pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6542-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! apoptotic mitochondrial changes GO:0008637 29 18 5,000 1,303E-09 2,997E-06 ! release of cytochrome c from mitochondria GO:0001836 23 14 4,000 2,251E-08 2,589E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 3,000 1,262E-07 9,676E-05 ! induction of apoptosis by intracellular signals GO:0008629 67 40 5,000 2,393E-07 1,376E-04 ! regulation of B cell proliferation GO:0030888 15 10 3,000 3,748E-07 1,724E-04 ! negative regulation of mast cell proliferation GO:0070667 17 11 3,000 5,859E-07 2,246E-04 GO:0042130|negative regulation of T cell proliferation, ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 1,058E-06 3,476E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 5,000 2,064E-06 5,933E-04 ! negative regulation of kinase activity GO:0033673 100 58 5,000 2,289E-06 5,851E-04 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 3,000 2,374E-06 5,461E-04 ! negative regulation of leukocyte proliferation GO:0070664 25 15 3,000 2,374E-06 4,964E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of transferase activity GO:0051348 105 61 5,000 3,09E-06 5,923E-04 ! regulation of caspase activity GO:0043281 97 65 5,000 4,499E-06 7,96E-04 ! negative regulation of T cell activation GO:0050868 25 18 3,000 5,241E-06 8,611E-04 ! regulation of endopeptidase activity GO:0052548 99 67 5,000 5,378E-06 8,246E-04 ! ER overload response GO:0006983 7 6 2,000 5,611E-06 8,066E-04 ! negative regulation of B cell activation GO:0050869 9 6 2,000 5,611E-06 7,592E-04 ! cell structure disassembly during apoptosis GO:0006921 24 19 3,000 6,605E-06 8,44E-04 ! apoptotic nuclear changes GO:0030262 24 19 3,000 6,605E-06 7,995E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 5,000 7,553E-06 8,686E-04 ! regulation of peptidase activity GO:0052547 106 72 5,000 8,195E-06 8,976E-04 ! cellular component disassembly GO:0022411 64 42 4,000 8,247E-06 8,622E-04 ! mitochondrion organization GO:0007005 104 73 5,000 8,881E-06 8,881E-04 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 3,000 1,009E-05 9,674E-04 ! regulation of ligase activity GO:0051340 114 75 5,000 1,039E-05 9,561E-04 ! regulation of mast cell proliferation GO:0070666 64 44 4,000 1,042E-05 9,216E-04 ! response to UV GO:0009411 75 46 4,000 1,301E-05 1,108E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 4,000 1,448E-05 1,19E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 2,000 1,556E-05 1,234E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 1,556E-05 1,193E-03 ! negative regulation of lymphocyte activation GO:0051250 37 25 3,000 2,09E-05 1,551E-03 ! cell cycle arrest GO:0007050 150 86 5,000 2,287E-05 1,644E-03 ! negative regulation of leukocyte activation GO:0002695 39 27 3,000 2,871E-05 2,001E-03 ! regulation of B cell activation GO:0050864 42 28 3,000 3,332E-05 2,254E-03 ! negative regulation of cell activation GO:0050866 44 30 3,000 4,414E-05 2,901E-03 ! negative regulation of ligase activity GO:0051352 91 61 4,000 5,217E-05 3,333E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 4,000 5,217E-05 3,243E-03 ! negative regulation of cell growth GO:0030308 106 62 4,000 5,645E-05 3,417E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 4,000 5,645E-05 3,329E-03 ! nucleus organization GO:0006997 49 33 3,000 6,491E-05 3,732E-03 ! negative regulation of cell size GO:0045792 108 64 4,000 6,581E-05 3,692E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 4,000 7,092E-05 3,884E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 4,000 7,092E-05 3,793E-03 ! keratinocyte differentiation GO:0030216 47 35 3,000 8,221E-05 4,297E-03 ! positive regulation of ligase activity GO:0051351 99 69 4,000 9,448E-05 4,829E-03 ! regulation of T cell proliferation GO:0042129 58 38 3,000 1,141E-04 5,706E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 1,222E-04 5,98E-03 ! epidermal cell differentiation GO:0009913 53 40 3,000 1,399E-04 6,702E-03 ! blood coagulation GO:0007596 116 75 4,000 1,406E-04 6,599E-03 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 4,000 1,406E-04 6,467E-03 ! phosphatidylinositol metabolic process GO:0046488 22 17 2,000 1,809E-04 8,157E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 1,809E-04 8E-03 ! peptidyl-serine modification GO:0018209 27 17 2,000 1,809E-04 7,849E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 1,86E-04 7,922E-03 ! activation of caspase activity GO:0006919 65 43 3,000 1,86E-04 7,778E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 4,000 1,907E-04 7,834E-03 GO:0010498|proteasomal protein catabolic process, ! hemostasis GO:0007599 125 81 4,000 2,022E-04 8,16E-03 ! regulation of DNA metabolic process GO:0051052 135 85 4,000 2,535E-04 0,01005216 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 2,553E-04 9,951E-03 ! calcium-independent cell-cell adhesion GO:0016338 21 19 2,000 2,553E-04 9,785E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 2,553E-04 9,625E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 2,000 2,553E-04 9,469E-03 ! negative regulation of immune system process GO:0002683 73 47 3,000 2,634E-04 9,616E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 2,677E-04 9,621E-03 ! positive regulation of caspase activity GO:0043280 72 48 3,000 2,859E-04 0,01011546 GO:0010952|positive regulation of peptidase activity, ! regulation of DNA replication GO:0006275 75 48 3,000 2,859E-04 9,962E-03 ! interphase GO:0051325 159 88 4,000 2,98E-04 0,01023021 ! microtubule-based transport GO:0010970 37 20 2,000 2,989E-04 0,01010838 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 3,47E-04 0,01156612 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 3,47E-04 0,01140089 ! platelet activation GO:0030168 28 21 2,000 3,47E-04 0,01124031 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 3,47E-04 0,0110842 ! glycerophospholipid metabolic process GO:0006650 130 92 4,000 3,663E-04 0,01154119 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 3,998E-04 0,01242722 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 3,998E-04 0,01226152 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 4,308E-04 0,01303883 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 4,308E-04 0,01286949 ! lipoprotein particle clearance GO:0034381 9 5 1,000 4,308E-04 0,0127045 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 4,308E-04 0,01254368 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 4,308E-04 0,01238688 ! induction of apoptosis by oxidative stress GO:0008631 5 5 1,000 4,308E-04 0,01223396 ! microvillus organization GO:0032528 7 5 1,000 4,308E-04 0,01208477 GO:0030033|microvillus assembly, ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 4,308E-04 0,01193917 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 4,308E-04 0,01179703 ! triglyceride catabolic process GO:0019433 6 5 1,000 4,308E-04 0,01165824 ! response to light stimulus GO:0009416 153 96 4,000 4,458E-04 0,01192331 ! DNA catabolic process GO:0006308 67 54 3,000 4,506E-04 0,01191322 ! positive regulation of cell adhesion GO:0045785 37 23 2,000 4,576E-04 0,01195973 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 4,576E-04 0,01182535 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 4,576E-04 0,01169396 ! negative regulation of DNA replication GO:0008156 35 23 2,000 4,576E-04 0,01156545 ! negative regulation of phosphorylation GO:0042326 41 23 2,000 4,576E-04 0,01143974 ! DNA damage response, signal transduction GO:0042770 96 56 3,000 5,181E-04 0,01281203 ! regulation of body fluid levels GO:0050878 154 100 4,000 5,377E-04 0,01315696 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 5,886E-04 0,01424927 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of helicase activity GO:0051095 11 6 1,000 6,435E-04 0,01541639 ! prostate gland development GO:0030850 9 6 1,000 6,435E-04 0,01525746 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 6,435E-04 0,01510177 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 6,435E-04 0,01494922 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 1,000 6,435E-04 0,01479973 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 6,435E-04 0,0146532 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 6,435E-04 0,01450954 ! glycerol ether catabolic process GO:0044269 8 6 1,000 6,435E-04 0,01436867 GO:0046464|acylglycerol catabolic process, ! neuron apoptosis GO:0051402 8 6 1,000 6,435E-04 0,01423051 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 1,000 6,435E-04 0,01409498 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 6,435E-04 0,01396201 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 2,000 6,621E-04 0,01423247 ! phosphoinositide metabolic process GO:0030384 87 60 3,000 6,739E-04 0,01435219 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 3,000 6,739E-04 0,01422051 ! cholesterol homeostasis GO:0042632 46 28 2,000 8,263E-04 0,0172762 GO:0055092|sterol homeostasis, ! cell cycle checkpoint GO:0000075 108 64 3,000 8,604E-04 0,01782857 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 8,969E-04 0,01841939 ! neutral lipid catabolic process GO:0046461 9 7 1,000 8,969E-04 0,01825639 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 8,969E-04 0,01809625 ! lipoprotein transport GO:0042953 9 7 1,000 8,969E-04 0,01793889 ! microtubule bundle formation GO:0001578 8 7 1,000 8,969E-04 0,01778424 ! glycerolipid catabolic process GO:0046503 9 7 1,000 8,969E-04 0,01763224 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 8,969E-04 0,01748281 ! fibrinolysis GO:0042730 9 7 1,000 8,969E-04 0,0173359 ! B cell lineage commitment GO:0002326 17 7 1,000 8,969E-04 0,01719143 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 8,969E-04 0,01704936 ! T cell lineage commitment GO:0002360 12 7 1,000 8,969E-04 0,01690961 ! response to tumor cell GO:0002347 12 7 1,000 8,969E-04 0,01677213 ! peptidyl-threonine modification GO:0018210 18 7 1,000 8,969E-04 0,01663687 ! cholesterol transport GO:0030301 46 30 2,000 1,014E-03 0,01866045 GO:0015918|sterol transport, ! regulation of microtubule-based process GO:0032886 58 30 2,000 1,014E-03 0,01851235 ! DNA damage checkpoint GO:0000077 53 31 2,000 1,117E-03 0,02023659 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,191E-03 0,0213961 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,191E-03 0,02123024 ! keratinocyte proliferation GO:0043616 12 8 1,000 1,191E-03 0,02106693 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,191E-03 0,02090611 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,191E-03 0,02074773 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 1,191E-03 0,02059173 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 1,000 1,191E-03 0,02043806 ! negative regulation of cytokine secretion GO:0050710 12 8 1,000 1,191E-03 0,02028667 ! regulation of interleukin-1 beta secretion GO:0050706 11 8 1,000 1,191E-03 0,0201375 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,191E-03 0,01999051 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 1,191E-03 0,01984565 GO:0000076|DNA replication checkpoint, ! negative regulation of DNA metabolic process GO:0051053 48 32 2,000 1,227E-03 0,02030412 ! regulation of protein stability GO:0031647 48 32 2,000 1,227E-03 0,02015909 ! response to hypoxia GO:0001666 132 72 3,000 1,338E-03 0,02182025 ! lipid homeostasis GO:0055088 55 33 2,000 1,343E-03 0,02175755 ! negative regulation of hydrolase activity GO:0051346 50 33 2,000 1,343E-03 0,0216054 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 1,343E-03 0,02145536 ! DNA integrity checkpoint GO:0031570 57 34 2,000 1,466E-03 0,02325706 ! response to oxygen levels GO:0070482 137 74 3,000 1,481E-03 0,02333046 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 1,524E-03 0,02384982 ! regulation of activated T cell proliferation GO:0046006 15 9 1,000 1,524E-03 0,02368867 ! artery development GO:0060840 19 9 1,000 1,524E-03 0,02352968 GO:0048844|artery morphogenesis, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 1,524E-03 0,02337282 ! regulation of stress fiber formation GO:0051492 20 9 1,000 1,524E-03 0,02321803 ! motor axon guidance GO:0008045 14 9 1,000 1,524E-03 0,02306528 ! regulation of DNA replication initiation GO:0030174 13 9 1,000 1,524E-03 0,02291453 ! regulation of interleukin-1 secretion GO:0050704 12 9 1,000 1,524E-03 0,02276573 ! oocyte differentiation GO:0009994 12 9 1,000 1,524E-03 0,02261886 GO:0048599|oocyte development, ! localization within membrane GO:0051668 15 9 1,000 1,524E-03 0,02247387 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 1,596E-03 0,02338025 ! regulation of protein transport GO:0051223 114 76 3,000 1,635E-03 0,0237955 GO:0070201|regulation of establishment of protein localization, ! regulation of phosphatase activity GO:0010921 21 10 1,000 1,897E-03 0,02744288 ! phospholipid efflux GO:0033700 16 10 1,000 1,897E-03 0,02727136 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,897E-03 0,02710197 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 1,897E-03 0,02693467 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,897E-03 0,02676943 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 1,897E-03 0,0266062 ! reverse cholesterol transport GO:0043691 16 10 1,000 1,897E-03 0,02644495 ! response to X-ray GO:0010165 16 10 1,000 1,897E-03 0,02628565 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 1,897E-03 0,02612825 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 1,897E-03 0,02597272 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 2,186E-03 0,02975012 ! regulation of cell adhesion GO:0030155 159 83 3,000 2,26E-03 0,03057206 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,309E-03 0,03105247 ! detection of mechanical stimulus GO:0050982 15 11 1,000 2,309E-03 0,03087193 ! regulated secretory pathway GO:0045055 14 11 1,000 2,309E-03 0,03069348 ! regulation of intracellular pH GO:0051453 17 11 1,000 2,309E-03 0,03051708 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 2,309E-03 0,0303427 ! T cell homeostasis GO:0043029 20 11 1,000 2,309E-03 0,03017029 ! cholesterol efflux GO:0033344 19 11 1,000 2,309E-03 0,02999984 ! regulation of steroid biosynthetic process GO:0050810 11 11 1,000 2,309E-03 0,0298313 ! response to calcium ion GO:0051592 58 40 2,000 2,352E-03 0,0302198 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 2,000 2,352E-03 0,03005191 ! T cell differentiation GO:0030217 65 40 2,000 2,352E-03 0,02988588 ! positive regulation of protein transport GO:0051222 55 40 2,000 2,352E-03 0,02972167 ! regulation of protein localization GO:0032880 132 85 3,000 2,465E-03 0,0309774 ! regulation of T cell differentiation GO:0045580 59 41 2,000 2,525E-03 0,03156738 ! Wnt receptor signaling pathway GO:0016055 130 87 3,000 2,682E-03 0,03334657 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 2,707E-03 0,03346882 ! positive regulation of cell growth GO:0030307 16 12 1,000 2,758E-03 0,03392721 ! phosphatidylcholine biosynthetic process GO:0006656 17 12 1,000 2,758E-03 0,03374674 ! histone acetylation GO:0016573 23 12 1,000 2,758E-03 0,03356819 ! peptidyl-lysine modification GO:0018205 18 12 1,000 2,758E-03 0,03339152 ! negative regulation of protein secretion GO:0050709 20 12 1,000 2,758E-03 0,03321669 ! response to gamma radiation GO:0010332 20 12 1,000 2,758E-03 0,03304369 ! regulation of T cell activation GO:0050863 128 89 3,000 2,913E-03 0,03470905 ! glycolysis GO:0006096 53 44 2,000 3,093E-03 0,03666529 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 3,246E-03 0,0382845 ! induction of apoptosis via death domain receptors GO:0008625 15 13 1,000 3,246E-03 0,03808918 ! intermediate filament cytoskeleton organization GO:0045104 23 13 1,000 3,246E-03 0,03789583 ! regulation of cytokine production during immune response GO:0002718 18 13 1,000 3,246E-03 0,03770444 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 3,246E-03 0,03751497 ! regulation of cellular pH GO:0030641 20 13 1,000 3,246E-03 0,03732739 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 3,246E-03 0,03714168 ! tissue regeneration GO:0042246 21 13 1,000 3,246E-03 0,03695781 ! lymphocyte homeostasis GO:0002260 24 13 1,000 3,246E-03 0,03677576 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 3,298E-03 0,03717954 ! regulation of cytoskeleton organization GO:0051493 154 93 3,000 3,413E-03 0,03829315 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 3,413E-03 0,03810726 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 3,77E-03 0,04189404 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 3,77E-03 0,04169263 ! cellular response to starvation GO:0009267 21 14 1,000 3,77E-03 0,04149314 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 3,77E-03 0,04129556 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of caspase activity GO:0043154 20 14 1,000 3,77E-03 0,04109984 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 3,77E-03 0,04090598 ! G1/S transition checkpoint GO:0031575 33 14 1,000 3,77E-03 0,04071393 ! intermediate filament-based process GO:0045103 24 14 1,000 3,77E-03 0,04052368 ! axon cargo transport GO:0008088 27 14 1,000 3,77E-03 0,0403352 ! negative regulation of blood coagulation GO:0030195 19 14 1,000 3,77E-03 0,04014846 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 3,77E-03 0,03996344 ! in utero embryonic development GO:0001701 147 96 3,000 3,825E-03 0,04035356 ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 3,962E-03 0,04161015 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 3,000 3,969E-03 0,04149631 ! regulation of intracellular transport GO:0032386 78 49 2,000 4,2E-03 0,04371253 ! germ cell development GO:0007281 68 49 2,000 4,2E-03 0,04351563 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 4,332E-03 0,04467709 ! positive regulation of cell size GO:0045793 20 15 1,000 4,332E-03 0,04447763 ! skin development GO:0043588 25 15 1,000 4,332E-03 0,04427996 ! regulation of survival gene product expression GO:0045884 20 15 1,000 4,332E-03 0,04408403 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 4,332E-03 0,04388982 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 4,332E-03 0,04369733 ! protein amino acid acetylation GO:0006473 28 16 1,000 4,929E-03 0,04950697 ! fructose metabolic process GO:0006000 20 16 1,000 4,929E-03 0,04929172 ! regulation of dephosphorylation GO:0035303 33 16 1,000 4,929E-03 0,04907833 ! regulation of steroid metabolic process GO:0019218 21 16 1,000 4,929E-03 0,04886679 ! oogenesis GO:0048477 23 16 1,000 4,929E-03 0,04865706 ! G1 phase GO:0051318 27 16 1,000 4,929E-03 0,04844912 ! negative regulation of translation GO:0017148 22 16 1,000 4,929E-03 0,04824296 ! aging GO:0007568 79 52 2,000 4,966E-03 0,04840031 ! glucose catabolic process GO:0006007 66 54 2,000 5,521E-03 0,05357721 ! phosphatidylcholine metabolic process GO:0046470 22 17 1,000 5,562E-03 0,05375311 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 5,562E-03 0,0535282 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 5,562E-03 0,05330517 ! neuromuscular junction development GO:0007528 23 17 1,000 5,562E-03 0,05308398 ! negative regulation of coagulation GO:0050819 23 17 1,000 5,562E-03 0,05286463 ! exocytosis GO:0006887 74 55 2,000 5,811E-03 0,05500497 ! protein amino acid ADP-ribosylation GO:0006471 27 18 1,000 6,231E-03 0,05873072 ! peptide cross-linking GO:0018149 31 18 1,000 6,231E-03 0,058491 ! somitogenesis GO:0001756 24 18 1,000 6,231E-03 0,05825323 ! cellular response to nutrient levels GO:0031669 27 18 1,000 6,231E-03 0,05801739 ! regulation of cytokine secretion GO:0050707 26 18 1,000 6,231E-03 0,05778345 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 6,231E-03 0,05755139 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 6,738E-03 0,06198573 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 6,934E-03 0,06353443 ! regeneration GO:0031099 32 19 1,000 6,934E-03 0,06328231 ! response to alkaloid GO:0043279 32 19 1,000 6,934E-03 0,06303218 ! response to starvation GO:0042594 30 19 1,000 6,934E-03 0,06278402 ! sex determination GO:0007530 29 19 1,000 6,934E-03 0,06253781 ! protein stabilization GO:0050821 26 19 1,000 6,934E-03 0,06229352 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 7,671E-03 0,06864853 ! positive regulation of B cell activation GO:0050871 31 20 1,000 7,671E-03 0,06838245 ! lipoprotein metabolic process GO:0042157 89 61 2,000 7,747E-03 0,06879311 ! urogenital system development GO:0001655 101 61 2,000 7,747E-03 0,06852852 ! protein amino acid acylation GO:0043543 37 21 1,000 8,442E-03 0,07439 ! dendrite development GO:0016358 35 21 1,000 8,442E-03 0,07410607 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 8,442E-03 0,07382429 ! cell aging GO:0007569 32 21 1,000 8,442E-03 0,07354466 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 8,442E-03 0,07326713 ! regulation of transcription factor activity GO:0051090 97 63 2,000 8,466E-03 0,07320528 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 8,466E-03 0,07293111 ! hexose catabolic process GO:0019320 82 64 2,000 8,84E-03 0,07586921 ! reproductive structure development GO:0048608 90 65 2,000 9,224E-03 0,07886722 ! protein