pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6556-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 5,111E-07 1,23E-03 ! activation of MAPKKK activity GO:0000185 12 6 2,000 9,406E-07 1,132E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 1,171E-06 9,393E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,62E-06 1,576E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 3,919E-06 1,886E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 5,584E-06 2,239E-03 ! androgen receptor signaling pathway GO:0030521 74 36 3,000 9,067E-06 3,117E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 2,089E-05 6,283E-03 ! activation of MAPKK activity GO:0000186 35 16 2,000 2,564E-05 6,856E-03 ! cell cycle arrest GO:0007050 213 100 4,000 3,388E-05 8,153E-03 ! response to UV GO:0009411 104 53 3,000 4,297E-05 9,399E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 8,5E-05 0,01704184 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 1,028E-04 0,01903166 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,082E-04 0,01858647 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,146E-04 0,01837999 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 1,146E-04 0,01723124 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,301E-04 0,01841023 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,312E-04 0,01754347 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,312E-04 0,01662013 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,312E-04 0,01578912 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,312E-04 0,01503726 ! microvillus organization GO:0032528 7 5 1,000 1,312E-04 0,01435375 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 1,000 1,312E-04 0,01372967 ! sister chromatid cohesion GO:0007062 12 5 1,000 1,312E-04 0,0131576 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,312E-04 0,0126313 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,312E-04 0,01214548 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,431E-04 0,01275559 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,616E-04 0,01388941 ! lymphocyte differentiation GO:0030098 167 75 3,000 1,677E-04 0,01391317 ! protein oligomerization GO:0051259 139 78 3,000 1,952E-04 0,01565183 ! male meiosis GO:0007140 7 6 1,000 1,964E-04 0,01524329 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,964E-04 0,01476694 ! activation of protein kinase activity GO:0032147 147 79 3,000 2,05E-04 0,0149459 ! regulation of helicase activity GO:0051095 15 7 1,000 2,743E-04 0,01941115 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,743E-04 0,01885654 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,743E-04 0,01833275 ! mRNA stabilization GO:0048255 18 7 1,000 2,743E-04 0,01783727 GO:0043489|RNA stabilization, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 2,743E-04 0,01736787 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,743E-04 0,01692254 ! B cell lineage commitment GO:0002326 21 7 1,000 2,743E-04 0,01649947 ! T cell lineage commitment GO:0002360 16 7 1,000 2,743E-04 0,01609705 ! response to tumor cell GO:0002347 13 7 1,000 2,743E-04 0,01571379 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,649E-04 0,02041561 ! succinate metabolic process GO:0006105 14 8 1,000 3,649E-04 0,01995161 ! T-helper 1 type immune response GO:0042088 12 8 1,000 3,649E-04 0,01950824 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,649E-04 0,01908415 ! ER overload response GO:0006983 12 8 1,000 3,649E-04 0,01867811 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 3,649E-04 0,01828898 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,649E-04 0,01791574 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 3,649E-04 0,01755742 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 3,649E-04 0,01721316 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 3,83E-04 0,01772336 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 4,153E-04 0,01885438 ! mesenchymal cell development GO:0014031 87 40 2,000 4,245E-04 0,01891252 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! leukocyte differentiation GO:0002521 202 96 3,000 4,322E-04 0,01890578 ! T cell differentiation GO:0030217 81 41 2,000 4,568E-04 0,01962471 ! interphase GO:0051325 213 98 3,000 4,673E-04 0,01972611 ! induction of positive chemotaxis GO:0050930 15 9 1,000 4,68E-04 0,01941375 ! phosphagen metabolic process GO:0006599 12 9 1,000 4,68E-04 0,0190847 GO:0006600|creatine metabolic process, ! motor axon guidance GO:0008045 16 9 1,000 4,68E-04 0,01876662 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 4,906E-04 0,01935058 ! B cell differentiation GO:0030183 107 44 2,000 5,63E-04 0,0218477 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 5,836E-04 0,0222879 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 5,836E-04 0,02193966 ! lung alveolus development GO:0048286 26 10 1,000 5,836E-04 0,02160212 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 5,836E-04 0,02127482 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 5,836E-04 0,02095728 ! regulation of bone resorption GO:0045124 25 10 1,000 5,836E-04 0,02064909 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 5,836E-04 0,02034983 ! detection of calcium ion GO:0005513 23 10 1,000 5,836E-04 0,02005911 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 5,836E-04 0,01977659 ! localization within membrane GO:0051668 20 10 1,000 5,836E-04 0,01950192 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 6,016E-04 0,01982833 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 6,419E-04 0,02086966 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 6,419E-04 0,0205914 ! protein homooligomerization GO:0051260 76 47 2,000 6,838E-04 0,02164849 ! negative regulation of muscle development GO:0048635 20 11 1,000 7,116E-04 0,02223473 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 7,116E-04 0,02194967 ! blood vessel remodeling GO:0001974 29 11 1,000 7,116E-04 0,02167183 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 7,116E-04 0,02140093 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 7,116E-04 0,02113672 ! regulation of intracellular pH GO:0051453 19 11 1,000 7,116E-04 0,02087896 ! regulation of leukocyte migration GO:0002685 26 11 1,000 7,116E-04 0,0206274 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 7,275E-04 0,02083721 ! histone modification GO:0016570 91 50 2,000 8,2E-04 0,0232118 ! regulation of B cell proliferation GO:0030888 20 12 1,000 8,519E-04 0,02383244 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 8,519E-04 0,0235585 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 8,519E-04 0,02329079 ! mitotic spindle organization GO:0007052 21 12 1,000 8,519E-04 0,0230291 ! histone acetylation GO:0016573 26 12 1,000 8,519E-04 0,02277322 ! peptidyl-lysine modification GO:0018205 21 12 1,000 8,519E-04 0,02252296 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 8,519E-04 0,02227815 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 8,519E-04 0,0220386 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 2,000 8,69E-04 0,02224223 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 8,69E-04 0,0220081 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! covalent chromatin modification GO:0016569 101 52 2,000 9,197E-04 0,02305112 ! pseudouridine synthesis GO:0001522 17 13 1,000 1,004E-03 0,02491203 ! response to X-ray GO:0010165 25 13 1,000 1,004E-03 0,02465783 ! regulation of cellular pH GO:0030641 22 13 1,000 1,004E-03 0,02440876 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,004E-03 0,02416467 ! chromatin silencing GO:0006342 26 13 1,000 1,004E-03 0,02392542 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,004E-03 0,02369085 ! RNA elongation GO:0006354 79 55 2,000 1,083E-03 0,0253026 ! regulation of DNA replication GO:0006275 101 56 2,000 1,141E-03 0,02640776 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,169E-03 0,02678564 ! regulation of mRNA processing GO:0050684 24 14 1,000 1,169E-03 0,02653294 ! response to gamma radiation GO:0010332 28 14 1,000 1,169E-03 0,02628497 ! regulation of RNA stability GO:0043487 32 14 1,000 1,169E-03 0,02604159 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,169E-03 0,02580268 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,202E-03 0,02628476 ! regulation of bone remodeling GO:0046850 137 57 2,000 1,202E-03 0,02604796 ! positive regulation of cell migration GO:0030335 126 57 2,000 1,202E-03 0,02581539 ! regulation of intracellular transport GO:0032386 101 57 2,000 1,202E-03 0,02558693 ! regulation of tissue remodeling GO:0034103 140 58 2,000 1,264E-03 0,02667522 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,346E-03 0,02815174 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,346E-03 0,02790905 ! regulation of exocytosis GO:0017157 22 15 1,000 1,346E-03 0,02767051 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,346E-03 0,02743602 ! histone deacetylation GO:0016575 20 15 1,000 1,346E-03 0,02720546 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 1,394E-03 0,02795594 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,534E-03 0,03050519 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,534E-03 0,03025515 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,534E-03 0,03000917 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,534E-03 0,02976717 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,534E-03 0,02952903 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,534E-03 0,02929467 ! defense response to virus GO:0051607 37 16 1,000 1,534E-03 0,029064 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,68E-03 0,03157425 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 1,735E-03 0,03235129 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,735E-03 0,03210243 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,735E-03 0,03185737 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 1,735E-03 0,03161603 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,735E-03 0,03137832 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,916E-03 0,03440448 ! lung development GO:0030324 144 67 2,000 1,916E-03 0,03414963 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 1,916E-03 0,03389853 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,947E-03 0,03418834 ! negative regulation of cell size GO:0045792 134 69 2,000 2,085E-03 0,03634519 ! lipid phosphorylation GO:0046834 35 19 1,000 2,171E-03 0,03757106 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 2,171E-03 0,03730269 ! neuromuscular junction development GO:0007528 34 19 1,000 2,171E-03 0,03703814 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 2,171E-03 0,0367773 ! G1 phase GO:0051318 40 19 1,000 2,171E-03 0,03652012 ! respiratory tube development GO:0030323 150 70 2,000 2,172E-03 0,03629441 ! B cell activation GO:0042113 160 71 2,000 2,262E-03 0,03753505 ! regulation of caspase activity GO:0043281 122 72 2,000 2,354E-03 0,03879618 ! respiratory system development GO:0060541 153 72 2,000 2,354E-03 0,03853226 ! protein amino acid deacetylation GO:0006476 29 20 1,000 2,406E-03 0,03911374 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,406E-03 0,03885123 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 2,406E-03 0,03859222 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,406E-03 0,03833664 ! cellular response to starvation GO:0009267 33 20 1,000 2,406E-03 0,03808443 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 2,406E-03 0,03783551 ! detection of chemical stimulus GO:0009593 37 20 1,000 2,406E-03 0,03758983 ! negative regulation of T cell activation GO:0050868 40 20 1,000 2,406E-03 0,03734731 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,406E-03 0,03710791 ! meiosis GO:0007126 121 74 2,000 2,545E-03 0,03900746 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 2,545E-03 0,03876058 ! meiotic cell cycle GO:0051321 122 75 2,000 2,644E-03 0,04001594 ! cell aging GO:0007569 44 21 1,000 2,653E-03 0,03989352 ! positive regulation of locomotion GO:0040017 39 21 1,000 2,653E-03 0,03964573 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 41 21 1,000 2,653E-03 0,03940101 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 2,653E-03 0,03915928 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,911E-03 0,04271074 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 2,911E-03 0,04245189 ! regulation of chemotaxis GO:0050920 40 22 1,000 2,911E-03 0,04219615 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,911E-03 0,04194348 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,911E-03 0,04169382 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,911E-03 0,04144711 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 2,956E-03 0,0418338 ! regulation of peptidase activity GO:0052547 134 79 2,000 3,064E-03 0,04311698 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 3,064E-03 0,0428663 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 3,181E-03 0,04423943 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 3,181E-03 0,04398518 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 3,181E-03 0,04373384 ! T cell activation GO:0042110 168 81 2,000 3,289E-03 0,04496053 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 3,289E-03 0,04470652 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 2,000 3,289E-03 0,04445536 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 3,405E-03 0,04576497 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 3,462E-03 0,04627412 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 3,462E-03 0,04601846 ! regulation of behavior GO:0050795 43 24 1,000 3,462E-03 0,04576561 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,462E-03 0,04551553 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 3,462E-03 0,04526816 ! protein tetramerization GO:0051262 52 24 1,000 3,462E-03 0,04502347 ! response to oxygen levels GO:0070482 176 83 2,000 3,523E-03 0,04557396 ! negative regulation of growth GO:0045926 155 84 2,000 3,644E-03 0,04688545 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 3,754E-03 0,04804318 ! myelination GO:0042552 45 25 1,000 3,754E-03 0,04778899 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 3,754E-03 0,04753747 ! vasculogenesis GO:0001570 46 25 1,000 3,754E-03 0,04728858 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 3,754E-03 0,04704228 ! negative regulation of DNA replication GO:0008156 42 25 1,000 3,754E-03 0,04679854 ! response to starvation GO:0042594 42 25 1,000 3,754E-03 0,04655731 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,754E-03 0,04631856 ! negative regulation of cell development GO:0010721 73 25 1,000 3,754E-03 0,04608224 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 3,754E-03 0,04584832 ! cellular response to nutrient levels GO:0031669 41 25 1,000 3,754E-03 0,04561676 ! regulation of protein transport GO:0051223 154 87 2,000 4,022E-03 0,04862505 GO:0070201|regulation of establishment of protein localization, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 4,057E-03 0,04880775 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 4,057E-03 0,04856492 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 4,057E-03 0,0483245 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 4,057E-03 0,04808645 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 4,057E-03 0,04785073 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 4,057E-03 0,04761732 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 4,371E-03 0,05105551 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 4,371E-03 0,05080887 ! protein amino acid acylation GO:0043543 55 27 1,000 4,371E-03 0,0505646 ! mitochondrial membrane organization GO:0007006 57 27 1,000 4,371E-03 0,05032266 ! base-excision repair GO:0006284 41 27 1,000 4,371E-03 0,05008303 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 4,371E-03 0,04984567 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 4,696E-03 0,05329989 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 4,696E-03 0,05304966 ! transcription initiation GO:0006352 153 94 2,000 4,993E-03 0,05613843 ! regulation of pH GO:0006885 43 29 1,000 5,032E-03 0,05631523 ! tissue homeostasis GO:0001894 48 29 1,000 5,032E-03 0,05605452 GO:0048871|multicellular organismal homeostasis, ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 5,379E-03 0,05963978 ! ensheathment of neurons GO:0007272 57 30 1,000 5,379E-03 0,05936621 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 5,379E-03 0,05909513 ! neurotransmitter secretion GO:0007269 48 30 1,000 5,379E-03 0,05882651 ! regulation of B cell activation GO:0050864 50 30 1,000 5,379E-03 0,05856033 ! response to heat GO:0009408 50 30 1,000 5,379E-03 0,05829654 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 5,449E-03 0,058791 ! regulation of protein localization GO:0032880 176 97 2,000 5,449E-03 0,05852854 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 5,736E-03 0,06134024 ! inner ear morphogenesis GO:0042472 47 31 1,000 5,736E-03 0,06106882 ! skeletal muscle tissue development GO:0007519 186 99 2,000 5,766E-03 0,06111856 GO:0060538|skeletal muscle organ development, ! spindle organization GO:0007051 46 32 1,000 6,104E-03 0,06441554 ! response to ionizing radiation GO:0010212 65 32 1,000 6,104E-03 0,06413425 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 6,104E-03 0,06385541 ! peripheral nervous system development GO:0007422 64 32 1,000 6,104E-03 0,06357898 ! positive regulation of catabolic process GO:0009896 64 32 1,000 6,104E-03 0,06330493 ! gene silencing GO:0016458 65 32 1,000 6,104E-03 0,06303323 ! DNA damage checkpoint GO:0000077 71 33 1,000 6,483E-03 0,06665473 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 6,483E-03 0,06637109 ! negative regulation of protein transport GO:0051224 69 33 1,000 6,483E-03 0,06608986 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 6,871E-03 0,06975845 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 6,871E-03 0,06946535 ! regulation of muscle development GO:0048634 70 35 1,000 7,271E-03 0,07319325 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 7,271E-03 0,07288828 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 7,271E-03 0,07258584 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 7,271E-03 0,0722859 ! calcium-mediated signaling GO:0019722 62 35 1,000 7,271E-03 0,07198842 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 7,68E-03 0,07573082 ! DNA integrity checkpoint GO:0031570 75 36 1,000 7,68E-03 0,07542171 ! negative regulation of cell activation GO:0050866 65 36 1,000 7,68E-03 0,07511512 ! tissue remodeling GO:0048771 76 37 1,000 8,1E-03 0,07889863 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 8,1E-03 0,07858049 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 8,1E-03 0,07826491 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 8,529E-03 0,08208769 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 8,529E-03 0,08176065 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 8,969E-03 0,08563499 ! ear morphogenesis GO:0042471 60 39 1,000 8,969E-03 0,08529651 ! segmentation GO:0035282 67 39 1,000 8,969E-03 0,0849607 ! regulation of action potential in neuron GO:0019228 73 39 1,000 8,969E-03 0,08462752 ! RNA modification GO:0009451 57 39 1,000 8,969E-03 0,08429694 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 9,419E-03 0,08817921 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 9,419E-03 0,08783743 ! cellular amide metabolic process GO:0043603 67 41 1,000 9,879E-03 0,09176778 ! regulation of T cell proliferation GO:0042129 71 41 1,000 9,879E-03 0,09141482 ! regulation of T cell differentiation GO:0045580 70 41 1,000 9,879E-03 0,09106458 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01034797 0,09502759 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 79 43 1,000 0,0108271 0,0990494 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,0108271 0,09867421 ! double-strand break repair GO:0006302 81 44 1,000 0,01131586 0,10273949 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01131586 0,10235325 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,0118142 0,10646054 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01232203 0,11062243 ! response to insulin stimulus GO:0032868 95 46 1,000 0,01232203 0,11021119 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01232203 0,10980301 ! response to calcium ion GO:0051592 81 47 1,000 0,01283929 0,11399012 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01283929 0,11357104 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01283929 0,11315503 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,01336589 0,11736614 ! mitochondrial transport GO:0006839 82 48 1,000 0,01336589 0,11693936 ! activation of caspase activity GO:0006919 84 48 1,000 0,01336589 0,11651567 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01336589 0,11609503 ! regulation of action potential GO:0001508 95 49 1,000 0,01390176 0,12031523 ! response to temperature stimulus GO:0009266 76 49 1,000 0,01390176 0,11988399 ! regulation of ossification GO:0030278 117 50 1,000 0,01444683 0,12413956 ! inner ear development GO:0048839 79 50 1,000 0,01444683 0,12369778 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01444683 0,12325914 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01444683 0,12282359 ! positive regulation of binding GO:0051099 78 51 1,000 0,01500103 0,12708619 ! chromatin remodeling GO:0006338 109 51 1,000 0,01500103 0,12664027 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,01500103 0,12619747 ! regulation of cell shape GO:0008360 125 51 1,000 0,01500103 0,12575776 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01556428 0,13002659 ! positive regulation of growth GO:0045927 90 52 1,000 0,01556428 0,12957668 ! synapse organization GO:0050808 85 52 1,000 0,01556428 0,12912986 ! regulation of translational initiation GO:0006446 