pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6557-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! elastic fiber assembly GO:0048251 15 9 6,000 8,473E-16 2,039E-12 ! collagen metabolic process GO:0032963 45 31 7,000 7,031E-13 8,459E-10 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 7,000 1,601E-12 1,284E-09 ! multicellular organismal metabolic process GO:0044236 57 40 7,000 6,636E-12 3,991E-09 ! aging GO:0007568 103 55 7,000 9,953E-11 4,789E-08 ! extracellular matrix organization GO:0030198 133 66 7,000 4,512E-10 1,809E-07 ! hormone-mediated signaling GO:0009755 74 41 6,000 4,719E-10 1,622E-07 ! release of cytochrome c from mitochondria GO:0001836 30 14 4,000 2,691E-09 8,093E-07 ! DNA damage response, signal transduction GO:0042770 128 60 6,000 7,574E-09 2,025E-06 ! interphase of mitotic cell cycle GO:0051329 209 95 7,000 8,602E-09 2,07E-06 ! regulation of DNA metabolic process GO:0051052 178 97 7,000 1,015E-08 2,221E-06 ! interphase GO:0051325 213 98 7,000 1,102E-08 2,209E-06 ! regulation of lipid kinase activity GO:0043550 13 7 3,000 1,148E-08 2,125E-06 ! apoptotic mitochondrial changes GO:0008637 41 20 4,000 2,041E-08 3,508E-06 ! cell cycle checkpoint GO:0000075 137 69 6,000 2,049E-08 3,286E-06 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 4,085E-08 6,143E-06 ! cellular response to hormone stimulus GO:0032870 167 82 6,000 6,892E-08 9,754E-06 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 4,000 1,037E-07 1,387E-05 ! response to UV GO:0009411 104 53 5,000 1,119E-07 1,418E-05 ! gland development GO:0048732 206 88 6,000 1,126E-07 1,355E-05 ! response to protein stimulus GO:0051789 149 91 6,000 1,421E-07 1,628E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 1,745E-07 1,908E-05 ! double-strand break repair via homologous recombination GO:0000724 19 13 3,000 2,299E-07 2,405E-05 GO:0000725|recombinational repair, ! DNA damage checkpoint GO:0000077 71 33 4,000 2,987E-07 2,995E-05 ! response to gamma radiation GO:0010332 28 14 3,000 3,208E-07 3,088E-05 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 4,000 4,058E-07 3,755E-05 ! DNA integrity checkpoint GO:0031570 75 36 4,000 4,696E-07 4,185E-05 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 7,809E-07 6,71E-05 ! peptidyl-threonine phosphorylation GO:0018107 20 5 2,000 7,809E-07 6,479E-05 ! B cell homeostasis GO:0001782 13 5 2,000 7,809E-07 6,263E-05 ! double-strand break repair GO:0006302 81 44 4,000 1,316E-06 1,021E-04 ! nuclear migration GO:0007097 12 6 2,000 1,557E-06 1,171E-04 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 2,000 1,557E-06 1,135E-04 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,557E-06 1,102E-04 GO:0031272|regulation of pseudopodium assembly, ! reciprocal meiotic recombination GO:0007131 39 21 3,000 1,874E-06 1,288E-04 ! cell aging GO:0007569 44 21 3,000 1,874E-06 1,252E-04 ! response to unfolded protein GO:0006986 131 85 5,000 1,905E-06 1,239E-04 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 3,000 2,283E-06 1,445E-04 ! prostate gland development GO:0030850 13 7 2,000 2,716E-06 1,676E-04 ! macrophage differentiation GO:0030225 11 7 2,000 2,716E-06 1,634E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 2,716E-06 1,594E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 2,716E-06 1,556E-04 ! peptidyl-threonine modification GO:0018210 25 7 2,000 2,716E-06 1,52E-04 ! response to estrogen stimulus GO:0043627 93 51 4,000 2,778E-06 1,519E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 3,908E-06 2,089E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 3,000 3,908E-06 2,044E-04 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 3,908E-06 2E-04 ! ER overload response GO:0006983 12 8 2,000 4,332E-06 2,171E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 4,332E-06 2,127E-04 ! cell cycle arrest GO:0007050 213 100 5,000 4,925E-06 2,37E-04 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 6,262E-06 2,954E-04 ! regulation of homeostatic process GO:0032844 134 62 4,000 7,368E-06 3,409E-04 ! regulation of lipid metabolic process GO:0019216 115 63 4,000 7,976E-06 3,621E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 9,224E-06 4,11E-04 ! protein sumoylation GO:0016925 15 10 2,000 9,224E-06 4,035E-04 ! oocyte development GO:0048599 17 10 2,000 9,224E-06 3,963E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 1,081E-05 4,562E-04 ! response to ionizing radiation GO:0010212 65 32 3,000 1,085E-05 4,502E-04 ! negative regulation of kinase activity GO:0033673 131 68 4,000 1,163E-05 4,741E-04 ! oocyte differentiation GO:0009994 18 11 2,000 1,264E-05 5,07E-04 ! nucleus localization GO:0051647 19 11 2,000 1,264E-05 4,987E-04 ! reproductive structure development GO:0048608 113 71 4,000 1,437E-05 5,577E-04 ! negative regulation of transferase activity GO:0051348 140 72 4,000 1,539E-05 5,878E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,68E-05 6,317E-04 ! T cell homeostasis GO:0043029 25 12 2,000 1,68E-05 6,22E-04 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 1,68E-05 6,126E-04 GO:0042130|negative regulation of T cell proliferation, ! meiosis GO:0007126 121 74 4,000 1,76E-05 6,32E-04 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 4,000 1,879E-05 6,649E-04 ! meiosis I GO:0007127 65 37 3,000 1,96E-05 6,834E-04 ! response to X-ray GO:0010165 25 13 2,000 2,178E-05 7,485E-04 ! response to steroid hormone stimulus GO:0048545 137 78 4,000 2,275E-05 7,709E-04 ! response to drug GO:0042493 143 82 4,000 2,9E-05 9,69E-04 ! response to nutrient GO:0007584 125 82 4,000 2,9E-05 9,557E-04 ! response to reactive oxygen species GO:0000302 67 42 3,000 3,267E-05 1,062E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 3,442E-05 1,104E-03 ! lymphocyte homeostasis GO:0002260 30 15 2,000 3,442E-05 1,09E-03 ! mitochondrion organization GO:0007005 148 86 4,000 3,651E-05 1,141E-03 ! JAK-STAT cascade GO:0007259 71 44 3,000 3,936E-05 1,214E-03 ! filopodium assembly GO:0046847 32 16 2,000 4,224E-05 1,286E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 4,224E-05 1,27E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 4,224E-05 1,255E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 4,224E-05 1,239E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of cell cycle process GO:0010564 149 90 4,000 4,544E-05 1,317E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 4,699E-05 1,346E-03 ! pigmentation GO:0043473 100 46 3,000 4,699E-05 1,33E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 5,112E-05 1,43E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 5,112E-05 1,414E-03 ! microspike assembly GO:0030035 36 17 2,000 5,112E-05 1,398E-03 ! centrosome cycle GO:0007098 25 18 2,000 6,115E-05 1,653E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 6,115E-05 1,635E-03 ! leukocyte differentiation GO:0002521 202 96 4,000 6,19E-05 1,637E-03 ! cellular response to unfolded protein GO:0034620 33 19 2,000 7,239E-05 1,893E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! cellular pigmentation GO:0033059 36 19 2,000 7,239E-05 1,873E-03 ! G1 phase GO:0051318 40 19 2,000 7,239E-05 1,853E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 7,239E-05 1,833E-03 ! response to alkaloid GO:0043279 38 20 2,000 8,49E-05 2,128E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 8,49E-05 2,106E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 8,49E-05 2,084E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 9,874E-05 2,4E-03 ! oogenesis GO:0048477 36 21 2,000 9,874E-05 2,376E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 9,874E-05 2,352E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 1,023E-04 2,413E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 1,14E-04 2,662E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 1,306E-04 3,022E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 1,306E-04 2,994E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 1,488E-04 3,378E-03 ! leukocyte homeostasis GO:0001776 44 24 2,000 1,488E-04 3,347E-03 ! vasculogenesis GO:0001570 46 25 2,000 1,686E-04 3,756E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 1,686E-04 3,722E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 1,83E-04 4,003E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,833E-04 3,974E-03 ! Notch receptor processing GO:0007220 8 5 1,000 1,833E-04 3,938E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,833E-04 3,903E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,833E-04 3,869E-03 ! mRNA transcription GO:0009299 9 5 1,000 1,833E-04 3,836E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 1,833E-04 3,802E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,833E-04 3,77E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 1,833E-04 3,738E-03 ! decidualization GO:0046697 11 5 1,000 1,833E-04 3,707E-03 ! histone demethylation GO:0016577 10 5 1,000 1,833E-04 3,676E-03 ! mitotic recombination GO:0006312 9 5 1,000 1,833E-04 3,645E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 1,833E-04 3,615E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 1,833E-04 3,586E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,833E-04 3,557E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,833E-04 3,529E-03 ! microtubule organizing center organization GO:0031023 39 26 2,000 1,9E-04 3,628E-03 GO:0051297|centrosome organization, ! blastocyst development GO:0001824 49 26 2,000 1,9E-04 3,599E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 2,058E-04 3,869E-03 ! homeostasis of number of cells GO:0048872 114 67 3,000 2,058E-04 3,839E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 2,131E-04 3,943E-03 ! mitochondrial membrane organization GO:0007006 57 27 2,000 2,131E-04 3,913E-03 ! response to toxin GO:0009636 47 27 2,000 2,131E-04 3,884E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 2,131E-04 3,855E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 2,306E-04 4,14E-03 ! urogenital system development GO:0001655 137 69 3,000 2,306E-04 4,11E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 2,645E-04 4,679E-03 ! response to organic cyclic substance GO:0014070 55 29 2,000 2,645E-04 4,645E-03 ! tissue homeostasis GO:0001894 48 29 2,000 2,645E-04 4,612E-03 GO:0048871|multicellular organismal homeostasis, ! positive regulation of DNA repair GO:0045739 9 6 1,000 2,742E-04 4,746E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 2,742E-04 4,713E-03 ! male meiosis GO:0007140 7 6 1,000 2,742E-04 4,679E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 2,742E-04 4,646E-03 ! protein amino acid dealkylation GO:0008214 12 6 1,000 2,742E-04 4,614E-03 GO:0006482|protein amino acid demethylation, ! protein lipoylation GO:0009249 10 6 1,000 2,742E-04 4,582E-03 ! neuron apoptosis GO:0051402 9 6 1,000 2,742E-04 4,55E-03 ! neural nucleus development GO:0048857 14 6 1,000 2,742E-04 4,519E-03 ! response to UV-C GO:0010225 11 6 1,000 2,742E-04 4,488E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 2,742E-04 4,458E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 2,742E-04 4,428E-03 ! G2 phase GO:0051319 16 6 1,000 2,742E-04 4,398E-03 GO:0000085|G2 phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,742E-04 4,369E-03 ! maternal placenta development GO:0001893 12 6 1,000 2,742E-04 4,341E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 2,742E-04 4,312E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 2,93E-04 4,577E-03 ! response to hydrogen peroxide GO:0042542 50 32 2,000 3,557E-04 5,521E-03 ! positive regulation of protein ubiquitination GO:0031398 12 7 1,000 3,828E-04 5,904E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 3,828E-04 5,867E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 3,828E-04 5,829E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,828E-04 5,793E-03 ! mRNA stabilization GO:0048255 18 7 1,000 3,828E-04 5,757E-03 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 3,828E-04 5,721E-03 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 3,828E-04 5,685E-03 ! protein-cofactor linkage GO:0018065 13 7 1,000 3,828E-04 5,651E-03 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 3,828E-04 5,616E-03 ! organ growth GO:0035265 15 7 1,000 3,828E-04 5,582E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 3,828E-04 5,548E-03 ! centrosome duplication GO:0051298 13 7 1,000 3,828E-04 5,515E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 3,828E-04 5,482E-03 ! response to tumor cell GO:0002347 13 7 1,000 3,828E-04 5,45E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 3,828E-04 5,418E-03 ! negative regulation of protein transport GO:0051224 69 33 2,000 3,9E-04 5,487E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 4,649E-04 6,503E-03 ! female gonad development GO:0008585 58 35 2,000 4,649E-04 6,466E-03 ! negative regulation of growth GO:0045926 155 84 3,000 4,896E-04 6,77E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 5,056E-04 6,951E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 5,056E-04 6,911E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 5,09E-04 6,919E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 5,09E-04 6,88E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 5,09E-04 6,841E-03 ! pigment granule organization GO:0048753 16 8 1,000 5,09E-04 6,803E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 5,09E-04 6,766E-03 ! regulation of pigmentation during development GO:0048070 24 8 1,000 5,09E-04 6,729E-03 ! melanin metabolic process GO:0006582 15 8 1,000 5,09E-04 6,692E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 5,09E-04 6,655E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 5,09E-04 6,619E-03 ! response to UV-B GO:0010224 16 8 1,000 5,09E-04 6,584E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 5,09E-04 6,549E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 5,09E-04 6,514E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,09E-04 6,479E-03 ! blastocyst growth GO:0001832 19 8 1,000 5,09E-04 6,445E-03 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 5,09E-04 6,411E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 5,09E-04 6,378E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 5,485E-04 6,837E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 5,936E-04 7,362E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 5,936E-04 7,324E-03 ! development of primary female sexual characteristics GO:0046545 67 38 2,000 5,936E-04 7,287E-03 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 2,000 5,936E-04 7,25E-03 ! regulation of cell adhesion GO:0030155 212 89 3,000 6,094E-04 7,405E-03 ! sex differentiation GO:0007548 145 90 3,000 6,356E-04 7,685E-03 ! mammary gland development GO:0030879 86 39 2,000 6,41E-04 7,712E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 6,525E-04 7,811E-03 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 6,525E-04 7,772E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 6,525E-04 7,734E-03 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 6,525E-04 7,696E-03 ! T cell selection GO:0045058 23 9 1,000 6,525E-04 7,659E-03 ! behavioral fear response GO:0001662 22 9 1,000 6,525E-04 7,621E-03 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 6,525E-04 7,585E-03 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 6,525E-04 7,548E-03 ! response to amine stimulus GO:0014075 13 9 1,000 6,525E-04 7,512E-03 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 6,525E-04 7,476E-03 ! postreplication repair GO:0006301 22 9 1,000 6,525E-04 7,441E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 6,525E-04 7,406E-03 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 6,525E-04 7,371E-03 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 6,525E-04 7,337E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 6,525E-04 7,302E-03 ! regulation of T cell proliferation GO:0042129 71 41 2,000 7,43E-04 8,277E-03 ! T cell differentiation GO:0030217 81 41 2,000 7,43E-04 8,238E-03 ! female gamete generation GO:0007292 61 41 2,000 7,43E-04 8,201E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 7,977E-04 8,764E-03 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 7,977E-04 8,724E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 8,134E-04 8,855E-03 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 8,134E-04 8,815E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 8,134E-04 8,776E-03 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 8,134E-04 8,736E-03 ! lung alveolus development GO:0048286 26 10 1,000 8,134E-04 8,698E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 8,134E-04 8,659E-03 ! B cell proliferation GO:0042100 18 10 1,000 8,134E-04 8,621E-03 ! multicellular organism growth GO:0035264 18 10 1,000 8,134E-04 8,583E-03 ! epithelial cell development GO:0002064 20 10 1,000 8,134E-04 8,546E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 8,134E-04 8,509E-03 ! alpha-beta T cell activation GO:0046631 23 10 1,000 8,134E-04 8,472E-03 ! apical protein localization GO:0045176 15 10 1,000 8,134E-04 8,435E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 8,134E-04 8,399E-03 ! blastocyst formation GO:0001825 17 10 1,000 8,134E-04 8,363E-03 ! response to nicotine GO:0035094 20 10 1,000 8,134E-04 8,328E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 8,134E-04 8,292E-03 ! regulation of protein localization GO:0032880 176 97 3,000 8,421E-04 8,549E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 8,548E-04 8,641E-03 ! B cell differentiation GO:0030183 107 44 2,000 9,145E-04 9,206E-03 ! developmental growth GO:0048589 82 44 2,000 9,145E-04 9,168E-03 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 9,767E-04 9,751E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 9,913E-04 9,856E-03 ! blood vessel remodeling GO:0001974 29 11 1,000 9,913E-04 9,815E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 9,913E-04 9,775E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 9,913E-04 9,735E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 9,913E-04 9,696E-03 ! negative regulation of ossification GO:0030279 26 11 1,000 9,913E-04 9,656E-03 ! nitric oxide metabolic process GO:0046209 15 11 1,000 9,913E-04 9,617E-03 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 1,000 9,913E-04 9,579E-03 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 9,913E-04 9,54E-03 ! thymus development GO:0048538 27 11 1,000 9,913E-04 9,502E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 9,913E-04 9,465E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,042E-03 9,905E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,179E-03 0,01117125 ! mitochondrial transport GO:0006839 82 48 2,000 1,179E-03 0,01112744 ! cellular component disassembly GO:0022411 86 48 2,000 1,179E-03 0,01108397 ! activation of caspase activity GO:0006919 84 48 2,000 1,179E-03 0,01104084 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,179E-03 0,01099805 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,186E-03 0,01101942 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 1,186E-03 0,01097704 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 35 12 1,000 1,186E-03 0,01093498 ! asymmetric protein localization GO:0008105 20 12 1,000 1,186E-03 0,01089324 ! membrane protein proteolysis GO:0033619 25 12 1,000 1,186E-03 0,01085182 GO:0006509|membrane protein ectodomain proteolysis, ! entry into host cell GO:0030260 32 12 1,000 1,186E-03 0,01081072 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 1,000 1,186E-03 0,01076992 ! mRNA polyadenylation GO:0006378 23 12 1,000 1,186E-03 0,01072943 ! gland morphogenesis GO:0022612 29 12 1,000 1,186E-03 0,01068925 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 1,186E-03 0,01064936 ! spleen development GO:0048536 22 12 1,000 1,186E-03 0,01060977 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,186E-03 0,01057048 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,186E-03 0,01053147 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 1,252E-03 0,01107747 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 1,252E-03 0,01103689 ! regulation of cell projection organization GO:0031344 121 50 2,000 1,328E-03 0,01166184 ! regulation of gene expression, epigenetic GO:0040029 105 50 2,000 1,328E-03 0,01161944 ! negative regulation of immune system process GO:0002683 95 50 2,000 1,328E-03 0,01157734 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 1,398E-03 0,0121423 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,398E-03 0,01209863 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,398E-03 0,01205526 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 1,398E-03 0,01201221 ! regulation of DNA repair GO:0006282 21 13 1,000 1,398E-03 0,01196946 ! regulation of cellular pH GO:0030641 22 13 1,000 1,398E-03 0,01192701 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,398E-03 0,01188487 ! mRNA 3'-end processing GO:0031124 24 13 1,000 1,398E-03 0,01184302 ! embryonic placenta development GO:0001892 23 13 1,000 1,398E-03 0,01180147 ! actin filament polymerization GO:0030041 24 13 1,000 1,398E-03 0,0117602 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,407E-03 0,01179237 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 2,000 1,407E-03 0,01175143 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 1,488E-03 0,0123888 ! cell maturation GO:0048469 100 53 2,000 1,572E-03 0,01304583 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 1,572E-03 0,013001 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,626E-03 0,01340037 ! regulation of S phase GO:0033261 23 14 1,000 1,626E-03 0,01335464 ! hair follicle morphogenesis GO:0031069 26 14 1,000 1,626E-03 0,01330922 ! RNA polyadenylation GO:0043631 30 14 1,000 1,626E-03 0,0132641 ! regulation of mRNA processing GO:0050684 24 14 1,000 1,626E-03 0,01321929 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 1,626E-03 0,01317478 GO:0060675|ureteric bud morphogenesis, ! bone mineralization GO:0030282 17 14 