oligomerization GO:0051259 100 65 2,000 9,224E-03 0,07857512 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 9,246E-03 0,07847014 ! macromolecular complex disassembly GO:0032984 38 22 1,000 9,246E-03 0,07818164 ! vasculogenesis GO:0001570 33 22 1,000 9,246E-03 0,07789526 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 9,246E-03 0,07761097 ! leukocyte homeostasis GO:0001776 33 22 1,000 9,246E-03 0,07732875 ! regulation of blood coagulation GO:0030193 34 22 1,000 9,246E-03 0,07704858 ! protein tetramerization GO:0051262 39 22 1,000 9,246E-03 0,07677042 ! regulation of Rho protein signal transduction GO:0035023 111 66 2,000 9,617E-03 0,07956734 ! myelination GO:0042552 35 23 1,000 0,0100828 0,08311989 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,0100828 0,08282303 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 0,0100828 0,08252829 ! ethanolamine and derivative metabolic process GO:0042439 33 23 1,000 0,0100828 0,08223564 ! sperm motility GO:0030317 27 24 1,000 0,01095211 0,08901008 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01095211 0,08869667 ! response to toxin GO:0009636 38 24 1,000 0,01095211 0,08838545 ! negative regulation of cell development GO:0010721 56 24 1,000 0,01095211 0,08807641 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 0,01095211 0,08776952 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,01095211 0,08746477 ! neurotransmitter secretion GO:0007269 32 24 1,000 0,01095211 0,08716212 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 0,01095211 0,08686156 ! response to metal ion GO:0010038 103 70 2,000 0,01128722 0,08921167 ! lymphocyte differentiation GO:0030098 113 71 2,000 0,01172916 0,09238722 ! monosaccharide catabolic process GO:0046365 91 71 2,000 0,01172916 0,09207191 ! male gonad development GO:0008584 33 25 1,000 0,01185329 0,09272981 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01185329 0,09241547 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,01185329 0,09210326 ! phospholipid transport GO:0015914 35 25 1,000 0,01185329 0,09179315 ! regulation of pH GO:0006885 36 26 1,000 0,01278589 0,09868301 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,01278589 0,09835297 ! post-embryonic development GO:0009791 42 26 1,000 0,01278589 0,09802513 ! negative regulation of protein modification process GO:0031400 50 26 1,000 0,01278589 0,09769946 ! regulation of coagulation GO:0050818 39 26 1,000 0,01278589 0,09737595 ! response to inorganic substance GO:0010035 115 75 2,000 0,01359586 0,10320286 ! response to ionizing radiation GO:0010212 47 27 1,000 0,01374945 0,10402547 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 0,01374945 0,1036844 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,01374945 0,10334557 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 1,000 0,01374945 0,10300893 ! cholesterol metabolic process GO:0008203 109 77 2,000 0,01458898 0,10894365 ! regulation of DNA binding GO:0051101 119 77 2,000 0,01458898 0,10859108 ! gland development GO:0048732 148 77 2,000 0,01458898 0,10824079 ! sex differentiation GO:0007548 105 77 2,000 0,01458898 0,10789275 ! GPI anchor metabolic process GO:0006505 40 28 1,000 0,01474355 0,1086864 ! triglyceride metabolic process GO:0006641 34 28 1,000 0,01474355 0,10833915 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 0,01474355 0,10799413 ! ensheathment of neurons GO:0007272 43 28 1,000 0,01474355 0,10765129 GO:0008366|axon ensheathment, ! T cell activation GO:0042110 134 79 2,000 0,01562222 0,11370605 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01576772 0,11440304 ! alcohol catabolic process GO:0046164 104 80 2,000 0,01615395 0,11683672 ! negative regulation of secretion GO:0051048 49 31 1,000 0,01790459 0,12909268 ! mammary gland development GO:0030879 57 31 1,000 0,01790459 0,12868926 ! segmentation GO:0035282 41 31 1,000 0,01790459 0,12828836 ! metanephros development GO:0001656 58 31 1,000 0,01790459 0,12788995 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01790459 0,12749401 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,01790459 0,12710051 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,01838193 0,1300875 ! sterol metabolic process GO:0016125 120 84 2,000 0,01838193 0,12968846 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 0,01896427 0,1333878 ! neutral lipid metabolic process GO:0006638 41 32 1,000 0,01901643 0,1333469 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01901643 0,13294159 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01901643 0,13253874 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,01901643 0,13213832 ! RNA export from nucleus GO:0006405 44 33 1,000 0,02015663 0,13963931 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02015663 0,13921997 ! ear morphogenesis GO:0042471 42 33 1,000 0,02015663 0,13880314 ! actomyosin structure organization GO:0031032 43 33 1,000 0,02015663 0,1383888 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,02015663 0,13797693 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,02015942 0,13758657 GO:0060538|skeletal muscle organ development, ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,02132478 0,14510946 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,02132478 0,14468141 ! glycerol ether metabolic process GO:0006662 44 34 1,000 0,02132478 0,14425588 ! neuron migration GO:0001764 46 34 1,000 0,02132478 0,14383284 ! female gamete generation GO:0007292 43 34 1,000 0,02132478 0,14341227 ! reproductive developmental process GO:0003006 127 89 2,000 0,02139527 0,14346684 ! leukocyte differentiation GO:0002521 143 90 2,000 0,02202847 0,14728335 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,02252047 0,15013645 ! Rho protein signal transduction GO:0007266 51 35 1,000 0,02252047 0,14970253 ! glycogen metabolic process GO:0005977 48 35 1,000 0,02252047 0,14927111 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,02252047 0,14884217 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 0,02252047 0,14841569 ! cell fate commitment GO:0045165 141 92 2,000 0,02332541 0,15328124 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,02374328 0,15558274 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 0,02374328 0,15514075 ! organic ether metabolic process GO:0018904 46 36 1,000 0,02374328 0,15470125 ! response to xenobiotic stimulus GO:0009410 50 36 1,000 0,02374328 0,15426424 ! glucan metabolic process GO:0044042 49 36 1,000 0,02374328 0,1538297 GO:0006073|cellular glucan metabolic process, ! carbohydrate catabolic process GO:0016052 121 93 2,000 0,02398915 0,15498608 ! regulation of protein secretion GO:0050708 51 37 1,000 0,02499281 0,1610181 ! amino acid activation GO:0043038 52 37 1,000 0,02499281 0,16056833 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of binding GO:0051098 151 95 2,000 0,02534717 0,16239136 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 0,02604144 0,16637589 ! mesenchymal cell development GO:0014031 64 38 1,000 0,02626866 0,16736263 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 1,000 0,02626866 0,1669003 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,02757042 0,17468862 ! male sex differentiation GO:0046661 53 39 1,000 0,02757042 0,17420871 ! developmental growth GO:0048589 62 39 1,000 0,02757042 0,17373143 ! cell growth GO:0016049 61 39 1,000 0,02757042 0,17325675 ! synapse organization GO:0050808 55 39 1,000 0,02757042 0,17278466 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,0281852 0,17615748 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,02889771 0,18012125 ! double-strand break repair GO:0006302 67 40 1,000 0,02889771 0,17963443 ! B cell differentiation GO:0030183 62 40 1,000 0,02889771 0,17915024 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,03025014 0,18703043 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,03025014 0,18652901 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,03025014 0,18603027 ! regulation of JNK cascade GO:0046328 58 41 1,000 0,03025014 0,18553419 ! mitochondrial transport GO:0006839 60 42 1,000 0,03162732 0,19346497 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,03162732 0,1929518 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03274331 0,19923175 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03274331 0,19870608 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03274331 0,19818316 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03274331 0,197663 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03274331 0,19714556 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03274331 0,19663082 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03274331 0,19611876 ! sleep GO:0030431 11 5 0,000 0,03274331 0,19560936 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03274331 0,1951026 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03274331 0,19459846 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03274331 0,19409691 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03274331 0,19359795 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03274331 0,19310154 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03274331 0,19260768 ! tongue development GO:0043586 6 5 0,000 0,03274331 0,19211633 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03274331 0,19162749 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03274331 0,19114112 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03274331 0,19065722 ! cobalt ion transport GO:0006824 9 5 0,000 0,03274331 0,19017576 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03274331 0,18969673 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03274331 0,18922011 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03274331 0,18874587 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03274331 0,18827401 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03274331 0,18780449 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03274331 0,18733732 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03274331 0,18687246 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03274331 0,18640991 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03274331 0,18594964 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03274331 0,18549163 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03274331 0,18503588 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03274331 0,18458236 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03274331 0,18413106 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03274331 0,18368196 ! malate metabolic process GO:0006108 7 5 0,000 0,03274331 0,18323504 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03274331 0,1827903 ! behavioral response to pain GO:0048266 7 5 0,000 0,03274331 0,18234771 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03274331 0,18190725 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03274331 0,18146892 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03274331 0,1810327 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03274331 0,18059857 ! mating behavior GO:0007617 6 5 0,000 0,03274331 0,18016651 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03274331 0,17973652 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03274331 0,17930858 ! rhythmic behavior GO:0007622 12 5 0,000 0,03274331 0,17888267 ! copulation GO:0007620 7 5 0,000 0,03274331 0,17845877 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03274331 0,17803689 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03274331 0,17761699 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03274331 0,17719906 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03274331 0,1767831 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03274331 0,17636909 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03274331 0,17595702 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03274331 0,17554686 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03274331 0,17513861 ! response to protozoan GO:0001562 9 5 0,000 0,03274331 0,17473226 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,03274331 0,17432778 ! lymph vessel development GO:0001945 7 5 0,000 0,03274331 0,17392518 ! endochondral ossification GO:0001958 12 5 0,000 0,03274331 0,17352443 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03274331 0,17312552 ! parathyroid gland development GO:0060017 8 5 0,000 0,03274331 0,17272845 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03274331 0,17233319 ! anagen GO:0042640 6 5 0,000 0,03274331 0,17193973 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03274331 0,17154807 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03274331 0,17115819 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03274331 0,17077007 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03274331 0,17038372 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03274331 0,1699991 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03274331 0,16961622 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03274331 0,16923506 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03274331 0,16885561 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03274331 0,16847786 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03274331 0,16810179 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03274331 0,1677274 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03274331 0,16735467 ! ovulation GO:0030728 6 5 0,000 0,03274331 0,1669836 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03274331 0,16661416 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,03274331 0,16624636 ! response to pH GO:0009268 9 5 0,000 0,03274331 0,16588018 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03274331 0,16551561 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03274331 0,16515264 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03274331 0,16479125 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03274331 0,16443145 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03274331 0,16407321 ! polyol catabolic process GO:0046174 7 5 0,000 0,03274331 0,16371653 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03274331 0,16336139 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03274331 0,1630078 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03274331 0,16265573 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03274331 0,16230518 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03274331 0,16195613 ! urea metabolic process GO:0019627 6 5 0,000 0,03274331 0,16160859 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03274331 0,16126253 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03274331 0,16091795 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03274331 0,16057485 ! neutrophil activation GO:0042119 5 5 0,000 0,03274331 0,1602332 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03274331 0,159893 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03274331 0,15955424 ! response to food GO:0032094 5 5 0,000 0,03274331 0,15921692 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03274331 0,15888102 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03274331 0,15854653 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03274331 0,15821345 ! forebrain neuron development GO:0021884 7 5 0,000 0,03274331 0,15788177 ! melanosome organization GO:0032438 7 5 0,000 0,03274331 0,15755147 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03274331 0,15722255 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03274331 0,15689501 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03274331 0,15656882 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03274331 0,15624399 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03274331 0,1559205 ! nucleoside transport GO:0015858 6 5 0,000 0,03274331 0,15559835 ! nucleoside salvage GO:0043174 7 5 0,000 0,03274331 0,15527753 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03274331 0,15495803 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03274331 0,15463984 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03274331 0,15432296 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03274331 0,15400737 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03274331 0,15369307 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03274331 0,15338005 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03274331 0,1530683 ! depyrimidination GO:0045008 8 5 0,000 0,03274331 0,15275781 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03274331 0,15244859 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03274331 0,15214061 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03274331 0,15183388 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03274331 0,15152838 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03274331 0,1512241 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03274331 0,15092105 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,03274331 0,1506192 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03274331 0,15031857 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03274331 0,15001913 ! monocyte differentiation GO:0030224 8 5 0,000 0,03274331 0,14972088 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03274331 0,14942381 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03274331 0,14912793 ! centrosome duplication GO:0051298 5 5 0,000 0,03274331 0,14883321 ! response to UV-C GO:0010225 6 5 0,000 0,03274331 0,14853965 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03274331 0,14824725 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03274331 0,147956 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03274331 0,14766589 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03274331 0,14737691 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03274331 0,14708907 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03274331 0,14680234 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03274331 0,14651674 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03274331 0,14623224 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03274331 0,14594884 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03274331 0,14566654 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03274331 0,14538533 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03274331 0,14510521 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03274331 0,14482616 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03274331 0,14454818 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03274331 0,14427127 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03274331 0,14399542 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03274331 0,14372062 ! neural tube patterning GO:0021532 6 5 0,000 0,03274331 0,14344686 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03274331 0,14317415 ! histone demethylation GO:0016577 9 5 0,000 0,03274331 0,14290247 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03274331 0,14263182 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03274331 0,1423622 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03274331 0,14209359 ! enteric nervous system development GO:0048484 8 5 0,000 0,03274331 0,14182599 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03274331 0,1415594 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03274331 0,14129381 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03274331 0,14102922 ! transcription termination GO:0006353 8 5 0,000 0,03274331 0,14076561 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03274331 0,14050299 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03274331 0,14024135 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03274331 0,13998067 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,03274331 0,13972097 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03274331 0,13946223 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03274331 0,13920444 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03274331 0,13894761 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03274331 0,13869172 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03274331 0,13843677 ! apical protein localization GO:0045176 6 5 0,000 0,03274331 0,13818276 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03274331 0,13792967 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03274331 0,13767752 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03274331 0,13742628 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03274331 0,13717596 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03274331 0,13692655 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03274331 0,13667804 ! glial cell migration GO:0008347 10 5 0,000 0,03274331 0,13643044 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03274331 0,13618373 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,03274331 0,13593791 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03274331 0,13569298 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03274331 0,13544893 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03274331 0,13520575 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03274331 