pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6554-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cell migration GO:0030334 71 71 6,000 1,991E-08 3,669E-05 ! regulation of locomotion GO:0040012 79 79 6,000 4,234E-08 3,902E-05 ! regulation of cell motion GO:0051270 79 79 6,000 4,234E-08 2,601E-05 ! chloride transport GO:0006821 27 27 4,000 9,976E-08 4,596E-05 ! protein amino acid autophosphorylation GO:0046777 28 28 4,000 1,211E-07 4,462E-05 ! inorganic anion transport GO:0015698 35 35 4,000 3,911E-07 1,201E-04 ! positive regulation of cell migration GO:0030335 36 36 4,000 4,528E-07 1,192E-04 ! positive regulation of cell motion GO:0051272 39 39 4,000 6,85E-07 1,578E-04 ! regulation of lipid kinase activity GO:0043550 6 6 2,000 1,642E-06 3,362E-04 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 1,642E-06 3,026E-04 ! positive regulation of transferase activity GO:0051347 91 88 5,000 2,1E-06 3,519E-04 GO:0033674|positive regulation of kinase activity, ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 2,000 6,833E-06 1,049E-03 ! anion transport GO:0006820 65 65 4,000 9,052E-06 1,283E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 1,334E-05 1,756E-03 ! vasculogenesis GO:0001570 13 13 2,000 2,298E-05 2,824E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 2,298E-05 2,647E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 2,298E-05 2,492E-03 ! protein tetramerization GO:0051262 13 13 2,000 2,298E-05 2,353E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 2,916E-05 2,829E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 3,634E-05 3,349E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 3,634E-05 3,189E-03 ! heart development GO:0007507 90 87 4,000 3,777E-05 3,164E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 4,459E-05 3,573E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 6,204E-05 4,764E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 2,000 6,458E-05 4,761E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 7,645E-05 5,419E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 8,967E-05 6,121E-03 ! mammary gland development GO:0030879 23 21 2,000 1,043E-04 6,865E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 1,043E-04 6,628E-03 ! glucan metabolic process GO:0044042 25 24 2,000 1,573E-04 9,662E-03 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,782E-04 0,01059262 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,949E-04 0,0112222 ! filopodium assembly GO:0046847 7 5 1,000 1,949E-04 0,01088213 GO:0030035|microspike assembly, ! mRNA stabilization GO:0048255 5 5 1,000 1,949E-04 0,01056207 GO:0043489|RNA stabilization, ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 1,949E-04 0,0102603 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,949E-04 9,975E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,949E-04 9,706E-03 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 1,949E-04 9,45E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 1,949E-04 9,208E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,949E-04 8,978E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 1,949E-04 8,759E-03 ! nucleus localization GO:0051647 5 5 1,000 1,949E-04 8,55E-03 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 2,001E-04 8,574E-03 ! negative regulation of cell migration GO:0030336 26 26 2,000 2,008E-04 8,411E-03 ! double-strand break repair GO:0006302 27 26 2,000 2,008E-04 8,224E-03 ! response to insulin stimulus GO:0032868 28 26 2,000 2,008E-04 8,045E-03 ! energy reserve metabolic process GO:0006112 28 27 2,000 2,252E-04 8,831E-03 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 2,377E-04 9,127E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 2,796E-04 0,01051739 ! response to UV GO:0009411 29 29 2,000 2,796E-04 0,01030704 ! virus-host interaction GO:0019048 6 6 1,000 2,915E-04 0,0105324 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 2,915E-04 0,01032986 GO:0050927|positive regulation of positive chemotaxis, ! pathogenesis GO:0009405 6 6 1,000 2,915E-04 0,01013495 ! ER overload response GO:0006983 6 6 1,000 2,915E-04 9,947E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,915E-04 9,766E-03 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 2,915E-04 9,592E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 2,915E-04 9,424E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,915E-04 9,261E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,915E-04 9,104E-03 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 2,915E-04 8,953E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,915E-04 8,806E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 2,915E-04 8,664E-03 ! localization within membrane GO:0051668 6 6 1,000 2,915E-04 8,526E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 3,419E-04 9,845E-03 ! negative regulation of cell motion GO:0051271 31 31 2,000 3,419E-04 9,694E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 4,069E-04 0,01136215 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 4,069E-04 0,01119257 GO:0000725|recombinational repair, ! gene silencing by RNA GO:0031047 7 7 1,000 4,069E-04 0,01102797 ! regulation of mRNA processing GO:0050684 7 7 1,000 4,069E-04 0,01086814 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 4,069E-04 0,01071288 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 1,000 4,069E-04 0,010562 ! response to X-ray GO:0010165 7 7 1,000 4,069E-04 0,0104153 ! regulation of intracellular pH GO:0051453 7 7 1,000 4,069E-04 0,01027263 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 4,069E-04 0,01013381 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 8 7 1,000 4,069E-04 9,999E-03 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 4,069E-04 9,867E-03 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 4,069E-04 9,739E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 4,069E-04 9,614E-03 ! regulation of lipid metabolic process GO:0019216 34 34 2,000 4,51E-04 0,01052146 ! cellular polysaccharide metabolic process GO:0044264 35 34 2,000 4,51E-04 0,01038994 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 4,51E-04 0,01026167 ! blood vessel morphogenesis GO:0048514 84 83 3,000 4,835E-04 0,01086782 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 4,918E-04 0,0109199 ! regulation of mitosis GO:0007088 37 36 2,000 5,349E-04 0,01173496 GO:0051783|regulation of nuclear division, ! negative regulation of bone remodeling GO:0046851 8 8 1,000 5,41E-04 0,01173014 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 5,41E-04 0,01159375 ! sex determination GO:0007530 8 8 1,000 5,41E-04 0,01146048 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 5,41E-04 0,01133025 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 5,41E-04 0,01120294 ! regulation of RNA stability GO:0043487 8 8 1,000 5,41E-04 0,01107847 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 5,41E-04 0,01095673 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 5,41E-04 0,01083763 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 5,535E-04 0,0109695 ! meiosis GO:0007126 37 37 2,000 5,803E-04 0,0113771 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 2,000 5,803E-04 0,01125734 ! meiotic cell cycle GO:0051321 38 38 2,000 6,281E-04 0,01205813 ! respiratory tube development GO:0030323 40 39 2,000 6,784E-04 0,01288895 ! response to unfolded protein GO:0006986 39 39 2,000 6,784E-04 0,01275743 ! respiratory system development GO:0060541 40 39 2,000 6,784E-04 0,01262857 ! protein oligomerization GO:0051259 39 39 2,000 6,784E-04 0,01250228 ! negative regulation of cell cycle GO:0045786 92 91 3,000 6,858E-04 0,01251433 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 6,936E-04 0,01253273 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 6,936E-04 0,01241106 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 6,936E-04 0,01229172 ! regulation of cellular pH GO:0030641 9 9 1,000 6,936E-04 0,01217466 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 6,936E-04 0,0120598 ! regulation of leukocyte migration GO:0002685 9 9 1,000 6,936E-04 0,01194709 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 6,936E-04 0,01183647 ! blood vessel development GO:0001568 95 94 3,000 7,752E-04 0,01310668 ! vasculature development GO:0001944 97 96 3,000 8,391E-04 0,01405929 ! response to protein stimulus GO:0051789 42 42 2,000 8,444E-04 0,01401969 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 8,646E-04 0,01422714 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 8,646E-04 0,01410124 ! inositol metabolic process GO:0006020 10 10 1,000 8,646E-04 0,01397754 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 8,646E-04 0,013856 ! auditory receptor cell differentiation GO:0042491 10 10 1,000 8,646E-04 0,01373655 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 8,646E-04 0,01361914 ! cellular response to unfolded protein GO:0034620 10 10 1,000 8,646E-04 0,01350373 GO:0030968|endoplasmic reticulum unfolded protein response, ! neuromuscular junction development GO:0007528 10 10 1,000 8,646E-04 0,01339025 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 8,646E-04 0,01327866 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 8,646E-04 0,01316892 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 1,054E-03 0,01591864 ! endothelial cell migration GO:0043542 11 11 1,000 1,054E-03 0,01578922 ! cellular response to starvation GO:0009267 11 11 1,000 1,054E-03 0,01566189 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 1,054E-03 0,01553659 ! G1/S transition checkpoint GO:0031575 12 11 1,000 1,054E-03 0,01541328 ! interaction with host GO:0051701 11 11 1,000 1,054E-03 0,01529192 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,054E-03 0,01517245 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 1,054E-03 0,01505484 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,054E-03 0,01493903 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 1,103E-03 0,01551769 ! regulation of catabolic process GO:0009894 48 47 2,000 1,175E-03 0,01640011 ! regulation of cell cycle process GO:0010564 50 48 2,000 1,249E-03 0,01730912 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 1,261E-03 0,01734293 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 1,261E-03 0,01721446 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 1,261E-03 0,01708788 ! leukocyte differentiation GO:0002521 50 49 2,000 1,327E-03 0,01784521 ! gland development GO:0048732 51 49 2,000 1,327E-03 0,01771589 ! cell cycle arrest GO:0007050 49 49 2,000 1,327E-03 0,01758844 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 1,407E-03 0,01852097 ! positive regulation of DNA replication GO:0045740 14 13 1,000 1,486E-03 0,01942403 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 1,486E-03 0,01928724 ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,486E-03 0,01915236 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,486E-03 0,01901936 ! cell aging GO:0007569 13 13 1,000 1,486E-03 0,01888819 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,486E-03 0,01875882 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 1,486E-03 0,01863121 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 1,486E-03 0,01850532 ! positive regulation of locomotion GO:0040017 13 13 1,000 1,486E-03 0,01838113 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 1,486E-03 0,01825859 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,486E-03 0,01813767 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 1,486E-03 0,01801834 GO:0001952|regulation of cell-matrix adhesion, ! tissue homeostasis GO:0001894 13 13 1,000 1,486E-03 0,01790057 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 1,000 1,486E-03 0,01778434 ! response to light stimulus GO:0009416 53 52 2,000 1,577E-03 0,01874786 ! mechanoreceptor differentiation GO:0042490 14 14 1,000 1,729E-03 0,02042497 ! regulation of behavior GO:0050795 14 14 1,000 1,729E-03 0,02029487 ! base-excision repair GO:0006284 14 14 1,000 1,729E-03 0,02016642 ! neuromuscular process controlling balance GO:0050885 14 14 1,000 1,729E-03 0,02003959 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 1,759E-03 0,02026043 ! regulation of cell adhesion GO:0030155 56 55 2,000 1,855E-03 0,02123148 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,989E-03 0,02263081 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 1,989E-03 0,02249197 ! response to starvation GO:0042594 15 15 1,000 1,989E-03 0,02235482 ! response to ionizing radiation GO:0010212 16 15 1,000 1,989E-03 0,02221934 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,989E-03 0,02208549 ! inner ear morphogenesis GO:0042472 16 16 1,000 2,267E-03 0,02501911 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 2,267E-03 0,02487019 ! cellular response to nutrient levels GO:0031669 16 16 1,000 2,267E-03 0,02472303 ! polyol metabolic process GO:0019751 16 16 1,000 2,267E-03 0,0245776 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 2,27E-03 0,02447071 ! dephosphorylation GO:0016311 60 59 2,000 2,27E-03 0,02432844 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 2,562E-03 0,02729491 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 2,562E-03 0,02713805 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 2,562E-03 0,02698297 ! myelination GO:0042552 17 17 1,000 2,562E-03 0,02682966 ! tissue remodeling GO:0048771 17 17 1,000 2,562E-03 0,02667808 ! negative regulation of cell development GO:0010721 18 17 1,000 2,562E-03 0,0265282 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 2,562E-03 0,02638 ! gene silencing GO:0016458 17 17 1,000 2,562E-03 0,02623344 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 2,617E-03 0,02665133 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 2,74E-03 0,02774563 ! angiogenesis GO:0001525 65 64 2,000 2,866E-03 0,02886319 ! regulation of cell projection organization GO:0031344 19 18 1,000 2,874E-03 0,02879019 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 2,874E-03 0,02863457 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,874E-03 0,02848062 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,874E-03 0,02832832 ! B cell differentiation GO:0030183 18 18 1,000 2,874E-03 0,02817763 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,874E-03 0,02802855 ! ensheathment of neurons GO:0007272 18 18 1,000 2,874E-03 0,02788103 GO:0008366|axon ensheathment, ! polysaccharide metabolic process GO:0005976 69 66 2,000 3,129E-03 0,03018883 ! DNA damage checkpoint GO:0000077 19 19 1,000 3,203E-03 0,03075022 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 3,203E-03 0,03059089 ! regulation of pH GO:0006885 19 19 1,000 3,203E-03 0,0304332 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 3,203E-03 0,03027714 ! peripheral nervous system development GO:0007422 19 19 1,000 3,203E-03 0,03012266 ! regulation of protein stability GO:0031647 19 19 1,000 3,203E-03 0,02996975 ! regulation of cell shape GO:0008360 21 19 1,000 3,203E-03 0,02981839 ! striated muscle tissue development GO:0014706 69 67 2,000 3,265E-03 0,03024135 ! response to radiation GO:0009314 70 68 2,000 3,406E-03 0,03138338 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 3,549E-03 0,03254569 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 3,549E-03 0,03238457 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 3,549E-03 0,03222504 ! RNA modification GO:0009451 20 20 1,000 3,549E-03 0,03206708 ! response to nutrient levels GO:0031667 69 69 2,000 3,55E-03 0,03191251 ! muscle tissue development GO:0060537 72 70 2,000 3,697E-03 0,0330789 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 3,912E-03 0,03483115 ! receptor-mediated endocytosis GO:0006898 21 21 1,000 3,912E-03 0,0346637 ! DNA integrity checkpoint GO:0031570 21 21 1,000 3,912E-03 0,03449784 ! negative regulation of protein transport GO:0051224 21 21 1,000 3,912E-03 0,03433356 ! ear morphogenesis GO:0042471 21 21 1,000 3,912E-03 0,03417085 ! regulation of action potential in neuron GO:0019228 21 21 1,000 3,912E-03 0,03400966 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 3,912E-03 0,03384999 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 4,004E-03 0,03448245 ! response to extracellular stimulus GO:0009991 72 72 2,000 4,004E-03 0,03432207 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 4,291E-03 0,03661511 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 4,687E-03 0,03980581 ! positive regulation of growth GO:0045927 23 23 1,000 4,687E-03 0,03962322 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 4,687E-03 0,03944229 ! calcium-mediated signaling GO:0019722 23 23 1,000 4,687E-03 0,03926301 ! Rho protein signal transduction GO:0007266 24 23 1,000 4,687E-03 0,03908535 ! cell projection assembly GO:0030031 25 23 1,000 4,687E-03 0,03890929 ! mitochondrial transport GO:0006839 24 24 1,000 5,099E-03 0,04213799 ! regulation of action