pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6557-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! hormone-mediated signaling GO:0009755 22 22 5,000 6,514E-09 1,2E-05 ! response to hormone stimulus GO:0009725 102 100 8,000 2,555E-08 2,354E-05 ! release of cytochrome c from mitochondria GO:0001836 9 8 3,000 1,557E-07 9,565E-05 ! cell cycle checkpoint GO:0000075 42 41 5,000 3,544E-07 1,633E-04 ! regulation of mitotic cell cycle GO:0007346 72 69 6,000 4,603E-07 1,697E-04 ! apoptotic mitochondrial changes GO:0008637 11 10 3,000 4,622E-07 1,42E-04 ! cellular response to hormone stimulus GO:0032870 48 46 5,000 7,187E-07 1,892E-04 ! regulation of DNA metabolic process GO:0051052 51 50 5,000 1,193E-06 2,749E-04 ! interphase of mitotic cell cycle GO:0051329 52 51 5,000 1,345E-06 2,755E-04 GO:0051325|interphase, ! aging GO:0007568 32 31 4,000 2,198E-06 4,051E-04 ! prostate gland development GO:0030850 5 5 2,000 3,362E-06 5,633E-04 ! T cell lineage commitment GO:0002360 5 5 2,000 3,362E-06 5,163E-04 ! response to drug GO:0042493 37 37 4,000 5,461E-06 7,742E-04 ! DNA damage response, signal transduction GO:0042770 37 37 4,000 5,461E-06 7,189E-04 ! regulation of lipid kinase activity GO:0043550 6 6 2,000 6,69E-06 8,22E-04 ! ER overload response GO:0006983 6 6 2,000 6,69E-06 7,706E-04 ! negative regulation of T cell proliferation GO:0042130 6 6 2,000 6,69E-06 7,253E-04 GO:0070667|negative regulation of mast cell proliferation, ! DNA damage checkpoint GO:0000077 19 19 3,000 8,138E-06 8,333E-04 ! double-strand break repair via homologous recombination GO:0000724 7 7 2,000 1,165E-05 1,13E-03 GO:0000725|recombinational repair, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 2,000 1,165E-05 1,073E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to gamma radiation GO:0010332 8 7 2,000 1,165E-05 1,022E-03 ! negative regulation of T cell activation GO:0050868 7 7 2,000 1,165E-05 9,759E-04 ! DNA integrity checkpoint GO:0031570 21 21 3,000 1,244E-05 9,964E-04 ! response to estrogen stimulus GO:0043627 23 23 3,000 1,821E-05 1,398E-03 ! negative regulation of bone remodeling GO:0046851 8 8 2,000 1,855E-05 1,367E-03 ! T cell homeostasis GO:0043029 8 8 2,000 1,855E-05 1,315E-03 ! gland development GO:0048732 51 49 4,000 2,241E-05 1,53E-03 ! cell cycle arrest GO:0007050 49 49 4,000 2,241E-05 1,475E-03 ! negative regulation of tissue remodeling GO:0034104 9 9 2,000 2,768E-05 1,759E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 3,000 3,026E-05 1,859E-03 ! double-strand break repair GO:0006302 27 26 3,000 3,026E-05 1,799E-03 ! reciprocal meiotic recombination GO:0007131 10 10 2,000 3,934E-05 2,266E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 2,000 3,934E-05 2,197E-03 ! lymphocyte homeostasis GO:0002260 10 10 2,000 3,934E-05 2,133E-03 ! negative regulation of homeostatic process GO:0032845 10 10 2,000 3,934E-05 2,072E-03 ! negative regulation of cell cycle GO:0045786 92 91 5,000 4,015E-05 2,055E-03 ! response to UV GO:0009411 29 29 3,000 4,732E-05 2,357E-03 ! negative regulation of lymphocyte activation GO:0051250 11 11 2,000 5,382E-05 2,611E-03 ! response to reactive oxygen species GO:0000302 31 30 3,000 5,432E-05 2,567E-03 ! negative regulation of cell growth GO:0030308 32 32 3,000 7,053E-05 3,25E-03 ! collagen metabolic process GO:0032963 12 12 2,000 7,141E-05 3,21E-03 ! G1 phase GO:0051318 13 12 2,000 7,141E-05 3,133E-03 ! negative regulation of cell size GO:0045792 33 33 3,000 7,984E-05 3,422E-03 ! regulation of lipid metabolic process GO:0019216 34 34 3,000 9,002E-05 3,77E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 2,000 9,236E-05 3,783E-03 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 2,000 9,236E-05 3,701E-03 ! vasculogenesis GO:0001570 13 13 2,000 9,236E-05 3,622E-03 ! mitochondrial membrane organization GO:0007006 13 13 2,000 9,236E-05 3,546E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 2,000 9,236E-05 3,474E-03 ! cell aging GO:0007569 13 13 2,000 9,236E-05 3,405E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 9,236E-05 3,338E-03 ! negative regulation of intracellular transport GO:0032387 13 13 2,000 9,236E-05 3,274E-03 ! negative regulation of leukocyte activation GO:0002695 13 13 2,000 9,236E-05 3,212E-03 ! tissue homeostasis GO:0001894 13 13 2,000 9,236E-05 3,152E-03 GO:0048871|multicellular organismal homeostasis, ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 1,011E-04 3,388E-03 ! response to steroid hormone stimulus GO:0048545 35 35 3,000 1,011E-04 3,327E-03 ! regulation of cell size GO:0008361 68 68 4,000 1,107E-04 3,579E-03 ! response to nutrient levels GO:0031667 69 69 4,000 1,187E-04 3,772E-03 ! negative regulation of protein kinase activity GO:0006469 37 37 3,000 1,262E-04 3,942E-03 ! negative regulation of growth GO:0045926 37 37 3,000 1,262E-04 3,876E-03 ! negative regulation of kinase activity GO:0033673 38 38 3,000 1,403E-04 4,239E-03 ! urogenital system development GO:0001655 38 38 3,000 1,403E-04 4,171E-03 ! response to extracellular stimulus GO:0009991 72 72 4,000 1,454E-04 4,254E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 1,455E-04 4,189E-03 ! response to ionizing radiation GO:0010212 16 15 2,000 1,455E-04 4,125E-03 ! leukocyte homeostasis GO:0001776 15 15 2,000 1,455E-04 4,062E-03 ! negative regulation of cell activation GO:0050866 15 15 2,000 1,455E-04 4,002E-03 ! negative regulation of transferase activity GO:0051348 40 40 3,000 1,719E-04 4,659E-03 ! response to oxidative stress GO:0006979 76 75 4,000 1,765E-04 4,715E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 2,000 1,782E-04 4,69E-03 ! response to protein stimulus GO:0051789 42 42 3,000 2,084E-04 5,408E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 2,152E-04 5,51E-03 ! response to toxin GO:0009636 18 17 2,000 2,152E-04 5,434E-03 ! reproductive structure development GO:0048608 43 43 3,000 2,285E-04 5,691E-03 ! mitochondrion organization GO:0007005 44 43 3,000 2,285E-04 5,616E-03 ! homeostasis of number of cells GO:0048872 44 43 3,000 2,285E-04 5,542E-03 ! meiosis I GO:0007127 18 18 2,000 2,57E-04 6,151E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 2,57E-04 6,073E-03 ! B cell differentiation GO:0030183 18 18 2,000 2,57E-04 5,996E-03 ! multicellular organismal metabolic process GO:0044236 19 19 2,000 3,037E-04 6,996E-03 ! regulation of cell cycle process GO:0010564 50 48 3,000 3,51E-04 7,987E-03 ! DNA recombination GO:0006310 48 48 3,000 3,51E-04 7,889E-03 ! leukocyte differentiation GO:0002521 50 49 3,000 3,802E-04 8,443E-03 ! response to nutrient GO:0007584 49 49 3,000 3,802E-04 8,342E-03 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 4,126E-04 8,947E-03 ! negative regulation of protein transport GO:0051224 21 21 2,000 4,126E-04 8,843E-03 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 4,754E-04 0,01007093 ! cell fate commitment GO:0045165 52 52 3,000 4,783E-04 0,01001677 ! response to light stimulus GO:0009416 53 52 3,000 4,783E-04 9,904E-03 ! positive regulation of protein ubiquitination GO:0031398 5 5 1,000 4,902E-04 0,0100383 ! metencephalon development GO:0022037 5 5 1,000 4,902E-04 9,928E-03 ! filopodium assembly GO:0046847 7 5 1,000 4,902E-04 9,82E-03 GO:0030035|microspike assembly, ! mRNA stabilization GO:0048255 5 5 1,000 4,902E-04 9,714E-03 GO:0043489|RNA stabilization, ! amyloid precursor protein catabolic process GO:0042987 5 5 1,000 4,902E-04 9,611E-03 ! fear response GO:0042596 5 5 1,000 4,902E-04 9,51E-03 ! response to UV-B GO:0010224 5 5 1,000 4,902E-04 9,411E-03 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 4,902E-04 9,314E-03 ! response to amine stimulus GO:0014075 5 5 1,000 4,902E-04 9,219E-03 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! decidualization GO:0046697 5 5 1,000 4,902E-04 9,126E-03 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 4,902E-04 9,034E-03 ! postreplication repair GO:0006301 5 5 1,000 4,902E-04 8,945E-03 ! cellular pigmentation GO:0033059 5 5 1,000 4,902E-04 8,857E-03 ! DNA methylation GO:0006306 5 5 1,000 4,902E-04 8,771E-03 GO:0006305|DNA alkylation, ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 1,000 4,902E-04 8,687E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 4,902E-04 8,604E-03 ! oocyte differentiation GO:0009994 5 5 1,000 4,902E-04 8,523E-03 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 4,902E-04 8,443E-03 ! spleen development GO:0048536 5 5 1,000 4,902E-04 8,365E-03 ! blastocyst formation GO:0001825 5 5 1,000 4,902E-04 8,289E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 4,902E-04 8,213E-03 ! response to nicotine GO:0035094 5 5 1,000 4,902E-04 8,139E-03 ! nucleus localization GO:0051647 5 5 1,000 4,902E-04 8,066E-03 ! response to hydrogen peroxide GO:0042542 24 23 2,000 5,44E-04 8,872E-03 ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 5,44E-04 8,794E-03 ! regulation of cell adhesion GO:0030155 56 55 3,000 5,932E-04 9,506E-03 ! mitochondrial transport GO:0006839 24 24 2,000 6,186E-04 9,828E-03 ! T cell differentiation GO:0030217 24 24 2,000 6,186E-04 9,744E-03 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 6,186E-04 9,662E-03 ! reproductive developmental process GO:0003006 56 56 3,000 6,355E-04 9,842E-03 ! extracellular structure organization GO:0043062 56 56 3,000 6,355E-04 9,76E-03 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 4,000 6,74E-04 0,01026602 ! hemopoiesis GO:0030097 104 100 4,000 6,74E-04 0,01018187 ! regulation of protein localization GO:0032880 58 57 3,000 6,799E-04 0,01018703 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 6,994E-04 0,01039564 ! regulation of T cell proliferation GO:0042129 25 25 2,000 6,994E-04 0,01031247 ! negative regulation of immune system process GO:0002683 25 25 2,000 6,994E-04 0,01023063 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 7,32E-04 0,01062209 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of B cell proliferation GO:0030888 6 6 1,000 7,32E-04 0,01053911 ! regulation of activated T cell proliferation GO:0046006 6 6 1,000 7,32E-04 0,01045741 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 7,32E-04 0,01037697 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 7 6 1,000 7,32E-04 0,01029775 ! regulation of vascular permeability GO:0043114 6 6 1,000 7,32E-04 0,01021974 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 7,32E-04 0,0101429 ! negative regulation of ossification GO:0030279 6 6 1,000 7,32E-04 0,01006721 ! regulation of bone resorption GO:0045124 6 6 1,000 7,32E-04 9,993E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 7,32E-04 9,919E-03 ! DNA unwinding during replication GO:0006268 6 6 1,000 7,32E-04 9,847E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 7,32E-04 9,775E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 7,32E-04 9,705E-03 ! nitric oxide metabolic process GO:0046209 6 6 1,000 7,32E-04 9,636E-03 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 1,000 7,32E-04 9,567E-03 ! thymus development GO:0048538 6 6 1,000 7,32E-04 9,5E-03 ! maternal placenta development GO:0001893 6 6 1,000 7,32E-04 9,434E-03 ! regulation of embryonic development GO:0045995 6 6 1,000 7,32E-04 9,368E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 8,806E-04 0,01119326 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 9,814E-04 0,01238846 ! hair follicle morphogenesis GO:0031069 7 7 1,000 1,02E-03 0,01278925 ! amyloid precursor protein metabolic process GO:0042982 7 7 1,000 1,02E-03 0,01270284 ! negative regulation of lipid metabolic process GO:0045833 7 7 1,000 1,02E-03 0,01261758 ! digestive system development GO:0055123 7 7 1,000 1,02E-03 0,01253347 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of mRNA processing GO:0050684 7 7 1,000 1,02E-03 0,01245046 ! membrane protein ectodomain proteolysis GO:0006509 7 7 1,000 1,02E-03 0,01236855 GO:0033619|membrane protein proteolysis, ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 1,02E-03 0,01228771 ! response to X-ray GO:0010165 7 7 1,000 1,02E-03 0,01220792 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,02E-03 0,01212916 ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 1,02E-03 0,01205141 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 1,000 1,02E-03 0,01197465 ! response to estradiol stimulus GO:0032355 7 7 1,000 1,02E-03 0,01189886 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 1,02E-03 0,01182403 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 1,02E-03 0,01175013 ! regulation of mRNA stability GO:0043488 7 7 1,000 1,02E-03 0,01167714 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 1,089E-03 0,01239105 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 1,089E-03 0,01231503 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 2,000 1,089E-03 0,01223994 ! response to radiation GO:0009314 70 68 3,000 1,324E-03 0,0147833 ! B cell activation GO:0042113 31 31 2,000 1,327E-03 0,01472767 ! regulation of DNA replication GO:0006275 32 31 2,000 1,327E-03 0,01463948 ! extracellular matrix organization GO:0030198 31 31 2,000 1,327E-03 0,01455234 ! regulation of intracellular transport GO:0032386 31 31 2,000 1,327E-03 0,01446623 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 1,354E-03 0,01467824 ! T cell selection GO:0045058 8 8 1,000 1,354E-03 0,0145924 ! DNA duplex unwinding GO:0032508 8 8 1,000 1,354E-03 0,01450756 GO:0032392|DNA geometric change, ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,354E-03 0,0144237 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 1,354E-03 0,01434081 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,354E-03 0,01425886 ! alpha-beta T cell activation GO:0046631 8 8 1,000 1,354E-03 0,01417784 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 1,354E-03 0,01409774 ! regulation of fatty acid metabolic process GO:0019217 8 8 1,000 1,354E-03 0,01401854 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,354E-03 0,01394023 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,354E-03 0,01386278 ! regulation of RNA stability GO:0043487 8 8 1,000 1,354E-03 0,01378619 ! actin filament polymerization GO:0030041 9 8 1,000 1,354E-03 0,01371044 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 1,456E-03 0,01466806 ! regulation of cell migration GO:0030334 71 71 3,000 1,555E-03 0,01557114 ! regulation of neuron apoptosis GO:0043523 34 33 2,000 1,594E-03 0,0158809 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,733E-03 0,01717026 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,733E-03 0,01707844 ! RNA polyadenylation GO:0043631 9 9 1,000 1,733E-03 0,0169876 GO:0006378|mRNA polyadenylation, ! response to alkaloid GO:0043279 10 9 1,000 1,733E-03 0,01689772 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,733E-03 0,01680878 ! response to ethanol GO:0045471 9 9 1,000 1,733E-03 0,01672078 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,733E-03 0,01663369 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 1,733E-03 0,01654751 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,733E-03 0,01646221 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 1,733E-03 0,01637779 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 1,733E-03 0,01629423 ! regulation of cellular pH GO:0030641 9 9 1,000 1,733E-03 0,01621152 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 1,733E-03 0,01612964 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,733E-03 0,01604859 ! collagen catabolic process GO:0030574 9 9 1,000 1,733E-03 0,01596834 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,733E-03 0,0158889 ! defense response to virus GO:0051607 9 9 1,000 1,733E-03 0,01581024 ! regulation of bone remodeling GO:0046850 34 34 2,000 1,74E-03 0,01579424 ! multicellular organism reproduction GO:0032504 36 35 2,000 1,893E-03 0,01710464 GO:0048609|reproductive process in a multicellular organism, ! regulation of tissue remodeling GO:0034103 35 35 2,000 1,893E-03 0,0170212 ! positive regulation of cell migration GO:0030335 36 36 2,000 2,055E-03 0,01838642 ! female pregnancy GO:0007565 37 36 2,000 2,055E-03 0,0182976 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 2,156E-03 0,01910557 ! regulation of lipid biosynthetic process GO:0046890 10 10 1,000 2,156E-03 0,01901416 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 2,156E-03 0,01892361 ! centrosome cycle GO:0007098 10 10 1,000 2,156E-03 0,01883393 ! induction of apoptosis via death domain receptors GO:0008625 10 10 1,000 2,156E-03 0,01874509 ! epidermis morphogenesis GO:0048730 10 10 1,000 2,156E-03 0,01865708 ! cell-substrate junction assembly GO:0007044 11 10 1,000 2,156E-03 0,0185699 ! cellular response to unfolded protein GO:0034620 10 10 1,000 2,156E-03 0,01848353 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 2,156E-03 0,01839796 ! neuromuscular junction development GO:0007528 10 10 1,000 2,156E-03 0,01831318 ! regulation of protein binding GO:0043393 11 10 1,000 2,156E-03 0,01822917 ! gland morphogenesis GO:0022612 10 10 1,000 2,156E-03 0,01814593 ! gut development GO:0048565 