1,000 1,626E-03 0,01313057 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 1,626E-03 0,01308665 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 1,626E-03 0,01304303 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,626E-03 0,0129997 ! regulation of RNA stability GO:0043487 32 14 1,000 1,626E-03 0,01295665 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,75E-03 0,01389584 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 83 56 2,000 1,843E-03 0,01458827 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 1,871E-03 0,01476116 ! glycoprotein catabolic process GO:0006516 26 15 1,000 1,871E-03 0,01471292 ! pituitary gland development GO:0021983 29 15 1,000 1,871E-03 0,01466499 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,871E-03 0,01461738 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,871E-03 0,01457007 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 1,871E-03 0,01452307 ! regulation of bone remodeling GO:0046850 137 57 2,000 1,94E-03 0,015005 ! positive regulation of cell migration GO:0030335 126 57 2,000 1,94E-03 0,01495691 ! regulation of intracellular transport GO:0032386 101 57 2,000 1,94E-03 0,01490912 ! regulation of tissue remodeling GO:0034103 140 58 2,000 2,039E-03 0,01562321 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 2,133E-03 0,01628826 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 2,133E-03 0,01623671 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 2,133E-03 0,01618549 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 2,133E-03 0,01613459 ! biomineral formation GO:0031214 20 16 1,000 2,133E-03 0,01608402 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,133E-03 0,01603375 ! defense response to virus GO:0051607 37 16 1,000 2,133E-03 0,0159838 ! DNA catabolic process GO:0006308 86 59 2,000 2,141E-03 0,01600098 ! establishment of organelle localization GO:0051656 109 59 2,000 2,141E-03 0,01595145 ! regulation of protein complex assembly GO:0043254 117 61 2,000 2,356E-03 0,01749499 ! metencephalon development GO:0022037 30 17 1,000 2,41E-03 0,01784156 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,41E-03 0,01778683 ! endothelial cell migration GO:0043542 28 17 1,000 2,41E-03 0,01773244 ! regulation of viral genome replication GO:0045069 28 17 1,000 2,41E-03 0,01767838 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 2,41E-03 0,01762464 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,41E-03 0,01757123 ! regulation of protein binding GO:0043393 33 17 1,000 2,41E-03 0,01751815 ! DNA unwinding during replication GO:0006268 27 17 1,000 2,41E-03 0,01746538 ! RNA 3'-end processing GO:0031123 34 17 1,000 2,41E-03 0,01741293 ! ear development GO:0043583 103 62 2,000 2,468E-03 0,01777834 ! gonad development GO:0008406 98 62 2,000 2,468E-03 0,01772527 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,583E-03 0,01849811 ! multicellular organism reproduction GO:0032504 111 64 2,000 2,702E-03 0,01928976 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 2,000 2,702E-03 0,01923269 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 2,704E-03 0,01918858 ! epidermis morphogenesis GO:0048730 40 18 1,000 2,704E-03 0,01913214 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,704E-03 0,01907604 ! germ cell development GO:0007281 118 65 2,000 2,824E-03 0,01986517 ! actin filament organization GO:0007015 148 66 2,000 2,949E-03 0,0206856 ! developmental maturation GO:0021700 116 66 2,000 2,949E-03 0,02062547 ! cell projection assembly GO:0030031 120 66 2,000 2,949E-03 0,02056568 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 3,013E-03 0,02095296 ! neuromuscular junction development GO:0007528 34 19 1,000 3,013E-03 0,02089257 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 3,013E-03 0,02083254 ! regulation of cellular response to stress GO:0080135 128 67 2,000 3,078E-03 0,02121643 ! lung development GO:0030324 144 67 2,000 3,078E-03 0,02115581 ! chromosome segregation GO:0007059 113 67 2,000 3,078E-03 0,02109554 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 3,21E-03 0,02193773 ! DNA duplex unwinding GO:0032508 31 20 1,000 3,339E-03 0,0227551 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 1,000 3,339E-03 0,02269082 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 3,339E-03 0,0226269 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 3,339E-03 0,02256335 ! diencephalon development GO:0021536 34 20 1,000 3,339E-03 0,02250014 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 3,339E-03 0,02243729 ! respiratory tube development GO:0030323 150 70 2,000 3,484E-03 0,02334807 ! B cell activation GO:0042113 160 71 2,000 3,626E-03 0,0242345 ! ovarian follicle development GO:0001541 35 21 1,000 3,68E-03 0,02452376 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 3,68E-03 0,02445601 ! DNA modification GO:0006304 34 21 1,000 3,68E-03 0,02438864 ! positive regulation of locomotion GO:0040017 39 21 1,000 3,68E-03 0,02432164 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! response to cytokine stimulus GO:0034097 63 21 1,000 3,68E-03 0,024255 ! collagen catabolic process GO:0030574 28 21 1,000 3,68E-03 0,02418873 ! gut development GO:0048565 39 21 1,000 3,68E-03 0,02412282 ! regulation of caspase activity GO:0043281 122 72 2,000 3,772E-03 0,0246612 ! respiratory system development GO:0060541 153 72 2,000 3,772E-03 0,02459437 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 4,036E-03 0,02624585 ! regulation of chemotaxis GO:0050920 40 22 1,000 4,036E-03 0,02617511 ! regeneration GO:0031099 41 22 1,000 4,036E-03 0,02610474 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 4,036E-03 0,02603476 ! sensory perception of taste GO:0050909 28 22 1,000 4,036E-03 0,02596514 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,036E-03 0,0258959 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 4,036E-03 0,02582703 ! ureteric bud development GO:0001657 43 22 1,000 4,036E-03 0,02575853 ! renal system process GO:0003014 41 22 1,000 4,036E-03 0,02569038 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 4,036E-03 0,0256226 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 4,074E-03 0,02579655 ! organelle localization GO:0051640 136 74 2,000 4,074E-03 0,02572884 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 4,231E-03 0,02664732 ! lymphocyte differentiation GO:0030098 167 75 2,000 4,231E-03 0,02657774 ! development of primary sexual characteristics GO:0045137 124 76 2,000 4,391E-03 0,02751183 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 4,408E-03 0,02754774 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 4,408E-03 0,02747637 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 4,408E-03 0,02740538 ! response to ethanol GO:0045471 46 23 1,000 4,408E-03 0,02733474 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 4,408E-03 0,02726447 ! regulation of viral reproduction GO:0050792 38 23 1,000 4,408E-03 0,02719457 ! protein oligomerization GO:0051259 139 78 2,000 4,722E-03 0,02905717 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 4,795E-03 0,02943239 ! multicellular organismal response to stress GO:0033555 49 24 1,000 4,795E-03 0,0293575 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 4,795E-03 0,02928299 ! regulation of behavior GO:0050795 43 24 1,000 4,795E-03 0,02920885 ! lymphocyte proliferation GO:0046651 48 24 1,000 4,795E-03 0,02913509 ! protein tetramerization GO:0051262 52 24 1,000 4,795E-03 0,0290617 ! regulation of peptidase activity GO:0052547 134 79 2,000 4,893E-03 0,02958043 ! response to metal ion GO:0010038 140 80 2,000 5,068E-03 0,03056034 ! protein import into nucleus GO:0006606 158 80 2,000 5,068E-03 0,03048394 ! myelination GO:0042552 45 25 1,000 5,198E-03 0,03118574 ! response to starvation GO:0042594 42 25 1,000 5,198E-03 0,03110816 ! negative regulation of cell development GO:0010721 73 25 1,000 5,198E-03 0,03103097 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 5,198E-03 0,03095416 ! cellular response to nutrient levels GO:0031669 41 25 1,000 5,198E-03 0,03087773 ! T cell activation GO:0042110 168 81 2,000 5,247E-03 0,03109138 ! response to hypoxia GO:0001666 171 81 2,000 5,247E-03 0,03101498 ! nuclear import GO:0051170 161 81 2,000 5,247E-03 0,03093897 ! response to oxygen levels GO:0070482 176 83 2,000 5,615E-03 0,03302991 ! initiation of viral infection GO:0019059 57 26 1,000 5,615E-03 0,03295003 ! molting cycle process GO:0022404 50 26 1,000 5,615E-03 0,03286986 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 5,615E-03 0,03279007 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 5,615E-03 0,03271068 ! cellular response to oxidative stress GO:0034599 39 26 1,000 5,615E-03 0,03263167 ! response to estradiol stimulus GO:0032355 40 26 1,000 5,615E-03 0,03255304 ! leukocyte proliferation GO:0070661 52 26 1,000 5,615E-03 0,03247479 GO:0032943|mononuclear cell proliferation, ! negative regulation of transport GO:0051051 153 84 2,000 5,805E-03 0,03349147 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 6,047E-03 0,03480684 ! protein amino acid acylation GO:0043543 55 27 1,000 6,047E-03 0,03472377 ! fat cell differentiation GO:0045444 50 27 1,000 6,047E-03 0,03464109 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 6,047E-03 0,03455881 ! male gonad development GO:0008584 44 27 1,000 6,047E-03 0,03447692 ! base-excision repair GO:0006284 41 27 1,000 6,047E-03 0,03439541 ! regulation of chromosome organization GO:0033044 42 27 1,000 6,047E-03 0,03431429 ! response to inorganic substance GO:0010035 153 86 2,000 6,196E-03 0,03507504 ! tube morphogenesis GO:0035239 176 86 2,000 6,196E-03 0,03499271 ! protein localization in nucleus GO:0034504 176 87 2,000 6,397E-03 0,03604503 ! regulation of protein transport GO:0051223 154 87 2,000 6,397E-03 0,03596081 GO:0070201|regulation of establishment of protein localization, ! regulation of JUN kinase activity GO:0043506 58 28 1,000 6,494E-03 0,03642053 ! positive regulation of protein modification process GO:0031401 136 88 2,000 6,602E-03 0,03694154 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 6,811E-03 0,03802283 ! regulation of pH GO:0006885 43 29 1,000 6,955E-03 0,03873757 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 6,955E-03 0,0386481 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 6,955E-03 0,03855905 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 6,955E-03 0,03847041 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 6,955E-03 0,03838217 ! cell junction assembly GO:0034329 78 30 1,000 7,431E-03 0,04091444 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 7,431E-03 0,04082103 ! ensheathment of neurons GO:0007272 57 30 1,000 7,431E-03 0,04072804 GO:0008366|axon ensheathment, ! regulation of B cell activation GO:0050864 50 30 1,000 7,431E-03 0,04063548 ! response to heat GO:0009408 50 30 1,000 7,431E-03 0,04054333 ! regulation of membrane potential GO:0042391 164 93 2,000 7,687E-03 0,04184169 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 7,687E-03 0,04174724 ! female pregnancy GO:0007565 164 94 2,000 7,915E-03 0,04289266 ! regulation of T cell activation GO:0050863 158 94 2,000 7,915E-03 0,04279628 ! ovulation cycle process GO:0022602 49 31 1,000 7,921E-03 0,04273326 ! iron ion homeostasis GO:0055072 54 31 1,000 7,921E-03 0,04263766 ! erythrocyte differentiation GO:0030218 55 31 1,000 7,921E-03 0,04254249 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 7,921E-03 0,04244774 GO:0043433|negative regulation of transcription factor activity, ! forebrain development GO:0030900 188 95 2,000 8,148E-03 0,04356499 ! metanephros development GO:0001656 74 32 1,000 8,426E-03 0,04495031 ! response to mechanical stimulus GO:0009612 57 32 1,000 8,426E-03 0,04485086 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 8,426E-03 0,04475185 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 8,426E-03 0,04465328 ! ovulation cycle GO:0042698 51 32 1,000 8,426E-03 0,04455514 ! peripheral nervous system development GO:0007422 64 32 1,000 8,426E-03 0,04445743 ! hindbrain development GO:0030902 61 32 1,000 8,426E-03 0,04436015 ! positive regulation of catabolic process GO:0009896 64 32 1,000 8,426E-03 0,0442633 ! response to virus GO:0009615 160 98 2,000 8,87E-03 0,04649634 ! post-embryonic development GO:0009791 69 33 1,000 8,944E-03 0,04678252 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 8,944E-03 0,04668104 ! xenobiotic metabolic process GO:0006805 51 34 1,000 9,477E-03 0,04935247 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 9,477E-03 0,04924587 ! placenta development GO:0001890 53 34 1,000 9,477E-03 0,04913974 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 9,477E-03 0,04903406 ! regulation of muscle development GO:0048634 70 35 1,000 0,01002283 0,05174875 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01002283 0,05163794 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01002283 0,0515276 ! cell junction organization GO:0034330 86 36 1,000 0,01058266 0,05428974 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01058266 0,05417423 ! embryonic organ development GO:0048568 57 36 1,000 0,01058266 0,05405921 ! tissue remodeling GO:0048771 76 37 1,000 0,01115605 0,05686748 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01115605 0,05674725 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01115605 0,05662753 ! regulation of protein stability GO:0031647 73 37 1,000 0,01115605 0,05650831 ! pigment metabolic process GO:0042440 80 37 1,000 0,01115605 0,0563896 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,01174285 0,05923123 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01174285 0,05910732 ! learning GO:0007612 77 39 1,000 0,01234295 0,06199819 ! ear morphogenesis GO:0042471 60 39 1,000 0,01234295 0,06186903 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01234295 0,0617404 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01234295 0,06161231 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,01234295 0,06148475 ! negative regulation of binding GO:0051100 72 40 1,000 0,01295622 0,06440632 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01295622 0,06427352 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 1,000 0,01295622 0,06414127 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,01358253 0,06710386 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01358253 0,06696635 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01358253 0,0668294 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01487382 0,07303352 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01487382 0,07288477 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,01487382 0,07273663 ! male sex differentiation GO:0046661 76 44 1,000 0,01553856 0,0758332 ! biopolymer methylation GO:0043414 84 44 1,000 0,01553856 0,07567969 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01621585 0,07881886 ! cell growth GO:0016049 84 45 1,000 0,01621585 0,07865995 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01690559 0,08184074 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,01690559 0,0816764 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,01690559 0,08151272 ! response to calcium ion GO:0051592 81 47 1,000 0,01760766 0,08472804 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01760766 0,08455892 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01760766 0,08439048 ! methylation GO:0032259 90 47 1,000 0,01760766 0,0842227 ! protein homooligomerization GO:0051260 76 47 1,000 0,01760766 0,08405559 ! Notch signaling pathway GO:0007219 96 48 1,000 0,01832193 0,08729221 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,01832193 0,08711969 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01832193 0,08694786 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,0190483 0,09021693 ! regulation of action potential GO:0001508 95 49 1,000 0,0190483 0,09003969 ! response to temperature stimulus GO:0009266 76 49 1,000 0,0190483 0,08986314 ! endocrine system development GO:0035270 104 49 1,000 0,0190483 0,08968728 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,0190483 0,08951211 ! regulation of ossification GO:0030278 117 50 1,000 0,01978664 0,09280049 ! histone modification GO:0016570 91 50 1,000 0,01978664 0,09261995 ! viral infectious cycle GO:0019058 99 51 1,000 0,02053684 0,09594494 ! vesicle organization GO:0016050 107 51 1,000 0,02053684 0,095759 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,02053684 0,09557378 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,02129879 0,09892837 ! positive regulation of growth GO:0045927 90 52 1,000 0,02129879 0,09873775 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02129879 0,09854787 ! synapse organization GO:0050808 85 52 1,000 0,02129879 0,09835872 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02139838 0,09862934 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02139838 0,09844075 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02139838 0,09825289 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02139838 0,09806574 ! neuron fate determination GO:0048664 7 5 0,000 0,02139838 0,0978793 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02139838 0,09769357 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02139838 0,09750855 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02139838 0,09732422 ! polyol transport GO:0015791 12 5 0,000 0,02139838 0,09714059 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02139838 0,09695765 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02139838 0,0967754 ! response to superoxide GO:0000303 10 5 0,000 0,02139838 0,09659383 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02139838 0,09641295 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02139838 0,09623274 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02139838 0,0960532 ! female meiosis GO:0007143 7 5 0,000 0,02139838 0,09587433 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02139838 0,09569612 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02139838 0,09551858 ! cobalt ion transport GO:0006824 11 5 0,000 0,02139838 0,09534169 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02139838 0,09516546 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02139838 0,09498988 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02139838 0,09481494 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02139838 0,09464065 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02139838 0,094467 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02139838 0,09429398 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02139838 0,0941216 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02139838 0,09394984 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02139838 0,09377871 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02139838 0,09360821 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02139838 0,09343832 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02139838 0,09326905 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02139838 0,09310039 ! negative chemotaxis GO:0050919 14 5 0,000 0,02139838 0,09293233 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02139838 0,09276489 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02139838 0,09259805 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02139838 0,0924318 ! behavioral response to pain GO:0048266 9 5 0,000 0,02139838 0,09226615 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02139838 0,0921011 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02139838 0,09193663 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02139838 0,09177275 ! micturition GO:0060073 9 5 0,000 0,02139838 0,09160945 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02139838 0,09144674 ! copulation GO:0007620 9 5 0,000 0,02139838 0,0912846 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02139838 0,09112303 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02139838 0,09096204 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02139838 0,09080161 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02139838 0,09064175 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02139838 0,09048245 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02139838 0,09032371 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02139838 0,09016552 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02139838 0,09000789 ! grooming behavior GO:0007625 6 5 0,000 0,02139838 0,08985081 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02139838 0,08969427 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02139838 0,08953828 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02139838 0,08938284 ! response to protozoan GO:0001562 10 5 0,000 0,02139838 0,08922793 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02139838 0,08907355 ! lymph vessel development GO:0001945 10 5 0,000 0,02139838 0,08891971 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02139838 0,0887664 ! endochondral ossification GO:0001958 16 5 0,000 0,02139838 0,08861362 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02139838 0,08846136 ! parathyroid gland development GO:0060017 13 5 0,000 0,02139838 0,08830963 ! anagen GO:0042640 6 5 0,000 0,02139838 0,08815841 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02139838 0,08800772 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02139838 0,08785753 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02139838 0,08770786 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02139838 0,0875587 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02139838 0,08741004 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02139838 0,08726189 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02139838 0,08711424 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02139838 0,08696708 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02139838 