,089E-03 0,01466414 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! mitochondrial transport GO:0006839 94 48 2,000 2,114E-03 0,01479985 ! vascular process in circulatory system GO:0003018 85 48 2,000 2,114E-03 0,01475757 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,243E-03 0,01561471 ! regulation of action potential GO:0001508 102 50 2,000 2,377E-03 0,01650026 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 2,377E-03 0,01645352 ! endocrine system development GO:0035270 109 50 2,000 2,377E-03 0,01640704 ! activation of caspase activity GO:0006919 95 50 2,000 2,377E-03 0,01636083 ! hair follicle morphogenesis GO:0031069 27 14 1,000 2,429E-03 0,01666564 ! fear response GO:0042596 34 14 1,000 2,429E-03 0,01661895 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 2,429E-03 0,01657253 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 37 14 1,000 2,429E-03 0,01652637 ! regulation of cellular pH GO:0030641 27 14 1,000 2,429E-03 0,01648046 ! positive regulation of bone mineralization GO:0030501 32 14 1,000 2,429E-03 0,01643481 ! regulation of RNA stability GO:0043487 33 14 1,000 2,429E-03 0,01638941 ! response to temperature stimulus GO:0009266 84 51 2,000 2,516E-03 0,01693467 ! cellular amino acid biosynthetic process GO:0008652 80 52 2,000 2,66E-03 0,01785297 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 2,66E-03 0,01780405 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,792E-03 0,01863925 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 2,792E-03 0,01858847 ! G1/S transition checkpoint GO:0031575 37 15 1,000 2,792E-03 0,01853795 ! positive regulation of biomineral formation GO:0070169 33 15 1,000 2,792E-03 0,01848772 ! regulation of vasodilation GO:0042312 27 15 1,000 2,792E-03 0,01843775 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,792E-03 0,01838805 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,792E-03 0,01833862 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 2,809E-03 0,0183963 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 2,000 2,809E-03 0,01834711 ! cartilage development GO:0051216 99 53 2,000 2,809E-03 0,01829819 ! regulation of angiogenesis GO:0045765 125 54 2,000 2,963E-03 0,01924851 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 2,963E-03 0,01919745 ! negative regulation of cell motion GO:0051271 142 55 2,000 3,121E-03 0,02017321 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,18E-03 0,02049995 ! bone remodeling GO:0046849 28 16 1,000 3,18E-03 0,020446 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 3,18E-03 0,02039234 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 3,18E-03 0,02033896 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! pituitary gland development GO:0021983 30 16 1,000 3,18E-03 0,02028585 ! response to osmotic stress GO:0006970 27 16 1,000 3,18E-03 0,02023302 ! lysosomal transport GO:0007041 31 16 1,000 3,18E-03 0,02018047 ! negative regulation of inflammatory response GO:0050728 24 16 1,000 3,18E-03 0,02012819 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 3,18E-03 0,02007618 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,18E-03 0,02002444 ! regulation of DNA replication GO:0006275 105 56 2,000 3,285E-03 0,02063252 ! positive regulation of caspase activity GO:0043280 108 57 2,000 3,454E-03 0,02163923 GO:0010952|positive regulation of peptidase activity, ! metencephalon development GO:0022037 32 17 1,000 3,592E-03 0,02244213 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,592E-03 0,02238488 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 3,592E-03 0,02232792 ! glial cell development GO:0021782 28 17 1,000 3,592E-03 0,02227125 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 3,592E-03 0,02221486 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,592E-03 0,02215877 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 3,592E-03 0,02210295 ! aging GO:0007568 112 58 2,000 3,629E-03 0,02227473 ! positive regulation of organelle organization GO:0010638 108 58 2,000 3,629E-03 0,0222189 ! limbic system development GO:0021761 40 18 1,000 4,027E-03 0,02459376 ! negative regulation of ion transport GO:0043271 25 18 1,000 4,027E-03 0,02453243 ! regulation of viral genome replication GO:0045069 30 18 1,000 4,027E-03 0,02447141 ! epidermis morphogenesis GO:0048730 43 18 1,000 4,027E-03 0,02441068 ! long-chain fatty acid transport GO:0015909 32 18 1,000 4,027E-03 0,02435026 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,027E-03 0,02429014 ! defense response to virus GO:0051607 43 18 1,000 4,027E-03 0,02423031 ! negative regulation of defense response GO:0031348 27 19 1,000 4,485E-03 0,02692078 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 4,485E-03 0,0268548 ! protein amino acid ADP-ribosylation GO:0006471 37 19 1,000 4,485E-03 0,02678914 ! inositol metabolic process GO:0006020 33 19 1,000 4,485E-03 0,0267238 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,485E-03 0,02665878 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 4,485E-03 0,02659407 ! cerebral cortex development GO:0021987 40 19 1,000 4,485E-03 0,02652968 ! neuromuscular junction development GO:0007528 43 19 1,000 4,485E-03 0,0264656 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 4,485E-03 0,02640183 ! cellular pigmentation GO:0033059 37 19 1,000 4,485E-03 0,02633836 ! regulation of mitosis GO:0007088 112 63 2,000 4,581E-03 0,02683836 GO:0051783|regulation of nuclear division, ! positive regulation of ossification GO:0045778 50 20 1,000 4,966E-03 0,02902393 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 4,966E-03 0,02895466 ! protein amino acid acetylation GO:0006473 41 20 1,000 4,966E-03 0,02888572 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 4,966E-03 0,02881711 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 4,966E-03 0,02874883 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 4,966E-03 0,02868086 ! actin filament bundle formation GO:0051017 47 20 1,000 4,966E-03 0,02861322 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 4,966E-03 0,02854589 ! negative regulation of T cell activation GO:0050868 41 20 1,000 4,966E-03 0,02847888 ! ear development GO:0043583 114 66 2,000 5,218E-03 0,02985519 ! myeloid cell differentiation GO:0030099 126 67 2,000 5,442E-03 0,03106179 ! lipid phosphorylation GO:0046834 43 21 1,000 5,47E-03 0,03114832 ! ovarian follicle development GO:0001541 39 21 1,000 5,47E-03 0,03107588 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 5,47E-03 0,03100378 ! diencephalon development GO:0021536 36 21 1,000 5,47E-03 0,03093201 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 5,47E-03 0,03086057 ! lung development GO:0030324 165 69 2,000 5,906E-03 0,03324588 ! homeostasis of number of cells GO:0048872 131 69 2,000 5,906E-03 0,03316946 ! positive regulation of bone remodeling GO:0046852 54 22 1,000 5,996E-03 0,03359637 GO:0034105|positive regulation of tissue remodeling, ! hindlimb morphogenesis GO:0035137 47 22 1,000 5,996E-03 0,03351949 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 5,996E-03 0,03344296 ! cellular response to starvation GO:0009267 37 22 1,000 5,996E-03 0,03336679 ! vacuolar transport GO:0007034 41 22 1,000 5,996E-03 0,03329095 ! apoptotic nuclear changes GO:0030262 34 22 1,000 5,996E-03 0,03321546 ! ureteric bud development GO:0001657 50 22 1,000 5,996E-03 0,03314031 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 5,996E-03 0,0330655 ! renal system process GO:0003014 42 22 1,000 5,996E-03 0,03299103 ! vasodilation GO:0042311 40 22 1,000 5,996E-03 0,0329169 ! peptidyl-serine modification GO:0018209 50 22 1,000 5,996E-03 0,03284309 ! positive regulation of B cell activation GO:0050871 42 22 1,000 5,996E-03 0,03276962 ! response to cytokine stimulus GO:0034097 69 22 1,000 5,996E-03 0,03269647 ! activation of JUN kinase activity GO:0007257 47 22 1,000 5,996E-03 0,03262365 ! gut development GO:0048565 44 22 1,000 5,996E-03 0,03255115 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 5,996E-03 0,03247898 ! positive regulation of DNA replication GO:0045740 44 23 1,000 6,544E-03 0,03537072 ! regeneration GO:0031099 42 23 1,000 6,544E-03 0,03529264 ! response to ethanol GO:0045471 47 23 1,000 6,544E-03 0,0352149 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 6,544E-03 0,03513751 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 1,000 6,544E-03 0,03506045 ! fatty acid transport GO:0015908 47 23 1,000 6,544E-03 0,03498373 ! regulation of bone mineralization GO:0030500 54 23 1,000 6,544E-03 0,03490735 ! respiratory tube development GO:0030323 171 72 2,000 6,646E-03 0,03537197 ! actin filament organization GO:0007015 167 72 2,000 6,646E-03 0,03529508 ! B cell activation GO:0042113 179 72 2,000 6,646E-03 0,03521851 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 6,646E-03 0,03514228 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 7,114E-03 0,03753924 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 7,114E-03 0,03745834 ! sex determination GO:0007530 48 24 1,000 7,114E-03 0,03737778 ! regulation of viral reproduction GO:0050792 41 24 1,000 7,114E-03 0,03729757 ! pallium development GO:0021543 56 24 1,000 7,114E-03 0,03721771 ! oogenesis GO:0048477 44 24 1,000 7,114E-03 0,03713818 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 7,114E-03 0,037059 ! platelet activation GO:0030168 41 24 1,000 7,114E-03 0,03698015 ! regulation of caspase activity GO:0043281 136 74 2,000 7,168E-03 0,03718007 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 7,168E-03 0,0371013 ! respiratory system development GO:0060541 175 74 2,000 7,168E-03 0,03702286 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 7,706E-03 0,03971884 ! myeloid leukocyte differentiation GO:0002573 46 25 1,000 7,706E-03 0,03963522 ! regulation of transmembrane transport GO:0034762 39 25 1,000 7,706E-03 0,03955195 ! vasculogenesis GO:0001570 49 25 1,000 7,706E-03 0,03946904 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 7,706E-03 0,03938647 ! negative regulation of DNA replication GO:0008156 45 25 1,000 7,706E-03 0,03930424 ! receptor metabolic process GO:0043112 53 25 1,000 7,706E-03 0,03922236 ! interaction with host GO:0051701 66 25 1,000 7,706E-03 0,03914081 ! lymphocyte proliferation GO:0046651 55 25 1,000 7,706E-03 0,03905961 ! regulation of biomineral formation GO:0070167 56 25 1,000 7,706E-03 0,03897874 ! leukocyte homeostasis GO:0001776 50 25 1,000 7,706E-03 0,0388982 ! liver development GO:0001889 55 25 1,000 7,706E-03 0,038818 ! cell-matrix adhesion GO:0007160 181 76 2,000 7,714E-03 0,03877726 ! regulation of blood pressure GO:0008217 134 76 2,000 7,714E-03 0,03869764 ! lymphocyte differentiation GO:0030098 193 76 2,000 7,714E-03 0,03861834 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 7,996E-03 0,03994805 ! molting cycle process GO:0022404 52 26 1,000 8,32E-03 0,04147991 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 8,32E-03 0,04139543 ! multicellular organismal response to stress GO:0033555 61 26 1,000 8,32E-03 0,04131129 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 8,32E-03 0,0412275 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 8,32E-03 0,04114404 ! negative regulation of cell development GO:0010721 83 26 1,000 8,32E-03 0,04106092 GO:0050768|negative regulation of neurogenesis, ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 8,32E-03 0,04097814 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 8,32E-03 0,04089569 ! neural tube closure GO:0001843 58 26 1,000 8,32E-03 0,04081357 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 8,32E-03 0,04073178 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 8,578E-03 0,0419128 ! tube lumen formation GO:0035148 59 27 1,000 8,954E-03 0,04366339 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 8,954E-03 0,04357641 ! response to starvation GO:0042594 47 27 1,000 8,954E-03 0,04348978 ! cellular response to nutrient levels GO:0031669 45 27 1,000 8,954E-03 0,04340349 ! leukocyte proliferation GO:0070661 59 27 1,000 8,954E-03 0,04331754 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 8,954E-03 0,04323193 ! regulation of peptidase activity GO:0052547 150 82 2,000 9,497E-03 0,04576006 ! protein amino acid acylation GO:0043543 59 28 1,000 9,61E-03 0,04621408 ! base-excision repair GO:0006284 41 28 1,000 9,61E-03 0,04612328 ! regulation of systemic arterial blood pressure GO:0003073 55 28 1,000 9,61E-03 0,04603285 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 9,61E-03 0,04594276 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 9,61E-03 0,04585303 ! exocytosis GO:0006887 153 83 2,000 9,815E-03 0,04674121 ! T cell activation GO:0042110 189 84 2,000 0,01013966 0,04819296 ! response to nutrient GO:0007584 135 84 2,000 0,01013966 0,04809938 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 0,01028603 0,04869915 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01028603 0,04860495 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 1,000 0,01028603 0,04851112 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 0,01028603 0,04841765 ! primary neural tube formation GO:0014020 61 29 1,000 0,01028603 0,04832454 ! response to organic cyclic substance GO:0014070 58 29 1,000 0,01028603 0,04823178 ! somitogenesis GO:0001756 52 29 1,000 0,01028603 0,04813939 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 0,01028603 0,04804734 ! regulation of neuron differentiation GO:0045664 187 85 2,000 0,01047041 0,04881531 ! sterol biosynthetic process GO:0016126 56 30 1,000 0,01098273 0,0511063 ! regulation of B cell activation GO:0050864 55 30 1,000 0,01098273 0,05100914 ! amine biosynthetic process GO:0009309 146 88 2,000 0,01149999 0,05331018 ! ovulation cycle process GO:0022602 55 31 1,000 0,01169968 0,05413319 ! male gonad development GO:0008584 56 31 1,000 0,01169968 0,05403086 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01169968 0,05392891 ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01169968 0,05382735 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01169968 0,05372617 ! response to heat GO:0009408 54 31 1,000 0,01169968 0,05362537 ! positive regulation of protein modification process GO:0031401 156 90 2,000 0,01221764 0,05589454 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01221764 0,05579007 ! spindle organization GO:0007051 50 32 1,000 0,01243665 0,05668422 ! metanephros development GO:0001656 81 32 1,000 0,01243665 0,05657867 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01243665 0,0564735 ! ovulation cycle GO:0042698 57 32 1,000 0,01243665 0,05636873 ! hindbrain development GO:0030902 65 32 1,000 0,01243665 0,05626434 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,01243665 0,05616034 ! regulation of pH GO:0006885 56 33 1,000 0,01319341 0,05946773 ! negative regulation of response to external stimulus GO:0032102 50 33 1,000 0,01319341 0,05935821 ! cholesterol homeostasis GO:0042632 60 33 1,000 0,01319341 0,0592491 GO:0055092|sterol homeostasis, ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01319341 0,05914038 ! regulation of axonogenesis GO:0050770 86 33 1,000 0,01319341 0,05903207 ! regulation of calcium ion transport GO:0051924 60 33 1,000 0,01319341 0,05892415 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 0,01334136 0,05947618 ! response to hydrogen peroxide GO:0042542 56 34 1,000 0,01396974 0,06216405 ! glial cell differentiation GO:0010001 67 34 1,000 0,01396974 0,06205102 ! post-embryonic development GO:0009791 76 34 1,000 0,01396974 0,06193841 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01396974 0,0618262 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,01476539 0,06522939 ! telencephalon development GO:0021537 81 35 1,000 0,01476539 0,06511165 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01476539 0,06499433 ! forebrain development GO:0030900 210 98 2,000 0,0153412 0,06740746 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01558016 0,06833452 ! positive regulation of cell development GO:0010720 85 36 1,000 0,01558016 0,06821206 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01558016 0,06809004 ! cytokine production GO:0001816 68 36 1,000 0,01558016 0,06796845 ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,01641382 0,07147764 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01641382 0,07135045 ! female gonad development GO:0008585 71 37 1,000 0,01641382 0,07122372 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01641382 0,07109744 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01726614 0,07465697 ! regulation of protein stability GO:0031647 77 38 1,000 0,01726614 0,07452507 ! pigment metabolic process GO:0042440 87 38 1,000 0,01726614 0,07439363 ! neural tube formation GO:0001841 79 38 1,000 0,01726614 0,07426265 ! regulation of neuron projection development GO:0010975 102 39 1,000 0,01813692 0,07787081 ! regulation of metal ion transport GO:0010959 71 39 1,000 0,01813692 0,0777342 ! negative regulation of binding GO:0051100 71 39 1,000 0,01813692 0,07759806 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01813692 0,0774624 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01813692 0,07732721 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01813692 0,0771925 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,01813692 0,07705825 ! mammary gland development GO:0030879 93 40 1,000 0,01902593 0,08069504 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01902593 0,08055519 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 0,01902593 0,08041582 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01993296 0,08410399 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,01993296 0,08395899 ! ear morphogenesis GO:0042471 64 42 1,000 0,02085779 0,08770324 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,02085779 0,08755254 ! regulation of protein secretion GO:0050708 77 42 1,000 0,02085779 0,08740237 ! cytokinesis GO:0000910 84 42 1,000 0,02085779 0,0872527 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,02085779 0,08710355 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02180022 0,09088383 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02180022 0,09072901 ! regulation of tube size GO:0035150 76 43 1,000 0,02180022 0,09057471 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 1,000 0,02180022 0,09042093 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02180022 0,09026767 ! monocarboxylic acid transport GO:0015718 93 43 1,000 0,02180022 0,09011494 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,02180022 0,08996271 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,02180022 0,08981101 ! segmentation GO:0035282 78 43 1,000 0,02180022 0,08965981 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,02276003 0,09344999 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 0,02276003 0,09329319 ! hexose transport GO:0008645 68 44 1,000 0,02276003 0,09313692 GO:0015749|monosaccharide transport, ! receptor-mediated endocytosis GO:0006898 98 45 1,000 0,02373701 0,09697244 ! female gamete generation GO:0007292 71 45 1,000 0,02373701 0,09681055 ! polyol metabolic process GO:0019751 77 45 1,000 0,02373701 0,09664919 ! developmental growth GO:0048589 88 45 1,000 0,02373701 0,09648838 ! activation of adenylate cyclase activity GO:0007190 94 46 1,000 0,02473096 0,10036171 ! glycolysis GO:0006096 71 46 1,000 0,02473096 0,10019527 ! neural tube development GO:0021915 91 47 1,000 0,02574168 0,10411744 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,02574168 0,10394534 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02616927 0,10549757 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02616927 0,10532376 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02616927 0,10515053 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02616927 0,10497787 ! neuron fate determination GO:0048664 7 5 0,000 0,02616927 0,10480578 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02616927 0,10463425 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02616927 0,10446328 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02616927 0,10429286 ! polyol transport GO:0015791 12 5 0,000 0,02616927 0,104123 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02616927 0,1039537 ! response to superoxide GO:0000303 10 5 0,000 0,02616927 0,10378494 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02616927 0,10361673 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02616927 0,10344907 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02616927 0,10328195 ! female meiosis GO:0007143 10 5 0,000 0,02616927 0,10311536 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02616927 0,10294932 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02616927 0,1027838 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02616927 0,10261882 ! cobalt ion transport GO:0006824 11 5 0,000 0,02616927 0,10245437 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02616927 0,10229044 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02616927 0,10212704 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02616927 0,10196415 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02616927 0,10180179 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02616927 0,10163994 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02616927 0,10147861 GO:0006451|translational readthrough, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02616927 0,10131779 ! transposition GO:0032196 9 5 0,000 0,02616927 0,10115748 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02616927 0,10099767 ! negative chemotaxis GO:0050919 16 5 0,000 0,02616927 0,10083837 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02616927 0,10067957 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02616927 0,10052127 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02616927 0,10036346 ! behavioral response to pain GO:0048266 10 5 0,000 0,02616927 0,10020615 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02616927 0,10004933 ! Notch receptor processing GO:0007220 11 5 0,000 0,02616927 0,09989301 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02616927 0,09973717 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02616927 0,09958181 ! micturition GO:0060073 9 5 0,000 0,02616927 0,09942694 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02616927 0,09927255 ! copulation GO:0007620 9 5 0,000 0,02616927 0,09911864 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02616927 0,09896521 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02616927 0,09881225 ! bioluminescence GO:0008218 9 5 0,000 0,02616927 0,09865976 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02616927 0,09850774 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02616927 0,09835619 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02616927 0,09820511 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02616927 0,09805449 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02616927 0,09790433 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02616927 0,09775463 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02616927 0,09760538 ! grooming behavior GO:0007625 6 5 0,000 0,02616927 0,09745659 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02616927 0,09730826 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02616927 0,09716037 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02616927 0,09701294 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02616927 0,09686595 ! response to protozoan GO:0001562 13 5 0,000 0,02616927 0,0967194 ! lymph vessel development GO:0001945 10 5 0,000 0,02616927 0,0965733 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02616927 0,09642764 ! endochondral ossification GO:0001958 17 5 0,000 0,02616927 0,09628242 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02616927 0,09613763 ! single strand break repair GO:0000012 8 5 0,000 0,02616927 0,09599328 ! parathyroid gland development GO:0060017 14 5 0,000 0,02616927 0,09584936 ! anagen GO:0042640 7 5 0,000 0,02616927 0,09570588 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02616927 0,09556282 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02616927 0,09542019 ! cytokine secretion GO:0050663 15 5 0,000 0,02616927 0,09527798 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02616927 0,0951362 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02616927 0,09499484 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02616927 0,09485389 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02616927 0,09471337 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02616927 0,09457326 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02616927 0,09443357 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02616927 0,09429428 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02616927 0,09415541 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02616927 0,09401695 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02616927 0,09387889 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02616927 0,09374124 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02616927 0,09360399 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02616927 0,09346714 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02616927 0,09333069 ! valine metabolic process GO:0006573 12 5 0,000 0,02616927 0,09319464 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02616927 0,09305899 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02616927 0,09292373 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02616927 0,09278886 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02616927 0,09265438 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02616927 0,0925203 ! polyol catabolic process GO:0046174 9 5 0,000 0,02616927 0,0923866 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02616927 0,09225328 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02616927 0,09212035 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02616927 0,09198781 ! mitochondrial fission GO:0000266 8 5 0,000 0,02616927 0,09185564 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02616927 0,09172385 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02616927 0,09159244 ! mRNA transcription GO:0009299 10 5 0,000 0,02616927 0,09146141 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02616927 0,09133075 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02616927 0,09120046 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02616927 0,09107055 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02616927 0,090941 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02616927 0,09081183 ! monocyte activation GO:0042117 10 5 0,000 0,02616927 0,09068301 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02616927 0,09055457 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02616927 0,09042649 ! response to food GO:0032094 6 5 0,000 0,02616927 0,09029876 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02616927 0,0901714 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02616927 0,0900444 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02616927 0,08991776 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02616927 0,08979147 ! forebrain neuron development GO:0021884 13 5 0,000 0,02616927 0,08966553 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02616927 0,08953995 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02616927 0,08941472 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02616927 0,08928984 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02616927 0,08916531 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02616927 0,08904112 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02616927 0,08891728 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02616927 0,08879378 ! lipid glycosylation GO:0030259 7 5 0,000 0,02616927 0,08867063 ! nucleobase transport GO:0015851 6 5 0,000 0,02616927 0,08854782 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02616927 0,08842535 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02616927 0,08830321 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02616927 0,08818141 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02616927 0,08805995 ! basic amino acid transport GO:0015802 12 5 0,000 0,02616927 0,08793882 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02616927 0,08781803 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02616927 0,08769757 ! actin nucleation GO:0045010 11 5 0,000 0,02616927 0,08757743 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02616927 0,08745763 ! depurination GO:0045007 5 5 0,000 0,02616927 0,08733815 ! depyrimidination GO:0045008 10 5 0,000 0,02616927 0,087219 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02616927 0,08710017 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02616927 0,08698167 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02616927 0,08686349 GO:0031572|G2/M transition DNA damage checkpoint, ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02616927 0,08674562 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02616927 0,08662808 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02616927 0,08651086 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02616927 0,08639395 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02616927 0,08627736 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02616927 0,08616108 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02616927 0,08604512 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02616927 0,08592947 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02616927 0,08581413 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02616927 0,0856991 ! response to arsenic GO:0046685 11 5 0,000 0,02616927 0,08558437 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02616927 0,08546995 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02616927 0,08535584 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02616927 0,08524203 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02616927 0,08512853 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02616927 0,08501533 ! response to mercury ion GO:0046689 8 5 0,000 0,02616927 0,08490242 ! response to cadmium ion GO:0046686 7 5 0,000 0,02616927 0,08478982 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02616927 0,08467752 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02616927 0,08456551 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02616927 0,0844538 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02616927 0,08434238 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02616927 0,08423126 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02616927 0,08412043 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02616927 0,08400989 ! decidualization GO:0046697 11 5 0,000 0,02616927 0,08389964 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02616927 0,08378968 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02616927 0,08368001 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02616927 0,08357062 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02616927 0,08346152 ! embryonic cleavage GO:0040016 6 5 0,000 0,02616927 0,08335271 ! peroxisome fission GO:0016559 5 5 0,000 0,02616927 0,08324417 ! histone demethylation GO:0016577 13 5 0,000 0,02616927 0,08313592 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02616927 0,08302795 ! mitotic recombination GO:0006312 9 5 0,000 0,02616927 0,08292027 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02616927 0,08281286 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02616927 0,08270572 ! metaphase plate congression GO:0051310 7 5 0,000 0,02616927 0,08259887 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02616927 0,08249229 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02616927 0,08238599 ! enteric nervous system development GO:0048484 8 5 0,000 0,02616927 0,08227996 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02616927 0,0821742 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02616927 0,08206871 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02616927 0,08196349 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02616927 0,08185855 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02616927 0,08175387 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02616927 0,08164946 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02616927 0,08154531 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02616927 0,08144143 ! metaphase GO:0051323 11 5 0,000 0,02616927 0,08133782 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02616927 0,08123447 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02616927 0,08113138 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02616927 0,08102855 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02616927 0,08092598 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02616927 0,08082367 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02616927 0,08072162 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02616927 0,08061983 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02616927 0,08051829 ! response to redox state GO:0051775 6 5 0,000 0,02616927 0,08041701 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02616927 0,08031599 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02616927 0,08021521 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02616927 0,08011469 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02616927 0,08001442 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02616927 0,07991441 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02616927 0,07981464 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02616927 0,07971512 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02616927 0,07961585 ! striatum development GO:0021756 14 5 0,000 0,02616927 0,07951682 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02616927 0,07941804 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02616927 0,07931951 ! glial cell migration GO:0008347 10 5 0,000 0,02616927 0,07922122 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02616927 0,07912317 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02616927 0,07902537 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02616927 0,07892781 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02616927 0,07883049 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02616927 0,07873341 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02616927 0,07863656 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02616927 0,07853996 ! neuroprotection GO:0043526 8 5 0,000 0,02616927 0,07844359 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02616927 0,07834746 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02616927 0,07825156 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02616927 0,0781559 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02616927 0,07806047 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02616927 0,07796527 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02616927 0,07787031 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02616927 0,07777558 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02616927 0,07768108 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02616927 0,0775868 ! spindle assembly GO:0051225 6 5 0,000 0,02616927 0,07749276 ! protein palmitoylation GO:0018345 12 5 0,000 0,02616927 0,07739894 ! drug metabolic process GO:0017144 7 5 0,000 0,02616927 0,07730535 ! stem cell division GO:0017145 11 5 0,000 0,02616927 0,07721199 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02616927 0,07711885 ! organ regeneration GO:0031100 7 5 0,000 0,02616927 0,07702593 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02616927 0,07693324 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02616927 0,07684078 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 1,000 0,02676896 0,07850729 ! cellular component disassembly GO:0022411 89 48 1,000 0,02676896 0,07841316 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,02676896 0,07831925 ! endosome transport GO:0016197 127 48 1,000 0,02676896 0,07822557 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02676896 0,07813211 ! male sex differentiation GO:0046661 93 48 1,000 0,02676896 0,07803887 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,0278126 0,08098472 ! positive regulation of cyclase activity GO:0031281 106 49 1,000 0,0278126 0,08088831 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,0278126 0,08079213 ! JNK cascade GO:0007254 106 49 1,000 0,0278126 0,08069618 ! protein homooligomerization GO:0051260 84 49 1,000 0,0278126 0,08060045 ! regulation of ion transport GO:0043269 86 50 1,000 0,0288724 0,08357259 ! positive regulation of lyase activity GO:0051349 107 50 1,000 0,0288724 0,08347369 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,02994816 0,0864815 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,02994816 0,0863794 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02994816 0,08627754 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02994816 0,08617591 ! positive regulation of binding GO:0051099 88 52 1,000 0,03103968 0,0892117 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,03103968 0,08910687 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,03103968 0,08900228 ! histone modification GO:0016570 104 52 1,000 0,03103968 0,08889794 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0313208 0,08959802 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0313208 0,08949323 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,0313208 0,08938868 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,0313208 0,08928438 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0313208 0,08918031 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,0313208 0,0890765 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,0313208 0,08897292 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0313208 0,08886958 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,0313208 0,08876648 ! response to oxygen radical GO:0000305 11 6 0,000 0,0313208 0,08866363 