pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6541-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 224 98 12,000 1,081E-13 2,64E-10 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 9,000 4,358E-13 5,324E-10 ! protein sumoylation GO:0016925 17 10 5,000 1,609E-11 1,311E-08 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 8,000 1,414E-10 8,633E-08 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 4,000 2,515E-10 1,229E-07 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 4,000 2,97E-09 1,209E-06 ! negative regulation of phosphorylation GO:0042326 52 24 5,000 9,546E-09 3,332E-06 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 5,000 1,615E-08 4,932E-06 GO:0045936|negative regulation of phosphate metabolic process, ! induction of apoptosis by intracellular signals GO:0008629 95 45 6,000 1,85E-08 5,023E-06 ! positive regulation of cell migration GO:0030335 137 58 6,000 1,14E-07 2,784E-05 ! negative regulation of DNA binding GO:0043392 67 36 5,000 1,293E-07 2,871E-05 ! negative regulation of binding GO:0051100 71 39 5,000 2,13E-07 4,336E-05 ! positive regulation of cell motion GO:0051272 157 65 6,000 2,537E-07 4,768E-05 ! regulation of protein localization GO:0032880 188 97 7,000 2,823E-07 4,927E-05 ! negative regulation of protein kinase activity GO:0006469 144 69 6,000 3,845E-07 6,262E-05 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 6,000 3,845E-07 5,871E-05 ! negative regulation of kinase activity GO:0033673 145 70 6,000 4,248E-07 6,105E-05 ! negative regulation of transferase activity GO:0051348 155 74 6,000 6,236E-07 8,464E-05 ! negative regulation of transcription regulator activity GO:0090048 57 30 4,000 1,507E-06 1,938E-04 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 3,000 1,77E-06 2,162E-04 ! regulation of DNA binding GO:0051101 167 89 6,000 2,195E-06 2,554E-04 ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 2,000 2,826E-06 3,138E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 2,826E-06 3,001E-04 ! peptidyl-threonine phosphorylation GO:0018107 20 5 2,000 2,826E-06 2,876E-04 ! positive regulation of MAP kinase activity GO:0043406 174 93 6,000 2,952E-06 2,884E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 3,000 4,143E-06 3,893E-04 ! protein amino acid autophosphorylation GO:0046777 157 64 5,000 4,264E-06 3,858E-04 ! positive regulation of protein complex assembly GO:0031334 34 18 3,000 5,299E-06 4,623E-04 ! cell-substrate junction assembly GO:0007044 56 18 3,000 5,299E-06 4,464E-04 ! neural nucleus development GO:0048857 19 6 2,000 5,624E-06 4,579E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 8,303E-06 6,544E-04 ! peptidyl-serine phosphorylation GO:0018105 44 20 3,000 8,303E-06 6,339E-04 ! prostate gland development GO:0030850 14 7 2,000 9,793E-06 7,25E-04 ! peptidyl-threonine modification GO:0018210 26 7 2,000 9,793E-06 7,037E-04 ! regulation of transcription factor activity GO:0051090 137 75 5,000 1,078E-05 7,524E-04 GO:0090046|regulation of transcription regulator activity, ! glutamate signaling pathway GO:0007215 48 22 3,000 1,241E-05 8,419E-04 ! apoptotic nuclear changes GO:0030262 34 22 3,000 1,241E-05 8,192E-04 ! positive regulation of locomotion GO:0040017 44 22 3,000 1,241E-05 7,976E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! peptidyl-serine modification GO:0018209 50 22 3,000 1,241E-05 7,772E-04 ! pigmentation GO:0043473 103 46 4,000 1,33E-05 8,125E-04 ! positive regulation of DNA replication GO:0045740 44 23 3,000 1,494E-05 8,903E-04 ! regulation of chemotaxis GO:0050920 45 23 3,000 1,494E-05 8,691E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 1,559E-05 8,859E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 1,559E-05 8,657E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,559E-05 8,465E-04 ! positive regulation of fibroblast proliferation GO:0048146 48 25 3,000 2,112E-05 1,122E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 3,000 2,112E-05 1,098E-03 ! regulation of behavior GO:0050795 48 25 3,000 2,112E-05 1,075E-03 ! induction of positive chemotaxis GO:0050930 17 9 2,000 2,327E-05 1,16E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 3,000 2,484E-05 1,213E-03 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 2,9E-05 1,389E-03 ! response to UV GO:0009411 120 55 4,000 3,217E-05 1,511E-03 ! gland development GO:0048732 220 91 5,000 3,268E-05 1,506E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 3,309E-05 1,497E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 3,309E-05 1,47E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 3,000 3,366E-05 1,469E-03 ! negative regulation of protein modification process GO:0031400 66 28 3,000 3,366E-05 1,443E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 3,000 3,366E-05 1,418E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 4,527E-05 1,875E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 4,527E-05 1,843E-03 GO:0010829|negative regulation of glucose transport, ! regulation of DNA metabolic process GO:0051052 188 97 5,000 4,687E-05 1,877E-03 ! cell junction assembly GO:0034329 85 31 3,000 5,093E-05 2,007E-03 ! negative regulation of response to stimulus GO:0048585 106 61 4,000 5,327E-05 2,066E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 6,007E-05 2,293E-03 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 6,007E-05 2,258E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 37 12 2,000 6,007E-05 2,223E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 6,007E-05 2,19E-03 GO:0042130|negative regulation of T cell proliferation, ! response to peptide hormone stimulus GO:0043434 129 64 4,000 6,718E-05 2,413E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 3,000 7,391E-05 2,617E-03 ! regulation of synaptic plasticity GO:0048167 78 35 3,000 8,301E-05 2,897E-03 ! negative regulation of protein import into nucleus GO:0042308 33 14 2,000 9,842E-05 3,386E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 9,842E-05 3,339E-03 ! cell junction organization GO:0034330 96 37 3,000 1,036E-04 3,468E-03 ! negative regulation of cell activation GO:0050866 69 37 3,000 1,036E-04 3,421E-03 ! cell cycle checkpoint GO:0000075 145 71 4,000 1,105E-04 3,599E-03 ! positive regulation of DNA metabolic process GO:0051054 77 38 3,000 1,152E-04 3,704E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 1,152E-04 3,656E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 1,224E-04 3,834E-03 ! nucleus organization GO:0006997 73 40 3,000 1,412E-04 4,366E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 2,000 1,499E-04 4,579E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 1,499E-04 4,522E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of intracellular protein transport GO:0033157 86 42 3,000 1,711E-04 5,099E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 1,812E-04 5,333E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 1,812E-04 5,269E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 2,054E-04 5,904E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 2,061E-04 5,854E-03 ! limbic system development GO:0021761 40 18 2,000 2,164E-04 6,075E-03 ! regulation of viral genome replication GO:0045069 30 18 2,000 2,164E-04 6,006E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 2,164E-04 5,939E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 2,243E-04 6,089E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 2,311E-04 6,203E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 2,444E-04 6,49E-03 ! cell growth GO:0016049 90 46 3,000 2,444E-04 6,42E-03 ! memory GO:0007613 34 19 2,000 2,557E-04 6,645E-03 ! cellular pigmentation GO:0033059 37 19 2,000 2,557E-04 6,575E-03 ! negative regulation of transport GO:0051051 164 85 4,000 2,583E-04 6,572E-03 ! regulation of neuron differentiation GO:0045664 187 85 4,000 2,583E-04 6,504E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 2,658E-04 6,625E-03 ! response to alkaloid GO:0043279 38 20 2,000 2,993E-04 7,386E-03 ! estrogen receptor signaling pathway GO:0030520 45 20 2,000 2,993E-04 7,312E-03 ! regulation of glucose import GO:0046324 30 20 2,000 2,993E-04 7,24E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 2,993E-04 7,169E-03 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 3,124E-04 7,411E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 3,475E-04 8,163E-03 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 3,475E-04 8,085E-03 ! negative regulation of intracellular transport GO:0032387 44 21 2,000 3,475E-04 8,009E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 3,475E-04 7,934E-03 ! collagen catabolic process GO:0030574 29 21 2,000 3,475E-04 7,861E-03 ! reciprocal meiotic recombination GO:0007131 44 22 2,000 4,004E-04 8,975E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 4,004E-04 8,893E-03 ! regulation of membrane potential GO:0042391 179 94 4,000 4,119E-04 9,065E-03 ! positive regulation of growth GO:0045927 96 53 3,000 4,23E-04 9,227E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 4,23E-04 9,145E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of muscle development GO:0048636 15 5 1,000 4,296E-04 9,206E-03 GO:0045844|positive regulation of striated muscle development, ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 4,296E-04 9,126E-03 ! hypothalamus development GO:0021854 9 5 1,000 4,296E-04 9,047E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 4,296E-04 8,97E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 4,296E-04 8,894E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 4,296E-04 8,819E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 4,296E-04 8,746E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 4,296E-04 8,674E-03 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 1,000 4,296E-04 8,602E-03 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! sister chromatid cohesion GO:0007062 15 5 1,000 4,296E-04 8,533E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 4,296E-04 8,464E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,296E-04 8,396E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 4,296E-04 8,329E-03 ! decidualization GO:0046697 11 5 1,000 4,296E-04 8,264E-03 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 1,000 4,296E-04 8,199E-03 ! B cell homeostasis GO:0001782 13 5 1,000 4,296E-04 8,136E-03 ! regulation of mitochondrial depolarization GO:0051900 14 5 1,000 4,296E-04 8,073E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 4,296E-04 8,011E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 4,296E-04 7,951E-03 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 4,296E-04 7,891E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 4,296E-04 7,832E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 4,296E-04 7,774E-03 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 4,296E-04 7,717E-03 GO:0048103|somatic stem cell division, ! regulation of cell-matrix adhesion GO:0001952 81 23 2,000 4,582E-04 8,171E-03 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 2,000 4,582E-04 8,112E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 4,582E-04 8,054E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 5,212E-04 9,094E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 5,212E-04 9,03E-03 ! regulation of viral reproduction GO:0050792 41 24 2,000 5,212E-04 8,966E-03 ! pallium development GO:0021543 56 24 2,000 5,212E-04 8,903E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 5,224E-04 8,863E-03 ! regulation of intracellular transport GO:0032386 108 57 3,000 5,589E-04 9,417E-03 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 6,416E-04 0,0107355 ! regulation of retroviral genome replication GO:0045091 8 6 1,000 6,416E-04 0,01066247 ! negative regulation of platelet activation GO:0010544 9 6 1,000 6,416E-04 0,01059043 GO:0010543|regulation of platelet activation, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 6,416E-04 0,01051935 GO:0045686|negative regulation of glial cell differentiation, ! astrocyte development GO:0014002 16 6 1,000 6,416E-04 0,01044922 ! regulation of dendrite development GO:0050773 16 6 1,000 6,416E-04 0,01038002 ! Schwann cell development GO:0014044 15 6 1,000 6,416E-04 0,01031173 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 6,416E-04 0,01024434 ! maternal placenta development GO:0001893 12 6 1,000 6,416E-04 0,01017782 ! negative regulation of B cell activation GO:0050869 14 6 1,000 6,416E-04 0,01011215 ! cellular anion homeostasis GO:0030002 11 6 1,000 6,416E-04 0,01004733 GO:0055081|anion homeostasis, ! myelination GO:0042552 50 26 2,000 6,63E-04 0,01031617 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 6,63E-04 0,01025088 ! negative regulation of cell development GO:0010721 83 26 2,000 6,63E-04 0,01018641 GO:0050768|negative regulation of neurogenesis, ! multicellular organismal catabolic process GO:0044243 38 27 2,000 7,422E-04 0,01133273 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 7,422E-04 0,01126234 ! regulation of protein complex assembly GO:0043254 132 63 3,000 8,172E-04 0,01232361 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 8,272E-04 0,01239851 ! fat cell differentiation GO:0045444 57 28 2,000 8,272E-04 0,01232291 ! regulation of JUN kinase activity GO:0043506 67 28 2,000 8,272E-04 0,01224822 ! sleep GO:0030431 16 7 1,000 8,943E-04 0,01316125 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 8,943E-04 0,01308244 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 8,943E-04 0,01300457 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 8,943E-04 0,01292762 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 1,000 8,943E-04 0,01285157 GO:0031958|corticosteroid receptor signaling pathway, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 8,943E-04 0,01277642 ! glucocorticoid metabolic process GO:0008211 11 7 1,000 8,943E-04 0,01270213 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 8,943E-04 0,01262871 ! organ growth GO:0035265 15 7 1,000 8,943E-04 0,01255613 ! male sex determination GO:0030238 15 7 1,000 8,943E-04 0,01248438 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 8,943E-04 0,01241345 ! B cell lineage commitment GO:0002326 21 7 1,000 8,943E-04 0,01234332 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 8,943E-04 0,01227397 ! T cell lineage commitment GO:0002360 16 7 1,000 8,943E-04 0,0122054 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 8,943E-04 0,01213759 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 9,182E-04 0,01239334 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 9,736E-04 0,01306882 ! positive regulation of multicellular organism growth GO:0040018 55 30 2,000 1,015E-03 0,01355374 ! regulation of B cell activation GO:0050864 55 30 2,000 1,015E-03 0,01348007 ! negative regulation of cell growth GO:0030308 142 67 3,000 1,03E-03 0,013603 ! chromosome segregation GO:0007059 127 67 3,000 1,03E-03 0,01352986 ! ensheathment of neurons GO:0007272 64 31 2,000 1,119E-03 0,01461365 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 1,119E-03 0,01453592 ! negative regulation of cell size GO:0045792 144 69 3,000 1,15E-03 0,01486413 ! lung development GO:0030324 165 69 3,000 1,15E-03 0,0147859 ! urogenital system development GO:0001655 149 69 3,000 1,15E-03 0,01470848 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,187E-03 0,01510586 ! pigment granule organization GO:0048753 17 8 1,000 1,187E-03 0,01502759 ! astrocyte differentiation GO:0048708 19 8 1,000 1,187E-03 0,01495013 ! ER overload response GO:0006983 13 8 1,000 1,187E-03 0,01487346 ! regulation of pigmentation during development GO:0048070 25 8 1,000 1,187E-03 0,01479758 ! melanin metabolic process GO:0006582 17 8 1,000 1,187E-03 0,01472246 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,187E-03 0,01464811 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,187E-03 0,0145745 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,187E-03 0,01450163 ! Schwann cell differentiation GO:0014037 21 8 1,000 1,187E-03 0,01442948 ! response to UV-B GO:0010224 17 8 1,000 1,187E-03 0,01435805 ! DNA topological change GO:0006265 12 8 1,000 1,187E-03 0,01428732 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,187E-03 0,01421728 ! hormone catabolic process GO:0042447 17 8 1,000 1,187E-03 0,01414793 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 1,187E-03 0,01407925 ! collagen metabolic process GO:0032963 49 32 2,000 1,228E-03 0,0144967 ! regulation of protein import into nucleus GO:0042306 69 32 2,000 1,228E-03 0,014427 ! peripheral nervous system development GO:0007422 68 32 2,000 1,228E-03 0,01435797 ! hindbrain development GO:0030902 65 32 2,000 1,228E-03 0,0142896 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 1,279E-03 0,01481115 ! leukocyte chemotaxis GO:0030595 55 33 2,000 1,345E-03 0,01549473 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 74 33 2,000 1,345E-03 0,01542199 ! respiratory tube development GO:0030323 171 72 3,000 1,348E-03 0,01538324 ! actin filament organization GO:0007015 167 72 3,000 1,348E-03 0,01531169 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 1,492E-03 0,01687137 ! respiratory system development GO:0060541 175 74 3,000 1,492E-03 0,01679362 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,52E-03 0,01703094 ! cell proliferation in forebrain GO:0021846 18 9 1,000 1,52E-03 0,01695317 ! regulation of glycolysis GO:0006110 20 9 1,000 1,52E-03 0,01687611 ! cerebral cortex cell migration GO:0021795 18 9 1,000 1,52E-03 0,01679975 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 1,000 1,52E-03 0,01672407 ! microtubule bundle formation GO:0001578 22 9 1,000 1,52E-03 0,01664908 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,52E-03 0,01657475 ! T cell selection GO:0045058 27 9 1,000 1,52E-03 0,01650108 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,52E-03 0,01642807 ! response to amine stimulus GO:0014075 13 9 1,000 1,52E-03 0,0163557 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 1,52E-03 0,01628397 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 1,52E-03 0,01621286 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,52E-03 0,01614237 ! reproductive structure development GO:0048608 131 75 3,000 1,568E-03 0,01657919 ! phosphoinositide-mediated signaling GO:0048015 141 75 3,000 1,568E-03 0,01650772 ! DNA damage checkpoint GO:0000077 78 35 2,000 1,597E-03 0,01674854 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 2,000 1,597E-03 0,01667697 ! telencephalon development GO:0021537 81 35 2,000 1,597E-03 0,016606 ! learning or memory GO:0007611 161 76 3,000 1,646E-03 0,0170417 ! regulation of developmental growth GO:0048638 16 10 1,000 1,891E-03 0,01949672 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 1,000 1,891E-03 0,0194148 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,891E-03 0,01933357 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 1,891E-03 0,01925301 ! B cell proliferation GO:0042100 19 10 1,000 1,891E-03 0,01917312 ! epithelial cell development GO:0002064 21 10 1,000 1,891E-03 0,01909389 ! motor axon guidance GO:0008045 22 10 1,000 1,891E-03 0,01901532 ! protein heterooligomerization GO:0051291 17 10 1,000 1,891E-03 0,01893739 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,891E-03 0,01886009 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 1,891E-03 0,01878342 ! DNA ligation GO:0006266 18 10 1,000 1,891E-03 0,01870738 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 1,891E-03 0,01863195 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,891E-03 0,01855712 GO:0043470|regulation of carbohydrate catabolic process, ! blastocyst formation GO:0001825 18 10 1,000 1,891E-03 0,01848289 ! response to nicotine GO:0035094 20 10 1,000 1,891E-03 0,01840925 ! regulation of synaptic transmission GO:0050804 159 79 3,000 1,898E-03 0,01840476 ! meiosis I GO:0007127 74 38 2,000 2,029E-03 0,01959346 ! DNA integrity checkpoint GO:0031570 82 38 2,000 2,029E-03 0,01951632 ! regulation of protein stability GO:0031647 77 38 2,000 2,029E-03 0,01943978 ! meiosis GO:0007126 143 81 3,000 2,081E-03 0,01985653 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 3,000 2,081E-03 0,01977927 ! meiotic cell cycle GO:0051321 144 82 3,000 2,176E-03 0,02060699 ! regulation of neuron projection development GO:0010975 102 39 2,000 2,188E-03 0,02063412 ! carbohydrate homeostasis GO:0033500 59 39 2,000 2,188E-03 0,02055476 GO:0042593|glucose homeostasis, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 2,000 2,188E-03 0,020476 ! response to drug GO:0042493 149 83 3,000 2,275E-03 0,02121075 ! response to oxygen levels GO:0070482 183 83 3,000 2,275E-03 0,0211301 ! telencephalon cell migration GO:0022029 23 11 1,000 2,302E-03 0,02129914 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,302E-03 0,02121876 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 2,302E-03 0,02113899 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,302E-03 0,02105982 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 2,302E-03 0,02098124 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 2,302E-03 0,02090324 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,302E-03 0,02082582 ! substrate-bound cell migration GO:0006929 14 11 1,000 2,302E-03 0,02074897 ! behavioral fear response GO:0001662 27 11 1,000 2,302E-03 0,02067269 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 1,000 2,302E-03 0,02059697 ! alpha-beta T cell activation GO:0046631 26 11 1,000 2,302E-03 0,0205218 ! DNA methylation GO:0006306 19 11 1,000 2,302E-03 0,02044717 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 25 11 1,000 2,302E-03 0,02037309 ! apical protein localization GO:0045176 18 11 1,000 2,302E-03 0,02029954 ! thymus development GO:0048538 29 11 1,000 2,302E-03 0,02022652 ! oocyte development GO:0048599 20 11 1,000 2,302E-03 0,02015402 ! regulation of embryonic development GO:0045995 35 11 1,000 2,302E-03 0,02008204 ! learning GO:0007612 82 40 2,000 2,353E-03 0,02046116 ! regulation of action potential in neuron GO:0019228 80 40 2,000 2,353E-03 0,0203886 ! negative regulation of growth GO:0045926 168 85 3,000 2,481E-03 0,02141608 ! regulation of transmission of nerve impulse GO:0051969 167 85 3,000 2,481E-03 0,02134067 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 2,481E-03 0,02126579 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 2,527E-03 0,0215856 ! mitochondrion organization GO:0007005 159 87 3,000 2,699E-03 0,02297831 ! regulation of protein transport GO:0051223 165 87 3,000 2,699E-03 0,02289852 GO:0070201|regulation of establishment of protein