82 53 1,000 0,01613651 0,13341736 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01613651 0,13296045 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01671765 0,13727876 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,01671765 0,13681183 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01730763 0,14115989 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01730763 0,140683 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,01730763 0,14020932 ! aging GO:0007568 103 55 1,000 0,01730763 0,13973882 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01730763 0,13927147 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01790638 0,14360918 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01790638 0,14313207 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01813039 0,14444278 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01813039 0,14396607 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01813039 0,1434925 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01813039 0,14302203 ! neuron fate determination GO:0048664 7 5 0,000 0,01813039 0,14255464 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01813039 0,14209029 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01813039 0,14162896 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01813039 0,14117062 ! polyol transport GO:0015791 12 5 0,000 0,01813039 0,14071523 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01813039 0,14026277 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01813039 0,13981321 ! response to superoxide GO:0000303 10 5 0,000 0,01813039 0,13936652 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01813039 0,13892268 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01813039 0,13848165 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01813039 0,13804342 ! female meiosis GO:0007143 7 5 0,000 0,01813039 0,13760795 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01813039 0,13717522 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01813039 0,1367452 ! cobalt ion transport GO:0006824 11 5 0,000 0,01813039 0,13631788 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01813039 0,13589321 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01813039 0,13547118 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01813039 0,13505177 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01813039 0,13463494 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01813039 0,13422068 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01813039 0,13380896 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01813039 0,13339976 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01813039 0,13299305 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01813039 0,13258882 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01813039 0,13218703 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01813039 0,13178767 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01813039 0,13139072 ! negative chemotaxis GO:0050919 14 5 0,000 0,01813039 0,13099616 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01813039 0,13060395 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01813039 0,13021409 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01813039 0,12982655 ! behavioral response to pain GO:0048266 9 5 0,000 0,01813039 0,12944131 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01813039 0,12905834 ! Notch receptor processing GO:0007220 8 5 0,000 0,01813039 0,12867764 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01813039 0,12829918 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01813039 0,12792293 ! micturition GO:0060073 9 5 0,000 0,01813039 0,12754889 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01813039 0,12717703 ! copulation GO:0007620 9 5 0,000 0,01813039 0,12680733 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01813039 0,12643977 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01813039 0,12607434 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01813039 0,12571101 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01813039 0,12534977 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01813039 0,1249906 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01813039 0,12463349 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01813039 0,12427841 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01813039 0,12392534 ! grooming behavior GO:0007625 6 5 0,000 0,01813039 0,12357428 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01813039 0,1232252 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01813039 0,12287809 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01813039 0,12253292 ! response to protozoan GO:0001562 10 5 0,000 0,01813039 0,12218969 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01813039 0,12184838 ! lymph vessel development GO:0001945 10 5 0,000 0,01813039 0,12150897 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01813039 0,12117145 ! endochondral ossification GO:0001958 16 5 0,000 0,01813039 0,12083579 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01813039 0,12050199 ! parathyroid gland development GO:0060017 13 5 0,000 0,01813039 0,12017003 ! anagen GO:0042640 6 5 0,000 0,01813039 0,11983989 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01813039 0,11951156 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01813039 0,11918503 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01813039 0,11886027 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01813039 0,11853728 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01813039 0,11821604 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01813039 0,11789654 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01813039 0,11757876 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01813039 0,11726269 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01813039 0,11694831 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01813039 0,11663562 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01813039 0,11632459 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01813039 0,11601521 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01813039 0,11570748 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01813039 0,11540138 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01813039 0,11509689 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01813039 0,114794 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01813039 0,1144927 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01813039 0,11419299 ! histidine catabolic process GO:0006548 6 5 0,000 0,01813039 0,11389483 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01813039 0,11359823 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01813039 0,11330317 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01813039 0,11300964 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01813039 0,11271762 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01813039 0,11242711 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01813039 0,1121381 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01813039 0,11185056 ! polyol catabolic process GO:0046174 7 5 0,000 0,01813039 0,1115645 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01813039 0,1112799 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01813039 0,11099674 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01813039 0,11071503 ! muscle cell migration GO:0014812 8 5 0,000 0,01813039 0,11043473 ! mitochondrial fission GO:0000266 8 5 0,000 0,01813039 0,11015586 ! mRNA transcription GO:0009299 9 5 0,000 0,01813039 0,10987839 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01813039 0,10960231 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01813039 0,10932762 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01813039 0,1090543 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01813039 0,10878234 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01813039 0,10851174 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01813039 0,10824248 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01813039 0,10797456 ! response to food GO:0032094 6 5 0,000 0,01813039 0,10770795 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01813039 0,10744266 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01813039 0,10717867 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01813039 0,10691598 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01813039 0,10665457 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01813039 0,10639444 ! forebrain neuron development GO:0021884 13 5 0,000 0,01813039 0,10613557 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01813039 0,10587796 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01813039 0,1056216 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01813039 0,10536647 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01813039 0,10511258 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01813039 0,1048599 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01813039 0,10460844 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01813039 0,10435818 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01813039 0,10410912 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01813039 0,10386124 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01813039 0,10361454 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01813039 0,10336901 ! basic amino acid transport GO:0015802 11 5 0,000 0,01813039 0,10312463 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01813039 0,10288142 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01813039 0,10263934 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01813039 0,1023984 ! depyrimidination GO:0045008 10 5 0,000 0,01813039 0,1021586 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01813039 0,10191991 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01813039 0,10168233 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01813039 0,10144586 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01813039 0,10121049 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01813039 0,1009762 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01813039 0,100743 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01813039 0,10051088 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01813039 0,10027982 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01813039 0,10004982 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01813039 0,09982087 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01813039 0,09959297 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01813039 0,09936611 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01813039 0,09914027 ! response to arsenic GO:0046685 10 5 0,000 0,01813039 0,09891547 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01813039 0,09869167 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01813039 0,09846889 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01813039 0,09824712 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01813039 0,09802634 ! response to cadmium ion GO:0046686 7 5 0,000 0,01813039 0,09780655 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01813039 0,09758774 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01813039 0,09736991 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01813039 0,09715305 ! decidualization GO:0046697 11 5 0,000 0,01813039 0,09693716 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01813039 0,09672222 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01813039 0,09650823 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01813039 0,09629519 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01813039 0,09608308 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01813039 0,09587191 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01813039 0,09566167 ! neural tube patterning GO:0021532 7 5 0,000 0,01813039 0,09545234 ! embryonic cleavage GO:0040016 6 5 0,000 0,01813039 0,09524393 ! peroxisome fission GO:0016559 5 5 0,000 0,01813039 0,09503643 ! histone demethylation GO:0016577 10 5 0,000 0,01813039 0,09482983 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01813039 0,09462412 ! mitotic recombination GO:0006312 9 5 0,000 0,01813039 0,09441931 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01813039 0,09421538 ! metaphase plate congression GO:0051310 7 5 0,000 0,01813039 0,09401233 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01813039 0,09381015 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01813039 0,09360884 ! enteric nervous system development GO:0048484 8 5 0,000 0,01813039 0,09340839 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01813039 0,0932088 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01813039 0,09301006 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01813039 0,09281217 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01813039 0,09261512 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01813039 0,0924189 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01813039 0,09222351 ! plasminogen activation GO:0031639 5 5 0,000 0,01813039 0,09202895 ! B cell homeostasis GO:0001782 13 5 0,000 0,01813039 0,0918352 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01813039 0,09164227 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01813039 0,09145015 ! metaphase GO:0051323 8 5 0,000 0,01813039 0,09125883 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01813039 0,09106831 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01813039 0,09087858 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01813039 0,09068965 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01813039 0,09050149 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01813039 0,09031412 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01813039 0,09012752 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01813039 0,08994169 ! response to redox state GO:0051775 5 5 0,000 0,01813039 0,08975663 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01813039 0,08957232 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01813039 0,08938877 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01813039 0,08920597 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01813039 0,08902392 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01813039 0,08884261 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01813039 0,08866203 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01813039 0,08848219 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01813039 0,08830308 ! striatum development GO:0021756 9 5 0,000 0,01813039 0,08812469 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01813039 0,08794702 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01813039 0,08777006 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01813039 0,08759382 ! glial cell migration GO:0008347 11 5 0,000 0,01813039 0,08741828 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01813039 0,08724344 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01813039 0,0870693 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01813039 0,08689586 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01813039 0,0867231 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01813039 0,08655103 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01813039 0,08637964 ! neuroprotection GO:0043526 6 5 0,000 0,01813039 0,08620893 ! neural plate development GO:0001840 8 5 0,000 0,01813039 0,0860389 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01813039 0,08586953 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01813039 0,08570083 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01813039 0,08553278 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01813039 0,0853654 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01813039 0,08519867 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01813039 0,08503259 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01813039 0,08486716 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01813039 0,08470237 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01813039 0,08453822 ! spindle assembly GO:0051225 6 5 0,000 0,01813039 0,0843747 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01813039 0,08421182 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01813039 0,08404956 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01813039 0,08388792 ! drug metabolic process GO:0017144 6 5 0,000 0,01813039 0,08372691 ! stem cell division GO:0017145 11 5 0,000 0,01813039 0,08356651 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01813039 0,08340673 ! organ regeneration GO:0031100 7 5 0,000 0,01813039 0,08324756 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01813039 0,08308899 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01813039 0,08293103 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01813039 0,08277366 ! muscle fiber development GO:0048747 112 57 1,000 0,01851382 0,08436413 ! lipid modification GO:0030258 97 57 1,000 0,01851382 0,08420465 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01851382 0,08404577 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01912989 0,08667894 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,02038763 0,09220419 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,02038763 0,0920312 ! tRNA processing GO:0008033 89 61 1,000 0,02102915 0,09474933 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,02102915 0,09457223 ! ear development GO:0043583 103 62 1,000 0,02167903 0,09731296 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,02167903 0,09713174 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02171719 0,09712185 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02171719 0,09694166 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02171719 0,09676214 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02171719 0,09658328 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02171719 0,09640508 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02171719 0,09622754 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02171719 0,09605065 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02171719 0,09587441 ! sleep GO:0030431 13 6 0,000 0,02171719 0,09569882 ! response to oxygen radical GO:0000305 11 6 0,000 0,02171719 0,09552387 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02171719 0,09534955 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02171719 0,09517588 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02171719 0,09500283 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02171719 0,09483041 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02171719 0,09465862 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02171719 0,09448744 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02171719 0,09431689 ! forebrain regionalization GO:0021871 8 6 0,000 0,02171719 0,09414695 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02171719 0,09397762 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02171719 0,0938089 ! response to zinc ion GO:0010043 9 6 0,000 0,02171719 0,09364078 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02171719 0,09347327 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02171719 0,09330635 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02171719 0,09314003 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02171719 0,0929743 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02171719 0,09280916 ! malate metabolic process GO:0006108 11 6 0,000 0,02171719 0,0926446 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02171719 0,09248063 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02171719 0,09231724 ! protein refolding GO:0042026 15 6 0,000 0,02171719 0,09215442 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02171719 0,09199218 ! opsonization GO:0008228 8 6 0,000 0,02171719 0,0918305 ! mating behavior GO:0007617 7 6 0,000 0,02171719 0,0916694 ! neuron remodeling GO:0016322 15 6 0,000 0,02171719 0,09150885 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02171719 0,09134887 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02171719 0,09118945 ! equilibrioception GO:0050957 14 6 0,000 0,02171719 0,09103059 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02171719 0,09087227 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02171719 0,09071451 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02171719 0,09055729 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02171719 0,09040062 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02171719 0,09024448 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02171719 0,09008889 ! toxin metabolic process GO:0009404 11 6 0,000 0,02171719 0,08993383 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02171719 0,08977931 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02171719 0,08962531 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02171719 0,08947184 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02171719 0,0893189 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02171719 0,08916648 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02171719 0,08901458 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02171719 0,08886319 ! thymic T cell selection GO:0045061 12 6 0,000 0,02171719 0,08871232 ! protein lipoylation GO:0009249 10 6 0,000 0,02171719 0,08856196 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02171719 0,08841211 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02171719 0,08826276 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02171719 0,08811392 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02171719 0,08796558 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02171719 0,08781774 