pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6554-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phospholipid dephosphorylation GO:0046839 12 5 3,000 4,633E-10 1,115E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,387E-09 1,668E-06 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 4,000 1,686E-09 1,352E-06 ! regulation of lipid kinase activity GO:0043550 13 7 3,000 3,228E-09 1,941E-06 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 3,228E-09 1,553E-06 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 3,000 6,44E-09 2,582E-06 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 6,44E-09 2,213E-06 ! negative regulation of cell migration GO:0030336 115 46 5,000 7,101E-09 2,136E-06 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 1,923E-08 5,14E-06 ! chloride transport GO:0006821 90 55 5,000 2,148E-08 5,168E-06 ! negative regulation of cell motion GO:0051271 134 55 5,000 2,148E-08 4,698E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 2,675E-08 5,364E-06 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 3,014E-08 5,578E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! inorganic anion transport GO:0015698 138 80 5,000 2,09E-07 3,592E-05 ! endothelial cell migration GO:0043542 28 17 3,000 2,142E-07 3,436E-05 ! inositol metabolic process GO:0006020 28 17 3,000 2,142E-07 3,221E-05 ! cardiac muscle tissue development GO:0048738 31 17 3,000 2,142E-07 3,032E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 3,104E-07 4,149E-05 ! male meiosis GO:0007140 7 6 2,000 6,039E-07 7,648E-05 ! nuclear migration GO:0007097 12 6 2,000 6,039E-07 7,265E-05 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 6,039E-07 6,919E-05 GO:0031272|regulation of pseudopodium assembly, ! response to UV GO:0009411 104 53 4,000 7,147E-07 7,817E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 7,856E-07 8,218E-05 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell migration GO:0030335 126 57 4,000 1,033E-06 1,035E-04 ! lipid modification GO:0030258 97 57 4,000 1,033E-06 9,937E-05 ! macrophage differentiation GO:0030225 11 7 2,000 1,054E-06 9,758E-05 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 3,000 1,117E-06 9,952E-05 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,317E-06 1,131E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 1,317E-06 1,092E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,337E-06 1,072E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,683E-06 1,306E-04 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 1,795E-06 1,349E-04 ! positive regulation of cell motion GO:0051272 146 64 4,000 1,848E-06 1,347E-04 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 2,39E-06 1,692E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 2,519E-06 1,732E-04 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 3,324E-06 2,222E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 3,59E-06 2,335E-04 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 3,000 4,006E-06 2,537E-04 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 4,512E-06 2,784E-04 ! nucleus localization GO:0051647 19 11 2,000 4,926E-06 2,963E-04 ! regulation of protein stability GO:0031647 73 37 3,000 5,664E-06 3,324E-04 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 5,664E-06 3,245E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 6,552E-06 3,666E-04 ! mammary gland development GO:0030879 86 39 3,000 7,02E-06 3,839E-04 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 8,499E-06 4,544E-04 GO:0000725|recombinational repair, ! response to X-ray GO:0010165 25 13 2,000 8,499E-06 4,445E-04 ! polyol metabolic process GO:0019751 66 41 3,000 8,602E-06 4,403E-04 ! regulation of cell adhesion GO:0030155 212 89 4,000 9,453E-06 4,738E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,043E-05 5,122E-04 ! response to gamma radiation GO:0010332 28 14 2,000 1,079E-05 5,193E-04 ! double-strand break repair GO:0006302 81 44 3,000 1,145E-05 5,401E-04 ! response to insulin stimulus GO:0032868 95 46 3,000 1,369E-05 6,337E-04 ! filopodium assembly GO:0046847 32 16 2,000 1,653E-05 7,503E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,002E-05 8,921E-04 ! microspike assembly GO:0030035 36 17 2,000 2,002E-05 8,759E-04 ! regulation of DNA replication GO:0006275 101 56 3,000 3,009E-05 1,293E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,334E-05 1,407E-03 ! cell aging GO:0007569 44 21 2,000 3,88E-05 1,61E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 3,956E-05 1,613E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 4,224E-05 1,694E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 4,483E-05 1,768E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 4,483E-05 1,74E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 4,798E-05 1,832E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 5,144E-05 1,934E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 5,865E-05 2,171E-03 ! protein tetramerization GO:0051262 52 24 2,000 5,865E-05 2,138E-03 ! vasculogenesis GO:0001570 46 25 2,000 6,649E-05 2,388E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 6,649E-05 2,353E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 6,649E-05 2,319E-03 ! interaction with host GO:0051701 62 25 2,000 6,649E-05 2,285E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 8,418E-05 2,853E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 8,418E-05 2,813E-03 ! meiosis GO:0007126 121 74 3,000 9,026E-05 2,975E-03 GO:0051327|M phase of meiotic cell cycle, ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 9,406E-05 3,058E-03 ! meiotic cell cycle GO:0051321 122 75 3,000 9,512E-05 3,051E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 9,785E-05 3,098E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 9,785E-05 3,057E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 9,785E-05 3,018E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 9,785E-05 2,98E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 9,785E-05 2,943E-03 ! base conversion or substitution editing GO:0016553 5 5 1,000 9,785E-05 2,906E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 9,785E-05 2,871E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 9,785E-05 2,836E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,047E-04 2,998E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,047E-04 2,963E-03 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,346E-04 3,765E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 1,411E-04 3,903E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,411E-04 3,858E-03 ! male sex determination GO:0030238 15 6 1,000 1,465E-04 3,96E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,465E-04 3,916E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 1,465E-04 3,873E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,465E-04 3,831E-03 ! gland development GO:0048732 206 88 3,000 1,769E-04 4,576E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,849E-04 4,734E-03 ! regulation of cell cycle process GO:0010564 149 90 3,000 1,929E-04 4,885E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,046E-04 5,129E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 2,046E-04 5,076E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,046E-04 5,024E-03 ! mRNA stabilization GO:0048255 18 7 1,000 2,046E-04 4,973E-03 GO:0043489|RNA stabilization, ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 2,046E-04 4,924E-03 ! centrosome duplication GO:0051298 13 7 1,000 2,046E-04 4,875E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,046E-04 4,827E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,046E-04 4,78E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,046E-04 4,734E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,046E-04 4,689E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,046E-04 4,645E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 2,186E-04 4,914E-03 ! glycogen metabolic process GO:0005977 61 37 2,000 2,186E-04 4,869E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,188E-04 4,83E-03 ! glucan metabolic process GO:0044042 62 38 2,000 2,367E-04 5,178E-03 GO:0006073|cellular glucan metabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,374E-04 5,146E-03 ! leukocyte differentiation GO:0002521 202 96 3,000 2,472E-04 5,31E-03 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,572E-04 5,476E-03 ! interphase GO:0051325 213 98 3,000 2,675E-04 5,645E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,723E-04 5,697E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,723E-04 5,648E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,723E-04 5,599E-03 ! ER overload response GO:0006983 12 8 1,000 2,723E-04 5,552E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,723E-04 5,505E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 2,723E-04 5,459E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,723E-04 5,414E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,723E-04 5,37E-03 ! blastocyst growth GO:0001832 19 8 1,000 2,723E-04 5,326E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,723E-04 5,283E-03 ! cell cycle arrest GO:0007050 213 100 3,000 2,89E-04 5,562E-03 ! energy reserve metabolic process GO:0006112 74 43 2,000 3,424E-04 6,538E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,494E-04 6,619E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,494E-04 6,567E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 3,494E-04 6,516E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,494E-04 6,466E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 3,494E-04 6,417E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,494E-04 6,368E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,494E-04 6,32E-03 ! S phase GO:0051320 9 9 1,000 3,494E-04 6,273E-03 GO:0000084|S phase of mitotic cell cycle, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 4,183E-04 7,455E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,183E-04 7,4E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,358E-04 7,654E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,358E-04 7,598E-03 ! lung alveolus development GO:0048286 26 10 1,000 4,358E-04 7,544E-03 ! pathogenesis GO:0009405 13 10 1,000 4,358E-04 7,49E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 4,358E-04 7,437E-03 ! multicellular organism growth GO:0035264 18 10 1,000 4,358E-04 7,384E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 4,358E-04 7,333E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 4,358E-04 7,282E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,358E-04 7,231E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 4,358E-04 7,182E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 4,358E-04 7,133E-03 ! localization within membrane GO:0051668 20 10 1,000 4,358E-04 7,085E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 4,744E-04 7,661E-03 ! Notch signaling pathway GO:0007219 96 48 2,000 4,744E-04 7,61E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 4,744E-04 7,56E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,316E-04 8,414E-03 ! blood vessel remodeling GO:0001974 29 11 1,000 5,316E-04 8,359E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 5,316E-04 8,305E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,316E-04 8,251E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 5,316E-04 8,198E-03 ! oocyte differentiation GO:0009994 18 11 1,000 5,316E-04 8,146E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 5,316E-04 8,095E-03 ! regulation of cell projection organization GO:0031344 121 50 2,000 5,352E-04 8,099E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 5,674E-04 8,532E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 6,366E-04 9,513E-03 ! virus-host interaction GO:0019048 29 12 1,000 6,366E-04 9,454E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,366E-04 9,396E-03 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 6,366E-04 9,339E-03 GO:0050927|positive regulation of positive chemotaxis, ! entry into host cell GO:0030260 32 12 1,000 6,366E-04 9,282E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 6,366E-04 9,226E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 6,366E-04 9,171E-03 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 7,083E-04 0,0101432 ! aging GO:0007568 103 55 2,000 7,083E-04 0,01008318 ! nucleotide-excision repair GO:0006289 83 56 2,000 7,466E-04 0,01056716 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 7,508E-04 0,01056337 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,508E-04 0,01050196 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 7,508E-04 0,01044125 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,508E-04 0,01038125 ! regulation of mRNA stability GO:0043488 31 13 1,000 7,508E-04 0,01032193 ! establishment of organelle localization GO:0051656 109 59 2,000 8,697E-04 0,01188877 ! regulation of S phase GO:0033261 23 14 1,000 8,741E-04 0,01188173 ! regulation of mRNA processing GO:0050684 24 14 1,000 8,741E-04 0,01181498 ! regulation of RNA stability GO:0043487 32 14 1,000 8,741E-04 0,01174897 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,741E-04 0,0116837 ! regulation of protein complex assembly GO:0043254 117 61 2,000 9,584E-04 0,01274005 ! viral reproductive process GO:0022415 126 62 2,000 1,005E-03 0,01328402 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,006E-03 0,01323296 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,006E-03 0,01316105 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,006E-03 0,01308991 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,006E-03 0,01301953 ! regulation of mitosis GO:0007088 105 63 2,000 1,053E-03 0,0135444 GO:0051783|regulation of nuclear division, ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,148E-03 0,01469095 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,148E-03 0,01461322 ! auditory receptor cell differentiation GO:0042491 32 16 1,000 1,148E-03 0,01453631 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,148E-03 0,01446021 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,148E-03 0,01438489 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,148E-03 0,01431036 ! myeloid cell differentiation GO:0030099 111 65 2,000 1,153E-03 0,01429535 ! cell projection assembly GO:0030031 120 66 2,000 1,205E-03 0,01486541 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,258E-03 0,01544764 ! lung development GO:0030324 144 67 2,000 1,258E-03 0,01536923 ! gene silencing by RNA GO:0031047 36 17 1,000 1,298E-03 0,01577641 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,298E-03 0,01569713 ! viral reproduction GO:0016032 134 68 2,000 1,314E-03 0,01580141 ! negative regulation of cell size GO:0045792 134 69 2,000 1,37E-03 0,01640013 ! respiratory tube development GO:0030323 150 70 2,000 1,428E-03 0,0170109 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,458E-03 0,01727579 ! centrosome cycle GO:0007098 25 18 1,000 1,458E-03 0,01719111 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,458E-03 0,01710725 ! respiratory system development GO:0060541 153 72 2,000 1,549E-03 0,01809128 ! lipid phosphorylation GO:0046834 35 19 1,000 1,626E-03 0,0188963 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,626E-03 0,01880545 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,626E-03 0,01871547 GO:0030968|endoplasmic reticulum unfolded protein response, ! neuromuscular junction development GO:0007528 34 19 1,000 1,626E-03 0,01862635 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,626E-03 0,01853807 ! organelle localization GO:0051640 136 74 2,000 1,676E-03 0,01902061 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,803E-03 0,02036261 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,803E-03 0,02026746 ! cellular response to starvation GO:0009267 33 20 1,000 1,803E-03 0,02017319 ! ribosomal small subunit biogenesis GO:0042274 24 20 1,000 1,803E-03 0,0200798 ! inner ear receptor cell differentiation GO:0060113 37 20 1,000 1,803E-03 0,01998726 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,803E-03 0,01989558 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,803E-03 0,01980473 ! regulation of catabolic process GO:0009894 161 76 2,000 1,809E-03 0,01978715 ! protein oligomerization GO:0051259 139 78 2,000 1,949E-03 0,02121937 ! oogenesis GO:0048477 36 21 1,000 1,988E-03 0,02154937 ! positive regulation of locomotion GO:0040017 39 21 1,000 1,988E-03 0,02145273 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 41 21 1,000 1,988E-03 0,02135696 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,183E-03 0,02334031 ! regulation of chemotaxis GO:0050920 40 22 1,000 2,183E-03 0,02323703 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 2,183E-03 0,02313467 ! mechanoreceptor differentiation GO:0042490 40 22 1,000 2,183E-03 0,0230332 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,183E-03 0,02293262 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 2,183E-03 0,02283291 ! response to nutrient GO:0007584 125 82 2,000 2,248E-03 0,02341842 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,386E-03 0,02474109 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,386E-03 0,02463491 ! sex determination GO:0007530 47 23 1,000 2,386E-03 0,02452963 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,386E-03 0,02442525 ! negative regulation of growth GO:0045926 155 84 2,000 2,408E-03 0,02455094 ! response to unfolded protein GO:0006986 131 85 2,000 2,491E-03 0,02528431 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,597E-03 0,02625596 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,597E-03 0,0261461 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,597E-03 0,02603716 ! regulation of behavior GO:0050795 43 24 1,000 2,597E-03 0,02592912 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,597E-03 0,02582197 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,817E-03 0,02789461 ! myelination GO:0042552 45 25 1,000 2,817E-03 0,02778029 ! response to starvation GO:0042594 42 25 1,000 2,817E-03 0,0276669 ! negative regulation of cell development GO:0010721 73 25 1,000 2,817E-03 0,02755443 GO:0050768|negative regulation of neurogenesis, ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,817E-03 0,02744287 ! neuromuscular process controlling balance GO:0050885 60 25 1,000 2,817E-03 0,02733222 ! response to protein stimulus GO:0051789 149 91 2,000 3,022E-03 0,02920024 ! initiation of viral infection GO:0019059 57 26 1,000 3,046E-03 0,02931288 ! microtubule organizing center organization GO:0031023 39 26 1,000 3,046E-03 0,02919609 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 3,046E-03 0,02908023 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,046E-03 0,02896529 GO:0045936|negative regulation of phosphate metabolic process, ! blastocyst development GO:0001824 49 26 1,000 3,046E-03 0,02885126 ! neuron fate commitment GO:0048663 48 27 1,000 3,283E-03 0,03097362 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 3,283E-03 0,03085263 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,283E-03 0,03073258 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,283E-03 0,03061347 ! base-excision repair GO:0006284 41 27 1,000 3,283E-03 0,03049527 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 3,283E-03 0,03037798 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,283E-03 0,03026159 ! translational initiation GO:0006413 65 29 1,000 3,782E-03 0,03472726 ! regulation of pH GO:0006885 43 29 1,000 3,782E-03 0,03459521 ! response to organic cyclic substance GO:0014070 55 29 1,000 3,782E-03 0,03446417 ! tissue homeostasis GO:0001894 48 29 1,000 3,782E-03 0,03433412 GO:0048871|multicellular organismal homeostasis, ! ensheathment of neurons GO:0007272 57 30 1,000 4,043E-03 0,03657329 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 4,043E-03 0,03643631 ! regulation of B cell activation GO:0050864 50 30 1,000 4,043E-03 0,03630035 ! inner ear morphogenesis GO:0042472 47 31 1,000 4,313E-03 0,0385805 ! peripheral nervous system development GO:0007422 64 32 1,000 4,592E-03 0,04091629 ! gene silencing GO:0016458 65 32 1,000 4,592E-03 0,0407653 ! DNA damage checkpoint GO:0000077 71 33 1,000 4,878E-03 0,0431474 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,878E-03 0,04298935 ! negative regulation of protein transport GO:0051224 69 33 1,000 4,878E-03 0,04283245 ! mismatch repair GO:0006298 46 34 1,000 5,172E-03 0,04525132 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,474E-03 0,04772222 ! female gonad development GO:0008585 58 35 1,000 5,474E-03 0,04754994 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,474E-03 0,0473789 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,474E-03 0,04720908 ! DNA integrity checkpoint GO:0031570 75 36 1,000 5,785E-03 0,04970582 ! negative regulation of cell activation GO:0050866 65 36 1,000 5,785E-03 0,04952893 ! tissue remodeling GO:0048771 76 37 1,000 6,103E-03 0,05206693 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 6,103E-03 0,05188294 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,428E-03 0,05446107 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 6,428E-03 0,05426998 ! carbohydrate homeostasis GO:0033500 53 38 1,000 6,428E-03 0,05408022 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 6,428E-03 0,05389179 GO:0046660|female sex differentiation, ! erythrocyte homeostasis GO:0034101 64 38 1,000 6,428E-03 0,05370466 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,428E-03 0,05351883 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! ear morphogenesis GO:0042471 60 39 1,000 6,762E-03 0,05610246 ! regulation of action potential in neuron GO:0019228 73 39 1,000 6,762E-03 0,05590967 ! Rho protein signal transduction GO:0007266 74 39 1,000 6,762E-03 0,0557182 ! RNA modification GO:0009451 57 39 1,000 6,762E-03 0,05552804 ! cytokinesis GO:0000910 72 40 1,000 7,104E-03 0,05813287 ! regulation of T cell proliferation GO:0042129 71 41 1,000 7,453E-03 0,0607826 ! T cell differentiation GO:0030217 81 41 1,000 7,453E-03 0,06057726 ! regulation of T cell differentiation GO:0045580 70 41 1,000 7,453E-03 0,06037329 ! female gamete generation GO:0007292 61 41 1,000 7,453E-03 0,0601707 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 7,809E-03 0,06283949 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 8,173E-03 0,06555119 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 8,173E-03 0,06533341 ! B cell differentiation GO:0030183 107 44 1,000 8,545E-03 0,0680788 ! developmental growth GO:0048589 82 44 1,000 8,545E-03 0,06785412 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 8,924E-03 0,07063227 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 9,311E-03 0,07345073 ! vascular process in circulatory system GO:0003018 80 47 1,000 9,705E-03 0,07630871 ! mitochondrial transport GO:0006839 82 48 1,000 0,01010643 0,07920545 ! activation of caspase activity GO:0006919 84 48 1,000 0,01010643 0,07894829 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01010643 0,07869279 ! regulation of action potential GO:0001508 95 49 1,000 0,01051503 0,08161024 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,01051503 0,08134782 ! neuromuscular process GO:0050905 99 50 1,000 0,01093086 0,08429376 ! inner ear development GO:0048839 79 50 1,000 0,01093086 0,08402445 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01093086 0,08375685 ! viral infectious cycle GO:0019058 99 51 1,000 0,01135386 0,08672188 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01135386 0,08644744 ! regulation of cell shape GO:0008360 125 51 1,000 0,01135386 0,08617474 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01178399 0,08915809 ! positive regulation of growth GO:0045927 90 52 1,000 0,01178399 0,0888786 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,01178399 0,08860086 ! synapse organization GO:0050808 85 52 1,000 0,01178399 0,08832484 ! cell maturation GO:0048469 100 53 1,000 0,01222119 0,09131734 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01222119 0,09103463 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01266542 0,09405249 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01311664 0,09710347 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01311664 0,09680561 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,01311664 0,09650957 ! heart morphogenesis GO:0003007 97 55 1,000 0,01311664 0,09621533 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01357478 0,09927335 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01403982 0,10236305 ! muscle fiber development GO:0048747 112 57 1,000 0,01403982 0,1020538 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01403982 0,1017464 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01403982 0,10144086 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01451169 0,10453634 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01451169 0,10422429 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,01499036 0,1073417 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01567367 0,11190164 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01567367 0,11157057 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01567367 0,11124145 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01567367 0,11091427 ! neuron fate determination GO:0048664 7 5 0,000 0,01567367 0,11058901 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01567367 0,11026565 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01567367 0,10994417 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01567367 0,10962457 ! polyol transport GO:0015791 12 5 0,000 0,01567367 0,10930682 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01567367 0,1089909 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01567367 0,10867681 ! response to superoxide GO:0000303 10 5 0,000 0,01567367 0,10836452 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01567367 0,10805402 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01567367 0,10774529 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01567367 0,10743832 ! female meiosis GO:0007143 7 5 0,000 0,01567367 0,1071331 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01567367 0,10682961 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01567367 0,10652783 ! cobalt ion transport GO:0006824 11 5 0,000 0,01567367 0,10622775 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01567367 0,10592936 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01567367 0,10563264 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01567367 0,10533757 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01567367 0,10504416 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01567367 0,10475237 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01567367 0,10446219 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01567367 0,10417362 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01567367 0,10388664 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01567367 0,10360124 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01567367 0,1033174 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01567367 0,10303511 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01567367 0,10275436 ! negative chemotaxis GO:0050919 14 5 0,000 0,01567367 0,10247514 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01567367 0,10219743 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01567367 0,10192122 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01567367 0,1016465 ! behavioral response to pain GO:0048266 9 5 0,000 0,01567367 0,10137326 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01567367 0,10110148 ! Notch receptor processing GO:0007220 8 5 0,000 0,01567367 0,10083115 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01567367 0,10056227 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01567367 0,10029482 ! micturition GO:0060073 9 5 0,000 0,01567367 0,10002878 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01567367 0,09976416 ! copulation GO:0007620 9 5 0,000 0,01567367 0,09950093 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01567367 0,09923908 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01567367 0,09897861 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01567367 0,09871951 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01567367 0,09846175 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01567367 0,09820534 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01567367 0,09795026 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01567367 0,09769651 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01567367 0,09744406 ! grooming behavior GO:0007625 6 5 0,000 0,01567367 0,09719292 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01567367 0,09694306 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01567367 0,09669449 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01567367 0,09644719 ! response to protozoan GO:0001562 10 5 0,000 0,01567367 0,09620115 ! lymph vessel development GO:0001945 10 5 0,000 0,01567367 0,09595637 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01567367 0,09571282 ! endochondral ossification GO:0001958 16 5 0,000 0,01567367 0,09547051 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01567367 0,09522942 ! parathyroid gland development GO:0060017 13 5 0,000 0,01567367 0,09498955 ! anagen GO:0042640 6 5 0,000 0,01567367 0,09475088 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01567367 0,09451341 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01567367 0,09427713 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01567367 0,09404202 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01567367 0,09380809 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01567367 0,09357531 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01567367 0,09334369 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01567367 0,09311321 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01567367 0,09288387 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01567367 0,09265566 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01567367 0,09242856 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01567367 0,09220257 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01567367 0,09197769 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01567367 0,0917539 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01567367 0,09153119 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01567367 0,09130957 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01567367 0,09108901 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01567367 0,09086952 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01567367 0,09065109 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01567367 0,0904337 ! histidine catabolic process GO:0006548 6 5 0,000 0,01567367 0,09021735 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01567367 0,09000203 ! microvillus organization GO:0032528 7 5 0,000 0,01567367 0,08978774 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01567367 0,08957447 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01567367 0,08936221 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01567367 0,08915095 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01567367 0,08894069 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01567367 0,08873142 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01567367 0,08852313 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01567367 0,08831581 ! polyol catabolic process GO:0046174 7 5 0,000 0,01567367 0,08810947 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01567367 0,08790408 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01567367 0,08769966 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01567367 0,08749618 ! muscle cell migration GO:0014812 8 5 0,000 0,01567367 0,08729364 ! mitochondrial fission GO:0000266 8 5 0,000 0,01567367 0,08709204 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01567367 0,08689136 ! mRNA transcription GO:0009299 9 5 0,000 0,01567367 0,08669161 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01567367 0,08649278 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01567367 0,08629486 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01567367 0,08609784 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01567367 0,08590171 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01567367 0,08570648 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01567367 0,08551214 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01567367 0,08531867 ! response to food GO:0032094 6 5 0,000 0,01567367 0,08512608 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01567367 0,08493435 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01567367 0,08474349 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01567367 0,08455348 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01567367 0,08436432 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01567367 0,08417601 ! forebrain neuron development GO:0021884 13 5 0,000 0,01567367 0,08398853 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01567367 0,08380189 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01567367 0,08361608 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01567367 0,08343109 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01567367 0,08324691 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01567367 0,08306355 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01567367 0,08288099 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01567367 0,08269924 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01567367 0,08251828 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01567367 0,0823381 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01567367 0,08215872 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01567367 0,08198011 ! basic amino acid transport GO:0015802 11 5 0,000 0,01567367 0,08180228 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01567367 0,08162522 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01567367 0,08144892 ! depyrimidination GO:0045008 10 5 0,000 0,01567367 0,08127339 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01567367 0,08109861 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01567367 0,08092457 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01567367 0,08075129 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01567367 0,08057874 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01567367 0,08040693 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01567367 0,08023585 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01567367 0,0800655 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01567367 0,07989587 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01567367 0,07972696 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01567367 0,07955876 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01567367 0,07939127 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01567367 0,07922448 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01567367 0,07905839 ! response to arsenic GO:0046685 10 5 0,000 0,01567367 0,078893 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01567367 0,07872829 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01567367 0,07856427 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01567367 0,07840094 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01567367 0,07823828 ! response to cadmium ion GO:0046686 7 5 0,000 0,01567367 0,0780763 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01567367 0,07791498 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01567367 0,07775433 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01567367 0,07759435 ! decidualization GO:0046697 11 5 0,000 0,01567367 0,07743501 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01567367 0,07727634 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01567367 0,07711831 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01567367 0,07696092 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01567367 0,07680418 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01567367 0,07664807 ! neural tube patterning GO:0021532 7 5 0,000 0,01567367 0,0764926 ! embryonic cleavage GO:0040016 6 5 0,000 0,01567367 0,07633776 ! peroxisome fission GO:0016559 5 5 0,000 0,01567367 0,07618354 ! histone demethylation GO:0016577 10 5 0,000 0,01567367 0,07602994 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01567367 0,07587697 ! mitotic recombination GO:0006312 9 5 0,000 0,01567367 0,0757246 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01567367 0,07557285 ! metaphase plate congression GO:0051310 7 5 0,000 0,01567367 0,0754217 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01567367 0,07527116 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01567367 0,07512122 ! enteric nervous system development GO:0048484 8 5 0,000 0,01567367 0,07497187 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01567367 0,07482312 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01567367 0,07467495 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01567367 0,07452738 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01567367 0,07438038 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01567367 0,07423396 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01567367 0,07408812 ! plasminogen activation GO:0031639 5 5 0,000 0,01567367 0,07394285 ! B cell homeostasis GO:0001782 13 5 0,000 0,01567367 0,07379814 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01567367 0,07365401 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01567367 0,07351043 ! metaphase GO:0051323 8 5 0,000 0,01567367 0,07336742 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01567367 0,07322495 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01567367 0,07308305 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01567367 0,07294169 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01567367 0,07280087 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01567367 0,0726606 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01567367 0,07252087 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01567367 0,07238167 ! response to redox state GO:0051775 5 5 0,000 0,01567367 0,07224301 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01567367 0,07210488 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01567367 0,07196727 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01567367 0,07183019 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01567367 0,07169363 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01567367 0,07155759 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01567367 0,07142207 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01567367 0,07128705 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01567367 0,07115255 ! striatum development GO:0021756 9 5 0,000 0,01567367 0,07101855 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01567367 0,07088506 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01567367 0,07075207 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01567367 0,07061957 ! glial cell migration GO:0008347 11 5 0,000 0,01567367 0,07048757 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01567367 0,07035607 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01567367 0,07022505 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01567367 0,07009452 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01567367 0,06996447 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01567367 0,06983491 ! neuroprotection GO:0043526 6 5 0,000 0,01567367 0,06970583 ! neural plate development GO:0001840 8 5 0,000 0,01567367 0,06957722 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01567367 0,06944908 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01567367 0,06932142 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01567367 0,06919422 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01567367 0,06906749 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01567367 0,06894123 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01567367 0,06881542 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01567367 0,06869008 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01567367 0,06856519 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01567367 0,06844075 ! spindle assembly GO:0051225 6 5 0,000 0,01567367 0,06831676 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01567367 0,06819322 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01567367 0,06807013 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01567367 0,06794748 ! drug metabolic process GO:0017144 6 5 0,000 0,01567367 0,06782527 ! stem cell division GO:0017145 11 5 0,000 0,01567367 0,0677035 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01567367 0,06758217 ! organ regeneration GO:0031100 7 5 0,000 0,01567367 0,06746127 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01567367 0,06734081 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01567367 0,06722077 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01567367 0,06710116 ! ear development GO:0043583 103 62 1,000 0,01646666 0,07037083 ! gonad development GO:0008406 98 62 1,000 0,01646666 0,07024606 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01646666 0,07012173 ! germ cell development GO:0007281 118 65 1,000 0,01800242 0,07652621 ! developmental maturation GO:0021700 116 66 1,000 0,01852735 0,0786187 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01877911 0,07954673 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01877911 0,07940692 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01877911 0,07926761 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01877911 0,07912879 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01877911 0,07899045 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01877911 0,0788526 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01877911 0,07871523 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01877911 0,07857833 ! sleep GO:0030431 13 6 0,000 0,01877911 0,07844191 ! response to oxygen radical GO:0000305 11 6 0,000 0,01877911 0,07830596 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01877911 0,07817048 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01877911 0,07803547 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01877911 0,07790093 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01877911 0,07776685 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01877911 0,07763323 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01877911 0,07750007 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01877911 0,07736736 ! forebrain regionalization GO:0021871 8 6 0,000 0,01877911 0,07723511 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01877911 0,07710331 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01877911 0,07697196 ! response to zinc ion GO:0010043 9 6 0,000 0,01877911 0,07684105 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01877911 0,07671059 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01877911 0,07658058 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01877911 0,076451 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01877911 0,07632186 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01877911 0,07619315 ! malate metabolic process GO:0006108 11 6 0,000 0,01877911 0,07606488 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01877911 0,07593704 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01877911 