10 10 1,000 2,156E-03 0,01806345 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,156E-03 0,01798172 ! mRNA 3'-end processing GO:0031124 10 10 1,000 2,156E-03 0,01790072 ! meiosis GO:0007126 37 37 2,000 2,225E-03 0,0183914 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 2,000 2,225E-03 0,01830929 ! regulation of locomotion GO:0040012 79 79 3,000 2,306E-03 0,01888741 ! regulation of cell motion GO:0051270 79 79 3,000 2,306E-03 0,01880383 ! chromosome segregation GO:0007059 38 38 2,000 2,404E-03 0,01951831 ! meiotic cell cycle GO:0051321 38 38 2,000 2,404E-03 0,0194327 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 2,404E-03 0,01934784 ! regulation of homeostatic process GO:0032844 38 38 2,000 2,404E-03 0,01926372 ! tube development GO:0035295 83 81 3,000 2,527E-03 0,0201601 ! respiratory tube development GO:0030323 40 39 2,000 2,591E-03 0,02058617 ! response to unfolded protein GO:0006986 39 39 2,000 2,591E-03 0,02049781 ! respiratory system development GO:0060541 40 39 2,000 2,591E-03 0,02041022 ! lymphocyte differentiation GO:0030098 39 39 2,000 2,591E-03 0,02032336 ! protein oligomerization GO:0051259 39 39 2,000 2,591E-03 0,02023725 ! positive regulation of cell motion GO:0051272 39 39 2,000 2,591E-03 0,02015186 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 2,623E-03 0,0203152 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 2,623E-03 0,0202302 ! endothelial cell migration GO:0043542 11 11 1,000 2,623E-03 0,0201459 ! regulation of viral genome replication GO:0045069 11 11 1,000 2,623E-03 0,02006231 ! cellular response to starvation GO:0009267 11 11 1,000 2,623E-03 0,01997941 ! apoptotic nuclear changes GO:0030262 11 11 1,000 2,623E-03 0,01989719 ! regulation of cellular ketone metabolic process GO:0010565 11 11 1,000 2,623E-03 0,01981564 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 2,623E-03 0,01973476 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,623E-03 0,01965454 ! oogenesis GO:0048477 11 11 1,000 2,623E-03 0,01957497 ! hindbrain development GO:0030902 11 11 1,000 2,623E-03 0,01949604 ! RNA 3'-end processing GO:0031123 11 11 1,000 2,623E-03 0,01941774 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 2,788E-03 0,02055018 ! myeloid cell differentiation GO:0030099 42 40 2,000 2,788E-03 0,0204683 ! positive regulation of cell differentiation GO:0045597 87 85 3,000 3,012E-03 0,0220272 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 3,134E-03 0,02282885 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 3,134E-03 0,02273897 ! xenobiotic metabolic process GO:0006805 12 12 1,000 3,134E-03 0,0226498 ! microtubule organizing center organization GO:0031023 12 12 1,000 3,134E-03 0,02256133 GO:0051297|centrosome organization, ! glycoprotein catabolic process GO:0006516 13 12 1,000 3,134E-03 0,02247354 ! male gonad development GO:0008584 12 12 1,000 3,134E-03 0,02238643 ! renal system process GO:0003014 12 12 1,000 3,134E-03 0,0223 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 3,134E-03 0,02221423 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 3,134E-03 0,02212912 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 3,142E-03 0,02210468 ! protein import into nucleus GO:0006606 44 44 2,000 3,663E-03 0,02566864 ! regeneration GO:0031099 13 13 1,000 3,687E-03 0,02573817 ! post-embryonic development GO:0009791 14 13 1,000 3,687E-03 0,02564104 ! regulation of DNA recombination GO:0000018 13 13 1,000 3,687E-03 0,02554465 ! negative regulation of DNA replication GO:0008156 13 13 1,000 3,687E-03 0,02544897 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 3,687E-03 0,02535402 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 1,000 3,687E-03 0,02525976 ! ureteric bud development GO:0001657 13 13 1,000 3,687E-03 0,02516621 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 3,687E-03 0,02507334 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 3,687E-03 0,02498116 ! regulation of viral reproduction GO:0050792 13 13 1,000 3,687E-03 0,02488966 ! positive regulation of locomotion GO:0040017 13 13 1,000 3,687E-03 0,02479882 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 3,687E-03 0,02470864 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 1,000 3,687E-03 0,02461912 ! blastocyst development GO:0001824 13 13 1,000 3,687E-03 0,02453024 ! protein tetramerization GO:0051262 13 13 1,000 3,687E-03 0,024442 ! brain development GO:0007420 91 90 3,000 3,703E-03 0,02446293 ! DNA replication GO:0006260 91 91 3,000 3,853E-03 0,0253641 ! nuclear import GO:0051170 45 45 2,000 3,905E-03 0,0256125 ! tube morphogenesis GO:0035239 47 46 2,000 4,157E-03 0,02716662 ! regulation of membrane potential GO:0042391 46 46 2,000 4,157E-03 0,02707063 ! protein amino acid acylation GO:0043543 14 14 1,000 4,282E-03 0,02778672 ! hair cycle GO:0042633 14 14 1,000 4,282E-03 0,02768922 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 4,282E-03 0,0275924 ! multicellular organismal response to stress GO:0033555 14 14 1,000 4,282E-03 0,02749626 ! actin polymerization or depolymerization GO:0008154 15 14 1,000 4,282E-03 0,02740079 ! regulation of behavior GO:0050795 14 14 1,000 4,282E-03 0,02730598 ! base-excision repair GO:0006284 14 14 1,000 4,282E-03 0,02721182 ! response to organic cyclic substance GO:0014070 15 14 1,000 4,282E-03 0,02711831 ! DNA modification GO:0006304 14 14 1,000 4,282E-03 0,02702544 ! blood vessel development GO:0001568 95 94 3,000 4,329E-03 0,02722845 ! epidermis development GO:0008544 94 94 3,000 4,329E-03 0,02713584 ! sex differentiation GO:0007548 47 47 2,000 4,418E-03 0,02760232 ! regulation of cell growth GO:0001558 97 96 3,000 4,667E-03 0,02905711 ! vasculature development GO:0001944 97 96 3,000 4,667E-03 0,02895927 ! actin filament organization GO:0007015 50 48 2,000 4,689E-03 0,02900134 ! protein localization in nucleus GO:0034504 48 48 2,000 4,689E-03 0,02890435 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 4,918E-03 0,03021415 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 4,918E-03 0,03011377 ! striated muscle cell differentiation GO:0051146 16 15 1,000 4,918E-03 0,03001406 ! ovarian follicle development GO:0001541 15 15 1,000 4,918E-03 0,029915 ! response to starvation GO:0042594 15 15 1,000 4,918E-03 0,0298166 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 4,918E-03 0,02971884 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 4,918E-03 0,02962172 GO:0090048|negative regulation of transcription regulator activity, ! protein homooligomerization GO:0051260 15 15 1,000 4,918E-03 0,02952523 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 5,022E-03 0,03005173 ! anti-apoptosis GO:0006916 100 99 3,000 5,207E-03 0,03105406 ! ectoderm development GO:0007398 99 99 3,000 5,207E-03 0,03095389 ! negative regulation of transport GO:0051051 51 50 2,000 5,261E-03 0,031179 ! T cell activation GO:0042110 51 50 2,000 5,261E-03 0,03107907 ! regulation of neurogenesis GO:0050767 51 50 2,000 5,261E-03 0,03097977 ! anatomical structure homeostasis GO:0060249 51 50 2,000 5,261E-03 0,03088111 ! protein modification by small protein conjugation GO:0032446 52 51 2,000 5,562E-03 0,03254473 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 5,595E-03 0,03263365 ! positive regulation of cell development GO:0010720 16 16 1,000 5,595E-03 0,0325307 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 5,595E-03 0,0324284 ! lymphocyte proliferation GO:0046651 16 16 1,000 5,595E-03 0,03232675 ! cellular response to nutrient levels GO:0031669 16 16 1,000 5,595E-03 0,03222573 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 5,595E-03 0,03212533 ! positive regulation of catabolic process GO:0009896 16 16 1,000 5,595E-03 0,03202557 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 5,595E-03 0,03192642 ! response to hypoxia GO:0001666 53 53 2,000 6,195E-03 0,03524037 ! regulation of T cell activation GO:0050863 53 53 2,000 6,195E-03 0,03513194 ! regulation of protein transport GO:0051223 53 53 2,000 6,195E-03 0,03502417 GO:0070201|regulation of establishment of protein localization, ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 6,313E-03 0,03557891 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 6,313E-03 0,03547044 ! myelination GO:0042552 17 17 1,000 6,313E-03 0,03536263 ! cell junction assembly GO:0034329 18 17 1,000 6,313E-03 0,03525547 ! tissue remodeling GO:0048771 17 17 1,000 6,313E-03 0,03514895 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 6,313E-03 0,03504308 ! negative regulation of cell development GO:0010721 18 17 1,000 6,313E-03 0,03493785 GO:0050768|negative regulation of neurogenesis, ! pigmentation GO:0043473 17 17 1,000 6,313E-03 0,03483324 ! embryonic organ development GO:0048568 17 17 1,000 6,313E-03 0,03472927 ! response to oxygen levels GO:0070482 55 54 2,000 6,527E-03 0,03580231 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 6,527E-03 0,03569608 ! in utero embryonic development GO:0001701 55 55 2,000 6,87E-03 0,03745717 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 6,87E-03 0,03734667 ! regulation of cell projection organization GO:0031344 19 18 1,000 7,07E-03 0,03832172 ! mononuclear cell proliferation GO:0032943 18 18 1,000 7,07E-03 0,03820934 GO:0070661|leukocyte proliferation, ! negative regulation of DNA binding GO:0043392 19 18 1,000 7,07E-03 0,03809762 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 7,07E-03 0,03798654 ! ensheathment of neurons GO:0007272 18 18 1,000 7,07E-03 0,03787612 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 7,07E-03 0,03776633 ! regulation of nervous system development GO:0051960 57 56 2,000 7,222E-03 0,0384707 ! regulation of binding GO:0051098 60 57 2,000 7,586E-03 0,04029033 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 7,866E-03 0,04165636 ! regulation of pH GO:0006885 19 19 1,000 7,866E-03 0,041537 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 7,866E-03 0,04141832 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 7,866E-03 0,04130032 ! metanephros development GO:0001656 19 19 1,000 7,866E-03 0,04118299 ! cellular response to oxidative stress GO:0034599 19 19 1,000 7,866E-03 0,04106632 ! peripheral nervous system development GO:0007422 19 19 1,000 7,866E-03 0,04095032 ! regulation of protein stability GO:0031647 19 19 1,000 7,866E-03 0,04083496 ! regulation of cell shape GO:0008360 21 19 1,000 7,866E-03 0,04072026 ! placenta development GO:0001890 19 19 1,000 7,866E-03 0,0406062 ! response to heat GO:0009408 19 19 1,000 7,866E-03 0,04049277 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 8,345E-03 0,04284032 ! regulation of cell development GO:0060284 60 59 2,000 8,345E-03 0,04272132 ! protein localization in organelle GO:0033365 59 59 2,000 8,345E-03 0,04260298 ! regulation of muscle development GO:0048634 21 20 1,000 8,7E-03 0,04429374 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 8,7E-03 0,04417172 ! negative regulation of binding GO:0051100 21 20 1,000 8,7E-03 0,04405036 ! nucleus organization GO:0006997 20 20 1,000 8,7E-03 0,04392968 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 8,7E-03 0,04380965 ! female gamete generation GO:0007292 20 20 1,000 8,7E-03 0,04369028 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 8,7E-03 0,04357156 ! regulation of B cell activation GO:0050864 20 20 1,000 8,7E-03 0,04345348 ! protein polymerization GO:0051258 65 60 2,000 8,741E-03 0,0435378 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 9,565E-03 0,04751455 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 2,000 9,565E-03 0,04738683 ! protein import GO:0017038 62 62 2,000 9,565E-03 0,04725978 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 9,565E-03 0,04713342 ! mammary gland development GO:0030879 23 21 1,000 9,572E-03 0,04704561 ! protein amino acid lipidation GO:0006497 21 21 1,000 9,572E-03 0,04692049 ! Notch signaling pathway GO:0007219 22 21 1,000 9,572E-03 0,04679604 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 9,572E-03 0,04667224 ! regulation of action potential in neuron GO:0019228 21 21 1,000 9,572E-03 0,04654909 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 9,572E-03 0,04642659 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 9,572E-03 0,04630474 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 9,993E-03 0,04821396 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 0,01043297 0,05020354 ! cell junction organization GO:0034330 23 22 1,000 0,0104822 0,05030911 ! ovulation cycle process GO:0022602 22 22 1,000 0,0104822 0,05017844 ! erythrocyte differentiation GO:0030218 23 22 1,000 0,0104822 0,05004844 ! male sex differentiation GO:0046661 22 22 1,000 0,0104822 0,04991912 ! biopolymer methylation GO:0043414 22 22 1,000 0,0104822 0,04979046 GO:0032259|methylation, ! epithelial cell differentiation GO:0030855 23 23 1,000 0,0114287 0,05414677 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 0,0114287 0,05400793 ! lipoprotein biosynthetic process GO:0042158 23 23 1,000 0,0114287 0,0538698 ! positive regulation of growth GO:0045927 23 23 1,000 0,0114287 0,05373238 ! female gonad development GO:0008585 23 23 1,000 0,0114287 0,05359566 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,0114287 0,05345963 ! cell projection assembly GO:0030031 25 23 1,000 0,0114287 0,05332429 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 0,01181875 0,05500493 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 0,01181875 0,05486638 ! regulation of action potential GO:0001508 24 24 1,000 0,01241144 0,05747306 ! glucose homeostasis GO:0042593 24 24 1,000 0,01241144 0,05732902 GO:0033500|carbohydrate homeostasis, ! erythrocyte homeostasis GO:0034101 25 24 1,000 0,01241144 0,05718569 ! ovulation cycle GO:0042698 24 24 1,000 0,01241144 0,05704309 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,01241144 0,05690119 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01279885 0,0585317 ! cell part morphogenesis GO:0032990 75 70 2,000 0,0133059 0,06069993 ! growth GO:0040007 70 70 2,000 0,0133059 0,06055006 ! muscle tissue development GO:0060537 72 70 2,000 0,0133059 0,06040092 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01342987 0,06081389 ! cellular component disassembly GO:0022411 26 25 1,000 0,01342987 0,06066484 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,01342987 0,06051651 GO:0046660|female sex differentiation, ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01342987 0,06036891 ! calcium ion homeostasis GO:0055074 71 71 2,000 0,01382434 0,0619909 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 2,000 0,01382434 0,06184043 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01448347 0,06463203 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01448347 0,06447592 ! germ cell development GO:0007281 27 26 1,000 0,01448347 0,06432056 ! pigment metabolic process GO:0042440 26 26 1,000 0,01448347 0,06416594 ! synapse organization GO:0050808 26 26 1,000 0,01448347 0,06401206 ! activation of caspase activity GO:0006919 27 27 1,000 0,01557169 0,06865701 ! cell growth GO:0016049 27 27 1,000 0,01557169 0,06849315 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01557169 0,06833007 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01669402 0,07308096 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 0,01669402 0,07290779 ! developmental growth GO:0048589 28 28 1,000 0,01669402 0,07273543 ! cellular metal ion homeostasis GO:0006875 77 77 2,000 0,01717595 0,07465867 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,01717595 0,07448301 ! metal ion homeostasis GO:0055065 78 78 2,000 0,01777497 0,07689969 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 0,01784994 0,07704318 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,01784994 0,07686317 ! nuclear transport GO:0051169 79 79 2,000 0,01838559 0,07898519 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 2,000 0,01900784 0,08146848 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01903892 0,08141238 GO:0043280|positive regulation of caspase activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01903892 0,08122392 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01903892 0,08103634 ! regulation of ossification GO:0030278 30 30 1,000 0,01903892 0,08084962 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01903892 0,08066376 ! vesicle organization GO:0016050 30 30 1,000 0,01903892 0,08047875 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01903892 0,08029459 ! lymphocyte activation GO:0046649 82 81 2,000 0,01964172 0,0826477 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02026047 0,08505704 ! negative regulation of cytoskeleton organization GO:0051494 32 31 1,000 0,02026047 0,08486373 ! lipoprotein metabolic process GO:0042157 31 31 1,000 0,02026047 0,08467129 ! digestion GO:0007586 31 31 1,000 0,02026047 0,08447973 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,02026047 0,08428903 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,02026047 0,08409919 