pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6551-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of anatomical structure morphogenesis GO:0022603 90 86 6,000 3,435E-07 6,331E-04 ! axonogenesis GO:0007409 66 62 5,000 9,228E-07 8,504E-04 ! response to peptide hormone stimulus GO:0043434 36 34 4,000 9,694E-07 5,955E-04 ! insulin receptor signaling pathway GO:0008286 17 15 3,000 1,034E-06 4,765E-04 ! positive regulation of cell migration GO:0030335 36 36 4,000 1,303E-06 4,802E-04 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 5,000 1,468E-06 4,51E-04 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! T cell lineage commitment GO:0002360 5 5 2,000 1,543E-06 4,063E-04 ! cell part morphogenesis GO:0032990 75 70 5,000 1,906E-06 4,391E-04 ! positive regulation of cell motion GO:0051272 39 39 4,000 1,966E-06 4,026E-04 ! regulation of cell migration GO:0030334 71 71 5,000 2,074E-06 3,822E-04 ! ER overload response GO:0006983 6 6 2,000 3,074E-06 5,151E-04 ! focal adhesion formation GO:0048041 7 6 2,000 3,074E-06 4,722E-04 ! peptidyl-serine phosphorylation GO:0018105 6 6 2,000 3,074E-06 4,359E-04 ! cell morphogenesis involved in differentiation GO:0000904 82 77 5,000 3,351E-06 4,412E-04 ! regulation of locomotion GO:0040012 79 79 5,000 3,898E-06 4,789E-04 ! regulation of cell motion GO:0051270 79 79 5,000 3,898E-06 4,49E-04 ! neuron projection development GO:0031175 85 80 5,000 4,197E-06 4,55E-04 ! cellular response to insulin stimulus GO:0032869 23 21 3,000 4,428E-06 4,534E-04 ! response to gamma radiation GO:0010332 8 7 2,000 5,36E-06 5,199E-04 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 6,41E-06 5,907E-04 ! positive regulation of transferase activity GO:0051347 91 88 5,000 7,33E-06 6,433E-04 GO:0033674|positive regulation of kinase activity, ! negative regulation of bone remodeling GO:0046851 8 8 2,000 8,543E-06 7,156E-04 ! peptidyl-serine modification GO:0018209 8 8 2,000 8,543E-06 6,845E-04 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 8,543E-06 6,56E-04 ! response to insulin stimulus GO:0032868 28 26 3,000 1,084E-05 7,994E-04 ! negative regulation of tissue remodeling GO:0034104 9 9 2,000 1,277E-05 9,049E-04 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 1,473E-05 1,006E-03 ! peptidyl-amino acid modification GO:0018193 61 59 4,000 1,578E-05 1,038E-03 ! response to UV GO:0009411 29 29 3,000 1,702E-05 1,082E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 1,817E-05 1,116E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 1,817E-05 1,08E-03 ! negative regulation of homeostatic process GO:0032845 10 10 2,000 1,817E-05 1,046E-03 ! activation of MAPKK activity GO:0000186 12 11 2,000 2,488E-05 1,39E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 2,488E-05 1,349E-03 ! hindbrain development GO:0030902 11 11 2,000 2,488E-05 1,31E-03 ! regulation of angiogenesis GO:0045765 35 34 3,000 3,259E-05 1,668E-03 ! vasculogenesis GO:0001570 13 13 2,000 4,28E-05 2,132E-03 ! mitochondrial membrane organization GO:0007006 13 13 2,000 4,28E-05 2,076E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 4,28E-05 2,023E-03 ! cell aging GO:0007569 13 13 2,000 4,28E-05 1,972E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 4,28E-05 1,924E-03 ! protein tetramerization GO:0051262 13 13 2,000 4,28E-05 1,878E-03 ! cell-matrix adhesion GO:0007160 39 38 3,000 5,106E-05 2,188E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 5,427E-05 2,273E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 6,758E-05 2,768E-03 ! response to ionizing radiation GO:0010212 16 15 2,000 6,758E-05 2,708E-03 ! tube development GO:0035295 83 81 4,000 7,393E-05 2,899E-03 ! cell-substrate adhesion GO:0031589 43 42 3,000 7,62E-05 2,926E-03 ! blood vessel morphogenesis GO:0048514 84 83 4,000 8,311E-05 3,126E-03 ! cell junction assembly GO:0034329 18 17 2,000 1,002E-04 3,694E-03 ! negative regulation of cell development GO:0010721 18 17 2,000 1,002E-04 3,622E-03 GO:0050768|negative regulation of neurogenesis, ! heart development GO:0007507 90 87 4,000 1,041E-04 3,689E-03 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 1,094E-04 3,803E-03 ! B cell differentiation GO:0030183 18 18 2,000 1,198E-04 4,089E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 1,403E-04 4,702E-03 ! blood vessel development GO:0001568 95 94 4,000 1,503E-04 4,948E-03 ! regulation of neurogenesis GO:0050767 51 50 3,000 1,519E-04 4,912E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 1,642E-04 5,217E-03 GO:0051325|interphase, ! vasculature development GO:0001944 97 96 4,000 1,661E-04 5,188E-03 ! response to light stimulus GO:0009416 53 52 3,000 1,772E-04 5,442E-03 ! response to hypoxia GO:0001666 53 53 3,000 1,909E-04 5,767E-03 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 1,931E-04 5,739E-03 ! response to hormone stimulus GO:0009725 102 100 4,000 2,013E-04 5,889E-03 ! response to oxygen levels GO:0070482 55 54 3,000 2,053E-04 5,913E-03 ! negative regulation of multicellular organismal process GO:0051241 55 54 3,000 2,053E-04 5,822E-03 ! cell junction organization GO:0034330 23 22 2,000 2,227E-04 6,219E-03 ! regulation of nervous system development GO:0051960 57 56 3,000 2,366E-04 6,508E-03 ! positive regulation of growth GO:0045927 23 23 2,000 2,551E-04 6,915E-03 ! regulation of cell development GO:0060284 60 59 3,000 2,897E-04 7,738E-03 ! mitochondrial transport GO:0006839 24 24 2,000 2,905E-04 7,648E-03 ! T cell differentiation GO:0030217 24 24 2,000 2,905E-04 7,54E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 2,94E-04 7,525E-03 ! metencephalon development GO:0022037 5 5 1,000 2,94E-04 7,422E-03 ! mRNA stabilization GO:0048255 5 5 1,000 2,94E-04 7,322E-03 GO:0043489|RNA stabilization, ! endocrine pancreas development GO:0031018 5 5 1,000 2,94E-04 7,224E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 2,94E-04 7,129E-03 ! fear response GO:0042596 5 5 1,000 2,94E-04 7,036E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 2,94E-04 6,946E-03 ! response to UV-B GO:0010224 5 5 1,000 2,94E-04 6,858E-03 ! neuron recognition GO:0008038 5 5 1,000 2,94E-04 6,773E-03 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 2,94E-04 6,689E-03 ! cellular pigmentation GO:0033059 5 5 1,000 2,94E-04 6,607E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 2,94E-04 6,528E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 2,94E-04 6,45E-03 ! oocyte differentiation GO:0009994 5 5 1,000 2,94E-04 6,374E-03 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 2,94E-04 6,3E-03 ! spleen development GO:0048536 5 5 1,000 2,94E-04 6,228E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 2,94E-04 6,157E-03 ! response to nicotine GO:0035094 5 5 1,000 2,94E-04 6,088E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 3,288E-04 6,733E-03 ! negative regulation of cell migration GO:0030336 26 26 2,000 3,703E-04 7,499E-03 ! angiogenesis GO:0001525 65 64 3,000 3,965E-04 7,944E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 4,394E-04 8,708E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 4,394E-04 8,616E-03 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 4,394E-04 8,525E-03 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 4,394E-04 8,436E-03 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 4,394E-04 8,349E-03 ! negative regulation of ossification GO:0030279 6 6 1,000 4,394E-04 8,264E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 4,394E-04 8,181E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 4,394E-04 8,099E-03 ! negative regulation of axonogenesis GO:0050771 7 6 1,000 4,394E-04 8,019E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 4,394E-04 7,94E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 4,394E-04 7,863E-03 ! thymus development GO:0048538 6 6 1,000 4,394E-04 7,787E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 4,394E-04 7,713E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 4,394E-04 7,64E-03 ! localization within membrane GO:0051668 6 6 1,000 4,394E-04 7,569E-03 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 4,463E-04 7,615E-03 ! response to radiation GO:0009314 70 68 3,000 5,003E-04 8,459E-03 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 5,145E-04 8,62E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 5,145E-04 8,542E-03 ! response to nutrient levels GO:0031667 69 69 3,000 5,29E-04 8,704E-03 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 5,29E-04 8,627E-03 ! response to reactive oxygen species GO:0000302 31 30 2,000 5,695E-04 9,207E-03 ! hair follicle morphogenesis GO:0031069 7 7 1,000 6,131E-04 9,825E-03 ! digestive system development GO:0055123 7 7 1,000 6,131E-04 9,74E-03 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 6,131E-04 9,657E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 6,131E-04 9,575E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! axon cargo transport GO:0008088 7 7 1,000 6,131E-04 9,495E-03 ! eating behavior GO:0042755 7 7 1,000 6,131E-04 9,416E-03 ! cranial nerve development GO:0021545 7 7 1,000 6,131E-04 9,338E-03 ! autonomic nervous system development GO:0048483 7 7 1,000 6,131E-04 9,261E-03 ! negative regulation of cell projection organization GO:0031345 8 7 1,000 6,131E-04 9,186E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 6,131E-04 9,112E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 6,131E-04 9,039E-03 ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 6,131E-04 8,967E-03 ! response to X-ray GO:0010165 7 7 1,000 6,131E-04 8,897E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 6,131E-04 8,827E-03 ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 6,131E-04 8,759E-03 ! regulation of mRNA stability GO:0043488 7 7 1,000 6,131E-04 8,691E-03 ! regulation of axon extension GO:0030516 7 7 1,000 6,131E-04 8,625E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 6,131E-04 8,56E-03 ! response to extracellular stimulus GO:0009991 72 72 3,000 6,221E-04 8,62E-03 ! B cell activation GO:0042113 31 31 2,000 6,281E-04 8,639E-03 ! aging GO:0007568 32 31 2,000 6,281E-04 8,575E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 6,281E-04 8,512E-03 ! negative regulation of cell motion GO:0051271 31 31 2,000 6,281E-04 8,449E-03 ! negative regulation of cell growth GO:0030308 32 32 2,000 6,904E-04 9,221E-03 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 6,904E-04 9,154E-03 ! negative regulation of cell size GO:0045792 33 33 2,000 7,566E-04 9,96E-03 ! activation of protein kinase activity GO:0032147 35 33 2,000 7,566E-04 9,889E-03 ! regulation of neuron differentiation GO:0045664 34 33 2,000 7,566E-04 9,82E-03 ! regulation of neuron apoptosis GO:0043523 34 33 2,000 7,566E-04 9,751E-03 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 8,146E-04 0,01042537 ! adult walking behavior GO:0007628 8 8 1,000 8,146E-04 0,01035347 ! pancreas development GO:0031016 8 8 1,000 8,146E-04 0,01028256 ! T cell selection GO:0045058 8 8 1,000 8,146E-04 0,01021261 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 8,146E-04 0,0101436 ! sex determination GO:0007530 8 8 1,000 8,146E-04 0,01007553 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 8,146E-04 0,01000836 ! plasma membrane fusion GO:0045026 8 8 1,000 8,146E-04 9,942E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 8,146E-04 9,877E-03 ! alpha-beta T cell activation GO:0046631 8 8 1,000 8,146E-04 9,812E-03 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 8,146E-04 9,748E-03 ! T cell homeostasis GO:0043029 8 8 1,000 8,146E-04 9,686E-03 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 8,146E-04 9,623E-03 ! regulation of RNA stability GO:0043487 8 8 1,000 8,146E-04 9,562E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 8,146E-04 9,502E-03 ! regulation of bone remodeling GO:0046850 34 34 2,000 8,267E-04 9,582E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 9,007E-04 0,01037518 ! regulation of cell morphogenesis GO:0022604 38 35 2,000 9,007E-04 0,01031074 ! regulation of tissue remodeling GO:0034103 35 35 2,000 9,007E-04 0,01024709 ! MAPKKK cascade GO:0000165 82 81 3,000 9,709E-04 0,01097765 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,044E-03 0,01172842 ! response to alkaloid GO:0043279 10 9 1,000 1,044E-03 0,01165734 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,044E-03 0,01158712 ! response to ethanol GO:0045471 9 9 1,000 1,044E-03 0,01151773 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,044E-03 0,01144917 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 1,044E-03 0,01138143 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,044E-03 0,01131448 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 9 9 1,000 1,044E-03 0,01124831 ! regulation of cellular pH GO:0030641 9 9 1,000 1,044E-03 0,01118291 ! histone acetylation GO:0016573 9 9 1,000 1,044E-03 0,01111827 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,044E-03 0,01105437 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,044E-03 0,01099121 ! defense response to virus GO:0051607 9 9 1,000 1,044E-03 0,01092876 ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 1,061E-03 0,01104963 ! response to drug GO:0042493 37 37 2,000 1,061E-03 0,01098755 ! lung development GO:0030324 38 37 2,000 1,061E-03 0,01092617 ! negative regulation of growth GO:0045926 37 37 2,000 1,061E-03 0,01086547 ! negative regulation of kinase activity GO:0033673 38 38 2,000 1,148E-03 0,01168706 ! axon guidance GO:0007411 39 38 2,000 1,148E-03 0,01162284 ! regulation of homeostatic process GO:0032844 38 38 2,000 1,148E-03 0,01155933 ! respiratory tube development GO:0030323 40 39 2,000 1,239E-03 0,01240725 ! respiratory system development GO:0060541 40 39 2,000 1,239E-03 0,01234018 ! lymphocyte differentiation GO:0030098 39 39 2,000 1,239E-03 0,01227384 ! protein oligomerization GO:0051259 39 39 2,000 1,239E-03 0,0122082 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,3E-03 0,01274445 ! centrosome cycle GO:0007098 10 10 1,000 1,3E-03 0,01267702 ! epidermis morphogenesis GO:0048730 10 10 1,000 1,3E-03 0,0126103 ! neuromuscular junction development GO:0007528 10 10 1,000 1,3E-03 0,01254427 ! regulation of protein binding GO:0043393 11 10 1,000 1,3E-03 0,01247894 ! synaptic vesicle transport GO:0048489 11 10 1,000 1,3E-03 0,01241428 ! gland morphogenesis GO:0022612 10 10 1,000 1,3E-03 0,01235029 ! lymphocyte homeostasis GO:0002260 10 10 1,000 1,3E-03 0,01228696 ! nerve development GO:0021675 10 10 1,000 1,3E-03 0,01222427 ! gut development GO:0048565 10 10 1,000 1,3E-03 0,01216221 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,3E-03 0,01210079 ! negative regulation of coagulation GO:0050819 11 10 1,000 1,3E-03 0,01203998 ! negative regulation of transferase activity GO:0051348 40 40 2,000 1,334E-03 0,01229333 ! negative regulation of cell cycle GO:0045786 92 91 3,000 1,499E-03 0,01374744 ! signal complex assembly GO:0007172 11 11 1,000 1,583E-03 0,01444653 ! microtubule-based transport GO:0010970 11 11 1,000 1,583E-03 0,01437537 ! protein amino acid acetylation GO:0006473 11 11 1,000 1,583E-03 0,0143049 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 1,583E-03 0,01423512 GO:0032388|positive regulation of intracellular transport, ! dendrite development GO:0016358 11 11 1,000 1,583E-03 0,01416602 ! regulation of viral genome replication GO:0045069 11 11 1,000 1,583E-03 0,01409758 ! cellular response to starvation GO:0009267 11 11 1,000 1,583E-03 0,01402981 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 1,583E-03 0,01396268 ! G1/S transition checkpoint GO:0031575 12 11 1,000 1,583E-03 0,01389619 ! interaction with host GO:0051701 11 11 1,000 1,583E-03 0,01383033 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,583E-03 0,01376509 ! oogenesis GO:0048477 11 11 1,000 1,583E-03 0,01370047 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 1,583E-03 0,01363645 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 1,583E-03 0,01357302 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,583E-03 0,01351018 ! mitochondrion organization GO:0007005 44 43 2,000 1,647E-03 0,01399194 ! pattern specification process GO:0007389 96 94 3,000 1,691E-03 0,0142924 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 1,88E-03 0,01582062 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 1,893E-03 0,01586208 ! microtubule organizing center organization GO:0031023 12 12 1,000 1,893E-03 0,0157903 GO:0051297|centrosome organization, ! male gonad development GO:0008584 12 12 1,000 1,893E-03 0,01571918 ! renal system process GO:0003014 12 12 1,000 1,893E-03 0,01564869 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 1,893E-03 0,01557883 ! somitogenesis GO:0001756 13 12 1,000 1,893E-03 0,01550959 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 1,893E-03 0,01544096 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 1,893E-03 0,01537294 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 1,971E-03 0,01593413 ! tube morphogenesis GO:0035239 47 46 2,000 2,003E-03 0,01612393 ! regulation of membrane potential GO:0042391 46 46 2,000 2,003E-03 0,01605382 ! positive regulation of DNA replication GO:0045740 14 13 1,000 2,23E-03 0,01779133 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 2,23E-03 0,01771464 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 2,23E-03 0,01763861 ! regeneration GO:0031099 13 13 1,000 2,23E-03 0,01756323 ! post-embryonic development GO:0009791 14 13 1,000 2,23E-03 0,0174885 ! patterning of blood vessels GO:0001569 13 13 1,000 2,23E-03 0,01741439 ! negative regulation of DNA replication GO:0008156 13 13 1,000 2,23E-03 0,01734092 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 2,23E-03 0,01726805 GO:0051384|response to glucocorticoid stimulus, ! actin filament bundle formation GO:0051017 13 13 1,000 2,23E-03 0,0171958 ! ureteric bud development GO:0001657 13 13 1,000 2,23E-03 0,01712415 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 2,23E-03 0,0170531 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,23E-03 0,01698263 ! regulation of viral reproduction GO:0050792 13 13 1,000 2,23E-03 0,01691274 ! regulation of axonogenesis GO:0050770 14 13 1,000 2,23E-03 0,01684343 ! positive regulation of locomotion GO:0040017 13 13 1,000 2,23E-03 0,01677468 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,23E-03 0,01670649 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 2,23E-03 0,01663885 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 1,000 2,23E-03 0,01657176 ! tissue homeostasis GO:0001894 13 13 1,000 2,23E-03 0,01650521 GO:0048871|multicellular organismal homeostasis, ! actin filament organization GO:0007015 50 48 2,000 2,265E-03 0,01670089 ! leukocyte differentiation GO:0002521 50 49 2,000 2,404E-03 0,01765201 ! gland development GO:0048732 51 49 2,000 2,404E-03 0,01758197 ! cell cycle arrest GO:0007050 49 49 2,000 2,404E-03 0,01751247 ! skeletal muscle tissue development GO:0007519 50 49 2,000 2,404E-03 0,01744353 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 2,000 2,404E-03 0,01737512 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 2,548E-03 0,01834216 ! T cell activation GO:0042110 51 50 2,000 2,548E-03 0,01827079 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 2,548E-03 0,01819997 ! protein amino acid acylation GO:0043543 14 14 1,000 2,593E-03 0,01844824 ! regulation of neuron projection development GO:0010975 15 14 1,000 2,593E-03 0,01837728 ! hair cycle GO:0042633 14 14 1,000 2,593E-03 0,01830687 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! response to retinoic acid GO:0032526 14 14 1,000 2,593E-03 0,018237 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 1,000 2,593E-03 0,01816765 ! regulation of behavior GO:0050795 14 14 1,000 2,593E-03 0,01809884 ! base-excision repair GO:0006284 14 14 1,000 2,593E-03 0,01803054 ! response to organic cyclic substance GO:0014070 15 14 1,000 2,593E-03 0,01796276 ! regulation of blood coagulation GO:0030193 15 14 1,000 2,593E-03 0,01789548 ! cell fate commitment GO:0045165 52 52 2,000 2,851E-03 0,0196062 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 2,981E-03 0,02042388 ! response to vitamin GO:0033273 15 15 1,000 2,981E-03 0,02034823 ! ovarian follicle development GO:0001541 15 15 1,000 2,981E-03 0,02027315 ! response to starvation GO:0042594 15 15 1,000 2,981E-03 0,02019862 ! leukocyte homeostasis GO:0001776 15 15 1,000 2,981E-03 0,02012463 ! negative regulation of cell activation GO:0050866 15 15 1,000 2,981E-03 0,02005118 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 3,176E-03 0,02128273 ! regulation of cell adhesion GO:0030155 56 55 2,000 3,346E-03 0,02234405 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 3,346E-03 0,02226339 ! learning GO:0007612 16 16 1,000 3,395E-03 0,02250744 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 3,395E-03 0,02242677 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 3,395E-03 0,02234667 ! segmentation GO:0035282 17 16 1,000 3,395E-03 0,02226715 ! positive regulation of cell development GO:0010720 16 16 1,000 3,395E-03 0,02218819 ! lymphocyte proliferation GO:0046651 16 16 1,000 3,395E-03 0,02210978 ! cellular response to nutrient levels GO:0031669 16 16 1,000 3,395E-03 0,02203193 ! positive regulation of catabolic process GO:0009896 16 16 1,000 3,395E-03 0,02195463 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 3,395E-03 0,02187786 ! regulation of coagulation GO:0050818 17 16 1,000 3,395E-03 0,02180163 ! reproductive developmental process GO:0003006 56 56 2,000 3,522E-03 0,02253941 ! regulation of binding GO:0051098 60 57 2,000 3,704E-03 0,02361949 ! regulation of protein localization GO:0032880 58 57 2,000 3,704E-03 0,02353804 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 3,834E-03 0,02428425 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 3,834E-03 0,02420108 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 3,834E-03 0,02411848 ! myelination GO:0042552 17 17 1,000 3,834E-03 0,02403645 ! glucose transport GO:0015758 17 17 1,000 3,834E-03 0,02395497 ! tissue remodeling GO:0048771 17 17 1,000 3,834E-03 0,02387404 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 3,834E-03 0,02379365 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 3,834E-03 0,02371381 ! response to toxin GO:0009636 18 17 1,000 3,834E-03 0,0236345 ! cell recognition GO:0008037 18 17 1,000 3,834E-03 0,02355572 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 3,834E-03 0,02347746 ! pigmentation GO:0043473 17 17 1,000 3,834E-03 0,02339972 ! adult locomotory behavior GO:0008344 17 17 1,000 3,834E-03 0,02332249 ! dephosphorylation GO:0016311 60 59 2,000 4,084E-03 0,02475878 ! regulation of cell projection organization GO:0031344 19 18 1,000 4,299E-03 0,02597525 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 4,299E-03 0,02589037 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 4,299E-03 0,02580603 ! mononuclear cell proliferation GO:0032943 18 18 1,000 4,299E-03 0,02572225 GO:0070661|leukocyte proliferation, ! hexose transport GO:0008645 18 18 1,000 4,299E-03 0,025639 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 4,299E-03 0,0255563 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 4,299E-03 0,02547412 ! ensheathment of neurons GO:0007272 18 18 1,000 4,299E-03 0,02539248 GO:0008366|axon ensheathment, ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 4,299E-03 0,02531135 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 4,697E-03 0,02757088 GO:0060429|epithelium development, ! DNA damage checkpoint GO:0000077 19 19 1,000 4,788E-03 0,02801198 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 4,788E-03 0,02792333 ! regulation of pH GO:0006885 19 19 1,000 4,788E-03 0,02783525 ! feeding behavior GO:0007631 19 19 1,000 4,788E-03 0,02774771 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 4,788E-03 0,02766073 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 4,788E-03 0,02757429 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 4,788E-03 0,02748839 ! metanephros development GO:0001656 19 19 1,000 4,788E-03 0,02740302 ! cellular response to oxidative stress GO:0034599 19 19 1,000 4,788E-03 0,02731818 ! peripheral nervous system development GO:0007422 19 19 1,000 4,788E-03 0,02723387 ! regulation of protein stability GO:0031647 19 19 1,000 4,788E-03 0,02715007 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 4,788E-03 0,02706679 ! regulation of cell shape GO:0008360 21 19 1,000 4,788E-03 0,02698402 ! response to heat GO:0009408 19 19 1,000 4,788E-03 0,02690175 ! regulation of response to external stimulus GO:0032101 65 64 2,000 5,136E-03 0,02876945 ! regulation of muscle development GO:0048634 21 20 1,000 5,301E-03 0,02960659 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 5,301E-03 0,02951715 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 5,301E-03 0,02942824 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 5,301E-03 0,02933987 ! female gamete generation GO:0007292 20 20 1,000 5,301E-03 0,02925202 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 5,301E-03 0,0291647 ! striated muscle tissue development GO:0014706 69 67 2,000 5,838E-03 0,03202372 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 5,838E-03 0,03192869 ! mammary gland development GO:0030879 23 21 1,000 5,839E-03 0,03183775 ! DNA integrity checkpoint GO:0031570 21 21 1,000 5,839E-03 0,03174384 ! regulation of action potential in neuron GO:0019228 21 21 1,000 5,839E-03 0,03165047 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 5,839E-03 0,03155766 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 5,839E-03 0,03146538 ! regulation of cell size GO:0008361 68 68 2,000 6,085E-03 0,03269396 ! regionalization GO:0003002 70 69 2,000 6,337E-03 0,03395187 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 6,401E-03 0,03419198 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 6,401E-03 0,03409316 ! embryonic skeletal system development GO:0048706 22 22 1,000 6,401E-03 0,03399491 ! ovulation cycle process GO:0022602 22 22 1,000 6,401E-03 0,03389722 ! male sex differentiation GO:0046661 22 22 1,000 6,401E-03 0,0338001 ! wound healing GO:0042060 74 70 2,000 6,596E-03 0,03473225 ! muscle tissue development GO:0060537 72 70 2,000 6,596E-03 0,0346333 ! response to hydrogen peroxide GO:0042542 24 23 1,000 6,986E-03 0,03657643 ! response to estrogen stimulus GO:0043627 23 23 1,000 6,986E-03 0,03647281 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 6,986E-03 0,03636978 ! endocrine system development GO:0035270 23 23 1,000 6,986E-03 0,03626733 ! female gonad development GO:0008585 23 23 1,000 6,986E-03 0,03616546 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 6,986E-03 0,03606415 ! calcium-mediated signaling GO:0019722 23 23 1,000 6,986E-03 0,03596342 ! cell projection assembly GO:0030031 25 23 1,000 6,986E-03 0,03586324 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 7,132E-03 0,03651265 ! regulation of action potential GO:0001508 24 24 1,000 7,595E-03 0,03877197 ! glucose homeostasis GO:0042593 24 24 1,000 7,595E-03 0,03866487 GO:0033500|carbohydrate homeostasis, ! ovulation cycle GO:0042698 24 24 1,000 7,595E-03 0,03855836 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 7,595E-03 0,03845243 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 7,595E-03 0,03834708 ! glucan metabolic process GO:0044042 25 24 1,000 7,595E-03 0,0382423 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! response to oxidative stress GO:0006979 76 75 2,000 7,984E-03 0,04009377 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 8,226E-03 0,04119861 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 8,226E-03 0,04108696 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 8,226E-03 0,04097592 ! positive regulation of DNA binding GO:0043388 26 25 1,000 8,226E-03 0,04086547 ! heart morphogenesis GO:0003007 25 25 1,000 8,226E-03 0,04075562 ! negative regulation of immune system process GO:0002683 25 25 1,000 8,226E-03 0,04064635 ! positive regulation of binding GO:0051099 27 26 1,000 8,881E-03 0,04376375 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 8,881E-03 0,04364705 ! regulation of T cell differentiation GO:0045580 26 26 1,000 8,881E-03 0,04353096 ! double-strand break repair GO:0006302 27 26 1,000 8,881E-03 0,0434155 ! germ cell development GO:0007281 27 26 1,000 8,881E-03 0,04330064 ! pigment metabolic process GO:0042440 26 26 1,000 8,881E-03 0,04318639 ! synapse organization GO:0050808 26 26 1,000 8,881E-03 0,04307274 ! microtubule-based movement GO:0007018 82 78 2,000 8,894E-03 0,04302032 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 9,558E-03 0,04611484 ! energy reserve metabolic process GO:0006112 28 27 1,000 9,558E-03 0,04599443 ! learning or memory GO:0007611 28 27 1,000 9,558E-03 0,04587466 ! activation of caspase activity GO:0006919 27 27 1,000 9,558E-03 0,0457555 ! mesenchymal cell development GO:0014031 29 27 1,000 9,558E-03 0,04563696 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! lymphocyte activation GO:0046649 82 81 2,000 9,862E-03 0,04696408 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,01025789 0,04872498 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 1,000 0,01025789 0,04859972 ! carbohydrate transport GO:0008643 28 28 1,000 0,01025789 0,04847511 ! histone modification GO:0016570 28 28 1,000 0,01025789 0,04835113 ! developmental growth GO:0048589 28 28 1,000 0,01025789 0,04822778 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01025789 0,04810507 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01097962 0,051359 ! viral reproductive process GO:0022415 29 29 1,000 0,01097962 0,05122898 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01097962 0,05109961 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 0,01097962 0,0509709 ! adult behavior GO:0030534 30 29 1,000 0,01097962 0,05084283 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01097962 0,05071541 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01172321 0,05401467 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01172321 0,05387997 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01172321 0,05374594 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,01172321 0,05361258 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01172321 0,05347987 ! regulation of ossification GO:0030278 30 30 1,000 0,01172321 0,05334782 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01172321 0,05321642 ! vesicle organization GO:0016050 30 30 1,000 0,01172321 0,05308567 ! regulation of translational initiation GO:0006446 31 31 1,000 0,01248839 0,056412 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01248839 0,05627407 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,01248839 0,05613682 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01248839 0,05600023 ! membrane fusion GO:0006944 31 31 1,000 0,01248839 0,05586431 ! brain development GO:0007420 91 90 2,000 0,01312516 0,05857063 ! muscle fiber development GO:0048747 32 32 1,000 0,01327492 0,05909582 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01327492 0,05895342 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01327492 0,05881171 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01327492 0,05867067 ! kidney development GO:0001822 32 32 1,000 0,01327492 0,05853031 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01327492 0,05839062 ! tissue morphogenesis GO:0048729 94 93 2,000 0,01433464 0,06290175 ! response to metal ion GO:0010038 34 34 1,000 0,01491104 0,06527566 ! ear development GO:0043583 34 34 1,000 0,01491104 0,06512098 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,01491104 0,06496703 ! secondary metabolic process GO:0019748 34 34 1,000 0,01491104 0,0648138 ! viral reproduction GO:0016032 34 34 1,000 0,01491104 0,0646613 ! regulation of cell growth GO:0001558 97 96 2,000 0,01560576 0,06751504 ! mesoderm development GO:0007498 35 35 1,000 0,01576015 0,06802333 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,01576015 0,0678644 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01576015 0,06770621 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,01576015 0,06754875 ! blood circulation GO:0008015 99 98 2,000 0,01648761 0,0705027 GO:0003013|circulatory system process, ! response to inorganic substance GO:0010035 36 36 1,000 0,01662964 0,07094543 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,01662964 0,07078159 ! regulation of mitosis GO:0007088 37 36 1,000 0,01662964 0,0706185 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01662964 0,07045615 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,01662964 0,07029456 ! gonad development GO:0008406 36 36 1,000 0,01662964 0,0701337 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01662964 0,06997358 ! coagulation GO:0050817 39 36 1,000 0,01662964 0,06981418 GO:0007596|blood coagulation, ! anti-apoptosis GO:0006916 100 99 2,000 0,0169389 0,07095091 ! muscle organ development GO:0007517 102 100 2,000 0,01739713 0,072705 ! hemopoiesis GO:0030097 104 100 2,000 0,01739713 0,07254051 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,01751927 0,07288489 GO:0090046|regulation of transcription regulator activity, ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,01751927 0,07272074 ! adaptive immune response GO:0002250 37 37 1,000 0,01751927 0,07255732 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! urogenital system development GO:0001655 38 38 1,000 0,01842879 0,07615306 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,01842879 0,0759827 ! hemostasis GO:0007599 42 39 1,000 0,01935799 0,07963565 ! activation of MAPK activity GO:0000187 39 39 1,000 0,01935799 0,07945828 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01935799 0,07928171 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,02030661 0,08298246 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,02127445 