localization, ! regulation of T cell differentiation GO:0045580 78 42 2,000 2,708E-03 0,02289343 ! dorsal/ventral pattern formation GO:0009953 75 42 2,000 2,708E-03 0,02281449 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 2,75E-03 0,02308666 ! virus-host interaction GO:0019048 30 12 1,000 2,75E-03 0,02300759 ! hippocampus development GO:0021766 29 12 1,000 2,75E-03 0,02292907 ! mitotic spindle organization GO:0007052 23 12 1,000 2,75E-03 0,02285108 ! forebrain cell migration GO:0021885 24 12 1,000 2,75E-03 0,02277362 ! cranial nerve development GO:0021545 23 12 1,000 2,75E-03 0,02269668 ! histone acetylation GO:0016573 27 12 1,000 2,75E-03 0,02262026 ! autonomic nervous system development GO:0048483 24 12 1,000 2,75E-03 0,02254435 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,75E-03 0,02246895 ! T cell homeostasis GO:0043029 28 12 1,000 2,75E-03 0,02239406 ! oocyte differentiation GO:0009994 21 12 1,000 2,75E-03 0,02231966 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 2,75E-03 0,02224575 ! embryonic placenta development GO:0001892 21 12 1,000 2,75E-03 0,02217233 ! localization within membrane GO:0051668 26 12 1,000 2,75E-03 0,0220994 ! development of primary male sexual characteristics GO:0046546 80 43 2,000 2,897E-03 0,02320663 ! regulation of T cell proliferation GO:0042129 80 43 2,000 2,897E-03 0,02313079 ! regulation of neurological system process GO:0031644 175 89 3,000 2,931E-03 0,02332307 ! positive regulation of protein modification process GO:0031401 156 90 3,000 3,052E-03 0,02420433 ! response to reactive oxygen species GO:0000302 75 44 2,000 3,094E-03 0,02446344 ! negative regulation of cell projection organization GO:0031345 42 13 1,000 3,236E-03 0,02550063 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 3,236E-03 0,02541864 ! negative regulation of lipid metabolic process GO:0045833 20 13 1,000 3,236E-03 0,02533717 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 3,236E-03 0,02525622 ! indolalkylamine metabolic process GO:0006586 19 13 1,000 3,236E-03 0,02517578 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! asymmetric protein localization GO:0008105 24 13 1,000 3,236E-03 0,02509586 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 3,236E-03 0,02501644 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 3,236E-03 0,02493753 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,236E-03 0,02485911 ! gland morphogenesis GO:0022612 31 13 1,000 3,236E-03 0,02478118 ! spleen development GO:0048536 24 13 1,000 3,236E-03 0,02470374 ! digestive tract morphogenesis GO:0048546 31 13 1,000 3,236E-03 0,02462678 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 3,236E-03 0,0245503 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 3,236E-03 0,02447429 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 3,299E-03 0,02487656 ! regulation of cell adhesion GO:0030155 241 92 3,000 3,303E-03 0,02482792 ! regulation of cell morphogenesis GO:0022604 243 93 3,000 3,434E-03 0,02573215 ! glycolysis GO:0006096 71 46 2,000 3,512E-03 0,02624059 ! leukocyte migration GO:0050900 75 46 2,000 3,512E-03 0,02616059 ! negative regulation of cell migration GO:0030336 122 46 2,000 3,512E-03 0,02608108 ! regulation of JNK cascade GO:0046328 104 47 2,000 3,734E-03 0,02764076 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 3,759E-03 0,02774216 ! response to gamma radiation GO:0010332 30 14 1,000 3,759E-03 0,0276586 ! male genitalia development GO:0030539 26 14 1,000 3,759E-03 0,02757554 ! hair follicle morphogenesis GO:0031069 27 14 1,000 3,759E-03 0,02749298 ! fear response GO:0042596 34 14 1,000 3,759E-03 0,02741091 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 3,759E-03 0,02732933 GO:0060675|ureteric bud morphogenesis, ! sex differentiation GO:0007548 171 96 3,000 3,847E-03 0,02789004 ! positive regulation of cell cycle GO:0045787 96 48 2,000 3,963E-03 0,02864667 ! positive regulation of defense response GO:0031349 88 48 2,000 3,963E-03 0,02856216 ! cellular component disassembly GO:0022411 89 48 2,000 3,963E-03 0,02847816 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 2,000 3,963E-03 0,02839464 ! male sex differentiation GO:0046661 93 48 2,000 3,963E-03 0,02831162 ! regulation of inflammatory response GO:0050727 84 48 2,000 3,963E-03 0,02822908 ! forebrain development GO:0030900 210 98 3,000 4,141E-03 0,02940805 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 4,202E-03 0,02975149 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 4,318E-03 0,03048948 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,318E-03 0,03040162 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 4,318E-03 0,03031426 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 1,000 4,318E-03 0,0302274 ! dopamine metabolic process GO:0042417 35 15 1,000 4,318E-03 0,03014103 ! lymphocyte homeostasis GO:0002260 33 15 1,000 4,318E-03 0,03005516 ! actin filament polymerization GO:0030041 27 15 1,000 4,318E-03 0,02996978 ! regulation of action potential GO:0001508 102 50 2,000 4,448E-03 0,03078398 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 4,448E-03 0,03069702 ! activation of caspase activity GO:0006919 95 50 2,000 4,448E-03 0,03061055 ! regulation of cell projection organization GO:0031344 135 51 2,000 4,703E-03 0,03227592 ! negative regulation of immune system process GO:0002683 101 51 2,000 4,703E-03 0,03218551 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,914E-03 0,03353096 ! heterophilic cell adhesion GO:0007157 43 16 1,000 4,914E-03 0,03343756 ! startle response GO:0001964 28 16 1,000 4,914E-03 0,03334468 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 4,914E-03 0,03325231 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! pituitary gland development GO:0021983 30 16 1,000 4,914E-03 0,03316045 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 1,000 4,914E-03 0,0330691 ! DNA replication initiation GO:0006270 28 16 1,000 4,914E-03 0,03297825 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 4,914E-03 0,0328879 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 4,967E-03 0,0331555 ! cartilage development GO:0051216 99 53 2,000 5,24E-03 0,03488013 ! activation of phospholipase C activity GO:0007202 110 54 2,000 5,521E-03 0,03665407 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 2,000 5,521E-03 0,03655473 ! metencephalon development GO:0022037 32 17 1,000 5,545E-03 0,03660977 ! glial cell development GO:0021782 28 17 1,000 5,545E-03 0,03651109 ! regulation of survival gene product expression GO:0045884 38 17 1,000 5,545E-03 0,03641294 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 5,545E-03 0,03631532 GO:0031114|regulation of microtubule depolymerization, ! regulation of protein binding GO:0043393 33 17 1,000 5,545E-03 0,03621822 ! genitalia development GO:0048806 32 17 1,000 5,545E-03 0,03612164 ! negative regulation of blood coagulation GO:0030195 25 17 1,000 5,545E-03 0,03602557 ! steroid catabolic process GO:0006706 34 17 1,000 5,545E-03 0,03593001 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 5,545E-03 0,03583496 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 5,545E-03 0,03574041 ! positive regulation of phospholipase activity GO:0010518 111 55 2,000 5,812E-03 0,0373636 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 5,812E-03 0,03726553 ! negative regulation of cell motion GO:0051271 142 55 2,000 5,812E-03 0,03716797 ! glucose catabolic process GO:0006007 88 56 2,000 6,111E-03 0,03898067 ! epidermis morphogenesis GO:0048730 43 18 1,000 6,211E-03 0,03951236 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 6,211E-03 0,03940973 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 6,211E-03 0,03930763 ! nerve development GO:0021675 34 18 1,000 6,211E-03 0,03920606 ! defense response to virus GO:0051607 43 18 1,000 6,211E-03 0,03910502 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 6,211E-03 0,03900449 ! positive regulation of caspase activity GO:0043280 108 57 2,000 6,42E-03 0,04021322 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 2,000 6,42E-03 0,04011038 ! aging GO:0007568 112 58 2,000 6,737E-03 0,04198728 ! positive regulation of lipase activity GO:0060193 115 58 2,000 6,737E-03 0,04188044 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 6,911E-03 0,04285354 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 6,911E-03 0,04274505 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 6,911E-03 0,0426371 ! protein amino acid ADP-ribosylation GO:0006471 37 19 1,000 6,911E-03 0,04252971 ! regulation of postsynaptic membrane potential GO:0060078 38 19 1,000 6,911E-03 0,04242285 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 6,911E-03 0,04231652 ! cerebral cortex development GO:0021987 40 19 1,000 6,911E-03 0,04221073 ! pigmentation during development GO:0048066 42 19 1,000 6,911E-03 0,04210547 ! neuromuscular junction development GO:0007528 43 19 1,000 6,911E-03 0,04200073 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 6,911E-03 0,04189651 ! visual learning GO:0008542 38 19 1,000 6,911E-03 0,0417928 ! DNA catabolic process GO:0006308 94 60 2,000 7,4E-03 0,04463765 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,646E-03 0,04600758 ! protein amino acid acetylation GO:0006473 41 20 1,000 7,646E-03 0,04589454 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 7,646E-03 0,04578205 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 7,646E-03 0,04567011 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to unfolded protein GO:0034620 35 20 1,000 7,646E-03 0,04555872 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 1,000 7,646E-03 0,04544787 ! negative regulation of coagulation GO:0050819 30 20 1,000 7,646E-03 0,04533756 ! cytokine-mediated signaling pathway GO:0019221 112 61 2,000 7,745E-03 0,0458158 ! regulation of heart contraction GO:0008016 123 61 2,000 7,745E-03 0,04570514 ! viral reproductive process GO:0022415 132 62 2,000 8,1E-03 0,04768313 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 8,1E-03 0,04756851 ! regulation of homeostatic process GO:0032844 148 62 2,000 8,1E-03 0,04745444 ! lipid phosphorylation GO:0046834 43 21 1,000 8,414E-03 0,04917687 ! ovarian follicle development GO:0001541 39 21 1,000 8,414E-03 0,0490595 ! diencephalon development GO:0021536 36 21 1,000 8,414E-03 0,04894269 ! skeletal system morphogenesis GO:0048705 118 63 2,000 8,464E-03 0,04911663 ! actin polymerization or depolymerization GO:0008154 52 22 1,000 9,216E-03 0,05335 ! ureteric bud development GO:0001657 50 22 1,000 9,216E-03 0,05322388 ! cell aging GO:0007569 48 22 1,000 9,216E-03 0,05309835 ! renal system process GO:0003014 42 22 1,000 9,216E-03 0,05297342 ! G1 phase GO:0051318 44 22 1,000 9,216E-03 0,05284906 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 9,216E-03 0,0527253 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 9,216E-03 0,05260211 ! positive regulation of B cell activation GO:0050871 42 22 1,000 9,216E-03 0,05247949 ! response to cytokine stimulus GO:0034097 69 22 1,000 9,216E-03 0,05235745 ! activation of JUN kinase activity GO:0007257 47 22 1,000 9,216E-03 0,05223597 ! gut development GO:0048565 44 22 1,000 9,216E-03 0,05211505 ! multicellular organism reproduction GO:0032504 123 65 2,000 9,221E-03 0,0520252 GO:0048609|reproductive process in a multicellular organism, ! ear development GO:0043583 114 66 2,000 9,614E-03 0,05411604 ! activation of MAPK activity GO:0000187 124 67 2,000 0,01001609 0,05625131 ! viral genome replication GO:0019079 44 23 1,000 0,01004963 0,0563102 ! regeneration GO:0031099 42 23 1,000 0,01004963 0,05618134 ! axis specification GO:0009798 43 23 1,000 0,01004963 0,05605307 ! visual behavior GO:0007632 46 23 1,000 0,01004963 0,05592539 ! regulation of DNA recombination GO:0000018 51 23 1,000 0,01004963 0,05579829 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 0,01004963 0,05567176 ! DNA modification GO:0006304 36 23 1,000 0,01004963 0,05554581 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 0,01004963 0,05542042 ! regulation of cellular response to stress GO:0080135 142 68 2,000 0,01042812 0,05737815 ! hexose catabolic process GO:0019320 113 68 2,000 0,01042812 0,05724921 ! extracellular matrix organization GO:0030198 146 68 2,000 0,01042812 0,05712085 ! viral reproduction GO:0016032 142 68 2,000 0,01042812 0,05699306 ! regulation of lipase activity GO:0060191 137 68 2,000 0,01042812 0,05686585 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 0,01091586 0,05939295 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 0,01091586 0,05926097 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 0,01091586 0,05912957 ! sex determination GO:0007530 48 24 1,000 0,01091586 0,05899875 ! membrane depolarization GO:0051899 45 24 1,000 0,01091586 0,05886851 ! oogenesis GO:0048477 44 24 1,000 0,01091586 0,05873884 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 0,01091586 0,05860975 ! negative regulation of catabolic process GO:0009895 52 24 1,000 0,01091586 0,05848122 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 0,01091586 0,05835325 ! regulation of transmembrane transport GO:0034762 39 25 1,000 0,01181381 0,0630156 ! leukocyte adhesion GO:0007159 55 25 1,000 0,01181381 0,06287831 ! vasculogenesis GO:0001570 49 25 1,000 0,01181381 0,06274162 ! chromosome condensation GO:0030261 48 25 1,000 0,01181381 0,06260552 ! interaction with host GO:0051701 66 25 1,000 0,01181381 0,06247001 ! lymphocyte proliferation GO:0046651 55 25 1,000 0,01181381 0,06233509 ! leukocyte homeostasis GO:0001776 50 25 1,000 0,01181381 0,06220074 ! protein tetramerization GO:0051262 57 25 1,000 0,01181381 0,06206698 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 0,0121737 0,06382049 ! molting cycle process GO:0022404 52 26 1,000 0,01274305 0,06666225 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 0,01274305 0,06651981 ! multicellular organismal response to stress GO:0033555 61 26 1,000 0,01274305 0,06637798 ! regulation of blood coagulation GO:0030193 46 26 1,000 0,01274305 0,06623675 ! blastocyst development GO:0001824 50 26 1,000 0,01274305 0,06609612 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 0,01274305 0,06595608 ! regulation of caspase activity GO:0043281 136 74 2,000 0,01310547 0,06768852 ! axon guidance GO:0007411 162 75 2,000 0,01358621 0,07002347 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 0,01370312 0,07047729 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 0,01370312 0,07032923 ! mitochondrial membrane organization GO:0007006 60 27 1,000 0,01370312 0,07018179 ! response to toxin GO:0009636 49 27 1,000 0,01370312 0,07003497 ! cellular response to oxidative stress GO:0034599 43 27 1,000 0,01370312 0,06988876 ! regulation of chromosome organization GO:0033044 49 27 1,000 0,01370312 0,06974315 ! leukocyte proliferation GO:0070661 59 27 1,000 0,01370312 0,06959816 GO:0032943|mononuclear cell proliferation, ! cell-matrix adhesion GO:0007160 181 76 2,000 0,0140769 0,07134826 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 0,01457755 0,0737328 ! monosaccharide catabolic process GO:0046365 125 77 2,000 0,01457755 0,07358046 ! regulation of catabolic process GO:0009894 173 77 2,000 0,01457755 0,07342875 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01469357 0,07386088 ! dendrite development GO:0016358 67 28 1,000 0,01469357 0,07370921 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 0,01560883 0,07814009 ! protein oligomerization GO:0051259 149 79 2,000 0,01560883 0,0779803 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01571397 0,07834534 ! catechol metabolic process GO:0009712 55 29 1,000 0,01571397 0,07818578 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to organic cyclic substance GO:0014070 58 29 1,000 0,01571397 0,07802686 ! somitogenesis GO:0001756 52 29 1,000 0,01571397 0,07786859 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 0,01571397 0,07771096 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 0,01571397 0,07755397 ! development of primary sexual characteristics GO:0045137 143 80 2,000 0,0161395 0,07949356 ! phenol metabolic process GO:0018958 56 30 1,000 0,01676387 0,08240269 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 0,01676387 0,08223722 ! tissue homeostasis GO:0001894 50 30 1,000 0,01676387 0,08207242 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 1,000 0,01676387 0,08190827 ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01723101 0,08402266 ! cell-substrate adhesion GO:0031589 189 82 2,000 0,01723101 0,08385528 ! ovulation cycle process GO:0022602 55 31 1,000 0,01784285 0,08666023 ! male gonad development GO:0008584 56 31 1,000 0,01784285 0,08648828 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01784285 0,08631702 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01784285 0,08614643 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01784285 0,08597652 ! response to heat GO:0009408 54 31 1,000 0,01784285 0,08580727 ! response to metal ion GO:0010038 158 84 2,000 0,01836281 0,0881343 ! regulation of ligase activity GO:0051340 147 84 2,000 0,01836281 0,08796148 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01895049 0,09059892 ! spindle organization GO:0007051 50 32 1,000 0,01895049 0,09042197 ! metanephros development GO:0001656 81 32 1,000 0,01895049 0,0902457 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01895049 0,09007013 ! ovulation cycle GO:0042698 57 32 1,000 0,01895049 0,08989524 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,01895049 0,08972102 ! response to ionizing radiation GO:0010212 74 33 1,000 0,02008635 0,09491482 ! regulation of axonogenesis GO:0050770 86 33 1,000 0,02008635 0,09473158 ! alcohol catabolic process GO:0046164 142 87 2,000 0,02013629 0,0947841 ! response to hydrogen peroxide GO:0042542 56 34 1,000 0,02125003 0,09983426 ! glial cell differentiation GO:0010001 67 34 1,000 0,02125003 0,09964264 ! post-embryonic development GO:0009791 76 34 1,000 0,02125003 0,09945175 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,02125003 0,09926159 ! tube morphogenesis GO:0035239 194 89 2,000 0,02136919 0,09962775 ! response to inorganic substance GO:0010035 173 90 2,000 0,02200084 0,10237722 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,02200084 0,10218259 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,0224411 0,10402959 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,0224411 0,10383257 ! placenta development GO:0001890 53 35 1,000 0,0224411 0,10363629 ! ossification GO:0001503 205 91 2,000 0,02264261 0,1043696 ! bone development GO:0060348 206 92 2,000 0,02329451 0,10717228 ! regulation of muscle development GO:0048634 82 36 1,000 0,02365915 0,10864531 ! positive regulation of cell development GO:0010720 85 36 1,000 0,02365915 0,10844147 ! female pregnancy GO:0007565 166 94 2,000 0,02462868 0,1126739 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,02490379 0,11371953 ! odontogenesis GO:0042476 74 37 1,000 0,02490379 0,11350737 ! actomyosin structure organization GO:0031032 68 37 1,000 0,02490379 0,113296 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,02490379 0,11308541 ! female gonad development GO:0008585 71 37 1,000 0,02490379 0,1128756 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,02490379 0,11266657 ! regulation of defense response GO:0031347 171 95 2,000 0,02531094 0,11429692 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 0,02531094 0,11408604 ! response to protein stimulus GO:0051789 158 96 2,000 0,02600332 0,11699099 ! regulation of T cell activation GO:0050863 175 96 2,000 0,02600332 0,11677593 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,0261746 0,11732945 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,0261746 0,11711456 ! glycogen metabolic process GO:0005977 63 38 1,000 0,0261746 0,11690046 ! pigment metabolic process GO:0042440 87 38 1,000 0,0261746 0,11668713 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,0274712 0,12224433 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 0,0274712 0,12202206 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,02879318 0,12766196 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,02879318 0,12743069 GO:0046660|female sex differentiation, ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,02887376 0,12755623 GO:0060538|skeletal muscle organ development, ! hormone metabolic process GO:0042445 171 100 2,000 0,02887376 0,12732598 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 0,03014016 0,13267103 ! gliogenesis GO:0042063 91 41 1,000 0,03014016 0,13243241 ! mesenchymal cell development GO:0014031 94 41 1,000 0,03014016 0,13219465 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 95 41 1,000 0,03014016 0,13195775 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,03151176 0,13771598 ! ear morphogenesis GO:0042471 64 42 1,000 0,03151176 0,13747006 ! T cell differentiation GO:0030217 93 42 1,000 0,03151176 0,13722502 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,03151176 0,13698084 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03262519 0,14156898 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03262519 0,14131797 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03262519 0,14106785 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,03262519 0,14081861 ! neuron fate determination GO:0048664 7 5 0,000 0,03262519 0,14057026 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03262519 0,14032277 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03262519 0,14007616 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,03262519 0,13983041 ! polyol transport GO:0015791 12 5 0,000 0,03262519 0,13958553 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03262519 0,13934149 ! response to superoxide GO:0000303 10 5 0,000 0,03262519 0,13909832 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03262519 0,13885598 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03262519 0,1386145 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03262519 0,13837385 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03262519 0,13813403 ! female meiosis GO:0007143 10 5 0,000 0,03262519 0,13789504 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03262519 0,13765688 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03262519 0,13741954 ! cobalt ion transport GO:0006824 11 5 0,000 0,03262519 0,13718302 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03262519 0,13694731 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03262519 0,13671241 