potential GO:0001508 24 24 1,000 5,099E-03 0,04194987 ! glucose homeostasis GO:0042593 24 24 1,000 5,099E-03 0,04176343 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 5,099E-03 0,04157864 ! neuron projection development GO:0031175 85 80 2,000 5,383E-03 0,04370765 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 5,526E-03 0,04467249 ! regulation of T cell proliferation GO:0042129 25 25 1,000 5,526E-03 0,04447742 ! heart morphogenesis GO:0003007 25 25 1,000 5,526E-03 0,04428404 ! negative regulation of immune system process GO:0002683 25 25 1,000 5,526E-03 0,04409233 ! tube development GO:0035295 83 81 2,000 5,574E-03 0,04427591 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 5,97E-03 0,04722432 ! regulation of T cell differentiation GO:0045580 26 26 1,000 5,97E-03 0,04702251 ! synapse organization GO:0050808 26 26 1,000 5,97E-03 0,04682241 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 6,43E-03 0,05021323 ! activation of caspase activity GO:0006919 27 27 1,000 6,43E-03 0,05000136 ! inner ear development GO:0048839 27 27 1,000 6,43E-03 0,04979127 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 6,585E-03 0,0507765 ! neuromuscular process GO:0050905 28 28 1,000 6,905E-03 0,05302598 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 6,905E-03 0,05280596 ! male gamete generation GO:0048232 90 88 2,000 7,018E-03 0,05344589 GO:0007283|spermatogenesis, ! positive regulation of cell cycle GO:0045787 29 29 1,000 7,396E-03 0,05609361 ! viral reproductive process GO:0022415 29 29 1,000 7,396E-03 0,05586371 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 7,396E-03 0,0556357 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 7,396E-03 0,05540954 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 7,396E-03 0,05518521 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! positive regulation of peptidase activity GO:0010952 30 30 1,000 7,902E-03 0,05872417 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 7,902E-03 0,05848833 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 7,902E-03 0,05825438 ! vascular process in circulatory system GO:0003018 31 30 1,000 7,902E-03 0,05802229 ! establishment of organelle localization GO:0051656 31 30 1,000 7,902E-03 0,05779204 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 7,934E-03 0,05779799 ! skeletal muscle fiber development GO:0048741 31 31 1,000 8,424E-03 0,06112018 ! B cell activation GO:0042113 31 31 1,000 8,424E-03 0,06088049 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 8,424E-03 0,06064267 ! aging GO:0007568 32 31 1,000 8,424E-03 0,06040671 ! regulation of intracellular transport GO:0032386 31 31 1,000 8,424E-03 0,06017258 ! negative regulation of cell growth GO:0030308 32 32 1,000 8,96E-03 0,06375784 ! muscle fiber development GO:0048747 32 32 1,000 8,96E-03 0,06351262 ! lipid modification GO:0030258 32 32 1,000 8,96E-03 0,06326928 ! regulation of phospholipase activity GO:0010517 32 32 1,000 8,96E-03 0,06302779 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 8,96E-03 0,06278814 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 8,96E-03 0,06255031 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 8,96E-03 0,06231427 ! positive regulation of lipase activity GO:0060193 32 32 1,000 8,96E-03 0,06208001 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 9,436E-03 0,06513614 ! negative regulation of cell size GO:0045792 33 33 1,000 9,511E-03 0,065409 ! regulation of protein complex assembly GO:0043254 33 33 1,000 9,511E-03 0,06516584 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 9,511E-03 0,06492449 ! response to hormone stimulus GO:0009725 102 100 2,000 9,972E-03 0,06781488 ! muscle organ development GO:0007517 102 100 2,000 9,972E-03 0,06756556 ! hemopoiesis GO:0030097 104 100 2,000 9,972E-03 0,06731807 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,01007773 0,06778563 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,01007773 0,06753914 ! ear development GO:0043583 34 34 1,000 0,01007773 0,06729443 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,01007773 0,06705149 ! viral reproduction GO:0016032 34 34 1,000 0,01007773 0,0668103 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,0106587 0,07040854 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,0106587 0,07015709 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,0106587 0,06990742 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01125422 0,07355152 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,01125422 0,07329162 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01125422 0,07303355 ! response to drug GO:0042493 37 37 1,000 0,01186416 0,07672157 ! negative regulation of growth GO:0045926 37 37 1,000 0,01186416 0,07645331 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,01186416 0,07618692 ! adaptive immune response GO:0002250 37 37 1,000 0,01186416 0,07592238 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! axon guidance GO:0007411 39 38 1,000 0,01248839 0,07964047 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,01248839 0,07936584 ! activation of MAPK activity GO:0000187 39 39 1,000 0,01312677 0,08313618 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01312677 0,08285147 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,01312677 0,0825687 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01312677 0,08228785 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,01377917 0,08608476 ! organelle localization GO:0051640 41 40 1,000 0,01377917 0,08579393 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,01444546 0,08963967 ! regulation of caspase activity GO:0043281 41 41 1,000 0,01444546 0,08933887 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,01512551 0,09323185 ! protein ubiquitination GO:0016567 43 42 1,000 0,01512551 0,09292107 ! mitochondrion organization GO:0007005 44 43 1,000 0,0158192 0,09685975 ! protein import into nucleus GO:0006606 44 44 1,000 0,01652639 0,10085476 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01724696 0,10490476 ! nuclear import GO:0051170 45 45 1,000 0,01724696 0,10455968 ! tube morphogenesis GO:0035239 47 46 1,000 0,01798077 0,10865104 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,01798077 0,10829597 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01798077 0,10794321 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,01948765 0,11660956 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01948765 0,11623219 ! DNA recombination GO:0006310 48 48 1,000 0,01948765 0,11585724 ! ossification GO:0001503 50 49 1,000 0,02026047 0,12006444 GO:0060348|bone development, ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,02026047 0,11967962 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 1,000 0,02026047 0,11929726 ! negative regulation of transport GO:0051051 51 50 1,000 0,02104603 0,12352814 ! chromatin assembly GO:0031497 50 50 1,000 0,02104603 0,12313599 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 1,000 0,02104603 0,12274632 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,02104603 0,12235911 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,02104603 0,12197433 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,02184423 0,12620347 ! protein-DNA complex assembly GO:0065004 51 51 1,000 0,02184423 0,12580909 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,02184423 0,12541716 GO:0051325|interphase, ! rRNA transcription GO:0009303 5 5 0,000 0,02233339 0,12782747 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02233339 0,12743172 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02233339 0,12703841 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02233339 0,12664752 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02233339 0,12625903 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02233339 0,12587292 ! reproductive cellular process GO:0048610 5 5 0,000 0,02233339 0,12548916 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02233339 0,12510773 ! prostate gland development GO:0030850 5 5 0,000 0,02233339 0,12472862 ! metencephalon development GO:0022037 5 5 0,000 0,02233339 0,1243518 ! water transport GO:0006833 5 5 0,000 0,02233339 0,12397724 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02233339 0,12360494 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02233339 0,12323486 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02233339 0,122867 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02233339 0,12250132 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02233339 0,12213782 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02233339 0,12177646 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02233339 0,12141724 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02233339 0,12106013 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02233339 0,12070512 ! CTP metabolic process GO:0046036 5 5 0,000 0,02233339 0,12035218 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02233339 0,1200013 ! GTP metabolic process GO:0046039 5 5 0,000 0,02233339 0,11965245 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02233339 0,11930564 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02233339 0,11896082 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02233339 0,118618 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02233339 0,11827714 ! social behavior GO:0035176 5 5 0,000 0,02233339 0,11793824 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02233339 0,11760127 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02233339 0,11726622 ! memory GO:0007613 5 5 0,000 0,02233339 0,11693308 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02233339 0,11660183 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02233339 0,11627244 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02233339 0,11594491 ! response to lipid GO:0033993 5 5 0,000 0,02233339 0,11561923 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02233339 0,11529536 ! hippocampus development GO:0021766 6 5 0,000 0,02233339 0,11497331 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02233339 0,11465305 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02233339 0,11433457 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02233339 0,11401785 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02233339 0,11370289 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02233339 0,11338965 ! heart looping GO:0001947 5 5 0,000 0,02233339 0,11307814 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02233339 0,11276834 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02233339 0,11246023 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02233339 0,1121538 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02233339 0,11184903 ! pH reduction GO:0045851 5 5 0,000 0,02233339 0,11154592 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02233339 0,11124444 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02233339 0,11094459 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02233339 0,11064636 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02233339 0,11034972 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02233339 0,11005466 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02233339 0,10976119 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02233339 0,10946927 ! adrenal gland development GO:0030325 5 5 0,000 0,02233339 0,1091789 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02233339 0,10889006 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02233339 0,10860276 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02233339 0,10831696 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02233339 0,10803266 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02233339 0,10774985 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02233339 0,10746852 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02233339 0,10718866 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02233339 0,10691025 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02233339 0,10663328 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02233339 0,10635774 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02233339 0,10608362 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02233339 0,10581091 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02233339 0,1055396 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02233339 0,10526968 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02233339 0,10500113 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02233339 0,10473396 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02233339 0,10446813 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02233339 0,10420366 ! response to ATP GO:0033198 5 5 0,000 0,02233339 0,10394052 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02233339 0,1036787 ! regulation of appetite GO:0032098 5 5 0,000 0,02233339 0,1034182 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02233339 0,10315901 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02233339 0,10290111 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02233339 0,1026445 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02233339 0,10238917 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02233339 0,1021351 ! receptor clustering GO:0043113 5 5 0,000 0,02233339 0,10188229 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02233339 0,10163073 ! fear response GO:0042596 5 5 0,000 0,02233339 0,1013804 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02233339 0,10113131 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02233339 0,10088344 ! retinol metabolic process GO:0042572 5 5 0,000 0,02233339 0,10063678 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02233339 0,10039133 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02233339 0,10014707 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02233339 0,09990399 ! parturition GO:0007567 5 5 0,000 0,02233339 0,09966209 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02233339 0,09942136 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02233339 0,09918179 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02233339 0,09894338 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02233339 0,0987061 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02233339 0,09846996 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02233339 0,09823495 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02233339 0,09800106 ! response to UV-B GO:0010224 5 5 0,000 0,02233339 0,09776828 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02233339 0,0975366 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02233339 0,09730602 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02233339 0,09707652 ! interaction with symbiont GO:0051702 5 5 0,000 0,02233339 0,0968481 ! cellular extravasation GO:0045123 5 5 0,000 0,02233339 0,09662076 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02233339 0,09639448 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02233339 0,09616926 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02233339 0,09594509 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02233339 0,09572196 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02233339 0,09549987 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02233339 0,09527881 ! response to amine stimulus GO:0014075 5 5 0,000 0,02233339 0,09505876 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02233339 0,09483973 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02233339 0,09462171 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02233339 0,09440469 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02233339 0,09418866 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02233339 0,09397362 ! neuron recognition GO:0008038 5 5 0,000 0,02233339 0,09375955 ! decidualization GO:0046697 5 5 0,000 0,02233339 0,09354646 ! hair follicle maturation GO:0048820 5 5 0,000 0,02233339 0,09333434 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02233339 0,09312318 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02233339 0,09291297 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02233339 0,0927037 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02233339 0,09249538 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02233339 0,09228799 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02233339 0,09208153 ! postreplication repair GO:0006301 5 5 0,000 0,02233339 0,09187599 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02233339 0,09167137 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02233339 0,09146765 ! histone methylation GO:0016571 5 5 0,000 0,02233339 0,09126484 ! DNA methylation GO:0006306 5 5 0,000 0,02233339 0,09106293 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02233339 0,09086191 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02233339 