0,07580963 ! protein refolding GO:0042026 15 6 0,000 0,01877911 0,07568265 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01877911 0,07555609 ! opsonization GO:0008228 8 6 0,000 0,01877911 0,07542995 ! mating behavior GO:0007617 7 6 0,000 0,01877911 0,07530423 ! neuron remodeling GO:0016322 15 6 0,000 0,01877911 0,07517893 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01877911 0,07505405 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01877911 0,07492959 ! equilibrioception GO:0050957 14 6 0,000 0,01877911 0,07480553 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01877911 0,07468188 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01877911 0,07455865 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01877911 0,07443582 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01877911 0,07431339 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01877911 0,07419136 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01877911 0,07406974 ! toxin metabolic process GO:0009404 11 6 0,000 0,01877911 0,07394851 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01877911 0,07382768 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01877911 0,07370724 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01877911 0,0735872 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01877911 0,07346754 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01877911 0,07334828 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01877911 0,0732294 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01877911 0,07311091 ! thymic T cell selection GO:0045061 12 6 0,000 0,01877911 0,07299279 ! protein lipoylation GO:0009249 10 6 0,000 0,01877911 0,07287506 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01877911 0,07275771 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01877911 0,07264074 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01877911 0,07252414 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01877911 0,07240792 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01877911 0,07229206 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01877911 0,07217658 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01877911 0,07206147 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01877911 0,07194672 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01877911 0,07183234 ! hyperosmotic response GO:0006972 9 6 0,000 0,01877911 0,07171832 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01877911 0,07160466 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01877911 0,07149136 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01877911 0,07137842 ! urea metabolic process GO:0019627 7 6 0,000 0,01877911 0,07126584 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01877911 0,07115361 ! neutrophil activation GO:0042119 8 6 0,000 0,01877911 0,07104173 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01877911 0,0709302 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01877911 0,07081903 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01877911 0,0707082 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01877911 0,07059772 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01877911 0,07048758 ! neuron apoptosis GO:0051402 9 6 0,000 0,01877911 0,07037779 ! nucleoside salvage GO:0043174 9 6 0,000 0,01877911 0,07026834 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01877911 0,07015922 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01877911 0,07005045 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01877911 0,06994201 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01877911 0,06983391 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01877911 0,06972614 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01877911 0,06961871 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01877911 0,0695116 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01877911 0,06940482 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01877911 0,06929837 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01877911 0,06919225 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01877911 0,06908645 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01877911 0,06898098 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01877911 0,06887582 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01877911 0,06877099 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01877911 0,06866647 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01877911 0,06856228 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01877911 0,06845839 ! neural nucleus development GO:0048857 14 6 0,000 0,01877911 0,06835483 ! astrocyte development GO:0014002 15 6 0,000 0,01877911 0,06825157 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01877911 0,06814863 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01877911 0,06804599 ! interaction with symbiont GO:0051702 13 6 0,000 0,01877911 0,06794367 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01877911 0,06784165 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01877911 0,06773994 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01877911 0,06763853 ! response to copper ion GO:0046688 10 6 0,000 0,01877911 0,06753743 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01877911 0,06743663 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01877911 0,06733612 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01877911 0,06723592 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01877911 0,06713602 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01877911 0,06703641 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01877911 0,0669371 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01877911 0,06683808 ! hair follicle maturation GO:0048820 7 6 0,000 0,01877911 0,06673935 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01877911 0,06664091 ! Schwann cell development GO:0014044 15 6 0,000 0,01877911 0,06654277 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01877911 0,06644491 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01877911 0,06634734 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01877911 0,06625006 ! subpallium development GO:0021544 10 6 0,000 0,01877911 0,06615306 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01877911 0,06605634 ! histone ubiquitination GO:0016574 8 6 0,000 0,01877911 0,06595991 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01877911 0,06586376 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01877911 0,06576789 ! G2 phase GO:0051319 16 6 0,000 0,01877911 0,0656723 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01877911 0,06557698 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01877911 0,06548194 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01877911 0,06538718 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01877911 0,06529269 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01877911 0,06519847 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01877911 0,06510452 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01877911 0,06501085 ! receptor internalization GO:0031623 10 6 0,000 0,01877911 0,06491744 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01877911 0,0648243 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01877911 0,06473143 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01877911 0,06463883 ! protein deubiquitination GO:0016579 14 6 0,000 0,01877911 0,06454649 ! protein destabilization GO:0031648 9 6 0,000 0,01877911 0,06445441 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01877911 0,06436259 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01877911 0,06427104 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01877911 0,06417974 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01877911 0,06408871 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01877911 0,06399793 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01877911 0,06390741 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01877911 0,06381715 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01877911 0,06372714 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01877911 0,06363738 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01877911 0,06354788 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01877911 0,06345862 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01877911 0,06336962 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01877911 0,06328087 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01877911 0,06319236 ! catecholamine transport GO:0051937 9 6 0,000 0,01877911 0,06310411 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01877911 0,06301609 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01877911 0,06292833 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01877911 0,06284081 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01877911 0,06275353 ! maternal placenta development GO:0001893 12 6 0,000 0,01877911 0,06266649 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01877911 0,0625797 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01877911 0,06249314 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01877911 0,06240682 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01877911 0,06232074 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01877911 0,0622349 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01877911 0,0621493 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01877911 0,06206393 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,0190587 0,06290156 ! activation of MAPK activity GO:0000187 115 67 1,000 0,0190587 0,0628154 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,0190587 0,06272946 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,0190587 0,06264377 ! adaptive immune response GO:0002250 119 67 1,000 0,0190587 0,06255831 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,01959644 0,06423573 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01959644 0,06414833 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02014051 0,06583975 ! reproductive structure development GO:0048608 113 71 1,000 0,02124748 0,06936423 ! B cell activation GO:0042113 160 71 1,000 0,02124748 0,06927024 ! regulation of caspase activity GO:0043281 122 72 1,000 0,02181029 0,07100889 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,02181029 0,07091293 ! tRNA transcription GO:0009304 14 7 0,000 0,02187486 0,07102686 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02187486 0,07093114 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02187486 0,07083567 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02187486 0,07074046 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02187486 0,07064551 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02187486 0,07055081 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02187486 0,07045636 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02187486 0,07036217 ! prostate gland development GO:0030850 13 7 0,000 0,02187486 0,07026823 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02187486 0,07017454 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02187486 0,0700811 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02187486 0,0699879 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02187486 0,06989496 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02187486 0,06980226 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02187486 0,06970981 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02187486 0,0696176 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02187486 0,06952563 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02187486 0,06943391 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02187486 0,06934243 ! glycolipid transport GO:0046836 10 7 0,000 0,02187486 0,06925119 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02187486 0,06916019 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02187486 0,06906943 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02187486 0,0689789 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02187486 0,06888862 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02187486 0,06879857 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02187486 0,06870875 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02187486 0,06861917 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02187486 0,06852982 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02187486 0,06844071 ! pericardium development GO:0060039 14 7 0,000 0,02187486 0,06835182 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02187486 0,06826317 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02187486 0,06817474 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02187486 0,06808655 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02187486 0,06799858 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02187486 0,06791084 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02187486 0,06782333 ! lipoprotein transport GO:0042953 14 7 0,000 0,02187486 0,06773604 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02187486 0,06764898 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02187486 0,06756213 ! rhythmic behavior GO:0007622 15 7 0,000 0,02187486 0,06747552 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02187486 0,06738912 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02187486 0,06730294 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02187486 0,06721699 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02187486 0,06713125 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02187486 0,06704574 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02187486 0,06696044 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02187486 0,06687535 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02187486 0,06679049 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02187486 0,06670583 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02187486 0,0666214 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02187486 0,06653717 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02187486 0,06645316 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02187486 0,06636936 ! spinal cord patterning GO:0021511 13 7 0,000 0,02187486 0,06628577 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02187486 0,06620239 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02187486 0,06611922 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02187486 0,06603626 ! adrenal gland development GO:0030325 17 7 0,000 0,02187486 0,06595351 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02187486 0,06587097 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02187486 0,06578863 ! ovulation GO:0030728 9 7 0,000 0,02187486 0,0657065 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02187486 0,06562457 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02187486 0,06554284 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02187486 0,06546132 ! microtubule nucleation GO:0007020 20 7 0,000 0,02187486 0,06538 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02187486 0,06529889 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02187486 0,06521797 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02187486 0,06513726 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02187486 0,06505674 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02187486 0,06497642 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02187486 0,0648963 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02187486 0,06481638 ! galactose metabolic process GO:0006012 13 7 0,000 0,02187486 0,06473666 ! vesicle fusion GO:0006906 17 7 0,000 0,02187486 0,06465713 ! response to dietary excess GO:0002021 8 7 0,000 0,02187486 0,06457779 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02187486 0,06449866 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02187486 0,06441971 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02187486 0,06434096 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02187486 0,0642624 ! organ growth GO:0035265 15 7 0,000 0,02187486 0,06418403 ! purine salvage GO:0043101 10 7 0,000 0,02187486 0,06410585 ! nucleoside transport GO:0015858 8 7 0,000 0,02187486 0,06402786 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02187486 0,06395006 ! parturition GO:0007567 14 7 0,000 0,02187486 0,06387245 ! rRNA modification GO:0000154 14 7 0,000 0,02187486 0,06379503 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02187486 0,0637178 ! spindle checkpoint GO:0031577 15 7 0,000 0,02187486 0,06364075 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02187486 0,06356389 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02187486 0,06348722 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02187486 0,06341073 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02187486 0,06333442 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02187486 0,0632583 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02187486 0,06318236 ! fibrinolysis GO:0042730 10 7 0,000 0,02187486 0,0631066 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02187486 0,06303102 ! eating behavior GO:0042755 7 7 0,000 0,02187486 0,06295563 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02187486 0,06288041 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02187486 0,06280537 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02187486 0,06273052 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02187486 0,06265584 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02187486 0,06258134 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02187486 0,06250701 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02187486 0,06243286 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02187486 0,06235889 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02187486 0,06228509 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02187486 0,06221147 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02187486 0,06213802 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02187486 0,06206474 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02187486 0,06199164 ! regulation of meiosis GO:0040020 12 7 0,000 0,02187486 0,06191871 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02187486 0,06184595 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02187486 0,06177336 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02187486 0,06170094 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02187486 0,06162869 ! transcription termination GO:0006353 13 7 0,000 0,02187486 0,06155661 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02187486 0,0614847 ! anaphase GO:0051322 17 7 0,000 0,02187486 0,06141296 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02187486 0,06134138 ! axonal fasciculation GO:0007413 18 7 0,000 0,02187486 0,06126997 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02187486 0,06119872 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02187486 0,06112765 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02187486 0,06105673 ! diuresis GO:0030146 12 7 0,000 0,02187486 0,06098598 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02187486 0,0609154 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02187486 0,06084497 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02187486 0,06077471 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02187486 0,06070462 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02187486 0,06063468 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02187486 0,06056491 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02187486 0,06049529 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02187486 0,06042584 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02187486 0,06035654 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02187486 0,0602874 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02187486 0,06021842 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02187486 0,0601496 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02187486 0,06008094 ! lymph node development GO:0048535 10 7 0,000 0,02187486 0,06001243 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02187486 0,05994408 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02187486 0,05987588 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02187486 0,05980784 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02187486 0,05973996 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02187486 0,05967223 ! adult feeding behavior GO:0008343 9 7 0,000 0,02187486 0,05960465 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02187486 0,05953722 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02187486 0,05946995 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02187486 0,05940282 ! muscle adaptation GO:0043500 14 7 0,000 0,02187486 0,05933585 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02187486 0,05926903 ! retina homeostasis GO:0001895 12 7 0,000 0,02187486 0,05920237 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02187486 0,05913585 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02187486 0,05906948 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02187486 0,05900325 ! protein prenylation GO:0018342 18 7 0,000 0,02187486 0,05893718 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02187486 0,05887126 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02187486 0,05880548 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02187486 0,05873985 ! axon guidance GO:0007411 139 73 1,000 0,02237927 0,06002734 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02295436 0,06150133 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,02353553 0,06298829 