pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6545-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cellular response to hormone stimulus GO:0032870 167 82 7,000 3,845E-11 9,252E-08 ! hormone-mediated signaling GO:0009755 74 41 5,000 9,588E-10 1,153E-06 ! regulation of intracellular protein transport GO:0033157 80 42 5,000 1,116E-09 8,953E-07 ! regulation of protein export from nucleus GO:0046825 10 7 3,000 1,374E-09 8,264E-07 ! organ growth GO:0035265 15 7 3,000 1,374E-09 6,612E-07 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 1,374E-09 5,51E-07 GO:0046676|negative regulation of insulin secretion, ! regulation of nucleocytoplasmic transport GO:0046822 85 46 5,000 1,977E-09 6,796E-07 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 2,743E-09 8,248E-07 ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 4,291E-09 1,147E-06 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 4,927E-09 1,185E-06 ! regulation of intracellular transport GO:0032386 101 57 5,000 7,492E-09 1,639E-06 ! DNA damage checkpoint GO:0000077 71 33 4,000 2,148E-08 4,308E-06 ! DNA integrity checkpoint GO:0031570 75 36 4,000 3,392E-08 6,278E-06 ! carbohydrate homeostasis GO:0033500 53 38 4,000 4,499E-08 7,731E-06 GO:0042593|glucose homeostasis, ! negative regulation of hormone secretion GO:0046888 25 17 3,000 9,163E-08 1,47E-05 ! regulation of protein transport GO:0051223 154 87 5,000 9,812E-08 1,475E-05 GO:0070201|regulation of establishment of protein localization, ! positive regulation of hormone secretion GO:0046887 32 19 3,000 1,487E-07 2,104E-05 ! regulation of protein localization GO:0032880 176 97 5,000 1,882E-07 2,515E-05 ! DNA damage response, signal transduction GO:0042770 128 60 4,000 4,685E-07 5,933E-05 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 4,685E-07 5,636E-05 ! regulation of insulin secretion GO:0050796 37 25 3,000 4,795E-07 5,494E-05 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 6,627E-07 7,248E-05 ! activation of MAPK activity GO:0000187 115 67 4,000 8,17E-07 8,546E-05 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 8,916E-07 8,938E-05 ! regulation of peptide secretion GO:0002791 47 29 3,000 8,934E-07 8,598E-05 ! cell cycle checkpoint GO:0000075 137 69 4,000 9,47E-07 8,763E-05 ! triglyceride metabolic process GO:0006641 43 31 3,000 1,179E-06 1,051E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 1,903E-06 1,636E-04 ! negative regulation of secretion GO:0051048 63 35 3,000 1,947E-06 1,615E-04 ! neutral lipid metabolic process GO:0006638 50 35 3,000 1,947E-06 1,561E-04 GO:0006639|acylglycerol metabolic process, ! glycerol ether metabolic process GO:0006662 53 37 3,000 2,446E-06 1,899E-04 ! negative regulation of transport GO:0051051 153 84 4,000 2,525E-06 1,898E-04 ! organic ether metabolic process GO:0018904 55 39 3,000 3,035E-06 2,212E-04 ! regulation of hormone secretion GO:0046883 62 40 3,000 3,365E-06 2,381E-04 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 2,000 3,477E-06 2,39E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 4,518E-06 3,019E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 7,151E-06 4,65E-04 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 8,785E-06 5,562E-04 ! response to UV GO:0009411 104 53 3,000 1,051E-05 6,487E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,065E-05 6,405E-04 ! regulation of multicellular organism growth GO:0040014 85 55 3,000 1,22E-05 7,159E-04 ! positive regulation of secretion GO:0051047 95 59 3,000 1,615E-05 9,254E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,775E-05 9,933E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,775E-05 9,708E-04 ! multicellular organism reproduction GO:0032504 111 64 3,000 2,233E-05 1,194E-03 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,389E-05 1,25E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,389E-05 1,223E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 2,679E-05 1,343E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 2,743E-05 1,347E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 3,01E-05 1,448E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 3,129E-05 1,476E-03 ! protein tetramerization GO:0051262 52 24 2,000 3,129E-05 1,448E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 4,004E-05 1,818E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 4,004E-05 1,784E-03 ! protein oligomerization GO:0051259 139 78 3,000 4,88E-05 2,135E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 5,597E-05 2,405E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 6,42E-05 2,71E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 6,42E-05 2,663E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 6,42E-05 2,618E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 6,42E-05 2,574E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 6,42E-05 2,532E-03 ! negative regulation of growth GO:0045926 155 84 3,000 6,525E-05 2,532E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 7,555E-05 2,885E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 9,082E-05 3,414E-03 ! male meiosis GO:0007140 7 6 1,000 9,614E-05 3,559E-03 ! male sex determination GO:0030238 15 6 1,000 9,614E-05 3,505E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 9,614E-05 3,452E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 9,614E-05 3,402E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 1,054E-04 3,675E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,08E-04 3,711E-03 ! hormone metabolic process GO:0042445 157 97 3,000 1,143E-04 3,872E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,173E-04 3,919E-03 ! interphase GO:0051325 213 98 3,000 1,189E-04 3,919E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,344E-04 4,369E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,344E-04 4,311E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,344E-04 4,254E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,344E-04 4,199E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,344E-04 4,145E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,344E-04 4,092E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 1,483E-04 4,46E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! T cell differentiation GO:0030217 81 41 2,000 1,597E-04 4,744E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,789E-04 5,248E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,789E-04 5,185E-03 ! ER overload response GO:0006983 12 8 1,000 1,789E-04 5,123E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,789E-04 5,063E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,11E-04 5,904E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,254E-04 6,232E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,254E-04 6,161E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 2,254E-04 6,092E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,254E-04 6,024E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 2,296E-04 6,07E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,296E-04 6,004E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 2,296E-04 5,94E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 2,296E-04 5,876E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 2,296E-04 5,815E-03 ! receptor clustering GO:0043113 18 9 1,000 2,296E-04 5,754E-03 ! motor axon guidance GO:0008045 16 9 1,000 2,296E-04 5,695E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 2,296E-04 5,637E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,558E-04 6,217E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,865E-04 6,893E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,865E-04 6,825E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 2,865E-04 6,758E-03 ! pathogenesis GO:0009405 13 10 1,000 2,865E-04 6,693E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,865E-04 6,628E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,865E-04 6,565E-03 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 2,865E-04 6,503E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 3,063E-04 6,888E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 3,496E-04 7,788E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 3,496E-04 7,717E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 3,496E-04 7,647E-03 ! activation of phospholipase C activity GO:0007202 103 54 2,000 3,629E-04 7,865E-03 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 3,831E-04 8,23E-03 ! regulation of DNA replication GO:0006275 101 56 2,000 4,04E-04 8,603E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 4,188E-04 8,839E-03 ! virus-host interaction GO:0019048 29 12 1,000 4,188E-04 8,762E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 4,188E-04 8,687E-03 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 4,188E-04 8,613E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 4,188E-04 8,54E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 4,257E-04 8,607E-03 ! positive regulation of cell migration GO:0030335 126 57 2,000 4,257E-04 8,535E-03 ! regulation of phospholipase activity GO:0010517 106 57 2,000 4,257E-04 8,465E-03 ! positive regulation of lipase activity GO:0060193 108 58 2,000 4,481E-04 8,837E-03 ! response to X-ray GO:0010165 25 13 1,000 4,942E-04 9,666E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 4,942E-04 9,588E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 4,942E-04 9,511E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 4,942E-04 9,436E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 4,942E-04 9,362E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,198E-04 9,77E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 5,714E-04 0,01065763 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 5,756E-04 0,01065216 ! response to gamma radiation GO:0010332 28 14 1,000 5,756E-04 0,01057085 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 5,756E-04 0,01049077 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 5,756E-04 0,01041189 ! positive regulation of cell motion GO:0051272 146 64 2,000 5,984E-04 0,01074483 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 6,63E-04 0,01181613 ! G1/S transition checkpoint GO:0031575 40 15 1,000 6,63E-04 0,01172925 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 6,843E-04 0,01201752 ! negative regulation of kinase activity GO:0033673 131 68 2,000 7,146E-04 0,01245821 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 7,146E-04 0,01236859 ! regulation of lipase activity GO:0060191 130 68 2,000 7,146E-04 0,01228024 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 7,565E-04 0,01290809 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 7,565E-04 0,01281719 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 7,565E-04 0,01272755 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 7,565E-04 0,01263917 ! regulation of caspase activity GO:0043281 122 72 2,000 8,441E-04 0,01400698 ! negative regulation of transferase activity GO:0051348 140 72 2,000 8,441E-04 0,01391104 ! signal complex assembly GO:0007172 41 17 1,000 8,559E-04 0,01400882 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 8,559E-04 0,01391417 ! learning or memory GO:0007611 147 73 2,000 8,787E-04 0,01418912 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 9,142E-04 0,01466318 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 9,505E-04 0,01514523 ! lymphocyte differentiation GO:0030098 167 75 2,000 9,505E-04 0,01504559 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 9,613E-04 0,01511681 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 9,613E-04 0,01501865 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 9,613E-04 0,01492176 ! regulation of catabolic process GO:0009894 161 76 2,000 9,878E-04 0,01523433 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 1,073E-03 0,01643755 ! lipid phosphorylation GO:0046834 35 19 1,000 1,073E-03 0,01633352 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,073E-03 0,01623079 ! neuromuscular junction development GO:0007528 34 19 1,000 1,073E-03 0,01612935 ! G1 phase GO:0051318 40 19 1,000 1,073E-03 0,01602917 ! regulation of peptidase activity GO:0052547 134 79 2,000 1,105E-03 0,01641168 ! T cell activation GO:0042110 168 81 2,000 1,188E-03 0,01753396 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,19E-03 0,01745545 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,19E-03 0,01734966 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,19E-03 0,01724515 ! cellular response to starvation GO:0009267 33 20 1,000 1,19E-03 0,01714188 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,19E-03 0,01703985 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,19E-03 0,01693902 ! cell aging GO:0007569 44 21 1,000 1,313E-03 0,01858114 ! glutamate signaling pathway GO:0007215 41 22 1,000 1,442E-03 0,02028611 ! keratinization GO:0031424 28 22 1,000 1,442E-03 0,02016817 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 1,442E-03 0,02005159 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,442E-03 0,01993635 ! protein stabilization GO:0050821 39 22 1,000 1,442E-03 0,01982243 ! regulation of cell adhesion GO:0030155 212 89 2,000 1,558E-03 0,02130039 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,576E-03 0,02142946 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,576E-03 0,02130907 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 1,000 1,576E-03 0,02119002 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,576E-03 0,0210723 ! negative regulation of catabolic process GO:0009895 50 23 1,000 1,576E-03 0,02095588 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 1,717E-03 0,02269775 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,717E-03 0,02257372 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,717E-03 0,02245103 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,717E-03 0,02232968 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,863E-03 0,02410098 ! myelination GO:0042552 45 25 1,000 1,863E-03 0,02397209 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,863E-03 0,02384458 ! negative regulation of DNA replication GO:0008156 42 25 1,000 1,863E-03 0,02371842 ! receptor metabolic process GO:0043112 46 25 1,000 1,863E-03 0,02359359 ! response to starvation GO:0042594 42 25 1,000 1,863E-03 0,02347006 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,863E-03 0,02334782 ! negative regulation of cell development GO:0010721 73 25 1,000 1,863E-03 0,02322685 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 1,863E-03 0,02310712 ! cellular response to nutrient levels GO:0031669 41 25 1,000 1,863E-03 0,02298862 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 1,878E-03 0,02305802 ! leukocyte differentiation GO:0002521 202 96 2,000 1,935E-03 0,02363776 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 1,994E-03 0,02422465 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,015E-03 0,02436341 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,015E-03 0,02424159 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 2,015E-03 0,02412098 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,173E-03 0,02587885 ! mitochondrial membrane organization GO:0007006 57 27 1,000 2,173E-03 0,02575137 ! base-excision repair GO:0006284 41 27 1,000 2,173E-03 0,02562514 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,173E-03 0,02550014 ! cell cycle arrest GO:0007050 213 100 2,000 2,174E-03 0,02539625 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,336E-03 0,02715141 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 2,336E-03 0,02702087 ! regulation of pH GO:0006885 43 29 1,000 2,505E-03 0,02883583 ! ensheathment of neurons GO:0007272 57 30 1,000 2,679E-03 0,03069761 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,679E-03 0,03055213 ! regulation of B cell activation GO:0050864 50 30 1,000 2,679E-03 0,03040801 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 2,859E-03 0,03229907 GO:0043433|negative regulation of transcription factor activity, ! response to ionizing radiation GO:0010212 65 32 1,000 3,045E-03 0,03423472 ! peripheral nervous system development GO:0007422 64 32 1,000 3,045E-03 0,03407549 ! positive regulation of catabolic process GO:0009896 64 32 1,000 3,045E-03 0,03391774 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 3,236E-03 0,03588025 ! negative regulation of protein transport GO:0051224 69 33 1,000 3,236E-03 0,03571566 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 3,635E-03 0,03993183 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 3,635E-03 0,03975032 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 3,635E-03 0,03957045 ! calcium-mediated signaling GO:0019722 62 35 1,000 3,635E-03 0,03939221 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 3,842E-03 0,04145384 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 3,842E-03 0,04126878 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,842E-03 0,04108536 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 4,055E-03 0,04316957 ! negative regulation of DNA binding GO:0043392 68 37 1,000 4,055E-03 0,0429794 ! regulation of protein stability GO:0031647 73 37 1,000 4,055E-03 0,04279089 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 4,273E-03 0,04489674 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 4,273E-03 0,04470154 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 4,273E-03 0,04450802 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 4,497E-03 0,04663461 ! learning GO:0007612 77 39 1,000 4,497E-03 0,04643446 ! regulation of action potential in neuron GO:0019228 73 39 1,000 4,497E-03 0,04623602 ! negative regulation of binding GO:0051100 72 40 1,000 4,726E-03 0,04838248 ! maintenance of protein location GO:0045185 91 40 1,000 4,726E-03 0,04817747 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 4,96E-03 0,05035125 ! gliogenesis GO:0042063 88 41 1,000 4,96E-03 0,05013969 ! regulation of T cell proliferation GO:0042129 71 41 1,000 4,96E-03 0,0499299 ! keratinocyte differentiation GO:0030216 62 41 1,000 4,96E-03 0,04972186 ! regulation of T cell differentiation GO:0045580 70 41 1,000 4,96E-03 0,04951555 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 5,199E-03 0,05169114 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 5,444E-03 0,05390058 ! double-strand break repair GO:0006302 81 44 1,000 5,694E-03 0,0561432 ! B cell differentiation GO:0030183 107 44 1,000 5,694E-03 0,05591404 ! maintenance of location in cell GO:0051651 97 44 1,000 5,694E-03 0,05568675 ! epidermal cell differentiation GO:0009913 68 46 1,000 6,209E-03 0,06047937 ! endosome transport GO:0016197 108 47 1,000 6,474E-03 0,06280903 ! protein homooligomerization GO:0051260 76 47 1,000 6,474E-03 0,06255678 ! positive regulation of cell cycle GO:0045787 89 48 1,000 6,744E-03 0,06490849 ! mitochondrial transport GO:0006839 82 48 1,000 6,744E-03 0,06464989 ! activation of caspase activity GO:0006919 84 48 1,000 6,744E-03 0,06439334 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 6,744E-03 0,06413883 ! regulation of action potential GO:0001508 95 49 1,000 7,02E-03 0,06649523 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 7,02E-03 0,06623447 ! regulation of ossification GO:0030278 117 50 1,000 7,3E-03 0,06861162 ! negative regulation of immune system process GO:0002683 95 50 1,000 7,3E-03 0,06834465 ! regulation of angiogenesis GO:0045765 114 52 1,000 7,876E-03 0,07345054 ! positive regulation of growth GO:0045927 90 52 1,000 7,876E-03 0,07316695 ! synapse organization GO:0050808 85 52 1,000 7,876E-03 0,07288554 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 8,172E-03 0,07532947 ! positive regulation of caspase activity GO:0043280 95 55 1,000 8,777E-03 0,08060312 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 1,000 8,777E-03 0,08029664 ! aging GO:0007568 103 55 1,000 8,777E-03 0,07999249 ! heart morphogenesis GO:0003007 97 55 1,000 8,777E-03 0,07969063 ! skeletal muscle fiber development GO:0048741 111 56 1,000 9,087E-03 0,0821961 ! nucleotide-excision repair GO:0006289 83 56 1,000 9,087E-03 0,08188825 ! regulation of bone remodeling GO:0046850 137 57 1,000 9,402E-03 0,08441037 ! muscle fiber development GO:0048747 112 57 1,000 9,402E-03 0,08409657 ! lipid modification GO:0030258 97 57 1,000 9,402E-03 0,08378511 ! maintenance of location GO:0051235 118 57 1,000 9,402E-03 0,08347594 ! regulation of tissue remodeling GO:0034103 140 58 1,000 9,722E-03 0,0859978 ! viral reproductive process GO:0022415 126 62 1,000 0,01104901 0,09737702 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01104901 0,09702163 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01245104 0,10893529 ! actin filament organization GO:0007015 148 66 1,000 0,01245104 0,10854059 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01271912 0,11047725 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01271912 0,11007985 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01271912 0,1096853 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01271912 0,10929356 ! neuron fate determination GO:0048664 7 5 0,000 0,01271912 0,10890462 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01271912 0,10851843 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01271912 0,10813498 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01271912 0,10775422 ! polyol transport GO:0015791 12 5 0,000 0,01271912 0,10737613 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01271912 0,10700069 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01271912 0,10662787 ! response to superoxide GO:0000303 10 5 0,000 0,01271912 0,10625763 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01271912 0,10588996 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01271912 0,10552482 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01271912 0,10516219 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01271912 