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,02026047 0,0839102 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,02094445 0,08654849 ! cell redox homeostasis GO:0045454 32 32 1,000 0,02151407 0,08870342 ! muscle fiber development GO:0048747 32 32 1,000 0,02151407 0,08850542 ! cell maturation GO:0048469 32 32 1,000 0,02151407 0,0883083 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02151407 0,08811206 ! kidney development GO:0001822 32 32 1,000 0,02151407 0,08791669 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 0,02151407 0,08772218 ! regulation of cellular localization GO:0060341 86 85 2,000 0,02229386 0,09070106 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,02229386 0,09050128 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,02279923 0,09234939 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,02279923 0,09214687 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,02279923 0,09194524 ! heart development GO:0007507 90 87 2,000 0,02368999 0,09532892 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,02411545 0,09682956 ! response to metal ion GO:0010038 34 34 1,000 0,02411545 0,09661906 ! ear development GO:0043583 34 34 1,000 0,02411545 0,09640948 ! muscle cell differentiation GO:0042692 35 34 1,000 0,02411545 0,0962008 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,02411545 0,09599302 ! secondary metabolic process GO:0019748 34 34 1,000 0,02411545 0,09578614 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,02411545 0,09558015 ! positive regulation of transferase activity GO:0051347 91 88 2,000 0,02440557 0,09652247 GO:0033674|positive regulation of kinase activity, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 2,000 0,02513284 0,09918594 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02546224 0,10027119 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 2,000 0,02662242 0,10461646 ! response to inorganic substance GO:0010035 36 36 1,000 0,02683913 0,10524366 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,02683913 0,10502022 ! regulation of mitosis GO:0007088 37 36 1,000 0,02683913 0,10479772 GO:0051783|regulation of nuclear division, ! gonad development GO:0008406 36 36 1,000 0,02683913 0,10457616 ! tissue morphogenesis GO:0048729 94 93 2,000 0,02815866 0,10948611 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,02824564 0,10959307 GO:0090046|regulation of transcription regulator activity, ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,02824564 0,10936283 ! adaptive immune response GO:0002250 37 37 1,000 0,02824564 0,10913356 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell-matrix adhesion GO:0007160 39 38 1,000 0,02968128 0,11444058 ! axon guidance GO:0007411 39 38 1,000 0,02968128 0,11420167 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,0311456 0,11958611 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,0311456 0,11933749 ! developmental maturation GO:0021700 39 39 1,000 0,0311456 0,11908991 ! blood circulation GO:0008015 99 98 2,000 0,0322029 0,12287772 GO:0003013|circulatory system process, ! DNA catabolic process GO:0006308 41 40 1,000 0,03263812 0,12428112 ! organelle localization GO:0051640 41 40 1,000 0,03263812 0,12402487 ! muscle organ development GO:0007517 102 100 2,000 0,03390172 0,12856146 ! regulation of caspase activity GO:0043281 41 41 1,000 0,0341584 0,12926885 ! rRNA transcription GO:0009303 5 5 0,000 0,03511689 0,13262382 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03511689 0,1323526 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03511689 0,1320825 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03511689 0,13181349 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03511689 0,13154558 ! reproductive cellular process GO:0048610 5 5 0,000 0,03511689 0,13127875 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03511689 0,131013 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03511689 0,13074833 ! water transport GO:0006833 5 5 0,000 0,03511689 0,13048472 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03511689 0,13022218 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03511689 0,12996069 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03511689 0,12970025 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03511689 0,12944085 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03511689 0,12918248 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03511689 0,12892515 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03511689 0,12866883 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03511689 0,12841354 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03511689 0,12815925 ! CTP metabolic process GO:0046036 5 5 0,000 0,03511689 0,12790597 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03511689 0,12765369 ! GTP metabolic process GO:0046039 5 5 0,000 0,03511689 0,12740241 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03511689 0,12715211 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03511689 0,12690279 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03511689 0,12665445 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03511689 0,12640708 ! social behavior GO:0035176 5 5 0,000 0,03511689 0,12616067 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03511689 0,12591522 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03511689 0,12567072 ! memory GO:0007613 5 5 0,000 0,03511689 0,12542718 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03511689 0,12518457 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03511689 0,1249429 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03511689 0,12470216 ! response to lipid GO:0033993 5 5 0,000 0,03511689 0,12446235 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03511689 0,12422346 ! hippocampus development GO:0021766 6 5 0,000 0,03511689 0,12398549 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03511689 0,12374842 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03511689 0,12351226 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03511689 0,123277 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03511689 0,12304263 ! heart looping GO:0001947 5 5 0,000 0,03511689 0,12280915 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03511689 0,12257656 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03511689 0,12234485 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03511689 0,12211401 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03511689 0,12188404 ! pH reduction GO:0045851 5 5 0,000 0,03511689 0,12165493 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03511689 0,12142669 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03511689 0,12119929 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03511689 0,12097275 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03511689 0,12074706 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03511689 0,1205222 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03511689 0,12029818 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03511689 0,120075 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03511689 0,11985264 ! adrenal gland development GO:0030325 5 5 0,000 0,03511689 0,1196311 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03511689 0,11941037 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03511689 0,11919047 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03511689 0,11897137 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03511689 0,11875307 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03511689 0,11853557 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03511689 0,11831887 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03511689 0,11810296 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03511689 0,11788784 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03511689 0,1176735 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03511689 0,11745993 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03511689 0,11724714 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03511689 0,11703512 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03511689 0,11682387 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03511689 0,11661338 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03511689 0,11640364 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03511689 0,11619466 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03511689 0,11598642 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03511689 0,11577893 ! response to ATP GO:0033198 5 5 0,000 0,03511689 0,11557218 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03511689 0,11536617 ! regulation of appetite GO:0032098 5 5 0,000 0,03511689 0,1151609 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03511689 0,11495635 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03511689 0,11475252 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,03511689 0,11454942 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03511689 0,11434704 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03511689 0,11414537 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03511689 0,11394441 ! receptor clustering GO:0043113 5 5 0,000 0,03511689 0,11374415 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03511689 0,1135446 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03511689 0,11334575 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03511689 0,11314759 ! retinol metabolic process GO:0042572 5 5 0,000 0,03511689 0,11295013 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03511689 0,11275335 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03511689 0,11255726 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03511689 0,11236185 ! parturition GO:0007567 5 5 0,000 0,03511689 0,11216711 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03511689 0,11197305 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03511689 0,11177966 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03511689 0,11158694 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03511689 0,11139488 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03511689 0,11120348 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03511689 0,11101273 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03511689 0,11082264 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03511689 0,1106332 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03511689 0,11044441 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03511689 0,11025626 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03511689 0,11006875 ! interaction with symbiont GO:0051702 5 5 0,000 0,03511689 0,10988187 ! cellular extravasation GO:0045123 5 5 0,000 0,03511689 0,10969563 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03511689 0,10951002 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03511689 0,10932504 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03511689 0,10914068 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03511689 0,10895694 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03511689 0,10877382 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03511689 0,10859131 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03511689 0,10840942 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03511689 0,10822813 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03511689 0,10804745 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03511689 0,10786737 ! neuron recognition GO:0008038 5 5 0,000 0,03511689 0,10768789 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03511689 0,10750901 ! hair follicle maturation GO:0048820 5 5 0,000 0,03511689 0,10733072 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03511689 0,10715302 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03511689 0,10697591 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03511689 0,10679938 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03511689 0,10662343 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03511689 0,10644806 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03511689 0,10627327 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,03511689 0,10609905 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03511689 0,10592541 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03511689 0,10575233 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03511689 0,10557981 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03511689 0,10540786 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03511689 0,10523646 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03511689 0,10506562 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03511689 0,10489534 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03511689 0,1047256 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03511689 0,10455642 ! sterol catabolic process GO:0016127 5 5 0,000 0,03511689 0,10438778 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03511689 0,10421968 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03511689 0,10405213 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03511689 0,10388511 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03511689 0,10371863 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03511689 0,10355268 ! zymogen activation GO:0031638 5 5 0,000 0,03511689 0,10338726 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03511689 0,10322237 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03511689 0,103058 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03511689 0,10289415 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,03511689 0,10273083 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03511689 0,10256802 ! nucleosome positioning GO:0016584 5 5 0,000 0,03511689 0,10240573 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03511689 0,10224395 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03511689 0,10208269 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03511689 0,10192193 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03511689 0,10176167 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03511689 0,10160192 ! NADPH regeneration GO:0006740 5 5 0,000 0,03511689 0,10144267 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03511689 0,10128392 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03511689 0,10112566 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03511689 0,1009679 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03511689 0,10081063 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03511689 0,10065385 ! sarcomere organization GO:0045214 5 5 0,000 0,03511689 0,10049755 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03511689 0,10034174 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03511689 0,10018641 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03511689 0,10003157 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03511689 0,0998772 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03511689 0,0997233 ! male genitalia development GO:0030539 5 5 0,000 0,03511689 0,09956988 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03511689 0,09941693 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03511689 0,09926445 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03511689 0,09911244 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03511689 0,09896089 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03511689 0,09880981 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03511689 0,09865918 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03511689 0,09850902 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03511689 0,09835931 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03511689 0,09821005 ! ATP catabolic process GO:0006200 5 5 0,000 0,03511689 0,09806125 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03511689 0,09791289 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03511689 0,09776499 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03511689 0,09761753 ! embryonic gut development GO:0048566 5 5 0,000 0,03511689 0,09747052 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03511689 0,09732394 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03511689 0,09717781 ! activation of innate immune response GO:0002218 5 5 0,000 0,03511689 0,09703212 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03511689 0,09688686 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03511689 0,09674204 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03511689 0,09659765 ! muscle adaptation GO:0043500 5 5 0,000 0,03511689 0,09645369 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03511689 0,09631015 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03511689 0,09616705 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03511689 0,09602437 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03511689 0,09588211 ! defense response to fungus GO:0050832 5 5 0,000 0,03511689 0,09574027 ! lysogeny GO:0030069 5 5 0,000 0,03511689 0,09559885 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03511689 0,09545785 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03511689 0,09531727 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03511689 0,09517709 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03511689 0,09503733 ! mitochondrion localization GO:0051646 5 5 0,000 0,03511689 0,09489798 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03511689 0,09475904 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,03570598 0,09620777 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,03570598 0,09606732 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,03570598 0,09592728 ! protein ubiquitination GO:0016567 43 42 1,000 0,03570598 0,09578765 ! forebrain development GO:0030900 43 42 1,000 0,03570598 0,09564842 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,03570598 0,0955096 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,03570598 0,09537118 ! humoral immune response GO:0006959 44 44 1,000 0,03888123 0,10370204 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,03888123 0,10355218 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,03888123 0,10340275 ! regulation of DNA binding GO:0051101 47 45 1,000 0,04050803 0,10757391 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,04050803 0,10741913 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,04050803 0,10726479 ! protein processing GO:0016485 45 45 1,000 0,04050803 0,10711089 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04199387 0,11088067 ! axon extension GO:0048675 7 6 0,000 0,04199387 0,11072204 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04199387 0,11056387 ! tRNA modification GO:0006400 6 6 0,000 0,04199387 0,11040614 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04199387 0,11024887 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04199387 0,11009204 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04199387 0,10993566 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04199387 0,10977973 ! virus-host interaction GO:0019048 6 6 0,000 0,04199387 0,10962423 ! regulation of S phase GO:0033261 6 6 0,000 0,04199387 0,10946918 ! myotube differentiation GO:0014902 6 6 0,000 0,04199387 0,10931456 ! bone remodeling GO:0046849 6 6 0,000 0,04199387 0,10916038 ! N-glycan processing GO:0006491 6 6 0,000 0,04199387 0,10900663 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04199387 0,10885331 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04199387 0,10870043 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04199387 0,10854798 ! RNA methylation GO:0001510 6 6 0,000 0,04199387 0,10839595 ! cartilage condensation GO:0001502 7 6 0,000 0,04199387 0,10824435 ! succinate metabolic process GO:0006105 7 6 0,000 0,04199387 0,10809317 ! artery development GO:0060840 6 6 0,000 0,04199387 0,10794241 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04199387 0,10779207 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04199387 0,10764215 ! androgen metabolic process GO:0008209 6 6 0,000 0,04199387 0,10749265 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04199387 0,10734356 ! limbic system development GO:0021761 7 6 0,000 0,04199387 0,10719488 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04199387 0,10704662 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,04199387 0,10689877 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04199387 0,10675132 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04199387 0,10660428 ! pathogenesis GO:0009405 6 6 0,000 0,04199387 0,10645764 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04199387 0,10631141 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04199387 0,10616558 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04199387 0,10602015 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04199387 0,10587511 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04199387 0,10573047 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04199387 0,10558623 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04199387 0,10544238 ! arginine metabolic process GO:0006525 6 6 0,000 0,04199387 0,10529892 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04199387 0,10515585 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04199387 0,10501317 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04199387 0,10487088 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04199387 0,10472897 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04199387 0,10458744 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04199387 0,1044463 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04199387 0,10430553 ! V(D)J recombination GO:0033151 6 6 0,000 0,04199387 0,10416515 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04199387 0,10402514 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04199387 0,10388551 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04199387 0,10374626 ! regulation of heart rate GO:0002027 6 6 0,000 0,04199387 0,10360737 ! lipid digestion GO:0044241 6 6 0,000 0,04199387 0,10346886 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04199387 0,10333072 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04199387 0,10319294 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04199387 0,10305553 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04199387 0,10291849 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04199387 0,10278182 ! ruffle organization GO:0031529 6 6 0,000 0,04199387 0,1026455 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04199387 0,10250955 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04199387 0,10237395 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04199387 0,10223871 ! L-amino acid transport GO:0015807 6 6 0,000 0,04199387 0,10210383 ! bone mineralization GO:0030282 6 6 0,000 0,04199387 0,10196931 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04199387 0,10183514 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04199387 0,10170132 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04199387 0,10156786 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04199387 0,10143474 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04199387 0,10130197 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04199387 0,10116955 ! regulation of organ growth GO:0046620 6 6 0,000 0,04199387 0,10103748 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04199387 0,10090575 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04199387 0,10077436 ! response to dsRNA GO:0043331 6 6 0,000 0,04199387 0,10064331 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04199387 0,10051261 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04199387 0,10038224 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04199387 0,10025221 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04199387 0,10012252 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04199387 0,09999316 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04199387 0,09986414 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04199387 0,09973545 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04199387 0,09960709 ! erythrocyte development GO:0048821 6 6 0,000 0,04199387 0,09947906 ! renal water homeostasis GO:0003091 6 6 0,000 0,04199387 0,09935136 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04199387 0,09922398 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04199387 0,09909694 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04199387 0,09897021 ! ribosome assembly GO:0042255 6 6 0,000 0,04199387 0,09884381 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04199387 0,09871774 ! diencephalon development GO:0021536 6 6 0,000 0,04199387 0,09859198 ! fucose catabolic process GO:0019317 6 6 0,000 0,04199387 0,09846655 GO:0042355|L-fucose catabolic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,04199387 0,09834143 ! regulation of cell division GO:0051302 6 6 0,000 0,04199387 0,09821663 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04199387 0,09809215 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04199387 0,09796798 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04199387 0,09784413 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04199387 0,09772059 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04199387 0,09759736 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04199387 0,09747444 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04199387 0,09735183 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04199387 0,09722953 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04199387 0,09710754 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04199387 0,09698585 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04199387 0,09686446 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04199387 0,09674338 ! lymph node development GO:0048535 6 6 0,000 0,04199387 0,09662261 ! organic cation transport GO:0015695 6 6 0,000 0,04199387 0,09650213 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04199387 0,09638195 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04199387 0,09626207 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04199387 0,09614249 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04199387 0,09602321 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04199387 0,09590422 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04199387 0,09578553 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04199387 0,09566713 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04199387 0,09554902 ! alditol metabolic process GO:0019400 6 6 0,000 0,04199387 0,0954312 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04199387 0,09531368 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04199387 0,09519644 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04199387 0,09507949 ! localization within membrane GO:0051668 6 6 0,000 0,04199387 0,09496283 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,04216036 0,09522247 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,04216036 0,09510592 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,04216036 0,09498965 ! regulation of blood pressure GO:0008217 48 47 1,000 0,04383779 0,0986484 ! rhythmic process GO:0048511 47 47 1,000 0,04383779 0,0985281 ! regulation of catabolic process GO:0009894 48 47 1,000 0,04383779 0,09840809 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,04553989 0,10210465 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,04726626 0,10584655 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 0,04726626 0,1057181 ! regulation of ligase activity GO:0051340 50 49 1,000 0,04726626 0,10558995 ! respiratory burst GO:0045730 7 7 0,000 0,04882284 0,10893522 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04882284 0,10880349 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04882284 0,10867209 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04882284 0,108541 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04882284 0,10841023 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04882284 0,10827977 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04882284 0,10814962 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04882284 0,10801979 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04882284 0,10789027 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04882284 0,10776106 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04882284 0,10763216 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,04882284 0,10750357 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04882284 0,10737528 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04882284 0,1072473 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04882284 0,10711963 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04882284 0,10699226 ! axis specification GO:0009798 7 7 0,000 0,04882284 0,10686519 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04882284 0,10673842 ! visual behavior GO:0007632 7 7 0,000 0,04882284 0,10661195 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04882284 0,10648578 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04882284 0,10635991 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04882284 0,10623434 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04882284 0,10610907 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04882284 0,10598408 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04882284 0,1058594 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04882284 0,105735 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04882284 0,1056109 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04882284 0,10548709 ! protein targeting to ER GO:0045047 8 7 0,000 0,04882284 0,10536357 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04882284 0,10524034 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04882284 0,10511739 ! endoderm development GO:0007492 7 7 0,000 0,04882284 0,10499473 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04882284 0,10487236 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04882284 0,10475028 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04882284 0,10462847 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04882284 0,10450695 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04882284 0,10438572 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04882284 0,10426476 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04882284 0,10414408 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04882284 0,10402369 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04882284 0,10390357 ! UV protection GO:0009650 7 7 0,000 0,04882284 0,10378372 ! DNA integration GO:0015074 7 7 0,000 0,04882284 0,10366416 ! myofibril assembly GO:0030239 7 7 0,000 0,04882284 0,10354487 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04882284 0,10342585 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04882284 0,1033071 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04882284 0,10318863 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04882284 0,10307043 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04882284 0,1029525 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04882284 0,10283484 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04882284 0,10271745 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04882284 0,10260033 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04882284 0,10248347 ! axon cargo transport GO:0008088 7 7 0,000 0,04882284 0,10236688 ! eating behavior GO:0042755 7 7 0,000 0,04882284 0,10225055 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04882284 0,10213449 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04882284 0,10201869 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04882284 0,10190316 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04882284 0,10178788 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04882284 0,10167287 ! cranial nerve development GO:0021545 7 7 0,000 0,04882284 0,10155811 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04882284 0,10144362 ! induction of an organ GO:0001759 7 7 0,000 0,04882284 0,10132938 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04882284 0,1012154 GO:0002263|cell activation during immune response, ! autonomic nervous system development GO:0048483 7 7 0,000 0,04882284 0,10110167 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04882284 0,1009882 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04882284 0,10087499 ! platelet activation GO:0030168 8 7 0,000 0,04882284 0,10076202 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04882284 0,10064932 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04882284 0,10053686 ! natural killer cell activation GO:0030101 7 7 0,000 0,04882284 0,10042465 ! NADP metabolic process GO:0006739 7 7 0,000 0,04882284 0,1003127 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04882284 0,10020099 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04882284 0,10008953 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04882284 0,09997832 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04882284 0,09986736 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04882284 0,09975664 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04882284 0,09964617 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04882284 0,09953594 ! cell-cell recognition GO:0009988 8 7 0,000 0,04882284 0,09942595 ! hormone catabolic process GO:0042447 7 7 0,000 0,04882284 0,09931621 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04882284 0,09920671 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04882284 0,09909745 ! oxygen transport GO:0015671 7 7 0,000 0,04882284 0,09898844 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04882284 0,09887966 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04882284 0,09877112 ! regulation of axon