0,13496345 ! neural plate development GO:0001840 6 5 0,000 0,03274331 0,13472201 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03274331 0,13448143 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03274331 0,13424172 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03274331 0,13400285 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03274331 0,13376484 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,03274331 0,13352766 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03274331 0,13329133 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03274331 0,13305583 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03274331 0,13282117 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03274331 0,13258733 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03274331 0,13235431 ! spindle assembly GO:0051225 5 5 0,000 0,03274331 0,13212211 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03274331 0,13189072 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03274331 0,13166014 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03274331 0,13143037 ! organ regeneration GO:0031100 7 5 0,000 0,03274331 0,1312014 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03274331 0,13097322 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03274331 0,13074584 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03274331 0,13051924 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03274331 0,13029343 GO:0055081|anion homeostasis, ! positive regulation of binding GO:0051099 59 43 1,000 0,03302886 0,13120273 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,03302886 0,13097652 ! response to insulin stimulus GO:0032868 63 43 1,000 0,03302886 0,13075108 ! regulation of action potential GO:0001508 71 44 1,000 0,0344544 0,13615998 ! induction of apoptosis by extracellular signals GO:0008624 74 44 1,000 0,0344544 0,13592643 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,0344544 0,13569368 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,0344544 0,13546173 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,03590355 0,14091835 ! lipoprotein biosynthetic process GO:0042158 67 45 1,000 0,03590355 0,14067829 ! cell maturation GO:0048469 60 45 1,000 0,03590355 0,14043904 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,03737594 0,1459502 ! histone modification GO:0016570 68 46 1,000 0,03737594 0,14570282 ! covalent chromatin modification GO:0016569 75 47 1,000 0,03887122 0,15127546 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,03887122 0,15101993 ! tRNA transcription GO:0009304 11 6 0,000 0,03916327 0,15189802 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03916327 0,1516423 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03916327 0,15138744 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03916327 0,15113344 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03916327 0,15088028 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03916327 0,15062797 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03916327 0,15037651 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03916327 0,15012588 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03916327 0,14987609 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03916327 0,14962712 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03916327 0,14937899 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03916327 0,14913167 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03916327 0,14888517 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03916327 0,14863949 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,03916327 0,14839461 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03916327 0,14815054 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03916327 0,14790727 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03916327 0,1476648 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03916327 0,14742312 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03916327 0,14718224 ! neuron adhesion GO:0007158 9 6 0,000 0,03916327 0,14694213 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03916327 0,14670281 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03916327 0,14646427 ! signal peptide processing GO:0006465 8 6 0,000 0,03916327 0,14622651 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03916327 0,14598951 ! mRNA stabilization GO:0048255 15 6 0,000 0,03916327 0,14575328 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03916327 0,14551782 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03916327 0,14528311 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03916327 0,14504916 ! opsonization GO:0008228 8 6 0,000 0,03916327 0,14481596 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03916327 0,14458351 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03916327 0,14435181 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03916327 0,14412085 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03916327 0,14389062 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03916327 0,14366113 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03916327 0,14343237 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03916327 0,14320434 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03916327 0,14297703 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03916327 0,14275044 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03916327 0,14252457 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03916327 0,14229941 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03916327 0,14207497 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03916327 0,14185123 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03916327 0,14162819 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03916327 0,14140585 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03916327 0,14118421 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03916327 0,14096327 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03916327 0,14074301 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03916327 0,14052345 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03916327 0,14030456 ! thymic T cell selection GO:0045061 12 6 0,000 0,03916327 0,14008636 ! protein lipoylation GO:0009249 10 6 0,000 0,03916327 0,13986883 ! pigment granule organization GO:0048753 11 6 0,000 0,03916327 0,13965198 ! drug transport GO:0015893 6 6 0,000 0,03916327 0,1394358 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03916327 0,13922029 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03916327 0,13900544 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03916327 0,13879126 ! histidine metabolic process GO:0006547 6 6 0,000 0,03916327 0,13857774 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03916327 0,13836487 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03916327 0,13815265 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03916327 0,13794108 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03916327 0,13773017 ! adenohypophysis development GO:0021984 10 6 0,000 0,03916327 0,13751989 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03916327 0,13731026 ! hyperosmotic response GO:0006972 8 6 0,000 0,03916327 0,13710126 ! microtubule nucleation GO:0007020 10 6 0,000 0,03916327 0,1368929 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03916327 0,13668517 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03916327 0,13647807 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03916327 0,1362716 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03916327 0,13606575 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03916327 0,13586053 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,03916327 0,13565592 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03916327 0,13545192 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03916327 0,13524854 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03916327 0,13504577 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03916327 0,13484361 ! purine salvage GO:0043101 8 6 0,000 0,03916327 0,13464205 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03916327 0,13444109 ! organic alcohol transport GO:0015850 9 6 0,000 0,03916327 0,13424073 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03916327 0,13404096 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03916327 0,1338418 ! male sex determination GO:0030238 9 6 0,000 0,03916327 0,13364322 ! carnitine transport GO:0015879 8 6 0,000 0,03916327 0,13344523 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03916327 0,13324782 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03916327 0,133051 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03916327 0,13285476 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03916327 0,1326591 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03916327 0,13246401 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03916327 0,1322695 ! parturition GO:0007567 12 6 0,000 0,03916327 0,13207555 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03916327 0,13188218 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03916327 0,13168937 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03916327 0,13149712 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03916327 0,13130543 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03916327 0,13111431 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03916327 0,13092373 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03916327 0,13073371 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03916327 0,13054424 ! macrophage differentiation GO:0030225 10 6 0,000 0,03916327 0,13035532 ! astrocyte development GO:0014002 14 6 0,000 0,03916327 0,13016695 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03916327 0,12997912 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03916327 0,12979183 ! interaction with symbiont GO:0051702 8 6 0,000 0,03916327 0,12960508 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03916327 0,12941886 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03916327 0,12923318 ! eating behavior GO:0042755 6 6 0,000 0,03916327 0,12904803 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03916327 0,12886342 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03916327 0,12867933 ! response to copper ion GO:0046688 9 6 0,000 0,03916327 0,12849576 ! DNA topological change GO:0006265 8 6 0,000 0,03916327 0,12831272 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03916327 0,1281302 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03916327 0,12794819 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03916327 0,12776671 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03916327 0,12758573 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03916327 0,12740527 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03916327 0,12722532 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03916327 0,12704588 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03916327 0,12686694 ! gas homeostasis GO:0033483 11 6 0,000 0,03916327 0,12668851 ! hair follicle maturation GO:0048820 7 6 0,000 0,03916327 0,12651057 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03916327 0,12633314 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03916327 0,1261562 ! Schwann cell development GO:0014044 14 6 0,000 0,03916327 0,12597976 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03916327 0,12580381 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03916327 0,12562835 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03916327 0,12545338 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03916327 0,1252789 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03916327 0,1251049 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03916327 0,12493138 ! histone ubiquitination GO:0016574 7 6 0,000 0,03916327 0,12475835 ! regulation of meiosis GO:0040020 10 6 0,000 0,03916327 0,12458579 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03916327 0,12441371 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03916327 0,12424211 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03916327 0,12407098 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03916327 0,12390031 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03916327 0,12373012 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03916327 0,1235604 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03916327 0,12339113 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03916327 0,12322234 ! receptor internalization GO:0031623 9 6 0,000 0,03916327 0,123054 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03916327 0,12288612 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03916327 0,1227187 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03916327 0,12255174 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03916327 0,12238523 ! protein deubiquitination GO:0016579 8 6 0,000 0,03916327 0,12221917 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03916327 0,12205356 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03916327 0,1218884 ! axonal fasciculation GO:0007413 9 6 0,000 0,03916327 0,12172369 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03916327 0,12155942 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03916327 0,12139559 ! midbrain development GO:0030901 6 6 0,000 0,03916327 0,1212322 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03916327 0,12106926 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03916327 0,12090675 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03916327 0,12074468 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03916327 0,12058304 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03916327 0,12042183 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03916327 0,12026105 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03916327 0,1201007 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03916327 0,11994078 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03916327 0,11978129 ! adult feeding behavior GO:0008343 6 6 0,000 0,03916327 0,11962222 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03916327 0,11946357 ! blastocyst growth GO:0001832 15 6 0,000 0,03916327 0,11930534 ! pigment granule transport GO:0051904 12 6 0,000 0,03916327 0,11914752 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03916327 0,11899013 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03916327 0,11883315 ! catecholamine transport GO:0051937 7 6 0,000 0,03916327 0,11867659 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03916327 0,11852043 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03916327 0,11836469 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03916327 0,11820935 ! protein prenylation GO:0018342 10 6 0,000 0,03916327 0,11805443 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03916327 0,11789991 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,03916327 0,11774579 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03916327 0,11759207 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03916327 0,11743876 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03916327 0,11728584 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,04038901 0,12079938 ! nuclear export GO:0051168 69 48 1,000 0,04038901 0,12064249 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,04192896 0,1250799 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,04192896 0,12491788 ! ear development GO:0043583 72 50 1,000 0,04349071 0,12940314 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,04349071 0,12923596 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,04349071 0,1290692 ! lipid modification GO:0030258 73 50 1,000 0,04349071 0,12890287 ! positive regulation of growth GO:0045927 67 50 1,000 0,04349071 0,12873698 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,04507391 0,13325192 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,04507391 0,13308087 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,04507391 0,13291025 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,04554099 0,13411561 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,04554099 0,1339441 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,04554099 0,13377304 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,04554099 0,13360241 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,04554099 0,13343221 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04554099 0,13326245 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,04554099 0,13309312 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04554099 0,13292422 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,04554099 0,13275575 ! reproductive behavior GO:0019098 12 7 0,000 0,04554099 0,13258771 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,04554099 0,13242009 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,04554099 0,13225289 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,04554099 0,13208611 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,04554099 0,13191976 ! oligopeptide transport GO:0006857 11 7 0,000 0,04554099 0,13175382 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,04554099 0,1315883 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,04554099 0,1314232 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,04554099 0,13125851 ! RNA methylation GO:0001510 11 7 0,000 0,04554099 0,13109423 ! pericardium development GO:0060039 8 7 0,000 0,04554099 0,13093036 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,04554099 0,1307669 ! fibril organization GO:0043206 13 7 0,000 0,04554099 0,13060385 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,04554099 0,13044121 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04554099 0,13027896 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,04554099 0,13011713 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,04554099 0,12995569 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04554099 0,12979466 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04554099 0,12963402 ! estrogen metabolic process GO:0008210 14 7 0,000 0,04554099 0,12947378 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,04554099 0,12931394 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,04554099 0,12915449 ! chemosensory behavior GO:0007635 9 7 0,000 0,04554099 0,12899543 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,04554099 0,12883676 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,04554099 0,12867849 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,04554099 0,1285206 ! leukocyte degranulation GO:0043299 10 7 0,000 0,04554099 0,1283631 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,04554099 0,12820598 ! reflex GO:0060004 12 7 0,000 0,04554099 0,12804925 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04554099 0,1278929 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,04554099 0,12773694 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04554099 0,12758135 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,04554099 0,12742614 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04554099 0,12727131 ! spinal cord patterning GO:0021511 7 7 0,000 0,04554099 0,12711685 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,04554099 0,12696277 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,04554099 0,12680906 ! adrenal gland development GO:0030325 17 7 0,000 0,04554099 0,12665573 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,04554099 0,12650276 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,04554099 0,12635017 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,04554099 0,12619794 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,04554099 0,12604607 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,04554099 0,12589458 ! endosome organization GO:0007032 10 7 0,000 0,04554099 0,12574344 ! thyroid hormone generation GO:0006590 11 7 0,000 0,04554099 0,12559267 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,04554099 0,12544226 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,04554099 0,12529221 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,04554099 0,12514252 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04554099 0,12499318 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,04554099 0,1248442 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04554099 0,12469558 ! galactose metabolic process GO:0006012 10 7 0,000 0,04554099 0,12454731 ! vesicle fusion GO:0006906 15 7 0,000 0,04554099 0,12439939 ! intracellular pH reduction GO:0051452 10 7 0,000 0,04554099 0,12425182 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,04554099 0,12410461 ! organ growth GO:0035265 11 7 0,000 0,04554099 0,12395774 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,04554099 0,12381121 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,04554099 0,12366504 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,04554099 0,12351921 ! retinol metabolic process GO:0042572 9 7 0,000 0,04554099 0,12337372 ! behavioral fear response GO:0001662 13 7 0,000 0,04554099 