pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6542-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! release of cytochrome c from mitochondria GO:0001836 9 8 3,000 1,557E-07 2,87E-04 ! apoptotic mitochondrial changes GO:0008637 11 10 3,000 4,622E-07 4,259E-04 ! muscle cell migration GO:0014812 5 5 2,000 3,362E-06 2,065E-03 ! ectoderm development GO:0007398 99 99 6,000 5,405E-06 2,491E-03 ! ER overload response GO:0006983 6 6 2,000 6,69E-06 2,466E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 2,000 6,69E-06 2,055E-03 GO:0070667|negative regulation of mast cell proliferation, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 2,000 1,165E-05 3,067E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! negative regulation of T cell activation GO:0050868 7 7 2,000 1,165E-05 2,684E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 2,574E-05 5,271E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 3,000 3,026E-05 5,577E-03 ! regulation of protein transport GO:0051223 53 53 4,000 3,301E-05 5,531E-03 GO:0070201|regulation of establishment of protein localization, ! keratinocyte differentiation GO:0030216 28 28 3,000 4,101E-05 6,298E-03 ! regulation of protein localization GO:0032880 58 57 4,000 4,715E-05 6,684E-03 ! response to UV GO:0009411 29 29 3,000 4,732E-05 6,23E-03 ! microtubule-based transport GO:0010970 11 11 2,000 5,382E-05 6,613E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 5,382E-05 6,2E-03 GO:0032388|positive regulation of intracellular transport, ! negative regulation of lymphocyte activation GO:0051250 11 11 2,000 5,382E-05 5,835E-03 ! regulation of DNA replication GO:0006275 32 31 3,000 6,204E-05 6,352E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 6,204E-05 6,018E-03 ! epidermal cell differentiation GO:0009913 31 31 3,000 6,204E-05 5,717E-03 ! negative regulation of DNA replication GO:0008156 13 13 2,000 9,236E-05 8,106E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 9,236E-05 7,738E-03 ! negative regulation of leukocyte activation GO:0002695 13 13 2,000 9,236E-05 7,401E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 1,011E-04 7,764E-03 ! regulation of cell size GO:0008361 68 68 4,000 1,107E-04 8,159E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,17E-04 8,291E-03 ! negative regulation of protein kinase activity GO:0006469 37 37 3,000 1,262E-04 8,614E-03 ! DNA damage response, signal transduction GO:0042770 37 37 3,000 1,262E-04 8,306E-03 ! negative regulation of kinase activity GO:0033673 38 38 3,000 1,403E-04 8,917E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 1,455E-04 8,937E-03 ! negative regulation of cell activation GO:0050866 15 15 2,000 1,455E-04 8,649E-03 ! protein homooligomerization GO:0051260 15 15 2,000 1,455E-04 8,379E-03 ! protein oligomerization GO:0051259 39 39 3,000 1,555E-04 8,686E-03 ! negative regulation of transferase activity GO:0051348 40 40 3,000 1,719E-04 9,318E-03 ! regulation of caspase activity GO:0043281 41 41 3,000 1,895E-04 9,978E-03 ! regulation of endopeptidase activity GO:0052548 42 42 3,000 2,084E-04 0,01066648 ! positive regulation of cell adhesion GO:0045785 17 17 2,000 2,152E-04 0,01072154 ! mitochondrion organization GO:0007005 44 43 3,000 2,285E-04 0,0110834 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 2,57E-04 0,01214501 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 2,73E-04 0,01257991 ! regulation of peptidase activity GO:0052547 46 46 3,000 2,975E-04 0,01337188 ! DNA damage checkpoint GO:0000077 19 19 2,000 3,037E-04 0,01332509 ! negative regulation of DNA metabolic process GO:0051053 19 19 2,000 3,037E-04 0,0130152 ! regulation of cellular localization GO:0060341 86 85 4,000 3,181E-04 0,01332365 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 2,000 3,555E-04 0,01455833 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 4,111E-04 0,01647233 ! DNA integrity checkpoint GO:0031570 21 21 2,000 4,126E-04 0,01618069 ! negative regulation of hydrolase activity GO:0051346 21 21 2,000 4,126E-04 0,0158436 ! negative regulation of protein transport GO:0051224 21 21 2,000 4,126E-04 0,01552026 ! negative regulation of cell cycle GO:0045786 92 91 4,000 4,368E-04 0,01609965 ! response to light stimulus GO:0009416 53 52 3,000 4,783E-04 0,01728384 ! prostate gland development GO:0030850 5 5 1,000 4,902E-04 0,01737398 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 4,902E-04 0,01704617 ! T cell lineage commitment GO:0002360 5 5 1,000 4,902E-04 0,0167305 ! regulation of DNA replication initiation GO:0030174 5 5 1,000 4,902E-04 0,01642631 ! peptidyl-lysine modification GO:0018205 5 5 1,000 4,902E-04 0,01613298 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 4,902E-04 0,01584995 ! epidermis development GO:0008544 94 94 4,000 5,074E-04 0,0161221 ! response to hypoxia GO:0001666 53 53 3,000 5,146E-04 0,01607571 ! response to oxygen levels GO:0070482 55 54 3,000 5,529E-04 0,01698349 ! regulation of cell growth GO:0001558 97 96 4,000 5,59E-04 0,01688893 ! T cell differentiation GO:0030217 24 24 2,000 6,186E-04 0,01838813 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 6,186E-04 0,01809626 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 4,000 6,74E-04 0,01940919 ! regulation of T cell proliferation GO:0042129 25 25 2,000 6,994E-04 0,01983167 ! negative regulation of immune system process GO:0002683 25 25 2,000 6,994E-04 0,01953119 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 7,32E-04 0,02013441 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of B cell proliferation GO:0030888 6 6 1,000 7,32E-04 0,01983832 ! regulation of activated T cell proliferation GO:0046006 6 6 1,000 7,32E-04 0,01955081 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 7,32E-04 0,01927151 ! positive regulation of cell growth GO:0030307 6 6 1,000 7,32E-04 0,01900008 ! asymmetric protein localization GO:0008105 6 6 1,000 7,32E-04 0,01873619 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 7,32E-04 0,01847953 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 7,32E-04 0,01822981 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 7,32E-04 0,01798674 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 7,32E-04 0,01775007 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 7,32E-04 0,01751955 ! regulation of Rho GTPase activity GO:0032319 6 6 1,000 7,32E-04 0,01729494 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 7,32E-04 0,01707602 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 1,000 7,32E-04 0,01686257 ! localization within membrane GO:0051668 6 6 1,000 7,32E-04 0,01665439 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 8,806E-04 0,01979296 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 9,814E-04 0,02179175 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 9,814E-04 0,02153233 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 1,02E-03 0,02211788 ! keratinocyte proliferation GO:0043616 7 7 1,000 1,02E-03 0,0218607 ! response to X-ray GO:0010165 7 7 1,000 1,02E-03 0,02160943 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,02E-03 0,02136386 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 1,000 1,02E-03 0,02112382 ! axon cargo transport GO:0008088 7 7 1,000 1,02E-03 0,02088911 ! negative regulation of cytokine secretion GO:0050710 7 7 1,000 1,02E-03 0,02065956 ! regulation of interleukin-1 secretion GO:0050704 7 7 1,000 1,02E-03 0,020435 ! response to gamma radiation GO:0010332 8 7 1,000 1,02E-03 0,02021527 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,089E-03 0,02135479 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 1,089E-03 0,02113 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! positive regulation of protein transport GO:0051222 29 29 2,000 1,089E-03 0,0209099 ! response to radiation GO:0009314 70 68 3,000 1,324E-03 0,02514685 ! regulation of stress fiber formation GO:0051492 9 8 1,000 1,354E-03 0,02546225 ! fructose metabolic process GO:0006000 8 8 1,000 1,354E-03 0,02520506 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,354E-03 0,02495301 ! regulation of cytokine production during immune response GO:0002718 8 8 1,000 1,354E-03 0,02470595 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 1,354E-03 0,02446373 ! T cell homeostasis GO:0043029 8 8 1,000 1,354E-03 0,02422622 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,354E-03 0,02399327 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,354E-03 0,02376477 ! negative regulation of cell growth GO:0030308 32 32 2,000 1,456E-03 0,02532317 ! wound healing GO:0042060 74 70 3,000 1,475E-03 0,02540003 ! negative regulation of cell size GO:0045792 33 33 2,000 1,594E-03 0,02720339 ! positive regulation of hydrolase activity GO:0051345 72 72 3,000 1,637E-03 0,02768679 ! positive regulation of cell size GO:0045793 9 9 1,000 1,733E-03 0,02903335 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,733E-03 0,02877179 ! phospholipid efflux GO:0033700 9 9 1,000 1,733E-03 0,0285149 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,733E-03 0,02826256 ! reverse cholesterol transport GO:0043691 9 9 1,000 1,733E-03 0,02801464 ! negative regulation of caspase activity GO:0043154 9 9 1,000 1,733E-03 0,02777103 ! regulation of dephosphorylation GO:0035303 9 9 1,000 1,733E-03 0,02753163 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,733E-03 0,02729632 ! regulation of cellular pH GO:0030641 9 9 1,000 1,733E-03 0,02706499 ! histone acetylation GO:0016573 9 9 1,000 1,733E-03 0,02683755 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 1,733E-03 0,02661391 ! negative regulation of protein secretion GO:0050709 9 9 1,000 1,733E-03 0,02639396 ! cholesterol efflux GO:0033344 9 9 1,000 1,733E-03 0,02617761 ! regulation of actin filament bundle formation GO:0032231 10 9 1,000 1,733E-03 0,02596479 ! coagulation GO:0050817 39 36 2,000 2,055E-03 0,03054519 GO:0007596|blood coagulation, ! regulation of protein ubiquitination GO:0031396 10 10 1,000 2,156E-03 0,03179167 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 2,156E-03 0,03153936 ! induction of apoptosis via death domain receptors GO:0008625 10 10 1,000 2,156E-03 0,03129102 ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 2,156E-03 0,03104656 ! neuromuscular junction development GO:0007528 10 10 1,000 2,156E-03 0,03080588 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 2,156E-03 0,03056892 ! lymphocyte homeostasis GO:0002260 10 10 1,000 2,156E-03 0,03033557 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 2,156E-03 0,03010575 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,156E-03 0,02987939 ! negative regulation of coagulation GO:0050819 11 10 1,000 2,156E-03 0,02965641 ! protein stabilization GO:0050821 10 10 1,000 2,156E-03 0,02943673 ! negative regulation of growth GO:0045926 37 37 2,000 2,225E-03 0,03015648 ! regulation of Rho protein signal transduction GO:0035023 37 37 2,000 2,225E-03 0,02993636 ! exocytosis GO:0006887 40 38 2,000 2,404E-03 0,0321062 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 2,404E-03 0,03187522 ! hemostasis GO:0007599 42 39 2,000 2,591E-03 0,03411422 ! lymphocyte differentiation GO:0030098 39 39 2,000 2,591E-03 0,03387227 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 2,623E-03 0,03404941 ! phosphatidylinositol metabolic process GO:0046488 11 11 1,000 2,623E-03 0,03381131 ! skin development GO:0043588 11 11 1,000 2,623E-03 0,03357651 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,623E-03 0,03334494 ! cellular response to starvation GO:0009267 11 11 1,000 2,623E-03 0,03311655 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 2,623E-03 0,03289127 ! apoptotic nuclear changes GO:0030262 11 11 1,000 2,623E-03 0,03266903 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 2,623E-03 0,03244978 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,623E-03 0,03223345 ! intermediate filament-based process GO:0045103 11 11 1,000 2,623E-03 0,03201998 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,623E-03 0,03180932 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 2,788E-03 0,03357872 ! cell cycle checkpoint GO:0000075 42 41 2,000 2,993E-03 0,03581538 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 3,134E-03 0,03726258 ! phosphatidylcholine metabolic process GO:0046470 12 12 1,000 3,134E-03 0,03702371 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 1,000 3,134E-03 0,0367879 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 3,134E-03 0,03655506 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 3,134E-03 0,03632515 ! actomyosin structure organization GO:0031032 12 12 1,000 3,134E-03 0,03609812 ! somitogenesis GO:0001756 13 12 1,000 3,134E-03 0,03587391 ! G1 phase GO:0051318 13 12 1,000 3,134E-03 0,03565247 ! neurotransmitter secretion GO:0007269 14 12 1,000 3,134E-03 0,03543374 ! negative regulation of translation GO:0017148 12 12 1,000 3,134E-03 0,03521768 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 3,134E-03 0,03500424 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 3,134E-03 0,03479337 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 2,000 3,207E-03 0,03539105 ! heart development GO:0007507 90 87 3,000 3,277E-03 0,03594668 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 3,663E-03 0,03994587 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 3,687E-03 0,03996986 ! negative regulation of protein modification process GO:0031400 13 13 1,000 3,687E-03 0,03973612 ! mitochondrial membrane organization GO:0007006 13 13 1,000 3,687E-03 0,03950509 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 3,687E-03 0,03927674 ! cell aging GO:0007569 13 13 1,000 3,687E-03 0,03905101 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 3,687E-03 0,03882786 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 3,687E-03 0,03860725 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 3,687E-03 0,03838913 GO:0001952|regulation of cell-matrix adhesion, ! protein tetramerization GO:0051262 13 13 1,000 3,687E-03 0,03817346 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 3,905E-03 0,04020734 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 4,157E-03 0,04256104 ! positive regulation of ligase activity GO:0051351 47 46 2,000 4,157E-03 0,0423259 ! protein amino acid acylation GO:0043543 14 14 1,000 4,282E-03 0,04335949 ! peptide cross-linking GO:0018149 14 14 1,000 4,282E-03 0,04312255 ! base-excision repair GO:0006284 14 14 1,000 4,282E-03 0,04288819 ! regulation of blood coagulation GO:0030193 15 14 1,000 4,282E-03 0,04265636 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 4,689E-03 0,04646452 ! glycerophospholipid metabolic process GO:0006650 49 48 2,000 4,689E-03 0,04621604 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 4,918E-03 0,04821407 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 4,918E-03 0,04795897 ! response to starvation GO:0042594 15 15 1,000 4,918E-03 0,04770655 ! response to ionizing radiation GO:0010212 16 15 1,000 4,918E-03 0,04745678 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 1,000 4,918E-03 0,04720961 ! phospholipid transport GO:0015914 15 15 1,000 4,918E-03 0,046965 ! leukocyte homeostasis GO:0001776 15 15 1,000 4,918E-03 0,04672291 ! regulation of cytokine secretion GO:0050707 15 15 1,000 4,918E-03 0,04648331 ! leukocyte differentiation GO:0002521 50 49 2,000 4,97E-03 0,04673639 ! gland development GO:0048732 51 49 2,000 4,97E-03 0,04649915 ! cell cycle arrest GO:0007050 49 49 2,000 4,97E-03 0,04626431 ! skeletal muscle tissue development GO:0007519 50 49 2,000 4,97E-03 0,04603182 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 4,97E-03 0,04580167 ! regulation of ligase activity GO:0051340 50 49 2,000 4,97E-03 0,0455738 ! negative regulation of transport GO:0051051 51 50 2,000 5,261E-03 0,04800331 ! T cell activation GO:0042110 51 50 2,000 5,261E-03 0,04776685 ! regulation of neurogenesis GO:0050767 51 50 2,000 5,261E-03 0,04753269 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 5,562E-03 0,05000776 GO:0051325|interphase, ! regulation of synaptic plasticity GO:0048167 16 16 1,000 5,595E-03 0,05005938 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 5,595E-03 0,04981755 ! segmentation GO:0035282 17 16 1,000 5,595E-03 0,04957804 ! cellular response to nutrient levels GO:0031669 16 16 1,000 5,595E-03 0,04934082 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 5,595E-03 0,04910587 ! ethanolamine and derivative metabolic process GO:0042439 17 16 1,000 5,595E-03 0,04887314 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 5,595E-03 0,04864261 ! regulation of coagulation GO:0050818 17 16 1,000 5,595E-03 0,04841424 ! cell fate commitment GO:0045165 52 52 2,000 5,874E-03 0,05058538 ! regulation of body fluid levels GO:0050878 55 52 2,000 5,874E-03 0,0503501 ! regulation of T cell activation GO:0050863 53 53 2,000 6,195E-03 0,05286055 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 6,313E-03 0,0536143 ! myelination GO:0042552 17 17 1,000 