0,09066177 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02233339 0,09046252 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02233339 0,09026413 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02233339 0,09006662 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02233339 0,08986997 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02233339 0,08967417 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02233339 0,08947923 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02233339 0,08928513 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02233339 0,08909187 ! sterol catabolic process GO:0016127 5 5 0,000 0,02233339 0,08889945 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02233339 0,08870785 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02233339 0,08851708 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02233339 0,08832713 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02233339 0,088138 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02233339 0,08794967 ! zymogen activation GO:0031638 5 5 0,000 0,02233339 0,08776214 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02233339 0,08757541 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02233339 0,08738948 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02233339 0,08720433 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,02233339 0,08701997 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02233339 0,08683638 ! nucleosome positioning GO:0016584 5 5 0,000 0,02233339 0,08665357 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02233339 0,08647152 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02233339 0,08629024 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02233339 0,08610972 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02233339 0,08592995 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02233339 0,08575093 ! NADPH regeneration GO:0006740 5 5 0,000 0,02233339 0,08557265 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02233339 0,08539511 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02233339 0,08521831 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02233339 0,08504224 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02233339 0,0848669 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02233339 0,08469227 ! sarcomere organization GO:0045214 5 5 0,000 0,02233339 0,08451837 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02233339 0,08434517 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02233339 0,08417269 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02233339 0,08400091 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02233339 0,08382983 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02233339 0,08365944 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02233339 0,08348975 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02233339 0,08332074 ! spleen development GO:0048536 5 5 0,000 0,02233339 0,08315241 ! male genitalia development GO:0030539 5 5 0,000 0,02233339 0,08298477 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02233339 0,0828178 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02233339 0,08265149 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02233339 0,08248586 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02233339 0,08232089 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02233339 0,08215658 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02233339 0,08199292 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02233339 0,08182991 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02233339 0,08166755 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02233339 0,08150583 ! ATP catabolic process GO:0006200 5 5 0,000 0,02233339 0,08134475 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02233339 0,08118431 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02233339 0,0810245 ! blastocyst formation GO:0001825 5 5 0,000 0,02233339 0,08086531 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02233339 0,08070675 ! embryonic gut development GO:0048566 5 5 0,000 0,02233339 0,08054881 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02233339 0,08039149 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02233339 0,08023478 ! activation of innate immune response GO:0002218 5 5 0,000 0,02233339 0,08007869 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,02233339 0,07992319 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02233339 0,0797683 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02233339 0,07961401 ! muscle adaptation GO:0043500 5 5 0,000 0,02233339 0,07946032 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02233339 0,07930721 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02233339 0,0791547 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02233339 0,07900277 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02233339 0,07885143 ! defense response to fungus GO:0050832 5 5 0,000 0,02233339 0,07870066 ! lysogeny GO:0030069 5 5 0,000 0,02233339 0,07855047 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02233339 0,07840085 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02233339 0,0782518 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02233339 0,07810331 ! response to nicotine GO:0035094 5 5 0,000 0,02233339 0,07795539 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02233339 0,07780802 ! mitochondrion localization GO:0051646 5 5 0,000 0,02233339 0,07766122 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02233339 0,07751496 ! cell fate commitment GO:0045165 52 52 1,000 0,02265493 0,07848313 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,02265493 0,07833589 ! response to hypoxia GO:0001666 53 53 1,000 0,02347801 0,08102991 ! regulation of T cell activation GO:0050863 53 53 1,000 0,02347801 0,08087845 ! regulation of protein transport GO:0051223 53 53 1,000 0,02347801 0,08072756 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 1,000 0,02431336 0,08344418 ! response to virus GO:0009615 54 54 1,000 0,02431336 0,08328908 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,02431336 0,08313455 ! nucleosome organization GO:0034728 55 55 1,000 0,02516086 0,08587307 ! in utero embryonic development GO:0001701 55 55 1,000 0,02516086 0,08571434 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,02516086 0,08555619 ! reproductive developmental process GO:0003006 56 56 1,000 0,02602038 0,08831594 ! extracellular structure organization GO:0043062 56 56 1,000 0,02602038 0,0881536 ! regulation of nervous system development GO:0051960 57 56 1,000 0,02602038 0,08799185 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02674178 0,09026576 ! axon extension GO:0048675 7 6 0,000 0,02674178 0,09010074 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02674178 0,08993632 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,02674178 0,0897725 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,02674178 0,08960928 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02674178 0,08944665 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02674178 0,08928461 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02674178 0,08912315 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02674178 0,08896228 ! regulation of S phase GO:0033261 6 6 0,000 0,02674178 0,08880199 ! myotube differentiation GO:0014902 6 6 0,000 0,02674178 0,08864227 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02674178 0,08848313 ! bone remodeling GO:0046849 6 6 0,000 0,02674178 0,08832456 ! N-glycan processing GO:0006491 6 6 0,000 0,02674178 0,08816655 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02674178 0,08800911 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02674178 0,08785223 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02674178 0,08769591 ! RNA methylation GO:0001510 6 6 0,000 0,02674178 0,08754015 ! cartilage condensation GO:0001502 7 6 0,000 0,02674178 0,08738493 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02674178 0,08723027 ! succinate metabolic process GO:0006105 7 6 0,000 0,02674178 0,08707615 ! artery development GO:0060840 6 6 0,000 0,02674178 0,08692258 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02674178 0,08676955 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02674178 0,08661705 ! androgen metabolic process GO:0008209 6 6 0,000 0,02674178 0,08646509 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02674178 0,08631367 ! limbic system development GO:0021761 7 6 0,000 0,02674178 0,08616277 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02674178 0,0860124 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02674178 0,08586255 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02674178 0,08571322 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02674178 0,08556441 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02674178 0,08541612 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02674178 0,08526834 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02674178 0,08512108 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02674178 0,08497432 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02674178 0,08482806 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02674178 0,08468231 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02674178 0,08453705 ! arginine metabolic process GO:0006525 6 6 0,000 0,02674178 0,0843923 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02674178 0,08424804 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02674178 0,08410427 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02674178 0,08396099 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02674178 0,0838182 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02674178 0,0836759 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02674178 0,08353407 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02674178 0,08339273 ! V(D)J recombination GO:0033151 6 6 0,000 0,02674178 0,08325186 ! focal adhesion formation GO:0048041 7 6 0,000 0,02674178 0,08311147 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02674178 0,08297155 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02674178 0,08283211 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02674178 0,08269313 ! regulation of heart rate GO:0002027 6 6 0,000 0,02674178 0,08255461 ! lipid digestion GO:0044241 6 6 0,000 0,02674178 0,08241656 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02674178 0,08227897 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02674178 0,08214184 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02674178 0,08200516 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02674178 0,08186894 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02674178 0,08173317 ! ruffle organization GO:0031529 6 6 0,000 0,02674178 0,08159785 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02674178 0,08146298 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02674178 0,08132855 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02674178 0,08119457 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02674178 0,08106102 ! L-amino acid transport GO:0015807 6 6 0,000 0,02674178 0,08092792 ! bone mineralization GO:0030282 6 6 0,000 0,02674178 0,08079525 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02674178 0,08066302 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02674178 0,08053121 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02674178 0,08039984 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02674178 0,0802689 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02674178 0,08013838 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02674178 0,08000828 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02674178 0,07987861 ! regulation of organ growth GO:0046620 6 6 0,000 0,02674178 0,07974936 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02674178 0,07962052 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02674178 0,0794921 ! response to dsRNA GO:0043331 6 6 0,000 0,02674178 0,07936409 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02674178 0,0792365 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02674178 0,07910931 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02674178 0,07898254 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02674178 0,07885616 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02674178 0,0787302 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02674178 0,07860463 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02674178 0,07847946 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02674178 0,07835469 ! erythrocyte development GO:0048821 6 6 0,000 0,02674178 0,07823032 ! renal water homeostasis GO:0003091 6 6 0,000 0,02674178 0,07810634 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02674178 0,07798276 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02674178 0,07785956 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02674178 0,07773676 ! ribosome assembly GO:0042255 6 6 0,000 0,02674178 0,07761434 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02674178 0,0774923 ! diencephalon development GO:0021536 6 6 0,000 0,02674178 0,07737065 ! fucose catabolic process GO:0019317 6 6 0,000 0,02674178 0,07724938 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02674178 0,07712849 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02674178 0,07700797 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02674178 0,07688784 ! regulation of cell division GO:0051302 6 6 0,000 0,02674178 0,07676807 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02674178 0,07664868 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02674178 0,07652966 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02674178 0,07641101 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02674178 0,07629273 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02674178 0,07617481 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02674178 0,07605726 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02674178 0,07594007 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02674178 0,07582324 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02674178 0,07570676 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02674178 0,07559065 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02674178 0,07547489 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02674178 0,07535948 ! thymus development GO:0048538 6 6 0,000 0,02674178 0,07524443 ! lymph node development GO:0048535 6 6 0,000 0,02674178 0,07512973 ! organic cation transport GO:0015695 6 6 0,000 0,02674178 0,07501538 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02674178 0,07490137 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02674178 0,07478771 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02674178 0,0746744 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02674178 0,07456143 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02674178 0,0744488 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02674178 0,0743365 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02674178 0,07422455 ! alditol metabolic process GO:0019400 6 6 0,000 0,02674178 0,07411294 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02674178 0,07400166 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02674178 0,07389071 ! maternal placenta development GO:0001893 6 6 0,000 0,02674178 0,07378009 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02674178 0,07366981 ! regulation of protein localization GO:0032880 58 57 1,000 0,02689181 0,07397254 ! regulation of cell development GO:0060284 60 59 1,000 0,02866993 0,07874616 ! protein localization in organelle GO:0033365 59 59 1,000 0,02866993 0,07862898 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,03049428 0,08350811 ! respiratory burst GO:0045730 7 7 0,000 0,03113093 0,08512508 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,03113093 0,08499897 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03113093 0,08487323 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,03113093 0,08474786 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03113093 0,08462287 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03113093 0,08449824 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03113093 0,08437397 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03113093 0,08425008 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03113093 0,08412654 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03113093 0,08400337 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03113093 0,08388056 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03113093 0,08375811 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,03113093 0,08363601 