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,0313208 0,08856101 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,0313208 0,08845862 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,0313208 0,08835648 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0313208 0,08825457 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0313208 0,08815289 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,0313208 0,08805145 ! forebrain regionalization GO:0021871 9 6 0,000 0,0313208 0,08795024 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0313208 0,08784926 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0313208 0,08774852 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,0313208 0,08764801 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0313208 0,08754772 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,0313208 0,08744767 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,0313208 0,08734784 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0313208 0,08724824 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,0313208 0,08714887 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,0313208 0,08704973 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0313208 0,08695081 ! malate metabolic process GO:0006108 13 6 0,000 0,0313208 0,08685211 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,0313208 0,08675364 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,0313208 0,08665539 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,0313208 0,08655736 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,0313208 0,08645956 ! protein refolding GO:0042026 15 6 0,000 0,0313208 0,08636197 ! opsonization GO:0008228 8 6 0,000 0,0313208 0,08626461 ! mating behavior GO:0007617 7 6 0,000 0,0313208 0,08616747 ! erythrocyte maturation GO:0043249 8 6 0,000 0,0313208 0,08607054 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,0313208 0,08597383 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,0313208 0,08587734 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,0313208 0,08578106 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,0313208 0,08568501 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0313208 0,08558916 ! response to interferon-gamma GO:0034341 16 6 0,000 0,0313208 0,08549353 ! toxin metabolic process GO:0009404 11 6 0,000 0,0313208 0,08539811 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0313208 0,08530291 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,0313208 0,08520792 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,0313208 0,08511314 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,0313208 0,08501857 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,0313208 0,08492421 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,0313208 0,08483005 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,0313208 0,08473611 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,0313208 0,08464238 ! thymic T cell selection GO:0045061 16 6 0,000 0,0313208 0,08454885 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,0313208 0,08445553 ! protein lipoylation GO:0009249 10 6 0,000 0,0313208 0,08436241 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,0313208 0,0842695 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,0313208 0,0841768 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0313208 0,0840843 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,0313208 0,083992 ! glutamate catabolic process GO:0006538 12 6 0,000 0,0313208 0,0838999 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,0313208 0,08380801 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0313208 0,08371631 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,0313208 0,08362482 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0313208 0,08353353 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,0313208 0,08344243 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,0313208 0,08335154 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0313208 0,08326084 ! urea metabolic process GO:0019627 7 6 0,000 0,0313208 0,08317034 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0313208 0,08308003 ! neutrophil activation GO:0042119 7 6 0,000 0,0313208 0,08298992 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0313208 0,08290001 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,0313208 0,08281029 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0313208 0,08272077 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,0313208 0,08263144 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0313208 0,0825423 ! neuron apoptosis GO:0051402 15 6 0,000 0,0313208 0,08245335 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0313208 0,0823646 ! T cell mediated immunity GO:0002456 17 6 0,000 0,0313208 0,08227603 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0313208 0,08218766 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,0313208 0,08209947 ! carnitine transport GO:0015879 10 6 0,000 0,0313208 0,08201148 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0313208 0,08192367 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,0313208 0,08183605 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,0313208 0,08174862 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,0313208 0,08166138 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,0313208 0,08157432 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0313208 0,08148744 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,0313208 0,08140075 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,0313208 0,08131425 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,0313208 0,08122793 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,0313208 0,08114179 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0313208 0,08105584 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,0313208 0,08097006 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,0313208 0,08088447 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0313208 0,08079906 ! interaction with symbiont GO:0051702 14 6 0,000 0,0313208 0,08071383 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0313208 0,08062878 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,0313208 0,0805439 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,0313208 0,08045921 ! response to copper ion GO:0046688 10 6 0,000 0,0313208 0,08037469 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,0313208 0,08029036 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0313208 0,08020619 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,0313208 0,08012221 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0313208 0,0800384 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,0313208 0,07995476 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0313208 0,0798713 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,0313208 0,07978802 ! hair follicle maturation GO:0048820 8 6 0,000 0,0313208 0,07970491 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0313208 0,07962197 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,0313208 0,0795392 ! response to pheromone GO:0019236 6 6 0,000 0,0313208 0,0794566 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,0313208 0,07937418 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,0313208 0,07929193 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,0313208 0,07920984 ! subpallium development GO:0021544 15 6 0,000 0,0313208 0,07912793 ! neural tube patterning GO:0021532 8 6 0,000 0,0313208 0,07904619 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,0313208 0,07896461 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0313208 0,07888321 ! G2 phase GO:0051319 16 6 0,000 0,0313208 0,07880197 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,0313208 0,07872089 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,0313208 0,07863999 ! oxygen homeostasis GO:0032364 10 6 0,000 0,0313208 0,07855925 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0313208 0,07847868 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,0313208 0,07839827 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0313208 0,07831802 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,0313208 0,07823794 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0313208 0,07815803 ! receptor internalization GO:0031623 11 6 0,000 0,0313208 0,07807828 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,0313208 0,07799868 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,0313208 0,07791926 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,0313208 0,07783999 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0313208 0,07776088 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,0313208 0,07768194 ! protein deubiquitination GO:0016579 16 6 0,000 0,0313208 0,07760315 ! protein destabilization GO:0031648 9 6 0,000 0,0313208 0,07752453 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,0313208 0,07744606 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,0313208 0,07736775 ! regulation of viral transcription GO:0046782 11 6 0,000 0,0313208 0,07728961 ! progesterone metabolic process GO:0042448 12 6 0,000 0,0313208 0,07721161 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,0313208 0,07713378 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,0313208 0,0770561 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,0313208 0,07697858 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0313208 0,07690122 ! determination of adult lifespan GO:0008340 17 6 0,000 0,0313208 0,07682401 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,0313208 0,07674695 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0313208 0,07667005 ! neural plate development GO:0001840 9 6 0,000 0,0313208 0,0765933 ! catecholamine transport GO:0051937 9 6 0,000 0,0313208 0,07651671 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,0313208 0,07644027 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0313208 0,07636398 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,0313208 0,07628785 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,0313208 0,07621186 ! maternal placenta development GO:0001893 12 6 0,000 0,0313208 0,07613603 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,0313208 0,07606035 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,0313208 0,07598482 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,0313208 0,07590943 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,0313208 0,0758342 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,0313208 0,07575912 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,0313208 0,07568418 GO:0055081|anion homeostasis, ! vesicle organization GO:0016050 127 53 1,000 0,03214678 0,07760334 ! synapse organization GO:0050808 102 53 1,000 0,03214678 0,07752673 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03326925 0,08015461 GO:0010863|positive regulation of phospholipase C activity, ! covalent chromatin modification GO:0016569 115 54 1,000 0,03326925 0,08007564 ! regulation of cell shape GO:0008360 142 54 1,000 0,03326925 0,07999683 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03440691 0,082651 ! cell maturation GO:0048469 107 55 1,000 0,03440691 0,08256981 ! glucose catabolic process GO:0006007 88 56 1,000 0,03555956 0,0852522 ! tRNA transcription GO:0009304 17 7 0,000 0,03644522 0,08728987 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03644522 0,08720438 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03644522 0,08711905 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03644522 0,08703389 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03644522 0,0869489 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03644522 0,08686407 ! sleep GO:0030431 16 7 0,000 0,03644522 0,08677941 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03644522 0,08669491 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03644522 0,08661058 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03644522 0,08652641 ! prostate gland development GO:0030850 14 7 0,000 0,03644522 0,0864424 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03644522 0,08635856 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03644522 0,08627488 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03644522 0,08619136 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03644522 0,086108 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03644522 0,0860248 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03644522 0,08594177 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03644522 0,08585889 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03644522 0,08577618 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03644522 0,08569362 ! glycolipid transport GO:0046836 11 7 0,000 0,03644522 0,08561122 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03644522 0,08552898 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03644522 0,0854469 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03644522 0,08536498 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03644522 0,08528321 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03644522 0,0852016 ! pericardium development GO:0060039 16 7 0,000 0,03644522 0,08512014 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03644522 0,08503885 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03644522 0,0849577 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03644522 0,08487671 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03644522 0,08479588 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03644522 0,0847152 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03644522 0,08463467 ! rhythmic behavior GO:0007622 17 7 0,000 0,03644522 0,08455429 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03644522 0,08447407 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03644522 0,084394 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03644522 0,08431408 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03644522 0,08423432 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03644522 0,0841547 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03644522 0,08407523 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03644522 0,08399592 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03644522 0,08391675 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03644522 0,08383773 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03644522 0,08375886 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03644522 0,08368014 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03644522 0,08360157 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03644522 0,08352314 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03644522 0,08344487 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03644522 0,08336673 ! spinal cord patterning GO:0021511 14 7 0,000 0,03644522 0,08328875 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03644522 0,08321091 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03644522 0,08313321 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03644522 0,08305566 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03644522 0,08297826 ! adrenal gland development GO:0030325 17 7 0,000 0,03644522 0,082901 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03644522 0,08282388 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03644522 0,08274691 ! ovulation GO:0030728 10 7 0,000 0,03644522 0,08267008 ! adenohypophysis development GO:0021984 11 7 0,000 0,03644522 0,08259339 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03644522 0,08251684 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03644522 0,08244044 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03644522 0,08236417 ! microtubule nucleation GO:0007020 21 7 0,000 0,03644522 0,08228805 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03644522 0,08221207 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03644522 0,08213623 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03644522 0,08206053 ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03644522 0,08198496 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03644522 0,08190954 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03644522 0,08183426 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03644522 0,08175911 ! galactose metabolic process GO:0006012 13 7 0,000 0,03644522 0,0816841 ! vesicle fusion GO:0006906 20 7 0,000 0,03644522 0,08160923 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03644522 0,0815345 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03644522 0,0814599 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03644522 0,08138544 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03644522 0,08131112 ! nucleoside transport GO:0015858 11 7 0,000 0,03644522 0,08123693 ! nucleoside salvage GO:0043174 11 7 0,000 0,03644522 0,08116287 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03644522 0,08108895 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03644522 0,08101517 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03644522 0,08094152 ! parturition GO:0007567 16 7 0,000 0,03644522 0,080868 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03644522 0,08079462 ! rRNA modification GO:0000154 14 7 0,000 0,03644522 0,08072137 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03644522 0,08064825 ! spindle checkpoint GO:0031577 16 7 0,000 0,03644522 0,08057527 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03644522 0,08050242 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03644522 0,08042969 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03644522 0,0803571 ! centrosome duplication GO:0051298 14 7 0,000 0,03644522 0,08028464 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03644522 0,08021232 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03644522 0,08014012 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03644522 0,08006805 ! eating behavior GO:0042755 8 7 0,000 0,03644522 0,07999611 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03644522 0,0799243 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03644522 0,07985262 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03644522 0,07978107 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03644522 0,07970964 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03644522 0,07963835 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03644522 0,07956718 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03644522 0,07949614 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03644522 0,07942522 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03644522 0,07935443 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03644522 0,07928377 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03644522 0,07921323 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03644522 0,07914282 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03644522 0,07907253 ! histone ubiquitination GO:0016574 9 7 0,000 0,03644522 0,07900237 ! regulation of meiosis