6,313E-03 0,05336837 ! negative regulation of cell development GO:0010721 18 17 1,000 6,313E-03 0,05312467 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 6,313E-03 0,0528832 ! regulation of cell adhesion GO:0030155 56 55 2,000 6,87E-03 0,05728743 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 7,07E-03 0,05869092 ! cholesterol homeostasis GO:0042632 18 18 1,000 7,07E-03 0,05842773 GO:0055092|sterol homeostasis, ! B cell differentiation GO:0030183 18 18 1,000 7,07E-03 0,0581669 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 7,07E-03 0,05790838 ! ensheathment of neurons GO:0007272 18 18 1,000 7,07E-03 0,05765215 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 7,07E-03 0,05739817 ! regulation of nervous system development GO:0051960 57 56 2,000 7,222E-03 0,05838098 ! regulation of pH GO:0006885 19 19 1,000 7,866E-03 0,06330311 ! peripheral nervous system development GO:0007422 19 19 1,000 7,866E-03 0,06302788 ! regulation of protein stability GO:0031647 19 19 1,000 7,866E-03 0,06275503 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 8,345E-03 0,0662917 ! regulation of cell development GO:0060284 60 59 2,000 8,345E-03 0,06600719 ! nucleus organization GO:0006997 20 20 1,000 8,7E-03 0,06852279 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 8,7E-03 0,0682312 ! regulation of B cell activation GO:0050864 20 20 1,000 8,7E-03 0,06794209 ! proteasomal protein catabolic process GO:0010498 62 61 2,000 9,147E-03 0,0711323 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 9,565E-03 0,0740668 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 9,565E-03 0,0737569 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 9,572E-03 0,07350877 ! mammary gland development GO:0030879 23 21 1,000 9,572E-03 0,07320376 ! cholesterol transport GO:0030301 21 21 1,000 9,572E-03 0,07290126 GO:0015918|sterol transport, ! regulation of protein import into nucleus GO:0042306 21 21 1,000 9,572E-03 0,07260126 ! regulation of action potential in neuron GO:0019228 21 21 1,000 9,572E-03 0,07230371 ! glycerolipid metabolic process GO:0046486 65 64 2,000 0,01043297 0,07848145 ! regulation of cytoskeleton organization GO:0051493 66 64 2,000 0,01043297 0,07816242 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,0104822 0,07821336 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 1,000 0,0104822 0,07789798 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,0104822 0,07758514 ! neuron migration GO:0001764 22 22 1,000 0,0104822 0,0772748 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 0,01088371 0,07991502 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 0,01134562 0,08297608 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0114287 0,08325333 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 0,0114287 0,08292556 ! positive regulation of growth GO:0045927 23 23 1,000 0,0114287 0,08260036 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,0114287 0,08227771 ! lipid homeostasis GO:0055088 23 23 1,000 0,0114287 0,08195756 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,0114287 0,08163989 ! Rho protein signal transduction GO:0007266 24 23 1,000 0,0114287 0,08132468 ! cell projection assembly GO:0030031 25 23 1,000 0,0114287 0,0810119 ! striated muscle tissue development GO:0014706 69 67 2,000 0,01181875 0,08345575 ! mitochondrial transport GO:0006839 24 24 1,000 0,01241144 0,0873064 ! regulation of action potential GO:0001508 24 24 1,000 0,01241144 0,08697444 ! maintenance of protein location GO:0045185 25 24 1,000 0,01241144 0,08664499 ! glucan metabolic process GO:0044042 25 24 1,000 0,01241144 0,08631803 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! sensory perception of sound GO:0007605 71 69 2,000 0,01279885 0,08867772 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01279885 0,08834559 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 0,01279885 0,08801595 ! positive regulation of transport GO:0051050 71 70 2,000 0,0133059 0,09116272 ! muscle tissue development GO:0060537 72 70 2,000 0,0133059 0,09082508 ! negative regulation of secretion GO:0051048 26 25 1,000 0,01342987 0,09133304 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01342987 0,09099725 ! cellular component disassembly GO:0022411 26 25 1,000 0,01342987 0,09066393 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01342987 0,09033304 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 0,01342987 0,09000456 ! regulation of cell activation GO:0050865 71 71 2,000 0,01382434 0,09231253 ! secretion by cell GO:0032940 75 72 2,000 0,0143542 0,09550468 ! positive regulation of binding GO:0051099 27 26 1,000 0,01448347 0,09601809 ! glycolysis GO:0006096 26 26 1,000 0,01448347 0,09567394 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01448347 0,09533225 ! double-strand break repair GO:0006302 27 26 1,000 0,01448347 0,09499299 ! regulation of protein secretion GO:0050708 26 26 1,000 0,01448347 0,09465614 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01448347 0,09432166 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01448347 0,09398954 ! synapse organization GO:0050808 26 26 1,000 0,01448347 0,09365976 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01557169 0,10034486 ! learning or memory GO:0007611 28 27 1,000 0,01557169 0,09999523 ! activation of caspase activity GO:0006919 27 27 1,000 0,01557169 0,09964802 ! cell growth GO:0016049 27 27 1,000 0,01557169 0,09930322 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 0,01557169 0,0989608 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01557169 0,09862073 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! tRNA aminoacylation for protein translation GO:0006418 28 28 1,000 0,01669402 0,10536673 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! histone modification GO:0016570 28 28 1,000 0,01669402 0,10500712 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,01717595 0,10767101 ! regulation of protein modification process GO:0031399 79 78 2,000 0,01777497 0,11104836 ! microtubule-based movement GO:0007018 82 78 2,000 0,01777497 0,1106732 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01784994 0,11076578 ! glycerophospholipid biosynthetic process GO:0046474 30 29 1,000 0,01784994 0,11039408 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,01784994 0,11002487 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01784994 0,10965812 ! nuclear transport GO:0051169 79 79 2,000 0,01838559 0,11257357 GO:0006913|nucleocytoplasmic transport, ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 1,000 0,01903892 0,11618786 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01903892 0,11580441 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01903892 0,11542347 GO:0010863|positive regulation of phospholipase C activity, ! lymphocyte activation GO:0046649 82 81 2,000 0,01964172 0,11868752 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02026047 0,12202628 ! B cell activation GO:0042113 31 31 1,000 0,02026047 0,1216288 ! lipoprotein metabolic process GO:0042157 31 31 1,000 0,02026047 0,1212339 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,02026047 0,12084156 ! aging GO:0007568 32 31 1,000 0,02026047 0,12045175 ! glycerolipid biosynthetic process GO:0045017 32 31 1,000 0,02026047 0,12006444 ! muscle fiber development GO:0048747 32 32 1,000 0,02151407 0,1270847 ! glucose catabolic process GO:0006007 32 32 1,000 0,02151407 0,12667868 ! lipid modification GO:0030258 32 32 1,000 0,02151407 0,12627524 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,02151407 0,12587437 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,02151407 0,12547603 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,02151407 0,12508021 ! nuclear export GO:0051168 32 32 1,000 0,02151407 0,12468688 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02151407 0,12429601 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,02151407 0,12390758 ! maintenance of location GO:0051235 33 32 1,000 0,02151407 0,12352158 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,02279923 0,1304937 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02279923 0,1300897 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,02279923 0,12968819 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 0,02298608 0,13034876 ! organophosphate metabolic process GO:0019637 87 86 2,000 0,02298608 0,12994892 GO:0006644|phospholipid metabolic process, ! regulation of angiogenesis GO:0045765 35 34 1,000 0,02411545 0,13591672 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,02411545 0,13550234 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,02411545 0,13509048 ! positive regulation of transferase activity GO:0051347 91 88 2,000 0,02440557 0,13630143 GO:0033674|positive regulation of kinase activity, ! mesoderm development GO:0007498 35 35 1,000 0,02546224 0,14177316 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,02546224 0,14134613 ! regulation of immune effector process GO:0002697 35 35 1,000 0,02546224 0,14092167 ! regulation of Ras protein signal transduction GO:0046578 90 90 2,000 0,0258718 0,14275964 ! positive regulation of cell migration GO:0030335 36 36 1,000 0,02683913 0,14765529 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,02683913 0,14721584 GO:0045937|positive regulation of phosphate metabolic process, ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02683913 0,146779 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,02683913 0,14634474 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02683913 0,14591305 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,02824564 0,15310796 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 1,000 0,02824564 0,15265897 ! lung development GO:0030324 38 37 1,000 0,02824564 0,1522126 ! neurotransmitter transport GO:0006836 40 38 1,000 0,02968128 0,1594828 ! urogenital system development GO:0001655 38 38 1,000 0,02968128 0,15901918 ! hexose catabolic process GO:0019320 38 38 1,000 0,02968128 0,15855826 ! axon guidance GO:0007411 39 38 1,000 0,02968128 0,1581 ! regulation of neurological system process GO:0031644 38 38 1,000 0,02968128 0,15764438 ! respiratory tube development GO:0030323 40 39 1,000 0,0311456 0,16494636 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,0311456 0,16447374 ! respiratory system development GO:0060541 40 39 1,000 0,0311456 0,16400381 ! positive regulation of cell motion GO:0051272 39 39 1,000 0,0311456 0,16353657 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,0322029 0,16860778 ! DNA catabolic process GO:0006308 41 40 1,000 0,03263812 0,17040244 ! muscle organ development GO:0007517 102 100 2,000 0,03390172 0,17649963 ! hemopoiesis GO:0030097 104 100 2,000 0,03390172 0,17600245 ! phospholipid biosynthetic process GO:0008654 42 41 1,000 0,0341584 0,17683689 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 0,0341584 0,17634155 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,0341584 0,17584897 ! rRNA transcription GO:0009303 5 5 0,000 0,03511689 0,18027973 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03511689 0,17977895 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03511689 0,17928095 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03511689 0,1787857 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03511689 0,17829318 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03511689 0,17780336 ! reproductive cellular process GO:0048610 5 5 0,000 0,03511689 0,17731623 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03511689 0,17683176 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03511689 0,17634993 ! metencephalon development GO:0022037 5 5 0,000 0,03511689 0,17587072 ! water transport GO:0006833 5 5 0,000 0,03511689 0,1753941 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03511689 0,17492006 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03511689 0,17444858 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03511689 0,17397963 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03511689 0,1735132 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03511689 0,17304926 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03511689 0,1725878 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03511689 0,17212879 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03511689 0,17167221 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03511689 0,17121805 ! filopodium assembly GO:0046847 7 5 0,000 0,03511689 0,17076629 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03511689 0,1703169 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03511689 0,16986988 ! GTP metabolic process GO:0046039 5 5 0,000 0,03511689 0,16942519 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03511689 0,16898283 ! mRNA stabilization GO:0048255 5 5 0,000 0,03511689 0,16854277 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03511689 0,168105 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03511689 0,16766949 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03511689 0,16723624 ! social behavior GO:0035176 5 5 0,000 0,03511689 0,16680521 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03511689 0,16637641 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03511689 0,1659498 ! memory GO:0007613 5 5 0,000 0,03511689 0,16552538 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03511689 0,16510312 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03511689 0,16468301 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03511689 0,16426503 ! response to lipid GO:0033993 5 5 0,000 0,03511689 0,16384917 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03511689 0,16343541 ! hippocampus development GO:0021766 6 5 0,000 0,03511689 0,16302374 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03511689 0,16261413 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03511689 0,16220657 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03511689 0,16180106 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03511689 0,16139756 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03511689 0,16099608 ! heart looping GO:0001947 5 5 0,000 0,03511689 0,16059658 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03511689 0,16019907 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03511689 0,15980351 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03511689 0,15940991 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03511689 0,15901824 ! pH reduction GO:0045851 5 5 0,000 0,03511689 0,15862849 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03511689 0,15824064 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03511689 0,15785469 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03511689 0,15747062 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03511689 0,15708841 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03511689 0,15670805 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03511689 0,15632952 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03511689 0,15595283 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03511689 0,15557794 ! adrenal gland development GO:0030325 5 5 0,000 0,03511689 0,15520485 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03511689 0,15483355 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03511689 0,15446402 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03511689 0,15409625 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03511689 0,15373022 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03511689 0,15336593 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03511689 0,15300336 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03511689 0,15264251 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03511689 0,15228335 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03511689 0,15192588 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03511689 0,15157008 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03511689 0,15121594 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03511689 0,15086346 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03511689 0,15051261 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03511689 0,15016339 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03511689 0,14981579 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03511689 0,1494698 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03511689 0,1491254 ! response to ATP GO:0033198 5 5 0,000 0,03511689 0,14878258 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03511689 0,14844134 ! regulation of appetite GO:0032098 5 5 0,000 0,03511689 0,14810165 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03511689 0,14776352 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03511689 0,14742693 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03511689 0,14709187 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03511689 0,14675833 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03511689 