0,08682043 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02139838 0,08667426 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02139838 0,08652859 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02139838 0,08638341 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02139838 0,08623872 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02139838 0,0860945 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02139838 0,08595077 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02139838 0,08580752 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02139838 0,08566475 ! histidine catabolic process GO:0006548 6 5 0,000 0,02139838 0,08552245 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02139838 0,08538062 ! microvillus organization GO:0032528 7 5 0,000 0,02139838 0,08523926 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02139838 0,08509837 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02139838 0,08495794 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02139838 0,08481798 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02139838 0,08467848 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02139838 0,08453943 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02139838 0,08440084 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02139838 0,08426271 ! polyol catabolic process GO:0046174 7 5 0,000 0,02139838 0,08412502 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02139838 0,08398779 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02139838 0,083851 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02139838 0,08371466 ! muscle cell migration GO:0014812 8 5 0,000 0,02139838 0,08357876 ! mitochondrial fission GO:0000266 8 5 0,000 0,02139838 0,0834433 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02139838 0,08330827 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02139838 0,08317369 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02139838 0,08303954 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02139838 0,08290582 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02139838 0,08277253 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02139838 0,08263967 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02139838 0,08250723 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02139838 0,08237522 ! response to food GO:0032094 6 5 0,000 0,02139838 0,08224363 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02139838 0,08211246 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02139838 0,08198171 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02139838 0,08185137 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02139838 0,08172145 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02139838 0,08159194 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02139838 0,08146284 ! forebrain neuron development GO:0021884 13 5 0,000 0,02139838 0,08133414 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02139838 0,08120586 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02139838 0,08107797 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02139838 0,08095049 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02139838 0,08082341 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02139838 0,08069673 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02139838 0,08057044 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02139838 0,08044455 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02139838 0,08031905 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02139838 0,08019395 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02139838 0,08006923 ! basic amino acid transport GO:0015802 11 5 0,000 0,02139838 0,0799449 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02139838 0,07982095 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02139838 0,07969739 ! depyrimidination GO:0045008 10 5 0,000 0,02139838 0,07957421 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02139838 0,07945141 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02139838 0,07932899 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02139838 0,07920694 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02139838 0,07908527 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02139838 0,07896398 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02139838 0,07884305 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02139838 0,0787225 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02139838 0,07860231 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02139838 0,07848249 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02139838 0,07836303 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02139838 0,07824394 ! response to arsenic GO:0046685 10 5 0,000 0,02139838 0,07812521 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02139838 0,07800684 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02139838 0,07788883 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02139838 0,07777117 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02139838 0,07765387 ! response to cadmium ion GO:0046686 7 5 0,000 0,02139838 0,07753692 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02139838 0,07742032 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02139838 0,07730407 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02139838 0,07718818 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02139838 0,07707262 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02139838 0,07695742 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02139838 0,07684256 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02139838 0,07672804 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02139838 0,07661386 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02139838 0,07650002 ! neural tube patterning GO:0021532 7 5 0,000 0,02139838 0,07638652 ! embryonic cleavage GO:0040016 6 5 0,000 0,02139838 0,07627335 ! peroxisome fission GO:0016559 5 5 0,000 0,02139838 0,07616052 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02139838 0,07604803 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02139838 0,07593586 ! metaphase plate congression GO:0051310 7 5 0,000 0,02139838 0,07582403 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02139838 0,07571252 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02139838 0,07560134 ! enteric nervous system development GO:0048484 8 5 0,000 0,02139838 0,07549049 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02139838 0,07537996 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02139838 0,07526976 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02139838 0,07515987 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02139838 0,07505031 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02139838 0,07494107 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02139838 0,07483214 ! plasminogen activation GO:0031639 5 5 0,000 0,02139838 0,07472353 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02139838 0,07461524 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02139838 0,07450726 ! metaphase GO:0051323 8 5 0,000 0,02139838 0,07439959 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02139838 0,07429223 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02139838 0,07418518 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02139838 0,07407844 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02139838 0,073972 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02139838 0,07386587 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02139838 0,07376005 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02139838 0,07365453 ! response to redox state GO:0051775 5 5 0,000 0,02139838 0,0735493 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02139838 0,07344438 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02139838 0,07333976 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02139838 0,07323544 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02139838 0,07313141 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02139838 0,07302768 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02139838 0,07292424 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02139838 0,07282109 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02139838 0,07271824 ! striatum development GO:0021756 9 5 0,000 0,02139838 0,07261567 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02139838 0,0725134 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02139838 0,07241141 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02139838 0,07230971 ! glial cell migration GO:0008347 11 5 0,000 0,02139838 0,07220829 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02139838 0,07210716 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02139838 0,07200631 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02139838 0,07190574 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02139838 0,07180546 ! neuroprotection GO:0043526 6 5 0,000 0,02139838 0,07170545 ! neural plate development GO:0001840 8 5 0,000 0,02139838 0,07160572 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02139838 0,07150627 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02139838 0,07140709 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02139838 0,07130819 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02139838 0,07120956 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02139838 0,07111121 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02139838 0,07101312 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02139838 0,07091531 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02139838 0,07081776 ! spindle assembly GO:0051225 6 5 0,000 0,02139838 0,07072049 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02139838 0,07062348 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02139838 0,07052673 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02139838 0,07043025 ! drug metabolic process GO:0017144 6 5 0,000 0,02139838 0,07033403 ! stem cell division GO:0017145 11 5 0,000 0,02139838 0,07023808 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02139838 0,07014239 ! organ regeneration GO:0031100 7 5 0,000 0,02139838 0,07004696 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02139838 0,06995178 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02139838 0,06985687 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02139838 0,06976221 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,02207237 0,07186216 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02285748 0,07431769 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,02285748 0,07421739 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02365399 0,07670012 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,02365399 0,07659689 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,02365399 0,07649394 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,02365399 0,07639126 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02446179 0,0788942 ! muscle fiber development GO:0048747 112 57 1,000 0,02528078 0,08142646 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02528078 0,0813176 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02562322 0,08230903 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02562322 0,08219929 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02562322 0,08208983 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02562322 0,08198067 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02562322 0,0818718 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02562322 0,08176322 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02562322 0,08165492 ! sleep GO:0030431 13 6 0,000 0,02562322 0,08154691 ! response to oxygen radical GO:0000305 11 6 0,000 0,02562322 0,08143919 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02562322 0,08133175 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02562322 0,08122459 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02562322 0,08111772 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02562322 0,08101112 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02562322 0,08090481 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02562322 0,08079877 ! forebrain regionalization GO:0021871 8 6 0,000 0,02562322 0,08069302 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02562322 0,08058754 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02562322 0,08048233 ! response to zinc ion GO:0010043 9 6 0,000 0,02562322 0,0803774 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02562322 0,08027274 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02562322 0,08016835 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02562322 0,08006424 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02562322 0,0799604 ! malate metabolic process GO:0006108 11 6 0,000 0,02562322 0,07985682 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02562322 0,07975351 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02562322 0,07965047 ! protein refolding GO:0042026 15 6 0,000 0,02562322 0,0795477 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02562322 0,07944519 ! opsonization GO:0008228 8 6 0,000 0,02562322 0,07934294 ! mating behavior GO:0007617 7 6 0,000 0,02562322 0,07924096 ! neuron remodeling GO:0016322 15 6 0,000 0,02562322 0,07913924 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02562322 0,07903778 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02562322 0,07893657 ! equilibrioception GO:0050957 14 6 0,000 0,02562322 0,07883563 ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02562322 0,07873495 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02562322 0,07863452 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02562322 0,07853435 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02562322 0,07843443 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02562322 0,07833477 ! toxin metabolic process GO:0009404 11 6 0,000 0,02562322 0,07823536 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02562322 0,0781362 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02562322 0,0780373 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02562322 0,07793864 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02562322 0,07784023 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02562322 0,07774207 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02562322 0,07764416 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02562322 0,0775465 ! thymic T cell selection GO:0045061 12 6 0,000 0,02562322 0,07744908 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02562322 0,0773519 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02562322 0,07725497 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02562322 0,07715828 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02562322 0,07706183 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02562322 0,07696562 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02562322 0,07686966 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02562322 0,07677393 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02562322 0,07667844 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02562322 0,07658319 ! hyperosmotic response GO:0006972 9 6 0,000 0,02562322 0,07648817 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02562322 0,07639339 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02562322 0,07629884 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02562322 0,07620453 ! urea metabolic process GO:0019627 7 6 0,000 0,02562322 0,07611045 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02562322 0,0760166 ! neutrophil activation GO:0042119 8 6 0,000 0,02562322 0,07592299 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02562322 0,0758296 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02562322 0,07573644 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02562322 0,07564351 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02562322 0,07555081 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02562322 0,07545834 ! nucleoside salvage GO:0043174 9 6 0,000 0,02562322 0,07536609 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02562322 0,07527407 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02562322 0,07518227 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02562322 0,0750907 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02562322 0,07499935 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02562322 0,07490822 ! carnitine transport GO:0015879 10 6 0,000 0,02562322 0,07481731 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02562322 0,07472662 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02562322 0,07463616 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02562322 0,07454591 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02562322 0,07445588 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02562322 0,07436606 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02562322 0,07427646 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02562322 0,07418708 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02562322 0,07409791 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02562322 0,07400896 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02562322 0,07392022 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02562322 0,07383169 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02562322 0,07374338 ! astrocyte development GO:0014002 15 6 0,000 0,02562322 0,07365527 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02562322 0,07356738 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02562322 0,0734797 ! interaction with symbiont GO:0051702 13 6 0,000 0,02562322 0,07339222 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02562322 0,07330495 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02562322 0,07321789 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02562322 0,07313104 ! response to copper ion GO:0046688 10 6 0,000 0,02562322 0,07304439 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02562322 0,07295795 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02562322 0,07287171 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02562322 0,07278567 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02562322 0,07269984 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02562322 0,07261421 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02562322 0,07252878 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02562322 0,07244355 ! hair follicle maturation GO:0048820 7 6 0,000 0,02562322 0,07235853 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02562322 0,0722737 ! Schwann cell development GO:0014044 15 6 0,000 0,02562322 0,07218907 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02562322 0,07210464 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02562322 0,0720204 ! subpallium development GO:0021544 10 6 0,000 0,02562322 0,07193636 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02562322 0,07185252 ! histone ubiquitination GO:0016574 8 6 0,000 0,02562322 0,07176888 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02562322 0,07168542 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02562322 0,07160217 ! tetracycline transport GO:0015904 8 6 0,000 0,02562322 0,0715191 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02562322 0,07143623 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02562322 0,07135355 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02562322 0,07127106 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02562322 0,07118876 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02562322 0,07110665 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02562322 0,07102473 ! receptor internalization GO:0031623 10 6 0,000 0,02562322 0,070943 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02562322 0,07086145 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02562322 0,0707801 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02562322 0,07069893 ! protein deubiquitination GO:0016579 14 6 0,000 0,02562322 0,07061794 ! protein destabilization GO:0031648 9 6 0,000 0,02562322 0,07053714 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02562322 0,07045653 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02562322 0,0703761 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02562322 0,07029585 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02562322 0,07021579 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02562322 0,07013591 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02562322 0,07005621 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02562322 0,06997669 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02562322 0,06989735 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02562322 0,06981819 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02562322 0,06973921 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02562322 0,06966041 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02562322 0,06958179 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02562322 0,06950334 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02562322 0,06942507 ! catecholamine transport GO:0051937 9 6 0,000 0,02562322 0,06934698 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02562322 0,06926906 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02562322 0,06919132 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02562322 0,06911375 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02562322 0,06903635 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02562322 0,06895913 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02562322 0,06888208 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02562322 