GO:0040020 12 7 0,000 0,03644522 0,07893233 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03644522 0,07886242 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03644522 0,07879263 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03644522 0,07872296 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03644522 0,07865342 ! transcription termination GO:0006353 14 7 0,000 0,03644522 0,078584 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03644522 0,0785147 ! anaphase GO:0051322 18 7 0,000 0,03644522 0,07844553 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03644522 0,07837647 ! axonal fasciculation GO:0007413 19 7 0,000 0,03644522 0,07830754 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03644522 0,07823873 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03644522 0,07817004 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03644522 0,07810147 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,03644522 0,07803302 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03644522 0,07796469 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03644522 0,07789648 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03644522 0,07782838 ! antibiotic transport GO:0042891 9 7 0,000 0,03644522 0,07776041 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03644522 0,07769256 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03644522 0,07762482 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03644522 0,0775572 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03644522 0,07748971 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03644522 0,07742232 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03644522 0,07735506 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03644522 0,07728791 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03644522 0,07722088 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03644522 0,07715396 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03644522 0,07708716 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03644522 0,07702048 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03644522 0,07695391 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03644522 0,07688745 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03644522 0,07682111 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03644522 0,07675489 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03644522 0,07668878 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03644522 0,07662278 ! muscle adaptation GO:0043500 13 7 0,000 0,03644522 0,0765569 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03644522 0,07649113 ! retina homeostasis GO:0001895 12 7 0,000 0,03644522 0,07642547 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03644522 0,07635992 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03644522 0,07629449 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03644522 0,07622917 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03644522 0,07616396 ! heart morphogenesis GO:0003007 105 57 1,000 0,03672701 0,07668726 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,03672701 0,07662177 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03672701 0,07655639 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,03790909 0,07895303 ! nuclear export GO:0051168 110 59 1,000 0,0391056 0,08137562 ! establishment of organelle localization GO:0051656 122 59 1,000 0,0391056 0,08130637 ! lipid modification GO:0030258 112 60 1,000 0,04031636 0,08375244 ! DNA catabolic process GO:0006308 94 60 1,000 0,04031636 0,08368128 ! kidney development GO:0001822 133 60 1,000 0,04031636 0,08361024 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04154268 0,08608037 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04154268 0,08600742 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04154268 0,08593459 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04154268 0,08586189 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04154268 0,08578931 ! male meiosis GO:0007140 9 8 0,000 0,04154268 0,08571686 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04154268 0,08564452 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04154268 0,08557231 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04154268 0,08550022 ! meiotic prophase I GO:0007128 14 8 0,000 0,04154268 0,08542825 ! response to zinc ion GO:0010043 12 8 0,000 0,04154268 0,0853564 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04154268 0,08528467 ! oligopeptide transport GO:0006857 16 8 0,000 0,04154268 0,08521306 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04154268 0,08514157 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04154268 0,08507021 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04154268 0,08499896 ! signal peptide processing GO:0006465 12 8 0,000 0,04154268 0,08492783 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04154268 0,08485682 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04154268 0,08478593 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04154268 0,08471516 ! succinate metabolic process GO:0006105 17 8 0,000 0,04154268 0,0846445 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04154268 0,08457396 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04154268 0,08450354 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04154268 0,08443324 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04154268 0,08436306 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04154268 0,08429299 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04154268 0,08422303 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04154268 0,0841532 ! reflex GO:0060004 17 8 0,000 0,04154268 0,08408348 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04154268 0,08401387 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04154268 0,08394438 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04154268 0,08387501 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04154268 0,08380574 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04154268 0,0837366 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04154268 0,08366757 ! histidine catabolic process GO:0006548 10 8 0,000 0,04154268 0,08359865 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04154268 0,08352984 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04154268 0,08346115 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04154268 0,08339257 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04154268 0,0833241 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04154268 0,08325575 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04154268 0,08318751 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04154268 0,08311937 ! macrophage activation GO:0042116 13 8 0,000 0,04154268 0,08305136 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04154268 0,08298345 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04154268 0,08291565 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04154268 0,08284796 ! purine salvage GO:0043101 12 8 0,000 0,04154268 0,08278039 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04154268 0,08271292 ! osteoblast development GO:0002076 17 8 0,000 0,04154268 0,08264557 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04154268 0,08257832 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04154268 0,08251118 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04154268 0,08244416 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04154268 0,08237724 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04154268 0,08231043 ! intermediate filament organization GO:0045109 12 8 0,000 0,04154268 0,08224372 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04154268 0,08217713 ! cellular extravasation GO:0045123 13 8 0,000 0,04154268 0,08211064 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04154268 0,08204427 ! response to antibiotic GO:0046677 11 8 0,000 0,04154268 0,08197799 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04154268 0,08191183 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04154268 0,08184577 ! DNA topological change GO:0006265 12 8 0,000 0,04154268 0,08177982 ! response to tropane GO:0014073 15 8 0,000 0,04154268 0,08171397 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04154268 0,08164824 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04154268 0,0815826 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04154268 0,08151707 ! mast cell activation GO:0045576 14 8 0,000 0,04154268 0,08145165 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04154268 0,08138633 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04154268 0,08132112 ! gas homeostasis GO:0033483 14 8 0,000 0,04154268 0,08125601 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04154268 0,08119101 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04154268 0,0811261 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04154268 0,08106131 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04154268 0,08099661 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04154268 0,08093202 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04154268 0,08086754 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04154268 0,08080315 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04154268 0,08073887 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04154268 0,08067469 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04154268 0,08061061 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04154268 0,08054663 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04154268 0,08048276 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04154268 0,08041898 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04154268 0,08035531 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04154268 0,08029174 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04154268 0,08022827 ! hormone catabolic process GO:0042447 17 8 0,000 0,04154268 0,08016489 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04154268 0,08010162 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04154268 0,08003845 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04154268 0,07997538 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04154268 0,07991241 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04154268 0,07984953 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04154268 0,07978676 ! adult feeding behavior GO:0008343 10 8 0,000 0,04154268 0,07972408 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04154268 0,0796615 ! ATP catabolic process GO:0006200 11 8 0,000 0,04154268 0,07959902 ! blastocyst growth GO:0001832 19 8 0,000 0,04154268 0,07953664 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04154268 0,07947436 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04154268 0,07941217 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04154268 0,07935008 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04154268 0,07928809 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04154268 0,0792262 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04154268 0,0791644 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04154268 0,07910269 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04154268 0,07904109 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04154268 0,07897958 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04154268 0,07891816 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04154268 0,07885684 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04154268 0,07879562 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04154268 0,07873449 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04154268 0,07867345 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04154268 0,07861251 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04154268 0,07855167 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04154268 0,07849092 ! viral reproductive process GO:0022415 132 62 1,000 0,0427799 0,08076607 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,04403232 0,08306638 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,04657757 0,08780016 ! axon extension GO:0048675 16 9 0,000 0,04661331 0,08779978 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04661331 0,08773213 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04661331 0,0876646 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04661331 0,08759716 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04661331 0,08752983 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04661331 0,0874626 ! reproductive behavior GO:0019098 22 9 0,000 0,04661331 0,08739548 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04661331 0,08732846 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04661331 0,08726154 ! UTP metabolic process GO:0046051 10 9 0,000 0,04661331 0,08719472 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04661331 0,08712801 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04661331 0,0870614 ! artery development GO:0060840 25 9 0,000 0,04661331 0,08699489 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04661331 0,08692848 ! equilibrioception GO:0050957 20 9 0,000 0,04661331 0,08686217 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04661331 0,08679597 ! chemosensory behavior GO:0007635 21 9 0,000 0,04661331 0,08672986 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04661331 0,08666386 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04661331 0,08659795 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04661331 0,08653215 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04661331 0,08646645 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04661331 0,08640084 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04661331 0,08633534 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04661331 0,08626993 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04661331 0,08620463 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04661331 0,08613942 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04661331 0,08607431 ! protein targeting to ER GO:0045047 25 9 0,000 0,04661331 0,0860093 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04661331 0,08594439 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04661331 0,08587957 ! glycine catabolic process GO:0006546 15 9 0,000 0,04661331 0,08581485 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04661331 0,08575023 ! endosome organization GO:0007032 20 9 0,000 0,04661331 0,08568571 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04661331 0,08562129 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04661331 0,08555696 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04661331 0,08549273 ! mannose metabolic process GO:0006013 13 9 0,000 0,04661331 0,08542859 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04661331 0,08536455 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04661331 0,08530061 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04661331 0,08523676 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04661331 0,08517301 ! receptor clustering GO:0043113 20 9 0,000 0,04661331 0,08510935 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04661331 0,08504579 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04661331 0,08498232 ! retinol metabolic process GO:0042572 20 9 0,000 0,04661331 0,08491895 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04661331 0,08485567 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04661331 0,08479249 ! macrophage differentiation GO:0030225 15 9 0,000 0,04661331 0,0847294 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04661331 0,0846664 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04661331 0,0846035 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04661331 0,08454069 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04661331 0,08447798 ! response to amine stimulus GO:0014075 13 9 0,000 0,04661331 0,08441535 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04661331 0,08435282 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04661331 0,08429039 ! erythrocyte development GO:0048821 17 9 0,000 0,04661331 0,08422804 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04661331 0,08416579 ! renal water homeostasis GO:0003091 15 9 0,000 0,04661331 0,08410363 ! postreplication repair GO:0006301 25 9 0,000 0,04661331 0,08404156 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04661331 0,08397958 ! icosanoid secretion GO:0032309 15 9 0,000 0,04661331 0,08391769 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04661331 0,0838559 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04661331 0,08379419 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04661331 0,08373258 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04661331 0,08367106 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04661331 0,08360963 ! sterol catabolic process GO:0016127 14 9 0,000 0,04661331 0,08354828 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04661331 0,08348703 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04661331 0,08342587 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04661331 0,0833648 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04661331 0,08330381 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04661331 0,08324292 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04661331 0,08318211 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04661331 0,08312139 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04661331 0,08306077 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04661331 0,08300023 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04661331 0,08293977 ! purine base metabolic process GO:0006144 25 9 0,000 0,04661331 0,08287941 ! pigment granule transport GO:0051904 17 9 0,000 0,04661331 0,08281913 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04661331 0,08275895 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04661331 0,08269885 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04661331 0,08263883 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04661331 0,08257891 ! mitochondrion localization GO:0051646 18 9 0,000 0,04661331 0,08251907 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,04787005 0,0846825 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,04787005 0,08462122 ! gonad development GO:0008406 115 66 1,000 0,04787005 0,08456004 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,04917553 0,08680334 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 1,000 0,04917553 0,08674067 ! fatty acid biosynthetic process GO:0006633 139 67 1,000 0,04917553 0,08667808 ! secondary metabolic process GO:0019748 125 67 1,000 0,04917553 0,08661559 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,05049385 0,08887354 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,05049385 0,08880955 ! hexose catabolic process GO:0019320 113 68 1,000 0,05049385 0,08874566 ! detection of external stimulus GO:0009581 102 68 1,000 0,05049385 0,08868186 ! viral reproduction