0,1464263 ! receptor clustering GO:0043113 5 5 0,000 0,03511689 0,14609576 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03511689 0,14576672 ! fear response GO:0042596 5 5 0,000 0,03511689 0,14543915 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03511689 0,14511306 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03511689 0,14478842 ! retinol metabolic process GO:0042572 5 5 0,000 0,03511689 0,14446523 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03511689 0,14414348 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03511689 0,14382316 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03511689 0,14350426 ! parturition GO:0007567 5 5 0,000 0,03511689 0,14318678 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03511689 0,14287069 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03511689 0,142556 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03511689 0,14224269 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03511689 0,14193075 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03511689 0,14162018 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03511689 0,14131097 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03511689 0,1410031 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03511689 0,14069657 ! response to UV-B GO:0010224 5 5 0,000 0,03511689 0,14039137 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03511689 0,1400875 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03511689 0,13978493 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03511689 0,13948367 ! interaction with symbiont GO:0051702 5 5 0,000 0,03511689 0,13918371 ! cellular extravasation GO:0045123 5 5 0,000 0,03511689 0,13888503 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03511689 0,13858763 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03511689 0,1382915 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03511689 0,13799664 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03511689 0,13770303 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03511689 0,13741067 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03511689 0,13711954 ! response to amine stimulus GO:0014075 5 5 0,000 0,03511689 0,13682965 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03511689 0,13654098 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03511689 0,13625352 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03511689 0,13596728 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03511689 0,13568223 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03511689 0,13539837 ! neuron recognition GO:0008038 5 5 0,000 0,03511689 0,13511571 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03511689 0,13483422 ! decidualization GO:0046697 5 5 0,000 0,03511689 0,13455389 ! hair follicle maturation GO:0048820 5 5 0,000 0,03511689 0,13427474 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03511689 0,13399674 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03511689 0,13371988 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03511689 0,13344417 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03511689 0,1331696 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03511689 0,13289615 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03511689 0,13262382 ! postreplication repair GO:0006301 5 5 0,000 0,03511689 0,1323526 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03511689 0,1320825 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03511689 0,13181349 ! histone methylation GO:0016571 5 5 0,000 0,03511689 0,13154558 ! DNA methylation GO:0006306 5 5 0,000 0,03511689 0,13127875 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03511689 0,131013 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03511689 0,13074833 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03511689 0,13048472 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03511689 0,13022218 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03511689 0,12996069 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03511689 0,12970025 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03511689 0,12944085 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03511689 0,12918248 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03511689 0,12892515 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03511689 0,12866883 ! sterol catabolic process GO:0016127 5 5 0,000 0,03511689 0,12841354 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03511689 0,12815925 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03511689 0,12790597 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03511689 0,12765369 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03511689 0,12740241 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! zymogen activation GO:0031638 5 5 0,000 0,03511689 0,12715211 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03511689 0,12690279 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03511689 0,12665445 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03511689 0,12640708 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03511689 0,12616067 ! nucleosome positioning GO:0016584 5 5 0,000 0,03511689 0,12591522 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03511689 0,12567072 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03511689 0,12542718 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03511689 0,12518457 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03511689 0,1249429 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03511689 0,12470216 ! NADPH regeneration GO:0006740 5 5 0,000 0,03511689 0,12446235 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03511689 0,12422346 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03511689 0,12398549 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03511689 0,12374842 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03511689 0,12351226 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03511689 0,123277 ! sarcomere organization GO:0045214 5 5 0,000 0,03511689 0,12304263 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03511689 0,12280915 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03511689 0,12257656 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03511689 0,12234485 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03511689 0,12211401 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03511689 0,12188404 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03511689 0,12165493 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03511689 0,12142669 ! spleen development GO:0048536 5 5 0,000 0,03511689 0,12119929 ! male genitalia development GO:0030539 5 5 0,000 0,03511689 0,12097275 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03511689 0,12074706 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03511689 0,1205222 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03511689 0,12029818 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03511689 0,120075 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03511689 0,11985264 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03511689 0,1196311 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03511689 0,11941037 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03511689 0,11919047 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03511689 0,11897137 ! ATP catabolic process GO:0006200 5 5 0,000 0,03511689 0,11875307 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03511689 0,11853557 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03511689 0,11831887 ! blastocyst formation GO:0001825 5 5 0,000 0,03511689 0,11810296 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03511689 0,11788784 ! embryonic gut development GO:0048566 5 5 0,000 0,03511689 0,1176735 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03511689 0,11745993 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03511689 0,11724714 ! activation of innate immune response GO:0002218 5 5 0,000 0,03511689 0,11703512 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,03511689 0,11682387 ! catecholamine transport GO:0051937 5 5 0,000 0,03511689 0,11661338 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03511689 0,11640364 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03511689 0,11619466 ! muscle adaptation GO:0043500 5 5 0,000 0,03511689 0,11598642 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03511689 0,11577893 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03511689 0,11557218 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03511689 0,11536617 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03511689 0,1151609 ! defense response to fungus GO:0050832 5 5 0,000 0,03511689 0,11495635 ! lysogeny GO:0030069 5 5 0,000 0,03511689 0,11475252 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03511689 0,11454942 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03511689 0,11434704 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03511689 0,11414537 ! response to nicotine GO:0035094 5 5 0,000 0,03511689 0,11394441 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03511689 0,11374415 ! mitochondrion localization GO:0051646 5 5 0,000 0,03511689 0,1135446 ! nucleus localization GO:0051647 5 5 0,000 0,03511689 0,11334575 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03511689 0,11314759 ! protein ubiquitination GO:0016567 43 42 1,000 0,03570598 0,11484488 ! negative regulation of ligase activity GO:0051352 43 42 1,000 0,03570598 0,1146448 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 1,000 0,03570598 0,11444541 ! reproductive structure development GO:0048608 43 43 1,000 0,0372804 0,11928434 ! alcohol catabolic process GO:0046164 43 43 1,000 0,0372804 0,11907761 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,0372804 0,11887159 ! protein import into nucleus GO:0006606 44 44 1,000 0,03888123 0,12376184 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,04050803 0,12871775 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,04050803 0,1284962 ! regulation of DNA binding GO:0051101 47 45 1,000 0,04050803 0,12827542 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,04050803 0,12805539 ! nuclear import GO:0051170 45 45 1,000 0,04050803 0,12783612 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04199387 0,13229864 ! axon extension GO:0048675 7 6 0,000 0,04199387 0,13207288 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04199387 0,13184788 ! tRNA modification GO:0006400 6 6 0,000 0,04199387 0,13162365 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04199387 0,13140018 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04199387 0,13117747 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04199387 0,13095551 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04199387 0,1307343 ! virus-host interaction GO:0019048 6 6 0,000 0,04199387 0,13051384 ! regulation of S phase GO:0033261 6 6 0,000 0,04199387 0,13029412 ! myotube differentiation GO:0014902 6 6 0,000 0,04199387 0,13007514 ! bone remodeling GO:0046849 6 6 0,000 0,04199387 0,12985689 ! N-glycan processing GO:0006491 6 6 0,000 0,04199387 0,12963937 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,04199387 0,12942259 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04199387 0,12920652 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04199387 0,12899118 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04199387 0,12877655 ! RNA methylation GO:0001510 6 6 0,000 0,04199387 0,12856264 ! cartilage condensation GO:0001502 7 6 0,000 0,04199387 0,12834943 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04199387 0,12813693 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,04199387 0,12792514 ! artery development GO:0060840 6 6 0,000 0,04199387 0,12771404 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04199387 0,12750364 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04199387 0,12729393 ! androgen metabolic process GO:0008209 6 6 0,000 0,04199387 0,1270849 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04199387 0,12687657 ! limbic system development GO:0021761 7 6 0,000 0,04199387 0,12666891 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04199387 0,12646194 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04199387 0,12625564 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04199387 0,12605001 ! pathogenesis GO:0009405 6 6 0,000 0,04199387 0,12584505 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04199387 0,12564076 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04199387 0,12543713 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04199387 0,12523415 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04199387 0,12503184 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04199387 0,12483017 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04199387 0,12462916 ! arginine metabolic process GO:0006525 6 6 0,000 0,04199387 0,12442879 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04199387 0,12422906 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04199387 0,12402998 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04199387 0,12383153 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04199387 0,12363372 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04199387 0,12343653 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04199387 0,12323998 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04199387 0,12304405 ! V(D)J recombination GO:0033151 6 6 0,000 0,04199387 0,12284874 ! focal adhesion formation GO:0048041 7 6 0,000 0,04199387 0,12265405 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04199387 0,12245998 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04199387 0,12226652 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04199387 0,12207367 ! regulation of heart rate GO:0002027 6 6 0,000 0,04199387 0,12188143 ! lipid digestion GO:0044241 6 6 0,000 0,04199387 0,12168979 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04199387 0,12149875 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04199387 0,12130832 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04199387 0,12111848 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04199387 0,12092923 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04199387 0,12074057 ! ruffle organization GO:0031529 6 6 0,000 0,04199387 0,1205525 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04199387 0,12036502 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04199387 0,12017812 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04199387 0,11999179 ! L-amino acid transport GO:0015807 6 6 0,000 0,04199387 0,11980605 ! bone mineralization GO:0030282 6 6 0,000 0,04199387 0,11962088 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04199387 0,11943628 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04199387 0,11925224 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04199387 0,11906878 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,04199387 0,11888588 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04199387 0,11870354 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04199387 0,11852176 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04199387 0,11834053 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04199387 0,11815986 ! regulation of organ growth GO:0046620 6 6 0,000 0,04199387 0,11797974 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04199387 0,11780016 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04199387 0,11762113 ! response to dsRNA GO:0043331 6 6 0,000 0,04199387 0,11744265 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04199387 0,11726471 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04199387 0,1170873 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04199387 0,11691043 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04199387 0,1167341 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04199387 0,11655829 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04199387 0,11638302 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04199387 0,11620827 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04199387 0,11603404 ! erythrocyte development GO:0048821 6 6 0,000 0,04199387 0,11586034 ! renal water homeostasis GO:0003091 6 6 0,000 0,04199387 0,11568716 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04199387 0,11551449 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04199387 0,11534233 ! ribosome assembly GO:0042255 6 6 0,000 0,04199387 0,11517069 ! diencephalon development GO:0021536 6 6 0,000 0,04199387 0,11499956 ! fucose catabolic process GO:0019317 6 6 0,000 0,04199387 0,11482894 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04199387 0,11465882 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04199387 0,11448921 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04199387 0,1143201 ! regulation of cell division GO:0051302 6 6 