pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6556-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of epithelial cell proliferation GO:0050678 71 39 4,000 1,293E-06 2,974E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 3,000 2E-06 2,3E-03 ! activation of MAPKKK activity GO:0000185 10 6 2,000 2,274E-06 1,744E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 6,323E-06 3,636E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 6,323E-06 2,909E-03 ! activation of MAPKK activity GO:0000186 21 14 2,000 4,023E-05 0,01542227 ! cell cycle arrest GO:0007050 150 86 4,000 6,524E-05 0,02143601 ! response to UV GO:0009411 75 46 3,000 7,609E-05 0,02187481 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 1,434E-04 0,03664296 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 1,434E-04 0,03297866 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 1,654E-04 0,03459118 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 1,768E-04 0,03387759 ! negative regulation of kinase activity GO:0033673 100 58 3,000 1,891E-04 0,03346273 ! negative regulation of transferase activity GO:0051348 105 61 3,000 2,3E-04 0,03779337 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,369E-04 0,03632598 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,369E-04 0,03405561 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 2,369E-04 0,03205234 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 2,369E-04 0,03027165 ! microvillus organization GO:0032528 7 5 1,000 2,369E-04 0,02867841 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 1,000 2,369E-04 0,02724449 ! sister chromatid cohesion GO:0007062 9 5 1,000 2,369E-04 0,02594713 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 2,369E-04 0,02476772 ! protein oligomerization GO:0051259 100 65 3,000 2,94E-04 0,02940299 ! regulation of helicase activity GO:0051095 11 6 1,000 3,542E-04 0,03394662 ! male meiosis GO:0007140 7 6 1,000 3,542E-04 0,03258876 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 3,542E-04 0,03133534 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 3,542E-04 0,03017478 ! mRNA stabilization GO:0048255 15 6 1,000 3,542E-04 0,02909711 GO:0043489|RNA stabilization, ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 3,542E-04 0,02809376 ! ER overload response GO:0006983 7 6 1,000 3,542E-04 0,0271573 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 3,542E-04 0,02628126 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 3,542E-04 0,02545997 ! activation of protein kinase activity GO:0032147 102 69 3,000 3,699E-04 0,02577929 ! lymphocyte differentiation GO:0030098 113 71 3,000 4,126E-04 0,02791271 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 4,943E-04 0,03248451 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 4,943E-04 0,03158216 ! T-helper 1 type immune response GO:0042088 11 7 1,000 4,943E-04 0,03072859 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 4,943E-04 0,02991994 ! B cell lineage commitment GO:0002326 17 7 1,000 4,943E-04 0,02915276 ! T cell lineage commitment GO:0002360 12 7 1,000 4,943E-04 0,02842394 ! response to tumor cell GO:0002347 12 7 1,000 4,943E-04 0,02773068 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 5,637E-04 0,03086728 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 6,57E-04 0,03514176 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 6,57E-04 0,03434309 ! induction of positive chemotaxis GO:0050930 14 8 1,000 6,57E-04 0,03357991 ! succinate metabolic process GO:0006105 14 8 1,000 6,57E-04 0,03284991 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 6,57E-04 0,03215097 ! pseudouridine synthesis GO:0001522 9 8 1,000 6,57E-04 0,03148116 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 6,57E-04 0,03083869 ! regulation of vascular permeability GO:0043114 12 8 1,000 6,57E-04 0,03022191 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 6,57E-04 0,02962933 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 6,57E-04 0,02905953 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 6,714E-04 0,02913578 ! protein homooligomerization GO:0051260 52 35 2,000 6,714E-04 0,02859623 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 8,161E-04 0,03412909 ! lung alveolus development GO:0048286 17 9 1,000 8,42E-04 0,03458262 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 8,42E-04 0,03397591 ! phosphagen metabolic process GO:0006599 12 9 1,000 8,42E-04 0,03339011 GO:0006600|creatine metabolic process, ! motor axon guidance GO:0008045 14 9 1,000 8,42E-04 0,03282418 ! detection of calcium ion GO:0005513 13 9 1,000 8,42E-04 0,03227711 ! localization within membrane GO:0051668 15 9 1,000 8,42E-04 0,03174798 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 8,528E-04 0,03163461 ! interphase GO:0051325 159 88 3,000 9,295E-04 0,03393309 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 9,957E-04 0,03578281 ! T cell differentiation GO:0030217 65 40 2,000 9,957E-04 0,0352323 ! B cell differentiation GO:0030183 62 40 2,000 9,957E-04 0,03469848 ! leukocyte differentiation GO:0002521 143 90 3,000 1,011E-03 0,03470325 ! negative regulation of muscle development GO:0048635 12 10 1,000 1,049E-03 0,03548599 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,049E-03 0,0349717 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,049E-03 0,03447211 ! blood vessel remodeling GO:0001974 21 10 1,000 1,049E-03 0,03398658 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,049E-03 0,03351455 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 1,049E-03 0,03305544 ! response to X-ray GO:0010165 16 10 1,000 1,049E-03 0,03260875 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 1,049E-03 0,03217397 ! regulation of bone resorption GO:0045124 24 10 1,000 1,049E-03 0,03175062 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,049E-03 0,03133828 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 1,149E-03 0,03387418 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,231E-03 0,03582673 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,278E-03 0,03674824 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 1,278E-03 0,03629455 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 1,278E-03 0,03585194 ! regulation of mRNA processing GO:0050684 18 11 1,000 1,278E-03 0,03541999 ! mitotic spindle organization GO:0007052 15 11 1,000 1,278E-03 0,03499832 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,278E-03 0,03458658 ! histone deacetylation GO:0016575 13 11 1,000 1,278E-03 0,03418441 ! chromatin silencing GO:0006342 19 11 1,000 1,278E-03 0,03379148 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,278E-03 0,03340749 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 1,278E-03 0,03303212 GO:0042130|negative regulation of T cell proliferation, ! response to light stimulus GO:0009416 153 96 3,000 1,285E-03 0,03284553 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 1,316E-03 0,03326017 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 1,405E-03 0,03512403 ! histone modification GO:0016570 68 46 2,000 1,498E-03 0,03703924 ! histone acetylation GO:0016573 23 12 1,000 1,529E-03 0,03741027 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,529E-03 0,03701648 ! response to gamma radiation GO:0010332 20 12 1,000 1,529E-03 0,03663089 ! regulation of mRNA stability GO:0043488 27 12 1,000 1,529E-03 0,03625325 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 1,529E-03 0,03588332 ! covalent chromatin modification GO:0016569 75 47 2,000 1,594E-03 0,03703554 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 2,000 1,594E-03 0,03666519 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 1,594E-03 0,03630216 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of DNA replication GO:0006275 75 48 2,000 1,694E-03 0,03820731 ! RNA elongation GO:0006354 62 49 2,000 1,799E-03 0,0401617 ! regulation of intracellular transport GO:0032386 78 49 2,000 1,799E-03 0,03977552 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,801E-03 0,03945404 ! regulation of exocytosis GO:0017157 17 13 1,000 1,801E-03 0,03908184 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 1,801E-03 0,03871659 ! regulation of cellular pH GO:0030641 20 13 1,000 1,801E-03 0,0383581 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 1,801E-03 0,03800619 ! regulation of RNA stability GO:0043487 28 13 1,000 1,801E-03 0,03766068 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 2,019E-03 0,04182703 ! positive regulation of cell migration GO:0030335 92 51 2,000 2,019E-03 0,04145357 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 2,095E-03 0,0426345 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,095E-03 0,04226051 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 2,095E-03 0,04189303 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 1,000 2,095E-03 0,04153188 ! cellular response to starvation GO:0009267 21 14 1,000 2,095E-03 0,04117691 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 2,095E-03 0,04082795 ! G1/S transition checkpoint GO:0031575 33 14 1,000 2,095E-03 0,04048486 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,095E-03 0,04014749 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 2,095E-03 0,03981569 ! regulation of bone remodeling GO:0046850 90 53 2,000 2,255E-03 0,04250737 ! regulation of tissue remodeling GO:0034103 91 54 2,000 2,379E-03 0,04448447 ! lipid phosphorylation GO:0046834 23 15 1,000 2,409E-03 0,0446867 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 2,409E-03 0,04432921 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 2,409E-03 0,04397739 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 2,409E-03 0,04363111 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 2,409E-03 0,04329024 ! defense response to virus GO:0051607 27 15 1,000 2,409E-03 0,04295466 ! positive regulation of cell motion GO:0051272 99 56 2,000 2,64E-03 0,0467062 ! protein amino acid deacetylation GO:0006476 20 16 1,000 2,745E-03 0,04818741 ! protein amino acid acetylation GO:0006473 28 16 1,000 2,745E-03 0,04782236 ! G1 phase GO:0051318 27 16 1,000 2,745E-03 0,04746279 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 2,745E-03 0,04710859 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 2,918E-03 0,04971239 ! lung development GO:0030324 94 59 2,000 3,063E-03 0,05180731 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 3,101E-03 0,05205417 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 3,101E-03 0,05167696 ! neuromuscular junction development GO:0007528 23 17 1,000 3,101E-03 0,05130518 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 3,101E-03 0,05093872 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 3,101E-03 0,05057745 ! meiosis GO:0007126 96 61 2,000 3,368E-03 0,05454511 GO:0051327|M phase of meiotic cell cycle, ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 3,477E-03 0,05592507 ! somitogenesis GO:0001756 24 18 1,000 3,477E-03 0,0555367 ! detection of chemical stimulus GO:0009593 26 18 1,000 3,477E-03 0,05515369 ! cellular response to nutrient levels GO:0031669 27 18 1,000 3,477E-03 0,05477593 ! negative regulation of T cell activation GO:0050868 25 18 1,000 3,477E-03 0,0544033 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 3,477E-03 0,05403571 ! negative regulation of cell growth GO:0030308 106 62 2,000 3,526E-03 0,05443348 ! respiratory tube development GO:0030323 99 62 2,000 3,526E-03 0,05407059 ! meiotic cell cycle GO:0051321 97 62 2,000 3,526E-03 0,0537125 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 3,69E-03 0,0558299 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 3,69E-03 0,055465 ! negative regulation of cell size GO:0045792 108 64 2,000 3,857E-03 0,05761148 ! respiratory system development GO:0060541 100 64 2,000 3,857E-03 0,05723979 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 3,874E-03 0,05711329 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 3,874E-03 0,05674951 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 3,874E-03 0,05639034 ! response to starvation GO:0042594 30 19 1,000 3,874E-03 0,05603568 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 3,874E-03 0,05568546 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 3,874E-03 0,05533958 ! regulation of caspase activity GO:0043281 97 65 2,000 4,03E-03 0,05721446 ! B cell activation GO:0042113 104 65 2,000 4,03E-03 0,05686345 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 4,29E-03 0,06017144 ! positive regulation of locomotion GO:0040017 35 20 1,000 4,29E-03 0,05980677 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of osteoblast differentiation GO:0045669 33 20 1,000 4,29E-03 0,05944648 ! positive regulation of B cell activation GO:0050871 31 20 1,000 4,29E-03 0,05909052 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 4,389E-03 0,06008273 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 4,727E-03 0,06433226 ! protein amino acid acylation GO:0043543 37 21 1,000 4,727E-03 0,06395383 ! regulation of chemotaxis GO:0050920 36 21 1,000 4,727E-03 0,06357983 ! cell aging GO:0007569 32 21 1,000 4,727E-03 0,06321018 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 4,727E-03 0,0628448 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 4,727E-03 0,06248363 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 4,962E-03 0,06521643 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 2,000 4,962E-03 0,06484589 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 5,183E-03 0,06735207 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 5,183E-03 0,06697369 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 5,183E-03 0,06659953 ! vasculogenesis GO:0001570 33 22 1,000 5,183E-03 0,06622953 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 5,183E-03 0,06586362 ! regulation of behavior GO:0050795 38 22 1,000 5,183E-03 0,06550174 ! protein tetramerization GO:0051262 39 22 1,000 5,183E-03 0,0651438 ! regulation of peptidase activity GO:0052547 106 72 2,000 5,368E-03 0,06710474 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 5,368E-03 0,06674202 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 2,000 5,368E-03 0,06638319 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 5,659E-03 0,06959975 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 5,659E-03 0,06922954 ! myelination GO:0042552 35 23 1,000 5,659E-03 0,06886324 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 5,659E-03 0,06850081 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 5,659E-03 0,06814216 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 5,659E-03 0,06778726 ! negative regulation of DNA replication GO:0008156 35 23 1,000 5,659E-03 0,06743603 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 5,659E-03 0,06708842 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 5,659E-03 0,06674438 ! response to oxygen levels GO:0070482 137 74 2,000 5,794E-03 0,06799196 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 5,794E-03 0,06764682 ! negative regulation of growth GO:0045926 123 75 2,000 6,014E-03 0,06986343 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 6,154E-03 0,07112165 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 6,154E-03 0,07076604 ! mitochondrial membrane organization GO:0007006 39 24 1,000 6,154E-03 0,07041397 ! negative regulation of cell development GO:0010721 56 24 1,000 6,154E-03 0,07006539 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 6,154E-03 0,06972024 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 6,154E-03 0,06937847 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 6,154E-03 0,06904004 ! neurotransmitter secretion GO:0007269 32 24 1,000 6,154E-03 0,06870489 ! regulation of protein transport GO:0051223 114 76 2,000 6,24E-03 0,06932797 GO:0070201|regulation of establishment of protein localization, ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 6,667E-03 0,07372611 GO:0045936|negative regulation of phosphate metabolic process, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 6,667E-03 0,07337335 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 6,667E-03 0,07302395 ! T cell activation GO:0042110 134 79 2,000 6,945E-03 0,07570477 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 7,2E-03 0,07811401 ! regulation of pH GO:0006885 36 26 1,000 7,2E-03 0,07774728 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 7,2E-03 0,07738398 ! inner ear morphogenesis GO:0042472 35 27 1,000 7,751E-03 0,0829218 ! response to ionizing radiation GO:0010212 47 27 1,000 7,751E-03 0,0825379 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 7,751E-03 0,08215754 ! negative regulation of protein transport GO:0051224 49 27 1,000 7,751E-03 0,08178067 ! gene silencing GO:0016458 41 27 1,000 7,751E-03 0,08140724 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 8,321E-03 0,08699379 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 8,321E-03 0,08660015 ! ensheathment of neurons GO:0007272 43 28 1,000 8,321E-03 0,08621006 GO:0008366|axon ensheathment, ! positive regulation of catabolic process GO:0009896 40 28 1,000 8,321E-03 0,08582347 ! regulation of B cell activation GO:0050864 42 28 1,000 8,321E-03 0,08544033 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 8,494E-03 0,08682362 ! transcription initiation GO:0006352 118 85 2,000 8,494E-03 0,08643944 ! regulation of protein localization GO:0032880 132 85 2,000 8,494E-03 0,08605865 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 8,909E-03 0,08987314 ! tissue homeostasis GO:0001894 42 29 1,000 8,909E-03 0,08948068 GO:0048871|multicellular organismal homeostasis, ! skeletal muscle tissue development GO:0007519 123 87 2,000 9,051E-03 0,09051192 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 9,051E-03 0,09012009 ! spindle organization GO:0007051 37 30 1,000 9,515E-03 0,09433224 ! negative regulation of cell activation GO:0050866 44 30 1,000 9,515E-03 0,09392738 ! response to heat GO:0009408 41 30 1,000 9,515E-03 0,09352598 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,01013922 0,09923494 ! mammary gland development GO:0030879 57 31 1,000 0,01013922 0,09881445 ! segmentation GO:0035282 41 31 1,000 0,01013922 0,09839751 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,01013922 0,09798408 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01013922 0,0975741 ! RNA modification GO:0009451 40 31 1,000 0,01013922 0,09716754 ! regulation of muscle development GO:0048634 48 32 1,000 0,01078089 0,10288813 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,01078089 0,10246298 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,01078089 0,10204132 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01078089 0,10162312 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01078089 0,10120833 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,01078089 0,10079691 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 0,01085046 0,10103663 ! ear morphogenesis GO:0042471 42 33 1,000 0,01144006 0,10609736 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,01144006 0,10567126 ! angiogenesis GO:0001525 149 95 2,000 0,01149287 0,10573439 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,01211657 0,11102829 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,01211657 0,1105877 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,01211657 0,11015059 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,01211657 0,10971693 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,01211657 0,10928667 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,01281021 0,11509175 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01281021 0,11464392 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01352082 0,12053447 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 1,000 0,01352082 0,12006908 ! tissue remodeling GO:0048771 62 36 1,000 0,01352082 0,11960728 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,01424822 0,125559 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,01499222 0,13161107 ! mesenchymal cell development GO:0014031 64 38 1,000 0,01499222 0,13111065 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,01575265 0,13723896 ! chromatin remodeling GO:0006338 68 39 1,000 0,01575265 0,13672108 ! synapse organization GO:0050808 55 39 1,000 0,01575265 0,13620709 ! response to calcium ion GO:0051592 58 40 1,000 0,01652933 0,14238747 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,01652933 0,14185617 ! inner ear development GO:0048839 57 40 1,000 0,01652933 0,14132882 ! double-strand break repair GO:0006302 67 40 1,000 0,01652933 0,14080538 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,01652933 0,14028581 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,01652933 0,13977005 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,01732209 0,145937 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01732209 0,14540439 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,01732209 0,14487564 ! mitochondrial transport GO:0006839 60 42 1,000 0,01813075 0,15108961 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,01813075 