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03262519 0,13647831 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03262519 0,13624502 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03262519 0,13601252 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,03262519 0,13578081 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03262519 0,13554989 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03262519 0,13531975 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,03262519 0,1350904 ! transposition GO:0032196 9 5 0,000 0,03262519 0,13486182 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,03262519 0,13463401 ! negative chemotaxis GO:0050919 16 5 0,000 0,03262519 0,13440697 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03262519 0,1341807 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03262519 0,13395518 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03262519 0,13373043 ! behavioral response to pain GO:0048266 10 5 0,000 0,03262519 0,13350642 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03262519 0,13328317 ! Notch receptor processing GO:0007220 11 5 0,000 0,03262519 0,13306066 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03262519 0,13283889 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,03262519 0,13261786 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03262519 0,13239757 ! copulation GO:0007620 9 5 0,000 0,03262519 0,132178 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03262519 0,13195916 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03262519 0,13174105 ! bioluminescence GO:0008218 9 5 0,000 0,03262519 0,13152366 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03262519 0,13130698 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03262519 0,13109101 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03262519 0,13087576 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,03262519 0,1306612 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03262519 0,13044736 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03262519 0,13023421 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03262519 0,13002175 ! grooming behavior GO:0007625 6 5 0,000 0,03262519 0,12980999 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03262519 0,12959892 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03262519 0,12938853 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03262519 0,12917883 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03262519 0,1289698 ! response to protozoan GO:0001562 13 5 0,000 0,03262519 0,12876145 ! lymph vessel development GO:0001945 10 5 0,000 0,03262519 0,12855377 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,03262519 0,12834676 ! endochondral ossification GO:0001958 17 5 0,000 0,03262519 0,12814041 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03262519 0,12793473 ! single strand break repair GO:0000012 8 5 0,000 0,03262519 0,1277297 ! parathyroid gland development GO:0060017 14 5 0,000 0,03262519 0,12752534 ! anagen GO:0042640 7 5 0,000 0,03262519 0,12732162 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03262519 0,12711856 ! cytokine secretion GO:0050663 15 5 0,000 0,03262519 0,12691614 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03262519 0,12671436 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03262519 0,12651323 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,03262519 0,12631273 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,03262519 0,12611287 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03262519 0,12591364 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03262519 0,12571504 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,03262519 0,12551706 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03262519 0,12531971 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03262519 0,12512297 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03262519 0,12492686 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03262519 0,12473135 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03262519 0,12453646 ! microvillus organization GO:0032528 8 5 0,000 0,03262519 0,12434218 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,03262519 0,1241485 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03262519 0,12395542 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,03262519 0,12376294 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03262519 0,12357106 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03262519 0,12337978 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03262519 0,12318908 ! polyol catabolic process GO:0046174 9 5 0,000 0,03262519 0,12299897 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03262519 0,12280945 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03262519 0,12262052 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03262519 0,12243216 ! muscle cell migration GO:0014812 8 5 0,000 0,03262519 0,12224438 ! mitochondrial fission GO:0000266 8 5 0,000 0,03262519 0,12205717 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03262519 0,12187054 ! mRNA transcription GO:0009299 10 5 0,000 0,03262519 0,12168448 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03262519 0,12149899 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03262519 0,12131406 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03262519 0,12112969 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03262519 0,12094588 ! monocyte activation GO:0042117 10 5 0,000 0,03262519 0,12076263 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03262519 0,12057993 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03262519 0,12039779 ! response to food GO:0032094 6 5 0,000 0,03262519 0,12021619 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03262519 0,12003514 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,03262519 0,11985464 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03262519 0,11967468 ! forebrain neuron development GO:0021884 13 5 0,000 0,03262519 0,11949525 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03262519 0,11931637 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,03262519 0,11913802 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03262519 0,1189602 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03262519 0,11878291 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03262519 0,11860615 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03262519 0,11842992 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,03262519 0,11825421 ! lipid glycosylation GO:0030259 7 5 0,000 0,03262519 0,11807901 ! nucleobase transport GO:0015851 6 5 0,000 0,03262519 0,11790434 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03262519 0,11773018 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03262519 0,11755654 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03262519 0,11738341 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03262519 0,11721079 ! basic amino acid transport GO:0015802 12 5 0,000 0,03262519 0,11703867 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03262519 0,11686706 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03262519 0,11669595 ! actin nucleation GO:0045010 11 5 0,000 0,03262519 0,11652534 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03262519 0,11635523 ! depurination GO:0045007 5 5 0,000 0,03262519 0,11618562 ! depyrimidination GO:0045008 10 5 0,000 0,03262519 0,1160165 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03262519 0,11584787 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03262519 0,11567973 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03262519 0,11551208 GO:0031572|G2/M transition DNA damage checkpoint, ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03262519 0,11534491 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,03262519 0,11517823 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03262519 0,11501203 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03262519 0,1148463 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03262519 0,11468106 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03262519 0,11451629 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03262519 0,11435199 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03262519 0,11418816 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03262519 0,1140248 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03262519 0,11386191 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03262519 0,11369948 ! response to arsenic GO:0046685 11 5 0,000 0,03262519 0,11353751 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,03262519 0,11337601 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03262519 0,11321496 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03262519 0,11305438 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03262519 0,11289424 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,03262519 0,11273456 ! response to mercury ion GO:0046689 8 5 0,000 0,03262519 0,11257533 ! response to cadmium ion GO:0046686 7 5 0,000 0,03262519 0,11241655 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03262519 0,11225822 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03262519 0,11210033 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03262519 0,11194289 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03262519 0,11178588 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03262519 0,11162932 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03262519 0,1114732 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03262519 0,11131751 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03262519 0,11116225 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03262519 0,11100743 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03262519 0,11085304 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,03262519 0,11069908 ! embryonic cleavage GO:0040016 6 5 0,000 0,03262519 0,11054554 ! peroxisome fission GO:0016559 5 5 0,000 0,03262519 0,11039243 ! histone demethylation GO:0016577 13 5 0,000 0,03262519 0,11023974 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03262519 0,11008748 ! mitotic recombination GO:0006312 9 5 0,000 0,03262519 0,10993563 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03262519 0,10978421 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03262519 0,1096332 ! metaphase plate congression GO:0051310 7 5 0,000 0,03262519 0,1094826 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03262519 0,10933242 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03262519 0,10918265 ! enteric nervous system development GO:0048484 8 5 0,000 0,03262519 0,10903329 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,03262519 0,10888434 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03262519 0,10873579 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03262519 0,10858765 ! muscle cell proliferation GO:0033002 12 5 0,000 0,03262519 0,10843991 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03262519 0,10829257 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,03262519 0,10814564 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03262519 0,1079991 ! metaphase GO:0051323 11 5 0,000 0,03262519 0,10785296 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03262519 0,10770721 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03262519 0,10756186 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03262519 0,10741689 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03262519 0,10727232 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03262519 0,10712814 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03262519 0,10698434 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03262519 0,10684093 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,03262519 0,10669791 ! response to redox state GO:0051775 6 5 0,000 0,03262519 0,10655526 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,03262519 0,106413 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03262519 0,10627111 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03262519 0,10612961 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03262519 0,10598848 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03262519 0,10584772 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03262519 0,10570734 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03262519 0,10556733 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03262519 0,10542769 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,03262519 0,10528842 ! striatum development GO:0021756 14 5 0,000 0,03262519 0,10514952 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03262519 0,10501098 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03262519 0,10487281 ! glial cell migration GO:0008347 10 5 0,000 0,03262519 0,104735 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03262519 0,10459755 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03262519 0,10446047 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03262519 0,10432374 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03262519 0,10418737 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03262519 0,10405135 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03262519 0,10391569 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03262519 0,10378038 ! neuroprotection GO:0043526 8 5 0,000 0,03262519 0,10364543 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03262519 0,10351082 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03262519 0,10337657 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03262519 0,10324266 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03262519 0,1031091 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03262519 0,10297589 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03262519 0,10284301 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03262519 0,10271048 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03262519 0,10257829 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03262519 0,10244645 ! spindle assembly GO:0051225 6 5 0,000 0,03262519 0,10231494 ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03262519 0,10218376 ! protein palmitoylation GO:0018345 12 5 0,000 0,03262519 0,10205293 ! drug metabolic process GO:0017144 7 5 0,000 0,03262519 0,10192242 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03262519 0,10179225 ! organ regeneration GO:0031100 7 5 0,000 0,03262519 0,10166242 ! carnitine metabolic process GO:0009437 8 5 0,000 0,03262519 0,10153291 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03262519 0,10140373 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,03290759 0,10215152 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,03290759 0,10202188 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,03290759 0,10189258 ! glucose transport GO:0015758 66 43 1,000 0,03290759 0,1017636 ! segmentation GO:0035282 78 43 1,000 0,03290759 0,10163495 ! neuron migration GO:0001764 85 43 1,000 0,03290759 0,10150662 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,03432727 0,10575225 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,03432727 0,10561906 ! hexose transport GO:0008645 68 44 1,000 0,03432727 0,1054862 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,03432727 0,10535368 ! biopolymer methylation GO:0043414 91 45 1,000 0,03577044 0,10964515 ! B cell differentiation GO:0030183 124 45 1,000 0,03577044 0,10950775 ! female gamete generation GO:0007292 71 45 1,000 0,03577044 0,10937069 ! developmental growth GO:0048589 88 45 1,000 0,03577044 0,10923398 ! maintenance of location in cell GO:0051651 101 45 1,000 0,03577044 0,10909761 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,03723672 0,11342805 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,03723672 0,1132868 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03902191 0,11857031 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03902191 0,11842301 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03902191 0,11827609 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03902191 0,11812952 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03902191 0,11798332 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03902191 0,11783748 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03902191 0,11769201 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03902191 0,11754689 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03902191 0,11740212 ! response to oxygen radical GO:0000305 11 6 0,000 0,03902191 0,11725772 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03902191 0,11711367 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03902191 0,11696997 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03902191 0,11682662 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03902191 0,11668363 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03902191 0,11654098 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03902191 0,11639869 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03902191 0,11625674 ! forebrain regionalization GO:0021871 9 6 0,000 0,03902191 0,11611513 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03902191 0,11597388 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03902191 0,11583296 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03902191 0,11569239 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03902191 0,11555215 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03902191 0,11541226 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03902191 0,1152727 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03902191 0,11513348 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03902191 0,1149946 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03902191 0,11485605 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03902191 0,11471784 ! malate metabolic process GO:0006108 13 6 0,000 0,03902191 0,11457996 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03902191 0,11444241 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03902191 0,11430519 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03902191 0,11416829 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03902191 0,11403173 ! protein refolding GO:0042026 15 6 0,000 0,03902191 0,11389549 ! opsonization GO:0008228 8 6 0,000 0,03902191 0,11375958 ! mating behavior GO:0007617 7 6 0,000 0,03902191 0,11362399 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03902191 0,11348872 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03902191 0,11335378 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03902191 0,11321915 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03902191 0,11308485 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03902191 0,11295086 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03902191 0,11281719 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03902191 0,11268384 ! toxin metabolic process GO:0009404 11 6 0,000 0,03902191 0,1125508 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03902191 0,11241807 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03902191 0,11228566 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03902191 0,11215356 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03902191 0,11202177 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03902191 0,11189029 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03902191 0,11175912 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03902191 0,11162825 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03902191 0,11149769 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03902191 0,11136744 ! thymic T cell selection GO:0045061 16 6 0,000 0,03902191 0,11123749 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03902191 0,11110784 ! protein lipoylation GO:0009249 10 6 0,000 0,03902191 0,11097849 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03902191 0,11084945 GO:0070633|transepithelial transport, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03902191 0,1107207 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03902191 0,11059226 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03902191 0,11046411 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03902191 0,11033626 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03902191 0,1102087 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03902191 0,11008144 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03902191 0,10995447 ! hyperosmotic response GO:0006972 10 6 0,000 0,03902191 0,10982779 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03902191 0,10970141 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03902191 0,10957532 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03902191 0,10944951 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03902191 0,109324 ! urea metabolic process GO:0019627 7 6 0,000 0,03902191 0,10919877 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03902191 0,10907383 ! neutrophil activation GO:0042119 7 6 0,000 0,03902191 0,10894917 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03902191 0,1088248 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03902191 0,10870071 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03902191 0,10857691 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03902191 0,10845338 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03902191 0,10833014 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03902191 0,10820718 ! neuron apoptosis GO:0051402 15 6 0,000 0,03902191 0,1080845 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03902191 0,10796209 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03902191 0,10783996 ! folic acid transport GO:0015884 14 6 0,000 0,03902191 0,10771811 ! carnitine transport GO:0015879 10 6 0,000 0,03902191 0,10759653 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03902191 0,10747523 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03902191 0,1073542 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03902191 0,10723344 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03902191 0,10711295 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03902191 0,10699273 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03902191 0,10687279 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03902191 0,10675311 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03902191 0,1066337 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03902191 0,10651455 