0,08674514 ! regulation of caspase activity GO:0043281 41 41 1,000 0,02127445 0,08655365 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,02226125 0,09036891 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,02226125 0,09017029 ! response to protein stimulus GO:0051789 42 42 1,000 0,02226125 0,08997255 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,02226125 0,08977568 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,02226125 0,08957966 ! reproductive structure development GO:0048608 43 43 1,000 0,0232668 0,09342204 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,0232668 0,09321895 ! humoral immune response GO:0006959 44 44 1,000 0,02429087 0,0971108 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,02429087 0,09690061 ! protein import into nucleus GO:0006606 44 44 1,000 0,02429087 0,09669132 ! regulation of DNA binding GO:0051101 47 45 1,000 0,02533324 0,1006232 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,02533324 0,10040681 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,02533324 0,10019134 ! nuclear import GO:0051170 45 45 1,000 0,02533324 0,0999768 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,02639369 0,10393924 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,02639369 0,10371762 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,02639369 0,10349695 ! rRNA transcription GO:0009303 5 5 0,000 0,02732075 0,10690477 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02732075 0,10667827 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02732075 0,10645274 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02732075 0,10622815 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02732075 0,10600452 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02732075 0,10578182 ! reproductive cellular process GO:0048610 5 5 0,000 0,02732075 0,10556005 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02732075 0,10533921 ! prostate gland development GO:0030850 5 5 0,000 0,02732075 0,1051193 ! water transport GO:0006833 5 5 0,000 0,02732075 0,1049003 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02732075 0,10468221 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02732075 0,10446503 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02732075 0,10424875 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02732075 0,10403336 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02732075 0,10381885 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02732075 0,10360524 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02732075 0,10339249 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02732075 0,10318062 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02732075 0,10296962 ! filopodium assembly GO:0046847 7 5 0,000 0,02732075 0,10275948 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02732075 0,10255019 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02732075 0,10234176 ! GTP metabolic process GO:0046039 5 5 0,000 0,02732075 0,10213417 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02732075 0,10192742 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02732075 0,1017215 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02732075 0,10151642 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02732075 0,10131216 ! social behavior GO:0035176 5 5 0,000 0,02732075 0,10110872 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02732075 0,1009061 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02732075 0,10070429 ! memory GO:0007613 5 5 0,000 0,02732075 0,10050328 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02732075 0,10030308 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02732075 0,10010367 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02732075 0,09990505 ! response to lipid GO:0033993 5 5 0,000 0,02732075 0,09970722 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02732075 0,09951017 ! hippocampus development GO:0021766 6 5 0,000 0,02732075 0,09931389 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02732075 0,0991184 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02732075 0,09892366 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02732075 0,0987297 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02732075 0,09853649 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02732075 0,09834403 ! heart looping GO:0001947 5 5 0,000 0,02732075 0,09815233 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02732075 0,09796137 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02732075 0,09777115 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02732075 0,09758168 ! pH reduction GO:0045851 5 5 0,000 0,02732075 0,09739293 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02732075 0,09720491 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02732075 0,09701762 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02732075 0,09683105 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02732075 0,09664519 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02732075 0,09646005 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02732075 0,09627561 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02732075 0,09609188 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02732075 0,09590885 ! adrenal gland development GO:0030325 5 5 0,000 0,02732075 0,09572651 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02732075 0,09554487 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02732075 0,09536391 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02732075 0,09518364 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02732075 0,09500405 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02732075 0,09482513 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02732075 0,09464689 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02732075 0,09446931 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02732075 0,09429241 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02732075 0,09411616 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02732075 0,09394057 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02732075 0,09376563 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02732075 0,09359135 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02732075 0,09341771 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02732075 0,09324471 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02732075 0,09307236 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02732075 0,09290064 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02732075 0,09272955 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02732075 0,09255909 ! response to ATP GO:0033198 5 5 0,000 0,02732075 0,09238926 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02732075 0,09222005 ! regulation of appetite GO:0032098 5 5 0,000 0,02732075 0,09205145 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02732075 0,09188348 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02732075 0,09171611 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02732075 0,09154935 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02732075 0,0913832 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02732075 0,09121765 ! receptor clustering GO:0043113 5 5 0,000 0,02732075 0,0910527 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02732075 0,09088835 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02732075 0,09072458 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02732075 0,09056141 ! retinol metabolic process GO:0042572 5 5 0,000 0,02732075 0,09039882 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02732075 0,09023682 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02732075 0,09007539 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02732075 0,08991454 ! parturition GO:0007567 5 5 0,000 0,02732075 0,08975427 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02732075 0,08959456 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02732075 0,08943543 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02732075 0,08927685 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02732075 0,08911884 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02732075 0,08896139 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02732075 0,08880449 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02732075 0,08864814 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02732075 0,08849235 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02732075 0,0883371 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02732075 0,08818239 ! interaction with symbiont GO:0051702 5 5 0,000 0,02732075 0,08802822 ! cellular extravasation GO:0045123 5 5 0,000 0,02732075 0,0878746 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02732075 0,08772151 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02732075 0,08756895 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02732075 0,08741692 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02732075 0,08726542 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02732075 0,08711444 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02732075 0,08696398 ! response to amine stimulus GO:0014075 5 5 0,000 0,02732075 0,08681404 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02732075 0,08666462 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02732075 0,08651571 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02732075 0,08636732 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02732075 0,08621943 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02732075 0,08607204 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02732075 0,08592516 ! decidualization GO:0046697 5 5 0,000 0,02732075 0,08577878 ! hair follicle maturation GO:0048820 5 5 0,000 0,02732075 0,0856329 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02732075 0,08548751 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02732075 0,08534262 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02732075 0,08519821 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02732075 0,0850543 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02732075 0,08491087 ! postreplication repair GO:0006301 5 5 0,000 0,02732075 0,08476792 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02732075 0,08462545 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,02732075 0,08448346 ! DNA methylation GO:0006306 5 5 0,000 0,02732075 0,08434195 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02732075 0,08420091 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02732075 0,08406034 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02732075 0,08392024 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02732075 0,08378061 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02732075 0,08364144 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02732075 0,08350273 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02732075 0,08336448 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02732075 0,08322669 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02732075 0,08308935 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02732075 0,08295246 ! sterol catabolic process GO:0016127 5 5 0,000 0,02732075 0,08281603 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02732075 0,08268004 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02732075 0,0825445 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02732075 0,0824094 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02732075 0,08227475 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02732075 0,08214053 ! zymogen activation GO:0031638 5 5 0,000 0,02732075 0,08200675 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02732075 0,08187341 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02732075 0,08174049 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02732075 0,08160801 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02732075 0,08147596 ! nucleosome positioning GO:0016584 5 5 0,000 0,02732075 0,08134434 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02732075 0,08121314 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02732075 0,08108236 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02732075 0,080952 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02732075 0,08082206 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02732075 0,08069254 ! NADPH regeneration GO:0006740 5 5 0,000 0,02732075 0,08056343 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02732075 0,08043474 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02732075 0,08030645 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02732075 0,08017857 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02732075 0,0800511 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02732075 0,07992404 ! sarcomere organization GO:0045214 5 5 0,000 0,02732075 0,07979738 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02732075 0,07967111 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02732075 0,07954525 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02732075 0,07941979 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02732075 0,07929472 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02732075 0,07917004 ! male genitalia development GO:0030539 5 5 0,000 0,02732075 0,07904575 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02732075 0,07892186 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02732075 0,07879835 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02732075 0,07867523 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02732075 0,07855249 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02732075 0,07843013 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02732075 0,07830816 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02732075 0,07818656 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02732075 0,07806534 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02732075 0,0779445 ! ATP catabolic process GO:0006200 5 5 0,000 0,02732075 0,07782403 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02732075 0,07770393 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02732075 0,0775842 ! blastocyst formation GO:0001825 5 5 0,000 0,02732075 0,07746484 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02732075 0,07734584 ! embryonic gut development GO:0048566 5 5 0,000 0,02732075 0,07722722 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02732075 0,07710895 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02732075 0,07699105 ! activation of innate immune response GO:0002218 5 5 0,000 0,02732075 0,0768735 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,02732075 0,07675632 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02732075 0,07663949 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02732075 0,07652302 ! muscle adaptation GO:0043500 5 5 0,000 0,02732075 0,0764069 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02732075 0,07629113 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02732075 0,07617571 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02732075 0,07606064 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02732075 0,07594592 ! defense response to fungus GO:0050832 5 5 0,000 0,02732075 0,07583154 ! lysogeny GO:0030069 5 5 0,000 0,02732075 0,07571751 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02732075 0,07560382 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02732075 0,07549047 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02732075 0,07537746 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02732075 0,07526479 ! mitochondrion localization GO:0051646 5 5 0,000 0,02732075 0,07515245 ! nucleus localization GO:0051647 5 5 0,000 0,02732075 0,07504045 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02732075 0,07492879 ! sex differentiation GO:0007548 47 47 1,000 0,02747199 0,07523161 ! rhythmic process GO:0048511 47 47 1,000 0,02747199 0,07511999 ! regulation of catabolic process GO:0009894 48 47 1,000 0,02747199 0,0750087 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,02856792 0,07788563 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,02856792 0,07777058 ! protein localization in nucleus GO:0034504 48 48 1,000 0,02856792 0,07765588 ! ossification GO:0001503 50 49 1,000 0,02968128 0,08056347 GO:0060348|bone development, ! regulation of ligase activity GO:0051340 50 49 1,000 0,02968128 0,080445 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,03081184 0,08338653 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,0319594 0,08636535 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03269701 0,08822928 ! axon extension GO:0048675 7 6 0,000 0,03269701 0,08810029 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03269701 0,08797168 ! tRNA modification GO:0006400 6 6 0,000 0,03269701 