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02353553 0,06291831 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,02412272 0,0644165 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,0247159 0,06592734 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02496094 0,06650721 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02496094 0,06643364 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02496094 0,06636024 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02496094 0,06628699 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02496094 0,06621391 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02496094 0,06614098 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02496094 0,06606822 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02496094 0,06599562 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02496094 0,06592318 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02496094 0,06585089 ! meiotic prophase I GO:0007128 13 8 0,000 0,02496094 0,06577877 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02496094 0,0657068 ! oligopeptide transport GO:0006857 15 8 0,000 0,02496094 0,06563499 ! UTP metabolic process GO:0046051 8 8 0,000 0,02496094 0,06556333 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02496094 0,06549184 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02496094 0,06542049 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02496094 0,06534931 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02496094 0,06527827 ! succinate metabolic process GO:0006105 14 8 0,000 0,02496094 0,0652074 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02496094 0,06513667 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02496094 0,0650661 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02496094 0,06499568 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02496094 0,06492542 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02496094 0,06485531 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02496094 0,06478534 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02496094 0,06471553 ! reflex GO:0060004 16 8 0,000 0,02496094 0,06464587 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02496094 0,06457636 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02496094 0,064507 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02496094 0,06443778 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02496094 0,06436872 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02496094 0,0642998 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02496094 0,06423103 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02496094 0,06416241 ! pigment granule organization GO:0048753 16 8 0,000 0,02496094 0,06409393 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02496094 0,0640256 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02496094 0,06395742 ! histidine metabolic process GO:0006547 16 8 0,000 0,02496094 0,06388938 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02496094 0,06382148 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02496094 0,06375373 ! glycine catabolic process GO:0006546 13 8 0,000 0,02496094 0,06368612 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02496094 0,06361866 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02496094 0,06355134 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02496094 0,06348416 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02496094 0,06341712 ! melanin metabolic process GO:0006582 15 8 0,000 0,02496094 0,06335022 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02496094 0,06328347 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02496094 0,06321686 ! macrophage activation GO:0042116 12 8 0,000 0,02496094 0,06315038 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02496094 0,06308405 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02496094 0,06301785 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02496094 0,0629518 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02496094 0,06288588 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02496094 0,0628201 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02496094 0,06275445 ! osteoblast development GO:0002076 16 8 0,000 0,02496094 0,06268895 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02496094 0,06262358 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02496094 0,06255835 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02496094 0,06249325 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02496094 0,06242829 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02496094 0,06236346 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02496094 0,06229877 ! response to UV-B GO:0010224 16 8 0,000 0,02496094 0,06223421 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02496094 0,06216979 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02496094 0,06210549 ! intermediate filament organization GO:0045109 12 8 0,000 0,02496094 0,06204134 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02496094 0,06197731 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02496094 0,06191342 ! cellular extravasation GO:0045123 12 8 0,000 0,02496094 0,06184965 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02496094 0,06178602 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02496094 0,06172252 ! response to antibiotic GO:0046677 11 8 0,000 0,02496094 0,06165915 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02496094 0,06159591 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02496094 0,0615328 ! DNA topological change GO:0006265 12 8 0,000 0,02496094 0,06146982 ! response to tropane GO:0014073 15 8 0,000 0,02496094 0,06140697 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02496094 0,06134424 ! melanosome transport GO:0032402 13 8 0,000 0,02496094 0,06128165 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02496094 0,06121918 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02496094 0,06115684 ! mast cell activation GO:0045576 14 8 0,000 0,02496094 0,06109462 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02496094 0,06103253 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02496094 0,06097057 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02496094 0,06090874 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02496094 0,06084702 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02496094 0,06078544 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02496094 0,06072398 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02496094 0,06066264 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02496094 0,06060143 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02496094 0,06054034 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02496094 0,06047937 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02496094 0,06041852 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02496094 0,0603578 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02496094 0,0602972 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02496094 0,06023672 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02496094 0,06017637 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02496094 0,06011613 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02496094 0,06005601 ! hormone catabolic process GO:0042447 17 8 0,000 0,02496094 0,05999602 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02496094 0,05993614 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02496094 0,05987638 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02496094 0,05981675 ! ATP catabolic process GO:0006200 11 8 0,000 0,02496094 0,05975723 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02496094 0,05969783 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02496094 0,05963854 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02496094 0,05957938 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02496094 0,05952033 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02496094 0,0594614 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02496094 0,05940258 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02496094 0,05934389 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02496094 0,0592853 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02496094 0,05922684 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02496094 0,05916849 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02496094 0,05911025 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02496094 0,05905213 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02496094 0,05899412 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02496094 0,05893622 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02496094 0,05887844 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02496094 0,05882078 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,02531503 0,05959683 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02592006 0,06096155 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02592006 0,06090202 ! protein import into nucleus GO:0006606 158 80 1,000 0,02653095 0,06227655 ! T cell activation GO:0042110 168 81 1,000 0,02714765 0,06366204 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,02714765 0,06360005 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,02714765 0,06353819 ! nuclear import GO:0051170 161 81 1,000 0,02714765 0,06347644 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,02714765 0,06341481 ! response to drug GO:0042493 143 82 1,000 0,02777014 0,06480596 ! axon extension GO:0048675 15 9 0,000 0,02803738 0,06536622 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02803738 0,06530294 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02803738 0,06523979 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02803738 0,06517676 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02803738 0,06511384 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02803738 0,06505105 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02803738 0,06498838 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02803738 0,06492583 ! phosphate transport GO:0006817 19 9 0,000 0,02803738 0,06486341 ! reproductive behavior GO:0019098 19 9 0,000 0,02803738 0,0648011 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02803738 0,06473891 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02803738 0,06467684 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02803738 0,06461489 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02803738 0,06455305 ! GTP metabolic process GO:0046039 9 9 0,000 0,02803738 0,06449134 ! RNA methylation GO:0001510 15 9 0,000 0,02803738 0,06442974 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02803738 0,06436827 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02803738 0,0643069 ! artery development GO:0060840 24 9 0,000 0,02803738 0,06424566 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02803738 0,06418453 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02803738 0,06412352 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02803738 0,06406262 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02803738 0,06400184 ! chemosensory behavior GO:0007635 20 9 0,000 0,02803738 0,06394118 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02803738 0,06388063 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02803738 0,06382019 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02803738 0,06375987 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02803738 0,06369966 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02803738 0,06363957 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02803738 0,06357959 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02803738 0,06351972 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02803738 0,06345996 ! protein targeting to ER GO:0045047 22 9 0,000 0,02803738 0,06340032 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02803738 0,06334079 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02803738 0,06328137 ! T cell selection GO:0045058 23 9 0,000 0,02803738 0,06322206 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02803738 0,06316287 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02803738 0,06310378 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02803738 0,06304481 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02803738 0,06298594 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02803738 0,06292718 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02803738 0,06286854 ! mannose metabolic process GO:0006013 13 9 0,000 0,02803738 0,06281 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02803738 0,06275157 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02803738 0,06269325 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02803738 0,06263504 ! receptor clustering GO:0043113 18 9 0,000 0,02803738 0,06257694 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02803738 0,06251895 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02803738 0,06246106 ! ruffle organization GO:0031529 15 9 0,000 0,02803738 0,06240328 ! retinol metabolic process GO:0042572 18 9 0,000 0,02803738 0,0623456 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02803738 0,06228803 ! behavioral fear response GO:0001662 22 9 0,000 0,02803738 0,06223057 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02803738 0,06217322 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02803738 0,06211597 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02803738 0,06205882 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02803738 0,06200178 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02803738 0,06194485 ! segment specification GO:0007379 13 9 0,000 0,02803738 0,06188802 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02803738 0,06183129 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02803738 0,06177467 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02803738 0,06171815 ! response to amine stimulus GO:0014075 13 9 0,000 0,02803738 0,06166174 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02803738 0,06160543 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02803738 0,06154922 ! erythrocyte development GO:0048821 15 9 0,000 0,02803738 0,06149311 ! gas homeostasis GO:0033483 16 9 0,000 0,02803738 0,06143711 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02803738 0,0613812 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02803738 0,0613254 ! renal water homeostasis GO:0003091 14 9 0,000 0,02803738 0,0612697 ! postreplication repair GO:0006301 22 9 0,000 0,02803738 0,0612141 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02803738 0,06115861 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02803738 0,06110321 ! icosanoid secretion GO:0032309 15 9 0,000 0,02803738 0,06104791 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02803738 0,06099271 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02803738 0,06093762 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02803738 0,06088262 ! regulation of cell division GO:0051302 15 9 0,000 0,02803738 0,06082772 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02803738 0,06077292 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02803738 0,06071822 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02803738 0,06066362 ! sterol catabolic process GO:0016127 11 9 0,000 0,02803738 0,06060911 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02803738 0,06055471 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02803738 0,0605004 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02803738 0,06044618 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02803738 0,06039207 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02803738 0,06033805 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02803738 0,06028413 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02803738 0,06023031 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02803738 0,06017658 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02803738 0,06012294 ! purine base metabolic process GO:0006144 21 9 0,000 0,02803738 0,06006941 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02803738 0,06001596 ! pigment granule transport GO:0051904 17 9 0,000 0,02803738 0,05996261 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02803738 0,05990936 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02803738 0,0598562 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02803738 0,05980314 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02803738 0,05975017 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02803738 0,05969729 ! mitochondrion localization GO:0051646 15 9 0,000 0,02803738 0,05964451 ! response to oxygen levels GO:0070482 176 83 1,000 0,02839835 0,06035904 ! negative regulation of transport GO:0051051 153 84 1,000 0,02903226 0,06165191 ! nucleosome assembly GO:0006334 122 85 1,000 0,02967182 0,06295449 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02967182 0,06289902 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 124 86 1,000 0,03031698 0,06421009 ! tube morphogenesis GO:0035239 176 86 1,000 0,03031698 0,06415362 ! mitochondrion organization GO:0007005 148 86 1,000 0,03031698 0,06409724 ! protein localization in nucleus GO:0034504 176 87 1,000 0,03096772 0,06541557 ! regulation of protein transport GO:0051223 154 87 1,000 0,03096772 0,06535819 GO:0070201|regulation of establishment of protein localization, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03110422 0,06558875 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03110422 0,06553131 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03110422 0,06547398 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03110422 0,06541675 ! synapsis GO:0007129 13 10 0,000 0,03110422 0,06535962 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03110422 0,06530258 ! N-glycan processing GO:0006491 20 10 0,000 0,03110422 0,06524565 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03110422 0,06518882 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03110422 0,06513208 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03110422 0,06507544 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03110422 0,06501891 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03110422 0,06496247 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03110422 0,06490612 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03110422 0,06484988 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03110422 0,06479373 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03110422 0,06473768 ! androgen metabolic process GO:0008209 17 10 0,000 0,03110422 0,06468173 ! phospholipid efflux GO:0033700 16 10 0,000 0,03110422 0,06462587 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03110422 0,06457011 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03110422 0,06451445 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03110422 0,06445888 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03110422 0,06440341 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03110422 0,06434803 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03110422 0,06429275 ! endoderm development GO:0007492 16 10 0,000 0,03110422 0,06423756 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03110422 0,06418247 ! arginine catabolic process GO:0006527 13 10 0,000 0,03110422 0,06412747 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03110422 0,06407257 ! proline metabolic process GO:0006560 13 10 0,000 0,03110422 0,06401776 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03110422 0,06396304 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03110422 0,06390842 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03110422 0,06385389 ! V(D)J recombination GO:0033151 28 10 0,000 0,03110422 0,06379946 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03110422 0,06374511 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03110422 0,06369086 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03110422 0,0636367 ! B cell proliferation GO:0042100 18 10 0,000 0,03110422 0,06358263 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03110422 0,06352866 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03110422 0,06347478 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03110422 0,06342098 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03110422 0,06336728 ! epithelial cell development GO:0002064 20 10 0,000 0,03110422 0,06331367 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03110422 0,06326015 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03110422 0,06320672 ! macroautophagy GO:0016236 17 10 0,000 0,03110422 0,06315339 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03110422 0,06310014 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03110422 0,06304698 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03110422 0,06299391 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03110422 0,06294093 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03110422 0,06288803 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03110422 0,06283523 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03110422 0,06278252 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03110422 0,06272989 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03110422 0,06267735 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03110422 0,0626249 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03110422 0,06257254 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03110422 0,06252027 ! response to dsRNA GO:0043331 20 10 0,000 0,03110422 0,06246808 ! DNA ligation GO:0006266 19 10 0,000 0,03110422 0,06241598 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03110422 