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03902191 0,10639568 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03902191 0,10627706 ! response to UV-C GO:0010225 14 6 0,000 0,03902191 0,10615871 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03902191 0,10604063 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03902191 0,10592281 ! interaction with symbiont GO:0051702 14 6 0,000 0,03902191 0,10580524 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03902191 0,10568794 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03902191 0,1055709 ! response to copper ion GO:0046688 10 6 0,000 0,03902191 0,10545412 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03902191 0,1053376 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03902191 0,10522133 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03902191 0,10510532 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03902191 0,10498957 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03902191 0,10487407 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03902191 0,10475882 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03902191 0,10464383 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03902191 0,10452908 ! hair follicle maturation GO:0048820 8 6 0,000 0,03902191 0,1044146 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03902191 0,10430036 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03902191 0,10418637 ! response to pheromone GO:0019236 6 6 0,000 0,03902191 0,10407263 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03902191 0,10395913 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03902191 0,10384589 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03902191 0,10373289 ! subpallium development GO:0021544 15 6 0,000 0,03902191 0,10362014 ! neural tube patterning GO:0021532 8 6 0,000 0,03902191 0,10350763 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03902191 0,10339536 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03902191 0,10328334 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03902191 0,10317156 ! G2 phase GO:0051319 16 6 0,000 0,03902191 0,10306003 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03902191 0,10294873 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03902191 0,10283768 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03902191 0,10272686 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03902191 0,10261628 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03902191 0,10250594 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03902191 0,10239584 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03902191 0,10228597 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03902191 0,10217634 ! receptor internalization GO:0031623 11 6 0,000 0,03902191 0,10206694 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03902191 0,10195778 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03902191 0,10184885 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03902191 0,10174016 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03902191 0,10163169 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03902191 0,10152346 ! protein deubiquitination GO:0016579 16 6 0,000 0,03902191 0,10141545 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03902191 0,10130768 ! protein destabilization GO:0031648 9 6 0,000 0,03902191 0,10120013 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03902191 0,10109282 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03902191 0,10098573 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03902191 0,10087886 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03902191 0,10077223 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03902191 0,10066581 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03902191 0,10055963 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03902191 0,10045366 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03902191 0,10034792 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03902191 0,1002424 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03902191 0,10013711 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03902191 0,10003203 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03902191 0,09992718 ! neural plate development GO:0001840 9 6 0,000 0,03902191 0,09982254 ! catecholamine transport GO:0051937 9 6 0,000 0,03902191 0,09971812 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03902191 0,09961392 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03902191 0,09950994 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03902191 0,09940618 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03902191 0,09930263 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03902191 0,0991993 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03902191 0,09909618 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03902191 0,09899328 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03902191 0,09889059 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03902191 0,09878811 ! mitochondrial transport GO:0006839 94 48 1,000 0,04023715 0,10175916 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,04023715 0,10165392 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,04023715 0,10154891 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,04023715 0,10144411 ! methylation GO:0032259 97 48 1,000 0,04023715 0,10133953 ! response to calcium ion GO:0051592 94 49 1,000 0,04177058 0,10509322 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,04177058 0,1049851 ! JNK cascade GO:0007254 106 49 1,000 0,04177058 0,1048772 ! protein homooligomerization GO:0051260 84 49 1,000 0,04177058 0,10476953 ! endocrine system development GO:0035270 109 50 1,000 0,04332568 0,1085586 ! regulation of ossification GO:0030278 123 50 1,000 0,04332568 0,10844737 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,04332568 0,10833637 ! viral infectious cycle GO:0019058 104 51 1,000 0,0449021 0,11216343 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,0449021 0,11204886 ! response to temperature stimulus GO:0009266 84 51 1,000 0,0449021 0,11193453 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,0449021 0,11182042 ! tRNA transcription GO:0009304 17 7 0,000 0,04537651 0,11288678 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04537651 0,11277194 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04537651 0,11265734 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04537651 0,11254296 ! regulation of helicase activity GO:0051095 16 7 0,000 0,04537651 0,11242882 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,04537651 0,11231491 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04537651 0,11220123 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04537651 0,11208778 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04537651 0,11197456 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04537651 0,11186157 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04537651 0,11174881 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04537651 0,11163627 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04537651 0,11152396 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04537651 0,11141188 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04537651 0,11130002 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04537651 0,11118838 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04537651 0,11107697 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04537651 0,11096578 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04537651 0,11085482 ! glycolipid transport GO:0046836 11 7 0,000 0,04537651 0,11074407 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04537651 0,11063355 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,04537651 0,11052325 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04537651 0,11041317 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,04537651 0,1103033 ! mRNA stabilization GO:0048255 18 7 0,000 0,04537651 0,11019366 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,04537651 0,11008423 ! fibril organization GO:0043206 17 7 0,000 0,04537651 0,10997502 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,04537651 0,10986602 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04537651 0,10975725 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04537651 0,10964868 ! lipoprotein transport GO:0042953 14 7 0,000 0,04537651 0,10954033 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04537651 0,1094322 ! rhythmic behavior GO:0007622 17 7 0,000 0,04537651 0,10932428 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04537651 0,10921657 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,04537651 0,10910907 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04537651 0,10900179 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04537651 0,10889471 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,04537651 0,10878785 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04537651 0,10868119 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,04537651 0,10857475 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04537651 0,10846851 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,04537651 0,10836248 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04537651 0,10825666 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,04537651 0,10815104 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04537651 0,10804563 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04537651 0,10794043 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04537651 0,10783543 ! spinal cord patterning GO:0021511 14 7 0,000 0,04537651 0,10773063 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04537651 0,10762604 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04537651 0,10752165 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,04537651 0,10741746 ! adrenal gland development GO:0030325 17 7 0,000 0,04537651 0,10731347 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04537651 0,10720969 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04537651 0,1071061 ! ovulation GO:0030728 10 7 0,000 0,04537651 0,10700272 ! adenohypophysis development GO:0021984 11 7 0,000 0,04537651 0,10689954 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,04537651 0,10679655 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,04537651 0,10669376 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,04537651 0,10659117 ! microtubule nucleation GO:0007020 21 7 0,000 0,04537651 0,10648878 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04537651 0,10638658 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,04537651 0,10628458 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04537651 0,10618278 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04537651 0,10608117 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04537651 0,10597975 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04537651 0,10587853 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04537651 0,1057775 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04537651 0,10567666 ! galactose metabolic process GO:0006012 13 7 0,000 0,04537651 0,10557602 ! vesicle fusion GO:0006906 20 7 0,000 0,04537651 0,10547556 ! response to dietary excess GO:0002021 8 7 0,000 0,04537651 0,1053753 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04537651 0,10527523 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04537651 0,10517535 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04537651 0,10507566 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,04537651 0,10497615 ! nucleoside transport GO:0015858 11 7 0,000 0,04537651 0,10487684 ! nucleoside salvage GO:0043174 11 7 0,000 0,04537651 0,10477771 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04537651 0,10467877 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04537651 0,10458002 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,04537651 0,10448145 ! parturition GO:0007567 16 7 0,000 0,04537651 0,10438307 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,04537651 0,10428487 ! rRNA modification GO:0000154 14 7 0,000 0,04537651 0,10418686 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04537651 0,10408903 ! spindle checkpoint GO:0031577 16 7 0,000 0,04537651 0,10399139 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04537651 0,10389393 ! monocyte differentiation GO:0030224 16 7 0,000 0,04537651 0,10379665 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04537651 0,10369955 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04537651 0,10360263 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,04537651 0,1035059 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04537651 0,10340935 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,04537651 0,10331297 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04537651 0,10321678 ! fibrinolysis GO:0042730 11 7 0,000 0,04537651 0,10312076 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04537651 0,10302492 ! eating behavior GO:0042755 8 7 0,000 0,04537651 0,10292926 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04537651 0,10283378 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04537651 0,10273848 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04537651 0,10264335 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04537651 0,1025484 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,04537651 0,10245362 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04537651 0,10235902 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,04537651 0,10226459 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,04537651 0,10217034 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04537651 0,10207626 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04537651 0,10198235 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04537651 0,10188862 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04537651 0,10179506 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04537651 0,10170167 ! histone ubiquitination GO:0016574 9 7 0,000 0,04537651 0,10160845 ! regulation of meiosis GO:0040020 12 7 0,000 0,04537651 0,1015154 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,04537651 0,10142252 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04537651 0,10132982 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04537651 0,10123728 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04537651 0,10114491 ! transcription termination GO:0006353 14 7 0,000 0,04537651 0,10105271 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04537651 0,10096067 ! anaphase GO:0051322 18 7 0,000 0,04537651 0,10086881 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,04537651 0,10077711 ! axonal fasciculation GO:0007413 19 7 0,000 0,04537651 0,10068558 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,04537651 0,10059421 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,04537651 0,10050301 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04537651 0,10041197 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,04537651 0,1003211 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04537651 0,1002304 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04537651 0,10013985 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04537651 0,10004948 ! antibiotic transport GO:0042891 9 7 0,000 0,04537651 0,09995926 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04537651 0,09986921 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04537651 0,09977931 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,04537651 0,09968958 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04537651 0,09960002 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04537651 0,09951061 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04537651 0,09942136 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,04537651 0,09933227 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04537651 0,09924335 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04537651 0,09915458 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04537651 0,09906597 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,04537651 0,09897752 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04537651 0,09888922 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04537651 0,09880109 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04537651 0,09871311 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04537651 0,09862528 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04537651 0,09853762 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04537651 0,09845011 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04537651 0,09836275 ! muscle adaptation GO:0043500 13 7 0,000 0,04537651 0,09827555 ! embryonic heart tube development GO:0035050 14 7 0,000 0,04537651 0,0981885 ! retina homeostasis GO:0001895 12 7 0,000 0,04537651 0,09810161 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04537651 0,09801487 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04537651 0,09792828 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,04537651 0,09784185 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,04537651 0,09775557 ! positive regulation of binding GO:0051099 88 52 1,000 0,0464995 0,10008658 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,0464995 0,09999848 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,0464995 0,09991053 ! cellular amino acid biosynthetic process GO:0008652 80 52 1,000 0,0464995 0,09982273 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,0464995 0,09973509 ! histone modification GO:0016570 104 52 1,000 0,0464995 0,09964761 ! vesicle organization GO:0016050 127 53 1,000 0,04811752 0,10302463 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,04811752 0,10293442 ! synapse organization GO:0050808 102 53 1,000 0,04811752 0,10284436 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,04975584 0,10625306 ! neuromuscular process GO:0050905 107 54 1,000 0,04975584 0,10616027 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,04975584 0,10606763 ! covalent chromatin modification GO:0016569 115 54 1,000 0,04975584 0,10597516 ! regulation of cell shape GO:0008360 142 54 1,000 0,04975584 0,10588285 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,04975584 0,10579069 ! cell maturation GO:0048469 107 55 1,000 0,0514141 0,10922144 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,05168927 0,10971059 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,05168927 0,10961535 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,05168927 0,10952029 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,05168927 0,10942538 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,05168927 0,10933064 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05168927 0,10923606 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05168927 0,10914165 ! male meiosis GO:0007140 9 8 0,000 0,05168927 0,1090474 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,05168927 0,10895331 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,05168927 0,10885939 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,05168927 0,10876562 ! meiotic prophase I GO:0007128 14 8 0,000 0,05168927 0,10867202 ! response to zinc ion GO:0010043 12 8 0,000 0,05168927 0,10857858 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,05168927 0,1084853 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05168927 0,10839218 ! oligopeptide transport GO:0006857 16 8 0,000 0,05168927 0,10829922 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,05168927 0,10820642 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,05168927 0,10811377 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,05168927 0,10802129 ! signal peptide processing GO:0006465 12 8 0,000 0,05168927 0,10792896 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,05168927 0,1078368 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,05168927 0,10774479 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05168927 0,10765293 ! succinate metabolic process GO:0006105 17 8 0,000 0,05168927 0,10756123 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,05168927 0,10746969 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,05168927 0,10737831 ! estrogen metabolic process GO:0008210 17 8 0,000 0,05168927 0,10728708 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,05168927 0,107196 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,05168927 0,10710508 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,05168927 0,10701431 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05168927 0,1069237 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05168927 0,10683324 ! reflex GO:0060004 17 8 0,000 0,05168927 0,10674293 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05168927 0,10665278 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,05168927 0,10656278 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,05168927 0,10647292 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05168927 0,10638323 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,05168927 0,10629368 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,05168927 0,10620428 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,05168927 0,10611503 ! histidine catabolic process GO:0006548 10 8 0,000 0,05168927 0,10602594 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05168927 0,10593699 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,05168927 0,10584819 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,05168927 0,10575954 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,05168927 0,10567104 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,05168927 0,10558268 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,05168927 0,10549448 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,05168927 0,10540642 ! macrophage activation GO:0042116 13 8 0,000 0,05168927 0,10531851 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05168927 0,10523074 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,05168927 0,10514312 ! purine salvage GO:0043101 12 8 0,000 0,05168927 0,10505565 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,05168927 0,10496832 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05168927 0,10488114 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,05168927 0,1047941 ! osteoblast development GO:0002076 17 8 0,000 0,05168927 0,1047072 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,05168927 