extension GO:0030516 7 7 0,000 0,04882284 0,09866282 ! cell killing GO:0001906 7 7 0,000 0,04882284 0,09855475 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04882284 0,09844692 ! adult feeding behavior GO:0008343 7 7 0,000 0,04882284 0,09833933 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04882284 0,09823197 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04882284 0,09812485 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04882284 0,09801796 ! response to cold GO:0009409 7 7 0,000 0,04882284 0,0979113 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,04901646 0,09819276 ! protein maturation GO:0051604 51 51 1,000 0,0507901 0,10163534 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,05258675 0,10511646 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05560411 0,11102749 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05560411 0,11090733 ! positive regulation of translation GO:0045727 8 8 0,000 0,05560411 0,11078743 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05560411 0,11066779 ! superoxide anion generation GO:0042554 8 8 0,000 0,05560411 0,11054841 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05560411 0,11042928 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05560411 0,11031041 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05560411 0,1101918 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05560411 0,11007344 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05560411 0,10995533 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05560411 0,10983748 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05560411 0,10971988 ! zinc ion transport GO:0006829 8 8 0,000 0,05560411 0,10960254 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05560411 0,10948544 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05560411 0,10936859 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05560411 0,109252 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05560411 0,10913565 ! lipid localization GO:0010876 8 8 0,000 0,05560411 0,10901954 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05560411 0,10890369 ! response to cAMP GO:0051591 8 8 0,000 0,05560411 0,10878808 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05560411 0,10867272 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05560411 0,1085576 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05560411 0,10844272 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05560411 0,10832809 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05560411 0,1082137 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05560411 0,10809955 ! sensory perception of taste GO:0050909 8 8 0,000 0,05560411 0,10798564 ! organelle fusion GO:0048284 8 8 0,000 0,05560411 0,10787197 ! pancreas development GO:0031016 8 8 0,000 0,05560411 0,10775854 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05560411 0,10764535 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05560411 0,10753239 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05560411 0,10741968 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05560411 0,1073072 ! sperm motility GO:0030317 8 8 0,000 0,05560411 0,10719495 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05560411 0,10708294 ! glycine metabolic process GO:0006544 8 8 0,000 0,05560411 0,10697116 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05560411 0,10685962 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05560411 0,1067483 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05560411 0,10663722 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05560411 0,10652637 ! Golgi organization GO:0007030 8 8 0,000 0,05560411 0,10641575 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05560411 0,10630536 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05560411 0,1061952 ! fructose metabolic process GO:0006000 8 8 0,000 0,05560411 0,10608527 ! mannose metabolic process GO:0006013 9 8 0,000 0,05560411 0,10597557 ! NAD metabolic process GO:0019674 8 8 0,000 0,05560411 0,10586609 ! sex determination GO:0007530 8 8 0,000 0,05560411 0,10575683 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05560411 0,10564781 ! response to fungus GO:0009620 8 8 0,000 0,05560411 0,105539 ! stem cell differentiation GO:0048863 8 8 0,000 0,05560411 0,10543042 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05560411 0,10532207 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05560411 0,10521393 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05560411 0,10510602 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05560411 0,10499833 ! vasoconstriction GO:0042310 8 8 0,000 0,05560411 0,10489086 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05560411 0,10478361 ! muscle cell development GO:0055001 8 8 0,000 0,05560411 0,10467658 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05560411 0,10456977 ! sensory perception of pain GO:0019233 8 8 0,000 0,05560411 0,10446317 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05560411 0,10435679 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05560411 0,10425063 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05560411 0,10414469 ! chromatin silencing GO:0006342 8 8 0,000 0,05560411 0,10403896 ! tissue regeneration GO:0042246 8 8 0,000 0,05560411 0,10393344 ! salivary gland development GO:0007431 8 8 0,000 0,05560411 0,10382814 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,05560411 0,10372305 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05560411 0,10361817 ! water homeostasis GO:0030104 8 8 0,000 0,05560411 0,10351351 ! cofactor transport GO:0051181 8 8 0,000 0,05560411 0,10340905 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05560411 0,10330481 ! acid secretion GO:0046717 8 8 0,000 0,05560411 0,10320078 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05560411 0,10309695 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05560411 0,10299334 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05560411 0,10288993 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05560411 0,10278673 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05560411 0,10268374 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05560411 0,10258095 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,05560411 0,10247837 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05560411 0,102376 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05560411 0,10227382 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05560411 0,10217186 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05560411 0,10207009 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05560411 0,10196853 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05560411 0,10186717 ! developmental induction GO:0031128 8 8 0,000 0,05560411 0,10176601 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05560411 0,10166505 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05560411 0,10156429 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05560411 0,10146373 ! peptide hormone processing GO:0016486 8 8 0,000 0,05560411 0,10136337 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05560411 0,10126321 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05560411 0,10116325 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,05624752 0,10223292 ! response to virus GO:0009615 54 54 1,000 0,05624752 0,10213219 ! hormone metabolic process GO:0042445 55 54 1,000 0,05624752 0,10203167 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,05811084 0,10530804 ! lactation GO:0007595 10 9 0,000 0,06233801 0,11285752 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06233801 0,11274677 ! positive regulation of cell size GO:0045793 9 9 0,000 0,06233801 0,11263623 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06233801 0,11252592 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06233801 0,11241581 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06233801 0,11230592 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,06233801 0,11219625 ! viral genome replication GO:0019079 9 9 0,000 0,06233801 0,11208679 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06233801 0,11197754 ! copper ion transport GO:0006825 9 9 0,000 0,06233801 0,11186851 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06233801 0,11175969 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06233801 0,11165108 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06233801 0,11154268 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06233801 0,11143449 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06233801 0,11132651 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06233801 0,11121874 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06233801 0,11111118 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06233801 0,11100383 ! phospholipid efflux GO:0033700 9 9 0,000 0,06233801 0,11089668 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06233801 0,11078974 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06233801 0,11068301 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06233801 0,11057648 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06233801 0,11047015 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06233801 0,11036403 ! methionine metabolic process GO:0006555 9 9 0,000 0,06233801 0,11025812 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06233801 0,11015241 ! cerebral cortex development GO:0021987 9 9 0,000 0,06233801 0,1100469 ! response to osmotic stress GO:0006970 9 9 0,000 0,06233801 0,10994159 ! pigmentation during development GO:0048066 9 9 0,000 0,06233801 0,10983648 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06233801 0,10973158 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06233801 0,10962687 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06233801 0,10952236 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06233801 0,10941806 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06233801 0,10931395 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06233801 0,10921004 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06233801 0,10910632 ! L-glutamate transport GO:0015813 9 9 0,000 0,06233801 0,10900281 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,06233801 0,10889949 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06233801 0,10879636 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06233801 0,10869343 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06233801 0,1085907 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06233801 0,10848816 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06233801 0,10838581 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,06233801 0,10828366 ! DNA replication initiation GO:0006270 9 9 0,000 0,06233801 0,10818169 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06233801 0,10807992 GO:0006692|prostanoid metabolic process, ! histone acetylation GO:0016573 9 9 0,000 0,06233801 0,10797835 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06233801 0,10787696 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06233801 0,10777576 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06233801 0,10767475 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06233801 0,10757393 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06233801 0,1074733 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06233801 0,10737286 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06233801 0,1072726 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06233801 0,10717254 ! purine base metabolic process GO:0006144 9 9 0,000 0,06233801 0,10707266 ! gas transport GO:0015669 9 9 0,000 0,06233801 0,10697296 ! cholesterol efflux GO:0033344 9 9 0,000 0,06233801 0,10687345 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06233801 0,10677413 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06233801 0,10667499 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06233801 0,10657603 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06233801 0,10647726 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06233801 0,10637867 ! actin filament-based movement GO:0030048 9 9 0,000 0,06233801 0,10628026 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06233801 0,10618203 ! dephosphorylation GO:0016311 60 59 1,000 0,06577465 0,11193231 ! immune effector process GO:0002252 59 59 1,000 0,06577465 0,11182905 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06902488 0,11724687 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,06902488 0,1171389 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06902488 0,11703114 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,06902488 0,11692357 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06902488 0,11681621 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06902488 0,11670904 ! neuron maturation GO:0042551 10 10 0,000 0,06902488 0,11660206 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06902488 0,11649528 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06902488 0,1163887 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06902488 0,11628231 ! hormone secretion GO:0046879 10 10 0,000 0,06902488 0,11617612 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06902488 0,11607012 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06902488 0,11596431 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,06902488 0,1158587 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06902488 0,11575327 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06902488 0,11564804 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06902488 0,11554301 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06902488 0,11543816 ! glial cell development GO:0021782 10 10 0,000 0,06902488 0,1153335 ! phototransduction GO:0007602 11 10 0,000 0,06902488 0,11522903 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06902488 0,11512475 ! fat cell differentiation GO:0045444 10 10 0,000 0,06902488 0,11502066 ! myoblast differentiation GO:0045445 10 10 0,000 0,06902488 0,11491676 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06902488 0,11481304 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06902488 0,11470951 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06902488 0,11460617 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06902488 0,11450301 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06902488 0,11440004 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06902488 0,11429726 ! plasma membrane organization GO:0007009 10 10 0,000 0,06902488 0,11419466 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06902488 0,11409224 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,06902488 0,11399001 ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06902488 0,11388796 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06902488 0,11378609 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06902488 0,1136844 ! exocrine system development GO:0035272 10 10 0,000 0,06902488 0,1135829 ! embryo implantation GO:0007566 11 10 0,000 0,06902488 0,11348158 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06902488 0,11338044 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06902488 0,11327947 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06902488 0,11317869 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,06902488 0,11307809 ! protein export from nucleus GO:0006611 10 10 0,000 0,06902488 0,11297766 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06902488 0,11287742 ! cytolysis GO:0019835 10 10 0,000 0,06902488 0,11277735 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06902488 0,11267746 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06902488 0,11257774 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06902488 0,1124782 ! histone deacetylation GO:0016575 10 10 0,000 0,06902488 0,11237884 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06902488 0,11227965 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06902488 0,11218064 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06902488 0,1120818 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06902488 0,11198314 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06902488 0,11188465 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06902488 0,11178633 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06902488 0,11168819 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06902488 0,11159022 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06902488 0,11149242 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06902488 0,11139479 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06902488 0,11129733 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06902488 0,11120004 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06902488 0,11110292 ! nerve development GO:0021675 10 10 0,000 0,06902488 0,11100598 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,06902488 0,1109092 