0,12322857 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,04554099 0,12308377 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,04554099 0,1229393 ! rRNA modification GO:0000154 12 7 0,000 0,04554099 0,12279518 ! protein heterooligomerization GO:0051291 10 7 0,000 0,04554099 0,12265139 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04554099 0,12250794 ! response to UV-B GO:0010224 11 7 0,000 0,04554099 0,12236482 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,04554099 0,12222204 ! intermediate filament organization GO:0045109 11 7 0,000 0,04554099 0,12207959 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,04554099 0,12193747 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,04554099 0,12179568 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,04554099 0,12165422 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,04554099 0,12151309 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,04554099 0,12137229 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,04554099 0,12123181 ! response to tropane GO:0014073 13 7 0,000 0,04554099 0,12109166 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,04554099 0,12095183 ! melanosome localization GO:0032400 10 7 0,000 0,04554099 0,12081233 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,04554099 0,12067314 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,04554099 0,12053428 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,04554099 0,12039573 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,04554099 0,12025751 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,04554099 0,1201196 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,04554099 0,119982 ! mast cell activation GO:0045576 9 7 0,000 0,04554099 0,11984472 ! multicellular organismal aging GO:0010259 11 7 0,000 0,04554099 0,11970776 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,04554099 0,1195711 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,04554099 0,11943476 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,04554099 0,11929873 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,04554099 0,11916301 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,04554099 0,1190276 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,04554099 0,11889249 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,04554099 0,1187577 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,04554099 0,1186232 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,04554099 0,11848901 ! regulation of lipid transport GO:0032368 13 7 0,000 0,04554099 0,11835513 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,04554099 0,11822154 ! neuroblast proliferation GO:0007405 13 7 0,000 0,04554099 0,11808826 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,04554099 0,11795528 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,04554099 0,1178226 ! diuresis GO:0030146 12 7 0,000 0,04554099 0,11769021 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,04554099 0,11755812 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,04554099 0,11742633 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04554099 0,11729484 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,04554099 0,11716363 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04554099 0,11703272 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04554099 0,11690211 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04554099 0,11677178 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,04554099 0,11664175 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,04554099 0,116512 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,04554099 0,11638254 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,04554099 0,11625337 ! lymph node development GO:0048535 9 7 0,000 0,04554099 0,11612449 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,04554099 0,11599589 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,04554099 0,11586757 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04554099 0,11573954 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,04554099 0,1156118 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,04554099 0,11548433 ! ATP catabolic process GO:0006200 10 7 0,000 0,04554099 0,11535715 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,04554099 0,11523024 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,04554099 0,11510361 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,04554099 0,11497726 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,04554099 0,11485119 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,04554099 0,1147254 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,04554099 0,11459988 ! muscle adaptation GO:0043500 12 7 0,000 0,04554099 0,11447463 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,04554099 0,11434966 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,04554099 0,11422496 ! retina homeostasis GO:0001895 9 7 0,000 0,04554099 0,11410053 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,04554099 0,11397637 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,04554099 0,11385249 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,04554099 0,11372887 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,04554099 0,11360552 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,04554099 0,11348244 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,04554099 0,11335962 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04554099 0,11323707 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,04667822 0,11593941 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,04667822 0,11581434 ! glycerophospholipid biosynthetic process GO:0046474 75 53 1,000 0,04830328 0,11971718 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,04830328 0,11958831 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,04830328 0,11945972 ! kidney development GO:0001822 90 53 1,000 0,04830328 0,11933141 ! cell projection assembly GO:0030031 76 53 1,000 0,04830328 0,11920337 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,04994876 0,12313199 ! detection of external stimulus GO:0009581 66 54 1,000 0,04994876 0,12300016 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,04994876 0,12286861 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05187675 0,12747491 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05187675 0,12733886 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,05187675 0,12720311 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,05187675 0,12706764 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05187675 0,12693246 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05187675 0,12679757 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05187675 0,12666297 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05187675 0,12652865 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05187675 0,12639461 ! phosphate transport GO:0006817 10 8 0,000 0,05187675 0,12626086 ! N-glycan processing GO:0006491 12 8 0,000 0,05187675 0,12612739 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,05187675 0,12599421 ! UTP metabolic process GO:0046051 8 8 0,000 0,05187675 0,1258613 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05187675 0,12572868 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05187675 0,12559633 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,05187675 0,12546426 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05187675 0,12533247 ! succinate metabolic process GO:0006105 14 8 0,000 0,05187675 0,12520096 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05187675 0,12506972 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05187675 0,12493876 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05187675 0,12480807 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,05187675 0,12467765 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05187675 0,12454751 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05187675 0,12441764 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,05187675 0,12428804 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05187675 0,1241587 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,05187675 0,12402964 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05187675 0,12390085 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,05187675 0,12377232 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05187675 0,12364406 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05187675 0,12351606 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,05187675 0,12338833 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05187675 0,12326086 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,05187675 0,12313366 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05187675 0,12300672 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05187675 0,12288004 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,05187675 0,12275362 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05187675 0,12262746 ! melanin metabolic process GO:0006582 12 8 0,000 0,05187675 0,12250155 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05187675 0,12237591 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05187675 0,12225053 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,05187675 0,1221254 ! macrophage activation GO:0042116 12 8 0,000 0,05187675 0,12200053 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05187675 0,12187591 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05187675 0,12175155 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,05187675 0,12162744 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,05187675 0,12150358 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05187675 0,12137997 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,05187675 0,12125662 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05187675 0,12113352 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05187675 0,12101066 ! ruffle organization GO:0031529 11 8 0,000 0,05187675 0,12088806 ! osteoblast development GO:0002076 13 8 0,000 0,05187675 0,1207657 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05187675 0,12064359 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,05187675 0,12052173 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05187675 0,12040012 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,05187675 0,12027874 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,05187675 0,12015762 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,05187675 0,12003673 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05187675 0,11991609 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05187675 0,1197957 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05187675 0,11967554 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,05187675 0,11955563 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,05187675 0,11943595 ! oligodendrocyte development GO:0014003 8 8 0,000 0,05187675 0,11931651 ! segment specification GO:0007379 10 8 0,000 0,05187675 0,11919732 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,05187675 0,11907836 ! cellular extravasation GO:0045123 11 8 0,000 0,05187675 0,11895964 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05187675 0,11884115 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05187675 0,1187229 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05187675 0,11860489 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05187675 0,1184871 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,05187675 0,11836956 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,05187675 0,11825224 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,05187675 0,11813516 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,05187675 0,11801831 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05187675 0,11790169 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05187675 0,11778531 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05187675 0,11766915 ! icosanoid secretion GO:0032309 12 8 0,000 0,05187675 0,11755322 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,05187675 0,11743751 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05187675 0,11732204 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05187675 0,11720679 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05187675 0,11709177 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05187675 0,11697697 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05187675 0,1168624 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,05187675 0,11674806 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05187675 0,11663393 ! sterol catabolic process GO:0016127 9 8 0,000 0,05187675 0,11652003 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05187675 0,11640636 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05187675 0,1162929 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05187675 0,11617966 ! prophase GO:0051324 11 8 0,000 0,05187675 0,11606665 ! S phase GO:0051320 8 8 0,000 0,05187675 0,11595385 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,05187675 0,11584128 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05187675 0,11572892 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05187675 0,11561678 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05187675 0,11550485 ! hormone catabolic process GO:0042447 13 8 0,000 0,05187675 0,11539315 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05187675 0,11528166 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,05187675 0,11517038 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05187675 0,11505932 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05187675 0,11494847 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05187675 0,11483784 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05187675 0,11472742 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05187675 0,11461721 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05187675 0,11450721 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05187675 0,11439743 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05187675 0,11428785 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05187675 0,11417848 ! regulation of embryonic development GO:0045995 16 8 0,000 0,05187675 0,11406933 ! mitochondrion localization GO:0051646 12 8 0,000 0,05187675 0,11396038 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,05187675 0,11385164 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,05329963 0,11686286 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,05329963 0,11675157 ! camera-type eye development GO:0043010 88 57 1,000 0,05500435 0,12037108 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,05500435 0,12025666 ! developmental maturation GO:0021700 75 57 1,000 0,05500435 0,12014246 ! gonad development GO:0008406 79 57 1,000 0,05500435 0,12002847 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0581708 0,12681786 ! regulation of developmental growth GO:0048638 13 9 0,000 0,0581708 0,12669776 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,0581708 0,1265779 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0581708 0,12645826 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,0581708 0,12633885 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,0581708 0,12621966 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,0581708 0,1261007 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,0581708 0,12598196 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0581708 0,12586344 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,0581708 0,12574515 ! GTP metabolic process GO:0046039 9 9 0,000 0,0581708 0,12562708 ! elastic fiber assembly GO:0048251 13 9 0,000 0,0581708 0,12550923 ! social behavior GO:0035176 14 9 0,000 0,0581708 0,1253916 ! regulation of histone modification GO:0031056 11 9 0,000 0,0581708 0,12527419 ! regulation of glycolysis GO:0006110 15 9 0,000 0,0581708 0,12515701 ! response to pain GO:0048265 16 9 0,000 0,0581708 0,12504004 ! protein complex disassembly GO:0043241 17 9 0,000 0,0581708 0,12492329 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0581708 0,12480675 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0581708 0,12469044 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,0581708 0,12457434 ! lung alveolus development GO:0048286 17 9 0,000 0,0581708 0,12445845 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0581708 0,12434279 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,0581708 0,12422733 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0581708 0,12411209 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0581708 0,12399707 ! ventral spinal cord development GO:0021517 11 9 0,000 0,0581708 0,12388226 ! protein targeting to ER GO:0045047 19 9 0,000 0,0581708 0,12376766 ! T cell selection GO:0045058 18 9 0,000 0,0581708 0,12365327 ! endoderm development GO:0007492 12 9 0,000 0,0581708 0,12353909 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0581708 0,12342513 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0581708 0,12331137 ! arginine catabolic process GO:0006527 10 9 0,000 0,0581708 0,12319783 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,0581708 0,12308449 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,0581708 0,12297136 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,0581708 0,12285844 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0581708 0,12274572 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,0581708 0,12263322 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,0581708 0,12252091 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0581708 0,12240882 ! mannose metabolic process GO:0006013 9 9 0,000 0,0581708 0,12229693 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,0581708 0,12218524 ! receptor clustering GO:0043113 15 9 0,000 0,0581708 0,12207376 ! epithelial cell development GO:0002064 10 9 0,000 0,0581708 0,12196248 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,0581708 0,1218514 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0581708 0,12174053 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,0581708 0,12162985 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0581708 0,12151938 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,0581708 0,12140911 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,0581708 0,12129904 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,0581708 0,12118917 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,0581708 0,12107949 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,0581708 0,12097002 ! blastoderm segmentation GO:0007350 11 9 0,000 0,0581708 0,12086074 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0581708 0,12075166 ! DNA ligation GO:0006266 14 9 0,000 0,0581708 0,12064278 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,0581708 0,12053409 ! response to amine stimulus GO:0014075 13 9 0,000 0,0581708 0,1204256 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,0581708 0,1203173 ! erythrocyte development GO:0048821 11 9 0,000 0,0581708 0,1202092 ! renal water homeostasis GO:0003091 14 9 0,000 0,0581708 0,12010129 ! postreplication repair GO:0006301 11 9 0,000 0,0581708 0,11999358 ! mRNA cleavage GO:0006379 13 9 0,000 0,0581708 0,11988606 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,0581708 0,11977873 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,0581708 0,11967159 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,0581708 0,11956465 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,0581708 0,11945789 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,0581708 0,11935133 ! acid secretion GO:0046717 14 9 0,000 0,0581708 0,11924495 ! musculoskeletal movement GO:0050881 11 9 0,000 0,0581708 0,11913877 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,0581708 0,11903277 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,0581708 0,11892697 ! purine base metabolic process GO:0006144 18 9 0,000 0,0581708 0,11882135 ! thymus development GO:0048538 15 9 0,000 0,0581708 0,11871592 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,0581708 0,11861067 ! spleen development GO:0048536 15 9 0,000 0,0581708 0,11850561 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,0581708 0,11840074 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,0581708 0,11829606 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,0581708 0,11819155 ! detection of calcium ion GO:0005513 13 9 0,000 0,0581708 0,11808724 ! blastocyst formation GO:0001825 12 9 0,000 0,0581708 0,1179831 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0581708 0,11787915 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,0581708 0,11777539 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,0581708 0,1176718 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0581708 0,1175684 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0581708 0,11746518 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,0581708 0,11736214 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,0581708 0,11725928 ! prepulse inhibition GO:0060134 14 9 0,000 