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03113093 0,08351427 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,03113093 0,08339288 ! axis specification GO:0009798 7 7 0,000 0,03113093 0,08327185 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03113093 0,08315116 ! visual behavior GO:0007632 7 7 0,000 0,03113093 0,08303083 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03113093 0,08291084 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03113093 0,0827912 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03113093 0,08267191 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03113093 0,08255295 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03113093 0,08243434 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03113093 0,08231607 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03113093 0,08219814 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03113093 0,08208055 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03113093 0,08196329 ! digestive system development GO:0055123 7 7 0,000 0,03113093 0,08184637 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03113093 0,08172978 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03113093 0,08161352 ! protein targeting to ER GO:0045047 8 7 0,000 0,03113093 0,08149759 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03113093 0,08138199 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03113093 0,08126672 ! endoderm development GO:0007492 7 7 0,000 0,03113093 0,08115177 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03113093 0,08103715 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03113093 0,08092285 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,03113093 0,08080888 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03113093 0,08069522 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03113093 0,08058189 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03113093 0,08046887 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03113093 0,08035617 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03113093 0,08024378 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03113093 0,08013171 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03113093 0,08001995 ! UV protection GO:0009650 7 7 0,000 0,03113093 0,0799085 ! DNA integration GO:0015074 7 7 0,000 0,03113093 0,07979736 ! myofibril assembly GO:0030239 7 7 0,000 0,03113093 0,07968653 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03113093 0,07957601 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03113093 0,07946579 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03113093 0,07935588 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03113093 0,07924627 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03113093 0,07913697 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03113093 0,07902797 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03113093 0,07891926 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03113093 0,07881086 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03113093 0,07870275 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03113093 0,07859494 ! axon cargo transport GO:0008088 7 7 0,000 0,03113093 0,07848742 ! eating behavior GO:0042755 7 7 0,000 0,03113093 0,0783802 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03113093 0,07827326 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03113093 0,07816663 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03113093 0,07806028 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03113093 0,07795422 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03113093 0,07784844 ! cranial nerve development GO:0021545 7 7 0,000 0,03113093 0,07774296 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03113093 0,07763776 ! induction of an organ GO:0001759 7 7 0,000 0,03113093 0,07753284 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03113093 0,07742821 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03113093 0,07732386 ! autonomic nervous system development GO:0048483 7 7 0,000 0,03113093 0,07721979 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03113093 0,077116 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03113093 0,07701249 ! platelet activation GO:0030168 8 7 0,000 0,03113093 0,07690925 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03113093 0,0768063 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03113093 0,07670361 ! natural killer cell activation GO:0030101 7 7 0,000 0,03113093 0,07660121 ! NADP metabolic process GO:0006739 7 7 0,000 0,03113093 0,07649907 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03113093 0,07639721 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03113093 0,07629562 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03113093 0,07619429 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,03113093 0,07609324 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03113093 0,07599245 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03113093 0,07589194 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03113093 0,07579168 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03113093 0,07569169 ! cell-cell recognition GO:0009988 8 7 0,000 0,03113093 0,07559197 ! hormone catabolic process GO:0042447 7 7 0,000 0,03113093 0,0754925 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03113093 0,0753933 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03113093 0,07529436 ! oxygen transport GO:0015671 7 7 0,000 0,03113093 0,07519568 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03113093 0,07509726 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03113093 0,07499909 ! regulation of axon extension GO:0030516 7 7 0,000 0,03113093 0,07490118 ! cell killing GO:0001906 7 7 0,000 0,03113093 0,07480352 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03113093 0,07470612 ! adult feeding behavior GO:0008343 7 7 0,000 0,03113093 0,07460898 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03113093 0,07451208 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03113093 0,07441544 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03113093 0,07431905 ! response to cold GO:0009409 7 7 0,000 0,03113093 0,0742229 ! axonogenesis GO:0007409 66 62 1,000 0,03142351 0,07482368 ! protein import GO:0017038 62 62 1,000 0,03142351 0,07472714 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,03142351 0,07463084 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,0333155 0,07902249 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,0333155 0,07892092 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,0333155 0,07881961 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,03427804 0,08099286 ! DNA packaging GO:0006323 66 66 1,000 0,03525146 0,08318623 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03550092 0,08366777 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03550092 0,08356091 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03550092 0,08345433 ! positive regulation of translation GO:0045727 8 8 0,000 0,03550092 0,08334802 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03550092 0,08324198 ! superoxide anion generation GO:0042554 8 8 0,000 0,03550092 0,08313621 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03550092 0,0830307 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03550092 0,08292547 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03550092 0,0828205 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03550092 0,0827158 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03550092 0,08261136 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03550092 0,08250718 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03550092 0,08240327 ! zinc ion transport GO:0006829 8 8 0,000 0,03550092 0,08229962 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03550092 0,08219622 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03550092 0,08209309 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03550092 0,08199022 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03550092 0,0818876 ! lipid localization GO:0010876 8 8 0,000 0,03550092 0,08178524 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03550092 0,08168314 ! response to cAMP GO:0051591 8 8 0,000 0,03550092 0,08158129 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03550092 0,08147969 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03550092 0,08137835 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03550092 0,08127726 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03550092 0,08117642 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03550092 0,08107583 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03550092 0,08097549 ! sensory perception of taste GO:0050909 8 8 0,000 0,03550092 0,08087539 ! organelle fusion GO:0048284 8 8 0,000 0,03550092 0,08077555 ! pancreas development GO:0031016 8 8 0,000 0,03550092 0,08067595 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03550092 0,08057659 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03550092 0,08047748 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03550092 0,08037862 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03550092 0,08027999 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03550092 0,08018161 ! sperm motility GO:0030317 8 8 0,000 0,03550092 0,08008347 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03550092 0,07998557 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03550092 0,07988791 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03550092 0,07979048 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03550092 0,07969329 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03550092 0,07959634 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03550092 0,07949963 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03550092 0,07940315 ! Golgi organization GO:0007030 8 8 0,000 0,03550092 0,0793069 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03550092 0,07921089 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03550092 0,07911511 ! fructose metabolic process GO:0006000 8 8 0,000 0,03550092 0,07901956 ! mannose metabolic process GO:0006013 9 8 0,000 0,03550092 0,07892424 ! NAD metabolic process GO:0019674 8 8 0,000 0,03550092 0,07882915 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03550092 0,07873429 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03550092 0,07863966 ! response to fungus GO:0009620 8 8 0,000 0,03550092 0,07854525 ! stem cell differentiation GO:0048863 8 8 0,000 0,03550092 0,07845107 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03550092 0,07835712 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03550092 0,07826339 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03550092 0,07816989 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03550092 0,0780766 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03550092 0,07798355 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03550092 0,07789071 ! vasoconstriction GO:0042310 8 8 0,000 0,03550092 0,07779809 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03550092 0,07770569 ! muscle cell development GO:0055001 8 8 0,000 0,03550092 0,07761352 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03550092 0,07752156 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03550092 0,07742982 ! sensory perception of pain GO:0019233 8 8 0,000 0,03550092 0,07733829 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03550092 0,07724698 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03550092 0,07715589 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03550092 0,07706501 ! chromatin silencing GO:0006342 8 8 0,000 0,03550092 0,07697435 ! tissue regeneration GO:0042246 8 8 0,000 0,03550092 0,07688389 ! salivary gland development GO:0007431 8 8 0,000 0,03550092 0,07679366 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03550092 0,07670363 ! T cell homeostasis GO:0043029 8 8 0,000 0,03550092 0,07661381 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03550092 0,0765242 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,03550092 0,07643481 ! water homeostasis GO:0030104 8 8 0,000 0,03550092 0,07634562 ! cofactor transport GO:0051181 8 8 0,000 0,03550092 0,07625664 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03550092 0,07616786 ! acid secretion GO:0046717 8 8 0,000 0,03550092 0,0760793 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03550092 0,07599093 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03550092 0,07590278 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03550092 0,07581483 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03550092 0,07572708 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03550092 0,07563953 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03550092 0,07555219 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03550092 0,07546505 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03550092 0,0753781 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03550092 0,07529136 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03550092 0,07520482 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03550092 0,07511848 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03550092 0,07503233 ! developmental induction GO:0031128 8 8 0,000 0,03550092 0,07494639 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03550092 0,07486063 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03550092 0,07477508 ! actin filament polymerization GO:0030041 9 8 0,000 0,03550092 0,07468972 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03550092 0,07460455 ! peptide hormone processing GO:0016486 8 8 0,000 0,03550092 0,07451958 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03550092 0,07443481 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03550092 0,07435022 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,03623565 0,07580284 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,03623565 0,0757169 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,03623565 0,07563115 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,0372305 0,07761969 ! regulation of cell size GO:0008361 68 68 1,000 0,0372305 0,07753199 ! sensory perception of sound GO:0007605 71 69 1,000 0,0382359 0,07953584 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,0382359 0,07944617 ! cell part morphogenesis GO:0032990 75 70 1,000 0,03925173 0,08146503 ! wound healing GO:0042060 74 70 1,000 0,03925173 0,08137339 ! lactation GO:0007595 10 9 0,000 0,03985183 0,08252464 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03985183 0,08243202 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03985183 0,0823396 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03985183 0,0822474 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03985183 0,0821554 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03985183 0,0820636 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03985183 0,08197202 ! viral genome replication GO:0019079 9 9 0,000 0,03985183 0,08188063 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03985183 0,08178945 ! copper ion transport GO:0006825 9 9 0,000 0,03985183 0,08169847 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03985183 0,0816077 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03985183 0,08151712 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03985183 0,08142675 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03985183 0,08133657 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03985183 0,0812466 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03985183 0,08115682 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03985183 0,08106725 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03985183 0,08097787 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03985183 0,08088869 ! phospholipid efflux GO:0033700 9 9 0,000 0,03985183 0,0807997 ! response to alkaloid GO:0043279 10 9 0,000 0,03985183 0,08071091 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03985183 0,08062231 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03985183 0,08053391 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03985183 0,0804457 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03985183 0,08035769 ! response to ethanol GO:0045471 9 9 0,000 0,03985183 0,08026986 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03985183 0,08018223 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03985183 0,08009479 ! methionine metabolic process GO:0006555 9 9 0,000 0,03985183 0,08000755 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03985183 0,07992049 ! cerebral cortex development GO:0021987 9 9 0,000 0,03985183 0,07983362 ! response to osmotic stress GO:0006970 9 9 0,000 0,03985183 0,07974693 ! pigmentation during development GO:0048066 9 9 0,000 0,03985183 0,07966044 