0,06236397 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03110422 0,06231204 ! melanosome localization GO:0032400 16 10 0,000 0,03110422 0,0622602 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03110422 0,06220845 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03110422 0,06215678 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03110422 0,0621052 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03110422 0,0620537 ! mRNA cleavage GO:0006379 17 10 0,000 0,03110422 0,06200229 ! protein sumoylation GO:0016925 15 10 0,000 0,03110422 0,06195096 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03110422 0,06189972 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03110422 0,06184856 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03110422 0,06179749 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03110422 0,0617465 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03110422 0,0616956 ! salivary gland development GO:0007431 27 10 0,000 0,03110422 0,06164478 ! prophase GO:0051324 15 10 0,000 0,03110422 0,06159404 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03110422 0,06154339 ! apical protein localization GO:0045176 15 10 0,000 0,03110422 0,06149282 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03110422 0,06144233 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03110422 0,06139193 ! midbrain development GO:0030901 13 10 0,000 0,03110422 0,06134161 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03110422 0,06129137 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03110422 0,06124121 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03110422 0,06119114 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03110422 0,06114114 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03110422 0,06109123 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03110422 0,0610414 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03110422 0,06099166 ! detection of calcium ion GO:0005513 23 10 0,000 0,03110422 0,06094199 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03110422 0,0608924 ! blastocyst formation GO:0001825 17 10 0,000 0,03110422 0,0608429 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03110422 0,06079347 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03110422 0,06074412 ! activation of innate immune response GO:0002218 12 10 0,000 0,03110422 0,06069486 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03110422 0,06064567 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03110422 0,06059657 ! response to nicotine GO:0035094 20 10 0,000 0,03110422 0,06054754 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03110422 0,06049859 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03110422 0,06044973 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,03228574 0,0626953 ! ossification GO:0001503 188 90 1,000 0,03295294 0,06393932 ! sex differentiation GO:0007548 145 90 1,000 0,03295294 0,0638878 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,03295294 0,06383636 ! bone development GO:0060348 189 91 1,000 0,03362554 0,06508693 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03416149 0,06607118 ! respiratory burst GO:0045730 17 11 0,000 0,03416149 0,06601811 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03416149 0,06596512 ! neuron fate specification GO:0048665 17 11 0,000 0,03416149 0,06591222 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03416149 0,06585941 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03416149 0,06580668 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03416149 0,06575403 ! thyroid gland development GO:0030878 26 11 0,000 0,03416149 0,06570147 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03416149 0,065649 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03416149 0,0655966 ! response to pain GO:0048265 24 11 0,000 0,03416149 0,06554429 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03416149 0,06549207 ! T cell proliferation GO:0042098 26 11 0,000 0,03416149 0,06543992 ! bone resorption GO:0045453 16 11 0,000 0,03416149 0,06538786 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,03416149 0,06533588 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03416149 0,06528399 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03416149 0,06523218 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03416149 0,06518045 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03416149 0,0651288 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03416149 0,06507723 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03416149 0,06502575 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03416149 0,06497434 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03416149 0,06492302 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03416149 0,06487178 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03416149 0,06482062 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03416149 0,06476954 ! UV protection GO:0009650 19 11 0,000 0,03416149 0,06471854 ! adult heart development GO:0007512 14 11 0,000 0,03416149 0,06466762 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03416149 0,06461678 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03416149 0,06456602 ! temperature homeostasis GO:0001659 17 11 0,000 0,03416149 0,06451534 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03416149 0,06446474 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03416149 0,06441422 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03416149 0,06436378 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03416149 0,06431341 ! regulation of organ growth GO:0046620 13 11 0,000 0,03416149 0,06426313 ! pigment granule localization GO:0051875 20 11 0,000 0,03416149 0,06421292 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03416149 0,0641628 ! vasoconstriction GO:0042310 18 11 0,000 0,03416149 0,06411275 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03416149 0,06406278 ! embryonic axis specification GO:0000578 18 11 0,000 0,03416149 0,06401288 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03416149 0,06396307 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03416149 0,06391333 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03416149 0,06386367 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03416149 0,06381409 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03416149 0,06376458 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03416149 0,06371515 ! zymogen activation GO:0031638 15 11 0,000 0,03416149 0,0636658 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03416149 0,06361652 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03416149 0,06356732 ! nucleosome positioning GO:0016584 15 11 0,000 0,03416149 0,06351819 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03416149 0,06346914 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03416149 0,06342017 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03416149 0,06337127 ! acid secretion GO:0046717 18 11 0,000 0,03416149 0,06332245 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03416149 0,0632737 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03416149 0,06322503 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03416149 0,06317644 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03416149 0,06312791 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03416149 0,06307946 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03416149 0,06303109 ! cholesterol efflux GO:0033344 19 11 0,000 0,03416149 0,06298279 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03416149 0,06293457 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03416149 0,06288641 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03416149 0,06283834 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03416149 0,06279033 ! embryonic gut development GO:0048566 15 11 0,000 0,03416149 0,0627424 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03416149 0,06269454 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03416149 0,06264676 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03416149 0,06259904 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03416149 0,0625514 ! defense response to fungus GO:0050832 13 11 0,000 0,03416149 0,06250383 ! developmental induction GO:0031128 19 11 0,000 0,03416149 0,06245634 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03416149 0,06240892 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03416149 0,06236156 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03416149 0,06231429 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03416149 0,06226708 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03416149 0,06221994 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03416149 0,06217288 ! nucleosome organization GO:0034728 138 92 1,000 0,03430351 0,06238417 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03498681 0,06357876 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03498681 0,06353077 ! female pregnancy GO:0007565 164 94 1,000 0,0356754 0,06473229 ! regulation of T cell activation GO:0050863 158 94 1,000 0,0356754 0,06468351 ! forebrain development GO:0030900 188 95 1,000 0,03636924 0,06589186 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03720921 0,06736295 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03720921 0,0673123 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03720921 0,06726173 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03720921 0,06721123 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03720921 0,06716081 ! cartilage condensation GO:0001502 20 12 0,000 0,03720921 0,06711046 ! mating GO:0007618 17 12 0,000 0,03720921 0,06706019 ! protein complex disassembly GO:0043241 27 12 0,000 0,03720921 0,06701 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03720921 0,06695988 ! hippocampus development GO:0021766 26 12 0,000 0,03720921 0,06690983 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03720921 0,06685986 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03720921 0,06680997 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03720921 0,06676015 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03720921 0,0667104 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03720921 0,06666073 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03720921 0,06661113 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03720921 0,0665616 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03720921 0,06651215 ! drug transport GO:0015893 16 12 0,000 0,03720921 0,06646277 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03720921 0,06641347 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03720921 0,06636424 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03720921 0,06631508 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03720921 0,06626599 ! focal adhesion formation GO:0048041 35 12 0,000 0,03720921 0,06621698 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03720921 0,06616804 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03720921 0,06611917 ! forebrain cell migration GO:0021885 21 12 0,000 0,03720921 0,06607037 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03720921 0,06602165 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03720921 0,065973 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03720921 0,06592442 ! fear response GO:0042596 26 12 0,000 0,03720921 0,06587591 ! monoamine transport GO:0015844 18 12 0,000 0,03720921 0,06582747 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03720921 0,0657791 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03720921 0,06573081 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03720921 0,06568258 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03720921 0,06563443 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03720921 0,06558634 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03720921 0,06553833 ! protein homotetramerization GO:0051289 21 12 0,000 0,03720921 0,06549039 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03720921 0,06544251 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03720921 0,06539471 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03720921 0,06534698 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03720921 0,06529931 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03720921 0,06525172 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03720921 0,06520419 ! cranial nerve development GO:0021545 20 12 0,000 0,03720921 0,06515674 ! fucose catabolic process GO:0019317 22 12 0,000 0,03720921 0,06510935 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03720921 0,06506203 ! histone acetylation GO:0016573 26 12 0,000 0,03720921 0,06501478 ! histone methylation GO:0016571 26 12 0,000 0,03720921 0,0649676 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03720921 0,06492049 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03720921 0,06487345 ! gland morphogenesis GO:0022612 29 12 0,000 0,03720921 0,06482647 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03720921 0,06477956 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03720921 0,06473272 ! T cell homeostasis GO:0043029 25 12 0,000 0,03720921 0,06468595 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03720921 0,06463925 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03720921 0,06459261 ! spleen development GO:0048536 22 12 0,000 0,03720921 0,06454604 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03720921 0,06449954 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03720921 0,0644531 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03720921 0,06440673 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03720921 0,06436043 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03720921 0,06431419 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03720921 0,06426802 ! response to cold GO:0009409 17 12 0,000 0,03720921 0,06422192 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03720921 0,06417588 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03720921 0,06412991 ! protein ubiquitination GO:0016567 217 97 1,000 0,0377725 0,06505414 ! regulation of protein localization GO:0032880 176 97 1,000 0,0377725 0,0650076 ! response to virus GO:0009615 160 98 1,000 0,03848184 0,06618107 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03919628 0,06736161 GO:0060538|skeletal muscle organ development, ! cGMP metabolic process GO:0046068 18 13 0,000 0,04024741 0,06911868 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04024741 0,06906938 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04024741 0,06902015 ! peroxisomal transport GO:0043574 24 13 0,000 0,04024741 0,06897099 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04024741 0,0689219 ! lipid localization GO:0010876 28 13 0,000 0,04024741 0,06887288 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04024741 0,06882393 ! organelle fusion GO:0048284 32 13 0,000 0,04024741 0,06877505 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04024741 0,06872624 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04024741 0,0686775 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04024741 0,06862883 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04024741 0,06858022 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04024741 0,06853169 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04024741 0,06848322 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04024741 0,06843482 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04024741 0,06838649 ! methionine metabolic process GO:0006555 27 13 0,000 0,04024741 0,06833823 ! plasma membrane organization GO:0007009 24 13 0,000 0,04024741 0,06829004 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04024741 0,06824191 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04024741 0,06819386 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04024741 0,06814587 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04024741 0,06809794 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04024741 0,06805009 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04024741 0,0680023 ! exocrine system development GO:0035272 32 13 0,000 0,04024741 0,06795458 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04024741 0,06790693 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04024741 0,06785934 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04024741 0,06781182 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04024741 0,06776436 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04024741 0,06771698 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04024741 0,06766965 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04024741 0,0676224 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04024741 0,06757521 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04024741 0,06752809 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04024741 0,06748103 ! ribosome assembly GO:0042255 17 13 0,000 0,04024741 0,06743404 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04024741 0,06738711 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04024741 0,06734025 ! chromatin silencing GO:0006342 26 13 0,000 0,04024741 0,06729345 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04024741 0,06724672 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04024741 0,06720005 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04024741 0,06715345 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04024741 0,06710691 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04024741 0,06706044 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04024741 0,06701403 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04024741 0,06696769 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04024741 0,06692141 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04024741 0,06687519 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04024741 0,06682904 ! embryonic placenta development GO:0001892 23 13 0,000 0,04024741 0,06678295 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04024741 0,06673692 ! insulin secretion GO:0030073 23 13 0,000 0,04024741 0,06669096 ! actin filament polymerization GO:0030041 24 13 0,000 0,04024741 0,06664506 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04024741 0,06659923 ! acrosome reaction GO:0007340 18 13 0,000 0,04024741 0,06655345 ! rRNA transcription GO:0009303 25 14 0,000 0,04327613 0,07151262 ! lactation GO:0007595 26 14 0,000 0,04327613 0,07146353 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,04327613 0,07141452 ! reproductive cellular process GO:0048610 20 14 0,000 0,04327613 0,07136557 ! tRNA modification GO:0006400 20 14 0,000 0,04327613 0,07131669 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04327613 0,07126788 ! water transport GO:0006833 21 14 0,000 0,04327613 0,07121913 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04327613 0,07117045 ! non-recombinational repair GO:0000726 25 14 0,000 0,04327613 0,07112184 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04327613 0,07107329 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04327613 0,07102481 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04327613 0,07097639 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04327613 0,07092804 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04327613 0,07087976 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04327613 0,07083154 ! palate development GO:0060021 31 14 0,000 0,04327613 0,07078339 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04327613 0,0707353 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04327613 0,07068728 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04327613 0,07063933 ! arginine metabolic process GO:0006525 17 14 0,000 0,04327613 0,07059144 ! regulation of heart rate GO:0002027 24 14 0,000 0,04327613 0,07054361 ! organic alcohol transport GO:0015850 29 14 0,000 0,04327613 0,07049585 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04327613 0,07044815 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04327613 0,07040052 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04327613 0,07035295 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04327613 0,07030545 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04327613 0,07025801 ! L-amino acid transport GO:0015807 30 14 0,000 0,04327613 0,07021063 ! bone mineralization GO:0030282 17 14 0,000 0,04327613 0,07016332 ! stem cell development GO:0048864 43 14 0,000 0,04327613 0,07011607 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04327613 0,07006889 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04327613 0,07002177 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04327613 0,06997471 ! cerebellum development GO:0021549 21 14 0,000 0,04327613 0,06992772 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04327613 0,06988078 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04327613 0,06983392 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04327613 0,06978711 ! cofactor transport GO:0051181 26 14 0,000 0,04327613 0,06974037 ! NADP metabolic process GO:0006739 24 14 0,000 0,04327613 0,06969369 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04327613 0,06964707 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04327613 0,06960051 ! intestinal absorption GO:0050892 25 14 0,000 0,04327613 0,06955402 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04327613 0,06950759 ! oxygen transport GO:0015671 21 14 0,000 0,04327613 0,06946122 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04327613 0,06941491 ! male genitalia development GO:0030539 24 14 0,000 0,04327613 0,06936867 ! regulation of axon extension GO:0030516 37 14 0,000 0,04327613 0,06932248 