0,000 0,04199387 0,11415148 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04199387 0,11398337 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04199387 0,11381575 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04199387 0,11364861 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04199387 0,11348197 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04199387 0,11331582 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04199387 0,11315016 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04199387 0,11298497 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04199387 0,11282027 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04199387 0,11265605 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04199387 0,11249231 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04199387 0,11232904 ! thymus development GO:0048538 6 6 0,000 0,04199387 0,11216624 ! lymph node development GO:0048535 6 6 0,000 0,04199387 0,11200392 ! organic cation transport GO:0015695 6 6 0,000 0,04199387 0,11184206 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04199387 0,11168067 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04199387 0,11151975 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04199387 0,11135929 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04199387 0,11119929 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04199387 0,11103975 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04199387 0,11088067 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04199387 0,11072204 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04199387 0,11056387 ! alditol metabolic process GO:0019400 6 6 0,000 0,04199387 0,11040614 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04199387 0,11024887 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04199387 0,11009204 ! maternal placenta development GO:0001893 6 6 0,000 0,04199387 0,10993566 ! regulation of embryonic development GO:0045995 6 6 0,000 0,04199387 0,10977973 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04199387 0,10962423 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,04216036 0,10990316 ! regulation of membrane potential GO:0042391 46 46 1,000 0,04216036 0,10974793 ! sex differentiation GO:0007548 47 47 1,000 0,04383779 0,11395351 ! protein localization in nucleus GO:0034504 48 48 1,000 0,04553989 0,1182113 ! ossification GO:0001503 50 49 1,000 0,04726626 0,12251999 GO:0060348|bone development, ! respiratory burst GO:0045730 7 7 0,000 0,04882284 0,12637709 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04882284 0,12619984 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04882284 0,12602309 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04882284 0,12584684 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04882284 0,12567107 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04882284 0,1254958 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04882284 0,12532101 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04882284 0,12514671 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04882284 0,1249729 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04882284 0,12479957 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04882284 0,12462671 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04882284 0,12445434 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04882284 0,12428244 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04882284 0,12411102 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04882284 0,12394007 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04882284 0,12376958 ! axis specification GO:0009798 7 7 0,000 0,04882284 0,12359957 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04882284 0,12343002 ! visual behavior GO:0007632 7 7 0,000 0,04882284 0,12326094 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04882284 0,12309232 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04882284 0,12292416 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04882284 0,12275646 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04882284 0,12258922 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04882284 0,12242243 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04882284 0,1222561 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04882284 0,12209021 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04882284 0,12192478 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04882284 0,12175979 ! digestive system development GO:0055123 7 7 0,000 0,04882284 0,12159525 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04882284 0,12143116 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04882284 0,1212675 ! protein targeting to ER GO:0045047 8 7 0,000 0,04882284 0,12110429 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04882284 0,12094152 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04882284 0,12077918 ! endoderm development GO:0007492 7 7 0,000 0,04882284 0,12061728 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04882284 0,12045581 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04882284 0,12029477 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,04882284 0,12013416 ! response to hexose stimulus GO:0009746 7 7 0,000 0,04882284 0,11997398 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04882284 0,11981423 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04882284 0,1196549 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04882284 0,119496 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04882284 0,11933752 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04882284 0,11917945 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04882284 0,11902181 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04882284 0,11886458 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04882284 0,11870777 ! UV protection GO:0009650 7 7 0,000 0,04882284 0,11855137 ! DNA integration GO:0015074 7 7 0,000 0,04882284 0,11839538 ! myofibril assembly GO:0030239 7 7 0,000 0,04882284 0,1182398 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04882284 0,11808463 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04882284 0,11792987 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04882284 0,11777551 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04882284 0,11762155 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04882284 0,117468 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04882284 0,11731485 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04882284 0,11716209 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04882284 0,11700974 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04882284 0,11685778 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04882284 0,11670621 ! eating behavior GO:0042755 7 7 0,000 0,04882284 0,11655504 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04882284 0,11640425 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04882284 0,11625386 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04882284 0,11610386 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04882284 0,11595424 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04882284 0,115805 ! cranial nerve development GO:0021545 7 7 0,000 0,04882284 0,11565615 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04882284 0,11550769 ! induction of an organ GO:0001759 7 7 0,000 0,04882284 0,1153596 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04882284 0,11521189 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04882284 0,11506456 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04882284 0,11491761 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04882284 0,11477103 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04882284 0,11462483 ! platelet activation GO:0030168 8 7 0,000 0,04882284 0,11447899 ! natural killer cell activation GO:0030101 7 7 0,000 0,04882284 0,11433353 ! NADP metabolic process GO:0006739 7 7 0,000 0,04882284 0,11418844 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04882284 0,11404371 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04882284 0,11389935 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04882284 0,11375536 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04882284 0,11361173 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04882284 0,11346846 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04882284 0,11332555 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04882284 0,113183 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04882284 0,11304081 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04882284 0,11289898 ! cell-cell recognition GO:0009988 8 7 0,000 0,04882284 0,1127575 ! hormone catabolic process GO:0042447 7 7 0,000 0,04882284 0,11261638 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04882284 0,11247561 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04882284 0,11233519 ! oxygen transport GO:0015671 7 7 0,000 0,04882284 0,11219512 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04882284 0,1120554 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,04882284 0,11191603 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04882284 0,111777 ! regulation of axon extension GO:0030516 7 7 0,000 0,04882284 0,11163832 ! cell killing GO:0001906 7 7 0,000 0,04882284 0,11149998 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04882284 0,11136199 ! adult feeding behavior GO:0008343 7 7 0,000 0,04882284 0,11122434 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04882284 0,11108702 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04882284 0,11095005 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04882284 0,11081341 ! response to cold GO:0009409 7 7 0,000 0,04882284 0,11067711 ! RNA transport GO:0050658 50 50 1,000 0,04901646 0,11097953 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,04901646 0,11084336 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,04901646 0,11070752 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,0507901 0,11457301 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,0507901 0,11443294 ! RNA localization GO:0006403 52 52 1,000 0,05258675 0,11833624 ! cholesterol metabolic process GO:0008203 52 52 1,000 0,05258675 0,11819193 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,05258675 0,11804797 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,05258675 0,11790436 ! tRNA metabolic process GO:0006399 53 53 1,000 0,05440602 0,12183512 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,05440602 0,12168726 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,05440602 0,12153976 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05560411 0,12406583 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05560411 0,12391581 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05560411 0,12376615 ! positive regulation of translation GO:0045727 8 8 0,000 0,05560411 0,12361685 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05560411 0,12346792 ! superoxide anion generation GO:0042554 8 8 0,000 0,05560411 0,12331934 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05560411 0,12317112 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05560411 0,12302326 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05560411 0,12287575 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05560411 0,12272859 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05560411 0,12258178 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05560411 0,12243533 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,05560411 0,12228923 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05560411 0,12214347 ! zinc ion transport GO:0006829 8 8 0,000 0,05560411 0,12199806 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05560411 0,121853 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05560411 0,12170828 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05560411 0,1215639 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05560411 0,12141987 ! lipid localization GO:0010876 8 8 0,000 0,05560411 0,12127618 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05560411 0,12113283 ! response to cAMP GO:0051591 8 8 0,000 0,05560411 0,12098981 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05560411 0,12084714 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05560411 0,1207048 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05560411 0,12056279 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05560411 0,12042112 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05560411 0,12027978 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05560411 0,12013877 ! sensory perception of taste GO:0050909 8 8 0,000 0,05560411 0,11999809 ! organelle fusion GO:0048284 8 8 0,000 0,05560411 0,11985774 ! pancreas development GO:0031016 8 8 0,000 0,05560411 0,11971772 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05560411 0,11957803 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05560411 0,11943866 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05560411 0,11929962 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05560411 0,1191609 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05560411 0,1190225 ! sperm motility GO:0030317 8 8 0,000 0,05560411 0,11888442 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05560411 0,11874666 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05560411 0,11860923 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05560411 0,11847211 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05560411 0,1183353 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05560411 0,11819881 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05560411 0,11806264 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05560411 0,11792678 ! Golgi organization GO:0007030 8 8 0,000 0,05560411 0,11779123 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05560411 0,117656 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,05560411 0,11752107 ! mannose metabolic process GO:0006013 9 8 0,000 0,05560411 0,11738645 ! NAD metabolic process GO:0019674 8 8 0,000 0,05560411 0,11725214 ! sex determination GO:0007530 8 8 0,000 0,05560411 0,11711814 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05560411 0,11698444 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05560411 0,11685105 ! response to fungus GO:0009620 8 8 0,000 0,05560411 0,11671796 ! stem cell differentiation GO:0048863 8 8 0,000 0,05560411 0,11658518 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05560411 0,1164527 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05560411 0,11632051 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05560411 0,11618863 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05560411 0,11605705 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05560411 0,11592576 ! vasoconstriction GO:0042310 8 8 0,000 0,05560411 0,11579477 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05560411 0,11566408 ! muscle cell development GO:0055001 8 8 0,000 0,05560411 0,11553368 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05560411 0,11540357 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05560411 0,11527376 ! sensory perception of pain GO:0019233 8 8 0,000 0,05560411 0,11514424 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05560411 0,11501501 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05560411 0,11488607 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05560411 0,11475742 ! chromatin silencing GO:0006342 8 8 0,000 0,05560411 0,11462905 ! tissue regeneration GO:0042246 8 8 0,000 0,05560411 0,11450097 ! salivary gland development GO:0007431 8 8 0,000 0,05560411 0,11437318 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05560411 0,11424568 ! water homeostasis GO:0030104 8 8 0,000 0,05560411 0,11411845 ! cofactor transport GO:0051181 8 8 0,000 0,05560411 0,11399151 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05560411 0,11386486 ! acid secretion GO:0046717 8 8 0,000 0,05560411 0,11373848 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,05560411 0,11361239 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05560411 0,11348657 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05560411 0,11336103 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05560411 0,11323577 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05560411 0,11311079 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05560411 0,11298608 ! regulation of RNA stability GO:0043487 8 8 0,000 0,05560411 0,11286164 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05560411 0,11273748 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,05560411 0,1126136 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05560411 0,11248998 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05560411 0,11236664 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05560411 0,11224356 