0,06880521 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02562322 0,0687285 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02562322 0,06865197 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02562322 0,0685756 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02611085 0,069803 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02695188 0,07197139 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,02780377 0,07416393 ! kidney development GO:0001822 122 60 1,000 0,02780377 0,0740818 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,02866641 0,07629577 ! viral reproductive process GO:0022415 126 62 1,000 0,02953969 0,07853314 ! tRNA transcription GO:0009304 14 7 0,000 0,02982995 0,07921729 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02982995 0,07912995 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02982995 0,07904281 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02982995 0,07895585 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02982995 0,07886909 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02982995 0,07878251 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02982995 0,07869613 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02982995 0,07860993 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02982995 0,07852393 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02982995 0,07843811 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02982995 0,07835248 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02982995 0,07826703 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02982995 0,07818177 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02982995 0,0780967 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02982995 0,07801181 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02982995 0,07792711 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02982995 0,07784259 ! glycolipid transport GO:0046836 10 7 0,000 0,02982995 0,07775825 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02982995 0,0776741 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02982995 0,07759013 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02982995 0,07750634 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02982995 0,07742273 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02982995 0,0773393 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02982995 0,07725605 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02982995 0,07717298 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02982995 0,07709008 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02982995 0,07700737 ! pericardium development GO:0060039 14 7 0,000 0,02982995 0,07692483 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02982995 0,07684247 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02982995 0,07676029 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02982995 0,07667828 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02982995 0,07659644 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02982995 0,07651478 ! lipoprotein transport GO:0042953 14 7 0,000 0,02982995 0,0764333 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02982995 0,07635199 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02982995 0,07627085 ! rhythmic behavior GO:0007622 15 7 0,000 0,02982995 0,07618988 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02982995 0,07610909 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02982995 0,07602846 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02982995 0,07594801 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02982995 0,07586772 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02982995 0,07578761 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02982995 0,07570767 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02982995 0,07562789 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02982995 0,07554828 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02982995 0,07546884 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02982995 0,07538957 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02982995 0,07531046 ! spinal cord patterning GO:0021511 13 7 0,000 0,02982995 0,07523152 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02982995 0,07515274 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02982995 0,07507413 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02982995 0,07499568 ! adrenal gland development GO:0030325 17 7 0,000 0,02982995 0,0749174 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02982995 0,07483928 ! ovulation GO:0030728 9 7 0,000 0,02982995 0,07476132 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02982995 0,07468353 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02982995 0,07460589 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02982995 0,07452842 ! microtubule nucleation GO:0007020 20 7 0,000 0,02982995 0,07445111 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02982995 0,07437396 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02982995 0,07429696 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02982995 0,07422013 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02982995 0,07414346 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02982995 0,07406694 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02982995 0,07399059 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02982995 0,07391438 ! galactose metabolic process GO:0006012 13 7 0,000 0,02982995 0,07383834 ! vesicle fusion GO:0006906 17 7 0,000 0,02982995 0,07376245 ! response to dietary excess GO:0002021 8 7 0,000 0,02982995 0,07368672 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02982995 0,07361115 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02982995 0,07353573 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02982995 0,07346046 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02982995 0,07338535 ! purine salvage GO:0043101 10 7 0,000 0,02982995 0,07331039 ! nucleoside transport GO:0015858 8 7 0,000 0,02982995 0,07323558 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02982995 0,07316093 ! parturition GO:0007567 14 7 0,000 0,02982995 0,07308642 ! rRNA modification GO:0000154 14 7 0,000 0,02982995 0,07301207 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02982995 0,07293787 ! spindle checkpoint GO:0031577 15 7 0,000 0,02982995 0,07286383 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02982995 0,07278993 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02982995 0,07271618 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02982995 0,07264258 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02982995 0,07256913 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02982995 0,07249583 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02982995 0,07242267 ! fibrinolysis GO:0042730 10 7 0,000 0,02982995 0,07234967 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02982995 0,07227681 ! eating behavior GO:0042755 7 7 0,000 0,02982995 0,07220409 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02982995 0,07213153 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02982995 0,0720591 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02982995 0,07198683 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02982995 0,0719147 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02982995 0,07184271 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02982995 0,07177087 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02982995 0,07169917 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02982995 0,07162761 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02982995 0,0715562 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02982995 0,07148493 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02982995 0,0714138 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02982995 0,07134281 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02982995 0,07127196 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02982995 0,07120126 ! regulation of meiosis GO:0040020 12 7 0,000 0,02982995 0,07113069 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02982995 0,07106027 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02982995 0,07098998 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02982995 0,07091983 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02982995 0,07084982 ! transcription termination GO:0006353 13 7 0,000 0,02982995 0,07077995 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02982995 0,07071021 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02982995 0,07064062 ! anaphase GO:0051322 17 7 0,000 0,02982995 0,07057116 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02982995 0,07050183 ! axonal fasciculation GO:0007413 18 7 0,000 0,02982995 0,07043265 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02982995 0,0703636 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02982995 0,07029468 ! diuresis GO:0030146 12 7 0,000 0,02982995 0,0702259 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02982995 0,07015725 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02982995 0,07008874 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02982995 0,07002036 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02982995 0,06995211 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02982995 0,069884 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02982995 0,06981602 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02982995 0,06974817 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02982995 0,06968045 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02982995 0,06961287 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02982995 0,06954541 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02982995 0,06947809 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02982995 0,0694109 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,02982995 0,06934383 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02982995 0,0692769 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02982995 0,06921009 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02982995 0,06914342 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02982995 0,06907687 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02982995 0,06901045 ! adult feeding behavior GO:0008343 9 7 0,000 0,02982995 0,06894416 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02982995 0,06887799 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02982995 0,06881195 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02982995 0,06874604 ! muscle adaptation GO:0043500 14 7 0,000 0,02982995 0,06868026 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02982995 0,0686146 ! retina homeostasis GO:0001895 12 7 0,000 0,02982995 0,06854906 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02982995 0,06848365 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02982995 0,06841837 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02982995 0,06835321 ! protein prenylation GO:0018342 18 7 0,000 0,02982995 0,06828817 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02982995 0,06822326 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02982995 0,06815847 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02982995 0,0680938 ! regulation of mitosis GO:0007088 105 63 1,000 0,03042351 0,06938289 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,03042351 0,06931719 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,03131775 0,07128714 ! cell redox homeostasis GO:0045454 102 64 1,000 0,03131775 0,07121977 ! secondary metabolic process GO:0019748 116 66 1,000 0,03313712 0,07528603 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03401866 0,07721595 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03401866 0,07714317 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03401866 0,07707053 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03401866 0,07699803 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03401866 0,07692567 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03401866 0,07685343 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03401866 0,07678134 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03401866 0,07670938 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03401866 0,07663755 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03401866 0,07656586 ! meiotic prophase I GO:0007128 13 8 0,000 0,03401866 0,07649431 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03401866 0,07642288 ! oligopeptide transport GO:0006857 15 8 0,000 0,03401866 0,07635159 ! UTP metabolic process GO:0046051 8 8 0,000 0,03401866 0,07628044 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03401866 0,07620941 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03401866 0,07613852 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03401866 0,07606776 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03401866 0,07599713 ! succinate metabolic process GO:0006105 14 8 0,000 0,03401866 0,07592663 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03401866 0,07585626 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03401866 0,07578603 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03401866 0,07571592 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03401866 0,07564594 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03401866 0,07557609 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03401866 0,07550637 ! reflex GO:0060004 16 8 0,000 0,03401866 0,07543678 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03401866 0,07536732 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03401866 0,07529798 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03401866 0,07522878 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03401866 0,0751597 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03401866 0,07509074 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03401866 0,07502191 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03401866 0,07495321 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03401866 0,07488464 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03401866 0,07481619 ! histidine metabolic process GO:0006547 16 8 0,000 0,03401866 0,07474786 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03401866 0,07467966 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03401866 0,07461158 ! glycine catabolic process GO:0006546 13 8 0,000 0,03401866 0,07454363 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03401866 0,0744758 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03401866 0,0744081 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03401866 0,07434052 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03401866 0,07427306 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03401866 0,07420572 ! macrophage activation GO:0042116 12 8 0,000 0,03401866 0,0741385 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03401866 0,07407141 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03401866 0,07400444 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03401866 0,07393759 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03401866 0,07387086 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03401866 0,07380425 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03401866 0,07373775 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03401866 0,07367138 ! osteoblast development GO:0002076 16 8 0,000 0,03401866 0,07360513 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03401866 0,073539 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03401866 0,07347299 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03401866 0,07340709 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03401866 0,07334132 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03401866 0,07327566 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03401866 0,07321011 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03401866 0,07314469 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03401866 0,07307938 ! intermediate filament organization GO:0045109 12 8 0,000 0,03401866 0,07301419 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03401866 0,07294912 ! cellular extravasation GO:0045123 12 8 0,000 0,03401866 0,07288416 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03401866 0,07281931 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03401866 0,07275458 ! response to antibiotic GO:0046677 11 8 0,000 0,03401866 0,07268997 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03401866 0,07262547 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03401866 0,07256109 ! DNA topological change GO:0006265 12 8 0,000 0,03401866 0,07249682 ! response to tropane GO:0014073 15 8 0,000 0,03401866 0,07243266 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03401866 0,07236862 ! melanosome transport GO:0032402 13 8 0,000 0,03401866 0,07230469 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03401866 0,07224087 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03401866 0,07217717 ! mast cell activation GO:0045576 14 8 0,000 0,03401866 0,07211358 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03401866 0,07205009 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03401866 0,07198673 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03401866 0,07192347 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03401866 0,07186032 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03401866 0,07179729 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03401866 0,07173436 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03401866 0,07167155 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03401866 0,07160884 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03401866 0,07154625 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03401866 0,07148376 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03401866 0,07142139 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03401866 0,07135912 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03401866 0,07129696 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03401866 0,07123491 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03401866 0,07117296 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03401866 0,07111113 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03401866 0,0710494 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03401866 0,07098778 ! hormone catabolic process GO:0042447 17 8 0,000 0,03401866 0,07092626 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03401866 0,07086486 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03401866 0,07080355 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03401866 0,07074236 ! ATP catabolic process GO:0006200 11 8 0,000 0,03401866 0,07068127 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03401866 0,07062028 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03401866 0,0705594 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03401866 0,07049863 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03401866 0,07043796 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03401866 0,07037739 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03401866 0,07031693 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03401866 0,07025657 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03401866 0,07019632 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03401866 0,07013617 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03401866 0,07007612 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03401866 0,07001617 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03401866 0,06995633 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03401866 0,06989659 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03401866 0,06983695 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03401866 0,06977742 ! adaptive immune response GO:0002250 119 67 1,000 0,03406203 0,06980685 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 0,03499695 0,07166185 ! regulation of lipase activity GO:0060191 130 68 1,000 0,03499695 0,07160091 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,03499695 0,07154007 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,03499695 0,07147934 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,03594179 0,07334686 ! humoral immune response GO:0006959 109 71 1,000 0,03786079 0,07719752 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,03786079 0,07713215 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03818943 0,07773585 ! axon extension GO:0048675 15 9 0,000 0,03818943 0,07767013 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03818943 0,07760453 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03818943 0,07753905 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03818943 0,07747367 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03818943 0,0774084 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03818943 0,07734324 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03818943 0,07727819 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03818943 0,07721325 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03818943 0,07714842 ! phosphate transport GO:0006817 19 9 0,000 0,03818943 0,0770837 ! reproductive behavior GO:0019098 19 9 0,000 0,03818943 0,07701909 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03818943 0,07695458 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03818943 0,07689018 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03818943 0,07682589 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03818943 0,07676171 ! GTP metabolic process GO:0046039 9 9 0,000 0,03818943 0,07669764 ! RNA methylation GO:0001510 15 9 0,000 0,03818943 0,07663367 ! artery