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04327613 0,06927636 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04629539 0,07406031 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04629539 0,0740111 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04629539 0,07396196 ! superoxide anion generation GO:0042554 20 15 0,000 0,04629539 0,07391288 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04629539 0,07386386 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04629539 0,07381491 ! copper ion transport GO:0006825 20 15 0,000 0,04629539 0,07376603 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04629539 0,07371721 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04629539 0,07366846 ! sulfate transport GO:0008272 23 15 0,000 0,04629539 0,07361977 ! response to cAMP GO:0051591 22 15 0,000 0,04629539 0,07357114 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04629539 0,07352258 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04629539 0,07347408 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04629539 0,07342565 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04629539 0,07337728 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04629539 0,07332897 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04629539 0,07328073 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04629539 0,07323255 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04629539 0,07318443 ! pituitary gland development GO:0021983 29 15 0,000 0,04629539 0,07313638 ! vesicle coating GO:0006901 33 15 0,000 0,04629539 0,07308839 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04629539 0,07304046 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04629539 0,0729926 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04629539 0,0729448 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04629539 0,07289706 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04629539 0,07284938 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04629539 0,07280177 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04629539 0,07275422 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04629539 0,07270673 ! histone deacetylation GO:0016575 20 15 0,000 0,04629539 0,0726593 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04629539 0,07261193 ! tissue regeneration GO:0042246 26 15 0,000 0,04629539 0,07256463 ! water homeostasis GO:0030104 27 15 0,000 0,04629539 0,07251739 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04629539 0,07247021 ! muscle maintenance GO:0046716 26 15 0,000 0,04629539 0,07242309 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04629539 0,07237603 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04629539 0,07232903 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04629539 0,07228209 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04629539 0,07223522 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04629539 0,0721884 ! cell killing GO:0001906 29 15 0,000 0,04629539 0,07214165 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04629539 0,07209496 ! detection of bacterium GO:0016045 18 15 0,000 0,04629539 0,07204832 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04629539 0,07200175 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04629539 0,07195524 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04629539 0,07190878 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04629539 0,07186239 ! peptide hormone processing GO:0016486 23 15 0,000 0,04629539 0,07181606 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04930522 0,0764358 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04930522 0,07638658 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04930522 0,07633743 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04930522 0,07628833 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04930522 0,07623931 ! bone remodeling GO:0046849 27 16 0,000 0,04930522 0,07619034 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04930522 0,07614144 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04930522 0,0760926 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04930522 0,07604382 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04930522 0,07599511 ! startle response GO:0001964 28 16 0,000 0,04930522 0,07594645 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04930522 0,07589786 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04930522 0,07584934 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04930522 0,07580087 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04930522 0,07575247 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04930522 0,07570412 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04930522 0,07565584 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04930522 0,07560762 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04930522 0,07555947 ! response to osmotic stress GO:0006970 25 16 0,000 0,04930522 0,07551137 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04930522 0,07546333 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04930522 0,07541536 ! fructose metabolic process GO:0006000 25 16 0,000 0,04930522 0,07536745 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04930522 0,07531959 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04930522 0,0752718 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04930522 0,07522407 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04930522 0,0751764 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04930522 0,07512879 ! axon cargo transport GO:0008088 43 16 0,000 0,04930522 0,07508124 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04930522 0,07503375 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04930522 0,07498632 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04930522 0,07493895 ! DNA replication initiation GO:0006270 27 16 0,000 0,04930522 0,07489164 ! neuron recognition GO:0008038 35 16 0,000 0,04930522 0,07484439 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04930522 0,0747972 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04930522 0,07475007 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04930522 0,074703 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04930522 0,07465599 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04930522 0,07460903 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04930522 0,07456214 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04930522 0,0745153 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04930522 0,07446853 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04930522 0,07442181 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04930522 0,07437515 ! defense response to virus GO:0051607 37 16 0,000 0,04930522 0,07432855 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05230565 0,07880238 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05230565 0,07875307 ! metencephalon development GO:0022037 30 17 0,000 0,05230565 0,07870381 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05230565 0,07865462 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05230565 0,0786055 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05230565 0,07855643 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05230565 0,07850742 ! signal complex assembly GO:0007172 41 17 0,000 0,05230565 0,07845848 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05230565 0,07840959 ! glial cell development GO:0021782 27 17 0,000 0,05230565 0,07836077 ! limbic system development GO:0021761 36 17 0,000 0,05230565 0,07831201 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05230565 0,07826331 ! adult walking behavior GO:0007628 33 17 0,000 0,05230565 0,07821467 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05230565 0,07816609 ! heart looping GO:0001947 30 17 0,000 0,05230565 0,07811757 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05230565 0,07806911 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05230565 0,07802071 ! myoblast differentiation GO:0045445 45 17 0,000 0,05230565 0,07797237 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05230565 0,07792409 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05230565 0,07787587 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05230565 0,07782771 ! glycine metabolic process GO:0006544 28 17 0,000 0,05230565 0,0777796 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05230565 0,07773156 ! NAD metabolic process GO:0019674 29 17 0,000 0,05230565 0,07768358 ! membrane budding GO:0006900 37 17 0,000 0,05230565 0,07763566 ! DNA integration GO:0015074 29 17 0,000 0,05230565 0,07758779 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05230565 0,07753999 ! regulation of protein binding GO:0043393 33 17 0,000 0,05230565 0,07749224 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05230565 0,07744455 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05230565 0,07739692 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05230565 0,07734935 ! genitalia development GO:0048806 30 17 0,000 0,05230565 0,07730184 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05230565 0,07725439 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05230565 0,07720699 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05230565 0,07715966 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05230565 0,07711238 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05230565 0,07706516 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05230565 0,07701799 ! steroid catabolic process GO:0006706 31 17 0,000 0,05230565 0,07697089 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05230565 0,07692384 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05230565 0,07687685 ! gas transport GO:0015669 25 17 0,000 0,05230565 0,07682991 ! organic cation transport GO:0015695 31 17 0,000 0,05230565 0,07678304 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05230565 0,07673622 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05230565 0,07668946 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05230565 0,07664275 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05230565 0,0765961 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05529671 0,08092694 ! neuron maturation GO:0042551 42 18 0,000 0,05529671 0,08087775 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05529671 0,08082861 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05529671 0,08077954 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05529671 0,08073052 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05529671 0,08068156 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05529671 0,08063266 ! memory GO:0007613 31 18 0,000 0,05529671 0,08058382 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05529671 0,08053505 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05529671 0,08048632 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05529671 0,08043766 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05529671 0,08038906 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05529671 0,08034052 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05529671 0,08029203 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05529671 0,0802436 ! response to retinoic acid GO:0032526 26 18 0,000 0,05529671 0,08019523 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05529671 0,08014692 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05529671 0,08009867 ! response to fungus GO:0009620 21 18 0,000 0,05529671 0,08005048 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05529671 0,08000234 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05529671 0,07995426 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05529671 0,07990624 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05529671 0,07985828 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05529671 0,07981037 ! vitamin transport GO:0051180 27 18 0,000 0,05529671 0,07976253 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05529671 0,07971474 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05529671 0,079667 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05529671 0,07961933 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05529671 0,07957171 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05529671 0,07952415 ! nerve development GO:0021675 28 18 0,000 0,05529671 0,07947664 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05529671 0,07942919 ! protein secretion GO:0009306 39 19 0,000 0,05827844 0,08366224 ! positive regulation of translation GO:0045727 30 19 0,000 0,05827844 0,08361235 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05827844 0,08356252 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05827844 0,08351275 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05827844 0,08346304 ! skin development GO:0043588 36 19 0,000 0,05827844 0,08341339 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05827844 0,0833638 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05827844 0,08331427 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05827844 0,08326479 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05827844 0,08321538 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05827844 0,08316602 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05827844 0,08311672 ! cerebral cortex development GO:0021987 36 19 0,000 0,05827844 0,08306749 ! pigmentation during development GO:0048066 41 19 0,000 0,05827844 0,0830183 ! response to vitamin A GO:0033189 27 19 0,000 0,05827844 0,08296918 ! heme metabolic process GO:0042168 36 19 0,000 0,05827844 0,08292012 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05827844 0,08287111 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05827844 0,08282216 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05827844 0,08277327 ! peptide cross-linking GO:0018149 37 19 0,000 0,05827844 0,08272443 ! protein export from nucleus GO:0006611 36 19 0,000 0,05827844 0,08267566 ! heart process GO:0003015 30 19 0,000 0,05827844 0,08262694 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05827844 0,08257828 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05827844 0,08252967 ! visual learning GO:0008542 36 19 0,000 0,05827844 0,08248113 ! cellular pigmentation GO:0033059 36 19 0,000 0,05827844 0,08243264 ! G1 phase GO:0051318 40 19 0,000 0,05827844 0,0823842 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05827844 0,08233583 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05827844 0,08228751 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05827844 0,08223925 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05827844 0,08219104 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05827844 0,08214289 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05827844 0,0820948 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05827844 0,08204676 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05827844 0,08199878 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05827844 0,08195086 ! cilium assembly GO:0042384 37 19 0,000 0,05827844 0,08190299 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05827844 0,08185517 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06125084 0,08597989 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06125084 0,08592975 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06125084 0,08587968 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06125084 0,08582966 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06125084 0,0857797 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,06125084 0,0857298 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,06125084 0,08567996 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06125084 0,08563017 ! response to vitamin GO:0033273 31 20 0,000 0,06125084 0,08558045 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06125084 0,08553078 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06125084 0,08548117 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06125084 0,08543161 ! response to alkaloid GO:0043279 38 20 0,000 0,06125084 0,08538211 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06125084 0,08533267 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06125084 0,08528329 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06125084 0,08523397 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06125084 0,0851847 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06125084 0,08513549 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06125084 0,08508633 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06125084 0,08503724 ! body fluid secretion GO:0007589 31 20 0,000 0,06125084 0,08498819 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06125084 0,08493921 ! peptide secretion GO:0002790 35 20 0,000 0,06125084 0,08489028 ! stem cell differentiation GO:0048863 53 20 0,000 0,06125084 0,08484141 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06125084 0,08479259 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06125084 0,08474384 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06125084 0,08469513 ! sensory perception of pain GO:0019233 30 20 0,000 0,06125084 0,08464648 ! diencephalon development GO:0021536 34 20 0,000 0,06125084 0,08459789 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06125084 0,08454936 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06125084 0,08450088 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06125084 0,08445245 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,06125084 0,08440408 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06125084 0,08435577 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06125084 0,08430751 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06125084 0,08425931 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06125084 0,08421116 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06125084 0,08416307 ! regulation of glucose import GO:0046324 29 20 0,000 0,06125084 0,08411503 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06125084 0,08406704 ! actin filament-based movement GO:0030048 43 20 0,000 0,06125084 0,08401912 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06125084 0,08397124 ! negative regulation of translation GO:0017148 29 20 0,000 0,06125084 0,08392342 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06125084 0,08387566 ! regulation of cell killing GO:0031341 42 21 0,000 0,06421397 0,08788328 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06421397 0,08783332 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06421397 0,08778341 ! hormone secretion GO:0046879 38 21 0,000 0,06421397 0,08773356 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06421397 0,08768377 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06421397 0,08763404 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06421397 0,08758436 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06421397 0,08753474 ! axis specification GO:0009798 38 21 0,000 0,06421397 0,08748517 ! ovarian follicle development GO:0001541 35 21 0,000 0,06421397 0,08743566 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06421397 0,0873862 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06421397 0,0873368 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06421397 0,08728746 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06421397 0,08723818 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06421397 0,08718894 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06421397 0,08713977 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06421397 0,08709065 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06421397 0,08704158 ! cytolysis GO:0019835 24 21 0,000 0,06421397 0,08699257 ! vasodilation GO:0042311 39 21 0,000 0,06421397 0,08694362 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06421397 0,08689472 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06421397 0,08684587 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06421397 0,08679708 ! DNA modification GO:0006304 34 21 0,000 0,06421397 0,08674835 ! collagen fibril organization GO:0030199 59 21 0,000 0,06421397 0,08669967 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06421397 0,08665104 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06421397 0,08660247 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06421397 0,08655395 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06421397 0,08650549 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06421397 0,08645708 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06421397 0,08640873 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06421397 0,08636043 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06421397 0,08631218 ! collagen catabolic process GO:0030574 28 21 0,000 0,06421397 0,08626399 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06421397 0,08621585 ! gut development GO:0048565 39 21 0,000 0,06421397 0,08616777 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06716784 0,09008128 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06716784 0,0900311 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06716784 0,08998097 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06716784 0,0899309 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06716784 0,08988088 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06716784 0,08983092 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06716784 0,08978101 ! regeneration GO:0031099 41 22 0,000 0,06716784 0,08973116 ! keratinization GO:0031424 28 22 0,000 0,06716784 0,08968136 ! sensory perception of taste GO:0050909 28 22 0,000 0,06716784 0,08963162 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06716784 0,08958194 ! vacuolar transport GO:0007034 36 22 0,000 0,06716784 