0,10480205 ! female meiosis GO:0007143 7 5 0,000 0,01271912 0,10444436 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01271912 0,10408911 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01271912 0,10373627 ! cobalt ion transport GO:0006824 11 5 0,000 0,01271912 0,1033858 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01271912 0,1030377 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01271912 0,10269194 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01271912 0,10234849 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01271912 0,10200733 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01271912 0,10166843 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01271912 0,10133178 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01271912 0,10099735 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01271912 0,10066513 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01271912 0,10033508 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01271912 0,10000718 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01271912 0,09968143 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01271912 0,09935779 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01271912 0,09903624 ! negative chemotaxis GO:0050919 14 5 0,000 0,01271912 0,09871677 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01271912 0,09839935 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01271912 0,09808397 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01271912 0,0977706 ! behavioral response to pain GO:0048266 9 5 0,000 0,01271912 0,09745923 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01271912 0,09714984 ! Notch receptor processing GO:0007220 8 5 0,000 0,01271912 0,0968424 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01271912 0,0965369 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,01271912 0,09623333 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01271912 0,09593166 ! copulation GO:0007620 9 5 0,000 0,01271912 0,09563187 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01271912 0,09533395 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01271912 0,09503788 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01271912 0,09474365 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01271912 0,09445123 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01271912 0,09416061 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01271912 0,09387177 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01271912 0,0935847 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01271912 0,09329938 ! grooming behavior GO:0007625 6 5 0,000 0,01271912 0,0930158 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01271912 0,09273393 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01271912 0,09245377 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01271912 0,0921753 ! response to protozoan GO:0001562 10 5 0,000 0,01271912 0,09189849 ! lymph vessel development GO:0001945 10 5 0,000 0,01271912 0,09162335 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01271912 0,09134985 ! endochondral ossification GO:0001958 16 5 0,000 0,01271912 0,09107797 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01271912 0,09080771 ! parathyroid gland development GO:0060017 13 5 0,000 0,01271912 0,09053905 ! anagen GO:0042640 6 5 0,000 0,01271912 0,09027197 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01271912 0,09000647 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01271912 0,08974252 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01271912 0,08948011 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01271912 0,08921924 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01271912 0,08895988 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01271912 0,08870202 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01271912 0,08844566 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01271912 0,08819077 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01271912 0,08793735 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01271912 0,08768538 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01271912 0,08743485 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01271912 0,08718575 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01271912 0,08693806 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01271912 0,08669178 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01271912 0,08644689 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01271912 0,08620338 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01271912 0,08596123 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01271912 0,08572044 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01271912 0,085481 ! histidine catabolic process GO:0006548 6 5 0,000 0,01271912 0,08524289 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01271912 0,08500611 ! microvillus organization GO:0032528 7 5 0,000 0,01271912 0,08477063 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01271912 0,08453646 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01271912 0,08430358 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01271912 0,08407197 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01271912 0,08384164 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01271912 0,08361256 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01271912 0,08338474 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01271912 0,08315815 ! polyol catabolic process GO:0046174 7 5 0,000 0,01271912 0,08293279 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01271912 0,08270864 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01271912 0,08248571 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01271912 0,08226397 ! muscle cell migration GO:0014812 8 5 0,000 0,01271912 0,08204343 ! mitochondrial fission GO:0000266 8 5 0,000 0,01271912 0,08182406 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01271912 0,08160586 ! mRNA transcription GO:0009299 9 5 0,000 0,01271912 0,08138882 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01271912 0,08117294 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01271912 0,0809582 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01271912 0,08074459 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01271912 0,0805321 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01271912 0,08032073 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01271912 0,08011047 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01271912 0,0799013 ! response to food GO:0032094 6 5 0,000 0,01271912 0,07969322 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01271912 0,07948623 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01271912 0,07928031 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01271912 0,07907545 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01271912 0,07887164 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01271912 0,07866889 ! forebrain neuron development GO:0021884 13 5 0,000 0,01271912 0,07846717 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01271912 0,07826649 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01271912 0,07806683 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01271912 0,07786819 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01271912 0,07767055 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01271912 0,07747392 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01271912 0,07727828 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01271912 0,07708362 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01271912 0,07688995 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01271912 0,07669724 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01271912 0,0765055 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01271912 0,07631471 ! basic amino acid transport GO:0015802 11 5 0,000 0,01271912 0,07612487 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01271912 0,07593598 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01271912 0,07574802 ! depyrimidination GO:0045008 10 5 0,000 0,01271912 0,07556098 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01271912 0,07537487 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01271912 0,07518968 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01271912 0,07500539 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01271912 0,074822 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01271912 0,07463951 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01271912 0,0744579 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01271912 0,07427718 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01271912 0,07409733 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01271912 0,07391835 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01271912 0,07374024 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01271912 0,07356298 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01271912 0,07338657 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01271912 0,073211 ! response to arsenic GO:0046685 10 5 0,000 0,01271912 0,07303627 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01271912 0,07286238 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01271912 0,07268931 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01271912 0,07251706 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01271912 0,07234562 ! response to cadmium ion GO:0046686 7 5 0,000 0,01271912 0,072175 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01271912 0,07200517 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01271912 0,07183615 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01271912 0,07166791 ! decidualization GO:0046697 11 5 0,000 0,01271912 0,07150046 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01271912 0,0713338 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01271912 0,0711679 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01271912 0,07100278 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01271912 0,07083842 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01271912 0,07067482 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01271912 0,07051198 ! neural tube patterning GO:0021532 7 5 0,000 0,01271912 0,07034988 ! embryonic cleavage GO:0040016 6 5 0,000 0,01271912 0,07018853 ! peroxisome fission GO:0016559 5 5 0,000 0,01271912 0,07002791 ! histone demethylation GO:0016577 10 5 0,000 0,01271912 0,06986803 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01271912 0,06970888 ! mitotic recombination GO:0006312 9 5 0,000 0,01271912 0,06955045 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01271912 0,06939274 ! metaphase plate congression GO:0051310 7 5 0,000 0,01271912 0,06923574 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01271912 0,06907945 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01271912 0,06892387 ! enteric nervous system development GO:0048484 8 5 0,000 0,01271912 0,06876898 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01271912 0,06861479 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01271912 0,06846129 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01271912 0,06830848 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01271912 0,06815634 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01271912 0,06800488 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01271912 0,0678541 ! plasminogen activation GO:0031639 5 5 0,000 0,01271912 0,06770398 ! B cell homeostasis GO:0001782 13 5 0,000 0,01271912 0,06755452 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01271912 0,06740572 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01271912 0,06725758 ! metaphase GO:0051323 8 5 0,000 0,01271912 0,06711008 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01271912 0,06696323 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01271912 0,06681703 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01271912 0,06667146 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01271912 0,06652652 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01271912 0,06638221 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01271912 0,06623852 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01271912 0,06609546 ! response to redox state GO:0051775 5 5 0,000 0,01271912 0,06595301 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01271912 0,06581118 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01271912 0,06566995 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01271912 0,06552933 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01271912 0,06538931 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01271912 0,06524989 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01271912 0,06511106 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01271912 0,06497282 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01271912 0,06483517 ! striatum development GO:0021756 9 5 0,000 0,01271912 0,06469809 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01271912 0,0645616 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01271912 0,06442568 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01271912 0,06429033 ! glial cell migration GO:0008347 11 5 0,000 0,01271912 0,06415555 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01271912 0,06402134 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01271912 0,06388768 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01271912 0,06375458 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01271912 0,06362203 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01271912 0,06349004 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01271912 0,06335859 ! neuroprotection GO:0043526 6 5 0,000 0,01271912 0,06322768 ! neural plate development GO:0001840 8 5 0,000 0,01271912 0,06309732 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01271912 0,06296749 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01271912 0,06283819 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01271912 0,06270942 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01271912 0,06258118 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01271912 0,06245347 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01271912 0,06232627 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01271912 0,06219959 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01271912 0,06207342 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01271912 0,06194777 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01271912 0,06182262 ! spindle assembly GO:0051225 6 5 0,000 0,01271912 0,06169798 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01271912 0,06157384 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01271912 0,0614502 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01271912 0,06132705 ! drug metabolic process GO:0017144 6 5 0,000 0,01271912 0,0612044 ! stem cell division GO:0017145 11 5 0,000 0,01271912 0,06108223 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01271912 0,06096055 ! organ regeneration GO:0031100 7 5 0,000 0,01271912 0,06083936 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01271912 0,06071865 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01271912 0,06059841 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01271912 0,06047865 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01281309 0,06080534 ! viral reproduction GO:0016032 134 68 1,000 0,01317972 0,06242204 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,01355088 0,06405388 ! B cell activation GO:0042113 160 71 1,000 0,01430674 0,06749416 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01469139 0,06917315 ! axon guidance GO:0007411 139 73 1,000 0,01508048 0,07086647 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01524371 0,07149391 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01524371 0,07135482 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01524371 0,07121626 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01524371 0,07107825 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01524371 0,07094077 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01524371 0,07080381 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01524371 0,07066739 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01524371 0,07053149 ! sleep GO:0030431 13 6 0,000 0,01524371 0,07039611 ! response to oxygen radical GO:0000305 11 6 0,000 0,01524371 0,07026126 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01524371 0,07012691 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01524371 0,06999308 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01524371 0,06985976 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01524371 0,06972695 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01524371 0,06959464 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01524371 0,06946283 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01524371 0,06933152 ! forebrain regionalization GO:0021871 8 6 0,000 0,01524371 0,06920071 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01524371 0,06907039 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01524371 0,06894056 ! response to zinc ion GO:0010043 9 6 0,000 0,01524371 0,06881121 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01524371 0,06868235 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01524371 0,06855397 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01524371 0,06842607 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01524371 0,06829865 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01524371 0,0681717 ! malate metabolic process GO:0006108 11 6 0,000 0,01524371 0,06804522 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01524371 0,06791921 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01524371 0,06779367 ! protein refolding GO:0042026 15 6 0,000 0,01524371 0,06766859 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01524371 0,06754397 ! opsonization GO:0008228 8 6 0,000 0,01524371 0,06741981 ! mating behavior GO:0007617 7 6 0,000 0,01524371 0,0672961 ! neuron remodeling GO:0016322 15 6 0,000 0,01524371 0,06717285 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01524371 0,06705005 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01524371 0,06692769 ! equilibrioception GO:0050957 14 6 0,000 0,01524371 0,06680578 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01524371 0,06668432 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01524371 0,0665633 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01524371 0,06644271 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01524371 0,06632256 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01524371 0,06620284 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01524371 0,06608356 ! toxin metabolic process GO:0009404 11 6 0,000 0,01524371 0,0659647 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01524371 0,06584628 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01524371 0,06572827 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01524371 0,06561069 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01524371 0,06549353 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01524371 0,06537678 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01524371 0,06526045 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01524371 0,06514454 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01524371 0,06502903 ! thymic T cell selection GO:0045061 12 6 0,000 0,01524371 0,06491394 ! protein lipoylation GO:0009249 10 6 0,000 0,01524371 0,06479925 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01524371 0,06468497 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01524371 0,06457108 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01524371 0,0644576 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01524371 0,06434452 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01524371 0,06423183 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01524371 0,06411954 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01524371 0,06400764 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01524371 0,06389612 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01524371 0,063785 ! hyperosmotic response GO:0006972 9 6 0,000 0,01524371 0,06367426 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01524371 0,06356391 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01524371 0,06345394 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01524371 0,06334434 ! urea metabolic process GO:0019627 7 6 0,000 0,01524371 0,06323513 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01524371 0,06312629 ! neutrophil activation GO:0042119 8 6 0,000 0,01524371 0,06301783 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01524371 0,06290974 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01524371 0,06280201 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01524371 0,06269466 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01524371 0,06258767 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01524371 0,06248105 ! neuron apoptosis GO:0051402 9 6 0,000 0,01524371 0,06237479 ! nucleoside salvage GO:0043174 9 6 0,000 0,01524371 0,06226889 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01524371 0,06216335 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01524371 0,06205817 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01524371 0,06195334 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01524371 0,06184886 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01524371 0,06174474 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01524371 0,06164097 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01524371 