0,15054416 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,01813075 0,15000264 ! regulation of cell shape GO:0008360 78 42 1,000 0,01813075 0,14946499 ! positive regulation of binding GO:0051099 59 43 1,000 0,01895515 0,15570304 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,01895515 0,15514894 ! activation of caspase activity GO:0006919 65 43 1,000 0,01895515 0,15459876 ! tRNA processing GO:0008033 49 43 1,000 0,01895515 0,15405248 ! response to insulin stimulus GO:0032868 63 43 1,000 0,01895515 0,15351004 ! regulation of action potential GO:0001508 71 44 1,000 0,01979511 0,15975005 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,01979511 0,15919148 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,02065047 0,16549158 ! regulation of translational initiation GO:0006446 64 45 1,000 0,02065047 0,16491695 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,02065047 0,16434631 ! regulation of ossification GO:0030278 71 46 1,000 0,02152105 0,17068421 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,02240669 0,17709757 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,02240669 0,17649108 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,02330723 0,18295776 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 1,000 0,02330723 0,18233545 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,02330723 0,18171736 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,02330723 0,18110345 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,02422249 0,18758157 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02435868 0,1880032 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02435868 0,18737443 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02435868 0,18674985 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02435868 0,18612941 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02435868 0,18551309 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02435868 0,18490084 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02435868 0,18429261 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02435868 0,18368837 ! sleep GO:0030431 11 5 0,000 0,02435868 0,18308808 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02435868 0,18249171 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02435868 0,1818992 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02435868 0,18131053 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02435868 0,18072566 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02435868 0,18014455 ! tongue development GO:0043586 6 5 0,000 0,02435868 0,17956716 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02435868 0,17899346 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02435868 0,17842342 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02435868 0,177857 ! cobalt ion transport GO:0006824 9 5 0,000 0,02435868 0,17729416 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02435868 0,17673487 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02435868 0,1761791 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02435868 0,17562681 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02435868 0,17507798 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02435868 0,17453257 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02435868 0,17399054 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02435868 0,17345187 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02435868 0,17291652 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02435868 0,17238447 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02435868 0,17185569 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02435868 0,17133013 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02435868 0,17080779 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02435868 0,17028861 ! malate metabolic process GO:0006108 7 5 0,000 0,02435868 0,16977259 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02435868 0,16925968 ! behavioral response to pain GO:0048266 7 5 0,000 0,02435868 0,16874986 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02435868 0,1682431 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02435868 0,16773938 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02435868 0,16723867 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02435868 0,16674093 ! mating behavior GO:0007617 6 5 0,000 0,02435868 0,16624615 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02435868 0,1657543 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02435868 0,16526535 ! rhythmic behavior GO:0007622 12 5 0,000 0,02435868 0,16477928 ! copulation GO:0007620 7 5 0,000 0,02435868 0,16429605 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02435868 0,16381565 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02435868 0,16333806 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02435868 0,16286324 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02435868 0,16239117 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02435868 0,16192183 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02435868 0,1614552 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02435868 0,16099125 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02435868 0,16052995 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02435868 0,1600713 ! response to protozoan GO:0001562 9 5 0,000 0,02435868 0,15961525 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02435868 0,1591618 ! lymph vessel development GO:0001945 7 5 0,000 0,02435868 0,15871092 ! endochondral ossification GO:0001958 12 5 0,000 0,02435868 0,15826258 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02435868 0,15781677 ! parathyroid gland development GO:0060017 8 5 0,000 0,02435868 0,15737347 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02435868 0,15693264 ! anagen GO:0042640 6 5 0,000 0,02435868 0,15649428 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02435868 0,15605837 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02435868 0,15562487 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02435868 0,15519378 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02435868 0,15476507 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02435868 0,15433872 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02435868 0,15391471 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02435868 0,15349302 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02435868 0,15307364 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02435868 0,15265655 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02435868 0,15224172 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02435868 0,15182914 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02435868 0,15141879 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02435868 0,15101066 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02435868 0,15060471 ! ovulation GO:0030728 6 5 0,000 0,02435868 0,15020095 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02435868 0,14979934 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 9 5 0,000 0,02435868 0,14939988 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02435868 0,14900254 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02435868 0,1486073 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02435868 0,14821416 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02435868 0,1478231 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02435868 0,14743409 ! polyol catabolic process GO:0046174 7 5 0,000 0,02435868 0,14704712 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02435868 0,14666218 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02435868 0,14627925 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02435868 0,14589832 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02435868 0,14551936 ! urea metabolic process GO:0019627 6 5 0,000 0,02435868 0,14514237 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02435868 0,14476732 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02435868 0,14439421 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02435868 0,14402302 ! neutrophil activation GO:0042119 5 5 0,000 0,02435868 0,14365373 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02435868 0,14328633 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02435868 0,1429208 ! response to food GO:0032094 5 5 0,000 0,02435868 0,14255713 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02435868 0,14219531 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02435868 0,14183533 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02435868 0,14147716 ! forebrain neuron development GO:0021884 7 5 0,000 0,02435868 0,14112079 ! melanosome organization GO:0032438 7 5 0,000 0,02435868 0,14076621 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02435868 0,14041342 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02435868 0,14006238 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02435868 0,1397131 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02435868 0,13936556 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02435868 0,13901974 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02435868 0,13867563 ! nucleoside transport GO:0015858 6 5 0,000 0,02435868 0,13833322 ! nucleoside salvage GO:0043174 7 5 0,000 0,02435868 0,1379925 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02435868 0,13765345 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02435868 0,13731606 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02435868 0,13698033 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02435868 0,13664623 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02435868 0,13631376 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02435868 0,1359829 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02435868 0,13565364 ! depyrimidination GO:0045008 8 5 0,000 0,02435868 0,13532597 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02435868 0,13499989 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02435868 0,13467537 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02435868 0,13435241 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02435868 0,13403099 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02435868 0,13371111 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02435868 0,13339275 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02435868 0,1330759 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02435868 0,13276055 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02435868 0,1324467 ! monocyte differentiation GO:0030224 8 5 0,000 0,02435868 0,13213432 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02435868 0,13182342 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02435868 0,13151398 ! centrosome duplication GO:0051298 5 5 0,000 0,02435868 0,13120598 ! response to UV-C GO:0010225 6 5 0,000 0,02435868 0,13089942 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02435868 0,1305943 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02435868 0,13029059 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02435868 0,12998829 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02435868 0,12968739 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02435868 0,12938788 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02435868 0,12908975 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02435868 0,128793 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02435868 0,1284976 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02435868 0,12820356 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02435868 0,12791085 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02435868 0,12761948 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02435868 0,12732944 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02435868 0,12704071 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02435868 0,12675329 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02435868 0,12646716 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02435868 0,12618233 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02435868 0,12589877 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02435868 0,12561649 ! neural tube patterning GO:0021532 6 5 0,000 0,02435868 0,12533547 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02435868 0,1250557 ! histone demethylation GO:0016577 9 5 0,000 0,02435868 0,12477718 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02435868 0,1244999 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02435868 0,12422384 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02435868 0,12394901 ! enteric nervous system development GO:0048484 8 5 0,000 0,02435868 0,12367539 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02435868 0,12340298 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02435868 0,12313177 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02435868 0,12286174 ! transcription termination GO:0006353 8 5 0,000 0,02435868 0,1225929 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02435868 0,12232523 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02435868 0,12205872 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02435868 0,12179338 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02435868 0,12152918 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02435868 0,12126613 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02435868 0,12100422 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02435868 0,12074343 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02435868 0,12048377 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02435868 0,12022522 ! apical protein localization GO:0045176 6 5 0,000 0,02435868 0,11996778 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02435868 0,11971144 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02435868 0,11945619 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02435868 0,11920203 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02435868 0,11894895 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02435868 0,11869694 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02435868 0,11844599 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02435868 0,1181961 ! glial cell migration GO:0008347 10 5 0,000 0,02435868 0,11794727 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02435868 0,11769948 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02435868 0,11745273 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02435868 0,11720702 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02435868 0,11696232 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02435868 0,11671865 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02435868 0,11647599 ! neural plate development GO:0001840 6 5 0,000 0,02435868 0,11623434 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02435868 0,11599369 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02435868 0,11575404 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02435868 0,11551537 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02435868 0,11527768 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02435868 0,11504097 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02435868 0,11480523 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02435868 0,11457046 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02435868 0,11433664 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02435868 0,11410378 ! spindle assembly GO:0051225 5 5 0,000 0,02435868 0,11387186 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02435868 0,11364088 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02435868 0,11341084 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02435868 0,11318172 ! organ regeneration GO:0031100 7 5 0,000 0,02435868 0,11295354 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02435868 0,11272626 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02435868 0,11249991 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02435868 0,11227446 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02435868 0,11204991 GO:0055081|anion homeostasis, ! ear development GO:0043583 72 50 1,000 0,02515232 0,11546973 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,02515232 0,11523971 ! lipid modification GO:0030258 73 50 1,000 0,02515232 0,1150106 ! positive regulation of growth GO:0045927 67 50 1,000 0,02515232 0,11478241 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,02515232 0,11455512 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,02609655 0,11862069 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,02609655 0,11838673 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,02609655 0,11815368 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,02705503 0,12225259 ! aging GO:0007568 79 52 1,000 0,02705503 0,12201287 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,02705503 0,1217741 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,02802759 0,12590519 ! cell projection assembly GO:0030031 76 53 1,000 0,02802759 0,12565976 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,02901408 0,12982952 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,02901408 0,12957742 ! tRNA transcription GO:0009304 11 6 0,000 0,02915957 0,12997481 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02915957 0,12972341 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02915957 0,12947297 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02915957 0,12922351 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02915957 0,128975 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02915957 0,12872745 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02915957 0,12848084 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02915957 0,12823518 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02915957 0,12799046 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02915957 0,12774667 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02915957 0,1275038 ! prostate gland development GO:0030850 9 6 0,000 0,02915957 0,12726186 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02915957 0,12702083 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02915957 0,12678072 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02915957 0,12654151 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02915957 0,1263032 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02915957 0,12606579 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02915957 0,12582927 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02915957 0,12559363 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02915957 0,12535888 ! neuron adhesion GO:0007158 9 6 0,000 0,02915957 0,125125 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02915957 0,12489199 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02915957 0,12465985 ! signal peptide processing GO:0006465 8 6 0,000 0,02915957 0,12442857 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02915957 0,12419815 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02915957 0,12396858 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02915957 0,12373985 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02915957 0,12351197 ! opsonization GO:0008228 8 6 0,000 0,02915957 0,12328493 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02915957 0,12305872 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02915957 0,12283333 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02915957 0,12260878 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02915957 0,12238504 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02915957 0,12216211 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02915957 0,12194 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02915957 0,12171869 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02915957 0,12149819 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02915957 0,12127848 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02915957 0,12105957 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02915957 0,12084144 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02915957 0,1206241 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02915957 0,12040754 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02915957 0,12019176 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02915957 0,11997675 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02915957 0,1197625 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02915957 0,11954902 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02915957 0,1193363 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02915957 0,11912433 ! thymic T cell selection GO:0045061 12 6 0,000 0,02915957 0,11891312 ! protein lipoylation GO:0009249 10 6 0,000 0,02915957 0,11870266 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02915957 0,11849293 ! pigment granule organization GO:0048753 11 