0,0581708 0,1171566 ! embryonic placenta development GO:0001892 12 9 0,000 0,0581708 0,1170541 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,0581708 0,11695178 ! insulin secretion GO:0030073 17 9 0,000 0,0581708 0,11684964 ! sequestering of metal ion GO:0051238 11 9 0,000 0,0581708 0,11674768 ! response to nicotine GO:0035094 16 9 0,000 0,0581708 0,11664589 ! establishment of cell polarity GO:0030010 12 9 0,000 0,0581708 0,11654428 ! nucleus localization GO:0051647 15 9 0,000 0,0581708 0,11644285 ! regulation of synapse organization GO:0050807 12 9 0,000 0,0581708 0,1163416 ! lung development GO:0030324 94 59 1,000 0,05847074 0,11683989 ! glycerolipid biosynthetic process GO:0045017 85 60 1,000 0,06023177 0,1202544 ! fertilization GO:0009566 68 60 1,000 0,06023177 0,1201501 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,06023177 0,12004599 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,06201092 0,12348496 ! meiosis GO:0007126 96 61 1,000 0,06201092 0,12337814 GO:0051327|M phase of meiotic cell cycle, ! homeostasis of number of cells GO:0048872 84 61 1,000 0,06201092 0,1232715 ! neurotransmitter transport GO:0006836 81 62 1,000 0,0638079 0,12673416 ! respiratory tube development GO:0030323 99 62 1,000 0,0638079 0,12662481 ! meiotic cell cycle GO:0051321 97 62 1,000 0,0638079 0,12651565 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,06442343 0,12762609 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,06442343 0,12751625 ! neuron fate specification GO:0048665 11 10 0,000 0,06442343 0,12740661 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,06442343 0,12729715 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,06442343 0,12718788 ! thyroid gland development GO:0030878 19 10 0,000 0,06442343 0,1270788 ! synapsis GO:0007129 13 10 0,000 0,06442343 0,12696991 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,06442343 0,1268612 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,06442343 0,12675268 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,06442343 0,12664435 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,06442343 0,1265362 ! sulfate transport GO:0008272 12 10 0,000 0,06442343 0,12642823 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,06442343 0,12632045 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,06442343 0,12621285 ! androgen metabolic process GO:0008209 13 10 0,000 0,06442343 0,12610543 ! hippocampus development GO:0021766 19 10 0,000 0,06442343 0,1259982 ! blood vessel remodeling GO:0001974 21 10 0,000 0,06442343 0,12589115 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,06442343 0,12578428 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,06442343 0,1256776 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,06442343 0,12557109 ! pathogenesis GO:0009405 13 10 0,000 0,06442343 0,12546476 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,06442343 0,12535862 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06442343 0,12525265 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,06442343 0,12514686 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,06442343 0,12504125 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,06442343 0,12493582 ! melanocyte differentiation GO:0030318 15 10 0,000 0,06442343 0,12483057 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,06442343 0,12472549 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,06442343 0,12462059 ! B cell proliferation GO:0042100 14 10 0,000 0,06442343 0,12451587 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,06442343 0,12441132 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,06442343 0,12430695 ! forebrain cell migration GO:0021885 17 10 0,000 0,06442343 0,12420275 ! lipid digestion GO:0044241 15 10 0,000 0,06442343 0,12409873 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,06442343 0,12399488 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,06442343 0,12389121 ! UV protection GO:0009650 14 10 0,000 0,06442343 0,12378771 ! entry into host cell GO:0030260 20 10 0,000 0,06442343 0,12368438 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,06442343 0,12358122 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,06442343 0,12347824 ! negative regulation of ossification GO:0030279 19 10 0,000 0,06442343 0,12337542 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,06442343 0,12327278 ! regulation of bone resorption GO:0045124 24 10 0,000 0,06442343 0,12317031 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,06442343 0,12306801 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,06442343 0,12296588 ! regulation of organ growth GO:0046620 11 10 0,000 0,06442343 0,12286392 ! response to dsRNA GO:0043331 18 10 0,000 0,06442343 0,12276213 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,06442343 0,1226605 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06442343 0,12255904 ! embryonic axis specification GO:0000578 12 10 0,000 0,06442343 0,12245776 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,06442343 0,12235664 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,06442343 0,12225568 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,06442343 0,12215489 ! cranial nerve development GO:0021545 12 10 0,000 0,06442343 0,12205427 ! fucose catabolic process GO:0019317 16 10 0,000 0,06442343 0,12195381 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,06442343 0,12185352 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,06442343 0,1217534 ! protein sumoylation GO:0016925 12 10 0,000 0,06442343 0,12165344 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,06442343 0,12155364 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06442343 0,121454 ! zymogen activation GO:0031638 14 10 0,000 0,06442343 0,12135453 ! salivary gland development GO:0007431 22 10 0,000 0,06442343 0,12125523 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06442343 0,12115608 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,06442343 0,1210571 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,06442343 0,12095827 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,06442343 0,12085961 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,06442343 0,12076111 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,06442343 0,12066277 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06442343 0,12056459 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,06442343 0,12046657 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,06442343 0,12036871 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,06442343 0,12027101 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,06442343 0,12017347 ! detection of bacterium GO:0016045 10 10 0,000 0,06442343 0,12007608 ! embryonic gut development GO:0048566 11 10 0,000 0,06442343 0,11997885 ! activation of innate immune response GO:0002218 10 10 0,000 0,06442343 0,11988178 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 0,06442343 0,11978487 ! developmental induction GO:0031128 13 10 0,000 0,06442343 0,11968811 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,06442343 0,11959151 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,06442343 0,11949507 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,06442343 0,11939878 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,06442343 0,11930265 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,06562237 0,12142515 ! regulation of lipase activity GO:0060191 109 63 1,000 0,06562237 0,12132754 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,06745405 0,1246139 ! respiratory system development GO:0060541 100 64 1,000 0,06745405 0,12451389 ! B cell activation GO:0042113 104 65 1,000 0,06930262 0,1278236 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,06930262 0,12772117 ! rRNA transcription GO:0009303 17 11 0,000 0,0706349 0,13007228 ! respiratory burst GO:0045730 14 11 0,000 0,0706349 0,12996822 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,0706349 0,12986433 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,0706349 0,1297606 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,0706349 0,12965704 ! virus-host interaction GO:0019048 17 11 0,000 0,0706349 0,12955365 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,0706349 0,12945042 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,0706349 0,12934735 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,0706349 0,12924445 ! RNA polyadenylation GO:0043631 19 11 0,000 0,0706349 0,12914171 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,0706349 0,12903914 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,0706349 0,12893673 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,0706349 0,12883448 ! T cell proliferation GO:0042098 20 11 0,000 0,0706349 0,12873239 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,0706349 0,12863046 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,0706349 0,1285287 ! bone resorption GO:0045453 16 11 0,000 0,0706349 0,1284271 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,0706349 0,12832565 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,0706349 0,12822437 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,0706349 0,12812325 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,0706349 0,12802228 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,0706349 0,12792148 ! syncytium formation GO:0006949 15 11 0,000 0,0706349 0,12782083 ! plasma membrane organization GO:0007009 18 11 0,000 0,0706349 0,12772034 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,0706349 0,12762001 ! focal adhesion formation GO:0048041 24 11 0,000 0,0706349 0,12751984 ! mitotic spindle organization GO:0007052 15 11 0,000 0,0706349 0,12741982 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,0706349 0,12731997 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,0706349 0,12722026 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,0706349 0,12712072 ! adult heart development GO:0007512 11 11 0,000 0,0706349 0,12702133 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,0706349 0,12692209 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,0706349 0,12682301 ! temperature homeostasis GO:0001659 16 11 0,000 0,0706349 0,12672408 ! L-glutamate transport GO:0015813 16 11 0,000 0,0706349 0,12662531 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,0706349 0,1265267 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,0706349 0,12642823 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,0706349 0,12632992 ! stem cell development GO:0048864 29 11 0,000 0,0706349 0,12623176 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,0706349 0,12613376 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,0706349 0,1260359 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,0706349 0,1259382 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,0706349 0,12584065 ! vasoconstriction GO:0042310 15 11 0,000 0,0706349 0,12574325 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,0706349 0,125646 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,0706349 0,1255489 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,0706349 0,12545195 ! ribosome assembly GO:0042255 13 11 0,000 0,0706349 0,12535515 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,0706349 0,1252585 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,0706349 0,125162 ! chromatin silencing GO:0006342 19 11 0,000 0,0706349 0,12506565 ! nucleosome positioning GO:0016584 13 11 0,000 0,0706349 0,12496944 ! regulation of isotype switching GO:0045191 19 11 0,000 0,0706349 0,12487339 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,0706349 0,12477748 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,0706349 0,12468172 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,0706349 0,1245861 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,0706349 0,12449063 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,0706349 0,12439531 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,0706349 0,12430014 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,0706349 0,1242051 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,0706349 0,12411022 ! male genitalia development GO:0030539 13 11 0,000 0,0706349 0,12401548 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,0706349 0,12392088 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,0706349 0,12382643 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,0706349 0,12373212 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,0706349 0,12363796 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,0706349 0,12354394 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,0706349 0,12345006 ! defense response to fungus GO:0050832 12 11 0,000 0,0706349 0,12335632 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,0706349 0,12326273 ! lysogeny GO:0030069 18 11 0,000 0,0706349 0,12316928 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,0706349 0,12307597 ! acrosome reaction GO:0007340 13 11 0,000 0,0706349 0,1229828 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,07116779 0,12381688 ! axon guidance GO:0007411 99 66 1,000 0,07116779 0,12372329 ! regulation of immune effector process GO:0002697 101 66 1,000 0,07116779 0,12362984 ! learning or memory GO:0007611 123 68 1,000 0,07494672 0,1300962 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,07494672 0,12999809 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 0,07494672 0,12990012 ! lactation GO:0007595 20 12 0,000 0,07680549 0,13302156 ! reproductive cellular process GO:0048610 14 12 0,000 0,07680549 0,13292147 ! tRNA modification GO:0006400 14 12 0,000 0,07680549 0,13282153 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,07680549 0,13272174 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,07680549 0,13262209 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,07680549 0,1325226 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,07680549 0,13242326 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,07680549 0,13232407 ! non-recombinational repair GO:0000726 19 12 0,000 0,07680549 0,13222502 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,07680549 0,13212613 ! peroxisomal transport GO:0043574 21 12 0,000 0,07680549 0,13202738 ! cartilage condensation GO:0001502 18 12 0,000 0,07680549 0,13192878 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,07680549 0,13183032 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,07680549 0,13173201 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,07680549 0,13163385 ! heart looping GO:0001947 15 12 0,000 0,07680549 0,13153584 ! palate development GO:0060021 15 12 0,000 0,07680549 0,13143797 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,07680549 0,13134025 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,07680549 0,13124267 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,07680549 0,13114523 ! arginine metabolic process GO:0006525 13 12 0,000 0,07680549 0,13104795 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,07680549 0,1309508 ! methionine metabolic process GO:0006555 13 12 0,000 0,07680549 0,1308538 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,07680549 0,13075694 ! Golgi organization GO:0007030 18 12 0,000 0,07680549 0,13066023 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,07680549 0,13056366 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,07680549 0,13046723 ! monoamine transport GO:0015844 13 12 0,000 0,07680549 0,13037094 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07680549 0,1302748 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,07680549 0,1301788 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,07680549 0,13008294 ! L-amino acid transport GO:0015807 20 12 0,000 0,07680549 0,12998722 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,07680549 0,12989164 GO:0002717|positive regulation of natural killer cell mediated immunity, ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,07680549 0,1297962 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07680549 0,1297009 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,07680549 0,12960574 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,07680549 0,12951073 ! cerebellum development GO:0021549 13 12 0,000 0,07680549 0,12941585 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,07680549 0,12932111 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,07680549 0,1292265 ! histone methylation GO:0016571 15 12 0,000 0,07680549 0,12913204 ! autonomic nervous system development GO:0048483 23 12 0,000 0,07680549 0,12903771 ! gland morphogenesis GO:0022612 23 12 0,000 0,07680549 0,12894353 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,07680549 0,12884947 ! regulation of epidermis development GO:0045682 17 12 0,000 0,07680549 0,12875556 ! intestinal absorption GO:0050892 19 12 0,000 0,07680549 0,12866178 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,07680549 0,12856814 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,07680549 0,12847464 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,07680549 0,12838127 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,07680549 0,12828804 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,07680549 0,12819494 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,07680549 0,12810198 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,07680549 0,12800915 ! microspike assembly GO:0030035 23 12 0,000 0,07680549 0,12791646 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,07680549 0,1278239 ! response to cold GO:0009409 14 12 0,000 0,07680549 0,12773148 ! response to drug GO:0042493 108 69 1,000 0,07685991 0,12772961 ! eye development GO:0001654 111 70 1,000 0,07878851 0,13084013 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,07878851 0,13074573 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,08073226 0,1338747 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,08269087 0,13702378 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,08269087 0,13692513 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,08293546 0,13723134 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,08293546 0,13713268 ! cGMP metabolic process GO:0046068 16 13 0,000 0,08293546 0,13703417 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,08293546 0,13693579 ! water transport GO:0006833 17 13 0,000 0,08293546 0,13683756 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,08293546 0,13673947 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,08293546 0,13664152 ! lipid localization GO:0010876 24 13 0,000 0,08293546 0,13654371 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,08293546 0,13644604 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,08293546 0,13634851 ! organelle fusion GO:0048284 28 13 0,000 0,08293546 0,13625111 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,08293546 0,13615386 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,08293546 0,13605675 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,08293546 0,13595977 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,08293546 0,13586293 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,08293546 0,13576623 ! response to hexose stimulus GO:0009746 19 13 0,000 0,08293546 0,13566967 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glutamate metabolic process GO:0006536 18 13 0,000 0,08293546 0,13557325 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,08293546 0,13547696 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,08293546 0,13538081 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,08293546 0,13528479 ! NAD metabolic process GO:0019674 21 13 0,000 0,08293546 0,13518892 ! exocrine system development GO:0035272 27 13 0,000 0,08293546 0,13509317 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,08293546 0,13499756 ! bone mineralization GO:0030282 15 13 0,000 0,08293546 0,13490209 ! regulation of exocytosis GO:0017157 17 13 0,000 0,08293546 0,13480676 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,08293546 0,13471155 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,08293546 0,13461649 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,08293546 0,13452155 ! genitalia development GO:0048806 15 13 0,000 0,08293546 0,13442675 ! cellular pigmentation GO:0033059 24 13 0,000 0,08293546 0,13433208 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,08293546 0,13423755 ! cofactor transport GO:0051181 19 13 0,000 0,08293546 0,13414315 ! NADP metabolic process GO:0006739 18 13 0,000 0,08293546 0,13404888 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,08293546 0,13395475 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,08293546 0,13386074 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08293546 0,13376687 ! gas transport GO:0015669 18 13 0,000 0,08293546 0,13367313 ! regulation of RNA stability GO:0043487 28 13 0,000 0,08293546 0,13357952 ! heme biosynthetic process GO:0006783 20 13 0,000 0,08293546 0,13348605 ! regulation of axon extension GO:0030516 23 13 0,000 0,08293546 0,1333927 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,08293546 0,13329948 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,08293546 0,1332064 