0,06153754 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01524371 0,06143447 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01524371 0,06133173 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01524371 0,06122934 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01524371 0,06112729 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01524371 0,06102558 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01524371 0,06092421 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01524371 0,06082318 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01524371 0,06072248 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01524371 0,06062211 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01524371 0,06052207 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01524371 0,06042237 ! neural nucleus development GO:0048857 14 6 0,000 0,01524371 0,06032299 ! response to UV-C GO:0010225 11 6 0,000 0,01524371 0,06022393 ! astrocyte development GO:0014002 15 6 0,000 0,01524371 0,06012521 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01524371 0,0600268 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01524371 0,05992872 ! interaction with symbiont GO:0051702 13 6 0,000 0,01524371 0,05983096 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01524371 0,05973351 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01524371 0,05963638 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01524371 0,05953957 ! response to copper ion GO:0046688 10 6 0,000 0,01524371 0,05944307 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01524371 0,05934689 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01524371 0,05925101 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01524371 0,05915544 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01524371 0,05906019 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01524371 0,05896523 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01524371 0,05887059 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01524371 0,05877624 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01524371 0,0586822 ! hair follicle maturation GO:0048820 7 6 0,000 0,01524371 0,05858846 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01524371 0,05849502 ! Schwann cell development GO:0014044 15 6 0,000 0,01524371 0,05840187 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01524371 0,05830902 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01524371 0,05821647 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01524371 0,05812421 ! subpallium development GO:0021544 10 6 0,000 0,01524371 0,05803224 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01524371 0,05794056 ! histone ubiquitination GO:0016574 8 6 0,000 0,01524371 0,05784917 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01524371 0,05775807 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01524371 0,05766726 ! G2 phase GO:0051319 16 6 0,000 0,01524371 0,05757673 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01524371 0,05748648 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01524371 0,05739652 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01524371 0,05730684 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01524371 0,05721743 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01524371 0,05712831 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01524371 0,05703946 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01524371 0,05695089 ! receptor internalization GO:0031623 10 6 0,000 0,01524371 0,0568626 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01524371 0,05677458 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01524371 0,05668682 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01524371 0,05659935 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01524371 0,05651213 ! protein deubiquitination GO:0016579 14 6 0,000 0,01524371 0,05642519 ! protein destabilization GO:0031648 9 6 0,000 0,01524371 0,05633852 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01524371 0,05625211 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01524371 0,05616597 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01524371 0,05608009 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01524371 0,05599447 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01524371 0,05590911 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01524371 0,05582401 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01524371 0,05573917 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01524371 0,05565459 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01524371 0,05557027 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01524371 0,0554862 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01524371 0,05540238 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01524371 0,05531882 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01524371 0,05523551 ! catecholamine transport GO:0051937 9 6 0,000 0,01524371 0,05515244 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01524371 0,05506963 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01524371 0,05498707 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01524371 0,05490475 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01524371 0,05482268 ! maternal placenta development GO:0001893 12 6 0,000 0,01524371 0,05474086 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01524371 0,05465928 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01524371 0,05457794 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01524371 0,05449684 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01524371 0,05441599 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01524371 0,05433537 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01524371 0,05425499 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01524371 0,05417485 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01547399 0,05491211 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,01547399 0,05483124 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 1,000 0,01587189 0,05615848 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01668078 0,05893387 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01750696 0,06176211 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,01750696 0,06167168 ! tRNA transcription GO:0009304 14 7 0,000 0,01776194 0,06247839 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01776194 0,06238719 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01776194 0,06229624 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01776194 0,06220556 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01776194 0,06211515 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01776194 0,062025 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01776194 0,0619351 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01776194 0,06184547 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01776194 0,0617561 ! prostate gland development GO:0030850 13 7 0,000 0,01776194 0,06166699 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01776194 0,06157813 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01776194 0,06148953 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01776194 0,06140118 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01776194 0,06131309 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01776194 0,06122525 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01776194 0,06113766 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01776194 0,06105032 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01776194 0,06096323 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01776194 0,06087638 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01776194 0,06078979 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01776194 0,06070344 ! glycolipid transport GO:0046836 10 7 0,000 0,01776194 0,06061734 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01776194 0,06053148 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01776194 0,06044586 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01776194 0,06036048 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01776194 0,06027535 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01776194 0,06019045 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01776194 0,0601058 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01776194 0,06002138 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01776194 0,0599372 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01776194 0,05985325 ! mRNA stabilization GO:0048255 18 7 0,000 0,01776194 0,05976954 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01776194 0,05968606 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01776194 0,05960282 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01776194 0,05951981 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01776194 0,05943703 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01776194 0,05935447 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01776194 0,05927215 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01776194 0,05919006 ! lipoprotein transport GO:0042953 14 7 0,000 0,01776194 0,05910819 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01776194 0,05902655 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01776194 0,05894513 ! rhythmic behavior GO:0007622 15 7 0,000 0,01776194 0,05886394 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01776194 0,05878297 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01776194 0,05870223 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01776194 0,0586217 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01776194 0,0585414 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01776194 0,05846132 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01776194 0,05838145 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01776194 0,0583018 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01776194 0,05822237 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01776194 0,05814316 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01776194 0,05806416 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01776194 0,05798538 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01776194 0,0579068 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01776194 0,05782845 ! spinal cord patterning GO:0021511 13 7 0,000 0,01776194 0,0577503 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01776194 0,05767236 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01776194 0,05759464 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01776194 0,05751712 ! adrenal gland development GO:0030325 17 7 0,000 0,01776194 0,05743981 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01776194 0,05736271 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01776194 0,05728582 ! ovulation GO:0030728 9 7 0,000 0,01776194 0,05720913 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01776194 0,05713265 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01776194 0,05705637 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01776194 0,0569803 ! microtubule nucleation GO:0007020 20 7 0,000 0,01776194 0,05690442 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01776194 0,05682875 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01776194 0,05675328 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01776194 0,05667801 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01776194 0,05660294 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01776194 0,05652807 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01776194 0,0564534 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01776194 0,05637892 ! galactose metabolic process GO:0006012 13 7 0,000 0,01776194 0,05630464 ! vesicle fusion GO:0006906 17 7 0,000 0,01776194 0,05623056 ! response to dietary excess GO:0002021 8 7 0,000 0,01776194 0,05615666 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01776194 0,05608297 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01776194 0,05600947 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01776194 0,05593615 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01776194 0,05586304 ! purine salvage GO:0043101 10 7 0,000 0,01776194 0,05579011 ! nucleoside transport GO:0015858 8 7 0,000 0,01776194 0,05571737 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01776194 0,05564482 ! parturition GO:0007567 14 7 0,000 0,01776194 0,05557246 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01776194 0,05550029 ! rRNA modification GO:0000154 14 7 0,000 0,01776194 0,0554283 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01776194 0,0553565 ! spindle checkpoint GO:0031577 15 7 0,000 0,01776194 0,05528489 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01776194 0,05521346 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01776194 0,05514222 ! macrophage differentiation GO:0030225 11 7 0,000 0,01776194 0,05507116 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01776194 0,05500029 ! centrosome duplication GO:0051298 13 7 0,000 0,01776194 0,05492959 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01776194 0,05485908 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01776194 0,05478875 ! fibrinolysis GO:0042730 10 7 0,000 0,01776194 0,05471859 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01776194 0,05464862 ! eating behavior GO:0042755 7 7 0,000 0,01776194 0,05457883 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01776194 0,05450921 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01776194 0,05443977 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01776194 0,05437051 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01776194 0,05430143 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01776194 0,05423252 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01776194 0,05416378 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01776194 0,05409522 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01776194 0,05402683 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01776194 0,05395861 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01776194 0,05389057 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01776194 0,0538227 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01776194 0,053755 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01776194 0,05368746 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01776194 0,0536201 ! regulation of meiosis GO:0040020 12 7 0,000 0,01776194 0,05355291 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01776194 0,05348588 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01776194 0,05341903 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01776194 0,05335234 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01776194 0,05328581 ! transcription termination GO:0006353 13 7 0,000 0,01776194 0,05321945 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01776194 0,05315326 ! anaphase GO:0051322 17 7 0,000 0,01776194 0,05308723 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01776194 0,05302137 ! axonal fasciculation GO:0007413 18 7 0,000 0,01776194 0,05295567 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01776194 0,05289013 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01776194 0,05282475 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01776194 0,05275953 ! diuresis GO:0030146 12 7 0,000 0,01776194 0,05269448 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01776194 0,05262958 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01776194 0,05256485 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01776194 0,05250027 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01776194 0,05243586 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01776194 0,0523716 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01776194 0,05230749 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01776194 0,05224355 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01776194 0,05217976 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01776194 0,05211612 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01776194 0,05205265 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01776194 0,05198932 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01776194 0,05192615 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01776194 0,05186313 ! lymph node development GO:0048535 10 7 0,000 0,01776194 0,05180027 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01776194 0,05173756 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01776194 0,051675 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01776194 0,05161259 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01776194 0,05155033 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01776194 0,05148822 ! adult feeding behavior GO:0008343 9 7 0,000 0,01776194 0,05142626 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01776194 0,05136445 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01776194 0,05130279 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01776194 0,05124127 ! muscle adaptation GO:0043500 14 7 0,000 0,01776194 0,05117991 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01776194 0,05111869 ! retina homeostasis GO:0001895 12 7 0,000 0,01776194 0,05105761 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01776194 0,05099668 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01776194 0,0509359 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01776194 0,05087526 ! protein prenylation GO:0018342 18 7 0,000 0,01776194 0,05081477 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01776194 0,05075442 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01776194 0,05069421 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01776194 0,05063415 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,01792648 0,05104272 ! protein import into nucleus GO:0006606 158 80 1,000 0,01792648 0,05098239 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01835024 0,05212594 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 1,000 0,01835024 0,05206447 ! response to drug GO:0042493 143 82 1,000 0,01877823 0,05321603 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,01877823 0,05315343 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,01877823 0,05309097 ! regulation of lyase activity GO:0051339 160 83 1,000 0,01921042 0,05424913 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,01964678 0,05541637 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,01964678 0,05535148 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02008731 0,05652638 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02027381 0,05698455 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02027381 0,05691806 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02027381 0,05685172 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02027381 0,05678554 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02027381 0,05671951 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02027381 0,05665363 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02027381 0,05658791 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02027381 0,05652233 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02027381 0,05645692 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02027381 0,05639165 ! meiotic prophase I GO:0007128 13 8 0,000 0,02027381 0,05632653 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02027381 0,05626156 ! oligopeptide transport GO:0006857 15 8 0,000 0,02027381 0,05619675 ! UTP metabolic process GO:0046051 8 8 0,000 0,02027381 0,05613208 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02027381 0,05606756 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02027381 0,05600319 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02027381 0,05593896 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02027381 0,05587489 ! succinate metabolic process GO:0006105 14 8 0,000 0,02027381 0,05581096 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02027381 0,05574717 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02027381 0,05568353 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02027381 0,05562004 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02027381 0,05555669 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02027381 0,05549349 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02027381 0,05543043 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02027381 0,05536751 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02027381 0,05530473 ! reflex GO:0060004 16 8 0,000 0,02027381 0,0552421 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02027381 0,05517961 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02027381 0,05511726 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02027381 0,05505505 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02027381 0,05499298 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02027381 0,05493105 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02027381 0,05486926 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02027381 0,05480761 ! pigment granule organization GO:0048753 16 8 0,000 0,02027381 0,0547461 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02027381 0,05468473 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02027381 0,05462349 ! histidine metabolic process GO:0006547 16 8 0,000 0,02027381 0,05456239 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02027381 0,05450142 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02027381 0,0544406 ! glycine catabolic process GO:0006546 13 8 0,000 0,02027381 0,05437991 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02027381 0,05431935 