6 0,000 0,02915957 0,11828395 ! drug transport GO:0015893 6 6 0,000 0,02915957 0,11807571 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02915957 0,11786819 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02915957 0,1176614 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02915957 0,11745534 ! histidine metabolic process GO:0006547 6 6 0,000 0,02915957 0,11725 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02915957 0,11704538 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02915957 0,11684146 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02915957 0,11663826 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02915957 0,11643576 ! adenohypophysis development GO:0021984 10 6 0,000 0,02915957 0,11623397 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02915957 0,11603287 ! hyperosmotic response GO:0006972 8 6 0,000 0,02915957 0,11583247 ! microtubule nucleation GO:0007020 10 6 0,000 0,02915957 0,11563276 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02915957 0,11543374 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02915957 0,1152354 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02915957 0,11503774 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02915957 0,11484075 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02915957 0,11464445 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02915957 0,11444881 ! response to dietary excess GO:0002021 7 6 0,000 0,02915957 0,11425383 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02915957 0,11405952 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02915957 0,11386588 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02915957 0,11367288 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02915957 0,11348054 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02915957 0,11328885 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02915957 0,11309781 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02915957 0,11290741 ! neuron apoptosis GO:0051402 8 6 0,000 0,02915957 0,11271765 ! organic alcohol transport GO:0015850 9 6 0,000 0,02915957 0,11252852 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02915957 0,11234003 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02915957 0,11215217 ! male sex determination GO:0030238 9 6 0,000 0,02915957 0,11196494 ! carnitine transport GO:0015879 8 6 0,000 0,02915957 0,11177833 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02915957 0,11159235 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02915957 0,11140698 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02915957 0,11122222 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02915957 0,11103808 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02915957 0,11085455 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02915957 0,11067162 ! parturition GO:0007567 12 6 0,000 0,02915957 0,11048929 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02915957 0,11030757 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02915957 0,11012644 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02915957 0,1099459 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02915957 0,10976596 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02915957 0,1095866 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02915957 0,10940783 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02915957 0,10922964 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02915957 0,10905203 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02915957 0,108875 ! macrophage differentiation GO:0030225 10 6 0,000 0,02915957 0,10869854 ! astrocyte development GO:0014002 14 6 0,000 0,02915957 0,10852265 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02915957 0,10834734 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02915957 0,10817258 ! interaction with symbiont GO:0051702 8 6 0,000 0,02915957 0,10799839 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02915957 0,10782476 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02915957 0,10765169 ! eating behavior GO:0042755 6 6 0,000 0,02915957 0,10747917 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02915957 0,1073072 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02915957 0,10713578 ! response to copper ion GO:0046688 9 6 0,000 0,02915957 0,10696491 ! DNA topological change GO:0006265 8 6 0,000 0,02915957 0,10679459 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02915957 0,1066248 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02915957 0,10645556 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02915957 0,10628685 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02915957 0,10611867 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02915957 0,10595103 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02915957 0,10578391 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02915957 0,10561732 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02915957 0,10545126 ! gas homeostasis GO:0033483 11 6 0,000 0,02915957 0,10528572 ! hair follicle maturation GO:0048820 7 6 0,000 0,02915957 0,10512069 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02915957 0,10495618 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02915957 0,10479219 ! Schwann cell development GO:0014044 14 6 0,000 0,02915957 0,10462871 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02915957 0,10446573 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02915957 0,10430327 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02915957 0,10414131 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02915957 0,10397985 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02915957 0,10381889 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02915957 0,10365842 ! histone ubiquitination GO:0016574 7 6 0,000 0,02915957 0,10349846 ! regulation of meiosis GO:0040020 10 6 0,000 0,02915957 0,10333898 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02915957 0,10318 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02915957 0,10302151 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02915957 0,1028635 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02915957 0,10270597 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02915957 0,10254893 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02915957 0,10239237 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02915957 0,10223628 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02915957 0,10208067 ! receptor internalization GO:0031623 9 6 0,000 0,02915957 0,10192553 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02915957 0,10177087 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02915957 0,10161667 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02915957 0,10146294 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02915957 0,10130967 ! protein deubiquitination GO:0016579 8 6 0,000 0,02915957 0,10115686 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02915957 0,10100452 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02915957 0,10085263 ! axonal fasciculation GO:0007413 9 6 0,000 0,02915957 0,1007012 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02915957 0,10055023 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02915957 0,1003997 ! midbrain development GO:0030901 6 6 0,000 0,02915957 0,10024963 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02915957 0,1001 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02915957 0,09995082 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02915957 0,09980208 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02915957 0,09965379 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02915957 0,09950594 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02915957 0,09935852 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02915957 0,09921154 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02915957 0,09906499 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02915957 0,09891888 ! adult feeding behavior GO:0008343 6 6 0,000 0,02915957 0,0987732 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02915957 0,09862794 ! blastocyst growth GO:0001832 15 6 0,000 0,02915957 0,09848311 ! pigment granule transport GO:0051904 12 6 0,000 0,02915957 0,09833871 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02915957 0,09819473 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02915957 0,09805117 ! catecholamine transport GO:0051937 7 6 0,000 0,02915957 0,09790803 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02915957 0,09776531 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02915957 0,097623 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02915957 0,09748111 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02915957 0,09733962 ! protein prenylation GO:0018342 10 6 0,000 0,02915957 0,09719855 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02915957 0,09705789 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02915957 0,09691763 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02915957 0,09677778 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02915957 0,09663833 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,0310282 0,10268324 ! chromosome segregation GO:0007059 83 57 1,000 0,03205552 0,1059306 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,03205552 0,10577862 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0339371 0,11182714 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0339371 0,11166715 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0339371 0,11150763 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0339371 0,11134856 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0339371 0,11118994 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0339371 0,11103178 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0339371 0,11087406 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0339371 0,1107168 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0339371 0,11055997 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0339371 0,11040359 ! reproductive behavior GO:0019098 12 7 0,000 0,0339371 0,11024766 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0339371 0,11009216 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,0339371 0,1099371 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0339371 0,10978248 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0339371 0,10962829 ! oligopeptide transport GO:0006857 11 7 0,000 0,0339371 0,10947453 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0339371 0,10932121 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0339371 0,10916831 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0339371 0,10901584 ! RNA methylation GO:0001510 11 7 0,000 0,0339371 0,10886379 ! pericardium development GO:0060039 8 7 0,000 0,0339371 0,10871217 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0339371 0,10856097 ! fibril organization GO:0043206 13 7 0,000 0,0339371 0,1084102 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0339371 0,10825983 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,0339371 0,10810989 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0339371 0,10796036 ! lipoprotein transport GO:0042953 9 7 0,000 0,0339371 0,10781124 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0339371 0,10766254 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0339371 0,10751424 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0339371 0,10736636 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0339371 0,10721887 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0339371 0,1070718 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0339371 0,10692512 ! chemosensory behavior GO:0007635 9 7 0,000 0,0339371 0,10677885 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0339371 0,10663298 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0339371 0,1064875 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0339371 0,10634243 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0339371 0,10619774 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0339371 0,10605345 ! reflex GO:0060004 12 7 0,000 0,0339371 0,10590955 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0339371 0,10576604 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0339371 0,10562292 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0339371 0,10548019 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0339371 0,10533784 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0339371 0,10519588 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0339371 0,10505429 ! spinal cord patterning GO:0021511 7 7 0,000 0,0339371 0,10491309 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0339371 0,10477227 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0339371 0,10463182 ! adrenal gland development GO:0030325 17 7 0,000 0,0339371 0,10449175 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0339371 0,10435206 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0339371 0,10421274 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0339371 0,10407379 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0339371 0,10393521 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0339371 0,103797 ! endosome organization GO:0007032 10 7 0,000 0,0339371 0,10365915 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0339371 0,10352167 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0339371 0,10338456 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0339371 0,10324781 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0339371 0,10311141 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0339371 0,10297538 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0339371 0,10283971 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0339371 0,1027044 ! galactose metabolic process GO:0006012 10 7 0,000 0,0339371 0,10256944 ! vesicle fusion GO:0006906 15 7 0,000 0,0339371 0,10243483 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0339371 0,10230058 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0339371 0,10216668 ! organ growth GO:0035265 11 7 0,000 0,0339371 0,10203313 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0339371 0,10189992 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0339371 0,10176707 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0339371 0,10163456 ! retinol metabolic process GO:0042572 9 7 0,000 0,0339371 0,10150239 ! behavioral fear response GO:0001662 13 7 0,000 0,0339371 0,10137057 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0339371 0,10123909 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0339371 0,10110795 ! rRNA modification GO:0000154 12 7 0,000 0,0339371 0,10097716 ! protein heterooligomerization GO:0051291 10 7 0,000 0,0339371 0,10084669 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0339371 0,10071657 ! response to UV-B GO:0010224 11 7 0,000 0,0339371 0,10058678 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0339371 0,10045732 ! intermediate filament organization GO:0045109 11 7 0,000 0,0339371 0,1003282 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0339371 0,10019941 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0339371 0,10007095 ! fibrinolysis GO:0042730 9 7 0,000 0,0339371 0,09994282 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0339371 0,09981501 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0339371 0,09968754 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0339371 0,09956038 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0339371 0,09943356 ! response to tropane GO:0014073 13 7 0,000 0,0339371 0,09930705 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0339371 0,09918087 ! melanosome localization GO:0032400 10 7 0,000 0,0339371 0,099055 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0339371 0,09892946 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0339371 0,09880423 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0339371 0,09867932 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0339371 0,09855472 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0339371 0,09843044 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0339371 0,09830647 ! mast cell activation GO:0045576 9 7 0,000 0,0339371 0,09818282 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0339371 0,09805947 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0339371 0,09793644 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0339371 0,09781371 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0339371 0,09769129 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0339371 0,09756918 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0339371 0,09744737 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0339371 0,09732586 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0339371 0,09720466 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0339371 0,09708376 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0339371 0,09696316 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0339371 0,09684285 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0339371 0,09672285 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0339371 0,09660314 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0339371 0,09648373 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0339371 0,09636462 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0339371 0,0962458 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0339371 0,09612727 ! diuresis GO:0030146 12 7 0,000 0,0339371 0,09600903 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0339371 0,09589108 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0339371 0,09577342 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0339371 0,09565606 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0339371 0,09553897 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0339371 0,09542218 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0339371 0,09530567 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0339371 0,09518944 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0339371 0,0950735 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0339371 0,09495784 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0339371 0,09484246 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0339371 0,09472736 ! lymph node development GO:0048535 9 7 0,000 0,0339371 0,09461253 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0339371 0,09449799 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0339371 0,09438373 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0339371 0,09426974 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0339371 0,09415602 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0339371 0,09404258 ! ATP catabolic process GO:0006200 10 7 0,000 0,0339371 0,09392941 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0339371 0,09381652 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0339371 0,09370389 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0339371 0,09359154 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0339371 0,09347945 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0339371 0,09336763 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0339371 0,09325608 ! muscle adaptation GO:0043500 12 7 0,000 0,0339371 0,0931448 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0339371 0,09303378 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0339371 0,09292302 ! retina homeostasis GO:0001895 9 7 0,000 0,0339371 0,09281253 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0339371 0,09270231 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0339371 0,09259234 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0339371 0,09248263 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0339371 0,09237318 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0339371 0,092264 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0339371 0,09215507 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0339371 0,09204639 ! activation of MAPK activity GO:0000187 84 59 1,000 0,03414993 0,09251454 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,03521671 0,09529229 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,03521671 0,09518031 GO:0035113|embryonic appendage morphogenesis, ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,03521671 0,09506859 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,03521671 0,09495714 ! neurotransmitter transport GO:0006836 81 62 1,000 0,03738868 0,10069551 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,03849357 0,10354995 GO:0090046|regulation of transcription regulator activity, ! regulation of lipase activity GO:0060191 109 63 1,000 0,03849357 0,10342898 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03869141 0,10383925 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03869141 0,10371822 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,03869141 