0,08953231 ! lysosome organization GO:0007040 41 22 0,000 0,06716784 0,08948273 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06716784 0,08943321 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06716784 0,08938375 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06716784 0,08933434 ! fucose metabolic process GO:0006004 39 22 0,000 0,06716784 0,08928498 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06716784 0,08923568 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06716784 0,08918643 ! ureteric bud development GO:0001657 43 22 0,000 0,06716784 0,08913724 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06716784 0,0890881 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06716784 0,08903902 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06716784 0,08898999 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,06716784 0,08894101 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06716784 0,08889209 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06716784 0,08884322 ! sarcomere organization GO:0045214 30 22 0,000 0,06716784 0,08879441 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06716784 0,08874564 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06716784 0,08869694 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06716784 0,08864828 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06716784 0,08859968 ! protein stabilization GO:0050821 39 22 0,000 0,06716784 0,08855113 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07011248 0,0923826 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07011248 0,09233204 ! gluconeogenesis GO:0006094 33 23 0,000 0,07011248 0,09228153 ! viral genome replication GO:0019079 41 23 0,000 0,07011248 0,09223107 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07011248 0,09218067 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07011248 0,09213033 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07011248 0,09208004 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07011248 0,0920298 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07011248 0,09197963 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07011248 0,0919295 ! visual behavior GO:0007632 42 23 0,000 0,07011248 0,09187943 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07011248 0,09182941 ! response to ethanol GO:0045471 46 23 0,000 0,07011248 0,09177945 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07011248 0,09172954 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07011248 0,09167969 ! peroxisome organization GO:0007031 37 23 0,000 0,07011248 0,09162989 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07011248 0,09158015 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07011248 0,09153046 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07011248 0,09148082 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07011248 0,09143124 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07011248 0,09138171 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07011248 0,09133223 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07011248 0,09128281 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07011248 0,09123344 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07011248 0,09118413 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07011248 0,09113486 ! fatty acid transport GO:0015908 44 23 0,000 0,07011248 0,09108565 ! platelet activation GO:0030168 37 23 0,000 0,07011248 0,0910365 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07011248 0,0909874 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07011248 0,09093835 ! hormone transport GO:0009914 40 23 0,000 0,07011248 0,09088935 ! cell-cell recognition GO:0009988 25 23 0,000 0,07011248 0,09084041 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07011248 0,09079151 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07011248 0,09074267 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,07011248 0,09069389 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07011248 0,09064515 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07011248 0,09059647 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07304793 0,09433887 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07304793 0,09428826 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07304793 0,0942377 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07304793 0,0941872 ! vesicle docking GO:0048278 47 24 0,000 0,07304793 0,09413675 ! spinal cord development GO:0021510 47 24 0,000 0,07304793 0,09408636 ! vacuole organization GO:0007033 43 24 0,000 0,07304793 0,09403602 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07304793 0,09398573 ! digestive system process GO:0022600 39 24 0,000 0,07304793 0,0939355 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07304793 0,09388532 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07304793 0,09383519 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07304793 0,09378512 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07304793 0,0937351 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07304793 0,09368514 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07304793 0,09363522 ! membrane depolarization GO:0051899 39 24 0,000 0,07304793 0,09358537 ! pallium development GO:0021543 49 24 0,000 0,07304793 0,09353556 ! pentose metabolic process GO:0019321 35 24 0,000 0,07304793 0,09348581 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07304793 0,09343611 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07304793 0,09338646 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07304793 0,09333686 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07304793 0,09328732 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07304793 0,09323783 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07304793 0,0931884 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07304793 0,09313901 ! regulation of amine transport GO:0051952 40 24 0,000 0,07304793 0,09308968 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07597421 0,09676757 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07597421 0,09671637 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07597421 0,09666522 ! phototransduction GO:0007602 33 25 0,000 0,07597421 0,09661413 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07597421 0,09656309 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,07597421 0,09651211 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07597421 0,09646118 ! receptor metabolic process GO:0043112 46 25 0,000 0,07597421 0,0964103 ! chromosome condensation GO:0030261 45 25 0,000 0,07597421 0,09635948 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07597421 0,09630871 ! neural crest cell development GO:0014032 54 25 0,000 0,07597421 0,096258 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07597421 0,09620734 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07597421 0,09615673 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07597421 0,09610617 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07597421 0,09605567 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,07597421 0,09600522 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07597421 0,09595482 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,07597421 0,09590448 ! immunoglobulin production GO:0002377 55 25 0,000 0,07597421 0,09585419 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07597421 0,09580395 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07597421 0,09575377 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07597421 0,09570363 ! telomere organization GO:0032200 43 25 0,000 0,07597421 0,09565355 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07597421 0,09560352 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07597421 0,09555355 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07889134 0,09917062 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07889134 0,09911883 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07889134 0,0990671 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07889134 0,09901542 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07889134 0,0989638 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07889134 0,09891223 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07889134 0,09886071 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07889134 0,09880925 ! molting cycle process GO:0022404 50 26 0,000 0,07889134 0,09875784 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07889134 0,09870648 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07889134 0,09865518 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,07889134 0,09860393 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07889134 0,09855273 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07889134 0,09850159 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07889134 0,0984505 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07889134 0,09839946 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07889134 0,09834848 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07889134 0,09829755 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07889134 0,09824667 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07889134 0,09819584 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07889134 0,09814507 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07889134 0,09809435 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07889134 0,09804368 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07889134 0,09799306 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07889134 0,0979425 ! iron ion transport GO:0006826 59 27 0,000 0,08179936 0,1015004 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08179936 0,10144808 ! protein amino acid acylation GO:0043543 55 27 0,000 0,08179936 0,10139581 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08179936 0,1013436 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08179936 0,10129144 ! fat cell differentiation GO:0045444 50 27 0,000 0,08179936 0,10123934 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08179936 0,10118729 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08179936 0,10113529 ! autophagy GO:0006914 41 27 0,000 0,08179936 0,10108334 ! male gonad development GO:0008584 44 27 0,000 0,08179936 0,10103145 ! response to toxin GO:0009636 47 27 0,000 0,08179936 0,10097962 ! primary neural tube formation GO:0014020 51 27 0,000 0,08179936 0,10092783 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08179936 0,1008761 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08179936 0,10082442 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,08179936 0,1007728 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08179936 0,10072122 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08179936 0,1006697 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08179936 0,10061824 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,0846983 0,10413087 ! circadian rhythm GO:0007623 50 28 0,000 0,0846983 0,10407769 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,0846983 0,10402456 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,0846983 0,10397149 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,0846983 0,10391847 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,0846983 0,1038655 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,0846983 0,10381259 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,0846983 0,10375973 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,0846983 0,10370693 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,0846983 0,10365418 ! synaptogenesis GO:0007416 42 28 0,000 0,0846983 0,10360148 ! lipid oxidation GO:0034440 43 28 0,000 0,0846983 0,10354884 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,0846983 0,10349625 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,0846983 0,10344371 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08758818 0,10691891 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08758818 0,10686469 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08758818 0,10681053 ! catechol metabolic process GO:0009712 54 29 0,000 0,08758818 0,10675642 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08758818 0,10670237 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08758818 0,10664837 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08758818 0,10659442 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08758818 0,10654053 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08758818 0,1064867 ! cell fate determination GO:0001709 60 29 0,000 0,08758818 0,10643292 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08758818 0,10637919 ! detection of light stimulus GO:0009583 38 29 0,000 0,08758818 0,10632552 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08758818 0,1062719 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08758818 0,10621833 ! regulation of coagulation GO:0050818 46 29 0,000 0,08758818 0,10616482 ! phenol metabolic process GO:0018958 55 30 0,000 0,09046904 0,10960146 ! zinc ion transport GO:0006829 45 30 0,000 0,09046904 0,1095463 ! membrane docking GO:0022406 61 30 0,000 0,09046904 0,1094912 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,09046904 0,10943615 ! cell junction assembly GO:0034329 78 30 0,000 0,09046904 0,10938116 ! regulation of innate immune response GO:0045088 51 30 0,000 0,09046904 0,10932622 ! acute-phase response GO:0006953 49 30 0,000 0,09046904 0,10927134 ! myofibril assembly GO:0030239 47 30 0,000 0,09046904 0,10921651 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,09046904 0,10916174 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,09046904 0,10910702 ! phospholipid transport GO:0015914 51 30 0,000 0,09046904 0,10905236 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,09046904 0,10899775 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,09046904 0,1089432 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,09046904 0,1088887 ! eye morphogenesis GO:0048592 60 30 0,000 0,09046904 0,10883425 ! response to heat GO:0009408 50 30 0,000 0,09046904 0,10877986 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09334089 0,11217692 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09334089 0,11212091 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09334089 0,11206496 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09334089 0,11200907 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09334089 0,11195323 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09334089 0,11189745 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09334089 0,11184173 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09334089 0,11178605 ! ovulation cycle process GO:0022602 49 31 0,000 0,09334089 0,11173044 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09334089 0,11167488 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09334089 0,11161938 ! peptide transport GO:0015833 55 31 0,000 0,09334089 0,11156393 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09334089 0,11150853 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09334089 0,11145319 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09334089 0,11139791 ! mesoderm formation GO:0001707 69 31 0,000 0,09334089 0,11134268 ! natural killer cell activation GO:0030101 45 31 0,000 0,09334089 0,1112875 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09334089 0,11123238 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09334089 0,11117732 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09334089 0,11112231 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,09334089 0,11106735 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09334089 0,11101245 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09620377 0,11436081 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09620377 0,11430433 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09620377 0,11424791 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09620377 0,11419155 ! cholesterol transport GO:0030301 56 32 0,000 0,09620377 0,11413524 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09620377 0,11407899 ! spliceosome assembly GO:0000245 67 32 0,000 0,09620377 0,1140228 ! spindle organization GO:0007051 46 32 0,000 0,09620377 0,11396665 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09620377 0,11391057 ! metanephros development GO:0001656 74 32 0,000 0,09620377 0,11385454 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09620377 0,11379856 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09620377 0,11374264 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09620377 0,11368678 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,09620377 0,11363096 ! muscle cell development GO:0055001 49 32 0,000 0,09620377 0,11357521 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09620377 0,11351951 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09620377 0,11346386 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09620377 0,11340827 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09620377 0,11335273 ! ovulation cycle GO:0042698 51 32 0,000 0,09620377 0,11329725 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09620377 0,11324182 ! hindbrain development GO:0030902 61 32 0,000 0,09620377 0,11318644 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09620377 0,11313112 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09620377 0,11307585 ! post-embryonic development GO:0009791 69 33 0,000 0,09905771 0,11637346 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09905771 0,11631666 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09905771 0,11625992 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09905771 0,11620324 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09905771 0,11614661 ! cell fate specification GO:0001708 52 33 0,000 0,09905771 0,11609004 ! sterol transport GO:0015918 57 33 0,000 0,09905771 0,11603352 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09905771 0,11597705 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09905771 0,11592064 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09905771 0,11586429 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09905771 0,11580799 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,10190272 0,11907623 ! glial cell differentiation GO:0010001 63 34 0,000 0,10190272 0,11901842 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10190272 0,11896068 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,10190272 0,11890299 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10190272 0,11884535 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,10190272 0,11878777 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,10190272 0,11873024 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10190272 0,11867278 ! spermatid development GO:0007286 63 34 0,000 0,10190272 0,11861536 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10190272 0,11855801 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10190272 0,1185007 ! placenta development GO:0001890 53 34 0,000 0,10190272 0,11844346 ! regulation of muscle development GO:0048634 70 35 0,000 0,10473885 0,12168116 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10473885 0,12162243 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10473885 0,12156376 ! odontogenesis GO:0042476 66 35 0,000 0,10473885 0,12150515 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10473885 0,12144659 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10473885 0,12138809 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10473885 0,12132965 ! cytokine production GO:0001816 59 35 0,000 0,10473885 0,12127126 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,10473885 0,12121293 ! neural tube formation GO:0001841 67 35 0,000 0,10473885 0,12115465 ! vesicle localization GO:0051648 64 35 0,000 0,10473885 0,12109643 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10756612 0,12430551 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,10756612 0,12424584 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10756612 0,12418622 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10756612 0,12412666 ! cell junction organization GO:0034330 86 36 0,000 0,10756612 0,12406715 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10756612 0,12400771 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,10756612 0,12394831 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10756612 0,12388898 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10756612 0,1238297 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10756612 0,12377048 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10756612 0,12371132 ! aerobic respiration GO:0009060 55 36 0,000 0,10756612 0,12365221 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,10756612 0,12359316 ! embryonic organ development GO:0048568 57 36 0,000 0,10756612 0,12353417 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10756612 0,12347523 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11038455 0,12665008 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11038455 0,12658972 ! meiosis I GO:0007127 65 37 0,000 0,11038455 0,12652941 ! sister chromatid segregation GO:0000819 58 37 0,000 0,11038455 0,12646915 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11038455 0,12640896 ! organic anion transport GO:0015711 68 37 0,000 0,11038455 0,12634882 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,11038455 0,12628874 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11038455 0,12622872 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11038455 0,12616875 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11038455 0,12610884 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,11038455 