development GO:0060840 24 9 0,000 0,03818943 0,07656981 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03818943 0,07650605 ! regulation of glycolysis GO:0006110 21 9 0,000 0,03818943 0,0764424 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03818943 0,07637886 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03818943 0,07631542 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03818943 0,07625209 ! chemosensory behavior GO:0007635 20 9 0,000 0,03818943 0,07618886 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03818943 0,07612574 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03818943 0,07606272 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03818943 0,07599981 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03818943 0,075937 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03818943 0,07587429 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03818943 0,07581169 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03818943 0,07574919 ! protein targeting to ER GO:0045047 22 9 0,000 0,03818943 0,0756868 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03818943 0,0756245 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03818943 0,07556231 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,03818943 0,07550022 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03818943 0,07543823 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03818943 0,07537635 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03818943 0,07531457 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03818943 0,07525288 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03818943 0,0751913 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03818943 0,07512982 ! mannose metabolic process GO:0006013 13 9 0,000 0,03818943 0,07506844 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03818943 0,07500716 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03818943 0,07494598 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03818943 0,0748849 ! receptor clustering GO:0043113 18 9 0,000 0,03818943 0,07482392 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03818943 0,07476303 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03818943 0,07470225 ! ruffle organization GO:0031529 15 9 0,000 0,03818943 0,07464157 ! retinol metabolic process GO:0042572 18 9 0,000 0,03818943 0,07458098 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03818943 0,07452049 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03818943 0,0744601 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03818943 0,07439981 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03818943 0,07433962 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,03818943 0,07427952 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03818943 0,07421952 ! segment specification GO:0007379 13 9 0,000 0,03818943 0,07415962 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03818943 0,07409981 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03818943 0,0740401 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03818943 0,07398049 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03818943 0,07392097 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03818943 0,07386155 ! erythrocyte development GO:0048821 15 9 0,000 0,03818943 0,07380222 ! gas homeostasis GO:0033483 16 9 0,000 0,03818943 0,07374299 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03818943 0,07368386 ! renal water homeostasis GO:0003091 14 9 0,000 0,03818943 0,07362482 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03818943 0,07356587 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03818943 0,07350702 ! icosanoid secretion GO:0032309 15 9 0,000 0,03818943 0,07344826 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03818943 0,07338959 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03818943 0,07333102 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03818943 0,07327254 ! regulation of cell division GO:0051302 15 9 0,000 0,03818943 0,07321416 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03818943 0,07315587 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03818943 0,07309767 ! sterol catabolic process GO:0016127 11 9 0,000 0,03818943 0,07303956 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03818943 0,07298155 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03818943 0,07292363 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03818943 0,0728658 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03818943 0,07280806 GO:0000084|S phase of mitotic cell cycle, ! musculoskeletal movement GO:0050881 14 9 0,000 0,03818943 0,07275041 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03818943 0,07269286 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03818943 0,07263539 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03818943 0,07257802 ! purine base metabolic process GO:0006144 21 9 0,000 0,03818943 0,07252073 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03818943 0,07246354 ! pigment granule transport GO:0051904 17 9 0,000 0,03818943 0,07240644 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03818943 0,07234942 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03818943 0,0722925 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03818943 0,07223567 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03818943 0,07217892 ! mitochondrion localization GO:0051646 15 9 0,000 0,03818943 0,07212227 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,03883476 0,07328348 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,03883476 0,07322605 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,03883476 0,0731687 ! learning or memory GO:0007611 147 73 1,000 0,03981824 0,07496297 ! regulation of blood pressure GO:0008217 125 73 1,000 0,03981824 0,07490436 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,03981824 0,07484584 ! axon guidance GO:0007411 139 73 1,000 0,03981824 0,07478742 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,04081113 0,07659249 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,04181333 0,07841221 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,04181333 0,07835114 ! rhythmic process GO:0048511 128 75 1,000 0,04181333 0,07829017 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04234233 0,079219 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04234233 0,07915745 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04234233 0,07909599 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04234233 0,07903463 ! synapsis GO:0007129 13 10 0,000 0,04234233 0,07897336 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04234233 0,07891219 ! N-glycan processing GO:0006491 20 10 0,000 0,04234233 0,07885111 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04234233 0,07879013 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04234233 0,07872924 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04234233 0,07866844 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04234233 0,07860774 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04234233 0,07854714 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04234233 0,07848662 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04234233 0,0784262 ! androgen metabolic process GO:0008209 17 10 0,000 0,04234233 0,07836587 ! phospholipid efflux GO:0033700 16 10 0,000 0,04234233 0,07830564 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04234233 0,0782455 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04234233 0,07818545 ! pathogenesis GO:0009405 13 10 0,000 0,04234233 0,07812549 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04234233 0,07806562 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04234233 0,07800585 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04234233 0,07794616 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04234233 0,07788657 ! endoderm development GO:0007492 16 10 0,000 0,04234233 0,07782707 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04234233 0,07776766 ! arginine catabolic process GO:0006527 13 10 0,000 0,04234233 0,07770834 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04234233 0,07764911 ! proline metabolic process GO:0006560 13 10 0,000 0,04234233 0,07758997 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04234233 0,07753093 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04234233 0,07747197 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04234233 0,0774131 ! V(D)J recombination GO:0033151 28 10 0,000 0,04234233 0,07735432 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04234233 0,07729563 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04234233 0,07723702 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04234233 0,07717851 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04234233 0,07712009 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04234233 0,07706175 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04234233 0,0770035 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04234233 0,07694534 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04234233 0,07688727 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04234233 0,07682929 ! macroautophagy GO:0016236 17 10 0,000 0,04234233 0,07677139 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04234233 0,07671358 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04234233 0,07665586 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04234233 0,07659822 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04234233 0,07654067 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04234233 0,07648321 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04234233 0,07642583 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04234233 0,07636854 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04234233 0,07631134 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04234233 0,07625422 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04234233 0,07619718 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04234233 0,07614024 ! response to dsRNA GO:0043331 20 10 0,000 0,04234233 0,07608337 ! DNA ligation GO:0006266 19 10 0,000 0,04234233 0,07602659 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04234233 0,0759699 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04234233 0,07591329 ! melanosome localization GO:0032400 16 10 0,000 0,04234233 0,07585677 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04234233 0,07580032 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04234233 0,07574397 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04234233 0,07568769 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04234233 0,0756315 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04234233 0,0755754 ! mRNA cleavage GO:0006379 17 10 0,000 0,04234233 0,07551937 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04234233 0,07546343 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04234233 0,07540758 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04234233 0,0753518 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04234233 0,07529611 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04234233 0,0752405 ! salivary gland development GO:0007431 27 10 0,000 0,04234233 0,07518497 ! prophase GO:0051324 15 10 0,000 0,04234233 0,07512952 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04234233 0,07507416 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04234233 0,07501888 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04234233 0,07496368 ! midbrain development GO:0030901 13 10 0,000 0,04234233 0,07490856 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04234233 0,07485352 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04234233 0,07479856 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04234233 0,07474368 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04234233 0,07468888 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04234233 0,07463417 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04234233 0,07457953 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04234233 0,07452497 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04234233 0,07447049 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04234233 0,0744161 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04234233 0,07436178 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04234233 0,07430754 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04234233 0,07425338 ! activation of innate immune response GO:0002218 12 10 0,000 0,04234233 0,0741993 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04234233 0,0741453 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04234233 0,07409137 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04234233 0,07403753 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04234233 0,07398376 ! localization within membrane GO:0051668 20 10 0,000 0,04234233 0,07393007 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,04282474 0,07471815 ! regulation of catabolic process GO:0009894 161 76 1,000 0,04282474 0,07466401 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,04384528 0,07638794 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,04487484 0,07812508 ! sensory perception of chemical stimulus GO:0007606 109 79 1,000 0,04591332 0,07987524 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,04591332 0,07981752 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,04591332 0,07975989 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04647743 0,08068159 ! respiratory burst GO:0045730 17 11 0,000 0,04647743 0,08062342 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04647743 0,08056534 ! neuron fate specification GO:0048665 17 11 0,000 0,04647743 0,08050734 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04647743 0,08044942 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04647743 0,08039158 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04647743 0,08033383 ! thyroid gland development GO:0030878 26 11 0,000 0,04647743 0,08027616 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,04647743 0,08021857 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04647743 0,08016107 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04647743 0,08010365 ! response to pain GO:0048265 24 11 0,000 0,04647743 0,08004631 ! T cell proliferation GO:0042098 26 11 0,000 0,04647743 0,07998905 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04647743 0,07993187 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,04647743 0,07987478 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04647743 0,07981777 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04647743 0,07976083 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04647743 0,07970398 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04647743 0,07964721 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04647743 0,07959053 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04647743 0,07953392 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04647743 0,07947739 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04647743 0,07942094 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04647743 0,07936458 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,04647743 0,07930829 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04647743 0,07925208 ! UV protection GO:0009650 19 11 0,000 0,04647743 0,07919596 ! adult heart development GO:0007512 14 11 0,000 0,04647743 0,07913991 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04647743 0,07908394 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04647743 0,07902805 ! temperature homeostasis GO:0001659 17 11 0,000 0,04647743 0,07897224 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04647743 0,07891651 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04647743 0,07886085 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04647743 0,07880528 ! regulation of organ growth GO:0046620 13 11 0,000 0,04647743 0,07874978 ! pigment granule localization GO:0051875 20 11 0,000 0,04647743 0,07869436 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04647743 0,07863902 ! vasoconstriction GO:0042310 18 11 0,000 0,04647743 0,07858376 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04647743 0,07852857 ! embryonic axis specification GO:0000578 18 11 0,000 0,04647743 0,07847347 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04647743 0,07841844 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04647743 0,07836348 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04647743 0,07830861 ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04647743 0,07825381 ! zymogen activation GO:0031638 15 11 0,000 0,04647743 0,07819908 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04647743 0,07814444 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04647743 0,07808987 ! nucleosome positioning GO:0016584 15 11 0,000 0,04647743 0,07803537 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04647743 0,07798096 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04647743 0,07792661 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04647743 0,07787235 ! acid secretion GO:0046717 18 11 0,000 0,04647743 0,07781816 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04647743 0,07776404 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04647743 0,07771 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04647743 0,07765603 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04647743 0,07760214 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04647743 0,07754833 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,04647743 0,07749459 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04647743 0,07744092 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04647743 0,07738733 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04647743 0,07733381 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04647743 0,07728037 ! embryonic gut development GO:0048566 15 11 0,000 0,04647743 0,077227 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04647743 0,0771737 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04647743 0,07712048 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04647743 0,07706733 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04647743 0,07701425 ! defense response to fungus GO:0050832 13 11 0,000 0,04647743 0,07696125 ! developmental induction GO:0031128 19 11 0,000 0,04647743 0,07690831 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04647743 0,07685546 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04647743 0,07680267 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04647743 0,07674996 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04647743 0,07669732 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04647743 0,07664475 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04647743 0,07659225 ! muscle cell differentiation GO:0042692 159 80 1,000 0,04696064 0,07733559 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,04801669 0,07902063 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 1,000 0,04801669 0,07896662 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,04801669 0,07891268 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,04801669 0,07885881 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05059481 0,08303623 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05059481 0,08297963 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05059481 0,0829231 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05059481 0,08286665 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05059481 0,08281028 ! virus-host interaction GO:0019048 29 12 0,000 0,05059481 0,08275399 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05059481 0,08269777 ! cartilage condensation GO:0001502 20 12 0,000 0,05059481 0,08264162 ! mating GO:0007618 17 12 0,000 0,05059481 0,08258556 ! protein complex disassembly GO:0043241 27 12 0,000 0,05059481 0,08252957 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05059481 0,08247365 ! hippocampus development GO:0021766 26 12 0,000 0,05059481 0,08241782 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,05059481 0,08236205 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05059481 0,08230636 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05059481 0,08225075 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05059481 0,08219521 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05059481 0,08213975 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05059481 0,08208436 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05059481 0,08202905 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05059481 0,08197381 ! drug transport GO:0015893 16 12 0,000 0,05059481 0,08191865 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05059481 0,08186356 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05059481 0,08180854 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05059481 0,0817536 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05059481 0,08169873 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05059481 0,08164394 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05059481 0,08158922 ! forebrain cell migration GO:0021885 21 12 0,000 0,05059481 0,08153457 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05059481 0,08148 ! monoamine transport GO:0015844 18 12 0,000 0,05059481 0,08142549 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05059481 0,08137106 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05059481 0,08131671 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05059481 0,08126243 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05059481 0,08120821 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05059481 0,08115408 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05059481 