0,10359748 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03869141 0,10347702 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03869141 0,10335683 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03869141 0,10323693 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03869141 0,1031173 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03869141 0,10299795 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03869141 0,10287888 ! phosphate transport GO:0006817 10 8 0,000 0,03869141 0,10276008 ! N-glycan processing GO:0006491 12 8 0,000 0,03869141 0,10264156 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03869141 0,10252331 ! UTP metabolic process GO:0046051 8 8 0,000 0,03869141 0,10240533 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03869141 0,10228762 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03869141 0,10217019 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03869141 0,10205302 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03869141 0,10193612 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03869141 0,10181949 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,03869141 0,10170312 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,03869141 0,10158702 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,03869141 0,10147119 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03869141 0,10135562 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03869141 0,10124031 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03869141 0,10112526 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03869141 0,10101048 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03869141 0,10089596 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03869141 0,10078169 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03869141 0,10066768 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03869141 0,10055394 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03869141 0,10044044 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03869141 0,10032721 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03869141 0,10021423 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03869141 0,1001015 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03869141 0,09998903 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03869141 0,0998768 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03869141 0,09976484 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03869141 0,09965312 ! melanin metabolic process GO:0006582 12 8 0,000 0,03869141 0,09954165 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03869141 0,09943043 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03869141 0,09931946 ! macrophage activation GO:0042116 12 8 0,000 0,03869141 0,09920873 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03869141 0,09909826 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03869141 0,09898802 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03869141 0,09887804 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03869141 0,09876829 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03869141 0,0986588 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03869141 0,09854954 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03869141 0,09844052 ! ruffle organization GO:0031529 11 8 0,000 0,03869141 0,09833175 ! osteoblast development GO:0002076 13 8 0,000 0,03869141 0,09822322 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03869141 0,09811492 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03869141 0,09800686 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03869141 0,09789905 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03869141 0,09779146 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03869141 0,09768412 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03869141 0,09757701 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03869141 0,09747013 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03869141 0,09736349 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03869141 0,09725709 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03869141 0,09715091 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03869141 0,09704497 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03869141 0,09693925 ! segment specification GO:0007379 10 8 0,000 0,03869141 0,09683377 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03869141 0,09672851 ! cellular extravasation GO:0045123 11 8 0,000 0,03869141 0,09662349 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03869141 0,09651869 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03869141 0,09641412 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03869141 0,09630978 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03869141 0,09620566 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03869141 0,09610176 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03869141 0,09599809 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03869141 0,09589465 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03869141 0,09579142 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03869141 0,09568842 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03869141 0,09558564 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03869141 0,09548308 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03869141 0,09538074 ! icosanoid secretion GO:0032309 12 8 0,000 0,03869141 0,09527862 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03869141 0,09517672 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03869141 0,09507504 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03869141 0,09497357 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03869141 0,09487232 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03869141 0,09477128 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03869141 0,09467046 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03869141 0,09456985 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03869141 0,09446946 ! sterol catabolic process GO:0016127 9 8 0,000 0,03869141 0,09436928 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03869141 0,09426931 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03869141 0,09416956 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03869141 0,09407001 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03869141 0,09397068 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03869141 0,09387155 ! prophase GO:0051324 11 8 0,000 0,03869141 0,09377264 ! S phase GO:0051320 8 8 0,000 0,03869141 0,09367393 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03869141 0,09357543 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03869141 0,09347714 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03869141 0,09337905 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03869141 0,09328117 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03869141 0,09318349 ! hormone catabolic process GO:0042447 13 8 0,000 0,03869141 0,09308602 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03869141 0,09298875 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03869141 0,09289168 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03869141 0,09279482 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03869141 0,09269816 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03869141 0,0926017 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,03869141 0,09250544 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03869141 0,09240938 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03869141 0,09231352 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03869141 0,09221786 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03869141 0,09212239 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03869141 0,09202713 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03869141 0,09193206 ! regulation of embryonic development GO:0045995 16 8 0,000 0,03869141 0,09183719 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03869141 0,09174251 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03869141 0,09164803 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,03961086 0,0937294 ! appendage morphogenesis GO:0035107 93 64 1,000 0,03961086 0,09363307 GO:0035108|limb morphogenesis, ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,03961086 0,09353694 ! adaptive immune response GO:0002250 94 64 1,000 0,03961086 0,093441 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 94 65 1,000 0,04074041 0,09600713 GO:0060173|limb development, ! axon guidance GO:0007411 99 66 1,000 0,04188209 0,09859652 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,04342258 0,10211854 ! regulation of developmental growth GO:0048638 13 9 0,000 0,04342258 0,10201423 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,04342258 0,10191014 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04342258 0,10180625 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,04342258 0,10170258 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04342258 0,10159912 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04342258 0,10149587 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,04342258 0,10139283 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04342258 0,10128999 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04342258 0,10118737 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,04342258 0,10108495 ! GTP metabolic process GO:0046039 9 9 0,000 0,04342258 0,10098274 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04342258 0,10088074 ! social behavior GO:0035176 14 9 0,000 0,04342258 0,10077894 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,04342258 0,10067735 ! artery development GO:0060840 19 9 0,000 0,04342258 0,10057597 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04342258 0,10047478 ! regulation of glycolysis GO:0006110 15 9 0,000 0,04342258 0,1003738 ! response to pain GO:0048265 16 9 0,000 0,04342258 0,10027303 ! protein complex disassembly GO:0043241 17 9 0,000 0,04342258 0,10017245 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04342258 0,10007208 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04342258 0,09997191 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,04342258 0,09987193 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04342258 0,09977216 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04342258 0,09967259 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04342258 0,09957321 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04342258 0,09947404 ! protein targeting to ER GO:0045047 19 9 0,000 0,04342258 0,09937506 ! T cell selection GO:0045058 18 9 0,000 0,04342258 0,09927628 ! endoderm development GO:0007492 12 9 0,000 0,04342258 0,09917769 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04342258 0,0990793 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,04342258 0,0989811 ! arginine catabolic process GO:0006527 10 9 0,000 0,04342258 0,0988831 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04342258 0,0987853 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04342258 0,09868768 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,04342258 0,09859026 ! V(D)J recombination GO:0033151 12 9 0,000 0,04342258 0,09849303 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,04342258 0,09839599 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04342258 0,09829915 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04342258 0,09820249 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04342258 0,09810603 ! mannose metabolic process GO:0006013 9 9 0,000 0,04342258 0,09800975 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04342258 0,09791366 ! receptor clustering GO:0043113 15 9 0,000 0,04342258 0,09781776 ! epithelial cell development GO:0002064 10 9 0,000 0,04342258 0,09772205 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04342258 0,09762652 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04342258 0,09753119 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,04342258 0,09743603 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04342258 0,09734107 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04342258 0,09724628 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04342258 0,09715169 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,04342258 0,09705727 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,04342258 0,09696304 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,04342258 0,096869 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04342258 0,09677513 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04342258 0,09668145 ! DNA ligation GO:0006266 14 9 0,000 0,04342258 0,09658794 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04342258 0,09649462 ! response to amine stimulus GO:0014075 13 9 0,000 0,04342258 0,09640148 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04342258 0,09630852 ! erythrocyte development GO:0048821 11 9 0,000 0,04342258 0,09621574 ! renal water homeostasis GO:0003091 14 9 0,000 0,04342258 0,09612313 ! postreplication repair GO:0006301 11 9 0,000 0,04342258 0,09603071 ! mRNA cleavage GO:0006379 13 9 0,000 0,04342258 0,09593846 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04342258 0,09584639 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,04342258 0,09575449 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,04342258 0,09566277 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04342258 0,09557123 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04342258 0,09547986 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04342258 0,09538867 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,04342258 0,09529765 ! acid secretion GO:0046717 14 9 0,000 0,04342258 0,0952068 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04342258 0,09511613 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04342258 0,09502563 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04342258 0,0949353 ! purine base metabolic process GO:0006144 18 9 0,000 0,04342258 0,09484514 ! oocyte differentiation GO:0009994 12 9 0,000 0,04342258 0,09475516 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,04342258 0,09466534 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,04342258 0,0945757 ! spleen development GO:0048536 15 9 0,000 0,04342258 0,09448622 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,04342258 0,09439691 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04342258 0,09430778 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04342258 0,09421881 ! blastocyst formation GO:0001825 12 9 0,000 0,04342258 0,09413 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04342258 0,09404137 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,04342258 0,0939529 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04342258 0,0938646 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04342258 0,09377646 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04342258 0,09368849 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04342258 0,09360069 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04342258 0,09351305 ! prepulse inhibition GO:0060134 14 9 0,000 0,04342258 0,09342557 ! embryonic placenta development GO:0001892 12 9 0,000 0,04342258 0,09333826 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,04342258 0,09325111 ! insulin secretion GO:0030073 17 9 0,000 0,04342258 0,09316412 ! sequestering of metal ion GO:0051238 11 9 0,000 0,04342258 0,09307729 ! response to nicotine GO:0035094 16 9 0,000 0,04342258 0,09299063 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04342258 0,09290412 ! nucleus localization GO:0051647 15 9 0,000 0,04342258 0,09281778 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04342258 0,0927316 ! learning or memory GO:0007611 123 68 1,000 0,0442012 0,09430684 ! response to drug GO:0042493 108 69 1,000 0,04537837 0,09672868 ! response to metal ion GO:0010038 103 70 1,000 0,04656708 0,09917064 ! regulation of catabolic process GO:0009894 106 70 1,000 0,04656708 0,0990789 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,04776721 0,10153842 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,04813074 0,10221671 ! neuron fate specification GO:0048665 11 10 0,000 0,04813074 0,10212242 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,04813074 0,10202829 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,04813074 0,10193435 ! thyroid gland development GO:0030878 19 10 0,000 0,04813074 0,10184057 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,04813074 0,10174697 ! synapsis GO:0007129 13 10 0,000 0,04813074 0,10165353 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,04813074 0,10156027 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,04813074 0,10146719 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,04813074 0,10137427 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,04813074 0,10128152 ! sulfate transport GO:0008272 12 10 0,000 0,04813074 0,10118894 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,04813074 0,10109653 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,04813074 0,10100429 ! androgen metabolic process GO:0008209 13 10 0,000 0,04813074 0,10091221 ! phospholipid efflux GO:0033700 16 10 0,000 0,04813074 0,10082031 ! hippocampus development GO:0021766 19 10 0,000 0,04813074 0,10072857 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,04813074 0,100637 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,04813074 0,10054559 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,04813074 0,10045435 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,04813074 0,10036328 ! pathogenesis GO:0009405 13 10 0,000 0,04813074 0,10027237 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,04813074 0,10018163 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04813074 0,10009105 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,04813074 0,10000063 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,04813074 0,09991038 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,04813074 0,09982029 ! melanocyte differentiation GO:0030318 15 10 0,000 0,04813074 0,09973036 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,04813074 0,09964059 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,04813074 0,09955099 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04813074 0,09946154 ! B cell proliferation GO:0042100 14 10 0,000 0,04813074 0,09937226 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,04813074 0,09928314 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,04813074 0,09919417 ! forebrain cell migration GO:0021885 17 10 0,000 0,04813074 0,09910537 ! lipid digestion GO:0044241 15 10 0,000 0,04813074 0,09901673 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,04813074 0,09892824 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,04813074 0,09883991 ! UV protection GO:0009650 14 10 0,000 0,04813074 0,09875174 ! entry into host cell GO:0030260 20 10 0,000 0,04813074 0,09866372 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,04813074 0,09857587 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,04813074 0,09848817 ! negative regulation of ossification GO:0030279 19 10 0,000 0,04813074 0,09840062 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,04813074 0,09831323 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,04813074 0,098226 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,04813074 0,09813892 ! regulation of organ growth GO:0046620 11 10 0,000 0,04813074 0,09805199 ! response to dsRNA GO:0043331 18 10 0,000 0,04813074 0,09796522 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,04813074 0,0978786 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04813074 0,09779214 ! embryonic axis specification GO:0000578 12 10 0,000 0,04813074 0,09770582 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,04813074 0,09761966 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,04813074 0,09753366 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,04813074 0,0974478 ! cranial nerve development GO:0021545 12 10 0,000 0,04813074 0,09736209 ! fucose catabolic process GO:0019317 16 10 0,000 0,04813074 0,09727654 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,04813074 0,09719113 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,04813074 0,09710588 ! protein sumoylation GO:0016925 12 10 0,000 0,04813074 0,09702077 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,04813074 0,09693581 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04813074 0,09685101 ! zymogen activation GO:0031638 14 10 0,000 0,04813074 0,09676635 ! salivary gland development GO:0007431 22 10 0,000 0,04813074 0,09668183 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04813074 0,09659747 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,04813074 0,09651325 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,04813074 0,09642918 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,04813074 