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02027381 0,05425893 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02027381 0,05419864 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02027381 0,05413849 ! melanin metabolic process GO:0006582 15 8 0,000 0,02027381 0,05407846 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02027381 0,05401858 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02027381 0,05395882 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02027381 0,0538992 ! macrophage activation GO:0042116 12 8 0,000 0,02027381 0,05383971 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02027381 0,05378035 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02027381 0,05372112 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02027381 0,05366202 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02027381 0,05360305 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02027381 0,05354421 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02027381 0,0534855 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02027381 0,05342692 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02027381 0,05336846 ! osteoblast development GO:0002076 16 8 0,000 0,02027381 0,05331014 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02027381 0,05325194 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02027381 0,05319387 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02027381 0,05313592 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02027381 0,0530781 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02027381 0,05302041 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02027381 0,05296284 ! response to UV-B GO:0010224 16 8 0,000 0,02027381 0,0529054 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02027381 0,05284808 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02027381 0,05279088 ! intermediate filament organization GO:0045109 12 8 0,000 0,02027381 0,05273381 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02027381 0,05267686 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02027381 0,05262004 ! cellular extravasation GO:0045123 12 8 0,000 0,02027381 0,05256334 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02027381 0,05250675 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02027381 0,0524503 ! response to antibiotic GO:0046677 11 8 0,000 0,02027381 0,05239396 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02027381 0,05233774 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02027381 0,05228165 ! DNA topological change GO:0006265 12 8 0,000 0,02027381 0,05222567 ! response to tropane GO:0014073 15 8 0,000 0,02027381 0,05216981 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02027381 0,05211408 ! melanosome transport GO:0032402 13 8 0,000 0,02027381 0,05205846 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02027381 0,05200296 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02027381 0,05194758 ! mast cell activation GO:0045576 14 8 0,000 0,02027381 0,05189231 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02027381 0,05183717 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02027381 0,05178214 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02027381 0,05172723 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02027381 0,05167243 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02027381 0,05161775 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02027381 0,05156319 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02027381 0,05150874 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02027381 0,0514544 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02027381 0,05140018 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02027381 0,05134608 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02027381 0,05129209 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02027381 0,05123821 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02027381 0,05118444 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02027381 0,05113079 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02027381 0,05107725 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02027381 0,05102382 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02027381 0,05097051 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02027381 0,0509173 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02027381 0,05086421 ! hormone catabolic process GO:0042447 17 8 0,000 0,02027381 0,05081122 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02027381 0,05075835 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02027381 0,05070559 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02027381 0,05065293 ! ATP catabolic process GO:0006200 11 8 0,000 0,02027381 0,05060039 ! blastocyst growth GO:0001832 19 8 0,000 0,02027381 0,05054795 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02027381 0,05049563 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02027381 0,05044341 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02027381 0,0503913 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02027381 0,05033929 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02027381 0,0502874 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02027381 0,05023561 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02027381 0,05018392 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02027381 0,05013235 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02027381 0,05008088 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02027381 0,05002951 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02027381 0,04997825 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02027381 0,0499271 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02027381 0,04987605 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02027381 0,0498251 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02027381 0,04977426 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02027381 0,04972352 ! mitochondrion organization GO:0007005 148 86 1,000 0,02053196 0,05030539 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,02098072 0,05135261 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,02098072 0,05130042 ! regulation of DNA binding GO:0051101 155 88 1,000 0,02143357 0,05235448 ! gland development GO:0048732 206 88 1,000 0,02143357 0,05230138 ! regulation of neurological system process GO:0031644 148 88 1,000 0,02143357 0,05224839 ! ossification GO:0001503 188 90 1,000 0,02235142 0,05443068 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,02235142 0,05437564 ! axon extension GO:0048675 15 9 0,000 0,02277933 0,05536068 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02277933 0,05530482 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02277933 0,05524907 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02277933 0,05519343 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02277933 0,0551379 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02277933 0,05508249 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02277933 0,05502718 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02277933 0,05497199 ! phosphate transport GO:0006817 19 9 0,000 0,02277933 0,05491691 ! reproductive behavior GO:0019098 19 9 0,000 0,02277933 0,05486194 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02277933 0,05480707 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02277933 0,05475232 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02277933 0,05469768 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02277933 0,05464314 ! GTP metabolic process GO:0046039 9 9 0,000 0,02277933 0,05458872 ! RNA methylation GO:0001510 15 9 0,000 0,02277933 0,0545344 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02277933 0,05448019 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02277933 0,05442609 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02277933 0,0543721 ! artery development GO:0060840 24 9 0,000 0,02277933 0,05431821 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02277933 0,05426443 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02277933 0,05421076 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02277933 0,05415719 ! chemosensory behavior GO:0007635 20 9 0,000 0,02277933 0,05410372 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02277933 0,05405037 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02277933 0,05399712 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02277933 0,05394397 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02277933 0,05389093 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02277933 0,05383799 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02277933 0,05378516 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02277933 0,05373242 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02277933 0,0536798 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02277933 0,05362727 ! protein targeting to ER GO:0045047 22 9 0,000 0,02277933 0,05357485 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02277933 0,05352253 ! T cell selection GO:0045058 23 9 0,000 0,02277933 0,05347032 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02277933 0,0534182 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02277933 0,05336619 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02277933 0,05331427 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02277933 0,05326246 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02277933 0,05321075 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02277933 0,05315914 ! mannose metabolic process GO:0006013 13 9 0,000 0,02277933 0,05310763 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02277933 0,05305622 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02277933 0,05300491 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02277933 0,05295369 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02277933 0,05290258 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02277933 0,05285157 ! ruffle organization GO:0031529 15 9 0,000 0,02277933 0,05280065 ! retinol metabolic process GO:0042572 18 9 0,000 0,02277933 0,05274983 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02277933 0,05269911 ! behavioral fear response GO:0001662 22 9 0,000 0,02277933 0,05264849 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02277933 0,05259796 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02277933 0,05254753 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02277933 0,0524972 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02277933 0,05244696 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02277933 0,05239682 ! segment specification GO:0007379 13 9 0,000 0,02277933 0,05234677 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02277933 0,05229683 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02277933 0,05224697 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02277933 0,05219721 ! response to amine stimulus GO:0014075 13 9 0,000 0,02277933 0,05214755 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02277933 0,05209798 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02277933 0,0520485 ! erythrocyte development GO:0048821 15 9 0,000 0,02277933 0,05199912 ! gas homeostasis GO:0033483 16 9 0,000 0,02277933 0,05194983 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02277933 0,05190064 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02277933 0,05185154 ! renal water homeostasis GO:0003091 14 9 0,000 0,02277933 0,05180253 ! postreplication repair GO:0006301 22 9 0,000 0,02277933 0,05175361 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02277933 0,05170479 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02277933 0,05165605 ! icosanoid secretion GO:0032309 15 9 0,000 0,02277933 0,05160741 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02277933 0,05155886 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02277933 0,05151041 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02277933 0,05146204 ! regulation of cell division GO:0051302 15 9 0,000 0,02277933 0,05141376 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02277933 0,05136558 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02277933 0,05131748 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02277933 0,05126948 ! sterol catabolic process GO:0016127 11 9 0,000 0,02277933 0,05122156 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02277933 0,05117374 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02277933 0,051126 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02277933 0,05107835 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02277933 0,05103079 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02277933 0,05098332 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02277933 0,05093594 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02277933 0,05088865 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02277933 0,05084144 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02277933 0,05079432 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02277933 0,05074729 ! purine base metabolic process GO:0006144 21 9 0,000 0,02277933 0,05070035 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02277933 0,05065349 ! pigment granule transport GO:0051904 17 9 0,000 0,02277933 0,05060672 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02277933 0,05056003 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02277933 0,05051343 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02277933 0,05046692 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02277933 0,05042049 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02277933 0,05037415 ! mitochondrion localization GO:0051646 15 9 0,000 0,02277933 0,05032789 ! bone development GO:0060348 189 91 1,000 0,02281638 0,05036349 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,02375825 0,05239445 ! regulation of membrane potential GO:0042391 164 93 1,000 0,02375825 0,05234647 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02423511 0,05334829 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02527853 0,05559429 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02527853 0,05554352 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02527853 0,05549284 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02527853 0,05544226 ! synapsis GO:0007129 13 10 0,000 0,02527853 0,05539176 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02527853 0,05534136 ! N-glycan processing GO:0006491 20 10 0,000 0,02527853 0,05529105 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02527853 0,05524083 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02527853 0,0551907 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02527853 0,05514067 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02527853 0,05509072 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02527853 0,05504086 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02527853 0,0549911 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02527853 0,05494142 ! androgen metabolic process GO:0008209 17 10 0,000 0,02527853 0,05489184 ! phospholipid efflux GO:0033700 16 10 0,000 0,02527853 0,05484234 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02527853 0,05479293 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02527853 0,05474361 ! lung alveolus development GO:0048286 26 10 0,000 0,02527853 0,05469438 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02527853 0,05464524 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02527853 0,05459619 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02527853 0,05454722 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02527853 0,05449835 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02527853 0,05444956 ! endoderm development GO:0007492 16 10 0,000 0,02527853 0,05440085 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02527853 0,05435224 ! arginine catabolic process GO:0006527 13 10 0,000 0,02527853 0,05430371 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02527853 0,05425527 ! proline metabolic process GO:0006560 13 10 0,000 0,02527853 0,05420691 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02527853 0,05415864 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02527853 0,05411046 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02527853 0,05406236 ! V(D)J recombination GO:0033151 28 10 0,000 0,02527853 0,05401435 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02527853 0,05396642 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02527853 0,05391858 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02527853 0,05387082 ! B cell proliferation GO:0042100 18 10 0,000 0,02527853 0,05382315 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02527853 0,05377556 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02527853 0,05372805 ! multicellular organism growth GO:0035264 18 10 0,000 0,02527853 0,05368063 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02527853 0,05363329 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02527853 0,05358604 ! epithelial cell development GO:0002064 20 10 0,000 0,02527853 0,05353887 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02527853 0,05349178 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02527853 0,05344478 ! macroautophagy GO:0016236 17 10 0,000 0,02527853 0,05339785 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02527853 0,05335101 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02527853 0,05330425 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02527853 0,05325758 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02527853 0,05321098 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02527853 0,05316447 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02527853 0,05311804 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02527853 0,05307169 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02527853 0,05302542 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02527853 0,05297923 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02527853 0,05293312 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02527853 0,05288709 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02527853 0,05284114 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02527853 0,05279527 ! response to dsRNA GO:0043331 20 10 0,000 0,02527853 0,05274948 ! DNA ligation GO:0006266 19 10 0,000 0,02527853 0,05270377 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02527853 0,05265814 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02527853 0,05261259 ! melanosome localization GO:0032400 16 10 0,000 0,02527853 0,05256712 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02527853 0,05252172 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02527853 0,05247641 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02527853 0,05243117 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02527853 0,05238601 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02527853 0,05234092 ! mRNA cleavage GO:0006379 17 10 0,000 0,02527853 0,05229592 ! protein sumoylation GO:0016925 15 10 0,000 0,02527853 0,05225099 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02527853 0,05220614 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02527853 0,05216137 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02527853 0,05211667 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02527853 0,05207205 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02527853 0,05202751 ! salivary gland development GO:0007431 27 10 0,000 0,02527853 0,05198304 ! prophase GO:0051324 15 10 0,000 0,02527853 0,05193865 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02527853 0,05189433 ! apical protein localization GO:0045176 15 10 0,000 0,02527853 0,05185009 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02527853 0,05180592 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02527853 0,05176183 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02527853 0,05171782 ! midbrain development GO:0030901 13 10 0,000 0,02527853 0,05167388 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02527853 0,05163001 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02527853 0,05158622 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02527853 0,0515425 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02527853 0,05149886 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02527853 0,05145529 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02527853 0,0514118 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02527853 0,05136837 ! detection of calcium ion GO:0005513 23 10 0,000 0,02527853 0,05132503 ! oocyte development GO:0048599 17 10 0,000 0,02527853 0,05128175 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02527853 0,05123855 ! blastocyst formation GO:0001825 17 10 0,000 0,02527853 0,05119542 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02527853 0,05115236 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02527853 0,05110937 ! activation of innate immune response GO:0002218 12 10 0,000 0,02527853 0,05106646 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02527853 0,05102362 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02527853 0,05098085 ! response to nicotine GO:0035094 20 10 0,000 0,02527853 0,05093815 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02527853 0,05089553 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02527853 0,05085297 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02527853 0,05081049 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,02667785 0,05357838 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,02667785 0,0535337 GO:0060538|skeletal muscle organ development, ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02777143 0,05568171 ! respiratory burst GO:0045730 17 11 0,000 0,02777143 0,05563535 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02777143 0,05558907 ! neuron fate specification GO:0048665 17 11 0,000 0,02777143 0,05554286 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02777143 0,05549673 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02777143 0,05545067 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02777143 0,05540469 ! thyroid gland development GO:0030878 26 11 0,000 0,02777143 0,05535879 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02777143 0,05531296 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02777143 0,05526721 ! response to pain GO:0048265 24 11 0,000 0,02777143 0,05522153 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02777143 0,05517593 ! T cell proliferation GO:0042098 26 11 0,000 0,02777143 0,05513041 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02777143 0,05508496 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02777143 0,05503959 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02777143 0,05499429 ! bone resorption GO:0045453 16 11 0,000 0,02777143 0,05494906 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02777143 0,05490391 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02777143 0,05485883 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02777143 0,05481383 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02777143 0,0547689 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02777143 0,05472404 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02777143 0,05467926 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02777143 0,05463455 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02777143 0,05458992 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02777143 0,05454535 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02777143 0,05450086 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,02777143 0,05445644 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02777143 0,0544121 ! UV protection GO:0009650 19 11 0,000 0,02777143 0,05436783 ! adult heart development GO:0007512 14 11 0,000 0,02777143 0,05432362 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02777143 0,05427949 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02777143 0,05423544 ! temperature homeostasis GO:0001659 17 11 0,000 0,02777143 0,05419145 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02777143 0,05414753 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02777143 0,05410369 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02777143 0,05405992 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02777143 0,05401621 ! regulation of organ growth GO:0046620 13 11 0,000 0,02777143 0,05397258 ! pigment granule localization GO:0051875 20 11 0,000 0,02777143 0,05392902 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02777143 0,05388553 ! vasoconstriction GO:0042310 18 11 0,000 0,02777143 0,05384211 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02777143 0,05379876 ! embryonic axis specification GO:0000578 18 11 0,000 0,02777143 0,05375548 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02777143 0,05371226 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02777143 0,05366912 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02777143 0,05362605 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02777143 0,05358305 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02777143 0,05354011 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02777143 0,05349724 ! zymogen activation GO:0031638 15 11 0,000 0,02777143 0,05345445 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02777143 0,05341172 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02777143 0,05336906 ! nucleosome positioning GO:0016584 15 11 0,000 0,02777143 0,05332646 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02777143 0,05328394 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02777143 0,05324148 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02777143 0,05319909 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02777143 0,05315677 ! acid secretion GO:0046717 18 11 0,000 0,02777143 0,05311451 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02777143 0,05307233 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02777143 0,0530302 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02777143 0,05298815 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02777143 0,05294616 ! oocyte differentiation GO:0009994 18 11 0,000 0,02777143 0,05290424 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02777143 0,05286239 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02777143 0,0528206 ! cholesterol efflux GO:0033344 19 11 0,000 0,02777143 0,05277888 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02777143 0,05273722 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02777143 0,05269563 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02777143 0,0526541 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02777143 0,05261264 ! embryonic gut development GO:0048566 15 11 0,000 0,02777143 0,05257125 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02777143 0,05252992 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02777143 0,05248865 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02777143 0,05244745 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02777143 0,05240632 ! defense response to fungus GO:0050832 13 11 0,000 0,02777143 0,05236525 ! developmental induction GO:0031128 19 11 0,000 0,02777143 0,05232424 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02777143 0,0522833 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02777143 0,05224242 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02777143 0,05220161 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02777143 0,05216086 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02777143 0,05212017 ! nucleus localization GO:0051647 19 11 0,000 0,02777143 0,05207955 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02777143 0,05203899 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03025803 0,05665433 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03025803 0,05661028 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03025803 0,05656629 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03025803 0,05652237 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03025803 0,05647852 ! cartilage condensation GO:0001502 20 12 0,000 0,03025803 0,05643474 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03025803 0,05639103 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03025803 0,05634738 ! protein complex disassembly GO:0043241 27 12 0,000 0,03025803 0,0563038 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03025803 0,05626029 ! hippocampus development GO:0021766 26 12 0,000 0,03025803 0,05621685 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03025803 0,05617347 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03025803 0,05613016 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03025803 0,05608692 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03025803 0,05604374 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03025803 0,05600063 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03025803 0,05595759 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03025803 0,05591461 ! drug transport GO:0015893 16 12 0,000 0,03025803 0,05587169 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03025803 0,05582885 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03025803 0,05578607 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03025803 0,05574335 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03025803 0,0557007 ! focal adhesion formation GO:0048041 35 12 0,000 0,03025803 0,05565812 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03025803 0,0556156 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03025803 0,05557314 ! forebrain cell migration GO:0021885 21 12 0,000 0,03025803 0,05553075 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03025803 0,05548843 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03025803 0,05544617 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03025803 0,05540397 ! entry into host cell GO:0030260 32 12 0,000 0,03025803 0,05536184 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03025803 0,05531977 ! monoamine transport GO:0015844 18 12 0,000 0,03025803 0,05527777 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03025803 0,05523583 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03025803 0,05519395 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03025803 0,05515214 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03025803 0,05511038 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03025803 0,0550687 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03025803 0,05502707 ! protein homotetramerization GO:0051289 21 12 0,000 0,03025803 0,05498551 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03025803 0,05494401 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03025803 0,05490258 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03025803 0,0548612 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03025803 0,05481989 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03025803 0,05477864 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03025803 0,05473746 ! cranial nerve development GO:0021545 20 12 0,000 0,03025803 0,05469633 ! fucose catabolic process GO:0019317 22 12 0,000 0,03025803 0,05465527 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03025803 0,05461427 ! histone acetylation GO:0016573 26 12 0,000 0,03025803 0,05457333 ! histone methylation GO:0016571 26 12 0,000 0,03025803 0,05453245 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03025803 0,05449163 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03025803 0,05445087 ! gland morphogenesis GO:0022612 29 12 0,000 0,03025803 0,05441018 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03025803 0,05436954 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03025803 0,05432897 ! T cell homeostasis GO:0043029 25 12 0,000 0,03025803 0,05428846 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03025803 0,054248 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03025803 0,05420761 ! spleen development GO:0048536 22 12 0,000 0,03025803 0,05416728 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03025803 0,054127 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03025803 0,05408679 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03025803 0,05404664 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03025803 0,05400654 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03025803 0,05396651 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03025803 0,05392653 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03025803 0,05388662 ! response to cold GO:0009409 17 12 0,000 0,03025803 0,05384676 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03025803 0,05380696 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03025803 0,05376722 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03273835 0,05813172 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03273835 0,05808885 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03273835 0,05804604 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03273835 0,0580033 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03273835 0,05796062 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03273835 0,057918 ! lipid localization GO:0010876 28 13 0,000 0,03273835 0,05787544 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03273835 0,05783295 ! organelle fusion GO:0048284 32 13 0,000 0,03273835 0,05779052 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03273835 0,05774815 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03273835 0,05770584 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03273835 0,0576636 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03273835 0,05762142 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03273835 0,0575793 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03273835 0,05753724 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03273835 0,05749524 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03273835 0,0574533 ! methionine metabolic process GO:0006555 27 13 0,000 0,03273835 0,05741143 ! plasma membrane organization GO:0007009 24 13 0,000 0,03273835 0,05736961 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03273835 0,05732786 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03273835 0,05728616 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03273835 0,05724453 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03273835 0,05720296 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03273835 0,05716145 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03273835 0,05712 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03273835 0,05707861 ! exocrine system development GO:0035272 32 13 0,000 0,03273835 0,05703727 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03273835 0,056996 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03273835 0,05695479 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03273835 0,05691364 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03273835 0,05687255 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03273835 0,05683151 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03273835 0,05679054 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03273835 0,05674962 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03273835 0,05670877 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03273835 0,05666797 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03273835 0,05662723 ! ribosome assembly GO:0042255 17 13 0,000 0,03273835 0,05658655 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03273835 0,05654593 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03273835 0,05650536 ! chromatin silencing GO:0006342 26 13 0,000 0,03273835 0,05646486 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03273835 0,05642441 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03273835 0,05638402 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03273835 0,05634369 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03273835 0,05630341 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03273835 0,0562632 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03273835 0,05622304 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03273835 0,05618294 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03273835 0,05614289 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03273835 0,0561029 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03273835 0,05606297 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03273835 0,0560231 ! embryonic placenta development GO:0001892 23 13 0,000 0,03273835 0,05598328 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03273835 0,05594352 ! insulin secretion GO:0030073 23 13 0,000 0,03273835 0,05590382 ! actin filament polymerization GO:0030041 24 13 0,000 0,03273835 0,05586417 ! acrosome reaction GO:0007340 18 13 0,000 0,03273835 0,05582458 ! rRNA transcription GO:0009303 25 14 0,000 0,03521241 0,06000076 ! lactation GO:0007595 26 14 0,000 0,03521241 0,05995829 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03521241 0,05991589 ! reproductive cellular process GO:0048610 20 14 0,000 0,03521241 0,05987355 ! tRNA modification GO:0006400 20 14 0,000 0,03521241 0,05983126 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03521241 0,05978904 ! regulation of S phase GO:0033261 23 14 0,000 0,03521241 0,05974687 ! water transport GO:0006833 21 14 0,000 0,03521241 0,05970477 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03521241 0,05966272 ! non-recombinational repair GO:0000726 25 14 0,000 0,03521241 0,05962074 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03521241 0,05957881 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03521241 0,05953694 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03521241 0,05949513 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03521241 0,05945338 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03521241 0,05941169 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03521241 0,05937005 ! palate development GO:0060021 31 14 0,000 0,03521241 0,05932848 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03521241 0,05928696 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03521241 0,0592455 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03521241 0,0592041 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03521241 0,05916276 ! arginine metabolic process GO:0006525 17 14 0,000 0,03521241 0,05912147 ! regulation of heart rate GO:0002027 24 14 0,000 0,03521241 0,05908024 ! organic alcohol transport GO:0015850 29 14 0,000 0,03521241 0,05903907 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03521241 0,05899796 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03521241 0,0589569 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03521241 0,0589159 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03521241 0,05887496 ! L-amino acid transport GO:0015807 30 14 0,000 0,03521241 0,05883408 ! bone mineralization GO:0030282 17 14 0,000 0,03521241 0,05879325 ! stem cell development GO:0048864 43 14 0,000 0,03521241 0,05875247 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03521241 0,05871176 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03521241 0,0586711 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03521241 0,0586305 ! cerebellum development GO:0021549 21 14 0,000 0,03521241 0,05858995 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03521241 0,05854946 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03521241 0,05850902 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03521241 0,05846865 ! cofactor transport GO:0051181 26 14 0,000 0,03521241 0,05842832 ! NADP metabolic process GO:0006739 24 14 0,000 0,03521241 0,05838806 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03521241 0,05834784 ! intestinal absorption GO:0050892 25 14 0,000 0,03521241 0,05830769 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03521241 0,05826758 ! oxygen transport GO:0015671 21 14 0,000 0,03521241 0,05822754 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03521241 0,05818755 ! male genitalia development GO:0030539 24 14 0,000 0,03521241 0,05814761 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03521241 0,05810773 ! regulation of axon extension GO:0030516 37 14 0,000 0,03521241 0,0580679 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03521241 0,05802813 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03768023 0,06205245 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03768023 0,06201001 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03768023 0,06196762 ! superoxide anion generation GO:0042554 20 15 0,000 0,03768023 0,06192529 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03768023 0,06188303 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03768023 0,06184081 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03768023 0,06179866 ! copper ion transport GO:0006825 20 15 0,000 0,03768023 0,06175656 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03768023 0,06171452 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03768023 0,06167254 ! sulfate transport GO:0008272 23 15 0,000 0,03768023 0,06163061 ! response to cAMP GO:0051591 22 15 0,000 0,03768023 0,06158874 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03768023 0,06154693 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03768023 0,06150518 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03768023 0,06146348 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03768023 0,06142184 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03768023 0,06138025 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03768023 0,06133872 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03768023 0,06129725 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03768023 0,06125583 ! pituitary gland development GO:0021983 29 15 0,000 0,03768023 0,06121447 ! vesicle coating GO:0006901 33 15 0,000 0,03768023 0,06117317 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03768023 0,06113192 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03768023 0,06109072 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03768023 0,06104958 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03768023 0,0610085 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03768023 0,06096747 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03768023 0,0609265 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03768023 0,06088558 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03768023 0,06084472 ! histone deacetylation GO:0016575 20 15 0,000 0,03768023 0,06080391 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03768023 0,06076316 ! tissue regeneration GO:0042246 26 15 0,000 0,03768023 0,06072246 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03768023 0,06068182 ! water homeostasis GO:0030104 27 15 0,000 0,03768023 0,06064123 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03768023 0,06060069 ! muscle maintenance GO:0046716 26 15 0,000 0,03768023 0,06056021 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03768023 0,06051978 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03768023 0,06047941 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03768023 0,06043909 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03768023 0,06039882 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03768023 