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05560411 0,11212076 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05560411 0,11199822 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05560411 0,11187595 ! developmental induction GO:0031128 8 8 0,000 0,05560411 0,11175395 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05560411 0,11163221 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05560411 0,11151074 ! actin filament polymerization GO:0030041 9 8 0,000 0,05560411 0,11138953 ! peptide hormone processing GO:0016486 8 8 0,000 0,05560411 0,11126859 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05560411 0,11114791 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05560411 0,11102749 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,05624752 0,11219067 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,05811084 0,11578192 ! in utero embryonic development GO:0001701 55 55 1,000 0,05811084 0,11565689 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,05811084 0,11553212 ! reproductive developmental process GO:0003006 56 56 1,000 0,0599956 0,11915074 ! extracellular structure organization GO:0043062 56 56 1,000 0,0599956 0,11902248 ! regulation of binding GO:0051098 60 57 1,000 0,06190141 0,12267128 ! lactation GO:0007595 10 9 0,000 0,06233801 0,12340382 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06233801 0,12327142 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06233801 0,12313929 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06233801 0,12300745 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06233801 0,12287589 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06233801 0,12274461 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,06233801 0,12261362 ! viral genome replication GO:0019079 9 9 0,000 0,06233801 0,1224829 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06233801 0,12235246 ! copper ion transport GO:0006825 9 9 0,000 0,06233801 0,1222223 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06233801 0,12209241 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06233801 0,1219628 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06233801 0,12183347 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06233801 0,12170441 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06233801 0,12157562 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06233801 0,1214471 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06233801 0,12131886 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06233801 0,12119089 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06233801 0,12106318 ! response to alkaloid GO:0043279 10 9 0,000 0,06233801 0,12093575 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06233801 0,12080858 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06233801 0,12068168 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,06233801 0,12055505 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06233801 0,12042868 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06233801 0,12030258 ! response to ethanol GO:0045471 9 9 0,000 0,06233801 0,12017674 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06233801 0,12005116 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,06233801 0,11992585 ! methionine metabolic process GO:0006555 9 9 0,000 0,06233801 0,11980079 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06233801 0,119676 ! cerebral cortex development GO:0021987 9 9 0,000 0,06233801 0,11955147 ! response to osmotic stress GO:0006970 9 9 0,000 0,06233801 0,11942719 ! pigmentation during development GO:0048066 9 9 0,000 0,06233801 0,11930318 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06233801 0,11917942 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06233801 0,11905592 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06233801 0,11893267 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06233801 0,11880968 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06233801 0,11868694 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,06233801 0,11856446 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,06233801 0,11844223 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,06233801 0,11832025 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06233801 0,11819852 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06233801 0,11807704 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06233801 0,11795581 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06233801 0,11783483 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,06233801 0,1177141 ! DNA replication initiation GO:0006270 9 9 0,000 0,06233801 0,11759361 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06233801 0,11747337 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,06233801 0,11735338 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06233801 0,11723363 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06233801 0,11711413 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06233801 0,11699487 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06233801 0,11687585 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06233801 0,11675707 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,06233801 0,11663854 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,06233801 0,11652024 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06233801 0,11640219 ! collagen catabolic process GO:0030574 9 9 0,000 0,06233801 0,11628437 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06233801 0,11616679 ! purine base metabolic process GO:0006144 9 9 0,000 0,06233801 0,11604945 ! gas transport GO:0015669 9 9 0,000 0,06233801 0,11593235 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06233801 0,11581548 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06233801 0,11569885 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06233801 0,11558245 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,06233801 0,11546629 ! defense response to virus GO:0051607 9 9 0,000 0,06233801 0,11535036 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06233801 0,11523466 ! actin filament-based movement GO:0030048 9 9 0,000 0,06233801 0,1151192 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06233801 0,11500396 ! sterol metabolic process GO:0016125 59 59 1,000 0,06577465 0,12122269 ! protein localization in organelle GO:0033365 59 59 1,000 0,06577465 0,12110159 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,06774134 0,1245981 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06902488 0,12683235 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,06902488 0,12670602 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06902488 0,12657995 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,06902488 0,12645412 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06902488 0,12632855 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06902488 0,12620322 ! neuron maturation GO:0042551 10 10 0,000 0,06902488 0,12607815 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06902488 0,12595332 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06902488 0,12582873 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06902488 0,1257044 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06902488 0,1255803 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,06902488 0,12545646 ! hormone secretion GO:0046879 10 10 0,000 0,06902488 0,12533286 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06902488 0,1252095 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06902488 0,12508638 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,06902488 0,12496351 ! inositol metabolic process GO:0006020 10 10 0,000 0,06902488 0,12484087 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06902488 0,12471848 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06902488 0,12459633 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06902488 0,12447441 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06902488 0,12435274 ! glial cell development GO:0021782 10 10 0,000 0,06902488 0,1242313 ! phototransduction GO:0007602 11 10 0,000 0,06902488 0,1241101 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06902488 0,12398913 ! fat cell differentiation GO:0045444 10 10 0,000 0,06902488 0,1238684 ! myoblast differentiation GO:0045445 10 10 0,000 0,06902488 0,12374791 ! centrosome cycle GO:0007098 10 10 0,000 0,06902488 0,12362765 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06902488 0,12350762 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06902488 0,12338783 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06902488 0,12326826 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06902488 0,12314893 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,06902488 0,12302983 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06902488 0,12291096 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06902488 0,12279232 ! plasma membrane organization GO:0007009 10 10 0,000 0,06902488 0,12267391 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06902488 0,12255573 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,06902488 0,12243778 ! lysosomal transport GO:0007041 10 10 0,000 0,06902488 0,12232005 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06902488 0,12220254 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06902488 0,12208527 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06902488 0,12196822 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06902488 0,12185139 ! exocrine system development GO:0035272 10 10 0,000 0,06902488 0,12173478 ! embryo implantation GO:0007566 11 10 0,000 0,06902488 0,1216184 ! regulation of protein binding GO:0043393 11 10 0,000 0,06902488 0,12150224 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06902488 0,12138631 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06902488 0,12127059 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06902488 0,12115509 ! protein export from nucleus GO:0006611 10 10 0,000 0,06902488 0,12103982 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06902488 0,12092476 ! cytolysis GO:0019835 10 10 0,000 0,06902488 0,12080992 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06902488 0,1206953 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06902488 0,1205809 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06902488 0,12046671 ! histone deacetylation GO:0016575 10 10 0,000 0,06902488 0,12035274 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06902488 0,12023899 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06902488 0,12012545 ! gland morphogenesis GO:0022612 10 10 0,000 0,06902488 0,12001212 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06902488 0,11989901 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06902488 0,11978611 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06902488 0,11967342 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06902488 0,11956095 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06902488 0,11944868 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06902488 0,11933663 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06902488 0,11922479 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06902488 0,11911315 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06902488 0,11900173 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06902488 0,11889051 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06902488 0,1187795 ! nerve development GO:0021675 10 10 0,000 0,06902488 0,1186687 ! gut development GO:0048565 10 10 0,000 0,06902488 0,11855811 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06902488 0,11844772 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,06902488 0,11833753 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06902488 0,11822755 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06902488 0,11811778 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,06972759 0,11920959 ! lipid transport GO:0006869 62 62 1,000 0,07173301 0,12252451 ! axonogenesis GO:0007409 66 62 1,000 0,07173301 0,12241106 ! protein import GO:0017038 62 62 1,000 0,07173301 0,12229782 ! regulation of secretion GO:0051046 65 63 1,000 0,07375726 0,12563275 ! glucose metabolic process GO:0006006 63 63 1,000 0,07375726 0,12551675 ! protein secretion GO:0009306 11 11 0,000 0,07566502 0,12864449 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07566502 0,12852593 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,07566502 0,12840758 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07566502 0,12828945 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07566502 0,12817154 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07566502 0,12805384 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07566502 0,12793636 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,07566502 0,12781909 ! signal complex assembly GO:0007172 11 11 0,000 0,07566502 0,12770204 ! endothelial cell migration GO:0043542 11 11 0,000 0,07566502 0,12758521 ! peroxisomal transport GO:0043574 11 11 0,000 0,07566502 0,12746858 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07566502 0,12735218 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,07566502 0,12723598 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07566502 0,12711999 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07566502 0,12700422 ! T cell proliferation GO:0042098 11 11 0,000 0,07566502 0,12688865 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,07566502 0,1267733 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07566502 0,12665816 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,07566502 0,12654322 ! spinal cord development GO:0021510 11 11 0,000 0,07566502 0,1264285 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07566502 0,12631398 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07566502 0,12619967 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07566502 0,12608556 ! digestive system process GO:0022600 11 11 0,000 0,07566502 0,12597166 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07566502 0,12585797 ! fucose metabolic process GO:0006004 11 11 0,000 0,07566502 0,12574448 ! membrane budding GO:0006900 11 11 0,000 0,07566502 0,1256312 ! monoamine transport GO:0015844 11 11 0,000 0,07566502 0,12551812 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07566502 0,12540524 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07566502 0,12529257 ! body fluid secretion GO:0007589 11 11 0,000 0,07566502 0,1251801 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07566502 0,12506783 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07566502 0,12495576 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,07566502 0,1248439 ! membrane depolarization GO:0051899 11 11 0,000 0,07566502 0,12473223 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07566502 0,12462076 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07566502 0,12450949 ! oogenesis GO:0048477 11 11 0,000 0,07566502 0,12439842 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,07566502 0,12428755 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07566502 0,12417688 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,07566502 0,1240664 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,07566502 0,12395612 ! muscle maintenance GO:0046716 12 11 0,000 0,07566502 0,12384603 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07566502 0,12373614 ! hindbrain development GO:0030902 11 11 0,000 0,07566502 0,12362645 ! steroid catabolic process GO:0006706 11 11 0,000 0,07566502 0,12351695 ! endocrine process GO:0050886 11 11 0,000 0,07566502 0,12340764 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07566502 0,12329852 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07566502 0,1231896 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07566502 0,12308088 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07566502 0,12297234 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,07579998 0,12308314 ! angiogenesis GO:0001525 65 64 1,000 0,07579998 0,1229748 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,07993942 0,12957638 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,07993942 0,12946252 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,08203544 0,1327404 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 1,000 0,08203544 0,13262396 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,08203544 0,13250772 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,08203544 0,13239169 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,08225876 0,13263596 ! translational initiation GO:0006413 12 12 0,000 0,08225876 0,13252002 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,08225876 0,13240428 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,08225876 0,13228874 ! initiation of viral infection GO:0019059 12 12 0,000 0,08225876 0,13217341 ! iron ion transport GO:0006826 