0,09634526 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,04813074 0,09626148 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04813074 0,09617784 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,04813074 0,09609436 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,04813074 0,09601101 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,04813074 0,09592782 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,04813074 0,09584476 ! detection of bacterium GO:0016045 10 10 0,000 0,04813074 0,09576185 ! embryonic gut development GO:0048566 11 10 0,000 0,04813074 0,09567908 ! activation of innate immune response GO:0002218 10 10 0,000 0,04813074 0,09559646 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,04813074 0,09551398 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,04813074 0,09543164 ! developmental induction GO:0031128 13 10 0,000 0,04813074 0,09534944 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,04813074 0,09526738 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,04813074 0,09518547 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,04813074 0,09510369 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,04813074 0,09502206 ! negative regulation of transport GO:0051051 116 73 1,000 0,05020113 0,09902453 ! mitochondrion organization GO:0007005 104 73 1,000 0,05020113 0,09893967 ! protein import into nucleus GO:0006606 118 74 1,000 0,05143466 0,101284 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,05143466 0,10119736 ! response to inorganic substance GO:0010035 115 75 1,000 0,05267905 0,10355711 ! nuclear import GO:0051170 121 75 1,000 0,05267905 0,10346868 ! rRNA transcription GO:0009303 17 11 0,000 0,05281599 0,10364913 ! respiratory burst GO:0045730 14 11 0,000 0,05281599 0,10356077 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,05281599 0,10347256 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05281599 0,1033845 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,05281599 0,10329658 ! virus-host interaction GO:0019048 17 11 0,000 0,05281599 0,10320882 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,05281599 0,10312121 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,05281599 0,10303374 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05281599 0,10294643 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05281599 0,10285926 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,05281599 0,10277224 ! mating GO:0007618 14 11 0,000 0,05281599 0,10268536 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05281599 0,10259863 ! T cell proliferation GO:0042098 20 11 0,000 0,05281599 0,10251205 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05281599 0,10242562 ! bone resorption GO:0045453 16 11 0,000 0,05281599 0,10233933 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05281599 0,10225318 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05281599 0,10216719 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05281599 0,10208133 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05281599 0,10199562 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05281599 0,10191005 ! syncytium formation GO:0006949 15 11 0,000 0,05281599 0,10182463 ! plasma membrane organization GO:0007009 18 11 0,000 0,05281599 0,10173935 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05281599 0,10165421 ! focal adhesion formation GO:0048041 24 11 0,000 0,05281599 0,10156922 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05281599 0,10148436 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05281599 0,10139965 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05281599 0,10131508 ! adult heart development GO:0007512 11 11 0,000 0,05281599 0,10123065 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,05281599 0,10114636 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,05281599 0,10106222 ! temperature homeostasis GO:0001659 16 11 0,000 0,05281599 0,10097821 ! L-glutamate transport GO:0015813 16 11 0,000 0,05281599 0,10089434 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05281599 0,10081061 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05281599 0,10072702 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05281599 0,10064357 ! stem cell development GO:0048864 29 11 0,000 0,05281599 0,10056025 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05281599 0,10047707 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05281599 0,10039404 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,05281599 0,10031113 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05281599 0,10022837 ! vasoconstriction GO:0042310 15 11 0,000 0,05281599 0,10014574 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05281599 0,10006325 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05281599 0,09998089 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05281599 0,09989867 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05281599 0,09981658 ! ribosome assembly GO:0042255 13 11 0,000 0,05281599 0,09973463 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05281599 0,09965282 GO:0006809|nitric oxide biosynthetic process, ! nucleosome positioning GO:0016584 13 11 0,000 0,05281599 0,09957113 ! T cell homeostasis GO:0043029 20 11 0,000 0,05281599 0,09948958 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05281599 0,09940817 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05281599 0,09932689 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05281599 0,09924574 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05281599 0,09916472 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,05281599 0,09908384 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05281599 0,09900308 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05281599 0,09892246 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05281599 0,09884197 ! male genitalia development GO:0030539 13 11 0,000 0,05281599 0,09876161 ! cholesterol efflux GO:0033344 19 11 0,000 0,05281599 0,09868138 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05281599 0,09860128 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,05281599 0,09852132 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05281599 0,09844148 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,05281599 0,09836177 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,05281599 0,09828219 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05281599 0,09820273 ! defense response to fungus GO:0050832 12 11 0,000 0,05281599 0,09812341 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05281599 0,09804422 ! lysogeny GO:0030069 18 11 0,000 0,05281599 0,09796515 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05281599 0,09788621 ! acrosome reaction GO:0007340 13 11 0,000 0,05281599 0,09780739 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05281599 0,09772871 ! tRNA metabolic process GO:0006399 95 76 1,000 0,05393417 0,09971752 ! response to unfolded protein GO:0006986 99 76 1,000 0,05393417 0,09963743 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,05393417 0,09955746 ! regulation of DNA binding GO:0051101 119 77 1,000 0,05519989 0,10181215 ! gland development GO:0048732 148 77 1,000 0,05519989 0,10173057 ! protein ubiquitination GO:0016567 125 77 1,000 0,05519989 0,10164912 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,05647608 0,10391598 ! lactation GO:0007595 20 12 0,000 0,05747845 0,10567581 ! reproductive cellular process GO:0048610 14 12 0,000 0,05747845 0,10559141 ! tRNA modification GO:0006400 14 12 0,000 0,05747845 0,10550713 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,05747845 0,105423 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,05747845 0,105339 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,05747845 0,10525513 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,05747845 0,10517139 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,05747845 0,10508779 ! non-recombinational repair GO:0000726 19 12 0,000 0,05747845 0,10500432 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,05747845 0,10492098 ! peroxisomal transport GO:0043574 21 12 0,000 0,05747845 0,10483778 ! cartilage condensation GO:0001502 18 12 0,000 0,05747845 0,10475471 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,05747845 0,10467177 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,05747845 0,10458896 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,05747845 0,10450628 ! heart looping GO:0001947 15 12 0,000 0,05747845 0,10442373 ! palate development GO:0060021 15 12 0,000 0,05747845 0,10434131 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,05747845 0,10425902 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,05747845 0,10417686 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,05747845 0,10409483 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,05747845 0,10401293 ! arginine metabolic process GO:0006525 13 12 0,000 0,05747845 0,10393116 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,05747845 0,10384952 ! methionine metabolic process GO:0006555 13 12 0,000 0,05747845 0,10376801 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,05747845 0,10368662 ! Golgi organization GO:0007030 18 12 0,000 0,05747845 0,10360536 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,05747845 0,10352423 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,05747845 0,10344322 ! monoamine transport GO:0015844 13 12 0,000 0,05747845 0,10336234 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05747845 0,10328159 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,05747845 0,10320097 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,05747845 0,10312047 ! L-amino acid transport GO:0015807 20 12 0,000 0,05747845 0,10304009 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,05747845 0,10295984 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,05747845 0,10287972 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,05747845 0,10279972 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05747845 0,10271984 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,05747845 0,10264009 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,05747845 0,10256046 ! cerebellum development GO:0021549 13 12 0,000 0,05747845 0,10248096 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,05747845 0,10240158 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,05747845 0,10232232 ! histone methylation GO:0016571 15 12 0,000 0,05747845 0,10224319 ! autonomic nervous system development GO:0048483 23 12 0,000 0,05747845 0,10216417 ! gland morphogenesis GO:0022612 23 12 0,000 0,05747845 0,10208528 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,05747845 0,10200651 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,05747845 0,10192786 ! regulation of epidermis development GO:0045682 17 12 0,000 0,05747845 0,10184934 ! intestinal absorption GO:0050892 19 12 0,000 0,05747845 0,10177093 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,05747845 0,10169265 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,05747845 0,10161448 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,05747845 0,10153644 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,05747845 0,10145851 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,05747845 0,1013807 ! microspike assembly GO:0030035 23 12 0,000 0,05747845 0,10130302 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,05747845 0,10122545 ! response to cold GO:0009409 14 12 0,000 0,05747845 0,101148 ! protein localization in nucleus GO:0034504 133 80 1,000 0,05905932 0,10385049 ! response to protein stimulus GO:0051789 111 81 1,000 0,06036612 0,10606729 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,06036612 0,10598632 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,06168287 0,10821556 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,06168287 0,10813308 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06211823 0,10881334 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06211823 0,10873053 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06211823 0,10864785 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06211823 0,10856529 ! water transport GO:0006833 17 13 0,000 0,06211823 0,10848285 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06211823 0,10840055 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06211823 0,10831836 ! lipid localization GO:0010876 24 13 0,000 0,06211823 0,1082363 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06211823 0,10815437 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06211823 0,10807256 ! organelle fusion GO:0048284 28 13 0,000 0,06211823 0,10799087 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06211823 0,1079093 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06211823 0,10782786 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,06211823 0,10774655 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06211823 0,10766535 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06211823 0,10758428 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06211823 0,10750333 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06211823 0,1074225 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06211823 0,10734179 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06211823 0,1072612 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06211823 0,10718073 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06211823 0,10710039 ! NAD metabolic process GO:0019674 21 13 0,000 0,06211823 0,10702016 ! exocrine system development GO:0035272 27 13 0,000 0,06211823 0,10694006 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06211823 0,10686007 ! bone mineralization GO:0030282 15 13 0,000 0,06211823 0,10678021 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,06211823 0,10670046 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06211823 0,10662084 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06211823 0,10654133 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06211823 0,10646194 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,06211823 0,10638267 ! genitalia development GO:0048806 15 13 0,000 0,06211823 0,10630351 ! cellular pigmentation GO:0033059 24 13 0,000 0,06211823 0,10622448 ! tissue regeneration GO:0042246 21 13 0,000 0,06211823 0,10614556 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06211823 0,10606676 ! cofactor transport GO:0051181 19 13 0,000 0,06211823 0,10598807 ! NADP metabolic process GO:0006739 18 13 0,000 0,06211823 0,1059095 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06211823 0,10583105 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06211823 0,10575272 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06211823 0,1056745 ! gas transport GO:0015669 18 13 0,000 0,06211823 0,10559639 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06211823 0,1055184 ! regulation of axon extension GO:0030516 23 13 0,000 0,06211823 0,10544053 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06211823 0,10536277 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,06211823 0,10528513 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06211823 0,1052076 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06211823 0,10513018 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06211823 0,10505288 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06211823 0,10497569 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,06300944 0,1064036 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,0643457 0,10858042 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,06569153 0,11077018 ! regulation of membrane potential GO:0042391 128 85 1,000 0,06569153 0,11068903 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,06569153 0,110608 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,06673542 0,11228345 ! superoxide anion generation GO:0042554 18 14 0,000 0,06673542 0,11220137 ! neuron maturation GO:0042551 21 14 0,000 0,06673542 0,11211941 ! regulation of S phase GO:0033261 18 14 0,000 0,06673542 0,11203757 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,06673542 0,11195585 ! myotube differentiation GO:0014902 21 14 0,000 0,06673542 0,11187425 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,06673542 0,11179277 ! inositol metabolic process GO:0006020 20 14 0,000 0,06673542 0,11171141 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,06673542 0,11163016 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,06673542 0,11154904 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,06673542 0,11146803 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,06673542 0,11138714 ! gene silencing by RNA GO:0031047 20 14 0,000 0,06673542 0,11130636 ! response to cAMP GO:0051591 19 14 0,000 0,06673542 0,11122571 ! limbic system development GO:0021761 25 14 0,000 0,06673542 0,11114517 ! startle response GO:0001964 21 14 0,000 0,06673542 0,11106474 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,06673542 0,11098444 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,06673542 0,11090425 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,06673542 0,11082417 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,06673542 0,11074421 ! glycine metabolic process GO:0006544 22 14 0,000 0,06673542 0,11066437 ! pituitary gland development GO:0021983 23 14 0,000 0,06673542 0,11058464 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,06673542 0,11050502 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,06673542 0,11042552 ! regulation of heart rate GO:0002027 23 14 0,000 0,06673542 0,11034614 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,06673542 0,11026686 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,06673542 0,11018771 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,06673542 0,11010866 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,06673542 0,11002973 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,06673542 0,10995091 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,06673542 0,10987221 ! axon cargo transport GO:0008088 27 14 0,000 0,06673542 0,10979362 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,06673542 0,10971514 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,06673542 0,10963677 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,06673542 0,10955851 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,06673542 0,10948037 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06673542 0,10940233 ! mRNA splice site selection GO:0006376 26 14 0,000 0,06673542 0,10932441 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,06673542 0,1092466 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,06673542 0,1091689 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,06673542 0,10909131 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,06673542 0,10901383 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,06673542 0,10893646 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,06673542 0,1088592 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,06673542 0,10878205 ! muscle maintenance GO:0046716 19 14 0,000 0,06673542 0,10870501 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,06673542 0,10862808 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,06673542 0,10855126 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,06673542 0,10847454 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,06673542 0,10839793 ! cell killing GO:0001906 20 14 0,000 0,06673542 0,10832144 ! cilium assembly GO:0042384 20 14 0,000 0,06673542 0,10824505 ! peptide hormone secretion GO:0030072 23 14 0,000 0,06673542 0,10816876 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,06978522 0,1130324 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,0711681 0,11519116 ! regulation of T cell activation GO:0050863 128 89 1,000 0,0711681 0,11511015 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,07133015 0,11529118 ! positive regulation of cell size GO:0045793 20 15 0,000 0,07133015 0,11521022 ! metencephalon development GO:0022037 19 15 0,000 0,07133015 0,11512937 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,07133015 0,11504864 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,07133015 0,11496801 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,07133015 0,1148875 ! skin development GO:0043588 25 15 0,000 0,07133015 0,11480711 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,07133015 0,11472682 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,07133015 0,11464665 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,07133015 0,11456659 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,07133015 0,11448664 ! bile acid metabolic process GO:0008206 22 15 0,000 0,07133015 0,1144068 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,07133015 0,11432708 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,07133015 0,11424746 ! adult walking behavior GO:0007628 25 15 0,000 0,07133015 0,11416796 