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03985183 0,07957413 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03985183 0,07948802 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03985183 0,07940208 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03985183 0,07931634 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03985183 0,07923077 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03985183 0,07914539 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03985183 0,0790602 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03985183 0,07897519 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03985183 0,07889036 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03985183 0,07880572 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03985183 0,07872125 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03985183 0,07863697 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03985183 0,07855286 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03985183 0,07846894 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03985183 0,07838519 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03985183 0,07830163 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03985183 0,07821824 ! DNA replication initiation GO:0006270 9 9 0,000 0,03985183 0,07813503 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03985183 0,07805199 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03985183 0,07796914 ! histone acetylation GO:0016573 9 9 0,000 0,03985183 0,07788645 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03985183 0,07780395 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03985183 0,07772162 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03985183 0,07763946 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03985183 0,07755747 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03985183 0,07747566 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03985183 0,07739402 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03985183 0,07731255 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03985183 0,07723126 ! collagen catabolic process GO:0030574 9 9 0,000 0,03985183 0,07715013 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03985183 0,07706918 ! purine base metabolic process GO:0006144 9 9 0,000 0,03985183 0,07698839 ! gas transport GO:0015669 9 9 0,000 0,03985183 0,07690778 ! cholesterol efflux GO:0033344 9 9 0,000 0,03985183 0,07682733 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03985183 0,07674705 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03985183 0,07666694 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03985183 0,07658699 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03985183 0,07650722 ! defense response to virus GO:0051607 9 9 0,000 0,03985183 0,0764276 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03985183 0,07634816 ! actin filament-based movement GO:0030048 9 9 0,000 0,03985183 0,07626887 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03985183 0,07618976 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,04027791 0,07692454 ! regulation of cell activation GO:0050865 71 71 1,000 0,04027791 0,07684491 ! sensory organ development GO:0007423 72 72 1,000 0,04131431 0,07874071 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,04418375 0,08412257 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,04418375 0,08403576 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,04418375 0,08394912 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,04418375 0,08386266 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,04418375 0,08377639 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,04418375 0,08369028 ! neuron maturation GO:0042551 10 10 0,000 0,04418375 0,08360436 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,04418375 0,08351861 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,04418375 0,08343304 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,04418375 0,08334764 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,04418375 0,08326242 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,04418375 0,08317737 ! hormone secretion GO:0046879 10 10 0,000 0,04418375 0,0830925 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,04418375 0,0830078 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,04418375 0,08292327 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! cAMP metabolic process GO:0046058 10 10 0,000 0,04418375 0,08283891 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,04418375 0,08275472 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,04418375 0,08267071 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,04418375 0,08258686 ! glial cell development GO:0021782 10 10 0,000 0,04418375 0,08250319 ! phototransduction GO:0007602 11 10 0,000 0,04418375 0,08241968 ! fat cell differentiation GO:0045444 10 10 0,000 0,04418375 0,08233635 ! myoblast differentiation GO:0045445 10 10 0,000 0,04418375 0,08225318 ! centrosome cycle GO:0007098 10 10 0,000 0,04418375 0,08217018 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,04418375 0,08208735 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,04418375 0,08200468 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,04418375 0,08192218 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,04418375 0,08183985 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,04418375 0,08175768 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,04418375 0,08167567 ! protein polyubiquitination GO:0000209 10 10 0,000 0,04418375 0,08159383 ! glutamate metabolic process GO:0006536 11 10 0,000 0,04418375 0,08151216 ! plasma membrane organization GO:0007009 10 10 0,000 0,04418375 0,08143065 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,04418375 0,0813493 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,04418375 0,08126811 ! lysosomal transport GO:0007041 10 10 0,000 0,04418375 0,08118709 ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,04418375 0,08110622 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,04418375 0,08102552 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,04418375 0,08094498 ! exocrine system development GO:0035272 10 10 0,000 0,04418375 0,08086459 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,04418375 0,08078437 ! embryo implantation GO:0007566 11 10 0,000 0,04418375 0,08070431 ! regulation of protein binding GO:0043393 11 10 0,000 0,04418375 0,0806244 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,04418375 0,08054466 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,04418375 0,08046507 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,04418375 0,08038563 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,04418375 0,08030636 ! protein export from nucleus GO:0006611 10 10 0,000 0,04418375 0,08022724 ! negative regulation of immune response GO:0050777 10 10 0,000 0,04418375 0,08014827 ! cytolysis GO:0019835 10 10 0,000 0,04418375 0,08006947 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,04418375 0,07999081 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,04418375 0,07991231 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,04418375 0,07983397 ! histone deacetylation GO:0016575 10 10 0,000 0,04418375 0,07975578 ! mRNA splice site selection GO:0006376 11 10 0,000 0,04418375 0,07967774 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,04418375 0,07959985 ! gland morphogenesis GO:0022612 10 10 0,000 0,04418375 0,07952212 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,04418375 0,07944453 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,04418375 0,0793671 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,04418375 0,07928982 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,04418375 0,07921269 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,04418375 0,07913571 ! regulation of epidermis development GO:0045682 10 10 0,000 0,04418375 0,07905888 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,04418375 0,0789822 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,04418375 0,07890567 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,04418375 0,07882928 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,04418375 0,07875304 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,04418375 0,07867695 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,04418375 0,07860101 ! nerve development GO:0021675 10 10 0,000 0,04418375 0,07852521 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,04418375 0,07844956 ! gut development GO:0048565 10 10 0,000 0,04418375 0,07837406 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,04418375 0,0782987 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,04418375 0,07822348 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,04418375 0,07814841 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,04418375 0,07807349 ! protein stabilization GO:0050821 10 10 0,000 0,04418375 0,0779987 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,04556005 0,08035137 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,046646 0,08218794 ! regulation of protein modification process GO:0031399 79 78 1,000 0,04774155 0,0840379 ! protein secretion GO:0009306 11 11 0,000 0,04849675 0,08528579 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04849675 0,08520448 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04849675 0,08512334 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04849675 0,08504234 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04849675 0,08496151 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04849675 0,08488082 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04849675 0,08480029 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04849675 0,08471991 ! skin development GO:0043588 11 11 0,000 0,04849675 0,08463968 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04849675 0,08455961 ! signal complex assembly GO:0007172 11 11 0,000 0,04849675 0,08447968 ! microtubule-based transport GO:0010970 11 11 0,000 0,04849675 0,08439991 ! peroxisomal transport GO:0043574 11 11 0,000 0,04849675 0,08432029 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04849675 0,08424081 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,04849675 0,08416149 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,04849675 0,08408232 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,04849675 0,08400329 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04849675 0,08392442 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04849675 0,08384569 ! T cell proliferation GO:0042098 11 11 0,000 0,04849675 0,08376711 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04849675 0,08368867 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04849675 0,08361039 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04849675 0,08353225 ! spinal cord development GO:0021510 11 11 0,000 0,04849675 0,08345425 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04849675 0,0833764 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04849675 0,0832987 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04849675 0,08322114 ! digestive system process GO:0022600 11 11 0,000 0,04849675 0,08314373 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04849675 0,08306645 ! fucose metabolic process GO:0006004 11 11 0,000 0,04849675 0,08298933 ! membrane budding GO:0006900 11 11 0,000 0,04849675 0,08291234 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04849675 0,0828355 ! monoamine transport GO:0015844 11 11 0,000 0,04849675 0,0827588 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04849675 0,08268224 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04849675 0,08260583 ! body fluid secretion GO:0007589 11 11 0,000 0,04849675 0,08252955 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04849675 0,08245342 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04849675 0,08237742 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04849675 0,08230157 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04849675 0,08222586 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04849675 0,08215028 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04849675 0,08207484 ! oogenesis GO:0048477 11 11 0,000 0,04849675 0,08199955 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04849675 0,08192439 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04849675 0,08184936 ! vitamin transport GO:0051180 11 11 0,000 0,04849675 0,08177448 ! muscle maintenance GO:0046716 12 11 0,000 0,04849675 0,08169973 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04849675 0,08162512 ! hindbrain development GO:0030902 11 11 0,000 0,04849675 0,08155064 ! steroid catabolic process GO:0006706 11 11 0,000 0,04849675 0,0814763 ! endocrine process GO:0050886 11 11 0,000 0,04849675 0,0814021 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04849675 0,08132803 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04849675 0,0812541 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04849675 0,08118029 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04849675 0,08110663 ! nuclear transport GO:0051169 79 79 1,000 0,0488466 0,08161766 GO:0006913|nucleocytoplasmic transport, ! MAPKKK cascade GO:0000165 82 81 1,000 0,05108477 0,08528011 ! lymphocyte activation GO:0046649 82 81 1,000 0,05108477 0,08520293 ! translational initiation GO:0006413 12 12 0,000 0,05279091 0,08796894 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,05279091 0,08788947 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,05279091 0,08781015 ! initiation of viral infection GO:0019059 12 12 0,000 0,05279091 0,08773097 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,05279091 0,08765193 ! iron ion transport GO:0006826 13 12 0,000 0,05279091 0,08757304 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,05279091 0,08749429 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,05279091 0,08741567 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,05279091 0,0873372 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,05279091 0,08725887 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,05279091 0,08718069 ! collagen metabolic process GO:0032963 12 12 0,000 0,05279091 0,08710264 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,05279091 0,08702473 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,05279091 0,08694696 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,05279091 0,08686933 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,05279091 0,08679183 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,05279091 0,08671448 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,05279091 0,08663726 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,05279091 0,08656018 ! actomyosin structure organization GO:0031032 12 12 0,000 0,05279091 0,08648324 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,05279091 0,08640643 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,05279091 0,08632977 ! retinoid metabolic process GO:0001523 12 12 0,000 0,05279091 0,08625323 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,05279091 0,08617683 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,05279091 0,08610057 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,05279091 0,08602444 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,05279091 0,08594845 ! acute-phase response GO:0006953 12 12 0,000 0,05279091 0,08587259 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,05279091 0,08579687 ! vacuolar transport GO:0007034 12 12 0,000 0,05279091 0,08572127 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,05279091 0,08564581 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,05279091 0,08557049 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,05279091 0,08549529 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,05279091 0,08542023 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,05279091 0,0853453 ! male gonad development GO:0008584 12 12 0,000 0,05279091 0,0852705 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,05279091 0,08519584 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,05279091 0,0851213 ! renal system process GO:0003014 12 12 0,000 0,05279091 0,08504689 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,05279091 0,08497262 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,05279091 0,08489847 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,05279091 0,08482445 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,05279091 0,08475056 ! pallium development GO:0021543 13 12 0,000 0,05279091 0,0846768 ! cell fate determination GO:0001709 12 12 0,000 0,05279091 0,08460317 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,05279091 0,08452967 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,05279091 0,08445629 ! somitogenesis GO:0001756 13 12 0,000 