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,08293546 0,13311344 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,08293546 0,13302061 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,08293546 0,13292792 ! negative regulation of transport GO:0051051 116 73 1,000 0,08466406 0,135604 ! cellular lipid catabolic process GO:0044242 105 73 1,000 0,08466406 0,13550963 ! phospholipid biosynthetic process GO:0008654 102 74 1,000 0,08665155 0,13859428 ! protein import into nucleus GO:0006606 118 74 1,000 0,08665155 0,13849797 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,08665155 0,13840179 ! nuclear import GO:0051170 121 75 1,000 0,08865308 0,14150041 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,08902508 0,14199561 ! superoxide anion generation GO:0042554 18 14 0,000 0,08902508 0,14189721 ! neuron maturation GO:0042551 21 14 0,000 0,08902508 0,14179894 ! regulation of S phase GO:0033261 18 14 0,000 0,08902508 0,14170081 ! myotube differentiation GO:0014902 21 14 0,000 0,08902508 0,14160282 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,08902508 0,14150496 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,08902508 0,14140723 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,08902508 0,14130964 ! inositol metabolic process GO:0006020 20 14 0,000 0,08902508 0,14121219 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,08902508 0,14111487 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,08902508 0,14101768 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,08902508 0,14092063 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,08902508 0,14082371 ! gene silencing by RNA GO:0031047 20 14 0,000 0,08902508 0,14072692 ! response to cAMP GO:0051591 19 14 0,000 0,08902508 0,14063027 ! limbic system development GO:0021761 25 14 0,000 0,08902508 0,14053375 ! startle response GO:0001964 21 14 0,000 0,08902508 0,14043736 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,08902508 0,14034111 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,08902508 0,14024498 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,08902508 0,14014899 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,08902508 0,14005313 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,08902508 0,1399574 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,08902508 0,1398618 ! glycine metabolic process GO:0006544 22 14 0,000 0,08902508 0,13976633 ! pituitary gland development GO:0021983 23 14 0,000 0,08902508 0,13967099 ! lysosomal transport GO:0007041 20 14 0,000 0,08902508 0,13957578 ! regulation of heart rate GO:0002027 23 14 0,000 0,08902508 0,1394807 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,08902508 0,13938575 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,08902508 0,13929093 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,08902508 0,13919624 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,08902508 0,13910168 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,08902508 0,13900725 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,08902508 0,13891294 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,08902508 0,13881876 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,08902508 0,13872471 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08902508 0,13863079 ! mRNA splice site selection GO:0006376 26 14 0,000 0,08902508 0,13853699 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,08902508 0,13844332 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,08902508 0,13834978 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,08902508 0,13825636 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,08902508 0,13816307 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,08902508 0,13806991 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,08902508 0,13797687 ! muscle maintenance GO:0046716 19 14 0,000 0,08902508 0,13788396 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,08902508 0,13779117 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,08902508 0,1376985 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,08902508 0,13760596 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,08902508 0,13751355 ! cell killing GO:0001906 20 14 0,000 0,08902508 0,13742126 ! cilium assembly GO:0042384 20 14 0,000 0,08902508 0,13732909 ! peptide hormone secretion GO:0030072 23 14 0,000 0,08902508 0,13723705 ! tRNA metabolic process GO:0006399 95 76 1,000 0,09066837 0,13967666 ! protein ubiquitination GO:0016567 125 77 1,000 0,09269715 0,14270646 ! metencephalon development GO:0022037 19 15 0,000 0,0950746 0,14626862 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,0950746 0,14617084 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,0950746 0,1460732 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,0950746 0,14597569 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,0950746 0,14587831 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,0950746 0,14578105 ! lipid phosphorylation GO:0046834 23 15 0,000 0,0950746 0,14568393 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,0950746 0,14558694 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,0950746 0,14549007 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,0950746 0,14539334 ! bile acid metabolic process GO:0008206 22 15 0,000 0,0950746 0,14529673 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,0950746 0,14520025 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,0950746 0,1451039 ! adult walking behavior GO:0007628 25 15 0,000 0,0950746 0,14500768 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,0950746 0,14491158 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,0950746 0,14481562 ! myoblast differentiation GO:0045445 27 15 0,000 0,0950746 0,14471978 ! centrosome cycle GO:0007098 16 15 0,000 0,0950746 0,14462406 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,0950746 0,14452847 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,0950746 0,14443301 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,0950746 0,14433768 ! cerebral cortex development GO:0021987 29 15 0,000 0,0950746 0,14424247 ! response to osmotic stress GO:0006970 22 15 0,000 0,0950746 0,14414738 ! vesicle coating GO:0006901 25 15 0,000 0,0950746 0,14405242 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,0950746 0,14395759 ! DNA integration GO:0015074 22 15 0,000 0,0950746 0,14386288 ! peptide secretion GO:0002790 27 15 0,000 0,0950746 0,1437683 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,0950746 0,14367384 ! regulation of vasodilation GO:0042312 24 15 0,000 0,0950746 0,1435795 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,0950746 0,14348529 ! neuron recognition GO:0008038 22 15 0,000 0,0950746 0,1433912 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,0950746 0,14329723 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,0950746 0,14320339 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,0950746 0,14310967 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,0950746 0,14301608 ! biomineral formation GO:0031214 18 15 0,000 0,0950746 0,1429226 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,0950746 0,14282925 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,0950746 0,14273602 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,0950746 0,14264291 ! dopamine metabolic process GO:0042417 30 15 0,000 0,0950746 0,14254992 ! organic cation transport GO:0015695 19 15 0,000 0,0950746 0,14245706 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,0950746 0,14236431 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,0950746 0,14227169 ! defense response to virus GO:0051607 27 15 0,000 0,0950746 0,14217918 ! peptide hormone processing GO:0016486 19 15 0,000 0,0950746 0,1420868 ! protein localization in nucleus GO:0034504 133 80 1,000 0,09886185 0,14765082 ! regulation of GTPase activity GO:0043087 129 80 1,000 0,09886185 0,147555 ! forebrain development GO:0030900 131 80 1,000 0,09886185 0,14745931 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,10094201 0,15046443 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,10094201 0,15036698 GO:0002696|positive regulation of leukocyte activation, ! protein secretion GO:0009306 27 16 0,000 0,1010843 0,15048148 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,1010843 0,15038414 ! hormone secretion GO:0046879 25 16 0,000 0,1010843 0,15028693 ! bone remodeling GO:0046849 24 16 0,000 0,1010843 0,15018984 ! endothelial cell migration GO:0043542 22 16 0,000 0,1010843 0,15009289 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,1010843 0,14999605 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,1010843 0,14989934 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,1010843 0,14980276 ! glial cell development GO:0021782 24 16 0,000 0,1010843 0,1497063 ! patterning of blood vessels GO:0001569 24 16 0,000 0,1010843 0,14960996 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,1010843 0,14951375 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,1010843 0,14941766 ! protein polyubiquitination GO:0000209 26 16 0,000 0,1010843 0,14932169 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,1010843 0,14922585 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,1010843 0,14913013 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,1010843 0,14903454 ! regulation of protein binding GO:0043393 27 16 0,000 0,1010843 0,14893906 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,1010843 0,14884371 ! protein export from nucleus GO:0006611 24 16 0,000 0,1010843 0,14874848 ! negative regulation of immune response GO:0050777 28 16 0,000 0,1010843 0,14865338 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,1010843 0,14855839 ! DNA replication initiation GO:0006270 25 16 0,000 0,1010843 0,14846352 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,1010843 0,14836878 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,1010843 0,14827416 ! diencephalon development GO:0021536 25 16 0,000 0,1010843 0,14817966 ! neural crest cell migration GO:0001755 24 16 0,000 0,1010843 0,14808527 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,1010843 0,14799101 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,1010843 0,14789687 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,1010843 0,14780285 ! steroid catabolic process GO:0006706 22 16 0,000 0,1010843 0,14770894 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,1010843 0,14761516 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,1010843 0,1475215 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,1010843 0,14742795 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,1010843 0,14733452 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,1010843 0,14724122 ! sperm-egg recognition GO:0035036 16 16 0,000 0,1010843 0,14714802 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,1010843 0,14705495 ! nerve development GO:0021675 18 16 0,000 0,1010843 0,146962 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,1010843 0,14686916 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,1010843 0,14677644 ! ossification GO:0001503 134 82 1,000 0,10303436 0,14951359 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,10303436 0,14941932 ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,10513868 0,15237489 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,10705442 0,15505363 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,10705442 0,15495605 ! negative regulation of defense response GO:0031348 19 17 0,000 0,10705442 0,1548586 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,10705442 0,15476126 ! glycerol metabolic process GO:0006071 20 17 0,000 0,10705442 0,15466405 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,10705442 0,15456696 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,10705442 0,15446999 ! signal complex assembly GO:0007172 29 17 0,000 0,10705442 0,15437315 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,10705442 0,15427642 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,10705442 0,15417982 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,10705442 0,15408333 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,10705442 0,15398697 ! memory GO:0007613 25 17 0,000 0,10705442 0,15389073 ! keratinization GO:0031424 17 17 0,000 0,10705442 0,15379461 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,10705442 0,15369861 ! retinoid metabolic process GO:0001523 22 17 0,000 0,10705442 0,15360273 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,10705442 0,15350696 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,10705442 0,15341132 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,10705442 0,1533158 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,10705442 0,15322039 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,10705442 0,15312511 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,10705442 0,15302994 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,10705442 0,15293489 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,10705442 0,15283996 ! membrane budding GO:0006900 29 17 0,000 0,10705442 0,15274514 ! heme metabolic process GO:0042168 27 17 0,000 0,10705442 0,15265045 ! actin filament bundle formation GO:0051017 26 17 0,000 0,10705442 0,15255587 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,10705442 0,1524614 ! body fluid secretion GO:0007589 27 17 0,000 0,10705442 0,15236706 ! stem cell differentiation GO:0048863 36 17 0,000 0,10705442 0,15227283 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,10705442 0,15217872 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,10705442 0,15208472 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,10705442 0,15199085 ! sensory perception of pain GO:0019233 23 17 0,000 0,10705442 0,15189708 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,10705442 0,15180343 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,10705442 0,1517099 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,10705442 0,15161648 ! synaptogenesis GO:0007416 24 17 0,000 0,10705442 0,15152318 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,10705442 0,15142999 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,10705442 0,15133692 ! cell-cell junction organization GO:0045216 25 17 0,000 0,10705442 0,15124396 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,10705442 0,15115112 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,10705442 0,15105839 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,10705442 0,15096577 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,10705442 0,15087327 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,10705442 0,15078088 ! rRNA metabolic process GO:0016072 107 85 1,000 0,10938217 0,15396512 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 1,000 0,10938217 0,15387095 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,10938217 0,15377689 ! regulation of membrane potential GO:0042391 128 85 1,000 0,10938217 0,15368296 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,10938217 0,15358913 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,11298524 0,15855158 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,11298524 0,1584549 ! positive regulation of translation GO:0045727 28 18 0,000 0,11298524 0,15835834 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,11298524 0,1582619 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,11298524 0,15816558 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,11298524 0,15806937 ! cAMP metabolic process GO:0046058 33 18 0,000 0,11298524 0,15797328 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,11298524 0,1578773 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,11298524 0,15778145 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,11298524 0,15768571 ! axis specification GO:0009798 26 18 0,000 0,11298524 0,15759008 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,11298524 0,15749457 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,11298524 0,15739918 ! pancreas development GO:0031016 26 18 0,000 0,11298524 0,1573039 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,11298524 0,15720874 ! glutamine metabolic process GO:0006541 23 18 0,000 0,11298524 0,15711369 ! response to retinoic acid GO:0032526 25 18 0,000 0,11298524 0,15701876 ! pigmentation during development GO:0048066 31 18 0,000 0,11298524 0,15692394 ! central nervous system neuron development GO:0021954 30 18 0,000 0,11298524 0,15682924 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,11298524 0,15673465 ! fucose metabolic process GO:0006004 26 18 0,000 0,11298524 0,15664017 ! response to fungus GO:0009620 19 18 0,000 0,11298524 0,15654581 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,11298524 0,15645156 ! heart process GO:0003015 27 18 0,000 0,11298524 0,15635743 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,11298524 0,15626341 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,11298524 0,1561695 ! visual learning GO:0008542 35 18 0,000 0,11298524 0,1560757 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,11298524 0,15598202 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,11298524 0,15588845 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,11298524 0,15579499 ! vitamin transport GO:0051180 24 18 0,000 0,11298524 0,15570164 ! hormone transport GO:0009914 27 18 0,000 0,11298524 0,15560841 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,11298524 0,15551529 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,11298524 0,15542228 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,11298524 0,15532937 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,11298524 0,15523659 ! cell-cell recognition GO:0009988 20 18 0,000 0,11298524 0,15514391 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,11298524 0,15505134 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,11298524 0,15495888 ! regulation of glucose import GO:0046324 21 18 0,000 0,11298524 0,15486653 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,11298524 0,1547743 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,11298524 0,15468217 ! establishment of RNA localization GO:0051236 128 88 1,000 0,11583098 0,15848379 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 1,000 0,11583098 0,15838957 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,11800192 0,16126227 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,118877 0,16236169 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,118877 0,16226534 ! positive regulation of ossification GO:0045778 30 19 0,000 0,118877 0,16216909 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,118877 0,16207297 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,118877 0,16197695 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,118877 0,16188105 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,118877 0,16178526 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,118877 0,16168959 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,118877 0,16159403 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,118877 0,16149858 ! sensory perception of taste GO:0050909 23 19 0,000 0,118877 0,16140324 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,118877 0,16130802 ! smooth muscle contraction GO:0006939 36 19 0,000 0,118877 0,16121291 ! peroxisome organization GO:0007031 29 19 0,000 0,118877 0,16111791 ! digestive system process GO:0022600 30 19 0,000 0,118877 0,16102302 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,118877 0,16092825 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,118877 0,16083358 ! response to vitamin A GO:0033189 26 19 0,000 0,118877 0,16073903 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,118877 0,16064459 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,118877 0,16055026 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,118877 0,16045604 ! plasma membrane fusion GO:0045026 23 19 0,000 0,118877 0,16036193 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,118877 0,16026793 ! cytolysis GO:0019835 20 19 0,000 0,118877 0,16017404 ! renal system process GO:0003014 35 19 0,000 0,118877 0,16008027 ! vasodilation GO:0042311 33 19 0,000 0,118877 0,1599866 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,118877 0,15989304 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,118877 0,15979959 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,118877 0,15970625 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,118877 0,15961301 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,118877 0,15951989 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,118877 0,15942688 ! sarcomere organization GO:0045214 23 19 0,000 0,118877 0,15933397 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,118877 0,15924117 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,118877 0,15914848 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,118877 0,1590559 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,118877 0,15896343 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,118877 0,15887106 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,118877 0,1587788 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,118877 