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06902488 0,11081259 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06902488 0,11071614 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,06902488 0,11061987 ! protein stabilization GO:0050821 10 10 0,000 0,06902488 0,11052376 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,06972759 0,11155203 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,06972759 0,11145528 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,07173301 0,11456147 ! protein secretion GO:0009306 11 11 0,000 0,07566502 0,12073648 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07566502 0,12063203 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,07566502 0,12052777 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07566502 0,12042369 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07566502 0,12031979 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07566502 0,12021606 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07566502 0,12011252 ! skin development GO:0043588 11 11 0,000 0,07566502 0,12000915 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,07566502 0,11990596 ! signal complex assembly GO:0007172 11 11 0,000 0,07566502 0,11980295 ! microtubule-based transport GO:0010970 11 11 0,000 0,07566502 0,11970011 ! peroxisomal transport GO:0043574 11 11 0,000 0,07566502 0,11959745 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07566502 0,11949497 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,07566502 0,11939266 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,07566502 0,11929053 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,07566502 0,11918857 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07566502 0,11908679 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07566502 0,11898518 ! T cell proliferation GO:0042098 11 11 0,000 0,07566502 0,11888374 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,07566502 0,11878248 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07566502 0,11868139 ! spinal cord development GO:0021510 11 11 0,000 0,07566502 0,11858047 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07566502 0,11847972 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07566502 0,11837914 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,07566502 0,11827874 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07566502 0,1181785 ! digestive system process GO:0022600 11 11 0,000 0,07566502 0,11807844 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07566502 0,11797854 ! fucose metabolic process GO:0006004 11 11 0,000 0,07566502 0,11787881 ! membrane budding GO:0006900 11 11 0,000 0,07566502 0,11777925 ! monoamine transport GO:0015844 11 11 0,000 0,07566502 0,11767986 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07566502 0,11758063 ! body fluid secretion GO:0007589 11 11 0,000 0,07566502 0,11748158 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07566502 0,11738269 ! intermediate filament-based process GO:0045103 11 11 0,000 0,07566502 0,11728396 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07566502 0,1171854 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,07566502 0,11708701 ! membrane depolarization GO:0051899 11 11 0,000 0,07566502 0,11698879 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07566502 0,11689072 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07566502 0,11679282 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,07566502 0,11669509 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,07566502 0,11659752 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07566502 0,11650011 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,07566502 0,11640286 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,07566502 0,11630578 ! muscle maintenance GO:0046716 12 11 0,000 0,07566502 0,11620886 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07566502 0,1161121 ! steroid catabolic process GO:0006706 11 11 0,000 0,07566502 0,1160155 ! endocrine process GO:0050886 11 11 0,000 0,07566502 0,11591906 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07566502 0,11582278 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07566502 0,11572667 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07566502 0,11563071 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,07579998 0,11574098 ! angiogenesis GO:0001525 65 64 1,000 0,07579998 0,11564517 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,07579998 0,11554952 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,07786082 0,11859296 ! regulation of hormone levels GO:0010817 66 65 1,000 0,07786082 0,11849503 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,07993942 0,12155804 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,08203544 0,12464247 ! translational initiation GO:0006413 12 12 0,000 0,08225876 0,12487883 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,08225876 0,12477605 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,08225876 0,12467344 ! initiation of viral infection GO:0019059 12 12 0,000 0,08225876 0,12457099 ! iron ion transport GO:0006826 13 12 0,000 0,08225876 0,12446872 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08225876 0,12436661 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08225876 0,12426467 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,08225876 0,1241629 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,08225876 0,12406129 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,08225876 0,12395985 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08225876 0,12385858 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08225876 0,12375747 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08225876 0,12365652 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08225876 0,12355574 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08225876 0,12345513 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,08225876 0,12335468 ! actomyosin structure organization GO:0031032 12 12 0,000 0,08225876 0,12325439 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,08225876 0,12315426 ! retinoid metabolic process GO:0001523 12 12 0,000 0,08225876 0,1230543 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08225876 0,1229545 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08225876 0,12285486 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08225876 0,12275538 GO:0006505|GPI anchor metabolic process, ! acute-phase response GO:0006953 12 12 0,000 0,08225876 0,12265607 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08225876 0,12255691 ! vacuolar transport GO:0007034 12 12 0,000 0,08225876 0,12245791 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08225876 0,12235908 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08225876 0,1222604 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08225876 0,12216188 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08225876 0,12206353 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,08225876 0,12196532 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08225876 0,12186728 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08225876 0,1217694 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08225876 0,12167167 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08225876 0,1215741 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,08225876 0,12147668 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08225876 0,12137942 ! pallium development GO:0021543 13 12 0,000 0,08225876 0,12128232 ! cell fate determination GO:0001709 12 12 0,000 0,08225876 0,12118537 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,08225876 0,12108858 ! somitogenesis GO:0001756 13 12 0,000 0,08225876 0,12099194 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,08225876 0,12089545 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08225876 0,12079912 ! detection of light stimulus GO:0009583 13 12 0,000 0,08225876 0,12070294 ! synaptogenesis GO:0007416 12 12 0,000 0,08225876 0,12060692 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08225876 0,12051105 ! hormone transport GO:0009914 12 12 0,000 0,08225876 0,12041533 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,08225876 0,12031976 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08225876 0,12022434 ! spermatid differentiation GO:0048515 13 12 0,000 0,08225876 0,12012908 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,08225876 0,12003397 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08225876 0,119939 ! neural tube closure GO:0001843 13 12 0,000 0,08225876 0,11984419 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,08225876 0,11974952 ! negative regulation of translation GO:0017148 12 12 0,000 0,08225876 0,11965501 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,08225876 0,11956065 ! regulation of translation GO:0006417 69 69 1,000 0,08627838 0,12530422 ! sensory perception of sound GO:0007605 71 69 1,000 0,08627838 0,12520555 GO:0050954|sensory perception of mechanical stimulus, ! wound healing GO:0042060 74 70 1,000 0,08842463 0,12821919 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,08880642 0,12867157 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08880642 0,12857049 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08880642 0,12846957 ! phenol metabolic process GO:0018958 13 13 0,000 0,08880642 0,12836881 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,08880642 0,12826821 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08880642 0,12816776 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08880642 0,12806748 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08880642 0,12796734 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08880642 0,12786737 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,08880642 0,12776755 ! keratinization GO:0031424 13 13 0,000 0,08880642 0,12766789 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,08880642 0,12756838 ! patterning of blood vessels GO:0001569 13 13 0,000 0,08880642 0,12746903 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08880642 0,12736983 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,08880642 0,12727079 ! autophagy GO:0006914 13 13 0,000 0,08880642 0,1271719 ! receptor metabolic process GO:0043112 14 13 0,000 0,08880642 0,12707316 ! actin filament bundle formation GO:0051017 13 13 0,000 0,08880642 0,12697458 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,08880642 0,12687615 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,08880642 0,12677787 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,08880642 0,12667975 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08880642 0,12658177 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08880642 0,12648395 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,08880642 0,12638628 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,08880642 0,12628876 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08880642 0,12619139 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08880642 0,12609417 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,08880642 0,1259971 ! vasodilation GO:0042311 14 13 0,000 0,08880642 0,12590018 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08880642 0,12580341 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,08880642 0,12570678 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08880642 0,12561031 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,08880642 0,12551398 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08880642 0,1254178 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08880642 0,12532177 ! immunoglobulin production GO:0002377 13 13 0,000 0,08880642 0,12522589 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08880642 0,12513015 ! cell-cell junction organization GO:0045216 13 13 0,000 0,08880642 0,12503456 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08880642 0,12493911 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,08880642 0,12484381 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08880642 0,12474865 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08880642 0,12465364 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08880642 0,12455878 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08880642 0,12446406 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08880642 0,12436948 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,08880642 0,12427504 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08880642 0,12418075 ! telomere organization GO:0032200 13 13 0,000 0,08880642 0,12408661 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08880642 0,1239926 ! regulation of amine transport GO:0051952 13 13 0,000 0,08880642 0,12389874 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08880642 0,12380502 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,09276503 0,12922597 ! sensory organ development GO:0007423 72 72 1,000 0,09276503 0,12912837 ! neuron fate commitment GO:0048663 14 14 0,000 0,09530831 0,13256847 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,09530831 0,13246849 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,09530831 0,13236867 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,09530831 0,13226899 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,09530831 0,13216946 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,09530831 0,13207009 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,09530831 0,13197086 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,09530831 0,13187179 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,09530831 0,13177286 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,09530831 0,13167408 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,09530831 0,13157544 ! vesicle docking GO:0048278 14 14 0,000 0,09530831 0,13147696 ! superoxide metabolic process GO:0006801 15 14 0,000 0,09530831 0,13137862 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,09530831 0,13128043 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,09530831 0,13118239 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,09530831 0,13108449 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,09530831 0,13098674 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,09530831 0,13088913 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,09530831 0,13079167 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,09530831 0,13069436 GO:0033189|response to vitamin A, ! lysosome organization GO:0007040 14 14 0,000 0,09530831 0,13059719 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,09530831 0,13050016 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,09530831 0,13040328 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,09530831 0,13030654 ! primary neural tube formation GO:0014020 15 14 0,000 0,09530831 0,13020995 ! peptide cross-linking GO:0018149 14 14 0,000 0,09530831 0,1301135 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,09530831 0,13001719 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,09530831 0,12992102 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,09530831 0,129825 ! formation of primary germ layer GO:0001704 14 14 0,000 0,09530831 0,12972911 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,09530831 0,12963337 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,09530831 0,12953777 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,09530831 0,12944231 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,09530831 0,12934699 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,09530831 0,12925182 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,09530831 0,12915678 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,09530831 0,12906188 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,09530831 0,12896712 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,09530831 0,1288725 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,09530831 0,12877802 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,10162846 0,13721704 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,10176475 0,13730046 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,10176475 0,13720002 ! positive regulation of ossification GO:0045778 15 15 0,000 0,10176475 0,13709973 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,10176475 0,13699958 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,10176475 0,13689958 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,10176475 0,13679973 ! response to vitamin GO:0033273 15 15 0,000 0,10176475 0,13670002 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,10176475 0,13660046 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,10176475 0,13650104 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,10176475 0,13640177 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,10176475 0,13630264 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,10176475 0,13620365 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,10176475 0,13610481 