GO:0016032 142 68 1,000 0,05049385 0,08861815 ! regulation of lipase activity GO:0060191 137 68 1,000 0,05049385 0,08855454 ! adaptive immune response GO:0002250 126 68 1,000 0,05049385 0,08849101 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,05049385 0,08842758 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05165726 0,0904002 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05165726 0,09033549 ! associative learning GO:0008306 21 10 0,000 0,05165726 0,09027087 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05165726 0,09020634 ! phosphate transport GO:0006817 24 10 0,000 0,05165726 0,09014191 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05165726 0,09007757 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05165726 0,09001332 ! CTP metabolic process GO:0046036 11 10 0,000 0,05165726 0,08994916 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05165726 0,0898851 ! GTP metabolic process GO:0046039 11 10 0,000 0,05165726 0,08982112 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05165726 0,08975724 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05165726 0,08969344 ! social behavior GO:0035176 29 10 0,000 0,05165726 0,08962974 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05165726 0,08956613 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05165726 0,08950261 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05165726 0,08943917 ! androgen metabolic process GO:0008209 17 10 0,000 0,05165726 0,08937583 ! phospholipid efflux GO:0033700 19 10 0,000 0,05165726 0,08931258 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05165726 0,08924942 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05165726 0,08918634 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05165726 0,08912336 ! pathogenesis GO:0009405 17 10 0,000 0,05165726 0,08906046 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05165726 0,08899766 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05165726 0,08893494 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05165726 0,08887231 ! endoderm development GO:0007492 18 10 0,000 0,05165726 0,08880976 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05165726 0,08874731 ! arginine catabolic process GO:0006527 17 10 0,000 0,05165726 0,08868494 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05165726 0,08862267 ! proline metabolic process GO:0006560 13 10 0,000 0,05165726 0,08856047 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05165726 0,08849837 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05165726 0,08843635 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05165726 0,08837442 ! V(D)J recombination GO:0033151 34 10 0,000 0,05165726 0,08831258 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05165726 0,08825082 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05165726 0,08818915 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05165726 0,08812757 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05165726 0,08806607 ! multicellular organism growth GO:0035264 19 10 0,000 0,05165726 0,08800466 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05165726 0,08794333 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05165726 0,08788209 ! ruffle organization GO:0031529 17 10 0,000 0,05165726 0,08782093 ! epithelial cell development GO:0002064 21 10 0,000 0,05165726 0,08775986 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05165726 0,08769887 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05165726 0,08763797 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05165726 0,08757715 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05165726 0,08751642 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05165726 0,08745577 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05165726 0,0873952 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,05165726 0,08733472 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05165726 0,08727433 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05165726 0,08721401 ! segment specification GO:0007379 15 10 0,000 0,05165726 0,08715378 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05165726 0,08709363 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05165726 0,08703357 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05165726 0,08697359 ! response to dsRNA GO:0043331 23 10 0,000 0,05165726 0,08691369 ! DNA ligation GO:0006266 18 10 0,000 0,05165726 0,08685387 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05165726 0,08679414 ! melanosome localization GO:0032400 16 10 0,000 0,05165726 0,08673449 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05165726 0,08667491 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05165726 0,08661543 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05165726 0,08655602 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05165726 0,08649669 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05165726 0,08643745 ! induction of an organ GO:0001759 17 10 0,000 0,05165726 0,08637829 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05165726 0,0863192 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05165726 0,0862602 ! protein sumoylation GO:0016925 17 10 0,000 0,05165726 0,08620128 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05165726 0,08614244 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05165726 0,08608368 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05165726 0,086025 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05165726 0,0859664 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05165726 0,08590788 ! salivary gland development GO:0007431 28 10 0,000 0,05165726 0,08584944 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05165726 0,08579108 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05165726 0,0857328 ! midbrain development GO:0030901 14 10 0,000 0,05165726 0,08567459 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05165726 0,08561647 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05165726 0,08555842 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05165726 0,08550046 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05165726 0,08544257 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05165726 0,08538476 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05165726 0,08532703 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05165726 0,08526938 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05165726 0,0852118 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05165726 0,0851543 ! detection of calcium ion GO:0005513 24 10 0,000 0,05165726 0,08509688 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05165726 0,08503954 ! blastocyst formation GO:0001825 18 10 0,000 0,05165726 0,08498227 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05165726 0,08492508 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05165726 0,08486797 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05165726 0,08481094 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05165726 0,08475398 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05165726 0,0846971 ! urogenital system development GO:0001655 149 69 1,000 0,05182482 0,08491485 ! developmental maturation GO:0021700 128 69 1,000 0,05182482 0,08485794 ! germ cell development GO:0007281 133 70 1,000 0,05316829 0,08699942 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,05452408 0,08915819 ! appendage morphogenesis GO:0035107 150 72 1,000 0,05589203 0,09133394 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,05589203 0,09127289 ! respiratory burst GO:0045730 17 11 0,000 0,05667466 0,09248911 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05667466 0,09242737 ! neuron fate specification GO:0048665 18 11 0,000 0,05667466 0,09236571 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05667466 0,09230413 ! thyroid gland development GO:0030878 26 11 0,000 0,05667466 0,09224263 ! synapsis GO:0007129 14 11 0,000 0,05667466 0,09218122 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05667466 0,09211989 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05667466 0,09205864 ! response to pain GO:0048265 27 11 0,000 0,05667466 0,09199747 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05667466 0,09193638 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,05667466 0,09187538 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05667466 0,09181445 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05667466 0,09175361 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05667466 0,09169284 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05667466 0,09163216 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05667466 0,09157156 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05667466 0,09151103 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05667466 0,09145059 GO:0010833|telomere maintenance via telomere lengthening, ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05667466 0,09139023 ! UV protection GO:0009650 20 11 0,000 0,05667466 0,09132994 ! adult heart development GO:0007512 16 11 0,000 0,05667466 0,09126974 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05667466 0,09120961 ! macroautophagy GO:0016236 19 11 0,000 0,05667466 0,09114957 ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05667466 0,0910896 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05667466 0,09102971 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05667466 0,0909699 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05667466 0,09091017 ! regulation of organ growth GO:0046620 14 11 0,000 0,05667466 0,09085052 ! pigment granule localization GO:0051875 20 11 0,000 0,05667466 0,09079095 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05667466 0,09073145 ! vasoconstriction GO:0042310 20 11 0,000 0,05667466 0,09067203 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05667466 0,09061269 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05667466 0,09055343 ! embryonic axis specification GO:0000578 19 11 0,000 0,05667466 0,09049424 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05667466 0,09043514 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05667466 0,09037611 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05667466 0,09031715 ! DNA methylation GO:0006306 19 11 0,000 0,05667466 0,09025828 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05667466 0,09019947 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05667466 0,09014075 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05667466 0,0900821 ! prophase GO:0051324 17 11 0,000 0,05667466 0,09002353 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05667466 0,08996504 ! nucleosome positioning GO:0016584 15 11 0,000 0,05667466 0,08990662 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05667466 0,08984828 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05667466 0,08979001 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05667466 0,08973182 ! apical protein localization GO:0045176 18 11 0,000 0,05667466 0,0896737 ! acid secretion GO:0046717 20 11 0,000 0,05667466 0,08961566 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05667466 0,08955769 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05667466 0,0894998 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05667466 0,08944199 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05667466 0,08938424 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05667466 0,08932658 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,05667466 0,08926898 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05667466 0,08921147 ! germ cell migration GO:0008354 26 11 0,000 0,05667466 0,08915402 ! embryonic gut development GO:0048566 19 11 0,000 0,05667466 0,08909665 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05667466 0,08903935 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05667466 0,08898213 ! activation of innate immune response GO:0002218 16 11 0,000 0,05667466 0,08892498 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05667466 0,0888679 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05667466 0,0888109 ! lysogeny GO:0030069 22 11 0,000 0,05667466 0,08875397 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05667466 0,08869711 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05667466 0,08864033 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05667466 0,08858362 ! nucleus localization GO:0051647 22 11 0,000 0,05667466 0,08852698 ! appendage development GO:0048736 151 73 1,000 0,05727198 0,08940284 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 1,000 0,05727198 0,08934575 ! organelle localization GO:0051640 155 74 1,000 0,05866375 0,09145855 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,06006719 0,09358683 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,06006719 0,09352718 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,06006719 0,09346761 ! axon guidance GO:0007411 162 75 1,000 0,06006719 0,09340811 ! rhythmic process GO:0048511 142 75 1,000 0,06006719 0,09334869 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06166566 0,0957719 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06166566 0,09571106 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06166566 0,09565029 ! mating GO:0007618 17 12 0,000 0,06166566 0,0955896 ! protein complex disassembly GO:0043241 28 12 0,000 0,06166566 0,09552898 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06166566 0,09546844 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06166566 0,09540798 ! hippocampus development GO:0021766 29 12 0,000 0,06166566 0,0953476 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,06166566 0,09528729 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06166566 0,09522706 ! T cell proliferation GO:0042098 32 12 0,000 0,06166566 0,0951669 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06166566 0,09510682 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06166566 0,09504682 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06166566 0,09498689 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06166566 0,09492703 ! drug transport GO:0015893 16 12 0,000 0,06166566 0,09486726 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06166566 0,09480755 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06166566 0,09474793 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06166566 0,09468837 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06166566 0,0946289 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06166566 0,09456949 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06166566 0,09451017 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06166566 0,09445091 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 21 12 0,000 0,06166566 0,09439173 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06166566 0,09433263 ! entry into host cell GO:0030260 34 12 0,000 0,06166566 0,09427359 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06166566 0,09421464 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06166566 0,09415575 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06166566 0,09409694 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06166566 0,0940382 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06166566 0,09397954 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06166566 0,09392095 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06166566 0,09386243 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06166566 0,09380399 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06166566 0,09374562 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06166566 0,09368732 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06166566 0,09362909 ! cranial nerve development GO:0021545 23 12 0,000 0,06166566 0,09357093 ! fucose catabolic process GO:0019317 25 12 0,000 0,06166566 0,09351285 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06166566 0,09345484 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06166566 0,0933969 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06166566 0,09333904 ! zymogen activation GO:0031638 18 12 0,000 0,06166566 0,09328124 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06166566 0,09322352 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06166566 0,09316587 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06166566 0,09310828 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06166566 0,09305077 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06166566 0,09299334 ! defense response to fungus GO:0050832 15 12 0,000 0,06166566 0,09293597 ! developmental induction GO:0031128 22 12 0,000 0,06166566 0,09287867 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06166566 0,09282144 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06166566 0,09276429 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06166566 0,0927072 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06166566 0,09265019 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,06290843 0,09445931 ! monosaccharide catabolic process GO:0046365 125 77 1,000 0,06290843 0,09440129 ! regulation of catabolic process GO:0009894 173 77 1,000 0,06290843 0,09434334 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06434591 0,09643991 ! steroid biosynthetic process GO:0006694 146 79 1,000 0,06579442 0,09855045 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06663039 0,09974145 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06663039 0,09968037 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06663039 0,09961937 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06663039 0,09955844 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06663039 0,09949758 ! peroxisomal transport GO:0043574 28 13 0,000 0,06663039 0,0994368 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06663039 0,0993761 ! cartilage condensation GO:0001502 22 13 0,000 0,06663039 0,09931546 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06663039 0,09925491 ! organelle fusion GO:0048284 36 13 0,000 0,06663039 0,09919442 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06663039 0,09913401 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06663039 0,09907367 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06663039 0,09901341 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06663039 0,09895322 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06663039 0,0988931 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06663039 0,09883306 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06663039 0,09877309 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06663039 0,09871319 ! methionine metabolic process GO:0006555 31 13 0,000 0,06663039 0,09865336 ! plasma membrane organization GO:0007009 27 13 0,000 0,06663039 0,09859361 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06663039 0,09853393 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06663039 0,09847432 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06663039 0,09841478 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06663039 