0,08110001 ! protein homotetramerization GO:0051289 21 12 0,000 0,05059481 0,08104601 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05059481 0,08099209 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05059481 0,08093824 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05059481 0,08088446 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05059481 0,08083075 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05059481 0,08077712 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05059481 0,08072355 ! cranial nerve development GO:0021545 20 12 0,000 0,05059481 0,08067006 ! fucose catabolic process GO:0019317 22 12 0,000 0,05059481 0,08061663 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05059481 0,08056328 ! histone acetylation GO:0016573 26 12 0,000 0,05059481 0,08051 ! histone methylation GO:0016571 26 12 0,000 0,05059481 0,08045678 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05059481 0,08040364 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05059481 0,08035057 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05059481 0,08029757 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05059481 0,08024464 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05059481 0,08019177 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05059481 0,08013898 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05059481 0,08008626 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05059481 0,0800336 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05059481 0,07998102 ! response to cold GO:0009409 17 12 0,000 0,05059481 0,07992851 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05059481 0,07987606 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05059481 0,07982368 ! regulation of ligase activity GO:0051340 142 84 1,000 0,05123635 0,08078286 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,05232642 0,08244752 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05469455 0,08612244 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05469455 0,08606611 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05469455 0,08600986 ! peroxisomal transport GO:0043574 24 13 0,000 0,05469455 0,08595368 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05469455 0,08589758 ! lipid localization GO:0010876 28 13 0,000 0,05469455 0,08584154 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05469455 0,08578559 ! organelle fusion GO:0048284 32 13 0,000 0,05469455 0,0857297 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05469455 0,08567389 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05469455 0,08561814 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05469455 0,08556248 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05469455 0,08550688 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05469455 0,08545136 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05469455 0,0853959 ! methionine metabolic process GO:0006555 27 13 0,000 0,05469455 0,08534052 ! plasma membrane organization GO:0007009 24 13 0,000 0,05469455 0,08528522 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05469455 0,08522998 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05469455 0,08517481 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05469455 0,08511972 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05469455 0,0850647 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05469455 0,08500975 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05469455 0,08495487 ! exocrine system development GO:0035272 32 13 0,000 0,05469455 0,08490006 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05469455 0,08484532 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05469455 0,08479065 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05469455 0,08473605 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05469455 0,08468152 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05469455 0,08462707 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05469455 0,08457268 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05469455 0,08451836 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05469455 0,08446411 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05469455 0,08440993 ! ribosome assembly GO:0042255 17 13 0,000 0,05469455 0,08435583 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,05469455 0,08430179 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05469455 0,08424782 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05469455 0,08419391 ! chromatin silencing GO:0006342 26 13 0,000 0,05469455 0,08414008 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05469455 0,08408632 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05469455 0,08403262 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05469455 0,083979 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05469455 0,08392544 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05469455 0,08387195 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05469455 0,08381853 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05469455 0,08376517 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05469455 0,08371189 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05469455 0,08365867 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05469455 0,08360552 ! insulin secretion GO:0030073 23 13 0,000 0,05469455 0,08355244 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05469455 0,08349942 ! acrosome reaction GO:0007340 18 13 0,000 0,05469455 0,08344647 ! regulation of DNA binding GO:0051101 155 88 1,000 0,05564594 0,08484418 ! cellular defense response GO:0006968 114 89 1,000 0,05676857 0,08650107 ! ossification GO:0001503 188 90 1,000 0,05789913 0,08816791 ! rRNA transcription GO:0009303 25 14 0,000 0,05877672 0,08944769 ! lactation GO:0007595 26 14 0,000 0,05877672 0,08939115 ! reproductive cellular process GO:0048610 20 14 0,000 0,05877672 0,08933468 ! tRNA modification GO:0006400 20 14 0,000 0,05877672 0,08927828 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05877672 0,08922195 ! water transport GO:0006833 21 14 0,000 0,05877672 0,0891657 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05877672 0,08910951 ! non-recombinational repair GO:0000726 25 14 0,000 0,05877672 0,0890534 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05877672 0,08899735 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05877672 0,08894138 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05877672 0,08888548 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05877672 0,08882964 ! palate development GO:0060021 31 14 0,000 0,05877672 0,08877388 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05877672 0,08871819 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05877672 0,08866257 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05877672 0,08860701 ! arginine metabolic process GO:0006525 17 14 0,000 0,05877672 0,08855153 ! regulation of heart rate GO:0002027 24 14 0,000 0,05877672 0,08849612 ! organic alcohol transport GO:0015850 29 14 0,000 0,05877672 0,08844077 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05877672 0,0883855 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05877672 0,08833029 ! embryo implantation GO:0007566 30 14 0,000 0,05877672 0,08827515 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05877672 0,08822008 ! L-amino acid transport GO:0015807 30 14 0,000 0,05877672 0,08816508 ! stem cell development GO:0048864 43 14 0,000 0,05877672 0,08811015 GO:0019827|stem cell maintenance, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05877672 0,08805529 ! cerebellum development GO:0021549 21 14 0,000 0,05877672 0,08800049 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05877672 0,08794577 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05877672 0,08789111 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05877672 0,08783652 ! cofactor transport GO:0051181 26 14 0,000 0,05877672 0,08778199 ! NADP metabolic process GO:0006739 24 14 0,000 0,05877672 0,08772754 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05877672 0,08767315 ! intestinal absorption GO:0050892 25 14 0,000 0,05877672 0,08761883 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05877672 0,08756458 ! oxygen transport GO:0015671 21 14 0,000 0,05877672 0,08751039 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05877672 0,08745627 ! male genitalia development GO:0030539 24 14 0,000 0,05877672 0,08740222 ! regulation of axon extension GO:0030516 37 14 0,000 0,05877672 0,08734824 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05877672 0,08729432 ! bone development GO:0060348 189 91 1,000 0,05903751 0,08762754 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,06133742 0,09098509 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,06133742 0,09092903 ! transcription initiation GO:0006352 153 94 1,000 0,06249876 0,09259361 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0628414 0,09304395 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0628414 0,09298672 ! superoxide anion generation GO:0042554 20 15 0,000 0,0628414 0,09292957 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0628414 0,09287249 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0628414 0,09281548 ! copper ion transport GO:0006825 20 15 0,000 0,0628414 0,09275853 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0628414 0,09270166 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0628414 0,09264486 ! sulfate transport GO:0008272 23 15 0,000 0,0628414 0,09258813 ! response to cAMP GO:0051591 22 15 0,000 0,0628414 0,09253146 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0628414 0,09247487 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0628414 0,09241834 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0628414 0,09236189 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0628414 0,0923055 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0628414 0,09224918 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0628414 0,09219293 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0628414 0,09213675 ! vesicle coating GO:0006901 33 15 0,000 0,0628414 0,09208064 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0628414 0,0920246 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0628414 0,09196862 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0628414 0,09191271 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0628414 0,09185687 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0628414 0,0918011 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0628414 0,0917454 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0628414 0,09168976 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0628414 0,09163419 ! histone deacetylation GO:0016575 20 15 0,000 0,0628414 0,09157869 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0628414 0,09152325 ! tissue regeneration GO:0042246 26 15 0,000 0,0628414 0,09146788 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0628414 0,09141258 ! water homeostasis GO:0030104 27 15 0,000 0,0628414 0,09135735 ! muscle maintenance GO:0046716 26 15 0,000 0,0628414 0,09130218 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0628414 0,09124708 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0628414 0,09119205 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0628414 0,09113708 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0628414 0,09108218 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0628414 0,09102734 ! cell killing GO:0001906 29 15 0,000 0,0628414 0,09097257 ! detection of bacterium GO:0016045 18 15 0,000 0,0628414 0,09091787 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0628414 0,09086323 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0628414 0,09080866 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0628414 0,09075415 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0628414 0,09069971 ! peptide hormone processing GO:0016486 23 15 0,000 0,0628414 0,09064533 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,0636676 0,09178205 ! detection of stimulus GO:0051606 151 96 1,000 0,06484383 0,09342171 ! protein ubiquitination GO:0016567 217 97 1,000 0,06602737 0,09506993 ! hormone metabolic process GO:0042445 157 97 1,000 0,06602737 0,09501307 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06688866 0,09619493 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06688866 0,09613747 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06688866 0,09608007 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06688866 0,09602274 ! bone remodeling GO:0046849 27 16 0,000 0,06688866 0,09596549 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06688866 0,09590829 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06688866 0,09585117 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06688866 0,09579412 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06688866 0,09573713 ! startle response GO:0001964 28 16 0,000 0,06688866 0,09568021 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06688866 0,09562336 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06688866 0,09556658 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06688866 0,09550986 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06688866 0,09545321 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06688866 0,09539663 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06688866 0,09534012 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06688866 0,09528367 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06688866 0,09522729 ! response to osmotic stress GO:0006970 25 16 0,000 0,06688866 0,09517097 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06688866 0,09511473 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06688866 0,09505855 ! fructose metabolic process GO:0006000 25 16 0,000 0,06688866 0,09500243 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06688866 0,09494638 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06688866 0,0948904 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06688866 0,09483448 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06688866 0,09477863 ! axon cargo transport GO:0008088 43 16 0,000 0,06688866 0,09472285 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06688866 0,09466713 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06688866 0,09461147 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06688866 0,09455589 ! DNA replication initiation GO:0006270 27 16 0,000 0,06688866 0,09450036 ! neuron recognition GO:0008038 35 16 0,000 0,06688866 0,09444491 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06688866 0,09438951 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06688866 0,09433418 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06688866 0,09427892 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06688866 0,09422372 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06688866 0,09416859 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06688866 0,09411352 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06688866 0,09405851 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06688866 0,09400357 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06688866 0,0939487 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,06841606 0,09603795 GO:0060538|skeletal muscle organ development, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07091858 0,09949277 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07091858 0,09943479 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07091858 0,09937687 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07091858 0,09931903 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07091858 0,09926125 ! signal complex assembly GO:0007172 41 17 0,000 0,07091858 0,09920354 ! inositol metabolic process GO:0006020 28 17 0,000 0,07091858 0,0991459 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07091858 0,09908832 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07091858 0,09903081 ! glial cell development GO:0021782 27 17 0,000 0,07091858 0,09897337 ! limbic system development GO:0021761 36 17 0,000 0,07091858 0,098916 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07091858 0,09885869 ! adult walking behavior GO:0007628 33 17 0,000 0,07091858 0,09880144 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07091858 0,09874427 ! heart looping GO:0001947 30 17 0,000 0,07091858 0,09868716 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07091858 0,09863011 ! myoblast differentiation GO:0045445 45 17 0,000 0,07091858 0,09857313 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07091858 0,09851622 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07091858 0,09845937 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07091858 0,09840259 ! glycine metabolic process GO:0006544 28 17 0,000 0,07091858 0,09834588 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,07091858 0,09828922 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07091858 0,09823264 ! NAD metabolic process GO:0019674 29 17 0,000 0,07091858 0,09817612 ! membrane budding GO:0006900 37 17 0,000 0,07091858 0,09811966 ! DNA integration GO:0015074 29 17 0,000 0,07091858 0,09806327 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,07091858 0,09800695 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07091858 0,09795069 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07091858 0,09789449 ! genitalia development GO:0048806 30 17 0,000 0,07091858 0,09783836 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07091858 0,09778229 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07091858 0,09772629 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07091858 0,09767035 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07091858 0,09761447 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07091858 0,09755866 ! steroid catabolic process GO:0006706 31 17 0,000 0,07091858 0,09750291 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07091858 0,09744723 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07091858 0,09739161 ! gas transport GO:0015669 25 17 0,000 0,07091858 0,09733605 ! organic cation transport GO:0015695 31 17 0,000 0,07091858 0,09728056 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07091858 0,09722512 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07091858 0,09716976 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07091858 0,09711445 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07493122 0,10255092 ! neuron maturation GO:0042551 42 18 0,000 0,07493122 0,10249262 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07493122 0,10243438 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,07493122 0,10237622 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07493122 0,10231811 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07493122 0,10226008 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07493122 0,10220211 ! memory GO:0007613 31 18 0,000 0,07493122 0,1021442 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07493122 0,10208636 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07493122 0,10202859 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07493122 0,10197088 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07493122 0,10191324 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07493122 0,10185566 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07493122 0,10179815 ! response to retinoic acid GO:0032526 26 18 0,000 0,07493122 0,1017407 ! response to fungus GO:0009620 21 18 0,000 0,07493122 0,10168331 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07493122 0,101626 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07493122 0,10156874 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07493122 0,10151155 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07493122 0,10145443 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07493122 0,10139737 ! vitamin transport GO:0051180 27 18 0,000 0,07493122 0,10134037 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07493122 0,10128344 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07493122 0,10122657 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,07493122 0,10116976 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,07493122 0,10111302 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07493122 0,10105634 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07493122 0,10099973 ! nerve development GO:0021675 28 18 0,000 0,07493122 0,10094318 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07493122 0,10088669 ! protein secretion GO:0009306 39 19 0,000 0,07892667 0,10620669 ! positive regulation of translation GO:0045727 30 19 0,000 0,07892667 0,10614732 ! negative regulation of defense response GO:0031348 25 19 0,000 0,07892667 0,10608802 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,07892667 0,10602879 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,07892667 0,10596962 ! skin development GO:0043588 36 19 0,000 0,07892667 0,10591052 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07892667 0,10585148 ! lipid phosphorylation GO:0046834 35 19 0,000 0,07892667 0,10579251 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07892667 0,10573361 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,07892667 0,10567477 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07892667 0,105616 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07892667 0,10555729 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07892667 0,10549864 ! cerebral cortex development GO:0021987 36 19 0,000 0,07892667 0,10544007 ! pigmentation during development GO:0048066 41 19 0,000 0,07892667 0,10538155 ! response to vitamin A GO:0033189 27 19 0,000 0,07892667 0,10532311 ! heme metabolic process GO:0042168 36 19 0,000 0,07892667 