0,06035861 ! cell killing GO:0001906 29 15 0,000 0,03768023 0,06031845 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03768023 0,06027835 ! detection of bacterium GO:0016045 18 15 0,000 0,03768023 0,06023829 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03768023 0,06019829 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03768023 0,06015835 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03768023 0,06011846 ! peptide hormone processing GO:0016486 23 15 0,000 0,03768023 0,06007862 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04014181 0,06396106 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04014181 0,06391873 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04014181 0,06387646 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04014181 0,06383424 ! bone remodeling GO:0046849 27 16 0,000 0,04014181 0,06379208 ! filopodium assembly GO:0046847 32 16 0,000 0,04014181 0,06374997 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04014181 0,06370792 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04014181 0,06366592 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04014181 0,06362398 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04014181 0,0635821 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04014181 0,06354027 ! startle response GO:0001964 28 16 0,000 0,04014181 0,06349849 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04014181 0,06345677 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04014181 0,0634151 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04014181 0,06337349 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04014181 0,06333194 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04014181 0,06329044 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04014181 0,06324899 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04014181 0,06320759 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04014181 0,06316626 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04014181 0,06312497 ! response to osmotic stress GO:0006970 25 16 0,000 0,04014181 0,06308374 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04014181 0,06304256 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04014181 0,06300144 ! fructose metabolic process GO:0006000 25 16 0,000 0,04014181 0,06296037 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04014181 0,06291935 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04014181 0,06287839 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04014181 0,06283748 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04014181 0,06279662 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04014181 0,06275582 ! axon cargo transport GO:0008088 43 16 0,000 0,04014181 0,06271507 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04014181 0,06267437 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04014181 0,06263373 ! DNA replication initiation GO:0006270 27 16 0,000 0,04014181 0,06259313 ! neuron recognition GO:0008038 35 16 0,000 0,04014181 0,06255259 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04014181 0,06251211 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04014181 0,06247167 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04014181 0,06243129 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04014181 0,06239096 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04014181 0,06235068 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04014181 0,06231045 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04014181 0,06227028 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04014181 0,06223016 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04014181 0,06219009 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04014181 0,06215007 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04014181 0,0621101 ! defense response to virus GO:0051607 37 16 0,000 0,04014181 0,06207018 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04259718 0,06582455 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04259718 0,0657823 ! metencephalon development GO:0022037 30 17 0,000 0,04259718 0,06574011 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04259718 0,06569796 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04259718 0,06565588 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04259718 0,06561384 ! endothelial cell migration GO:0043542 28 17 0,000 0,04259718 0,06557186 ! inositol metabolic process GO:0006020 28 17 0,000 0,04259718 0,06552994 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04259718 0,06548807 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04259718 0,06544625 ! glial cell development GO:0021782 27 17 0,000 0,04259718 0,06540448 ! limbic system development GO:0021761 36 17 0,000 0,04259718 0,06536277 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04259718 0,06532111 ! adult walking behavior GO:0007628 33 17 0,000 0,04259718 0,06527951 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04259718 0,06523795 ! heart looping GO:0001947 30 17 0,000 0,04259718 0,06519645 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04259718 0,06515501 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04259718 0,06511361 ! myoblast differentiation GO:0045445 45 17 0,000 0,04259718 0,06507227 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04259718 0,06503098 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04259718 0,06498974 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04259718 0,06494856 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04259718 0,06490742 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04259718 0,06486634 ! glycine metabolic process GO:0006544 28 17 0,000 0,04259718 0,06482532 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04259718 0,06478434 ! NAD metabolic process GO:0019674 29 17 0,000 0,04259718 0,06474341 ! membrane budding GO:0006900 37 17 0,000 0,04259718 0,06470254 ! DNA integration GO:0015074 29 17 0,000 0,04259718 0,06466172 ! regulation of protein binding GO:0043393 33 17 0,000 0,04259718 0,06462095 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04259718 0,06458023 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04259718 0,06453956 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04259718 0,06449895 ! genitalia development GO:0048806 30 17 0,000 0,04259718 0,06445838 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04259718 0,06441787 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04259718 0,0643774 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04259718 0,06433699 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04259718 0,06429663 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04259718 0,06425632 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04259718 0,06421606 ! steroid catabolic process GO:0006706 31 17 0,000 0,04259718 0,06417584 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04259718 0,06413568 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04259718 0,06409557 ! gas transport GO:0015669 25 17 0,000 0,04259718 0,06405551 ! organic cation transport GO:0015695 31 17 0,000 0,04259718 0,06401551 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04259718 0,06397555 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04259718 0,06393564 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04259718 0,06389578 ! microspike assembly GO:0030035 36 17 0,000 0,04259718 0,06385596 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04259718 0,0638162 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04259718 0,06377649 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04504635 0,06740145 ! neuron maturation GO:0042551 42 18 0,000 0,04504635 0,06735956 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04504635 0,06731772 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04504635 0,06727593 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04504635 0,0672342 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04504635 0,06719252 ! memory GO:0007613 31 18 0,000 0,04504635 0,06715088 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04504635 0,0671093 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04504635 0,06706778 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04504635 0,0670263 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04504635 0,06698487 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04504635 0,0669435 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04504635 0,06690218 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04504635 0,0668609 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04504635 0,06681968 ! response to retinoic acid GO:0032526 26 18 0,000 0,04504635 0,06677851 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04504635 0,06673739 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04504635 0,06669632 ! response to fungus GO:0009620 21 18 0,000 0,04504635 0,06665531 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04504635 0,06661434 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04504635 0,06657342 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04504635 0,06653255 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04504635 0,06649173 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04504635 0,06645097 ! vitamin transport GO:0051180 27 18 0,000 0,04504635 0,06641025 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04504635 0,06636958 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04504635 0,06632896 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04504635 0,0662884 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04504635 0,06624788 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04504635 0,06620741 ! nerve development GO:0021675 28 18 0,000 0,04504635 0,06616699 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04504635 0,06612662 ! protein secretion GO:0009306 39 19 0,000 0,04748934 0,06967034 ! positive regulation of translation GO:0045727 30 19 0,000 0,04748934 0,06962788 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04748934 0,06958548 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04748934 0,06954312 ! skin development GO:0043588 36 19 0,000 0,04748934 0,06950082 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04748934 0,06945857 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04748934 0,06941637 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04748934 0,06937423 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04748934 0,06933213 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04748934 0,06929009 ! cerebral cortex development GO:0021987 36 19 0,000 0,04748934 0,06924809 ! pigmentation during development GO:0048066 41 19 0,000 0,04748934 0,06920615 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04748934 0,06916426 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04748934 0,06912241 ! heme metabolic process GO:0042168 36 19 0,000 0,04748934 0,06908062 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04748934 0,06903888 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04748934 0,06899719 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04748934 0,06895555 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04748934 0,06891396 ! peptide cross-linking GO:0018149 37 19 0,000 0,04748934 0,06887242 ! protein export from nucleus GO:0006611 36 19 0,000 0,04748934 0,06883093 ! heart process GO:0003015 30 19 0,000 0,04748934 0,06878949 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04748934 0,06874811 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04748934 0,06870677 ! visual learning GO:0008542 36 19 0,000 0,04748934 0,06866548 ! cellular pigmentation GO:0033059 36 19 0,000 0,04748934 0,06862423 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04748934 0,06858304 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04748934 0,0685419 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04748934 0,06850081 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04748934 0,06845977 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04748934 0,06841877 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04748934 0,06837783 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04748934 0,06833693 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04748934 0,06829609 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04748934 0,06825529 ! cilium assembly GO:0042384 37 19 0,000 0,04748934 0,06821454 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04748934 0,06817384 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04992616 0,0716293 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04992616 0,07158661 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04992616 0,07154397 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04992616 0,07150139 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04992616 0,07145885 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04992616 0,07141637 ! response to vitamin GO:0033273 31 20 0,000 0,04992616 0,07137394 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04992616 0,07133155 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04992616 0,07128922 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04992616 0,07124694 ! response to alkaloid GO:0043279 38 20 0,000 0,04992616 0,0712047 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04992616 0,07116252 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04992616 0,07112039 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04992616 0,0710783 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04992616 0,07103627 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04992616 0,07099429 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04992616 0,07095235 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04992616 0,07091047 ! body fluid secretion GO:0007589 31 20 0,000 0,04992616 0,07086863 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04992616 0,07082685 ! peptide secretion GO:0002790 35 20 0,000 0,04992616 0,07078511 ! stem cell differentiation GO:0048863 53 20 0,000 0,04992616 0,07074342 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04992616 0,07070178 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04992616 0,0706602 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04992616 0,07061866 ! sensory perception of pain GO:0019233 30 20 0,000 0,04992616 0,07057716 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04992616 0,07053572 ! diencephalon development GO:0021536 34 20 0,000 0,04992616 0,07049433 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04992616 0,07045298 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04992616 0,07041168 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04992616 0,07037044 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04992616 0,07032923 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04992616 0,07028808 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04992616 0,07024698 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04992616 0,07020592 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04992616 0,07016491 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04992616 0,07012395 ! regulation of glucose import GO:0046324 29 20 0,000 0,04992616 0,07008304 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04992616 0,07004218 ! actin filament-based movement GO:0030048 43 20 0,000 0,04992616 0,07000136 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04992616 0,06996059 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04992616 0,06991987 ! negative regulation of translation GO:0017148 29 20 0,000 0,04992616 0,06987919 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04992616 0,06983857 ! regulation of cell killing GO:0031341 42 21 0,000 0,05235682 0,07319611 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05235682 0,07315361 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05235682 0,07311115 ! hormone secretion GO:0046879 38 21 0,000 0,05235682 0,07306874 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05235682 0,07302638 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05235682 0,07298407 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05235682 0,07294181 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05235682 0,0728996 ! axis specification GO:0009798 38 21 0,000 0,05235682 0,07285744 ! ovarian follicle development GO:0001541 35 21 0,000 0,05235682 0,07281532 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05235682 0,07277326 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05235682 0,07273124 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05235682 0,07268927 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05235682 0,07264735 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05235682 0,07260548 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05235682 0,07256366 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05235682 0,07252188 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05235682 0,07248016 ! cytolysis GO:0019835 24 21 0,000 0,05235682 0,07243848 ! vasodilation GO:0042311 39 21 0,000 0,05235682 0,07239684 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05235682 0,07235526 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05235682 0,07231373 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05235682 0,07227224 ! oogenesis GO:0048477 36 21 0,000 0,05235682 0,0722308 ! DNA modification GO:0006304 34 21 0,000 0,05235682 0,0721894 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05235682 0,07214806 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05235682 0,07210676 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05235682 0,07206551 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05235682 0,07202431 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05235682 0,07198315 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05235682 0,07194204 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05235682 0,07190098 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05235682 0,07185996 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05235682 0,07181899 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05235682 0,07177807 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05235682 0,07173719 ! collagen catabolic process GO:0030574 28 21 0,000 0,05235682 0,07169636 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05235682 0,07165558 ! gut development GO:0048565 39 21 0,000 0,05235682 0,07161484 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05478135 0,07488859 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05478135 0,07484606 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05478135 0,07480359 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05478135 0,07476116 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05478135 0,07471877 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05478135 0,07467644 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,05478135 0,07463416 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05478135 0,07459192 ! regeneration GO:0031099 41 22 0,000 0,05478135 0,07454973 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05478135 0,07450759 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05478135 0,07446549 ! sensory perception of taste GO:0050909 28 22 0,000 0,05478135 0,07442344 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05478135 0,07438144 ! vacuolar transport GO:0007034 36 22 0,000 0,05478135 0,07433949 ! lysosome organization GO:0007040 41 22 0,000 0,05478135 0,07429759 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05478135 0,07425573 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05478135 0,07421392 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05478135 0,07417215 ! fucose metabolic process GO:0006004 39 22 0,000 0,05478135 0,07413044 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05478135 0,07408877 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05478135 0,07404715 ! ureteric bud development GO:0001657 43 22 0,000 0,05478135 0,07400557 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05478135 0,07396404 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05478135 0,07392256 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05478135 0,07388112 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05478135 0,07383973 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05478135 0,07379839 ! sarcomere organization GO:0045214 30 22 0,000 0,05478135 0,07375709 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05478135 0,07371584 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05478135 0,07367463 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05478135 0,07363347 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05478135 0,07359236 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,05478135 0,07355129 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05719975 0,07675549 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05719975 0,07671271 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05719975 0,07666997 ! gluconeogenesis GO:0006094 33 23 0,000 0,05719975 0,07662728 ! viral genome replication GO:0019079 41 23 0,000 0,05719975 0,07658464 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05719975 0,07654204 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05719975 0,0764995 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05719975 0,076457 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05719975 0,07641455 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05719975 0,07637214 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05719975 0,07632978 ! visual behavior GO:0007632 42 23 0,000 0,05719975 0,07628747 