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02171719 0,0876704 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02171719 0,08752354 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02171719 0,08737718 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02171719 0,08723131 ! hyperosmotic response GO:0006972 9 6 0,000 0,02171719 0,08708593 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02171719 0,08694102 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02171719 0,0867966 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02171719 0,08665266 ! urea metabolic process GO:0019627 7 6 0,000 0,02171719 0,0865092 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02171719 0,08636621 ! neutrophil activation GO:0042119 8 6 0,000 0,02171719 0,08622369 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02171719 0,08608164 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02171719 0,08594006 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02171719 0,08579894 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02171719 0,08565829 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02171719 0,08551809 ! neuron apoptosis GO:0051402 9 6 0,000 0,02171719 0,08537836 ! nucleoside salvage GO:0043174 9 6 0,000 0,02171719 0,08523908 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02171719 0,08510025 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02171719 0,08496188 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02171719 0,08482395 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02171719 0,08468648 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02171719 0,08454944 ! carnitine transport GO:0015879 10 6 0,000 0,02171719 0,08441285 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02171719 0,0842767 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02171719 0,08414099 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02171719 0,08400572 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02171719 0,08387088 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02171719 0,08373647 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02171719 0,08360249 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02171719 0,08346894 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02171719 0,08333581 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02171719 0,08320311 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02171719 0,08307084 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02171719 0,08293898 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02171719 0,08280754 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02171719 0,08267651 ! neural nucleus development GO:0048857 14 6 0,000 0,02171719 0,0825459 ! response to UV-C GO:0010225 11 6 0,000 0,02171719 0,0824157 ! astrocyte development GO:0014002 15 6 0,000 0,02171719 0,08228591 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02171719 0,08215653 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02171719 0,08202756 ! interaction with symbiont GO:0051702 13 6 0,000 0,02171719 0,08189899 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02171719 0,08177082 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02171719 0,08164306 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02171719 0,08151569 ! response to copper ion GO:0046688 10 6 0,000 0,02171719 0,08138872 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02171719 0,08126214 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02171719 0,08113596 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02171719 0,08101016 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02171719 0,08088476 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02171719 0,08075975 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02171719 0,08063512 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02171719 0,08051087 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02171719 0,08038701 ! hair follicle maturation GO:0048820 7 6 0,000 0,02171719 0,08026353 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02171719 0,08014042 ! Schwann cell development GO:0014044 15 6 0,000 0,02171719 0,0800177 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02171719 0,07989535 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02171719 0,07977337 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02171719 0,07965176 ! subpallium development GO:0021544 10 6 0,000 0,02171719 0,07953053 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02171719 0,07940966 ! histone ubiquitination GO:0016574 8 6 0,000 0,02171719 0,07928916 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02171719 0,07916902 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02171719 0,07904925 ! G2 phase GO:0051319 16 6 0,000 0,02171719 0,07892984 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02171719 0,07881079 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02171719 0,0786921 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02171719 0,07857377 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02171719 0,07845579 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02171719 0,07833816 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02171719 0,07822089 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02171719 0,07810397 ! receptor internalization GO:0031623 10 6 0,000 0,02171719 0,0779874 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02171719 0,07787117 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02171719 0,07775529 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02171719 0,07763976 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02171719 0,07752456 ! protein deubiquitination GO:0016579 14 6 0,000 0,02171719 0,07740971 ! protein destabilization GO:0031648 9 6 0,000 0,02171719 0,0772952 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02171719 0,07718103 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02171719 0,07706719 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02171719 0,07695369 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02171719 0,07684052 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02171719 0,07672769 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02171719 0,07661518 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02171719 0,07650301 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02171719 0,07639116 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02171719 0,07627964 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02171719 0,07616845 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02171719 0,07605758 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02171719 0,07594703 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02171719 0,0758368 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02171719 0,07572689 ! catecholamine transport GO:0051937 9 6 0,000 0,02171719 0,0756173 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02171719 0,07550803 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02171719 0,07539907 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02171719 0,07529043 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02171719 0,07518209 ! maternal placenta development GO:0001893 12 6 0,000 0,02171719 0,07507407 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02171719 0,07496636 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02171719 0,07485896 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02171719 0,07475187 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02171719 0,07464508 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02171719 0,0745386 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02171719 0,07443242 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02171719 0,07432654 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,02367807 0,08092249 GO:0035113|embryonic appendage morphogenesis, ! cell projection assembly GO:0030031 120 66 1,000 0,02436066 0,08313723 ! activation of MAPK activity GO:0000187 115 67 1,000 0,02505126 0,08537299 ! chromosome segregation GO:0007059 113 67 1,000 0,02505126 0,08525224 ! adaptive immune response GO:0002250 119 67 1,000 0,02505126 0,08513182 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! tRNA transcription GO:0009304 14 7 0,000 0,025291 0,08582532 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,025291 0,08570444 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,025291 0,0855839 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,025291 0,0854637 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,025291 0,08534383 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,025291 0,0852243 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,025291 0,08510511 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,025291 0,08498625 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,025291 0,08486772 ! prostate gland development GO:0030850 13 7 0,000 0,025291 0,08474952 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,025291 0,08463164 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,025291 0,0845141 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,025291 0,08439688 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,025291 0,08427999 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,025291 0,08416342 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,025291 0,08404717 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,025291 0,08393124 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,025291 0,08381564 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,025291 0,08370035 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,025291 0,08358537 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,025291 0,08347072 ! glycolipid transport GO:0046836 10 7 0,000 0,025291 0,08335637 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,025291 0,08324234 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,025291 0,08312862 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,025291 0,08301521 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,025291 0,08290211 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,025291 0,08278932 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,025291 0,08267684 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,025291 0,08256466 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,025291 0,08245278 ! pericardium development GO:0060039 14 7 0,000 0,025291 0,08234121 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,025291 0,08222994 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,025291 0,08211896 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,025291 0,08200829 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,025291 0,08189792 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,025291 0,08178784 ! lipoprotein transport GO:0042953 14 7 0,000 0,025291 0,08167806 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,025291 0,08156857 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,025291 0,08145937 ! rhythmic behavior GO:0007622 15 7 0,000 0,025291 0,08135047 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,025291 0,08124186 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,025291 0,08113354 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,025291 0,0810255 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,025291 0,08091776 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,025291 0,08081029 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,025291 0,08070312 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,025291 0,08059623 ! mechanosensory behavior GO:0007638 14 7 0,000 0,025291 0,08048962 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,025291 0,08038329 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,025291 0,08027725 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,025291 0,08017148 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,025291 0,08006599 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,025291 0,07996078 ! spinal cord patterning GO:0021511 13 7 0,000 0,025291 0,07985584 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,025291 0,07975118 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,025291 0,0796468 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,025291 0,07954268 ! adrenal gland development GO:0030325 17 7 0,000 0,025291 0,07943884 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,025291 0,07933527 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,025291 0,07923197 ! ovulation GO:0030728 9 7 0,000 0,025291 0,07912894 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,025291 0,07902617 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,025291 0,07892367 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,025291 0,07882144 ! microtubule nucleation GO:0007020 20 7 0,000 0,025291 0,07871947 ! proline biosynthetic process GO:0006561 10 7 0,000 0,025291 0,07861777 ! thyroid hormone generation GO:0006590 13 7 0,000 0,025291 0,07851633 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,025291 0,07841514 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,025291 0,07831422 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,025291 0,07821356 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,025291 0,07811316 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,025291 0,07801302 ! galactose metabolic process GO:0006012 13 7 0,000 0,025291 0,07791313 ! vesicle fusion GO:0006906 17 7 0,000 0,025291 0,07781349 ! response to dietary excess GO:0002021 8 7 0,000 0,025291 0,07771412 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,025291 0,07761499 ! intracellular pH reduction GO:0051452 11 7 0,000 0,025291 0,07751612 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,025291 0,0774175 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,025291 0,07731913 ! organ growth GO:0035265 15 7 0,000 0,025291 0,07722101 ! purine salvage GO:0043101 10 7 0,000 0,025291 0,07712313 ! nucleoside transport GO:0015858 8 7 0,000 0,025291 0,07702551 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,025291 0,07692813 ! parturition GO:0007567 14 7 0,000 0,025291 0,076831 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,025291 0,07673411 ! rRNA modification GO:0000154 14 7 0,000 0,025291 0,07663747 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,025291 0,07654107 ! spindle checkpoint GO:0031577 15 7 0,000 0,025291 0,07644491 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,025291 0,076349 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,025291 0,07625332 ! macrophage differentiation GO:0030225 11 7 0,000 0,025291 0,07615789 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,025291 0,07606269 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,025291 0,07596773 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,025291 0,07587301 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,025291 0,07577852 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,025291 0,07568427 ! fibrinolysis GO:0042730 10 7 0,000 0,025291 0,07559025 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,025291 0,07549647 ! eating behavior GO:0042755 7 7 0,000 0,025291 0,07540291 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,025291 0,07530959 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,025291 0,0752165 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,025291 0,07512364 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,025291 0,07503101 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,025291 0,07493861 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,025291 0,07484644 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,025291 0,07475449 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,025291 0,07466276 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,025291 0,07457126 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,025291 0,07447999 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,025291 0,07438894 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,025291 0,07429811 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,025291 0,0742075 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,025291 0,07411712 ! regulation of meiosis GO:0040020 12 7 0,000 0,025291 0,07402695 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,025291 0,073937 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,025291 0,07384727 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,025291 0,07375776 ! oxygen homeostasis GO:0032364 12 7 0,000 0,025291 0,07366846 ! transcription termination GO:0006353 13 7 0,000 0,025291 0,07357939 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,025291 0,07349052 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,025291 0,07340187 ! anaphase GO:0051322 17 7 0,000 0,025291 0,07331344 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,025291 0,07322521 ! axonal fasciculation GO:0007413 18 7 0,000 0,025291 0,0731372 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,025291 0,0730494 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,025291 0,07296181 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,025291 0,07287443 ! diuresis GO:0030146 12 7 0,000 0,025291 0,07278726 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,025291 0,0727003 ! thiamin metabolic process GO:0006772 7 7 0,000 0,025291 0,07261355 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,025291 0,072527 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,025291 0,07244066 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,025291 0,07235452 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,025291 0,07226859 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,025291 0,07218286 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,025291 0,07209734 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,025291 0,07201201 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,025291 0,07192689 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,025291 0,07184197 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,025291 0,07175725 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,025291 0,07167274 ! lymph node development GO:0048535 10 7 0,000 0,025291 0,07158841 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,025291 0,07150429 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,025291 0,07142037 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,025291 0,07133664 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,025291 0,07125311 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,025291 0,07116977 ! adult feeding behavior GO:0008343 9 7 0,000 0,025291 0,07108663 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,025291 0,07100368 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,025291 0,07092092 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,025291 0,07083836 ! muscle adaptation GO:0043500 14 7 0,000 0,025291 0,07075599 ! embryonic heart tube development GO:0035050 10 7 0,000 0,025291 0,07067381 ! retina homeostasis GO:0001895 12 7 0,000 0,025291 0,07059182 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,025291 0,07051003 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,025291 0,07042842 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,025291 0,070347 ! protein prenylation GO:0018342 18 7 0,000 0,025291 0,07026576 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,025291 0,07018472 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,025291 0,07010386 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,025291 0,07002319 ! regulation of lipase activity GO:0060191 130 68 1,000 0,0257498 0,07121153 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02645623 0,07308115 ! appendage morphogenesis GO:0035107 135 70 1,000 0,02717046 0,07496804 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,02789244 0,07687196 GO:0060173|limb development, ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02862211 0,07879267 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,02862211 0,07870262 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02885188 0,07924386 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02885188 0,0791535 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02885188 0,07906335 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02885188 0,0789734 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02885188 0,07888366 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02885188 0,07879412 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02885188 0,07870479 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02885188 0,07861565 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02885188 0,07852672 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02885188 0,07843799 ! meiotic prophase I GO:0007128 13 8 0,000 0,02885188 0,07834946 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02885188 0,07826113 ! oligopeptide transport GO:0006857 15 8 0,000 0,02885188 0,078173 ! UTP metabolic process GO:0046051 8 8 0,000 0,02885188 0,07808506 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02885188 0,07799733 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02885188 0,07790979 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02885188 0,07782244 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02885188 0,0777353 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02885188 0,07764835 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02885188 0,07756159 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02885188 0,07747502 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02885188 0,07738865 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02885188 0,07730247 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02885188 0,07721649 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02885188 