0,10462045 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,05168927 0,10453385 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,05168927 0,10444739 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05168927 0,10436107 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,05168927 0,10427489 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05168927 0,10418885 ! intermediate filament organization GO:0045109 12 8 0,000 0,05168927 0,10410296 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,05168927 0,10401721 ! cellular extravasation GO:0045123 13 8 0,000 0,05168927 0,1039316 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,05168927 0,10384613 ! response to antibiotic GO:0046677 11 8 0,000 0,05168927 0,1037608 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,05168927 0,10367561 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,05168927 0,10359056 ! response to tropane GO:0014073 15 8 0,000 0,05168927 0,10350565 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,05168927 0,10342088 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,05168927 0,10333624 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05168927 0,10325175 ! mast cell activation GO:0045576 14 8 0,000 0,05168927 0,10316739 ! multicellular organismal aging GO:0010259 20 8 0,000 0,05168927 0,10308317 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,05168927 0,10299909 ! gas homeostasis GO:0033483 14 8 0,000 0,05168927 0,10291515 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,05168927 0,10283134 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,05168927 0,10274767 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,05168927 0,10266414 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05168927 0,10258074 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05168927 0,10249747 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,05168927 0,10241435 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05168927 0,10233135 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,05168927 0,10224849 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,05168927 0,10216577 ! intracellular lipid transport GO:0032365 16 8 0,000 0,05168927 0,10208318 ! response to tumor cell GO:0002347 16 8 0,000 0,05168927 0,10200072 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05168927 0,10191839 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,05168927 0,1018362 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,05168927 0,10175414 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05168927 0,10167221 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,05168927 0,10159042 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,05168927 0,10150875 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,05168927 0,10142722 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,05168927 0,10134582 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,05168927 0,10126455 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,05168927 0,1011834 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05168927 0,10110239 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,05168927 0,10102151 ! adult feeding behavior GO:0008343 10 8 0,000 0,05168927 0,10094076 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,05168927 0,10086013 ! ATP catabolic process GO:0006200 11 8 0,000 0,05168927 0,10077964 ! blastocyst growth GO:0001832 19 8 0,000 0,05168927 0,10069927 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05168927 0,10061903 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,05168927 0,10053892 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05168927 0,10045894 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,05168927 0,10037908 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,05168927 0,10029936 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,05168927 0,10021975 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,05168927 0,10014028 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,05168927 0,10006093 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,05168927 0,0999817 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05168927 0,0999026 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,05168927 0,09982363 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,05168927 0,09974478 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05168927 0,09966605 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,05168927 0,09958745 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,05168927 0,09950897 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,05168927 0,09943062 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,05168927 0,09935239 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,05168927 0,09927428 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,05168927 0,0991963 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,05309199 0,10180826 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,05309199 0,10172841 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,05309199 0,10164869 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,05478916 0,10481592 ! muscle fiber development GO:0048747 131 57 1,000 0,05478916 0,1047339 ! heart morphogenesis GO:0003007 105 57 1,000 0,05478916 0,10465202 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,05650531 0,10784567 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,05650531 0,10776149 ! maintenance of location GO:0051235 124 58 1,000 0,05650531 0,10767743 ! axon extension GO:0048675 16 9 0,000 0,05796046 0,11036431 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05796046 0,11027835 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05796046 0,11019253 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05796046 0,11010685 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05796046 0,1100213 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05796046 0,10993587 ! reproductive behavior GO:0019098 22 9 0,000 0,05796046 0,10985059 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05796046 0,10976543 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05796046 0,10968041 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05796046 0,10959552 ! UTP metabolic process GO:0046051 10 9 0,000 0,05796046 0,10951076 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05796046 0,10942613 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05796046 0,10934163 ! artery development GO:0060840 25 9 0,000 0,05796046 0,10925726 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05796046 0,10917302 ! equilibrioception GO:0050957 20 9 0,000 0,05796046 0,10908891 ! chemosensory behavior GO:0007635 21 9 0,000 0,05796046 0,10900493 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05796046 0,10892108 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05796046 0,10883736 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05796046 0,10875377 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05796046 0,1086703 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05796046 0,10858697 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05796046 0,10850376 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05796046 0,10842068 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05796046 0,10833773 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05796046 0,1082549 ! protein targeting to ER GO:0045047 25 9 0,000 0,05796046 0,1081722 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05796046 0,10808962 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05796046 0,10800718 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05796046 0,10792485 ! glycine catabolic process GO:0006546 15 9 0,000 0,05796046 0,10784266 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05796046 0,10776058 ! endosome organization GO:0007032 20 9 0,000 0,05796046 0,10767864 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05796046 0,10759681 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05796046 0,10751512 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05796046 0,10743354 ! mannose metabolic process GO:0006013 13 9 0,000 0,05796046 0,10735209 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05796046 0,10727076 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05796046 0,10718956 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05796046 0,10710848 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05796046 0,10702752 ! receptor clustering GO:0043113 20 9 0,000 0,05796046 0,10694668 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05796046 0,10686597 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05796046 0,10678537 ! retinol metabolic process GO:0042572 20 9 0,000 0,05796046 0,1067049 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05796046 0,10662455 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05796046 0,10654432 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05796046 0,10646422 ! macrophage differentiation GO:0030225 15 9 0,000 0,05796046 0,10638423 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05796046 0,10630436 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,05796046 0,10622461 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05796046 0,10614498 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05796046 0,10606547 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05796046 0,10598608 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05796046 0,10590681 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05796046 0,10582766 ! erythrocyte development GO:0048821 17 9 0,000 0,05796046 0,10574862 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05796046 0,10566971 ! renal water homeostasis GO:0003091 15 9 0,000 0,05796046 0,10559091 ! postreplication repair GO:0006301 25 9 0,000 0,05796046 0,10551223 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05796046 0,10543366 ! icosanoid secretion GO:0032309 15 9 0,000 0,05796046 0,10535521 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05796046 0,10527688 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05796046 0,10519867 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05796046 0,10512057 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05796046 0,10504259 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05796046 0,10496472 ! sterol catabolic process GO:0016127 14 9 0,000 0,05796046 0,10488697 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05796046 0,10480933 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05796046 0,10473181 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05796046 0,1046544 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05796046 0,10457711 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05796046 0,10449993 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,05796046 0,10442287 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05796046 0,10434592 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05796046 0,10426908 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05796046 0,10419235 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05796046 0,10411574 ! purine base metabolic process GO:0006144 25 9 0,000 0,05796046 0,10403924 ! pigment granule transport GO:0051904 17 9 0,000 0,05796046 0,10396285 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05796046 0,10388658 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05796046 0,10381042 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05796046 0,10373436 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05796046 0,10365842 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05796046 0,10358259 ! mitochondrion localization GO:0051646 18 9 0,000 0,05796046 0,10350688 ! lipid modification GO:0030258 112 60 1,000 0,05999319 0,10705871 ! kidney development GO:0001822 133 60 1,000 0,05999319 0,10698057 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,06419036 0,1143815 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,06419036 0,11429813 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06419036 0,11421489 ! associative learning GO:0008306 21 10 0,000 0,06419036 0,11413176 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06419036 0,11404876 ! phosphate transport GO:0006817 24 10 0,000 0,06419036 0,11396587 ! cell volume homeostasis GO:0006884 17 10 0,000 0,06419036 0,11388311 ! CTP metabolic process GO:0046036 11 10 0,000 0,06419036 0,11380046 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,06419036 0,11371794 ! GTP metabolic process GO:0046039 11 10 0,000 0,06419036 0,11363554 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,06419036 0,11355325 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,06419036 0,11347108 ! social behavior GO:0035176 29 10 0,000 0,06419036 0,11338904 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,06419036 0,11330711 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,06419036 0,1132253 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,06419036 0,11314361 ! androgen metabolic process GO:0008209 17 10 0,000 0,06419036 0,11306203 ! phospholipid efflux GO:0033700 19 10 0,000 0,06419036 0,11298058 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06419036 0,11289924 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,06419036 0,11281801 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,06419036 0,11273691 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,06419036 0,11265592 ! lung alveolus development GO:0048286 26 10 0,000 0,06419036 0,11257505 ! pathogenesis GO:0009405 17 10 0,000 0,06419036 0,11249429 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06419036 0,11241365 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,06419036 0,11233312 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,06419036 0,11225271 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,06419036 0,11217242 ! endoderm development GO:0007492 18 10 0,000 0,06419036 0,11209224 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,06419036 0,11201217 ! arginine catabolic process GO:0006527 17 10 0,000 0,06419036 0,11193222 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06419036 0,11185238 ! proline metabolic process GO:0006560 13 10 0,000 0,06419036 0,11177266 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06419036 0,11169305 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,06419036 0,11161355 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,06419036 0,11153417 ! V(D)J recombination GO:0033151 34 10 0,000 0,06419036 0,1114549 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,06419036 0,11137574 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,06419036 0,11129669 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,06419036 0,11121776 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,06419036 0,11113894 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,06419036 0,11106023 ! multicellular organism growth GO:0035264 19 10 0,000 0,06419036 0,11098163 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,06419036 0,11090314 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,06419036 0,11082476 ! ruffle organization GO:0031529 17 10 0,000 0,06419036 0,1107465 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,06419036 0,11066834 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06419036 0,1105903 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,06419036 0,11051236 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,06419036 0,11043453 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,06419036 0,11035682 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,06419036 0,11027921 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,06419036 0,11020171 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06419036 0,11012432 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06419036 0,11004704 ! brain morphogenesis GO:0048854 23 10 0,000 0,06419036 0,10996987 ! segment specification GO:0007379 15 10 0,000 0,06419036 0,10989281 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,06419036 0,10981585 ! blastoderm segmentation GO:0007350 19 10 0,000 0,06419036 0,10973901 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,06419036 0,10966226 ! response to dsRNA GO:0043331 23 10 0,000 0,06419036 0,10958563 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,06419036 0,10950911 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06419036 0,10943269 ! melanosome localization GO:0032400 16 10 0,000 0,06419036 0,10935637 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,06419036 0,10928017 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,06419036 0,10920407 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,06419036 0,10912807 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06419036 0,10905218 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,06419036 0,1089764 ! induction of an organ GO:0001759 17 10 0,000 0,06419036 0,10890072 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,06419036 0,10882515 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,06419036 0,10874968 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,06419036 0,10867432 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06419036 0,10859906 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06419036 0,1085239 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06419036 0,10844885 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,06419036 0,1083739 ! salivary gland development GO:0007431 28 10 0,000 0,06419036 0,10829906 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,06419036 0,10822432 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,06419036 0,10814968 ! midbrain development GO:0030901 14 10 0,000 0,06419036 0,10807515 ! musculoskeletal movement GO:0050881 16 10 0,000 0,06419036 0,10800072 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,06419036 0,10792639 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,06419036 0,10785216 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,06419036 0,10777803 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,06419036 0,10770401 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,06419036 0,10763009 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06419036 0,10755627 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06419036 0,10748255 ! detection of calcium ion GO:0005513 24 10 0,000 0,06419036 0,10740893 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06419036 0,10733541 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,06419036 0,107262 ! cerebellar cortex development GO:0021695 16 10 0,000 0,06419036 0,10718868 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,06419036 0,10711546 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,06419036 0,10704235 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,06419036 0,10696933 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06419036 0,10689641 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,06718258 0,11180316 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,06902263 0,11478713 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,07037922 0,11696357 ! respiratory burst GO:0045730 17 11 0,000 0,07037922 0,11688406 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,07037922 0,11680465 ! neuron fate specification GO:0048665 18 11 0,000 0,07037922 0,11672535 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,07037922 0,11664616 ! thyroid gland development GO:0030878 26 11 0,000 0,07037922 0,11656708 ! synapsis GO:0007129 14 11 0,000 0,07037922 0,11648811 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,07037922 0,11640924 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,07037922 0,11633048 ! response to pain GO:0048265 27 11 0,000 0,07037922 0,11625182 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,07037922 0,11617327 ! blood vessel remodeling GO:0001974 30 11 0,000 0,07037922 0,11609483 ! bone resorption GO:0045453 16 11 0,000 0,07037922 0,11601649 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,07037922 0,11593826 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07037922 0,11586014 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07037922 0,11578212 ! melanocyte differentiation GO:0030318 20 11 0,000 0,07037922 0,1157042 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,07037922 0,11562639 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,07037922 0,11554869 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,07037922 0,11547108 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,07037922 0,11539359 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,07037922 0,11531619 ! UV protection GO:0009650 20 11 0,000 0,07037922 0,1152389 ! adult heart development GO:0007512 16 11 0,000 0,07037922 0,11516172 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07037922 0,11508464 ! macroautophagy GO:0016236 19 11 0,000 0,07037922 0,11500766 ! temperature homeostasis GO:0001659 18 11 0,000 0,07037922 0,11493078 ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,07037922 0,114854 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,07037922 0,11477733 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,07037922 0,11470076 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,07037922 0,1146243 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,07037922 0,11454793 ! regulation of organ growth GO:0046620 14 11 0,000 0,07037922 0,11447167 ! pigment granule localization GO:0051875 20 11 0,000 0,07037922 0,11439551 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,07037922 0,11431944 ! vasoconstriction GO:0042310 20 11 0,000 0,07037922 0,11424349 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,07037922 0,11416763 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07037922 0,11409187 ! embryonic axis specification GO:0000578 19 11 0,000 0,07037922 0,11401621 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,07037922 0,11394065 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07037922 0,1138652 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,07037922 0,11378984 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,07037922 0,11371458 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,07037922 0,11363942 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,07037922 0,11356436 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,07037922 0,1134894 ! prophase GO:0051324 17 11 0,000 0,07037922 0,11341454 ! nucleosome positioning GO:0016584 15 11 0,000 0,07037922 0,11333978 ! regulation