0,08784344 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03269701 0,08771557 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03269701 0,08758808 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03269701 0,08746096 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03269701 0,0873342 ! regulation of S phase GO:0033261 6 6 0,000 0,03269701 0,08720781 ! myotube differentiation GO:0014902 6 6 0,000 0,03269701 0,08708179 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03269701 0,08695613 ! bone remodeling GO:0046849 6 6 0,000 0,03269701 0,08683083 ! N-glycan processing GO:0006491 6 6 0,000 0,03269701 0,0867059 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,03269701 0,08658132 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03269701 0,0864571 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03269701 0,08633324 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03269701 0,08620973 ! RNA methylation GO:0001510 6 6 0,000 0,03269701 0,08608657 ! cartilage condensation GO:0001502 7 6 0,000 0,03269701 0,08596376 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03269701 0,08584131 ! succinate metabolic process GO:0006105 7 6 0,000 0,03269701 0,0857192 ! artery development GO:0060840 6 6 0,000 0,03269701 0,08559744 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03269701 0,08547603 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03269701 0,08535496 ! androgen metabolic process GO:0008209 6 6 0,000 0,03269701 0,08523423 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03269701 0,08511384 ! limbic system development GO:0021761 7 6 0,000 0,03269701 0,08499379 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03269701 0,08487408 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,03269701 0,08475471 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03269701 0,08463567 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03269701 0,08451697 ! pathogenesis GO:0009405 6 6 0,000 0,03269701 0,0843986 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03269701 0,08428056 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03269701 0,08416285 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03269701 0,08404546 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03269701 0,08392841 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03269701 0,08381168 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03269701 0,08369528 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03269701 0,08357919 ! arginine metabolic process GO:0006525 6 6 0,000 0,03269701 0,08346343 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03269701 0,08334799 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03269701 0,08323287 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03269701 0,08311807 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03269701 0,08300358 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03269701 0,08288941 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03269701 0,08277555 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03269701 0,082662 ! V(D)J recombination GO:0033151 6 6 0,000 0,03269701 0,08254876 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03269701 0,08243584 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03269701 0,08232322 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03269701 0,08221091 ! regulation of heart rate GO:0002027 6 6 0,000 0,03269701 0,08209891 ! lipid digestion GO:0044241 6 6 0,000 0,03269701 0,08198721 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03269701 0,08187581 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03269701 0,08176472 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03269701 0,08165393 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03269701 0,08154343 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03269701 0,08143324 ! ruffle organization GO:0031529 6 6 0,000 0,03269701 0,08132334 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03269701 0,08121374 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03269701 0,08110444 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03269701 0,08099543 ! L-amino acid transport GO:0015807 6 6 0,000 0,03269701 0,08088671 ! bone mineralization GO:0030282 6 6 0,000 0,03269701 0,08077828 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03269701 0,08067014 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03269701 0,0805623 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03269701 0,08045474 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03269701 0,08034746 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03269701 0,08024048 ! regulation of organ growth GO:0046620 6 6 0,000 0,03269701 0,08013377 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03269701 0,08002735 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03269701 0,07992122 ! response to dsRNA GO:0043331 6 6 0,000 0,03269701 0,07981536 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03269701 0,07970979 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03269701 0,07960449 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03269701 0,07949947 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03269701 0,07939473 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03269701 0,07929026 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03269701 0,07918607 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03269701 0,07908215 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03269701 0,0789785 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03269701 0,07887513 ! erythrocyte development GO:0048821 6 6 0,000 0,03269701 0,07877202 ! renal water homeostasis GO:0003091 6 6 0,000 0,03269701 0,07866919 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03269701 0,07856662 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03269701 0,07846432 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03269701 0,07836229 ! ribosome assembly GO:0042255 6 6 0,000 0,03269701 0,07826052 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03269701 0,07815901 ! diencephalon development GO:0021536 6 6 0,000 0,03269701 0,07805777 ! fucose catabolic process GO:0019317 6 6 0,000 0,03269701 0,07795679 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03269701 0,07785607 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03269701 0,07775561 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03269701 0,07765541 ! regulation of cell division GO:0051302 6 6 0,000 0,03269701 0,07755547 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03269701 0,07745578 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03269701 0,07735635 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03269701 0,07725718 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03269701 0,07715826 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03269701 0,07705959 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03269701 0,07696117 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03269701 0,07686301 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03269701 0,07676509 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03269701 0,07666743 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03269701 0,07657001 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03269701 0,07647284 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03269701 0,07637592 ! lymph node development GO:0048535 6 6 0,000 0,03269701 0,07627924 ! organic cation transport GO:0015695 6 6 0,000 0,03269701 0,0761828 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03269701 0,07608661 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03269701 0,07599067 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03269701 0,07589496 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03269701 0,07579949 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03269701 0,07570427 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03269701 0,07560928 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03269701 0,07551453 ! alditol metabolic process GO:0019400 6 6 0,000 0,03269701 0,07542002 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03269701 0,07532575 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03269701 0,07523171 ! maternal placenta development GO:0001893 6 6 0,000 0,03269701 0,0751379 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03269701 0,07504433 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,03312373 0,07592915 ! regulation of T cell activation GO:0050863 53 53 1,000 0,03430464 0,07853844 ! regulation of protein transport GO:0051223 53 53 1,000 0,03430464 0,078441 GO:0070201|regulation of establishment of protein localization, ! response to virus GO:0009615 54 54 1,000 0,0355019 0,08107808 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,03671533 0,08374548 ! in utero embryonic development GO:0001701 55 55 1,000 0,03671533 0,08364196 ! extracellular structure organization GO:0043062 56 56 1,000 0,0379447 0,08633591 ! respiratory burst GO:0045730 7 7 0,000 0,03804434 0,08645588 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,03804434 0,08634941 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03804434 0,0862432 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03804434 0,08613725 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03804434 0,08603156 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03804434 0,08592613 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,03804434 0,08582095 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03804434 0,08571604 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03804434 0,08561138 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03804434 0,08550697 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,03804434 0,08540282 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03804434 0,08529893 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,03804434 0,08519528 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03804434 0,08509189 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,03804434 0,08498875 ! axis specification GO:0009798 7 7 0,000 0,03804434 0,08488586 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03804434 0,08478321 ! visual behavior GO:0007632 7 7 0,000 0,03804434 0,08468082 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03804434 0,08457867 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03804434 0,08447677 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03804434 0,08437511 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03804434 0,0842737 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03804434 0,08417253 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03804434 0,08407161 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03804434 0,08397092 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03804434 0,08387048 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03804434 0,08377027 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03804434 0,08367031 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03804434 0,08357058 ! protein targeting to ER GO:0045047 8 7 0,000 0,03804434 0,08347109 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03804434 0,08337184 ! endoderm development GO:0007492 7 7 0,000 0,03804434 0,08327282 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03804434 0,08317404 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03804434 0,0830755 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,03804434 0,08297718 ! response to hexose stimulus GO:0009746 7 7 0,000 0,03804434 0,0828791 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03804434 0,08278125 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03804434 0,08268363 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,03804434 0,08258624 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03804434 0,08248908 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03804434 0,08239215 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03804434 0,08229544 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03804434 0,08219897 ! UV protection GO:0009650 7 7 0,000 0,03804434 0,08210272 ! DNA integration GO:0015074 7 7 0,000 0,03804434 0,08200669 ! myofibril assembly GO:0030239 7 7 0,000 0,03804434 0,08191089 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03804434 0,08181531 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03804434 0,08171995 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03804434 0,08162482 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03804434 0,08152991 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03804434 0,08143521 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03804434 0,08134074 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03804434 0,08124649 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03804434 0,08115245 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03804434 0,08105863 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03804434 0,08096503 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03804434 0,08087165 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03804434 0,08077848 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03804434 0,08068552 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03804434 0,08059278 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03804434 0,08050025 ! induction of an organ GO:0001759 7 7 0,000 0,03804434 0,08040793 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03804434 0,08031583 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03804434 0,08022393 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03804434 0,08013225 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03804434 0,08004077 ! platelet activation GO:0030168 8 7 0,000 0,03804434 0,07994951 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03804434 0,07985845 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03804434 0,0797676 ! natural killer cell activation GO:0030101 7 7 0,000 0,03804434 0,07967695 ! NADP metabolic process GO:0006739 7 7 0,000 0,03804434 0,07958651 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03804434 0,07949628 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03804434 0,07940625 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03804434 0,07931642 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,03804434 0,0792268 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03804434 0,07913738 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03804434 0,07904816 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03804434 0,07895914 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03804434 0,07887032 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03804434 0,07878171 ! cell-cell recognition GO:0009988 8 7 0,000 0,03804434 0,07869329 ! hormone catabolic process GO:0042447 7 7 0,000 0,03804434 0,07860507 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03804434 0,07851704 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03804434 0,07842922 ! oxygen transport GO:0015671 7 7 0,000 0,03804434 0,07834159 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03804434 0,07825415 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03804434 0,07816691 ! cell killing GO:0001906 7 7 0,000 0,03804434 0,07807986 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03804434 0,07799301 ! adult feeding behavior GO:0008343 7 7 0,000 0,03804434 0,07790635 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03804434 0,07781989 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03804434 0,07773361 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03804434 0,07764753 ! response to cold GO:0009409 7 7 0,000 0,03804434 0,07756164 ! protein localization in organelle GO:0033365 59 59 1,000 0,04172652 0,08497456 ! immune effector process GO:0002252 59 59 1,000 0,04172652 0,08488077 ! protein polymerization GO:0051258 65 60 1,000 0,04301769 0,08741081 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04336288 0,08801518 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04336288 0,08791836 ! positive regulation of translation GO:0045727 8 8 0,000 0,04336288 0,08782174 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04336288 0,08772534 ! superoxide anion generation GO:0042554 8 8 0,000 0,04336288 0,08762915 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04336288 0,08753317 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04336288 0,0874374 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04336288 0,08734184 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04336288 0,08724649 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04336288 0,08715135 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04336288 0,08705641 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04336288 0,08696168 ! zinc ion transport