0,12604899 ! spermatid differentiation GO:0048515 66 37 0,000 0,11038455 0,1259892 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11319417 0,12913475 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11319417 0,12907354 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11319417 0,1290124 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11319417 0,12895132 ! nucleus organization GO:0006997 67 38 0,000 0,11319417 0,12889029 ! lipid homeostasis GO:0055088 67 38 0,000 0,11319417 0,12882932 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11319417 0,12876841 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11319417 0,12870755 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11319417 0,12864675 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11319417 0,12858601 ! mRNA catabolic process GO:0006402 71 39 0,000 0,11599502 0,13170552 ! learning GO:0007612 77 39 0,000 0,11599502 0,1316434 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11599502 0,13158133 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11599502 0,13151932 ! segmentation GO:0035282 67 39 0,000 0,11599502 0,13145737 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11599502 0,13139548 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11599502 0,13133365 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11599502 0,13127188 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11878711 0,13436849 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,11878711 0,13430535 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11878711 0,13424226 ! feeding behavior GO:0007631 59 40 0,000 0,11878711 0,13417924 ! negative regulation of binding GO:0051100 72 40 0,000 0,11878711 0,13411627 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11878711 0,13405337 ! mesenchymal cell development GO:0014031 87 40 0,000 0,11878711 0,13399052 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11878711 0,13392773 ! maintenance of protein location GO:0045185 91 40 0,000 0,11878711 0,133865 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12157047 0,13693752 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,12157047 0,13687344 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,12157047 0,13680942 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,12157047 0,13674546 ! gliogenesis GO:0042063 88 41 0,000 0,12157047 0,13668156 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,12157047 0,13661772 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,12157047 0,13655394 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,12157047 0,13649022 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,12434513 0,13954029 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,12434513 0,13947524 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,12434513 0,13941025 ! regulation of tube size GO:0035150 71 42 0,000 0,12434513 0,13934531 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,12434513 0,13928044 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12434513 0,13921563 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12434513 0,13915088 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12434513 0,13908619 ! neuron migration GO:0001764 79 42 0,000 0,12434513 0,13902156 ! regulation of protein secretion GO:0050708 71 42 0,000 0,12434513 0,13895699 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,12434513 0,13889247 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12711113 0,14191618 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12711113 0,14185036 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12711113 0,14178459 ! glucose transport GO:0015758 65 43 0,000 0,12711113 0,14171889 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12711113 0,14165325 ! neural tube development GO:0021915 77 43 0,000 0,12711113 0,14158767 ! striated muscle contraction GO:0006941 77 43 0,000 0,12711113 0,14152215 ! phagocytosis GO:0006909 90 43 0,000 0,12711113 0,14145669 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12711113 0,14139129 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12986847 0,14439166 ! hexose transport GO:0008645 67 44 0,000 0,12986847 0,14432496 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12986847 0,14425833 ! male sex differentiation GO:0046661 76 44 0,000 0,12986847 0,14419176 ! biopolymer methylation GO:0043414 84 44 0,000 0,12986847 0,14412525 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12986847 0,1440588 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,12986847 0,14399242 ! maintenance of location in cell GO:0051651 97 44 0,000 0,12986847 0,14392609 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,1326172 0,14690469 ! glycolysis GO:0006096 65 45 0,000 0,1326172 0,14683708 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,1326172 0,14676954 ! leukocyte migration GO:0050900 68 45 0,000 0,1326172 0,14670206 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,1326172 0,14663464 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,1326172 0,14656729 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,1326172 0,14649999 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,1326172 0,14643276 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,1326172 0,14636559 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,1326172 0,14629848 ! cell growth GO:0016049 84 45 0,000 0,1326172 0,14623143 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13535734 0,14918449 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,13535734 0,14911619 ! pigmentation GO:0043473 100 46 0,000 0,13535734 0,14904794 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,13535734 0,14897976 ! positive regulation of defense response GO:0031349 76 47 0,000 0,13808891 0,15191674 ! response to calcium ion GO:0051592 81 47 0,000 0,13808891 0,15184731 ! endosome transport GO:0016197 108 47 0,000 0,13808891 0,15177794 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,13808891 0,15170863 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13808891 0,15163939 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13808891 0,15157021 ! JNK cascade GO:0007254 91 47 0,000 0,13808891 0,1515011 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13808891 0,15143205 ! methylation GO:0032259 90 47 0,000 0,13808891 0,15136306 ! protein homooligomerization GO:0051260 76 47 0,000 0,13808891 0,15129413 ! cellular component disassembly GO:0022411 86 48 0,000 0,14081194 0,15420734 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,14081194 0,15413718 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,14081194 0,15406709 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14081194 0,15399706 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14081194 0,15392709 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,14081194 0,15385718 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,14352646 0,156752 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,14352646 0,15668088 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,14352646 0,15660982 ! regulation of ion transport GO:0043269 77 49 0,000 0,14352646 0,15653883 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,14352646 0,1564679 ! peptide metabolic process GO:0006518 76 49 0,000 0,14352646 0,15639704 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14352646 0,15632624 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,14352646 0,1562555 ! endocrine system development GO:0035270 104 49 0,000 0,14352646 0,15618483 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,14352646 0,15611422 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14352646 0,15604368 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,14352646 0,15597319 ! regulation of ossification GO:0030278 117 50 0,000 0,14623249 0,15884215 ! histone modification GO:0016570 91 50 0,000 0,14623249 0,15877047 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,14623249 0,15869886 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14623249 0,15862731 ! positive regulation of binding GO:0051099 78 51 0,000 0,14893006 0,16148072 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,14893006 0,16140799 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,14893006 0,16133531 ! excretion GO:0007588 83 51 0,000 0,14893006 0,1612627 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,14893006 0,16119016 ! chromatin remodeling GO:0006338 109 51 0,000 0,14893006 0,16111768 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,14893006 0,16104527 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,14893006 0,16097292 ! vesicle organization GO:0016050 107 51 0,000 0,14893006 0,16090064 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,14893006 0,16082842 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,1516192 0,16365895 ! membrane fusion GO:0006944 110 52 0,000 0,1516192 0,16358556 ! covalent chromatin modification GO:0016569 101 52 0,000 0,1516192 0,16351223 ! amino acid activation GO:0043038 92 52 0,000 0,1516192 0,16343898 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,1516192 0,16336578 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,15429993 0,16617978 ! RNA catabolic process GO:0006401 93 53 0,000 0,15429993 0,16610543 ! regulation of translational initiation GO:0006446 82 53 0,000 0,15429993 0,16603114 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,15429993 0,16595692 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,15429993 0,16588277 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,15429993 0,16580868 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,15429993 0,16573466 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,15697228 0,16852981 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,15697228 0,16845464 ! cell recognition GO:0008037 85 54 0,000 0,15697228 0,16837954 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15697228 0,1683045 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15697228 0,16822953 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15697228 0,16815463 ! glucose catabolic process GO:0006007 82 55 0,000 0,15963627 0,1709323 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,15963627 0,17085626 ! gastrulation GO:0007369 112 55 0,000 0,15963627 0,17078029 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,15963627 0,17070439 ! RNA elongation GO:0006354 79 55 0,000 0,15963627 0,17062855 ! nuclear export GO:0051168 97 55 0,000 0,15963627 0,17055279 ! regulation of actin filament length GO:0030832 105 56 0,000 0,16229194 0,17331309 ! sensory perception of smell GO:0007608 80 56 0,000 0,16229194 0,1732362 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,16229194 0,17315938 ! proton transport GO:0015992 94 56 0,000 0,16229194 0,17308262 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,16229194 0,17300594 ! maintenance of location GO:0051235 118 57 0,000 0,1649393 0,1757502 ! hydrogen transport GO:0006818 97 58 0,000 0,16757838 0,17848321 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16757838 0,17840424 ! adult behavior GO:0030534 99 58 0,000 0,16757838 0,17832533 ! positive regulation of secretion GO:0051047 95 59 0,000 0,1702092 0,1810448 ! regulation of cellular component size GO:0032535 109 59 0,000 0,1702092 0,1809648 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,1702092 0,18088487 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1702092 0,18080501 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,1702092 0,18072522 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,1702092 0,1806455 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,17283181 0,18334803 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,17283181 0,18326722 ! regulation of heart contraction GO:0008016 110 60 0,000 0,17283181 0,18318649 ! camera-type eye development GO:0043010 116 60 0,000 0,17283181 0,18310582 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,17283181 0,18302523 ! kidney development GO:0001822 122 60 0,000 0,17283181 0,18294471 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,1754462 0,18563042 ! mesoderm development GO:0007498 119 61 0,000 0,1754462 0,18554882 ! tRNA processing GO:0008033 89 61 0,000 0,1754462 0,1854673 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,1754462 0,18538584 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17805243 0,18805713 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,1806505 0,19071746 ! detection of external stimulus GO:0009581 91 63 0,000 0,1806505 0,19063381 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,1806505 0,19055024 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,1806505 0,19046674 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,18324044 0,19311279 ! cell redox homeostasis GO:0045454 102 64 0,000 0,18324044 0,19302824 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,18324044 0,19294376 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,18324044 0,19285936 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,18324044 0,19277503 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18582229 0,19540578 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18582229 0,19532041 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,18582229 0,19523512 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,18839605 0,19785286 ! actin filament organization GO:0007015 148 66 0,000 0,18839605 0,19776654 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,18839605 0,19768029 ! extracellular matrix organization GO:0030198 133 66 0,000 0,18839605 0,19759412 ! secondary metabolic process GO:0019748 116 66 0,000 0,18839605 0,19750802 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,19096177 0,20011064 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,19096177 0,20002352 ! chromosome segregation GO:0007059 113 67 0,000 0,19096177 0,19993648 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,19096177 0,19984951 ! hexose catabolic process GO:0019320 104 67 0,000 0,19096177 0,19976262 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,19096177 0,1996758 ! activation of immune response GO:0002253 105 67 0,000 0,19096177 0,19958906 ! amino acid transport GO:0006865 125 68 0,000 0,19351946 0,20217448 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,19351946 0,20208673 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,19351946 0,20199906 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,19351946 0,20191146 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,19351946 0,20182394 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,19351946 0,20173649 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,19606915 0,20430593 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,19606915 0,20421748 ! urogenital system development GO:0001655 137 69 0,000 0,19606915 0,20412911 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19606915 0,20404082 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19606915 0,20395261 ! antigen processing and presentation GO:0019882 104 69 0,000 0,19606915 0,20386447 ! appendage morphogenesis GO:0035107 135 70 0,000 0,19861087 0,20641803 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,20114463 0,20896113 ! appendage development GO:0048736 136 71 0,000 0,20114463 0,20887095 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,20114463 0,20878084 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,20114463 0,20869081 ! regulation of immune effector process GO:0002697 137 71 0,000 0,20114463 0,20860085 ! acute inflammatory response GO:0002526 113 72 0,000 0,20367047 0,21112932 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,20367047 0,21103839 ! carbohydrate transport GO:0008643 110 72 0,000 0,20367047 0,21094754 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,20367047 0,21085677 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,20367047 0,21076608 ! learning or memory GO:0007611 147 73 0,000 0,2061884 0,21328 ! regulation of blood pressure GO:0008217 125 73 0,000 0,2061884 0,21318835 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,2061884 0,21309677 ! fertilization GO:0009566 90 73 0,000 0,2061884 0,21300528 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,20869845 0,21550579 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,20869845 0,21541333 ! neurotransmitter transport GO:0006836 123 74 0,000 0,20869845 0,21532096 ! exocytosis GO:0006887 133 74 0,000 0,20869845 0,21522867 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,20869845 0,21513645 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,20869845 0,21504432 ! eye development GO:0001654 143 74 0,000 0,20869845 0,21495226 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,21120066 0,21743636 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,21120066 0,21734336 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,21120066 0,21725044 ! rhythmic process GO:0048511 128 75 0,000 0,21120066 0,2171576 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,21369503 0,21962847 ! defense response to bacterium GO:0042742 89 76 0,000 0,21369503 0,21953469 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,21369503 0,21944099 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,21369503 0,21934737 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,2161816 0,22180508 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,2161816 0,22171054 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,2161816 0,22161607 ! blood coagulation GO:0007596 146 78 0,000 0,21866038 0,2240617 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,21866038 0,22396632 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,21866038 0,22387101 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,22113141 0,22630463 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,22113141 0,22620841 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,22113141 0,22611227 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,22113141 0,22601622 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,22113141 0,22592025 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,22359471 0,22833993 ! response to metal ion GO:0010038 140 80 0,000 0,22359471 0,22824305 ! muscle cell differentiation GO:0042692 159 80 0,000 0,22359471 0,22814626 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,22359471 0,22804954 ! digestion GO:0007586 112 81 0,000 0,2260503 0,23045636 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,2260503 0,23035875 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,2260503 0,23026123 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,2284982 0,23265623 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,2284982 0,23255781 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,2284982 0,23245948 ! regulation of lyase activity GO:0051339 160 83 0,000 0,23093844 0,23484273 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,23337105 0,2372162 ! hemostasis GO:0007599 158 84 0,000 0,23337105 0,23711602 ! regulation of ligase activity GO:0051340 142 84 0,000 0,23337105 0,23701593 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,23337105 0,23691592 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,23579604 0,23927679 ! amine biosynthetic process GO:0009309 138 86 0,000 0,23821344 0,24162797 ! response to inorganic substance GO:0010035 153 86 0,000 0,23821344 0,24152614 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,23821344 0,2414244 ! alcohol catabolic process GO:0046164 130 86 0,000 0,23821344 0,24132275 ! amine transport GO:0015837 155 86 0,000 0,23821344 0,24122118 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,24062327 0,24355894 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,24062327 0,24345652 ! cellular respiration GO:0045333 135 88 0,000 0,24302556 0,24578374 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,24302556 0,24568047 ! regulation of DNA binding GO:0051101 155 88 0,000 0,24302556 0,24557728 ! regulation of neurological system process GO:0031644 148 88 0,000 0,24302556 0,24547418 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,24302556 0,24537117 ! cellular defense response GO:0006968 114 89 0,000 0,24542033 0,24768512 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,24780761 0,24998956 ! sterol metabolic process GO:0016125 152 91 0,000 0,25018741 0,25228454 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,25018741 0,25217885 ! regulation of defense response GO:0031347 149 92 0,000 0,25255976 0,25446348 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,25255976 0,25435696 ! vitamin metabolic process GO:0006766 139 92 0,000 0,25255976 0,25425054 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,25492468 0,25652396 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,25492468 0,25641672 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,25492468 0,25630956 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,2572822 0,25857184 ! transcription initiation GO:0006352 153 94 0,000 0,2572822 0,25846387 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,25963234 0,26071595 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,26197512 0,26295876 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,26197512 0,2628491 ! positive regulation of immune response GO:0050778 156 96 0,000 0,26197512 0,26273953 ! detection of stimulus GO:0051606 151 96 0,000 0,26197512 0,26263006 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,26431056 0,26486098 ! hormone metabolic process GO:0042445 157 97 0,000 0,26431056 0,26475071 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,2666387 0,26697158 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,2666387 0,26686052 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,26895954 0,26907137 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,26895954 0,26895954