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,07133015 0,11408856 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,07133015 0,11400928 ! myoblast differentiation GO:0045445 27 15 0,000 0,07133015 0,11393011 ! centrosome cycle GO:0007098 16 15 0,000 0,07133015 0,11385104 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,07133015 0,11377209 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,07133015 0,11369325 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,07133015 0,11361451 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,07133015 0,11353589 ! cerebral cortex development GO:0021987 29 15 0,000 0,07133015 0,11345737 ! response to osmotic stress GO:0006970 22 15 0,000 0,07133015 0,11337896 ! vesicle coating GO:0006901 25 15 0,000 0,07133015 0,11330066 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,07133015 0,11322247 ! DNA integration GO:0015074 22 15 0,000 0,07133015 0,11314438 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,07133015 0,11306641 ! peptide secretion GO:0002790 27 15 0,000 0,07133015 0,11298854 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,07133015 0,11291077 ! regulation of vasodilation GO:0042312 24 15 0,000 0,07133015 0,11283312 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,07133015 0,11275557 ! neuron recognition GO:0008038 22 15 0,000 0,07133015 0,11267813 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,07133015 0,11260079 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,07133015 0,11252356 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,07133015 0,11244644 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,07133015 0,11236942 ! biomineral formation GO:0031214 18 15 0,000 0,07133015 0,11229251 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,07133015 0,1122157 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,07133015 0,112139 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,07133015 0,1120624 ! dopamine metabolic process GO:0042417 30 15 0,000 0,07133015 0,11198591 ! organic cation transport GO:0015695 19 15 0,000 0,07133015 0,11190952 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,07133015 0,11183323 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,07133015 0,11175705 ! peptide hormone processing GO:0016486 19 15 0,000 0,07133015 0,11168098 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,07133015 0,111605 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,07255995 0,11345199 ! response to virus GO:0009615 122 91 1,000 0,07396063 0,11556349 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,07537004 0,11768574 ! cell fate commitment GO:0045165 141 92 1,000 0,07537004 0,1176059 ! sulfur metabolic process GO:0006790 118 92 1,000 0,07537004 0,11752616 ! protein secretion GO:0009306 27 16 0,000 0,07590253 0,11827629 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,07590253 0,11819621 ! hormone secretion GO:0046879 25 16 0,000 0,07590253 0,11811624 ! bone remodeling GO:0046849 24 16 0,000 0,07590253 0,11803638 ! endothelial cell migration GO:0043542 22 16 0,000 0,07590253 0,11795663 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07590253 0,11787698 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,07590253 0,11779744 ! glial cell development GO:0021782 24 16 0,000 0,07590253 0,11771801 ! patterning of blood vessels GO:0001569 24 16 0,000 0,07590253 0,11763869 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,07590253 0,11755947 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,07590253 0,11748036 ! protein polyubiquitination GO:0000209 26 16 0,000 0,07590253 0,11740135 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,07590253 0,11732245 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,07590253 0,11724366 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,07590253 0,11716497 ! fructose metabolic process GO:0006000 20 16 0,000 0,07590253 0,11708639 ! regulation of protein binding GO:0043393 27 16 0,000 0,07590253 0,11700791 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,07590253 0,11692954 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,07590253 0,11685128 ! protein export from nucleus GO:0006611 24 16 0,000 0,07590253 0,11677312 ! negative regulation of immune response GO:0050777 28 16 0,000 0,07590253 0,11669506 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,07590253 0,11661711 ! DNA replication initiation GO:0006270 25 16 0,000 0,07590253 0,11653926 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,07590253 0,11646151 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,07590253 0,11638387 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,07590253 0,11630634 ! diencephalon development GO:0021536 25 16 0,000 0,07590253 0,1162289 ! oogenesis GO:0048477 23 16 0,000 0,07590253 0,11615157 ! neural crest cell migration GO:0001755 24 16 0,000 0,07590253 0,11607434 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,07590253 0,11599722 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,07590253 0,11592019 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,07590253 0,11584327 ! steroid catabolic process GO:0006706 22 16 0,000 0,07590253 0,11576645 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,07590253 0,11568973 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,07590253 0,11561312 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,07590253 0,1155366 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,07590253 0,11546019 ! sperm-egg recognition GO:0035036 16 16 0,000 0,07590253 0,11538388 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,07590253 0,11530767 ! nerve development GO:0021675 18 16 0,000 0,07590253 0,11523156 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,07590253 0,11515555 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,07590253 0,11507964 ! negative regulation of translation GO:0017148 22 16 0,000 0,07590253 0,11500383 ! regulation of binding GO:0051098 151 95 1,000 0,07964943 0,12060151 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,08045264 0,12173755 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,08045264 0,12165752 ! negative regulation of defense response GO:0031348 19 17 0,000 0,08045264 0,12157758 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,08045264 0,12149776 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,08045264 0,12141803 ! glycerol metabolic process GO:0006071 20 17 0,000 0,08045264 0,12133842 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,08045264 0,1212589 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,08045264 0,12117949 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,08045264 0,12110019 ! signal complex assembly GO:0007172 29 17 0,000 0,08045264 0,12102098 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,08045264 0,12094188 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,08045264 0,12086289 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,08045264 0,120784 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,08045264 0,12070521 ! memory GO:0007613 25 17 0,000 0,08045264 0,12062652 ! keratinization GO:0031424 17 17 0,000 0,08045264 0,12054794 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,08045264 0,12046946 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,08045264 0,12039108 ! retinoid metabolic process GO:0001523 22 17 0,000 0,08045264 0,1203128 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,08045264 0,12023462 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,08045264 0,12015655 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,08045264 0,12007857 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,08045264 0,1200007 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,08045264 0,11992293 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,08045264 0,11984526 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,08045264 0,11976769 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,08045264 0,11969022 ! membrane budding GO:0006900 29 17 0,000 0,08045264 0,11961285 ! heme metabolic process GO:0042168 27 17 0,000 0,08045264 0,11953558 ! actin filament bundle formation GO:0051017 26 17 0,000 0,08045264 0,11945841 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,08045264 0,11938134 ! body fluid secretion GO:0007589 27 17 0,000 0,08045264 0,11930437 ! stem cell differentiation GO:0048863 36 17 0,000 0,08045264 0,1192275 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,08045264 0,11915073 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,08045264 0,11907406 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,08045264 0,11899748 ! sensory perception of pain GO:0019233 23 17 0,000 0,08045264 0,118921 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,08045264 0,11884463 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,08045264 0,11876835 ! synaptogenesis GO:0007416 24 17 0,000 0,08045264 0,11869216 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,08045264 0,11861608 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,08045264 0,11854009 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,08045264 0,1184642 ! cell-cell junction organization GO:0045216 25 17 0,000 0,08045264 0,11838841 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,08045264 0,11831271 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,08045264 0,11823711 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,08045264 0,11816161 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,08045264 0,11808621 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,08045264 0,11801089 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,08109256 0,11887374 ! in utero embryonic development GO:0001701 147 96 1,000 0,08109256 0,11879802 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,08109256 0,1187224 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,08498062 0,12433551 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,08498062 0,12425647 ! positive regulation of translation GO:0045727 28 18 0,000 0,08498062 0,12417753 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,08498062 0,12409868 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,08498062 0,12401994 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,08498062 0,1239413 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,08498062 0,12386275 ! cAMP metabolic process GO:0046058 33 18 0,000 0,08498062 0,12378431 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,08498062 0,12370596 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,08498062 0,12362772 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,08498062 0,12354957 ! axis specification GO:0009798 26 18 0,000 0,08498062 0,12347153 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,08498062 0,12339358 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,08498062 0,12331573 ! pancreas development GO:0031016 26 18 0,000 0,08498062 0,12323797 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,08498062 0,12316032 ! glutamine metabolic process GO:0006541 23 18 0,000 0,08498062 0,12308276 ! response to retinoic acid GO:0032526 25 18 0,000 0,08498062 0,1230053 ! pigmentation during development GO:0048066 31 18 0,000 0,08498062 0,12292794 ! central nervous system neuron development GO:0021954 30 18 0,000 0,08498062 0,12285068 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,08498062 0,12277351 ! fucose metabolic process GO:0006004 26 18 0,000 0,08498062 0,12269644 ! response to fungus GO:0009620 19 18 0,000 0,08498062 0,12261946 ! peptide cross-linking GO:0018149 31 18 0,000 0,08498062 0,12254259 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,08498062 0,1224658 ! heart process GO:0003015 27 18 0,000 0,08498062 0,12238912 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,08498062 0,12231253 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,08498062 0,12223604 ! visual learning GO:0008542 35 18 0,000 0,08498062 0,12215964 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,08498062 0,12208334 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,08498062 0,12200713 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,08498062 0,12193102 ! vitamin transport GO:0051180 24 18 0,000 0,08498062 0,121855 ! hormone transport GO:0009914 27 18 0,000 0,08498062 0,12177908 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,08498062 0,12170325 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,08498062 0,12162752 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,08498062 0,12155188 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,08498062 0,12147634 ! cell-cell recognition GO:0009988 20 18 0,000 0,08498062 0,12140088 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,08498062 0,12132553 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,08498062 0,12125026 ! regulation of glucose import GO:0046324 21 18 0,000 0,08498062 0,12117509 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,08498062 0,12110002 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,08498062 0,12102503 ! extracellular structure organization GO:0043062 156 99 1,000 0,08547038 0,12164721 ! protein import GO:0017038 156 99 1,000 0,08547038 0,12157198 ! regulation of translation GO:0006417 151 100 1,000 0,08694542 0,12359362 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,08694542 0,12351728 ! protein localization in organelle GO:0033365 161 100 1,000 0,08694542 0,12344104 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,08948656 0,12697044 ! positive regulation of ossification GO:0045778 30 19 0,000 0,08948656 0,12689216 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,08948656 0,12681397 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,08948656 0,12673589 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,08948656 0,12665789 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,08948656 0,12658 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,08948656 0,1265022 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,08948656 0,12642449 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,08948656 0,12634689 ! regeneration GO:0031099 32 19 0,000 0,08948656 0,12626937 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,08948656 0,12619195 ! response to alkaloid GO:0043279 32 19 0,000 0,08948656 0,12611463 ! sensory perception of taste GO:0050909 23 19 0,000 0,08948656 0,1260374 ! smooth muscle contraction GO:0006939 36 19 0,000 0,08948656 0,12596027 ! peroxisome organization GO:0007031 29 19 0,000 0,08948656 0,12588323 ! digestive system process GO:0022600 30 19 0,000 0,08948656 0,12580628 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,08948656 0,12572943 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,08948656 0,12565267 ! response to vitamin A GO:0033189 26 19 0,000 0,08948656 0,12557601 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,08948656 0,12549944 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,08948656 0,12542296 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,08948656 0,12534658 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,08948656 0,12527028 ! sex determination GO:0007530 29 19 0,000 0,08948656 0,12519409 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,08948656 0,12511798 ! plasma membrane fusion GO:0045026 23 19 0,000 0,08948656 0,12504197 ! cytolysis GO:0019835 20 19 0,000 0,08948656 0,12496605 ! renal system process GO:0003014 35 19 0,000 0,08948656 0,12489022 ! vasodilation GO:0042311 33 19 0,000 0,08948656 0,12481448 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,08948656 0,12473883 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,08948656 0,12466328 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,08948656 0,12458782 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,08948656 0,12451245 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,08948656 0,12443717 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,08948656 0,12436198 ! sarcomere organization GO:0045214 23 19 0,000 0,08948656 0,12428688 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,08948656 0,12421188 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,08948656 0,12413696 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,08948656 0,12406213 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,08948656 0,1239874 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,08948656 0,12391275 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,08948656 0,12383819 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,08948656 0,12376373 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,08948656 0,12368935 ! protein stabilization GO:0050821 26 19 0,000 0,08948656 0,12361506 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,09397056 0,12973126 ! iron ion transport GO:0006826 37 20 0,000 0,09397056 0,12965344 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,09397056 0,12957571 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,09397056 0,12949807 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,09397056 0,12942053 ! response to vitamin GO:0033273 29 20 0,000 0,09397056 0,12934308 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,09397056 0,12926572 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,09397056 0,12918846 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,09397056 0,12911128 ! spinal cord development GO:0021510 31 20 0,000 0,09397056 0,1290342 ! response to ethanol GO:0045471 37 20 0,000 0,09397056 0,12895721 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,09397056 0,12888031 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,09397056 0,12880351 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,09397056 0,12872679 ! chromosome condensation GO:0030261 31 20 0,000 0,09397056 0,12865017 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,09397056 0,12857364 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,09397056 0,1284972 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,09397056 0,12842085 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,09397056 0,12834459 ! pallium development GO:0021543 38 20 0,000 0,09397056 0,12826842 ! DNA modification GO:0006304 28 20 0,000 0,09397056 0,12819234 ! collagen fibril organization GO:0030199 45 20 0,000 0,09397056 0,12811635 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,09397056 0,12804045 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,09397056 0,12796465 ! collagen catabolic process GO:0030574 25 20 0,000 0,09397056 0,12788893 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,09397056 0,1278133 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,09397056 0,12773776 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,09397056 0,12766231 ! alditol metabolic process GO:0019400 24 20 0,000 0,09397056 0,12758695 ! actin filament-based movement GO:0030048 34 20 0,000 0,09397056 0,12751167 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,09843274 0,13348779 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,09843274 0,13340913 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,09843274 0,13333056 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,09843274 0,13325209 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,09843274 0,1331737 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,09843274 0,13309541 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,09843274 0,13301721 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,09843274 0,1329391 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,09843274 0,13286109 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,09843274 0,13278316 ! vesicle docking GO:0048278 27 21 0,000 0,09843274 0,13270533 ! phototransduction GO:0007602 25 21 0,000 0,09843274 0,13262759 ! dendrite development GO:0016358 35 21 0,000 0,09843274 0,13254994 ! visual behavior GO:0007632 39 21 0,000 0,09843274 0,13247238 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,09843274 0,13239491 ! ovarian follicle development GO:0001541 30 21 0,000 0,09843274 0,13231753 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,09843274 0,13224024 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,09843274 0,13216304 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,09843274 0,13208593 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,09843274 0,13200892 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,09843274 0,13193199 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,09843274 0,13185515 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,09843274 0,1317784 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,09843274 0,13170174 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,09843274 0,13162517 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,09843274 0,13154869 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,09843274 0,1314723 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,09843274 0,13139599 ! fatty acid transport GO:0015908 30 21 0,000 0,09843274 0,13131978 ! immunoglobulin production GO:0002377 33 21 0,000 0,09843274 0,13124365 