0,09835531 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,06663039 0,09829592 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06663039 0,0982366 ! exocrine system development GO:0035272 34 13 0,000 0,06663039 0,09817735 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06663039 0,09811817 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06663039 0,09805906 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06663039 0,09800003 ! L-glutamate transport GO:0015813 30 13 0,000 0,06663039 0,09794106 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06663039 0,09788217 ! protein homotetramerization GO:0051289 24 13 0,000 0,06663039 0,09782334 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06663039 0,09776459 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06663039 0,09770591 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06663039 0,0976473 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06663039 0,09758876 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06663039 0,09753028 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06663039 0,09747188 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06663039 0,09741355 ! histone methylation GO:0016571 29 13 0,000 0,06663039 0,09735529 ! chromatin silencing GO:0006342 29 13 0,000 0,06663039 0,0972971 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06663039 0,09723898 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06663039 0,09718092 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06663039 0,09712294 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06663039 0,09706502 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06663039 0,09700718 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06663039 0,0969494 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06663039 0,09689169 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06663039 0,09683405 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06663039 0,09677648 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06663039 0,09671898 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06663039 0,09666155 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06663039 0,09660418 ! insulin secretion GO:0030073 24 13 0,000 0,06663039 0,09654688 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06663039 0,09648965 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06663039 0,09643249 ! acrosome reaction GO:0007340 19 13 0,000 0,06663039 0,0963754 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06663039 0,09631837 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06663039 0,09626141 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,06725381 0,09710465 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,06725381 0,09704729 ! protein import into nucleus GO:0006606 174 82 1,000 0,07020461 0,10124549 ! rRNA transcription GO:0009303 28 14 0,000 0,07156899 0,10315224 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07156899 0,10309142 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07156899 0,10303067 ! water transport GO:0006833 21 14 0,000 0,07156899 0,10296999 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07156899 0,10290939 ! non-recombinational repair GO:0000726 29 14 0,000 0,07156899 0,10284885 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07156899 0,10278839 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07156899 0,102728 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07156899 0,10266767 ! lipid localization GO:0010876 32 14 0,000 0,07156899 0,10260742 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07156899 0,10254724 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07156899 0,10248713 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07156899 0,10242709 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07156899 0,10236713 ! arginine metabolic process GO:0006525 21 14 0,000 0,07156899 0,10230723 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07156899 0,1022474 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07156899 0,10218764 ! regulation of heart rate GO:0002027 25 14 0,000 0,07156899 0,10212795 ! organic alcohol transport GO:0015850 29 14 0,000 0,07156899 0,10206833 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07156899 0,10200878 ! embryo implantation GO:0007566 30 14 0,000 0,07156899 0,1019493 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07156899 0,10188989 ! bone mineralization GO:0030282 18 14 0,000 0,07156899 0,10183055 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07156899 0,10177127 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07156899 0,10171207 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07156899 0,10165294 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07156899 0,10159387 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07156899 0,10153487 ! ribosome assembly GO:0042255 18 14 0,000 0,07156899 0,10147594 ! cerebellum development GO:0021549 23 14 0,000 0,07156899 0,10141708 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07156899 0,10135829 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07156899 0,10129957 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07156899 0,10124091 ! NADP metabolic process GO:0006739 24 14 0,000 0,07156899 0,10118232 ! oxygen transport GO:0015671 22 14 0,000 0,07156899 0,1011238 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07156899 0,10106535 ! male genitalia development GO:0030539 26 14 0,000 0,07156899 0,10100696 ! regulation of axon extension GO:0030516 43 14 0,000 0,07156899 0,10094864 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07156899 0,10089039 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07156899 0,10083221 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,07169571 0,10095252 ! nuclear import GO:0051170 177 83 1,000 0,07169571 0,10089436 ! response to metal ion GO:0010038 158 84 1,000 0,07319708 0,10294787 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,07470856 0,10501324 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,07623002 0,10709024 ! regulation of lyase activity GO:0051339 169 86 1,000 0,07623002 0,1070287 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,07623002 0,10696722 GO:0002696|positive regulation of leukocyte activation, ! lactation GO:0007595 30 15 0,000 0,0764816 0,10725864 ! reproductive cellular process GO:0048610 22 15 0,000 0,0764816 0,10719711 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0764816 0,10713564 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0764816 0,10707424 ! superoxide anion generation GO:0042554 22 15 0,000 0,0764816 0,10701292 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0764816 0,10695166 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0764816 0,10689048 ! copper ion transport GO:0006825 22 15 0,000 0,0764816 0,10682936 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0764816 0,10676832 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0764816 0,10670734 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0764816 0,10664644 ! sulfate transport GO:0008272 27 15 0,000 0,0764816 0,1065856 ! response to cAMP GO:0051591 25 15 0,000 0,0764816 0,10652483 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,0764816 0,10646413 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0764816 0,10640351 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0764816 0,10634295 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0764816 0,10628246 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0764816 0,10622203 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0764816 0,10616168 ! vesicle coating GO:0006901 38 15 0,000 0,0764816 0,10610139 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,0764816 0,10604118 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0764816 0,10598103 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0764816 0,10592095 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0764816 0,10586094 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0764816 0,10580099 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0764816 0,10574112 ! histone deacetylation GO:0016575 24 15 0,000 0,0764816 0,10568131 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0764816 0,10562157 ! water homeostasis GO:0030104 28 15 0,000 0,0764816 0,1055619 ! cofactor transport GO:0051181 30 15 0,000 0,0764816 0,10550229 ! muscle maintenance GO:0046716 26 15 0,000 0,0764816 0,10544275 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0764816 0,10538328 ! intestinal absorption GO:0050892 31 15 0,000 0,0764816 0,10532388 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0764816 0,10526454 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0764816 0,10520527 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0764816 0,10514606 ! cell killing GO:0001906 32 15 0,000 0,0764816 0,10508693 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0764816 0,10502786 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0764816 0,10496885 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0764816 0,10490991 ! actin filament polymerization GO:0030041 27 15 0,000 0,0764816 0,10485104 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0764816 0,10479224 ! alcohol catabolic process GO:0046164 142 87 1,000 0,0777613 0,1064859 ! nucleosome assembly GO:0006334 126 87 1,000 0,0777613 0,10642625 ! chromatin assembly GO:0031497 128 88 1,000 0,07930226 0,10847448 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,08085276 0,11053345 ! regulation of DNA binding GO:0051101 167 89 1,000 0,08085276 0,11047163 ! protein localization in nucleus GO:0034504 192 89 1,000 0,08085276 0,11040988 ! regulation of neurological system process GO:0031644 175 89 1,000 0,08085276 0,1103482 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08136836 0,11098989 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08136836 0,11092795 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08136836 0,11086609 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08136836 0,11080429 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08136836 0,11074256 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,08136836 0,1106809 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08136836 0,11061931 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08136836 0,11055778 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08136836 0,11049633 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08136836 0,11043494 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08136836 0,11037362 ! startle response GO:0001964 28 16 0,000 0,08136836 0,11031237 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08136836 0,11025119 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08136836 0,11019007 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08136836 0,11012903 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08136836 0,11006805 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08136836 0,11000714 ! fructose metabolic process GO:0006000 25 16 0,000 0,08136836 0,10994629 ! L-amino acid transport GO:0015807 33 16 0,000 0,08136836 0,10988551 ! stem cell development GO:0048864 46 16 0,000 0,08136836 0,1098248 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08136836 0,10976416 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08136836 0,10970358 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08136836 0,10964307 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08136836 0,10958263 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08136836 0,10952226 ! axon cargo transport GO:0008088 46 16 0,000 0,08136836 0,10946195 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08136836 0,1094017 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08136836 0,10934153 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,08136836 0,10928142 ! DNA replication initiation GO:0006270 28 16 0,000 0,08136836 0,10922137 ! neuron recognition GO:0008038 40 16 0,000 0,08136836 0,10916139 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08136836 0,10910148 ! tissue regeneration GO:0042246 27 16 0,000 0,08136836 0,10904163 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08136836 0,10898185 ! biomineral formation GO:0031214 22 16 0,000 0,08136836 0,10892213 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08136836 0,10886248 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08136836 0,1088029 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08136836 0,10874338 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08136836 0,10868392 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08136836 0,10862453 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08136836 0,10856521 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08136836 0,10850595 ! peptide hormone processing GO:0016486 27 16 0,000 0,08136836 0,10844675 ! response to inorganic substance GO:0010035 173 90 1,000 0,08241265 0,10977868 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,08398179 0,1118079 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,08398179 0,11174701 ! bone development GO:0060348 206 92 1,000 0,08556004 0,11378507 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,08556004 0,11372316 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08622939 0,11455051 ! signal complex assembly GO:0007172 47 17 0,000 0,08622939 0,11448826 ! filopodium assembly GO:0046847 42 17 0,000 0,08622939 0,11442607 ! endothelial cell migration GO:0043542 31 17 0,000 0,08622939 0,11436395 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08622939 0,1143019 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08622939 0,11423991 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08622939 0,11417799 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08622939 0,11411614 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08622939 0,11405436 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08622939 0,11399264 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08622939 0,11393099 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08622939 0,1138694 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08622939 0,11380789 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08622939 0,11374643 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08622939 0,11368505 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08622939 0,11362373 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08622939 0,11356248 ! membrane budding GO:0006900 42 17 0,000 0,08622939 0,11350129 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08622939 0,11344017 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08622939 0,11337912 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08622939 0,11331813 ! genitalia development GO:0048806 32 17 0,000 0,08622939 0,1132572 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08622939 0,11319634 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08622939 0,11313555 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08622939 0,11307482 ! steroid catabolic process GO:0006706 34 17 0,000 0,08622939 0,11301416 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08622939 0,11295356 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08622939 0,11289303 ! gas transport GO:0015669 26 17 0,000 0,08622939 0,11283256 ! organic cation transport GO:0015695 32 17 0,000 0,08622939 0,11277216 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08622939 0,11271182 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08622939 0,11265155 ! female pregnancy GO:0007565 166 94 1,000 0,08874332 0,11587383 ! sterol metabolic process GO:0016125 166 94 1,000 0,08874332 0,11581193 ! nucleosome organization GO:0034728 143 95 1,000 0,09034807 0,11784322 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,09034807 0,11778033 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,09106483 0,11865141 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09106483 0,11858816 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09106483 0,11852498 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09106483 0,11846187 GO:0050886|endocrine process, ! adult walking behavior GO:0007628 36 18 0,000 0,09106483 0,11839882 ! patterning of blood vessels GO:0001569 43 18 0,000 0,09106483 0,11833585 ! heart looping GO:0001947 34 18 0,000 0,09106483 0,11827293 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09106483 0,11821009 ! centrosome cycle GO:0007098 26 18 0,000 0,09106483 0,11814731 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,09106483 0,1180846 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09106483 0,11802196 ! glycine metabolic process GO:0006544 30 18 0,000 0,09106483 0,11795938 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09106483 0,11789687 ! response to retinoic acid GO:0032526 31 18 0,000 0,09106483 0,11783442 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09106483 0,11777204 ! DNA integration GO:0015074 32 18 0,000 0,09106483 0,11770973 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,09106483 0,11764748 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09106483 0,1175853 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09106483 0,11752319 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09106483 0,11746114 ! neural crest cell migration GO:0001755 41 18 0,000 0,09106483 0,11739915 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09106483 0,11733723 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,09106483 0,11727538 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09106483 0,11721359 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,09106483 0,11715186 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,09106483 0,11709021 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09106483 0,11702861 ! detection of bacterium GO:0016045 22 18 0,000 0,09106483 0,11696708 ! nerve development GO:0021675 34 18 0,000 0,09106483 0,11690562 ! microspike assembly GO:0030035 46 18 0,000 0,09106483 0,11684422 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09106483 0,11678288 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,09106483 0,11672161 ! sex differentiation GO:0007548 171 96 1,000 0,09196139 0,11780896 ! response to protein stimulus GO:0051789 158 96 1,000 0,09196139 0,11774721 ! regulation of T cell activation GO:0050863 175 96 1,000 0,09196139 0,11768553 ! transcription initiation GO:0006352 171 97 1,000 0,09358314 0,11969822 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,09521318 0,12171941 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09587483 0,12250115 ! positive regulation of translation GO:0045727 31 19 0,000 0,09587483 0,12243712 ! neuron maturation GO:0042551 46 19 0,000 0,09587483 0,12237315 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09587483 0,12230924 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09587483 0,12224541 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09587483 0,12218164 ! memory GO:0007613 34 19 0,000 0,09587483 0,12211794 