of isotype switching GO:0045191 24 11 0,000 0,07037922 0,11326512 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,07037922 0,11319055 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,07037922 0,11311608 ! acid secretion GO:0046717 20 11 0,000 0,07037922 0,11304171 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07037922 0,11296744 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,07037922 0,11289327 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,07037922 0,11281919 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,07037922 0,11274521 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,07037922 0,11267133 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,07037922 0,11259754 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,07037922 0,11252385 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07037922 0,11245026 ! germ cell migration GO:0008354 26 11 0,000 0,07037922 0,11237676 ! embryonic gut development GO:0048566 19 11 0,000 0,07037922 0,11230336 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,07037922 0,11223006 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,07037922 0,11215685 ! activation of innate immune response GO:0002218 16 11 0,000 0,07037922 0,11208373 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,07037922 0,11201071 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,07037922 0,11193779 ! lysogeny GO:0030069 22 11 0,000 0,07037922 0,11186496 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07037922 0,11179223 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,07037922 0,11171959 ! sequestering of metal ion GO:0051238 15 11 0,000 0,07037922 0,11164704 ! nucleus localization GO:0051647 22 11 0,000 0,07037922 0,11157459 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,07087916 0,11229428 ! gonad development GO:0008406 115 66 1,000 0,07087916 0,11222151 ! secondary metabolic process GO:0019748 125 67 1,000 0,07275187 0,11511193 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,07464047 0,11802373 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,07464047 0,11794739 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,07464047 0,11787115 ! cell projection assembly GO:0030031 138 68 1,000 0,07464047 0,117795 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,07652734 0,12069483 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,07652734 0,12061696 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,07652734 0,12053919 ! mating GO:0007618 17 12 0,000 0,07652734 0,12046152 ! protein complex disassembly GO:0043241 28 12 0,000 0,07652734 0,12038396 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07652734 0,12030649 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,07652734 0,12022912 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,07652734 0,12015185 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,07652734 0,12007468 ! T cell proliferation GO:0042098 32 12 0,000 0,07652734 0,11999761 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07652734 0,11992064 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,07652734 0,11984377 ! ventral spinal cord development GO:0021517 25 12 0,000 0,07652734 0,119767 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,07652734 0,11969032 ! drug transport GO:0015893 16 12 0,000 0,07652734 0,11961375 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,07652734 0,11953727 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,07652734 0,11946088 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,07652734 0,1193846 ! polyamine metabolic process GO:0006595 18 12 0,000 0,07652734 0,11930841 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,07652734 0,11923232 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,07652734 0,11915633 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 21 12 0,000 0,07652734 0,11908044 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,07652734 0,11900464 ! entry into host cell GO:0030260 34 12 0,000 0,07652734 0,11892893 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07652734 0,11885333 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,07652734 0,11877782 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,07652734 0,1187024 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07652734 0,11862708 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,07652734 0,11855186 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,07652734 0,11847673 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,07652734 0,1184017 ! snRNA metabolic process GO:0016073 30 12 0,000 0,07652734 0,11832676 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,07652734 0,11825192 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,07652734 0,11817717 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07652734 0,11810252 ! fucose catabolic process GO:0019317 25 12 0,000 0,07652734 0,11802796 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,07652734 0,11795349 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,07652734 0,11787912 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,07652734 0,11780484 ! zymogen activation GO:0031638 18 12 0,000 0,07652734 0,11773066 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,07652734 0,11765657 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,07652734 0,11758257 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,07652734 0,11750866 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,07652734 0,11743485 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,07652734 0,11736113 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,07652734 0,11728751 ! defense response to fungus GO:0050832 15 12 0,000 0,07652734 0,11721397 ! developmental induction GO:0031128 22 12 0,000 0,07652734 0,11714053 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,07652734 0,11706718 ! response to cold GO:0009409 17 12 0,000 0,07652734 0,11699392 ! establishment of cell polarity GO:0030010 21 12 0,000 0,07652734 0,11692075 ! regulation of synapse organization GO:0050807 18 12 0,000 0,07652734 0,11684768 ! cellular hormone metabolic process GO:0034754 120 69 1,000 0,07654466 0,11680113 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,07654466 0,11672822 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,07654466 0,11665541 ! developmental maturation GO:0021700 128 69 1,000 0,07654466 0,11658268 ! germ cell development GO:0007281 133 70 1,000 0,07846417 0,11943176 ! carbohydrate transport GO:0008643 114 72 1,000 0,082348 0,12526535 ! B cell activation GO:0042113 179 72 1,000 0,082348 0,1251874 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,082348 0,12510955 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,082348 0,1250318 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08263496 0,12538957 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,08263496 0,12531174 ! regulation of chemokine production GO:0032642 18 13 0,000 0,08263496 0,125234 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08263496 0,12515636 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,08263496 0,12507882 ! peroxisomal transport GO:0043574 28 13 0,000 0,08263496 0,12500137 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,08263496 0,12492401 ! cartilage condensation GO:0001502 22 13 0,000 0,08263496 0,12484676 ! organelle fusion GO:0048284 36 13 0,000 0,08263496 0,1247696 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,08263496 0,12469253 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,08263496 0,12461556 ! endocrine pancreas development GO:0031018 25 13 0,000 0,08263496 0,12453868 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,08263496 0,1244619 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,08263496 0,12438522 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,08263496 0,12430863 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,08263496 0,12423213 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,08263496 0,12415572 ! methionine metabolic process GO:0006555 31 13 0,000 0,08263496 0,12407941 ! plasma membrane organization GO:0007009 27 13 0,000 0,08263496 0,1240032 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,08263496 0,12392708 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,08263496 0,12385105 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,08263496 0,12377511 ! response to X-ray GO:0010165 28 13 0,000 0,08263496 0,12369927 ! cytokine metabolic process GO:0042107 24 13 0,000 0,08263496 0,12362352 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,08263496 0,12354786 ! exocrine system development GO:0035272 34 13 0,000 0,08263496 0,1234723 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,08263496 0,12339683 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,08263496 0,12332145 ! L-glutamate transport GO:0015813 30 13 0,000 0,08263496 0,12324616 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,08263496 0,12317096 ! protein homotetramerization GO:0051289 24 13 0,000 0,08263496 0,12309586 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,08263496 0,12302085 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,08263496 0,12294592 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,08263496 0,12287109 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,08263496 0,12279636 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,08263496 0,12272171 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08263496 0,12264715 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,08263496 0,12257268 ! histone methylation GO:0016571 29 13 0,000 0,08263496 0,12249831 ! chromatin silencing GO:0006342 29 13 0,000 0,08263496 0,12242402 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,08263496 0,12234982 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,08263496 0,12227572 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08263496 0,1222017 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,08263496 0,12212777 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,08263496 0,12205393 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,08263496 0,12198019 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,08263496 0,12190653 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,08263496 0,12183296 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,08263496 0,12175947 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,08263496 0,12168608 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,08263496 0,12161278 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,08263496 0,12153956 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,08263496 0,12146643 ! insulin secretion GO:0030073 24 13 0,000 0,08263496 0,12139339 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,08263496 0,12132044 ! acrosome reaction GO:0007340 19 13 0,000 0,08263496 0,12124757 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,08263496 0,12117479 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,08263496 0,1211021 ! humoral immune response GO:0006959 115 73 1,000 0,08431175 0,12348538 ! amino acid transport GO:0006865 148 74 1,000 0,08628971 0,12630662 ! rhythmic process GO:0048511 142 75 1,000 0,08828158 0,12914486 ! rRNA transcription GO:0009303 28 14 0,000 0,08870236 0,12968274 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,08870236 0,12960518 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,08870236 0,12952771 ! water transport GO:0006833 21 14 0,000 0,08870236 0,12945034 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,08870236 0,12937305 ! non-recombinational repair GO:0000726 29 14 0,000 0,08870236 0,12929586 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,08870236 0,12921876 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,08870236 0,12914176 ! RNA polyadenylation GO:0043631 32 14 0,000 0,08870236 0,12906484 ! lipid localization GO:0010876 32 14 0,000 0,08870236 0,12898802 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,08870236 0,12891128 ! regulated secretory pathway GO:0045055 24 14 0,000 0,08870236 0,12883464 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,08870236 0,12875809 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,08870236 0,12868163 ! arginine metabolic process GO:0006525 21 14 0,000 0,08870236 0,12860526 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,08870236 0,12852898 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,08870236 0,1284528 ! regulation of heart rate GO:0002027 25 14 0,000 0,08870236 0,1283767 ! organic alcohol transport GO:0015850 29 14 0,000 0,08870236 0,12830069 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,08870236 0,12822477 ! embryo implantation GO:0007566 30 14 0,000 0,08870236 0,12814895 ! neutral amino acid transport GO:0015804 28 14 0,000 0,08870236 0,12807321 ! bone mineralization GO:0030282 18 14 0,000 0,08870236 0,12799756 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,08870236 0,127922 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,08870236 0,12784653 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,08870236 0,12777115 ! regulation of cellular pH GO:0030641 27 14 0,000 0,08870236 0,12769586 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,08870236 0,12762065 ! ribosome assembly GO:0042255 18 14 0,000 0,08870236 0,12754554 ! cerebellum development GO:0021549 23 14 0,000 0,08870236 0,12747051 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,08870236 0,12739557 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,08870236 0,12732072 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,08870236 0,12724596 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,08870236 0,12717128 ! NADP metabolic process GO:0006739 24 14 0,000 0,08870236 0,1270967 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,08870236 0,1270222 ! oxygen transport GO:0015671 22 14 0,000 0,08870236 0,12694778 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08870236 0,12687346 ! regulation of RNA stability GO:0043487 33 14 0,000 0,08870236 0,12679922 ! regulation of axon extension GO:0030516 43 14 0,000 0,08870236 0,12672507 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,08870236 0,126651 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,08870236 0,12657702 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,09028712 0,12876324 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,09230604 0,13156572 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,09230604 0,13148901 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,09433809 0,13430533 ! lactation GO:0007595 30 15 0,000 0,0947298 0,13478445 ! reproductive cellular process GO:0048610 22 15 0,000 0,0947298 0,134706 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0947298 0,13462763 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0947298 0,13454936 ! superoxide anion generation GO:0042554 22 15 0,000 0,0947298 0,13447118 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0947298 0,13439309 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0947298 0,13431509 ! copper ion transport GO:0006825 22 15 0,000 0,0947298 0,13423718 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0947298 0,13415936 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0947298 0,13408164 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0947298 0,134004 ! sulfate transport GO:0008272 27 15 0,000 0,0947298 0,13392645 ! response to cAMP GO:0051591 25 15 0,000 0,0947298 0,13384899 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0947298 0,13377162 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0947298 0,13369434 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0947298 0,13361715 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0947298 0,13354005 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0947298 0,13346303 ! vesicle coating GO:0006901 38 15 0,000 0,0947298 0,13338611 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,0947298 0,13330928 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,0947298 0,13323253 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0947298 0,13315587 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0947298 0,1330793 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,0947298 0,13300282 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0947298 0,13292642 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0947298 0,13285012 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0947298 0,1327739 ! regulation of vasodilation GO:0042312 27 15 0,000 0,0947298 0,13269776 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0947298 0,13262172 ! histone deacetylation GO:0016575 24 15 0,000 0,0947298 0,13254576 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0947298 0,13246989 ! water homeostasis GO:0030104 28 15 0,000 0,0947298 0,13239411 ! cofactor transport GO:0051181 30 15 0,000 0,0947298 0,13231841 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0947298 0,1322428 ! muscle maintenance GO:0046716 26 15 0,000 0,0947298 0,13216728 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0947298 0,13209184 ! intestinal absorption GO:0050892 31 15 0,000 0,0947298 0,13201649 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0947298 0,13194122 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0947298 0,13186604 ! cell killing GO:0001906 32 15 0,000 0,0947298 0,13179095 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,0947298 0,13171594 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0947298 0,13164101 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0947298 0,13156618 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0947298 0,13149142 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0947298 0,13141675 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,096383 0,13363432 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,09844053 0,13640965 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,09844053 0,13633232 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,10071754 0,13940677 ! positive regulation of cell size GO:0045793 29 16 0,000 0,10071754 0,13932783 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,10071754 0,13924899 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,10071754 0,13917022 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,10071754 0,13909155 ! bone remodeling GO:0046849 28 16 0,000 0,10071754 0,13901297 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,10071754 0,13893448 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,10071754 0,13885607 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,10071754 0,13877775 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,10071754 0,13869952 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,10071754 0,13862138 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,10071754 0,13854333 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,10071754 0,13846537 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,10071754 0,13838749 ! protein polyubiquitination GO:0000209 41 16 0,000 0,10071754 0,1383097 ! glutamate metabolic process GO:0006536 25 16 0,000 0,10071754 0,138232 ! response to osmotic stress GO:0006970 27 16 0,000 0,10071754 0,13815438 ! lysosomal transport GO:0007041 31 16 0,000 0,10071754 0,13807686 ! fructose metabolic process GO:0006000 25 16 0,000 0,10071754 0,13799941 ! L-amino acid transport GO:0015807 33 16 0,000 0,10071754 0,13792206 ! stem cell development GO:0048864 46 16 0,000 0,10071754 0,13784479 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10071754 0,13776761 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,10071754 0,13769052 ! intermediate filament-based process GO:0045103 36 16 0,000 0,10071754 0,13761351 ! negative regulation of immune response GO:0050777 38 16 0,000 0,10071754 0,13753659 ! axon cargo transport GO:0008088 46 16 0,000 0,10071754 0,13745975 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,10071754 0,137383 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,10071754 0,13730634 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,10071754 0,13722976 ! neuron recognition GO:0008038 40 16 0,000 0,10071754 0,13715326 ! mRNA splice site selection GO:0006376 44 16 0,000 0,10071754 0,13707686 ! tissue regeneration GO:0042246 27 16 0,000 0,10071754 0,13700053 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,10071754 0,13692429 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,10071754 0,13684814 ! biomineral formation GO:0031214 22 16 0,000 0,10071754 0,13677207 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,10071754 0,13669609 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,10071754 0,13662019 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,10071754 0,13654437 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10071754 0,13646864 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,10071754 0,13639299 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,10071754 0,13631743 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,10071754 0,13624195 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,10071754 0,13616655 ! peptide hormone processing GO:0016486 27 16 0,000 0,10071754 0,13609124 ! protein import into nucleus GO:0006606 174 82 1,000 0,10259239 0,13854794 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,10468623 0,1412975 ! nuclear import GO:0051170 177 83 1,000 0,10468623 0,14121948 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,10666585 0,14381052 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,10666585 0,1437312 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,10666585 0,14365197 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,10666585 0,14357282 ! signal complex assembly GO:0007172 47 17 0,000 0,10666585 0,14349376 ! filopodium assembly GO:0046847 42 17 0,000 0,10666585 0,14341479 ! endothelial cell migration GO:0043542 31 17 0,000 0,10666585 0,1433359 ! gene silencing by RNA GO:0031047 38 17 0,000 0,10666585 0,1432571 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,10666585 0,14317839 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,10666585 0,14309976 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,10666585 0,14302122 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,10666585 0,14294277 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,10666585 0,1428644 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,10666585 0,14278612 ! myoblast differentiation GO:0045445 50 17 0,000 0,10666585 0,14270792 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,10666585 0,14262981 