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05719975 0,07624521 ! response to ethanol GO:0045471 46 23 0,000 0,05719975 0,07620299 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05719975 0,07616082 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05719975 0,07611869 ! peroxisome organization GO:0007031 37 23 0,000 0,05719975 0,07607661 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05719975 0,07603458 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05719975 0,0759926 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05719975 0,07595066 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05719975 0,07590877 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05719975 0,07586692 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05719975 0,07582512 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05719975 0,07578337 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05719975 0,07574166 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05719975 0,0757 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05719975 0,07565838 ! fatty acid transport GO:0015908 44 23 0,000 0,05719975 0,07561681 ! platelet activation GO:0030168 37 23 0,000 0,05719975 0,07557529 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05719975 0,07553381 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05719975 0,07549237 ! hormone transport GO:0009914 40 23 0,000 0,05719975 0,07545098 ! cell-cell recognition GO:0009988 25 23 0,000 0,05719975 0,07540964 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05719975 0,07536834 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05719975 0,07532709 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05719975 0,07528588 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05719975 0,07524472 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05961204 0,07837518 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05961204 0,07833238 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05961204 0,07828962 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05961204 0,07824691 ! vesicle docking GO:0048278 47 24 0,000 0,05961204 0,07820424 ! spinal cord development GO:0021510 47 24 0,000 0,05961204 0,07816162 ! vacuole organization GO:0007033 43 24 0,000 0,05961204 0,07811905 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05961204 0,07807653 ! digestive system process GO:0022600 39 24 0,000 0,05961204 0,07803405 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05961204 0,07799161 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05961204 0,07794923 ! regulation of behavior GO:0050795 43 24 0,000 0,05961204 0,07790689 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05961204 0,07786459 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05961204 0,07782234 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05961204 0,07778014 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05961204 0,07773798 ! membrane depolarization GO:0051899 39 24 0,000 0,05961204 0,07769587 ! pallium development GO:0021543 49 24 0,000 0,05961204 0,07765381 ! pentose metabolic process GO:0019321 35 24 0,000 0,05961204 0,07761179 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05961204 0,07756981 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05961204 0,07752788 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05961204 0,077486 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05961204 0,07744416 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05961204 0,07740236 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05961204 0,07736061 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05961204 0,07731891 ! regulation of amine transport GO:0051952 40 24 0,000 0,05961204 0,07727725 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06201825 0,08035321 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06201825 0,08030996 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06201825 0,08026676 ! phototransduction GO:0007602 33 25 0,000 0,06201825 0,0802236 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06201825 0,0801805 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06201825 0,08013743 ! sperm motility GO:0030317 31 25 0,000 0,06201825 0,08009442 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06201825 0,08005145 ! chromosome condensation GO:0030261 45 25 0,000 0,06201825 0,08000853 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06201825 0,07996565 ! neural crest cell development GO:0014032 54 25 0,000 0,06201825 0,07992282 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06201825 0,07988003 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06201825 0,07983729 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06201825 0,0797946 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06201825 0,07975195 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06201825 0,07970935 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,06201825 0,07966679 ! immunoglobulin production GO:0002377 55 25 0,000 0,06201825 0,07962428 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06201825 0,07958182 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06201825 0,07953939 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06201825 0,07949702 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06201825 0,07945469 ! telomere organization GO:0032200 43 25 0,000 0,06201825 0,0794124 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06201825 0,07937016 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06201825 0,07932797 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06441837 0,0823542 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06441837 0,08231047 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06441837 0,08226678 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06441837 0,08222313 ! initiation of viral infection GO:0019059 57 26 0,000 0,06441837 0,08217954 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06441837 0,08213599 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06441837 0,08209248 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06441837 0,08204902 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06441837 0,08200561 ! molting cycle process GO:0022404 50 26 0,000 0,06441837 0,08196225 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,06441837 0,08191893 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06441837 0,08187565 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06441837 0,08183242 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06441837 0,08178924 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,06441837 0,0817461 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06441837 0,08170301 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,06441837 0,08165996 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06441837 0,08161696 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06441837 0,081574 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06441837 0,08153109 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06441837 0,08148823 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06441837 0,08144541 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06441837 0,08140263 ! blastocyst development GO:0001824 49 26 0,000 0,06441837 0,0813599 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06441837 0,08131721 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06441837 0,08127457 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06441837 0,08123197 ! neuron fate commitment GO:0048663 48 27 0,000 0,06681244 0,08420677 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06681244 0,08416268 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,06681244 0,08411864 ! iron ion transport GO:0006826 59 27 0,000 0,06681244 0,08407465 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06681244 0,0840307 ! protein amino acid acylation GO:0043543 55 27 0,000 0,06681244 0,08398679 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06681244 0,08394294 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06681244 0,08389913 ! fat cell differentiation GO:0045444 50 27 0,000 0,06681244 0,08385536 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06681244 0,08381164 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06681244 0,08376797 ! autophagy GO:0006914 41 27 0,000 0,06681244 0,08372434 ! male gonad development GO:0008584 44 27 0,000 0,06681244 0,08368075 ! response to toxin GO:0009636 47 27 0,000 0,06681244 0,08363721 ! primary neural tube formation GO:0014020 51 27 0,000 0,06681244 0,08359372 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06681244 0,08355027 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06681244 0,08350687 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06681244 0,08346351 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06681244 0,0834202 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06681244 0,08337693 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06681244 0,08333371 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06681244 0,08329053 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06920046 0,08622284 ! circadian rhythm GO:0007623 50 28 0,000 0,06920046 0,08617821 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06920046 0,08613362 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,06920046 0,08608909 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,06920046 0,0860446 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06920046 0,08600015 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06920046 0,08595575 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06920046 0,0859114 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06920046 0,08586709 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06920046 0,08582283 ! synaptogenesis GO:0007416 42 28 0,000 0,06920046 0,08577862 ! lipid oxidation GO:0034440 43 28 0,000 0,06920046 0,08573445 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06920046 0,08569032 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06920046 0,08564624 ! translational initiation GO:0006413 65 29 0,000 0,07158244 0,08854877 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07158244 0,08850326 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07158244 0,08845781 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,07158244 0,0884124 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07158244 0,08836704 ! catechol metabolic process GO:0009712 54 29 0,000 0,07158244 0,08832172 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07158244 0,08827645 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07158244 0,08823123 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07158244 0,08818605 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07158244 0,08814092 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07158244 0,08809583 ! cell fate determination GO:0001709 60 29 0,000 0,07158244 0,08805079 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07158244 0,0880058 ! detection of light stimulus GO:0009583 38 29 0,000 0,07158244 0,08796085 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,07158244 0,08791595 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07158244 0,0878711 ! tissue homeostasis GO:0001894 48 29 0,000 0,07158244 0,08782629 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,07158244 0,08778153 ! phenol metabolic process GO:0018958 55 30 0,000 0,07395841 0,09064897 ! zinc ion transport GO:0006829 45 30 0,000 0,07395841 0,09060282 ! membrane docking GO:0022406 61 30 0,000 0,07395841 0,09055671 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07395841 0,09051065 ! cell junction assembly GO:0034329 78 30 0,000 0,07395841 0,09046463 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07395841 0,09041867 ! acute-phase response GO:0006953 49 30 0,000 0,07395841 0,09037274 ! myofibril assembly GO:0030239 47 30 0,000 0,07395841 0,09032687 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07395841 0,09028104 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07395841 0,09023526 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07395841 0,09018953 ! phospholipid transport GO:0015914 51 30 0,000 0,07395841 0,09014384 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07395841 0,09009819 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07395841 0,0900526 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07395841 0,09000705 ! eye morphogenesis GO:0048592 60 30 0,000 0,07395841 0,08996154 ! response to heat GO:0009408 50 30 0,000 0,07395841 0,08991609 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,07632838 0,09275054 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,07632838 0,09270372 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,07632838 0,09265695 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,07632838 0,09261022 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,07632838 0,09256355 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,07632838 0,09251691 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,07632838 0,09247033 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,07632838 0,09242379 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,07632838 0,0923773 ! ovulation cycle process GO:0022602 49 31 0,000 0,07632838 0,09233086 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,07632838 0,09228446 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,07632838 0,09223811 ! peptide transport GO:0015833 55 31 0,000 0,07632838 0,0921918 ! iron ion homeostasis GO:0055072 54 31 0,000 0,07632838 0,09214555 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,07632838 0,09209934 ! mesoderm formation GO:0001707 69 31 0,000 0,07632838 0,09205317 ! natural killer cell activation GO:0030101 45 31 0,000 0,07632838 0,09200705 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,07632838 0,09196098 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,07632838 0,09191495 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,07632838 0,09186897 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,07632838 0,09182304 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07869236 0,0946196 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07869236 0,09457233 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07869236 0,09452512 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07869236 0,09447795 ! cholesterol transport GO:0030301 56 32 0,000 0,07869236 0,09443083 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07869236 0,09438375 ! spliceosome assembly GO:0000245 67 32 0,000 0,07869236 0,09433673 ! spindle organization GO:0007051 46 32 0,000 0,07869236 0,09428975 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07869236 0,09424281 ! metanephros development GO:0001656 74 32 0,000 0,07869236 0,09419593 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07869236 0,09414909 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07869236 0,09410229 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07869236 0,09405554 ! muscle cell development GO:0055001 49 32 0,000 0,07869236 0,09400884 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07869236 0,09396219 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07869236 0,09391558 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07869236 0,09386902 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07869236 0,0938225 ! ovulation cycle GO:0042698 51 32 0,000 0,07869236 0,09377603 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07869236 0,09372961 ! hindbrain development GO:0030902 61 32 0,000 0,07869236 0,09368323 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07869236 0,0936369 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07869236 0,09359061 ! gene silencing GO:0016458 65 32 0,000 0,07869236 0,09354437 ! post-embryonic development GO:0009791 69 33 0,000 0,08105037 0,09629984 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08105037 0,09625231 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,08105037 0,09620483 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08105037 0,09615739 ! formation of primary germ layer GO:0001704 72 33 0,000 0,08105037 0,09611 ! cell fate specification GO:0001708 52 33 0,000 0,08105037 0,09606265 ! sterol transport GO:0015918 57 33 0,000 0,08105037 0,09601535 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,08105037 0,0959681 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,08105037 0,0959209 ! adult locomotory behavior GO:0008344 59 33 0,000 0,08105037 0,09587374 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08105037 0,09582662 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08340242 0,09855905 ! glial cell differentiation GO:0010001 63 34 0,000 0,08340242 0,09851066 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08340242 0,09846232 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08340242 0,09841403 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08340242 0,09836579 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,08340242 0,0983176 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,08340242 0,09826945 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,08340242 0,09822135 ! mismatch repair GO:0006298 46 34 0,000 0,08340242 0,0981733 ! spermatid development GO:0007286 63 34 0,000 0,08340242 0,09812529 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08340242 0,09807733 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08340242 0,09802942 ! placenta development GO:0001890 53 34 0,000 0,08340242 0,09798155 ! regulation of muscle development GO:0048634 70 35 0,000 0,08574853 0,10068861 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,08574853 0,10063949 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,08574853 0,10059042 ! odontogenesis GO:0042476 66 35 0,000 0,08574853 0,1005414 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,08574853 0,10049243 ! female gonad development GO:0008585 58 35 0,000 0,08574853 0,1004435 ! telencephalon development GO:0021537 68 35 0,000 0,08574853 0,10039463 ! cytokine production GO:0001816 59 35 0,000 0,08574853 0,1003458 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,08574853 0,10029701 ! neural tube formation GO:0001841 67 35 0,000 0,08574853 0,10024828 ! vesicle localization GO:0051648 64 35 0,000 0,08574853 0,10019959 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,08808871 0,10288419 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,08808871 0,10283427 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,08808871 0,1027844 ! cell junction organization GO:0034330 86 36 0,000 0,08808871 0,10273458 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,08808871 0,1026848 ! positive regulation of cell development GO:0010720 80 36 0,000 0,08808871 0,10263508 ! regulation of proteolysis GO:0030162 72 36 0,000 0,08808871 0,1025854 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,08808871 0,10253577 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,08808871 0,10248619 ! aerobic respiration GO:0009060 55 36 0,000 0,08808871 0,10243665 ! embryonic organ development GO:0048568 57 36 0,000 0,08808871 0,10238717 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,08808871 0,10233773 ! RNA export from nucleus GO:0006405 56 37 0,000 0,09042298 0,10499888 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,09042298 0,10494823 ! meiosis I GO:0007127 65 37 0,000 0,09042298 0,10489763 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,09042298 0,10484708 ! sister chromatid segregation GO:0000819 58 37 0,000 0,09042298 0,10479657 ! actomyosin structure organization GO:0031032 62 37 0,000 0,09042298 0,10474612 ! organic anion transport GO:0015711 68 37 0,000 0,09042298 0,10469571 ! tissue remodeling GO:0048771 76 37 0,000 0,09042298 0,10464535 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,09042298 0,10459504 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,09042298 0,10454478 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,09042298 0,10449457 ! pigment metabolic process GO:0042440 80 37 0,000 0,09042298 0,1044444 ! spermatid differentiation GO:0048515 66 37 0,000 0,09042298 0,10439428 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,09275135 0,10703106 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,09275135 0,10697975 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,09275135 0,10692849 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,09275135 0,10687728 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,09275135 0,10682611 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,09275135 0,106775 ! lipid homeostasis GO:0055088 67 38 0,000 0,09275135 0,10672394 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,09275135 0,10667292 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,09275135 0,10662195 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,09275135 0,10657104 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,09275135 0,10652017 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,09275135 0,10646935 ! glucan metabolic process GO:0044042 62 38 0,000 0,09275135 0,10641857 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,09507384 0,1090313 ! ear morphogenesis GO:0042471 60 39 0,000 0,09507384 0,10897935 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,09507384 0,10892746 ! segmentation GO:0035282 67 39 0,000 0,09507384 0,10887561 ! ion transmembrane transport GO:0034220 66 39 0,000 0,09507384 0,10882382 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,09507384 0,10877207 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,09507384 0,10872037 ! RNA modification GO:0009451 57 39 0,000 0,09507384 0,10866872 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,09507384 0,10861712 