0,07713069 ! reflex GO:0060004 16 8 0,000 0,02885188 0,07704508 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02885188 0,07695967 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02885188 0,07687444 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02885188 0,0767894 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02885188 0,07670455 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02885188 0,07661989 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02885188 0,07653541 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02885188 0,07645112 ! pigment granule organization GO:0048753 16 8 0,000 0,02885188 0,07636702 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02885188 0,0762831 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02885188 0,07619936 ! histidine metabolic process GO:0006547 16 8 0,000 0,02885188 0,07611581 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02885188 0,07603244 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02885188 0,07594926 ! glycine catabolic process GO:0006546 13 8 0,000 0,02885188 0,07586625 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02885188 0,07578343 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02885188 0,07570079 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02885188 0,07561832 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02885188 0,07553604 ! melanin metabolic process GO:0006582 15 8 0,000 0,02885188 0,07545394 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02885188 0,07537201 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02885188 0,07529026 ! macrophage activation GO:0042116 12 8 0,000 0,02885188 0,07520869 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02885188 0,0751273 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02885188 0,07504608 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02885188 0,07496503 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02885188 0,07488416 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02885188 0,07480347 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02885188 0,07472295 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02885188 0,0746426 ! osteoblast development GO:0002076 16 8 0,000 0,02885188 0,07456243 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02885188 0,07448243 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02885188 0,07440259 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02885188 0,07432293 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02885188 0,07424344 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02885188 0,07416412 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02885188 0,07408497 ! response to UV-B GO:0010224 16 8 0,000 0,02885188 0,07400599 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02885188 0,07392718 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02885188 0,07384853 ! intermediate filament organization GO:0045109 12 8 0,000 0,02885188 0,07377005 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02885188 0,07369174 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02885188 0,0736136 ! cellular extravasation GO:0045123 12 8 0,000 0,02885188 0,07353562 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02885188 0,0734578 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02885188 0,07338015 ! response to antibiotic GO:0046677 11 8 0,000 0,02885188 0,07330266 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02885188 0,07322534 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02885188 0,07314818 ! DNA topological change GO:0006265 12 8 0,000 0,02885188 0,07307118 ! response to tropane GO:0014073 15 8 0,000 0,02885188 0,07299434 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02885188 0,07291767 ! melanosome transport GO:0032402 13 8 0,000 0,02885188 0,07284116 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02885188 0,0727648 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02885188 0,07268861 ! mast cell activation GO:0045576 14 8 0,000 0,02885188 0,07261257 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02885188 0,0725367 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02885188 0,07246098 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02885188 0,07238542 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02885188 0,07231002 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02885188 0,07223478 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02885188 0,07215969 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02885188 0,07208476 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02885188 0,07200998 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02885188 0,07193536 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02885188 0,07186089 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02885188 0,07178658 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02885188 0,07171242 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02885188 0,07163841 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02885188 0,07156456 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02885188 0,07149086 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02885188 0,07141731 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02885188 0,07134391 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02885188 0,07127066 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02885188 0,07119756 ! hormone catabolic process GO:0042447 17 8 0,000 0,02885188 0,07112461 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02885188 0,07105181 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02885188 0,07097916 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02885188 0,07090666 ! ATP catabolic process GO:0006200 11 8 0,000 0,02885188 0,07083431 ! blastocyst growth GO:0001832 19 8 0,000 0,02885188 0,0707621 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02885188 0,07069004 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02885188 0,07061813 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02885188 0,07054636 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02885188 0,07047474 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02885188 0,07040327 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02885188 0,07033194 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02885188 0,07026075 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02885188 0,07018971 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02885188 0,07011881 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02885188 0,07004805 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02885188 0,06997744 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02885188 0,06990697 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02885188 0,06983664 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02885188 0,06976645 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02885188 0,06969641 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02885188 0,0696265 ! learning or memory GO:0007611 147 73 1,000 0,02935939 0,07078025 ! axon guidance GO:0007411 139 73 1,000 0,02935939 0,0707094 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03010422 0,07243076 GO:0090046|regulation of transcription regulator activity, ! neurotransmitter transport GO:0006836 123 74 1,000 0,03010422 0,0723584 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,03085655 0,07409266 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,03085655 0,07401879 ! regulation of catabolic process GO:0009894 161 76 1,000 0,03161629 0,07576574 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,0323834 0,07752684 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03239986 0,07748914 ! axon extension GO:0048675 15 9 0,000 0,03239986 0,07741219 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03239986 0,07733539 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03239986 0,07725875 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03239986 0,07718225 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03239986 0,07710591 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03239986 0,07702972 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03239986 0,07695368 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03239986 0,07687778 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03239986 0,07680204 ! phosphate transport GO:0006817 19 9 0,000 0,03239986 0,07672645 ! reproductive behavior GO:0019098 19 9 0,000 0,03239986 0,07665101 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03239986 0,07657571 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03239986 0,07650056 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03239986 0,07642556 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03239986 0,07635071 ! GTP metabolic process GO:0046039 9 9 0,000 0,03239986 0,076276 ! RNA methylation GO:0001510 15 9 0,000 0,03239986 0,07620144 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03239986 0,07612703 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03239986 0,07605275 ! artery development GO:0060840 24 9 0,000 0,03239986 0,07597863 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03239986 0,07590465 ! regulation of glycolysis GO:0006110 21 9 0,000 0,03239986 0,07583081 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03239986 0,07575712 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03239986 0,07568357 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03239986 0,07561016 ! chemosensory behavior GO:0007635 20 9 0,000 0,03239986 0,07553689 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03239986 0,07546377 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03239986 0,07539079 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03239986 0,07531795 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03239986 0,07524524 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03239986 0,07517268 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03239986 0,07510026 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03239986 0,07502798 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03239986 0,07495584 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03239986 0,07488384 ! protein targeting to ER GO:0045047 22 9 0,000 0,03239986 0,07481197 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03239986 0,07474024 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03239986 0,07466865 ! T cell selection GO:0045058 23 9 0,000 0,03239986 0,0745972 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03239986 0,07452588 ! endosome organization GO:0007032 17 9 0,000 0,03239986 0,0744547 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03239986 0,07438366 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03239986 0,07431275 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03239986 0,07424198 ! mannose metabolic process GO:0006013 13 9 0,000 0,03239986 0,07417134 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03239986 0,07410083 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03239986 0,07403046 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03239986 0,07396022 ! receptor clustering GO:0043113 18 9 0,000 0,03239986 0,07389012 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03239986 0,07382015 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03239986 0,07375031 ! ruffle organization GO:0031529 15 9 0,000 0,03239986 0,0736806 ! retinol metabolic process GO:0042572 18 9 0,000 0,03239986 0,07361102 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03239986 0,07354158 ! behavioral fear response GO:0001662 22 9 0,000 0,03239986 0,07347227 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03239986 0,07340308 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03239986 0,07333403 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03239986 0,07326511 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,03239986 0,07319631 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03239986 0,07312765 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03239986 0,07305911 ! segment specification GO:0007379 13 9 0,000 0,03239986 0,07299071 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03239986 0,07292243 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03239986 0,07285427 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03239986 0,07278625 ! response to amine stimulus GO:0014075 13 9 0,000 0,03239986 0,07271835 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03239986 0,07265058 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03239986 0,07258294 ! erythrocyte development GO:0048821 15 9 0,000 0,03239986 0,07251542 ! gas homeostasis GO:0033483 16 9 0,000 0,03239986 0,07244802 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03239986 0,07238076 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03239986 0,07231361 ! renal water homeostasis GO:0003091 14 9 0,000 0,03239986 0,07224659 ! postreplication repair GO:0006301 22 9 0,000 0,03239986 0,0721797 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03239986 0,07211293 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03239986 0,07204628 ! icosanoid secretion GO:0032309 15 9 0,000 0,03239986 0,07197975 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03239986 0,07191335 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03239986 0,07184707 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03239986 0,07178092 ! regulation of cell division GO:0051302 15 9 0,000 0,03239986 0,07171488 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03239986 0,07164896 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03239986 0,07158317 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03239986 0,0715175 ! sterol catabolic process GO:0016127 11 9 0,000 0,03239986 0,07145195 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03239986 0,07138651 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03239986 0,0713212 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03239986 0,07125601 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03239986 0,07119093 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03239986 0,07112598 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03239986 0,07106114 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03239986 0,07099642 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03239986 0,07093182 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03239986 0,07086734 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03239986 0,07080297 ! purine base metabolic process GO:0006144 21 9 0,000 0,03239986 0,07073872 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03239986 0,07067459 ! pigment granule transport GO:0051904 17 9 0,000 0,03239986 0,07061057 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03239986 0,07054667 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03239986 0,07048289 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03239986 0,07041922 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03239986 0,07035566 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03239986 0,07029222 ! mitochondrion localization GO:0051646 15 9 0,000 0,03239986 0,0702289 ! response to metal ion GO:0010038 140 80 1,000 0,03472828 0,07520814 ! protein import into nucleus GO:0006606 158 80 1,000 0,03472828 0,07514051 ! nuclear import GO:0051170 161 81 1,000 0,03552422 0,07679359 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03593501 0,07761187 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03593501 0,07754226 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03593501 0,07747278 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03593501 0,07740342 ! synapsis GO:0007129 13 10 0,000 0,03593501 0,07733419 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03593501 0,07726508 ! N-glycan processing GO:0006491 20 10 0,000 0,03593501 0,07719609 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03593501 0,07712723 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03593501 0,07705849 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03593501 0,07698987 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03593501 0,07692137 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03593501 0,076853 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03593501 0,07678474 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03593501 0,07671661 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03593501 0,0766486 ! androgen metabolic process GO:0008209 17 10 0,000 0,03593501 0,07658071 ! phospholipid efflux GO:0033700 16 10 0,000 0,03593501 0,07651294 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03593501 0,07644529 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03593501 0,07637776 ! pathogenesis GO:0009405 13 10 0,000 0,03593501 0,07631035 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03593501 0,07624305 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03593501 0,07617588 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03593501 0,07610882 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03593501 0,07604188 ! endoderm development GO:0007492 16 10 0,000 0,03593501 0,07597506 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03593501 0,07590836 ! arginine catabolic process GO:0006527 13 10 0,000 0,03593501 0,07584177 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03593501 0,0757753 ! proline metabolic process GO:0006560 13 10 0,000 0,03593501 0,07570895 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03593501 0,07564271 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03593501 0,07557659 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03593501 0,07551059 ! V(D)J recombination GO:0033151 28 10 0,000 0,03593501 0,0754447 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03593501 0,07537892 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03593501 0,07531326 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03593501 0,07524771 ! B cell proliferation GO:0042100 18 10 0,000 0,03593501 0,07518228 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03593501 0,07511696 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03593501 0,07505176 ! multicellular organism growth GO:0035264 18 10 0,000 0,03593501 0,07498666 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03593501 0,07492168 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03593501 0,07485682 ! epithelial cell development GO:0002064 20 10 0,000 0,03593501 0,07479206 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03593501 0,07472742 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03593501 0,07466289 ! macroautophagy GO:0016236 17 10 0,000 0,03593501 0,07459847 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03593501 0,07453416 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03593501 0,07446996 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03593501 0,07440587 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03593501 0,07434189 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03593501 0,07427803 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03593501 0,07421427 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03593501 0,07415062 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03593501 0,07408708 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03593501 0,07402365 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03593501 0,07396033 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03593501 0,07389711 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03593501 0,07383401 ! response to dsRNA GO:0043331 20 10 0,000 0,03593501 0,07377101 ! DNA ligation GO:0006266 19 10 0,000 0,03593501 0,07370812 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03593501 0,07364533 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03593501 0,07358266 ! melanosome localization GO:0032400 16 10 0,000 0,03593501 0,07352009 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03593501 0,07345762 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03593501 0,07339527 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03593501 0,07333301 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03593501 0,07327087 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03593501 0,07320882 ! mRNA cleavage GO:0006379 17 10 0,000 0,03593501 0,07314689 ! protein sumoylation GO:0016925 15 10 0,000 0,03593501 0,07308506 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03593501 0,07302333 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03593501 0,07296171 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03593501 0,07290019 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03593501 0,07283877 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03593501 0,07277746 ! salivary gland development GO:0007431 27 10 0,000 0,03593501 0,07271625 ! prophase GO:0051324 15 10 0,000 0,03593501 0,07265514 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03593501 0,07259414 ! apical protein localization GO:0045176 15 10 0,000 0,03593501 0,07253324 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03593501 0,07247244 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03593501 0,07241174 ! midbrain development GO:0030901 13 10 0,000 0,03593501 0,07235115 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03593501 0,07229065 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03593501 0,07223026 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03593501 0,07216997 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03593501 0,07210978 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03593501 0,07204969 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03593501 0,07198969 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03593501 