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,10666585 0,14255179 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,10666585 0,14247385 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,10666585 0,14239599 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,10666585 0,14231822 ! NAD metabolic process GO:0019674 33 17 0,000 0,10666585 0,14224054 ! membrane budding GO:0006900 42 17 0,000 0,10666585 0,14216294 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,10666585 0,14208542 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,10666585 0,14200799 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,10666585 0,14193065 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,10666585 0,14185338 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,10666585 0,14177621 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,10666585 0,14169911 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,10666585 0,1416221 ! gas transport GO:0015669 26 17 0,000 0,10666585 0,14154517 ! organic cation transport GO:0015695 32 17 0,000 0,10666585 0,14146833 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,10666585 0,14139157 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,10666585 0,14131489 ! T cell activation GO:0042110 189 84 1,000 0,10679168 0,14140492 ! response to nutrient GO:0007584 135 84 1,000 0,10679168 0,14132832 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,11103644 0,14686628 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,11257497 0,1488207 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,11257497 0,14874022 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11257497 0,14865982 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,11257497 0,1485795 ! adult walking behavior GO:0007628 36 18 0,000 0,11257497 0,14849928 ! patterning of blood vessels GO:0001569 43 18 0,000 0,11257497 0,14841914 ! heart looping GO:0001947 34 18 0,000 0,11257497 0,14833908 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,11257497 0,14825912 ! centrosome cycle GO:0007098 26 18 0,000 0,11257497 0,14817924 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,11257497 0,14809944 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,11257497 0,14801973 ! glycine metabolic process GO:0006544 30 18 0,000 0,11257497 0,14794011 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11257497 0,14786057 ! response to retinoic acid GO:0032526 31 18 0,000 0,11257497 0,14778112 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,11257497 0,14770175 ! DNA integration GO:0015074 32 18 0,000 0,11257497 0,14762247 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,11257497 0,14754327 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,11257497 0,14746416 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,11257497 0,14738513 ! neural crest cell migration GO:0001755 41 18 0,000 0,11257497 0,14730619 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,11257497 0,14722733 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,11257497 0,14714856 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,11257497 0,14706987 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,11257497 0,14699127 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,11257497 0,14691275 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,11257497 0,14683431 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,11257497 0,14675596 ! detection of bacterium GO:0016045 22 18 0,000 0,11257497 0,14667769 ! microspike assembly GO:0030035 46 18 0,000 0,11257497 0,1465995 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,11257497 0,1465214 ! amine biosynthetic process GO:0009309 146 88 1,000 0,11532474 0,15002042 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,11532474 0,14994058 ! cellular defense response GO:0006968 123 89 1,000 0,11748464 0,15266754 ! protein localization in nucleus GO:0034504 192 89 1,000 0,11748464 0,15258638 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,11844518 0,15375216 ! positive regulation of translation GO:0045727 31 19 0,000 0,11844518 0,15367051 ! negative regulation of defense response GO:0031348 27 19 0,000 0,11844518 0,15358894 ! neuron maturation GO:0042551 46 19 0,000 0,11844518 0,15350746 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,11844518 0,15342607 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,11844518 0,15334476 GO:0019692|deoxyribose phosphate metabolic process, ! inositol metabolic process GO:0006020 33 19 0,000 0,11844518 0,15326354 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11844518 0,15318241 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,11844518 0,15310136 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,11844518 0,1530204 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,11844518 0,15293952 ! response to vitamin A GO:0033189 32 19 0,000 0,11844518 0,15285873 ! heme metabolic process GO:0042168 40 19 0,000 0,11844518 0,15277802 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,11844518 0,1526974 ! response to fungus GO:0009620 26 19 0,000 0,11844518 0,15261686 ! peptide cross-linking GO:0018149 39 19 0,000 0,11844518 0,15253641 ! protein export from nucleus GO:0006611 40 19 0,000 0,11844518 0,15245604 ! heart process GO:0003015 32 19 0,000 0,11844518 0,15237576 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,11844518 0,15229556 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,11844518 0,15221545 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,11844518 0,15213542 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,11844518 0,15205548 ! vitamin transport GO:0051180 31 19 0,000 0,11844518 0,15197561 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,11844518 0,15189584 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,11844518 0,15181614 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,11844518 0,15173653 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,11844518 0,15165701 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,11844518 0,15157756 ! cilium assembly GO:0042384 38 19 0,000 0,11844518 0,1514982 ! peptide hormone secretion GO:0030072 32 19 0,000 0,11844518 0,15141893 ! response to unfolded protein GO:0006986 139 90 1,000 0,11965473 0,1528852 ! protein secretion GO:0009306 45 20 0,000 0,12427672 0,1587078 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,12427672 0,15862488 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,12427672 0,15854205 ! positive regulation of ossification GO:0045778 50 20 0,000 0,12427672 0,1584593 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,12427672 0,15837664 ! skin development GO:0043588 42 20 0,000 0,12427672 0,15829407 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,12427672 0,15821158 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,12427672 0,15812918 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,12427672 0,15804686 ! response to vitamin GO:0033273 36 20 0,000 0,12427672 0,15796463 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,12427672 0,15788248 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,12427672 0,15780042 ! bile acid metabolic process GO:0008206 34 20 0,000 0,12427672 0,15771845 ! retinoid metabolic process GO:0001523 34 20 0,000 0,12427672 0,15763656 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,12427672 0,15755476 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,12427672 0,15747304 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,12427672 0,1573914 GO:0032392|DNA geometric change, ! body fluid secretion GO:0007589 33 20 0,000 0,12427672 0,15730985 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,12427672 0,15722839 ! peptide secretion GO:0002790 38 20 0,000 0,12427672 0,15714701 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,12427672 0,15706571 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,12427672 0,1569845 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,12427672 0,15690337 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,12427672 0,15682232 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,12427672 0,15674136 ! cell-cell junction organization GO:0045216 43 20 0,000 0,12427672 0,15666048 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,12427672 0,15657969 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,12427672 0,15649898 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,12427672 0,15641835 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,12427672 0,1563378 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,12427672 0,15625734 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,12427672 0,15617696 ! negative regulation of translation GO:0017148 32 20 0,000 0,12427672 0,15609667 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,12622386 0,15846089 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 1,000 0,12622386 0,1583795 ! regulation of cell killing GO:0031341 46 21 0,000 0,13006984 0,16312147 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,13006984 0,16303777 ! hormone secretion GO:0046879 39 21 0,000 0,13006984 0,16295416 ! cAMP metabolic process GO:0046058 41 21 0,000 0,13006984 0,16287064 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,13006984 0,1627872 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,13006984 0,16270385 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,13006984 0,16262058 ! smooth muscle contraction GO:0006939 48 21 0,000 0,13006984 0,1625374 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,13006984 0,16245431 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,13006984 0,16237129 ! plasma membrane fusion GO:0045026 33 21 0,000 0,13006984 0,16228837 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,13006984 0,16220552 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,13006984 0,16212277 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,13006984 0,16204009 ! sensory perception of pain GO:0019233 33 21 0,000 0,13006984 0,1619575 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,13006984 0,161875 ! collagen fibril organization GO:0030199 62 21 0,000 0,13006984 0,16179258 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,13006984 0,16171024 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,13006984 0,16162799 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,13006984 0,16154582 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,13006984 0,16146373 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,13006984 0,16138173 ! sperm-egg recognition GO:0035036 23 21 0,000 0,13006984 0,16129981 ! actin filament-based movement GO:0030048 47 21 0,000 0,13006984 0,16121797 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,13006984 0,16113622 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,13511182 0,1672976 ! transcription initiation GO:0006352 171 97 1,000 0,13511182 0,16721285 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,1358248 0,16801013 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,1358248 0,1679251 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,1358248 0,16784016 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,1358248 0,16775531 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,1358248 0,16767054 ! microtubule-based transport GO:0010970 59 22 0,000 0,1358248 0,16758586 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,1358248 0,16750126 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,1358248 0,16741675 ! cellular response to starvation GO:0009267 37 22 0,000 0,1358248 0,16733232 ! vacuolar transport GO:0007034 41 22 0,000 0,1358248 0,16724798 ! central nervous system neuron development GO:0021954 47 22 0,000 0,1358248 0,16716373 ! fucose metabolic process GO:0006004 44 22 0,000 0,1358248 0,16707956 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,1358248 0,16699547 ! stem cell differentiation GO:0048863 57 22 0,000 0,1358248 0,16691147 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,1358248 0,16682755 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,1358248 0,16674372 ! cytolysis GO:0019835 27 22 0,000 0,1358248 0,16665997 ! vasodilation GO:0042311 40 22 0,000 0,1358248 0,1665763 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,1358248 0,16649272 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,1358248 0,16640923 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,1358248 0,16632581 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,1358248 0,16624248 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,1358248 0,16615924 ! sarcomere organization GO:0045214 32 22 0,000 0,1358248 0,16607608 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,1358248 0,165993 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,1358248 0,16591 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,1358248 0,16582709 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,1358248 0,16574426 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,1358248 0,16566151 ! protein stabilization GO:0050821 41 22 0,000 0,1358248 0,16557884 ! leukocyte differentiation GO:0002521 232 98 1,000 0,13735543 0,16736126 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,14154186 0,17237625 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,14154186 0,17229036 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,14154186 0,17220456 ! gluconeogenesis GO:0006094 38 23 0,000 0,14154186 0,17211885 ! glycerol metabolic process GO:0006071 40 23 0,000 0,14154186 0,17203321 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,14154186 0,17194767 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,14154186 0,17186221 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,14154186 0,17177683 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,14154186 0,17169154 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,14154186 0,17160633 ! peroxisome organization GO:0007031 43 23 0,000 0,14154186 0,17152121 ! lysosome organization GO:0007040 47 23 0,000 0,14154186 0,17143617 ! vesicle targeting GO:0006903 49 23 0,000 0,14154186 0,17135122 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,14154186 0,17126635 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,14154186 0,17118156 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,14154186 0,17109686 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,14154186 0,17101225 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,14154186 0,17092771 ! fatty acid transport GO:0015908 47 23 0,000 0,14154186 0,17084326 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,14154186 0,17075889 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,14154186 0,17067461 ! hormone transport GO:0009914 41 23 0,000 0,14154186 0,17059041 ! cell-cell recognition GO:0009988 28 23 0,000 0,14154186 0,17050629 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,14154186 0,17042226 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,14154186 0,17033831 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,14154186 0,17025444 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,14722125 0,17699878 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,14722125 0,17691171 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,14722125 0,17682474 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,14722125 0,17673784 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,14722125 0,17665104 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,14722125 0,17656432 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,14722125 0,17647768 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,14722125 0,17639113 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,14722125 0,17630466 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,14722125 0,17621828 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,14722125 0,17613198 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,14722125 0,17604577 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,14722125 0,17595964 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,14722125 0,1758736 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,14722125 0,17578764 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,14722125 0,17570177 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,14722125 0,17561597 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,14722125 0,17553027 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,14722125 0,17544464 ! platelet activation GO:0030168 41 24 0,000 0,14722125 0,1753591 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,14722125 0,17527364 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,14722125 0,17518827 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,14722125 0,17510298 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,14722125 0,17501777 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,14722125 0,17493264 ! regulation of amine transport GO:0051952 41 24 0,000 0,14722125 0,1748476 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,15286323 0,18146009 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,15286323 0,18137196 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,15286323 0,18128391 ! phototransduction GO:0007602 37 25 0,000 0,15286323 0,18119595 ! keratinization GO:0031424 37 25 0,000 0,15286323 0,18110808 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,15286323 0,18102029 ! vacuole organization GO:0007033 49 25 0,000 0,15286323 0,18093259 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,15286323 0,18084497 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,15286323 0,18075744 ! receptor metabolic process GO:0043112 53 25 0,000 0,15286323 0,18066999 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,15286323 0,18058262 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,15286323 0,18049534 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,15286323 0,18040815 ! immunoglobulin production GO:0002377 62 25 0,000 0,15286323 0,18032103 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,15286323 0,18023401 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,15286323 0,18014706 ! liver development GO:0001889 55 25 0,000 0,15286323 0,1800602 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,15846803 0,18657224 ! initiation of viral infection GO:0019059 60 26 0,000 0,15846803 0,18648237 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,15846803 0,18639259 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,15846803 0,18630289 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,15846803 0,18621328 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,15846803 0,18612375 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,15846803 0,18603431 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,15846803 0,18594496 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,15846803 0,18585569 ! digestive system process GO:0022600 49 26 0,000 0,15846803 0,18576651 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,15846803 0,18567741 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,15846803 0,1855884 ! osteoblast differentiation GO:0001649 63 26 0,000 0,15846803 0,18549948 ! neural crest cell development GO:0014032 59 26 0,000 0,15846803 0,18541063 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,15846803 0,18532188 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,15846803 0,18523321 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,15846803 0,18514462 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,15846803 0,18505612 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,15846803 0,1849677 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,15846803 0,18487937 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,15846803 0,18479112 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,15846803 0,18470296 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,15846803 0,18461488 ! telomere organization GO:0032200 46 26 0,000 0,15846803 0,18452689 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,15846803 0,18443897 ! neural tube closure GO:0001843 58 26 0,000 0,15846803 0,18435115 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,15846803 0,1842634 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,15846803 0,18417574 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,16403591 0,19055622 ! embryonic pattern specification GO:0009880 49 27 0,000 0,16403591 0,19046566 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,16403591 0,19037517 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,16403591 0,19028478 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,16403591 0,19019447 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,16403591 0,19010424 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,16403591 0,1900141 ! iron ion transport GO:0006826 65 27 0,000 0,16403591 0,18992405 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,16403591 0,18983408 ! superoxide metabolic process GO:0006801 41 27 0,000 0,16403591 0,1897442 ! tube lumen formation GO:0035148 59 27 0,000 0,16403591 0,1896544 ! response to starvation GO:0042594 47 27 0,000 0,16403591 0,18956468 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,16403591 0,18947505 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,16403591 0,18938551 ! neuron fate commitment GO:0048663 52 28 0,000 0,16956711 0,19567901 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,16956711 0,19558662 ! vesicle docking GO:0048278 55 28 0,000 0,16956711 0,19549432 ! circadian rhythm GO:0007623 56 28 0,000 0,16956711 0,1954021 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,16956711 0,19530997 ! sperm motility GO:0030317 37 28 0,000 0,16956711 0,19521793 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,16956711 0,19512598 ! base-excision repair GO:0006284 41 28 0,000 0,16956711 0,19503411 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,16956711 0,19494233 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,16956711 0,19485064 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,16956711 0,19475903 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,16956711 0,19466751 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,16956711 0,19457607 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,16956711 0,19448472 ! glutathione metabolic process GO:0006749 42 28 0,000 0,16956711 0,19439346 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,16956711 0,19430228 ! lipid oxidation GO:0034440 48 28 0,000 0,16956711 0,19421118 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,16956711 0,19412018 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,17506187 