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,09739046 0,11121094 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,09739046 0,11115818 ! feeding behavior GO:0007631 59 40 0,000 0,09739046 0,11110548 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,09739046 0,11105282 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,09739046 0,11100021 ! cytokinesis GO:0000910 72 40 0,000 0,09739046 0,11094766 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,09970123 0,11352634 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,09970123 0,11347264 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,09970123 0,11341899 ! female gamete generation GO:0007292 61 41 0,000 0,09970123 0,11336538 ! polyol metabolic process GO:0019751 66 41 0,000 0,09970123 0,11331183 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,09970123 0,11325834 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,10200616 0,115822 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,10200616 0,11576736 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,10200616 0,11571278 ! regulation of tube size GO:0035150 71 42 0,000 0,10200616 0,11565825 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,10200616 0,11560377 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,10200616 0,11554935 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,10200616 0,11549497 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,10200616 0,11544064 ! neuron migration GO:0001764 79 42 0,000 0,10200616 0,11538637 ! regulation of protein secretion GO:0050708 71 42 0,000 0,10200616 0,11533215 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,10430526 0,11787621 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,10430526 0,11782087 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,10430526 0,11776558 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,10430526 0,11771034 ! glucose transport GO:0015758 65 43 0,000 0,10430526 0,11765516 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,10430526 0,11760002 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,10430526 0,11754494 ! neural tube development GO:0021915 77 43 0,000 0,10430526 0,11748991 ! striated muscle contraction GO:0006941 77 43 0,000 0,10430526 0,11743493 ! phagocytosis GO:0006909 90 43 0,000 0,10430526 0,11738001 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,10430526 0,11732513 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,10659855 0,11984865 ! hexose transport GO:0008645 67 44 0,000 0,10659855 0,11979267 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,10659855 0,11973675 ! male sex differentiation GO:0046661 76 44 0,000 0,10659855 0,11968087 ! biopolymer methylation GO:0043414 84 44 0,000 0,10659855 0,11962505 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,10659855 0,11956928 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,10659855 0,11951357 ! developmental growth GO:0048589 82 44 0,000 0,10659855 0,1194579 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,10888605 0,12196454 ! glycolysis GO:0006096 65 45 0,000 0,10888605 0,12190779 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,10888605 0,12185109 ! leukocyte migration GO:0050900 68 45 0,000 0,10888605 0,12179444 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,10888605 0,12173784 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,10888605 0,1216813 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,10888605 0,12162481 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,10888605 0,12156837 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,10888605 0,12151198 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,10888605 0,12145565 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,10888605 0,12139937 ! cell growth GO:0016049 84 45 0,000 0,10888605 0,12134314 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,11116777 0,12382854 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,11116777 0,12377124 ! pigmentation GO:0043473 100 46 0,000 0,11116777 0,12371399 ! positive regulation of defense response GO:0031349 76 47 0,000 0,11344371 0,12618843 ! response to calcium ion GO:0051592 81 47 0,000 0,11344371 0,12613012 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,11344371 0,12607186 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,11344371 0,12601366 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,11344371 0,1259555 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,11344371 0,12589741 ! JNK cascade GO:0007254 91 47 0,000 0,11344371 0,12583936 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,11344371 0,12578137 ! methylation GO:0032259 90 47 0,000 0,11344371 0,12572344 ! Notch signaling pathway GO:0007219 96 48 0,000 0,11571391 0,12818033 ! cellular component disassembly GO:0022411 86 48 0,000 0,11571391 0,12812134 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,11571391 0,12806241 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,11571391 0,12800353 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,11571391 0,1279447 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,11571391 0,12788593 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,11571391 0,12782721 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,11797837 0,13026891 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,11797837 0,13020916 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,11797837 0,13014946 ! regulation of ion transport GO:0043269 77 49 0,000 0,11797837 0,13008981 ! peptide metabolic process GO:0006518 76 49 0,000 0,11797837 0,13003022 ! response to temperature stimulus GO:0009266 76 49 0,000 0,11797837 0,12997068 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,11797837 0,1299112 ! endocrine system development GO:0035270 104 49 0,000 0,11797837 0,12985177 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,11797837 0,12979239 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,11797837 0,12973307 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,11797837 0,12967381 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,11797837 0,12961459 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,12023711 0,13203582 ! neuromuscular process GO:0050905 99 50 0,000 0,12023711 0,13197558 ! inner ear development GO:0048839 79 50 0,000 0,12023711 0,1319154 ! histone modification GO:0016570 91 50 0,000 0,12023711 0,13185528 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,12023711 0,13179521 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,12023711 0,13173519 ! positive regulation of binding GO:0051099 78 51 0,000 0,12249013 0,13414259 ! viral infectious cycle GO:0019058 99 51 0,000 0,12249013 0,13408156 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,12249013 0,13402058 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,12249013 0,13395966 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,12249013 0,1338988 ! excretion GO:0007588 83 51 0,000 0,12249013 0,13383799 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,12249013 0,13377724 ! chromatin remodeling GO:0006338 109 51 0,000 0,12249013 0,13371654 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,12249013 0,1336559 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,12249013 0,13359531 ! vesicle organization GO:0016050 107 51 0,000 0,12249013 0,13353478 ! regulation of cell shape GO:0008360 125 51 0,000 0,12249013 0,1334743 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,12249013 0,13341388 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,12473746 0,13580015 ! membrane fusion GO:0006944 110 52 0,000 0,12473746 0,13573873 ! covalent chromatin modification GO:0016569 101 52 0,000 0,12473746 0,13567737 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,12473746 0,13561606 ! amino acid activation GO:0043038 92 52 0,000 0,12473746 0,13555481 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,12473746 0,13549361 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,12697912 0,13786631 ! RNA catabolic process GO:0006401 93 53 0,000 0,12697912 0,13780413 ! regulation of translational initiation GO:0006446 82 53 0,000 0,12697912 0,137742 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,12697912 0,13767992 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,12697912 0,13761791 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,12697912 0,13755594 ! cell maturation GO:0048469 100 53 0,000 0,12697912 0,13749404 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,12697912 0,13743219 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,1292151 0,13978936 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,1292151 0,13972653 ! cell recognition GO:0008037 85 54 0,000 0,1292151 0,13966376 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,1292151 0,13960105 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,1292151 0,13953839 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,1292151 0,13947579 ! chloride transport GO:0006821 90 55 0,000 0,13144543 0,1418196 ! glucose catabolic process GO:0006007 82 55 0,000 0,13144543 0,14175603 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,13144543 0,14169252 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,13144543 0,14162907 ! gastrulation GO:0007369 112 55 0,000 0,13144543 0,14156567 ! RNA elongation GO:0006354 79 55 0,000 0,13144543 0,14150233 ! nuclear export GO:0051168 97 55 0,000 0,13144543 0,14143904 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,13144543 0,14137582 ! regulation of actin filament length GO:0030832 105 56 0,000 0,13367012 0,14370434 ! sensory perception of smell GO:0007608 80 56 0,000 0,13367012 0,14364016 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,13367012 0,14357603 ! proton transport GO:0015992 94 56 0,000 0,13367012 0,14351196 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,13367012 0,14344795 ! hydrogen transport GO:0006818 97 58 0,000 0,13810265 0,14813864 ! regulation of endocytosis GO:0030100 91 58 0,000 0,13810265 0,14807262 ! adult behavior GO:0030534 99 58 0,000 0,13810265 0,14800667 ! regulation of cellular component size GO:0032535 109 59 0,000 0,14031051 0,15030591 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,14031051 0,15023902 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,14031051 0,15017219 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,14031051 0,15010542 ! DNA catabolic process GO:0006308 86 59 0,000 0,14031051 0,1500387 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,14031051 0,14997205 ! establishment of organelle localization GO:0051656 109 59 0,000 0,14031051 0,14990545 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,14251279 0,15219075 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,14251279 0,15212323 ! regulation of heart contraction GO:0008016 110 60 0,000 0,14251279 0,15205577 ! camera-type eye development GO:0043010 116 60 0,000 0,14251279 0,15198837 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,14251279 0,15192103 ! kidney development GO:0001822 122 60 0,000 0,14251279 0,15185375 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,1447095 0,15412618 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,1447095 0,15405799 ! mesoderm development GO:0007498 119 61 0,000 0,1447095 0,15398985 ! tRNA processing GO:0008033 89 61 0,000 0,1447095 0,15392177 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,1447095 0,15385376 ! ear development GO:0043583 103 62 0,000 0,14690065 0,15611439 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,14690065 0,15604546 ! gonad development GO:0008406 98 62 0,000 0,14690065 0,1559766 ! regulation of mitosis GO:0007088 105 63 0,000 0,14908627 0,15822742 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,14908627 0,15815765 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,14908627 0,15808795 ! detection of external stimulus GO:0009581 91 63 0,000 0,14908627 0,15801831 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,14908627 0,15794873 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,15126636 0,16018787 ! cell redox homeostasis GO:0045454 102 64 0,000 0,15126636 0,1601174 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,15126636 0,16004699 ! single fertilization GO:0007338 75 64 0,000 0,15126636 0,15997664 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,15344093 0,16220513 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,15344093 0,16213389 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,15344093 0,16206272 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,15344093 0,16199161 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,15344093 0,16192056 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,15561 0,16413751 ! extracellular matrix organization GO:0030198 133 66 0,000 0,15561 0,16406559 ! secondary metabolic process GO:0019748 116 66 0,000 0,15561 0,16399372 ! developmental maturation GO:0021700 116 66 0,000 0,15561 0,16392192 ! cell projection assembly GO:0030031 120 66 0,000 0,15561 0,16385018 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,15777359 0,16605567 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,15777359 0,16598306 ! lung development GO:0030324 144 67 0,000 0,15777359 0,16591052 ! chromosome segregation GO:0007059 113 67 0,000 0,15777359 0,16583804 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,15777359 0,16576562 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,15777359 0,16569326 ! hexose catabolic process GO:0019320 104 67 0,000 0,15777359 0,16562097 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,15777359 0,16554874 ! adaptive immune response GO:0002250 119 67 0,000 0,15777359 0,16547658 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,15777359 0,16540447 ! amino acid transport GO:0006865 125 68 0,000 0,15993171 0,16759395 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,15993171 0,16752098 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,15993171 0,16744808 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,15993171 0,16737525 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,15993171 0,16730248 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,16208437 0,16948066 ! urogenital system development GO:0001655 137 69 0,000 0,16208437 0,16940704 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,16208437 0,16933348 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,16208437 0,16925998 ! antigen processing and presentation GO:0019882 104 69 0,000 0,16208437 0,16918655 ! appendage morphogenesis GO:0035107 135 70 0,000 0,16423159 0,17135351 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,16423159 0,17127924 ! amine catabolic process GO:0009310 117 71 0,000 0,16637337 0,17343775 ! reproductive structure development GO:0048608 113 71 0,000 0,16637337 0,17336264 ! appendage development GO:0048736 136 71 0,000 0,16637337 0,17328759 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,16637337 0,1732126 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,16637337 0,17313768 ! regulation of immune effector process GO:0002697 137 71 0,000 0,16637337 0,17306283 ! acute inflammatory response GO:0002526 113 72 0,000 0,16850974 0,17520934 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,16850974 0,17513366 ! carbohydrate transport GO:0008643 110 72 0,000 0,16850974 0,17505804 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,16850974 0,17498249 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,16850974 0,174907 ! respiratory system development GO:0060541 153 72 0,000 0,16850974 0,17483158 ! regulation of blood pressure GO:0008217 125 73 0,000 0,1706407 0,17696617 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,1706407 0,17688993 ! fertilization GO:0009566 90 73 0,000 0,1706407 0,17681375 ! transition metal ion transport GO:0000041 126 74 0,000 0,17276627 0,17893915 ! neurotransmitter transport GO:0006836 123 74 0,000 0,17276627 0,17886215 ! exocytosis GO:0006887 133 74 0,000 0,17276627 0,17878522 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,17276627 0,17870836 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,17276627 0,17863156 ! eye development GO:0001654 143 74 0,000 0,17276627 0,17855483 ! organelle localization GO:0051640 136 74 0,000 0,17276627 0,17847816 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,17488646 0,18059091 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,17488646 0,18051344 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,17488646 0,18043603 ! rhythmic process GO:0048511 128 75 0,000 0,17488646 0,18035869 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,17700129 0,18246149 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,17700129 0,18238335 ! defense response to bacterium GO:0042742 89 76 0,000 0,17700129 0,18230527 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,17700129 0,18222726 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,17700129 0,18214932 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,17911077 0,18424135 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,17911077 0,18416262 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,17911077 0,18408395 ! blood coagulation GO:0007596 146 78 0,000 0,18121492 0,18616699 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,18121492 0,18608753 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,18121492 0,18600814 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,18121492 0,18592882 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,18331374 0,18800207 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,18331374 0,18792196 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,18331374 0,18784193 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,18331374 0,18776196 ! response to metal ion GO:0010038 140 80 0,000 0,18540725 0,18982546 ! muscle cell differentiation GO:0042692 159 80 0,000 0,18540725 0,18974472 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,18540725 0,18966405 ! inorganic anion transport GO:0015698 138 80 0,000 0,18540725 0,18958344 ! response to hypoxia GO:0001666 171 81 0,000 0,18749546 0,19163725 ! digestion GO:0007586 112 81 0,000 0,18749546 0,19155587 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,18749546 0,19147457 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,18749546 0,19139333 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,18749546 0,19131216 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,18957839 0,19335549 ! response to nutrient GO:0007584 125 82 0,000 0,18957839 0,19327356 ! response to oxygen levels GO:0070482 176 83 0,000 0,19165605 0,19530896 ! hemostasis GO:0007599 158 84 0,000 0,19372845 0,19733728 ! regulation of ligase activity GO:0051340 142 84 0,000 0,19372845 0,19725376 ! response to unfolded protein GO:0006986 131 85 0,000 0,1957956 0,19927421 ! nucleosome assembly GO:0006334 122 85 0,000 0,1957956 0,19918995 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,1957956 0,19910576 ! amine biosynthetic process GO:0009309 138 86 0,000 0,19785753 0,20111754 ! response to inorganic substance GO:0010035 153 86 0,000 0,19785753 0,20103261 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,19785753 0,20094775 ! chromatin assembly GO:0031497 124 86 0,000 0,19785753 0,20086296 ! tube morphogenesis GO:0035239 176 86 0,000 0,19785753 0,20077824 ! alcohol catabolic process GO:0046164 130 86 0,000 0,19785753 0,2006936 ! amine transport GO:0015837 155 86 0,000 0,19785753 0,20060902 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,19991424 0,20260895 ! cellular respiration GO:0045333 135 88 0,000 0,20196574 0,20460192 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,20196574 0,20451581 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,20196574 0,20442977 ! cellular defense response GO:0006968 114 89 0,000 0,20401205 0,20641421 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,20401205 0,20632744 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,20605318 0,20830418 ! sex differentiation GO:0007548 145 90 0,000 0,20605318 0,20821669 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,20605318 0,20812928 ! sterol metabolic process GO:0016125 152 91 0,000 0,20808914 0,21009756 ! response to protein stimulus GO:0051789 149 91 0,000 0,20808914 0,21000943 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,20808914 0,20992137 ! regulation of defense response GO:0031347 149 92 0,000 0,21011995 0,21188123 ! nucleosome organization GO:0034728 138 92 0,000 0,21011995 0,21179246 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,21011995 0,21170377 ! vitamin metabolic process GO:0006766 139 92 0,000 0,21011995 0,21161516 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,21214562 0,21356585 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,21214562 0,21347653 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,21214562 0,21338728 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,21416617 0,21532963 ! female pregnancy GO:0007565 164 94 0,000 0,21416617 0,21523968 ! transcription initiation GO:0006352 153 94 0,000 0,21416617 0,21514981 ! forebrain development GO:0030900 188 95 0,000 0,2161816 0,21708386 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,21819192 0,21901117 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,21819192 0,21891984 ! positive regulation of immune response GO:0050778 156 96 0,000 0,21819192 0,21882858 ! detection of stimulus GO:0051606 151 96 0,000 0,21819192 0,2187374 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,22019716 0,22065571 ! protein ubiquitination GO:0016567 217 97 0,000 0,22019716 0,22056385 ! response to virus GO:0009615 160 98 0,000 0,22219732 0,22247472 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,22219732 0,22238218 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,22219732 0,22228971 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,22419242 0,22419242