0,05279091 0,08438304 ! G1 phase GO:0051318 13 12 0,000 0,05279091 0,08430992 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,05279091 0,08423692 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,05279091 0,08416405 ! detection of light stimulus GO:0009583 13 12 0,000 0,05279091 0,08409131 ! synaptogenesis GO:0007416 12 12 0,000 0,05279091 0,08401869 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,05279091 0,0839462 ! hormone transport GO:0009914 12 12 0,000 0,05279091 0,08387383 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,05279091 0,08380159 ! heme biosynthetic process GO:0006783 12 12 0,000 0,05279091 0,08372947 ! spermatid differentiation GO:0048515 13 12 0,000 0,05279091 0,08365748 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,05279091 0,08358561 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,05279091 0,08351386 ! neural tube closure GO:0001843 13 12 0,000 0,05279091 0,08344223 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,05279091 0,08337073 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,05279091 0,08329935 ! regulation of cellular localization GO:0060341 86 85 1,000 0,05567066 0,08776819 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,05567066 0,08769318 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,05683937 0,08945769 GO:0006644|phospholipid metabolic process, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,05706631 0,08973824 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,05706631 0,08966174 ! phenol metabolic process GO:0018958 13 13 0,000 0,05706631 0,08958536 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,05706631 0,08950912 ! gluconeogenesis GO:0006094 13 13 0,000 0,05706631 0,08943301 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,05706631 0,08935702 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,05706631 0,08928117 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,05706631 0,08920544 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,05706631 0,08912985 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,05706631 0,08905438 ! regeneration GO:0031099 13 13 0,000 0,05706631 0,08897903 ! keratinization GO:0031424 13 13 0,000 0,05706631 0,08890382 ! post-embryonic development GO:0009791 14 13 0,000 0,05706631 0,08882873 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,05706631 0,08875377 ! patterning of blood vessels GO:0001569 13 13 0,000 0,05706631 0,08867894 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,05706631 0,08860423 ! regulation of innate immune response GO:0045088 13 13 0,000 0,05706631 0,08852964 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,05706631 0,08845519 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,05706631 0,08838085 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,05706631 0,08830665 ! autophagy GO:0006914 13 13 0,000 0,05706631 0,08823256 ! receptor metabolic process GO:0043112 14 13 0,000 0,05706631 0,08815861 ! actin filament bundle formation GO:0051017 13 13 0,000 0,05706631 0,08808477 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,05706631 0,08801106 ! ureteric bud development GO:0001657 13 13 0,000 0,05706631 0,08793747 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,05706631 0,08786401 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,05706631 0,08779067 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,05706631 0,08771745 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,05706631 0,08764435 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,05706631 0,08757137 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,05706631 0,08749852 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,05706631 0,08742578 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,05706631 0,08735317 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,05706631 0,08728068 ! vasodilation GO:0042311 14 13 0,000 0,05706631 0,08720831 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,05706631 0,08713605 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,05706631 0,08706392 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,05706631 0,08699191 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,05706631 0,08692001 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,05706631 0,08684824 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,05706631 0,08677658 ! immunoglobulin production GO:0002377 13 13 0,000 0,05706631 0,08670504 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,05706631 0,08663362 ! cell-cell junction organization GO:0045216 13 13 0,000 0,05706631 0,08656232 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,05706631 0,08649113 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,05706631 0,08642006 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,05706631 0,08634911 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,05706631 0,08627827 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,05706631 0,08620756 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,05706631 0,08613695 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,05706631 0,08606646 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,05706631 0,08599609 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,05706631 0,08592583 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,05706631 0,08585569 ! blastocyst development GO:0001824 13 13 0,000 0,05706631 0,08578566 ! telomere organization GO:0032200 13 13 0,000 0,05706631 0,08571574 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,05706631 0,08564594 ! regulation of amine transport GO:0051952 13 13 0,000 0,05706631 0,08557625 ! neuron fate commitment GO:0048663 14 14 0,000 0,06132304 0,09188485 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,06132304 0,09181021 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,06132304 0,09173569 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,06132304 0,09166129 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,06132304 0,09158701 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,06132304 0,09151285 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,06132304 0,09143881 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,06132304 0,09136489 ! protein amino acid acylation GO:0043543 14 14 0,000 0,06132304 0,09129109 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,06132304 0,09121741 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,06132304 0,09114384 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,06132304 0,0910704 ! vesicle docking GO:0048278 14 14 0,000 0,06132304 0,09099707 ! superoxide metabolic process GO:0006801 15 14 0,000 0,06132304 0,09092387 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,06132304 0,09085078 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,06132304 0,0907778 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,06132304 0,09070495 ! hair cycle GO:0042633 14 14 0,000 0,06132304 0,09063221 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,06132304 0,09055959 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,06132304 0,09048708 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,06132304 0,09041469 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,06132304 0,09034242 ! lysosome organization GO:0007040 14 14 0,000 0,06132304 0,09027026 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,06132304 0,09019822 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,06132304 0,09012629 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,06132304 0,09005447 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,06132304 0,08998277 ! primary neural tube formation GO:0014020 15 14 0,000 0,06132304 0,08991119 ! peptide cross-linking GO:0018149 14 14 0,000 0,06132304 0,08983972 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,06132304 0,08976836 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,06132304 0,08969712 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,06132304 0,08962598 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,06132304 0,08955496 ! formation of primary germ layer GO:0001704 14 14 0,000 0,06132304 0,08948406 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,06132304 0,08941326 ! collagen fibril organization GO:0030199 14 14 0,000 0,06132304 0,08934258 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,06132304 0,08927201 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,06132304 0,08920155 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,06132304 0,0891312 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,06132304 0,08906097 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,06132304 0,08899084 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,06132304 0,08892082 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,06132304 0,08885092 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,06132304 0,08878112 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,06403105 0,0926289 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,06556117 0,09476803 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,06556117 0,09469376 ! positive regulation of ossification GO:0045778 15 15 0,000 0,06556117 0,0946196 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,06556117 0,09454557 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,06556117 0,09447165 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,06556117 0,09439784 ! response to vitamin GO:0033273 15 15 0,000 0,06556117 0,09432415 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,06556117 0,09425057 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,06556117 0,09417711 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,06556117 0,09410377 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,06556117 0,09403053 ! ovarian follicle development GO:0001541 15 15 0,000 0,06556117 0,09395741 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,06556117 0,09388441 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,06556117 0,09381152 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,06556117 0,09373874 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,06556117 0,09366607 ! heme metabolic process GO:0042168 15 15 0,000 0,06556117 0,09359352 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,06556117 0,09352108 ! chromosome condensation GO:0030261 15 15 0,000 0,06556117 0,09344875 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,06556117 0,09337653 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,06556117 0,09330443 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,06556117 0,09323243 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,06556117 0,09316055 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,06556117 0,09308878 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,06556117 0,09301712 ! phospholipid transport GO:0015914 15 15 0,000 0,06556117 0,09294557 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,06556117 0,09287412 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,06556117 0,09280279 ! glutathione metabolic process GO:0006749 16 15 0,000 0,06556117 0,09273157 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,06556117 0,09266046 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,06556117 0,09258945 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,06556117 0,09251856 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,06556117 0,09244777 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,06556117 0,09237709 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,06556117 0,09230652 ! protein homooligomerization GO:0051260 15 15 0,000 0,06556117 0,09223606 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,06556117 0,0921657 ! regulation of cell growth GO:0001558 97 96 1,000 0,06898944 0,09691124 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06978078 0,09794819 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06978078 0,09787365 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06978078 0,09779922 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,06978078 0,0977249 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,06978078 0,0976507 ! learning GO:0007612 16 16 0,000 0,06978078 0,09757661 ! circadian rhythm GO:0007623 16 16 0,000 0,06978078 0,09750263 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,06978078 0,09742877 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,06978078 0,09735501 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,06978078 0,09728137 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,06978078 0,09720784 ! vesicle targeting GO:0006903 17 16 0,000 0,06978078 0,09713442 ! segmentation GO:0035282 17 16 0,000 0,06978078 0,09706111 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06978078 0,09698791 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06978078 0,09691482 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06978078 0,09684185 ! positive regulation of cell development GO:0010720 16 16 0,000 0,06978078 0,09676898 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06978078 0,09669622 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06978078 0,09662357 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06978078 0,09655103 ! cell fate specification GO:0001708 16 16 0,000 0,06978078 0,0964786 ! pentose metabolic process GO:0019321 16 16 0,000 0,06978078 0,09640627 ! fatty acid transport GO:0015908 16 16 0,000 0,06978078 0,09633406 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06978078 0,09626195 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06978078 0,09618996 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06978078 0,09611806 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06978078 0,09604628 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06978078 0,09597461 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06978078 0,09590304 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06978078 0,09583157 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06978078 0,09576022 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,06978078 0,09568897 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,06978078 0,09561782 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06978078 0,09554678 ! regulation of coagulation GO:0050818 17 16 0,000 0,06978078 0,09547585 ! endocytosis GO:0006897 99 98 1,000 0,07151561 0,0977769 GO:0010324|membrane invagination, ! blood circulation GO:0008015 99 98 1,000 0,07151561 0,09770442 GO:0003013|circulatory system process, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,07398194 0,10099905 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,07398194 0,10092429 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,07398194 0,10084964 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,07398194 0,10077511 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,07398194 0,10070068 ! leukocyte adhesion GO:0007159 17 17 0,000 0,07398194 0,10062636 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,07398194 0,10055215 ! sensory perception of smell GO:0007608 17 17 0,000 0,07398194 0,10047805 ! glucose transport GO:0015758 17 17 0,000 0,07398194 0,10040406 ! cell junction assembly GO:0034329 18 17 0,000 0,07398194 0,10033018 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,07398194 0,10025641 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,07398194 0,10018275 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,07398194 0,10010919 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,07398194 0,10003574 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,07398194 0,0999624 ! neural crest cell development GO:0014032 19 17 0,000 0,07398194 0,09988917 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,07398194 0,09981605 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,07398194 0,09974303 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,07398194 0,09967012 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,07398194 0,09959731 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,07398194 0,09952461 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,07398194 0,09945202 ! pigmentation GO:0043473 17 17 0,000 0,07398194 0,09937953 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,07398194 0,09930715 ! adult locomotory behavior GO:0008344 17 17 0,000 0,07398194 0,09923487 ! embryonic organ development GO:0048568 17 17 0,000 0,07398194 0,0991627 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,07398194 0,09909064 ! liver development GO:0001889 17 17 0,000 0,07398194 0,09901868 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,07407213 0,09906744 ! response to other organism GO:0051707 101 100 1,000 0,07407213 0,0989956 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,07816474 0,10438958 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,07816474 0,10431399 ! meiosis I GO:0007127 18 18 0,000 0,07816474 