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09587483 0,1220543 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09587483 0,12199073 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09587483 0,12192723 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09587483 0,12186379 ! pigmentation during development GO:0048066 42 19 0,000 0,09587483 0,12180042 ! response to vitamin A GO:0033189 32 19 0,000 0,09587483 0,12173711 ! heme metabolic process GO:0042168 40 19 0,000 0,09587483 0,12167387 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09587483 0,1216107 ! response to fungus GO:0009620 26 19 0,000 0,09587483 0,12154759 ! peptide cross-linking GO:0018149 39 19 0,000 0,09587483 0,12148454 ! protein export from nucleus GO:0006611 40 19 0,000 0,09587483 0,12142157 ! heart process GO:0003015 32 19 0,000 0,09587483 0,12135865 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09587483 0,12129581 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09587483 0,12123302 ! visual learning GO:0008542 38 19 0,000 0,09587483 0,12117031 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09587483 0,12110765 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09587483 0,12104507 ! vitamin transport GO:0051180 31 19 0,000 0,09587483 0,12098254 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09587483 0,12092008 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09587483 0,12085769 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09587483 0,12079536 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09587483 0,12073309 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09587483 0,12067089 ! cilium assembly GO:0042384 38 19 0,000 0,09587483 0,12060876 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09587483 0,12054668 ! protein secretion GO:0009306 45 20 0,000 0,1006595 0,12649751 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,1006595 0,12643247 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,1006595 0,1263675 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,1006595 0,1263026 ! skin development GO:0043588 42 20 0,000 0,1006595 0,12623776 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,1006595 0,12617299 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,1006595 0,12610829 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,1006595 0,12604365 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,1006595 0,12597908 ! response to vitamin GO:0033273 36 20 0,000 0,1006595 0,12591457 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,1006595 0,12585013 ! bile acid metabolic process GO:0008206 34 20 0,000 0,1006595 0,12578576 ! retinoid metabolic process GO:0001523 34 20 0,000 0,1006595 0,12572145 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,1006595 0,12565721 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,1006595 0,12559303 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,1006595 0,12552892 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,1006595 0,12546488 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,1006595 0,1254009 ! peptide secretion GO:0002790 38 20 0,000 0,1006595 0,12533698 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,1006595 0,12527313 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,1006595 0,12520935 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,1006595 0,12514563 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,1006595 0,12508197 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,1006595 0,12501838 ! cell-cell junction organization GO:0045216 43 20 0,000 0,1006595 0,12495486 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,1006595 0,1248914 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,1006595 0,124828 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,1006595 0,12476467 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,1006595 0,1247014 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,1006595 0,1246382 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,1006595 0,12457506 ! regulation of cell killing GO:0031341 46 21 0,000 0,10541899 0,13039928 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10541899 0,13033329 ! hormone secretion GO:0046879 39 21 0,000 0,10541899 0,13026737 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10541899 0,13020151 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10541899 0,13013572 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10541899 0,13006999 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10541899 0,13000433 ! smooth muscle contraction GO:0006939 48 21 0,000 0,10541899 0,12993874 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10541899 0,12987322 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10541899 0,12980776 ! plasma membrane fusion GO:0045026 33 21 0,000 0,10541899 0,12974236 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10541899 0,12967703 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10541899 0,12961177 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10541899 0,12954657 ! sensory perception of pain GO:0019233 33 21 0,000 0,10541899 0,12948144 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10541899 0,12941638 ! collagen fibril organization GO:0030199 62 21 0,000 0,10541899 0,12935137 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,10541899 0,12928644 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,10541899 0,12922157 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10541899 0,12915676 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10541899 0,12909202 ! collagen catabolic process GO:0030574 29 21 0,000 0,10541899 0,12902735 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10541899 0,12896274 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10541899 0,12889819 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10541899 0,12883371 ! actin filament-based movement GO:0030048 47 21 0,000 0,10541899 0,12876929 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,11015342 0,13448516 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11015342 0,13441798 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11015342 0,13435088 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11015342 0,13428383 ! microtubule-based transport GO:0010970 59 22 0,000 0,11015342 0,13421686 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11015342 0,13414995 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11015342 0,13408311 ! fucose metabolic process GO:0006004 44 22 0,000 0,11015342 0,13401634 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11015342 0,13394963 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11015342 0,13388299 ! stem cell differentiation GO:0048863 57 22 0,000 0,11015342 0,13381641 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11015342 0,1337499 ! cytolysis GO:0019835 27 22 0,000 0,11015342 0,13368346 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11015342 0,13361708 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11015342 0,13355077 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,11015342 0,13348453 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,11015342 0,13341835 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11015342 0,13335223 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11015342 0,13328618 ! sarcomere organization GO:0045214 32 22 0,000 0,11015342 0,1332202 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11015342 0,13315428 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11015342 0,13308843 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11015342 0,13302264 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,11015342 0,13295692 ! protein stabilization GO:0050821 41 22 0,000 0,11015342 0,13289126 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,11486293 0,13850451 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11486293 0,13843618 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11486293 0,13836792 ! gluconeogenesis GO:0006094 38 23 0,000 0,11486293 0,13829972 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11486293 0,13823159 ! viral genome replication GO:0019079 44 23 0,000 0,11486293 0,13816353 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11486293 0,13809554 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11486293 0,13802761 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11486293 0,13795975 ! axis specification GO:0009798 43 23 0,000 0,11486293 0,13789196 ! visual behavior GO:0007632 46 23 0,000 0,11486293 0,13782423 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11486293 0,13775657 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11486293 0,13768898 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11486293 0,13762145 ! peroxisome organization GO:0007031 43 23 0,000 0,11486293 0,13755399 ! lysosome organization GO:0007040 47 23 0,000 0,11486293 0,13748659 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,11486293 0,13741926 ! vesicle targeting GO:0006903 49 23 0,000 0,11486293 0,137352 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11486293 0,1372848 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11486293 0,13721767 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11486293 0,1371506 ! DNA modification GO:0006304 36 23 0,000 0,11486293 0,1370836 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11486293 0,13701667 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11486293 0,1369498 ! hormone transport GO:0009914 41 23 0,000 0,11486293 0,13688299 ! cell-cell recognition GO:0009988 28 23 0,000 0,11486293 0,13681625 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11486293 0,13674958 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11486293 0,13668297 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11486293 0,13661642 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,11954764 0,14211917 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,11954764 0,14205005 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11954764 0,14198099 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,11954764 0,141912 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11954764 0,14184308 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11954764 0,14177422 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,11954764 0,14170543 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11954764 0,14163671 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,11954764 0,14156805 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,11954764 0,14149946 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,11954764 0,14143094 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,11954764 0,14136248 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11954764 0,14129409 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,11954764 0,14122577 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11954764 0,14115751 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11954764 0,14108932 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,11954764 0,14102119 ! membrane depolarization GO:0051899 45 24 0,000 0,11954764 0,14095313 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11954764 0,14088514 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11954764 0,14081721 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,11954764 0,14074935 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11954764 0,14068155 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11954764 0,14061381 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11954764 0,14054615 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,11954764 0,14047854 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,11954764 0,14041101 ! regulation of amine transport GO:0051952 41 24 0,000 0,11954764 0,14034353 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,11954764 0,14027613 ! leukocyte adhesion GO:0007159 55 25 0,000 0,1242077 0,14567422 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,1242077 0,14560432 ! phototransduction GO:0007602 37 25 0,000 0,1242077 0,14553448 ! keratinization GO:0031424 37 25 0,000 0,1242077 0,14546472 ! vacuole organization GO:0007033 49 25 0,000 0,1242077 0,14539502 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,1242077 0,14532538 ! chromosome condensation GO:0030261 48 25 0,000 0,1242077 0,14525582 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,1242077 0,14518632 ! immunoglobulin production GO:0002377 62 25 0,000 0,1242077 0,14511688 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,1242077 0,14504751 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,1242077 0,14497821 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,12884321 0,15031708 ! initiation of viral infection GO:0019059 60 26 0,000 0,12884321 0,15024533 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,12884321 0,15017365 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12884321 0,15010204 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12884321 0,15003049 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12884321 0,14995901 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,12884321 0,1498876 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,12884321 0,14981626 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,12884321 0,14974499 ! digestive system process GO:0022600 49 26 0,000 0,12884321 0,14967378 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12884321 0,14960265 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12884321 0,14953158 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12884321 0,14946057 ! neural crest cell development GO:0014032 59 26 0,000 0,12884321 0,14938964 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12884321 0,14931877 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12884321 0,14924797 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12884321 0,14917724 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12884321 0,14910657 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,12884321 0,14903597 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,12884321 0,14896544 ! blastocyst development GO:0001824 50 26 0,000 0,12884321 0,14889497 ! telomere organization GO:0032200 46 26 0,000 0,12884321 0,14882457 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12884321 0,14875424 ! alditol metabolic process GO:0019400 44 26 0,000 0,12884321 0,14868397 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12884321 0,14861377 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13345432 0,1538598 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13345432 0,15378722 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,13345432 0,15371472 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13345432 0,15364228 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,13345432 0,15356991 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,13345432 0,15349761 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13345432 0,15342537 ! iron ion transport GO:0006826 65 27 0,000 0,13345432 0,15335321 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,13345432 0,15328111 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13345432 0,15320908 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,13345432 0,15313711 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,13345432 0,15306522 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,13345432 0,15299339 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,13345432 0,15292163 ! neuron fate commitment GO:0048663 52 28 0,000 0,13804116 0,1581034 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,13804116 0,15802931 ! vesicle docking GO:0048278 55 28 0,000 0,13804116 0,15795529 ! circadian rhythm GO:0007623 56 28 0,000 0,13804116 0,15788134 ! dendrite development GO:0016358 67 28 0,000 0,13804116 0,15780746 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13804116 0,15773365 ! sperm motility GO:0030317 37 28 0,000 0,13804116 0,15765991 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13804116 0,15758624 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13804116 0,15751264 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13804116 0,1574391 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13804116 0,15736563 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13804116 0,15729223 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13804116 0,15721891 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13804116 0,15714564 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13804116 0,15707245 ! lipid oxidation GO:0034440 48 28 0,000 0,13804116 0,15699933 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13804116 0,15692627 ! translational initiation GO:0006413 66 29 0,000 0,14260384 0,16203776 ! catechol metabolic process GO:0009712 55 29 0,000 0,14260384 0,16196243 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,14260384 0,16188717 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,14260384 0,16181198 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,14260384 0,16173686 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,14260384 0,1616618 ! synaptogenesis GO:0007416 46 29 0,000 0,14260384 0,16158682 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,14260384 0,16151191 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14260384 0,16143707 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14260384 0,16136229 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,1471425 0,16642089 ! phenol metabolic process GO:0018958 56 30 0,000 0,1471425 0,16634388 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,1471425 0,16626694 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,1471425 0,16619007 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,1471425 0,16611328 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,1471425 0,16603655 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,1471425 0,16595989 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,1471425 0,16588331 ! acute-phase response GO:0006953 50 30 0,000 0,1471425 0,16580679 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,1471425 0,16573035 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,1471425 0,16565398 ! myofibril assembly GO:0030239 50 30 0,000 0,1471425 0,16557767 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,1471425 0,16550144 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,1471425 0,16542528 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,1471425 0,16534919 ! cell fate determination GO:0001709 64 30 0,000 0,1471425 0,16527316 ! phospholipid transport GO:0015914 65 30 0,000 0,1471425 0,16519721 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,1471425 0,16512133 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,1471425 0,16504551 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,1471425 0,16496977 GO:0043433|negative regulation of transcription factor activity, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15165726 0,16995353 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15165726 0,1698756 