0,15868665 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,12018313 0,16033712 ! RNA localization GO:0006403 135 91 1,000 0,1223744 0,16316586 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,12472996 0,16621026 ! iron ion transport GO:0006826 37 20 0,000 0,12472996 0,16611402 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,12472996 0,16601789 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,12472996 0,16592187 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,12472996 0,16582596 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,12472996 0,16573016 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,12472996 0,16563447 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,12472996 0,1655389 ! spinal cord development GO:0021510 31 20 0,000 0,12472996 0,16544343 ! response to ethanol GO:0045471 37 20 0,000 0,12472996 0,16534807 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,12472996 0,16525283 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,12472996 0,16515769 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,12472996 0,16506266 ! chromosome condensation GO:0030261 31 20 0,000 0,12472996 0,16496774 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,12472996 0,16487293 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,12472996 0,16477823 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,12472996 0,16468364 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,12472996 0,16458916 ! pallium development GO:0021543 38 20 0,000 0,12472996 0,16449479 ! DNA modification GO:0006304 28 20 0,000 0,12472996 0,16440052 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,12472996 0,16430636 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,12472996 0,16421231 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,12472996 0,16411837 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,12472996 0,16402453 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,12472996 0,1639308 ! collagen catabolic process GO:0030574 25 20 0,000 0,12472996 0,16383718 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,12472996 0,16374367 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,12472996 0,16365026 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,12472996 0,16355696 ! alditol metabolic process GO:0019400 24 20 0,000 0,12472996 0,16346376 ! actin filament-based movement GO:0030048 34 20 0,000 0,12472996 0,16337068 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,12678617 0,16596938 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,13054437 0,17079184 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,13054437 0,17069475 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,13054437 0,17059776 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,13054437 0,17050089 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,13054437 0,17040412 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,13054437 0,17030747 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,13054437 0,17021092 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,13054437 0,17011448 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,13054437 0,17001815 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,13054437 0,16992194 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,13054437 0,16982583 ! vesicle docking GO:0048278 27 21 0,000 0,13054437 0,16972983 ! phototransduction GO:0007602 25 21 0,000 0,13054437 0,16963393 ! visual behavior GO:0007632 39 21 0,000 0,13054437 0,16953815 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,13054437 0,16944247 ! ovarian follicle development GO:0001541 30 21 0,000 0,13054437 0,1693469 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,13054437 0,16925144 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,13054437 0,16915609 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,13054437 0,16906085 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,13054437 0,16896571 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,13054437 0,16887068 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,13054437 0,16877575 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,13054437 0,16868093 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,13054437 0,16858622 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,13054437 0,16849162 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,13054437 0,16839712 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,13054437 0,16830273 ! fatty acid transport GO:0015908 30 21 0,000 0,13054437 0,16820844 ! immunoglobulin production GO:0002377 33 21 0,000 0,13054437 0,16811426 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,13054437 0,16802018 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,13054437 0,16792621 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,13054437 0,16783234 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,13054437 0,16773858 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,13054437 0,16764493 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,13054437 0,16755137 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,13054437 0,16745793 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,13054437 0,16736458 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,13054437 0,16727134 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,13054437 0,16717821 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,13054437 0,16708518 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,13054437 0,16699225 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,13054437 0,16689942 ! angiogenesis GO:0001525 149 95 1,000 0,13123547 0,16768976 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,13347364 0,17045495 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,13347364 0,17036036 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,13347364 0,17026587 ! protein maturation GO:0051604 129 96 1,000 0,13347364 0,17017149 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,1363205 0,17370479 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,1363205 0,1736086 ! viral genome replication GO:0019079 29 22 0,000 0,1363205 0,17351253 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,1363205 0,17341656 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,1363205 0,1733207 ! leukocyte adhesion GO:0007159 38 22 0,000 0,1363205 0,17322494 ! molting cycle process GO:0022404 40 22 0,000 0,1363205 0,17312929 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,1363205 0,17303374 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,1363205 0,1729383 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,1363205 0,17284297 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,1363205 0,17274774 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,1363205 0,17265261 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,1363205 0,17255759 ! lysosome organization GO:0007040 37 22 0,000 0,1363205 0,17246267 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,1363205 0,17236786 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,1363205 0,17227315 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,1363205 0,17217855 ! regulation of behavior GO:0050795 38 22 0,000 0,1363205 0,17208405 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,1363205 0,17198965 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,1363205 0,17189536 ! membrane depolarization GO:0051899 35 22 0,000 0,1363205 0,17180117 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,1363205 0,17170709 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,1363205 0,1716131 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,1363205 0,17151922 ! blastocyst development GO:0001824 37 22 0,000 0,1363205 0,17142545 ! neural tube closure GO:0001843 33 22 0,000 0,1363205 0,17133177 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,1363205 0,1712382 ! extracellular structure organization GO:0043062 156 99 1,000 0,14023968 0,17606511 ! protein import GO:0017038 156 99 1,000 0,14023968 0,17596905 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,14205857 0,17815415 ! neuron fate commitment GO:0048663 32 23 0,000 0,14205857 0,17805707 ! embryonic pattern specification GO:0009880 31 23 0,000 0,14205857 0,17796009 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,14205857 0,17786321 ! vesicle targeting GO:0006903 32 23 0,000 0,14205857 0,17776644 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,14205857 0,17766978 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,14205857 0,17757322 ! osteoblast differentiation GO:0001649 40 23 0,000 0,14205857 0,17747676 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,14205857 0,17738041 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,14205857 0,17728417 ! interaction with host GO:0051701 37 23 0,000 0,14205857 0,17718802 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,14205857 0,17709199 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,14205857 0,17699605 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,14205857 0,17690023 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,14205857 0,1768045 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,14205857 0,17670888 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,14205857 0,17661336 ! cell fate determination GO:0001709 45 23 0,000 0,14205857 0,17651795 ! pentose metabolic process GO:0019321 31 23 0,000 0,14205857 0,17642263 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,14205857 0,17632742 ! spermatid development GO:0007286 33 23 0,000 0,14205857 0,17623232 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,14205857 0,17613731 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,14205857 0,17604241 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,14205857 0,17594761 ! telomere organization GO:0032200 32 23 0,000 0,14205857 0,17585292 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,14205857 0,17575832 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,14205857 0,17566383 ! regulation of amine transport GO:0051952 38 23 0,000 0,14205857 0,17556943 ! liver development GO:0001889 40 23 0,000 0,14205857 0,17547514 ! regulation of translation GO:0006417 151 100 1,000 0,14251151 0,17594014 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,14251151 0,17584575 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,14251151 0,17575146 ! protein localization in organelle GO:0033365 161 100 1,000 0,14251151 0,17565728 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,14775885 0,18202751 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,14775885 0,18193007 ! initiation of viral infection GO:0019059 42 24 0,000 0,14775885 0,18183273 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,14775885 0,18173549 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,14775885 0,18163836 ! superoxide metabolic process GO:0006801 32 24 0,000 0,14775885 0,18154133 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,14775885 0,1814444 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,14775885 0,18134758 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,14775885 0,18125086 ! fat cell differentiation GO:0045444 37 24 0,000 0,14775885 0,18115424 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,14775885 0,18105773 ! vacuole organization GO:0007033 39 24 0,000 0,14775885 0,18096132 ! receptor metabolic process GO:0043112 37 24 0,000 0,14775885 0,18086502 ! neural crest cell development GO:0014032 39 24 0,000 0,14775885 0,18076881 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,14775885 0,18067271 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,14775885 0,18057671 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,14775885 0,18048081 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,14775885 0,18038501 ! glutathione metabolic process GO:0006749 29 24 0,000 0,14775885 0,18028932 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,14775885 0,18019372 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,15342159 0,18700034 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,15342159 0,1869013 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,15342159 0,18680235 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,15342159 0,18670352 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,15342159 0,18660478 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,15342159 0,18650616 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,15342159 0,18640763 ! peptide transport GO:0015833 43 25 0,000 0,15342159 0,18630921 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,15342159 0,1862109 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,15342159 0,18611268 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,15342159 0,18601457 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,15342159 0,18591657 ! detection of light stimulus GO:0009583 30 25 0,000 0,15342159 0,18581867 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,15342159 0,18572087 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,15342159 0,18562317 ! leukocyte proliferation GO:0070661 39 25 0,000 0,15342159 0,18552558 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,15904701 0,19222708 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,15904701 0,19212612 ! translational initiation GO:0006413 43 26 0,000 0,15904701 0,19202527 ! circadian rhythm GO:0007623 42 26 0,000 0,15904701 0,19192452 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,15904701 0,19182388 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,15904701 0,19172334 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,15904701 0,19162291 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,15904701 0,19152258 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,15904701 0,19142236 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,15904701 0,19132224 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,15904701 0,19122223 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,16463538 0,19783771 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,16463538 0,1977344 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,16463538 0,1976312 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,16463538 0,1975281 ! membrane docking GO:0022406 39 27 0,000 0,16463538 0,19742512 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,16463538 0,19732224 ! catechol metabolic process GO:0009712 43 27 0,000 0,16463538 0,19721947 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,16463538 0,1971168 ! acute-phase response GO:0006953 42 27 0,000 0,16463538 0,19701424 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,16463538 0,19691179 ! myofibril assembly GO:0030239 36 27 0,000 0,16463538 0,19680945 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,16463538 0,19670721 ! natural killer cell activation GO:0030101 35 27 0,000 0,16463538 0,19660508 ! lipid oxidation GO:0034440 38 27 0,000 0,16463538 0,19650305 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,16463538 0,19640113 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,16463538 0,19629931 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,16463538 0,1961976 ! gene silencing GO:0016458 41 27 0,000 0,16463538 0,196096 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,17018693 0,20260349 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,17018693 0,20249868 ! phenol metabolic process GO:0018958 44 28 0,000 0,17018693 0,20239397 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,17018693 0,20228937 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,17018693 0,20218489 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,17018693 0,20208051 ! cell junction assembly GO:0034329 56 28 0,000 0,17018693 0,20197623 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,17018693 0,20187207 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,17018693 0,20176801 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,17018693 0,20166406 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,17018693 0,20156022 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,17018693 0,20145648 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,17018693 0,20135285 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,17018693 0,20124933 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,17018693 0,20114591 ! mesoderm formation GO:0001707 46 28 0,000 0,17018693 0,2010426 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,17018693 0,20093939 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,17018693 0,2008363 ! BMP signaling pathway GO:0030509 40 28 0,000 0,17018693 0,2007333 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,17018693 0,20063042 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,17018693 0,20052763 ! neural tube formation GO:0001841 41 28 0,000 0,17018693 0,20042496 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,17018693 0,20032239 ! placenta development GO:0001890 37 28 0,000 0,17018693 0,20021992 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,1757019 0,20660244 ! regulation of innate immune response GO:0045088 38 29 0,000 0,1757019 0,20649687 ! ovulation cycle process GO:0022602 41 29 0,000 0,1757019 0,20639141 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,1757019 0,20628605 ! protein targeting to membrane GO:0006612 53 29 0,000 0,1757019 0,2061808 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,1757019 0,20607566 ! mismatch repair GO:0006298 34 29 0,000 0,1757019 0,20597063 ! muscle cell development GO:0055001 38 29 0,000 0,1757019 0,2058657 ! formation of primary germ layer GO:0001704 48 29 0,000 0,1757019 0,20576088 ! telencephalon development GO:0021537 52 29 0,000 0,1757019 0,20565617 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,1757019 0,20555156 ! eye morphogenesis GO:0048592 51 29 0,000 0,1757019 0,20544706 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,1757019 0,20534267 ! tissue homeostasis GO:0001894 42 29 0,000 0,1757019 0,20523838 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,18118054 0,21153057 ! collagen metabolic process GO:0032963 40 30 0,000 0,18118054 0,21142325 ! organic anion transport GO:0015711 51 30 0,000 0,18118054 0,21131604 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,18118054 0,21120894 ! spliceosome assembly GO:0000245 49 30 0,000 0,18118054 0,21110194 ! spindle organization GO:0007051 37 30 0,000 0,18118054 0,21099505 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,18118054 0,21088827 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,18118054 0,2107816 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,18118054 0,21067504 ! ceramide metabolic process GO:0006672 43 30 0,000 0,18118054 0,21056859 ! ovulation cycle GO:0042698 43 30 0,000 0,18118054 0,21046224 ! hindbrain development GO:0030902 45 30 0,000 0,18118054 0,210356 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,18118054 0,21024986 ! adult locomotory behavior GO:0008344 47 30 0,000 0,18118054 0,21014384 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,18118054 0,21003792 ! response to heat GO:0009408 41 30 0,000 0,18118054 0,20993211 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,18118054 0,2098264 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,18118054 0,2097208 ! glial cell differentiation GO:0010001 55 31 0,000 0,18662307 0,215912 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,18662307 0,21580345 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,18662307 0,215695 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,18662307 0,21558667 ! odontogenesis GO:0042476 50 31 0,000 0,18662307 0,21547844 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,18662307 0,21537032 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,18662307 0,21526231 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,18662307 0,21515441 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,18662307 0,21504662 ! cell fate specification GO:0001708 37 31 0,000 0,18662307 0,21493893 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,18662307 0,21483136 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,18662307 0,21472389 ! RNA modification GO:0009451 40 31 0,000 0,18662307 0,21461653 ! regulation of muscle development GO:0048634 48 32 0,000 0,19202973 0,22072383 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,19202973 0,22061358 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,19202973 0,22050344 ! meiosis I GO:0007127 52 32 0,000 0,19202973 0,22039341 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,19202973 0,22028348 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,19202973 0,22017367 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,19202973 0,22006397 ! cytokine production GO:0001816 44 32 0,000 0,19202973 0,21995437 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,19202973 0,21984489 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,19202973 0,21973551 ! vesicle localization GO:0051648 47 32 0,000 0,19202973 0,21962625 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,19740077 0,22565694 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,19740077 0,22554484 