0,10526472 ! actin filament bundle formation GO:0051017 42 19 0,000 0,07892667 0,1052064 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,07892667 0,10514815 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07892667 0,10508996 ! peptide cross-linking GO:0018149 37 19 0,000 0,07892667 0,10503184 ! protein export from nucleus GO:0006611 36 19 0,000 0,07892667 0,10497378 ! heart process GO:0003015 30 19 0,000 0,07892667 0,10491578 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,07892667 0,10485785 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,07892667 0,10479998 ! visual learning GO:0008542 36 19 0,000 0,07892667 0,10474217 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07892667 0,10468443 ! cell-cell junction organization GO:0045216 35 19 0,000 0,07892667 0,10462675 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07892667 0,10456914 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07892667 0,10451159 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,07892667 0,1044541 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07892667 0,10439668 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,07892667 0,10433932 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,07892667 0,10428202 ! cilium assembly GO:0042384 37 19 0,000 0,07892667 0,10422479 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07892667 0,10416761 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08290499 0,10935822 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08290499 0,1092983 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08290499 0,10923845 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08290499 0,10917865 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08290499 0,10911893 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,08290499 0,10905927 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,08290499 0,10899967 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08290499 0,10894014 ! response to vitamin GO:0033273 31 20 0,000 0,08290499 0,10888068 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08290499 0,10882128 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08290499 0,10876194 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08290499 0,10870267 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08290499 0,10864347 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08290499 0,10858432 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,08290499 0,10852525 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08290499 0,10846623 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08290499 0,10840728 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,08290499 0,1083484 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08290499 0,10828958 ! body fluid secretion GO:0007589 31 20 0,000 0,08290499 0,10823082 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08290499 0,10817213 ! peptide secretion GO:0002790 35 20 0,000 0,08290499 0,1081135 ! stem cell differentiation GO:0048863 53 20 0,000 0,08290499 0,10805493 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08290499 0,10799643 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08290499 0,10793799 ! sensory perception of pain GO:0019233 30 20 0,000 0,08290499 0,10787961 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08290499 0,1078213 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08290499 0,10776305 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08290499 0,10770486 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08290499 0,10764674 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08290499 0,10758867 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08290499 0,10753068 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08290499 0,10747274 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08290499 0,10741486 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08290499 0,10735705 ! regulation of glucose import GO:0046324 29 20 0,000 0,08290499 0,1072993 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08290499 0,10724161 ! actin filament-based movement GO:0030048 43 20 0,000 0,08290499 0,10718399 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,08290499 0,10712642 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08290499 0,10706892 ! negative regulation of translation GO:0017148 29 20 0,000 0,08290499 0,10701148 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08290499 0,1069541 ! regulation of cell killing GO:0031341 42 21 0,000 0,08686626 0,1120044 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08686626 0,11194441 ! hormone secretion GO:0046879 38 21 0,000 0,08686626 0,11188449 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08686626 0,11182462 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08686626 0,11176482 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08686626 0,11170509 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08686626 0,11164542 ! axis specification GO:0009798 38 21 0,000 0,08686626 0,11158581 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08686626 0,11152626 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08686626 0,11146678 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08686626 0,11140737 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08686626 0,11134801 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08686626 0,11128872 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08686626 0,11122949 ! cytolysis GO:0019835 24 21 0,000 0,08686626 0,11117033 ! vasodilation GO:0042311 39 21 0,000 0,08686626 0,11111123 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08686626 0,11105219 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08686626 0,11099321 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08686626 0,1109343 ! collagen fibril organization GO:0030199 59 21 0,000 0,08686626 0,11087545 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08686626 0,11081666 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08686626 0,11075793 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08686626 0,11069927 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08686626 0,11064067 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08686626 0,11058213 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08686626 0,11052365 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08686626 0,11046523 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08686626 0,11040688 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09081055 0,11535913 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09081055 0,11529825 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09081055 0,11523744 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09081055 0,11517669 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09081055 0,11511601 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09081055 0,11505539 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09081055 0,11499483 ! keratinization GO:0031424 28 22 0,000 0,09081055 0,11493434 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,09081055 0,11487391 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09081055 0,11481355 ! vacuolar transport GO:0007034 36 22 0,000 0,09081055 0,11475325 ! lysosome organization GO:0007040 41 22 0,000 0,09081055 0,11469301 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09081055 0,11463283 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09081055 0,11457272 ! fucose metabolic process GO:0006004 39 22 0,000 0,09081055 0,11451267 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09081055 0,11445269 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09081055 0,11439277 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09081055 0,11433291 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,09081055 0,11427311 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09081055 0,11421337 ! sarcomere organization GO:0045214 30 22 0,000 0,09081055 0,1141537 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,09081055 0,11409409 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09081055 0,11403454 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09081055 0,11397506 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09081055 0,11391563 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,09081055 0,11385627 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,09081055 0,11379697 ! protein stabilization GO:0050821 39 22 0,000 0,09081055 0,11373773 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,09473793 0,11859494 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09473793 0,11853327 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09473793 0,11847166 ! gluconeogenesis GO:0006094 33 23 0,000 0,09473793 0,11841011 ! viral genome replication GO:0019079 41 23 0,000 0,09473793 0,11834863 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09473793 0,11828722 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09473793 0,11822587 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09473793 0,11816458 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09473793 0,11810335 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09473793 0,11804219 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09473793 0,11798109 ! visual behavior GO:0007632 42 23 0,000 0,09473793 0,11792006 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09473793 0,11785908 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,09473793 0,11779818 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09473793 0,11773733 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09473793 0,11767655 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09473793 0,11761583 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09473793 0,11755517 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,09473793 0,11749457 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09473793 0,11743404 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09473793 0,11737357 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09473793 0,11731316 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09473793 0,11725281 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09473793 0,11719253 ! fatty acid transport GO:0015908 44 23 0,000 0,09473793 0,11713231 ! platelet activation GO:0030168 37 23 0,000 0,09473793 0,11707215 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09473793 0,11701205 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09473793 0,11695201 ! hormone transport GO:0009914 40 23 0,000 0,09473793 0,11689204 ! cell-cell recognition GO:0009988 25 23 0,000 0,09473793 0,11683212 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09473793 0,11677227 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09473793 0,11671248 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,09473793 0,11665275 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09473793 0,11659308 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09473793 0,11653347 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,09864848 0,12128168 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09864848 0,12121974 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,09864848 0,12115786 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09864848 0,12109605 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09864848 0,12103429 ! vesicle docking GO:0048278 47 24 0,000 0,09864848 0,1209726 ! spinal cord development GO:0021510 47 24 0,000 0,09864848 0,12091098 ! vacuole organization GO:0007033 43 24 0,000 0,09864848 0,12084941 ! digestive system process GO:0022600 39 24 0,000 0,09864848 0,12078791 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09864848 0,12072648 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,09864848 0,1206651 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09864848 0,12060379 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,09864848 0,12054253 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09864848 0,12048135 ! membrane depolarization GO:0051899 39 24 0,000 0,09864848 0,12042022 ! pallium development GO:0021543 49 24 0,000 0,09864848 0,12035915 ! pentose metabolic process GO:0019321 35 24 0,000 0,09864848 0,12029815 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,09864848 0,12023721 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09864848 0,12017633 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09864848 0,12011551 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09864848 0,12005476 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09864848 0,11999406 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09864848 0,11993343 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09864848 0,11987285 ! regulation of amine transport GO:0051952 40 24 0,000 0,09864848 0,11981234 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10254227 0,12447866 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10254227 0,12441588 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10254227 0,12435318 ! phototransduction GO:0007602 33 25 0,000 0,10254227 0,12429053 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10254227 0,12422795 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,10254227 0,12416543 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10254227 0,12410297 ! receptor metabolic process GO:0043112 46 25 0,000 0,10254227 0,12404057 ! chromosome condensation GO:0030261 45 25 0,000 0,10254227 0,12397824 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10254227 0,12391597 ! neural crest cell development GO:0014032 54 25 0,000 0,10254227 0,12385376 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10254227 0,12379162 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10254227 0,12372954 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10254227 0,12366752 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10254227 0,12360556 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,10254227 0,12354367 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10254227 0,12348183 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,10254227 0,12342006 ! immunoglobulin production GO:0002377 55 25 0,000 0,10254227 0,12335835 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10254227 0,1232967 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10254227 0,12323511 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10254227 0,12317359 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10254227 0,12311213 ! telomere organization GO:0032200 43 25 0,000 0,10254227 0,12305072 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10254227 0,12298938 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10254227 0,1229281 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10641936 0,12751244 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10641936 0,12744897 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,10641936 0,12738557 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,10641936 0,12732222 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,10641936 0,12725894 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,10641936 0,12719572 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10641936 0,12713257 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10641936 0,12706947 ! tube lumen formation GO:0035148 50 26 0,000 0,10641936 0,12700644 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,10641936 0,12694347 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,10641936 0,12688057 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,10641936 0,12681773 ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,10641936 0,12675494 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,10641936 0,12669223 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,10641936 0,12662957 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,10641936 0,12656697 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10641936 0,12650444 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,10641936 0,12644197 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10641936 0,12637956 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,10641936 0,12631721 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,10641936 0,12625492 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10641936 0,1261927 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,10641936 0,12613054 ! neuron fate commitment GO:0048663 48 27 0,000 0,11027984 0,1306417 ! iron ion transport GO:0006826 59 27 0,000 0,11027984 0,1305774 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,11027984 0,13051317 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,11027984 0,13044901 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,11027984 0,13038491 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,11027984 0,13032087 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,11027984 0,13025689 ! autophagy GO:0006914 41 27 0,000 0,11027984 0,13019298 ! primary neural tube formation GO:0014020 51 27 0,000 0,11027984 0,13012912 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,11027984 0,13006534 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,11027984 0,13000161 ! glutathione metabolic process GO:0006749 39 27 0,000 0,11027984 0,12993795 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,11027984 0,12987434 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,11027984 0,1298108 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,11027984 0,12974733 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,11412376 0,13420418 ! circadian rhythm GO:0007623 50 28 0,000 0,11412376 0,13413862 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11412376 0,13407313 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,11412376 0,13400769 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11412376 0,13394232 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,11412376 0,13387702 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,11412376 0,13381177 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11412376 0,1337466 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,11412376 0,13368148 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,11412376 0,13361643 ! synaptogenesis GO:0007416 42 28 0,000 0,11412376 0,13355144 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,11412376 0,13348652 ! lipid oxidation GO:0034440 43 28 0,000 0,11412376 0,13342165 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11412376 0,13335685 ! translational initiation GO:0006413 65 29 0,000 0,1179512 0,13776242 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,1179512 0,13769558 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,1179512 0,1376288 ! catechol metabolic process GO:0009712 54 29 0,000 0,1179512 0,13756209 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,1179512 0,13749544 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,1179512 0,13742886 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,1179512 0,13736234 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,1179512 0,13729588 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,1179512 0,13722949 ! cell fate determination GO:0001709 60 29 0,000 0,1179512 0,13716316 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,1179512 0,1370969 ! detection of light stimulus GO:0009583 38 29 0,000 0,1179512 0,1370307 ! regulation of coagulation GO:0050818 46 29 0,000 0,1179512 0,13696457 ! phenol metabolic process GO:0018958 55 30 0,000 0,12176223 0,14132172 ! zinc ion transport GO:0006829 45 30 0,000 0,12176223 0,14125358 ! membrane docking GO:0022406 61 30 0,000 0,12176223 0,14118551 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,12176223 0,1411175 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12176223 0,14104956 ! acute-phase response GO:0006953 49 30 0,000 0,12176223 0,14098168 ! myofibril assembly GO:0030239 47 30 0,000 0,12176223 0,14091387 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,12176223 0,14084612 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12176223 0,14077844 ! phospholipid transport GO:0015914 51 30 0,000 0,12176223 0,14071082 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12176223 0,14064327 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12176223 0,14057578 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12176223 0,14050836 ! eye morphogenesis GO:0048592 60 30 0,000 0,12176223 0,140441 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12555692 0,14474842 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,12555692 0,1446791 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12555692 0,14460984 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12555692 0,14454065 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,12555692 0,14447153 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12555692 0,14440247 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,12555692 0,14433347 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12555692 0,14426455 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,12555692 0,14419569 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,12555692 0,14412689 ! peptide transport GO:0015833 55 31 0,000 0,12555692 0,14405816 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,12555692 0,1439895 ! mesoderm formation GO:0001707 69 31 0,000 0,12555692 0,1439209 ! natural killer cell activation GO:0030101 45 31 0,000 0,12555692 0,14385236 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,12555692 0,14378389 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12555692 0,14371549 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,12555692 0,14364715 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,12555692 0,14357888 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,12933535 0,14782938 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,12933535 