0,0719298 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,03593501 0,07187001 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 0,000 0,03593501 0,07181032 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03593501 0,07175072 ! blastocyst formation GO:0001825 17 10 0,000 0,03593501 0,07169123 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03593501 0,07163183 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03593501 0,07157253 ! activation of innate immune response GO:0002218 12 10 0,000 0,03593501 0,07151334 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03593501 0,07145423 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03593501 0,07139523 ! response to nicotine GO:0035094 20 10 0,000 0,03593501 0,07133632 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03593501 0,07127751 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03593501 0,0712188 ! response to drug GO:0042493 143 82 1,000 0,0363272 0,07193683 ! negative regulation of transport GO:0051051 153 84 1,000 0,03795408 0,07509665 ! response to unfolded protein GO:0006986 131 85 1,000 0,03877786 0,07666354 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,03877786 0,0766006 GO:0002696|positive regulation of leukocyte activation, ! respiratory burst GO:0045730 17 11 0,000 0,03945735 0,0778789 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03945735 0,07781506 ! neuron fate specification GO:0048665 17 11 0,000 0,03945735 0,07775133 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03945735 0,07768771 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03945735 0,07762418 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03945735 0,07756077 ! thyroid gland development GO:0030878 26 11 0,000 0,03945735 0,07749745 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03945735 0,07743424 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03945735 0,07737113 ! response to pain GO:0048265 24 11 0,000 0,03945735 0,07730812 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03945735 0,07724522 ! T cell proliferation GO:0042098 26 11 0,000 0,03945735 0,07718242 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03945735 0,07711972 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03945735 0,07705712 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03945735 0,07699463 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03945735 0,07693223 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03945735 0,07686994 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03945735 0,07680775 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03945735 0,07674566 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03945735 0,07668366 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03945735 0,07662177 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03945735 0,07655998 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03945735 0,07649829 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03945735 0,0764367 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03945735 0,0763752 ! UV protection GO:0009650 19 11 0,000 0,03945735 0,07631381 ! adult heart development GO:0007512 14 11 0,000 0,03945735 0,07625251 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03945735 0,07619131 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03945735 0,07613021 ! temperature homeostasis GO:0001659 17 11 0,000 0,03945735 0,07606921 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03945735 0,07600831 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03945735 0,0759475 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03945735 0,07588679 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03945735 0,07582618 ! regulation of organ growth GO:0046620 13 11 0,000 0,03945735 0,07576566 ! pigment granule localization GO:0051875 20 11 0,000 0,03945735 0,07570524 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03945735 0,07564492 ! vasoconstriction GO:0042310 18 11 0,000 0,03945735 0,0755847 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03945735 0,07552456 ! embryonic axis specification GO:0000578 18 11 0,000 0,03945735 0,07546453 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03945735 0,07540459 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03945735 0,07534474 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03945735 0,07528499 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03945735 0,07522534 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03945735 0,07516578 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03945735 0,07510631 ! zymogen activation GO:0031638 15 11 0,000 0,03945735 0,07504694 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03945735 0,07498766 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03945735 0,07492847 ! nucleosome positioning GO:0016584 15 11 0,000 0,03945735 0,07486938 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03945735 0,07481038 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03945735 0,07475148 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03945735 0,07469266 ! acid secretion GO:0046717 18 11 0,000 0,03945735 0,07463394 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03945735 0,07457532 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03945735 0,07451678 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03945735 0,07445833 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03945735 0,07439998 ! oocyte differentiation GO:0009994 18 11 0,000 0,03945735 0,07434172 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03945735 0,07428355 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03945735 0,07422547 ! cholesterol efflux GO:0033344 19 11 0,000 0,03945735 0,07416748 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03945735 0,07410958 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03945735 0,07405178 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03945735 0,07399406 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03945735 0,07393643 ! embryonic gut development GO:0048566 15 11 0,000 0,03945735 0,07387889 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03945735 0,07382144 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03945735 0,07376408 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03945735 0,07370681 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03945735 0,07364963 ! defense response to fungus GO:0050832 13 11 0,000 0,03945735 0,07359254 ! developmental induction GO:0031128 19 11 0,000 0,03945735 0,07353554 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03945735 0,07347862 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03945735 0,07342179 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03945735 0,07336505 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03945735 0,0733084 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03945735 0,07325183 ! regulation of embryonic development GO:0045995 27 11 0,000 0,03945735 0,07319536 ! nucleus localization GO:0051647 19 11 0,000 0,03945735 0,07313897 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03945735 0,07308266 ! response to inorganic substance GO:0010035 153 86 1,000 0,03960844 0,07330609 ! mitochondrion organization GO:0007005 148 86 1,000 0,03960844 0,07324974 ! protein localization in nucleus GO:0034504 176 87 1,000 0,04044578 0,07474081 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,0412898 0,07624195 ! regulation of DNA binding GO:0051101 155 88 1,000 0,0412898 0,07618348 ! gland development GO:0048732 206 88 1,000 0,0412898 0,0761251 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,04214045 0,07763394 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,04214045 0,07757454 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04296694 0,07903551 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04296694 0,07897513 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04296694 0,07891485 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,04296694 0,07885465 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04296694 0,07879455 ! virus-host interaction GO:0019048 29 12 0,000 0,04296694 0,07873454 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04296694 0,07867462 ! cartilage condensation GO:0001502 20 12 0,000 0,04296694 0,07861479 ! mating GO:0007618 17 12 0,000 0,04296694 0,07855505 ! protein complex disassembly GO:0043241 27 12 0,000 0,04296694 0,07849541 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04296694 0,07843585 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,04296694 0,07837638 ! hippocampus development GO:0021766 26 12 0,000 0,04296694 0,07831701 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04296694 0,07825772 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04296694 0,07819852 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04296694 0,07813942 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04296694 0,0780804 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04296694 0,07802147 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04296694 0,07796263 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04296694 0,07790388 ! drug transport GO:0015893 16 12 0,000 0,04296694 0,07784522 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04296694 0,07778664 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04296694 0,07772816 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04296694 0,07766976 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04296694 0,07761145 ! focal adhesion formation GO:0048041 35 12 0,000 0,04296694 0,07755322 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04296694 0,07749509 ! forebrain cell migration GO:0021885 21 12 0,000 0,04296694 0,07743704 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04296694 0,07737908 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04296694 0,0773212 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04296694 0,07726341 ! entry into host cell GO:0030260 32 12 0,000 0,04296694 0,07720571 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,04296694 0,0771481 ! monoamine transport GO:0015844 18 12 0,000 0,04296694 0,07709057 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04296694 0,07703312 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04296694 0,07697576 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04296694 0,07691849 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04296694 0,0768613 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04296694 0,0768042 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04296694 0,07674718 ! protein homotetramerization GO:0051289 21 12 0,000 0,04296694 0,07669024 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04296694 0,07663339 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04296694 0,07657663 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04296694 0,07651995 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04296694 0,07646335 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04296694 0,07640684 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04296694 0,07635041 ! cranial nerve development GO:0021545 20 12 0,000 0,04296694 0,07629406 ! fucose catabolic process GO:0019317 22 12 0,000 0,04296694 0,07623779 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04296694 0,07618161 ! histone methylation GO:0016571 26 12 0,000 0,04296694 0,07612551 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04296694 0,0760695 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04296694 0,07601357 ! gland morphogenesis GO:0022612 29 12 0,000 0,04296694 0,07595771 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04296694 0,07590194 ! T cell homeostasis GO:0043029 25 12 0,000 0,04296694 0,07584626 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04296694 0,07579065 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04296694 0,07573513 ! spleen development GO:0048536 22 12 0,000 0,04296694 0,07567968 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04296694 0,07562432 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04296694 0,07556904 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04296694 0,07551384 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04296694 0,07545872 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04296694 0,07540368 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04296694 0,07534872 ! response to cold GO:0009409 17 12 0,000 0,04296694 0,07529384 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04296694 0,07523905 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04296694 0,07518433 ! ossification GO:0001503 188 90 1,000 0,04299768 0,07518344 ! bone development GO:0060348 189 91 1,000 0,04386142 0,07663804 ! response to protein stimulus GO:0051789 149 91 1,000 0,04386142 0,07658242 ! regulation of membrane potential GO:0042391 164 93 1,000 0,04560821 0,07957459 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,04560821 0,07951692 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04646382 0,08095 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04646382 0,08089142 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04646382 0,08083293 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04646382 0,08077453 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04646382 0,08071621 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04646382 0,08065797 ! lipid localization GO:0010876 28 13 0,000 0,04646382 0,08059982 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04646382 0,08054175 ! organelle fusion GO:0048284 32 13 0,000 0,04646382 0,08048376 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04646382 0,08042586 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04646382 0,08036804 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04646382 0,08031031 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04646382 0,08025265 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04646382 0,08019508 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04646382 0,0801376 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04646382 0,08008019 ! methionine metabolic process GO:0006555 27 13 0,000 0,04646382 0,08002287 ! plasma membrane organization GO:0007009 24 13 0,000 0,04646382 0,07996563 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04646382 0,07990847 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04646382 0,07985139 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04646382 0,07979439 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04646382 0,07973748 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04646382 0,07968065 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04646382 0,07962389 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04646382 0,07956722 ! exocrine system development GO:0035272 32 13 0,000 0,04646382 0,07951063 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,04646382 0,07945412 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04646382 0,07939769 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04646382 0,07934134 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04646382 0,07928507 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04646382 0,07922888 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04646382 0,07917277 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04646382 0,07911674 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04646382 0,07906078 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04646382 0,07900491 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04646382 0,07894912 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04646382 0,0788934 ! ribosome assembly GO:0042255 17 13 0,000 0,04646382 0,07883776 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04646382 0,0787822 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04646382 0,07872672 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04646382 0,07867132 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04646382 0,078616 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04646382 0,07856075 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04646382 0,07850558 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04646382 0,07845049 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04646382 0,07839547 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04646382 0,07834054 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04646382 0,07828568 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04646382 0,07823089 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04646382 0,07817619 ! embryonic placenta development GO:0001892 23 13 0,000 0,04646382 0,07812156 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04646382 0,078067 ! insulin secretion GO:0030073 23 13 0,000 0,04646382 0,07801252 ! actin filament polymerization GO:0030041 24 13 0,000 0,04646382 0,07795812 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04646382 0,0779038 ! acrosome reaction GO:0007340 18 13 0,000 0,04646382 0,07784955 ! regulation of T cell activation GO:0050863 158 94 1,000 0,04649115 0,07784113 ! detection of stimulus GO:0051606 151 96 1,000 0,04827581 0,08077302 ! protein ubiquitination GO:0016567 217 97 1,000 0,04917743 0,08222438 ! rRNA transcription GO:0009303 25 14 0,000 0,04994804 0,08345485 ! lactation GO:0007595 26 14 0,000 0,04994804 0,08339693 ! reproductive cellular process GO:0048610 20 14 0,000 0,04994804 0,0833391 ! tRNA modification GO:0006400 20 14 0,000 0,04994804 0,08328135 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04994804 0,08322367 ! regulation of S phase GO:0033261 23 14 0,000 0,04994804 0,08316608 ! water transport GO:0006833 21 14 0,000 0,04994804 0,08310856 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04994804 0,08305113 ! non-recombinational repair GO:0000726 25 14 0,000 0,04994804 0,08299377 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04994804 0,0829365 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04994804 0,0828793 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04994804 0,08282218 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04994804 0,08276514 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04994804 0,08270818 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04994804 0,08265129 ! palate development GO:0060021 31 14 0,000 0,04994804 0,08259449 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04994804 0,08253776 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04994804 0,08248111 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04994804 0,08242454 ! arginine metabolic process GO:0006525 17 14 0,000 0,04994804 0,08236805 ! regulation of heart rate GO:0002027 24 14 0,000 0,04994804 0,08231163 ! organic alcohol transport GO:0015850 29 14 0,000 0,04994804 0,08225529 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04994804 0,08219903 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04994804 0,08214284 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04994804 0,08208674 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04994804 0,0820307 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04994804 0,08197475 ! L-amino acid transport GO:0015807 30 14 0,000 0,04994804 0,08191887 ! bone mineralization GO:0030282 17 14 0,000 0,04994804 0,08186307 ! stem cell development GO:0048864 43 14 0,000 0,04994804 0,08180734 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04994804 0,08175169 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04994804 0,08169611 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04994804 0,08164061 ! cerebellum development GO:0021549 21 14 0,000 0,04994804 0,08158519 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04994804 0,08152984 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04994804 0,08147456 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04994804 0,08141936 ! cofactor transport GO:0051181 26 14 0,000 0,04994804 0,08136424 ! NADP metabolic process GO:0006739 24 14 0,000 0,04994804 0,08130919 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04994804 0,08125421 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04994804 0,08119931 ! intestinal absorption GO:0050892 25 14 0,000 0,04994804 0,08114448 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04994804 0,08108973 ! oxygen transport GO:0015671 21 14 0,000 0,04994804 0,08103505 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04994804 0,08098045 ! male genitalia development GO:0030539 24 14 0,000 0,04994804 0,08092591 ! regulation of axon extension GO:0030516 37 14 0,000 0,04994804 0,08087145 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04994804 0,08081707 ! response to virus GO:0009615 160 98 1,000 0,05008516 0,08098447 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05341964 0,08631811 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05341964 0,08626018 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05341964 0,08620232 ! superoxide anion generation GO:0042554 20 15 0,000 0,05341964 0,08614455 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05341964 0,08608685 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05341964 0,08602923 ! copper ion transport GO:0006825 20 15 0,000 0,05341964 0,08597168 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05341964 0,08591421 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05341964 0,08585682 ! sulfate transport GO:0008272 23 15 0,000 0,05341964 0,08579951 ! response to cAMP GO:0051591 22 15 0,000 0,05341964 0,08574227 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05341964 0,08568511 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05341964 0,08562802 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05341964 0,08557101 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05341964 0,08551408 