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,19740077 0,22543285 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,19740077 0,22532097 ! sister chromatid segregation GO:0000819 46 33 0,000 0,19740077 0,22520921 ! cell junction organization GO:0034330 63 33 0,000 0,19740077 0,22509755 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,19740077 0,22498601 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,19740077 0,22487457 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,19740077 0,22476325 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,19740077 0,22465204 ! female gonad development GO:0008585 49 33 0,000 0,19740077 0,22454093 ! positive regulation of cell development GO:0010720 54 33 0,000 0,19740077 0,22442994 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,19740077 0,22431905 ! regulation of proteolysis GO:0030162 50 33 0,000 0,19740077 0,22420828 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,19740077 0,22409761 ! cytokinesis GO:0000910 52 33 0,000 0,19740077 0,22398706 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,19740077 0,22387661 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,2027364 0,22981455 ! mRNA catabolic process GO:0006402 48 34 0,000 0,2027364 0,22970134 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,2027364 0,22958825 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,2027364 0,22947526 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,2027364 0,22936238 ! feeding behavior GO:0007631 45 34 0,000 0,2027364 0,22924962 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,2027364 0,22913697 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,2027364 0,22902442 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,2027364 0,22891199 ! polyol metabolic process GO:0019751 44 34 0,000 0,2027364 0,22879967 ! aerobic respiration GO:0009060 47 34 0,000 0,2027364 0,22868746 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,2027364 0,22857536 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,2027364 0,22846336 ! embryonic organ development GO:0048568 45 34 0,000 0,2027364 0,22835148 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,2027364 0,22823971 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,20803687 0,23409237 ! Notch signaling pathway GO:0007219 56 35 0,000 0,20803687 0,2339779 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,20803687 0,23386354 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,20803687 0,23374929 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,20803687 0,23363516 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,20803687 0,23352113 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,20803687 0,23340722 ! pigment metabolic process GO:0042440 61 35 0,000 0,20803687 0,23329342 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,2133024 0,23908164 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,2133024 0,23896519 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,2133024 0,23884884 ! tissue remodeling GO:0048771 62 36 0,000 0,2133024 0,23873262 ! neural tube development GO:0021915 50 36 0,000 0,2133024 0,2386165 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,2133024 0,2385005 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,2133024 0,23838461 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,2133024 0,23826883 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,21853322 0,24399341 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,21853322 0,24387502 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,21853322 0,24375675 ! learning GO:0007612 67 37 0,000 0,21853322 0,24363859 ! ion transmembrane transport GO:0034220 56 37 0,000 0,21853322 0,24352055 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,21853322 0,24340262 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,21853322 0,24328481 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,22372956 0,2489492 ! gliogenesis GO:0042063 71 38 0,000 0,22372956 0,24882882 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,22372956 0,24870855 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,22372956 0,2485884 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,22372956 0,24846837 ! phagocytosis GO:0006909 60 38 0,000 0,22372956 0,24834845 ! maintenance of location in cell GO:0051651 69 38 0,000 0,22372956 0,24822865 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,22889165 0,25383355 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,22889165 0,25371122 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,22889165 0,25358901 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,22889165 0,25346692 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,22889165 0,25334494 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,22889165 0,25322308 ! chromatin remodeling GO:0006338 68 39 0,000 0,22889165 0,25310134 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,22889165 0,25297972 ! JNK cascade GO:0007254 54 39 0,000 0,22889165 0,25285821 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,2340197 0,25839909 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,2340197 0,2582751 ! regulation of tube size GO:0035150 60 40 0,000 0,2340197 0,25815122 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,2340197 0,25802747 ! peptide metabolic process GO:0006518 56 40 0,000 0,2340197 0,25790383 ! inner ear development GO:0048839 57 40 0,000 0,2340197 0,25778032 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,2340197 0,25765692 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,2340197 0,25753364 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,2340197 0,25741047 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,23911394 0,26288817 ! glucose transport GO:0015758 52 41 0,000 0,23911394 0,26276257 ! endosome transport GO:0016197 71 41 0,000 0,23911394 0,26263708 ! striated muscle contraction GO:0006941 62 41 0,000 0,23911394 0,26251172 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,23911394 0,26238648 ! biopolymer methylation GO:0043414 62 41 0,000 0,23911394 0,26226135 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,24417458 0,26768424 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,24417458 0,26755672 ! hexose transport GO:0008645 54 42 0,000 0,24417458 0,26742931 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,24417458 0,26730202 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,24417458 0,26717485 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,24417458 0,26704781 ! excretion GO:0007588 63 42 0,000 0,24417458 0,26692089 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,24417458 0,26679408 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,24417458 0,2666674 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,24417458 0,26654084 ! regulation of cell shape GO:0008360 78 42 0,000 0,24417458 0,2664144 ! leukocyte migration GO:0050900 60 43 0,000 0,24920186 0,27177064 ! neuromuscular process GO:0050905 79 43 0,000 0,24920186 0,27164184 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,24920186 0,27151316 ! tRNA processing GO:0008033 49 43 0,000 0,24920186 0,27138461 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,24920186 0,27125617 ! vesicle organization GO:0016050 79 43 0,000 0,24920186 0,27112786 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,24920186 0,27099966 ! methylation GO:0032259 64 43 0,000 0,24920186 0,27087159 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,25419599 0,27616948 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,25419599 0,27603908 ! regulation of ion transport GO:0043269 57 44 0,000 0,25419599 0,27590882 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,25419599 0,27577867 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,25419599 0,27564865 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,25419599 0,27551875 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,25419599 0,27538897 ! RNA catabolic process GO:0006401 64 45 0,000 0,25915718 0,2806316 ! positive regulation of defense response GO:0031349 59 45 0,000 0,25915718 0,28049954 ! regulation of translational initiation GO:0006446 64 45 0,000 0,25915718 0,2803676 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,25915718 0,28023579 ! cell recognition GO:0008037 58 45 0,000 0,25915718 0,2801041 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,26408566 0,28529686 ! cell redox homeostasis GO:0045454 63 46 0,000 0,26408566 0,28516291 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,26408566 0,2850291 ! regulation of ossification GO:0030278 71 46 0,000 0,26408566 0,28489541 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,26408566 0,28476184 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,26898162 0,28990521 ! viral infectious cycle GO:0019058 71 47 0,000 0,26898162 0,28976943 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,26898162 0,28963377 ! endocrine system development GO:0035270 83 47 0,000 0,26898162 0,28949824 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,26898162 0,28936283 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,26898162 0,28922755 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,26898162 0,2890924 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,26898162 0,28895737 ! chloride transport GO:0006821 67 48 0,000 0,27384529 0,2940449 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,27384529 0,29390769 ! response to temperature stimulus GO:0009266 62 48 0,000 0,27384529 0,2937706 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,27384529 0,29363365 ! gastrulation GO:0007369 73 48 0,000 0,27384529 0,29349682 ! heart morphogenesis GO:0003007 65 48 0,000 0,27384529 0,29336012 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,27384529 0,29322355 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,27384529 0,2930871 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,27384529 0,29295078 ! regulation of endocytosis GO:0030100 63 48 0,000 0,27384529 0,29281459 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,27384529 0,29267852 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,27867688 0,29770406 ! sensory perception of smell GO:0007608 61 49 0,000 0,27867688 0,29756585 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,27867688 0,29742776 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,27867688 0,29728981 ! RNA elongation GO:0006354 62 49 0,000 0,27867688 0,29715199 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,27867688 0,29701429 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,27867688 0,29687672 ! cartilage development GO:0051216 70 49 0,000 0,27867688 0,29673927 ! maintenance of location GO:0051235 84 49 0,000 0,27867688 0,29660196 ! regulation of actin filament length GO:0030832 72 50 0,000 0,2834766 0,30157085 ! membrane fusion GO:0006944 80 50 0,000 0,2834766 0,30143143 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,2834766 0,30129214 ! proton transport GO:0015992 75 50 0,000 0,2834766 0,30115297 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,2834766 0,30101394 ! positive regulation of secretion GO:0051047 71 51 0,000 0,28824466 0,30593572 ! hydrogen transport GO:0006818 77 51 0,000 0,28824466 0,30579461 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,28824466 0,30565362 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,28824466 0,30551277 ! adult behavior GO:0030534 80 51 0,000 0,28824466 0,30537204 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,28824466 0,30523145 ! transition metal ion transport GO:0000041 74 52 0,000 0,29298125 0,31010441 ! regulation of cellular component size GO:0032535 74 52 0,000 0,29298125 0,30996177 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,29298125 0,30981926 ! establishment of organelle localization GO:0051656 85 52 0,000 0,29298125 0,30967688 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,2976866 0,31450582 ! single fertilization GO:0007338 59 53 0,000 0,2976866 0,31436142 ! amino acid transport GO:0006865 84 54 0,000 0,3023609 0,31915102 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,3023609 0,31900462 ! regulation of mitosis GO:0007088 84 54 0,000 0,3023609 0,31885835 GO:0051783|regulation of nuclear division, ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,3023609 0,31871222 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,3023609 0,31856622 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,3023609 0,31842036 ! mesoderm development GO:0007498 76 55 0,000 0,30700435 0,32316248 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,30700435 0,32301464 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,30700435 0,32286695 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,31161717 0,32756832 ! carbohydrate transport GO:0008643 74 57 0,000 0,31619954 0,33223341 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,31619954 0,33208171 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,31619954 0,33193014 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,31619954 0,33177871 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,31619954 0,33162742 ! secondary metabolic process GO:0019748 84 57 0,000 0,31619954 0,33147627 ! viral reproductive process GO:0022415 87 58 0,000 0,32075167 0,33609514 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,32075167 0,33594209 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,32075167 0,33578918 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,32527375 0,34036835 ! activation of MAPK activity GO:0000187 84 59 0,000 0,32527375 0,34021356 ! actin filament organization GO:0007015 95 59 0,000 0,32527375 0,34005892 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,32527375 0,33990442 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,32527375 0,33975006 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,32976599 0,34428587 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,32976599 0,34412966 GO:0035113|embryonic appendage morphogenesis, ! regulation of heart contraction GO:0008016 91 60 0,000 0,32976599 0,34397359 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,32976599 0,34381767 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,33422857 0,34831251 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,33422857 0,34815476 ! extracellular matrix organization GO:0030198 103 61 0,000 0,33422857 0,34799716 ! amine catabolic process GO:0009310 90 62 0,000 0,3386617 0,35245335 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,3386617 0,35229394 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,3386617 0,35213468 ! organelle localization GO:0051640 96 62 0,000 0,3386617 0,35197556 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,34306556 0,3563915 ! viral reproduction GO:0016032 92 63 0,000 0,34306556 0,3562306 ! appendage morphogenesis GO:0035107 93 64 0,000 0,34744034 0,36061047 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,34744034 0,36044781 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,34744034 0,3602853 ! adaptive immune response GO:0002250 94 64 0,000 0,34744034 0,36012293 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 94 65 0,000 0,35178625 0,36446323 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 0,000 0,35178625 0,36429913 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,35178625 0,36413518 ! activation of immune response GO:0002253 83 65 0,000 0,35178625 0,36397138 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,35610345 0,36827246 ! antigen processing and presentation GO:0019882 96 66 0,000 0,35610345 0,36810694 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,36039215 0,37237285 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,36039215 0,37220564 ! acute inflammatory response GO:0002526 92 68 0,000 0,36465253 0,37643664 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,36465253 0,37626776 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,36465253 0,37609903 ! rhythmic process GO:0048511 105 68 0,000 0,36465253 0,37593045 ! inorganic anion transport GO:0015698 93 68 0,000 0,36465253 0,37576202 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,36888478 0,37995297 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,36888478 0,3797829 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,37308907 0,38393954 ! humoral immune response GO:0006959 86 70 0,000 0,37308907 0,38376783 ! amine transport GO:0015837 101 70 0,000 0,37308907 0,38359627 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,37308907 0,38342487 ! regulation of catabolic process GO:0009894 106 70 0,000 0,37308907 0,38325362 ! muscle cell differentiation GO:0042692 104 71 0,000 0,3772656 0,38737093 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,3772656 0,38719807 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,3772656 0,38702537 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,38141454 0,39110719 ! regulation of blood pressure GO:0008217 107 73 0,000 0,38553607 0,39515729 ! tube morphogenesis GO:0035239 118 73 0,000 0,38553607 0,39498128 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,38553607 0,39480542 ! digestion GO:0007586 97 74 0,000 0,38963038 0,39882059 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,38963038 0,39864318 ! response to nutrient GO:0007584 104 75 0,000 0,39369764 0,40262542 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,39369764 0,40244648 ! amine biosynthetic process GO:0009309 97 76 0,000 0,39773803 0,40639603 ! response to unfolded protein GO:0006986 99 76 0,000 0,39773803 0,40621557 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,39773803 0,40603527 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,40175173 0,40995074 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,40175173 0,40976895 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,40175173 0,40958731 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,40175173 0,40940584 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,4057389 0,41328586 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,4057389 0,41310291 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,4057389 0,41292012 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,40969973 0,41676665 ! cellular respiration GO:0045333 107 79 0,000 0,40969973 0,4165824 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,40969973 0,41639831 ! regulation of lyase activity GO:0051339 133 79 0,000 0,40969973 0,41621439 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,40969973 0,41603063 ! chromatin assembly GO:0031497 102 80 0,000 0,41363439 0,41984073 GO:0006334|nucleosome assembly, ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,41754304 0,42362109 ! mRNA transport GO:0051028 121 81 0,000 0,41754304 0,4234343 ! response to protein stimulus GO:0051789 111 81 0,000 0,41754304 0,42324769 ! regulation of neurological system process GO:0031644 122 81 0,000 0,41754304 0,42306123 ! vitamin metabolic process GO:0006766 103 81 0,000 0,41754304 0,42287495 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,42528303 0,43052419 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of defense response GO:0031347 117 84 0,000 0,4291147 0,43421197 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,4291147 0,43402102 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,43292103 0,43767841 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,43670221 0,44130716 ! nucleosome organization GO:0034728 114 87 0,000 0,4404584 0,44490747 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,4404584 0,44471216 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,4404584 0,44451703 ! female pregnancy GO:0007565 130 87 0,000 0,4404584 0,44432207 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,44418974 0,4478897 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,44418974 0,44769343 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,44418974 0,44749733 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,44789642 0,45103405 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,44789642 0,45083666 ! hormone metabolic process GO:0042445 121 90 0,000 0,4515786 0,45434417 ! ATP metabolic process GO:0046034 137 91 0,000 0,45523642 0,45782412 ! response to virus GO:0009615 122 91 0,000 0,45523642 0,45762402 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,45887006 0,4610752 ! positive regulation of immune response GO:0050778 121 92 0,000 0,45887006 0,46087386 ! DNA recombination GO:0006310 146 92 0,000 0,45887006 0,46067269 ! sulfur metabolic process GO:0006790 118 92 0,000 0,45887006 0,4604717 ! electron transport chain GO:0022900 123 94 0,000 0,4660654 0,46748819 ! response to oxidative stress GO:0006979 141 94 0,000 0,4660654 0,4672844 ! carboxylic acid transport GO:0046942 147 95 0,000 0,46962742 0,47065057 GO:0015849|organic acid transport, ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,47668094 0,47751139 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,48364145 0,48427311 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,4870872 0,48751113 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,4870872 0,48729907 ! divalent metal ion transport GO:0070838 171 100 0,000 0,4870872 0,4870872