13 12 0,000 0,08225876 0,13205827 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08225876 0,13194334 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,08225876 0,13182861 ! collagen metabolic process GO:0032963 12 12 0,000 0,08225876 0,13171407 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08225876 0,13159974 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,08225876 0,1314856 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08225876 0,13137166 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08225876 0,13125792 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08225876 0,13114438 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08225876 0,13103103 GO:0042744|hydrogen peroxide catabolic process, ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08225876 0,13091787 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,08225876 0,13080492 ! retinoid metabolic process GO:0001523 12 12 0,000 0,08225876 0,13069215 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08225876 0,13057959 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08225876 0,13046721 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08225876 0,13035503 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,08225876 0,13024304 ! acute-phase response GO:0006953 12 12 0,000 0,08225876 0,13013124 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08225876 0,13001964 ! vacuolar transport GO:0007034 12 12 0,000 0,08225876 0,12990822 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08225876 0,129797 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08225876 0,12968597 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08225876 0,12957513 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08225876 0,12946447 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,08225876 0,12935401 ! male gonad development GO:0008584 12 12 0,000 0,08225876 0,12924373 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08225876 0,12913364 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08225876 0,12902374 ! renal system process GO:0003014 12 12 0,000 0,08225876 0,12891403 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08225876 0,1288045 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08225876 0,12869516 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,08225876 0,128586 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08225876 0,12847703 ! pallium development GO:0021543 13 12 0,000 0,08225876 0,12836825 ! cell fate determination GO:0001709 12 12 0,000 0,08225876 0,12825964 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,08225876 0,12815122 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,08225876 0,12804299 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,08225876 0,12793494 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08225876 0,12782706 ! detection of light stimulus GO:0009583 13 12 0,000 0,08225876 0,12771938 ! synaptogenesis GO:0007416 12 12 0,000 0,08225876 0,12761187 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08225876 0,12750454 ! hormone transport GO:0009914 12 12 0,000 0,08225876 0,12739739 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08225876 0,12729043 ! spermatid differentiation GO:0048515 13 12 0,000 0,08225876 0,12718364 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,08225876 0,12707703 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08225876 0,1269706 ! neural tube closure GO:0001843 13 12 0,000 0,08225876 0,12686435 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,08225876 0,12675828 ! regulation of translation GO:0006417 69 69 1,000 0,08627838 0,13284131 ! regionalization GO:0003002 70 69 1,000 0,08627838 0,13273043 ! response to nutrient levels GO:0031667 69 69 1,000 0,08627838 0,13261973 ! cell part morphogenesis GO:0032990 75 70 1,000 0,08842463 0,13580549 ! growth GO:0040007 70 70 1,000 0,08842463 0,13569242 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,08880642 0,13616492 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,08880642 0,13605173 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08880642 0,13593873 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08880642 0,13582592 ! phenol metabolic process GO:0018958 13 13 0,000 0,08880642 0,13571329 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,08880642 0,13560086 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08880642 0,1354886 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08880642 0,13537654 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08880642 0,13526466 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08880642 0,13515296 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,08880642 0,13504145 ! regeneration GO:0031099 13 13 0,000 0,08880642 0,13493012 ! keratinization GO:0031424 13 13 0,000 0,08880642 0,13481897 ! post-embryonic development GO:0009791 14 13 0,000 0,08880642 0,13470801 ! patterning of blood vessels GO:0001569 13 13 0,000 0,08880642 0,13459723 ! vasculogenesis GO:0001570 13 13 0,000 0,08880642 0,13448663 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,08880642 0,13437622 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08880642 0,13426598 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,08880642 0,13415593 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,08880642 0,13404606 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,08880642 0,13393636 ! autophagy GO:0006914 13 13 0,000 0,08880642 0,13382685 ! receptor metabolic process GO:0043112 14 13 0,000 0,08880642 0,13371751 ! actin filament bundle formation GO:0051017 13 13 0,000 0,08880642 0,13360835 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,08880642 0,13349937 ! ureteric bud development GO:0001657 13 13 0,000 0,08880642 0,13339057 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,08880642 0,13328195 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,08880642 0,1331735 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,08880642 0,13306523 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08880642 0,13295714 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08880642 0,13284922 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,08880642 0,13274147 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,08880642 0,1326339 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,08880642 0,1325265 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08880642 0,13241928 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08880642 0,13231223 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,08880642 0,13220536 ! vasodilation GO:0042311 14 13 0,000 0,08880642 0,13209865 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08880642 0,13199212 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,08880642 0,13188576 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08880642 0,13177958 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,08880642 0,13167356 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,08880642 0,13156771 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08880642 0,13146203 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08880642 0,13135653 ! immunoglobulin production GO:0002377 13 13 0,000 0,08880642 0,13125119 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08880642 0,13114602 ! cell-cell junction organization GO:0045216 13 13 0,000 0,08880642 0,13104102 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08880642 0,13093619 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,08880642 0,13083152 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,08880642 0,13072702 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08880642 0,13062269 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08880642 0,13051853 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08880642 0,13041453 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08880642 0,1303107 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08880642 0,13020703 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,08880642 0,13010352 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08880642 0,13000019 ! blastocyst development GO:0001824 13 13 0,000 0,08880642 0,12989701 ! telomere organization GO:0032200 13 13 0,000 0,08880642 0,129794 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08880642 0,12969115 ! regulation of amine transport GO:0051952 13 13 0,000 0,08880642 0,12958847 ! tissue homeostasis GO:0001894 13 13 0,000 0,08880642 0,12948594 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08880642 0,12938358 ! regulation of cell migration GO:0030334 71 71 1,000 0,09058696 0,13187343 ! ribosome biogenesis GO:0042254 71 71 1,000 0,09058696 0,13176934 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,09058696 0,13166543 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,09276503 0,13472495 ! regulation of cytokine production GO:0001817 72 72 1,000 0,09276503 0,13461887 ! neuron fate commitment GO:0048663 14 14 0,000 0,09530831 0,1382008 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,09530831 0,13809215 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,09530831 0,13798368 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,09530831 0,13787537 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,09530831 0,13776723 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,09530831 0,13765926 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,09530831 0,13755146 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,09530831 0,13744383 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,09530831 0,13733637 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,09530831 0,13722908 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,09530831 0,13712195 ! vesicle docking GO:0048278 14 14 0,000 0,09530831 0,13701499 ! superoxide metabolic process GO:0006801 15 14 0,000 0,09530831 0,1369082 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,09530831 0,13680157 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,09530831 0,13669511 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,09530831 0,13658882 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,09530831 0,13648269 ! hair cycle GO:0042633 14 14 0,000 0,09530831 0,13637672 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,09530831 0,13627092 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,09530831 0,13616529 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,09530831 0,13605981 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,09530831 0,1359545 ! lysosome organization GO:0007040 14 14 0,000 0,09530831 0,13584936 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,09530831 0,13574437 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,09530831 0,13563955 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,09530831 0,13553489 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,09530831 0,13543039 ! primary neural tube formation GO:0014020 15 14 0,000 0,09530831 0,13532605 ! regulation of behavior GO:0050795 14 14 0,000 0,09530831 0,13522188 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,09530831 0,13511786 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,09530831 0,135014 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,09530831 0,13491031 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,09530831 0,13480677 ! formation of primary germ layer GO:0001704 14 14 0,000 0,09530831 0,13470339 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,09530831 0,13460017 ! collagen fibril organization GO:0030199 14 14 0,000 0,09530831 0,1344971 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,09530831 0,1343942 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,09530831 0,13429145 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,09530831 0,13418886 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,09530831 0,13408643 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,09530831 0,13398415 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,09530831 0,13388203 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,09530831 0,13378006 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,09530831 0,13367825 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,10162846 0,14243442 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,10176475 0,14251704 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,10176475 0,14240883 ! positive regulation of ossification GO:0045778 15 15 0,000 0,10176475 0,14230078 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,10176475 0,1421929 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,10176475 0,14208517 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,10176475 0,14197762 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,10176475 0,14187022 ! response to vitamin GO:0033273 15 15 0,000 0,10176475 0,14176299 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,10176475 0,14165591 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,10176475 0,141549 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,10176475 0,14144226 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,10176475 0,14133567 ! ovarian follicle development GO:0001541 15 15 0,000 0,10176475 0,14122924 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,10176475 0,14112297 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,10176475 0,14101687 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,10176475 0,14091092 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,10176475 0,14080513 ! heme metabolic process GO:0042168 15 15 0,000 0,10176475 0,1406995 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,10176475 0,14059403 ! chromosome condensation GO:0030261 15 15 0,000 0,10176475 0,14048871 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,10176475 0,14038356 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,10176475 0,14027856 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,10176475 0,14017372 GO:0030500|regulation of bone mineralization, ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,10176475 0,14006903 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,10176475 0,1399645 ! glutathione metabolic process GO:0006749 16 15 0,000 0,10176475 0,13986013 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,10176475 0,13975591 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,10176475 0,13965185 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,10176475 0,13954794 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,10176475 0,13944419 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,10176475 0,13934059 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,10176475 0,13923714 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,10176475 0,13913385 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,10614647 0,145017 ! regulation of immune response GO:0050776 78 78 1,000 0,10614647 0,14490958 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,10817604 0,14757102 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,10817604 0,14746187 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,10817604 0,14735288 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,10817604 0,14724405 ! learning GO:0007612 16 16 0,000 0,10817604 0,14713538 ! circadian rhythm GO:0007623 16 16 0,000 0,10817604 0,14702688 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,10817604 0,14691853 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,10817604 0,14681034 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,10817604 0,14670231 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,10817604 0,14659444 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,10817604 0,14648673 ! vesicle targeting GO:0006903 17 16 0,000 0,10817604 0,14637918 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,10817604 0,14627179 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,10817604 0,14616455 ! iron ion homeostasis GO:0055072 16 16 0,000 0,10817604 0,14605747 ! positive regulation of cell development GO:0010720 16 16 0,000 0,10817604 0,14595054 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,10817604 0,14584378 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,10817604 0,14573717 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,10817604 0,14563071 ! cell fate specification GO:0001708 16 16 0,000 0,10817604 0,14552441 ! pentose metabolic process GO:0019321 16 16 0,000 0,10817604 0,14541827 ! fatty acid transport GO:0015908 16 16 0,000 0,10817604 0,14531228 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,10817604 0,14520644 ! cofactor catabolic process GO:0051187 16 16 0,000 0,10817604 0,14510076 ! polyol metabolic process GO:0019751 16 16 0,000 0,10817604 0,14499523 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,10817604 0,14488986 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,10817604 0,14478464 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,10817604 0,14467957 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,10817604 