0,20031669 ! translational initiation GO:0006413 66 29 0,000 0,17506187 0,20022291 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,17506187 0,20012922 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,17506187 0,20003561 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,17506187 0,1999421 ! primary neural tube formation GO:0014020 61 29 0,000 0,17506187 0,19984867 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,17506187 0,19975532 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,17506187 0,19966207 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,17506187 0,1995689 ! synaptogenesis GO:0007416 46 29 0,000 0,17506187 0,19947581 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,17506187 0,19938282 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,17506187 0,19928991 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,18052042 0,20540819 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,18052042 0,20531256 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,18052042 0,20521702 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,18052042 0,20512157 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,18052042 0,20502621 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,18052042 0,20493094 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,18052042 0,20483576 ! acute-phase response GO:0006953 50 30 0,000 0,18052042 0,20474066 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,18052042 0,20464565 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,18052042 0,20455074 ! myofibril assembly GO:0030239 50 30 0,000 0,18052042 0,2044559 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,18052042 0,20436116 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,18052042 0,20426651 ! cell fate determination GO:0001709 64 30 0,000 0,18052042 0,20417194 ! phospholipid transport GO:0015914 65 30 0,000 0,18052042 0,20407746 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,18052042 0,20398306 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,18052042 0,20388876 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,18052042 0,20379454 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,18594301 0,20981929 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,18594301 0,20972242 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,18594301 0,20962564 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,18594301 0,20952895 ! regulation of innate immune response GO:0045088 57 31 0,000 0,18594301 0,20943235 ! peptide transport GO:0015833 60 31 0,000 0,18594301 0,20933583 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,18594301 0,20923941 ! detection of light stimulus GO:0009583 44 31 0,000 0,18594301 0,20914308 ! natural killer cell activation GO:0030101 50 31 0,000 0,18594301 0,20904683 ! cofactor catabolic process GO:0051187 54 31 0,000 0,18594301 0,20895067 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,18594301 0,2088546 ! eye morphogenesis GO:0048592 65 31 0,000 0,18594301 0,20875862 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,18594301 0,20866273 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,19132986 0,21460921 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,19132986 0,21451072 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,19132986 0,21441232 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,19132986 0,21431401 ! muscle cell development GO:0055001 52 32 0,000 0,19132986 0,21421579 ! mesoderm formation GO:0001707 73 32 0,000 0,19132986 0,21411766 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,19132986 0,21401962 ! BMP signaling pathway GO:0030509 71 32 0,000 0,19132986 0,21392167 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,19132986 0,21382381 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,19132986 0,21372604 ! gene silencing GO:0016458 71 32 0,000 0,19132986 0,21362836 ! regulation of pH GO:0006885 56 33 0,000 0,19668122 0,21950307 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,19668122 0,21940284 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,19668122 0,2193027 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,19668122 0,21920266 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,19668122 0,2191027 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,19668122 0,21900284 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,19668122 0,21890306 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,19668122 0,21880338 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,19668122 0,21870379 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,19668122 0,21860429 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,19668122 0,21850488 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,20199732 0,22430884 ! cholesterol transport GO:0030301 62 34 0,000 0,20199732 0,22420693 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,20199732 0,22410511 ! spliceosome assembly GO:0000245 75 34 0,000 0,20199732 0,22400338 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,20199732 0,22390174 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,20199732 0,2238002 ! formation of primary germ layer GO:0001704 76 34 0,000 0,20199732 0,22369875 ! cell fate specification GO:0001708 56 34 0,000 0,20199732 0,22359739 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,20199732 0,22349613 ! adult locomotory behavior GO:0008344 62 34 0,000 0,20199732 0,22339495 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,20727838 0,22913171 ! negative regulation of secretion GO:0051048 68 35 0,000 0,20727838 0,22902808 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,20727838 0,22892454 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,20727838 0,2288211 ! membrane docking GO:0022406 69 35 0,000 0,20727838 0,22871775 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,20727838 0,22861449 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,20727838 0,22851132 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,20727838 0,22840825 ! ceramide metabolic process GO:0006672 72 35 0,000 0,20727838 0,22830527 ! sterol transport GO:0015918 63 35 0,000 0,20727838 0,22820238 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,20727838 0,22809959 ! vesicle localization GO:0051648 70 35 0,000 0,20727838 0,22799689 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,21252465 0,23366234 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,21252465 0,23355722 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,21252465 0,23345221 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,21252465 0,23334729 ! protein targeting to membrane GO:0006612 75 36 0,000 0,21252465 0,23324246 ! regulation of proteolysis GO:0030162 77 36 0,000 0,21252465 0,23313772 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,21252465 0,23303308 ! aerobic respiration GO:0009060 56 36 0,000 0,21252465 0,23292854 ! cytokine production GO:0001816 68 36 0,000 0,21252465 0,23282409 ! embryonic organ development GO:0048568 67 36 0,000 0,21252465 0,23271973 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,21252465 0,23261546 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,21252465 0,23251129 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,21773634 0,23810648 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,21773634 0,23799994 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,21773634 0,2378935 ! sister chromatid segregation GO:0000819 65 37 0,000 0,21773634 0,23778716 ! tissue remodeling GO:0048771 78 37 0,000 0,21773634 0,23768091 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,21773634 0,23757475 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,21773634 0,23746869 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,22291368 0,24300675 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,22291368 0,24289836 ! organic anion transport GO:0015711 82 38 0,000 0,22291368 0,24279007 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,22291368 0,24268187 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,22291368 0,24257377 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,22291368 0,24246577 ! spermatid development GO:0007286 69 38 0,000 0,22291368 0,24235786 ! neural tube formation GO:0001841 79 38 0,000 0,22291368 0,24225005 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,2280569 0,24772922 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,2280569 0,24761912 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,2280569 0,24750911 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,2280569 0,24739921 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,2280569 0,2472894 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,2280569 0,24717969 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,23316623 0,25260537 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,23316623 0,2524934 ! lipid homeostasis GO:0055088 75 40 0,000 0,23316623 0,25238152 ! mismatch repair GO:0006298 58 40 0,000 0,23316623 0,25226975 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,23316623 0,25215808 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,23316623 0,2520465 ! RNA export from nucleus GO:0006405 61 41 0,000 0,23824188 0,25741925 ! mRNA catabolic process GO:0006402 79 41 0,000 0,23824188 0,25730545 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,23824188 0,25719174 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,23824188 0,25707814 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,23824188 0,25696464 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,23824188 0,25685124 ! feeding behavior GO:0007631 69 41 0,000 0,23824188 0,25673794 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,23824188 0,25662474 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,23824188 0,25651164 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,23824188 0,25639864 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,23824188 0,25628574 ! RNA modification GO:0009451 64 41 0,000 0,23824188 0,25617294 ! organic ether metabolic process GO:0018904 59 42 0,000 0,24328408 0,26147955 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,24328408 0,26136456 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,24328408 0,26124967 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,24328408 0,26113489 ! regulation of protein secretion GO:0050708 77 42 0,000 0,24328408 0,26102021 ! cytokinesis GO:0000910 84 42 0,000 0,24328408 0,26090562 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,24829304 0,26616056 ! regulation of tube size GO:0035150 76 43 0,000 0,24829304 0,26604382 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,24829304 0,26592718 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,24829304 0,26581065 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,24829304 0,26569422 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,24829304 0,26557789 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,24829304 0,26546167 ! ion transmembrane transport GO:0034220 79 43 0,000 0,24829304 0,26534554 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,24829304 0,26522952 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,25326899 0,27042664 ! striated muscle contraction GO:0006941 85 44 0,000 0,25326899 0,2703085 ! phagocytosis GO:0006909 105 44 0,000 0,25326899 0,27019046 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,25326899 0,27007252 ! double-strand break repair GO:0006302 85 44 0,000 0,25326899 0,26995469 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,25821214 0,27510347 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,25821214 0,27498355 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,25821214 0,27486373 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,25821214 0,27474402 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,25821214 0,27462441 ! polyol metabolic process GO:0019751 77 45 0,000 0,25821214 0,2745049 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,26312271 0,27960364 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,26312271 0,27948207 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,26312271 0,27936061 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,26312271 0,27923926 ! neural tube development GO:0021915 91 47 0,000 0,2680009 0,28429275 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,27284694 0,28930776 ! endosome transport GO:0016197 127 48 0,000 0,27284694 0,28918224 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,27284694 0,28905684 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,27284694 0,28893154 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,27284694 0,28880636 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,27766103 0,29377475 ! regulation of ion transport GO:0043269 86 50 0,000 0,28244338 0,29870528 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,28244338 0,29857602 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,28244338 0,29844688 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,28244338 0,29831785 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,28244338 0,29818893 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,28244338 0,29806012 ! peptide metabolic process GO:0006518 80 51 0,000 0,28719421 0,30294277 ! Notch signaling pathway GO:0007219 111 52 0,000 0,29191371 0,30778817 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,29191371 0,30765539 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,29191371 0,30752273 ! excretion GO:0007588 87 52 0,000 0,29191371 0,30739017 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,29191371 0,30725773 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,29191371 0,30712541 ! amino acid activation GO:0043038 98 52 0,000 0,29191371 0,3069932 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,2966021 0,31178956 ! inner ear development GO:0048839 89 53 0,000 0,2966021 0,31165546 ! chromatin remodeling GO:0006338 122 53 0,000 0,2966021 0,31152147 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,2966021 0,3113876 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,2966021 0,31125384 ! regulation of translational initiation GO:0006446 87 54 0,000 0,30125958 0,31600565 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,30125958 0,31587002 ! membrane fusion GO:0006944 122 54 0,000 0,30125958 0,31573451 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,30125958 0,31559912 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,30125958 0,31546384 ! RNA catabolic process GO:0006401 103 55 0,000 0,30588635 0,32017153 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,30588635 0,32003441 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,30588635 0,31989741 ! cell recognition GO:0008037 98 55 0,000 0,30588635 0,31976052 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,30588635 0,31962376 ! RNA elongation GO:0006354 90 56 0,000 0,31048261 0,32428773 ! chloride transport GO:0006821 102 57 0,000 0,31504856 0,32891608 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,31504856 0,32877558 ! regulation of actin filament length GO:0030832 118 58 0,000 0,31958441 0,33336666 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,31958441 0,33322437 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,31958441 0,33308221 ! gastrulation GO:0007369 122 58 0,000 0,31958441 0,33294017 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,31958441 0,33279826 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,31958441 0,33265646 ! nuclear export GO:0051168 110 59 0,000 0,32409034 0,33720303 ! establishment of organelle localization GO:0051656 122 59 0,000 0,32409034 0,33705948 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,32856657 0,34156941 ! regulation of endocytosis GO:0030100 104 60 0,000 0,32856657 0,34142413 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,32856657 0,34127896 ! adult behavior GO:0030534 104 60 0,000 0,32856657 0,34113392 ! positive regulation of secretion GO:0051047 110 61 0,000 0,33301327 0,34560383 ! regulation of cellular component size GO:0032535 125 61 0,000 0,33301327 0,34545708 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,33301327 0,34531045 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,33301327 0,34516395 ! camera-type eye development GO:0043010 126 61 0,000 0,33301327 0,34501757 ! proton transport GO:0015992 117 61 0,000 0,33301327 0,34487131 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,33743065 0,34929792 ! tRNA processing GO:0008033 102 62 0,000 0,33743065 0,34914997 ! regulation of mitosis GO:0007088 112 63 0,000 0,3418189 0,35354089 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,3418189 0,35339127 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,3418189 0,35324178 ! hydrogen transport GO:0006818 121 64 0,000 0,34617821 0,3575955 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,34617821 0,35744436 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,35050876 0,36176295 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,35050876 0,36161018 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,35050876 0,36145754 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,35481076 0,36573953 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,35908437 0,36998867 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,35908437 0,36983268 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,35908437 0,36967683 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,35908437 0,36952112 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,36332981 0,37373251 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,36332981 0,37357522 ! adaptive immune response GO:0002250 126 68 0,000 0,36332981 0,37341806 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,36754723 0,37759373 ! single fertilization GO:0007338 83 69 0,000 0,36754723 0,37743501 ! cell redox homeostasis GO:0045454 114 70 0,000 0,37173684 0,38157694 ! activation of immune response GO:0002253 120 70 0,000 0,37173684 0,38141668 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,37173684 0,38125655 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,37589882 0,38536333 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,37589882 0,38520168 ! appendage morphogenesis GO:0035107 150 72 0,000 0,38003334 0,38927524 GO:0035108|limb morphogenesis, ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,38003334 0,38911209 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,38003334 0,38894907 ! appendage development GO:0048736 151 73 0,000 0,38414058 0,39298804 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,38414058 0,39282354 ! regulation of immune effector process GO:0002697 156 73 0,000 0,38414058 0,39265918 ! acute inflammatory response GO:0002526 118 74 0,000 0,38822073 0,39666384 ! organelle localization GO:0051640 155 74 0,000 0,38822073 0,39649801 ! transition metal ion transport GO:0000041 143 75 0,000 0,39227396 0,40047024 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,39227396 0,40030296 ! eye development GO:0001654 155 75 0,000 0,39227396 0,40013582 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,39630045 0,40407429 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,39630045 0,40390572 ! regulation of blood pressure GO:0008217 134 76 0,000 0,39630045 0,40373728 ! amine catabolic process GO:0009310 136 77 0,000 0,40030038 0,40764228 ! neurotransmitter transport GO:0006836 142 77 0,000 0,40030038 0,40747243 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,40030038 0,40730272 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,40030038 0,40713315 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,40427392 0,4110034 ! antigen processing and presentation GO:0019882 117 78 0,000 0,40427392 0,41083244 ! fertilization GO:0009566 99 78 0,000 0,40427392 0,41066161 ! blood coagulation GO:0007596 151 79 0,000 0,40822123 0,41449895 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,40822123 0,41432675 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,40822123 0,41415468 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,41214251 0,41795938 ! muscle cell differentiation GO:0042692 178 81 0,000 0,41603791 0,4217347 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,41603791 0,42155977 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,42375177 0,429198 ! exocytosis GO:0006887 153 83 0,000 0,42375177 0,42902013 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,42375177 0,42884241 ! inorganic anion transport GO:0015698 156 83 0,000 0,42375177 0,42866484 ! digestion GO:0007586 130 84 0,000 0,42757057 0,43234888 ! hemostasis GO:0007599 165 85 0,000 0,43136416 0,43600441 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,43136416 0,43582409 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,43136416 0,43564392 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,43513273 0,43926828 ! regulation of lyase activity GO:0051339 169 86 0,000 0,43513273 0,43908684 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,43887642 0,4426817 ! nucleosome assembly GO:0006334 126 87 0,000 0,43887642 0,442499 ! cellular respiration GO:0045333 143 88 0,000 0,4425954 0,44606459 ! sensory perception of smell GO:0007608 117 88 0,000 0,4425954 0,44588065 ! chromatin assembly GO:0031497 128 88 0,000 0,4425954 0,44569685 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,44628984 0,44923201 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,4499599 0,45273972 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,45360573 0,45622018 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,45360573 0,45603243 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,45722751 0,45948449 ! vitamin metabolic process GO:0006766 153 93 0,000 0,46082537 0,4629097 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,46439949 0,46630824 ! sterol metabolic process GO:0016125 166 94 0,000 0,46439949 0,46611666 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,46439949 0,46592524 ! nucleosome organization GO:0034728 143 95 0,000 0,46795001 0,4692947 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,46795001 0,46910213 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,46795001 0,46890971 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,46795001 0,46871746 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,46795001 0,46852536 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,47846158 0,4788536 ! mRNA transport GO:0051028 185 100 0,000 0,48535415 0,4855529 ! positive regulation of immune response GO:0050778 175 100 0,000 0,48535415 0,48535415