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,10176475 0,13600611 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,10176475 0,13590756 ! heme metabolic process GO:0042168 15 15 0,000 0,10176475 0,13580915 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,10176475 0,13571088 ! chromosome condensation GO:0030261 15 15 0,000 0,10176475 0,13561275 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,10176475 0,13551476 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,10176475 0,13541692 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,10176475 0,13531921 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,10176475 0,13522165 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,10176475 0,13512423 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,10176475 0,13502695 ! phospholipid transport GO:0015914 15 15 0,000 0,10176475 0,13492981 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,10176475 0,1348328 ! glutathione metabolic process GO:0006749 16 15 0,000 0,10176475 0,13473594 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,10176475 0,13463922 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,10176475 0,13454263 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,10176475 0,13444619 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,10176475 0,13434988 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,10176475 0,13425371 ! regulation of protein modification process GO:0031399 79 78 1,000 0,10614647 0,13993415 ! microtubule-based movement GO:0007018 82 78 1,000 0,10614647 0,13983412 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,10614647 0,13973424 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,10817604 0,14230439 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,10817604 0,14220288 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,10817604 0,14210153 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,10817604 0,14200032 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,10817604 0,14189925 ! learning GO:0007612 16 16 0,000 0,10817604 0,14179832 ! circadian rhythm GO:0007623 16 16 0,000 0,10817604 0,14169754 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,10817604 0,14159691 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,10817604 0,14149641 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,10817604 0,14139606 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,10817604 0,14129585 ! vesicle targeting GO:0006903 17 16 0,000 0,10817604 0,14119578 ! segmentation GO:0035282 17 16 0,000 0,10817604 0,14109586 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,10817604 0,14099607 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,10817604 0,14089643 ! iron ion homeostasis GO:0055072 16 16 0,000 0,10817604 0,14079692 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,10817604 0,14069756 ! cell fate specification GO:0001708 16 16 0,000 0,10817604 0,14059834 ! pentose metabolic process GO:0019321 16 16 0,000 0,10817604 0,14049926 ! fatty acid transport GO:0015908 16 16 0,000 0,10817604 0,14040031 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,10817604 0,14030151 ! cofactor catabolic process GO:0051187 16 16 0,000 0,10817604 0,14020284 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,10817604 0,14010432 ! polyol metabolic process GO:0019751 16 16 0,000 0,10817604 0,14000593 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,10817604 0,13990768 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,10817604 0,13980957 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,10817604 0,13971159 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,10817604 0,13961376 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,10817604 0,13951606 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,10817604 0,13941849 ! regulation of coagulation GO:0050818 17 16 0,000 0,10817604 0,13932107 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,1145425 0,14741748 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,1145425 0,1473146 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,1145425 0,14721187 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,1145425 0,14710929 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,1145425 0,14700684 ! leukocyte adhesion GO:0007159 17 17 0,000 0,1145425 0,14690454 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,1145425 0,14680238 ! sensory perception of smell GO:0007608 17 17 0,000 0,1145425 0,14670037 ! glucose transport GO:0015758 17 17 0,000 0,1145425 0,14659849 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,1145425 0,14649676 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,1145425 0,14639517 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,1145425 0,14629371 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,1145425 0,1461924 ! neural crest cell development GO:0014032 19 17 0,000 0,1145425 0,14609123 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,1145425 0,1459902 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,1145425 0,14588931 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,1145425 0,14578856 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,1145425 0,14568794 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,1145425 0,14558747 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,1145425 0,14548713 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,1145425 0,14538693 ! adult locomotory behavior GO:0008344 17 17 0,000 0,1145425 0,14528687 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,1145425 0,14518695 ! liver development GO:0001889 17 17 0,000 0,1145425 0,14508717 ! gene silencing GO:0016458 17 17 0,000 0,1145425 0,14498752 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,12086443 0,1528848 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,12086443 0,15277994 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,12086443 0,15267522 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,12086443 0,15257065 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,12086443 0,15246622 ! membrane docking GO:0022406 18 18 0,000 0,12086443 0,15236193 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,12086443 0,15225779 ! response to calcium ion GO:0051592 18 18 0,000 0,12086443 0,15215379 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,12086443 0,15204993 ! hexose transport GO:0008645 18 18 0,000 0,12086443 0,15194621 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,12086443 0,15184264 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,12086443 0,1517392 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,12086443 0,15163591 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,12086443 0,15153275 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,12086443 0,15142974 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,12086443 0,15132687 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,12086443 0,15122413 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,12086443 0,15112154 ! BMP signaling pathway GO:0030509 18 18 0,000 0,12086443 0,15101908 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,12086443 0,15091677 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,12086443 0,15081459 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,12086443 0,15071255 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,12237145 0,15248856 ! positive regulation of protein kinase activity GO:0045860 89 86 1,000 0,12473777 0,15533223 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,12714214 0,15821942 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,12714214 0,15811266 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,12714214 0,15800605 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,12714214 0,15789957 ! feeding behavior GO:0007631 19 19 0,000 0,12714214 0,15779324 ! peroxisome organization GO:0007031 19 19 0,000 0,12714214 0,15768706 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,12714214 0,15758101 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,12714214 0,15747511 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,12714214 0,15736935 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,12714214 0,15726374 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,12714214 0,15715826 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,12714214 0,15705293 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,12714214 0,15694773 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,12714214 0,15684268 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,12714214 0,15673777 ! eye morphogenesis GO:0048592 19 19 0,000 0,12714214 0,156633 ! vesicle localization GO:0051648 20 19 0,000 0,12714214 0,15652837 ! male gamete generation GO:0048232 90 88 1,000 0,12950396 0,15932964 GO:0007283|spermatogenesis, ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,13337593 0,16398388 ! organic ether metabolic process GO:0018904 20 20 0,000 0,13337593 0,16387456 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,13337593 0,16376538 ! neural tube development GO:0021915 21 20 0,000 0,13337593 0,16365635 ! phagocytosis GO:0006909 21 20 0,000 0,13337593 0,16354747 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,13337593 0,16343872 ! protein targeting to membrane GO:0006612 22 20 0,000 0,13337593 0,16333013 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,13337593 0,16322167 ! chromatin remodeling GO:0006338 20 20 0,000 0,13337593 0,16311337 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,13337593 0,1630052 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,13337593 0,16289718 ! lipid oxidation GO:0034440 20 20 0,000 0,13337593 0,1627893 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,13337593 0,16268156 ! RNA modification GO:0009451 20 20 0,000 0,13337593 0,16257397 ! single fertilization GO:0007338 21 20 0,000 0,13337593 0,16246652 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,13431311 0,16350004 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,13916309 0,16929212 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,1395661 0,1696704 ! mRNA catabolic process GO:0006402 21 21 0,000 0,1395661 0,16955856 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,1395661 0,16944686 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,1395661 0,16933531 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,1395661 0,1692239 ! ear morphogenesis GO:0042471 21 21 0,000 0,1395661 0,16911264 ! organic anion transport GO:0015711 21 21 0,000 0,1395661 0,16900153 ! cholesterol transport GO:0030301 21 21 0,000 0,1395661 0,16889056 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,1395661 0,16877974 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,1395661 0,16866907 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,1395661 0,16855854 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,1395661 0,16844815 ! regulation of proteolysis GO:0030162 21 21 0,000 0,1395661 0,16833791 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,1395661 0,16822782 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,1395661 0,16811786 ! regulation of response to stress GO:0080134 97 94 1,000 0,14405184 0,17340793 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,14571296 0,17529307 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,14571296 0,17517872 ! sister chromatid segregation GO:0000819 22 22 0,000 0,14571296 0,17506452 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,14571296 0,17495047 ! regulation of ion transport GO:0043269 22 22 0,000 0,14571296 0,17483657 ! odontogenesis GO:0042476 22 22 0,000 0,14571296 0,17472282 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,14571296 0,17460922 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 0,000 0,14571296 0,17449576 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,14571296 0,17438245 ! spindle organization GO:0007051 22 22 0,000 0,14571296 0,17426929 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,14571296 0,17415628 ! cell chemotaxis GO:0060326 23 22 0,000 0,14571296 0,17404341 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,14571296 0,17393069 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,14571296 0,17381811 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,14571296 0,17370568 ! detection of external stimulus GO:0009581 23 22 0,000 0,14571296 0,17359339 ! neuron migration GO:0001764 22 22 0,000 0,14571296 0,17348125 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,14571296 0,17336926 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,14571296 0,17325741 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,14571296 0,1731457 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,14571296 0,17303414 ! aerobic respiration GO:0009060 22 22 0,000 0,14571296 0,17292272 ! cytokine production GO:0001816 22 22 0,000 0,14571296 0,17281144 ! cytokinesis GO:0000910 23 22 0,000 0,14571296 0,17270031 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,14571296 0,17258932 ! viral infectious cycle GO:0019058 23 23 0,000 0,15181679 0,17970349 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,15181679 0,17958815 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,15181679 0,17947295 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,15181679 0,17935791 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,15181679 0,17924301 ! endocrine system development GO:0035270 23 23 0,000 0,15181679 0,17912826 ! lipid homeostasis GO:0055088 23 23 0,000 0,15181679 0,17901365 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,15181679 0,17889919 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,15181679 0,17878488 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,15181679 0,17867071 ! endocytosis GO:0006897 99 98 1,000 0,15393767 0,18105113 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,15393767 0,18093566 ! gliogenesis GO:0042063 24 24 0,000 0,15787789 0,18544866 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,15787789 0,18533054 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,15787789 0,18521257 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,15787789 0,18509475 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,15787789 0,18497708 ! fertilization GO:0009566 25 24 0,000 0,15787789 0,18485956 ! maintenance of protein location GO:0045185 25 24 0,000 0,15787789 0,18474219 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,15787789 0,18462497 ! glucan metabolic process GO:0044042 25 24 0,000 0,15787789 0,18450789 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! response to other organism GO:0051707 101 100 1,000 0,15893085 0,18562076 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,16389656 0,19129915 ! negative regulation of secretion GO:0051048 26 25 0,000 0,16389656 0,19117807 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,16389656 0,19105715 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,16389656 0,19093638 ! endosome transport GO:0016197 25 25 0,000 0,16389656 0,19081576 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,16389656 0,1906953 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,16389656 0,19057499 ! excretion GO:0007588 25 25 0,000 0,16389656 0,19045482 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,16389656 0,19033482 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,16389656 0,19021496 ! gastrulation GO:0007369 25 25 0,000 0,16389656 0,19009525 ! heart morphogenesis GO:0003007 25 25 0,000 0,16389656 0,18997569 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,16389656 0,18985629 ! regulation of endocytosis GO:0030100 25 25 0,000 0,16389656 0,18973703 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,16389656 0,18961792 ! positive regulation of binding GO:0051099 27 26 0,000 0,16987308 0,19640909 ! positive regulation of defense response GO:0031349 26 26 0,000 0,16987308 0,19628595 ! glycolysis GO:0006096 26 26 0,000 0,16987308 0,19616296 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,16987308 0,19604013 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,16987308 0,19591745 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,16987308 0,19579492 ! cellular defense response GO:0006968 26 26 0,000 0,16987308 0,19567255 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,16987308 0,19555033 ! regulation of protein secretion GO:0050708 26 26 0,000 0,16987308 0,19542827 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,16987308 0,19530635 GO:0035150|regulation of tube size, ! response to insulin stimulus GO:0032868 28 26 0,000 0,16987308 0,19518459 ! maintenance of location in cell GO:0051651 27 26 0,000 0,16987308 0,19506298 ! chloride transport GO:0006821 27 27 0,000 0,17580775 0,20175198 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,17580775 0,20162643 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,17580775 0,20150104 ! learning or memory GO:0007611 28 27 0,000 0,17580775 0,20137581 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,17580775 0,20125073 