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05341964 0,08545722 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05341964 0,08540044 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05341964 0,08534373 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05341964 0,0852871 ! pituitary gland development GO:0021983 29 15 0,000 0,05341964 0,08523055 ! vesicle coating GO:0006901 33 15 0,000 0,05341964 0,08517406 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05341964 0,08511766 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05341964 0,08506133 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05341964 0,08500507 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05341964 0,08494888 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05341964 0,08489278 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05341964 0,08483674 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05341964 0,08478078 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05341964 0,08472489 ! tissue regeneration GO:0042246 26 15 0,000 0,05341964 0,08466908 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05341964 0,08461334 ! water homeostasis GO:0030104 27 15 0,000 0,05341964 0,08455767 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05341964 0,08450208 ! muscle maintenance GO:0046716 26 15 0,000 0,05341964 0,08444656 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05341964 0,08439111 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05341964 0,08433574 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05341964 0,08428043 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05341964 0,0842252 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05341964 0,08417005 ! cell killing GO:0001906 29 15 0,000 0,05341964 0,08411496 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05341964 0,08405995 ! detection of bacterium GO:0016045 18 15 0,000 0,05341964 0,08400501 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05341964 0,08395014 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05341964 0,08389534 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05341964 0,08384062 ! peptide hormone processing GO:0016486 23 15 0,000 0,05341964 0,08378596 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05687868 0,08915316 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,05687868 0,08909512 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05687868 0,08903715 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05687868 0,08897926 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05687868 0,08892144 ! bone remodeling GO:0046849 27 16 0,000 0,05687868 0,0888637 ! filopodium assembly GO:0046847 32 16 0,000 0,05687868 0,08880603 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05687868 0,08874844 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05687868 0,08869093 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05687868 0,08863348 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05687868 0,08857612 ! startle response GO:0001964 28 16 0,000 0,05687868 0,08851882 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05687868 0,0884616 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05687868 0,08840446 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05687868 0,08834738 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05687868 0,08829039 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05687868 0,08823346 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05687868 0,08817661 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05687868 0,08811983 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05687868 0,08806313 ! response to osmotic stress GO:0006970 25 16 0,000 0,05687868 0,08800649 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,05687868 0,08794993 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,05687868 0,08789345 ! fructose metabolic process GO:0006000 25 16 0,000 0,05687868 0,08783703 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05687868 0,08778069 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05687868 0,08772442 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05687868 0,08766822 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05687868 0,0876121 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05687868 0,08755605 ! axon cargo transport GO:0008088 43 16 0,000 0,05687868 0,08750006 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05687868 0,08744415 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05687868 0,08738831 ! DNA replication initiation GO:0006270 27 16 0,000 0,05687868 0,08733255 ! neuron recognition GO:0008038 35 16 0,000 0,05687868 0,08727685 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05687868 0,08722122 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05687868 0,08716567 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05687868 0,08711018 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05687868 0,08705477 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05687868 0,08699943 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05687868 0,08694415 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05687868 0,08688895 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05687868 0,08683382 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05687868 0,08677876 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05687868 0,08672376 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06032519 0,09192045 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06032519 0,09186228 ! metencephalon development GO:0022037 30 17 0,000 0,06032519 0,09180417 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06032519 0,09174614 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06032519 0,09168819 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06032519 0,0916303 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06032519 0,09157249 ! signal complex assembly GO:0007172 41 17 0,000 0,06032519 0,09151475 ! endothelial cell migration GO:0043542 28 17 0,000 0,06032519 0,09145709 ! inositol metabolic process GO:0006020 28 17 0,000 0,06032519 0,09139949 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06032519 0,09134197 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06032519 0,09128453 ! glial cell development GO:0021782 27 17 0,000 0,06032519 0,09122715 ! limbic system development GO:0021761 36 17 0,000 0,06032519 0,09116985 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06032519 0,09111262 ! adult walking behavior GO:0007628 33 17 0,000 0,06032519 0,09105546 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06032519 0,09099837 ! heart looping GO:0001947 30 17 0,000 0,06032519 0,09094135 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06032519 0,09088441 ! myoblast differentiation GO:0045445 45 17 0,000 0,06032519 0,09082753 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06032519 0,09077073 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,06032519 0,090714 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06032519 0,09065734 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06032519 0,09060075 ! glycine metabolic process GO:0006544 28 17 0,000 0,06032519 0,09054423 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06032519 0,09048778 ! NAD metabolic process GO:0019674 29 17 0,000 0,06032519 0,0904314 ! membrane budding GO:0006900 37 17 0,000 0,06032519 0,09037509 ! DNA integration GO:0015074 29 17 0,000 0,06032519 0,09031885 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06032519 0,09026268 ! regulation of protein binding GO:0043393 33 17 0,000 0,06032519 0,09020659 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06032519 0,09015056 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06032519 0,0900946 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06032519 0,09003871 ! genitalia development GO:0048806 30 17 0,000 0,06032519 0,08998289 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,06032519 0,08992714 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06032519 0,08987145 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06032519 0,08981584 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06032519 0,0897603 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06032519 0,08970482 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06032519 0,08964941 ! steroid catabolic process GO:0006706 31 17 0,000 0,06032519 0,08959407 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06032519 0,0895388 ! gas transport GO:0015669 25 17 0,000 0,06032519 0,0894836 ! organic cation transport GO:0015695 31 17 0,000 0,06032519 0,08942846 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06032519 0,0893734 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06032519 0,0893184 ! microspike assembly GO:0030035 36 17 0,000 0,06032519 0,08926347 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06032519 0,0892086 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06032519 0,08915381 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06375921 0,09417107 ! neuron maturation GO:0042551 42 18 0,000 0,06375921 0,09411329 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06375921 0,09405559 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06375921 0,09399796 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06375921 0,0939404 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06375921 0,09388291 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06375921 0,09382548 ! memory GO:0007613 31 18 0,000 0,06375921 0,09376813 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06375921 0,09371085 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06375921 0,09365364 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06375921 0,0935965 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06375921 0,09353943 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06375921 0,09348243 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06375921 0,0934255 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06375921 0,09336864 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06375921 0,09331184 ! response to retinoic acid GO:0032526 26 18 0,000 0,06375921 0,09325512 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,06375921 0,09319846 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,06375921 0,09314187 ! response to fungus GO:0009620 21 18 0,000 0,06375921 0,09308536 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06375921 0,09302891 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06375921 0,09297253 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06375921 0,09291621 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06375921 0,09285997 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06375921 0,09280379 ! vitamin transport GO:0051180 27 18 0,000 0,06375921 0,09274768 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06375921 0,09269164 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06375921 0,09263567 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06375921 0,09257976 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06375921 0,09252392 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,06375921 0,09246815 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06375921 0,09241245 ! nerve development GO:0021675 28 18 0,000 0,06375921 0,09235681 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06375921 0,09230124 ! protein secretion GO:0009306 39 19 0,000 0,06718081 0,09719604 ! positive regulation of translation GO:0045727 30 19 0,000 0,06718081 0,09713763 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06718081 0,09707929 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,06718081 0,09702102 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,06718081 0,09696282 ! skin development GO:0043588 36 19 0,000 0,06718081 0,09690469 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,06718081 0,09684662 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06718081 0,09678863 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,06718081 0,09673071 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06718081 0,09667286 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06718081 0,09661507 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06718081 0,09655736 ! cerebral cortex development GO:0021987 36 19 0,000 0,06718081 0,09649971 ! pigmentation during development GO:0048066 41 19 0,000 0,06718081 0,09644213 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,06718081 0,09638463 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,06718081 0,09632719 ! heme metabolic process GO:0042168 36 19 0,000 0,06718081 0,09626981 ! actin filament bundle formation GO:0051017 42 19 0,000 0,06718081 0,09621251 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,06718081 0,09615527 ! plasma membrane fusion GO:0045026 28 19 0,000 0,06718081 0,09609811 ! peptide cross-linking GO:0018149 37 19 0,000 0,06718081 0,09604101 ! protein export from nucleus GO:0006611 36 19 0,000 0,06718081 0,09598398 ! heart process GO:0003015 30 19 0,000 0,06718081 0,09592701 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06718081 0,09587012 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,06718081 0,09581329 ! visual learning GO:0008542 36 19 0,000 0,06718081 0,09575653 ! cellular pigmentation GO:0033059 36 19 0,000 0,06718081 0,09569983 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,06718081 0,09564321 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06718081 0,09558665 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,06718081 0,09553015 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06718081 0,09547373 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06718081 0,09541737 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,06718081 0,09536107 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06718081 0,09530484 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,06718081 0,09524868 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06718081 0,09519259 ! cilium assembly GO:0042384 37 19 0,000 0,06718081 0,09513656 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06718081 0,0950806 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,07059001 0,09984689 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,07059001 0,09978822 ! positive regulation of ossification GO:0045778 47 20 0,000 0,07059001 0,09972963 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,07059001 0,0996711 ! cAMP metabolic process GO:0046058 36 20 0,000 0,07059001 0,09961264 ! response to vitamin GO:0033273 31 20 0,000 0,07059001 0,09955425 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,07059001 0,09949593 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,07059001 0,09943768 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,07059001 0,09937949 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,07059001 0,09932138 ! response to alkaloid GO:0043279 38 20 0,000 0,07059001 0,09926333 ! retinoid metabolic process GO:0001523 32 20 0,000 0,07059001 0,09920535 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,07059001 0,09914743 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,07059001 0,09908959 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,07059001 0,09903181 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,07059001 0,0989741 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,07059001 0,09891645 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,07059001 0,09885888 ! body fluid secretion GO:0007589 31 20 0,000 0,07059001 0,09880137 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,07059001 0,09874393 ! peptide secretion GO:0002790 35 20 0,000 0,07059001 0,09868655 ! stem cell differentiation GO:0048863 53 20 0,000 0,07059001 0,09862924 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,07059001 0,098572 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,07059001 0,09851482 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,07059001 0,09845771 ! sensory perception of pain GO:0019233 30 20 0,000 0,07059001 0,09840067 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,07059001 0,09834369 ! diencephalon development GO:0021536 34 20 0,000 0,07059001 0,09828678 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,07059001 0,09822993 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,07059001 0,09817315 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,07059001 0,09811644 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,07059001 0,09805979 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,07059001 0,0980032 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,07059001 0,09794669 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,07059001 0,09789023 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,07059001 0,09783384 ! regulation of glucose import GO:0046324 29 20 0,000 0,07059001 0,09777752 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,07059001 0,09772126 ! actin filament-based movement GO:0030048 43 20 0,000 0,07059001 0,09766507 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,07059001 0,09760894 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,07059001 0,09755287 ! negative regulation of translation GO:0017148 29 20 0,000 0,07059001 0,09749687 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,07059001 0,09744094 ! regulation of cell killing GO:0031341 42 21 0,000 0,07398686 0,10207132 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,07398686 0,10201283 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,07398686 0,1019544 ! hormone secretion GO:0046879 38 21 0,000 0,07398686 0,10189604 ! glycerol metabolic process GO:0006071 34 21 0,000 0,07398686 0,10183775 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,07398686 0,10177952 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,07398686 0,10172136 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,07398686 0,10166327 ! axis specification GO:0009798 38 21 0,000 0,07398686 0,10160524 ! ovarian follicle development GO:0001541 35 21 0,000 0,07398686 0,10154728 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,07398686 0,10148939 ! smooth muscle contraction GO:0006939 46 21 0,000 0,07398686 0,10143156 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,07398686 0,10137379 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,07398686 0,1013161 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,07398686 0,10125847 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,07398686 0,1012009 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,07398686 0,1011434 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,07398686 0,10108596 ! cytolysis GO:0019835 24 21 0,000 0,07398686 0,10102859 ! vasodilation GO:0042311 39 21 0,000 0,07398686 0,10097129 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,07398686 0,10091405 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,07398686 0,10085687 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,07398686 0,10079976 ! oogenesis GO:0048477 36 21 0,000 0,07398686 0,10074272 ! DNA modification GO:0006304 34 21 0,000 0,07398686 0,10068574 ! collagen fibril organization GO:0030199 59 21 0,000 0,07398686 0,10062882 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,07398686 0,10057197 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,07398686 0,10051518 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,07398686 0,10045846 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,07398686 0,1004018 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,07398686 0,1003452 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,07398686 0,10028867 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,07398686 0,1002322 ! collagen catabolic process GO:0030574 28 21 0,000 0,07398686 0,10017579 ! sperm-egg recognition GO:0035036 21 21 0,000 0,07398686 0,10011945 ! gut development GO:0048565 39 21 0,000 0,07398686 0,10006317 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07737141 0,1045818 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07737141 0,10452308 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,07737141 0,10446443 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,07737141 0,10440584 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07737141 0,10434732 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07737141 0,10428886 ! regeneration GO:0031099 41 22 0,000 0,07737141 0,10423047 ! keratinization GO:0031424 28 22 0,000 0,07737141 0,10417214 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,07737141 0,10411388 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07737141 0,10405568 ! sensory perception of taste GO:0050909 28 22 0,000 0,07737141 0,10399755 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07737141 0,10393948 ! vacuolar transport GO:0007034 36 22 0,000 0,07737141 0,10388148 ! lysosome organization GO:0007040 41 22 0,000 0,07737141 0,10382354 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07737141 0,10376567 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,07737141 0,10370786 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,07737141 0,10365012 ! fucose metabolic process GO:0006004 39 22 0,000 0,07737141 0,10359244 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07737141 0,10353482 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,07737141 0,10347727 ! ureteric bud development GO:0001657 43 22 0,000 0,07737141 0,10341978 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,07737141 0,10336236 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,07737141 0,103305 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,07737141 0,10324771 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07737141 0,10319047 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07737141 0,1031333 ! sarcomere