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,09843274 0,13116761 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,09843274 0,13109166 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,09843274 0,13101579 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,09843274 0,13094002 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,09843274 0,13086433 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,09843274 0,13078873 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,09843274 0,13071322 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,09843274 0,13063779 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,09843274 0,13056245 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,09843274 0,1304872 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,09843274 0,13041203 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,09843274 0,13033696 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,09843274 0,13026196 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,09843274 0,13018706 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,10287319 0,1359818 ! viral genome replication GO:0019079 29 22 0,000 0,10287319 0,1359037 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,10287319 0,13582568 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,10287319 0,13574776 ! leukocyte adhesion GO:0007159 38 22 0,000 0,10287319 0,13566992 ! molting cycle process GO:0022404 40 22 0,000 0,10287319 0,13559217 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,10287319 0,13551451 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,10287319 0,13543694 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,10287319 0,13535946 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,10287319 0,13528207 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,10287319 0,13520477 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,10287319 0,13512755 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,10287319 0,13505042 ! lysosome organization GO:0007040 37 22 0,000 0,10287319 0,13497338 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,10287319 0,13489643 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,10287319 0,13481957 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,10287319 0,13474279 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,10287319 0,1346661 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,10287319 0,1345895 ! membrane depolarization GO:0051899 35 22 0,000 0,10287319 0,13451298 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,10287319 0,13443656 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,10287319 0,13436022 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,10287319 0,13428396 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,10287319 0,13420779 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,10287319 0,13413171 ! blastocyst development GO:0001824 37 22 0,000 0,10287319 0,13405572 ! neural tube closure GO:0001843 33 22 0,000 0,10287319 0,13397981 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,10287319 0,13390398 ! neuron fate commitment GO:0048663 32 23 0,000 0,10729203 0,13957673 ! embryonic pattern specification GO:0009880 31 23 0,000 0,10729203 0,13949783 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,10729203 0,13941902 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,10729203 0,1393403 ! vesicle targeting GO:0006903 32 23 0,000 0,10729203 0,13926166 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,10729203 0,13918312 ! osteoblast differentiation GO:0001649 40 23 0,000 0,10729203 0,13910466 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,10729203 0,13902629 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,10729203 0,13894801 ! interaction with host GO:0051701 37 23 0,000 0,10729203 0,13886982 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,10729203 0,13879171 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,10729203 0,1387137 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,10729203 0,13863577 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,10729203 0,13855793 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,10729203 0,13848017 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,10729203 0,1384025 ! cell fate determination GO:0001709 45 23 0,000 0,10729203 0,13832492 ! pentose metabolic process GO:0019321 31 23 0,000 0,10729203 0,13824743 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,10729203 0,13817003 ! spermatid development GO:0007286 33 23 0,000 0,10729203 0,13809271 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,10729203 0,13801547 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,10729203 0,13793833 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,10729203 0,13786127 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,10729203 0,13778429 ! telomere organization GO:0032200 32 23 0,000 0,10729203 0,1377074 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,10729203 0,1376306 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,10729203 0,13755388 ! regulation of amine transport GO:0051952 38 23 0,000 0,10729203 0,13747725 ! liver development GO:0001889 40 23 0,000 0,10729203 0,1374007 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,11168935 0,14295243 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,11168935 0,14287292 ! initiation of viral infection GO:0019059 42 24 0,000 0,11168935 0,1427935 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,11168935 0,14271417 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,11168935 0,14263493 ! superoxide metabolic process GO:0006801 32 24 0,000 0,11168935 0,14255578 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,11168935 0,14247671 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,11168935 0,14239773 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,11168935 0,14231884 ! sperm motility GO:0030317 27 24 0,000 0,11168935 0,14224004 ! vacuole organization GO:0007033 39 24 0,000 0,11168935 0,14216132 ! receptor metabolic process GO:0043112 37 24 0,000 0,11168935 0,14208269 ! neural crest cell development GO:0014032 39 24 0,000 0,11168935 0,14200415 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,11168935 0,1419257 ! primary neural tube formation GO:0014020 35 24 0,000 0,11168935 0,14184733 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,11168935 0,14176905 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,11168935 0,14169085 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,11168935 0,14161274 ! glutathione metabolic process GO:0006749 29 24 0,000 0,11168935 0,14153472 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,11168935 0,14145678 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,11606527 0,14691806 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,11606527 0,14683725 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,11606527 0,14675652 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,11606527 0,14667589 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,11606527 0,14659534 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,11606527 0,14651488 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,11606527 0,14643451 ! peptide transport GO:0015833 43 25 0,000 0,11606527 0,14635423 ! male gonad development GO:0008584 33 25 0,000 0,11606527 0,14627404 ! iron ion homeostasis GO:0055072 39 25 0,000 0,11606527 0,14619393 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,11606527 0,14611391 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,11606527 0,14603398 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,11606527 0,14595414 ! phospholipid transport GO:0015914 35 25 0,000 0,11606527 0,14587438 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,11606527 0,14579471 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,11606527 0,14571513 ! detection of light stimulus GO:0009583 30 25 0,000 0,11606527 0,14563563 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,11606527 0,14555622 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,11606527 0,1454769 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,12041988 0,15085278 ! translational initiation GO:0006413 43 26 0,000 0,12041988 0,15077067 ! circadian rhythm GO:0007623 42 26 0,000 0,12041988 0,15068864 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,12041988 0,1506067 ! post-embryonic development GO:0009791 42 26 0,000 0,12041988 0,15052484 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,12041988 0,15044308 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,12041988 0,15036141 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,12041988 0,15027982 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,12041988 0,15019833 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,12041988 0,15011692 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,12041988 0,1500356 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,12041988 0,14995437 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,12041988 0,14987322 ! regulation of coagulation GO:0050818 39 26 0,000 0,12041988 0,14979216 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,12475328 0,15509867 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,12475328 0,15501488 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,12475328 0,15493118 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,12475328 0,15484757 ! membrane docking GO:0022406 39 27 0,000 0,12475328 0,15476405 ! catechol metabolic process GO:0009712 43 27 0,000 0,12475328 0,15468061 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,12475328 0,15459727 ! acute-phase response GO:0006953 42 27 0,000 0,12475328 0,15451402 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,12475328 0,15443086 ! myofibril assembly GO:0030239 36 27 0,000 0,12475328 0,15434779 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,12475328 0,15426481 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,12475328 0,15418191 ! natural killer cell activation GO:0030101 35 27 0,000 0,12475328 0,15409911 ! lipid oxidation GO:0034440 38 27 0,000 0,12475328 0,15401639 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,12475328 0,15393377 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,12475328 0,15385123 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,12475328 0,15376878 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,12475328 0,15368642 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,12906558 0,15891372 ! phenol metabolic process GO:0018958 44 28 0,000 0,12906558 0,1588287 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,12906558 0,15874376 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,12906558 0,15865892 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,12906558 0,15857416 ! cell junction assembly GO:0034329 56 28 0,000 0,12906558 0,1584895 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,12906558 0,15840493 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,12906558 0,15832044 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,12906558 0,15823605 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,12906558 0,15815175 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,12906558 0,15806754 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,12906558 0,15798341 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,12906558 0,15789938 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,12906558 0,15781544 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,12906558 0,15773158 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,12906558 0,15764781 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,12906558 0,15756414 ! mesoderm formation GO:0001707 46 28 0,000 0,12906558 0,15748055 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,12906558 0,15739705 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,12906558 0,15731364 ! BMP signaling pathway GO:0030509 40 28 0,000 0,12906558 0,15723031 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,12906558 0,15714708 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,12906558 0,15706393 ! neural tube formation GO:0001841 41 28 0,000 0,12906558 0,15698087 ! placenta development GO:0001890 37 28 0,000 0,12906558 0,1568979 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,13335688 0,16202896 ! regulation of innate immune response GO:0045088 38 29 0,000 0,13335688 0,16194341 ! ovulation cycle process GO:0022602 41 29 0,000 0,13335688 0,16185796 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,13335688 0,16177259 ! protein targeting to membrane GO:0006612 53 29 0,000 0,13335688 0,16168731 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,13335688 0,16160212 ! mismatch repair GO:0006298 34 29 0,000 0,13335688 0,16151702 ! muscle cell development GO:0055001 38 29 0,000 0,13335688 0,16143201 ! formation of primary germ layer GO:0001704 48 29 0,000 0,13335688 0,16134709 ! telencephalon development GO:0021537 52 29 0,000 0,13335688 0,16126226 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,13335688 0,16117752 ! eye morphogenesis GO:0048592 51 29 0,000 0,13335688 0,16109287 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,13335688 0,16100831 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,13762728 0,16607699 ! collagen metabolic process GO:0032963 40 30 0,000 0,13762728 0,1659899 ! organic anion transport GO:0015711 51 30 0,000 0,13762728 0,16590291 ! cholesterol transport GO:0030301 46 30 0,000 0,13762728 0,165816 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,13762728 0,16572919 ! spliceosome assembly GO:0000245 49 30 0,000 0,13762728 0,16564246 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,13762728 0,16555583 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,13762728 0,16546929 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,13762728 0,16538284 ! ceramide metabolic process GO:0006672 43 30 0,000 0,13762728 0,16529647 ! ovulation cycle GO:0042698 43 30 0,000 0,13762728 0,1652102 ! hindbrain development GO:0030902 45 30 0,000 0,13762728 0,16512402 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,13762728 0,16503793 ! adult locomotory behavior GO:0008344 47 30 0,000 0,13762728 0,16495193 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,13762728 0,16486601 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,13762728 0,16478019 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,13762728 0,16469446 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,13762728 0,16460881 ! negative regulation of secretion GO:0051048 49 31 0,000 0,14187688 0,16960334 ! glial cell differentiation GO:0010001 55 31 0,000 0,14187688 0,16951524 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,14187688 0,16942722 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,14187688 0,1693393 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,14187688 0,16925147 ! odontogenesis GO:0042476 50 31 0,000 0,14187688 0,16916373 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,14187688 0,16907608 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,14187688 0,16898852 ! metanephros development GO:0001656 58 31 0,000 0,14187688 0,16890105 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,14187688 0,16881367 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,14187688 0,16872639 ! cell fate specification GO:0001708 37 31 0,000 0,14187688 0,16863919 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,14187688 0,16855208 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,14187688 0,16846507 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,14610579 0,17339696 ! meiosis I GO:0007127 52 32 0,000 0,14610579 0,17330753 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,14610579 0,1732182 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,14610579 0,17312896 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,14610579 0,17303981 GO:0006639|acylglycerol metabolic process, ! regulation of protein stability GO:0031647 48 32 0,000 0,14610579 0,17295075 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,14610579 0,17286178 ! cytokine production GO:0001816 44 32 0,000 0,14610579 0,17277291 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,14610579 0,17268413 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,14610579 0,17259543 ! vesicle localization GO:0051648 47 32 0,000 0,14610579 0,17250683 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,15031409 0,17738451 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,15031409 0,17729354 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,15031409 0,17720267 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,15031409 0,17711189 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,15031409 0,1770212 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,15031409 0,17693061 ! sister chromatid segregation GO:0000819 46 33 0,000 0,15031409 0,17684011 ! actomyosin structure organization GO:0031032 43 33 0,000 0,15031409 0,1767497 ! cell junction organization GO:0034330 63 33 0,000 0,15031409 0,17665938 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,15031409 0,17656916 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,15031409 0,17647902 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,15031409 0,17638898 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,15031409 0,17629903 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,15031409 0,17620918 ! female gonad development GO:0008585 49 33 0,000 0,15031409 0,17611941 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,15031409 0,17602974 ! positive regulation of cell development GO:0010720 54 33 0,000 0,15031409 0,17594016 ! lipid homeostasis GO:0055088 55 33 0,000 0,15031409 0,17585067 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,15031409 0,17576126 ! regulation of proteolysis GO:0030162 50 33 0,000 0,15031409 0,17567196 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,15031409 0,17558274 ! cytokinesis GO:0000910 52 33 0,000 0,15031409 0,17549361 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,15031409 0,17540457 ! mRNA catabolic process GO:0006402 48 34 0,000 0,15450189 0,18019998 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,15450189 0,18010864 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,15450189 0,1800174 ! feeding behavior GO:0007631 45 34 0,000 0,15450189 0,17992626 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,15450189 0,1798352 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,15450189 0,17974424 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,15450189 0,17965337 ! neuron migration GO:0001764 46 34 0,000 0,15450189 0,17956259 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,15450189 0,1794719 ! female gamete generation GO:0007292 43 34 0,000 0,15450189 0,1793813 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,15450189 0,1792908 ! polyol metabolic process GO:0019751 44 34 0,000 0,15450189 0,17920038 ! aerobic respiration GO:0009060 47 34 0,000 0,15450189 0,17911006 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,15450189 0,17901983 ! embryonic organ development GO:0048568 45 34 0,000 0,15450189 0,17892969 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,15450189 0,17883964 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,1586693 0,18357112 ! Notch signaling pathway GO:0007219 56 35 0,000 0,1586693 0,18347882 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,1586693 0,18338662 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,1586693 0,18329452 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,1586693 0,1832025 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,1586693 0,18311058 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,1586693 0,18301875 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,1586693 0,18292701 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,1586693 0,18283536 ! glycogen metabolic process GO:0005977 48 35 0,000 0,1586693 0,18274381 ! pigment metabolic process GO:0042440 61 35 0,000 0,1586693 0,18265234 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,1628164 0,18733252 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,1628164 0,18723886 ! negative regulation of binding GO:0051100 58 36 0,000 0,1628164 0,18714528 ! organic ether metabolic process GO:0018904 46 36 0,000 0,1628164 0,1870518 ! neural tube development GO:0021915 50 36 0,000 0,1628164 0,18695842 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,1628164 0,18686512 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,1628164 0,18677193 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,1628164 0,18667882 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,1628164 0,1865858 ! glucan metabolic process GO:0044042 49 36 0,000 0,1628164 0,18649288 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,16694329 0,19112472 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,16694329 0,19102963 ! learning GO:0007612 67 37 0,000 0,16694329 0,19093464 ! ion transmembrane transport GO:0034220 56 37 0,000 0,16694329 0,19083974 