0,14775919 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,12933535 0,14768906 ! cholesterol transport GO:0030301 56 32 0,000 0,12933535 0,147619 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,12933535 0,147549 ! spliceosome assembly GO:0000245 67 32 0,000 0,12933535 0,14747907 ! spindle organization GO:0007051 46 32 0,000 0,12933535 0,14740921 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,12933535 0,14733942 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,12933535 0,14726969 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,12933535 0,14720002 ! muscle cell development GO:0055001 49 32 0,000 0,12933535 0,14713042 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,12933535 0,14706089 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,12933535 0,14699142 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,12933535 0,14692202 ! BMP signaling pathway GO:0030509 64 32 0,000 0,12933535 0,14685269 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,12933535 0,14678342 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,12933535 0,14671421 ! gene silencing GO:0016458 65 32 0,000 0,12933535 0,14664507 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13309757 0,15083973 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13309757 0,15076871 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13309757 0,15069776 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13309757 0,15062688 ! cell fate specification GO:0001708 52 33 0,000 0,13309757 0,15055606 ! sterol transport GO:0015918 57 33 0,000 0,13309757 0,15048531 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,13309757 0,15041463 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13309757 0,15034401 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13309757 0,15027346 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13309757 0,15020298 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,13684366 0,1543581 ! glial cell differentiation GO:0010001 63 34 0,000 0,13684366 0,15428577 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,13684366 0,15421351 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,13684366 0,15414131 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,13684366 0,15406918 ! mismatch repair GO:0006298 46 34 0,000 0,13684366 0,15399712 ! spermatid development GO:0007286 63 34 0,000 0,13684366 0,15392512 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,13684366 0,15385319 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,13684366 0,15378133 ! negative regulation of secretion GO:0051048 63 35 0,000 0,14057368 0,15789929 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,14057368 0,15782561 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,14057368 0,15775199 ! odontogenesis GO:0042476 66 35 0,000 0,14057368 0,15767845 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,14057368 0,15760497 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,14057368 0,15753157 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,14057368 0,15745823 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,14057368 0,15738496 ! cytokine production GO:0001816 59 35 0,000 0,14057368 0,15731176 ! neural tube formation GO:0001841 67 35 0,000 0,14057368 0,15723862 ! vesicle localization GO:0051648 64 35 0,000 0,14057368 0,15716555 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,14428771 0,16124302 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,14428771 0,16116817 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,14428771 0,16109338 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,14428771 0,16101866 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,14428771 0,16094401 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,14428771 0,16086943 ! regulation of proteolysis GO:0030162 72 36 0,000 0,14428771 0,16079492 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,14428771 0,16072048 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,14428771 0,1606461 ! aerobic respiration GO:0009060 55 36 0,000 0,14428771 0,1605718 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,14428771 0,16049756 ! RNA export from nucleus GO:0006405 56 37 0,000 0,14798581 0,16453506 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,14798581 0,16445906 ! sister chromatid segregation GO:0000819 58 37 0,000 0,14798581 0,16438313 ! actomyosin structure organization GO:0031032 62 37 0,000 0,14798581 0,16430727 ! organic anion transport GO:0015711 68 37 0,000 0,14798581 0,16423149 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,14798581 0,16415577 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,14798581 0,16408012 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,14798581 0,16400454 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,14798581 0,16392903 ! spermatid differentiation GO:0048515 66 37 0,000 0,14798581 0,16385359 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,14798581 0,16377822 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,15166805 0,16777625 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,15166805 0,16769914 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,15166805 0,16762211 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,15166805 0,16754515 ! lipid homeostasis GO:0055088 67 38 0,000 0,15166805 0,16746826 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,15166805 0,16739144 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,15166805 0,16731469 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,15166805 0,16723801 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,15166805 0,1671614 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,15166805 0,16708486 ! glucan metabolic process GO:0044042 62 38 0,000 0,15166805 0,16700839 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,1553345 0,17096744 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1553345 0,17088926 ! segmentation GO:0035282 67 39 0,000 0,1553345 0,17081116 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1553345 0,17073313 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1553345 0,17065517 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1553345 0,17057728 ! RNA modification GO:0009451 57 39 0,000 0,1553345 0,17049946 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,15898523 0,17442702 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,15898523 0,17434752 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,15898523 0,17426809 ! feeding behavior GO:0007631 59 40 0,000 0,15898523 0,17418873 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,15898523 0,17410945 ! maintenance of protein location GO:0045185 91 40 0,000 0,15898523 0,17403024 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1626203 0,17792835 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,1626203 0,17784747 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1626203 0,17776667 ! gliogenesis GO:0042063 88 41 0,000 0,1626203 0,17768594 ! polyol metabolic process GO:0019751 66 41 0,000 0,1626203 0,17760528 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,1626203 0,1775247 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,16623977 0,1813936 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,16623977 0,18131137 ! regulation of tube size GO:0035150 71 42 0,000 0,16623977 0,18122922 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,16623977 0,18114714 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,16623977 0,18106514 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,16623977 0,18098321 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,16623977 0,18090135 ! neuron migration GO:0001764 79 42 0,000 0,16623977 0,18081957 ! regulation of protein secretion GO:0050708 71 42 0,000 0,16623977 0,18073786 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,16984372 0,18457272 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,16984372 0,18448939 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,16984372 0,18440614 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,16984372 0,18432296 ! glucose transport GO:0015758 65 43 0,000 0,16984372 0,18423985 ! neural tube development GO:0021915 77 43 0,000 0,16984372 0,18415683 ! striated muscle contraction GO:0006941 77 43 0,000 0,16984372 0,18407387 ! phagocytosis GO:0006909 90 43 0,000 0,16984372 0,18399099 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,16984372 0,18390819 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,17343222 0,18770936 ! hexose transport GO:0008645 67 44 0,000 0,17343222 0,18762496 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,17343222 0,18754063 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,17343222 0,18745638 ! maintenance of location in cell GO:0051651 97 44 0,000 0,17343222 0,18737221 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,17700531 0,19114667 ! glycolysis GO:0006096 65 45 0,000 0,17700531 0,19106092 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,17700531 0,19097524 ! leukocyte migration GO:0050900 68 45 0,000 0,17700531 0,19088964 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,17700531 0,19080412 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,17700531 0,19071867 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,17700531 0,1906333 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,17700531 0,190548 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,17700531 0,19046278 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,18056309 0,1942042 ! response to insulin stimulus GO:0032868 95 46 0,000 0,18056309 0,19411742 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,18056309 0,19403072 ! positive regulation of defense response GO:0031349 76 47 0,000 0,1841056 0,19774913 ! endosome transport GO:0016197 108 47 0,000 0,1841056 0,19766089 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,1841056 0,19757273 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,1841056 0,19748465 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,1841056 0,19739664 ! JNK cascade GO:0007254 91 47 0,000 0,1841056 0,19730871 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,18763291 0,20099945 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,18763291 0,20091 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,18763291 0,20082063 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,18763291 0,20073134 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,19114509 0,20439781 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,19114509 0,20430701 ! regulation of ion transport GO:0043269 77 49 0,000 0,19114509 0,20421629 ! peptide metabolic process GO:0006518 76 49 0,000 0,19114509 0,20412565 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,19114509 0,20403508 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,19114509 0,2039446 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,19114509 0,2038542 ! neuromuscular process GO:0050905 99 50 0,000 0,1946422 0,20749186 ! inner ear development GO:0048839 79 50 0,000 0,1946422 0,20739997 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,1946422 0,20730816 ! positive regulation of binding GO:0051099 78 51 0,000 0,1981243 0,21092349 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,1981243 0,2108302 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,1981243 0,21073699 ! excretion GO:0007588 83 51 0,000 0,1981243 0,21064387 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,1981243 0,21055083 ! chromatin remodeling GO:0006338 109 51 0,000 0,1981243 0,21045787 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,1981243 0,21036499 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,1981243 0,2102722 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,20159147 0,21385762 ! membrane fusion GO:0006944 110 52 0,000 0,20159147 0,21376337 ! amino acid activation GO:0043038 92 52 0,000 0,20159147 0,2136692 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,20159147 0,21357511 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,20504376 0,21713701 ! RNA catabolic process GO:0006401 93 53 0,000 0,20504376 0,21704148 ! regulation of translational initiation GO:0006446 82 53 0,000 0,20504376 0,21694604 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,20504376 0,21685068 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,20504376 0,2167554 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,20504376 0,21666021 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,20848124 0,22019573 ! cell recognition GO:0008037 85 54 0,000 0,20848124 0,22009911 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,20848124 0,22000257 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,20848124 0,21990612 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,20848124 0,21980976 ! chloride transport GO:0006821 90 55 0,000 0,21190397 0,22332061 ! glucose catabolic process GO:0006007 82 55 0,000 0,21190397 0,22322283 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,21190397 0,22312514 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,21190397 0,22302753 ! gastrulation GO:0007369 112 55 0,000 0,21190397 0,22293001 ! heart morphogenesis GO:0003007 97 55 0,000 0,21190397 0,22283258 ! RNA elongation GO:0006354 79 55 0,000 0,21190397 0,22273523 ! nuclear export GO:0051168 97 55 0,000 0,21190397 0,22263797 ! regulation of actin filament length GO:0030832 105 56 0,000 0,21531201 0,2261199 ! sensory perception of smell GO:0007608 80 56 0,000 0,21531201 0,22602124 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,21531201 0,22592267 ! proton transport GO:0015992 94 56 0,000 0,21531201 0,22582419 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,21531201 0,22572579 ! lipid modification GO:0030258 97 57 0,000 0,21870542 0,22918347 ! maintenance of location GO:0051235 118 57 0,000 0,21870542 0,22908369 ! hydrogen transport GO:0006818 97 58 0,000 0,22208427 0,23252165 ! regulation of endocytosis GO:0030100 91 58 0,000 0,22208427 0,23242051 ! adult behavior GO:0030534 99 58 0,000 0,22208427 0,23231946 ! positive regulation of secretion GO:0051047 95 59 0,000 0,22544862 0,23573637 ! regulation of cellular component size GO:0032535 109 59 0,000 0,22544862 0,23563397 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,22544862 0,23553165 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,22544862 0,23542942 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,22544862 0,23532728 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,22879854 0,23872042 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,22879854 0,23861694 ! regulation of heart contraction GO:0008016 110 60 0,000 0,22879854 0,23851355 ! camera-type eye development GO:0043010 116 60 0,000 0,22879854 0,23841026 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,22879854 0,23830705 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,23213407 0,24167658 ! mesoderm development GO:0007498 119 61 0,000 0,23213407 0,24157205 ! tRNA processing GO:0008033 89 61 0,000 0,23213407 0,24146761 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,23213407 0,24136326 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,23545529 0,24471077 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,23876226 0,24804058 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,23876226 0,24793353 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,24205503 0,25124435 ! single fertilization GO:0007338 75 64 0,000 0,24205503 0,251136 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,24533366 0,25442793 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,24533366 0,25431831 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,24533366 0,25420878 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,24859822 0,25748055 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,24859822 0,25736976 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,25184877 0,26062286 ! activation of MAPK activity GO:0000187 115 67 0,000 0,25184877 0,26051081 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,25184877 0,26039886 ! hexose catabolic process GO:0019320 104 67 0,000 0,25184877 0,260287 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,25184877 0,26017525 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,25184877 0,26006358 ! activation of immune response GO:0002253 105 67 0,000 0,25184877 0,25995201 ! amino acid transport GO:0006865 125 68 0,000 0,25508537 0,26317984 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,25508537 0,26306704 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,25508537 0,26295432 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,25830807 0,2661624 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,25830807 0,26604846 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,25830807 0,26593462 ! antigen processing and presentation GO:0019882 104 69 0,000 0,25830807 0,26582088 ! appendage morphogenesis GO:0035107 135 70 0,000 0,26151693 0,26900801 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,26471202 0,27217825 ! appendage development GO:0048736 136 71 0,000 0,26471202 0,27206199 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 137 71 0,000 0,26471202 0,27194582 ! acute inflammatory response GO:0002526 113 72 0,000 0,26789339 0,27509667 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,26789339 0,27497931 ! carbohydrate transport GO:0008643 110 72 0,000 0,26789339 0,27486204 ! fertilization GO:0009566 90 73 0,000 0,2710611 0,27799361 ! transition metal ion transport GO:0000041 126 74 0,000 0,27421521 0,28110856 ! neurotransmitter transport GO:0006836 123 74 0,000 0,27421521 0,28098884 ! exocytosis GO:0006887 133 74 0,000 0,27421521 0,28086922 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,27421521 0,2807497 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,27421521 0,28063028 ! eye development GO:0001654 143 74 0,000 0,27421521 0,28051097 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,27735577 0,28360306 ! defense response to bacterium GO:0042742 89 76 0,000 0,28048285 0,28667874 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,28048285 0,28655701 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,28048285 0,28643538 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,28359651 0,28949223 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,28359651 0,28936946 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,28359651 0,2892468 ! blood coagulation GO:0007596 146 78 0,000 0,28669679 0,29228495 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,28669679 0,29216115 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,28978376 0,29518193 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,28978376 0,29505701 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,28978376 0,2949322 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,29285747 0,29793449 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,29285747 0,29780856 ! inorganic anion transport GO:0015698 138 80 0,000 0,29285747 0,29768275 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,29591798 0,30066666 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,29896534 0,3036347 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,29896534 0,30350659 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,29896534 0,30337858 ! regulation of lyase activity GO:0051339 160 83 0,000 0,30199962 0,30632845 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,30502086 0,30926262 ! hemostasis GO:0007599 158 84 0,000 0,30502086 0,30913235 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,30502086 0,30900219 ! nucleosome assembly GO:0006334 122 85 0,000 0,30802913 0,31191839 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,30802913 0,31178716 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,31102447 0,31468666 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,31102447 0,31455439 ! chromatin assembly GO:0031497 124 86 0,000 0,31102447 0,31442222 ! alcohol catabolic process GO:0046164 130 86 0,000 0,31102447 0,31429017 ! amine transport GO:0015837 155 86 0,000 0,31102447 0,31415822 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,31400695 0,31703765 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,31400695 0,31690467 ! cellular respiration GO:0045333 135 88 0,000 0,31697662 0,31976761 ! regulation of neurological system process GO:0031644 148 88 0,000 0,31697662 0,31963359 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,31697662 0,31949968 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,32287774 0,32531149 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,32287774 0,32517532 ! sterol metabolic process GO:0016125 152 91 0,000 0,32580929 0,32799044 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,32580929 0,32785327 ! regulation of defense response GO:0031347 149 92 0,000 0,32872826 0,33065225 ! nucleosome organization GO:0034728 138 92 0,000 0,32872826 0,33051408 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,32872826 0,33037602 ! vitamin metabolic process GO:0006766 139 92 0,000 0,32872826 0,33023807 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,33163468 0,3330188 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,33163468 0,33287987 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,33452861 0,33564464 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,34027923 0,34127213 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,34027923 0,34112993 ! positive regulation of immune response GO:0050778 156 96 0,000 0,34027923 0,34098785 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,34313602 0,34370744 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,34598054 0,34641247 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,34598054 0,34626838 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,34881283 0,34895787 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,34881283 0,34881283