organization GO:0045214 30 22 0,000 0,07737141 0,1030762 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,07737141 0,10301915 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,07737141 0,10296217 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07737141 0,10290526 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,07737141 0,1028484 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,07737141 0,10279161 ! protein stabilization GO:0050821 39 22 0,000 0,07737141 0,10273489 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,0807437 0,10715353 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,0807437 0,10709446 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0807437 0,10703545 ! gluconeogenesis GO:0006094 33 23 0,000 0,0807437 0,10697651 ! viral genome replication GO:0019079 41 23 0,000 0,0807437 0,10691764 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0807437 0,10685883 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0807437 0,10680008 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0807437 0,1067414 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0807437 0,10668278 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0807437 0,10662423 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0807437 0,10656574 ! visual behavior GO:0007632 42 23 0,000 0,0807437 0,10650732 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0807437 0,10644896 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0807437 0,10639066 ! response to ethanol GO:0045471 46 23 0,000 0,0807437 0,10633243 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0807437 0,10627426 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,0807437 0,10621616 ! peroxisome organization GO:0007031 37 23 0,000 0,0807437 0,10615811 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0807437 0,10610014 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0807437 0,10604222 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0807437 0,10598437 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0807437 0,10592658 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,0807437 0,10586885 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0807437 0,10581119 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0807437 0,10575359 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0807437 0,10569605 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0807437 0,10563858 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0807437 0,10558117 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0807437 0,10552382 ! fatty acid transport GO:0015908 44 23 0,000 0,0807437 0,10546653 ! platelet activation GO:0030168 37 23 0,000 0,0807437 0,1054093 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0807437 0,10535214 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0807437 0,10529504 ! hormone transport GO:0009914 40 23 0,000 0,0807437 0,105238 ! cell-cell recognition GO:0009988 25 23 0,000 0,0807437 0,10518102 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0807437 0,10512411 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0807437 0,10506725 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0807437 0,10501046 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0807437 0,10495373 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0807437 0,10489706 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,08410378 0,10920329 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,08410378 0,10914439 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,08410378 0,10908555 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,08410378 0,10902678 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,08410378 0,10896806 ! vesicle docking GO:0048278 47 24 0,000 0,08410378 0,10890942 ! spinal cord development GO:0021510 47 24 0,000 0,08410378 0,10885083 ! vacuole organization GO:0007033 43 24 0,000 0,08410378 0,10879231 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,08410378 0,10873385 ! digestive system process GO:0022600 39 24 0,000 0,08410378 0,10867545 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,08410378 0,10861712 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,08410378 0,10855885 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,08410378 0,10850064 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,08410378 0,1084425 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,08410378 0,10838441 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,08410378 0,10832639 ! membrane depolarization GO:0051899 39 24 0,000 0,08410378 0,10826843 ! pallium development GO:0021543 49 24 0,000 0,08410378 0,10821053 ! pentose metabolic process GO:0019321 35 24 0,000 0,08410378 0,1081527 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,08410378 0,10809492 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,08410378 0,10803721 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,08410378 0,10797956 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,08410378 0,10792197 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,08410378 0,10786444 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,08410378 0,10780698 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,08410378 0,10774957 ! regulation of amine transport GO:0051952 40 24 0,000 0,08410378 0,10769223 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,08745169 0,11191955 ! phototransduction GO:0007602 33 25 0,000 0,08745169 0,11186005 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,08745169 0,11180062 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,08745169 0,11174124 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,08745169 0,11168193 ! receptor metabolic process GO:0043112 46 25 0,000 0,08745169 0,11162269 ! chromosome condensation GO:0030261 45 25 0,000 0,08745169 0,1115635 ! osteoblast differentiation GO:0001649 60 25 0,000 0,08745169 0,11150438 ! neural crest cell development GO:0014032 54 25 0,000 0,08745169 0,11144532 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,08745169 0,11138632 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,08745169 0,11132739 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,08745169 0,11126852 ! interaction with host GO:0051701 62 25 0,000 0,08745169 0,11120971 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,08745169 0,11115096 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,08745169 0,11109227 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,08745169 0,11103365 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,08745169 0,11097509 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,08745169 0,11091659 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,08745169 0,11085815 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,08745169 0,11079977 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,08745169 0,11074145 ! telomere organization GO:0032200 43 25 0,000 0,08745169 0,1106832 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,08745169 0,11062501 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,08745169 0,11056687 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09078747 0,11472408 ! embryonic pattern specification GO:0009880 44 26 0,000 0,09078747 0,11466386 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09078747 0,1146037 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09078747 0,1145436 ! initiation of viral infection GO:0019059 57 26 0,000 0,09078747 0,11448357 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09078747 0,1144236 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,09078747 0,11436369 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09078747 0,11430385 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,09078747 0,11424406 ! molting cycle process GO:0022404 50 26 0,000 0,09078747 0,11418434 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,09078747 0,11412469 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09078747 0,11406509 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09078747 0,11400556 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09078747 0,11394609 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09078747 0,11388668 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,09078747 0,11382733 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09078747 0,11376805 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,09078747 0,11370882 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09078747 0,11364966 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,09078747 0,11359056 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09078747 0,11353152 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09078747 0,11347255 ! blastocyst development GO:0001824 49 26 0,000 0,09078747 0,11341363 ! leukocyte proliferation GO:0070661 52 26 0,000 0,09078747 0,11335477 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09078747 0,11329598 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09078747 0,11323725 ! neuron fate commitment GO:0048663 48 27 0,000 0,09411117 0,117322 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,09411117 0,11726125 ! iron ion transport GO:0006826 59 27 0,000 0,09411117 0,11720055 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,09411117 0,11713992 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,09411117 0,11707935 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,09411117 0,11701885 ! fat cell differentiation GO:0045444 50 27 0,000 0,09411117 0,1169584 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,09411117 0,11689802 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,09411117 0,1168377 ! autophagy GO:0006914 41 27 0,000 0,09411117 0,11677745 ! male gonad development GO:0008584 44 27 0,000 0,09411117 0,11671725 ! response to toxin GO:0009636 47 27 0,000 0,09411117 0,11665712 ! primary neural tube formation GO:0014020 51 27 0,000 0,09411117 0,11659705 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,09411117 0,11653704 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,09411117 0,11647709 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,09411117 0,11641721 ! glutathione metabolic process GO:0006749 39 27 0,000 0,09411117 0,11635738 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,09411117 0,11629762 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,09411117 0,11623792 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,09411117 0,11617828 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,09742282 0,12020478 ! circadian rhythm GO:0007623 50 28 0,000 0,09742282 0,12014316 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,09742282 0,12008162 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,09742282 0,12002013 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,09742282 0,11995871 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,09742282 0,11989735 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,09742282 0,11983605 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,09742282 0,11977482 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,09742282 0,11971364 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,09742282 0,11965253 ! synaptogenesis GO:0007416 42 28 0,000 0,09742282 0,11959149 ! lipid oxidation GO:0034440 43 28 0,000 0,09742282 0,1195305 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,09742282 0,11946958 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,09742282 0,11940872 ! translational initiation GO:0006413 65 29 0,000 0,10072248 0,12339017 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,10072248 0,12332738 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10072248 0,12326465 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,10072248 0,12320198 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10072248 0,12313938 ! catechol metabolic process GO:0009712 54 29 0,000 0,10072248 0,12307684 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10072248 0,12301436 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10072248 0,12295195 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,10072248 0,1228896 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,10072248 0,12282732 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,10072248 0,1227651 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,10072248 0,12270294 ! cell fate determination GO:0001709 60 29 0,000 0,10072248 0,12264084 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,10072248 0,12257881 ! detection of light stimulus GO:0009583 38 29 0,000 0,10072248 0,12251683 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,10072248 0,12245493 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,10072248 0,12239308 ! regulation of coagulation GO:0050818 46 29 0,000 0,10072248 0,1223313 ! phenol metabolic process GO:0018958 55 30 0,000 0,10401019 0,12626061 ! zinc ion transport GO:0006829 45 30 0,000 0,10401019 0,12619693 ! membrane docking GO:0022406 61 30 0,000 0,10401019 0,12613333 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,10401019 0,12606978 ! cell junction assembly GO:0034329 78 30 0,000 0,10401019 0,1260063 ! regulation of innate immune response GO:0045088 51 30 0,000 0,10401019 0,12594289 ! acute-phase response GO:0006953 49 30 0,000 0,10401019 0,12587954 ! myofibril assembly GO:0030239 47 30 0,000 0,10401019 0,12581625 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,10401019 0,12575303 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,10401019 0,12568986 ! phospholipid transport GO:0015914 51 30 0,000 0,10401019 0,12562677 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,10401019 0,12556373 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,10401019 0,12550076 ! eye morphogenesis GO:0048592 60 30 0,000 0,10401019 0,12543785 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,10728599 0,12932369 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,10728599 0,12925893 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,10728599 0,12919424 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,10728599 0,12912961 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,10728599 0,12906504 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,10728599 0,12900054 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,10728599 0,12893611 ! ovulation cycle process GO:0022602 49 31 0,000 0,10728599 0,12887174 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,10728599 0,12880743 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,10728599 0,12874319 ! peptide transport GO:0015833 55 31 0,000 0,10728599 0,12867901 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,10728599 0,12861489 ! iron ion homeostasis GO:0055072 54 31 0,000 0,10728599 0,12855084 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,10728599 0,12848685 ! mesoderm formation GO:0001707 69 31 0,000 0,10728599 0,12842293 ! natural killer cell activation GO:0030101 45 31 0,000 0,10728599 0,12835907 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,10728599 0,12829527 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,10728599 0,12823154 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,10728599 0,12816787 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,10728599 0,12810426 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,10728599 0,12804072 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11054992 0,13187065 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,11054992 0,1318053 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,11054992 0,13174002 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,11054992 0,1316748 ! cholesterol transport GO:0030301 56 32 0,000 0,11054992 0,13160965 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11054992 0,13154456 ! spliceosome assembly GO:0000245 67 32 0,000 0,11054992 0,13147953 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,11054992 0,13141457 ! metanephros development GO:0001656 74 32 0,000 0,11054992 0,13134968 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11054992 0,13128485 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,11054992 0,13122008 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11054992 0,13115537 ! muscle cell development GO:0055001 49 32 0,000 0,11054992 0,13109073 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,11054992 0,13102616 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,11054992 0,13096164 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,11054992 0,13089719 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,11054992 0,13083281 ! ovulation cycle GO:0042698 51 32 0,000 0,11054992 0,13076848 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11054992 0,13070422 ! hindbrain development GO:0030902 61 32 0,000 0,11054992 0,13064003 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11054992 0,13057589 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11054992 0,13051182 ! post-embryonic development GO:0009791 69 33 0,000 0,11380202 0,13428527 ! protein targeting to membrane GO:0006612 68 33 0,000 0,11380202 0,13421944 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,11380202 0,13415368 ! ceramide metabolic process GO:0006672 64 33 0,000 0,11380202 0,13408798 ! formation of primary germ layer GO:0001704 72 33 0,000 0,11380202 0,13402235 ! cell fate specification GO:0001708 52 33 0,000 0,11380202 0,13395678 ! sterol transport GO:0015918 57 33 0,000 0,11380202 0,13389127 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,11380202 0,13382583 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,11380202 0,13376046 ! adult locomotory behavior GO:0008344 59 33 0,000 0,11380202 0,13369514 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,11380202 0,1336299 ! glial cell differentiation GO:0010001 63 34 0,000 0,11704234 0,13736774 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,11704234 0,13730076 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,11704234 0,13723385 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,11704234 0,13716701 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,11704234 0,13710023 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,11704234 0,13703351 ! mismatch repair GO:0006298 46 34 0,000 0,11704234 0,13696686 ! spermatid development GO:0007286 63 34 0,000 0,11704234 0,13690027 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,11704234 0,13683375 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,11704234 0,1367673 ! placenta development GO:0001890 53 34 0,000 0,11704234 0,13670091 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,11704234 0,13663458 ! negative regulation of secretion GO:0051048 63 35 0,000 0,12027092 0,14033551 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,12027092 0,14026749 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,12027092 0,14019953 ! odontogenesis GO:0042476 66 35 0,000 0,12027092 0,14013164 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,12027092 0,14006381 ! female gonad development GO:0008585 58 35 0,000 0,12027092 0,13999605 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,12027092 0,13992835 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,12027092 0,13986072 ! cytokine production GO:0001816 59 35 0,000 0,12027092 0,13979315 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,12027092 0,13972565 ! neural tube formation GO:0001841 67 35 0,000 0,12027092 0,13965822 ! vesicle localization GO:0051648 64 35 0,000 0,12027092 0,13959085 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,1234878 0,14325537 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,1234878 0,14318633 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,1234878 0,14311736 ! cell junction organization GO:0034330 86 36 0,000 0,1234878 0,14304846 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,1234878 0,14297962 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,1234878 0,14291084 ! positive regulation of cell development GO:0010720 80 36 0,000 0,1234878 0,14284214 ! regulation of proteolysis GO:0030162 72 36 0,000 0,1234878 0,14277349 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,1234878 0,14270492 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,1234878 0,14263641 ! aerobic respiration GO:0009060 55 36 0,000 0,1234878 0,14256797 ! embryonic organ development GO:0048568 57 36 0,000 0,1234878 0,14249959 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,1234878 0,14243128 ! RNA export from nucleus GO:0006405 56 37 0,000 0,12669302 0,14605817 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,12669302 0,14598822 ! meiosis I GO:0007127 65 37 0,000 0,12669302 0,14591834 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,12669302 0,14584852 ! sister chromatid segregation GO:0000819 58 37 0,000 0,12669302 0,14577877 ! actomyosin structure organization GO:0031032 62 37 0,000 0,12669302 0,14570909 ! organic anion transport GO:0015711 68 37 0,000 0,12669302 0,14563947 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,12669302 0,14556992 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,12669302 0,14550043 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,12669302 0,14543102 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,12669302 0,14536166 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,12669302 0,14529238 ! glycogen metabolic process GO:0005977 61 37 0,000 0,12669302 0,14522316 ! pigment metabolic process GO:0042440 80 37 0,000 0,12669302 0,145154 ! spermatid differentiation GO:0048515 66 37 0,000 0,12669302 0,14508492 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,12988663 0,14867138 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,12988663 0,14860068 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,12988663 0,14853005 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,12988663 0,14845949 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,12988663 