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,16694329 0,19074494 ! regulation of protein secretion GO:0050708 51 37 0,000 0,16694329 0,19065023 ! amino acid activation GO:0043038 52 37 0,000 0,16694329 0,19055562 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,16694329 0,19046109 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,17105008 0,19504966 ! gliogenesis GO:0042063 71 38 0,000 0,17105008 0,19495301 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,17105008 0,19485645 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,17105008 0,19475999 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,17105008 0,19466362 ! phagocytosis GO:0006909 60 38 0,000 0,17105008 0,19456735 ! pigmentation GO:0043473 74 38 0,000 0,17105008 0,19447117 ! maintenance of location in cell GO:0051651 69 38 0,000 0,17105008 0,19437509 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,17513685 0,19892087 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,17513685 0,19882268 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,17513685 0,1987246 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,17513685 0,1986266 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,17513685 0,19852871 ! male sex differentiation GO:0046661 53 39 0,000 0,17513685 0,19843091 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,17513685 0,19833321 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,17513685 0,19823561 ! JNK cascade GO:0007254 54 39 0,000 0,17513685 0,1981381 ! developmental growth GO:0048589 62 39 0,000 0,17513685 0,19804069 ! cell growth GO:0016049 61 39 0,000 0,17513685 0,19794337 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,17920371 0,20244034 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,17920371 0,20234096 ! regulation of tube size GO:0035150 60 40 0,000 0,17920371 0,20224167 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,17920371 0,20214249 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,17920371 0,2020434 ! peptide metabolic process GO:0006518 56 40 0,000 0,17920371 0,20194441 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,17920371 0,20184551 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,17920371 0,20174671 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,17920371 0,20164801 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,18325075 0,20610109 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,18325075 0,20600035 ! glucose transport GO:0015758 52 41 0,000 0,18325075 0,20589972 ! endosome transport GO:0016197 71 41 0,000 0,18325075 0,20579918 ! striated muscle contraction GO:0006941 62 41 0,000 0,18325075 0,20569874 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,18325075 0,2055984 ! biopolymer methylation GO:0043414 62 41 0,000 0,18325075 0,20549816 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,18325075 0,20539801 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,18727807 0,20980982 ! cellular component disassembly GO:0022411 64 42 0,000 0,18727807 0,20970767 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,18727807 0,20960562 ! hexose transport GO:0008645 54 42 0,000 0,18727807 0,20950367 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,18727807 0,20940182 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,18727807 0,20930007 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,18727807 0,20919842 ! excretion GO:0007588 63 42 0,000 0,18727807 0,20909687 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,18727807 0,20899542 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,18727807 0,20889406 ! leukocyte migration GO:0050900 60 43 0,000 0,19128576 0,2132609 ! neuromuscular process GO:0050905 79 43 0,000 0,19128576 0,21315758 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,19128576 0,21305435 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,19128576 0,21295123 ! vesicle organization GO:0016050 79 43 0,000 0,19128576 0,2128482 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,19128576 0,21274528 ! methylation GO:0032259 64 43 0,000 0,19128576 0,21264245 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,19527391 0,21697101 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,19527391 0,21686624 ! glycolysis GO:0006096 53 44 0,000 0,19527391 0,21676158 ! regulation of ion transport GO:0043269 57 44 0,000 0,19527391 0,21665702 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,19527391 0,21655255 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,19527391 0,21644819 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,19527391 0,21634393 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,19527391 0,21623977 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,19527391 0,2161357 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,19527391 0,21603174 ! RNA catabolic process GO:0006401 64 45 0,000 0,19924262 0,22031636 ! positive regulation of defense response GO:0031349 59 45 0,000 0,19924262 0,22021049 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,19924262 0,22010472 ! cell recognition GO:0008037 58 45 0,000 0,19924262 0,21999906 ! cell maturation GO:0048469 60 45 0,000 0,19924262 0,21989349 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,20319199 0,22414464 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,20319199 0,22403719 ! cell redox homeostasis GO:0045454 63 46 0,000 0,20319199 0,22392984 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,20319199 0,2238226 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,20319199 0,22371545 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,20712211 0,22793342 ! viral infectious cycle GO:0019058 71 47 0,000 0,20712211 0,22782441 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,20712211 0,22771551 ! endocrine system development GO:0035270 83 47 0,000 0,20712211 0,22760671 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,20712211 0,22749802 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,20712211 0,22738943 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,20712211 0,22728094 ! chloride transport GO:0006821 67 48 0,000 0,21103306 0,23146211 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,21103306 0,23135178 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,21103306 0,23124156 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,21103306 0,23113145 ! gastrulation GO:0007369 73 48 0,000 0,21103306 0,23102144 ! heart morphogenesis GO:0003007 65 48 0,000 0,21103306 0,23091153 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,21103306 0,23080173 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,21103306 0,23069204 ! regulation of endocytosis GO:0030100 63 48 0,000 0,21103306 0,23058244 ! nuclear export GO:0051168 69 48 0,000 0,21103306 0,23047296 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,21103306 0,23036357 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,21492495 0,23450066 ! sensory perception of smell GO:0007608 61 49 0,000 0,21492495 0,23438947 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,21492495 0,23427838 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,21492495 0,2341674 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,21492495 0,23405653 ! germ cell development GO:0007281 68 49 0,000 0,21492495 0,23394576 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,21492495 0,23383509 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,21492495 0,23372453 ! cartilage development GO:0051216 70 49 0,000 0,21492495 0,23361408 ! maintenance of location GO:0051235 84 49 0,000 0,21492495 0,23350372 ! regulation of actin filament length GO:0030832 72 50 0,000 0,21879786 0,23759919 ! membrane fusion GO:0006944 80 50 0,000 0,21879786 0,23748706 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,21879786 0,23737504 ! proton transport GO:0015992 75 50 0,000 0,21879786 0,23726312 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,21879786 0,23715131 ! positive regulation of secretion GO:0051047 71 51 0,000 0,22265189 0,24121495 ! hydrogen transport GO:0006818 77 51 0,000 0,22265189 0,24110138 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,22265189 0,24098792 ! adult behavior GO:0030534 80 51 0,000 0,22265189 0,24087457 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,22265189 0,24076133 ! transition metal ion transport GO:0000041 74 52 0,000 0,22648712 0,24479341 ! regulation of cellular component size GO:0032535 74 52 0,000 0,22648712 0,24467843 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,22648712 0,24456356 ! establishment of organelle localization GO:0051656 85 52 0,000 0,22648712 0,24444879 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,23030365 0,2484514 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,23030365 0,24833492 ! kidney development GO:0001822 90 53 0,000 0,23030365 0,24821855 ! single fertilization GO:0007338 59 53 0,000 0,23030365 0,24810229 ! amino acid transport GO:0006865 84 54 0,000 0,23410156 0,25207566 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,23410156 0,2519577 ! regulation of mitosis GO:0007088 84 54 0,000 0,23410156 0,25183985 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,23410156 0,25172211 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,23410156 0,25160449 ! DNA catabolic process GO:0006308 67 54 0,000 0,23410156 0,25148697 ! detection of external stimulus GO:0009581 66 54 0,000 0,23410156 0,25136956 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,23410156 0,25125226 ! exocytosis GO:0006887 74 55 0,000 0,23788096 0,25518946 ! mesoderm development GO:0007498 76 55 0,000 0,23788096 0,25507049 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,23788096 0,25495163 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,23788096 0,25483288 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,24164192 0,25874135 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,24164192 0,25862094 ! carbohydrate transport GO:0008643 74 57 0,000 0,24538453 0,26250438 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,24538453 0,26238234 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,24538453 0,26226042 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,24538453 0,26213861 ! camera-type eye development GO:0043010 88 57 0,000 0,24538453 0,26201691 ! secondary metabolic process GO:0019748 84 57 0,000 0,24538453 0,26189532 ! developmental maturation GO:0021700 75 57 0,000 0,24538453 0,26177385 ! gonad development GO:0008406 79 57 0,000 0,24538453 0,26165249 ! viral reproductive process GO:0022415 87 58 0,000 0,24910889 0,26550067 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,24910889 0,2653777 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,24910889 0,26525484 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,25281508 0,26907667 ! actin filament organization GO:0007015 95 59 0,000 0,25281508 0,26895221 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,25281508 0,26882787 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,25281508 0,26870364 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,25650319 0,27249761 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,25650319 0,2723718 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,25650319 0,27224611 ! regulation of heart contraction GO:0008016 91 60 0,000 0,25650319 0,27212054 ! fertilization GO:0009566 68 60 0,000 0,25650319 0,27199508 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,2601733 0,27575972 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,2601733 0,2756327 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,2601733 0,2755058 ! urogenital system development GO:0001655 101 61 0,000 0,2601733 0,27537901 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,2601733 0,27525234 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,2601733 0,27512579 ! extracellular matrix organization GO:0030198 103 61 0,000 0,2601733 0,27499935 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,2601733 0,27487303 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,2601733 0,27474683 ! amine catabolic process GO:0009310 90 62 0,000 0,26382551 0,27847575 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,26382551 0,27834801 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,26382551 0,27822039 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,26382551 0,27809288 ! organelle localization GO:0051640 96 62 0,000 0,26382551 0,27796549 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,26745989 0,28166564 ! viral reproduction GO:0016032 92 63 0,000 0,26745989 0,28153673 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,27107654 0,2852132 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,27107654 0,28508279 ! hexose catabolic process GO:0019320 82 64 0,000 0,27107654 0,28495249 ! reproductive structure development GO:0048608 90 65 0,000 0,27467555 0,28860382 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,27467555 0,28847203 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,27467555 0,28834037 ! defense response to bacterium GO:0042742 73 65 0,000 0,27467555 0,28820883 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,27467555 0,28807741 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,27467555 0,28794611 ! activation of immune response GO:0002253 83 65 0,000 0,27467555 0,28781492 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,27825698 0,29143491 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,27825698 0,29130226 ! antigen processing and presentation GO:0019882 96 66 0,000 0,27825698 0,29116973 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,27825698 0,29103732 ! regulation of immune effector process GO:0002697 101 66 0,000 0,27825698 0,29090503 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,28182094 0,29449712 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,28182094 0,29436338 ! acute inflammatory response GO:0002526 92 68 0,000 0,28536751 0,29793248 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,28536751 0,29779731 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,28536751 0,29766225 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,28536751 0,29752732 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,28536751 0,29739251 ! rhythmic process GO:0048511 105 68 0,000 0,28536751 0,29725782 ! inorganic anion transport GO:0015698 93 68 0,000 0,28536751 0,29712325 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,28889676 0,30066178 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,28889676 0,3005258 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,29240878 0,30404168 ! humoral immune response GO:0006959 86 70 0,000 0,29240878 0,30390429 ! eye development GO:0001654 111 70 0,000 0,29240878 0,30376703 ! amine transport GO:0015837 101 70 0,000 0,29240878 0,30362989 ! muscle cell differentiation GO:0042692 104 71 0,000 0,29590366 0,30712023 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,29590366 0,3069817 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,29590366 0,30684329 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,29590366 0,30670501 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,29590366 0,30656686 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,29938148 0,31003035 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,29938148 0,30989082 ! regulation of blood pressure GO:0008217 107 73 0,000 0,30284232 0,31333213 ! tube morphogenesis GO:0035239 118 73 0,000 0,30284232 0,31319125 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,30284232 0,31305049 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,30284232 0,31290985 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,30628626 0,31632618 ! digestion GO:0007586 97 74 0,000 0,30628626 0,3161842 ! blood coagulation GO:0007596 116 75 0,000 0,30971338 0,31957864 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,30971338 0,31943533 ! regulation of ligase activity GO:0051340 114 75 0,000 0,30971338 0,31929215 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,30971338 0,31914909 ! amine biosynthetic process GO:0009309 97 76 0,000 0,31312377 0,32251889 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,31651751 0,32586852 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,31651751 0,32572271 ! sex differentiation GO:0007548 105 77 0,000 0,31651751 0,32557704 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,31651751 0,3254315 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,31651751 0,32528609 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,31651751 0,32514081 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,31989467 0,32846328 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,31989467 0,32831671 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,32325534 0,33161787 ! cellular respiration GO:0045333 107 79 0,000 0,32325534 0,33147003 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,32325534 0,33132231 ! regulation of lyase activity GO:0051339 133 79 0,000 0,32325534 0,33117473 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,32325534 0,33102728 ! chromatin assembly GO:0031497 102 80 0,000 0,32659959 0,3343031 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,32659959 0,33415438 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,32659959 0,33400581 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,32659959 0,33385736 ! forebrain development GO:0030900 131 80 0,000 0,32659959 0,33370904 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,32992751 0,33695971 ! hemostasis GO:0007599 125 81 0,000 0,32992751 0,33681015 ! mRNA transport GO:0051028 121 81 0,000 0,32992751 0,33666072 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,32992751 0,33651143 ! regulation of neurological system process GO:0031644 122 81 0,000 0,32992751 0,33636226 ! vitamin metabolic process GO:0006766 103 81 0,000 0,32992751 0,33621323 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,33653465 0,34279438 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,33653465 0,34264263 ! regulation of defense response GO:0031347 117 84 0,000 0,33981404 0,34582845 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,33981404 0,34567549 ! sterol metabolic process GO:0016125 120 84 0,000 0,33981404 0,34552268 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,3430774 0,34868671 ! rRNA metabolic process GO:0016072 107 85 0,000 0,3430774 0,3485327 GO:0006364|rRNA processing, ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,34632482 0,35167642 ! nucleosome organization GO:0034728 114 87 0,000 0,34955637 0,35480126 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,34955637 0,35464475 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,34955637 0,35448839 ! female pregnancy GO:0007565 130 87 0,000 0,34955637 0,35433215 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,35277213 0,35743432 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,35277213 0,35727693 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,35277213 0,35711968 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,35277213 0,35696256 ! reproductive developmental process GO:0003006 127 89 0,000 0,35597218 0,36004222 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,35597218 0,35988396 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,35597218 0,35972584 ! hormone metabolic process GO:0042445 121 90 0,000 0,35915659 0,36278443 ! RNA localization GO:0006403 135 91 0,000 0,36232543 0,36582462 ! ATP metabolic process GO:0046034 137 91 0,000 0,36232543 0,3656641 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,36547879 0,36868474 ! positive regulation of immune response GO:0050778 121 92 0,000 0,36547879 0,36852311 ! DNA recombination GO:0006310 146 92 0,000 0,36547879 0,36836162 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,36861673 0,37136158 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,36861673 0,37119898 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,36861673 0,37103653 ! electron transport chain GO:0022900 123 94 0,000 0,37173933 0,37401595 ! response to oxidative stress GO:0006979 141 94 0,000 0,37173933 0,37385241 ! carboxylic acid transport GO:0046942 147 95 0,000 0,37484667 0,37681265 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,37793882 0,37975504 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,37793882 0,37958921 ! protein maturation GO:0051604 129 96 0,000 0,37793882 0,37942352 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,38101585 0,38234575 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,38101585 0,38217901 ! calcium ion transport GO:0006816 167 99 0,000 0,38712485 0,38813739 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,38712485 0,38796826 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,39015697 0,39083668 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,39015697 0,39066653 ! divalent metal ion transport GO:0070838 171 100 0,000 0,39015697 0,39049653 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,39015697 0,39032668 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,39015697 0,39015697