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,17580775 0,20112581 ! peptide metabolic process GO:0006518 29 27 0,000 0,17580775 0,20100104 ! inner ear development GO:0048839 27 27 0,000 0,17580775 0,20087643 ! defense response to bacterium GO:0042742 27 27 0,000 0,17580775 0,20075197 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,17580775 0,20062767 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,17580775 0,20050351 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,18170085 0,20709627 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,18170085 0,20696827 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,18170085 0,20684043 ! carbohydrate transport GO:0008643 28 28 0,000 0,18170085 0,20671276 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,18170085 0,20658523 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,18170085 0,20645787 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,18170085 0,20633066 ! histone modification GO:0016570 28 28 0,000 0,18170085 0,20620361 ! cartilage development GO:0051216 29 28 0,000 0,18170085 0,20607672 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,18755267 0,21258276 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,18755267 0,2124521 ! viral reproductive process GO:0022415 29 29 0,000 0,18755267 0,2123216 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,18755267 0,21219126 ! leukocyte migration GO:0050900 30 29 0,000 0,18755267 0,21206108 ! antigen processing and presentation GO:0019882 29 29 0,000 0,18755267 0,21193106 ! tRNA processing GO:0008033 29 29 0,000 0,18755267 0,2118012 ! covalent chromatin modification GO:0016569 29 29 0,000 0,18755267 0,2116715 ! adult behavior GO:0030534 30 29 0,000 0,18755267 0,21154196 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,18755267 0,21141258 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,18755267 0,21128335 ! transition metal ion transport GO:0000041 31 30 0,000 0,19336349 0,21769634 ! RNA catabolic process GO:0006401 30 30 0,000 0,19336349 0,21756343 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,19336349 0,21743069 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,19336349 0,21729811 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,19336349 0,21716569 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,19336349 0,21703344 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,19336349 0,21690134 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,19336349 0,21676941 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,19336349 0,21663763 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,19336349 0,21650602 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,19336349 0,21637456 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,19336349 0,21624327 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,19336349 0,21611213 ! regulation of translational initiation GO:0006446 31 31 0,000 0,19913359 0,22242618 ! membrane fusion GO:0006944 31 31 0,000 0,19913359 0,22229146 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,19913359 0,2221569 ! ion transmembrane transport GO:0034220 31 31 0,000 0,19913359 0,2220225 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,19913359 0,22188827 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,19913359 0,2217542 ! regulation of heart contraction GO:0008016 31 31 0,000 0,19913359 0,22162029 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,19913359 0,22148654 ! camera-type eye development GO:0043010 31 31 0,000 0,19913359 0,22135296 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,19913359 0,22121953 ! glucose catabolic process GO:0006007 32 32 0,000 0,20486325 0,22744757 ! lipid modification GO:0030258 32 32 0,000 0,20486325 0,22731064 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,20486325 0,22717387 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,20486325 0,22703726 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,20486325 0,22690082 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,20486325 0,22676454 ! nuclear export GO:0051168 32 32 0,000 0,20486325 0,22662843 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,20486325 0,22649248 ! maintenance of location GO:0051235 33 32 0,000 0,20486325 0,22635669 ! amino acid transport GO:0006865 33 33 0,000 0,21055275 0,23250372 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,21055275 0,2323645 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,21055275 0,23222544 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,21055275 0,23208655 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,21055275 0,23194783 ! regulation of actin filament length GO:0030832 34 34 0,000 0,21620236 0,23802925 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,21620236 0,23788714 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,21620236 0,2377452 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,21620236 0,23760343 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,21620236 0,23746183 ! viral reproduction GO:0016032 34 34 0,000 0,21620236 0,2373204 ! detection of stimulus GO:0051606 36 34 0,000 0,21620236 0,23717914 ! acute inflammatory response GO:0002526 35 35 0,000 0,22181237 0,24318869 ! regulation of cellular component size GO:0032535 35 35 0,000 0,22181237 0,24304411 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,22181237 0,2428997 ! mesoderm development GO:0007498 35 35 0,000 0,22181237 0,24275546 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,22181237 0,24261139 ! inorganic anion transport GO:0015698 35 35 0,000 0,22181237 0,24246749 ! regulation of immune effector process GO:0002697 35 35 0,000 0,22181237 0,24232377 ! hydrogen transport GO:0006818 36 36 0,000 0,22738303 0,2482624 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,22738303 0,24811541 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,22738303 0,2479686 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,22738303 0,24782196 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,22738303 0,24767549 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,22738303 0,24752919 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,22738303 0,24738307 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,22738303 0,24723712 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,22738303 0,24709135 ! regulation of lipase activity GO:0060191 36 36 0,000 0,22738303 0,24694574 ! activation of immune response GO:0002253 36 36 0,000 0,22738303 0,24680031 ! coagulation GO:0050817 39 36 0,000 0,22738303 0,24665505 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,23291463 0,25250686 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,23291463 0,25235841 ! eye development GO:0001654 37 37 0,000 0,23291463 0,25221014 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,23291463 0,25206204 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,23291463 0,25191412 ! positive regulation of secretion GO:0051047 39 38 0,000 0,23840742 0,25770374 ! neurotransmitter transport GO:0006836 40 38 0,000 0,23840742 0,25755268 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,23840742 0,2574018 ! exocytosis GO:0006887 40 38 0,000 0,23840742 0,2572511 ! hexose catabolic process GO:0019320 38 38 0,000 0,23840742 0,25710057 ! RNA elongation GO:0006354 38 38 0,000 0,23840742 0,25695022 ! regulation of neurological system process GO:0031644 38 38 0,000 0,23840742 0,25680004 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,24386168 0,26252165 ! hemostasis GO:0007599 42 39 0,000 0,24386168 0,2623684 ! activation of MAPK activity GO:0000187 39 39 0,000 0,24386168 0,26221533 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,24386168 0,26206243 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,24386168 0,26190972 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,24386168 0,26175718 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,24386168 0,26160481 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,24386168 0,26145263 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,24386168 0,26130062 ! limb development GO:0060173 39 39 0,000 0,24386168 0,26114879 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,24927767 0,26679369 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,25465565 0,27239139 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,25465565 0,27223339 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,25465565 0,27207557 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,25465565 0,27191794 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,25465565 0,27176049 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,25465565 0,27160322 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,25465565 0,27144613 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,25999588 0,27697827 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,25999588 0,27681826 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,25999588 0,27665844 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,25999588 0,2764988 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,26529863 0,28197542 ! alcohol catabolic process GO:0046164 43 43 0,000 0,26529863 0,2818129 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,26529863 0,28165056 ! mRNA transport GO:0051028 44 44 0,000 0,27056415 0,28707527 ! vitamin metabolic process GO:0006766 44 44 0,000 0,27056415 0,28691009 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,27056415 0,2867451 ! amine biosynthetic process GO:0009309 46 45 0,000 0,2757927 0,29211836 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,2757927 0,29195057 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,2757927 0,29178298 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,2757927 0,29161558 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,2757927 0,29144837 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,28098453 0,29676475 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,28098453 0,29659478 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,28098453 0,29642501 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,2861399 0,30169098 ! amine transport GO:0015837 47 47 0,000 0,2861399 0,30151848 ! calcium ion transport GO:0006816 48 48 0,000 0,29125905 0,30673738 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,29125905 0,3065622 ! ossification GO:0001503 50 49 0,000 0,29634223 0,31173443 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,29634223 0,3115566 ! divalent metal ion transport GO:0070838 49 49 0,000 0,29634223 0,31137898 ! response to bacterium GO:0009617 50 49 0,000 0,29634223 0,31120155 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,29634223 0,31102433 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,29634223 0,31084731 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,30138969 0,315962 ! chromatin assembly GO:0031497 50 50 0,000 0,30138969 0,31578238 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,30138969 0,31560296 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,30138969 0,31542374 ! transcription initiation GO:0006352 50 50 0,000 0,30138969 0,31524472 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,30138969 0,31506591 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,30640168 0,32012376 ! positive regulation of immune response GO:0050778 51 51 0,000 0,30640168 0,31994238 ! rRNA metabolic process GO:0016072 51 51 0,000 0,30640168 0,31976121 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,30640168 0,31958025 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,30640168 0,31939949 ! RNA localization GO:0006403 52 52 0,000 0,31137845 0,32440389 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,31137845 0,32422061 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,31137845 0,32403754 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,31137845 0,32385467 ! sodium ion transport GO:0006814 53 53 0,000 0,31632023 0,3288089 ! tRNA metabolic process GO:0006399 53 53 0,000 0,31632023 0,32862355 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,31632023 0,32843841 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,31632023 0,32825348 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,31632023 0,32806875 ! sulfur metabolic process GO:0006790 55 54 0,000 0,32122726 0,33297066 ! nucleosome organization GO:0034728 55 55 0,000 0,32609978 0,33783131 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,32609978 0,33764152 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,33093804 0,34245863 ! ATP metabolic process GO:0046034 57 57 0,000 0,33574227 0,34723513 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,33574227 0,34704038 ! innate immune response GO:0045087 58 58 0,000 0,3405127 0,35177405 ! carboxylic acid transport GO:0046942 59 59 0,000 0,34524956 0,35646775 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,34524956 0,35626816 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,34524956 0,35606879 ! potassium ion transport GO:0006813 60 60 0,000 0,34995309 0,36071786 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,34995309 0,36051623 ! cellular respiration GO:0045333 62 61 0,000 0,35462351 0,36512354 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,35462351 0,36491967 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,35462351 0,36471603 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,35926106 0,3692795 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,35926106 0,36907365 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,35926106 0,36886804 ! regulation of secretion GO:0051046 65 63 0,000 0,36386596 0,37338807 ! glucose metabolic process GO:0006006 63 63 0,000 0,36386596 0,37318028 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,36386596 0,37297273 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,36386596 0,37276541 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,36843844 0,37724002 ! anion transport GO:0006820 65 65 0,000 0,37297871 0,38167672 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,37748701 0,38607578 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,37748701 0,38586165 ! DNA packaging GO:0006323 66 66 0,000 0,37748701 0,38564776 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,37748701 0,3854341 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,37748701 0,38522069 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,38196355 0,38957323 ! muscle contraction GO:0006936 67 67 0,000 0,38196355 0,38935775 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,38196355 0,38914252 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,38640855 0,39345357 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,38640855 0,39323631 ! regionalization GO:0003002 70 69 0,000 0,39082223 0,39750848 ! positive regulation of transport GO:0051050 71 70 0,000 0,3952048 0,40174432 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,3952048 0,40152285 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,39955649 0,40572044 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,39955649 0,40549703 ! ribosome biogenesis GO:0042254 71 71 0,000 0,39955649 0,40527386 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,39955649 0,40505094 ! secretion by cell GO:0032940 75 72 0,000 0,40387749 0,40920628 ! muscle system process GO:0003012 72 72 0,000 0,40387749 0,40898144 ! regulation of cytokine production GO:0001817 72 72 0,000 0,40387749 0,40875685 ! electron transport chain GO:0022900 75 74 0,000 0,41242832 0,41718188 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,41242832 0,41695304 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,41665856 0,42099875 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,41665856 0,42076807 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,42085896 0,42477714 ! regulation of immune response GO:0050776 78 78 0,000 0,42917107 0,43292955 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,43736628 0,44095517 ! MAPKKK cascade GO:0000165 82 81 0,000 0,44142055 0,44479939 ! lipid catabolic process GO:0016042 82 81 0,000 0,44142055 0,44455633 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,44944343 0,45238899 ! ncRNA processing GO:0034470 83 83 0,000 0,44944343 0,45214205 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,45341242 0,45588603 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,46126651 0,46353009 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,46126651 0,46327748 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,46901002 0,47079818 ! chemotaxis GO:0006935 90 89 0,000 0,47284077 0,47438516 GO:0042330|taxis, ! visual perception GO:0007601 93 92 0,000 0,48417134 0,48548845 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,48417134 0,48522446 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,48417134 0,48496075 ! pattern specification process GO:0007389 96 94 0,000 0,49159215 0,4921262 ! cofactor metabolic process GO:0051186 95 94 0,000 0,49159215 0,49185903 ! regulation of system process GO:0044057 98 98 0,000 0,50612138 0,50612138