0,14457465 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,10817604 0,14446989 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,10817604 0,14436527 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,10817604 0,14426081 ! regulation of locomotion GO:0040012 79 79 1,000 0,10842597 0,14448956 ! regulation of cell motion GO:0051270 79 79 1,000 0,10842597 0,14438516 ! neuron projection development GO:0031175 85 80 1,000 0,11071874 0,14733187 ! tube development GO:0035295 83 81 1,000 0,11302449 0,15029158 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,1145425 0,15220031 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,1145425 0,15209065 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,1145425 0,15198116 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,1145425 0,15187182 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,1145425 0,15176264 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,1145425 0,15165361 ! leukocyte adhesion GO:0007159 17 17 0,000 0,1145425 0,15154474 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,1145425 0,15143603 ! sensory perception of smell GO:0007608 17 17 0,000 0,1145425 0,15132748 ! glucose transport GO:0015758 17 17 0,000 0,1145425 0,15121907 ! cell junction assembly GO:0034329 18 17 0,000 0,1145425 0,15111083 ! tissue remodeling GO:0048771 17 17 0,000 0,1145425 0,15100274 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,1145425 0,1508948 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,1145425 0,15078702 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,1145425 0,15067939 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,1145425 0,15057192 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,1145425 0,1504646 ! neural crest cell development GO:0014032 19 17 0,000 0,1145425 0,15035743 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,1145425 0,15025041 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,1145425 0,15014355 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,1145425 0,15003684 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,1145425 0,14993028 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,1145425 0,14982387 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,1145425 0,14971761 ! pigmentation GO:0043473 17 17 0,000 0,1145425 0,1496115 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,1145425 0,14950554 ! adult locomotory behavior GO:0008344 17 17 0,000 0,1145425 0,14939974 ! embryonic organ development GO:0048568 17 17 0,000 0,1145425 0,14929408 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,1145425 0,14918857 ! liver development GO:0001889 17 17 0,000 0,1145425 0,14908321 ! gene silencing GO:0016458 17 17 0,000 0,1145425 0,148978 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,11767375 0,15294268 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,12001668 0,15587791 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,12086443 0,15686841 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,12086443 0,15675802 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,12086443 0,15664778 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,12086443 0,1565377 ! meiosis I GO:0007127 18 18 0,000 0,12086443 0,15642777 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,12086443 0,156318 ! membrane docking GO:0022406 18 18 0,000 0,12086443 0,15620838 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,12086443 0,15609891 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,12086443 0,1559896 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,12086443 0,15588044 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,12086443 0,15577143 ! hexose transport GO:0008645 18 18 0,000 0,12086443 0,15566258 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 18 18 0,000 0,12086443 0,15555387 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,12086443 0,15544532 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,12086443 0,15533692 ! ceramide metabolic process GO:0006672 18 18 0,000 0,12086443 0,15522867 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,12086443 0,15512058 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,12086443 0,15501263 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,12086443 0,15490483 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,12086443 0,15479718 ! BMP signaling pathway GO:0030509 18 18 0,000 0,12086443 0,15468969 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,12086443 0,15458234 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,12086443 0,15447514 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,12086443 0,15436809 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,12473777 0,15920478 ! hexose metabolic process GO:0019318 87 86 1,000 0,12473777 0,15909461 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,12714214 0,16204908 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,12714214 0,16193709 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,12714214 0,16182525 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,12714214 0,16171357 ! feeding behavior GO:0007631 19 19 0,000 0,12714214 0,16160205 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,12714214 0,16149067 ! peroxisome organization GO:0007031 19 19 0,000 0,12714214 0,16137945 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,12714214 0,16126839 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,12714214 0,16115747 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,12714214 0,16104671 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,12714214 0,1609361 ! metanephros development GO:0001656 19 19 0,000 0,12714214 0,16082565 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,12714214 0,16071534 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,12714214 0,16060519 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,12714214 0,16049518 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,12714214 0,16038533 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,12714214 0,16027563 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,12714214 0,16016607 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,12714214 0,16005667 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,12714214 0,15994742 ! eye morphogenesis GO:0048592 19 19 0,000 0,12714214 0,15983831 ! regulation of cell shape GO:0008360 21 19 0,000 0,12714214 0,15972936 ! placenta development GO:0001890 19 19 0,000 0,12714214 0,15962055 ! response to heat GO:0009408 19 19 0,000 0,12714214 0,15951189 ! vesicle localization GO:0051648 20 19 0,000 0,12714214 0,15940338 ! chemotaxis GO:0006935 90 89 1,000 0,1319033 0,16526022 GO:0042330|taxis, ! regulation of muscle development GO:0048634 21 20 0,000 0,13337593 0,16699174 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,13337593 0,16687837 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,13337593 0,16676516 ! negative regulation of binding GO:0051100 21 20 0,000 0,13337593 0,1666521 ! organic ether metabolic process GO:0018904 20 20 0,000 0,13337593 0,16653919 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,13337593 0,16642643 ! phagocytosis GO:0006909 21 20 0,000 0,13337593 0,16631383 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,13337593 0,16620138 ! protein targeting to membrane GO:0006612 22 20 0,000 0,13337593 0,16608908 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,13337593 0,16597694 ! chromatin remodeling GO:0006338 20 20 0,000 0,13337593 0,16586494 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,13337593 0,1657531 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,13337593 0,1656414 ! lipid oxidation GO:0034440 20 20 0,000 0,13337593 0,16552986 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,13337593 0,16541847 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,13337593 0,16530722 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,13337593 0,16519613 ! RNA modification GO:0009451 20 20 0,000 0,13337593 0,16508519 ! single fertilization GO:0007338 21 20 0,000 0,13337593 0,16497439 ! brain development GO:0007420 91 90 1,000 0,13431311 0,16602217 ! DNA replication GO:0006260 91 91 1,000 0,13673312 0,16890023 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,13916309 0,17178672 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,1395661 0,1721689 ! mRNA catabolic process GO:0006402 21 21 0,000 0,1395661 0,17205373 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,1395661 0,17193872 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,1395661 0,17182387 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,1395661 0,17170916 ! Notch signaling pathway GO:0007219 22 21 0,000 0,1395661 0,17159462 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,1395661 0,17148022 ! ear morphogenesis GO:0042471 21 21 0,000 0,1395661 0,17136598 ! organic anion transport GO:0015711 21 21 0,000 0,1395661 0,17125188 ! spliceosome assembly GO:0000245 22 21 0,000 0,1395661 0,17113794 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,1395661 0,17102416 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,1395661 0,17091052 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,1395661 0,17079703 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,1395661 0,1706837 ! regulation of proteolysis GO:0030162 21 21 0,000 0,1395661 0,17057051 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,1395661 0,17045747 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,1395661 0,17034459 ! regulation of response to stress GO:0080134 97 94 1,000 0,14405184 0,17570321 ! blood vessel development GO:0001568 95 94 1,000 0,14405184 0,175587 ! pattern specification process GO:0007389 96 94 1,000 0,14405184 0,17547095 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,14571296 0,17737713 ! sister chromatid segregation GO:0000819 22 22 0,000 0,14571296 0,17726005 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,14571296 0,17714313 ! regulation of ion transport GO:0043269 22 22 0,000 0,14571296 0,17702635 ! odontogenesis GO:0042476 22 22 0,000 0,14571296 0,17690974 ! cell junction organization GO:0034330 23 22 0,000 0,14571296 0,17679327 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,14571296 0,17667696 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,14571296 0,1765608 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,14571296 0,1764448 ! ovulation cycle process GO:0022602 22 22 0,000 0,14571296 0,17632894 ! spindle organization GO:0007051 22 22 0,000 0,14571296 0,17621324 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,14571296 0,17609769 ! cell chemotaxis GO:0060326 23 22 0,000 0,14571296 0,17598229 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,14571296 0,17586705 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,14571296 0,17575195 ! male sex differentiation GO:0046661 22 22 0,000 0,14571296 0,175637 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,14571296 0,17552221 ! biopolymer methylation GO:0043414 22 22 0,000 0,14571296 0,17540756 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,14571296 0,17529307 ! detection of external stimulus GO:0009581 23 22 0,000 0,14571296 0,17517872 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,14571296 0,17506452 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,14571296 0,17495047 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,14571296 0,17483657 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,14571296 0,17472282 ! aerobic respiration GO:0009060 22 22 0,000 0,14571296 0,17460922 ! cytokine production GO:0001816 22 22 0,000 0,14571296 0,17449576 ! cytokinesis GO:0000910 23 22 0,000 0,14571296 0,17438245 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,14571296 0,17426929 ! vasculature development GO:0001944 97 96 1,000 0,14897736 0,17805789 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,15181679 0,18133398 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,15181679 0,18121654 ! viral infectious cycle GO:0019058 23 23 0,000 0,15181679 0,18109925 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,15181679 0,18098211 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,15181679 0,18086512 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,15181679 0,18074828 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,15181679 0,18063159 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,15181679 0,18051506 ! endocrine system development GO:0035270 23 23 0,000 0,15181679 0,18039867 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,15181679 0,18028243 ! female gonad development GO:0008585 23 23 0,000 0,15181679 0,18016635 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,15181679 0,18005041 ! regulation of system process GO:0044057 98 98 1,000 0,15393767 0,18244831 ! anti-apoptosis GO:0006916 100 99 1,000 0,15643027 0,18528341 ! gliogenesis GO:0042063 24 24 0,000 0,15787789 0,18687794 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,15787789 0,18675799 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,15787789 0,1866382 ! glucose homeostasis GO:0042593 24 24 0,000 0,15787789 0,18651856 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,15787789 0,18639907 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,15787789 0,18627974 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,15787789 0,18616056 ! ovulation cycle GO:0042698 24 24 0,000 0,15787789 0,18604153 ! fertilization GO:0009566 25 24 0,000 0,15787789 0,18592265 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,15787789 0,18580393 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,15787789 0,18568535 ! response to hormone stimulus GO:0009725 102 100 1,000 0,15893085 0,18680456 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,16389656 0,19251839 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,16389656 0,19239577 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,16389656 0,1922733 ! endosome transport GO:0016197 25 25 0,000 0,16389656 0,19215099 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,16389656 0,19202883 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,16389656 0,19190683 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,16389656 0,19178499 ! excretion GO:0007588 25 25 0,000 0,16389656 0,19166329 ! gastrulation GO:0007369 25 25 0,000 0,16389656 0,19154176 ! heart morphogenesis GO:0003007 25 25 0,000 0,16389656 0,19142038 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,16389656 0,19129915 ! regulation of endocytosis GO:0030100 25 25 0,000 0,16389656 0,19117807 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,16389656 0,19105715 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,16389656 0,19093638 ! positive regulation of defense response GO:0031349 26 26 0,000 0,16987308 0,1977739 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,16987308 0,19764904 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,16987308 0,19752434 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,16987308 0,1973998 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,16987308 0,19727542 ! cellular defense response GO:0006968 26 26 0,000 0,16987308 0,19715119 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,16987308 0,19702711 ! germ cell development GO:0007281 27 26 0,000 0,16987308 0,1969032 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,16987308 0,19677944 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,16987308 0,19665583 ! chloride transport GO:0006821 27 27 0,000 0,17580775 0,20339842 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,17580775 0,20327082 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,17580775 0,20314337 ! peptide metabolic process GO:0006518 29 27 0,000 0,17580775 0,20301609 ! inner ear development GO:0048839 27 27 0,000 0,17580775 0,20288897 ! defense response to bacterium GO:0042742 27 27 0,000 0,17580775 0,202762 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,17580775 0,2026352 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,17580775 0,20250855 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,18170085 0,20916594 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,18170085 0,20903537 ! carbohydrate transport GO:0008643 28 28 0,000 0,18170085 0,20890497 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,18170085 0,20877473 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,18170085 0,20864465 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,18170085 0,20851473 ! developmental growth GO:0048589 28 28 0,000 0,18170085 0,20838498 ! cartilage development GO:0051216 29 28 0,000 0,18170085 0,20825539 ! viral reproductive process GO:0022415 29 29 0,000 0,18755267 0,21482882 ! leukocyte migration GO:0050900 30 29 0,000 0,18755267 0,21469538 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,18755267 0,21456211 ! antigen processing and presentation GO:0019882 29 29 0,000 0,18755267 0,21442901 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,18755267 0,21429607 ! tRNA processing GO:0008033 29 29 0,000 0,18755267 0,2141633 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,18755267 0,21403069 ! adult behavior GO:0030534 30 29 0,000 0,18755267 0,21389825 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,18755267 0,21376596 ! transition metal ion transport GO:0000041 31 30 0,000 0,19336349 0,22025272 ! RNA catabolic process GO:0006401 30 30 0,000 0,19336349 0,22011668 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,19336349 0,2199808 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,19336349 0,2198451 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,19336349 0,21970956 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,19336349 0,21957419 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,19336349 0,21943898 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,19336349 0,21930394 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,19336349 0,21916907 ! response to temperature stimulus GO:0009266 30 30 0,000 0,19336349 0,21903436 ! regulation of ossification GO:0030278 30 30 0,000 0,19336349 0,21889982 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,19336349 0,21876544 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,19336349 0,21863123 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,19336349 0,21849718 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,19336349 0,2183633 ! vesicle organization GO:0016050 30 30 0,000 0,19336349 0,21822958 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,19336349 0,21809602 ! establishment of organelle localization GO:0051656 31 30 0,000 0,19336349 0,21796263 ! regulation of translational initiation GO:0006446 31 31 0,000 0,19913359 0,22432958 ! membrane fusion GO:0006944 31 31 0,000 0,19913359 0,22419255 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,19913359 0,22405568 ! ion transmembrane transport GO:0034220 31 31 0,000 0,19913359 0,22391897 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! digestion GO:0007586 31 31 0,000 0,19913359 0,22378244 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,19913359 0,22364607 ! regulation of heart contraction GO:0008016 31 31 0,000 0,19913359 0,22350987 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,19913359 0,22337383 ! camera-type eye development GO:0043010 31 31 0,000 0,19913359 0,22323796 ! extracellular matrix organization GO:0030198 31 31 0,000 0,19913359 0,22310225 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,19913359 0,22296671 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,19913359 0,22283133 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,19913359 0,22269612 ! cell redox homeostasis GO:0045454 32 32 0,000 0,20486325 0,22896481 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,20486325 0,22882604 ! cell maturation GO:0048469 32 32 0,000 0,20486325 0,22868744 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,20486325 0,22854901 ! kidney development GO:0001822 32 32 0,000 0,20486325 0,22841075 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,20486325 0,22827265 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,21055275 0,23447052 ! amino acid transport GO:0006865 33 33 0,000 0,21055275 0,23432893 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,21055275 0,23418752 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,21055275 0,23404627 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,21055275 0,23390519 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,21055275 0,23376429 ! regulation of actin filament length GO:0030832 34 34 0,000 0,21620236 0,23989221 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,21620236 0,23974787 ! response to metal ion GO:0010038 34 34 0,000 0,21620236 0,2396037 ! ear development GO:0043583 34 34 0,000 0,21620236 0,23945971 ! muscle cell differentiation GO:0042692 35 34 0,000 0,21620236 0,23931589 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,21620236 0,23917224 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,21620236 0,23902877 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,21620236 0,23888547 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,21620236 0,23874233 ! secondary metabolic process GO:0019748 34 34 0,000 0,21620236 0,23859938 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,21620236 0,23845659 ! viral reproduction GO:0016032 34 34 0,000 0,21620236 0,23831397 ! detection of stimulus GO:0051606 36 34 0,000 0,21620236 0,23817152 ! acute inflammatory response GO:0002526 35 35 0,000 0,22181237 0,24420561 ! regulation of cellular component size GO:0032535 35 35 0,000 0,22181237 0,24405982 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,22181237 0,2439142 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,22181237 0,24376875 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,22181237 0,24362348 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,22181237 0,24347838 ! inorganic anion transport GO:0015698 35 35 0,000 0,22181237 0,24333345 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,22181237 0,24318869 ! hydrogen transport GO:0006818 36 36 0,000 0,22738303 0,24914799 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,22738303 0,24899996 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,22738303 0,24885209 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,22738303 0,24870441 ! regulation of mitosis GO:0007088 37 36 0,000 0,22738303 0,2485569 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,22738303 0,24840956 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,22738303 0,2482624 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,22738303 0,24811541 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,22738303 0,2479686 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,22738303 0,24782196 ! gonad development GO:0008406 36 36 0,000 0,22738303 0,24767549 ! activation of immune response GO:0002253 36 36 0,000 0,22738303 0,24752919 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,23291463 0,25340121 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,23291463 0,25325171 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,23291463 0,25310239 ! eye development GO:0001654 37 37 0,000 0,23291463 0,25295324 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,23291463 0,25280427 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,23291463 0,25265548 ! adaptive immune response GO:0002250 37 37 0,000 0,23291463 0,25250686 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,23840742 0,25830974 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,23840742 0,25815797 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,23840742 0,25800638 ! chromosome segregation GO:0007059 38 38 0,000 0,23840742 0,25785497 ! RNA elongation GO:0006354 38 38 0,000 0,23840742 0,25770374 ! meiotic cell cycle GO:0051321 38 38 0,000 0,23840742 0,25755268 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,23840742 0,2574018 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,24386168 0,26313646 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,24386168 0,26298249 ! activation of MAPK activity GO:0000187 39 39 0,000 0,24386168 0,2628287 ! response to unfolded protein GO:0006986 39 39 0,000 0,24386168 0,26267509 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,24386168 0,26252165 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,24386168 0,2623684 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,24386168 0,26221533 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,24386168 0,26206243 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,24386168 0,26190972 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,24386168 0,26175718 ! developmental maturation GO:0021700 39 39 0,000 0,24386168 0,26160481 ! limb development GO:0060173 39 39 0,000 0,24386168 0,26145263 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,24927767 0,26710392 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,24927767 0,26694871 ! organelle localization GO:0051640 41 40 0,000 0,24927767 0,26679369 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,25465565 0,27239139 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,25465565 0,27223339 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,25465565 0,27207557 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,25465565 0,27191794 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,25999588 0,27745942 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,25999588 0,27729885 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,25999588 0,27713847 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,25999588 0,27697827 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,25999588 0,27681826 ! response to protein stimulus GO:0051789 42 42 0,000 0,25999588 0,27665844 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,25999588 0,2764988 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,26529863 0,28197542 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,26529863 0,2818129 ! humoral immune response GO:0006959 44 44 0,000 0,27056415 0,28724063 ! mRNA transport GO:0051028 44 44 0,000 0,27056415 0,28707527 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,27056415 0,28691009 ! vitamin metabolic process GO:0006766 44 44 0,000 0,27056415 0,2867451 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,27056415 0,28658031 ! amine biosynthetic process GO:0009309 46 45 0,000 0,2757927 0,29195057 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,2757927 0,29178298 ! protein processing GO:0016485 45 45 0,000 0,2757927 0,29161558 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,28098453 0,29693492 ! tube morphogenesis GO:0035239 47 46 0,000 0,28098453 0,29676475 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,28098453 0,29659478 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,28098453 0,29642501 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,2861399 0,30169098 ! regulation of blood pressure GO:0008217 48 47 0,000 0,2861399 0,30151848 ! amine transport GO:0015837 47 47 0,000 0,2861399 0,30134619 ! rhythmic process GO:0048511 47 47 0,000 0,2861399 0,30117409 ! regulation of catabolic process GO:0009894 48 47 0,000 0,2861399 0,30100219 ! calcium ion transport GO:0006816 48 48 0,000 0,29125905 0,30621245 ! actin filament organization GO:0007015 50 48 0,000 0,29125905 0,30603787 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,29125905 0,30586349 ! DNA recombination GO:0006310 48 48 0,000 0,29125905 0,30568931 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,29634223 0,31084731 ! divalent metal ion transport GO:0070838 49 49 0,000 0,29634223 0,31067049 ! response to nutrient GO:0007584 49 49 0,000 0,29634223 0,31049388 ! response to bacterium GO:0009617 50 49 0,000 0,29634223 0,31031746 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,29634223 0,31014124 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,29634223 0,30996523 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,30138969 0,31506591 ! chromatin assembly GO:0031497 50 50 0,000 0,30138969 0,3148873 GO:0006334|nucleosome assembly, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,30138969 0,3147089 ! transcription initiation GO:0006352 50 50 0,000 0,30138969 0,31453069 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,30138969 0,31435269 ! positive regulation of immune response GO:0050778 51 51 0,000 0,30640168 0,31939949 ! rRNA metabolic process GO:0016072 51 51 0,000 0,30640168 0,31921894 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,30640168 0,31903859 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,30640168 0,31885844 ! protein maturation GO:0051604 51 51 0,000 0,30640168 0,3186785 ! sodium ion transport GO:0006814 53 53 0,000 0,31632023 0,3288089 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,31632023 0,32862355 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,32122726 0,33353343 ! response to virus GO:0009615 54 54 0,000 0,32122726 0,33334563 ! hormone metabolic process GO:0042445 55 54 0,000 0,32122726 0,33315804 ! sulfur metabolic process GO:0006790 55 54 0,000 0,32122726 0,33297066 ! nucleosome organization GO:0034728 55 55 0,000 0,32609978 0,33783131 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,32609978 0,33764152 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,33093804 0,34245863 ! ATP metabolic process GO:0046034 57 57 0,000 0,33574227 0,34723513 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,33574227 0,34704038 ! innate immune response GO:0045087 58 58 0,000 0,3405127 0,35177405 ! dephosphorylation GO:0016311 60 59 0,000 0,34524956 0,35646775 ! carboxylic acid transport GO:0046942 59 59 0,000 0,34524956 0,35626816 GO:0015849|organic acid transport, ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,34524956 0,35606879 ! immune effector process GO:0002252 59 59 0,000 0,34524956 0,35586965 ! potassium ion transport GO:0006813 60 60 0,000 0,34995309 0,36051623 ! protein polymerization GO:0051258 65 60 0,000 0,34995309 0,36031483 ! cellular respiration GO:0045333 62 61 0,000 0,35462351 0,36491967 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,35462351 0,36471603 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,35462351 0,36451262 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,35926106 0,36907365 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,35926106 0,36886804 GO:0060429|epithelium development, ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,35926106 0,36866266 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,36386596 0,37318028 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,36386596 0,37297273 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,36386596 0,37276541 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,36843844 0,37724002 ! anion transport GO:0006820 65 65 0,000 0,37297871 0,38167672 ! regulation of hormone levels GO:0010817 66 65 0,000 0,37297871 0,38146491 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,37748701 0,38586165 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,37748701 0,38564776 ! DNA packaging GO:0006323 66 66 0,000 0,37748701 0,3854341 ! muscle contraction GO:0006936 67 67 0,000 0,38196355 0,38978894 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,38640855 0,39410678 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,38640855 0,3938888 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,3952048 0,40263264 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,39955649 0,40684122 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,39955649 0,40661657 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,39955649 0,40639216 GO:0006874|cellular calcium ion homeostasis, ! muscle system process GO:0003012 72 72 0,000 0,40387749 0,41056052 ! sensory organ development GO:0007423 72 72 0,000 0,40387749 0,41033419 ! electron transport chain GO:0022900 75 74 0,000 0,41242832 0,41879085 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,41242832 0,41856024 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,41665856 0,42262065 ! response to oxidative stress GO:0006979 76 75 0,000 0,41665856 0,42238819 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,41665856 0,42215598 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,42085896 0,42617751 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,42502973 0,43016463 ! metal ion homeostasis GO:0055065 78 78 0,000 0,42917107 0,43411761 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,43736628 0,44216459 ! MAPKKK cascade GO:0000165 82 81 0,000 0,44142055 0,44601868 ! lipid catabolic process GO:0016042 82 81 0,000 0,44142055 0,44577429 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,44944343 0,45362773 ! ncRNA processing GO:0034470 83 83 0,000 0,44944343 0,45337944 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,45735339 0,46110629 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,45735339 0,46085418 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,45735339 0,46060235 ! male gamete generation GO:0048232 90 88 0,000 0,46901002 0,47208381 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,46901002 0,47182612 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,47284077 0,47542037 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,48042125 0,48277882 ! visual perception GO:0007601 93 92 0,000 0,48417134 0,48628217 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,48417134 0,48601731 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,48417134 0,48575274 ! tissue morphogenesis GO:0048729 94 93 0,000 0,48789491 0,48922215 ! cofactor metabolic process GO:0051186 95 94 0,000 0,49159215 0,49266141 ! endocytosis GO:0006897 99 98 0,000 0,50612138 0,50694658 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,50612138 0,50667121 ! blood circulation GO:0008015 99 98 0,000 0,50612138 0,50639615 GO:0003013|circulatory system process, ! response to other organism GO:0051707 101 100 0,000 0,51323268 0,51323268