GO:0006829 8 8 0,000 0,04336288 0,08686716 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04336288 0,08677284 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04336288 0,08667873 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04336288 0,08658482 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04336288 0,08649111 ! lipid localization GO:0010876 8 8 0,000 0,04336288 0,08639761 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04336288 0,0863043 ! response to cAMP GO:0051591 8 8 0,000 0,04336288 0,0862112 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04336288 0,0861183 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04336288 0,0860256 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04336288 0,0859331 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04336288 0,0858408 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04336288 0,0857487 GO:0032107|regulation of response to nutrient levels, ! sensory perception of taste GO:0050909 8 8 0,000 0,04336288 0,08565679 ! organelle fusion GO:0048284 8 8 0,000 0,04336288 0,08556508 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04336288 0,08547357 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04336288 0,08538225 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04336288 0,08529113 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04336288 0,0852002 ! sperm motility GO:0030317 8 8 0,000 0,04336288 0,08510946 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04336288 0,08501892 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04336288 0,08492857 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04336288 0,08483841 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04336288 0,08474845 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04336288 0,08465867 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04336288 0,08456908 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04336288 0,08447969 ! Golgi organization GO:0007030 8 8 0,000 0,04336288 0,08439048 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04336288 0,08430146 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04336288 0,08421263 ! fructose metabolic process GO:0006000 8 8 0,000 0,04336288 0,08412398 ! mannose metabolic process GO:0006013 9 8 0,000 0,04336288 0,08403553 ! NAD metabolic process GO:0019674 8 8 0,000 0,04336288 0,08394725 ! response to fungus GO:0009620 8 8 0,000 0,04336288 0,08385917 ! stem cell differentiation GO:0048863 8 8 0,000 0,04336288 0,08377126 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,04336288 0,08368354 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04336288 0,08359601 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04336288 0,08350866 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04336288 0,08342149 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04336288 0,0833345 ! vasoconstriction GO:0042310 8 8 0,000 0,04336288 0,08324769 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04336288 0,08316107 ! muscle cell development GO:0055001 8 8 0,000 0,04336288 0,08307462 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04336288 0,08298835 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04336288 0,08290227 ! sensory perception of pain GO:0019233 8 8 0,000 0,04336288 0,08281636 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04336288 0,08273063 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04336288 0,08264507 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04336288 0,0825597 ! chromatin silencing GO:0006342 8 8 0,000 0,04336288 0,08247449 ! tissue regeneration GO:0042246 8 8 0,000 0,04336288 0,08238947 ! salivary gland development GO:0007431 8 8 0,000 0,04336288 0,08230462 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04336288 0,08221994 ! water homeostasis GO:0030104 8 8 0,000 0,04336288 0,08213544 ! cofactor transport GO:0051181 8 8 0,000 0,04336288 0,08205111 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04336288 0,08196696 ! acid secretion GO:0046717 8 8 0,000 0,04336288 0,08188298 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04336288 0,08179917 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04336288 0,08171553 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04336288 0,08163206 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04336288 0,08154876 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04336288 0,08146563 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04336288 0,08138267 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04336288 0,08129988 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04336288 0,08121726 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04336288 0,08113481 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04336288 0,08105252 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04336288 0,0809704 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04336288 0,08088845 ! developmental induction GO:0031128 8 8 0,000 0,04336288 0,08080666 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04336288 0,08072504 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04336288 0,08064358 ! actin filament polymerization GO:0030041 9 8 0,000 0,04336288 0,08056228 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,04336288 0,08048115 ! peptide hormone processing GO:0016486 8 8 0,000 0,04336288 0,08040019 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04336288 0,08031938 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04336288 0,08023874 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,04432382 0,0819346 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,04432382 0,0818525 ! protein import GO:0017038 62 62 1,000 0,0456447 0,08420738 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,0456447 0,08412318 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,04698014 0,08649791 ! lactation GO:0007595 10 9 0,000 0,04865278 0,0894881 ! embryonic pattern specification GO:0009880 10 9 0,000 0,04865278 0,08939888 ! positive regulation of cell size GO:0045793 9 9 0,000 0,04865278 0,08930984 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,04865278 0,08922097 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,04865278 0,08913228 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,04865278 0,08904377 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,04865278 0,08895543 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,04865278 0,08886727 ! viral genome replication GO:0019079 9 9 0,000 0,04865278 0,08877928 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,04865278 0,08869147 ! copper ion transport GO:0006825 9 9 0,000 0,04865278 0,08860383 ! lipid phosphorylation GO:0046834 9 9 0,000 0,04865278 0,08851636 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,04865278 0,08842907 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,04865278 0,08834195 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,04865278 0,088255 ! RNA polyadenylation GO:0043631 9 9 0,000 0,04865278 0,08816822 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,04865278 0,08808161 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,04865278 0,08799517 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,04865278 0,0879089 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,04865278 0,0878228 ! phospholipid efflux GO:0033700 9 9 0,000 0,04865278 0,08773686 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,04865278 0,0876511 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,04865278 0,0875655 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,04865278 0,08748007 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,04865278 0,08739481 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,04865278 0,08730971 ! methionine metabolic process GO:0006555 9 9 0,000 0,04865278 0,08722478 ! glutamine metabolic process GO:0006541 9 9 0,000 0,04865278 0,08714002 ! cerebral cortex development GO:0021987 9 9 0,000 0,04865278 0,08705541 ! response to osmotic stress GO:0006970 9 9 0,000 0,04865278 0,08697098 ! pigmentation during development GO:0048066 9 9 0,000 0,04865278 0,0868867 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,04865278 0,08680259 ! central nervous system neuron development GO:0021954 10 9 0,000 0,04865278 0,08671864 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,04865278 0,08663486 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,04865278 0,08655123 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,04865278 0,08646777 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,04865278 0,08638447 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,04865278 0,08630132 ! L-glutamate transport GO:0015813 9 9 0,000 0,04865278 0,08621834 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,04865278 0,08613552 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,04865278 0,08605286 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,04865278 0,08597035 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,04865278 0,085888 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,04865278 0,08580581 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,04865278 0,08572378 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,04865278 0,08564191 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,04865278 0,08556019 ! DNA replication initiation GO:0006270 9 9 0,000 0,04865278 0,08547862 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,04865278 0,08539721 GO:0006692|prostanoid metabolic process, ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,04865278 0,08531596 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,04865278 0,08523486 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,04865278 0,08515392 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,04865278 0,08507313 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,04865278 0,08499249 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,04865278 0,084912 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,04865278 0,08483167 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,04865278 0,08475149 ! collagen catabolic process GO:0030574 9 9 0,000 0,04865278 0,08467146 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,04865278 0,08459158 ! purine base metabolic process GO:0006144 9 9 0,000 0,04865278 0,08451185 ! gas transport GO:0015669 9 9 0,000 0,04865278 0,08443227 ! cholesterol efflux GO:0033344 9 9 0,000 0,04865278 0,08435285 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,04865278 0,08427357 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,04865278 0,08419444 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,04865278 0,08411546 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,04865278 0,08403662 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,04865278 0,08395794 ! actin filament-based movement GO:0030048 9 9 0,000 0,04865278 0,0838794 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,04865278 0,08380101 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,05107196 0,08788574 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,0539142 0,09269017 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,0539142 0,09260379 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,0539142 0,09251757 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,0539142 0,0924315 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,0539142 0,0923456 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,0539142 0,09225986 ! neuron maturation GO:0042551 10 10 0,000 0,0539142 0,09217427 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,0539142 0,09208885 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,0539142 0,09200358 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,0539142 0,09191847 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,0539142 0,09183352 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,0539142 0,09174872 ! hormone secretion GO:0046879 10 10 0,000 0,0539142 0,09166408 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,0539142 0,0915796 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,0539142 0,09149527 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,0539142 0,0914111 ! inositol metabolic process GO:0006020 10 10 0,000 0,0539142 0,09132708 ! cAMP metabolic process GO:0046058 10 10 0,000 0,0539142 0,09124322 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,0539142 0,09115951 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,0539142 0,09107595 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,0539142 0,09099255 ! glial cell development GO:0021782 10 10 0,000 0,0539142 0,0909093 ! phototransduction GO:0007602 11 10 0,000 0,0539142 0,0908262 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,0539142 0,09074326 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,0539142 0,09066046 ! fat cell differentiation GO:0045444 10 10 0,000 0,0539142 0,09057782 ! myoblast differentiation GO:0045445 10 10 0,000 0,0539142 0,09049532 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,0539142 0,09041298 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,0539142 0,09033079 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,0539142 0,09024874 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,0539142 0,09016685 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,0539142 0,0900851 ! protein polyubiquitination GO:0000209 10 10 0,000 0,0539142 0,0900035 ! glutamate metabolic process GO:0006536 11 10 0,000 0,0539142 0,08992205 ! plasma membrane organization GO:0007009 10 10 0,000 0,0539142 0,08984075 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,0539142 0,08975959 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,0539142 0,08967858 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,0539142 0,08959772 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,0539142 0,089517 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,0539142 0,08943642 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,0539142 0,089356 ! exocrine system development GO:0035272 10 10 0,000 0,0539142 0,08927571 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,0539142 0,08919557 ! embryo implantation GO:0007566 11 10 0,000 0,0539142 0,08911558 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,0539142 0,08903572 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,0539142 0,08895601 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,0539142 0,08887645 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,0539142 0,08879702 ! protein export from nucleus GO:0006611 10 10 0,000 0,0539142 0,08871774 ! negative regulation of immune response GO:0050777 10 10 0,000 0,0539142 0,0886386 ! cytolysis GO:0019835 10 10 0,000 0,0539142 0,0885596 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,0539142 0,08848074 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,0539142 0,08840202 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,0539142 0,08832344 ! histone deacetylation GO:0016575 10 10 0,000 0,0539142 0,088245 ! mRNA splice site selection GO:0006376 11 10 0,000 0,0539142 0,0881667 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,0539142 0,08808853 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,0539142 0,08801051 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,0539142 0,08793263 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,0539142 0,08785488 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,0539142 0,08777727 ! regulation of epidermis development GO:0045682 10 10 0,000 0,0539142 0,08769979 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,0539142 0,08762246 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,0539142 0,08754526 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,0539142 0,08746819 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,0539142 0,08739126 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,0539142 0,08731447 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,0539142 0,08723781 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,0539142 0,08716129 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0539142 0,0870849 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,0539142 0,08700864 ! protein stabilization GO:0050821 10 10 0,000 0,0539142 0,08693252 ! regulation of translation GO:0006417 69 69 1,000 0,05528806 0,08906984 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,05528806 0,08899205 ! positive regulation of transport GO:0051050 71 70 1,000 0,05672018 0,09121754 ! growth GO:0040007 70 70 1,000 0,05672018 0,09113801 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,05816538 0,09337874 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 1,000 0,05816538 0,09329747 ! protein secretion GO:0009306 11 11 0,000 0,05914728 0,09478994 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,05914728 0,09470759 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,05914728 