0,10423851 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,07816474 0,10416314 ! membrane docking GO:0022406 18 18 0,000 0,07816474 0,10408787 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,07816474 0,10401272 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,07816474 0,10393768 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,07816474 0,10386274 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,07816474 0,10378791 ! hexose transport GO:0008645 18 18 0,000 0,07816474 0,10371319 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,07816474 0,10363857 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,07816474 0,10356407 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,07816474 0,10348967 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,07816474 0,10341538 ! ceramide metabolic process GO:0006672 18 18 0,000 0,07816474 0,10334119 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,07816474 0,10326711 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,07816474 0,10319314 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,07816474 0,10311927 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,07816474 0,10304551 ! BMP signaling pathway GO:0030509 18 18 0,000 0,07816474 0,10297185 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,07816474 0,1028983 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,07816474 0,10282485 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,07816474 0,10275151 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,08232926 0,10814884 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,08232926 0,10807181 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,08232926 0,10799489 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,08232926 0,10791808 ! feeding behavior GO:0007631 19 19 0,000 0,08232926 0,10784138 ! peroxisome organization GO:0007031 19 19 0,000 0,08232926 0,10776479 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,08232926 0,1076883 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,08232926 0,10761193 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,08232926 0,10753566 ! metanephros development GO:0001656 19 19 0,000 0,08232926 0,1074595 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,08232926 0,10738345 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,08232926 0,10730751 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,08232926 0,10723167 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,08232926 0,10715594 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,08232926 0,10708032 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,08232926 0,10700481 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,08232926 0,1069294 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,08232926 0,1068541 ! eye morphogenesis GO:0048592 19 19 0,000 0,08232926 0,1067789 ! placenta development GO:0001890 19 19 0,000 0,08232926 0,10670381 ! response to heat GO:0009408 19 19 0,000 0,08232926 0,10662882 ! vesicle localization GO:0051648 20 19 0,000 0,08232926 0,10655395 ! regulation of muscle development GO:0048634 21 20 0,000 0,08647556 0,11184172 ! negative regulation of binding GO:0051100 21 20 0,000 0,08647556 0,11176329 ! organic ether metabolic process GO:0018904 20 20 0,000 0,08647556 0,11168497 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,08647556 0,11160676 ! neural tube development GO:0021915 21 20 0,000 0,08647556 0,11152866 ! nucleus organization GO:0006997 20 20 0,000 0,08647556 0,11145067 ! phagocytosis GO:0006909 21 20 0,000 0,08647556 0,11137279 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,08647556 0,11129501 ! protein targeting to membrane GO:0006612 22 20 0,000 0,08647556 0,11121735 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,08647556 0,11113979 ! chromatin remodeling GO:0006338 20 20 0,000 0,08647556 0,11106234 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,08647556 0,110985 ! lipid oxidation GO:0034440 20 20 0,000 0,08647556 0,11090776 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,08647556 0,11083064 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,08647556 0,11075362 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,08647556 0,11067671 ! single fertilization GO:0007338 21 20 0,000 0,08647556 0,1105999 ! regulation of B cell activation GO:0050864 20 20 0,000 0,08647556 0,1105232 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,09060373 0,11571911 ! mRNA catabolic process GO:0006402 21 21 0,000 0,09060373 0,11563897 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,09060373 0,11555895 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,09060373 0,11547903 ! Notch signaling pathway GO:0007219 22 21 0,000 0,09060373 0,11539922 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,09060373 0,11531953 ! organic anion transport GO:0015711 21 21 0,000 0,09060373 0,11523994 ! cholesterol transport GO:0030301 21 21 0,000 0,09060373 0,11516047 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,09060373 0,1150811 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,09060373 0,11500184 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,09060373 0,1149227 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,09060373 0,11484366 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,09060373 0,11476473 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,09060373 0,1146859 ! regulation of proteolysis GO:0030162 21 21 0,000 0,09060373 0,11460719 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,09060373 0,11452858 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,09471385 0,11964196 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,09471385 0,11956001 ! sister chromatid segregation GO:0000819 22 22 0,000 0,09471385 0,11947818 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,09471385 0,11939646 ! regulation of ion transport GO:0043269 22 22 0,000 0,09471385 0,11931485 ! odontogenesis GO:0042476 22 22 0,000 0,09471385 0,11923335 ! cell junction organization GO:0034330 23 22 0,000 0,09471385 0,11915196 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,09471385 0,11907068 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,09471385 0,11898952 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,09471385 0,11890846 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,09471385 0,11882752 ! ovulation cycle process GO:0022602 22 22 0,000 0,09471385 0,11874668 ! spindle organization GO:0007051 22 22 0,000 0,09471385 0,11866596 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,09471385 0,11858534 ! cell chemotaxis GO:0060326 23 22 0,000 0,09471385 0,11850483 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,09471385 0,11842444 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,09471385 0,11834415 ! male sex differentiation GO:0046661 22 22 0,000 0,09471385 0,11826397 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,09471385 0,1181839 ! biopolymer methylation GO:0043414 22 22 0,000 0,09471385 0,11810394 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,09471385 0,11802408 ! detection of external stimulus GO:0009581 23 22 0,000 0,09471385 0,11794434 ! neuron migration GO:0001764 22 22 0,000 0,09471385 0,1178647 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,09471385 0,11778517 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,09471385 0,11770575 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,09471385 0,11762643 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,09471385 0,11754722 ! aerobic respiration GO:0009060 22 22 0,000 0,09471385 0,11746812 ! cytokine production GO:0001816 22 22 0,000 0,09471385 0,11738912 ! cytokinesis GO:0000910 23 22 0,000 0,09471385 0,11731023 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,09471385 0,11723144 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,09880598 0,12221438 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,09880598 0,12213241 ! viral infectious cycle GO:0019058 23 23 0,000 0,09880598 0,12205055 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,09880598 0,12196881 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,09880598 0,12188717 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,09880598 0,12180564 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,09880598 0,12172422 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,09880598 0,1216429 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,09880598 0,1215617 ! endocrine system development GO:0035270 23 23 0,000 0,09880598 0,12148061 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,09880598 0,12139962 ! female gonad development GO:0008585 23 23 0,000 0,09880598 0,12131874 ! lipid homeostasis GO:0055088 23 23 0,000 0,09880598 0,12123797 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,09880598 0,1211573 ! gliogenesis GO:0042063 24 24 0,000 0,10288022 0,12606931 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,10288022 0,12598554 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,10288022 0,12590188 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,10288022 0,12581834 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,10288022 0,12573491 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,10288022 0,12565158 ! ovulation cycle GO:0042698 24 24 0,000 0,10288022 0,12556837 ! fertilization GO:0009566 25 24 0,000 0,10288022 0,12548527 ! maintenance of protein location GO:0045185 25 24 0,000 0,10288022 0,12540227 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,10288022 0,12531939 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,10288022 0,12523662 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,10288022 0,12515395 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,10693662 0,13000277 ! negative regulation of secretion GO:0051048 26 25 0,000 0,10693662 0,12991707 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,10693662 0,12983148 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,10693662 0,12974601 ! cellular component disassembly GO:0022411 26 25 0,000 0,10693662 0,12966065 ! endosome transport GO:0016197 25 25 0,000 0,10693662 0,12957541 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,10693662 0,12949027 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,10693662 0,12940525 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,10693662 0,12932034 ! excretion GO:0007588 25 25 0,000 0,10693662 0,12923554 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,10693662 0,12915085 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,10693662 0,12906627 ! gastrulation GO:0007369 25 25 0,000 0,10693662 0,1289818 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,10693662 0,12889744 ! regulation of endocytosis GO:0030100 25 25 0,000 0,10693662 0,1288132 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,10693662 0,12872906 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,10693662 0,12864503 ! positive regulation of binding GO:0051099 27 26 0,000 0,11097527 0,13341646 ! positive regulation of defense response GO:0031349 26 26 0,000 0,11097527 0,13332949 ! glycolysis GO:0006096 26 26 0,000 0,11097527 0,13324263 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,11097527 0,13315588 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,11097527 0,13306925 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,11097527 0,13298272 ! cellular defense response GO:0006968 26 26 0,000 0,11097527 0,13289632 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,11097527 0,13281002 ! regulation of protein secretion GO:0050708 26 26 0,000 0,11097527 0,13272384 ! germ cell development GO:0007281 27 26 0,000 0,11097527 0,13263776 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,11097527 0,1325518 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,11097527 0,13246595 ! maintenance of location in cell GO:0051651 27 26 0,000 0,11097527 0,13238021 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,11499625 0,13708803 ! learning or memory GO:0007611 28 27 0,000 0,11499625 0,13699941 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,11499625 0,13691091 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,11499625 0,13682252 ! peptide metabolic process GO:0006518 29 27 0,000 0,11499625 0,13673425 ! mesenchymal cell development GO:0014031 29 27 0,000 0,11499625 0,13664609 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! defense response to bacterium GO:0042742 27 27 0,000 0,11499625 0,13655805 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,11499625 0,13647011 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,11499625 0,1363823 ! cell growth GO:0016049 27 27 0,000 0,11499625 0,13629459 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,11899962 0,14094878 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,11899962 0,14085826 GO:0007254|JNK cascade, ! carbohydrate transport GO:0008643 28 28 0,000 0,11899962 0,14076785 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,11899962 0,14067755 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,11899962 0,14058737 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,11899962 0,14049731 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,11899962 0,14040737 ! histone modification GO:0016570 28 28 0,000 0,11899962 0,14031753 ! developmental growth GO:0048589 28 28 0,000 0,11899962 0,14022782 ! cartilage development GO:0051216 29 28 0,000 0,11899962 0,14013821 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,12298547 0,1447396 ! leukocyte migration GO:0050900 30 29 0,000 0,12298547 0,14464724 ! antigen processing and presentation GO:0019882 29 29 0,000 0,12298547 0,14455499 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,12298547 0,14446285 ! tRNA processing GO:0008033 29 29 0,000 0,12298547 0,14437084 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,12298547 0,14427894 ! covalent chromatin modification GO:0016569 29 29 0,000 0,12298547 0,14418716 ! adult behavior GO:0030534 30 29 0,000 0,12298547 0,1440955 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,12298547 0,14400395 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,12298547 0,14391252 ! transition metal ion transport GO:0000041 31 30 0,000 0,12695386 0,14846191 ! RNA catabolic process GO:0006401 30 30 0,000 0,12695386 0,14836776 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,12695386 0,14827374 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,12695386 0,14817984 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,12695386 0,14808605 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,12695386 0,14799239 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,12695386 0,14789884 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,12695386 0,14780541 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,12695386 0,1477121 ! response to temperature stimulus GO:0009266 30 30 0,000 0,12695386 0,1476189 ! regulation of ossification GO:0030278 30 30 0,000 0,12695386 0,14752583 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,12695386 0,14743287 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,12695386 0,14734003 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,12695386 0,1472473 ! vesicle organization GO:0016050 30 30 0,000 0,12695386 0,14715469 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,12695386 0,1470622 ! regulation of translational initiation GO:0006446 31 31 0,000 0,13090487 0,15154377 ! membrane fusion GO:0006944 31 31 0,000 0,13090487 0,15144864 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,13090487 0,15135362 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,13090487 0,15125873 ! ion transmembrane transport GO:0034220 31 31 0,000 0,13090487 0,15116396 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,13090487 0,1510693 ! digestion GO:0007586 31 31 0,000 0,13090487 0,15097477 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,13090487 0,15088035 ! regulation of heart contraction GO:0008016 31 31 0,000 0,13090487 0,15078605 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,13090487 0,15069187 ! camera-type eye development GO:0043010 31 31 0,000 0,13090487 0,1505978 ! extracellular matrix organization GO:0030198 31 31 0,000 0,13090487 0,15050385 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,13090487 0,15041002 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,13090487 0,15031631 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,13090487 0,15022271 ! cell redox homeostasis GO:0045454 32 32 0,000 0,13483858 0,15464063 ! glucose catabolic process GO:0006007 32 32 0,000 0,13483858 0,15454446 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,13483858 0,15444841 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,13483858 0,15435248 ! cell maturation GO:0048469 32 32 0,000 0,13483858 0,15425667 ! nuclear export GO:0051168 32 32 0,000 0,13483858 0,15416098 ! kidney development GO:0001822 32 32 0,000 