0,148389 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,12988663 0,14831857 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,12988663 0,14824821 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,12988663 0,14817792 ! lipid homeostasis GO:0055088 67 38 0,000 0,12988663 0,14810769 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,12988663 0,14803753 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,12988663 0,14796744 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,12988663 0,14789741 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,12988663 0,14782745 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,12988663 0,14775756 ! glucan metabolic process GO:0044042 62 38 0,000 0,12988663 0,14768773 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,13306867 0,15123439 ! learning GO:0007612 77 39 0,000 0,13306867 0,15116299 ! organic ether metabolic process GO:0018904 55 39 0,000 0,13306867 0,15109165 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,13306867 0,15102038 ! ion transmembrane transport GO:0034220 66 39 0,000 0,13306867 0,15094918 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,13306867 0,15087805 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,13306867 0,15080698 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,13306867 0,15073598 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,13623917 0,1542548 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,13623917 0,15418224 ! feeding behavior GO:0007631 59 40 0,000 0,13623917 0,15410975 ! negative regulation of binding GO:0051100 72 40 0,000 0,13623917 0,15403733 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,13623917 0,15396498 ! maintenance of protein location GO:0045185 91 40 0,000 0,13623917 0,1538927 ! cytokinesis GO:0000910 72 40 0,000 0,13623917 0,15382048 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,13939819 0,15731334 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,13939819 0,15723959 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,13939819 0,1571659 ! gliogenesis GO:0042063 88 41 0,000 0,13939819 0,15709229 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,13939819 0,15701874 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,13939819 0,15694527 ! female gamete generation GO:0007292 61 41 0,000 0,13939819 0,15687186 ! polyol metabolic process GO:0019751 66 41 0,000 0,13939819 0,15679852 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,13939819 0,15672525 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,14254575 0,1601892 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,14254575 0,16011442 ! regulation of tube size GO:0035150 71 42 0,000 0,14254575 0,1600397 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,14254575 0,15996506 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,14254575 0,15989048 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,14254575 0,15981597 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,14254575 0,15974154 ! neuron migration GO:0001764 79 42 0,000 0,14254575 0,15966717 ! regulation of protein secretion GO:0050708 71 42 0,000 0,14254575 0,15959287 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,14254575 0,15951864 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,14568191 0,16295243 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,14568191 0,16287671 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,14568191 0,16280106 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,14568191 0,16272548 ! glucose transport GO:0015758 65 43 0,000 0,14568191 0,16264997 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,14568191 0,16257453 ! neural tube development GO:0021915 77 43 0,000 0,14568191 0,16249916 ! striated muscle contraction GO:0006941 77 43 0,000 0,14568191 0,16242386 ! phagocytosis GO:0006909 90 43 0,000 0,14568191 0,16234862 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,14568191 0,16227346 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,1488067 0,16567743 ! hexose transport GO:0008645 67 44 0,000 0,1488067 0,1656008 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,1488067 0,16552424 ! male sex differentiation GO:0046661 76 44 0,000 0,1488067 0,16544775 ! biopolymer methylation GO:0043414 84 44 0,000 0,1488067 0,16537133 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,1488067 0,16529498 ! developmental growth GO:0048589 82 44 0,000 0,1488067 0,1652187 ! maintenance of location in cell GO:0051651 97 44 0,000 0,1488067 0,16514249 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,15192017 0,16852002 ! glycolysis GO:0006096 65 45 0,000 0,15192017 0,16844236 ! leukocyte migration GO:0050900 68 45 0,000 0,15192017 0,16836478 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,15192017 0,16828726 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,15192017 0,16820981 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,15192017 0,16813244 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,15192017 0,16805514 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,15192017 0,16797791 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,15192017 0,16790075 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,15192017 0,16782366 ! cell growth GO:0016049 84 45 0,000 0,15192017 0,16774664 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,15502235 0,17109347 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,15502235 0,17101503 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,15502235 0,17093665 ! pigmentation GO:0043473 100 46 0,000 0,15502235 0,17085835 ! positive regulation of defense response GO:0031349 76 47 0,000 0,15811329 0,17418524 ! endosome transport GO:0016197 108 47 0,000 0,15811329 0,17410552 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,15811329 0,17402588 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,15811329 0,1739463 ! JNK cascade GO:0007254 91 47 0,000 0,15811329 0,1738668 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,15811329 0,17378738 ! methylation GO:0032259 90 47 0,000 0,15811329 0,17370802 ! Notch signaling pathway GO:0007219 96 48 0,000 0,16119302 0,17701068 ! cellular component disassembly GO:0022411 86 48 0,000 0,16119302 0,17692993 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,16119302 0,17684925 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,16119302 0,17676864 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,16119302 0,17668811 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,16119302 0,17660765 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,16119302 0,17652727 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,16426159 0,1798059 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,16426159 0,17972414 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,16426159 0,17964244 ! regulation of ion transport GO:0043269 77 49 0,000 0,16426159 0,17956083 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,16426159 0,17947928 ! peptide metabolic process GO:0006518 76 49 0,000 0,16426159 0,17939781 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,16426159 0,17931641 ! endocrine system development GO:0035270 104 49 0,000 0,16426159 0,17923509 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,16426159 0,17915384 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,16426159 0,17907267 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,16426159 0,17899157 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,16426159 0,17891054 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,16731903 0,18215818 ! neuromuscular process GO:0050905 99 50 0,000 0,16731903 0,1820758 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,16731903 0,18199348 ! viral infectious cycle GO:0019058 99 51 0,000 0,17036539 0,18522328 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,17036539 0,18513962 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,17036539 0,18505604 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,17036539 0,18497253 ! excretion GO:0007588 83 51 0,000 0,17036539 0,1848891 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,17036539 0,18480574 ! vesicle organization GO:0016050 107 51 0,000 0,17036539 0,18472246 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,17036539 0,18463925 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,17340071 0,18784426 ! membrane fusion GO:0006944 110 52 0,000 0,17340071 0,18775972 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,17340071 0,18767526 ! amino acid activation GO:0043038 92 52 0,000 0,17340071 0,18759087 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,17340071 0,18750656 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,17642502 0,19069119 ! RNA catabolic process GO:0006401 93 53 0,000 0,17642502 0,19060556 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,17642502 0,19052001 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,17642502 0,19043454 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,17642502 0,19034914 ! cell maturation GO:0048469 100 53 0,000 0,17642502 0,19026382 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,17642502 0,19017858 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,17943836 0,19334022 ! cell recognition GO:0008037 85 54 0,000 0,17943836 0,19325367 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,17943836 0,19316721 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,17943836 0,19308082 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,17943836 0,1929945 ! chloride transport GO:0006821 90 55 0,000 0,18244078 0,19613607 ! glucose catabolic process GO:0006007 82 55 0,000 0,18244078 0,19604847 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,18244078 0,19596095 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,18244078 0,19587351 ! gastrulation GO:0007369 112 55 0,000 0,18244078 0,19578614 ! heart morphogenesis GO:0003007 97 55 0,000 0,18244078 0,19569885 ! nuclear export GO:0051168 97 55 0,000 0,18244078 0,19561164 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,18244078 0,19552451 ! regulation of actin filament length GO:0030832 105 56 0,000 0,18543232 0,1986421 ! sensory perception of smell GO:0007608 80 56 0,000 0,18543232 0,1985537 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,18543232 0,19846537 ! proton transport GO:0015992 94 56 0,000 0,18543232 0,19837713 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,18543232 0,19828896 ! maintenance of location GO:0051235 118 57 0,000 0,18841301 0,2013868 ! hydrogen transport GO:0006818 97 58 0,000 0,19138289 0,20447035 ! regulation of endocytosis GO:0030100 91 58 0,000 0,19138289 0,20437959 ! adult behavior GO:0030534 99 58 0,000 0,19138289 0,20428892 ! positive regulation of secretion GO:0051047 95 59 0,000 0,194342 0,20735558 ! regulation of cellular component size GO:0032535 109 59 0,000 0,194342 0,20726367 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,194342 0,20717184 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,194342 0,20708009 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,194342 0,20698842 ! DNA catabolic process GO:0006308 86 59 0,000 0,194342 0,20689683 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,194342 0,20680533 ! establishment of organelle localization GO:0051656 109 59 0,000 0,194342 0,2067139 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,19729038 0,20975724 ! regulation of heart contraction GO:0008016 110 60 0,000 0,19729038 0,20966459 ! camera-type eye development GO:0043010 116 60 0,000 0,19729038 0,20957203 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,19729038 0,20947954 ! kidney development GO:0001822 122 60 0,000 0,19729038 0,20938714 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,20022806 0,21241125 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,20022806 0,21231764 ! mesoderm development GO:0007498 119 61 0,000 0,20022806 0,2122241 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,20022806 0,21213066 ! viral reproductive process GO:0022415 126 62 0,000 0,2031551 0,21513695 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,2031551 0,21504231 ! gonad development GO:0008406 98 62 0,000 0,2031551 0,21494774 ! regulation of mitosis GO:0007088 105 63 0,000 0,20607151 0,21793761 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,20607151 0,21784185 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,20607151 0,21774618 ! detection of external stimulus GO:0009581 91 63 0,000 0,20607151 0,2176506 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,20607151 0,21755509 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,20897735 0,2205261 ! cell redox homeostasis GO:0045454 102 64 0,000 0,20897735 0,22042942 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,20897735 0,22033283 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,20897735 0,22023632 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,20897735 0,22013989 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,21187266 0,22309217 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,21187266 0,22299458 ! germ cell development GO:0007281 118 65 0,000 0,21187266 0,22289707 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,21187266 0,22279965 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,21475746 0,22573457 ! actin filament organization GO:0007015 148 66 0,000 0,21475746 0,225636 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,21475746 0,22553751 ! extracellular matrix organization GO:0030198 133 66 0,000 0,21475746 0,22543911 ! secondary metabolic process GO:0019748 116 66 0,000 0,21475746 0,22534079 ! developmental maturation GO:0021700 116 66 0,000 0,21475746 0,22524256 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,21763179 0,22815777 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,21763179 0,2280584 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,21763179 0,22795912 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,21763179 0,22785992 ! hexose catabolic process GO:0019320 104 67 0,000 0,21763179 0,2277608 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,21763179 0,22766178 ! activation of immune response GO:0002253 105 67 0,000 0,21763179 0,22756284 ! amino acid transport GO:0006865 125 68 0,000 0,2204957 0,23045728 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,2204957 0,23035721 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,2204957 0,23025723 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,2204957 0,23015734 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,2204957 0,23005753 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,2204957 0,22995781 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,22334922 0,23283286 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,22334922 0,23273202 ! urogenital system development GO:0001655 137 69 0,000 0,22334922 0,23263127 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,22334922 0,23253061 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,22334922 0,23243003 ! antigen processing and presentation GO:0019882 104 69 0,000 0,22334922 0,23232954 ! amine catabolic process GO:0009310 117 71 0,000 0,22902525 0,23813084 ! reproductive structure development GO:0048608 113 71 0,000 0,22902525 0,23802797 ! humoral immune response GO:0006959 109 71 0,000 0,22902525 0,2379252 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,22902525 0,23782251 ! regulation of immune effector process GO:0002697 137 71 0,000 0,22902525 0,23771991 ! acute inflammatory response GO:0002526 113 72 0,000 0,23184783 0,24054587 ! carbohydrate transport GO:0008643 110 72 0,000 0,23184783 0,24044219 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,23184783 0,24033859 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,23184783 0,24023509 ! regulation of blood pressure GO:0008217 125 73 0,000 0,23466017 0,2430445 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,23466017 0,24293992 ! fertilization GO:0009566 90 73 0,000 0,23466017 0,24283543 ! transition metal ion transport GO:0000041 126 74 0,000 0,23746231 0,24562954 ! exocytosis GO:0006887 133 74 0,000 0,23746231 0,24552398 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,23746231 0,24541852 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,23746231 0,24531314 ! eye development GO:0001654 143 74 0,000 0,23746231 0,24520786 ! organelle localization GO:0051640 136 74 0,000 0,23746231 0,24510266 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,24025428 0,24787812 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,24025428 0,24777188 ! rhythmic process GO:0048511 128 75 0,000 0,24025428 0,24766572 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,24303611 0,25042608 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,24303611 0,25031888 ! defense response to bacterium GO:0042742 89 76 0,000 0,24303611 0,25021176 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,24303611 0,25010474 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,24303611 0,24999782 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,24580786 0,2527409 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,24580786 0,25263294 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,24580786 0,25252507 ! blood coagulation GO:0007596 146 78 0,000 0,24856955 0,25525324 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,24856955 0,25514434 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,24856955 0,25503554 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,25132122 0,25774887 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,25132122 0,25763905 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,25132122 0,25752932 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,25132122 0,25741969 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,2540629 0,26011717 ! muscle cell differentiation GO:0042692 159 80 0,000 0,2540629 0,26000652 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,2540629 0,25989598 ! inorganic anion transport GO:0015698 138 80 0,000 0,2540629 0,25978552 ! digestion GO:0007586 112 81 0,000 0,25679463 0,26246724 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,25679463 0,26235579 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,25679463 0,26224444 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,25679463 0,26213317 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,25951645 0,26479923 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,25951645 0,26468698 ! response to nutrient GO:0007584 125 82 0,000 0,25951645 0,26457483 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,25951645 0,26446277 ! regulation of lyase activity GO:0051339 160 83 0,000 0,2622284 0,26711326 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,2649305 0,26975149 ! hemostasis GO:0007599 158 84 0,000 0,2649305 0,26963738 ! regulation of ligase activity GO:0051340 142 84 0,000 0,2649305 0,26952337 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,2649305 0,26940946 ! nucleosome assembly GO:0006334 122 85 0,000 0,26762279 0,27203229 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,26762279 0,27191741 ! amine biosynthetic process GO:0009309 138 86 0,000 0,27030531 0,27452705 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,27030531 0,27441122 ! chromatin assembly GO:0031497 124 86 0,000 0,27030531 0,27429548 ! tube morphogenesis GO:0035239 176 86 0,000 0,27030531 0,27417984 ! alcohol catabolic process GO:0046164 130 86 0,000 0,27030531 0,2740643 ! amine transport GO:0015837 155 86 0,000 0,27030531 0,27394885 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,2729781 0,27654118 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,2729781 0,27642479 ! cellular respiration GO:0045333 135 88 0,000 0,27564118 0,27900407 ! regulation of neurological system process GO:0031644 148 88 0,000 0,27564118 0,27888675 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,27564118 0,27876952 ! cellular defense response GO:0006968 114 89 0,000 0,2782946 0,28133479 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,28093838 0,28388818 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,28093838 0,283769 ! sex differentiation GO:0007548 145 90 0,000 0,28093838 0,28364992 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,28093838 0,28353094 ! sterol metabolic process GO:0016125 152 91 0,000 0,28357257 0,28606944 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,28357257 0,28594954 ! regulation of defense response GO:0031347 149 92 0,000 0,2861972 0,28847527 ! nucleosome organization GO:0034728 138 92 0,000 0,2861972 0,28835446 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,2861972 0,28823376 ! vitamin metabolic process GO:0006766 139 92 0,000 0,2861972 0,28811316 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,2888123 0,29062417 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,2888123 0,29050267 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,2888123 0,29038127 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,2914179 0,29287864 ! female pregnancy GO:0007565 164 94 0,000 0,2914179 0,29275635 ! forebrain development GO:0030900 188 95 0,000 0,29401404 0,29524115 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,29401404 0,29511798 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,29660076 0,29759026 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,29660076 0,29746621 ! positive regulation of immune response GO:0050778 156 96 0,000 0,29660076 0,29734226 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,29917809 0,29980112 ! hormone metabolic process GO:0042445 157 97 0,000 0,29917809 0,2996763 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,30174606 0,30212277 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,30174606 0,30199709 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,3043047 0,30443123 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,3043047 0,3043047