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15165726 0,16979775 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15165726 0,16971997 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15165726 0,16964226 ! peptide transport GO:0015833 60 31 0,000 0,15165726 0,16956462 ! detection of light stimulus GO:0009583 44 31 0,000 0,15165726 0,16948705 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,15165726 0,16940955 ! natural killer cell activation GO:0030101 50 31 0,000 0,15165726 0,16933213 ! cofactor catabolic process GO:0051187 54 31 0,000 0,15165726 0,16925477 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15165726 0,16917748 ! eye morphogenesis GO:0048592 65 31 0,000 0,15165726 0,16910027 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15165726 0,16902313 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15614825 0,17394901 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,15614825 0,17386972 ! collagen metabolic process GO:0032963 49 32 0,000 0,15614825 0,17379051 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,15614825 0,17371137 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,15614825 0,1736323 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,15614825 0,17355331 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,15614825 0,17347439 ! muscle cell development GO:0055001 52 32 0,000 0,15614825 0,17339553 ! mesoderm formation GO:0001707 73 32 0,000 0,15614825 0,17331675 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,15614825 0,17323804 ! BMP signaling pathway GO:0030509 71 32 0,000 0,15614825 0,17315941 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,15614825 0,17308084 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15614825 0,17300235 ! gene silencing GO:0016458 71 32 0,000 0,15614825 0,17292392 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,16061559 0,17779061 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,16061559 0,17771009 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,16061559 0,17762964 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,16061559 0,17754927 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,16061559 0,17746897 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,16061559 0,17738874 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,1650594 0,18221424 ! cholesterol transport GO:0030301 62 34 0,000 0,1650594 0,18213194 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,1650594 0,18204972 ! spliceosome assembly GO:0000245 75 34 0,000 0,1650594 0,18196756 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,1650594 0,18188548 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,1650594 0,18180348 ! formation of primary germ layer GO:0001704 76 34 0,000 0,1650594 0,18172155 ! cell fate specification GO:0001708 56 34 0,000 0,1650594 0,18163969 ! adult locomotory behavior GO:0008344 62 34 0,000 0,1650594 0,18155791 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,16947981 0,18633627 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,16947981 0,18625245 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,16947981 0,1861687 ! membrane docking GO:0022406 69 35 0,000 0,16947981 0,18608503 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,16947981 0,18600143 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,16947981 0,18591791 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,16947981 0,18583446 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,16947981 0,18575109 ! ceramide metabolic process GO:0006672 72 35 0,000 0,16947981 0,1856678 ! sterol transport GO:0015918 63 35 0,000 0,16947981 0,18558457 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,16947981 0,18550143 ! vesicle localization GO:0051648 70 35 0,000 0,16947981 0,18541835 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,17387695 0,19014386 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17387695 0,19005878 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17387695 0,18997378 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,17387695 0,18988886 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17387695 0,18980401 ! regulation of proteolysis GO:0030162 77 36 0,000 0,17387695 0,18971924 ! aerobic respiration GO:0009060 56 36 0,000 0,17387695 0,18963455 ! embryonic organ development GO:0048568 67 36 0,000 0,17387695 0,18954992 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17387695 0,18946538 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,17387695 0,18938091 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,17825092 0,19405838 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,17825092 0,19397194 ! odontogenesis GO:0042476 74 37 0,000 0,17825092 0,19388558 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17825092 0,19379929 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,17825092 0,19371308 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,17825092 0,19362695 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,17825092 0,19354089 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,18260186 0,19817697 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,18260186 0,19808897 ! organic anion transport GO:0015711 82 38 0,000 0,18260186 0,19800104 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18260186 0,1979132 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,18260186 0,19782543 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,18260186 0,19773774 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18260186 0,19765013 ! spermatid development GO:0007286 69 38 0,000 0,18260186 0,1975626 ! glycogen metabolic process GO:0005977 63 38 0,000 0,18260186 0,19747514 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,18692989 0,20206625 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,18692989 0,20197688 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,18692989 0,20188758 ! glucan metabolic process GO:0044042 64 39 0,000 0,18692989 0,20179837 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,19123512 0,20635485 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,19123512 0,20626375 ! learning GO:0007612 82 40 0,000 0,19123512 0,20617272 ! mismatch repair GO:0006298 58 40 0,000 0,19123512 0,20608178 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,19123512 0,20599091 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19551767 0,21051109 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19551767 0,21041836 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19551767 0,2103257 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,19551767 0,21023313 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,19551767 0,21014064 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,19551767 0,21004823 ! feeding behavior GO:0007631 69 41 0,000 0,19551767 0,2099559 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,19551767 0,20986365 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,19551767 0,20977148 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,19551767 0,2096794 ! spermatid differentiation GO:0048515 73 41 0,000 0,19551767 0,20958739 ! RNA modification GO:0009451 64 41 0,000 0,19551767 0,20949547 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,19977767 0,21396617 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,19977767 0,21387241 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,19977767 0,21377873 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,19977767 0,21368513 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,19977767 0,21359162 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,20401523 0,21802677 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,20401523 0,21793144 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,20401523 0,21783619 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,20401523 0,21774102 ! ion transmembrane transport GO:0034220 79 43 0,000 0,20401523 0,21764594 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,20823046 0,22204584 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,20823046 0,22194896 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,20823046 0,22185217 ! striated muscle contraction GO:0006941 85 44 0,000 0,20823046 0,22175546 ! phagocytosis GO:0006909 105 44 0,000 0,20823046 0,22165883 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,20823046 0,22156229 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,2124235 0,22592538 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,2124235 0,22582707 ! biopolymer methylation GO:0043414 91 45 0,000 0,2124235 0,22572884 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,2124235 0,2256307 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,2124235 0,22553264 ! maintenance of location in cell GO:0051651 101 45 0,000 0,2124235 0,22543467 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,21659444 0,22976128 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,21659444 0,22966155 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,21659444 0,22956192 ! cell growth GO:0016049 90 46 0,000 0,21659444 0,22946237 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,21659444 0,22936291 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,22487053 0,2380237 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,22487053 0,23792062 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,22487053 0,23781762 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,22487053 0,23771472 ! methylation GO:0032259 97 48 0,000 0,22487053 0,2376119 ! response to calcium ion GO:0051592 94 49 0,000 0,2289759 0,24184528 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,23305965 0,24605217 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,23305965 0,24594589 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,23305965 0,24583969 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,23305965 0,24573359 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,23305965 0,24562758 ! viral infectious cycle GO:0019058 104 51 0,000 0,23712188 0,2498011 ! peptide metabolic process GO:0006518 80 51 0,000 0,23712188 0,24969343 ! Notch signaling pathway GO:0007219 111 52 0,000 0,24116271 0,25383908 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,24116271 0,25372976 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,24116271 0,25362053 ! excretion GO:0007588 87 52 0,000 0,24116271 0,2535114 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,24116271 0,25340236 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,24116271 0,25329342 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,24116271 0,25318457 ! amino acid activation GO:0043038 98 52 0,000 0,24116271 0,25307581 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,24518224 0,25718344 ! inner ear development GO:0048839 89 53 0,000 0,24518224 0,25707306 ! chromatin remodeling GO:0006338 122 53 0,000 0,24518224 0,25696277 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,24518224 0,25685258 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,24518224 0,25674249 ! regulation of translational initiation GO:0006446 87 54 0,000 0,2491806 0,26081757 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,2491806 0,26070587 ! neuromuscular process GO:0050905 107 54 0,000 0,2491806 0,26059427 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,2491806 0,26048276 ! membrane fusion GO:0006944 122 54 0,000 0,2491806 0,26037135 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,2491806 0,26026003 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,2491806 0,26014881 ! RNA catabolic process GO:0006401 103 55 0,000 0,25315789 0,26418827 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,25315789 0,26407546 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,25315789 0,26396275 ! cell recognition GO:0008037 98 55 0,000 0,25315789 0,26385014 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,25315789 0,26373763 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,25711423 0,26774512 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,25711423 0,26763104 ! RNA elongation GO:0006354 90 56 0,000 0,25711423 0,26751706 ! chloride transport GO:0006821 102 57 0,000 0,26104971 0,27149615 ! regulation of actin filament length GO:0030832 118 58 0,000 0,26496446 0,27545029 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,26496446 0,27533313 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26496446 0,27521606 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,26496446 0,2750991 ! gastrulation GO:0007369 122 58 0,000 0,26496446 0,27498223 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,26496446 0,27486547 ! maintenance of location GO:0051235 124 58 0,000 0,26496446 0,2747488 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,27273218 0,28268337 ! regulation of endocytosis GO:0030100 104 60 0,000 0,27273218 0,28256349 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,27273218 0,28244371 ! adult behavior GO:0030534 104 60 0,000 0,27273218 0,28232403 ! regulation of cellular component size GO:0032535 125 61 0,000 0,27658536 0,28619146 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,27658536 0,28607029 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,27658536 0,28594923 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,27658536 0,28582827 ! camera-type eye development GO:0043010 126 61 0,000 0,27658536 0,28570741 ! proton transport GO:0015992 117 61 0,000 0,27658536 0,28558666 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,28041824 0,28942195 ! tRNA processing GO:0008033 102 62 0,000 0,28041824 0,28929973 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,28423091 0,29310938 ! mesoderm development GO:0007498 128 63 0,000 0,28423091 0,2929857 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,28423091 0,29286213 ! hydrogen transport GO:0006818 121 64 0,000 0,28802349 0,29664477 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,28802349 0,29651976 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,28802349 0,29639486 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,29179609 0,30015067 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,29179609 0,30002434 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,29179609 0,29989812 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,29928172 0,30746226 ! extracellular matrix organization GO:0030198 146 68 0,000 0,30299497 0,31114616 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,30299497 0,31101543 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,30299497 0,31088481 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,30299497 0,31075429 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,30668865 0,31441057 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,30668865 0,31427868 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,30668865 0,31414691 ! single fertilization GO:0007338 83 69 0,000 0,30668865 0,31401525 ! cell redox homeostasis GO:0045454 114 70 0,000 0,31036286 0,3176441 ! activation of immune response GO:0002253 120 70 0,000 0,31036286 0,31751108 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,31036286 0,31737818 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,3140177 0,32098127 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,31765327 0,32456167 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,31765327 0,32442598 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,31765327 0,32429041 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,31765327 0,32415495 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,32126968 0,32770849 ! regulation of immune effector process GO:0002697 156 73 0,000 0,32126968 0,32757171 ! acute inflammatory response GO:0002526 118 74 0,000 0,32486702 0,33110143 ! amino acid transport GO:0006865 148 74 0,000 0,32486702 0,33096336 ! transition metal ion transport GO:0000041 143 75 0,000 0,3284454 0,33446941 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,3284454 0,33433004 ! eye development GO:0001654 155 75 0,000 0,3284454 0,3341908 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,33200491 0,33767194 ! learning or memory GO:0007611 161 76 0,000 0,33200491 0,33753141 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,33200491 0,33739101 ! amine catabolic process GO:0009310 136 77 0,000 0,33554565 0,34084741 ! neurotransmitter transport GO:0006836 142 77 0,000 0,33554565 0,34070575 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,33554565 0,3405642 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,33554565 0,34042277 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,33554565 0,34028145 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,33906773 0,34371056 ! antigen processing and presentation GO:0019882 117 78 0,000 0,33906773 0,343568 ! fertilization GO:0009566 99 78 0,000 0,33906773 0,34342556 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,34257123 0,3468303 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,34257123 0,34668663 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,34257123 0,34654307 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,34605626 0,34992361 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,34952291 0,35328278 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,35640148 0,36008636 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,35640148 0,3599375 ! inorganic anion transport GO:0015698 156 83 0,000 0,35640148 0,35978876 ! digestion GO:0007586 130 84 0,000 0,35981358 0,36308326 ! regulation of ligase activity GO:0051340 147 84 0,000 0,35981358 0,36293335 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,36320769 0,36620569 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,36320769 0,36605461 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,3699423 0,37268826 ! cellular respiration GO:0045333 143 88 0,000 0,37328299 0,37589874 ! sensory perception of smell GO:0007608 117 88 0,000 0,37328299 0,37574386 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,37328299 0,3755891 ! cellular defense response GO:0006968 123 89 0,000 0,37660606 0,3787767 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,3799116 0,38194405 ! response to unfolded protein GO:0006986 139 90 0,000 0,3799116 0,38178694 ! defense response to bacterium GO:0042742 112 91 0,000 0,38319971 0,38493293 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,38972399 0,39132581 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,38972399 0,39116504 ! vitamin metabolic process GO:0006766 153 93 0,000 0,38972399 0,3910044 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,39296034 0,39408954 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,39296034 0,39392783 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,39617962 0,39699213 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,39617962 0,39682936 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,39617962 0,39666673 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,40256732 0,40289716 ! mRNA transport GO:0051028 185 100 0,000 0,41202306 0,41219178 ! positive regulation of immune response GO:0050778 175 100 0,000 0,41202306 0,41202306