0,09462538 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,05914728 0,09454331 ! negative regulation of defense response GO:0031348 11 11 0,000 0,05914728 0,09446138 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,05914728 0,0943796 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,05914728 0,09429795 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,05914728 0,09421645 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,05914728 0,09413509 ! skin development GO:0043588 11 11 0,000 0,05914728 0,09405387 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,05914728 0,09397279 ! endothelial cell migration GO:0043542 11 11 0,000 0,05914728 0,09389185 ! peroxisomal transport GO:0043574 11 11 0,000 0,05914728 0,09381104 ! protein amino acid methylation GO:0006479 11 11 0,000 0,05914728 0,09373038 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,05914728 0,09364986 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,05914728 0,09356947 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! T cell proliferation GO:0042098 11 11 0,000 0,05914728 0,09348922 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,05914728 0,09340911 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,05914728 0,09332914 ! spinal cord development GO:0021510 11 11 0,000 0,05914728 0,0932493 ! smooth muscle contraction GO:0006939 11 11 0,000 0,05914728 0,0931696 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,05914728 0,09309004 ! digestive system process GO:0022600 11 11 0,000 0,05914728 0,09301061 ! mitotic spindle organization GO:0007052 11 11 0,000 0,05914728 0,09293132 ! fucose metabolic process GO:0006004 11 11 0,000 0,05914728 0,09285216 ! membrane budding GO:0006900 11 11 0,000 0,05914728 0,09277313 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,05914728 0,09269425 ! monoamine transport GO:0015844 11 11 0,000 0,05914728 0,09261549 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,05914728 0,09253687 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,05914728 0,09245838 ! body fluid secretion GO:0007589 11 11 0,000 0,05914728 0,09238003 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,05914728 0,09230181 ! intermediate filament-based process GO:0045103 11 11 0,000 0,05914728 0,09222372 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,05914728 0,09214576 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,05914728 0,09206793 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,05914728 0,09199024 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,05914728 0,09191268 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,05914728 0,09183524 ! vitamin transport GO:0051180 11 11 0,000 0,05914728 0,09175794 ! muscle maintenance GO:0046716 12 11 0,000 0,05914728 0,09168077 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,05914728 0,09160373 ! steroid catabolic process GO:0006706 11 11 0,000 0,05914728 0,09152681 ! endocrine process GO:0050886 11 11 0,000 0,05914728 0,09145003 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,05914728 0,09137337 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,05914728 0,09129685 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,05914728 0,09122045 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,05914728 0,09114417 ! sensory organ development GO:0007423 72 72 1,000 0,05962347 0,09180122 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,06435217 0,09899921 ! translational initiation GO:0006413 12 12 0,000 0,06435217 0,09891664 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,06435217 0,09883421 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06435217 0,09875191 ! initiation of viral infection GO:0019059 12 12 0,000 0,06435217 0,09866976 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,06435217 0,09858774 ! iron ion transport GO:0006826 13 12 0,000 0,06435217 0,09850585 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06435217 0,09842411 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06435217 0,0983425 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06435217 0,09826102 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06435217 0,09817968 ! collagen metabolic process GO:0032963 12 12 0,000 0,06435217 0,09809847 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06435217 0,0980174 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06435217 0,09793646 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06435217 0,09785565 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06435217 0,09777498 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06435217 0,09769444 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06435217 0,09761403 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,06435217 0,09753376 ! actomyosin structure organization GO:0031032 12 12 0,000 0,06435217 0,09745361 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,06435217 0,0973736 ! retinoid metabolic process GO:0001523 12 12 0,000 0,06435217 0,09729372 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06435217 0,09721397 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06435217 0,09713436 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06435217 0,09705487 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06435217 0,09697551 ! acute-phase response GO:0006953 12 12 0,000 0,06435217 0,09689628 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06435217 0,09681718 ! vacuolar transport GO:0007034 12 12 0,000 0,06435217 0,09673821 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06435217 0,09665937 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06435217 0,09658066 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06435217 0,09650207 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06435217 0,09642362 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,06435217 0,09634529 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,06435217 0,09626709 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06435217 0,09618901 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06435217 0,09611106 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06435217 0,09603324 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,06435217 0,09595554 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06435217 0,09587797 ! pallium development GO:0021543 13 12 0,000 0,06435217 0,09580052 ! cell fate determination GO:0001709 12 12 0,000 0,06435217 0,0957232 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,06435217 0,09564601 ! G1 phase GO:0051318 13 12 0,000 0,06435217 0,09556894 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06435217 0,09549199 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06435217 0,09541516 ! detection of light stimulus GO:0009583 13 12 0,000 0,06435217 0,09533846 ! synaptogenesis GO:0007416 12 12 0,000 0,06435217 0,09526189 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06435217 0,09518543 ! hormone transport GO:0009914 12 12 0,000 0,06435217 0,0951091 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06435217 0,09503289 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06435217 0,0949568 ! spermatid differentiation GO:0048515 13 12 0,000 0,06435217 0,09488084 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06435217 0,094805 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06435217 0,09472927 ! neural tube closure GO:0001843 13 12 0,000 0,06435217 0,09465367 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,06435217 0,09457819 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,06435217 0,09450283 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,06558126 0,0962311 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,06710119 0,09838305 ! regulation of protein modification process GO:0031399 79 78 1,000 0,06863297 0,10054894 ! metal ion homeostasis GO:0055065 78 78 1,000 0,06863297 0,10046908 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,06952902 0,10169999 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,06952902 0,10161934 ! phenol metabolic process GO:0018958 13 13 0,000 0,06952902 0,10153882 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,06952902 0,10145842 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,06952902 0,10137815 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,06952902 0,10129801 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,06952902 0,101218 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,06952902 0,10113811 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,06952902 0,10105835 ! keratinization GO:0031424 13 13 0,000 0,06952902 0,10097871 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,06952902 0,1008992 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,06952902 0,10081982 ! regulation of innate immune response GO:0045088 13 13 0,000 0,06952902 0,10074056 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,06952902 0,10066142 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,06952902 0,10058241 ! autophagy GO:0006914 13 13 0,000 0,06952902 0,10050352 ! receptor metabolic process GO:0043112 14 13 0,000 0,06952902 0,10042475 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,06952902 0,10034611 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,06952902 0,1002676 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,06952902 0,1001892 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,06952902 0,10011093 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,06952902 0,10003278 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,06952902 0,09995475 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,06952902 0,09987684 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,06952902 0,09979906 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,06952902 0,09972139 ! vasodilation GO:0042311 14 13 0,000 0,06952902 0,09964385 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,06952902 0,09956642 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,06952902 0,09948912 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,06952902 0,09941194 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,06952902 0,09933487 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,06952902 0,09925793 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,06952902 0,0991811 ! immunoglobulin production GO:0002377 13 13 0,000 0,06952902 0,0991044 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,06952902 0,09902781 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,06952902 0,09895134 ! cell-cell junction organization GO:0045216 13 13 0,000 0,06952902 0,09887499 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,06952902 0,09879876 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,06952902 0,09872264 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,06952902 0,09864664 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,06952902 0,09857076 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,06952902 0,09849499 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,06952902 0,09841934 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,06952902 0,09834381 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,06952902 0,09826839 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,06952902 0,09819309 ! blastocyst development GO:0001824 13 13 0,000 0,06952902 0,09811791 ! telomere organization GO:0032200 13 13 0,000 0,06952902 0,09804284 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,06952902 0,09796788 ! regulation of amine transport GO:0051952 13 13 0,000 0,06952902 0,09789304 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,06952902 0,09781831 ! nuclear transport GO:0051169 79 79 1,000 0,07017644 0,09865383 GO:0006913|nucleocytoplasmic transport, ! neuron fate commitment GO:0048663 14 14 0,000 0,07467798 0,10490207 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,07467798 0,10482218 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,07467798 0,1047424 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,07467798 0,10466275 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,07467798 0,10458322 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,07467798 0,10450381 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,07467798 0,10442452 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,07467798 0,10434535 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,07467798 0,1042663 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,07467798 0,10418737 ! vesicle docking GO:0048278 14 14 0,000 0,07467798 0,10410856 ! superoxide metabolic process GO:0006801 15 14 0,000 0,07467798 0,10402987 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,07467798 0,1039513 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,07467798 0,10387284 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,07467798 0,10379451 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,07467798 0,10371629 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,07467798 0,10363819 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,07467798 0,10356021 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 14 14 0,000 0,07467798 0,10348234 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,07467798 0,1034046 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,07467798 0,10332696 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,07467798 0,10324945 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,07467798 0,10317205 ! primary neural tube formation GO:0014020 15 14 0,000 0,07467798 0,10309477 ! peptide cross-linking GO:0018149 14 14 0,000 0,07467798 0,1030176 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,07467798 0,10294055 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,07467798 0,10286362 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,07467798 0,10278679 ! formation of primary germ layer GO:0001704 14 14 0,000 0,07467798 0,10271009 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,07467798 0,1026335 ! collagen fibril organization GO:0030199 14 14 0,000 0,07467798 0,10255702 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,07467798 0,10248065 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,07467798 0,1024044 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,07467798 0,10232827 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,07467798 0,10225224 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,07467798 0,10217633 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,07467798 0,10210053 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,07467798 0,10202485 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,07467798 0,10194927 ! regulation of cellular localization GO:0060341 86 85 1,000 0,07967321 0,10868818 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,07967321 0,10860779 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,07967321 0,10852752 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,07979919 0,10861884 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,07979919 0,10853868 ! positive regulation of ossification GO:0045778 15 15 0,000 0,07979919 0,10845864 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,07979919 0,10837871 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,07979919 0,1082989 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,07979919 0,10821921 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,07979919 0,10813964 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,07979919 0,10806018 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,07979919 0,10798084 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,07979919 0,10790162 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,07979919 0,10782251 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,07979919 0,10774352 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,07979919 0,10766465 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,07979919 0,10758589 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,07979919 0,10750724 ! heme metabolic process GO:0042168 15 15 0,000 0,07979919 0,10742871 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,07979919 0,1073503 ! chromosome condensation GO:0030261 15 15 0,000 0,07979919 0,107272 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,07979919 0,10719381 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,07979919 0,10711574 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,07979919 0,10703778 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,07979919 0,10695993 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,07979919 0,1068822 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,07979919 0,10680458 ! phospholipid transport GO:0015914 15 15 0,000 0,07979919 0,10672708 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,07979919 0,10664968 ! glutathione metabolic process GO:0006749 16 15 0,000 0,07979919 0,1065724 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,07979919 