0,13483858 0,1540654 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,13483858 0,15396995 ! maintenance of location GO:0051235 33 32 0,000 0,13483858 0,15387461 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,13875505 0,15824601 ! amino acid transport GO:0006865 33 33 0,000 0,13875505 0,15814815 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,13875505 0,15805041 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,13875505 0,15795278 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,13875505 0,15785528 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,13875505 0,1577579 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,13875505 0,15766064 ! regulation of actin filament length GO:0030832 34 34 0,000 0,14265436 0,16199137 ! response to metal ion GO:0010038 34 34 0,000 0,14265436 0,16189162 ! muscle cell differentiation GO:0042692 35 34 0,000 0,14265436 0,16179199 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,14265436 0,16169249 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,14265436 0,16159311 ! secondary metabolic process GO:0019748 34 34 0,000 0,14265436 0,16149385 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,14265436 0,16139471 ! detection of stimulus GO:0051606 36 34 0,000 0,14265436 0,1612957 ! acute inflammatory response GO:0002526 35 35 0,000 0,14653659 0,16558365 ! regulation of cellular component size GO:0032535 35 35 0,000 0,14653659 0,16548219 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,14653659 0,16538085 ! mesoderm development GO:0007498 35 35 0,000 0,14653659 0,16527964 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,14653659 0,16517855 GO:0048609|reproductive process in a multicellular organism, ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,14653659 0,16507759 ! regulation of immune effector process GO:0002697 35 35 0,000 0,14653659 0,16497674 ! hydrogen transport GO:0006818 36 36 0,000 0,1504018 0,16922498 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,1504018 0,16912173 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,1504018 0,16901861 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,1504018 0,16891561 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,1504018 0,16881274 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,1504018 0,16870999 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,1504018 0,16860737 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,1504018 0,16850487 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,1504018 0,1684025 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,1504018 0,16830025 ! gonad development GO:0008406 36 36 0,000 0,1504018 0,16819813 ! activation of immune response GO:0002253 36 36 0,000 0,1504018 0,16809613 ! coagulation GO:0050817 39 36 0,000 0,1504018 0,16799425 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,15425007 0,17218829 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,15425007 0,17208406 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,15425007 0,17197996 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,15425007 0,17187598 ! eye development GO:0001654 37 37 0,000 0,15425007 0,17177213 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,15425007 0,1716684 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,15425007 0,1715648 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,15425007 0,17146132 ! positive regulation of secretion GO:0051047 39 38 0,000 0,15808146 0,17561431 ! neurotransmitter transport GO:0006836 40 38 0,000 0,15808146 0,17550852 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,15808146 0,17540285 ! exocytosis GO:0006887 40 38 0,000 0,15808146 0,17529731 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,15808146 0,1751919 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,15808146 0,17508662 ! chromosome segregation GO:0007059 38 38 0,000 0,15808146 0,17498146 ! urogenital system development GO:0001655 38 38 0,000 0,15808146 0,17487643 ! hexose catabolic process GO:0019320 38 38 0,000 0,15808146 0,17477153 ! RNA elongation GO:0006354 38 38 0,000 0,15808146 0,17466675 ! regulation of neurological system process GO:0031644 38 38 0,000 0,15808146 0,17456209 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,15808146 0,17445757 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,16189606 0,17856041 ! hemostasis GO:0007599 42 39 0,000 0,16189606 0,17845361 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,16189606 0,17834694 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,16189606 0,1782404 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,16189606 0,17813399 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,16189606 0,17802771 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,16189606 0,17792155 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,16189606 0,17781552 ! developmental maturation GO:0021700 39 39 0,000 0,16189606 0,17770961 ! limb development GO:0060173 39 39 0,000 0,16189606 0,17760383 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,16569393 0,18166205 ! DNA catabolic process GO:0006308 41 40 0,000 0,16569393 0,18155405 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,16569393 0,18144617 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,16569393 0,18133843 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,16947514 0,18536658 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,16947514 0,18525663 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,16947514 0,18514682 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,16947514 0,18503713 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,16947514 0,18492758 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,16947514 0,18481816 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,16947514 0,18470886 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,17323977 0,18870029 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,17323977 0,18858883 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,17323977 0,1884775 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,17323977 0,18836631 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,17323977 0,18825524 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,17323977 0,18814431 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,17323977 0,1880335 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,17323977 0,18792283 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,17323977 0,18781229 ! reproductive structure development GO:0048608 43 43 0,000 0,17698787 0,19176288 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,17698787 0,19165021 ! alcohol catabolic process GO:0046164 43 43 0,000 0,17698787 0,19153767 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,17698787 0,19142527 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,17698787 0,19131299 ! humoral immune response GO:0006959 44 44 0,000 0,18071954 0,19523218 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,18071954 0,19511781 ! mRNA transport GO:0051028 44 44 0,000 0,18071954 0,19500357 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,18071954 0,19488947 ! vitamin metabolic process GO:0006766 44 44 0,000 0,18071954 0,1947755 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,18071954 0,19466166 ! amine biosynthetic process GO:0009309 46 45 0,000 0,18443482 0,19854753 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,18443482 0,19843163 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,18443482 0,19831586 ! regulation of DNA binding GO:0051101 47 45 0,000 0,18443482 0,19820022 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,18443482 0,19808472 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,18443482 0,19796935 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,18443482 0,19785412 ! protein processing GO:0016485 45 45 0,000 0,18443482 0,19773902 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,1881338 0,20158756 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,1881338 0,20147042 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,1881338 0,20135342 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,1881338 0,20123656 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,1881338 0,20111984 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,19181654 0,20493791 ! regulation of blood pressure GO:0008217 48 47 0,000 0,19181654 0,20481917 ! sex differentiation GO:0007548 47 47 0,000 0,19181654 0,20470057 ! amine transport GO:0015837 47 47 0,000 0,19181654 0,20458211 ! rhythmic process GO:0048511 47 47 0,000 0,19181654 0,20446379 ! calcium ion transport GO:0006816 48 48 0,000 0,19548311 0,20825166 ! actin filament organization GO:0007015 50 48 0,000 0,19548311 0,20813136 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,19548311 0,20801119 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,19913359 0,21177334 ! divalent metal ion transport GO:0070838 49 49 0,000 0,19913359 0,21165121 ! response to bacterium GO:0009617 50 49 0,000 0,19913359 0,21152922 ! regulation of ligase activity GO:0051340 50 49 0,000 0,19913359 0,21140737 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,19913359 0,21128566 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,19913359 0,2111641 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,20276803 0,21489446 ! RNA transport GO:0050658 50 50 0,000 0,20276803 0,21477096 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,20276803 0,2146476 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,20276803 0,21452438 ! transcription initiation GO:0006352 50 50 0,000 0,20276803 0,2144013 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,20276803 0,21427837 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,2063865 0,21797726 ! positive regulation of immune response GO:0050778 51 51 0,000 0,2063865 0,21785242 ! rRNA metabolic process GO:0016072 51 51 0,000 0,2063865 0,21772772 GO:0006364|rRNA processing, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,2063865 0,21760316 ! protein maturation GO:0051604 51 51 0,000 0,2063865 0,21747874 ! RNA localization GO:0006403 52 52 0,000 0,20998908 0,2211485 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,20998908 0,2210222 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,20998908 0,22089605 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,20998908 0,22077004 ! sodium ion transport GO:0006814 53 53 0,000 0,21357583 0,22441292 ! tRNA metabolic process GO:0006399 53 53 0,000 0,21357583 0,22428505 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,21357583 0,22415732 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,21357583 0,22402974 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,21357583 0,22390231 ! hormone metabolic process GO:0042445 55 54 0,000 0,21714682 0,22751654 ! sulfur metabolic process GO:0006790 55 54 0,000 0,21714682 0,22738727 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,22070212 0,23097899 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,22070212 0,2308479 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,22424179 0,23441725 ! regulation of binding GO:0051098 60 57 0,000 0,22776589 0,23796629 ! ATP metabolic process GO:0046034 57 57 0,000 0,22776589 0,23783147 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,22776589 0,2376968 ! innate immune response GO:0045087 58 58 0,000 0,23127451 0,2412218 ! carboxylic acid transport GO:0046942 59 59 0,000 0,23476769 0,24472672 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,23476769 0,24458838 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,23476769 0,2444502 ! immune effector process GO:0002252 59 59 0,000 0,23476769 0,24431217 ! potassium ion transport GO:0006813 60 60 0,000 0,23824551 0,24779146 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,23824551 0,2476517 ! protein polymerization GO:0051258 65 60 0,000 0,23824551 0,2475121 ! cellular respiration GO:0045333 62 61 0,000 0,24170803 0,25096783 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,24170803 0,25082652 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,24170803 0,25068537 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,24170803 0,25054437 ! lipid transport GO:0006869 62 62 0,000 0,24515531 0,25397484 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,24515531 0,25383216 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,24515531 0,25368964 GO:0060429|epithelium development, ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,24515531 0,25354728 ! regulation of secretion GO:0051046 65 63 0,000 0,24858743 0,25695269 ! glucose metabolic process GO:0006006 63 63 0,000 0,24858743 0,25680865 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,24858743 0,25666478 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,24858743 0,25652107 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,25200445 0,25990162 ! regulation of hormone levels GO:0010817 66 65 0,000 0,25540642 0,26326288 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,25879342 0,26660496 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,25879342 0,26645602 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,25879342 0,26630725 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,26216551 0,26962669 ! muscle contraction GO:0006936 67 67 0,000 0,26216551 0,26947632 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,26552275 0,27277504 ! regulation of translation GO:0006417 69 69 0,000 0,2688652 0,27605491 ! regionalization GO:0003002 70 69 0,000 0,2688652 0,27590121 ! positive regulation of transport GO:0051050 71 70 0,000 0,27219293 0,27916059 ! growth GO:0040007 70 70 0,000 0,27219293 0,27900533 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,27219293 0,27885024 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,27550601 0,28208754 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,27550601 0,28193091 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,27550601 0,28177446 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,27550601 0,28161817 ! secretion by cell GO:0032940 75 72 0,000 0,27880448 0,28483185 ! muscle system process GO:0003012 72 72 0,000 0,27880448 0,28467405 ! regulation of cytokine production GO:0001817 72 72 0,000 0,27880448 0,28451642 ! electron transport chain GO:0022900 75 74 0,000 0,28535789 0,29104294 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,28535789 0,29088196 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,28861294 0,2940374 ! response to oxidative stress GO:0006979 76 75 0,000 0,28861294 0,29387495 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,28861294 0,29371267 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,29185365 0,29684673 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,29508006 0,2999628 ! microtubule-based movement GO:0007018 82 78 0,000 0,29829225 0,30306098 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,29829225 0,30289401 ! metal ion homeostasis GO:0055065 78 78 0,000 0,29829225 0,30272721 ! regulation of immune response GO:0050776 78 78 0,000 0,29829225 0,30256061 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,30467419 0,30886388 ! lipid catabolic process GO:0016042 82 81 0,000 0,30784405 0,31190577 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,31414189 0,31811181 ! ncRNA processing GO:0034470 83 83 0,000 0,31414189 0,31793712 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,31726998 0,32092676 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,32038425 0,32389917 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,32038425 0,32372159 ! hexose metabolic process GO:0019318 87 86 0,000 0,32348478 0,32667532 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,32964482 0,33271381 ! chemotaxis GO:0006935 90 89 0,000 0,33270445 0,33561812 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,33270445 0,33543452 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,33575057 0,33832056 ! brain development GO:0007420 91 90 0,000 0,33575057 0,33813568 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,33878322 0,34100354 ! DNA replication GO:0006260 91 91 0,000 0,33878322 0,3408174 ! visual perception GO:0007601 93 92 0,000 0,34180248 0,34366719 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,34180248 0,34347981 ! tissue morphogenesis GO:0048729 94 93 0,000 0,34480839 0,34631164 ! regulation of response to stress GO:0080134 97 94 0,000 0,34780101 0,34912705 ! pattern specification process GO:0007389 96 94 0,000 0,34780101 0,348937 ! epidermis development GO:0008544 94 94 0,000 0,34780101 0,34874715 ! cofactor metabolic process GO:0051186 95 94 0,000 0,34780101 0,34855751 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,35963977 0,36022614 ! regulation of system process GO:0044057 98 98 0,000 0,35963977 0,36003047 ! anti-apoptosis GO:0006916 100 99 0,000 0,36256681 0,36276365 ! ectoderm development GO:0007398 99 99 0,000 0,36256681 0,36256681