0,10649523 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,07979919 0,10641817 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,07979919 0,10634122 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,07979919 0,10626439 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,07979919 0,10618766 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,07979919 0,10611105 ! protein homooligomerization GO:0051260 15 15 0,000 0,07979919 0,10603454 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,07979919 0,10595815 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,0848928 0,11264034 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,0848928 0,1125593 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,0848928 0,11247838 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,0848928 0,11239758 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,0848928 0,11231689 ! circadian rhythm GO:0007623 16 16 0,000 0,0848928 0,11223632 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,0848928 0,11215587 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,0848928 0,11207552 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,0848928 0,1119953 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,0848928 0,11191519 ! vesicle targeting GO:0006903 17 16 0,000 0,0848928 0,11183519 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,0848928 0,11175531 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,0848928 0,11167554 ! iron ion homeostasis GO:0055072 16 16 0,000 0,0848928 0,11159589 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,0848928 0,11151635 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,0848928 0,11143692 ! cell fate specification GO:0001708 16 16 0,000 0,0848928 0,1113576 ! pentose metabolic process GO:0019321 16 16 0,000 0,0848928 0,1112784 ! fatty acid transport GO:0015908 16 16 0,000 0,0848928 0,11119931 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,0848928 0,11112034 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,0848928 0,11104147 ! cofactor catabolic process GO:0051187 16 16 0,000 0,0848928 0,11096272 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,0848928 0,11088408 ! polyol metabolic process GO:0019751 16 16 0,000 0,0848928 0,11080555 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,0848928 0,11072713 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,0848928 0,11064882 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,0848928 0,11057062 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,0848928 0,11049254 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,0848928 0,11041456 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,0848928 0,11033669 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,08621729 0,11197918 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,08954942 0,11622505 ! DNA replication GO:0006260 91 91 1,000 0,08954942 0,11614326 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,08995895 0,11659237 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,08995895 0,11651044 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,08995895 0,11642862 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,08995895 0,11634691 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,08995895 0,11626532 ! leukocyte adhesion GO:0007159 17 17 0,000 0,08995895 0,11618385 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,08995895 0,11610249 ! sensory perception of smell GO:0007608 17 17 0,000 0,08995895 0,11602124 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,08995895 0,11594011 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,08995895 0,11585909 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,08995895 0,11577818 ! neural crest cell development GO:0014032 19 17 0,000 0,08995895 0,11569738 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,08995895 0,1156167 GO:0002764|immune response-regulating signal transduction, ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,08995895 0,11553613 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,08995895 0,11545568 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,08995895 0,11537533 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,08995895 0,1152951 ! embryonic organ development GO:0048568 17 17 0,000 0,08995895 0,11521498 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,08995895 0,11513497 ! liver development GO:0001889 17 17 0,000 0,08995895 0,11505507 ! gene silencing GO:0016458 17 17 0,000 0,08995895 0,11497528 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,09122997 0,11651894 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,09122997 0,11643825 ! regulation of response to stress GO:0080134 97 94 1,000 0,09461929 0,12068052 ! epidermis development GO:0008544 94 94 1,000 0,09461929 0,12059706 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,09499779 0,12099581 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,09499779 0,12091225 ! meiosis I GO:0007127 18 18 0,000 0,09499779 0,1208288 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,09499779 0,12074547 ! membrane docking GO:0022406 18 18 0,000 0,09499779 0,12066226 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,09499779 0,12057916 ! response to calcium ion GO:0051592 18 18 0,000 0,09499779 0,12049617 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,09499779 0,1204133 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,09499779 0,12033054 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,09499779 0,12024789 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,09499779 0,12016536 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,09499779 0,12008295 ! ceramide metabolic process GO:0006672 18 18 0,000 0,09499779 0,12000064 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,09499779 0,11991845 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,09499779 0,11983637 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,09499779 0,1197544 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,09499779 0,11967255 ! BMP signaling pathway GO:0030509 18 18 0,000 0,09499779 0,1195908 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,09499779 0,11950917 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,09499779 0,11942765 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,09499779 0,11934624 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,10000946 0,12555684 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,10000946 0,12547137 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,10000946 0,12538602 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,10000946 0,12530078 ! peroxisome organization GO:0007031 19 19 0,000 0,10000946 0,12521565 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,10000946 0,12513065 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,10000946 0,12504576 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,10000946 0,12496098 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,10000946 0,12487632 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,10000946 0,12479177 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,10000946 0,12470734 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,10000946 0,12462302 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,10000946 0,12453881 ! eye morphogenesis GO:0048592 19 19 0,000 0,10000946 0,12445472 ! placenta development GO:0001890 19 19 0,000 0,10000946 0,12437074 ! vesicle localization GO:0051648 20 19 0,000 0,10000946 0,12428688 ! endocytosis GO:0006897 99 98 1,000 0,1015067 0,12606256 GO:0010324|membrane invagination, ! ectoderm development GO:0007398 99 99 1,000 0,10325036 0,1281417 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,10499411 0,13021813 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,10499411 0,13013056 ! negative regulation of binding GO:0051100 21 20 0,000 0,10499411 0,13004311 ! organic ether metabolic process GO:0018904 20 20 0,000 0,10499411 0,12995577 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,10499411 0,12986855 ! nucleus organization GO:0006997 20 20 0,000 0,10499411 0,12978145 ! phagocytosis GO:0006909 21 20 0,000 0,10499411 0,12969447 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,10499411 0,1296076 ! protein targeting to membrane GO:0006612 22 20 0,000 0,10499411 0,12952084 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,10499411 0,12943421 ! chromatin remodeling GO:0006338 20 20 0,000 0,10499411 0,12934769 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,10499411 0,12926128 ! lipid oxidation GO:0034440 20 20 0,000 0,10499411 0,12917499 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,10499411 0,12908882 ! RNA modification GO:0009451 20 20 0,000 0,10499411 0,12900276 ! single fertilization GO:0007338 21 20 0,000 0,10499411 0,12891682 ! regulation of B cell activation GO:0050864 20 20 0,000 0,10499411 0,12883099 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,10500247 0,12875552 ! response to other organism GO:0051707 101 100 1,000 0,10500247 0,12866991 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,10995187 0,13464538 ! mRNA catabolic process GO:0006402 21 21 0,000 0,10995187 0,13455597 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,10995187 0,13446668 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,10995187 0,13437751 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,10995187 0,13428846 ! Notch signaling pathway GO:0007219 22 21 0,000 0,10995187 0,13419953 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,10995187 0,13411072 ! ear morphogenesis GO:0042471 21 21 0,000 0,10995187 0,13402202 ! organic anion transport GO:0015711 21 21 0,000 0,10995187 0,13393344 ! cholesterol transport GO:0030301 21 21 0,000 0,10995187 0,13384497 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,10995187 0,13375663 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,10995187 0,1336684 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,10995187 0,13358028 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,10995187 0,13349229 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,10995187 0,1334044 ! regulation of proteolysis GO:0030162 21 21 0,000 0,10995187 0,13331664 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,10995187 0,13322899 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,10995187 0,13314145 ! RNA export from nucleus GO:0006405 22 22 0,000 0,11488288 0,13902111 ! sister chromatid segregation GO:0000819 22 22 0,000 0,11488288 0,13892989 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,11488288 0,13883879 ! regulation of ion transport GO:0043269 22 22 0,000 0,11488288 0,13874781 ! odontogenesis GO:0042476 22 22 0,000 0,11488288 0,13865694 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,11488288 0,1385662 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,11488288 0,13847557 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,11488288 0,13838507 ! spindle organization GO:0007051 22 22 0,000 0,11488288 0,13829468 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,11488288 0,13820441 ! cell chemotaxis GO:0060326 23 22 0,000 0,11488288 0,13811425 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,11488288 0,13802422 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,11488288 0,1379343 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,11488288 0,1378445 ! biopolymer methylation GO:0043414 22 22 0,000 0,11488288 0,13775482 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,11488288 0,13766525 ! detection of external stimulus GO:0009581 23 22 0,000 0,11488288 0,1375758 ! neuron migration GO:0001764 22 22 0,000 0,11488288 0,13748646 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,11488288 0,13739724 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,11488288 0,13730814 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,11488288 0,13721915 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,11488288 0,13713028 ! aerobic respiration GO:0009060 22 22 0,000 0,11488288 0,13704152 ! cytokine production GO:0001816 22 22 0,000 0,11488288 0,13695288 ! cytokinesis GO:0000910 23 22 0,000 0,11488288 0,13686435 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,11488288 0,13677594 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,11978729 0,14252291 ! viral infectious cycle GO:0019058 23 23 0,000 0,11978729 0,14243095 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,11978729 0,14233912 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,11978729 0,14224741 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,11978729 0,14215581 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,11978729 0,14206434 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,11978729 0,14197298 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,11978729 0,14188174 ! lipid homeostasis GO:0055088 23 23 0,000 0,11978729 0,14179061 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,11978729 0,1416996 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,11978729 0,14160871 ! gliogenesis GO:0042063 24 24 0,000 0,12466524 0,14728079 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,12466524 0,14718644 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,12466524 0,14709221 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,12466524 0,1469981 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,12466524 0,14690412 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,12466524 0,14681025 ! fertilization GO:0009566 25 24 0,000 0,12466524 0,1467165 ! maintenance of protein location GO:0045185 25 24 0,000 0,12466524 0,14662287 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,12466524 0,14652936 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,12951686 0,15213485 ! negative regulation of secretion GO:0051048 26 25 0,000 0,12951686 0,15203795 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,12951686 0,15194117 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,12951686 0,15184451 ! cellular component disassembly GO:0022411 26 25 0,000 0,12951686 0,15174798 ! endosome transport GO:0016197 25 25 0,000 0,12951686 0,15165157 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,12951686 0,15155529 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,12951686 0,15145912 ! excretion GO:0007588 25 25 0,000 0,12951686 0,15136308 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,12951686 0,15126716 ! gastrulation GO:0007369 25 25 0,000 0,12951686 0,15117136 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,12951686 0,15107568 ! regulation of endocytosis GO:0030100 25 25 0,000 0,12951686 0,15098012 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,12951686 0,15088469 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,12951686 0,15078937 ! positive regulation of defense response GO:0031349 26 26 0,000 0,1343423 0,15630862 ! glycolysis GO:0006096 26 26 0,000 0,1343423 0,15621 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,1343423 0,15611151 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,1343423 0,15601314 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,1343423 0,1559149 ! cellular defense response GO:0006968 26 26 0,000 0,1343423 0,15581677 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,1343423 0,15571878 ! regulation of protein secretion GO:0050708 26 26 0,000 0,1343423 0,1556209 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,1343423 0,15552315 GO:0035150|regulation of tube size, ! maintenance of location in cell GO:0051651 27 26 0,000 0,1343423 0,15542552 ! chloride transport GO:0006821 27 27 0,000 0,13914168 0,16087712 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,13914168 0,16077625 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,13914168 0,16067552 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,13914168 0,1605749 ! peptide metabolic process GO:0006518 29 27 0,000 0,13914168 0,16047442 ! inner ear development GO:0048839 27 27 0,000 0,13914168 0,16037406 ! defense response to bacterium GO:0042742 27 27 0,000 0,13914168 0,16027383 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,13914168 0,16017372 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,13914168 0,16007373 ! cell growth GO:0016049 27 27 0,000 0,13914168 0,15997388 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,14391516 0,16535887 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! regulation of muscle contraction GO:0006937 28 28 0,000 0,14391516 0,16525585 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,14391516 0,16515295 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,14391516 0,16505018 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,14391516 0,16494753 ! cartilage development GO:0051216 29 28 0,000 0,14391516 0,16484502 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,14866285 0,17017742 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,14866285 0,17007178 ! leukocyte migration GO:0050900 30 29 0,000 0,14866285 0,16996628 ! antigen processing and presentation GO:0019882 29 29 0,000 0,14866285 0,16986091 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,14866285 0,16975566 ! tRNA processing GO:0008033 29 29 0,000 0,14866285 0,16965055 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,14866285 0,16954557 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,14866285 0,16944072 ! transition metal ion transport GO:0000041 31 30 0,000 0,15338491 0,1747147 ! RNA catabolic process GO:0006401 30 30 0,000 0,15338491 0,17460679 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,15338491 0,17449901 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,15338491 0,17439136 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,15338491 0,17428384 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,15338491 0,17417646 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,15338491 0,17406921 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,15338491 0,17396209 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,15338491 0,1738551 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,15338491 0,17374824 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,15338491 0,17364152 ! establishment of organelle localization GO:0051656 31 30 0,000 0,15338491 0,17353492 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,15808146 0,17873873 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,15808146 0,17862914 ! ion transmembrane transport GO:0034220 31 31 0,000 0,15808146 0,17851969 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,15808146 0,17841037 ! digestion GO:0007586 31 31 0,000 0,15808146 0,17830118 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,15808146 0,17819213 ! regulation of heart contraction GO:0008016 31 31 0,000 0,15808146 0,17808321 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,15808146 0,17797443 ! camera-type eye development GO:0043010 31 31 0,000 0,15808146 0,17786577 ! extracellular matrix organization GO:0030198 31 31 0,000 0,15808146 0,17775725 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,15808146 0,17764886 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,15808146 0,17754061 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,15808146 0,17743248 ! cell redox homeostasis GO:0045454 32 32 0,000 0,16275264 0,18256428 ! glucose catabolic process GO:0006007 32 32 0,000 0,16275264 0,18245323 ! lipid modification GO:0030258 32 32 0,000 0,16275264 0,18234232 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,16275264 0,18223154 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,16275264 0,1821209 ! cell maturation GO:0048469 32 32 0,000 0,16275264 0,18201039 ! nuclear export GO:0051168 32 32 0,000 0,16275264 0,18190001 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,16275264 0,18178977 ! maintenance of location GO:0051235 33 32 0,000 0,16275264 0,18167966 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,16739858 0,18675278 ! amino acid transport GO:0006865 33 33 0,000 0,16739858 0,1866398 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,16739858 0,18652696 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,16739858 0,18641425 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,16739858 0,18630168 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,16739858 0,18618925 ! regulation of actin filament length GO:0030832 34 34 0,000 0,17201942 0,19121338 ! muscle cell differentiation GO:0042692 35 34 0,000 0,17201942 0,19109812 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,17201942 0,190983 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,17201942 0,19086802 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,17201942 0,19075318 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,17201942 0,19063847 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,17201942 0,19052391 ! detection of stimulus GO:0051606 36 34 0,000 0,17201942 0,19040948 ! acute inflammatory response GO:0002526 35 35 0,000 0,17661528 0,19537932 ! regulation of cellular component size GO:0032535 35 35 0,000 0,17661528 0,19526212 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,17661528 0,19514506 ! inorganic anion transport GO:0015698 35 35 0,000 0,17661528 0,19502813 ! regulation of immune effector process GO:0002697 35 35 0,000 0,17661528 0,19491135 ! hydrogen transport GO:0006818 36 36 0,000 0,18118629 0,19983623 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,18118629 0,19971671 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,18118629 0,19959734 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,18118629 0,1994781 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,18118629 0,19935901 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,18118629 0,19924006 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,18118629 0,19912125 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,18118629 0,19900259 ! activation of immune response GO:0002253 36 36 0,000 0,18118629 0,19888406 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,1857326 0,20375309 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,1857326 0,20363188 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,1857326 0,20351081 ! eye development GO:0001654 37 37 0,000 0,1857326 0,20338989 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,1857326 0,20326911 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,1857326 0,20314848 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,1857326 0,20302799 ! positive regulation of secretion GO:0051047 39 38 0,000 0,19025433 0,20784749 ! neurotransmitter transport GO:0006836 40 38 0,000 0,19025433 0,20772436 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,19025433 0,20760138 ! exocytosis GO:0006887 40 38 0,000 0,19025433 0,20747853 ! chromosome segregation GO:0007059 38 38 0,000 0,19025433 0,20735584 ! hexose catabolic process GO:0019320 38 38 0,000 0,19025433 0,20723329 ! RNA elongation GO:0006354 38 38 0,000 0,19025433 0,20711088 ! meiotic cell cycle GO:0051321 38 38 0,000 0,19025433 0,20698862 ! regulation of neurological system process GO:0031644 38 38 0,000 0,19025433 0,2068665 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,1947516 0,2116316 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,1947516 0,21150689 ! response to unfolded protein GO:0006986 39 39 0,000 0,1947516 0,21138233 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,1947516 0,21125791 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,1947516 0,21113364 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,1947516 0,21100952 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,1947516 0,21088554 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,1947516 0,21076171 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,1947516 0,21063803 ! developmental maturation GO:0021700 39 39 0,000 0,1947516 0,21051448 ! limb development GO:0060173 39 39 0,000 0,1947516 0,21039109 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,19922455 0,21509715 ! DNA catabolic process GO:0006308 41 40 0,000 0,19922455 0,21497122 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,19922455 0,21484543 ! organelle localization GO:0051640 41 40 0,000 0,19922455 0,21471979 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,2036733 0,21938626 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,2036733 0,21925811 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,2036733 0,21913012 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,2036733 0,21900227 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,2036733 0,21887457 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,2036733 0,21874702 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,2036733 0,21861962 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,20809798 0,22323899 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,20809798 0,22310912 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,20809798 0,22297941 ! protein ubiquitination GO:0016567 43 42 0,000 0,20809798 0,22284984 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,20809798 0,22272043 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,20809798 0,22259117 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,21249873 0,22716656 ! alcohol catabolic process GO:0046164 43 43 0,000 0,21249873 0,22703487 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,21249873 0,22690333 ! mRNA transport GO:0051028 44 44 0,000 0,21687565 0,23144286 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,21687565 0,23130893 ! vitamin metabolic process GO:0006766 44 44 0,000 0,21687565 0,23117515 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,21687565 0,23104152 ! amine biosynthetic process GO:0009309 46 45 0,000 0,22122889 0,23554295 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,22122889 0,23540695 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,22122889 0,23527111 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,22122889 0,23513543 ! protein processing GO:0016485 45 45 0,000 0,22122889 0,23499991 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,22555856 0,23946107 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,22555856 0,23932322 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,22555856 0,23918552 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,22986479 0,24361174 ! regulation of blood pressure GO:0008217 48 47 0,000 0,22986479 0,24347173 ! amine transport GO:0015837 47 47 0,000 0,22986479 0,24333188 ! calcium ion transport GO:0006816 48 48 0,000 0,2341477 0,24772343 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,2341477 0,2475813 ! DNA recombination GO:0006310 48 48 0,000 0,2341477 0,24743934 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,23840742 0,25179649 ! divalent metal ion transport GO:0070838 49 49 0,000 0,23840742 0,25165228 ! response to bacterium GO:0009617 50 49 0,000 0,23840742 0,25150823 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,23840742 0,25136434 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,23840742 0,25122062 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,24264406 0,25553886 ! negative regulation of transport GO:0051051 51 50 0,000 0,24264406 0,25539292 ! chromatin assembly GO:0031497 50 50 0,000 0,24264406 0,25524715 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,24264406 0,25510155 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,24264406 0,25495611 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,24264406 0,25481083 ! transcription initiation GO:0006352 50 50 0,000 0,24264406 0,25466572 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,24685776 0,25894072 ! positive regulation of immune response GO:0050778 51 51 0,000 0,24685776 0,25879343 ! rRNA metabolic process GO:0016072 51 51 0,000 0,24685776 0,2586463 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,24685776 0,25849934 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,24685776 0,25835255 ! protein maturation GO:0051604 51 51 0,000 0,24685776 0,25820593 ! RNA localization GO:0006403 52 52 0,000 0,25104862 0,2624405 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,25104862 0,26229173 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,25104862 0,26214312 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,25104862 0,26199468 ! sodium ion transport GO:0006814 53 53 0,000 0,25521677 0,26619384 ! tRNA metabolic process GO:0006399 53 53 0,000 0,25521677 0,26604328 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,25521677 0,26589288 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,25521677 0,26574266 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,25521677 0,26559261 ! hormone metabolic process GO:0042445 55 54 0,000 0,25936234 0,26975439 ! sulfur metabolic process GO:0006790 55 54 0,000 0,25936234 0,26960225 ! nucleosome organization GO:0034728 55 55 0,000 0,26348543 0,27373374 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,26348543 0,27357952 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,26758617 0,27768092 ! ATP metabolic process GO:0046034 57 57 0,000 0,27166468 0,28175464 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,27166468 0,28159617 ! innate immune response GO:0045087 58 58 0,000 0,27572107 0,2856402 ! carboxylic acid transport GO:0046942 59 59 0,000 0,27975545 0,28965691 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,27975545 0,28949427 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,27975545 0,28933182 ! potassium ion transport GO:0006813 60 60 0,000 0,28376796 0,29331708 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,28376796 0,29315266 ! cellular respiration GO:0045333 62 61 0,000 0,28775869 0,29710884 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,28775869 0,29694248 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,28775869 0,29677631 ! lipid transport GO:0006869 62 62 0,000 0,29172778 0,30070151 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,29172778 0,30053342 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,29172778 0,30036553 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,29172778 0,30019782 ! regulation of secretion GO:0051046 65 63 0,000 0,29567532 0,30409019 ! glucose metabolic process GO:0006006 63 63 0,000 0,29567532 0,30392059 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,29567532 0,30375118 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,29567532 0,30358196 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,29960144 0,30744178 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,29960144 0,3072707 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,29960144 0,3070998 ! anion transport GO:0006820 65 65 0,000 0,30350624 0,3109294 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,30350624 0,31075667 ! regulation of hormone levels GO:0010817 66 65 0,000 0,30350624 0,31058412 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,30738984 0,31438373 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,30738984 0,31420936 ! DNA packaging GO:0006323 66 66 0,000 0,30738984 0,31403519 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,30738984 0,31386121 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,31125236 0,31762907 ! muscle contraction GO:0006936 67 67 0,000 0,31125236 0,31745329 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,31125236 0,31727771 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,3150939 0,32101606 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,3150939 0,32083871 ! sensory perception of sound GO:0007605 71 69 0,000 0,31891457 0,32454973 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,32271449 0,32823555 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,32649377 0,33189631 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,32649377 0,33171335 ! ribosome biogenesis GO:0042254 71 71 0,000 0,32649377 0,33153058 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,32649377 0,33134802 ! secretion by cell GO:0032940 75 72 0,000 0,3302525 0,33497818 ! muscle system process GO:0003012 72 72 0,000 0,3302525 0,33479393 ! regulation of cytokine production GO:0001817 72 72 0,000 0,3302525 0,33460987 ! electron transport chain GO:0022900 75 74 0,000 0,3377088 0,34197655 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,3377088 0,34178875 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,34140658 0,34534156 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,34140658 0,34515212 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,34508425 0,34867887 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,3523797 0,35585522 ! regulation of immune response GO:0050776 78 78 0,000 0,3523797 0,35566034 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,35959599 0,36274517 ! lipid catabolic process GO:0016042 82 81 0,000 0,36317472 0,36615482 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,37027386 0,3731081 ! ncRNA processing GO:0034470 83 83 0,000 0,37027386 0,37290422 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,37379447 0,37624424 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,37729591 0,37956133 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,38077829 0,38285564 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,38077829 0,38264688 ! male gamete generation GO:0048232 90 88 0,000 0,38768625 0,38937643 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,38768625 0,38916436 ! chemotaxis GO:0006935 90 89 0,000 0,39111203 0,39238948 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,39451915 0,39559238 ! visual perception GO:0007601 93 92 0,000 0,40127779 0,40215061 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,40127779 0,40193205 ! cofactor metabolic process GO:0051186 95 94 0,000 0,40796295 0,40840614 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,42111593 0,42134455 ! regulation of system process GO:0044057 98 98 0,000 0,42111593 0,42111593